query listlengths 1 212 | applicant_patent_id stringlengths 11 15 | cited_patent_id stringlengths 9 16 | positive listlengths 1 671 | hard_negatives listlengths 5 30 | 102rejection stringlengths 116 79.2k |
|---|---|---|---|---|---|
[
"1. A method of reducing the number of intratumoral T regulatory cells in a subject in need thereof comprising administering to the subject an effective amount of a CD36 inhibitor or a PPARβ inhibitor.",
"3. The method of claim 1, wherein the intratumoral T regulatory cells are CD4+ cells.",
"4. A method of inc... | US20220049010A1 | WO2017055411A1 | [
"1. A blocker of activity and/or expression of CD36 for use in the treatment of cancer in a mammal, wherein the cancer is oral squamous cell cancer (OSCC).",
"2. A blocker of activity and/or expression of CD36 for use according to claim 1 , wherein the OSCC has generated at least one metastasis.",
"3. A blocker... | [
[
"1. A molecule or molecule complex comprising a TLR9 binding region capable of binding to TLR9, a CD32 binding region capable of binding to CD32, and at least one epitope of at least one antigen.",
"2. A molecule or molecule complex according to claim 1, characterized in that the epitope is a T cell epito... | the rejection of claims 21, 30 and 33 under 35 u.s.c. 102(a)(1) as being anticipated by aznar et al., (from ids, wo 2017055411; published 6/4/2017), as evidenced by wang et al., (nat. immunol., 2020, 21(3)), is withdrawn. specifically, applicants amended claim 21 such that the aznar reference no longer anticipates each... |
["1. A system, comprising:\na processor arrangement communicatively coupled to a data storage arrang(...TRUNCATED) | US20230027455A1 | US20190321553A1 | ["1. A method of automatically adjusting parameters of an insulin delivery controller of a dual-mode(...TRUNCATED) | [["1. A system, comprising:\na wearable monitoring apparatus including:\na housing adapted to be wor(...TRUNCATED) | "in the event the determination of the status of the application as subject to aia 35 u.s.c. 102 and(...TRUNCATED) |
["1. A system comprising:\na memory; and\na processor in communication with the memory, the processo(...TRUNCATED) | US20230412403A1 | US20190372765A1 | ["1. A system for providing to a designated third party system access to a secret, the system compri(...TRUNCATED) | [["1. An apparatus, comprising:\na memory storing instructions; and\nat least one processor coupled (...TRUNCATED) | "in the event the determination of the status of the application as subject to aia 35 u.s.c. 102 and(...TRUNCATED) |
["1. A suture anchor comprising:\na cylindrical body having an entry tip at a distal end portion and(...TRUNCATED) | US20210100545A1 | US20090076545A1 | ["1. A method for anchoring suture to bone, comprising:\ncoupling a suture to a suture anchor such t(...TRUNCATED) | [["1. A meni seal tissue repair device, comprising:\nan outer tube, the outer tube comprising an ope(...TRUNCATED) | "in the event the determination of the status of the application as subject to aia 35 u.s.c. 102 and(...TRUNCATED) |
["1. A method comprising:\n(i) contacting a population of polypeptides with a barcode component to p(...TRUNCATED) | US20210147474A1 | WO2019089836A1 | ["1. A method for analyzing a macromolecule, comprising the steps of:","(a) providing a macromolecul(...TRUNCATED) | [["1. A compound having the formula:\nwherein n is an integer from 1 to 6, and R1, R2, R3 and R4 are(...TRUNCATED) | "the following is a quotation of the appropriate paragraphs of 35 u.s.c. 102 that form the basis for(...TRUNCATED) |
["1. A cooling treatment system for applying cooling therapy to a desired tissue region of a patient(...TRUNCATED) | US20220346852A1 | US20100036295A1 | ["1. A method for treating tissue, comprising:\nsimultaneously compressing sub-volumes of the subjec(...TRUNCATED) | [["1. A system for clearing a sinus ostium of a patient comprising:\na catheter assembly configured (...TRUNCATED) | "the following is a quotation of the appropriate paragraphs of 35 u.s.c. 102 that form the basis for(...TRUNCATED) |
["1. A solar cell, comprising:\na silicon substrate having a first polarity or a second polarity, wh(...TRUNCATED) | US20230327030A1 | US20140224307A1 | ["1. A photovoltaic device, comprising:\na crystalline substrate having a first dopant conductivity;(...TRUNCATED) | [["1. A solar cell, comprising:\na substrate having a front surface and a back surface opposite to t(...TRUNCATED) | "in the event the determination of the status of the application as subject to aia 35 u.s.c. 102 and(...TRUNCATED) |
["1. A firearm suppressor comprising:\na plurality of fluid redirectors, each of the plurality of fl(...TRUNCATED) | US20210180902A1 | RU2397422C1 | ["1. Vortex silencer of a shot, comprising a separator body made in the form of a hollow cylinder wi(...TRUNCATED) | [["1. An apparatus for suppressing the blast and flash produced as a projectile is expelled by gases(...TRUNCATED) | "the following is a quotation of the appropriate paragraphs of 35 u.s.c. 102 that form the basis for(...TRUNCATED) |
["1. An electric motor comprising:\na stator including a shell body substantially-enclosing cylindri(...TRUNCATED) | US20200366140A1 | JP6866803B2 | ["3. Claim 3 or claim 4 is characterized in that the data generation unit generates a conversion par(...TRUNCATED) | [["1. A hydraulically-driven double-acting mud pump, comprising power motors, pressure oil pumps, a (...TRUNCATED) | "the following is a quotation of the appropriate paragraphs of 35 u.s.c. 102 that form the basis for(...TRUNCATED) |
["1. A method of treating pulmonary hypertension, comprising administering to a subject in need ther(...TRUNCATED) | US20210154238A1 | WO2015179227A1 | ["1. An isolated exosome, wherein","(i) the isolated exosome comprises one or more markers selected (...TRUNCATED) | [["1. A method of augmenting autologous fat transfer to a subject, comprising:\nremoving a first por(...TRUNCATED) | "the following is a quotation of the appropriate paragraphs of 35 u.s.c. 102 that form the basis for(...TRUNCATED) |
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