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OBJECTIVE: This retrospective chart review describes the epidemiology and clinical features of 40 patients with culture-proven Mycoplasma pneumoniae infections at King Abdulaziz University Hospital, Jeddah, Saudi Arabia. METHODS: Patients with positive M. pneumoniae cultures from respiratory specimens from January 1997...
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Inflammatory diseases of the respiratory tract are commonly associated with elevated production of nitric oxide (NO•) and increased indices of NO• -dependent oxidative stress. Although NO• is known to have anti-microbial, anti-inflammatory and anti-oxidant properties, various lines of evidence support the contribution ...
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Surfactant protein-D (SP-D) participates in the innate response to inhaled microorganisms and organic antigens, and contributes to immune and inflammatory regulation within the lung. SP-D is synthesized and secreted by alveolar and bronchiolar epithelial cells, but is also expressed by epithelial cells lining various e...
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Endothelin-1 (ET-1) is a 21 amino acid peptide with diverse biological activity that has been implicated in numerous diseases. ET-1 is a potent mitogen regulator of smooth muscle tone, and inflammatory mediator that may play a key role in diseases of the airways, pulmonary circulation, and inflammatory lung diseases, b...
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Respiratory syncytial virus (RSV) and pneumonia virus of mice (PVM) are viruses of the family Paramyxoviridae, subfamily pneumovirus, which cause clinically important respiratory infections in humans and rodents, respectively. The respiratory epithelial target cells respond to viral infection with specific alterations ...
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"Nidovirus subgenomic mRNAs contain a leader sequence derived from the 5′ end of the genome fused (...TRUNCATED)
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"Recent evidence suggests that critically ill patients are able to tolerate lower levels of haemoglo(...TRUNCATED)
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"The 21st International Symposium on Intensive Care and Emergency Medicine was dominated by the resu(...TRUNCATED)
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"Heme oxygenase-1 (HO-1), an inducible stress protein, confers cytoprotection against oxidative stre(...TRUNCATED)
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"This report describes the design and implementation of the Real-time Outbreak and Disease Surveilla(...TRUNCATED)
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