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Development is often strongly regulated by interactions among close relatives , but the underlying molecular mechanisms are largely unknown . In eusocial insects , interactions between caregiving worker nurses and larvae regulate ... | Social interactions are fundamental to all forms of life , from single-celled bacteria to complex plants and animals . Despite their obvious importance , little is known about the molecular causes and consequences of social interactions . In this paper , we study the molecular basis of nurse-larva social interactions t... |
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Crimean-Congo hemorrhagic fever virus ( CCHFV ) is a zoonotic agent that causes severe , life-threatening disease , with a case fatality rate of 10–50% . It is the most widespread tick-borne virus in the world , with cases reporte... | Crimean-Congo hemorrhagic fever ( CCHF ) is an acute , tick-borne disease with a case fatality rate of 10–30% . It is geographically the most widespread tick-borne disease in the world . In recent years there has been an increase of the disease incidence in several countries , mainly in the countries of the Balkan . Th... |
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Spermatogenesis is a dynamic process that is regulated by adhesive interactions between germ and Sertoli cells . Germ cells express the Junctional Adhesion Molecule-C ( JAM-C , encoded by Jam3 ) , which localizes to germ/Sertoli c... | Spermatogenesis defects are a common cause of male sterility . Spermatogenesis occurs in the seminiferous tubules of the testes and involves adhesive interactions between developing germ cells and Sertoli cells . Knock-out mouse models identified several adhesion molecules that are critically involved in spermatogenesi... |
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Screening of herbal remedies for Cl− channel inhibition identified Krisanaklan , a herbal extract used in Thailand for treatment of diarrhea , as an effective antidiarrheal in mouse models of secretory diarrheas with inhibition ac... | Secretory diarrhea is a major health challenge in developing countries . Causative agents include bacteria , as in cholera , and viruses , as in childhood rotaviral diarrhea . Though oral rehydration solution ( ORS ) has reduced mortality from diarrhea four-fold in the last three decades , its efficacy is limited , par... |
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Circadian clocks are endogenous time-keeping systems that temporally organize biological processes . Gating of cell cycle events by a circadian clock is a universal observation that is currently considered a mechanism serving to p... | Circadian clock and cell cycle are two important biological processes that are essential for nearly all eukaryotes . The circadian clock governs day and night 24 h periodic molecular processes and physiological behaviors , while cell cycle controls cell division process . It has been widely observed that cell division ... |
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