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|---|---|---|---|---|---|---|---|---|---|---|---|
CN=C(NC#N)NCCSCc1nc[nH]c1C | cimetidine | 0,0000007 | null | 10.1021/js9802594 | null | Permeability of cornea, sclera, and conjunctiva: a literature analysis for drug delivery to the eye | American Geophysical Union (AGU) | 1,998 | 0 | 2 | table 1 |
COC(=O)C1C(OC(=O)c2ccccc2)CC2CCC1N2C | cocaine | 0,0000061 | null | 10.1021/js9802594 | null | Permeability of cornea, sclera, and conjunctiva: a literature analysis for drug delivery to the eye | American Geophysical Union (AGU) | 1,998 | 0 | 2 | table 1 |
CC12CCC(=O)C=C1CCC1C2CCC2(C)C1CCC2(O)C(=O)CO | cortexolone | 0,00003 | null | 10.1021/js9802594 | null | Permeability of cornea, sclera, and conjunctiva: a literature analysis for drug delivery to the eye | American Geophysical Union (AGU) | 1,998 | 0 | 2 | table 1 |
COC(=O)C1C(O)CCC2CN3CCc4c([nH]c5ccccc45)C3CC21 | corynanthine | 0,000011 | null | 10.1021/js9802594 | null | Permeability of cornea, sclera, and conjunctiva: a literature analysis for drug delivery to the eye | American Geophysical Union (AGU) | 1,998 | 0 | 2 | table 1 |
CC=CCC(C)C(O)C1C(=O)NC(CC)C(=O)N(C)CC(=O)N(C)C(CC(C)C)C(=O)NC(C(C)C)C(=O)N(C)C(CC(C)C)C(=O)NC(C)C(=O)NC(C)C(=O)N(C)C(CC(C)C)C(=O)N(C)C(CC(C)C)C(=O)N(C)C(C(C)C)C(=O)N1C | cyclosporin | 0,000011 | null | 10.1021/js9802594 | null | Permeability of cornea, sclera, and conjunctiva: a literature analysis for drug delivery to the eye | American Geophysical Union (AGU) | 1,998 | 0 | 2 | table 1 |
CC12CCC(=O)C=C1CCC1C2CCC2(C)C(C(=O)CO)CCC12 | deoxycorticosterone | 0,00004 | null | 10.1021/js9802594 | null | Permeability of cornea, sclera, and conjunctiva: a literature analysis for drug delivery to the eye | American Geophysical Union (AGU) | 1,998 | 0 | 2 | table 1 |
O=CCC(O)C(O)C(O)CO | 2-deoxyglucose | 0,0000074 | null | 10.1021/js9802594 | null | Permeability of cornea, sclera, and conjunctiva: a literature analysis for drug delivery to the eye | American Geophysical Union (AGU) | 1,998 | 0 | 2 | table 1 |
OC[C@H]1O[C@H](OC2CC2)C[C@@H](O)[C@@H]1O | 2-deoxyglucose der.1i | 0,0000022 | null | 10.1021/js9802594 | null | Permeability of cornea, sclera, and conjunctiva: a literature analysis for drug delivery to the eye | American Geophysical Union (AGU) | 1,998 | 0 | 2 | table 1 |
CCOC1CC(O)C(O)C(CO)O1 | 2-deoxyglucose der.2i | 0,0000029 | null | 10.1021/js9802594 | null | Permeability of cornea, sclera, and conjunctiva: a literature analysis for drug delivery to the eye | American Geophysical Union (AGU) | 1,998 | 0 | 2 | table 1 |
CC(C)OC1CC(O)C(O)C(CO)O1 | 2-deoxyglucose der.3i | 0,0000018 | null | 10.1021/js9802594 | null | Permeability of cornea, sclera, and conjunctiva: a literature analysis for drug delivery to the eye | American Geophysical Union (AGU) | 1,998 | 0 | 2 | table 1 |
COC1CC(O)C(O)C(CO)O1 | 2-deoxyglucose der.4i | 0,0000046 | null | 10.1021/js9802594 | null | Permeability of cornea, sclera, and conjunctiva: a literature analysis for drug delivery to the eye | American Geophysical Union (AGU) | 1,998 | 0 | 2 | table 1 |
CC1CC2C3CCC4=CC(=O)C=CC4(C)C3(F)C(O)CC2(C)C1(O)C(=O)CO | dexamethasone | 0,000005 | null | 10.1021/js9802594 | null | Permeability of cornea, sclera, and conjunctiva: a literature analysis for drug delivery to the eye | American Geophysical Union (AGU) | 1,998 | 0 | 2 | table 1 |
CC(=O)OCC(=O)C1(O)C(C)CC2C3CCC4=CC(=O)C=CC4(C)C3(F)C(O)CC21C | Dexamethasone acetate | 0,000037 | null | 10.1021/js9802594 | null | Permeability of cornea, sclera, and conjunctiva: a literature analysis for drug delivery to the eye | American Geophysical Union (AGU) | 1,998 | 0 | 2 | table 1 |
COc1ccc(OC)c(N)c1 | 2,5-dimethoxyaniline | 0,000033 | null | 10.1021/js9802594 | null | Permeability of cornea, sclera, and conjunctiva: a literature analysis for drug delivery to the eye | American Geophysical Union (AGU) | 1,998 | 0 | 2 | table 1 |
O=C(O)CN(CCN(CC(=O)O)CC(=O)O)CC(=O)O | Edetic acid (EDTA) | 0,0000021 | null | 10.1021/js9802594 | null | Permeability of cornea, sclera, and conjunctiva: a literature analysis for drug delivery to the eye | American Geophysical Union (AGU) | 1,998 | 0 | 2 | table 1 |
NCCO | ethanolamine | 0,0000005 | null | 10.1021/js9802594 | null | Permeability of cornea, sclera, and conjunctiva: a literature analysis for drug delivery to the eye | American Geophysical Union (AGU) | 1,998 | 0 | 2 | table 1 |
CCOc1ccc2nc(S(N)(=O)=O)sc2c1 | ethoxzolamide | 0,000044 | null | 10.1021/js9802594 | null | Permeability of cornea, sclera, and conjunctiva: a literature analysis for drug delivery to the eye | American Geophysical Union (AGU) | 1,998 | 0 | 2 | table 1 |
NS(=O)(=O)c1nc2ccccc2s1 | Ethoxzolamide der.1j | 0,000036 | null | 10.1021/js9802594 | null | Permeability of cornea, sclera, and conjunctiva: a literature analysis for drug delivery to the eye | American Geophysical Union (AGU) | 1,998 | 0 | 2 | table 1 |
NS(=O)(=O)c1nc2ccc(O)cc2s1 | Ethoxzolamide der.2j | 0,0000056 | null | 10.1021/js9802594 | null | Permeability of cornea, sclera, and conjunctiva: a literature analysis for drug delivery to the eye | American Geophysical Union (AGU) | 1,998 | 0 | 2 | table 1 |
NS(=O)(=O)c1nc2ccc(Cl)cc2s1 | Ethoxzolamide der.3j | 0,000043 | null | 10.1021/js9802594 | null | Permeability of cornea, sclera, and conjunctiva: a literature analysis for drug delivery to the eye | American Geophysical Union (AGU) | 1,998 | 0 | 2 | table 1 |
NS(=O)(=O)c1nc2c(Cl)cc(Cl)cc2s1 | Ethoxzolamide der.4j | 0,000039 | null | 10.1021/js9802594 | null | Permeability of cornea, sclera, and conjunctiva: a literature analysis for drug delivery to the eye | American Geophysical Union (AGU) | 1,998 | 0 | 2 | table 1 |
Nc1ccc2nc(S(N)(=O)=O)sc2c1 | Ethoxzolamide der.5j | 0,0000067 | null | 10.1021/js9802594 | null | Permeability of cornea, sclera, and conjunctiva: a literature analysis for drug delivery to the eye | American Geophysical Union (AGU) | 1,998 | 0 | 2 | table 1 |
NS(=O)(=O)c1nc2ccc([N+](=O)[O-])cc2s1 | Ethoxzolamide der.6j | 0,0000066 | null | 10.1021/js9802594 | null | Permeability of cornea, sclera, and conjunctiva: a literature analysis for drug delivery to the eye | American Geophysical Union (AGU) | 1,998 | 0 | 2 | table 1 |
NS(=O)(=O)c1nc2ccc(OCCO)cc2s1 | Ethoxzolamide der.7j | 0,0000015 | null | 10.1021/js9802594 | null | Permeability of cornea, sclera, and conjunctiva: a literature analysis for drug delivery to the eye | American Geophysical Union (AGU) | 1,998 | 0 | 2 | table 1 |
NS(=O)(=O)c1nc2ccc(OCc3ccccc3)cc2s1 | Ethoxzolamide der.8j | 0,000047 | null | 10.1021/js9802594 | null | Permeability of cornea, sclera, and conjunctiva: a literature analysis for drug delivery to the eye | American Geophysical Union (AGU) | 1,998 | 0 | 2 | table 1 |
CC(=O)Nc1ccc2nc(S(N)(=O)=O)sc2c1 | Ethoxzolamide der.9j | 0,0000047 | null | 10.1021/js9802594 | null | Permeability of cornea, sclera, and conjunctiva: a literature analysis for drug delivery to the eye | American Geophysical Union (AGU) | 1,998 | 0 | 2 | table 1 |
NS(=O)(=O)c1nn2c(=Nc3cccc(F)c3)snc2s1 | Thiadiazole der.7n | 0,0000064 | null | 10.1021/js9802594 | null | Permeability of cornea, sclera, and conjunctiva: a literature analysis for drug delivery to the eye | American Geophysical Union (AGU) | 1,998 | 0 | 4 | table 1 |
NS(=O)(=O)c1nn2c(=Nc3ccc(F)cc3)snc2s1 | Thiadiazole der.8n | 0,0000041 | null | 10.1021/js9802594 | null | Permeability of cornea, sclera, and conjunctiva: a literature analysis for drug delivery to the eye | American Geophysical Union (AGU) | 1,998 | 0 | 4 | table 1 |
CN(C)c1ccc(N=c2snc3sc(S(N)(=O)=O)nn23)cc1 | Thiadiazole der.9n | 0,0000058 | null | 10.1021/js9802594 | null | Permeability of cornea, sclera, and conjunctiva: a literature analysis for drug delivery to the eye | American Geophysical Union (AGU) | 1,998 | 0 | 4 | table 1 |
CC(C)(C)NCC(O)COc1nsnc1N1CCOCC1 | timolol | 0,000012 | null | 10.1021/js9802594 | null | Permeability of cornea, sclera, and conjunctiva: a literature analysis for drug delivery to the eye | American Geophysical Union (AGU) | 1,998 | 0 | 4 | table 1 |
NCC1OC(OC2C(N)CC(N)C(OC3OC(CO)C(O)C(N)C3O)C2O)C(N)CC1O | tobramycin | 0,00000052 | null | 10.1021/js9802594 | null | Permeability of cornea, sclera, and conjunctiva: a literature analysis for drug delivery to the eye | American Geophysical Union (AGU) | 1,998 | 0 | 4 | table 1 |
CC1(C)OC2CC3C4CCC5=CC(=O)C=CC5(C)C4(F)C(O)CC3(C)C2(C(=O)CO)O1 | triamcinolone acetonide | 0,000012 | null | 10.1021/js9802594 | null | Permeability of cornea, sclera, and conjunctiva: a literature analysis for drug delivery to the eye | American Geophysical Union (AGU) | 1,998 | 0 | 4 | table 1 |
Cn1nc(S(N)(=O)=O)sc1=NC(=O)C(Cl)(Cl)Cl | trichlormethazolamide | 0,0000065 | null | 10.1021/js9802594 | null | Permeability of cornea, sclera, and conjunctiva: a literature analysis for drug delivery to the eye | American Geophysical Union (AGU) | 1,998 | 0 | 4 | table 1 |
Cn1nc(S(N)(=O)=O)sc1=NC(=O)C(F)(F)F | trifluormethazolamide | 0,0000039 | null | 10.1021/js9802594 | null | Permeability of cornea, sclera, and conjunctiva: a literature analysis for drug delivery to the eye | American Geophysical Union (AGU) | 1,998 | 0 | 4 | table 1 |
NS(=O)(=O)c1nc2ccccc2s1 | 2-benzothiazole-sulfonamide | 0,000036 | null | 10.1007/s11095-010-0132-8 | null | Prediction of the Corneal Permeability of Drug-Like Compounds | Springer Science and Business Media LLC | 2,010 | 0 | 3 | table 1 |
CCn1nc(C(=O)O)c(=O)c2cc3c(cc21)OCO3 | cinoxacin | 0,0000015 | null | 10.1007/s11095-010-0132-8 | null | Prediction of the Corneal Permeability of Drug-Like Compounds | Springer Science and Business Media LLC | 2,010 | 0 | 4 | table 1 |
CCn1cc(C(=O)O)c(=O)c2ccc(C)nc21 | Nalidixic acid | 0,000017 | null | 10.1007/s11095-010-0132-8 | null | Prediction of the Corneal Permeability of Drug-Like Compounds | Springer Science and Business Media LLC | 2,010 | 0 | 4 | table 1 |
CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 | enoxacin | 0,0000017 | null | 10.1007/s11095-010-0132-8 | null | Prediction of the Corneal Permeability of Drug-Like Compounds | Springer Science and Business Media LLC | 2,010 | 0 | 4 | table 1 |
CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 | norfloxacin | 0,0000014 | null | 10.1007/s11095-010-0132-8 | null | Prediction of the Corneal Permeability of Drug-Like Compounds | Springer Science and Business Media LLC | 2,010 | 0 | 4 | table 1 |
CC1COc2c(N3CCN(C)CC3)c(F)cc3c(=O)c(C(=O)O)cn1c23 | ofloxacin | 0,0000019 | null | 10.1007/s11095-010-0132-8 | null | Prediction of the Corneal Permeability of Drug-Like Compounds | Springer Science and Business Media LLC | 2,010 | 0 | 4 | table 1 |
O=C(O)c1cn(C2CC2)c2cc(N3CCNCC3)c(F)cc2c1=O | ciprofloxacin | 0,0000013 | null | 10.1007/s11095-010-0132-8 | null | Prediction of the Corneal Permeability of Drug-Like Compounds | Springer Science and Business Media LLC | 2,010 | 0 | 4 | table 1 |
CC1(C)SC2C(NC(=O)C(N)c3ccccc3)C(=O)N2C1C(=O)O | Ampicillin | 0,00000019 | null | 10.1016/j.ejps.2018.03.034 | null | Corneal and conjunctival drug permeability: Systematic comparison and pharmacokinetic impact in the eye | Elsevier BV | 2,018 | 0 | 3 | table 1 |
CN1C2CCC1CC(OC(=O)C(CO)c1ccccc1)C2 | Atropine | 0,00000056 | null | 10.1016/j.ejps.2018.03.034 | null | Corneal and conjunctival drug permeability: Systematic comparison and pharmacokinetic impact in the eye | Elsevier BV | 2,018 | 0 | 3 | table 1 |
CC1C(NC(=O)C(=NOC(C)(C)C(=O)O)c2csc(N)n2)C(=O)N1S(=O)(=O)O | Aztreonam | 0,000000102 | null | 10.1016/j.ejps.2018.03.034 | null | Corneal and conjunctival drug permeability: Systematic comparison and pharmacokinetic impact in the eye | Elsevier BV | 2,018 | 0 | 3 | table 1 |
CCNC1CN(CCCOC)S(=O)(=O)c2sc(S(N)(=O)=O)cc21 | Brinzolamide | 0,000000136 | null | 10.1016/j.ejps.2018.03.034 | null | Corneal and conjunctival drug permeability: Systematic comparison and pharmacokinetic impact in the eye | Elsevier BV | 2,018 | 0 | 3 | table 1 |
Nc1c(CC(=O)O)cccc1C(=O)c1ccc(Br)cc1 | Bromfenac | 0,000000399 | null | 10.1016/j.ejps.2018.03.034 | null | Corneal and conjunctival drug permeability: Systematic comparison and pharmacokinetic impact in the eye | Elsevier BV | 2,018 | 0 | 3 | table 1 |
CC(C)(C)NCC(O)COc1cccc2c1CCC(=O)N2 | Carteolol | 0,000000143 | null | 10.1016/j.ejps.2018.03.034 | null | Corneal and conjunctival drug permeability: Systematic comparison and pharmacokinetic impact in the eye | Elsevier BV | 2,018 | 0 | 3 | table 1 |
O=C(O)Cc1ccccc1Nc1c(Cl)cccc1Cl | Diclofenac | 0,00000062 | null | 10.1016/j.ejps.2018.03.034 | null | Corneal and conjunctival drug permeability: Systematic comparison and pharmacokinetic impact in the eye | Elsevier BV | 2,018 | 0 | 3 | table 1 |
OC(Cn1cncn1)(Cn1cncn1)c1ccc(F)cc1F | Fluconazole | 0,000001 | null | 10.1016/j.ejps.2018.03.034 | null | Corneal and conjunctival drug permeability: Systematic comparison and pharmacokinetic impact in the eye | Elsevier BV | 2,018 | 0 | 3 | table 1 |
O=C(c1ccccc1)c1ccc2n1CCC2C(=O)O | Ketorolac | 0,000000349 | null | 10.1016/j.ejps.2018.03.034 | null | Corneal and conjunctival drug permeability: Systematic comparison and pharmacokinetic impact in the eye | Elsevier BV | 2,018 | 0 | 3 | table 1 |
CC1CN(C2CCC(C#N)(c3ccc(F)cc3)CC2)CCC1(C(=O)O)c1ccccc1 | Levocabastine | 0,000000408 | null | 10.1016/j.ejps.2018.03.034 | null | Corneal and conjunctival drug permeability: Systematic comparison and pharmacokinetic impact in the eye | Elsevier BV | 2,018 | 0 | 3 | table 1 |
CCCC1CC(C(=O)NC(C(C)O)C2OC(SC)C(O)C(O)C2O)N(C)C1 | Lincomycin | 0,00000009 | null | 10.1016/j.ejps.2018.03.034 | null | Corneal and conjunctival drug permeability: Systematic comparison and pharmacokinetic impact in the eye | Elsevier BV | 2,018 | 0 | 3 | table 1 |
C=CC1CN2CCC1CC2C(O)c1ccnc2ccc(OC)cc12 | Quinidine | 0,000000868 | null | 10.1016/j.ejps.2018.03.034 | null | Corneal and conjunctival drug permeability: Systematic comparison and pharmacokinetic impact in the eye | Elsevier BV | 2,018 | 0 | 3 | table 1 |
Clc1ccc2nsnc2c1NC1=NCCN1 | Tizanidine | 0,000004704 | null | 10.1016/j.ejps.2018.03.034 | null | Corneal and conjunctival drug permeability: Systematic comparison and pharmacokinetic impact in the eye | Elsevier BV | 2,018 | 0 | 3 | table 1 |
CC(c1ncncc1F)C(O)(Cn1cncn1)c1ccc(F)cc1F | Voriconazole | 0,000003168 | null | 10.1016/j.ejps.2018.03.034 | null | Corneal and conjunctival drug permeability: Systematic comparison and pharmacokinetic impact in the eye | Elsevier BV | 2,018 | 0 | 3 | table 1 |
COc1c(N2C[C@@H]3CCCN[C@@H]3C2)c(F)cc2c(=O)c(C(=O)O)cn(C3CC3)c12 | Moxifloxacin | 0,0000091 | -5,04 | 10.1016/j.talanta.2011.08.060 | null | Quantitative and qualitative prediction of corneal permeability for drug-like compounds | Elsevier BV | 2,011 | 0 | 3 | table 1 |
C[C@H]1COc2c(N3CCN(C)CC3)c(F)cc3c(=O)c(C(=O)O)cn1c23 | Levofloxacin | 0,0000029 | -5,54 | 10.1016/j.talanta.2011.08.060 | null | Quantitative and qualitative prediction of corneal permeability for drug-like compounds | Elsevier BV | 2,011 | 0 | 3 | table 1 |
COc1c(N2CCNC(C)C2)c(F)cc2c(=O)c(C(=O)O)cn(C3CC3)c12 | Gatifloxacin | 0,0000025 | -5,6 | 10.1016/j.talanta.2011.08.060 | null | Quantitative and qualitative prediction of corneal permeability for drug-like compounds | Elsevier BV | 2,011 | 0 | 3 | table 1 |
CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNC(C)C3)c(F)c21 | Lomefloxacin | 0,0000035 | -5,46 | 10.1016/j.talanta.2011.08.060 | null | Quantitative and qualitative prediction of corneal permeability for drug-like compounds | Elsevier BV | 2,011 | 0 | 3 | table 1 |
O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(c2ncccn2)CC1 | Buspirone | 0,0000665 | -4,18 | 10.1016/j.talanta.2011.08.060 | null | Quantitative and qualitative prediction of corneal permeability for drug-like compounds | Elsevier BV | 2,011 | 0 | 3 | table 1 |
Nc1cc(Cl)c(NC2=NCCN2)c(Cl)c1 | Apraclonidine | 0,0000038 | -5,42 | 10.1016/j.talanta.2011.08.060 | null | Quantitative and qualitative prediction of corneal permeability for drug-like compounds | Elsevier BV | 2,011 | 0 | 3 | table 1 |
O=C1OC2(c3ccc(O)cc3Oc3cc(O)ccc32)c2ccccc21 | Fluorescein | 0,000016 | -4,8 | 10.1016/j.talanta.2011.08.060 | null | Quantitative and qualitative prediction of corneal permeability for drug-like compounds | Elsevier BV | 2,011 | 0 | 3 | table 1 |
NC(=O)Cc1cccc(C(=O)c2ccccc2)c1N | Nepafenac | 0,000074 | -4,13 | 10.1016/j.talanta.2011.08.060 | null | Quantitative and qualitative prediction of corneal permeability for drug-like compounds | Elsevier BV | 2,011 | 0 | 3 | table 1 |
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