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157 | 1 | Mechanisms of glycolytic inhibition in ischemic rat hearts. | MEDLINE | Manual | NLM | The mechanisms of glycolytic inhibition in ischemic myocardium were investigated in the isolated, perfused rat heart. Glycolysis was inhibited at the level of glyceraldehyde-3-phosphate dehydrogenase. The major factors that accounted for the glycolytic inhibition in the ischemic heart compared with the anoxic heart app... | Circulation research | 0009-7330 | Print | 37 | 6 | Print | 1,975 | Dec | null | 742-51 | M J Rovetto (MJ); W F Lamberton (WF); J R Neely (JR) | Journal Article (D016428); Research Support, U.S. Gov't, P.H.S. (D013487) | Insulin (Registry: 0, UI: D007328); Lactates (Registry: 0, UI: D007773); Glucose (Registry: IY9XDZ35W2, UI: D005947) | Animals (UI: D000818, Major: No); Blood Flow Velocity (UI: D001783, Major: No); Coronary Circulation (UI: D003326, Major: Yes); Coronary Disease (UI: D003327, Major: No) - Qualifiers: metabolism (UI: Q000378, Major: Yes); Extracellular Space (UI: D005110, Major: No); Glucose (UI: D005947, Major: No) - Qualifiers: admin... | Animals|Blood Flow Velocity|Coronary Circulation|Coronary Disease|Extracellular Space|Glucose|Glycolysis|Heart|Hydrogen-Ion Concentration|In Vitro Techniques|Insulin|Intracellular Fluid|Lactates|Male|Myocardium|Perfusion|Rats | |||metabolism (1)||administration & dosage (0)|||||administration & dosage (0)||pharmacology (0)||metabolism (1)|| | 0|0|1|0|0|0|1|0|0|0|0|0|0|0|0|0|0 | null | 1976-02-26 | 2019-07-06 | pubmed: 1975-12-1; medline: 1975-12-1 0:1; entrez: 1975-12-1 0:0 | pubmed: 157; doi: 10.1161/01.res.37.6.742 | Myocardial Ischemia | ['Coronary Disease'] |
404 | 1 | Arterialization of the coronary veins in diffuse coronary arteriosclerosis. | MEDLINE | Manual | NLM | Since the coronary veins and capillaries are not involved with arteriosclerotic disease the authors performed experimental, and afterwards, clinical total and selective coronary vein arterialization. Acute myocardial ischaemia created for instance by ligation of the anterior descending branch, was treated by an interna... | The Journal of cardiovascular surgery | 0021-9509 | Print | 16 | 5 | Print | null | null | null | 520-5 | J W Moll (JW); A J Dziatkowiak (AJ); M Edelman (M); W Iljin (W); E Ratajczyk-Pakalska (E); K Stengert (K) | Journal Article (D016428) | null | Adult (UI: D000328, Major: No); Aged (UI: D000368, Major: No); Coronary Disease (UI: D003327, Major: No) - Qualifiers: surgery (UI: Q000601, Major: Yes); Coronary Vessels (UI: D003331, Major: No) - Qualifiers: surgery (UI: Q000601, Major: Yes); Female (UI: D005260, Major: No); Follow-Up Studies (UI: D005500, Major: No)... | Adult|Aged|Coronary Disease|Coronary Vessels|Female|Follow-Up Studies|Humans|Male|Methods|Middle Aged|Myocardial Revascularization|Veins | ||surgery (1)|surgery (1)||||||||surgery (0) | 0|0|0|0|0|0|0|0|0|0|0|0 | null | 1976-02-09 | 2023-08-15 | pubmed: 1975-9-1; medline: 1975-9-1 0:1; entrez: 1975-9-1 0:0 | pubmed: 404 | Myocardial Ischemia | ['Coronary Disease'] |
480 | 1 | Recognition and significance of maternogenic fetal acidosis during intensive monitoring of labor. | MEDLINE | Manual | NLM | FHR monitoring and microanalysis of fetal blood are mutually complementary procedures, and optimal knowledge of the fetal state is achieved by making use of both, the former for the preliminary screening of all cases at risk and the latter for the purpose of deciding on obstetric management where pathological changes a... | Journal of perinatal medicine | 0300-5577 | Print | 3 | 1 | Print | 1,975 | null | null | 53-67 | G D Roversi (GD); V Canussio (V); M Spennacchio (M) | Journal Article (D016428) | Hemoglobins (Registry: 0, UI: D006454) | Acid-Base Equilibrium (UI: D000136, Major: No); Acidosis (UI: D000138, Major: No) - Qualifiers: diagnosis (UI: Q000175, Major: Yes); Apgar Score (UI: D001034, Major: No); Bradycardia (UI: D001919, Major: No) - Qualifiers: diagnosis (UI: Q000175, Major: No); Electrocardiography (UI: D004562, Major: No) - Qualifiers: met... | Acid-Base Equilibrium|Acidosis|Apgar Score|Bradycardia|Electrocardiography|Female|Fetal Distress|Fetal Heart|Heart Rate|Hemoglobins|Humans|Hydrogen-Ion Concentration|Infant, Newborn|Maternal-Fetal Exchange|Monitoring, Physiologic|Obstetric Labor Complications|Pregnancy|Uterine Contraction | |diagnosis (1)||diagnosis (0)|methods (0)||diagnosis (1)|physiopathology (0)||||||||diagnosis (1)|| | 0|0|0|0|0|0|0|0|0|0|0|0|0|1|0|0|0|0 | null | 1976-02-19 | 2019-09-18 | pubmed: 1975-1-1; medline: 1975-1-1 0:1; entrez: 1975-1-1 0:0 | pubmed: 480; doi: 10.1515/jpme.1975.3.1.53 | Arrhythmias, Cardiac | ['Bradycardia'] |
741 | 1 | Role of cardiovascular and ionic changes in pathogenesis and prevention of isoprenaline-induced cardiac necrosis. | MEDLINE | Manual | NLM | Blood pressure, heart rate, oxygen uptake, and blood values of PO2, PCO2, and pH were studied in unanesthetized rats for 8 hours. After a cardiotoxic dose of 20 mg/kg isoprenaline, s.c., blood pressure fell from 117 to 72 mm Hg, heart rate accelerated from 326 to 497 beats/minute, and cardiac work diminished by about 1... | Recent advances in studies on cardiac structure and metabolism | 0363-5872 | Print | 6 | null | Print | 1,975 | null | null | 135-42 | O Strubelt (O); C P Siegers (CP) | Journal Article (D016428) | Carbon Dioxide (Registry: 142M471B3J, UI: D002245); Propranolol (Registry: 9Y8NXQ24VQ, UI: D011433); Verapamil (Registry: CJ0O37KU29, UI: D014700); Isoproterenol (Registry: L628TT009W, UI: D007545); Oxygen (Registry: S88TT14065, UI: D010100) | Animals (UI: D000818, Major: No); Blood Pressure (UI: D001794, Major: No) - Qualifiers: drug effects (UI: Q000187, Major: No); Carbon Dioxide (UI: D002245, Major: No) - Qualifiers: blood (UI: Q000097, Major: No); Cardiomyopathies (UI: D009202, Major: No) - Qualifiers: chemically induced (UI: Q000139, Major: Yes); patho... | Animals|Blood Pressure|Carbon Dioxide|Cardiomyopathies|Heart Rate|Hydrogen-Ion Concentration|Isoproterenol|Male|Myocardium|Necrosis|Oxygen|Oxygen Consumption|Propranolol|Rats|Verapamil | |drug effects (0)|blood (0)|chemically induced (1); pathology (0); physiopathology (0); prevention & control (0)|drug effects (0)||antagonists & inhibitors (0); pharmacology (1)||metabolism (0)||blood (0)|drug effects (0)|therapeutic use (0)||therapeutic use (0) | 0|0|0|0|0|0|0|0|0|0|0|0|0|0|0 | null | 1976-02-27 | 2013-11-21 | pubmed: 1975-1-1; medline: 1975-1-1 0:1; entrez: 1975-1-1 0:0 | pubmed: 741 | Cardiomyopathies | [] |
742 | 1 | Alterations in norepinephrine pattern in the damaged myocardium in the rat. | MEDLINE | Manual | NLM | In the albino rat, the evolvement of myocardial necrosis induced by a single injection of ISO was accompanied by a fall in total NE. Pretreatment with propranolol and pargyline protected against ISO-induced necrosis and myocardial hypertrophy, but did not influence the ISO-induced depletion of NE stores. The depletion ... | Recent advances in studies on cardiac structure and metabolism | 0363-5872 | Print | 6 | null | Print | 1,975 | null | null | 159-65 | B Bhagat (B); J M Sullivan (JM); N S Dhalla (NS) | Journal Article (D016428) | Pargyline (Registry: 9MV14S8G3E, UI: D010293); Propranolol (Registry: 9Y8NXQ24VQ, UI: D011433); Tyrosine 3-Monooxygenase (Registry: EC 1.14.16.2, UI: D014446); Monoamine Oxidase (Registry: EC 1.4.3.4, UI: D008995); Isoproterenol (Registry: L628TT009W, UI: D007545); Norepinephrine (Registry: X4W3ENH1CV, UI: D009638) | Animals (UI: D000818, Major: No); Cardiomegaly (UI: D006332, Major: No) - Qualifiers: chemically induced (UI: Q000139, Major: No); Cardiomyopathies (UI: D009202, Major: No) - Qualifiers: chemically induced (UI: Q000139, Major: No); metabolism (UI: Q000378, Major: Yes); pathology (UI: Q000473, Major: No); Isoproterenol ... | Animals|Cardiomegaly|Cardiomyopathies|Isoproterenol|Male|Monoamine Oxidase|Myocardium|Necrosis|Norepinephrine|Pargyline|Propranolol|Rats|Tyrosine 3-Monooxygenase | |chemically induced (0)|chemically induced (0); metabolism (1); pathology (0)|pharmacology (1)||metabolism (0)|enzymology (0); metabolism (0)||metabolism (1)|pharmacology (0)|pharmacology (0)||metabolism (0) | 0|0|0|0|0|0|0|0|0|0|0|0|0 | null | 1976-02-27 | 2013-11-21 | pubmed: 1975-1-1; medline: 1975-1-1 0:1; entrez: 1975-1-1 0:0 | pubmed: 742 | Cardiomyopathies | [] |
743 | 1 | Prevention of myocardial Ca overload and necrotization by Mg and K salts or acidosis. | MEDLINE | Manual | NLM | The crucial point in the pathogenesis of isoproterenol-induced myocardial necrotization is an abundant intracellular Ca accumulation leading to high energy phosphate exhaustion. Accordingly, in the early stage of the isoproterenol-induced necrotization process, the onset of ATP and creatine phosphate breakdown strictly... | Recent advances in studies on cardiac structure and metabolism | 0363-5872 | Print | 6 | null | Print | 1,975 | null | null | 33-42 | J Janke (J); A Fleckenstein (A); B Hein (B); O Leder (O); H Sigel (H) | Journal Article (D016428) | Phosphocreatine (Registry: 020IUV4N33, UI: D010725); Adenosine Triphosphate (Registry: 8L70Q75FXE, UI: D000255); Magnesium (Registry: I38ZP9992A, UI: D008274); Isoproterenol (Registry: L628TT009W, UI: D007545); Potassium (Registry: RWP5GA015D, UI: D011188); Calcium (Registry: SY7Q814VUP, UI: D002118) | Adenosine Triphosphate (UI: D000255, Major: No) - Qualifiers: metabolism (UI: Q000378, Major: No); Animals (UI: D000818, Major: No); Calcium (UI: D002118, Major: No) - Qualifiers: antagonists & inhibitors (UI: Q000037, Major: Yes); metabolism (UI: Q000378, Major: No); Cardiomyopathies (UI: D009202, Major: No) - Qualifi... | Adenosine Triphosphate|Animals|Calcium|Cardiomyopathies|Dose-Response Relationship, Drug|Hydrogen-Ion Concentration|Isoproterenol|Magnesium|Myocardium|Necrosis|Phosphocreatine|Potassium|Rats | metabolism (0)||antagonists & inhibitors (1); metabolism (0)|chemically induced (0); metabolism (0); prevention & control (1)|||antagonists & inhibitors (0)|pharmacology (0); therapeutic use (1)|metabolism (0)||metabolism (0)|pharmacology (0); therapeutic use (1)| | 0|0|0|0|0|0|0|0|0|0|0|0|0 | null | 1976-02-27 | 2017-03-22 | pubmed: 1975-1-1; medline: 1975-1-1 0:1; entrez: 1975-1-1 0:0 | pubmed: 743 | Cardiomyopathies | [] |
1,351 | 1 | Effect of the beta-receptor blocking agent Visken on the action of coumarin. | MEDLINE | Manual | NLM | In a double-blind study, the influence of Visken on the effect of anticoagulant therapy with Marcoumar was examined. In comparison to a placebo group, neither any influence on the Quick time, nor any increased tendency to haemorrhage bleeding could be detected. | International journal of clinical pharmacology and biopharmacy | 0340-0026 | Print | 12 | 4 | Print | 1,975 | Dec | null | 458-60 | H Vinazzer (H) | Clinical Trial (D016430); Controlled Clinical Trial (D018848); Journal Article (D016428) | Adrenergic beta-Antagonists (Registry: 0, UI: D000319); Anticoagulants (Registry: 0, UI: D000925); Coumarins (Registry: 0, UI: D003374); Placebos (Registry: 0, UI: D010919) | Adrenergic beta-Antagonists (UI: D000319, Major: No) - Qualifiers: pharmacology (UI: Q000494, Major: Yes); Age Factors (UI: D000367, Major: No); Aged (UI: D000368, Major: No); Anticoagulants (UI: D000925, Major: No) - Qualifiers: therapeutic use (UI: Q000627, Major: No); Arterial Occlusive Diseases (UI: D001157, Major:... | Adrenergic beta-Antagonists|Age Factors|Aged|Anticoagulants|Arterial Occlusive Diseases|Blood Coagulation|Blood Coagulation Disorders|Body Height|Body Weight|Coronary Disease|Coumarins|Drug Interactions|Drug Therapy, Combination|Humans|Long-Term Care|Male|Middle Aged|Myocardial Infarction|Placebos|Time Factors | pharmacology (1)|||therapeutic use (0)|drug therapy (0)|drug effects (1)|drug therapy (0)|||drug therapy (0)|pharmacology (1)|||||||drug therapy (0)|| | 0|0|0|0|0|0|0|0|0|0|0|0|0|0|0|0|0|0|0|0 | null | 1976-03-24 | 2004-11-17 | pubmed: 1975-12-1; medline: 1975-12-1 0:1; entrez: 1975-12-1 0:0 | pubmed: 1351 | Myocardial Ischemia | ['Coronary Disease', 'Myocardial Infarction'] |
1,448 | 1 | Defects in the biochemistry of collagen in diseases of connective tissue. | MEDLINE | Manual | NLM | The collagens are the major structural glycoproteins of connective tissues. A unique primary structure and a multiplicity of post-translational modification reactions are required for normal fibrillogenesis. The post-translational modifications include hydroxylation of prolyl and lysyl residues, glycosylation, folding ... | The Journal of investigative dermatology | 0022-202X | Print | 66 | 02 | Print | 1,976 | Feb | null | 59-79 | J Uitto (J); J R Lichtenstein (JR) | Journal Article (D016428); Research Support, U.S. Gov't, Non-P.H.S. (D013486); Research Support, U.S. Gov't, P.H.S. (D013487); Review (D016454) | Hydroxylysine (Registry: 2GQB349IUB, UI: D006901); Collagen (Registry: 9007-34-5, UI: D003094); Protein-Lysine 6-Oxidase (Registry: EC 1.4.3.13, UI: D008249); Microbial Collagenase (Registry: EC 3.4.24.3, UI: D003012); Hydroxyproline (Registry: RMB44WO89X, UI: D006909) | Aortic Diseases (UI: D001018, Major: No) - Qualifiers: etiology (UI: Q000209, Major: No); Bone and Bones (UI: D001842, Major: No) - Qualifiers: abnormalities (UI: Q000002, Major: No); Brain Diseases (UI: D001927, Major: No) - Qualifiers: genetics (UI: Q000235, Major: No); Collagen (UI: D003094, Major: No) - Qualifiers:... | Aortic Diseases|Bone and Bones|Brain Diseases|Collagen|Connective Tissue|Cutis Laxa|Ehlers-Danlos Syndrome|Fascia|Genetic Linkage|Homocystinuria|Humans|Hydroxylysine|Hydroxyproline|Joints|Marfan Syndrome|Microbial Collagenase|Osteogenesis Imperfecta|Protein Biosynthesis|Protein Conformation|Protein-Lysine 6-Oxidase|Sex... | etiology (0)|abnormalities (0)|genetics (0)|biosynthesis (1); metabolism (0)|metabolism (1)|metabolism (0); pathology (0)|genetics (0); metabolism (0); pathology (0)|abnormalities (0)||metabolism (0)||biosynthesis (0)|biosynthesis (0); urine (0)|abnormalities (0)|metabolism (0)|metabolism (0)|metabolism (0); pathology ... | 0|0|0|0|0|0|0|0|0|0|0|0|0|0|0|0|0|0|0|0|0|0 | null | 1976-04-01 | 2019-07-23 | pubmed: 1976-2-1; medline: 1976-2-1 0:1; entrez: 1976-2-1 0:0 | pubmed: 1448; pii: S0022-202X(15)44682-2; doi: 10.1111/1523-1747.ep12481404 | Heart Defects, Congenital | ['Marfan Syndrome'] |
1,567 | 1 | [Certain problems of treatment of ischemic heart disease]. | MEDLINE | Manual | NLM | On the basis of extended personal experience and of the literature data, the authors give recommendations for differentiated rational drug therapy of different stages of ischaemic heart disease. The results of a study of comparative efficacy of 15 coronary-active drugs used in 709 patients with ischaemic heart disease ... | Kardiologiia | 0022-9040 | Print | 15 | 7 | Print | 1,975 | Jul | null | 16-24 | I P Zamotaev (IP); L G Lozinskiĭ (LG); M G Venediktova (MG); B L Sandomirskiĭ (BL) | English Abstract (D004740); Journal Article (D016428) | Adrenergic beta-Antagonists (Registry: 0, UI: D000319); Vasodilator Agents (Registry: 0, UI: D014665) | Adrenergic beta-Antagonists (UI: D000319, Major: No) - Qualifiers: pharmacology (UI: Q000494, Major: No); therapeutic use (UI: Q000627, Major: Yes); Angina Pectoris (UI: D000787, Major: No) - Qualifiers: drug therapy (UI: Q000188, Major: No); Coronary Disease (UI: D003327, Major: No) - Qualifiers: drug therapy (UI: Q00... | Adrenergic beta-Antagonists|Angina Pectoris|Coronary Disease|Drug Evaluation|Heart|Humans|Myocardial Contraction|Vasodilator Agents | pharmacology (0); therapeutic use (1)|drug therapy (0)|drug therapy (1); physiopathology (0)||physiopathology (0)||drug effects (0)|pharmacology (0); therapeutic use (0) | 0|0|0|0|0|0|0|0 | null | 1976-04-02 | 2017-03-10 | pubmed: 1975-7-1; medline: 1975-7-1 0:1; entrez: 1975-7-1 0:0 | pubmed: 1567 | Myocardial Ischemia | ['Angina Pectoris', 'Coronary Disease'] |
1,568 | 1 | [Stimulators of beta-adrenergic structures in treatment of ischemic heart disease]. | MEDLINE | Manual | NLM | The beneficial effect of stimulators of beta-adrenergic structures (Myophedrin on the haemodynamics and the inotropic function of the myocardium was demonstrated experimentally (in 12 rabbits) and clinically (in 53 patients with ischaemic heart disease). A positive effect of the treatment was noted in 45.5% of those pa... | Kardiologiia | 0022-9040 | Print | 15 | 7 | Print | 1,975 | Jul | null | 37-43 | F I Komarov (FI); L I Ol'binskaia (LI); A A Abinder (AA); V V Iankin (VV); I T Kitaeva (IT) | English Abstract (D004740); Journal Article (D016428) | Adrenergic beta-Agonists (Registry: 0, UI: D000318) | Adrenergic beta-Agonists (UI: D000318, Major: No) - Qualifiers: pharmacology (UI: Q000494, Major: No); therapeutic use (UI: Q000627, Major: Yes); Adult (UI: D000328, Major: No); Aged (UI: D000368, Major: No); Animals (UI: D000818, Major: No); Coronary Disease (UI: D003327, Major: No) - Qualifiers: drug therapy (UI: Q00... | Adrenergic beta-Agonists|Adult|Aged|Animals|Coronary Disease|Electrocardiography|Female|Heart|Hemodynamics|Humans|Male|Middle Aged|Myocardial Contraction|Rabbits|Stimulation, Chemical | pharmacology (0); therapeutic use (1)||||drug therapy (1); physiopathology (0)|||physiopathology (0)|drug effects (0)||||drug effects (1)|| | 0|0|0|0|0|0|0|0|0|0|0|0|0|0|0 | null | 1976-04-02 | 2017-03-10 | pubmed: 1975-7-1; medline: 1975-7-1 0:1; entrez: 1975-7-1 0:0 | pubmed: 1568 | Myocardial Ischemia | ['Coronary Disease'] |
1,569 | 1 | [Nonachlasine--a new drug for treatment of ischemic heart disease]. | MEDLINE | Manual | NLM | Data on the pharmacology of a new antianginal drug--Nonachlasine--are presented. Nonachlasine was found to increase the blood flow intensively and for long periods of time, increasing the oxygen reserve of the myocardium, thus increasing the cardiac output and the contractile function of the heart. The prevailing actio... | Kardiologiia | 0022-9040 | Print | 15 | 7 | Print | 1,975 | Jul | null | 43-8 | N V Kaverina (NV); G A Markova (GA); G G Chichkanov (GG); V B Chumburidze (VB); A I Basaeva (AI) | English Abstract (D004740); Journal Article (D016428) | Adrenergic beta-Agonists (Registry: 0, UI: D000318); Phenothiazines (Registry: 0, UI: D010640) | Adrenergic beta-Agonists (UI: D000318, Major: No) - Qualifiers: therapeutic use (UI: Q000627, Major: Yes); Animals (UI: D000818, Major: No); Blood Pressure (UI: D001794, Major: No) - Qualifiers: drug effects (UI: Q000187, Major: No); Cardiac Output (UI: D002302, Major: No) - Qualifiers: drug effects (UI: Q000187, Major... | Adrenergic beta-Agonists|Animals|Blood Pressure|Cardiac Output|Cats|Coronary Disease|Drug Evaluation|Hemodynamics|Phenothiazines|Rabbits|Rats|Regional Blood Flow|Vascular Resistance | therapeutic use (1)||drug effects (0)|drug effects (0)||drug therapy (1); physiopathology (0)||drug effects (0)|therapeutic use (1)|||drug effects (0)|drug effects (0) | 0|0|0|0|0|0|0|0|0|0|0|0|0 | null | 1976-04-02 | 2017-03-10 | pubmed: 1975-7-1; medline: 1975-7-1 0:1; entrez: 1975-7-1 0:0 | pubmed: 1569 | Myocardial Ischemia | ['Coronary Disease'] |
1,570 | 1 | [Cordaron and nonachlasine in treatment of chronic coronary insufficiency]. | MEDLINE | Manual | NLM | In a double blind study of the clinical effect of Cordaron conducted in 55 patients with chronic ischaemic heart disease a positive effect was obtained in 80.4% of the cases, an effect of placebo-in 24.3%. Cordaron was especially effective in patients with localized stenoses of the coronary arteries. Nonachlasine (an a... | Kardiologiia | 0022-9040 | Print | 15 | 7 | Print | 1,975 | Jul | null | 48-51 | V I Metelitsa (VI); L S Matveeva (LS); G A Borisova (GA); V P Lupanov (VP) | Clinical Trial (D016430); Controlled Clinical Trial (D018848); English Abstract (D004740); Journal Article (D016428) | Adrenergic beta-Agonists (Registry: 0, UI: D000318); Benzofurans (Registry: 0, UI: D001572); Phenothiazines (Registry: 0, UI: D010640); Amiodarone (Registry: N3RQ532IUT, UI: D000638) | Adrenergic beta-Agonists (UI: D000318, Major: No) - Qualifiers: administration & dosage (UI: Q000008, Major: No); therapeutic use (UI: Q000627, Major: Yes); Amiodarone (UI: D000638, Major: No) - Qualifiers: therapeutic use (UI: Q000627, Major: Yes); Benzofurans (UI: D001572, Major: No) - Qualifiers: therapeutic use (UI... | Adrenergic beta-Agonists|Amiodarone|Benzofurans|Chronic Disease|Clinical Trials as Topic|Coronary Disease|Drug Evaluation|Follow-Up Studies|Humans|Male|Middle Aged|Phenothiazines | administration & dosage (0); therapeutic use (1)|therapeutic use (1)|therapeutic use (1)|||drug therapy (1)||||||therapeutic use (1) | 0|0|0|0|0|0|0|0|0|0|0|0 | null | 1976-04-02 | 2017-03-10 | pubmed: 1975-7-1; medline: 1975-7-1 0:1; entrez: 1975-7-1 0:0 | pubmed: 1570 | Myocardial Ischemia | ['Coronary Disease'] |
1,571 | 1 | [Effect of certain drugs, used in treatment of chronic coronary insufficiency, on adenosine metabolism]. | MEDLINE | Manual | NLM | It has been demonstrated that the study of the activity of 5'-nucleotidase and adenosine-desaminase permits to interpret the metabolism of adenosine. Curanthil, Sustac and Intensain influence the adenosine metabolism favouring an elevation of its content. The therapeutic effect of Obsidan is not conditioned by the ""ad... | Kardiologiia | 0022-9040 | Print | 15 | 7 | Print | 1,975 | Jul | null | 51-6 | E Sh Khalfen (ESh); S G Denisova (SG) | English Abstract (D004740); Journal Article (D016428) | Adrenergic beta-Antagonists (Registry: 0, UI: D000319); Vasodilator Agents (Registry: 0, UI: D014665); Nucleotidases (Registry: EC 3.1.3.-, UI: D009708); Adenosine Deaminase (Registry: EC 3.5.4.4, UI: D000243); Adenosine (Registry: K72T3FS567, UI: D000241) | Adenosine (UI: D000241, Major: No) - Qualifiers: metabolism (UI: Q000378, Major: Yes); Adenosine Deaminase (UI: D000243, Major: No) - Qualifiers: metabolism (UI: Q000378, Major: No); Adrenergic beta-Antagonists (UI: D000319, Major: No) - Qualifiers: therapeutic use (UI: Q000627, Major: Yes); Adult (UI: D000328, Major: ... | Adenosine|Adenosine Deaminase|Adrenergic beta-Antagonists|Adult|Aged|Coronary Disease|Female|Humans|Male|Middle Aged|Myocardium|Nucleotidases|Vasodilator Agents | metabolism (1)|metabolism (0)|therapeutic use (1)|||drug therapy (1); enzymology (0); metabolism (0)|||||enzymology (0)|metabolism (0)|therapeutic use (1) | 0|0|0|0|0|0|0|0|0|0|0|0|0 | null | 1976-04-02 | 2017-03-10 | pubmed: 1975-7-1; medline: 1975-7-1 0:1; entrez: 1975-7-1 0:0 | pubmed: 1571 | Myocardial Ischemia | ['Coronary Disease'] |
1,704 | 1 | Cardiovascular effects of electrical stimulation of the forebrain in the fetal lamb. | MEDLINE | Manual | NLM | Modified stereotaxic techniques were applied to fetal lambs during the latter third of gestation. Electrical stimulation in the region of the hypothalamus in 10 acute experiments was associated with three patterns of arterial blood pressure and heart rate changes: a pressor-tachycardia response; a pure tachycardia resp... | Pediatric research | 0031-3998 | Print | 10 | 1 | Print | 1,976 | Jan | null | 40-5 | R L Williams (RL); R P Hof (RP); M A Heymann (MA); A M Rudolph (AM) | Journal Article (D016428); Research Support, U.S. Gov't, P.H.S. (D013487) | Adrenergic beta-Antagonists (Registry: 0, UI: D000319) | Adrenergic beta-Antagonists (UI: D000319, Major: No) - Qualifiers: pharmacology (UI: Q000494, Major: No); Animals (UI: D000818, Major: No); Blood Pressure (UI: D001794, Major: Yes) - Qualifiers: drug effects (UI: Q000187, Major: No); Bradycardia (UI: D001919, Major: No) - Qualifiers: etiology (UI: Q000209, Major: No); ... | Adrenergic beta-Antagonists|Animals|Blood Pressure|Bradycardia|Electric Stimulation|Heart Rate|Humans|Hypothalamus|Sheep|Stereotaxic Techniques|Tachycardia | pharmacology (0)||drug effects (0)|etiology (0)||drug effects (0)||embryology (0); physiology (1)|||etiology (0) | 0|0|1|0|0|1|0|0|0|0|0 | null | 1976-03-30 | 2006-11-15 | pubmed: 1976-1-1; medline: 1976-1-1 0:1; entrez: 1976-1-1 0:0 | pubmed: 1704; doi: 10.1203/00006450-197601000-00008 | Arrhythmias, Cardiac | ['Bradycardia', 'Tachycardia'] |
1,832 | 1 | Effects of pH and pCO2 on performance of ischemic myocardium. | MEDLINE | Manual | NLM | Contractile performance of ischemic feline myocardium was evaluated under conditions of selective changes in perfusate in pH and pCO2. A substantial increase in myocardial performance was noted when the pCO2 was lowered at constant pH, and depression of performance was noted when the pCO2 was increased at constant pH. ... | Recent advances in studies on cardiac structure and metabolism | 0363-5872 | Print | 10 | null | Print | 1,975 | null | null | 355-64 | M L Weisfeldt (ML); R L Bishop (RL); H L Greene (HL) | Journal Article (D016428); Research Support, U.S. Gov't, P.H.S. (D013487) | Carbon Dioxide (Registry: 142M471B3J, UI: D002245) | Acidosis (UI: D000138, Major: No) - Qualifiers: metabolism (UI: Q000378, Major: No); physiopathology (UI: Q000503, Major: No); Alkalosis (UI: D000471, Major: No) - Qualifiers: metabolism (UI: Q000378, Major: No); physiopathology (UI: Q000503, Major: No); Animals (UI: D000818, Major: No); Carbon Dioxide (UI: D002245, Ma... | Acidosis|Alkalosis|Animals|Carbon Dioxide|Cats|Coronary Disease|Heart|Hydrogen-Ion Concentration|Pressure | metabolism (0); physiopathology (0)|metabolism (0); physiopathology (0)||blood (1)||metabolism (0); physiopathology (1)|physiopathology (1)|| | 0|0|0|0|0|0|0|1|0 | null | 1976-04-01 | 2013-11-21 | pubmed: 1975-1-1; medline: 1975-1-1 0:1; entrez: 1975-1-1 0:0 | pubmed: 1832 | Myocardial Ischemia | ['Coronary Disease'] |
1,849 | 1 | Roentgenological findings in cryptorchidism. | MEDLINE | Manual | NLM | Intravenous urography of 78 cryptorchid boys revealed no clinically significant upper urinary tract anomalies. Two boys had a rotated kidney and 2 others a double renal pelvis. One boy had previously been operated upon because of hydronephrosis. There thus appears to be no reason for routine intravenous urography of cr... | Scandinavian journal of urology and nephrology | 0036-5599 | Print | 9 | 3 | Print | 1,975 | null | null | 171-3 | K J Tveter (KJ); J Fjaerli (J) | Journal Article (D016428) | null | Abnormalities, Multiple (UI: D000015, Major: No); Cryptorchidism (UI: D003456, Major: No) - Qualifiers: complications (UI: Q000150, Major: No); diagnostic imaging (UI: Q000000981, Major: Yes); Heart Defects, Congenital (UI: D006330, Major: No) - Qualifiers: complications (UI: Q000150, Major: No); Humans (UI: D006801, M... | Abnormalities, Multiple|Cryptorchidism|Heart Defects, Congenital|Humans|Kidney|Male|Spinal Dysraphism|Urography | |complications (0); diagnostic imaging (1)|complications (0)||abnormalities (0)||complications (0)| | 0|0|0|0|0|0|0|0 | null | 1976-03-18 | 2019-09-02 | pubmed: 1975-1-1; medline: 1975-1-1 0:1; entrez: 1975-1-1 0:0 | pubmed: 1849; doi: 10.3109/00365597509134205 | Heart Defects, Congenital | [] |
1,865 | 1 | Direct revascularization of acute myocardial infarction by implantation of left internal mammary artery into infarcted left ventricular myocardium. | MEDLINE | Manual | NLM | This is a preliminary report. Clearly, the internal mammary artery implanted into the infarcted anterolateral portion of the wall of the left ventricle has been of help in decreasing the size of the infarction and in maintaining the life of the dogs and normal function six hours after a large left ventricular wall myoc... | Surgery, gynecology & obstetrics | 0039-6087 | Print | 140 | 1 | Print | 1,975 | Jan | null | 44-52 | A Vineberg (A); S Afridi (S); S Sahi (S) | Journal Article (D016428) | null | Acute Disease (UI: D000208, Major: No); Animals (UI: D000818, Major: No); Coronary Artery Bypass (UI: D001026, Major: No) - Qualifiers: methods (UI: Q000379, Major: No); Dogs (UI: D004285, Major: No); Humans (UI: D006801, Major: No); Myocardial Infarction (UI: D009203, Major: No) - Qualifiers: diagnostic imaging (UI: Q... | Acute Disease|Animals|Coronary Artery Bypass|Dogs|Humans|Myocardial Infarction|Myocardial Revascularization|Myocardium|Radiography | ||methods (0)|||diagnostic imaging (0); pathology (0); surgery (1)|methods (0)|pathology (0)| | 0|0|0|0|0|0|1|0|0 | null | 1976-04-01 | 2016-11-23 | pubmed: 1975-1-1; medline: 1975-1-1 0:1; entrez: 1975-1-1 0:0 | pubmed: 1865 | Myocardial Ischemia | ['Myocardial Infarction'] |
1,868 | 1 | Effects of beta-adrenergic stimulating and blocking agents on the adrenaline response and adenyl cyclase activity of leukocyte in monkey and human being. | MEDLINE | Manual | NLM | Using the method in which leukocyte suspensions were incubated with NaF or metaproterenol at 30 degrees C for 15-30 min to allow them to convert 3H-ATP (10 muCi) to 3H-cyclic AMP, followed by separation of the formed 3H-cyclic AMP by common chromatography, the leukocyte adenyl cyclase activity of monkeys and human bein... | The Tohoku journal of experimental medicine | 0040-8727 | Print | 117 | 2 | Print | 1,975 | Oct | null | 125-33 | S Mue (S); T Ise (T); K Akasaka (K); T Takishima (T) | Journal Article (D016428) | Adrenergic beta-Agonists (Registry: 0, UI: D000318); Adrenergic beta-Antagonists (Registry: 0, UI: D000319); Blood Glucose (Registry: 0, UI: D001786); Lactates (Registry: 0, UI: D007773); Metaproterenol (Registry: 53QOG569E0, UI: D009921); Propranolol (Registry: 9Y8NXQ24VQ, UI: D011433); Adenylyl Cyclases (Registry: EC... | Adenylyl Cyclases (UI: D000262, Major: No) - Qualifiers: blood (UI: Q000097, Major: Yes); Adrenergic beta-Agonists (UI: D000318, Major: No) - Qualifiers: pharmacology (UI: Q000494, Major: Yes); Adrenergic beta-Antagonists (UI: D000319, Major: No) - Qualifiers: pharmacology (UI: Q000494, Major: Yes); Aged (UI: D000368, ... | Adenylyl Cyclases|Adrenergic beta-Agonists|Adrenergic beta-Antagonists|Aged|Animals|Blood Glucose|Coronary Disease|Eosinophils|Epinephrine|Female|Haplorhini|Heart Rate|Humans|Lactates|Leukocytes|Male|Metaproterenol|Middle Aged|Propranolol|Time Factors | blood (1)|pharmacology (1)|pharmacology (1)|||metabolism (0)|enzymology (0)|drug effects (0)|blood (0); pharmacology (1)|||drug effects (0)||blood (0)|drug effects (0); enzymology (1)||pharmacology (0)||pharmacology (0)| | 0|0|0|0|0|0|0|0|0|0|0|0|0|0|0|0|0|0|0|0 | null | 1976-03-30 | 2019-07-27 | pubmed: 1975-10-1; medline: 1975-10-1 0:1; entrez: 1975-10-1 0:0 | pubmed: 1868; doi: 10.1620/tjem.117.125 | Myocardial Ischemia | ['Coronary Disease'] |
2,004 | 1 | Electrocardiographic changes and cardiac arrhythmias in patients receiving psychotropic drugs. | MEDLINE | Manual | NLM | Eight patients had cardiac manifestations that were life-threatening in five while taking psychotropic drugs, either phenothiazines or tricyclic antidepressants. Although most patients were receiving several drugs, Mellaril (thioridazine) appeared to be responsible for five cases of ventricular tachycardia, one of whic... | The American journal of cardiology | 0002-9149 | Print | 37 | 2 | Print | 1,976 | Feb | null | 223-30 | N O Fowler (NO); D McCall (D); T C Chou (TC); J C Holmes (JC); I B Hanenson (IB) | Case Reports (D002363); Journal Article (D016428) | Adrenergic Agonists (Registry: 0, UI: D000322); Antidepressive Agents, Tricyclic (Registry: 0, UI: D000929); Digitalis Glycosides (Registry: 0, UI: D004071); Diuretics (Registry: 0, UI: D004232); Phenothiazines (Registry: 0, UI: D010640); Psychotropic Drugs (Registry: 0, UI: D011619); Mesoridazine (Registry: 5XE4NWM740... | Adrenergic Agonists (UI: D000322, Major: No) - Qualifiers: therapeutic use (UI: Q000627, Major: No); Adult (UI: D000328, Major: No); Aged (UI: D000368, Major: No); Antidepressive Agents, Tricyclic (UI: D000929, Major: No) - Qualifiers: pharmacology (UI: Q000494, Major: No); Arrhythmias, Cardiac (UI: D001145, Major: No)... | Adrenergic Agonists|Adult|Aged|Antidepressive Agents, Tricyclic|Arrhythmias, Cardiac|Cardiovascular System|Chlorpromazine|Digitalis Glycosides|Diuretics|Electrocardiography|Female|Heart Failure|Humans|Hypotension|Lidocaine|Male|Mesoridazine|Middle Aged|Phenothiazines|Psychotropic Drugs|Thioridazine | therapeutic use (0)|||pharmacology (0)|chemically induced (1); drug therapy (0)|drug effects (0)|adverse effects (0)|therapeutic use (0)|therapeutic use (0)|||chemically induced (0); drug therapy (0)||chemically induced (0); drug therapy (0)|therapeutic use (0)||adverse effects (0)||pharmacology (0)|adverse effects (1)... | 0|0|0|0|0|0|0|0|0|1|0|0|0|0|0|0|0|0|0|0|0 | null | 1976-04-02 | 2019-06-22 | pubmed: 1976-2-1; medline: 1976-2-1 0:1; entrez: 1976-2-1 0:0 | pubmed: 2004; pii: 0002-9149(76)90316-7; doi: 10.1016/0002-9149(76)90316-7 | Heart Failure | [] |
2,074 | 1 | [Congenital cardiopathies appearing during the neonatal period. The view points of the cardiologist, the hemodynamics specialist, the surgeon, and the anesthetist]. | MEDLINE | Manual | NLM | The best chances of survival for a new-born depend on the following factors: the possibility of clinical and haemodynamic diagnosis of the malformation, adequate reanimation and surgery. All this must be carried out as early as possible. Although catheterization is very risky it should be complete and as fast as possib... | Annales de l'anesthesiologie francaise | 0003-4061 | Print | 16 Spec No 1 | null | Print | 1,975 | null | null | 161-9 | A Fiemeyer (A); F Leca-Chetochine (F); M Thibert (M); Y Louville (Y); J Mathey (J); M Cara (M) | English Abstract (D004740); Journal Article (D016428) | null | Anesthesia, General (UI: D000768, Major: Yes); Aortic Coarctation (UI: D001017, Major: No) - Qualifiers: surgery (UI: Q000601, Major: No); Cardiac Catheterization (UI: D006328, Major: No); Heart Defects, Congenital (UI: D006330, Major: No) - Qualifiers: surgery (UI: Q000601, Major: Yes); Humans (UI: D006801, Major: No)... | Anesthesia, General|Aortic Coarctation|Cardiac Catheterization|Heart Defects, Congenital|Humans|Infant, Newborn|Preoperative Care|Tetralogy of Fallot|Transposition of Great Vessels | |surgery (0)||surgery (1)||||surgery (0)|surgery (0) | 1|0|0|0|0|0|0|0|0 | null | 1976-03-30 | 2017-03-22 | pubmed: 1975-1-1; medline: 1975-1-1 0:1; entrez: 1975-1-1 0:0 | pubmed: 2074 | Heart Defects, Congenital | ['Aortic Coarctation', 'Tetralogy of Fallot', 'Transposition of Great Vessels'] |
2,092 | 1 | Effects of the cardioselective beta-blocker metoprolol in angina pectoris. A subacute study with exercise tests. | MEDLINE | Manual | NLM | The effects of the cardioselective beta-blocker, metoprolol, were evaluated under double-blind conditions in eighteen patients with angina pectoris. During an introductory run-in period of eight weeks, a placebo was given single-blindly. Thereafter two double-blind crossover periods each of four weeks followed, either ... | Annals of clinical research | 0003-4762 | Print | 7 | 6 | Print | 1,975 | Dec | null | 433-41 | O Keyriläinen (O); A Uustialo (A) | Clinical Trial (D016430); Controlled Clinical Trial (D018848); Journal Article (D016428); Randomized Controlled Trial (D016449) | Adrenergic beta-Antagonists (Registry: 0, UI: D000319); Propanolamines (Registry: 0, UI: D011412) | Adrenergic beta-Antagonists (UI: D000319, Major: No) - Qualifiers: adverse effects (UI: Q000009, Major: No); therapeutic use (UI: Q000627, Major: Yes); Adult (UI: D000328, Major: No); Aged (UI: D000368, Major: No); Angina Pectoris (UI: D000787, Major: No) - Qualifiers: drug therapy (UI: Q000188, Major: Yes); Blood Pres... | Adrenergic beta-Antagonists|Adult|Aged|Angina Pectoris|Blood Pressure|Cardiac Output|Clinical Trials as Topic|Drug Evaluation|Exercise Test|Female|Heart Rate|Humans|In Vitro Techniques|Male|Middle Aged|Propanolamines|Time Factors | adverse effects (0); therapeutic use (1)|||drug therapy (1)|drug effects (0)|drug effects (0)|||||drug effects (0)|||||adverse effects (0); therapeutic use (1)| | 0|0|0|0|0|0|0|0|0|0|0|0|0|0|0|0|0 | null | 1976-04-02 | 2014-11-20 | pubmed: 1975-12-1; medline: 1975-12-1 0:1; entrez: 1975-12-1 0:0 | pubmed: 2092 | Myocardial Ischemia | ['Angina Pectoris'] |
2,481 | 1 | Cardiovascular and beta-adrenergic blocking effects of timolol. | MEDLINE | Manual | NLM | The haemodynamic effects of timolol and its inhibiting action on the cardiovascular and bronchial effects of isoproterenol have been studied. Splanchnic nerve activity was recorded. The antiarrhythmic action of timolol was studied on guinea pig isolated atria, using arrhythmias induced by epinephrine, ouabain or corona... | European journal of pharmacology | 0014-2999 | Print | 35 | 2 | Print | 1,976 | Feb | null | 235-43 | P Mouillé (P); H Schmitt (H); G Cheymol (G); E Gauter (E) | Journal Article (D016428) | Adrenergic beta-Antagonists (Registry: 0, UI: D000319); Propanolamines (Registry: 0, UI: D011412); Thiadiazoles (Registry: 0, UI: D013830); Propranolol (Registry: 9Y8NXQ24VQ, UI: D011433); Isoproterenol (Registry: L628TT009W, UI: D007545) | Adrenergic beta-Antagonists (UI: D000319, Major: Yes); Airway Resistance (UI: D000403, Major: No) - Qualifiers: drug effects (UI: Q000187, Major: No); Animals (UI: D000818, Major: No); Aorta (UI: D001011, Major: No) - Qualifiers: drug effects (UI: Q000187, Major: No); Arrhythmias, Cardiac (UI: D001145, Major: No) - Qua... | Adrenergic beta-Antagonists|Airway Resistance|Animals|Aorta|Arrhythmias, Cardiac|Blood Pressure|Bronchi|Coronary Circulation|Dogs|Female|Guinea Pigs|Heart Atria|Heart Rate|Hemodynamics|In Vitro Techniques|Isoproterenol|Male|Myocardial Contraction|Propanolamines|Propranolol|Splanchnic Nerves|Thiadiazoles|Time Factors | |drug effects (0)||drug effects (0)|chemically induced (0); physiopathology (0)|drug effects (0)|drug effects (0)|drug effects (0)||||drug effects (0)|drug effects (0)|drug effects (1)||antagonists & inhibitors (0)||drug effects (0)|pharmacology (1)|pharmacology (0)|physiology (0)|pharmacology (1)| | 1|0|0|0|0|0|0|0|0|0|0|0|0|0|0|0|0|0|0|0|0|0|0 | null | 1976-04-19 | 2019-06-23 | pubmed: 1976-2-1; medline: 1976-2-1 0:1; entrez: 1976-2-1 0:0 | pubmed: 2481; pii: 0014-2999(76)90225-9; doi: 10.1016/0014-2999(76)90225-9 | Arrhythmias, Cardiac | [] |
2,527 | 1 | [Inflammatory cerebro-vascular disease: angiographic findings and distribution patterns (author's transl)]. | MEDLINE | Manual | NLM | Although cerebral angiography should be approached with caution in the diagnosis of inflammatory cerebro-vascular disease there are some characteristic angiographic findings which may be helpful for classification and differential diagnosis. The proximal cerebral arteries are favourably affected by basal meningitis and... | Fortschritte der Neurologie, Psychiatrie, und ihrer Grenzgebiete | 0015-8194 | Print | 43 | 12 | Print | 1,975 | Dec | null | 631-47 | P Stoeter (P); E Ortega-Suhrkamp (E); K Voigt (K) | Journal Article (D016428) | null | Adult (UI: D000328, Major: No); Arteritis (UI: D001167, Major: No) - Qualifiers: diagnostic imaging (UI: Q000000981, Major: No); Cerebral Angiography (UI: D002533, Major: No); Cerebrovascular Disorders (UI: D002561, Major: No) - Qualifiers: complications (UI: Q000150, Major: No); diagnostic imaging (UI: Q000000981, Maj... | Adult|Arteritis|Cerebral Angiography|Cerebrovascular Disorders|Diagnosis, Differential|Female|Giant Cell Arteritis|Humans|Malaria|Male|Meningitis|Middle Aged|Mycoses|Polyarteritis Nodosa|Syphilis, Cardiovascular|Thromboangiitis Obliterans|Tuberculosis, Cardiovascular | |diagnostic imaging (0)||complications (0); diagnostic imaging (1)|||diagnostic imaging (0)||diagnostic imaging (0)||complications (0)||diagnostic imaging (0)|diagnostic imaging (0)|diagnostic imaging (0)|complications (0)|diagnostic imaging (0) | 0|0|0|0|0|0|0|0|0|0|0|0|0|0|0|0|0 | null | 1976-04-19 | 2016-11-23 | pubmed: 1975-12-1; medline: 1975-12-1 0:1; entrez: 1975-12-1 0:0 | pubmed: 2527 | Cerebrovascular Disorders | ['Cerebrovascular Disorders'] |
2,820 | 1 | Surgical management of severe aortic coarctation and interrupted aortic arch in neonates. | MEDLINE | Manual | NLM | Forty-four infants, 2 to 90 days of age, with severe obstructive lesions of the aortic arch, underwent emergency surgical correction between Jan. 1, 1966, and April 1, 1975. The typical clinical presentation was severe congestive heart failure and acidemia. Resection of an aortic coarctation with end-to-end anastomosis... | The Journal of thoracic and cardiovascular surgery | 0022-5223 | Print | 71 | 1 | Print | 1,976 | Jan | null | 35-48 | N H Fishman (NH); M H Bronstein (MH); W Berman (W); B B Roe (BB); L H Edmunds (LH); S J Robinson (SJ); A M Rudolph (AM) | Journal Article (D016428) | null | Aorta (UI: D001011, Major: No) - Qualifiers: abnormalities (UI: Q000002, Major: Yes); Aortic Coarctation (UI: D001017, Major: No) - Qualifiers: complications (UI: Q000150, Major: No); mortality (UI: Q000401, Major: No); surgery (UI: Q000601, Major: Yes); Heart Defects, Congenital (UI: D006330, Major: No) - Qualifiers: ... | Aorta|Aortic Coarctation|Heart Defects, Congenital|Heart Failure|Humans|Hydrogen-Ion Concentration|Infant|Infant, Newborn | abnormalities (1)|complications (0); mortality (0); surgery (1)|complications (0); mortality (0); surgery (1)|etiology (0)|||| | 0|0|0|0|0|0|0|0 | null | 1976-04-15 | 2007-11-15 | pubmed: 1976-1-1; medline: 2001-3-28 10:1; entrez: 1976-1-1 0:0 | pubmed: 2820 | Heart Failure | [] |
2,821 | 1 | Pharmacological analysis of the adrenergic control of the cerebral circulation. | MEDLINE | Manual | NLM | The adrenergic control of the cerebral circulation was subjected to pharmacological analysis. The status of the cerebral circulation was assessed using radioisotope, electromagnetic and resistographic methods. EEG, ECG and arterial pressure were recorded. The acid-base equilibrium and oxygen tension were measured in th... | Medical biology | 0302-2137 | Print | 53 | 6 | Print | 1,975 | Dec | null | 493-500 | R S Mirzoyan (RS) | Journal Article (D016428) | Phenoxybenzamine (Registry: 0TTZ664R7Z, UI: D010643); Dihydroergotoxine (Registry: 11032-41-0, UI: D004088); Potassium Chloride (Registry: 660YQ98I10, UI: D011189); Propranolol (Registry: 9Y8NXQ24VQ, UI: D011433); Nialamide (Registry: T2Q0RYM725, UI: D009526); Norepinephrine (Registry: X4W3ENH1CV, UI: D009638); Guaneth... | Acid-Base Equilibrium (UI: D000136, Major: No) - Qualifiers: drug effects (UI: Q000187, Major: No); Animals (UI: D000818, Major: No); Blood Pressure (UI: D001794, Major: No) - Qualifiers: drug effects (UI: Q000187, Major: No); Cats (UI: D002415, Major: No); Cerebrovascular Circulation (UI: D002560, Major: Yes) - Qualif... | Acid-Base Equilibrium|Animals|Blood Pressure|Cats|Cerebrovascular Circulation|Cerebrovascular Disorders|Dihydroergotoxine|Dogs|Electric Stimulation|Guanethidine|Hydrogen-Ion Concentration|Nialamide|Norepinephrine|Partial Pressure|Phenoxybenzamine|Potassium Chloride|Propranolol|Vasomotor System | drug effects (0)||drug effects (0)||drug effects (0)|physiopathology (0)|pharmacology (0)|||pharmacology (0)||pharmacology (0)|pharmacology (0)||pharmacology (0)|pharmacology (0)|pharmacology (0)|drug effects (0) | 0|0|0|0|1|0|0|0|0|0|0|0|0|0|0|0|0|1 | null | 1976-04-09 | 2013-11-21 | pubmed: 1975-12-1; medline: 1975-12-1 0:1; entrez: 1975-12-1 0:0 | pubmed: 2821 | Cerebrovascular Disorders | ['Cerebrovascular Disorders'] |
2,928 | 1 | Canine cardiac lymph potassium, pH and flow after experimental myocardial infarction. | MEDLINE | Manual | NLM | Canine cardiac lymph was studied after acute experimental myocardial infarction. The lymph potassium concentration remained the same, the lymph potassium content increased, the lymph pH decreased, and the lymph flow increased while the serum potassium and pH remained the same. It is suggested that localized hypoxia may... | Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) | 0037-9727 | Print | 151 | 1 | Print | 1,976 | Jan | null | 146-8 | H N Uhley (HN); S E Leeds (SE); F R Elevitch (FR) | Journal Article (D016428); Research Support, U.S. Gov't, P.H.S. (D013487) | Potassium (Registry: RWP5GA015D, UI: D011188) | Animals (UI: D000818, Major: No); Dogs (UI: D004285, Major: No); Endocardium (UI: D004699, Major: No); Hydrogen-Ion Concentration (UI: D006863, Major: Yes); Lymph Nodes (UI: D008198, Major: No) - Qualifiers: metabolism (UI: Q000378, Major: Yes); physiology (UI: Q000502, Major: No); Myocardial Infarction (UI: D009203, M... | Animals|Dogs|Endocardium|Hydrogen-Ion Concentration|Lymph Nodes|Myocardial Infarction|Potassium | ||||metabolism (1); physiology (0)|metabolism (1)|blood (0); metabolism (1) | 0|0|0|1|0|0|0 | null | 1976-04-09 | 2020-09-30 | pubmed: 1976-1-1; medline: 1976-1-1 0:1; entrez: 1976-1-1 0:0 | pubmed: 2928; doi: 10.3181/00379727-151-39162 | Myocardial Ischemia | ['Myocardial Infarction'] |
2,973 | 1 | [Prinzmetal angina: clinical aspects and coronarographic findings]. | MEDLINE | Manual | NLM | The clinical course and coronary arteriographic findings in 5 patients with Prinzmetal's variant angina pectoris are reviewed. In 4 patients who had ST-elevations inferiorly, 1 had minimal, 1 only slight, and 1 medium coronary artery disease; 1 had coronary spasm. 1 patient with ST-elevation anteriorly had severe steno... | Schweizerische medizinische Wochenschrift | 0036-7672 | Print | 106 | 5 | Print | 1,976 | Jan | 31 | 141-6 | I Renggli (I); F Burkart (F) | English Abstract (D004740); Journal Article (D016428) | Adrenergic beta-Antagonists (Registry: 0, UI: D000319); Nitroglycerin (Registry: G59M7S0WS3, UI: D005996) | Adrenergic beta-Antagonists (UI: D000319, Major: No) - Qualifiers: therapeutic use (UI: Q000627, Major: No); Adult (UI: D000328, Major: No); Angina Pectoris (UI: D000787, Major: No) - Qualifiers: diagnosis (UI: Q000175, Major: Yes); drug therapy (UI: Q000188, Major: No); surgery (UI: Q000601, Major: No); Arterial Occlu... | Adrenergic beta-Antagonists|Adult|Angina Pectoris|Arterial Occlusive Diseases|Coronary Angiography|Coronary Artery Bypass|Female|Humans|Male|Middle Aged|Nitroglycerin | therapeutic use (0)||diagnosis (1); drug therapy (0); surgery (0)|diagnosis (0)|||||||therapeutic use (0) | 0|0|0|0|1|0|0|0|0|0|0 | null | 1976-04-27 | 2013-11-21 | pubmed: 1976-1-31; medline: 1976-1-31 0:1; entrez: 1976-1-31 0:0 | pubmed: 2973 | Myocardial Ischemia | ['Angina Pectoris'] |
3,026 | 1 | [The correlation between activity of enzymes participating in the formation and utilization of acetyl CoA in rabbit heart mitochondria in myocarditis and normal state]. | MEDLINE | Manual | NLM | Activities in rabbit heart mitochondria of acetoacetyl-CoA-thyolase, pyruvate dehydrogenase, acetyl CoA-synthetase, citrate synthase and acetyl carnitine transferase were compared. These enzymes participate in formation and utilization of acetyl-CoA. The acetoacetyl-CoA-thyolase and acetyl CoA-synthetase were shown to ... | Voprosy meditsinskoi khimii | 0042-8809 | Print | 21 | 6 | Print | null | null | null | 625-9 | E V Sharkova (EV) | English Abstract (D004740); Journal Article (D016428) | Pyruvate Dehydrogenase Complex (Registry: 0, UI: D011768); Acetyl Coenzyme A (Registry: 72-89-9, UI: D000105); Acetyltransferases (Registry: EC 2.3.1.-, UI: D000123); Acetyl-CoA C-Acetyltransferase (Registry: EC 2.3.1.9, UI: D000101); Citrate (si)-Synthase (Registry: EC 2.3.3.1, UI: D002950); Coenzyme A (Registry: SAA0... | Acetyl Coenzyme A (UI: D000105, Major: No) - Qualifiers: metabolism (UI: Q000378, Major: Yes); Acetyl-CoA C-Acetyltransferase (UI: D000101, Major: No) - Qualifiers: metabolism (UI: Q000378, Major: No); Acetyltransferases (UI: D000123, Major: No) - Qualifiers: metabolism (UI: Q000378, Major: No); Animals (UI: D000818, M... | Acetyl Coenzyme A|Acetyl-CoA C-Acetyltransferase|Acetyltransferases|Animals|Citrate (si)-Synthase|Coenzyme A|Mitochondria, Muscle|Myocarditis|Myocardium|Pyruvate Dehydrogenase Complex|Rabbits | metabolism (1)|metabolism (0)|metabolism (0)||metabolism (0)|analogs & derivatives (1)|metabolism (1)|metabolism (1)|metabolism (1)|metabolism (0)| | 0|0|0|0|0|0|0|0|0|0|0 | null | 1976-04-23 | 2013-11-21 | pubmed: 1975-11-1; medline: 1975-11-1 0:1; entrez: 1975-11-1 0:0 | pubmed: 3026 | Cardiomyopathies | ['Myocarditis'] |
3,073 | 1 | [Findings of subpartal monitoring, status of the newborn infant and evaluation of cardiotocographic findings]. | MEDLINE | Manual | NLM | The parameters of the intrapartal fetal CTG and the actual pH are related to each other and to the Apgar score of the newborn. The interpretation was carried out by means of groups of 300 to 600 cases. The actual fetal pH has the most compact relation to the Apgar score of the newborn (C equals 0,31). But also this con... | Zentralblatt fur Gynakologie | 0044-4197 | Print | 98 | 1 | Print | 1,976 | null | null | 3-9 | V Bollmann (V); E P Issel (EP); H Halle (H); D Ballauf (D); C Füssel (C) | English Abstract (D004740); Journal Article (D016428) | null | Acidosis (UI: D000138, Major: No) - Qualifiers: diagnosis (UI: Q000175, Major: No); Apgar Score (UI: D001034, Major: No); Bradycardia (UI: D001919, Major: No) - Qualifiers: diagnosis (UI: Q000175, Major: No); Female (UI: D005260, Major: No); Fetal Blood (UI: D005312, Major: No); Fetal Diseases (UI: D005315, Major: No) ... | Acidosis|Apgar Score|Bradycardia|Female|Fetal Blood|Fetal Diseases|Fetal Heart|Heart Rate|Humans|Hydrogen-Ion Concentration|Infant, Newborn|Obstetric Labor Complications|Pregnancy|Prenatal Diagnosis|Tachycardia|Uterine Contraction | diagnosis (0)||diagnosis (0)|||diagnosis (1)|physiopathology (0)|||||diagnosis (0)|||diagnosis (0)| | 0|0|0|0|0|0|0|0|0|0|1|0|0|0|0|0 | null | 1976-04-27 | 2008-02-11 | pubmed: 1976-1-1; medline: 1976-1-1 0:1; entrez: 1976-1-1 0:0 | pubmed: 3073 | Arrhythmias, Cardiac | ['Bradycardia', 'Tachycardia'] |
3,096 | 1 | Factors of importance for the degree of ischemic injury in the isolated rat heart. | MEDLINE | Manual | NLM | Isolated working rat hearts were made ischemic by introducing a one-way aortic ball valve. After the ischemic period the hearts were perfused in a retrograde non-working way for 30 min. Flow rates, glycogen, ATP, and creatine-phosphate went down during the time of ischemia, whereas tissue lactate accumulated. For short... | Acta medica Scandinavica. Supplementum | 0365-463X | Print | 587 | null | Print | 1,976 | null | null | 141-9 | A P Waldenstrõm (AP); A C Hjalmarson (AC) | Journal Article (D016428) | Lactates (Registry: 0, UI: D007773); Phosphocreatine (Registry: 020IUV4N33, UI: D010725); Adenosine Triphosphate (Registry: 8L70Q75FXE, UI: D000255); Glycogen (Registry: 9005-79-2, UI: D006003) | Adenosine Triphosphate (UI: D000255, Major: No) - Qualifiers: metabolism (UI: Q000378, Major: No); Animals (UI: D000818, Major: No); Coronary Circulation (UI: D003326, Major: No); Coronary Disease (UI: D003327, Major: Yes) - Qualifiers: metabolism (UI: Q000378, Major: No); physiopathology (UI: Q000503, Major: No); Glyc... | Adenosine Triphosphate|Animals|Coronary Circulation|Coronary Disease|Glycogen|Heart|Heart Rate|Hydrogen-Ion Concentration|Lactates|Male|Perfusion|Phosphocreatine|Rats | metabolism (0)|||metabolism (0); physiopathology (0)|metabolism (0)|physiopathology (0)|||metabolism (0)|||metabolism (0)| | 0|0|0|1|0|0|0|0|0|0|0|0|0 | null | 1976-04-30 | 2019-09-11 | pubmed: 1976-1-1; medline: 1976-1-1 0:1; entrez: 1976-1-1 0:0 | pubmed: 3096; doi: 10.1111/j.0954-6820.1976.tb05876.x | Myocardial Ischemia | ['Coronary Disease'] |
3,095 | 1 | Effects of metabolic and pharmacologic interventions on myocardial infarct size following coronary occlusion. | MEDLINE | Manual | NLM | A number of hemodynamic, pharmacologic and metabolic interventions were found to change the extent of acute ischemic injury of the myocardium and subsequent necrosis following experimental coronary artery occlusion. Reduction in myocardial damage occurred by decreasing myocardial oxygen demands (beta-adrenergic blockin... | Acta medica Scandinavica. Supplementum | 0365-463X | Print | 587 | null | Print | 1,976 | null | null | 125-36 | P R Maroko (PR); E Braunwald (E) | Journal Article (D016428); Research Support, U.S. Gov't, P.H.S. (D013487) | Adrenergic alpha-Agonists (Registry: 0, UI: D000316); Adrenergic beta-Antagonists (Registry: 0, UI: D000319); Isoproterenol (Registry: L628TT009W, UI: D007545) | Acute Disease (UI: D000208, Major: No); Adrenergic alpha-Agonists (UI: D000316, Major: No) - Qualifiers: pharmacology (UI: Q000494, Major: No); therapeutic use (UI: Q000627, Major: No); Adrenergic beta-Antagonists (UI: D000319, Major: No) - Qualifiers: pharmacology (UI: Q000494, Major: No); therapeutic use (UI: Q000627... | Acute Disease|Adrenergic alpha-Agonists|Adrenergic beta-Antagonists|Animals|Assisted Circulation|Dogs|Hemodynamics|Humans|Isoproterenol|Myocardial Infarction|Myocardium|Necrosis|Oxygen Consumption | |pharmacology (0); therapeutic use (0)|pharmacology (0); therapeutic use (0)||||drug effects (0)||pharmacology (0); therapeutic use (0)|drug therapy (0); metabolism (0); physiopathology (0)|metabolism (1); pathology (0)||drug effects (0) | 0|0|0|0|0|0|0|0|0|1|0|0|0 | null | 1976-04-30 | 2019-09-11 | pubmed: 1976-1-1; medline: 1976-1-1 0:1; entrez: 1976-1-1 0:0 | pubmed: 3095; doi: 10.1111/j.0954-6820.1976.tb05874.x | Myocardial Ischemia | ['Myocardial Infarction'] |
3,098 | 1 | Double-blind study of the effect of cardioselective beta-blockade on chest pain in acute myocardial infarction. | MEDLINE | Manual | NLM | A double-blind study including three different cardioselective beta-blockers, practolol, H 87/07 and metoprolol, was performed in 54 patients with acute myocardial infarction and chest pain shortly after onset of symptoms. Transmural infarctions were found in 42 patients while 12 patients had nontransmural infarctions.... | Acta medica Scandinavica. Supplementum | 0365-463X | Print | 587 | null | Print | 1,976 | null | null | 201-8 | F Waagstein (F); A C Hjalmarson (AC) | Clinical Trial (D016430); Journal Article (D016428); Randomized Controlled Trial (D016449) | Adrenergic beta-Antagonists (Registry: 0, UI: D000319); Propanolamines (Registry: 0, UI: D011412); Practolol (Registry: SUG9176GRW, UI: D011217) | Acute Disease (UI: D000208, Major: No); Adrenergic beta-Antagonists (UI: D000319, Major: No) - Qualifiers: pharmacology (UI: Q000494, Major: No); therapeutic use (UI: Q000627, Major: Yes); Blood Pressure (UI: D001794, Major: No) - Qualifiers: drug effects (UI: Q000187, Major: No); Clinical Trials as Topic (UI: D002986,... | Acute Disease|Adrenergic beta-Antagonists|Blood Pressure|Clinical Trials as Topic|Heart Rate|Humans|Middle Aged|Myocardial Contraction|Myocardial Infarction|Pain|Practolol|Propanolamines | |pharmacology (0); therapeutic use (1)|drug effects (0)||drug effects (0)|||drug effects (0)|drug therapy (1)||pharmacology (0); therapeutic use (0)|pharmacology (0); therapeutic use (1) | 0|0|0|0|0|0|0|0|0|0|0|0 | null | 1976-04-30 | 2019-09-11 | pubmed: 1976-1-1; medline: 1976-1-1 0:1; entrez: 1976-1-1 0:0 | pubmed: 3098; doi: 10.1111/j.0954-6820.1976.tb05882.x | Myocardial Ischemia | ['Myocardial Infarction'] |
3,150 | 1 | Kawasaki disease. Relationship with infantile periarteritis nodosa. | MEDLINE | Manual | NLM | Until 1972, Kawasaki disease, or acute febrile infantile mucocutaneous lymph node syndrome (MCLS), was considered in Japan to be a nonfatal disease with a favorable prognosis. Based on the findings from two autopsy cases of MCLS, we believe that sudden and unexpected death during convalescence may be due to arterial le... | Archives of pathology & laboratory medicine | 0003-9985 | Print | 100 | 2 | Print | 1,976 | Feb | null | 81-6 | N Tanaka (N); K Sekimoto (K); S Naoe (S) | Journal Article (D016428) | null | Age Factors (UI: D000367, Major: No); Child (UI: D002648, Major: No); Child, Preschool (UI: D002675, Major: No); Coronary Vessels (UI: D003331, Major: No) - Qualifiers: pathology (UI: Q000473, Major: No); Edema, Cardiac (UI: D004489, Major: No) - Qualifiers: pathology (UI: Q000473, Major: No); Erythema (UI: D004890, Ma... | Age Factors|Child|Child, Preschool|Coronary Vessels|Edema, Cardiac|Erythema|Female|Heart Aneurysm|Humans|Infant|Japan|Lymphatic Diseases|Male|Polyarteritis Nodosa|Renal Artery|Syndrome|Thymus Gland | |||pathology (0)|pathology (0)|mortality (0); pathology (0)||pathology (0)||||mortality (0); pathology (1)||mortality (0); pathology (1)|pathology (0)||pathology (0) | 0|0|0|0|0|0|0|0|0|0|0|0|0|0|0|0|0 | null | 1976-04-30 | 2004-11-17 | pubmed: 1976-2-1; medline: 1976-2-1 0:1; entrez: 1976-2-1 0:0 | pubmed: 3150 | Cardiomyopathies | ['Edema, Cardiac'] |
3,241 | 1 | [Role of P50 in resuscitation (author's transl)]. | MEDLINE | Manual | NLM | The amount of oxygen made available to the tissues of the body depends essentially upon pulmonary gas exchanges, cardiac output and its regional distribution, haemoglobin concentration and also upon the oxygen affinity of the haemoglobin molecule. That a standard oxyhaemoglobin dissociation curve faithfully describes o... | Bulletin de physio-pathologie respiratoire | 0007-439X | Print | 11 | 5 | Print | null | null | null | 637-58 | P Foëx (P) | Journal Article (D016428); Review (D016454) | Carbon Dioxide (Registry: 142M471B3J, UI: D002245) | Blood (UI: D001769, Major: No); Carbon Dioxide (UI: D002245, Major: No) - Qualifiers: physiology (UI: Q000502, Major: No); Cardiac Output (UI: D002302, Major: No); Cardiovascular Diseases (UI: D002318, Major: No) - Qualifiers: physiopathology (UI: Q000503, Major: No); Coronary Disease (UI: D003327, Major: No) - Qualifi... | Blood|Carbon Dioxide|Cardiac Output|Cardiovascular Diseases|Coronary Disease|Diabetes Mellitus|Extracorporeal Circulation|Humans|Hydrogen-Ion Concentration|Hypoxia|Kidney Failure, Chronic|Respiratory Tract Diseases|Resuscitation|Shock | |physiology (0)||physiopathology (0)|physiopathology (0)|physiopathology (0)||||physiopathology (0)|physiopathology (0)|physiopathology (0)||physiopathology (0) | 0|0|0|0|0|0|0|0|0|0|0|0|1|0 | null | 1976-05-18 | 2016-11-23 | pubmed: 1975-9-1; medline: 1975-9-1 0:1; entrez: 1975-9-1 0:0 | pubmed: 3241 | Myocardial Ischemia | ['Coronary Disease'] |
3,242 | 1 | [Isotopic study of fluid and electrolyte disturbances in decompensated chronic respiratory insufficiency (author's transl)]. | MEDLINE | Manual | NLM | The study of fluid and electrolyte disturbances by isotope radiodilution method is carried out in 22 patients with chronic respiratory insufficiency and cardiac failure. The simultaneous measurements of hydro-ionic compartments have been carried out with tritiated water (HTO), labelled sodium (22Na), labelled potassium... | Bulletin de physio-pathologie respiratoire | 0007-439X | Print | 11 | 5 | Print | null | null | null | 683-707 | F Wattel (F); J Lefèvre (J); C Chopin (C); D Lottin (D); B Raviart (B) | English Abstract (D004740); Journal Article (D016428) | Carbon Dioxide (Registry: 142M471B3J, UI: D002245); Chlorine (Registry: 4R7X1O2820, UI: D002713); Sodium (Registry: 9NEZ333N27, UI: D012964); Potassium (Registry: RWP5GA015D, UI: D011188); Oxygen (Registry: S88TT14065, UI: D010100) | Aged (UI: D000368, Major: No); Blood (UI: D001769, Major: No); Body Water (UI: D001834, Major: No) - Qualifiers: metabolism (UI: Q000378, Major: No); Carbon Dioxide (UI: D002245, Major: No) - Qualifiers: blood (UI: Q000097, Major: No); Chlorine (UI: D002713, Major: No) - Qualifiers: metabolism (UI: Q000378, Major: No);... | Aged|Blood|Body Water|Carbon Dioxide|Chlorine|Coronary Disease|Extracellular Space|Humans|Hydrogen-Ion Concentration|Middle Aged|Obesity|Oxygen|Potassium|Respiratory Insufficiency|Sodium|Water-Electrolyte Imbalance | ||metabolism (0)|blood (0)|metabolism (0)|metabolism (0)|metabolism (0)||||complications (0)|blood (0)|metabolism (0)|complications (1)|metabolism (0)|etiology (1) | 0|0|0|0|0|0|0|0|0|0|0|0|0|0|0|0 | null | 1976-05-18 | 2013-11-21 | pubmed: 1975-9-1; medline: 1975-9-1 0:1; entrez: 1975-9-1 0:0 | pubmed: 3242 | Myocardial Ischemia | ['Coronary Disease'] |
3,293 | 1 | Contribution of tissue acidosis to ischemic injury in the perfused rat heart. | MEDLINE | Manual | NLM | The isolated perfused working rat heart preparation has been used to study the effects of respiratory acidosis on myocardial metabolism and contractilly. Hearts were perfused with 5 mM glucose and 10(-2) U/ml of insulin in order to enhance metabolsim of glucose relative to that of fatty acids. After perfusion with Kreb... | Circulation | 0009-7322 | Print | 53 | 3 Suppl | Print | 1,976 | Mar | null | I3-14 | J R Williamson (JR); S W Schaffer (SW); C Ford (C); B Safer (B) | Journal Article (D016428); Research Support, U.S. Gov't, P.H.S. (D013487) | Adenine Nucleotides (Registry: 0, UI: D000227); Fatty Acids (Registry: 0, UI: D005227); Fructosephosphates (Registry: 0, UI: D005636); Glucosephosphates (Registry: 0, UI: D005958); Lactates (Registry: 0, UI: D007773); Pyruvates (Registry: 0, UI: D011773); Phosphocreatine (Registry: 020IUV4N33, UI: D010725); NAD (Regist... | Acidosis, Respiratory (UI: D000142, Major: No) - Qualifiers: metabolism (UI: Q000378, Major: Yes); physiopathology (UI: Q000503, Major: No); Adenine Nucleotides (UI: D000227, Major: No) - Qualifiers: metabolism (UI: Q000378, Major: No); Adenosine Monophosphate (UI: D000249, Major: No) - Qualifiers: metabolism (UI: Q000... | Acidosis, Respiratory|Adenine Nucleotides|Adenosine Monophosphate|Animals|Coronary Circulation|Coronary Disease|Cytosol|Fatty Acids|Fructosephosphates|Glucose|Glucosephosphates|Heart Ventricles|Hydrogen-Ion Concentration|In Vitro Techniques|Lactates|Male|Myocardium|NAD|NADP|Oxygen Consumption|Phosphocreatine|Pressure|P... | metabolism (1); physiopathology (0)|metabolism (0)|metabolism (0)|||metabolism (1); physiopathology (0)|metabolism (0)|metabolism (0)|metabolism (0)|metabolism (0)|metabolism (0)|physiopathology (0)|||metabolism (0)||metabolism (1)|metabolism (0)|metabolism (0)||metabolism (0)||metabolism (0)| | 0|0|0|0|0|0|0|0|0|0|0|0|0|0|0|0|0|0|0|0|0|0|0|0 | null | 1976-05-25 | 2014-11-20 | pubmed: 1976-3-1; medline: 1976-3-1 0:1; entrez: 1976-3-1 0:0 | pubmed: 3293 | Myocardial Ischemia | ['Coronary Disease'] |
3,420 | 1 | Anti-arrhythmic action of nadolol, a beta-adrenergic receptor blocking agent. | MEDLINE | Manual | NLM | The anti-arrhythmic action of 2,3-cis-1,2,3,4-tetrahydro-5-[(2-hydroxy-3-tert-butylamino)propoxy]2,3-naphthalenediol (nadolol) was evaluated and compared with that of propranolol in several experimental models of cardiac arrhythmias. Both nadolol and propranolol antagonized isoproterenol-induced tachycardia and ouabain... | European journal of pharmacology | 0014-2999 | Print | 35 | 1 | Print | 1,976 | Jan | null | 17-27 | D B Evans (DB); M T Peschka (MT); R J Lee (RJ); R J Laffan (RJ) | Journal Article (D016428) | Adrenergic beta-Antagonists (Registry: 0, UI: D000319); Anti-Arrhythmia Agents (Registry: 0, UI: D000889); Naphthols (Registry: 0, UI: D009284); Propanolamines (Registry: 0, UI: D011412); Ouabain (Registry: 5ACL011P69, UI: D010042); Isoproterenol (Registry: L628TT009W, UI: D007545) | Adrenergic beta-Antagonists (UI: D000319, Major: No) - Qualifiers: pharmacology (UI: Q000494, Major: Yes); Animals (UI: D000818, Major: No); Anti-Arrhythmia Agents (UI: D000889, Major: No) - Qualifiers: pharmacology (UI: Q000494, Major: Yes); Arrhythmias, Cardiac (UI: D001145, Major: No) - Qualifiers: chemically induce... | Adrenergic beta-Antagonists|Animals|Anti-Arrhythmia Agents|Arrhythmias, Cardiac|Dogs|Electric Stimulation|Heart|Heart Conduction System|Isoproterenol|Male|Naphthols|Neural Conduction|Ouabain|Propanolamines|Vagus Nerve|Ventricular Fibrillation | pharmacology (1)||pharmacology (1)|chemically induced (0)|||physiopathology (0)|drug effects (0)|antagonists & inhibitors (0)||pharmacology (0)|drug effects (0)|antagonists & inhibitors (0)|pharmacology (1)|physiology (0)|physiopathology (0) | 0|0|0|0|0|0|0|0|0|0|0|0|0|0|0|0 | null | 1976-06-02 | 2019-06-23 | pubmed: 1976-1-1; medline: 1976-1-1 0:1; entrez: 1976-1-1 0:0 | pubmed: 3420; pii: 0014-2999(76)90296-X; doi: 10.1016/0014-2999(76)90296-x | Arrhythmias, Cardiac | ['Ventricular Fibrillation'] |
3,643 | 1 | The antiarrhythmic and cardiovascular properties of 1-dimethyl isopropylamino-3-(2-phenylphenoxy)-propan-2-ol chloride, UM-424. | MEDLINE | Manual | NLM | The quarternary ammonium compound, UM-424 [1-dimethyl isopropylamino-3-(2-phenylphenoxy)-propan-2-ol chloride], was evaluated for its antiarrhythmic and hemodynamic effects. UM-424 converted ouabain-induced ventricular tachycardia in the anesthetized dog when administered in an average dose of 4.6 mg/kg i.v. Pretreatme... | The Journal of pharmacology and experimental therapeutics | 0022-3565 | Print | 196 | 2 | Print | 1,976 | Feb | null | 420-32 | F J Kniffen (FJ); S Winokur (S); R E Counsell (RE); B R Lucchesi (BR) | Journal Article (D016428) | Adrenergic beta-Antagonists (Registry: 0, UI: D000319); Anti-Arrhythmia Agents (Registry: 0, UI: D000889); Propanolamines (Registry: 0, UI: D011412); Quaternary Ammonium Compounds (Registry: 0, UI: D000644); UM-424 (Registry: 58520-98-2, UI: C011588); Ouabain (Registry: 5ACL011P69, UI: D010042); Isoproterenol (Registry... | Adrenergic beta-Antagonists (UI: D000319, Major: No); Animals (UI: D000818, Major: No); Anti-Arrhythmia Agents (UI: D000889, Major: Yes); Arrhythmias, Cardiac (UI: D001145, Major: No) - Qualifiers: chemically induced (UI: Q000139, Major: No); physiopathology (UI: Q000503, Major: No); Blood Pressure (UI: D001794, Major:... | Adrenergic beta-Antagonists|Animals|Anti-Arrhythmia Agents|Arrhythmias, Cardiac|Blood Pressure|Cardiac Output|Cats|Coronary Vessels|Dogs|Drug Interactions|Heart Rate|Hemodynamics|Isoproterenol|Ligation|Male|Myocardial Contraction|Ouabain|Papillary Muscles|Propanolamines|Quaternary Ammonium Compounds|Ventricular Fibrill... | |||chemically induced (0); physiopathology (0)|drug effects (0)|drug effects (0)||physiology (0)|||drug effects (0)|drug effects (1)|pharmacology (0)|||drug effects (0)|pharmacology (0)|drug effects (0)|pharmacology (1)|pharmacology (1)|physiopathology (0) | 0|0|1|0|0|0|0|0|0|0|0|0|0|0|0|0|0|0|0|0|0 | null | 1976-05-10 | 2019-12-10 | pubmed: 1976-2-1; medline: 1976-2-1 0:1; entrez: 1976-2-1 0:0 | pubmed: 3643 | Arrhythmias, Cardiac | ['Ventricular Fibrillation'] |
3,647 | 1 | A new series of cardioselective adrenergic beta-receptor blocking compounds. 1-(2-Acyl-4-acylaminophenoxy)-3-isopropylaminopropan-2-ols. | MEDLINE | Manual | NLM | A series of 1-(2-acyl-4-acylaminophenoxy)-3-isopropylaminopropan-2-ols has been synthesized and examined for beta-receptor blocking and antiarrhythmic activity. Several of these compounds are more than 20 times as active in blocking cardiac beta-receptors than vascular beta-receptors when given intravenously to anesthe... | Journal of medicinal chemistry | 0022-2623 | Print | 19 | 3 | Print | 1,976 | Mar | null | 399-402 | B Basil (B); J R Clark (JR); E C Coffee (EC); R Jordon (R); A H Loveless (AH); D L Pain (DL); K R Wooldridge (KR) | Journal Article (D016428) | Adrenergic beta-Antagonists (Registry: 0, UI: D000319); Anilides (Registry: 0, UI: D000813); Propanolamines (Registry: 0, UI: D011412); Receptors, Adrenergic (Registry: 0, UI: D011941); Ouabain (Registry: 5ACL011P69, UI: D010042); Isoproterenol (Registry: L628TT009W, UI: D007545) | Adrenergic beta-Antagonists (UI: D000319, Major: No) - Qualifiers: chemical synthesis (UI: Q000138, Major: Yes); pharmacology (UI: Q000494, Major: No); Anilides (UI: D000813, Major: No) - Qualifiers: chemical synthesis (UI: Q000138, Major: No); pharmacology (UI: Q000494, Major: No); Animals (UI: D000818, Major: No); Ar... | Adrenergic beta-Antagonists|Anilides|Animals|Arrhythmias, Cardiac|Cats|Dogs|Heart Rate|Isoproterenol|Molecular Conformation|Organ Specificity|Ouabain|Propanolamines|Receptors, Adrenergic|Structure-Activity Relationship | chemical synthesis (1); pharmacology (0)|chemical synthesis (0); pharmacology (0)||chemically induced (0)|||drug effects (0)|antagonists & inhibitors (0)|||antagonists & inhibitors (0)|chemical synthesis (1); pharmacology (0)|drug effects (0)| | 0|0|0|0|0|0|0|0|0|0|0|0|0|0 | null | 1976-05-25 | 2019-07-09 | pubmed: 1976-3-1; medline: 1976-3-1 0:1; entrez: 1976-3-1 0:0 | pubmed: 3647; doi: 10.1021/jm00225a012 | Arrhythmias, Cardiac | [] |
3,889 | 1 | [Extracardiac factors in the development of arrhythmias (author's transl)]. | MEDLINE | Manual | NLM | A brief survey is given of some of the most frequent extracardiac causes which may provoke disturbances of rhythm. The importance of psychogenic and metabolic factors is emphasized. Additional organic lesions cannot be excluded in every case. | Wiener klinische Wochenschrift | 0043-5325 | Print | 87 | 22 | Print | null | null | null | 737-40 | H Mösslacher (H); J Slany (J) | English Abstract (D004740); Journal Article (D016428) | Adrenergic beta-Antagonists (Registry: 0, UI: D000319); Hypnotics and Sedatives (Registry: 0, UI: D006993); Sympathomimetics (Registry: 0, UI: D013566); Atropine (Registry: 7C0697DR9I, UI: D001285) | Adrenergic beta-Antagonists (UI: D000319, Major: No) - Qualifiers: therapeutic use (UI: Q000627, Major: No); Arrhythmias, Cardiac (UI: D001145, Major: No) - Qualifiers: chemically induced (UI: Q000139, Major: No); drug therapy (UI: Q000188, Major: No); etiology (UI: Q000209, Major: Yes); Atropine (UI: D001285, Major: N... | Adrenergic beta-Antagonists|Arrhythmias, Cardiac|Atropine|Central Nervous System Diseases|Humans|Hyperthyroidism|Hypnotics and Sedatives|Neurotic Disorders|Psychotherapy|Reflex|Sympathomimetics|Water-Electrolyte Imbalance | therapeutic use (0)|chemically induced (0); drug therapy (0); etiology (1)|therapeutic use (0)|complications (0)||complications (0)|therapeutic use (0)|complications (0)|||therapeutic use (0)|complications (0) | 0|0|0|0|0|0|0|0|0|0|0|0 | null | 1976-06-02 | 2013-11-21 | pubmed: 1975-11-1; medline: 1975-11-1 0:1; entrez: 1975-11-1 0:0 | pubmed: 3889 | Arrhythmias, Cardiac | [] |
3,949 | 1 | Pattern of enzyme activity following acute myocardial infarction with special reference to gamma-glutamyl transpeptidase. | MEDLINE | Manual | NLM | The present study on 55 consecutive patients with acute myocardial infarction (AMI) draws attention to the relationship between different enzyme maxima in AMI, with special reference to serum gamma-glutamyl transpeptidase (S-GT). In more than 60% of the patients the S-GT was increased during the hospital stay. The S-GT... | Acta medica Scandinavica | 0001-6101 | Print | 199 | 3 | Print | 1,976 | null | null | 217-21 | U Säwe (U); L R Erhardt (LR); A Sjögren (A) | Journal Article (D016428) | L-Lactate Dehydrogenase (Registry: EC 1.1.1.27, UI: D007770); gamma-Glutamyltransferase (Registry: EC 2.3.2.2, UI: D005723); Alanine Transaminase (Registry: EC 2.6.1.2, UI: D000410); Creatine Kinase (Registry: EC 2.7.3.2, UI: D003402); Alkaline Phosphatase (Registry: EC 3.1.3.1, UI: D000469) | Acute Disease (UI: D000208, Major: No); Alanine Transaminase (UI: D000410, Major: No) - Qualifiers: blood (UI: Q000097, Major: No); Alkaline Phosphatase (UI: D000469, Major: No) - Qualifiers: blood (UI: Q000097, Major: No); Creatine Kinase (UI: D003402, Major: No) - Qualifiers: blood (UI: Q000097, Major: No); Female (U... | Acute Disease|Alanine Transaminase|Alkaline Phosphatase|Creatine Kinase|Female|Humans|L-Lactate Dehydrogenase|Liver|Male|Myocardial Infarction|Time Factors|gamma-Glutamyltransferase | |blood (0)|blood (0)|blood (0)|||blood (0)|physiopathology (0)||enzymology (1); physiopathology (0)||blood (1) | 0|0|0|0|0|0|0|0|0|0|0|0 | null | 1976-05-25 | 2019-08-12 | pubmed: 1976-1-1; medline: 1976-1-1 0:1; entrez: 1976-1-1 0:0 | pubmed: 3949; doi: 10.1111/j.0954-6820.1976.tb06719.x | Myocardial Ischemia | ['Myocardial Infarction'] |
3,959 | 1 | Myocardial ischemia and cell acidosis: Modification by alkali and the effects on ventricular function and cation composition. | MEDLINE | Manual | NLM | Myocardial cell pH was measured with 5, 5 dimethyl-2, 4-oxazolidinedione (DMO) in intact anesthetized dogs by a transient indicator dilution technique. Bolus injections of labeled DMO, vascular, extracellular and water indicators were made into the left anterior descending coronary artery, and blood samples were collec... | The American journal of cardiology | 0002-9149 | Print | 37 | 4 | Print | 1,976 | Mar | 31 | 501-7 | T J Regan (TJ); R M Effros (RM); B Haider (B); H A Oldewurtel (HA); P O Ettinger (PO); S S Ahmed (SS) | Journal Article (D016428); Research Support, U.S. Gov't, P.H.S. (D013487) | Alkalies (Registry: 0, UI: D000468); Carbonates (Registry: 0, UI: D002254); Cations, Monovalent (Registry: 0, UI: D002414); Edetic Acid (Registry: 9G34HU7RV0, UI: D004492); Dimethadione (Registry: ALU9NPM703, UI: D004114) | Acidosis (UI: D000138, Major: No) - Qualifiers: metabolism (UI: Q000378, Major: Yes); Alkalies (UI: D000468, Major: No) - Qualifiers: pharmacology (UI: Q000494, Major: Yes); therapeutic use (UI: Q000627, Major: No); Animals (UI: D000818, Major: No); Body Water (UI: D001834, Major: No) - Qualifiers: metabolism (UI: Q000... | Acidosis|Alkalies|Animals|Body Water|Carbonates|Cations, Monovalent|Coronary Disease|Coronary Vessels|Dimethadione|Dogs|Edetic Acid|Extracellular Space|Heart|Hydrogen-Ion Concentration|Indicator Dilution Techniques|Myocardium | metabolism (1)|pharmacology (1); therapeutic use (0)||metabolism (0)|pharmacology (0)||drug therapy (0); metabolism (0); physiopathology (0)|drug effects (0)|||pharmacology (0)|metabolism (0)|physiopathology (1)|||metabolism (0); pathology (0) | 0|0|0|0|0|0|0|0|0|0|0|0|0|0|0|0 | null | 1976-06-02 | 2019-06-22 | pubmed: 1976-3-31; medline: 1976-3-31 0:1; entrez: 1976-3-31 0:0 | pubmed: 3959; pii: 0002-9149(76)90388-X; doi: 10.1016/0002-9149(76)90388-x | Myocardial Ischemia | ['Coronary Disease'] |
3,960 | 1 | Effects of allopurinol, propranolol and methylprednisolone on infarct size in experimental myocardial infarction. | MEDLINE | Manual | NLM | With use of a canine model of occlusion of the left anterior descending coronary artery and an intracellular lactic dehydrogenase stain to measure infarct size directly, the effects of allopurinol, methylprednisolone sodium succinate and propranolol were studied. Allopurinol did not influence the extent of myocardial n... | The American journal of cardiology | 0002-9149 | Print | 37 | 4 | Print | 1,976 | Mar | 31 | 572-80 | C H Shatney (CH); D J MacCarter (DJ); R C Lillehei (RC) | Journal Article (D016428) | Allopurinol (Registry: 63CZ7GJN5I, UI: D000493); Propranolol (Registry: 9Y8NXQ24VQ, UI: D011433); Oxygen (Registry: S88TT14065, UI: D010100); Methylprednisolone (Registry: X4W7ZR7023, UI: D008775) | Allopurinol (UI: D000493, Major: No) - Qualifiers: pharmacology (UI: Q000494, Major: Yes); therapeutic use (UI: Q000627, Major: No); Animals (UI: D000818, Major: No); Blood (UI: D001769, Major: No); Coronary Disease (UI: D003327, Major: No) - Qualifiers: drug therapy (UI: Q000188, Major: No); Disease Models, Animal (UI... | Allopurinol|Animals|Blood|Coronary Disease|Disease Models, Animal|Dogs|Heart|Hemodynamics|Hydrogen-Ion Concentration|Methylprednisolone|Myocardial Infarction|Myocardium|Oxygen|Propranolol | pharmacology (1); therapeutic use (0)|||drug therapy (0)|||drug effects (0)|drug effects (0)||pharmacology (1); therapeutic use (0)|pathology (1)|metabolism (0)|blood (0)|pharmacology (1); therapeutic use (0) | 0|0|0|0|1|0|0|0|0|0|0|0|0|0 | null | 1976-06-02 | 2019-06-22 | pubmed: 1976-3-31; medline: 1976-3-31 0:1; entrez: 1976-3-31 0:0 | pubmed: 3960; pii: 0002-9149(76)90398-2; doi: 10.1016/0002-9149(76)90398-2 | Myocardial Ischemia | ['Coronary Disease', 'Myocardial Infarction'] |
4,080 | 1 | Effects of the cardioselective beta-adrenergic receptor blocking agent metoprolol in angina pectoris. Subacute study with exercise tests. | MEDLINE | Manual | NLM | The effect of a cardioselective beta-adrenergic blocking agent, metoprolol, on symptoms and exercise tolerance was studied in 16 patients with angina pectoris. Metroprolol was compared with placebo at two dose levels (20 mg t.d.s. and 50 mg t.d.s.) in a double-blind trial in 14 patients. Compared with placebo, metropro... | British heart journal | 0007-0769 | Print | 38 | 2 | Print | 1,976 | Feb | null | 155-61 | L G Ekelund (LG); A G Olsson (AG); L Orö (L); S Rössner (S) | Clinical Trial (D016430); Comparative Study (D003160); Controlled Clinical Trial (D018848); Journal Article (D016428) | Adrenergic beta-Antagonists (Registry: 0, UI: D000319); Propanolamines (Registry: 0, UI: D011412); Nitroglycerin (Registry: G59M7S0WS3, UI: D005996) | Adrenergic beta-Antagonists (UI: D000319, Major: No) - Qualifiers: pharmacology (UI: Q000494, Major: No); therapeutic use (UI: Q000627, Major: Yes); Aged (UI: D000368, Major: No); Angina Pectoris (UI: D000787, Major: No) - Qualifiers: drug therapy (UI: Q000188, Major: Yes); physiopathology (UI: Q000503, Major: No); Blo... | Adrenergic beta-Antagonists|Aged|Angina Pectoris|Blood Pressure|Clinical Trials as Topic|Drug Administration Schedule|Exercise Test|Female|Heart|Heart Rate|Humans|Male|Middle Aged|Nitroglycerin|Propanolamines | pharmacology (0); therapeutic use (1)||drug therapy (1); physiopathology (0)|drug effects (0)|||||physiopathology (0)|drug effects (0)||||administration & dosage (0)|therapeutic use (1) | 0|0|0|0|0|0|0|0|0|0|0|0|0|0|0 | null | 1976-07-06 | 2019-05-03 | pubmed: 1976-2-1; medline: 1976-2-1 0:1; entrez: 1976-2-1 0:0 | pubmed: 4080; pmc: PMC482986; doi: 10.1136/hrt.38.2.155 | Myocardial Ischemia | ['Angina Pectoris'] |
4,084 | 1 | The use of a single venous blood sample to assess oxygen binding in haemoglobin. | MEDLINE | Manual | NLM | The measurement of pH, PO2, PCO2 and SO2 in a single venous blood sample can be used to determine the P50 at standard or at in vivo conditions. This technique makes it feasible for a physician, firstly, to make an assessment of the net adaptation of the red cell to reductions in blood oxygen content or flow and, second... | British journal of haematology | 0007-1048 | Print | 32 | 1 | Print | 1,976 | Jan | null | 89-98 | M A Lichtman (MA); M Murphy (M); M Pogal (M) | Journal Article (D016428); Research Support, U.S. Gov't, Non-P.H.S. (D013486); Research Support, U.S. Gov't, P.H.S. (D013487) | Hemoglobins (Registry: 0, UI: D006454); Oxygen (Registry: S88TT14065, UI: D010100) | Acidosis (UI: D000138, Major: No) - Qualifiers: blood (UI: Q000097, Major: No); Alkalosis (UI: D000471, Major: No) - Qualifiers: blood (UI: Q000097, Major: No); Anemia (UI: D000740, Major: No) - Qualifiers: blood (UI: Q000097, Major: No); Anemia, Sickle Cell (UI: D000755, Major: No) - Qualifiers: blood (UI: Q000097, Ma... | Acidosis|Alkalosis|Anemia|Anemia, Sickle Cell|Blood Specimen Collection|Body Temperature|Coronary Disease|Female|Fetal Blood|Heart Failure|Hemoglobins|Humans|Hydrogen-Ion Concentration|Male|Methods|Oxygen|Veins | blood (0)|blood (0)|blood (0)|blood (0)|||blood (0)|||blood (0)|metabolism (1)|||||blood (1)| | 0|0|0|0|1|0|0|0|0|0|0|0|0|0|0|0|0 | null | 1976-07-06 | 2019-07-04 | pubmed: 1976-1-1; medline: 1976-1-1 0:1; entrez: 1976-1-1 0:0 | pubmed: 4084; doi: 10.1111/j.1365-2141.1976.tb01878.x | Myocardial Ischemia | ['Coronary Disease'] |
4,177 | 1 | [Case of congenital megaurethra associated with bilateral renal hyperplasia]. | MEDLINE | Manual | NLM | Authors report a very rare malformation of the external genital organs in a male new-born who died 48 hours after birth. This malformation consisted in a total aplasia of the corpus cavernosum and bulbus penis with a fusiforme dilatation of the anterior urethra. The malformation was associated with an anal imperforatio... | Bulletin de l'Association des anatomistes | 0376-6160 | Print | 59 | 166 | Print | 1,975 | Sep | null | 591-600 | M Colas (M); B Lauras (B); A Morin (A); J Cuilleret (J) | Case Reports (D002363); English Abstract (D004740); Journal Article (D016428) | null | Abnormalities, Multiple (UI: D000015, Major: Yes); Anus, Imperforate (UI: D001006, Major: No) - Qualifiers: complications (UI: Q000150, Major: No); Cryptorchidism (UI: D003456, Major: No) - Qualifiers: complications (UI: Q000150, Major: No); Heart Defects, Congenital (UI: D006330, Major: No) - Qualifiers: complications... | Abnormalities, Multiple|Anus, Imperforate|Cryptorchidism|Heart Defects, Congenital|Humans|Infant, Newborn|Infant, Premature|Infant, Premature, Diseases|Kidney|Male|Penis|Urethra | |complications (0)|complications (0)|complications (0)|||||abnormalities (1)||abnormalities (0)|abnormalities (1) | 1|0|0|0|0|0|0|1|0|0|0|0 | null | 1976-07-06 | 2006-11-15 | pubmed: 1975-9-1; medline: 1975-9-1 0:1; entrez: 1975-9-1 0:0 | pubmed: 4177 | Heart Defects, Congenital | [] |
4,256 | 1 | Acebultolol: basis for the prediction of effect on exercise tolerance. | MEDLINE | Manual | NLM | Twelve unselected males suffering from documented coronary insufficiency and moderately severe angina submitted to graded multistage treadmill exercise testing on 3 separate days, 3.5 hr after a single dose of 0,200, or 400 mg of acebulolol, a cardioselective beta blocker. Control measures included random allocation of... | Clinical pharmacology and therapeutics | 0009-9236 | Print | 19 | 3 | Print | 1,976 | Mar | null | 333-8 | P Biron (P); G Tremblay (G) | Clinical Trial (D016430); Journal Article (D016428); Randomized Controlled Trial (D016449) | Adrenergic beta-Antagonists (Registry: 0, UI: D000319); Acebutolol (Registry: 67P356D8GH, UI: D000070) | Acebutolol (UI: D000070, Major: No) - Qualifiers: pharmacology (UI: Q000494, Major: Yes); Adrenergic beta-Antagonists (UI: D000319, Major: No) - Qualifiers: pharmacology (UI: Q000494, Major: No); Adult (UI: D000328, Major: No); Angina Pectoris (UI: D000787, Major: No) - Qualifiers: physiopathology (UI: Q000503, Major: ... | Acebutolol|Adrenergic beta-Antagonists|Adult|Angina Pectoris|Blood Pressure|Coronary Disease|Exercise Test|Heart Rate|Humans|Middle Aged|Oxygen Consumption|Physical Exertion|Time Factors | pharmacology (1)|pharmacology (0)||physiopathology (0)|drug effects (0)|physiopathology (1)||drug effects (0)|||drug effects (0)|| | 0|0|0|0|0|0|1|0|0|0|0|0|0 | null | 1976-07-06 | 2019-05-09 | pubmed: 1976-3-1; medline: 1976-3-1 0:1; entrez: 1976-3-1 0:0 | pubmed: 4256; doi: 10.1002/cpt1976193333 | Myocardial Ischemia | ['Angina Pectoris', 'Coronary Disease'] |
4,288 | 1 | The difficult hypertensive. | MEDLINE | Manual | NLM | With the wide range of medications available today it should be possible to obtain satisfactory control in the majority of hypertensive patients. However, there are various categories of patients who may present particular problems in management, as for example patients with cerebro-vascular and coronary disease, or wi... | Drugs | 0012-6667 | Print | 11 | 1 | Print | 1,976 | null | null | 55-60 | J Raftos (J) | Journal Article (D016428); Review (D016454) | Adrenergic beta-Antagonists (Registry: 0, UI: D000319); Antihypertensive Agents (Registry: 0, UI: D000959); Diuretics (Registry: 0, UI: D004232); Vasodilator Agents (Registry: 0, UI: D014665) | Adrenergic beta-Antagonists (UI: D000319, Major: No) - Qualifiers: therapeutic use (UI: Q000627, Major: No); Alcoholism (UI: D000437, Major: No) - Qualifiers: complications (UI: Q000150, Major: No); Antihypertensive Agents (UI: D000959, Major: No) - Qualifiers: therapeutic use (UI: Q000627, Major: No); Cerebrovascular ... | Adrenergic beta-Antagonists|Alcoholism|Antihypertensive Agents|Cerebrovascular Disorders|Coronary Disease|Depression|Diuretics|Drug Resistance|Drug Therapy, Combination|Emotions|Humans|Hypertension|Stress, Physiological|Substance-Related Disorders|Vasodilator Agents | therapeutic use (0)|complications (0)|therapeutic use (0)|complications (0)|complications (0)|complications (0)|therapeutic use (0)|||||complications (0); diagnosis (0); drug therapy (0); therapy (1)|complications (0)|complications (0)|therapeutic use (0) | 0|0|0|0|0|0|0|0|0|0|0|0|0|0|0 | null | 1976-07-06 | 2018-10-25 | pubmed: 1976-1-1; medline: 1976-1-1 0:1; entrez: 1976-1-1 0:0 | pubmed: 4288; doi: 10.2165/00003495-197611010-00005 | Cerebrovascular Disorders | ['Cerebrovascular Disorders'] |
4,649 | 1 | Morphologic and biochemical changes in autolysing dog heart muscle. | MEDLINE | Manual | NLM | The progressive changes in pH, lactate content, and light and electron microscopic appearances were studied in dog myocardium undergoing a 6-hour period of autolysis in vitro at 37 degrees C. and at room temperature. At 37 degrees C. there was a rapid cumulative fall in pH during the 1st hour after excision of the hear... | Laboratory investigation; a journal of technical methods and pathology | 0023-6837 | Print | 34 | 4 | Print | 1,976 | Apr | null | 357-62 | L C Armiger (LC); R N Seelye (RN); V M Carnell (VM); C U Smith (CU); J B Gavin (JB); P B Herdson (PB) | Journal Article (D016428) | Lactates (Registry: 0, UI: D007773); Glycogen (Registry: 9005-79-2, UI: D006003) | Animals (UI: D000818, Major: No); Autolysis (UI: D001329, Major: Yes); Dogs (UI: D004285, Major: No); Glycogen (UI: D006003, Major: No) - Qualifiers: analysis (UI: Q000032, Major: No); Hydrogen-Ion Concentration (UI: D006863, Major: No); Lactates (UI: D007773, Major: No) - Qualifiers: analysis (UI: Q000032, Major: No);... | Animals|Autolysis|Dogs|Glycogen|Hydrogen-Ion Concentration|Lactates|Mitochondria|Myocardial Infarction|Myocardium|Myofibrils | |||analysis (0)||analysis (0)|ultrastructure (0)|pathology (0)|analysis (0); pathology (1); ultrastructure (0)|ultrastructure (0) | 0|1|0|0|0|0|0|0|0|0 | null | 1976-07-06 | 2003-11-14 | pubmed: 1976-4-1; medline: 1976-4-1 0:1; entrez: 1976-4-1 0:0 | pubmed: 4649 | Myocardial Ischemia | ['Myocardial Infarction'] |
4,779 | 1 | Atherosclerotic cerebral infarction: pathophysiologic aspects. | MEDLINE | Manual | NLM | When the supply of substrate to the brain is threatened, homeostatic mechanisms induce cerebral vasodilatation to compensate for the insufficiency. When a region of the brain is rendered completely ischemic, local infarction occurs. The size of the infarct depends partly on the availability of collateral circulation an... | Postgraduate medicine | 0032-5481 | Print | 59 | 3 | Print | 1,976 | Mar | null | 115-8 | J J Caronna (JJ); F H McDowell (FH) | Journal Article (D016428) | null | Blood Flow Velocity (UI: D001783, Major: No); Brain (UI: D001921, Major: No) - Qualifiers: metabolism (UI: Q000378, Major: Yes); Brain Edema (UI: D001929, Major: No) - Qualifiers: etiology (UI: Q000209, Major: No); therapy (UI: Q000628, Major: No); Cerebrovascular Circulation (UI: D002560, Major: Yes); Cerebrovascular ... | Blood Flow Velocity|Brain|Brain Edema|Cerebrovascular Circulation|Cerebrovascular Disorders|Energy Metabolism|Humans|Hydrogen-Ion Concentration|Hypertension|Oxygen Consumption|Regional Blood Flow|Time Factors | |metabolism (1)|etiology (0); therapy (0)||physiopathology (1); prevention & control (0); therapy (0)||||complications (0)||| | 0|0|0|1|0|0|0|0|0|0|0|0 | null | 1976-07-06 | 2019-07-13 | pubmed: 1976-3-1; medline: 1976-3-1 0:1; entrez: 1976-3-1 0:0 | pubmed: 4779; doi: 10.1080/00325481.1976.11714300 | Cerebrovascular Disorders | ['Cerebrovascular Disorders'] |
4,782 | 1 | Myocardial ischemia from coronary arterial spasm. | MEDLINE | Manual | NLM | Spasm of coronary arteries can cause chest pain indistinguishable from classic angina pectoris in patients without atherosclerosis of these vessels or recognizable heart disease. Associated electrocardiographic changes usually correspond to the coronary artery affected and disappear when the attack of pain ends. Sublin... | Postgraduate medicine | 0032-5481 | Print | 59 | 4 | Print | 1,976 | Apr | null | 207-11 | S J Gulotta (SJ); K Geller (K) | Journal Article (D016428) | Adrenergic beta-Antagonists (Registry: 0, UI: D000319) | Adrenergic beta-Antagonists (UI: D000319, Major: No) - Qualifiers: therapeutic use (UI: Q000627, Major: No); Angina Pectoris (UI: D000787, Major: No) - Qualifiers: diagnosis (UI: Q000175, Major: No); drug therapy (UI: Q000188, Major: No); etiology (UI: Q000209, Major: Yes); Coronary Vessels (UI: D003331, Major: Yes); E... | Adrenergic beta-Antagonists|Angina Pectoris|Coronary Vessels|Electrocardiography|Female|Humans|Male|Middle Aged|Myocardial Infarction|Spasm | therapeutic use (0)|diagnosis (0); drug therapy (0); etiology (1)|||||||etiology (0)|complications (1); diagnosis (0); drug therapy (0) | 0|0|1|0|0|0|0|0|0|0 | null | 1976-07-06 | 2019-07-13 | pubmed: 1976-4-1; medline: 1976-4-1 0:1; entrez: 1976-4-1 0:0 | pubmed: 4782; doi: 10.1080/00325481.1976.11714341 | Myocardial Ischemia | ['Angina Pectoris', 'Myocardial Infarction'] |
4,783 | 1 | Angina pectoris. Diagnosis and treatment. | MEDLINE | Manual | NLM | The physician who understands the pathophysiology of angina pectoris can apply rational therapeutic measures based on an appreciation of the determinants of myocardial oxygen supply and demand. Most patients with angina secondary to coronary atherosclerosis can be treated conservatively using a systematic approach that... | Postgraduate medicine | 0032-5481 | Print | 59 | 5 | Print | 1,976 | May | null | 179-88 | R Zelis (R); J A Liedtke (JA); D M Leaman (DM); J D Babb (JD); B H Roberts (BH) | Journal Article (D016428) | Adrenergic beta-Antagonists (Registry: 0, UI: D000319); Digitalis Glycosides (Registry: 0, UI: D004071); Ethanol (Registry: 3K9958V90M, UI: D000431); Nitroglycerin (Registry: G59M7S0WS3, UI: D005996) | Adrenergic beta-Antagonists (UI: D000319, Major: No) - Qualifiers: therapeutic use (UI: Q000627, Major: No); Angina Pectoris (UI: D000787, Major: No) - Qualifiers: diagnosis (UI: Q000175, Major: No); etiology (UI: Q000209, Major: No); therapy (UI: Q000628, Major: Yes); Coronary Disease (UI: D003327, Major: No) - Qualif... | Adrenergic beta-Antagonists|Angina Pectoris|Coronary Disease|Diagnosis, Differential|Digitalis Glycosides|Ethanol|Exercise Therapy|Humans|Myocardium|Nitroglycerin|Oxygen Consumption|Pain | therapeutic use (0)|diagnosis (0); etiology (0); therapy (1)|complications (0)||therapeutic use (0)|therapeutic use (0)|||metabolism (0)|therapeutic use (0)||diagnosis (0) | 0|0|0|0|0|0|0|0|0|0|0|0 | null | 1976-07-06 | 2019-07-13 | pubmed: 1976-5-1; medline: 1976-5-1 0:1; entrez: 1976-5-1 0:0 | pubmed: 4783; doi: 10.1080/00325481.1976.11714365 | Myocardial Ischemia | ['Angina Pectoris', 'Coronary Disease'] |
4,787 | 1 | [Congenital heart malformations in neonates, infants and young children (author's transl)]. | MEDLINE | Manual | NLM | Congenital heart malformations in neonates, infants and young children represent the main problem of paediatric cardiology in Poland. Congenital cardiovascular diseases (incidence also approximately 8 per 1000 in liveborn infants) cause very high mortality, particularly in the neonatal and infantile period. Approximate... | Problemy medycyny wieku rozwojowego | 0303-2264 | Print | 5 | null | Print | 1,975 | null | null | 191-2 | J Swiderski (J) | Congress (D016423) | null | Age Factors (UI: D000367, Major: No); Child, Preschool (UI: D002675, Major: No); Congresses as Topic (UI: D003226, Major: No); Heart Defects, Congenital (UI: D006330, Major: No) - Qualifiers: diagnosis (UI: Q000175, Major: No); surgery (UI: Q000601, Major: No); therapy (UI: Q000628, Major: Yes); Humans (UI: D006801, Ma... | Age Factors|Child, Preschool|Congresses as Topic|Heart Defects, Congenital|Humans|Infant|Infant, Newborn|Poland | |||diagnosis (0); surgery (0); therapy (1)|||| | 0|0|0|0|0|0|0|0 | null | 1976-07-06 | 2018-12-03 | pubmed: 1975-1-1; medline: 1975-1-1 0:1; entrez: 1975-1-1 0:0 | pubmed: 4787 | Heart Defects, Congenital | [] |
4,896 | 1 | Reduction in myocardial infarct size: prevention of heart cell death. | MEDLINE | Manual | NLM | The course of myocardial necrosis, the clinical syndrome, and methods of treatment are presented. Heart cell death may be prevented by maintaining the balance between myocardial oxygen and energy supply and consumption. New technics of improving this balance by reducing myocardial energy demand, altering metabolism, in... | Southern medical journal | 0038-4348 | Print | 69 | 4 | Print | 1,976 | Apr | null | 442-8 | R J Kones (RJ); J H Phillips (JH) | Journal Article (D016428) | Adrenal Cortex Hormones (Registry: 0, UI: D000305); Adrenergic beta-Antagonists (Registry: 0, UI: D000319); Insulin (Registry: 0, UI: D007328); Vasodilator Agents (Registry: 0, UI: D014665); Hyaluronoglucosaminidase (Registry: EC 3.2.1.35, UI: D006821); Glucose (Registry: IY9XDZ35W2, UI: D005947); Potassium (Registry: ... | Adrenal Cortex Hormones (UI: D000305, Major: No) - Qualifiers: therapeutic use (UI: Q000627, Major: No); Adrenergic beta-Antagonists (UI: D000319, Major: No) - Qualifiers: therapeutic use (UI: Q000627, Major: No); Assisted Circulation (UI: D001243, Major: No); Autolysis (UI: D001329, Major: No) - Qualifiers: drug thera... | Adrenal Cortex Hormones|Adrenergic beta-Antagonists|Assisted Circulation|Autolysis|Cardiac Output|Coronary Circulation|Energy Metabolism|Energy Transfer|Glucose|Humans|Hyaluronoglucosaminidase|Insulin|Myocardial Infarction|Myocardium|Necrosis|Oxygen Consumption|Perfusion|Potassium|Vasodilator Agents | therapeutic use (0)|therapeutic use (0)||drug therapy (0)|drug effects (0)|||drug effects (0)|metabolism (0)||therapeutic use (0)|metabolism (0)|drug therapy (0); metabolism (0); pathology (1)|metabolism (0); pathology (1)||||metabolism (0)|therapeutic use (0) | 0|0|0|0|0|0|1|0|0|0|0|0|0|0|0|0|0|0|0 | null | 1976-07-06 | 2019-07-02 | pubmed: 1976-4-1; medline: 1976-4-1 0:1; entrez: 1976-4-1 0:0 | pubmed: 4896; doi: 10.1097/00007611-197604000-00020 | Myocardial Ischemia | ['Myocardial Infarction'] |
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Insta Learn
1 Dataset Collection
1.1 Name: PubMed25 Cardio
1.2 Cardio Mesh Descriptors (Parents)
- Cerebrovascular Disorders
- Myocardial Ischemia
- Cardiomyopathies
- Arrhythmias, Cardiac
- Heart Valve Diseases
- Heart Defects, Congenital
We thank and acknowledge the contribution of Prof. David Liem for creating and providing the mesh descriptors tree for Cardiovascular Diseases.
1.3 Curation Process
- We downloaded raw xml files from pubmed25
- Total files: 1274 (filename example: pubmed25n0001.xml)
- Total Articles: 38,202,567 (38M)
- We filter articles with abstracts that has matching MeSH Descriptions with Cardio Mesh Descriptors mentioned above
1.4 PubMed 25 Cardio Analytics
- Total Cardio Related Articles: 864244
- Top Journal: The American journal of cardiology (19779 articles)
- More details are covered in the pubmed25_cardio_analytics
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