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In which condition should Physostigmine be avoided? | {"A": "Mechanical intestinal obstruction", "B": "Urinary tract obstruction", "C": "Bronchial asthma", "D": "Parkinson's disease", "E": "All of the above"} | Physostigmine should be avoided in all of the mentioned conditions. It is contraindicated in mechanical intestinal or urinary tract obstruction due to its cholinergic effects that can worsen these conditions. In bronchial asthma, it can cause bronchospasm. For Parkinson's disease, it can exacerbate symptoms due to its ... | contraindications_mcq | hard | contraindications | 2025-09-25T17:44:19.206322 | E |
When is Oxcarbamazepine not safe to use? | {"A": "In patients with known hypersensitivity to carbamazepine", "B": "In patients with a history of bone marrow depression", "C": "In patients with hepatic porphyrias", "D": "In patients with severe renal impairment", "E": "All of the above"} | Oxcarbamazepine is contraindicated in all of these conditions. It should not be used in patients with known hypersensitivity to carbamazepine or oxcarbamazepine, those with a history of bone marrow depression, patients with hepatic porphyrias, and in cases of severe renal impairment. These contraindications are due to ... | contraindications_mcq | hard | contraindications | 2025-09-25T17:45:45.121061 | E |
In which condition should Succinyl Choline Chloride be avoided? | {"A": "Hypokalemia", "B": "Myasthenia gravis", "C": "Glaucoma", "D": "Low serum levels of cholinesterase", "E": "All of the above"} | Succinyl Choline Chloride should be avoided in all the mentioned conditions. Hypokalemia can lead to exaggerated potassium loss with Succinyl Choline. In myasthenia gravis, it can cause prolonged muscle relaxation. Glaucoma patients may experience increased intraocular pressure. Low serum cholinesterase levels can resu... | contraindications_mcq | hard | contraindications | 2025-09-25T17:45:58.013808 | E |
In which condition should Succinyl Choline Chloride be avoided? | {"A": "Hypokalemia", "B": "Myasthenia gravis", "C": "Glaucoma", "D": "Low serum levels of cholinesterase", "E": "All of the above"} | Succinyl Choline Chloride should be avoided in all of the mentioned conditions. Hypokalemia can lead to severe hyperkalemia with Succinyl Choline. In myasthenia gravis, it can cause prolonged paralysis. Glaucoma patients may experience increased intraocular pressure. Low serum cholinesterase levels can result in prolon... | contraindications_mcq | hard | contraindications | 2025-09-25T17:49:16.387499 | E |
When should Glucose NOT be used? | {"A": "Anuria", "B": "Thiamine deficiency", "C": "Intracranial haemorrhage", "D": "Sepsis", "E": "All of the above"} | Glucose should not be used in cases of anuria, thiamine deficiency, intracranial haemorrhage, and sepsis. These conditions can be exacerbated by glucose administration. In anuria, glucose can worsen fluid overload. In thiamine deficiency, glucose can precipitate Wernicke's encephalopathy. In intracranial haemorrhage, g... | contraindications_mcq | hard | contraindications | 2025-09-25T17:49:55.972650 | E |
When should Rifampicin + Isoniazid + Ethambutol NOT be used? | {"A": "In patients with severe liver disease", "B": "In patients with a history of optic neuritis", "C": "In patients with known hypersensitivity to any of the components", "D": "In patients with acute porphyria", "E": "All of the above"} | Rifampicin + Isoniazid + Ethambutol combination should not be used in patients with severe liver disease (due to risk of hepatotoxicity), history of optic neuritis (ethambutol can cause optic neuropathy), known hypersensitivity to any of the components (risk of severe allergic reactions), and acute porphyria (rifampici... | contraindications_mcq | hard | contraindications | 2025-09-25T17:54:53.537132 | E |
When should Rifampicin + Isoniazid + Pyrazinamide + Ethambutol NOT be used? | {"A": "In patients with severe liver disease", "B": "In patients with a history of optic neuritis", "C": "In patients with acute gout", "D": "In patients with known hypersensitivity to any component of the combination", "E": "All of the above"} | Rifampicin + Isoniazid + Pyrazinamide + Ethambutol combination should not be used in patients with severe liver disease due to the hepatotoxic potential of isoniazid, rifampicin, and pyrazinamide. It is contraindicated in patients with a history of optic neuritis because ethambutol can cause optic neuropathy. The combi... | contraindications_mcq | hard | contraindications | 2025-09-25T17:55:48.104190 | E |
What should be monitored when using Domperidone? | {"A": "Potassium levels", "B": "Cardiac rhythm", "C": "Renal function", "D": "Breast tissue changes", "E": "All of the above"} | When using Domperidone, several factors should be monitored: potassium levels (as intravenous administration can lead to hypokalaemia), cardiac rhythm (due to risk of arrhythmias), renal function (as precaution is needed in renal impairment), and breast tissue changes (due to history of breast cancer being a precaution... | precautions_multi_select | hard | precautions | 2025-09-25T17:59:44.773817 | E |
What should patients be careful about when taking Amodiaquine? | {"A": "G-6-PD deficiency", "B": "Concurrent therapy with hepatotoxic drugs", "C": "Pregnancy and lactation", "D": "Signs of blood disorders or hepatitis", "E": "All of the above"} | Patients taking Amodiaquine should be careful about all of these factors. G-6-PD deficiency can increase the risk of hemolysis. Concurrent therapy with hepatotoxic drugs can increase the risk of liver damage. Use during pregnancy and lactation requires caution. Patients should be aware of signs of blood disorders (feve... | precautions_mcq | hard | precautions | 2025-09-25T18:10:00.195123 | E |
What should be monitored when using Ramipril? | {"A": "White blood cell counts in patients with collagen-vascular disease", "B": "Blood pressure in patients with volume depletion", "C": "Potassium levels in patients with diabetes mellitus", "D": "Renal function in patients with impaired kidney function", "E": "All of the above"} | When using Ramipril, several factors need monitoring: 1) White blood cell counts should be considered in patients with collagen-vascular disease, especially if associated with impaired renal function. 2) Blood pressure should be monitored in patients with volume depletion, as they are at risk of symptomatic hypotension... | precautions_mcq | hard | precautions | 2025-09-25T18:15:08.206293 | E |
What should be monitored when using Metoprolol? | {"A": "Lung function in patients with obstructive airways disease", "B": "Liver function in patients with portal hypertension", "C": "Blood glucose levels in diabetic patients", "D": "Thyroid function tests", "E": "All of the above"} | When using Metoprolol, multiple factors should be monitored: lung function in patients with obstructive airways disease (introduce cautiously), liver function in patients with portal hypertension (risk of deterioration), blood glucose levels in diabetic patients (symptoms of hypoglycemia may be masked), and thyroid fun... | precautions_mcq | hard | precautions | 2025-09-25T18:16:06.835796 | E |
What is the maximum daily dose of Heparin for an adult? | {"A": "5,000 units", "B": "10,000 units", "C": "20,000 units", "D": "40,000 units", "E": "There is no maximum daily dose limit"} | Heparin does not have a fixed maximum daily dose limit for adults. The dosage is adjusted based on the patient's weight, clinical condition, and coagulation test results. Doses can range from low prophylactic doses to high therapeutic doses, and can exceed 40,000 units per day in some cases. The dose is individualized ... | dose_mcq | hard | dose | 2025-09-25T18:21:53.355806 | E |
What pregnancy category does Iron Salts belong to? | {"A": "Category A for all Iron Salts", "B": "Category B for all Iron Salts", "C": "Category C for all Iron Salts", "D": "Varies depending on the specific Iron Salt", "E": "None of the above"} | The pregnancy category for Iron Salts varies depending on the specific formulation. Ferrous Gluconate and Ferrous Sulphate are Category A, meaning controlled studies show no risk to the fetus. Iron Sucrose and Sodium Ferric Gluconate are Category B, indicating no demonstrated risk in animal studies but lack of controll... | pregnancy_safety_mcq | hard | pregnancy_category | 2025-09-25T18:44:03.087574 | D |
Under which schedule is Gamma Benzene Hexachloride classified? | {"A": "Schedule H", "B": "Schedule X", "C": "Schedule G", "D": "Schedule K", "E": "None of the above"} | Gamma Benzene Hexachloride is not classified under any of the mentioned schedules in the National Formulary of India. It is actually banned for manufacture, sale, and distribution in India due to its potential health and environmental hazards. | schedule_mcq | hard | schedule | 2025-09-25T18:59:05.733531 | E |
For which conditions is Tacrolimus used? | {"A": "Prophylaxis of organ rejection in liver transplants", "B": "Prophylaxis of organ rejection in kidney transplants", "C": "Prophylaxis of organ rejection in heart transplants", "D": "Treatment of atopic dermatitis", "E": "All of the above"} | Tacrolimus is used for prophylaxis of organ rejection in patients receiving allogeneic liver, kidney, or heart transplants. Additionally, Tacrolimus ointment is indicated for the treatment of atopic dermatitis and psoriasis. | indications_multi_select | medium | indications | 2025-09-25T17:38:12.448486 | E |
When should Benzathine Benzyl Penicillin NOT be used? | {"A": "In patients with hypersensitivity to penicillin", "B": "In patients with neurosyphilis", "C": "In patients with streptococcal infections", "D": "In patients with rheumatic fever", "E": "All of the above"} | Benzathine Benzyl Penicillin is contraindicated in patients with hypersensitivity to penicillin due to the risk of severe allergic reactions. It is also not recommended for use in neurosyphilis because it does not achieve adequate concentrations in the cerebrospinal fluid. The drug can be used for streptococcal infecti... | contraindications_multi_select | medium | contraindications | 2025-09-25T17:53:59.791460 | A, B |
When should Insulin NOT be used? | {"A": "During episodes of hypoglycemia", "B": "In patients with known hypersensitivity to insulin", "C": "In patients with type 1 diabetes", "D": "During pregnancy", "E": "None of the above"} | Insulin should not be used during episodes of hypoglycemia (low blood sugar) as it would further lower blood glucose levels, potentially leading to severe hypoglycemia. It is also contraindicated in patients with known hypersensitivity to insulin or any of its excipients, as it could cause allergic reactions. Insulin i... | contraindications_multi_select | medium | contraindications | 2025-09-25T17:56:11.219524 | A, B |
What should patients be careful about when taking Memantine? | {"A": "History of seizures", "B": "Increased urine pH", "C": "Pregnancy", "D": "Lactation", "E": "All of the above"} | Patients should be careful about all of these factors when taking Memantine. The drug requires precautions in patients with a history of seizures, as it may increase seizure risk. Increased urine pH can result in higher plasma levels of Memantine. Use during pregnancy (Appendix 7c) and lactation requires caution. Addit... | precautions_multi_select | medium | precautions | 2025-09-25T17:59:25.130990 | E |
What should be monitored when using Telmisartan? | {"A": "Serum potassium levels", "B": "Blood pressure", "C": "Renal function", "D": "A and B only", "E": "A, B, and C"} | When using Telmisartan, it is important to monitor serum potassium levels, blood pressure, and renal function. Telmisartan can affect potassium levels, is used to treat hypertension, and may impact kidney function, especially in patients with renal artery stenosis. | precautions_multi_select | medium | precautions | 2025-09-25T18:00:02.278899 | E |
What should patients be careful about when taking Nalidixic Acid? | {"A": "Exposure to excessive sunlight", "B": "Monitoring blood counts if treatment exceeds 2 weeks", "C": "Risk of tendon damage", "D": "False positive urinary glucose tests", "E": "All of the above"} | Patients taking Nalidixic Acid should be careful about all of these factors. They should avoid exposure to excessive sunlight due to the risk of photosensitivity. Blood counts, renal and liver function should be monitored if treatment exceeds 2 weeks. There is a rare risk of tendon damage, and the drug should be discon... | precautions_multi_select | medium | precautions | 2025-09-25T18:00:10.182837 | E |
What should be monitored when using Enalapril? | {"A": "Renal function", "B": "Blood pressure", "C": "Potassium levels", "D": "A and B only", "E": "A, B, and C"} | When using Enalapril, it is important to monitor renal function, blood pressure, and potassium levels. Renal function should be monitored before and during treatment, especially in patients with renal impairment. Blood pressure monitoring is crucial, particularly with the first doses, as there is a risk of hypotension.... | precautions_multi_select | medium | precautions | 2025-09-25T18:00:29.214519 | E |
What should patients be careful about when using Tuberculin Purified Protein Derivative (Tuberculin PPD)? | {"A": "Avoid contact with open cuts, abraded or diseased skin, eyes or mouth", "B": "Increased sensitivity in elderly patients", "C": "Decreased sensitivity in patients with malnutrition", "D": "Diminished sensitivity in patients with viral or bacterial infections", "E": "All of the above"} | All of these precautions apply to Tuberculin PPD use. Patients should avoid contact with open cuts, abraded or diseased skin, eyes or mouth. Elderly patients may have increased sensitivity. Patients with malnutrition, viral or bacterial infections (including HIV and severe tuberculosis), malignant disease, or those on ... | precautions_multi_select | medium | precautions | 2025-09-25T18:00:53.543756 | E |
What should be monitored when using Isophane Insulin? | {"A": "Blood glucose levels", "B": "Kidney function", "C": "Injection site reactions", "D": "Liver enzymes", "E": "All of the above"} | When using Isophane Insulin, it is important to monitor blood glucose levels to ensure proper dosing and glycemic control. Kidney function should be monitored as the dose may need to be reduced in renal impairment. Injection site reactions should also be monitored to prevent complications. Liver enzyme monitoring is no... | precautions_multi_select | medium | precautions | 2025-09-25T18:00:59.222196 | A, B, C |
What should patients be careful about when taking Iron Salts? | {"A": "Monitor for signs of hypersensitivity for at least 1 hour after test dose", "B": "Do not use for longer than 6 months", "C": "Use caution in patients with peptic ulcer", "D": "Use caution in patients with ulcerative colitis", "E": "All of the above"} | Patients taking Iron Salts should be careful about all of these aspects. A test dose of 0.5 ml should be given and the patient observed for at least 1 hour for signs of hypersensitivity. Iron Salts should not be administered for longer than 6 months. Caution is needed in patients with peptic ulcer and ulcerative coliti... | precautions_multi_select | medium | precautions | 2025-09-25T18:01:56.952547 | E |
What should patients be careful about when using Calamine? | {"A": "Avoid contact with eyes and mucous membranes", "B": "Do not apply to broken or oozing skin", "C": "Shake well before use", "D": "Do not use on large areas of the body", "E": "All of the above"} | When using Calamine, patients should be careful about all the mentioned precautions. They should avoid contact with eyes and mucous membranes, not apply it to broken or oozing skin, shake the product well before use, and avoid using it on large areas of the body. These precautions help ensure safe and effective use of ... | precautions_multi_select | medium | precautions | 2025-09-25T18:02:02.927749 | E |
What should patients be careful about when taking Thalidomide? | {"A": "Contraception use before, during, and after therapy", "B": "Blood or sperm donation during therapy", "C": "Driving or operating complex machinery", "D": "Alcohol consumption", "E": "All of the above"} | Patients taking Thalidomide should be careful about all of these aspects. Adequate contraception is required before, during, and for at least 4 weeks after therapy due to the drug's teratogenic effects. Blood or sperm donation is prohibited during therapy. Thalidomide can impair mental and physical abilities required f... | precautions_multi_select | medium | precautions | 2025-09-25T18:02:21.334836 | E |
What should patients be careful about when taking Pyrantel Pamoate? | {"A": "Pregnancy", "B": "Liver disease", "C": "Severe malnutrition", "D": "Concurrent administration with piperazine", "E": "All of the above"} | Patients should be careful about all of these factors when taking Pyrantel Pamoate. It requires caution during pregnancy (Appendix 7c), in liver disease (dose reduction may be necessary), in cases of severe malnutrition, and when administered concurrently with piperazine. Additionally, caution is needed in patients wit... | precautions_multi_select | medium | precautions | 2025-09-25T18:03:30.290605 | E |
What precautions should be taken when using Dithranol? | {"A": "Avoid contact with eyes and healthy skin", "B": "Do not use in acute psoriasis", "C": "Use with caution during pregnancy", "D": "A and B only", "E": "A, B, and C"} | Dithranol is an irritant and should be avoided on eyes and healthy skin. It is not to be used in acute psoriasis. Caution is advised during pregnancy (Appendix 7c). All these precautions are important when using Dithranol. | precautions_multi_select | medium | precautions | 2025-09-25T18:03:49.596238 | E |
What should be monitored when using Cyclophosphamide? | {"A": "Renal function", "B": "Hepatic function", "C": "Blood counts", "D": "A and B only", "E": "A, B, and C"} | When using Cyclophosphamide, it is important to monitor renal function, hepatic function, and blood counts. Cyclophosphamide can cause renal toxicity, hepatotoxicity, and bone marrow suppression. Regular monitoring of these parameters helps detect potential adverse effects early and allows for appropriate dose adjustme... | precautions_multi_select | medium | precautions | 2025-09-25T18:04:16.051065 | E |
What should patients be careful about when taking Ascorbic Acid (Vitamin C)? | {"A": "Acetylsalicylic acid hypersensitivity", "B": "G-6-PD deficiency", "C": "Risk of renal calcium oxalate calculi with large doses", "D": "Pregnancy", "E": "All of the above"} | Patients should be careful about all of these factors when taking Ascorbic Acid (Vitamin C). It should be used with caution in patients with acetylsalicylic acid hypersensitivity and G-6-PD deficiency. Large doses may cause renal calcium oxalate calculi. Special precautions are also necessary during pregnancy. | precautions_multi_select | medium | precautions | 2025-09-25T18:05:18.722942 | E |
What should be monitored when using Calcium Disodium Edetate? | {"A": "Urine output", "B": "Renal function", "C": "Intracranial pressure in patients with lead encephalopathy", "D": "A and B", "E": "All of the above"} | When using Calcium Disodium Edetate, it is important to monitor urine output to ensure adequate elimination of the drug and chelated metals. Renal function should be monitored, especially in patients with pre-existing mild renal disease. In patients with lead encephalopathy and cerebral edema, intracranial pressure sho... | precautions_multi_select | medium | precautions | 2025-09-25T18:05:31.552902 | E |
What should be monitored when using Pyrazinamide? | {"A": "Hepatic function", "B": "Blood glucose levels", "C": "Uric acid levels", "D": "A and B only", "E": "A, B, and C"} | When using Pyrazinamide, hepatic function, blood glucose levels, and uric acid levels should be monitored. Pyrazinamide can cause hepatotoxicity, so liver function tests are essential. In patients with diabetes, blood glucose levels may change suddenly. Pyrazinamide can also cause hypouricemia, necessitating monitoring... | precautions_multi_select | medium | precautions | 2025-09-25T18:05:37.046143 | E |
What should be monitored when using Desferrioxamine Mesylate? | {"A": "Eye and ear function", "B": "Renal function", "C": "Growth in children under 3 years", "D": "A and B only", "E": "A, B, and C"} | When using Desferrioxamine Mesylate, eye and ear examinations should be conducted before and at 3-month intervals during treatment. Renal function should be monitored due to the risk of impairment. In children under 3 years, growth should be monitored as Desferrioxamine Mesylate may retard growth. | precautions_multi_select | medium | precautions | 2025-09-25T18:05:43.564363 | E |
What precautions should be taken when using Anti-D Immunoglobulin (Human)? | {"A": "Use with caution in rhesus-positive patients for treatment of blood disorders", "B": "Use with caution in rhesus-negative patients with anti-D antibodies in their serum", "C": "Observe patients for 20 minutes after injection", "D": "A and B only", "E": "A, B, and C"} | When using Anti-D Immunoglobulin (Human), three key precautions should be taken: 1) Use with caution in rhesus-positive patients for treatment of blood disorders, 2) Use with caution in rhesus-negative patients with anti-D antibodies in their serum, and 3) Observe patients for 20 minutes after injection. These precauti... | precautions_multi_select | medium | precautions | 2025-09-25T18:05:51.156029 | E |
What should patients be careful about when using Formaldehyde? | {"A": "Applying to large areas of skin", "B": "Using on the face or anogenital region", "C": "Applying to broken skin", "D": "Using in patients with diabetes", "E": "All of the above"} | Patients should be careful about all of these when using Formaldehyde. It should not be applied to large areas of skin, the face, or anogenital region. Application to broken skin should be avoided. Patients with diabetes are at risk of neuropathic ulcers and require extra caution. Additionally, surrounding skin should ... | precautions_multi_select | medium | precautions | 2025-09-25T18:06:31.470421 | E |
What should patients be careful about when using Framycetin? | {"A": "Prolonged use", "B": "Application on large areas in children, elderly, and patients with renal failure", "C": "Use during pregnancy", "D": "Potential drug interactions", "E": "All of the above"} | Patients should be careful about all the mentioned aspects when using Framycetin. Prolonged use should be avoided. There is a risk of ototoxicity due to systemic absorption if applied on large areas in children, elderly, and patients with renal failure. Caution is advised during pregnancy. Potential drug interactions s... | precautions_multi_select | medium | precautions | 2025-09-25T18:07:10.303683 | E |
What should patients be careful about when taking BCG Vaccine? | {"A": "Eczema or scabies at the vaccine site", "B": "Severe immunocompromise", "C": "Pregnancy", "D": "A and B only", "E": "A, B, and C"} | Patients should be careful about BCG Vaccine use in the following situations: 1) Eczema or scabies at the vaccine site - the site must be lesion-free. 2) Severe immunocompromise - BCG is a live vaccine and can cause complications in immunocompromised patients. 3) Pregnancy - BCG vaccine use requires caution during preg... | precautions_multi_select | medium | precautions | 2025-09-25T18:07:16.287742 | E |
What should be monitored when using Famotidine? | {"A": "Renal function", "B": "Liver function", "C": "Possibility of gastric malignancy", "D": "A and B", "E": "A, B, and C"} | When using Famotidine, several factors should be monitored: renal function, as the drug requires dose adjustment in impaired renal function; liver function, especially in patients with liver cirrhosis; and the possibility of gastric malignancy should be excluded before starting treatment. Additionally, special care sho... | precautions_multi_select | medium | precautions | 2025-09-25T18:07:29.306128 | E |
What warnings apply to Activated Charcoal use? | {"A": "Risk of aspiration in drowsy or unconscious patients", "B": "Not effective for poisoning with alcohols and cyanides", "C": "Ineffective for poisoning with iron and lithium salts", "D": "A and B only", "E": "A, B, and C"} | Activated Charcoal use has several important warnings: 1) There is a risk of aspiration in drowsy or unconscious patients, so intubation before administration via nasogastric or gastric tube may be necessary. 2) It is not effective for poisoning with alcohols, clofenotane (DDT), and cyanides. 3) It is also ineffective ... | precautions_multi_select | medium | precautions | 2025-09-25T18:07:35.906869 | E |
What should be prepared when administering Antivenom Sera? | {"A": "Resuscitation facilities", "B": "Antihistamine", "C": "Treatment for anaphylactic shock", "D": "A and B only", "E": "A, B, and C"} | When administering Antivenom Sera, resuscitation facilities should be immediately available, and both antihistamine and treatment for anaphylactic shock should be kept ready. This is due to the potential risk of severe allergic reactions to the antivenom. | precautions_multi_select | medium | precautions | 2025-09-25T18:07:48.279833 | E |
What should be monitored when using Glucose? | {"A": "Fluid balance", "B": "Insulin requirements in diabetic patients", "C": "Electrolyte levels", "D": "A and B only", "E": "A, B, and C"} | When using Glucose, it is important to monitor fluid balance, insulin requirements in diabetic patients, and electrolyte levels. Glucose administration can affect fluid balance, especially when used with mannitol. In diabetic patients, additional insulin may be required. Electrolyte imbalances, particularly in sodium a... | precautions_multi_select | medium | precautions | 2025-09-25T18:08:45.279172 | E |
What should patients be careful about when taking Nalidixic Acid? | {"A": "Exposure to excessive sunlight", "B": "History of epilepsy or seizure-prone conditions", "C": "G-6-PD deficiency", "D": "Myasthenia gravis", "E": "All of the above"} | Patients taking Nalidixic Acid should be careful about all of these factors. Excessive sunlight exposure can cause photosensitivity reactions. Those with a history of epilepsy or seizure-prone conditions are at increased risk of seizures. G-6-PD deficiency patients may experience hemolysis. Myasthenia gravis can be exa... | precautions_multi_select | medium | precautions | 2025-09-25T18:08:57.356550 | E |
What should be monitored when using Timolol? | {"A": "Risk of keratitis in older patients", "B": "Use with a miotic in angle-closure glaucoma", "C": "Potential drug interactions", "D": "Safety during pregnancy", "E": "All of the above"} | When using Timolol, all of these factors should be monitored. Older people are at risk of keratitis. In angle-closure glaucoma, Timolol should be used with a miotic, not alone. Potential drug interactions should be checked (Appendix 6c). Safety during pregnancy should be considered (Appendix 7c). | precautions_multi_select | medium | precautions | 2025-09-25T18:09:10.644268 | E |
What should patients be careful about when taking Phenoxymethyl Penicillin (Penicillin V)? | {"A": "History of allergy to penicillins", "B": "Breastfeeding", "C": "Pregnancy", "D": "Potential interactions with other medications", "E": "All of the above"} | Patients should be careful about all of these factors when taking Phenoxymethyl Penicillin (Penicillin V). A history of allergy to penicillins is a significant precaution due to the risk of severe allergic reactions. The drug can be excreted in breast milk, so caution is needed during lactation. Use during pregnancy sh... | precautions_multi_select | medium | precautions | 2025-09-25T18:09:34.958182 | E |
What should patients be careful about when taking Mifepristone + Misoprostol? | {"A": "Presence of an IUD", "B": "History of asthma or chronic obstructive pulmonary disease", "C": "Alcoholism", "D": "Prosthetic heart valve or infective endocarditis", "E": "All of the above"} | Patients should be careful about all these conditions when taking Mifepristone + Misoprostol. The presence of an IUD, history of asthma or COPD, alcoholism, and prosthetic heart valve or infective endocarditis are all important precautions to consider. These conditions may increase the risk of complications or affect t... | precautions_multi_select | medium | precautions | 2025-09-25T18:11:09.281468 | E |
What precautions should be taken when using Anti-D Immunoglobulin (Human)? | {"A": "Use with caution in rhesus-positive patients for treatment of blood disorders", "B": "Use with caution in rhesus-negative patients with anti-D antibodies in their serum", "C": "Observe patients for 20 minutes after injection", "D": "A and B only", "E": "A, B, and C"} | Anti-D Immunoglobulin (Human) requires several precautions: 1) It should be used with caution in rhesus-positive patients when treating blood disorders. 2) Caution is needed in rhesus-negative patients who have anti-D antibodies in their serum. 3) Patients must be observed for 20 minutes after injection to monitor for ... | precautions_multi_select | medium | precautions | 2025-09-25T18:12:05.858420 | E |
What should be monitored when using Etoposide? | {"A": "Liver function", "B": "Kidney function", "C": "Drug interactions", "D": "A and B only", "E": "A, B, and C"} | When using Etoposide, it is important to monitor liver function (hepatic impairment), kidney function (renal impairment), and potential drug interactions. The National Formulary of India specifically mentions monitoring for hepatic impairment (Appendix 7a), renal impairment (Appendix 7d), and drug interactions (Appendi... | precautions_multi_select | medium | precautions | 2025-09-25T18:12:24.784711 | E |
What should patients be careful about when taking Haloperidol? | {"A": "Performing skilled tasks like driving or operating machinery", "B": "Abrupt withdrawal of the medication", "C": "Exposure to very hot or very cold weather, especially in elderly patients", "D": "Lying down for 30 minutes after intramuscular injection", "E": "All of the above"} | Patients taking Haloperidol should be careful about all the mentioned aspects. The drug may impair the ability to perform skilled tasks like driving. Abrupt withdrawal should be avoided. Elderly patients should be cautious in extreme temperatures. Patients should remain supine for 30 minutes after intramuscular injecti... | precautions_multi_select | medium | precautions | 2025-09-25T18:12:57.181246 | E |
What should patients be careful about when taking Cefixime? | {"A": "History of allergy to penicillins", "B": "Renal failure", "C": "Gastrointestinal disease", "D": "Pregnancy and lactation", "E": "All of the above"} | Patients should be careful about all of these factors when taking Cefixime. Those with a history of penicillin allergy may have cross-sensitivity. Renal failure patients may need dose adjustments. Gastrointestinal disease patients may experience worsened symptoms. Pregnant and lactating women should use Cefixime with c... | precautions_multi_select | medium | precautions | 2025-09-25T18:13:03.706310 | E |
What should be monitored when using Diltiazem? | {"A": "Liver function", "B": "Kidney function", "C": "Heart rate", "D": "PR interval on ECG", "E": "All of the above"} | When using Diltiazem, all of these parameters should be monitored. Diltiazem requires dose reduction in hepatic and renal impairment, so liver and kidney function need monitoring. It can cause bradycardia and should be avoided in severe cases, necessitating heart rate monitoring. Diltiazem can also prolong the PR inter... | precautions_multi_select | medium | precautions | 2025-09-25T18:13:26.993478 | E |
What should patients be careful about when taking Atorvastatin? | {"A": "Consuming substantial quantities of alcohol", "B": "Having a history of liver diseases", "C": "Children below 10 years of age", "D": "Premenarcheal females", "E": "All of the above"} | Patients should be careful about all the mentioned factors when taking Atorvastatin. The drug requires caution in patients who consume substantial quantities of alcohol and have a history of liver diseases. It is also not recommended for children below 10 years of age and premenarcheal females. Additionally, potential ... | precautions_multi_select | medium | precautions | 2025-09-25T18:13:44.550227 | E |
What should be monitored when using Etoposide? | {"A": "Liver function", "B": "Kidney function", "C": "Drug interactions", "D": "A and B only", "E": "A, B, and C"} | When using Etoposide, it is important to monitor liver function (due to potential hepatic impairment), kidney function (due to potential renal impairment), and drug interactions. The National Formulary of India specifically mentions hepatic impairment (Appendix 7a), renal impairment (Appendix 7d), and interactions (App... | precautions_multi_select | medium | precautions | 2025-09-25T18:13:50.168215 | E |
What should be monitored when using Enalapril? | {"A": "Renal function", "B": "Blood pressure", "C": "Potassium levels", "D": "A and B only", "E": "A, B, and C"} | When using Enalapril, it is important to monitor renal function, blood pressure, and potassium levels. Renal function should be monitored before and during treatment, especially in patients with renal impairment. Blood pressure monitoring is crucial, particularly with the first doses, as there is a risk of hypotension.... | precautions_multi_select | medium | precautions | 2025-09-25T18:14:01.847645 | E |
What should patients be careful about when using Framycetin? | {"A": "Prolonged use", "B": "Application on large areas in children, elderly, and patients with renal failure", "C": "Use during pregnancy", "D": "Potential drug interactions", "E": "All of the above"} | Patients should be careful about all the mentioned aspects when using Framycetin. Prolonged use should be avoided. Application on large areas in children, elderly, and patients with renal failure may lead to ototoxicity due to systemic absorption. Use during pregnancy requires caution. Potential drug interactions shoul... | precautions_multi_select | medium | precautions | 2025-09-25T18:14:08.336944 | E |
What should be monitored when using Digoxin? | {"A": "Serum potassium levels", "B": "Renal function", "C": "Thyroid function", "D": "Cardiac rhythm", "E": "All of the above"} | When using Digoxin, it is important to monitor serum potassium levels (to avoid hypokalaemia), renal function (as dose adjustment is needed in renal impairment), thyroid function (as thyroid disease affects Digoxin metabolism), and cardiac rhythm (to detect any dysrhythmias). All these factors are crucial for safe and ... | precautions_multi_select | medium | precautions | 2025-09-25T18:14:33.180531 | E |
What should patients be careful about when taking Isosorbide Dinitrate? | {"A": "Severe hepatic or renal impairment", "B": "Hypothyroidism", "C": "Recent history of myocardial infarction", "D": "Pregnancy", "E": "All of the above"} | Patients should be careful about all the mentioned conditions when taking Isosorbide Dinitrate. The drug requires precautions in cases of severe hepatic or renal impairment, hypothyroidism, recent history of myocardial infarction, and during pregnancy. These conditions may increase the risk of adverse effects or alter ... | precautions_multi_select | medium | precautions | 2025-09-25T18:14:50.523179 | E |
What should patients be careful about when using Salicylic Acid? | {"A": "Applying to large areas of skin", "B": "Using on irritated or infected skin", "C": "Contact with eyes and mucous membranes", "D": "Using if they have diabetes mellitus", "E": "All of the above"} | Patients should be careful about all these aspects when using Salicylic Acid. It should not be applied to large areas of skin, irritated or infected skin, or come in contact with eyes and mucous membranes. Patients with diabetes mellitus should also use it with caution due to potential effects on peripheral blood circu... | precautions_multi_select | medium | precautions | 2025-09-25T18:15:14.491433 | E |
What should be monitored when using Procainamide? | {"A": "Blood count", "B": "ECG", "C": "Electrolyte balance", "D": "A and B only", "E": "A, B, and C"} | When using Procainamide, it is important to monitor blood count, ECG, and electrolyte balance. Regular monitoring of these parameters helps detect potential adverse effects and ensures safe use of the medication, especially in patients with renal or hepatic impairment, heart conditions, or blood disorders. | precautions_multi_select | medium | precautions | 2025-09-25T18:16:00.740393 | E |
What is the initial daily dose of Fenofibrate for an adult with hyperlipidemia? | {"A": "67 mg once daily", "B": "67 mg 2-4 times a day (micronized)", "C": "200 mg once daily", "D": "200 mg/day in divided doses (non-micronized)", "E": "400 mg once daily"} | The initial dose of Fenofibrate for adults with hyperlipidemia is 67 mg 2-4 times a day for the micronized form, or 200 mg/day in divided doses for the non-micronized form. Both options B and D are correct, as they represent the initial dosing for different formulations of Fenofibrate. | dose_multi_select | medium | dose | 2025-09-25T18:22:15.973937 | B, D |
In which condition should Pyrantel Pamoate be avoided? | {"A": "Liver disease", "B": "Kidney disease", "C": "Heart disease", "D": "Lung disease", "E": "None of the above"} | Pyrantel Pamoate should be avoided in patients with liver disease. The drug is metabolized in the liver, and hepatic impairment can lead to increased drug levels and potential toxicity. There are no specific contraindications for kidney disease, heart disease, or lung disease with Pyrantel Pamoate. | contraindications_mcq | medium | contraindications | 2025-09-25T17:49:10.749911 | A |
How much Sulphacetamide should be instilled in the infected eye? | {"A": "1 drop once daily", "B": "2 to 3 drops 4 to 5 times a day", "C": "5 drops every 2 hours", "D": "1 drop every hour", "E": "10 drops twice daily"} | The correct dosage for Sulphacetamide is to instill 2 to 3 drops in the infected eye 4 to 5 times a day or as required. This dosage ensures proper concentration of the medication in the eye for effective treatment of the infection. | dose_mcq | medium | dose | 2025-09-25T18:22:03.978020 | B |
What is Cefixime used to treat? | {"A": "Otitis media", "B": "Respiratory tract infections", "C": "Uncomplicated urinary tract infections", "D": "Infections caused by Enterobacteriaceae", "E": "All of the above"} | Cefixime is used to treat all of the mentioned conditions. It is effective against otitis media, respiratory tract infections, uncomplicated urinary tract infections, and infections caused by Enterobacteriaceae. Additionally, it is also effective against infections caused by H. influenzae species. | indications_mcq | medium | indications | 2025-09-25T17:28:37.481501 | E |
What should patients be careful about when taking Sodium Lactate? | {"A": "Impaired renal function", "B": "Cardiac failure", "C": "Hypertension", "D": "Toxaemia of pregnancy", "E": "All of the above"} | Patients should be careful when taking Sodium Lactate if they have impaired renal function, cardiac failure, hypertension, or toxaemia of pregnancy. These conditions require restricted intake of Sodium Lactate. Additionally, caution is needed in cases of peripheral and pulmonary oedema, corticosteroid therapy, shock, a... | precautions_mcq | medium | precautions | 2025-09-25T18:09:28.204542 | E |
What pregnancy category does Diethylcarbamazine belong to? | {"A": "Category A", "B": "Category B", "C": "Category C", "D": "Category D", "E": "Category X"} | Diethylcarbamazine belongs to Pregnancy Category C. This means that either studies in animals have revealed adverse effects on the fetus (teratogenic or embryocidal or other) and there are no controlled studies in women, or studies in women and animals are not available. Drugs in this category should be given only if t... | pregnancy_category_mcq | medium | pregnancy_category | 2025-09-25T18:34:50.699081 | C |
Under which schedule is Tenofovir classified? | {"A": "Schedule H", "B": "Schedule X", "C": "Schedule G", "D": "Schedule K", "E": "None of the above"} | Tenofovir is classified under Schedule H in the National Formulary of India. Schedule H drugs can only be dispensed on the prescription of a registered medical practitioner and require a special license for sale. | schedule_mcq | medium | schedule | 2025-09-25T18:52:14.475130 | A |
In which condition should Quinine be avoided? | {"A": "Haemoglobinuria", "B": "Malaria", "C": "Hypertension", "D": "Diabetes", "E": "None of the above"} | Quinine is contraindicated in patients with haemoglobinuria. Other contraindications include optic neuritis, tinnitus, quinine-resistant falciparum malaria, pregnancy, lactation, and prolonged QT interval. Haemoglobinuria is a serious condition where the use of quinine can potentially worsen the patient's condition. | contraindications_mcq | medium | contraindications | 2025-09-25T17:56:54.193761 | A |
What is the recommended intravenous dose of Thiopental for an adult over 18 years who is fit and premedicated? | {"A": "3 to 5 mg/kg", "B": "10 to 150 mg", "C": "4 to 7 mg/kg", "D": "2.5 to 5 mg/kg", "E": "150 to 300 mg"} | For an adult over 18 years who is fit and premedicated, the recommended intravenous dose of Thiopental is 10 to 150 mg. This is administered as a slow intravenous injection of a 2.5% solution. | dose_mcq | medium | dose | 2025-09-25T18:18:08.132468 | B |
What is L- Asparaginase used to treat? | {"A": "Acute lymphoblastic leukaemia", "B": "Chronic myeloid leukaemia", "C": "Non-Hodgkin's lymphoma", "D": "Multiple myeloma", "E": "None of the above"} | L-Asparaginase is specifically used in the treatment of acute lymphoblastic leukaemia. It works by depleting asparagine, an amino acid essential for leukemic cell growth, thereby inhibiting protein synthesis and cell proliferation in these cancer cells. | indications_mcq | medium | indications | 2025-09-25T17:38:02.681979 | A |
What should patients be careful about when using Tolnaftate? | {"A": "Avoid contact with eyes and mucous membranes", "B": "Be aware of potential mixed infections", "C": "Discontinue if irritation occurs on application", "D": "Use with caution during pregnancy", "E": "All of the above"} | Patients using Tolnaftate should be careful about all of these precautions. They should avoid contact with eyes and mucous membranes, be aware of potential mixed infections, discontinue use if irritation occurs on application, and use with caution during pregnancy. These precautions help ensure safe and effective use o... | precautions_mcq | medium | precautions | 2025-09-25T18:01:11.556666 | E |
What pregnancy category does Rubella Vaccine belong to? | {"A": "Category A", "B": "Category B", "C": "Category C", "D": "Category D", "E": "Category X"} | Rubella Vaccine belongs to Pregnancy Category X. This means that studies in animals or humans have demonstrated fetal abnormalities, or there is evidence of fetal risk based on human experience. The risk of using Rubella Vaccine in pregnant women clearly outweighs any possible benefit. The vaccine is contraindicated in... | pregnancy_category_mcq | medium | pregnancy_category | 2025-09-25T18:46:00.569365 | E |
Under which schedule is Intraperitoneal Dialysis Solution classified? | {"A": "Schedule H", "B": "Schedule X", "C": "Schedule G", "D": "Schedule K", "E": "None of the above"} | Intraperitoneal Dialysis Solution is not classified under any controlled substance schedule in India. It is a medical solution used for dialysis and does not have potential for abuse or addiction, which are typically characteristics of scheduled drugs. | schedule_mcq | medium | schedule | 2025-09-25T19:03:17.643129 | E |
When should Haemophilus Influenza Type B Vaccine NOT be used? | {"A": "In patients with severe allergic reaction to any component of the vaccine", "B": "In patients with mild fever", "C": "In patients with a history of seizures", "D": "In patients with mild respiratory infections", "E": "None of the above"} | Haemophilus Influenza Type B Vaccine is contraindicated in patients with a severe allergic reaction to any component of the vaccine. Mild fever, history of seizures, and mild respiratory infections are not contraindications for this vaccine. | contraindications_mcq | medium | contraindications | 2025-09-25T17:57:05.714457 | A |
What is the recommended oral dose of Amodiaquine for adult prophylaxis against malaria? | {"A": "150 mg once weekly", "B": "300 mg once weekly", "C": "600 mg once weekly", "D": "300 mg daily", "E": "None of the above"} | For adult prophylaxis against malaria, the recommended oral dose of Amodiaquine is 300 mg once weekly. This regimen should start one week before entering the endemic area and continue for 4 weeks after leaving. | dose_mcq | medium | dose | 2025-09-25T18:25:49.600605 | B |
What is Pyridoxine used to treat? | {"A": "Pyridoxine deficiency due to metabolic disorders", "B": "Isoniazid-induced neuropathy", "C": "Sideroblastic anaemia", "D": "Thiamine deficiency", "E": "A, B, and C"} | Pyridoxine is used to treat pyridoxine deficiency due to metabolic disorders, isoniazid-induced neuropathy, and sideroblastic anaemia. Thiamine deficiency is not treated with Pyridoxine, but with Thiamine itself. | indications_mcq | medium | indications | 2025-09-25T17:36:19.306709 | E |
What should patients be careful about when taking Glucose + Sodium Chloride? | {"A": "Impaired renal function", "B": "Cardiac failure", "C": "Hypertension", "D": "Toxaemia of pregnancy", "E": "All of the above"} | Patients should be careful when taking Glucose + Sodium Chloride if they have impaired renal function, cardiac failure, hypertension, peripheral and pulmonary oedema, or toxaemia of pregnancy. In these conditions, intake of Glucose + Sodium Chloride should be restricted due to potential risks associated with fluid and ... | precautions_mcq | medium | precautions | 2025-09-25T18:10:35.906211 | E |
What pregnancy category does Sodium Lactate belong to? | {"A": "Category A", "B": "Category B", "C": "Category C", "D": "Category D", "E": "None of the above"} | Sodium Lactate does not have a specific pregnancy category assigned to it in the National Formulary of India. It is generally considered safe for use during pregnancy when clinically indicated, but as with all medications, it should be used with caution and only when the potential benefits outweigh the risks. The lack ... | pregnancy_category_mcq | medium | pregnancy_category | 2025-09-25T18:33:01.546359 | E |
Under which schedule is Magnesium Sulphate classified? | {"A": "Schedule H", "B": "Schedule X", "C": "Schedule G", "D": "Schedule K", "E": "None of the above"} | Magnesium Sulphate is classified under Schedule H in the National Formulary of India. Schedule H drugs can only be dispensed on the prescription of a registered medical practitioner. | schedule_mcq | medium | schedule | 2025-09-25T18:52:03.744508 | A |
In which condition should Urea NOT be used? | {"A": "Severe liver disease", "B": "Renal impairment", "C": "Open wounds or broken skin", "D": "Psoriasis", "E": "None of the above"} | Urea should not be used on open wounds or broken skin. It is a keratolytic agent that can cause irritation and potential systemic absorption when applied to non-intact skin. Urea is generally safe for use in liver disease, renal impairment, and conditions like psoriasis when used as directed. | contraindications_mcq | medium | contraindications | 2025-09-25T17:51:59.454871 | C |
What is the maximum single dose of Succinyl Choline Chloride for intravenous injection in adults? | {"A": "0.5 mg/kg body weight", "B": "1 mg/kg body weight", "C": "2 mg/kg body weight", "D": "500 mg", "E": "None of the above"} | The maximum single dose of Succinyl Choline Chloride for intravenous injection in adults is 500 mg. The initial dose is 1 mg/kg body weight, with maintenance doses of 0.5 to 1 mg/kg body weight every 5 to 10 minutes, but the total dose should not exceed 500 mg. | dose_mcq | medium | dose | 2025-09-25T18:24:25.073167 | D |
What is Streptokinase used to treat? | {"A": "Life-threatening deep-vein thrombosis", "B": "Acute myocardial infarction", "C": "Pulmonary embolism", "D": "Thrombosed arteriovenous shunts", "E": "All of the above"} | Streptokinase is used to treat all of the mentioned conditions. It is indicated for life-threatening deep-vein thrombosis, acute myocardial infarction, pulmonary embolism, and thrombosed arteriovenous shunts. Streptokinase acts as a thrombolytic agent, helping to dissolve blood clots in these serious conditions. | indications_mcq | medium | indications | 2025-09-25T17:42:04.880173 | E |
What should be monitored when using Silver Sulfadiazine? | {"A": "Serum sulfadiazine concentration", "B": "Urine for sulpha crystals", "C": "Renal function", "D": "A and B", "E": "All of the above"} | When using Silver Sulfadiazine, it is important to monitor serum sulfadiazine concentration, check urine for sulpha crystals, and monitor renal function. This is especially important in patients with renal impairment. Additionally, caution is needed in patients with hepatic impairment and G-6-PD deficiency. | precautions_mcq | medium | precautions | 2025-09-25T18:05:11.871866 | E |
What pregnancy category does L- Asparaginase belong to? | {"A": "Category A", "B": "Category B", "C": "Category C", "D": "Category D", "E": "Category X"} | L- Asparaginase belongs to pregnancy category C. This means that either studies in animals have revealed adverse effects on the fetus and there are no controlled studies in women, or studies in women and animals are not available. Drugs in this category should be given only if the potential benefit justifies the potent... | pregnancy_category_mcq | medium | pregnancy_category | 2025-09-25T18:39:04.441915 | C |
Under which schedule is Beclomethasone classified? | {"A": "Schedule H", "B": "Schedule X", "C": "Schedule G", "D": "Schedule K", "E": "None of the above"} | Beclomethasone is classified under Schedule H in the National Formulary of India. Schedule H drugs can only be dispensed on the prescription of a registered medical practitioner and require a special license for sale. | schedule_mcq | medium | schedule | 2025-09-25T18:50:11.429614 | A |
When should Amoxycillin + Clavulanic acid NOT be used? | {"A": "In patients with hypersensitivity to penicillins", "B": "In patients with infectious mononucleosis", "C": "In patients with jaundice", "D": "In patients with mild hypertension", "E": "A, B, and C"} | Amoxycillin + Clavulanic acid is contraindicated in patients with hypersensitivity to penicillins, infectious mononucleosis, and jaundice. These conditions can lead to severe adverse reactions or exacerbation of the existing condition. Mild hypertension is not a contraindication for Amoxycillin + Clavulanic acid use. | contraindications_mcq | medium | contraindications | 2025-09-25T17:53:17.405552 | E |
What is the maximum dose of Flumazenil that can be administered to an adult over one hour? | {"A": "1 mg", "B": "2 mg", "C": "3 mg", "D": "4 mg", "E": "5 mg"} | The maximum dose of Flumazenil that can be administered to an adult over one hour is 3 mg. The recommended dosing is to start with 0.2 mg (2 ml) administered over 30 seconds, intravenously, then repeat 0.3 mg and 0.5 mg at 1-2 minute intervals. The total dose should not exceed 3 mg over one hour. | dose_mcq | medium | dose | 2025-09-25T18:16:44.626117 | C |
What is Amitriptyline used to treat? | {"A": "Moderate to severe depression", "B": "Migraine prophylaxis", "C": "Tension headache", "D": "Enuresis", "E": "All of the above"} | Amitriptyline is used to treat all of the conditions listed: moderate to severe depression, migraine prophylaxis, tension headache, and enuresis. It is a tricyclic antidepressant that has multiple therapeutic applications beyond its primary use in depression. | indications_mcq | medium | indications | 2025-09-25T17:37:51.849988 | E |
What should be monitored when using Zidovudine + Lamivudine + Nevirapine? | {"A": "Liver function", "B": "Blood cell counts", "C": "Skin reactions", "D": "All of the above", "E": "None of the above"} | When using Zidovudine + Lamivudine + Nevirapine, it is important to monitor liver function, blood cell counts, and skin reactions. Liver function tests are necessary due to the potential for hepatotoxicity, especially with Nevirapine. Blood cell counts should be monitored because Zidovudine can cause bone marrow suppre... | precautions_mcq | medium | precautions | 2025-09-25T18:14:14.521913 | D |
What pregnancy category does Tetracaine belong to? | {"A": "Category A", "B": "Category B", "C": "Category C", "D": "Category D", "E": "Category X"} | Tetracaine belongs to pregnancy category C. This means that either studies in animals have revealed adverse effects on the fetus (teratogenic or embryocidal or other) and there are no controlled studies in women, or studies in women and animals are not available. Drugs in this category should be given only if the poten... | pregnancy_safety_mcq | medium | pregnancy_category | 2025-09-25T18:39:49.886084 | C |
Under which schedule is Ipratropium classified? | {"A": "Schedule H", "B": "Schedule X", "C": "Schedule G", "D": "Schedule K", "E": "None of the above"} | Ipratropium is not classified under any controlled substance schedule in India. It is available as a prescription medication but is not subject to the stricter controls associated with scheduled drugs. | schedule_mcq | medium | schedule | 2025-09-25T18:48:59.536199 | E |
In which condition should Acetazolamide be avoided? | {"A": "Hyponatraemia", "B": "Chronic open-angle glaucoma", "C": "Hyperchloraemic acidosis", "D": "Renal impairment", "E": "All of the above"} | Acetazolamide should be avoided in all the mentioned conditions. It is contraindicated in hyponatraemia, hyperchloraemic acidosis, and renal impairment. While not listed in the given contraindications, chronic open-angle glaucoma is not a contraindication; however, chronic angle-closure glaucoma is contraindicated as A... | contraindications_mcq | medium | contraindications | 2025-09-25T17:43:12.355624 | E |
What is the recommended daily dose of Ascorbic Acid (Vitamin C) for the treatment of scurvy in adults? | {"A": "25 to 75 mg", "B": "100 to 250 mg", "C": "0.5 to 1.5 g", "D": "2 to 3 g", "E": "5 to 10 g"} | For the treatment of scurvy in adults, the recommended daily dose of Ascorbic Acid (Vitamin C) is 0.5 to 1.5 g/day. This higher dose is necessary to rapidly replenish vitamin C levels and reverse the symptoms of scurvy. The lower dose of 25 to 75 mg daily is used for prophylaxis of scurvy, not treatment. | dose_mcq | medium | dose | 2025-09-25T18:32:00.324939 | C |
What is Theophylline used to treat? | {"A": "Chronic asthma", "B": "Nocturnal asthma", "C": "Acute severe asthma", "D": "Apnoea of prematurity", "E": "All of the above"} | Theophylline is used to treat chronic asthma (including nocturnal asthma), acute severe asthma, and apnoea of prematurity. It is a bronchodilator that helps to relax and open air passages in the lungs, making it easier to breathe. | indications_mcq | medium | indications | 2025-09-25T17:30:58.375209 | E |
What should be monitored when using Esmolol? | {"A": "Blood pressure", "B": "Heart rate", "C": "ECG", "D": "Renal function", "E": "All of the above"} | When using Esmolol, it is important to monitor blood pressure, heart rate, ECG, and renal function. Esmolol is a beta-blocker that can affect cardiovascular parameters and kidney function. Regular monitoring of these parameters helps ensure patient safety and appropriate dosing. | precautions_mcq | medium | precautions | 2025-09-25T18:10:29.883233 | E |
Is Glucose + Sodium Chloride safe during pregnancy? | {"A": "Completely safe (Category A)", "B": "Generally safe (Category B)", "C": "Use with caution (Category C)", "D": "Risk outweighs benefits (Category D)", "E": "Not enough information available"} | There is not enough information available in the National Formulary of India to definitively categorize Glucose + Sodium Chloride for use during pregnancy. Without specific pregnancy category information, healthcare providers must assess the potential benefits and risks on a case-by-case basis. | pregnancy_safety_mcq | medium | pregnancy_category | 2025-09-25T18:41:45.175429 | E |
Under which schedule is Bromocriptine classified? | {"A": "Schedule H", "B": "Schedule X", "C": "Schedule G", "D": "Schedule K", "E": "None of the above"} | Bromocriptine is classified under Schedule H in the National Formulary of India. Schedule H drugs can only be dispensed on the prescription of a registered medical practitioner and cannot be sold over the counter. | schedule_mcq | medium | schedule | 2025-09-25T18:59:51.911673 | A |
When should Gamma Benzene Hexachloride NOT be used? | {"A": "In patients with seizures", "B": "In patients with skin inflammation", "C": "In pregnant women", "D": "In lactating mothers", "E": "All of the above"} | Gamma Benzene Hexachloride is contraindicated in patients with seizures, skin inflammation, broken skin, premature infants, during lactation, and in pregnancy. It should not be used in these conditions due to potential risks and safety concerns. | contraindications_mcq | medium | contraindications | 2025-09-25T17:49:27.706736 | E |
What is the maximum daily dose of Ceftriaxone for an adult with urinary tract infection? | {"A": "2g", "B": "3g", "C": "4g", "D": "6g", "E": "None of the above"} | For adults with urinary tract infection, the maximum daily dose of Ceftriaxone is 4g. This is given as 4g initially once daily for 10 days or up to 72 hours after fever disappears. | dose_mcq | medium | dose | 2025-09-25T18:24:03.010811 | C |
What is Nalidixic Acid used to treat? | {"A": "Urinary-tract infections", "B": "Shigellosis", "C": "Pneumonia", "D": "Malaria", "E": "A and B"} | Nalidixic Acid is used to treat urinary-tract infections and shigellosis. It is not indicated for pneumonia or malaria. | indications_mcq | medium | indications | 2025-09-25T17:38:37.241277 | E |
What should be monitored when using Water for Injection? | {"A": "Sterility", "B": "Pyrogen content", "C": "Particulate matter", "D": "pH level", "E": "All of the above"} | When using Water for Injection, it is crucial to monitor all of the mentioned factors. Sterility is essential to prevent microbial contamination. Pyrogen content must be checked to avoid potential fever reactions. Particulate matter should be absent to ensure safety. The pH level should be monitored to maintain the app... | precautions_mcq | medium | precautions | 2025-09-25T18:13:55.740846 | E |
What pregnancy category does Lithium Carbonate belong to? | {"A": "Category A", "B": "Category B", "C": "Category C", "D": "Category D", "E": "Category X"} | Lithium Carbonate belongs to pregnancy category D. This means there is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk (e.g., if the drug is needed in a life-threatening situation or for a serious disease for which safer drugs cannot be used or are i... | pregnancy_category_mcq | medium | pregnancy_category | 2025-09-25T18:43:33.544264 | D |
Eka NFI MCQA
A multiple-choice question answering dataset for evaluating knowledge of drug pharmacology as defined in the National Formulary of India (NFI) 2011 — covering indications, contraindications, dosing, precautions, pregnancy safety, and drug schedules.
Dataset Description
This dataset contains 925 questions derived from the National Formulary of India (NFI), 2011, a government-published reference for drug information in the Indian healthcare context. Questions span 6 pharmacological categories and test both factual recall and clinical reasoning.
Use Cases
- Evaluate medical LLMs on drug knowledge grounded in the Indian national formulary
- Benchmark pharmacology understanding across indications, contraindications, dosing, and safety
- Test drug schedule and pregnancy category classification per Indian regulatory standards
Dataset Structure
| Column | Type | Description |
|---|---|---|
question |
string | The MCQ question stem |
options |
string | JSON-encoded dict of answer options (keys: A–E) |
answer |
string | Correct answer letter (A–E) |
explanation |
string | Explanation of the correct answer |
question_type |
string | Fine-grained question type (e.g., dose_mcq, contraindications_multi_select) |
category |
string | Pharmacological category (see below) |
difficulty |
string | Difficulty level (medium or hard) |
generation_timestamp |
string | ISO timestamp of question generation |
Categories
| Category | Questions | Description |
|---|---|---|
contraindications |
166 | Conditions or patient profiles where a drug must not be used |
precautions |
166 | Situations requiring caution or dose modification |
pregnancy_category |
166 | Drug safety classification during pregnancy |
dose |
157 | Dosing regimens, routes, and frequencies |
schedule |
148 | Drug schedule classification under Indian law |
indications |
122 | Approved therapeutic uses of the drug |
Question Types
Each category includes both single-correct (_mcq) and multi-select (_multi_select) formats:
| Question Type | Count |
|---|---|
contraindications_mcq |
164 |
precautions_mcq |
124 |
dose_mcq |
156 |
schedule_mcq |
148 |
pregnancy_category_mcq |
148 |
indications_mcq |
121 |
pregnancy_safety_mcq |
18 |
precautions_multi_select |
42 |
contraindications_multi_select |
2 |
dose_multi_select |
1 |
indications_multi_select |
1 |
Difficulty Distribution
| Difficulty | Count |
|---|---|
medium |
911 |
hard |
14 |
How It Was Made
- Source extraction — The NFI 2011 PDF was parsed to extract structured drug annotations (indications, contraindications, dosing, precautions, pregnancy categories, schedules).
- Human review — Extracted annotations were reviewed and validated by humans for accuracy and completeness.
- LLM-generated MCQA — Questions and distractor options were generated by an LLM using the validated annotations as ground truth.
- Human review — Generated questions were reviewed again to ensure clinical correctness and remove low-quality items.
Usage
With KARMA Evaluation Framework
karma eval \
--model "Qwen/Qwen3-0.6B" \
--datasets "ekacare/Eka_NFI_MCQA" \
--format table
Direct Loading
from datasets import load_dataset
import json
ds = load_dataset("ekacare/Eka_NFI_MCQA", split="test")
example = ds[0]
print(example["question"])
print(json.loads(example["options"])) # {"A": "...", "B": "...", ...}
print("Answer:", example["answer"])
print("Explanation:", example["explanation"])
Evaluation
For single-correct questions (_mcq types), use exact match on the predicted answer letter (A–E).
For multi-select questions (_multi_select types), the correct answer may be a combination letter like "A, C" — parse accordingly.
def score(prediction, ground_truth):
return int(prediction.strip().upper() == ground_truth.strip().upper())
Citation
If you use this dataset, please cite:
@dataset{eka_nfi_mcqa_2025,
title={Eka NFI MCQA},
author={Eka.Care},
year={2025},
publisher={HuggingFace},
url={https://huggingface.co/datasets/ekacare/Eka_NFI_MCQA}
}
License
This dataset is released under CC-BY-NC-4.0. The source material is the National Formulary of India, 2011, published by the Ministry of Health and Family Welfare, Government of India.
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