PMID uint64 | PMCID large_string | DOI large_string | Title large_string | Abstract large_string | Journal large_string | Year int64 | ISSN large_string | eISSN large_string | PMC_OA bool | Journal License large_string | IS_OA bool |
|---|---|---|---|---|---|---|---|---|---|---|---|
1 | null | 10.1016/0006-2944(75)90147-7 | Formate assay in body fluids: application in methanol poisoning. | null | Biochemical medicine | 1,975 | 0006-2944 | null | false | null | false |
2 | null | 10.1016/0006-291x(75)90482-9 | Delineation of the intimate details of the backbone conformation of pyridine nucleotide coenzymes in aqueous solution. | null | Biochemical and biophysical research communications | 1,975 | null | 1090-2104 | false | null | false |
3 | null | 10.1016/0006-291x(75)90498-2 | Metal substitutions incarbonic anhydrase: a halide ion probe study. | null | Biochemical and biophysical research communications | 1,975 | 0006-291X | null | false | null | false |
4 | null | 10.1016/0006-291x(75)90506-9 | Effect of chloroquine on cultured fibroblasts: release of lysosomal hydrolases and inhibition of their uptake. | null | Biochemical and biophysical research communications | 1,975 | null | 1090-2104 | false | null | false |
5 | null | 10.1016/0006-291x(75)90508-2 | Atomic models for the polypeptide backbones of myohemerythrin and hemerythrin. | null | Biochemical and biophysical research communications | 1,975 | null | 1090-2104 | false | null | false |
6 | null | 10.1016/0006-291x(75)90518-5 | Studies of oxygen binding energy to hemoglobin molecule. | null | Biochemical and biophysical research communications | 1,975 | 0006-291X | null | false | null | false |
7 | null | 10.1016/0006-2952(75)90020-9 | Maturation of the adrenal medulla--IV. Effects of morphine. | null | Biochemical pharmacology | 1,975 | null | 1873-2968 | false | null | false |
8 | null | 10.1016/0006-2952(75)90029-5 | Comparison between procaine and isocarboxazid metabolism in vitro by a liver microsomal amidase-esterase. | null | Biochemical pharmacology | 1,975 | null | 1873-2968 | false | null | false |
9 | null | 10.1016/0006-2952(75)90080-5 | Radiochemical assay of glutathione S-epoxide transferase and its enhancement by phenobarbital in rat liver in vivo. | null | Biochemical pharmacology | 1,975 | 0006-2952 | null | false | null | false |
10 | null | null | Digitoxin metabolism by rat liver microsomes. | null | Biochemical pharmacology | 1,975 | null | 1873-2968 | false | null | false |
11 | null | 10.1016/0006-2952(75)90001-5 | Identification of adenylate cyclase-coupled beta-adrenergic receptors with radiolabeled beta-adrenergic antagonists. | null | Biochemical pharmacology | 1,975 | 0006-2952 | null | false | null | false |
12 | null | 10.1016/0006-2952(75)90002-7 | The effect of adrenaline and of alpha- and beta-adrenergic blocking agents on ATP concentration and on incorporation of 32Pi into ATP in rat fat cells. | null | Biochemical pharmacology | 1,975 | 0006-2952 | null | false | null | false |
13 | null | 10.1016/0006-2952(75)90009-x | Action of propranolol on mitochondrial functions--effects on energized ion fluxes in the presence of valinomycin. | null | Biochemical pharmacology | 1,975 | 0006-2952 | null | false | null | false |
14 | null | 10.1016/0006-2952(75)90011-8 | Malathion A and B esterases of mouse liver-I. | null | Biochemical pharmacology | 1,975 | 0006-2952 | null | false | null | false |
15 | null | 10.1016/0006-2952(75)90013-1 | Increase in acetyl CoA synthetase activity after phenobarbital treatment. | null | Biochemical pharmacology | 1,975 | 0006-2952 | null | false | null | false |
16 | null | 10.1016/0006-2952(75)90016-7 | Inhibition of aldehyde reductase by acidic metabolites of the biogenic amines. | null | Biochemical pharmacology | 1,975 | 0006-2952 | null | false | null | false |
17 | null | 10.1016/0006-2952(75)90018-0 | Effects of 5,6-dihydroxytryptamine on tyrosine-hydroxylase activity in central catecholaminergic neurons of the rat. | null | Biochemical pharmacology | 1,975 | 0006-2952 | null | false | null | false |
18 | null | 10.1016/0006-2952(75)90405-0 | Inhibition of aldehyde reductase isoenzymes in human and rat brain. | null | Biochemical pharmacology | 1,975 | 0006-2952 | null | false | null | false |
19 | null | 10.1016/0006-2952(75)90412-8 | Antidepressant drugs affect dopamine uptake. | null | Biochemical pharmacology | 1,975 | 0006-2952 | null | false | null | false |
20 | null | 10.1016/0006-2952(75)90415-3 | Aggregation of blood platelets by adrenaline and its uptake. | null | Biochemical pharmacology | 1,975 | 0006-2952 | null | false | null | false |
21 | null | null | [Biochemical studies on camomile components/III. In vitro studies about the antipeptic activity of (--)-alpha-bisabolol (author's transl)]. | (--)-alpha-Bisabolol has a primary antipeptic action depending on dosage, which is not caused by an alteration of the pH-value. The proteolytic activity of pepsin is reduced by 50 percent through addition of bisabolol in the ratio of 1/0.5. The antipeptic action of bisabolol only occurs in case of direct contact. In ca... | Arzneimittel-Forschung | 1,975 | 0004-4172 | null | false | null | false |
22 | null | null | [Demonstration of tumor inhibiting properties of a strongly immunostimulating low-molecular weight substance. Comparative studies with ifosfamide on the immuno-labile DS carcinosarcoma. Stimulation of the autoimmune activity for approx. 20 days by BA 1, a N-(2-cyanoethylene)-urea. Novel prophylactic possibilities]. | A report is given on the recent discovery of outstanding immunological properties in BA 1 [N-(2-cyanoethylene)-urea] having a (low) molecular mass M = 111.104. Experiments in 214 DS carcinosarcoma bearing Wistar rats have shown that BA 1, at a dosage of only about 12 percent LD50 (150 mg kg) and negligible lethality (1... | Arzneimittel-Forschung | 1,975 | 0004-4172 | null | false | null | false |
23 | null | null | Effect of etafenone on total and regional myocardial blood flow. | The distribution of blood flow to the subendocardial, medium and subepicardial layers of the left ventricular free wall was studied in anaesthetized dogs under normoxic (A), hypoxic (B) conditions and under pharmacologically induced (etafenone) coronary vasodilation (C). Regional myocardial blood flow was determined by... | Arzneimittel-Forschung | 1,975 | 0004-4172 | null | false | null | false |
24 | null | null | Influence of a new virostatic compound on the induction of enzymes in rat liver. | The virostatic compound N,N-diethyl-4-[2-(2-oxo-3-tetradecyl-1-imidazolidinyl)-ethyl]-1-piperazinecarboxamide-hydrochloride (5531) was analyzed as to its effect on the induction of tryptophan-pyrrolase and tyrosineaminotransferase in rat liver. 1. The basic activity of the enzymes was not influenced by the substance ei... | Arzneimittel-Forschung | 1,975 | 0004-4172 | null | false | null | false |
25 | null | null | Pharmacological properties of new neuroleptic compounds. | RMI 61 140, RMI 61 144 and RMI 61 280 are newly synthetized N-[8-R-dibenzo(b,f)oxepin-10-yl]-N'-methyl-piperazine-maleates which show interesting psychopharmacologic effects. This work contains the results of a study performed with these three compounds, in order to demonstrate their neuropsycholeptic activity in compa... | Arzneimittel-Forschung | 1,975 | 0004-4172 | null | false | null | false |
26 | null | null | [Studies on the action of an anticholinergic agent in combination with a tranquilizer on gastric juice secretion in man]. | A double-blind study with intra-individual comparisons was carried out to investigate the effects of 15 mg of (8r)-3alpha-hydroxy-8-isopropyl-1alphaH-tropanium bromide(+/-)-tropate (Sch 1000), 15 mg Sch 1000 + 10 mg oxazepam, 10 mg oxazepam and placebo with oral administration in randomized sequence on gastric juice vo... | Arzneimittel-Forschung | 1,975 | 0004-4172 | null | false | null | false |
27 | null | null | Editorial: "Old lamps for new". | null | British journal of anaesthesia | 1,975 | 0007-0912 | null | false | null | false |
28 | null | 10.1093/bja/47.9.1033 | Letter: Duration of action of AH8165. | null | British journal of anaesthesia | 1,975 | 0007-0912 | null | false | null | false |
29 | null | null | Lorazepam in sexual disorders. | null | The British journal of clinical practice | 1,975 | 0007-0947 | null | false | null | false |
30 | null | 10.1111/j.1365-2133.1975.tb06468.x | Lysosomal hydrolases of the epidermis. I. Glycosidases. | Seven distinct glycosidases (EC 3.2) have been characterized in guinea-pig epidermis. Their properties indicate them to be of lysosomal origin. The 'profile' of the epidermal glycosidases is significantly different from that reported for whole skin, the activities of beta-galactosidase and beta-acetylglucosaminidase be... | The British journal of dermatology | 1,975 | 0007-0963 | null | false | null | false |
31 | null | 10.1111/j.1365-2133.1975.tb06512.x | Lysosomal hydrolases of the epidermis. 2. Ester hydrolases. | Five distinct ester hydrolases (EC 3-1) have been characterized in guinea-pig epidermis. These are carboxylic esterase, acid phosphatase, pyrophosphatase, and arylsulphatase A and B. Their properties are consistent with those of lysosomal enzymes. | The British journal of dermatology | 1,975 | 0007-0963 | null | false | null | false |
32 | null | 10.1111/j.1365-2141.1975.tb01808.x | A serum haemagglutinating property dependent upon polycarboxyl groups. | A serum agglutinin reactive with red cells in the presence of polycarboxyl groups is reported. It is likely that this represents an additional example of the type of agglutinin previously described as agglutinating red cells in the absence of ionized calcium. Experimental evidence is presented indicating that it is fre... | British journal of haematology | 1,975 | 0007-1048 | null | false | null | false |
33 | null | 10.1111/j.1365-2141.1975.tb01817.x | Effect of human erythrocyte stromata on complement activation. | Stroma from either normal or PNH-like red cells is capable of inhibiting, to some extent, lysis in the sucrose test and enhancing lysis in the acidified-serum test. The same opposing effects are displayed by the exclusion peaks from Sephadex G-200 obtained from each stroma preparation, suggesting that the same factor c... | British journal of haematology | 1,975 | 0007-1048 | null | false | null | false |
34 | null | 10.1111/j.1365-2141.1975.tb01833.x | Determinants of intracellular pH in the erythrocyte. | null | British journal of haematology | 1,975 | 0007-1048 | null | false | null | false |
35 | null | 10.1111/j.1365-2141.1975.tb00536.x | The effect of o-salicylate upon pentose phosphate pathway activity in normal and G6PD-deficient red cells. | The effect of the major metabolite of aspirin, namely salicylic acid, upon the pentose phosphate pathway (PPP) of normal and G6PD-deficient red cells has been studied. Salicylic acid was shown to inhibit this pathway in proportion to the amount present. At any concentration of this substance there was greater inhibitio... | British journal of haematology | 1,975 | 0007-1048 | null | false | null | false |
36 | null | 10.1017/s0007114575000530 | The effects of processing of barley-based supplements on rumen pH, rate of digestion of voluntary intake of dried grass in sheep. | 1. In one experiment the effect on rumen pH of feeding with restricted amounts of whole or pelleted barley was studied. With whole barley there was little variation in rumen pH associated with feeding time, but with pelleted barley the pH decreased from about 7-0 before feeding to about 5-3, 2--3 h after feeding. 2. Th... | The British journal of nutrition | 1,975 | 0007-1145 | null | false | null | false |
37 | null | 10.1021/bi00694a002 | Poly(8-aminoguanylic acid): formation of ordered self-structures and interaction with poly(cytidylic acid). | Poly(8-aminoguanylic acid) has in neutral solution a novel ordered structure of high stability. The 8-amino group permits formation of three hydrogen bonds between two residues along the "top", or long axis, of the purines. The usual hydrogen bonding protons and Watson-Crick pairing sites are not involved in the associ... | Biochemistry | 1,975 | 0006-2960 | null | false | null | false |
38 | null | 10.1021/bi00694a009 | Effect of pH on substrate and inhibitor kinetic constants of human liver alanine aminopeptidase. Evidence for two ionizable active center groups. | The presence of at least two ionizable active center groups has been detected by a study of the effect of pH upon catalysis of hydrolysis of L-alanyl-beta-naphthylamide by human liver alanine aminopeptidase and upon the inhibition of hydrolysis by inhibitors and substrate analogs. Octanoic acid, octylamine, and peptide... | Biochemistry | 1,975 | 0006-2960 | null | false | null | false |
39 | null | 10.1021/bi00694a011 | Formation of transient complexes in the glutamate dehydrogenase catalyzed reaction. | The reaction of glutamate dehydrogenase and glutamate (gl) with NAD+ and NADP+ has been studied with stopped-flow techniques. The enzyme was in all experiments present in excess of the coenzyme. The results indicate that the ternary complex (E-NAD(P)H-kg) is present as an intermediate in the formation of the stable com... | Biochemistry | 1,975 | 0006-2960 | null | false | null | false |
40 | null | 10.1021/bi00694a013 | Human brain and placental choline acetyltransferase: purification and properties. | Choline acetyltransferase (EC 2.3.1.6) catalyzes the biosynthesis of acetylcholine according to the following chemical equation: acetyl-CoA + choline in equilibrium to acetylcholine + CoA. In addition to nervous tissue, primate placenta is the only other animal source which contains appreciable acetylcholine and its bi... | Biochemistry | 1,975 | 0006-2960 | null | false | null | false |
41 | null | 10.1021/bi00694a018 | Stabilization of the globular structure of ferricytochrome c by chloride in acidic solvents. | Increasing concentrations of chloride were found to increase the resolution between two visible absorbance spectral transitions associated with acidification of ferricytochrome c. Analysis of a variety of spectral and viscosity measurements indicates that protonation of a single group having an apparent pK of 2.1 +/- 0... | Biochemistry | 1,975 | 0006-2960 | null | false | null | false |
42 | null | 10.1021/bi00694a023 | A competitive labeling method for the determination of the chemical properties of solitary functional groups in proteins. | The properties of the functional groups in a protein can be used as built-in-probes of the structure of the protein. We have developed a general procedure whereby the ionization constant and chemical reactivity of solitary functional groups in proteins may be determined. The method may be applied to the side chain of h... | Biochemistry | 1,975 | 0006-2960 | null | false | null | false |
43 | null | 10.1021/bi00694a027 | Modification of arginine and lysine in proteins with 2,4-pentanedione. | Primary amines react with 2,4-pentanedione at pH 6-9 to form enamines, N-alkyl-4-amino-3-penten-2-ones. The latter compounds readily regenerate the primary amine at low pH or on treatment with hydroxylamine. Guanidine and substituted guanidines react with 2,4-pentanedione to form N-substituted 2-amino-4,6-dimethylpyrim... | Biochemistry | 1,975 | 0006-2960 | null | false | null | false |
44 | null | 10.1021/bi00695a003 | The origin of the alkaline inactivation of pepsinogen. | Above pH 8.5, pepsinogen is converted into a form which cannot be activated to pepsin on exposure to low pH. Intermediate exposure to neutral pH, however, returns the protein to a form which can be activated. Evidence is presented for a reversible, small conformational change in the molecule, distinct from the unfoldin... | Biochemistry | 1,975 | 0006-2960 | null | false | null | false |
45 | null | 10.1021/bi00695a005 | Bovine liver dihydrofolate reductase: purification and properties of the enzyme. | A purification procedure is reported for obtaining bovine liver dihydrofolate reductase in high yield and amounts of 100-200 mg. A key step in the procedure is the use of an affinity gel prepared by coupling pteroyl-L-lysine to Sepharose. The purified reductase has a specific activity of about 100 units/mg and is homog... | Biochemistry | 1,975 | 0006-2960 | null | false | null | false |
46 | null | 10.1021/bi00695a006 | Purification and properties of Escherichia coli dihydrofolate reductase. | Dihydrofolate reductase has been purified 40-fold to apparent homogeneity from a trimethoprim-resistant strain of Escherichia coli (RT 500) using a procedure that includes methotrexate affinity column chromatography. Determinations of the molecular weight of the enzyme based on its amino acid composition, sedimentation... | Biochemistry | 1,975 | 0006-2960 | null | false | null | false |
47 | null | 10.1021/bi00695a007 | The influence of pH on the interaction of inhibitors with triosephosphate isomerase and determination of the pKa of the active-site carboxyl group. | Ionization effects on the binding of the potential transition state analogues 2-phosphoglycolate and 2-phosphoglycolohydroxamate appear to be attributable to the changing state of ionization of the ligands themselves, therefore it is unnecessary to postulate the additional involvement of an ionizing residue at the acti... | Biochemistry | 1,975 | 0006-2960 | null | false | null | false |
48 | null | 10.1021/bi00695a008 | Monoanion inhibition and 35Cl nuclear magnetic resonance studies of renal dipeptidase. | Kinetic analyses of monoanion inhibition and 15Cl nuclear magnetic resonance at 5.88 MHz were employed to study monoanion interactions with the zinc metalloenzyme, renal dipeptidase. The enzyme-catalyzed hydrolysis of glycyldehydrophenylalanine exhibited competitive inhibition when the reaction rate was determined in t... | Biochemistry | 1,975 | 0006-2960 | null | false | null | false |
49 | null | 10.1021/bi00695a010 | The interaction of bovine erythrocyte superoxide dismutase with hydrogen peroxide: inactivation of the enzyme. | Bovine erythrocyte superoxide dismutase was slowly and irreversibly inactivated by hydrogen peroxide. The rate of this inactivation was directly dependent upon the concentrations of both H2O2 and of enzyme, and its second-order rate constant at pH 10.0 and 25 degrees was 6.7 M-1 sec-1. Inactivation was preceded by a bl... | Biochemistry | 1,975 | 0006-2960 | null | false | null | false |
50 | null | 10.1021/bi00695a013 | Circular dichroism and fluorescence studies of homogeneous antibodies to type III pneumococcal polysaccharide. | The near-ultraviolet circular dichroism (CD) of three homogeneous anti-type III pneumococcal antibodies in the absence and the presence of the specific hexasaccharide ligand was studied. In addition recombinations and hybridizations of H and L chains derived from two of these antibodies were carried out and the CD spec... | Biochemistry | 1,975 | 0006-2960 | null | false | null | false |
51 | null | 10.1021/bi00695a014 | Conformational changes induced in a homogeneous anti-type III pneumococcal antibody by oligosaccharides of increasing size. | The circular polarization of luminescence (CPL) emitted by tryptophan residues was used as a sensitive probe for measuring ligand-induced structural changes in a homogeneous type III pneumococcal antibody. A series of oligosaccharide ligands of increasing size derived from type III polysaccharide by partial acid hydrol... | Biochemistry | 1,975 | 0006-2960 | null | false | null | false |
52 | null | 10.1021/bi00695a016 | Evidence of the involvement of a 50S ribosomal protein in several active sites. | The functional role of the Bacillus stearothermophilus 50S ribosomal protein B-L3 (probably homologous to the Escherichia coli protein L2) was examined by chemical modification. The complex [B-L3-23S RNA] was photooxidized in the presence of rose bengal and the modified protein incorporated by reconstitution into 50S r... | Biochemistry | 1,975 | 0006-2960 | null | false | null | false |
53 | null | 10.1021/bi00696a001 | The interaction of phospholipase A2 with micellar interfaces. The role of the N-terminal region. | The localization of the previously postulated interface recognition site (IRS) in porcine pancreatic phospholipase A2, required for a specific interaction between the enzyme and organized lipid-water interfaces, was investigated by ultraviolet difference spectroscopy, by measurements of the intrinsic fluorescence of th... | Biochemistry | 1,975 | 0006-2960 | null | false | null | false |
54 | null | 10.1021/bi00696a003 | Phospholipase A2 as a probe of phospholipid distribution in erythrocyte membranes. Factors influencing the apparent specificity of the reaction. | The action of snake venom phospholipases A2 in intact human erythrocytes was investigated in detail. The basis phospholipase from Agkistrodon halys blomhifii was found to induce both hydrolysis of membrane phospholipids and total cell hemolysis under certain experimental conditions. The hydrolytic action of the basic e... | Biochemistry | 1,975 | 0006-2960 | null | false | null | false |
55 | null | 10.1021/bi00696a008 | Subunit interactions in yeast glyceraldehyde-3-phosphate dehydrogenase. | The spontaneous inactivation of yeast glyceraldehyde-3-phosphate dehydrogenase was found to fit a simple two-state model at pH 8.5 and 25 degrees. The first step is a relatively rapid dissociation of the tetramer to dimers with the equilibrium largely in favor of the tetramer. In the absence of NAD+ the dimer inactivat... | Biochemistry | 1,975 | 0006-2960 | null | false | null | false |
56 | null | 10.1021/bi00696a012 | Kinetic light scattering studies on the dissociation of hemoglobin from Lumbricus terrestris. | The kinetics of the pH-induced dissociation of the 3 X 10(6) mol wt hemoglobin from Lumbricus terrestris (the earthworm) have been studied in a light-scattering stopped-flow apparatus. The ligand dependent dissociation data were fit well by a simple sequential model. The data for CO and oxyhemoglobin are consistent wit... | Biochemistry | 1,975 | 0006-2960 | null | false | null | false |
57 | null | 10.1021/bi00696a014 | The reversible reduction of horse metmyoglobin by the iron(II) complex of trans-1,2-diaminocyclohexane-N,N,N,n-tetraacetate. | The reduction of metmyoglobin by the iron(II) complex of trans-1,2-diaminocyclohexane-N,N,N'N'-tetraacetate (FeCDTA2-) has been investigated. The equilibrium constant, measured spectrophotometrically, is 0.21 with a resulting reduction potential of 0.050 V for Mb0. The rate constant for the reduction is 28 M-1 sec-1 wi... | Biochemistry | 1,975 | 0006-2960 | null | false | null | false |
58 | null | 10.1021/bi00696a019 | Constitution and properties of axonal membranes of crustacean nerves. | The purification of axonal membranes of crustaceans was followed by measuring enrichment in [3H]tetrodotoxin binding capacity and in Na+, K+-ATPase activity. A characteristic of these membranes is their high content of lipids and their low content of protein as compared to other types of plasmatic membranes. The axonal... | Biochemistry | 1,975 | 0006-2960 | null | false | null | false |
59 | null | 10.1016/0005-2728(75)90002-x | Regulation of nitrogen fixation. Nitrogenase-derepressed mutants of Klebsiella pneumoniae. | 1. A new procedure is described for selecting nitrogenase-derepressed mutants based on the method of Brenchley et al. (Brenchley, J.E., Prival, M.J. and Magasanik, B. (1973) J. Biol. Chem. 248, 6122-6128) for isolating histidase-constitutive mutants of a non-N2-fixing bacterium. 2. Nitrogenase levels of the new mutants... | Biochimica et biophysica acta | 1,975 | 0006-3002 | null | false | null | false |
60 | null | 10.1016/0005-2728(75)90124-3 | The reaction between the superoxide anion radical and cytochrome c. | 1. The superoxide anion radical (O2-) reacts with ferricytochrome c to form ferrocytochrome c. No intermediate complexes are observable. No reaction could be detected between O2- and ferrocytochrome c. 2. At 20 degrees C the rate constant for the reaction at pH 4.7 to 6.7 is 1.4-10(6) M-1. S -1 and as the pH increases ... | Biochimica et biophysica acta | 1,975 | 0006-3002 | null | false | null | false |
61 | null | 10.1016/0005-2728(75)90129-2 | Identification of the 120 mus phase in the decay of delayed fluorescence in spinach chloroplasts and subchloroplast particles as the intrinsic back reaction. The dependence of the level of this phase on the thylakoids internal pH. | After a 500 mus laser flash a 120 mus phase in the decay of delayed fluorescence is visible under a variety of circumstances in spinach chloroplasts and subchloroplast particles enriched in Photosystem II prepared by means of digitonin. The level of this phase is high in the case of inhibition of oxygen evolution at th... | Biochimica et biophysica acta | 1,975 | 0006-3002 | null | false | null | false |
62 | null | 10.1016/0005-2728(75)90134-6 | Light-induced changes of absorbance and electron spin resonance in small photosystem II particles. | Photosystem II reaction center components have been studied in small system II particles prepared with digitonin. Upon illumination the reduction of the primary acceptor was indicated by absorbance changes due to the reduction of a plastoquinone to the semiquinone anion and by a small blue shifts of absorption bands ne... | Biochimica et biophysica acta | 1,975 | 0006-3002 | null | false | null | false |
63 | null | 10.1016/0005-2760(75)90151-4 | Enzymic reactions of fatty acid hydroperoxides in extracts of potato tuber. II. Conversion of 9- and 13-hydroperoxy-octadecadienoic acids to monohydroxydienoic acid, epoxyhydroxy- and trihydroxymonoenoic acid derivatives. | 1. Crude extracts and partially purified enzyme preparations from potato tubers catalyse, at pH 5-7, the conversion of linoleic acid hydroperoxides to a range of oxygenated fatty acid derivatives. 2. 9-D- and 13-L-hydroperoxide isomers are converted at similar rates to equivalent (isomeric) products. 3. The major produ... | Biochimica et biophysica acta | 1,975 | 0006-3002 | null | false | null | false |
64 | null | 10.1016/0005-2760(75)90154-x | Partial purification and properties of microsomal phosphatidate phosphohydrolase from rat liver. | Microsomal phosphatidate phosphohydrolase (phosphatidate phosphatase EC 3.1.3.4) was solubilized and fractionated to yield at least two distinct enzymatically active fractions. One, denoted FA, was non-specific, had a relatively high Km for phosphatidic acid and was insensitive to inhibition by diacylglycerol. The seco... | Biochimica et biophysica acta | 1,975 | 0006-3002 | null | false | null | false |
65 | null | 10.1016/0005-2760(75)90159-9 | Bile acids. XLVII. 12alpha-Hydroxylation of precursors of allo bile acids by rabbit liver microsomes. | Rabbit liver microsomal preparations fortified with 0.1 mM NADPH effectively promote hydroxylation of [3beta-3H]- or [24-14C]allochenodeoxycholic acid or [5alpha,6alpha-3H2]5alpha-cholestane-3alpha,7alpha-diol to their respective 12alpha-hydroxyl derivatives in yields of about 25 or 65% in 60 min. Minor amounts of othe... | Biochimica et biophysica acta | 1,975 | 0006-3002 | null | false | null | false |
66 | null | 10.1016/0005-2744(75)90202-8 | Partial purification and properties of a phenobarbital-induced aldehyde dehydrogenase of rat liver. | Properties of the phenobarbital induced cytoplasmic aldehyde dehydrogenase (EC 1.2.1.3) have been studied in rat liver. 7-12-Fold higher levels were seen in the cytoplasmic activities after phenobarbital treatment in reactor compared to non-reactor animals with high concentrations of acetaldehyde (18 mM) and propionald... | Biochimica et biophysica acta | 1,975 | 0006-3002 | null | false | null | false |
67 | null | 10.1016/0005-2744(75)90213-2 | Cholinesterases from plant tissues. VI. Preliminary characterization of enzymes from Solanum melongena L. and Zea mays L. | Enzymes capable of hydrolyzing esters of thiocholine have been assayed in extracts of Solanum melongena L. (eggplant) and Zea Mays L. (corn). The enzymes from both species are inhibited by the anti-cholinesterases neostigmine, physostigmine, and 284c51 and by AMO-1618, a plant growth retardant and they both have pH opt... | Biochimica et biophysica acta | 1,975 | 0006-3002 | null | false | null | false |
68 | null | 10.1016/0005-2744(75)90214-4 | Behavior of soluble and immobilized acid phosphatase in hydro-organic media. | The hydrolysis of p-nitrophenyl phosphate by wheat germ acid phosphatase (orthophosphoric monoester phosphohydrolase, EC 3.1.3.2) has been investigated in mixtures of aqueous buffers with acetone, dioxane and acetonitrile. The enzyme was either in free solution or immobilized on a pellicular support which consisted of ... | Biochimica et biophysica acta | 1,975 | 0006-3002 | null | false | null | false |
69 | null | 10.1016/0005-2744(75)90215-6 | Purification and some enzymatic properties of the chitosanase from Bacillus R-4 which lyses Rhizopus cell walls. | A strain of Bacillus sp (Bacillus R-4) produces a protease and a carbohydrolase both of which have the ability to lyse Rhizopus cell walls. Of the enzymes, the carbohydrolase has been purified to an ultracentrifugally and electrophoretically homogeneous state, and identified as a chitosanase. The enzyme was active on g... | Biochimica et biophysica acta | 1,975 | 0006-3002 | null | false | null | false |
70 | null | 10.1016/0005-2744(75)90216-8 | Specificity studies on alpha-mannosidases using oligosaccharides from mannosidosis urine as substrates. | Oligosaccharides containing terminal non-reducing alpha(1 leads to 2)-, alpha(1 leads to 3)-, and alpha(1 leads to 6)-linked mannose residues, isolated from human and bovine mannosidosis urines were used as substrates to test the specificities of acidic alpha-mannosidases isolated from human and bovine liver. The enzym... | Biochimica et biophysica acta | 1,975 | 0006-3002 | null | false | null | false |
71 | null | 10.1016/0005-2744(75)90218-1 | Calcium-stimulated adenosine triphosphatase in the microsomal fraction of tooth germ from porcine fetus. | The characterization and localization of a Ca(2+)-ATPase (ATP phosphohydrolase, EC 3.6.1.3) in the tooth germ of the porcine fetus are reported. This enzyme, a microsome fraction, is preferentially activated by Ca(2+). In the presence of 0.5 mM ATP, maximal enzyme activity is obtained at 0.5--1.0 mM CaCl2. The maximal ... | Biochimica et biophysica acta | 1,975 | 0006-3002 | null | false | null | false |
72 | null | 10.1016/0005-2744(75)90219-3 | Preparation and characterization of an enzymatically active immobilized derivative of myosin. | Purified skeletal muscle myosin (EC 3.6.1.3) has been covalently bound to Sepharose 4B by the cyanogen bromide procedure. The resulting complex, Sepharose-Myosin, possesses adenosine triphosphatase activity and is relatively stable for long periods of time. Under optimal binding conditions, approximately 33% of the spe... | Biochimica et biophysica acta | 1,975 | 0006-3002 | null | false | null | false |
73 | null | 10.1016/0005-2744(75)90220-x | Radioactive labeling and location of specific thiol groups in myosin from fast, slow and cardiac muscles. | 1. Based on incorporation of radioactively labeled N-ethylmaleimide, the readily reactive thiol groups of isolated myosin (EC 3.6.1.3) from fast, slow and cardiac muscles could be classified into 3 types. All 3 myosins contain 2 thiol-1, 2 thiol-2 and a variable number of thiol-3 groups per molecule. Both thiol-1 and t... | Biochimica et biophysica acta | 1,975 | 0006-3002 | null | false | null | false |
74 | null | 10.1016/0005-2744(75)90204-1 | Yeast glutathione reductase. Studies of the kinetics and stability of the enzyme as a function of pH and salt concentration. | 1. The pH dependencies of the apparent Michaelis constant for oxidized glutathione and the apparent turnover number of yeast glutathione reductase (EC 1.6.4.2) have been determined at a fixed concentration of 0.1 mM NADPH in the range pH 4.5--8.0. Between pH 5.5 and 7.6, both of these parameters are relatively constant... | Biochimica et biophysica acta | 1,975 | 0006-3002 | null | false | null | false |
75 | null | 10.1016/0005-2744(75)90206-5 | Characteristics of the dephosphorylated form of phosphorylase purified from rat liver and measurement of its activity in crude liver preparations. | The phosphorylated form of liver glycogen phosphorylase (alpha-1,4-glucan : orthophosphate alpha-glucosyl-transferase, EC 2.4.1.1) (phosphorylase a) is active and easily measured while the dephosphorylated form (phosphorylase b), in contrast to the muscle enzyme, has been reported to be essentially inactive even in the... | Biochimica et biophysica acta | 1,975 | 0006-3002 | null | false | null | false |
76 | null | 10.1016/0005-2744(75)90209-0 | Multiple forms of casein kinase from rabbit erythrocytes. | Two rabbit erythrocyte casein kinases, GTP:casein kinase I and GTP:casein kinase II, have been purified 29 000- and 47 000-fold, respectively. Studies employing sucrose density gradient centrifugation indicate that kinase I has a molecular weight of about 9.5 - 10(5) (25 S) and kinase II about 1.4 - 10(6) (32 S). These... | Biochimica et biophysica acta | 1,975 | 0006-3002 | null | false | null | false |
77 | null | 10.1016/0005-2744(75)90210-7 | Kinetic studies and effects of anions on creatine phosphokinase from skeletal muscle of rhesus monkey (Macaca mulatta). | A purification procedure for creatine kinase (EC 2.7.3.2) from muscle of the monke35--170 muequiv H+/mg protein per min at 30 degrees C and a yield of approx. 0.5 g/kg muscle. Assuming equilibrium kinetics, synergistic binding of substrates at one catalytic site is found for both the forward and back reactions. Kinetic... | Biochimica et biophysica acta | 1,975 | 0006-3002 | null | false | null | false |
78 | null | 10.1016/0304-4165(75)90310-4 | Studies on rat renal cortical cell kallikrein. I. Separation and measurement. | A technique has been developed to separate and measure kallikrein in a heterogeneous population of rat renal cortical cells in suspension. After rat kidneys were perfused in situ in anaesthetized rats, viable, counted cortical cell suspensions were obtained. Cells were suspended in a sucrose/Tris buffer containing 0.5%... | Biochimica et biophysica acta | 1,975 | 0006-3002 | null | false | null | false |
79 | null | 10.1016/0005-2795(75)90348-7 | Studies on electron transfer between mercury electrode and hemoprotein. | The electrochemical behaviour of ferricytochrome c, metmyoglobin and methemoglobin was studied using d.c., a.c. and differential pulse polarography, and controlled potential electrolysis. 1. The three hemoproteins yield d.c. polarographic steps, and peaks in differential pulse polarograms, the height of which is propor... | Biochimica et biophysica acta | 1,975 | 0006-3002 | null | false | null | false |
80 | null | 10.1016/0005-2795(75)90349-9 | The binding of organic phosphates to human methaemoglobin A. Perturbation of the polymerization of proteins by effectors. | Theory is presented relating to the binding of an effector to two states of a protein acceptor coexisting in equilibrium. The problem is treated in terms of the four possible cases which specify relations between numbers of binding sites and intrinsic binding constants relevant to the acceptor states. It is shown that ... | Biochimica et biophysica acta | 1,975 | 0006-3002 | null | false | null | false |
81 | null | 10.1016/0005-2795(75)90351-7 | N-terminal spin label studies of hemoglobin, Ligand and pH dependence. | Human hemoglobin was spin labeled with 4-isothiocanato-2,2,6,6-tetramethyl-piperdinooxyl, which is known to bind specifically to the N-terminal alpha-amino groups of proteins and slightly to the reactive sulfhydryl groups. Electron spin resonance (ESR) analysis indicated a partially resolved five-line spectrum, suggest... | Biochimica et biophysica acta | 1,975 | 0006-3002 | null | false | null | false |
82 | null | 10.1016/0005-2795(75)90336-0 | The behavior of holo- and apo-forms of bovine superoxide dismutase at low pH. | 1. Holo-superoxide dismutase from bovine erythrocytes has been shown to undergo a reversible structural modification in the pH 3-5 range. 2. The spectral alterations observed on changing from neutrality to pH 2 were: a slight attenuation of the 680 nm absorbance; the loss of the 450 nm shoulder, apparent in the optical... | Biochimica et biophysica acta | 1,975 | 0006-3002 | null | false | null | false |
83 | null | 10.1016/0005-2795(75)90034-3 | Mechanical precipitation of hemoglobin köln. | Hb Köln (beta 98 Val leads to Met) was found to precipitate rapidly during mechanical shaking. The rate of precipitation of Hb Köln is 5-6 times faster than that of Hb S. The kinetics of precipitation of the patient's hemolysate, which is a mixture of Hb Köln and Hb A, showed a biphasic curve indicating that Hb Köln pr... | Biochimica et biophysica acta | 1,975 | 0006-3002 | null | false | null | false |
84 | null | 10.1016/0005-2795(75)90035-5 | Physical properties and subunits of Haemopis grandis erythrocruorin. | The erythrocruorin of the leech Haemopis grandis possessed an S20,w of 57 S at neutral pH, its isoelectric point at pH 6.0 and exhibited a slightly sigmoid oxygenation curve with n approximately 2.1 and P50 = 11.2 mm at pH 7.4. A minimum molecular weight of 24000 +/- 1500 per heme group was determined from the iron and... | Biochimica et biophysica acta | 1,975 | 0006-3002 | null | false | null | false |
85 | null | 10.1016/0005-2795(75)90038-0 | Myosin from arterial smooth muscle: isolation following actin depolymerization. | The contractile proteins from arterial smooth muscle are highly soluble, and can be extracted at I = 0.05. However, they can be precipitated by a prolonged dialysis at pH 6 to give an actomyosin with a high, although variable, actin:myosin ratio. The sedimentation behavior of this actomyosin at high ionic strength was ... | Biochimica et biophysica acta | 1,975 | 0006-3002 | null | false | null | false |
86 | null | 10.1016/0005-2795(75)90040-9 | Hybrids of chemical derivatives of Escherichia coli alkaline phosphatase. | The activities of hybrid dimers of alkaline phosphatase containing two chemically modified subunits have been investigated. One hybrid species was prepared by dissociation and reconstitution of a mixture of two variants produced by chemical modification of the native enzyme with succinic anhydride and tetranitromethane... | Biochimica et biophysica acta | 1,975 | 0006-3002 | null | false | null | false |
87 | null | 10.1016/0005-2795(75)90042-2 | Some physicochemical properties of hemoglobin-manitoba (alpha2 102Ser replaced by Arg (G9) beta2). | Hb-Manitoba was discovered in 1970 [1] in a Canadian family of British origin. Recently we observed the same variant in a second family, and found that the oxy-derivative of Hb-Manitoba is slightly unstable at 65 degrees C, dissociates less readily at alkaline pH than does Hb-A, and forms asymmetric hybrids with other ... | Biochimica et biophysica acta | 1,975 | 0006-3002 | null | false | null | false |
88 | null | 10.1016/0005-2795(75)90043-4 | The oxygen affinity of haemoglobin Tak, a variant with an elongated beta chain. | The oxygen affinity was investigated of purified Hb Tak, a human haemoglobin variant with elongated beta-chains. A very low P50 value was found which was not influenced by the addition of 2,3 diphosphoglycerate. The n value was 1, indicating non-cooperativity. The oxygen equilibrium curve of the whole blood haemolysate... | Biochimica et biophysica acta | 1,975 | 0006-3002 | null | false | null | false |
89 | null | 10.1016/0005-2736(75)90064-4 | Effects of membrane ribonuclease and 3'-nucleotidase on the digestion of polyuridylic acid by rat liver plasma membrane. | 1. Fragments of isolated rat liver plasma membrane possess a ribonuclease activity which at pH 7.8 in the presence of 10 mM EDTA can digest polyuridylic acid (poly(U)) and polycytidylic acid (poly(C)) but not polyadenylic acid (poly(A)) and polyguanylic acid (poly(G)). Under these conditions, the membrane preparation d... | Biochimica et biophysica acta | 1,975 | 0006-3002 | null | false | null | false |
90 | null | 10.1016/0005-2736(75)90065-6 | Alterations in phospholipid-dependent (Na+ +K+)-ATPase activity due to lipid fluidity. Effects of cholesterol and Mg2+. | The (Na+ +K+)-activated, Mg2+-dependent ATPase from rabbit kidney outer medulla was prepared in a partially inactivated, soluble form depleted of endogenous phospholipids, using deoxycholate. This preparation was reactivated 10 to 50-fold by sonicated liposomes of phosphatidylserine, but not by non-sonicated phosphatid... | Biochimica et biophysica acta | 1,975 | 0006-3002 | null | false | null | false |
91 | null | 10.1016/0005-2736(75)90123-6 | Conformational and molecular responses to pH variation of the purified membrane adenosine triphosphatase of Micrococcus lysodeikticus. | A preparation of ATPase from the membranes of Micrococcus lysodeikticus, solubilized and more than 95% pure, showed two main bands in analytical polyacrylamide gel electrophoresis. They did not correspond to isoenzymes because one band could be converted into the other by exposure to a mildly alkaline pH value. The con... | Biochimica et biophysica acta | 1,975 | 0006-3002 | null | false | null | false |
92 | null | 10.1016/0005-2736(75)90130-3 | Membrane-bound enzymes. III. Protease activity in leucocytes in relation to erythrocyte membranes. | Protease activity was detected in membranes of human bovine erythrocytes prepared by the conventional procedures which include washing and removal of the "buffy layer". The enzyme was extracted by 0.75 M KCNS or (NH4)2SO4 and was activated by 0.4 to 0.5 M of the same salts. Colored, particulate hide powder-azure, memb... | Biochimica et biophysica acta | 1,975 | 0006-3002 | null | false | null | false |
93 | null | null | [Structure formation in interphase adsorption layers of lysozyme at liquid boundaries]. | In connection with the modelling of biomembranes regularities of the formation and development of interphase adsorption layers of lysozyme at liquid borders under different conditions and depending on the nature of carbohydrate phase were investigated by the determination of mechanical characteristics of such layers. T... | Biofizika | null | 0006-3029 | null | false | null | false |
94 | null | null | [Relation between fluorescence and circular dichroism of the complex of the fluorescence probe 4-dimethylaminochalcone with serum albumin]. | The fluorescence probe(4-dimethylaminochalcone; DMH) was noncovalently linked to human serum albumin (HSA). The variation of pH was due to serum albumin structural changes, which was determined in terms of DMH and HSA fluorescence and CD spectra. Considerable changes of fluorescence and CD spectra were observed at pH 8... | Biofizika | null | 0006-3029 | null | false | null | false |
95 | null | null | [Luminescence study of the effect of temperature on the conformational state of fibrinogen]. | Results are presented of measuring fibrinogen fluorescence parameters in temperature range of 20-80 degrees C at different pH of the solution. It was found that the temperature increase from 20 to 40 degrees C for solutions with pH of 4,5-9,3 were not accompanied by the conformational changes of fibrinogen macromolecul... | Biofizika | null | 0006-3029 | null | false | null | false |
96 | null | 10.1016/0301-4622(75)80025-1 | Polymer concentration dependence of the helix to random coil transition of a charged polypeptide in aqueous salt solution. | The helix to coil transition of poly(L-glutamic acid) was investigated in 0.05 and 0.005 M aqueous potassium chloride solutions by use of potentiometric titration and circular dichroism measurement. Polymer concentration dependence of the transition was observed in the range from 0.006 to 0.04 monomol/e in 0.005 M KG1 ... | Biophysical chemistry | 1,975 | 0301-4622 | null | false | null | false |
97 | null | null | Hydrogen peroxide and iron: a microbial cellulolytic system? | null | Biotechnology and bioengineering symposium | 1,975 | 0572-6565 | null | false | null | false |
98 | null | null | Microbial sources of cellulase. | null | Biotechnology and bioengineering symposium | 1,975 | 0572-6565 | null | false | null | false |
99 | null | null | Mannosidosis: clinical and biochemical findings. | null | Birth defects original article series | 1,975 | 0547-6844 | null | false | null | false |
100 | null | null | Bovine mannosidosis--a model lysosomal storage disease. | null | Birth defects original article series | 1,975 | 0547-6844 | null | false | null | false |
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PubMed / PubMedCentral metadata I've collected. I produced this by downloading the baselines for PubMed / PubMedCentral from their FTP servers, yet some of the abstracts are strangely truncated. Not sure what is going on there.
IS_OA indicates if the paper is open access, and this was determined by using the data from https://doaj.org/. PMC_OA indicates if its in the PMC open access set.
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