Pubmed Text
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Collection of pubmed 2024 papers. • 11 items • Updated
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36408220 | Non-covalent cyclic peptides simultaneously targeting Mpro and NRP1 are highly effective against Omicron BA.2.75. | Available vaccine-based immunity may at high risk of being evaded due to substantial mutations in the variant Omicron. The main protease (Mpro) of SARS-CoV-2 and human neuropilin-1 (NRP1), two less mutable proteins, have been reported to be crucial for SARS-CoV-2 replication and entry into host cells, respectively. The... |
36408222 | Supercritical fluid extract of | Oxaliplatin-based chemotherapy regimens are mended for patients with advanced colorectal cancer (CRC). However, oxaliplatin (OXA) can cause toxic side effects at the mended dosage. Therefore, it is necessary to find new drug candidates that can synergize with OXA and thereby lower the OXA dose while still maintaining i... |
36408221 | Cellular phenotypic transitions in diabetic nephropathy: An update. | Diabetic nephropathy (DN) is a major cause of morbidity and mortality in diabetes and is the mon cause of end stage renal disease (ESRD). Renal fibrosis is the final pathological change in DN. It is widely believed that cellular phenotypic switching is the cause of renal fibrosis in diabetic nephropathy. Several types ... |
36408224 | ECM1 regulates the resistance of colorectal cancer to 5-FU treatment by modulating apoptotic cell death and epithelial-mesenchymal transition induction. | 5-Fluorouracil (5-FU) chemoresistance is a persistent impediment to the efficient treatment of many types of cancer, yet the molecular mechanisms underlying such resistance remain pletely understood. Here we found CRC patients resistant to 5-FU treatment exhibited increased extracellular matrix protein 1 (ECM1) pared t... |
36408226 | Corrigendum: A Chinese medicine formula (kunbixiao granule) for female rheumatoid arthritis: Study protocol for a double-blind, randomized, placebo-controlled trial. | [This corrects the article DOI: 10.3389/fphar.2022.945565.]. |
36408228 | Anticholinesterase activity of | For many years, the primary focus has been on finding effective treatments for Alzheimer's disease (AD), which has led to the identification of promising therapeutic targets. The necessity for AD stage-dependent optimal settings necessitated a herbal therapy strategy. The plant species |
36408229 | A bibliometrics and visualization analysis of cannabidiol research from 2004 to 2021. | Cannabidiol, a ponent extracted from the plant cannabis sativa, has gained growing focus in recent years since its extensive pharmacology effects have been founded. The purpose of this study intends to reveal the hot spots and frontiers of cannabidiol research using bibliometrics and data visualization methods. A total... |
36408231 | Corrigendum: Adenosine receptor stimulation improves glucocorticoid-induced osteoporosis in a rat model. | [This corrects the article DOI: 10.3389/fphar.2017.00558.]. |
36408232 | Mitochondrial toxicity evaluation of traditional Chinese medicine injections with a dual | There are technical obstacles in the safety evaluation of traditional Chinese medicine (TCM) injections due to plex chemical nature and the lack of rapid and accurate |
36408230 | Ferroptosis: A new therapeutic target for bladder cancer. | Bladder cancer (BC) is the most frequent type of urinary system cancer. The prognosis of BC is poor due to high metastasis rates and multidrug resistance. Hence, development of novel therapies targeting BC cell death is urgently needed. As a novel cell death type with strong antitumor potential, ferroptosis has been in... |
36408237 | Corrigendum: Activation of A2A receptor by PDRN reduces neuronal damage and stimulates WNT/β-catenin driven neurogenesis in spinal cord injury. | [This corrects the article DOI: 10.3389/fphar.2018.00506.]. |
36408234 | Diagnostic and therapeutic strategies for non-alcoholic fatty liver disease. | The global incidence rate of non-alcoholic fatty liver disease (NAFLD) is approximately 25%. With the global increase in obesity and its associated metabolic syndromes, NAFLD has e an important cause of chronic liver disease in many countries. Despite recent advances in pathogenesis, diagnosis, and therapeutics, there ... |
36408240 | Sodium cantharidate promotes autophagy in breast cancer cells by inhibiting the PI3K-Akt-mTOR signaling pathway. | Sodium cantharidate (SCA) is a derivative of cantharidin obtained by its reaction with alkali. Studies have shown that it inhibits the occurrence and progression of several cancers. However, therapeutic effects of SCA on breast cancer are less well studied. This study aimed to clarify the effect of SCA on breast cancer... |
36408239 | Eupatilin attenuates the senescence of nucleus pulposus cells and mitigates intervertebral disc degeneration | Intervertebral disc degeneration (IDD) is the main cause of low back pain. An increasing number of studies have suggested that inflammatory response or the senescence of nucleus pulposus (NP) cells is strongly associated with the progress of IDD. Eupatilin, the main flavonoid extracted from |
36408236 | Glia from the central and peripheral nervous system are differentially affected by paclitaxel chemotherapy | Glia are critical players in defining synaptic contacts and maintaining neuronal homeostasis. Both astrocytes as glia of the central nervous system (CNS), as well as satellite glial cells (SGC) as glia of the peripheral nervous system (PNS), intimately interact with microglia, especially under pathological conditions w... |
36408241 | Necrotic-like BV-2 microglial cell death due to methylmercury exposure. | Methylmercury (MeHg) is a dangerous environmental contaminant with strong bioaccumulation in the food chain and neurotoxic properties. In the nervous system, MeHg may cause neurodevelopment impairment and potentially interfere with immune promising proper control of neuroinflammation and aggravating neurodegeneration. ... |
36408242 | Mechanism of interventional effect and targets of Zhuyu pill in regulating and suppressing colitis and cholestasis. | Zhuyu pill (ZYP) is a traditional Chinese medicine posed of two drugs, |
36408245 | Screening for effective cell-penetrating peptides with minimal impact on epithelial cells and gut commensals | One of the biggest challenges for oral drug absorption is the epithelial barrier of the gastrointestinal tract. The use of cell-penetrating peptides (CPPs) to modulate the epithelial barrier function is known to be an effective strategy to improve drug absorption and bioavailability. In this study pare side-by-side, 9 ... |
36408246 | Dysregulated hepatic UDP-glucuronosyltransferases and flavonoids glucuronidation in experimental colitis. | Glucuronidation catalyzed by UDP-glucuronosyltransferases (UGTs) is one of the most important phase II mechanisms, facilitating drug clearance |
36408247 | Forsythiaside B ameliorates coagulopathies in a rat model of sepsis through inhibition of the formation of PAD4-dependent neutrophil extracellular traps. | Forsythiaside B (FTB) is one of the ponents of |
36408251 | Pathological complete remission of a locally advanced gastric cancer by neoadjuvant therapy "sandwich" regimen as SOXAP+ fluorescence laparoscopic surgery +SOXAP: Case report. | Gastric cancer is an extremely burdensome and challenging malignant tumor with a high incidence and a high mortality rate, which seriously results in a thorny prognosis for oncology patients. Surgical bined with postoperative adjuvant therapy are currently the most regular methods for the treatment of locally advanced ... |
36408244 | SIRT1 activation and its effect on intercalated disc proteins as a way to reduce doxorubicin cardiotoxicity. | According to the World Health Organization, the neoplasm is one of the main reasons for morbidity and mortality worldwide. At the same time, application of cytostatic drugs like an independent type of cancer treatment and bination with surgical methods, is often associated with the development of plications both in the... |
36408249 | The therapeutic potential of natural products for treating pancreatic cancer. | Pancreatic cancer is one of the most malignant tumors of the digestive tract, with the poor prognosis and low 5-year survival rate less than 10%. Although surgical resection and chemotherapy as gemcitabine (first-line treatment) has been applied to the pancreatic cancer patients, the overall survival rates of pancreati... |
36408252 | Substrate stiffness engineered to replicate disease conditions influence senescence and fibrotic responses in primary lung fibroblasts. | In fibrosis remodelling of ECM leads to changes position and stiffness. Such changes can have a major impact on cell functions including proliferation, secretory profile and differentiation. Several studies have reported that fibrosis is characterised by increased senescence and accumulating evidence suggests that chan... |
36408255 | Therapeutic mechanism and clinical application of Chinese herbal medicine against diabetic kidney disease. | Diabetic kidney disease (DKD) is the plications of type 1 and 2 diabetes, and is the predominant cause of chronic kidney disease and end-stage renal disease. The treatment of DKD normally consists of controlling blood glucose and improving kidney function. The blockade of renin-angiotensin-aldosterone system and the in... |
36408258 | Mechanisms of sympathoexcitation | Many drugs used in cardiovascular therapy, such as angiotensin receptor antagonists and beta-blockers, may exert at least some of their actions through effects on the sympathetic nervous system, and this also holds true for e.g., P2Y |
36408256 | Cpd-42 protects against calcium oxalate nephrocalcinosis-induced renal injury and inflammation by targeting RIPK3-mediated necroptosis. | Calcium oxalate (CaOx) crystals, as the ponent of human kidney stones, can trigger excessive cell death and inflammation of renal tubular epithelial cells, involved in the pathogenesis of nephrocalcinosis. Necroptosis mediated by receptor-interacting protein kinase 3 (RIPK3) serves a critical role in the cytotoxicity o... |
36408260 | Berbamine inhibits RANKL- and M-CSF-mediated osteoclastogenesis and alleviates ovariectomy-induced bone loss. | Osteoporosis is mon public health problem characterized by decreased bone mass, increased bone brittleness and damage to the bone microstructure. Excessive bone resorption by osteoclasts is the main target of the currently used drugs or treatment for osteoporosis. Effective antiresorptive drugs without side effects fol... |
36408261 | Baicalin regulates stem cells as a creative point in the treatment of climacteric syndrome. | It is widely acknowledged that the climacteric syndrome negatively affects women's quality of life and leads to cerebral ischemic injury, osteoporosis and cardiovascular disease. One of the main active ingredients in Radix Scutellariae, Baicalin, has been established to possess a wide range of pharmacological effects a... |
36408264 | Norcantharidin ameliorates estrogen deficient-mediated bone loss by attenuating the activation of extracellular signal-regulated kinase/ROS/NLRP3 inflammasome signaling. | Osteoporosis, characterized by reduced bone mass, aberrant bone architecture, and elevated bone fragility, is driven by a disruption of bone homeostasis between bone resorption and bone formation. However, up to now, no drugs are perfect for osteoporosis treatment due to different defects. In this study, we demonstrate... |
36408266 | Effect of drying methods on yield, physicochemical properties, and total polyphenol content of chamomile extract powder. | Chamomile ( |
36408274 | Mangiferin promotes osteogenic differentiation and alleviates osteoporosis in the ovariectomized mouse | Mangiferin is a xanthone glucoside extracted from multiple plants, which has been shown to inhibit bone resorption and alleviate osteoporosis. However, the effect of purified Mangiferin on osteoporosis and its specific mechanisms is unknown. This study aimed to explore whether Mangiferin can promote osteogenic differen... |
36408273 | Relationship between miRNA and ferroptosis in tumors. | Malignant tumor is a major killer that seriously endangers human health. At present, the methods of treating tumors include surgical resection, chemotherapy, radiotherapy and immunotherapy. However, the survival rate of patients is still very low due to plicated mechanism of tumor occurrence and development and high re... |
36408275 | The benefits of propofol on cancer treatment: Decipher its modulation code to immunocytes. | Anesthetics are essential for cancer surgery, but accumulated research have proven that some anesthetics promote the occurrence of certain cancers, leading to adverse effects in the lives of patients. Although anesthetic technology is mature, there is no golden drug selection standard for surgical cancer treatment. To ... |
36408276 | First-in-human study to investigate the safety and pharmacokinetics of salvianolic acid A and pharmacokinetic simulation using a physiologically based pharmacokinetic model. | Salvianolic acid A (SAA) is a water-soluble phenolic ponent from |
36408277 | Doxycycline Hydrochloride Regulates Cytoskeletal Rearrangement and Epithelial-To-Mesenchymal Transition in Malignant Rhabdoid Tumour of the Kidney. | As a highly malignant tumour, malignant rhabdoid tumours of the kidney (MRTK) are prone to metastasis and invasion, while tumour metastasis and invasion are inseparable from matrix metalloproteinases (MMPs) and epithelial-mesenchymal transformation (EMT). Moreover, the key to EMT is remodelling of the cytoskeleton. The... |
36408278 | Baicalin Mitigates the Neuroinflammation through the TLR4/MyD88/NF- | Baicalin (BA) is a major flavone from |
36408279 | Antidepressant Active Components of Bupleurum chinense DC-Paeonia lactiflora Pall Herb Pair: Pharmacological Mechanisms. | Depression is a serious psychological disorder with a rapidly increasing incidence in recent years. Clinically, selective serotonin reuptake inhibitors are the main therapy. These drugs, have serious adverse reactions, however. Traditional Chinese medicine has the characteristics of ponents, targets, and pathways, whic... |
36408280 | Single-Cell Gene Expression Analysis in Patients with Medullary Sponge Kidney and a Retrospective Study. | To establish better diagnosis thinking and provide advanced understanding of MSK, the CT imaging features, clinical characteristics, and the expression of suspected genes in the kidney spatiotemporal immune zonation and fetal renal development were investigated. |
36408281 | The Prescription of Oral Mucosal Mesenchymal Stem Cells post-Traumatic Brain Injury Improved the Kidney and Heart Inflammation and Oxidative Stress. | In the last years, mesenchymal stem cells (MSCs) have been considered as a useful strategy to treat many diseases such as traumatic brain injury (TBI). The production of inflammatory agents by TBI elicits an inflammatory response directed to other systems of body, such as the heart and the kidneys. In this study, the e... |
36408283 | Cross-Breeding Improvement and Performance Analysis of Dominant Production Traits in Grazing-Type Alfalfa ( | Rhizome-rooted |
36408284 | Noninvasive Approach of | Accurate, cost-effective, and noninvasive alternative molecular methods are needed for detecting low malaria parasitemia. The currently-used nested polymerase chain reaction (nPCR) requires blood as well as skilled personnel in order to minimise the risk of bloodborne disease transmission. Therefore, this study is aime... |
36408286 | Framework for detection of probable clues to predict misleading information proliferated during COVID-19 outbreak. | Spreading of misleading information on social web platforms has fuelled huge panic and confusion among the public regarding the Corona disease, the detection of which is of paramount importance. To identify the credibility of the posted claim, we have analyzed possible evidence from the news articles in the google sear... |
36408287 | A transformer fine-tuning strategy for text dialect identification. | Online medical consultation can significantly improve the efficiency of primary health care. Recently, many online medical question-answer services have been developed that connect the patients with relevant medical consultants based on their questions. Considering the linguistic variety in their question, social backg... |
36408289 | Academic performance warning system based on data driven for higher education. | Academic probation at universities has e a matter of pressing concern in recent years, as many students face severe consequences of academic probation. We carried out research to find solutions to decrease the situation mentioned above. Our research used the power of massive data sources from the education sector and t... |
36408288 | Novel favipiravir pattern-based learning model for automated detection of specific language impairment disorder using vowels. | Specific language impairment (SLI) is one of the mon diseases in children, and early diagnosis can help to obtain better timely therapy economically. It is difficult and time-consuming for clinicians to accurately detect SLI through standard clinical assessments. Hence, machine learning algorithms have been developed t... |
36408290 | Enhanced Ali Baba and the forty thieves algorithm for feature selection. | Feature Selection (FS) aims to ameliorate the classification rate of dataset models by selecting only a small set of appropriate features from the initial range of features. In consequence, a reliable optimization method is needed to deal with the matters involved in this problem. Often, traditional methods fail to opt... |
36408293 | The genome sequence of the orange-tip butterfly, | We present a genome assembly from an individual female |
36408294 | SARS-CoV-2 and monkeypox: what is common and what is not in a present pandemic versus a potential one-a neuropsychiatric narrative review. | Pandemic represents challenging medical emergency as it is usually associated with high rates of mortalities and morbidities. Along the last 2 and half years the world has faced the emergence of severe acute respiratory syndrome corona virus 2 pandemic that caught medical agencies and health authorities by surprise and... |
36408297 | Current Approaches for Image Fusion of Histological Data with Computed Tomography and Magnetic Resonance Imaging. | Classical analysis of biological samples requires the destruction of the tissue's integrity by cutting or grinding it down to thin slices for (Immuno)-histochemical staining and microscopic analysis. Despite high specificity, encoded in the stained 2D section of the whole tissue, the structural information, especially ... |
36408298 | Understanding Factors that Shape Exposure to Zoonotic and Food-Borne Diseases Across Wild Meat Trade Chains. | The rise of zoonotic disease-related public health crises has sparked calls for policy action, including calls to close wildlife markets. Yet, these calls often reflect limited understanding of where, precisely, exposure to risk occurs along wildlife and wild meat trade chains. They also threaten to negatively impact f... |
36408299 | The transition from school to university in mathematics education research: new trends and ideas from a systematic literature review. | Investigating the transition between educational levels is one of the main themes for the future of mathematics education. In particular, the transition from secondary school to STEM degrees is problematic for the widespread students' difficulties and significant for the implications that it has on students' futures. K... |
36408300 | The Rate of Appendicular Neoplasm in Patients Who Underwent Appendectomy for Acute Appendicitis at King Abdulaziz Medical City, Riyadh. | Background Appendicitis is mon reason for hospitalization. Rarely do people with acute appendicitis have an appendiceal mass called an abscesses or inflamed phlegmon. The goal of this study was to determine the prevalence of different appendiceal tumors including neuroendocrine tumors, adenocarcinoma, carcinoid, and mu... |
36408301 | The Relationship Between Access to Abortion and Mental Health in Women of Childbearing Age: Analyses of Data From the Global Burden of Disease Studies. | Background It has often been suggested that restricting access to legal abortion could have a negative impact on the mental health of women seeking this procedure. The recent judgment of the United States Supreme Court in the Dobbs case has brought the question of the psychological impact of changes in abortion policy ... |
36408302 | Impact of Intrauterine Growth Restriction and Placental Insufficiency on Nutritional Outcomes of Extremely Low Birth Weight Infants. | Introduction The aim of our study was to assess the impact of intrauterine growth restriction (IUGR) and placental insufficiency (PI) on the nutritional es of extremely low birth weight (ELBW) infants. Methods We conducted a six-year retrospective case-control study that included 117 ELBW infants. Of these, 58 infants ... |
36408303 | Spinal Gunshot Wound With an Air Rifle: A Case Report. | Spinal gunshot injuries are one of the most serious injuries that can cause morbidity and mortality. We report a case of a nine-year-old boy, referred to our emergency department from another hospital, with lower limb weakness after being shot by an air gun in his back. After extensive investigation, it appeared that a... |
36408304 | The Importance of Radiologic Imaging Modalities in Autosomal Dominant Polycystic Kidney Disease. | Autosomal dominant polycystic kidney disease (ADPKD) is mon disorder that occurs in approximately one in 1000 live births. Patients may be asymptomatic or present with symptoms such as hypertension, hematuria, proteinuria, or renal function impairment. It can present with extra plications like cerebral aneurysms, hepat... |
36408305 | Mesenteric Vasculitis and Urinary System Involvement Presenting As the Initial Manifestations of Systemic Lupus Erythematosus Treated Successfully With Glucocorticoids and Rituximab: A Case Report. | We describe a case of systemic lupus erythematosus (SLE) presenting initially with mesenteric vasculitis and urinary system involvement without any other SLE clinical features and a weakly positive antinuclear antibody on initial testing. She is a 15-year-old healthy female who presented with severe abdominal pain, dia... |
36408306 | Determining the Occurrence of Hypothyroidism Following Treatment With Radiation Therapy in Head and Neck Carcinoma Patients and the Associated Role of Risk Factors and Dose-Volume Histograms: A Prospective Study. | Background Head and neck carcinomas are one of the mon malignancies in developing countries including India. Most patients are treated with radiotherapy. Although post-radiotherapy hypothyroidism is a plication, data regarding its incidence and factors influencing it are scarce. This study aimed to determine the incide... |
36408307 | Risperidone Abruption-Induced Tardive Dyskinesia in a Six-Year-Old Male Patient With Known Autism and Attention Deficit Hyperactivity Disorder: A Case Report. | As a serotonin-dopamine antagonist, risperidone is less likely than traditional antipsychotics to result in tardive dyskinesia (TD). There are not many reports of risperidone abruption-induced TD. Herein we report a new case of tardive dyskinesia induced by a sudden stop of risperidone during the treatment of an autist... |
36408308 | Prevalence and Radiological Characteristics of the Fabella in Turkish Population. | This study aimed to evaluate and analyze the prevalence and radiological characteristics of the fabella in the Turkish population, detecting differences between genders by examining magnetic resonance imaging (MRI) images of subjects. |
36408309 | Effect of Weather Conditions on the Pediatric Supracondylar Humerus Fracture Incidence. | Some environmental factors pose as risk factors for children's supracondylar humerus fractures. This study aimed to evaluate the relationship between weather conditions and pediatric supracondylar humerus fracture incidence. |
36408310 | Falling Trend in the Epidemiology of Gastric Cancer in Mississippi From 2003 to 2019: What Mississippi Got Right. | The aim of this study is to give insight into the falling trend in gastric cancer epidemiology in the state of Mississippi. The period in focus is between 2003 and 2019. The aim of this study is to uncover what the state got right and the implications for future healthcare. |
36408311 | Open Subpectoral Tenodesis for Isolated Traumatic Long Head of Biceps Tendon Rupture Provides Excellent Functional Outcomes in Active Male Patients. | For many years the long head of biceps tendon (LHBT) rupture has been described and monly identified by weakness, cramping, and the so-called "Popeye" sign. Traditionally, this was treated non-operatively, likely reflecting patient factors and the technical difficulty in reattaching a degenerative and shortened tendon... |
36408312 | Association of Glycosylated Haemoglobin (HbA1c) Level With Left Ventricular Diastolic Dysfunction in Patients With Type 2 Diabetes. | Background Some literature has shown a high prevalence of pre-clinical diastolic dysfunction in subjects with type 2 diabetes mellitus. The current study was carried out to determine the association of glycosylated hemoglobin (HbA1c) levels with left ventricular diastolic dysfunction (LVDD) in patients with type 2 diab... |
36408313 | Patient Satisfaction With Primary Healthcare Services in Al-Ahsa, Saudi Arabia. | Background Patient satisfaction is regarded as a valid and significant indicator of the quality of medical care delivered. Additionally, it has been shown to be linked to better health es. The goal of the study is to assess patients' overall satisfaction regarding primary healthcare (PHC) services. Methodology In this ... |
36408314 | Geographical Distribution of Pancreatic Cancer in the State of Mississippi by Incidence and Mortality From 2003 to 2019. | Pancreatic cancer can be a very debilitating disease. In the USA and around the world, pancreatic cancer is among the causes of cancer-related deaths. This study aims to highlight mortality and incidence rates of pancreatic cancer by geographic location. |
36408315 | Cardiac Rehabilitation and Cardiopulmonary Fitness in Children and Young Adults With Congenital Heart Diseases: A Critically Appraised Topic. | Public health guidelines and a myriad of studies have proven that exercise is beneficial in the alleviation of various cardio-metabolic diseases. Congenital heart disease (ConHD) is one of the most frequently occurring congenital structural malfunctions in the pediatric population, affecting nine of every 1,000 live bi... |
36408316 | Bitten to the Bone: A Case of Anxiety-Induced Osteomyelitis. | Onychophagia is a habitual nail-biting disorder, usually associated with mental or emotional diseases. It affects 20-30% of the population in all age groups. Human bites have the potential to e serious injuries due to high virulence in the human oral flora and may often require hospital admission, antibiotics and even ... |
36408317 | The origin and distribution of 'Kokubu'-type splice-site mutations of the | The Japanese domestic tobacco ( |
36408318 | Developing core marker sets for effective genomic-assisted selection in wheat and barley breeding programs. | Wheat ( |
36408319 | Genetic variation and genetic control of intraspikelet differences in grain weight and seed dormancy in wild and domesticated emmer wheats. | Seed dormancy, a vital strategy for wild plant species to adapt to an unpredictable environment in their natural habitats, was eliminated from cereals during the domestication process. Intraspikelet differences in grain size and seed dormancy have been observed in wild emmer wheat. To elucidate the genetic variation of... |
36408320 | Hybridization with | Compared mon buckwheat ( |
36408321 | Quantitative trait loci (QTL) for low temperature tolerance at the young microspore stage in rice ( | Low temperatures at the young microspore stage (YMS) decreases spikelet fertility and is a major limiting factor to rice production in temperate Australia. Low temperature tolerance is a difficult trait to phenotype, hence there is a strong desire for the identification of quantitative trait loci (QTL) for their use in... |
36408322 | Identification of a unique allele in the quantitative trait locus for crown root number in | To explore the genetic resources that could be utilized to help improve root system architecture phenotypes in rice ( |
36408323 | Transferring of clubroot-resistant locus | Clubroot, caused by |
36408324 | Erratum: Development of diagnostic molecular markers for marker-assisted breeding against bacterial wilt in tomato. | [This corrects the article DOI: 10.1270/jsbbs.20027.]. |
36408327 | Mosque as a COVID-19 vaccination site in collaboration with a private clinic: A short report from Osaka, Japan. | Ethnic minorities are vulnerable to disasters, including the COVID-19 pandemic. Vaccination strategies that do not leave ethnic minorities behind are required. This is a report on the use of Osaka Islamic Center, a mosque, as a group vaccination site for an ethnic minority group in Osaka, Japan, from August to Septembe... |
36408328 | Sodium Tanshinone IIA Sulfonate Inhibits Vascular Endothelial Cell Pyroptosis via the AMPK Signaling Pathway in Atherosclerosis. | Atherosclerosis (AS) is the underlying cause of cardiovascular events. Endothelial cell mitochondrial damage and pyroptosis are important factors contributing to AS. Changes in internal mitochondrial conformation and increase in reactive oxygen species (ROS) lead to the disruption of mitochondrial energy metabolism, ac... |
36408329 | Using attack graphs to defend healthcare systems from cyberattacks: a longitudinal empirical study. | Cyber security passes a variety of financial, political, and social aspects with significant implications for the safety of individuals and organisations. Hospitals are among the least secure and most vulnerable organisations in terms of cybersecurity. Protecting medical records from cyberattacks is critical for protec... |
36408330 | Significance of voiced and unvoiced speech segments for the detection of common cold. | This work investigates the significance of the voiced and unvoiced region for mon cold from the speech signal. In literature, the entire speech signal is processed to detect mon cold and other diseases. This study uses a short-time energy-based approach to segment the voiced and unvoiced region of the speech signal. Th... |
36408331 | A transcriptome-Based Deep Neural Network Classifier for Identifying the Site of Origin in Mucinous Cancer. | There is a lack of tools for identifying the site of origin in mucinous cancer. This study aimed to evaluate the performance of a transcriptome-based classifier for identifying the site of origin in mucinous cancer. |
36408332 | A Study to Improve the Vitamin A and Iodine Status of Pregnant Women through a Multiple Micronutrient Fortified Salt. | To study the efficacy of a multiple micronutrient fortified salt enriched with iron, iodine, vitamin A, vitamin B1, vitamin B2, vitamin B6, vitamin B12, niacin, and folic acid in improving serum retinol and iodine status of pregnant women. |
36408333 | Proximity of Water Wells to Public Water Testing Facilities in Alberta Using Drive Times. | Approximately 10% of Albertans rely on well water for domestic purposes. The responsibility of water testing and stewardship is left to private well owners. Few well water owners conduct routine testing of their well water supplies. Drive times to public water testing facilities may be an important factor limiting a we... |
36408334 | Radiological Dose Assessment due to the Presence of Norms in the Top Soil of the Imo State Polytechnic, Imo State Nigeria. | A study on the radiological dose assessment due to the presence of natural radionuclides in the top soil of Imo state Polytechnic was carried out using a gamma spectroscopic method. From the activity concentrations of natural radionuclides in the topsoil, the absorbed dose rate and annual effects of doses were establis... |
36408335 | Real-World Data of Trifluridine/Tipiracil for Patients With Advanced Gastric Cancer: A Multi-Institutional Retrospective Study. | A trial with trifluridine/tipiracil (FTD/TPI) versus placebo in patients with heavily pretreated metastatic gastric cancer showed that FTD/TPI is effective with manageable toxicity in these patients. However, real-world data on the effects of FTD/TPI in patients with advanced gastric cancer (AGC) are limited. |
36408336 | Combination of Baseline and Variation of Prognostic Nutritional Index Enhances the Survival Predictive Value of Patients With Advanced Non-Small Cell Lung Cancer Treated With Programmed Cell Death Protein 1 Inhibitor. | Low baseline prognostic nutritional index (PNI) scores are associated with poor survival for various malignancies; however, they vary based on the cohort and time resulting in inaccurate results. We determined the predictive value of the PNI score variations in addition to the baseline PNI scores for patients with adva... |
36408337 | Feasibility and value of salivary cortisol sampling to reflect distress in head and neck cancer patients undergoing chemoradiation: A proof-of-concept study. | Head and neck cancer (HNC) patients undergoing monly experience severe and persistent distress associated with treatment related fear and physical side effects such as xerostomia, dysphagia, and dryness of mouth. Cortisol, a stress sensitive hormone, can be easily measured in saliva to reflect biobehavioral responses t... |
36408341 | Knockdown of lncRNA | Increasing studies reported that long noncoding RNAs are involved in regulating glioma progression. However, the specific roles and mechanisms of lncRNAs in glioma remain unclear. Here, we sought to explore the functions of HOXD-AS2 in glioma progression. |
36408343 | Neutrophils: As a Key Bridge between Inflammation and Thrombosis. | Immunothrombosis is a mechanism of defense of the organism against pathogenic microorganisms that increases their recognition, limitation, and clearance and is part of the innate immune defense. Physiological immunothrombosis is beneficial to the body against the invasion of pathogenic microorganisms, but when immunoth... |
36408344 | Inhibitory Effects of | Esophageal squamous cell carcinoma (ESCC) is one of the most frequently occurring diseases in the world. |
36408345 | Multidimensional Pain Modulation by Acupuncture Analgesia: The Reward Effect of Acupuncture on Pain Relief. | Pain is an intrinsically unpleasant experience with features that protect an organism by promoting motivation and learning. Pain relief, a negative reinforcement of pain, is considered a reward and activates the brain's reward system. The reward circuit in the brain involves reward and pain. Acupuncture has a multidime... |
36408346 | A Cohort Study of Surgical Indexes, Postoperative Complications, Recovery Speed, and Prognosis of Stanford Type A Aortic Dissection Compared with Traditional Sun's Operation. | The objective is to explore the surgical index, plications, recovery speed, and prognosis of Stanford type A aortic dissection pared with traditional 'Sun's operation. |
36408347 | Improvement, Validation, and Analysis of Colles Fracture Treated with an Integrated Retainer Pad Splint. | To observe the effectiveness and safety of the Colles fracture treated with the integrated retainer pad splint and pare the clinical and radiological es of the integrated retainer pad splint and the traditional bamboo curtain splint in the treatment of the Colles fracture. |
36408348 | Chronic Antihyperglycemic Effect Exerted by Traditional Extracts of Three Mexican Medicinal Plants. | Chronic hyperglycemia, the product of uncontrolled diabetes, leads to the appearance of plications that can result in the premature death of diabetic patients. Consequently, pharmacological intervention with hypoglycemic agents could delay plications and improve the quality of life of patients in the long term. Traditi... |
36408349 | Data curation to support toxicity assessments using the Integrated Chemical Environment. | Humans are exposed to large numbers of chemicals during their daily activities. To assess and understand potential health impacts of chemical exposure, investigators and regulators need access to reliable toxicity data. In particular, reliable toxicity data for a wide range of chemistries are needed to support developm... |
36408351 | Leading Change Together: Supporting Collaborative Practice through Joint Accreditation for Interprofessional Continuing Education. | Interprofessional continuing education in support of team-based care is a ponent of healthcare quality and safety. In an effort to develop and advance the field of interprofessional continuing education (IPCE), the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Ed... |
36408352 | Outcomes in ED patients with non-specific ECG findings and low high-sensitivity troponin. | Although some emergency department risk stratification tools consider non-specific ECG findings as an aid in disposition decisions, their clinical value in patients with an initially low high-sensitivity cardiac troponin I (hsTnI) is unclear. |
36408353 | COVID-19 vaccine controversy: A cross-sectional analysis of factors associated with COVID-19 vaccine acceptance amongst emergency department patients in New York City. | Understanding variables associated with coronavirus disease 2019 (COVID-19) vaccine confidence and hesitancy may inform strategies to improve vaccine uptake in clinical settings such as the emergency department (ED). We aim to identify factors contributing to COVID-19 vaccine acceptance and to assess patient attitudes ... |
36408354 | A new framework for polynomial approximation to differential equations. | In this paper, we discuss a framework for the polynomial approximation to the solution of initial value problems for differential equations. The framework is based on an expansion of the vector field along an orthonormal basis, and relies on perturbation results for the considered problem. Initially devised for the app... |