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|---|---|---|---|---|---|---|---|---|---|---|---|---|
factoid | What disease can be treated with Glofitamab? | ['DLBCL'] | [
"DLBCL",
"Diffuse Large B-cell Lymphoma",
"Diffuse Large B Cell Lymphoma",
"DLBCL lymphoma",
"Large B-cell lymphoma"
] | ['Glofitamab is being tested for treatment of DLBCL after CAR T-Cell Therapy'] | [
"http://www.ncbi.nlm.nih.gov/pubmed/35626120",
"http://www.ncbi.nlm.nih.gov/pubmed/34941996",
"http://www.ncbi.nlm.nih.gov/pubmed/36198538"
] | [
{
"beginSection": "title",
"document": "http://www.ncbi.nlm.nih.gov/pubmed/35626120",
"endSection": "title",
"offsetInBeginSection": 0,
"offsetInEndSection": 78,
"text": "Glofitamab Treatment in Relapsed or Refractory DLBCL after CAR T-Cell Therapy."
},
{
"beginSection": "abstract",
... | 12 | BioASQ-training12b | null | null | 63eeeb70f36125a426000005 | bioasq_factoid |
yesno | Does metformin interfere thyroxine absorption? | ['No'] | [
"No"
] | ['There are not reported data indicating that metformin interferes with thyroxine absorption'] | [
"http://www.ncbi.nlm.nih.gov/pubmed/23554450",
"http://www.ncbi.nlm.nih.gov/pubmed/23264396",
"http://www.ncbi.nlm.nih.gov/pubmed/23244059",
"http://www.ncbi.nlm.nih.gov/pubmed/23154888",
"http://www.ncbi.nlm.nih.gov/pubmed/23072197",
"http://www.ncbi.nlm.nih.gov/pubmed/21748540",
"http://www.ncbi.nlm.n... | [] | 5 | BioASQ-training5b | [
"http://www.nlm.nih.gov/cgi/mesh/2012/MB_cgi?field=uid&exact=Find+Exact+Term&term=D008687",
"http://www.nlm.nih.gov/cgi/mesh/2012/MB_cgi?field=uid&exact=Find+Exact+Term&term=D013974",
"http://www.nlm.nih.gov/cgi/mesh/2012/MB_cgi?field=uid&exact=Find+Exact+Term&term=D000042"
] | null | 51406e6223fec90375000009 | bioasq_yesno |
yesno | Is there a relation between ANP and transcapillary albumin escape? | ['yes'] | [
"yes"
] | A possible role of ANP gene in conferring protection from nephropathy and microvascular damage in type 1 diabetes is present.
ANP infusion in healthy subjects caused a shift of plasma water and electrolytes from the circulation, with albumin escape as a secondary phenomenon | [
"http://www.ncbi.nlm.nih.gov/pubmed/10405209",
"http://www.ncbi.nlm.nih.gov/pubmed/7579054",
"http://www.ncbi.nlm.nih.gov/pubmed/8432776",
"http://www.ncbi.nlm.nih.gov/pubmed/9815090",
"http://www.ncbi.nlm.nih.gov/pubmed/9338510",
"http://www.ncbi.nlm.nih.gov/pubmed/8065837",
"http://www.ncbi.nlm.nih.go... | [
{
"beginSection": "abstract",
"document": "http://www.ncbi.nlm.nih.gov/pubmed/10405209",
"endSection": "abstract",
"offsetInBeginSection": 2008,
"offsetInEndSection": 2257,
"text": "Thus, in a large ethnically homogeneous cohort of diabetic subjects, our data show: (1) a significant associat... | 5 | BioASQ-training5b | [
"http://www.nlm.nih.gov/cgi/mesh/2014/MB_cgi?field=uid&exact=Find+Exact+Term&term=D009320",
"http://www.nlm.nih.gov/cgi/mesh/2014/MB_cgi?field=uid&exact=Find+Exact+Term&term=D000418",
"http://www.nlm.nih.gov/cgi/mesh/2014/MB_cgi?field=uid&exact=Find+Exact+Term&term=D017461",
"http://www.nlm.nih.gov/cgi/mesh/2... | [] | 5321b8a39b2d7acc7e000009 | bioasq_yesno |
yesno | Has dupilumab been FDA approved for atopic dermatitis? | ['yes'] | [
"yes"
] | ['Yes, dupilumab has been approved by FDA for atopic dermatitis.'] | [
"http://www.ncbi.nlm.nih.gov/pubmed/31603635",
"http://www.ncbi.nlm.nih.gov/pubmed/32344789",
"http://www.ncbi.nlm.nih.gov/pubmed/32439390",
"http://www.ncbi.nlm.nih.gov/pubmed/31364023",
"http://www.ncbi.nlm.nih.gov/pubmed/30785362"
] | [
{
"beginSection": "abstract",
"document": "http://www.ncbi.nlm.nih.gov/pubmed/31364023",
"endSection": "abstract",
"offsetInBeginSection": 315,
"offsetInEndSection": 575,
"text": "Recent advances and understanding of the pathogenesis of AD have resulted in new therapies that target specific ... | 11 | BioASQ-training11b | null | null | 606b718994d57fd87900006b | bioasq_yesno |
yesno | Does Rad9 interact with Aft1 in S.cerevisiae? | ['yes'] | [
"yes"
] | ['Yes. Rad9 functions together with Aft1 on DNA damage-prone chromatin to facilitate genome surveillance, thereby ensuring rapid and effective response to possible DNA damage events.'] | [
"http://www.ncbi.nlm.nih.gov/pubmed/25300486"
] | [
{
"beginSection": "title",
"document": "http://www.ncbi.nlm.nih.gov/pubmed/25300486",
"endSection": "title",
"offsetInBeginSection": 0,
"offsetInEndSection": 142,
"text": "Rad9 interacts with Aft1 to facilitate genome surveillance in fragile genomic sites under non-DNA damage-inducing condit... | 5 | BioASQ-training5b | [
"http://www.uniprot.org/uniprot/RAD9_SCHPO",
"http://www.uniprot.org/uniprot/RAD9B_BOVIN",
"http://www.uniprot.org/uniprot/RAD9B_RAT",
"http://www.uniprot.org/uniprot/RAD9B_MOUSE",
"http://www.uniprot.org/uniprot/RAD9A_HUMAN",
"http://www.uniprot.org/uniprot/RAD9A_MOUSE",
"http://www.uniprot.org/uniprot... | [] | 56b9c937ac7ad10019000001 | bioasq_yesno |
factoid | What is the effect of carbamazepine on CYP3A4? | ['Induces', 'inducer', 'induction'] | [
"Induces",
"inducer",
"induction"
] | ['Carbamazepine is an inducer of CYP3A4.'] | [
"http://www.ncbi.nlm.nih.gov/pubmed/31650711"
] | [
{
"beginSection": "abstract",
"document": "http://www.ncbi.nlm.nih.gov/pubmed/31650711",
"endSection": "abstract",
"offsetInBeginSection": 274,
"offsetInEndSection": 379,
"text": "Carbamazepine, a UGT and cytochrome P450 3A4 inducer, is a first-line treatment for trigeminal neuralgia."
}
] | 11 | BioASQ-training11b | null | null | 606ab57394d57fd87900004f | bioasq_factoid |
factoid | Do archaeal genomes contain one or multiple origins of replication? | ['mostly multiple'] | [
"mostly multiple",
"multiple",
"mostly",
"primarily multiple",
"largely multiple"
] | Some archaea replicate from single origins but most archaea and all eukaryotes replicate using multiple origins. | [
"http://www.ncbi.nlm.nih.gov/pubmed/15197606",
"http://www.ncbi.nlm.nih.gov/pubmed/12646230",
"http://www.ncbi.nlm.nih.gov/pubmed/12237132",
"http://www.ncbi.nlm.nih.gov/pubmed/24185008",
"http://www.ncbi.nlm.nih.gov/pubmed/23375370",
"http://www.ncbi.nlm.nih.gov/pubmed/22978470",
"http://www.ncbi.nlm.n... | [
{
"beginSection": "abstract",
"document": "http://www.ncbi.nlm.nih.gov/pubmed/15197606",
"endSection": "abstract",
"offsetInBeginSection": 1056,
"offsetInEndSection": 1407,
"text": "Therefore, these lines of evidence strongly suggest that the identified region is a replication origin, which ... | 5 | BioASQ-training5b | [
"http://www.nlm.nih.gov/cgi/mesh/2014/MB_cgi?field=uid&exact=Find+Exact+Term&term=D018741",
"http://www.nlm.nih.gov/cgi/mesh/2014/MB_cgi?field=uid&exact=Find+Exact+Term&term=D020745"
] | [] | 52fe58f82059c6d71c00007a | bioasq_factoid |
factoid | What disease can be treated with Trofinetide? | ['Rett syndrome'] | [
"Rett syndrome",
"Rett's syndrome",
"Rett disorder",
"Rett's disorder",
"MECP2-related disorder",
"MECP2 syndrome"
] | ['Trofinetide is approved for Rett syndrome.'] | [
"http://www.ncbi.nlm.nih.gov/pubmed/28964591",
"http://www.ncbi.nlm.nih.gov/pubmed/37714122",
"http://www.ncbi.nlm.nih.gov/pubmed/38017349",
"http://www.ncbi.nlm.nih.gov/pubmed/37568516",
"http://www.ncbi.nlm.nih.gov/pubmed/37291210",
"http://www.ncbi.nlm.nih.gov/pubmed/35622206",
"http://www.ncbi.nlm.n... | [
{
"beginSection": "title",
"document": "http://www.ncbi.nlm.nih.gov/pubmed/37291210",
"endSection": "title",
"offsetInBeginSection": 0,
"offsetInEndSection": 75,
"text": "Trofinetide for the treatment of Rett syndrome: a randomized phase 3 study."
},
{
"beginSection": "abstract",
... | 13 | BioASQ-training13b | null | null | 65d134bd1930410b13000037 | bioasq_factoid |
factoid | Which species of bacteria did the mitochondria originate from? | [['Biologists agree that the ancestor of mitochondria was an alpha-proteobacterium.']] | [
"alpha-proteobacterium",
"α-proteobacterium",
"alpha proteobacteria",
"alpha proteobacterium",
"alphaproteobacteria",
"alphaproteobacterium",
"alpha proteobacterium ancestor",
"ancestor of mitochondria"
] | ['Biologists agree that the ancestor of mitochondria was an alpha-proteobacterium. Although the Alphaproteobacteria are thought to be the closest relatives of the mitochondrial progenitor, there is dispute as to what its particular sister group is. Accumulating evolutionary data point to a monophyletic origin of mitoch... | [
"http://www.ncbi.nlm.nih.gov/pubmed/21300273",
"http://www.ncbi.nlm.nih.gov/pubmed/21217797",
"http://www.ncbi.nlm.nih.gov/pubmed/17251118",
"http://www.ncbi.nlm.nih.gov/pubmed/16822756",
"http://www.ncbi.nlm.nih.gov/pubmed/12594925",
"http://www.ncbi.nlm.nih.gov/pubmed/11508688",
"http://www.ncbi.nlm.n... | [
{
"beginSection": "abstract",
"document": "http://www.ncbi.nlm.nih.gov/pubmed/21300273",
"endSection": "abstract",
"offsetInBeginSection": 0,
"offsetInEndSection": 412,
"text": "Recently, α-proteobacteria have been shown to possess virus-like gene transfer agents that facilitate high frequen... | 5 | BioASQ-training5b | [
"http://www.nlm.nih.gov/cgi/mesh/2016/MB_cgi?field=uid&exact=Find+Exact+Term&term=D001419",
"http://amigo.geneontology.org/amigo/term/GO:0005739",
"http://www.nlm.nih.gov/cgi/mesh/2016/MB_cgi?field=uid&exact=Find+Exact+Term&term=D008928"
] | [] | 56c58f1b5795f9a73e000001 | bioasq_factoid |
factoid | What is the enzymatic activity of PARL? | ['PARL are serine proteases'] | [
"PARL",
"Presenilin-associated rhomboid-like protein",
"Presenilin-associated rhomboid-like",
"PARL serine protease"
] | ['the mitochondrial protease presenilin-associated rhomboid-like (PARL). Rhomboids are a recently discovered family of widely distributed intramembrane serine proteases.'] | [
"http://www.ncbi.nlm.nih.gov/pubmed/17938163",
"http://www.ncbi.nlm.nih.gov/pubmed/21415861",
"http://www.ncbi.nlm.nih.gov/pubmed/21355049",
"http://www.ncbi.nlm.nih.gov/pubmed/19859837"
] | [
{
"beginSection": "abstract",
"document": "http://www.ncbi.nlm.nih.gov/pubmed/21355049",
"endSection": "abstract",
"offsetInBeginSection": 743,
"offsetInEndSection": 970,
"text": "Here we demonstrate that the mitochondrial protease presenilin-associated rhomboid-like (PARL) can affect the pr... | 6 | BioASQ-training6b | null | null | 58dfe6b56fddd3e83e000004 | bioasq_factoid |
factoid | ZF2001 is used for which disease? | ['COVID-19'] | [
"COVID-19",
"Coronavirus Disease 2019",
"SARS-CoV-2 infection",
"2019-nCoV",
"Novel Coronavirus",
"Wuhan Coronavirus",
"COVID",
"Coronavirus"
] | ['ZF2001 is used for COVID-19.'] | [
"http://www.ncbi.nlm.nih.gov/pubmed/35617368",
"http://www.ncbi.nlm.nih.gov/pubmed/35568034",
"http://www.ncbi.nlm.nih.gov/pubmed/35634276",
"http://www.ncbi.nlm.nih.gov/pubmed/35596222"
] | [
{
"beginSection": "title",
"document": "http://www.ncbi.nlm.nih.gov/pubmed/35617368",
"endSection": "title",
"offsetInBeginSection": 0,
"offsetInEndSection": 217,
"text": "Safety and immunogenicity of heterologous boost immunization with an adenovirus type-5-vectored and protein-subunit-base... | 12 | BioASQ-training12b | null | null | 63f03c47f36125a42600001e | bioasq_factoid |
factoid | Which plant does oleuropein originate from? | ['Olive tree'] | [
"Olive tree",
"Olea europaea",
"European olive",
"Olive",
"Olive plant"
] | ['Oleuropein originates from olive trees, and is specifically found in olive leaf extracts.'] | [
"http://www.ncbi.nlm.nih.gov/pubmed/29099642"
] | [
{
"beginSection": "title",
"document": "http://www.ncbi.nlm.nih.gov/pubmed/29099642",
"endSection": "title",
"offsetInBeginSection": 0,
"offsetInEndSection": 88,
"text": "Oleuropein Is Responsible for the Major Anti-Inflammatory Effects of Olive Leaf Extract."
},
{
"beginSection": "a... | 11 | BioASQ-training11b | null | null | 5c890ad575a4a5d21900000d | bioasq_factoid |
factoid | In which breast cancer patients can palbociclib be used? | [['hormone receptor-positive, human epidermal growth factor receptor 2-negative']] | [
"hormone receptor-positive, human epidermal growth factor receptor 2-negative",
"HR-positive, HER2-negative",
"hormone receptor-positive, HER2-negative",
"HR+/HER2-",
"estrogen receptor-positive, human epidermal growth factor receptor 2-negative",
"ER-positive, HER2-negative"
] | ['Palbociclib is useful for women with hormone receptor-positive, human epidermal growth factor receptor 2-negative breast cancer.'] | [
"http://www.ncbi.nlm.nih.gov/pubmed/26236140",
"http://www.ncbi.nlm.nih.gov/pubmed/25524798",
"http://www.ncbi.nlm.nih.gov/pubmed/25792301"
] | [
{
"beginSection": "abstract",
"document": "http://www.ncbi.nlm.nih.gov/pubmed/26236140",
"endSection": "abstract",
"offsetInBeginSection": 0,
"offsetInEndSection": 184,
"text": "Women with hormone receptor-positive, human epidermal growth factor receptor 2- negative breast cancer-the most co... | 5 | BioASQ-training5b | [
"http://www.nlm.nih.gov/cgi/mesh/2016/MB_cgi?field=uid&exact=Find+Exact+Term&term=D001943",
"http://www.disease-ontology.org/api/metadata/DOID:1612"
] | [] | 56d06e043975bb303a000011 | bioasq_factoid |
factoid | With which cancers has the loss of SMARCB1 been associated? | ['chordomas', 'childhood chordomas', 'infantile chordomas', 'CCs'] | [
"chordomas",
"childhood chordomas",
"infantile chordomas",
"CCs",
"chordoma"
] | ['Genotyping cancer-associated genes in chordoma identifies mutations in oncogenes and areas of chromosomal loss involving CDKN2A, PTEN, and SMARCB1 Loss of SMARCB1/INI1 expression is considered to be a hallmark for childhood chordomas (CCs)', 'We therefore sought to identify novel mutations to better understand chordo... | [
"http://www.ncbi.nlm.nih.gov/pubmed/28825187",
"http://www.ncbi.nlm.nih.gov/pubmed/28427232",
"http://www.ncbi.nlm.nih.gov/pubmed/27635948",
"http://www.ncbi.nlm.nih.gov/pubmed/24983247",
"http://www.ncbi.nlm.nih.gov/pubmed/28812319"
] | [
{
"beginSection": "abstract",
"document": "http://www.ncbi.nlm.nih.gov/pubmed/24983247",
"endSection": "abstract",
"offsetInBeginSection": 71,
"offsetInEndSection": 204,
"text": "We therefore sought to identify novel mutations to better understand chordoma biology and to potentially identify... | 11 | BioASQ-training11b | null | null | 5a86f074faa1ab7d2e00003a | bioasq_factoid |
factoid | What is the tradename of apixaban? | ['Eliquis'] | [
"Eliquis",
"Apixaban",
"Bristol-Myers Squibb",
"Eliquis (apixaban)"
] | ['The tradename of apixaban is Eliquis.'] | [
"http://www.ncbi.nlm.nih.gov/pubmed/23677804"
] | [
{
"beginSection": "abstract",
"document": "http://www.ncbi.nlm.nih.gov/pubmed/23677804",
"endSection": "abstract",
"offsetInBeginSection": 0,
"offsetInEndSection": 164,
"text": "The direct factor Xa inhibitor apixaban (Eliquis(®)) has predictable pharmacodynamics and pharmacokinetics and doe... | 11 | BioASQ-training11b | null | null | 5c920fc3ecadf2e73f000011 | bioasq_factoid |
factoid | Which receptor tyrosine kinase is commonly mutated or amplified in pediatric glioma cases? | ['PDGFRA', 'Platelet derived growth factor-alpha', 'Platelet derived growth factor-alpha (PDGFRA)'] | [
"PDGFRA",
"Platelet derived growth factor-alpha",
"Platelet derived growth factor-alpha (PDGFRA)",
"Platelet-derived growth factor receptor alpha",
"PDGF receptor alpha",
"PDGF receptor alpha chain",
"PDGF alpha receptor"
] | ['Pediatric high-grade glioma (pHGG), including both diffuse midline glioma (DMG) and non-midline tumors, continues to be one of the deadliest oncologic diagnoses. Targeted therapy options aimed at key oncogenic receptor tyrosine kinase (RTK) drivers using small-molecule RTK inhibitors have been extensively studied, bu... | [
"http://www.ncbi.nlm.nih.gov/pubmed/26727948",
"http://www.ncbi.nlm.nih.gov/pubmed/27582545",
"http://www.ncbi.nlm.nih.gov/pubmed/35978801",
"http://www.ncbi.nlm.nih.gov/pubmed/23970477",
"http://www.ncbi.nlm.nih.gov/pubmed/26744350",
"http://www.ncbi.nlm.nih.gov/pubmed/20479398",
"http://www.ncbi.nlm.n... | [
{
"beginSection": "abstract",
"document": "http://www.ncbi.nlm.nih.gov/pubmed/35978801",
"endSection": "abstract",
"offsetInBeginSection": 0,
"offsetInEndSection": 160,
"text": "Pediatric high-grade glioma (pHGG), including both diffuse midline glioma (DMG) and non-midline tumors, continues ... | 13 | BioASQ-training13b | null | null | 6630390b187cba990d000035 | bioasq_factoid |
yesno | Are PDXK mutations linked to polyneuropathy? | ['yes'] | [
"yes"
] | ['Yes, PDXK mutations are linked to polyneuropathy.', 'Yes, PDXK mutations are associated with autosomal recessive polyneuropathy.', "Yes. PDXK mutations cause polyneuropathy responsive to pyridoxal 5'-phosphate supplementation.", 'Yes, PDXK mutations are associated with delayed polyneuropathy.', 'Yes, point mutations ... | [
"http://www.ncbi.nlm.nih.gov/pubmed/31187503",
"http://www.ncbi.nlm.nih.gov/pubmed/32522499"
] | [
{
"beginSection": "title",
"document": "http://www.ncbi.nlm.nih.gov/pubmed/31187503",
"endSection": "title",
"offsetInBeginSection": 0,
"offsetInEndSection": 89,
"text": "PDXK mutations cause polyneuropathy responsive to pyridoxal 5'-phosphate supplementation."
},
{
"beginSection": "... | 11 | BioASQ-training11b | null | null | 6031002d1cb411341a000129 | bioasq_yesno |
factoid | Which is the literature-based database of phenotypes? | ['PheneBank'] | [
"PheneBank",
"PhenomeBank",
"Phene Bank"
] | ['PheneBank is a Web-portal for retrieving human phenotype-disease associations that have been text-mined from the whole of Medline. This approach exploits state-of-the-art machine learning for concept identification by utilising an expert annotated rare disease corpus from the PMC Text Mining subset. Evaluation of the... | [
"http://www.ncbi.nlm.nih.gov/pubmed/34788791"
] | [
{
"beginSection": "title",
"document": "http://www.ncbi.nlm.nih.gov/pubmed/34788791",
"endSection": "title",
"offsetInBeginSection": 0,
"offsetInEndSection": 53,
"text": "PheneBank: a literature-based database of phenotypes."
},
{
"beginSection": "abstract",
"document": "http://w... | 11 | BioASQ-training11b | null | null | 621e63a43a8413c653000051 | bioasq_factoid |
factoid | What is the mode of inheritance of Acromicric dysplasia? | ['autosomal dominant'] | [
"autosomal dominant",
"AD",
"autosomal dominant inheritance",
"dominant inheritance",
"dominant trait"
] | Acromicric dysplasia has an autosomal dominant mode of inheritance | [
"http://www.ncbi.nlm.nih.gov/pubmed/22791552",
"http://www.ncbi.nlm.nih.gov/pubmed/19396027",
"http://www.ncbi.nlm.nih.gov/pubmed/11694546"
] | [
{
"beginSection": "abstract",
"document": "http://www.ncbi.nlm.nih.gov/pubmed/22791552",
"endSection": "abstract",
"offsetInBeginSection": 696,
"offsetInEndSection": 840,
"text": "AD has an autosomal dominant mode of inheritance, distinct facial and skeleton features (a hoarse voice and inte... | 5 | BioASQ-training5b | [
"http://www.nlm.nih.gov/cgi/mesh/2014/MB_cgi?field=uid&exact=Find+Exact+Term&term=D040582",
"http://www.nlm.nih.gov/cgi/mesh/2014/MB_cgi?field=uid&exact=Find+Exact+Term&term=D001848"
] | [] | 53318685d6d3ac6a3400003d | bioasq_factoid |
yesno | Is phosphoenolpyruvate carboxykinase 1 (PCK1) the rate-limiting enzyme in gluconeogenesis? | ['yes'] | [
"yes"
] | ['Yes, Pck1 is a rate-limiting gluconeogenic enzyme, where its deficiency or mutation contributes to serious clinical situations as neonatal hypoglycemia and liver failure.'] | [
"http://www.ncbi.nlm.nih.gov/pubmed/31883179",
"http://www.ncbi.nlm.nih.gov/pubmed/31911238",
"http://www.ncbi.nlm.nih.gov/pubmed/32004540",
"http://www.ncbi.nlm.nih.gov/pubmed/32001301",
"http://www.ncbi.nlm.nih.gov/pubmed/32058049"
] | [
{
"beginSection": "abstract",
"document": "http://www.ncbi.nlm.nih.gov/pubmed/31911238",
"endSection": "abstract",
"offsetInBeginSection": 12,
"offsetInEndSection": 107,
"text": "Phosphoenolpyruvate carboxykinase (PEPCK) is a metabolic enzyme in the gluconeogenesis pathway,"
},
{
"be... | 11 | BioASQ-training11b | null | null | 6033f5541cb411341a00014c | bioasq_yesno |
factoid | What bacteria is associated with Gastric cancer and peptic ulcers? | ['helicobacter pylori'] | [
"Helicobacter pylori",
"H. pylori",
"Campylobacter pylori",
"Campylobacter mustelae",
"Helicobacter heilmannii"
] | ['Helicobacter pylori (H. pylori), a gram-negative microaerophilic bacterial pathogen that colonizes the stomachs of more than half of all humans, is linked to chronic gastritis, peptic ulcers and gastric cancer.', 'Peptic ulcer and gastric cancer are caused by the same bacteria, Helicobacter pylori.'] | [
"http://www.ncbi.nlm.nih.gov/pubmed/7886456",
"http://www.ncbi.nlm.nih.gov/pubmed/29764950",
"http://www.ncbi.nlm.nih.gov/pubmed/29432909",
"http://www.ncbi.nlm.nih.gov/pubmed/15610081",
"http://www.ncbi.nlm.nih.gov/pubmed/25539656",
"http://www.ncbi.nlm.nih.gov/pubmed/16583309",
"http://www.ncbi.nlm.ni... | [
{
"beginSection": "abstract",
"document": "http://www.ncbi.nlm.nih.gov/pubmed/29432909",
"endSection": "abstract",
"offsetInBeginSection": 0,
"offsetInEndSection": 229,
"text": "Helicobacter Pylori (H. pylori) is a gram-negative bacteria infecting numerous people all over the world. It has b... | 11 | BioASQ-training11b | null | null | 5e3c6c9eb5b409ea53000022 | bioasq_factoid |
factoid | What is the reason for the narcolepsy cases developed after H1N1 influenza vaccination? | ['The proposed mechanism for postvaccination narcolepsy is one in which an environmental trigger causes or enhances an antibody-mediated autoimmune response in patients with a preexisting genetic susceptibility.'] | [
"postvaccination narcolepsy",
"vaccination-induced narcolepsy",
"narcolepsy following vaccination",
"narcolepsy due to vaccination",
"autoimmune narcolepsy",
"antibody-mediated narcolepsy",
"genetic susceptibility narcolepsy",
"post-vaccination narcolepsy"
] | The proposed mechanism for postvaccination narcolepsy is one in which an environmental trigger causes or enhances an antibody-mediated autoimmune response in patients with a preexisting genetic susceptibility. | [
"http://www.ncbi.nlm.nih.gov/pubmed/24048081",
"http://www.ncbi.nlm.nih.gov/pubmed/23884811",
"http://www.ncbi.nlm.nih.gov/pubmed/23486871",
"http://www.ncbi.nlm.nih.gov/pubmed/22530521",
"http://www.ncbi.nlm.nih.gov/pubmed/22213222",
"http://www.ncbi.nlm.nih.gov/pubmed/21963829",
"http://www.ncbi.nlm.n... | [
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"text": "The proposed mechanism for postvaccination narcolepsy is one in which an environmental trigger causes or enhance... | 5 | BioASQ-training5b | [
"http://www.nlm.nih.gov/cgi/mesh/2014/MB_cgi?field=uid&exact=Find+Exact+Term&term=D009290",
"http://www.nlm.nih.gov/cgi/mesh/2014/MB_cgi?field=uid&exact=Find+Exact+Term&term=D053118",
"http://www.nlm.nih.gov/cgi/mesh/2014/MB_cgi?field=uid&exact=Find+Exact+Term&term=D014612",
"http://www.nlm.nih.gov/cgi/mesh/2... | [] | 530cf54dab4de4de0c000009 | bioasq_factoid |
factoid | What is the prognostic role of thyroid hormone in patients with heart failure? | ['There is a relationship between altered thyroid profile and mortality in patients with heart failure'] | [
"thyroid profile",
"thyroid function tests",
"thyroid hormone levels",
"altered thyroid profile",
"thyroid panel",
"thyroid tests",
"thyroid assessment",
"thyroid evaluation"
] | Altered thyroid profile, particularly sick euthyroid syndrome, is an independent predictor of mortality in patients with chronic heart failure, adding prognostic information to conventional clinical and functional cardiac parameters. | [
"http://www.ncbi.nlm.nih.gov/pubmed/20978564",
"http://www.ncbi.nlm.nih.gov/pubmed/22870736",
"http://www.ncbi.nlm.nih.gov/pubmed/19181292",
"http://www.ncbi.nlm.nih.gov/pubmed/19006851",
"http://www.ncbi.nlm.nih.gov/pubmed/15694896",
"http://www.ncbi.nlm.nih.gov/pubmed/15642542",
"http://www.ncbi.nlm.n... | [
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"document": "http://www.ncbi.nlm.nih.gov/pubmed/20978564",
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"text": " Cumulative survival was significantly lower among patients with free triiodothyronine < 2.12 pg/mL and among ... | 5 | BioASQ-training5b | [
"http://www.nlm.nih.gov/cgi/mesh/2014/MB_cgi?field=uid&exact=Find+Exact+Term&term=D005067",
"http://www.nlm.nih.gov/cgi/mesh/2014/MB_cgi?field=uid&exact=Find+Exact+Term&term=D006333",
"http://www.nlm.nih.gov/cgi/mesh/2014/MB_cgi?field=uid&exact=Find+Exact+Term&term=D013963",
"http://www.disease-ontology.org/a... | [] | 531b2fc3b166e2b80600003c | bioasq_factoid |
factoid | Which de novo mutation in FGFR cause achondroplasia? | ['G380R'] | [
"G380R",
"Gly380Arg",
"Glycine to Arginine at position 380",
"G380R mutation",
"G380R variant"
] | ['Recurrent missense mutations in a CpG doublet of the transmembrane domain of the FGFR3 protein (glycine substituted with arginine at residue 380, G380R).'] | [
"http://www.ncbi.nlm.nih.gov/pubmed/8078586"
] | [
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"document": "http://www.ncbi.nlm.nih.gov/pubmed/8078586",
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"text": "Achondroplasia, the most common cause of chondrodysplasia in man (1 in 15,000 live births), is a condition of unkn... | 11 | BioASQ-training11b | null | null | 5e2e11a1fbd6abf43b000021 | bioasq_factoid |
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