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Introduction
Human malaria is caused by four species of the parasitic protozoan genus Plasmodium. Of these four species, Plasmodium falciparum is responsible for the vast majority of the 300–500 million episodes of malaria worldwide and accounts for 0.7–2.7 million annual deaths. In many endemic countries, malaria is r... | 12929205 | PMC176545 | CC BY | 2021-01-05 08:21:03 | no | PLoS Biol. 2003 Oct 18; 1(1):e5 |
Introduction
Elephants have a very limited distribution in Borneo, being restricted to approximately 5% of the island in the extreme northeast (Figure 1). There are no historical records of elephants outside of this range. Fossil evidence for the prehistoric presence of elephants on Borneo is limited to a single specim... | 12929206 | PMC176546 | CC BY | 2021-01-05 08:21:06 | no | PLoS Biol. 2003 Oct 18; 1(1):e6 |
A new study settles a long-standing dispute about the genesis of an endangered species. With scant fossil evidence supporting a prehistoric presence, scientists could not say for sure where Borneo's elephants came from. Did they descend from ancient prototypes of the Pleistocene era or from modern relatives introduced ... | 0 | PMC176547 | CC BY | 2021-01-05 08:21:06 | no | PLoS Biol. 2003 Oct 18; 1(1):e7 |
Every year, malaria kills as many as 2.5 million people. Of these deaths, 90% occur in sub-Saharan Africa, and most are children. While four species of the single-celled organism Plasmodium cause malaria, Plasmodium falciparum is the deadliest. Harbored in mosquito saliva, the parasite infects its human host as the mos... | 0 | PMC176548 | CC BY | 2021-01-05 08:21:04 | no | PLoS Biol. 2003 Oct 18; 1(1):e11 |
Introduction
Circadian rhythms of diverse organisms are based on similar intracellular molecular feedback loops (Dunlap 1999; Allada et al. 2001; Panda et al. 2002). Based on this view, it is believed that one or a small number of clock cells are sufficient for self-sustained rhythms (Dunlap 1999). This is despite the ... | 12975658 | PMC193604 | CC BY | 2021-01-05 08:21:03 | no | PLoS Biol. 2003 Oct 15; 1(1):e13 |
Introduction
The availability of complete sequences of genomes for clusters of related organisms presents the first opportunity to reconstruct events of genomic evolution. By comparing related genomes and inferring ancestral ones, we can identify events, such as specific chromosomal rearrangements, gene acquisitions, d... | 12975657 | PMC193605 | CC BY | 2021-01-05 08:21:03 | no | PLoS Biol. 2003 Oct 15; 1(1):e19 |
How do people subjected to the endless dark days of winter in the far northern latitudes maintain normal daily rhythms? Though many might feel like hibernating, a highly regulated internal system keeps such impractical yearnings in check. From fruit flies to humans, nearly every living organism depends on an internal c... | 0 | PMC193606 | CC BY | 2021-01-05 08:21:04 | no | PLoS Biol. 2003 Oct 15; 1(1):e23 |
Bacteria are an indiscriminate lot. While most organisms tend to pass their genes on to the next generation of their species, bacteria often exchange genetic material with totally unrelated species. That is why skeptics doubted that bacteria researchers could ever hope to map a reliable history of cell lineages in bact... | 0 | PMC193607 | CC BY | 2021-01-05 08:21:04 | no | PLoS Biol. 2003 Oct 15; 1(1):e31 |
"pmcBackground\n\nSmall GTPases of the ADP-ribosylation factor (ARF) family play a major role in mem(...TRUNCATED) | 12969509 | PMC212319 | CC BY | 2022-01-04 23:15:02 | no | BMC Cell Biol. 2003 Sep 11; 4:13 |
"Introduction\nDuring B- and T-lymphocyte development, the immunoglobulin (Ig) and T-cell receptor ((...TRUNCATED) | 14551903 | PMC212687 | CC BY | 2021-01-05 08:21:03 | no | PLoS Biol. 2003 Oct 13; 1(1):e1 |
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