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Cattle tick control
['Bambara groundnut']
['Vigna subterranea']
['Tick-borne diseases']
['Boil 100g of Bambara groundnut in 1 liter of water for 15 minutes', "Strain the liquid and apply it to the cattle's skin"]
['Once a week for 4 weeks']
['15 minutes']
['Bambara groundnut is also used for human consumption, but the preparation for cattle is different']
Cattle tick control
['Lantana camara']
['Lantana camara']
['Tick-borne diseases']
['Boil 50g of Lantana camara leaves in 1 liter of water for 10 minutes', "Strain the liquid and apply it to the cattle's skin"]
['Once a week for 4 weeks']
['10 minutes']
['Lantana camara is a common weed that grows in the fields and is easily available']
Cattle tick control
['Moringa oleifera']
['Moringa oleifera']
['Tick-borne diseases']
['Boil 100g of Moringa oleifera leaves in 1 liter of water for 15 minutes', "Strain the liquid and apply it to the cattle's skin"]
['Once a week for 4 weeks']
['15 minutes']
['Moringa oleifera is a fast-growing plant that is commonly used for human consumption as well']
Cattle tick control
['Senna obtusifolia']
['Senna obtusifolia']
['Tick-borne diseases']
['Boil 50g of Senna obtusifolia leaves in 1 liter of water for 10 minutes', "Strain the liquid and apply it to the cattle's skin"]
['Once a week for 4 weeks']
['10 minutes']
['Senna obtusifolia is used for both human and animal medicinal purposes']
Cattle tick control
['Sorghum bicolor']
['Sorghum bicolor']
['Tick-borne diseases']
['Boil 100g of Sorghum bicolor grains in 1 liter of water for 15 minutes', "Strain the liquid and apply it to the cattle's skin"]
['Once a week for 4 weeks']
['15 minutes']
['Sorghum bicolor is a staple crop in the region and is used for human consumption']
Cattle treatment with plant species
['Moringa oleifera', 'Moringa oleifera', 'Moringa oleif:era', 'Moringa oleifera']
['Moringa oleifera', 'Moringa oleifera', 'Moringa oleifera', 'Moringa oleifera']
['Bacterial infection', 'Fungal infection', 'Parasitic infection', 'Viral infection']
null
['100g of fresh plant leaves, boiled in 1 liter of water for 10 minutes, and then cooled for 10 minutes', '100g of fresh plant leaves, boiled in 1 liter of water for 10 minutes, and then cooled for 10 minutes', '100g of fresh plant leaves, boiled in 1 liter of water for 10 minutes, and then cooled for 10 minutes', '100...
['5 minutes', '5 minutes', '5 minutes', '5 minutes']
['This is a common practice in the community', 'This is a common practice in the community', 'This is a common practice in the community', 'This is a common practice in the community']
banana beer
null
null
['east coast fever (Theileriosis)']
null
null
['VO.']
['roots of Carissa edulis, Acacia seyal, infusion']
pompo
null
null
['east coast fever (Theileriosis)']
null
null
['whole plant + roots']
['Oncoba spinosa, infusion']
lubilili
null
null
['cough', 'diarrhoea', 'measles']
null
null
['leaves of Vernonia amygdalina, Chenopodium opulifolium, Senna occidentalis, infusion, VO.']
['roots see Senna occidentalis and also Harrisonia abyssinica', 'leaves, infusion see also Chenopodium opulifolium']
mulugunyu
null
null
['east coast fever (Theileriosis)', 'measles']
null
null
['roots, infusion from Balanites aegyptiaca, Jatropha curcas, Gardenia ternifolia, VO. 500 ml once a day', 'roots, infusion from Balanites aegyptiaca + leaves of Chenopodium opulifolium and Cannabis sativa + salt, VO., 20l. in 4 days']
null
njaye
null
null
['east coast fever (Theileriosis)', 'measles']
null
null
['leaves decoction - - leaves infusion + roots Securidaca longipedunculata, VO. 125 ml / day']
['leaves see Chenopodium opu', 'Balanites aeg.', 'Lantana camara']
namuvu
null
null
['measles', 'cough']
null
null
['leaves infusion + salt, VO. 500 ml / day during 7 days', 'leaves of Chenopodium opulifolium, Cannabis sativa, Vernonia amygdalina + salt + powder soap of OMO, infusion, VO See also Balanites aeg. Lantana camara', 'leaves of Vernonia amygdalina, Chenopodium opulifolium, Senna']
null
diarrhoea
['Senna occidentalis']
null
['diarrhoea']
['leaves see Vernonia amygdal']
null
['leaves see Vernonia amygdal']
['leaves see Vernonia amygdal']
occidentalis, infusion, VO.
['Senna occidentalis']
null
['diarrhoea']
['leaves see Vernonia amygdal']
null
['leaves see Vernonia amygdal']
['leaves see Vernonia amygdal']
Clerodendrum myricoides
['mukuza nyana']
null
['east coast fever (Theileriosis)']
['Leaves infusion - - - see Albiziz coriaria']
null
null
null
Lantana camara
['kapanga']
null
['measles']
['leaves of Lantana camara, Chenopodium opulifolium, Cannabis sativa, VO., 125 ml']
null
null
null
Harinsonia abyssinica
['lushaike']
null
['east coast fever (Theileriosis)', 'diarrhoea']
['roots, infusion - - decoction + above ground part of Oxygonum sinuatum, VO. 200 ml, 3 X / day, during 5 days', 'roots of Harinsonia abyssinica, Vernonia amygdalina + salt, VO. 20 l']
null
null
null
Vernonia amygdalina
['kapanga']
null
['east coast fever (Theileriosis)', 'diarrhoea']
null
null
null
null
Clerodendrum myricoides
['mukuza nyana']
null
['east coast fever (Theileriosis)']
null
null
null
null
Lantana camara
['kapanga']
null
['measles']
null
null
null
null
Cancer treatment using traditional West African pharmacopeia
['Sesquiterpene', 'Other plants']
null
['Cancer', 'Inflammatory diseases', 'Infectious diseases', 'Skin diseases', 'Liver diseases', 'Lung diseases', 'Prostate diseases', 'Kidney diseases']
null
['Not specified', 'Not specified']
['Not specified', 'Not specified']
['The emergence of resistance to cancer chemotherapy has forced researchers to turn to natural products of plant and marine origin. In the West African sub-region, research on natural anti-cancer molecules is still in its infancy stage because of very limited financial resources and the scarcity of adequate technical f...
Malaria Treatment
['Moringa oleifera']
['Moringa oleifera']
['Malaria']
null
['Take 100 g of dried leaves of Moringa oleifera in 1 liter of water and boil for 10 minutes. Drink 1 cup (250 ml) of the decoction 3 times a day.']
['10 minutes']
['This recipe is based on traditional knowledge from the Moringa plant, which has been used in traditional medicine for malaria treatment.']
Antibacterial Treatment
['Neem']
['Azadirachta indica']
['Bacterial infections']
null
['Take 10 g of neem leaves in 1 liter of water and boil for 5 minutes. Drink 1 cup (250 ml) of the decoction 3 times a day.']
['5 minutes']
['Neem has been used in traditional medicine for antibacterial purposes.']
African Ginger
null
null
['cancer']
['Grind the fresh root of African ginger to a fine powder', 'Add 100g of the powder to 500ml of water', 'Boil for 15 minutes', 'Strain the liquid and take 100ml three times a day']
['Take 100ml three times a day']
['15 minutes']
['This recipe is used for internal consumption and is not recommended for external use', 'The recipe is not scientifically validated for cancer treatment', 'It is important to consult a healthcare professional before using this recipe']
Senna
null
null
['cancer']
['Boil 20g of dried senna leaves in 500ml of water for 15 minutes', 'Strain the liquid and take 100ml three times a day']
['Take 100ml three times a day']
['15 minutes']
['This recipe is used for internal consumption and is not recommended for external use', 'The recipe is not scientifically validated for cancer treatment', 'It is important to consult a healthcare professional before using this recipe']
Moringa
null
null
['cancer']
['Grind the leaves of moringa to a fine powder', 'Add 100g of the powder to 500ml of water', 'Boil for 10 minutes', 'Strain the liquid and take 100ml three times a day']
['Take 100ml three times a day']
['10 minutes']
['This recipe is used for internal consumption and is not recommended for external use', 'The recipe is not scientifically validated for cancer treatment', 'It is important to consult a healthcare professional before using this recipe']
Acacia macrostachya
['Acacia macrostachya']
['Acacia macrostachya (Mimosaceae)']
['Inflammation', 'Cancer']
null
['Decoction']
['10-15 minutes']
['Root barks are used']
Acalypha wilkesiana
['Acalypha wilkesiana']
['Acalypha wilkesiana (Euphorbiaceae)']
['Inflammation', 'Breast tumor']
null
['Concoction']
['10-15 minutes']
['Whole plant is used']
Aconthospermum hispidum
['Aconthospermum hispidum']
['Aconthospermum hispidum (Asteraceae)']
['Cancer']
null
['Poultice and decoction']
['10-15 minutes']
['Flowering shoots are used']
Annona senegalensis
['Annona senegalensis']
['Annona senegalensis (Annonaceae)']
['Skin cancer', 'Leukemia']
null
['Hydrodistillation']
['10-15 minutes']
['Stem barks and leaves are used']
Balanites aegyptiaca
['Balanites aegyptiaca']
['Balanites aegyptiaca (Balanitaceae)']
['Inflammation', 'Diabetes', 'Parasitic diseases']
null
['Aqueous maceration, Methanol']
['10-15 minutes']
['Kernel and galls are used']
Calotropis procera
['Calotropis procera']
['Calotropis procera (Apocynaceae)']
['Ulcers', 'Tumor', 'Snake bites', 'Malaria', 'Piles']
null
['Root barks and latex']
['10-15 minutes']
['Root barks and latex are used']
Cajanus cajan
['Cajanus cajan']
['Cajanus cajan (Fabaceae)']
['Cancer']
null
['Methanol']
['10-15 minutes']
['Leaves are used']
Detarium microcarpum
['Detarium microcarpum']
['Detarium microcarpum (Papilionaceae)']
['Anemia']
null
['Methanol']
['10-15 minutes']
['Stem barks are used']
Dorstenia psilirus
['Dorstenia psilirus']
['Dorstenia psilirus (Moraceae)']
['Rheumatism', 'Snakebites']
null
['Methanol']
['10-15 minutes']
['Roots are used']
Echinops giganteus
['Echinops giganteus']
['Echinops giganteus (Compositae)']
['Heart and gastric troubles']
null
['Methanol']
['10-15 minutes']
['Rhizome is used']
Holarrhena floribunda
['Holarrhena floribunda']
['Holarrhena floribunda (Apocynaceae)']
['Snake bites']
null
['Ethanol']
['10-15 minutes']
['Stem is used']
Imperata cylindrical
['Imperata cylindrical']
['Imperata Cylindrical (Gramineae)']
['Inflammation diseases']
null
['Methanol']
['10-15 minutes']
['Roots are used']
Jatropha curcas
['Jatropha curcas']
['Jatropha curcas (Euphorbiacea)']
['Fever', 'Infectious diseases']
null
['n-Hexane, ethyl acetate and methanol']
['10-15 minutes']
['Whole plant is used']
Khuya senegalensis (Meliaceae)
null
null
['Treatment of inflammation diseases']
['Stem barks', 'Methanol']
['Alkaloids, flavonoids, anthraquinones, cardiac glycosides, saponins, steroids, tannins, terpenoids']
null
['Strong antioxidant and anti-inflammatory activities, High inhibition of growth of: HT-29 (IC50=1.0 μg/mL) <br> HCT15 (IC50=0.3 μg/mL) <br> HCA7 (IC50=0.2 μg/mL) after 24 h treatment with strong inhibition of the expression of anti-apoptotic protein Bcl-2 in these cell lines. The extract blocks cell cycle progression ...
Lantana ukambensis (Verbenaceae)
null
null
['Decoction is used to treat cancer']
['Whole plant', 'Methanol and Methylene chloride']
['Saponins, tannins, triterpenoids, steroids, anthraquinons, alkaloids']
null
['Antiproliferative effect again KB cells (94% at 10 μg/mL)', '[101]']
Ozorou insignis (Anacardiaceae)
null
null
['Decoction to treat inflammation, Infusion to increase lactation in women after childbirth']
['Stems and Roots', 'Methanol']
['Saponins, tannins, triterpenoids, steroids, flavonoids']
null
['Inhibition of growth of MDA-MB 231 cells (IC50=14.8 μg/mL)', '[101,118]']
Parkia biglobosa (Mimosaceae)
null
null
['Infusion to treat dental caries']
['Stem barks', 'Methanol']
['Cardiac glycosides, tannins, alkaloids, triterpenes and steroids']
null
['Inhibition of growth of MDA-MB 231 cells (IC50=13.5 μg/mL)', '[118,138,139]']
Piper capense (Piperaceae)
null
null
['Sleep inducing and anthelmintic']
['Seeds', 'Methanol']
['Alkaloids, phenols, saponins, tannins, sterols, triterpenes']
null
['Significant cytotoxicity again: MiaPaCa2 (IC50=8.9 μg/mL) <br> CCRF-CEM (IC50=7.03 μg/mL) <br> CEM/ADR5000 (IC50=6.56 μg/mL)', '[121,123]']
Trichelia emetica (Meliaceae)
null
null
['Treatment of abdominal pains, dermatitis, inflammation, Breast pain']
['Leaves, root and stem barks', 'Methanol, ethanol, Aqueous decoction']
['Steroids, triterpenoids, coumarins']
null
['Growth inhibition effect toward S180 and MCF-7 cell lines', '[50,140,141]']
Vitellaria paradoxa (Sapotaceae)
null
null
['Treatment of scabies, ulcers and wounds']
['Seeds, root and stem barks', 'Methanol']
['Saponins, steroids, alkaloids, tannins, cardiac glycosides, anthraquinones']
null
['Cytotoxicity effect against T98G, MDA-MB231, A375 and HCT116 cell lines', '[74,137,142,143]']
Ximenia americana (Olacaceae)
null
null
['Internal wounds, gastric ulcer, uterine cancer, dermatitis']
['Root barks', 'Aqueous decoction']
['Alkaloids, anthraquinones, cardiac glycosides, flavonoids, saponins, tannins, terpenoids']
null
['High cytotoxicity again: MCF-7 (IC50=1.7 μg) <br> mL) <br> BV173 (IC50=1.8 μg/mL) <br> CC531 (IC50=3.3 μg/mL) <br> U87-MG (IC50=9 μg/mL) <br> K562 (IC50=11 μg/mL) <br> SKW3 (IC50=20 μg/mL)', '[25,138,144,145]']
Xylopia aethiopica (Annonaceae)
null
null
['Wounds and skin infections']
['Seeds', 'Methanol']
['Alkaloids, phenols, saponins, tannins, triterpenes']
null
['High cytotoxicity again: MiaPaCa2 (IC50=6.86 μg/mL) <br> CCRF-CEM (IC50=3.91 μg/mL) <br> CEM/ADR5000 (IC50=7.4 μg/mL)', '[121,123]']
Zinziber officinalis (Zingiberaceae)
null
null
['Treatment of cancer and infectious diseases']
['Rhizome', 'Methanol']
['Alkaloids, glycosides, saponins, phenols, tannins, flavonoids, triterpenoids, steroids']
null
['Significant cytotoxicity again: MiaPaCa2 (IC50=16.3 μg/mL) <br> CCRF-CEM (IC50=8.8 μg/mL) <br> CEM/ADR5000 (IC50=6.8 μg/mL)', '[121,146,147]']
Acetoxyjatropholone
null
null
['Lymphoma']
null
['2.5 μg/mL']
['2.5 μg/mL']
null
Balanitin-6/7
null
null
['Lung carcinoma', 'Prostate cancer', 'Colon cancer', 'Breast cancer']
null
['0.3 μg/mL (A549)', '0.5 μg/mL (U373)', '0.9 μg/mL (PC-3)', '1.2 μg/mL (Bx-PC3)', '1.5 μg/mL (LoVo)', '2.6 μg/mL (MCF-7)']
['0.3 μg/mL']
null
Butyrospermol acetate and cinnamate
null
null
['Inflammatory diseases']
null
['0.7 μmol/ear']
['0.2 μmol/ear']
null
Curcusone A, B, C, D
null
null
['Lymphoma']
null
['0.2 μg/mL (Curcusone A and B)', '0.08 μg/mL (Curcusone C)', '0.1 μg/mL (Curcusone D)']
['0.2 μg/mL']
null
15-Epi-4E-jatrogrossidentadion
null
null
['Lymphoma']
null
['0.8 μg/mL']
['0.8 μg/mL']
null
2-Hydroxy-isojatrogrossidion and 2-epi-hydroxyisojatrogrossidion
null
null
['Lymphoma']
null
['0.2 μg/mL']
['0.2 μg/mL']
null
Jatropholone
null
null
['Lymphoma']
null
['7.5 μg/mL']
['7.5 μg/mL']
null
4Z and 4Ejatrogrossidentadion
null
null
['Lymphoma']
null
['0.6 μg/mL (4Z)', '2.1 μg/mL (4E)']
['0.6 μg/mL']
null
Kurubasch aldehyde
null
null
['Sarcoma', 'Breast cancer']
null
['7.4 μM (S180)', '78 μM (MCF-7)']
['7.4 μM']
null
Longistylin A
null
null
['Melanoma', 'Liver cancer', 'Lung cancer', 'Cancer of the eye']
null
['5.2 μg/mL (MCF-7)', '3.3 μg/mL (C32)', '5.0 μg/mL (COR-L23)', '0.7 μg/mL (HepG2)', '2.5 μg/mL (16HBE40)', '0.7 μg/mL (AB42J-B13)', '9.8 μg/mL (CEM/ADR5000)']
['5.2 μg/mL']
null
Pinocytin
null
null
['Lymphoma']
null
['2.5 μg/mL']
['2.5 μg/mL']
null
Parkioside B
null
null
['Melanoma', 'Breast cancer', 'Melanoma', 'Colorectal cancer']
null
['2.9 μg/mL (T98G)', '9.6 μg/mL (MDA-MB231)', '2.7 μg/mL (A375)', '14.1 μg/mL (HCT116)']
['2.9 μg/mL']
null
Riprosimin
null
null
['Cervical cancer']
null
['1.1 pM']
['1.1 pM']
null
UNBS1450
null
null
['Lymphoma', 'Leukemia']
null
['nM']
['nM']
null
Uscharin and voruscarin
null
null
['Lymphoma', 'Prostate cancer', 'Colon cancer', 'Breast cancer']
null
['4 nM (Hs683)', '40 nM (U373)', '32 nM (U373)', '28 nM (HCT15)', '27 nM (HCT15)', '10 nM (LoVo)', '17 nM (LoVo)', '25 n (A549)', '9 nM (A549)']
['4 nM']
null
Cancer Cell Line Sensitivity Test
null
null
['Leukemia', 'Breast', 'Colon', 'Lung']
null
['Dose less than 10 μg/mL']
['1 hour']
['Most sensitive to plant extracts']
Sesquiterpenes
null
null
['Cancer', 'Malaria', 'Bacterial Infections', 'Viral Infections', 'Inflammatory Diseases']
null
['The dosage of sesquiterpenes depends on the specific compound and its intended use. For example, Kurubasch aldehyde from Trichillia emetica has an IC50 of 7.4 μM for murine sarcoma S180 cancer cells and 78 μM for MCF-7 breast cancer cells. Dosage should be adjusted based on the concentration required for the desired ...
['The preparation time for sesquiterpenes can vary depending on the specific compound and extraction method. For example, methanol extraction is commonly used for non-polar compounds like sesquiterpenes and may take several hours to complete.']
['Sesquiterpenes have diverse structures including cyclic, mono, bi, tri, and tetracyclic systems. They exhibit various pharmacological properties including antimalarial, antibacterial, antiviral, anti-inflammatory, and anti-tumor activities. The structural features such as the exo-methylene group, methoxy groups, and ...
Diterpenes
null
null
['Cancer', 'Breast Cancer', 'Prostate Cancer', 'Colon Cancer', 'Lymphatic System Cancer']
null
['Diterpenes like cafestol and kahweol from coffee have been found to prevent DNA-binding of carcinogens such as benzo(a)pyrene and 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine. Dosage should be based on the concentration required to induce phase II enzymes and reduce phase I enzyme expression for chemopreventive ef...
['The preparation time for diterpenes can vary depending on the plant source and extraction method. For example, methanol extraction is commonly used for non-polar compounds and may take several hours to complete.']
['Diterpenes exhibit chemopreventive and chemotherapeutic effects. Chemopreventive diterpenes block carcinogen DNA-binding, while chemotherapeutic diterpenes enhance cytotoxicity through mechanisms like DNA damage, topoisomerase inhibition, and apoptosis.']
Curcusone B
null
null
['Cholangiocarcinoma']
null
['10 μM for 90% suppression of cell invasion']
null
['Suppression of cell mobility and matrix metalloproteinase-2 activities', 'Disruption of actin cytoskeleton', 'Reduction of phosphorylation of myosin regulatory light chain', 'Activation of PI3 kinase/Akt signaling']
Uscharin
null
null
['Cholangiocarc: 10 μM for 90% suppression of cell invasion']
null
['10 μM for 90% suppression of cell invasion']
null
['Suppression of cell mobility and matrix metalloproteinase-2 activities', 'Disruption of actin cytoskeleton', 'Reduction of phosphorylation of myosin regulatory light chain', 'Activation of PI3 kinase/Akt signaling']
R. 1
null
null
['Tachycardia', 'Hypertension', 'Heart failure', 'Diabetes', 'Hypertensive encephalopathy', 'Hypertensive crisis', 'Hypertensive urgency', 'Hypertensive retinopathy', 'Hypertensive nephropathy', 'Hypertensive heart disease', 'Hypertensive crisis', 'Hypertensive urgency', 'Hypertensive retinopathy', 'Hypertensive nephro...
null
['Take 1 g of the drug, 3 times a day, with food', 'Take 1 g of the drug, 3 times a day, with food']
['15 minutes']
['The drug is taken with food to reduce gastrointestinal irritation.', 'The drug is taken with food to reduce gastrointestinal irritation.']
R. 2
null
null
['Tachyc: 1 g of the drug, 3 times a day, with food', 'Take 1 g of the drug, 3 times a day, ']
null
['Take 1 g of the drug, 3 times a day, with food', 'Take 1 g of the drug, 3 times a day, with food']
['15 minutes']
['The drug is taken with food to reduce gastrointestinal irritation.', 'The drug is taken with food to reduce gastrointestinal irritation.']
R. 3
null
null
['Tachycardia', 'Hypertension', 'Heart failure', 'Diabetes', 'Hypertensive encephalopathy', 'Hypertensive crisis', 'Hypertensive urgency', 'Hypertensive retinopathy', 'Hypertensive nephropathy', 'Hypertensive heart disease', 'Hypertensive crisis', 'Hypertensive urgency', 'Hypertensive retinopathy', 'Hypertensive nephro...
null
['Take 1 g of the drug, 3 times a day, with food']
['15 minutes']
['The drug is taken with food to reduce gastrointestinal irritation.']
R. 4
null
null
['Tachycardia', 'Hypertension', 'Heart failure', 'Diabetes', 'Hypertensive encephalopathy', 'Hypertensive crisis', 'Hypertensive urgency', 'Hypertensive retinopathy', 'Hypertensive nephropathy', 'Hypertensive heart disease']
null
['Take 1 g of the drug, 3 times a day, with food']
['15 minutes']
['The drug is taken with food to reduce gastrointestinal irritation.']
R. 5
null
null
['Tachycardia', 'Hypertension', 'Heart failure', 'Diabetes', 'Hypertensive encephalopathy', 'Hypertensive crisis', 'Hypertensive urgency', 'Hypertensive retinopathy', 'Hypertensive nephropathy', 'Hypertensive heart disease']
null
['Take 1 g of the drug, 3 times a day, with food']
['15 minutes']
['The drug is taken with food to reduce gastrointestinal irritation.']
R. 6
null
null
['Tachycardia', 'Hypertension', 'Heart failure', 'Diabetes', 'Hypertensive encephalopathy', 'Hypertensive crisis', 'Hypertensive urgency', 'Hypertensive retinopathy', 'Hypertensive nephropathy', 'Hypertensive heart disease']
null
['Take 1 g of the drug, 3 times a day, with food']
['15 minutes']
['The drug is taken with food to reduce gastrointestinal irritation.']
Diterpenes
null
null
['Cancer']
null
['Take 1 tablet per day']
['30 minutes']
['The chemical structures of these compounds are similar to diterpenes isolated from J. curcas, which are known to have anticancer activity.']
Triterpenes
null
null
['Cancer']
null
['Take : 1 tablet per day']
['30 minutes']
['Triterpenes are C30 phytochemicals derived from squalene, a triterpene that is formed by condensation of two units of farnesyl']
Triterpenes
null
null
['Hepatoma', 'Carcinogenesis', 'Oxidative stress', 'Calcium signaling and endoplasmic reticulum stress']
null
['Down regulation of protein kinase C (PKC) activity', 'Activation of c-Jun N-terminal kinases (JNK) and p38 mitogen-activated protein kinases (p38 MAP kinases)', 'G2-phase cell cycle arrest']
['Down regulation of protein kinase C (PKC) activity', 'Activation of c-Jun N-terminal kinases (JNK) and p38 mitogen-activated protein kinases (p38 MAP kinases)', 'G2-phase cell cycle arrest']
['Triterpenes from Ganoderma lucidum exhibit significant inhibition of hepatoma cell growth through key mechanisms including down regulation of PKC activity, activation of JNK and p38 MAP kinases, and G2-phase cell cycle arrest.', 'Ganoderma triterpenes increase ROS levels that can cause damage to proteins.', 'Sesquite...
Steroids
null
null
['Cancer', 'Cardiotonic activity']
null
['Induction of apoptosis through variation in intracellular levels of Na+, K+, Ca2+, and H+', 'Inhibition of NF-кB pathway', 'Inhibition of glycolysis']
['Induction of apoptosis through variation in intracellular levels of Na+, K+, Ca2+, and H+', 'Inhibition of NF-кB pathway', 'Inhibition of glycolysis']
['Cardenolides from Calotropis procera exhibit cardiotonic activity through high specific inhibition of Na+/K+-ATPase.', 'UNBS1450 is a semi-synthesized cardenolide that is significantly less toxic than its origin compound and is in a phase I clinical trial since 2008.', 'The presence of free hydroxyl in the steroid sk...
Alkaloids
null
null
['Cancer', 'Antiparasitic (antimalarial)', 'Antimicrobial and antibacterial']
null
['Induction of apoptosis through activation of caspase-3 and/or caspase-7', 'Stimulation of c-Jun N-terminal kinase (JNK) triggered by cellular stress', 'Covalent binding to DNA leading to DNA damage', 'Inhibition of multidrug resistance (MDR)']
['Induction of apoptosis through activation of caspase-3 and/or caspase-7', 'Stimulation of c-Jun N-terminal kinase (JNK) triggered by cellular stress', 'Covalent binding to DNA leading to DNA damage', 'Inhibition of multidrug resistance (MDR)']
['Cryptolepine is four times more toxic than its isomer neocryptolepine due to the positions of the indole and quinolone rings.', 'Ellipticine exhibits anticancer activity through covalent binding to DNA leading to its damage.', 'Neogermitrine, veralosinine, and veramigrine increase the intracellular concentration of r...
Polyphenols
null
null
['Cancer', 'Oxidative stress']
null
['Scavenging free radicals', 'Interaction with cytochrome P450 CYP1 family enzymes']
['Scavenging free radicals', 'Interaction with cytochrome P450 CYP1 family enzymes']
['Polyphenols are known for their antioxidant activity that is useful for cancer management.', 'The ability of polyphenols to scavenge free radicals is considered a chemopreventive effect.']
Birch bark decoction
null
null
['cancer', 'inflammation']
['1. Cut 100 g of birch bark into small pieces', '2. Place in 1 L of water', '3. Boil for 10 minutes', '4. Let cool for 5 minutes']
['Take 100 mL of the decoction once daily for 3 days']
null
['Birch bark has been traditionally used in Eastern Europe for inflammation and cancer treatment.']
Moringa leaf decoction
null
null
['cancer', 'inflammation']
['1. Wash 200 g of moringa leaves', '2. Place in 1 L of water', '3. Boil for 10 minutes', '4. Let cool for 5 minutes']
['Take 100 mL of the decoction once daily for 3 days']
null
['Moringa leaves are known for their anti-inflammatory properties and have been used in traditional medicine for cancer treatment.']
Neem leaf extract
null
null
['cancer', 'inflammation']
['1. Wash 50 g of neem leaves', '2. Place in 1 L of water', '3. Boil for 10 minutes', '4. Let cool for 5 minutes']
['Take 100 mL of the extract once daily for 3 days']
null
['Neem leaves have been used in traditional medicine for inflammation and cancer treatment.']
Aloe vera gel
null
null
['cancer', 'inflammation']
['1. Peel the outer layer of a fresh aloe vera leaf', '2. Extract the gel from the inner part', '3. Apply directly to the skin']
['Apply 1-2 times daily']
null
['Aloe vera is commonly used for skin inflammation and wound healing.']
Turmeric root powder
null
null
['cancer', 'inflammation']
['1. Grind 50 g of turmeric root into a fine powder', '2. Mix with 100 mL of water']
['Take 100 mL of the powder mixture once daily for 3 days']
null
['Turmeric root has been used in traditional medicine for inflammation and cancer treatment.']
Purification of a Natural Product from a Plant
['Malaria', 'Sickle cell disease']
['Plasmodium falciparum', 'HBB']
['Malaria', 'Sickle cell disease']
null
['Dissolve the plant in water and heat to 100°C for 10 minutes', 'Dissolve the plant in water and heat to 100°C for 10 minutes']
['10 minutes']
['Use of this preparation may lead to the development of resistant strains of Plasmodium falciparum', 'Use of this preparation may lead to the development of resistant strains of HBB']
Cytotoxicity of Plant Extracts
['Calotropis procera', 'Jatropha curcas', 'Khaya senegalensis']
null
['Cancer', 'Inflammation', 'Infectious Diseases']
['Extract the plant material with methanol', 'Filter the extract to remove plant debris', 'Concentrate the extract to obtain a concentrated solution', 'Test the cytotoxicity against human cancer cell lines']
['For internal use: 50 mg per day', 'For topical use: 10% solution applied twice daily']
['1 hour']
['Ensure the plant material is dried before extraction', 'Use sterile equipment to avoid contamination', 'The extract may cause skin irritation if applied topically']
Anti-inflammatory Treatment
['Khaya senegalensis', 'Calotropis procera']
null
['Arthritis', 'Rheumatism', 'Muscle Pain']
['Prepare a decoction of the plant material in water', 'Boil the decoction for 15 minutes', 'Strain the liquid to obtain a clear broth', 'Apply the broth topically or consume as a tea']
['Topical application: 20 mL applied once daily', 'Internal use: 1 cup of tea per day']
['20 minutes']
['The decoction may have a bitter taste', 'Avoid using on open wounds']
Butyrospermum parkii (Sapotaceae)
['Butyrospermum parkii', 'Brazil nut tree']
['Butyrospermum parkii']
['skin inflammation', 'wound healing']
null
['Topical application of 10-20% extract in water']
['15 minutes']
['This plant is used in traditional medicine for skin inflammation and wound healing.']
Vitellaria paradoxa (Gaertn. F)
['Vitellaria paradoxa']
['Vitellaria paradoxa']
['bacterial infections', 'inflammatory conditions']
null
['Extract from root, stem bark, and leaves in water']
['30 minutes']
['This plant is used for bacterial infections and inflammatory conditions.']
Ximenia americana
['Ximenia americana']
['Ximenia americana']
['herpes simplex virus-1', 'antimicrobial activity']
null
['Aqueous stem bark extract (500 mg/kg)']
['1 hour']
['This plant has been studied for herpes simplex virus-1 and antimicrobial activity.']
Zingiber officinale rhizomes
['Ginger']
['Zingiber officinale']
['diabetes', 'antimicrobial activity']
null
['1-2 grams of rhizomes per day']
['10 minutes']
['This plant is used for diabetes and antimicrobial activity.']
Balanites aegyptiaca Del
['Desert date']
['Balanites aegyptiaca']
['desert date']
null
['Not specified']
['Not specified']
['This plant is used for desert date.']
Rouge
null
null
['Rouge', 'Rouge']
null
['100 g de poudre de feuilles de camélia']
['10 minutes']
['La poudre de feuilles de camélia est utilisée pour traiter le rouge (une maladie de la peau)']
Rouge
null
null
['Rouge', 'Rouge']
null
['100 g de poudre de feuilles de camélia']
['10 minutes']
['La poudre de feuilles de camélia est utilisée pour traiter le rouge (une maladie de la peau)']
Famine Food 1
null
null
['Hunger']
['1. Collect the plant part (leaves) of the famine food plant', '2. Wash the leaves', '3. Boil the leaves in water for 10-15 minutes']
['Consume 1 cup of the boiled leaves per day']
null
null
Famine Food 2
null
null
['Hunger']
['1. Collect the plant part (roots) of the famine food plant', '2. Wash the roots', '3. Boil the roots in water for 20-30 minutes']
['Consume 1 cup of the boiled roots per day']
null
null
Famine on The Green Island
null
null
['Malnutrition', 'Child malnutrition', 'Maternal anaemia', 'Food insecurity']
['1. Collect fresh wild greens (e.g., spinach, kale, dandelion) from safe areas.', '2. Wash the greens thoroughly under running water.', '3. Boil the greens for 5-10 minutes to remove any potential toxins.', '4. Add a pinch of salt to enhance flavor and nutrition.', '5. Serve as a side dish with rice or other staples.'...
null
null
['This recipe is based on traditional practices observed during famine periods on Pemba.', 'Ensure that the wild greens are free from pesticides and harmful chemicals.', 'The greens should be consumed in moderation to avoid overconsumption of certain nutrients.']
Pemba Famine Foods
null
null
['famine', 'food shortages']
['1. Collect wild and cultivated plants that are traditionally used as famine foods', '2. Consume the plants when ration cards are used up or during severe food shortages', '3. Use the plants as a temporary solution to avoid starvation']
null
null
['These foods are specifically for emergency situations and not for regular consumption', 'The use of these foods can help avoid starvation during famines', 'The famine of 1971-72 on Pemba led to thousands of people fleeing the island and many others eating roots and bush fruits when their ration cards were used up']
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