Pubmed Text
Collection
Collection of pubmed 2024 papers. • 11 items • Updated
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36196001 | Targeting cluster of differentiation 26 / dipeptidyl peptidase 4 (CD26/DPP4) in organ fibrosis. | Cluster of differentiation 26 (CD26)/dipeptidyl peptidase 4 (DPP4) is an exopeptidase that is expressed as a transmembrane protein in many organs but also present in a circulating soluble form. Beyond its enzymatic and costimulatory activity, CD26/DPP4 is involved in the pathogenesis of chronic fibrotic diseases across... |
36196002 | Epilepsy in KBG syndrome. | To illustrate the epileptological and electroencephalographic (EEG) characteristics of a cohort of patients with KBG syndrome and epilepsy. |
36196003 | Synthesis of Axially Chiral Biaryls via Enantioselective Ullmann Coupling of ortho-Chlorinated Aryl Aldehydes Enabled by a Chiral 2,2'-Bipyridine Ligand. | The first nickel-catalyzed highly enantioselective reductive Ullmann coupling of ortho-chlorinated aryl aldehyde was achieved under mild reaction conditions with a chiral 2,2'-bipyridine ligand (+)-DTB-SBpy, thus providing axially chiral biphenyl or binaphthyl dials with up to 99 % yield and 99.5:0.5 er. The versatilit... |
36196004 | Voltage mapping and pulmonary vein isolation in master athletes with atrial fibrillation. | Master athletes pass a wide range of exercise enthusiasts. At the extreme, there is an increased risk of atrial fibrillation (AF). Therapies aimed at rate or rhythm control are often limited given unfavorable side effects. Although studies suggest an increase in left atrial (LA) fibrosis in this population, minimal ele... |
36196007 | Maternal Periconceptional Folic Acid Supplementation and DNA Methylation Patterns in Adolescent Offspring. | Folate, including the folic acid form, is a ponent of the one-carbon metabolic pathway used for DNA methylation. Changes in DNA methylation patterns during critical development periods are associated with disease es and are associated with changes in nutritional status in pregnancy. The long-term impact of periconcepti... |
36196006 | Evolution of p-coumaroylated lignin in eudicots provides new tools for cell wall engineering. | Ester-linked p-coumarate (pCA) is a hallmark feature of the secondary cell walls melinid monocot plants. It has been shown that pCA groups arise during lignin polymerisation from the participation of monolignol conjugates assembled by p-coumaroyl-CoA:monolignol transferase (PMT) enzymes, members of the BAHD superfamily... |
36196009 | Hydrogen-Bonded Organic Framework for High-Performance Lithium/Sodium-Iodine Organic Batteries. | The rechargeable lithium/sodium-iodine battery (Li/Na-I |
36196011 | Carbon dioxide automated digital subtraction angiography for endovascular arteriovenous fistulas creation. | Recent literature shows how residual renal function (RKF), defined as the urinary clearance of urea and creatinine, is associated with a lower mortality risk in HD patients. The use of non-nephrotoxic contrast media during radiological procedure, may be useful for preservation of RKF in patients with chronic kidney dis... |
36196008 | Dual Activation of Molecular Oxygen and Surface Lattice Oxygen in Single Atom Cu | The in-depth mechanism on the simultaneous activation of O |
36196010 | Ectopic adrenocorticotropic hormone-secreting carcinoid with solitary cryptococcosis in the lungs. | Carcinoid tumors can on rare occasions ectopically produce adrenocorticotropic hormone (ACTH), causing Cushing's syndrome, and patients could e promised. Care must therefore be taken regarding plications. In particular, ACTH-producing pulmonary carcinoid is not easy to diagnose by itself, and bined with pulmonary nodul... |
36196013 | Unraveling the Synergistic Reaction and the Deactivation Mechanism for the Catalytic Degradation of Double Components of Sulfur-Containing VOCs over ZSM-5-Based Materials. | petitive adsorption behavior, the synergistic catalytic reaction, and deactivation mechanisms under ponents of sulfur-containing volatile pounds (VOCs) are a bridge to solve their actual pollution problems. However, they are still unknown. Herein, simultaneous catalytic position of methyl mercaptan (CH |
36196014 | The Functional Roles of | Probiotics are live microorganisms that can be consumed by humans in amounts sufficient to offer health-promoting effects. Owing to their various biological functions, probiotics are widely used in biological engineering, industry and agriculture, food safety, and the life and health fields. |
36196015 | Total robotic right hepatectomy for multifocal hepatocellular carcinoma using vessel sealer. | Rapid adoption of a robotic approach as a minimally invasive surgery tool has enabled surgeons to perform plex hepatobiliary surgeries than conventional laparoscopic surgery. Although various types of liver resections have been performed robotically, parenchymal transection is challenging monly used instruments (Cavitr... |
36196017 | Obesity and diabetes in people of African ancestry with HIV. | Obesity is a chronic disease with multiple adverse effects on health. The prevalence of obesity is increasing worldwide, and people of African ancestry are disproportionally affected. Several widely used antiretrovirals have been associated with weight gain and contribute to the rising burden of obesity in people with ... |
36196018 | The Association of Avoidance Coping with Gestational Weight Gain among Pregnant Black Women. | Gestational weight gain (GWG) outside mended parameters can lead to pregnancy or plications. Avoidance coping may influence GWG. We examined the association of avoidance coping with GWG among a sample of 112 pregnant Black women in the Midwest. pleted avoidance coping questionnaires at three time points throughout preg... |
36196020 | Transition-Metal-Free Dehydropolymerization of Phosphine-Boranes at Ambient Temperature. | Stoichiometric reaction of phosphine-borane adducts RR'PH⋅BH |
36196019 | A Novel Technique for the Treatment of Inferior Pole Fractures of the Patella: A Preliminary Report. | Most inferior pole fractures of the patella minuted. Therefore, an ideal treatment method has not been determined. We have presented a modified tension band fixation technique-the Krachow suturing, Nice bined with tension band fixation-and reported the results of the procedure. |
36196021 | Low-Cost and Scalable Ni-Prussian Blue Analogue//Functionalized Carbon Based Na-Ion Systems for all Climate Operations. | Herein, we have developed a sodium ion based aqueous energy storage device with nickel prussian-blue-analogue (Ni-PBA) positive and functionalized carbon-black negative electrodes in 1 M Na |
36196023 | RNA N | Epigenetic modifications have received increasing attention and have been shown to be extensively involved in kidney development and disease progression. Among them, the mon RNA modification, N |
36196024 | Cigarette Smoking Cessation Counselling in Pregnant Smokers with Mental Illness/Substance Use Disorders. | Our objective was to determine if past-year mental illness and substance use disorders (SUD) among pregnant smokers predicted the probability of receipt of counselling for cigarette smoking cessation. A secondary analysis of data from the National Survey on Drug Use and Health 2016-2019 was conducted. We found that app... |
36196022 | Genetic and molecular architecture of familial hypercholesterolemia. | Atherosclerotic cardiovascular disease is the leading cause of death globally. Despite its important risk of premature atherosclerosis and cardiovascular disease, familial hypercholesterolemia (FH) is still largely underdiagnosed worldwide. It is one of the most frequently inherited diseases due to mutations, for autos... |
36196025 | HIV treatment strategies across Central, Eastern and Southeastern Europe: New times, old problems. | In the last decade, substantial differences in the epidemiology of, antiretroviral therapy (ART) for, cascade of care in and support to people with HIV in vulnerable populations have been observed between countries in Western Europe, Central Europe (CE) and Eastern Europe (EE). The aim of this study was to use a survey... |
36196026 | Performance of Xpert MTB/RIF for Diagnosis of Tuberculosis in HIV-Infected People in China: A Retrospective, Single-Center Study. | BACKGROUND There are few studies of GeneXpert MTB/RIF (hereafter referred to as Xpert) detection technology in HIV-infected people in China. Therefore, this study aimed to evaluate the value of Xpert in HIV/TB co-infected patients and to provide reference and guidance for the diagnosis of TB in HIV-infected populations... |
36196027 | Pushing the Boundaries: Drug-Coated Balloons to Treat a Calcified and Thrombotic Lesion in Acute Coronary Syndrome. | BACKGROUND Use of drug-coated balloons (DCB) is an important research topic. panies are quickly developing new, cutting-edge technologies and means to deliver drugs. Moreover, interest is growing in use of sirolimus-coated balloons, a promising technology in the "leaving nothing behind" era. This, bination with interes... |
36196028 | Modeling Photolytic Decomposition of Energetically Functionalized Dodecanes. | The photolytic stability of explosives and energetic functional groups is of importance for those who regularly handle or are exposed to explosives in typical environmental conditions. This study models the photolytic degradation of dodecane substituted with various energetic functional groups: azide, nitro, nitrate es... |
36196030 | Colombian ocular infectious epidemiology study (COIES): presumed ocular tuberculosis incidence and sociodemographic characterization, 2015-2020. | This study aims to describe the incidence and geographical distribution of presumed ocular tuberculosis (POTB) in Colombia between 2015 and 2020 based on the Colombian Ministry of Health and Social Protection data. |
36196031 | Outcomes and Risk Factors for Complications in Cataract Patients with Hepatitis C Virus Infection. | To describe es of patients with hepatitis C virus (HCV) seropositivity undergoing cataract surgery, as well as investigate risk factors for plications. |
36196032 | Antibiotic Initiation Timing and Mortality in Trauma Patients With Ventilator-Associated Pneumonia. | Early antibiotic initiation is considered a cornerstone in the management of ventilator-associated pneumonia (VAP). However, recent data suggests that early antibiotic initiation may not be necessary in all cases. Additionally, the benefits of early antibiotic administration for infection have not been studied in a ded... |
36196029 | Investigating the Link Between IADL and Depressive Symptoms in Older Adults: A Cross-Sectional Serial Mediation Model. | There is a dearth of research on the psychological processes that underlie the negative relation between impaired instrumental activities of daily living (IADL) and depressive symptoms in older adults. Drawing on the stress process model and the resilience framework, we investigated whether purpose in life and resilien... |
36196033 | Dosimetric validation of a GPU-based dose engine for a fast in silico patient-specific quality assurance program in light ion beam therapy. | With rapid evolutions of fast and sophisticated calculation techniques and delivery technologies, clinics are almost facing a daily patient-specific (PS) plan adaptation, which would make a conventional experimental quality assurance (QA) workflow unlikely to be routinely feasible. Therefore, in silico approaches are f... |
36196034 | Prognostic value of right ventricular refractory period heterogeneity in Type-1 Brugada electrocardiographic pattern. | To investigate the prognostic significance of heterogeneity in the refractoriness of right ventricular (RV) outflow tract (RVOT) and RV apex at the electrophysiological study (EPS) in Brugada syndrome (BrS). |
36196035 | Six case reports of NTHL1-associated tumor syndrome further support it as a multi-tumor predisposition syndrome. | NTHL1-associated tumor syndrome (NATS) is an autosomal recessive condition characterized by an increased risk for colorectal polyposis and colorectal cancer (CRC). Only 46 case reports have been previously published. In a retrospective review, we analyzed the clinical histories of six patients found to have NATS after ... |
36196037 | Identifying and Interpreting Geometric Configuration-Dependent Activity of Spinel Catalysts for Water Reduction. | The catalytic activity of transition metal-based catalysts is overwhelmingly dependent on the geometric configuration. Identification and interpretation of different geometric configurations' contributions to catalytic activity plays a pivotal role in catalytic performance elevation. Spinel structured AB |
36196038 | Setting the top 10 eating disorder research and translation priorities for Australia. | People with eating disorders, as well as their caregivers, experience high symptom burden, reduced quality of life and increased risk of early mortality. A lack of resources, disjointed vision and limited uptake of the evidence have limited the translation and implementation of research into practice. Little is known a... |
36196039 | Assessment of pulmonary morphometry using hyperpolarized | Hyperpolarized (HP) |
36196040 | Disentangling direct and indirect effects of landscape structure on urban bird richness and functional diversity. | As fragmented landscapes e mon around the world, managing the spatial arrangement of landscape elements (i.e., landscape configuration) may help to promote the conservation of biodiversity. However, the relative effects of landscape configuration on different dimensions of biodiversity across species assemblages are la... |
36196041 | Accuracy and clinical use of biliary point-of-care ultrasound: A retrospective cohort study. | To assess the utilisation and diagnostic accuracy of biliary point-of-care ultrasounds (POCUS) performed and archived in a single New Zealand ED. |
36196042 | Malignant melanoma treatment using brachytherapy: Two case reports and 15 case series. | Malignant melanoma (MM) is usually resistant to radiotherapy. Brachytherapy may be an option in patients with bleeding or pain, and those in whom surgery is difficult. Brachytherapy has few side effects and can be used bination with external beam radiotherapy or chemotherapy. We summarize the demographic and clinical c... |
36196043 | Anatomical considerations and clinical interpretation of the 12-lead ECG in the prone position: a prospective multicentre study. | The aim of this study is to provide guidance for the clinical interpretation of electrocardiograms (ECGs) in prone position and to establish the electroanatomic explanations for the possible differences to supine position ECGs that may be observed. Additionally, to determine if prone back ECG can be used as an alternat... |
36196044 | False negatives in the newborn screening for cystic fibrosis in Western Andalusia: Results from a 10-year experience. | Cystic fibrosis (CF) is the mon autosomal recessive disorder in the Caucasian population, with an incidence of 1:5000 live births. In 2011, the screening of CF was implemented in the Andalusian Public Health newborn screening program by using immunoreactive trypsinogen and chloride sweat test (IRT/IRT/sweat test) deter... |
36196045 | Multi-scale cascaded networks for synthesis of mammogram to decrease intensity distortion and increase model-based perceptual similarity. | Synthetic digital mammogram (SDM) is a 2D image generated from digital breast tomosynthesis (DBT) and used as a substitute for a full-field digital mammogram (FFDM) to reduce the radiation dose for breast cancer screening. The previous deep learning-based method used FFDM images as the ground truth, and trained a singl... |
36196047 | Epidemiology of inherited epidermolysis bullosa in Germany. | Epidermolysis bullosa (EB) is a rare genetic disorder manifesting with skin and mucosal membrane blistering in different degrees of severity. |
36196048 | Preclinical studies in Krabbe disease: A model for the investigation of novel combination therapies for lysosomal storage diseases. | Krabbe disease (KD) is a lysosomal storage disease (LSD) caused by mutations in the galc gene. There are over 50 monogenetic LSDs, which largely impede the normal development of children and often lead to premature death. At present, there are no cures for LSDs and the available treatments are generally insufficient, s... |
36196049 | The complex relationship between greenspace and well-being in children with and without autism. | Greenspace (defined here as canopy coverage) positively correlates with improved well-being in typically developing individuals, but this relationship has not been established in children with autism spectrum disorder (ASD). To investigate this relationship, the current study merged data from the National Survey of Chi... |
36196050 | Coping strategies among women exposed to Gender-Based violence in Turkey. | To understand coping strategies used by women experiencing gender-based violence and living in Turkey. Coping is a cognitive and behavioural strategy that individuals develop to manage stress, generally categorized as emotion-focused or problem-focused coping. Women exposed to gender-based violence develop various copi... |
36196052 | Strategies for the enhancement of nail plate permeation of drugs to treat onychomycosis. | Onychomycosis is caused by dermatophytes, non-dermatophytes and yeasts. It has a global prevalence of 5.5%, requires long treatment periods, and has high relapse rates following therapy. Oral antifungals are generally the mon treatment. While effective, they have limitations such as drug-drug interactions, hepatotoxici... |
36196053 | Internet addiction is associated with psychological distress in highly schizotypal students. | There is some limited evidence of an association between technology addictions and emergence of pre-psychotic symptoms, high psychoticism, psychotic like experiences and high schizotypy among young non-clinical adults. These addictions and their subsequent distress are likely to contribute to transition to psychosis in... |
36196054 | Direct observation of chemo-mechanical coupling in DnaK by single-molecule force experiments. | Protein allostery requires munication channel for functional regulation between distal sites within a protein. In the molecular chaperone Hsp70, a two-domain enzyme, the ATP/ADP status of an N-terminal nucleotide-binding domain regulates the substrate affinity of a C-terminal substrate-binding domain. Recently availabl... |
36196055 | Effects of ligand binding on dynamics of fatty acid binding protein and interactions with membranes. | Intracellular transport of fatty acids involves binding of ligands to their carrier fatty acid binding proteins (FABPs) and interactions of ligand-free and -bound FABPs with membranes. Previous studies focused on ligand-free FABPs. Here, our amide hydrogen exchange data showed that oleic acid binding to human intestina... |
36196056 | Alterations induced by the PML-RARα oncogene revealed by image cross correlation spectroscopy. | The molecular mechanisms that underlie oncogene-induced genomic damage are still poorly understood. To understand how oncogenes affect chromatin architecture, it is important to visualize fundamental processes such as DNA replication and transcription in intact nuclei and quantify the alterations of their spatiotempora... |
36196057 | von Willebrand factor unfolding mediates platelet deposition in a model of high-shear thrombosis. | Thrombosis under high-shear conditions is mediated by the mechanosensitive blood glycoprotein von Willebrand factor (vWF). vWF unfolds in response to strong flow gradients and facilitates rapid recruitment of platelets in flowing blood. While the thrombogenic effect of vWF is well recognized, its conformational respons... |
36196058 | Homologous pairing in short double-stranded DNA-grafted colloidal microspheres. | Homologous pairing (HP), i.e., the pairing of similar or identical double-stranded DNA, is an insufficiently understood fundamental biological process. HP is now understood to also occur without protein mediation, but crucial mechanistic details remain poorly established. Unfortunately, systematic studies of sequence d... |
36196060 | Association of time-to-intravenous furosemide with mortality in acute heart failure: data from REPORT-HF. | Acute heart failure can be a life-threatening medical condition. Delaying administration of intravenous furosemide (time-to-diuretics) has been postulated to increase mortality, but prior reports have been inconclusive. We aimed to evaluate the association between time-to-diuretics and mortality in the international RE... |
36196061 | Evaluation of Substance Use Disorder Readmission and Length of Hospital Stay in a Major Rehabilitation Center in the Gulf States: a Retrospective Cohort Study. | Substance use disorders (SUDs) patients have longer lengths of hospital stay, and more unplanned readmissions than other hospitalized patients. We aim to evaluate SUD-related rehospitalization and length of hospital stay in a major rehabilitation center that serves countries of the Gulf States. In a retrospective cohor... |
36196059 | A chromosome-level genome assembly for Dracaena cochinchinensis reveals the molecular basis of its longevity and formation of dragon's blood. | Dracaena, a remarkably long-lived and slowly maturing species of plant, is world famous for its ability to produce dragon's blood, a precious traditional medicine used by different cultures since ancient times. However, there is no detailed and high-quality genome available for this species at present; thus, the molecu... |
36196062 | Subjective variables in travel behavior models: a critical review and Standardized Transport Attitude Measurement Protocol (STAMP). | Understanding people's travel behavior is necessary for achieving goals such as increased bicycling and walking, decreased traffic congestion, and adoption of clean-fuel vehicles. To understand underlying motivations, researchers increasingly are adding subjective variables to models of travel behavior. This article pr... |
36196063 | Research on metallic glasses at the atomic scale: a systematic review. | Metallic glasses (MGs) have been long investigated in material science to understand the origin of their remarkable properties. With the help putational simulations, researchers have delved into structure-property relationships, leading to a large number of reports. To quantify the available literature, we employed sys... |
36196064 | Postoperative nosocomial COVID-19 infection in surgical patients during pandemic: A prospective observational cohort study. | Background: increased pressure on healthcare systems and possible risk of ial COVID-19 infection during pandemic urged many guidelines to severely restrict the number of operations. The aim of this study was to investigate the risk of COVID-19 infection and plications in patients undergoing urgent or elective operation... |
36196065 | Using Implementation Science to Inform Workforce and Service Development in Youth Mental Health: An Australian Case Study. | Globally, mental illness and substance use disorders are the leading cause of disability and disease burden for young people. Orygen is an Australian youth mental health organisation with a mission to reduce the impact of mental ill health on young people, families and society, through research, clinical services, advo... |
36196066 | The Effect of Self-Administration of Medication During Hospitalization on Patient's Self-Efficacy and Medication Adherence After Discharge. | The effect of self-administration of medication (SAM), in which capable hospitalized patients administer medication themselves on medication self-efficacy is inconclusive. The aim of this study was to evaluate the effect of SAM on medication self-efficacy, adherence and patient satisfaction. |
36196067 | Perceptions of Participants on Trial Participation and Adherence to Tai Chi: A Qualitative Study. | Trial participation and adherence to interventions can directly influence the evaluation of es in clinical trials for real world applications. The factors that influence trial participation and adherence to Tai Chi interventions in people with cardiovascular diseases remains unknown. This study aimed to explore partici... |
36196068 | Quantitative trait locus mapping of fruit aroma compounds in cucumber ( | The fresh and unique flavor of cucumber fruits, posed of aldehydes and alcohols, is one of its most important fruit qualities. However, little is known about the genetic basis of pounds in cucumber fruit and the related quantitative trait loci (QTLs). In this study, genomic screening of QTLs underlying pounds was perfo... |
36196069 | The identification of the | This study aims to: (i) identify the |
36196070 | Correction to: Co-silencing of ABA receptors (SlRCAR) reveals interactions between ABA and ethylene signaling during tomato fruit ripening. | [This corrects the article DOI: 10.1093/hr/uhac057.]. |
36196071 | Biogeographic and metabolic studies support a glacial radiation hypothesis during | Chrysanthemum ( |
36196072 | Flipping the grant application review process. | The return on research investment resulting from new breakthrough scientific discoveries may be decreasing over time due to the law of diminishing returns, the relative decrease of research funding in terms of purchasing power parity, and various activities gaming the system. By altering the grant-review process, the m... |
36196073 | When Water Quality Crises Drive Change: A Comparative Analysis of the Policy Processes Behind Major Water Contamination Events. | The occurrence of major water contamination events across the world have been met with varying levels of policy responses. Arsenic-a priority water contaminant globally, occurring naturally in groundwater, causing adverse health effects-is widespread in Bangladesh. However, the policy response has been slow, and marked... |
36196074 | Public perception of urban wildlife during a COVID-19 stay-at-home quarantine order in Chicago. | Reduced human activity to mitigate the spread of the COVID-19 pandemic was panied by reports of unusual wildlife sightings in highly developed areas. Such experiences with urban nature may have helped residents cope with the stress of the pandemic and increased public interest in urban wildlife; however, this may depen... |
36196075 | Puerarin improves skeletal muscle strength by regulating gut microbiota in young adult rats. | Sarcopenia is an age-related skeletal muscle dysfunction syndrome that is lacking validated treatments. Maximizing muscle strength in young adulthood may be a promising way to prevent sarcopenia in the elderly. The phytomolecule puerarin has been extensively used in clinical practice and reported to increase energy met... |
36196076 | Correlations between paraspinal extensor muscle endurance and clinical outcomes in preoperative LSS patients and clinical value of an endurance classification. | Few study has investigated how paraspinal muscle endurance deteriorates in lumbar spinal stenosis (LSS) patients. In addition, little information is available on the relationship between clinical es and the endurance of paraspinal muscles. |
36196078 | $ over Ethics: Higher Education and the Private Prions Industry, a Symptom of the Theology of Neoliberalism. | Neoliberalism's impact on our everyday lives, culture, and institutions is powerful and ubiquitous. One might suspect that higher education, especially non-profit colleges and universities, would be less affected and more resistant to the expansion of market-driven logic and the hyper-capitalist ethos of neoliberalism,... |
36196080 | Evidence and consensus on technical aspects of embryo transfer. | Ultrasound-guided embryo transfer (US-GET) is a widely performed procedure, but standards for the best practice are not available. |
36196081 | ESHRE certification of ART centres for good laboratory and clinical practice. | Three years after the start of the ESHRE ART Centre Certification (ARTCC) programme, what is the current state of the system, in terms of the interest expressed in it and experiences during the assessment of ART services? |
36196079 | Surgical Rescue in a High-volume Urban Emergency General Surgery Service at a Middle-income Country. | The capacity for prompt "rescue" from death in patients plications has e an important marker of the quality of care since mortality and morbidity have been identified as incongruous indicators. This study aims to describe the incidence of "surgical rescue" failure and the es of emergency general surgery (EGS) patients ... |
36196082 | Nationwide evaluation of energy and indoor air quality predictive control and impact on infection risk for cooling season. | Since the coronavirus disease 2019, the extended time indoors makes people more concerned about indoor air quality, while the increased ventilation in seeks of reducing infection probability has increased the energy usage from heating, ventilation, and air-conditioning systems. In this study, to represent the dynamics ... |
36196083 | Reduced RNA adenosine-to-inosine editing in hippocampus vasculature associated with Alzheimer's disease. | Alzheimer's disease is the mon form of dementia and recent studies identify a type 1 interferon response in Alzheimer's disease possibly driving neuro-inflammation and other Alzheimer's disease pathologies. Loss of adenosine-to-inosine editing of endogenous Alu RNAs results in accumulation of Alu double-stranded RNAs, ... |
36196084 | Regional rather than global brain age mediates cognitive function in cerebral small vessel disease. | The factors and mechanisms underlying the heterogeneous cognitive es of cerebral small vessel disease are largely unknown. Brain biological age can be estimated by machine learning algorithms that use large brain MRI data sets to integrate pute neuroimaging-derived age-related features. Predicted and chronological ages... |
36196085 | Brain network dynamics codify heterogeneity in seizure evolution. | Dynamic functional brain connectivity facilitates adaptive cognition and behaviour. Abnormal alterations within such connectivity could result in disrupted functions observed across various neurological conditions. As one of the mon neurological disorders, epilepsy is defined by the seemingly random occurrence of spont... |
36196086 | Diaphragmatic pacing for the prevention of sudden unexpected death in epilepsy. | Sudden unexpected death in epilepsy is the leading cause of epilepsy related death. Currently, there are no reliable methods for preventing sudden unexpected death in epilepsy. The precise pathophysiology of sudden unexpected death in epilepsy is unclear; however, convergent lines of evidence suggest that seizure-induc... |
36196087 | Microstructural deficits of the thalamus in major depressive disorder. | Macroscopic structural abnormalities in the thalamus and thalamic circuits have been implicated in the neuropathology of major depressive disorder. However, cytoarchitectonic properties underlying these macroscopic abnormalities remain unknown. Here, we examined systematic deficits of brain architecture in depression, ... |
36196088 | The reduction of astrocytic tau prevents amyloid-β-induced synaptotoxicity. | Alzheimer's disease is a neurological disorder characterized by the overproduction and aggregation of amyloid-beta and the phosphorylation and intraneuronal accumulation of tau. These events promote synaptic dysfunction and loss, leading to neurodegeneration and cognitive deficits. Astrocytes are intimately associated ... |
36196089 | Targeted transcript analysis in muscles from patients with genetically diverse congenital myopathies. | Congenital myopathies are a group of early onset muscle diseases of variable severity often with characteristic muscle biopsy findings and involvement of specific muscle types. The clinical diagnosis of patients typically relies on histopathological findings and is confirmed by genetic analysis. The monly mutated genes... |
36196091 | Risk Factors for Urologic Complications After Kidney Transplantation and Impact in Graft Survival. | Kidney transplantation (KT) is the best therapy for chronic kidney disease (CKD). Major plications (MUCs) are the second etiology associated to morbidity and graft loss following KT, after rejection episodes. The objective of this study was to estimate the incidence, risk factors and impact on graft survival associated... |
36196094 | Experiences During the COVID-19 Pandemic: A Survey of Biosafety Professionals. | Biosafety professionals were called to action during the COVID-19 pandemic. They were tasked with prescribing measures to keep workers and munity safe while often not having accurate information at their fingertips. Understanding biosafety professionals' experiences may help shape new approaches that could further adva... |
36196095 | Biosafety Practices When Working with Bats: A Guide to Field Research Considerations. | Field work with bats is an important contribution to many areas of research in environmental biology and ecology, as well as microbiology. Work with bats poses hazards such as bites and scratches, and the potential for exposure to infectious pathogens such as rabies virus. It also exposes researchers to many other pote... |
36196096 | Aerosolised micro and nanoparticle: formulation and delivery method for lung imaging. | The application of contrast and tracing agents is essential for lung imaging, as indicated by the wide use in recent decades and the discovery of various new contrast and tracing agents. Different aerosol production and pulmonary administration methods have been developed to improve lung imaging quality. This review de... |
36196097 | Trauma Ultrasound Training for Latin American Countries. | The Pan-American Trauma Society (PTS) developed a Trauma and Emergency Ultrasound Course (USET) in response to the requirement for trauma ultrasound training for low-and e countries. The objective of this study was to evaluate the efficiency of this course. |
36196099 | Recovering Rare Earth Elements from Coal Mine Drainage Using Industrial Byproducts: Environmental and Economic Consequences. | Coal mine drainage (CMD) impairs tens of thousands of kilometers of U.S. waterways each year, in part with the leaching of low concentrations of rare earth elements (REEs). REEs are essential for modern technologies, yet economically viable natural deposits are geospatially limited, thus engendering geopolitical concer... |
36196098 | A Path Toward Systemic Equity in Life Cycle Assessment and Decision-Making: Standardizing Sociodemographic Data Practices. | Social equity has been a concept of interest for many years, gaining increased focus from energy and munities. The equitable development, collection, and reporting of sociodemographic data (e.g., data related to socioeconomic status, race, and ethnicity) are needed to help meet several of the United Nations Sustainable... |
36196100 | Healthcare Access Among Individuals of Asian Descent in the U.S. | Some groups of Asian Americans, especially Asian Indians, experience higher rates of atherosclerotic cardiovascular disease pared with other groups in the U.S. Barriers in accessing medical care partly may explain this higher risk as a result of delayed screening for cardiovascular risk factors and timely initiation of... |
36196101 | A Multi-Site Survey Study of Patient Satisfaction with Teledermatology. | Telemedicine has been of heightened focus due to spikes in usage during the COVID-19 pandemic. Disparities in health care may affect patient satisfaction with this resource depending on factors such as patient race, age, or socioeconomic background. The purpose of this study was to analyze patient satisfaction with tel... |
36196103 | The Influence of the STORM Program and Other Elective Experiences During the Summer Between the First and Second Year on Medical Students' Career Interests. | The purpose of this study was to investigate the influence of the Summer Training Option in Rural Medicine (STORM) program and other elective experiences during the summer between the first and second pre-clerkship years of medical school on medical students' career intentions. |
36196102 | Millennials Seeking Healthcare: Examining the Degree to Which Patients Utilize Online Resources. | According to the 2020 U.S. Census, a Silver Tsunami is looming, with more than 75.4 million persons aged 57 to 75 expected to need more costly medical care. However, a larger wave of 83.1 million Millennials nearing adulthood is approaching rapidly. Therefore, it is important to understand how this population finds the... |
36196104 | Clinical Rotation Handbook Promotes Orthopaedic Resident Wellness: A Quality Improvement Study. | Transitioning from one clinical rotation to the next may be particularly stressful for orthopaedic residents attempting to navigate new work environments with new faculty mentors and new patients. The purpose of this quality improvement (QI) project was to determine if resident stress could be improved by using a handb... |
36196105 | A Measure of Burnout in Current NCAA Student-Athletes. | The prevalence of athletes who specialize in sports has increased in recent years. Substantial literature on youth sports has linked early sport specialization to negative consequences, such as burnout and injury. However, empirical paring rates of burnout and specialization in NCAA athletes is limited. The purpose of ... |
36196106 | Birth Outcomes Related to Distance in Rural and Frontier Kansas. | Women from munities must travel greater distances to secure obstetrical care. This study sought the extent to which distance traveled by mothers for obstetrical services affects birth es in rural and frontier counties of Kansas. |
36196107 | Lessons Learned from Implementing Unconscious Bias Training at an Academic Medical Center. | In 2018, our Midwestern university medical center began offering unconscious bias training. Each session concluded with a standard evaluation. We analyzed two years of data that focused on three areas: 1) whether demographic differences or amount of prior knowledge on the topic influenced the training experience; 2) wh... |
36196110 | Recent progress on BFT in the era of blockchains. | This perspective highlights some recent progress on the research of Byzantine fault tolerant (BFT) consensus protocol in the era of blockchains, including both partially synchronous BFT and asynchronous BFT protocols, their fundamental building blocks, and their variants. |
36196109 | Beginning: China's national park system. | At the leaders' summit of the 15th Meeting of the Conference of the Parties to the Convention on Biological Diversity (COP15) on 12 October 2021, China's President Xi Jinping declared that China has officially designated its first group of national parks-the Three-River-Source National Park, the Giant Panda National Pa... |
36196112 | Decoupling engineering of formamidinium-cesium perovskites for efficient photovoltaics. | Although pure formamidinium iodide perovskite (FAPbI |
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