Data Release 8 now available!
#7
by mlfearon - opened
We have recently updated the data to include 25 more protein kinases critical to drug development for autoimmune diseases, cancers, metabolic disorders, and other pathologies, including:
- PKC family – PKCα, PKCγ, PKCθ, PKN1
- Ribosomal S6 kinases – RSK1, RSK2, RSK3, RSK4, p70S6K
- Cellular stress response – MST2, MSK1, DAPK1, ROS1
- Metabolic & regulatory kinases – YES1, FER, FES, PASK1, CCK2
- Frontier cancer targets – PVK2, SVK, TBK1, CGK2
To date, we have released 420,497 target-compound-mode combinations across 184 targets, including:
- 67 Protein Kinases – Biochemical binding assay for a single mode
- 32 Nuclear Receptors (NRs) – Biochemical assay, agonist and antagonist modes
- 85 7-Transmembrane Receptors (7TMs) – Cell-based assay data for agonist and antagonist modes with cell viability information
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