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Alterations of the architecture of cerebral white matter in the developing human brain can affect cortical development and result in functional disabilities. A line scan diffusion-weighted magnetic resonance imaging (MRI) sequence with diffusion tensor analysis was applied to measure the apparent diffusion coefficient,...
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Myelodysplastic syndromes (MDS) are age-dependent stem cell malignancies that share biological features of activated adaptive immune response and ineffective hematopoiesis. Here we report that myeloid-derived suppressor cells (MDSC), which are classically linked to immunosuppression, inflammation, and cancer, were mark...
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ID elements are short interspersed elements (SINEs) found in high copy number in many rodent genomes. BC1 RNA, an ID-related transcript, is derived from the single copy BC1 RNA gene. The BC1 RNA gene has been shown to be a master gene for ID element amplification in rodent genomes. ID elements are dispersed through a p...
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DNA methylation plays an important role in biological processes in human health and disease. Recent technological advances allow unbiased whole-genome DNA methylation (methylome) analysis to be carried out on human cells. Using whole-genome bisulfite sequencing at 24.7-fold coverage (12.3-fold per strand), we report a ...
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Two human Golli (for gene expressed in the oligodendrocyte lineage)-MBP (for myelin basic protein) cDNAs have been isolated from a human oligodendroglioma cell line. Analysis of these cDNAs has enabled us to determine the entire structure of the human Golli-MBP gene. The Golli-MBP gene, which encompasses the MBP transc...
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"Glioblastomas are deadly cancers that display a functional cellular hierarchy maintained by self-re(...TRUNCATED)
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[-0.3016093671321869,0.009211757220327854,0.06835313886404037,-0.0473826564848423,0.146259605884552,(...TRUNCATED)
"Realizing the full potential of human embryonic stem cells (hESCs) and induced pluripotent stem cel(...TRUNCATED)
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"BACKGROUND Microarrays offer great potential as a platform for molecular diagnostics, testing clini(...TRUNCATED)
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[0.4251996576786041,-0.019840635359287262,-0.08390570431947708,0.19412213563919067,0.078164964914321(...TRUNCATED)
"Summary. We consider the problem of comparing complex hierarchical models in which the number of pa(...TRUNCATED)
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"Likelihood ratios are one of the best measures of diagnostic accuracy, although they are seldom use(...TRUNCATED)
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