ai-chem/Co-crystals · Datasets at Hugging Face

Wang2024

10.1016/j.molstruc.2024.139270

1

Z. Wang, S. Li, Y. Tao, R. Zheng, S. Yang, D. Yang, S. Wang, L. Zhang, J. Xing, G. Du, Y. Lu

The novel cocrystals of acacetin with 4,4 ?-bipyridine and 2,2-bipyridine: Crystal structures analysis, stability and dissolution evaluation

Journal of Molecular Structure

2,024

139,270

0

ACT-4,4′-BPY

manuscript

text

2

2:1

manuscript

text

2

Acacetin

manuscript

text

1

COc1ccc(-c2cc(=O)c3c(O)cc(O)cc3o2)cc1

manuscript

figure 1

2

4,4'-Bipyridine

manuscript

text

2

c1cc(-c2ccncc2)ccn1

manuscript

figure 1

2

does not change

manuscript

text

9

Wang2024

10.1016/j.molstruc.2024.139270

1

Z. Wang, S. Li, Y. Tao, R. Zheng, S. Yang, D. Yang, S. Wang, L. Zhang, J. Xing, G. Du, Y. Lu

The novel cocrystals of acacetin with 4,4 ?-bipyridine and 2,2-bipyridine: Crystal structures analysis, stability and dissolution evaluation

Journal of Molecular Structure

2,024

139,270

0

ACT-2,2′-BPY

manuscript

text

2

2:1

manuscript

text

2

Acacetin

manuscript

text

1

COc1ccc(-c2cc(=O)c3c(O)cc(O)cc3o2)cc1

manuscript

figure 1

2

2,2'-Bipyridine

manuscript

text

2

c1ccc(-c2ccccn2)nc1

manuscript

figure 1

2

does not change

manuscript

text

9

Yutani2019

10.3390/cryst9110553

0

Reiko Yutani, Ryotaro Haku, Reiko Teraoka, Chisato Tode, Tatsuo Koide, Shuji Kitagawa, Toshiyasu Sakane, Toshiro Fukami

Comparative Evaluation of the Photostability of Carbamazepine Polymorphs and Cocrystals

Crystals

2,019

553

1

CBZ–SUC

manuscript

text

1

2:1

manuscript

text

3

Carbamazepine

manuscript

text

1

NC(=O)N1c2ccccc2C=Cc2ccccc21

manuscript

figure 1

2

succinic acid

manuscript

text

2

O=C(O)CCC(=O)O

manuscript

figure 1

2

increases

manuscript

figure 4

7

Yutani2019

10.3390/cryst9110553

0

Reiko Yutani, Ryotaro Haku, Reiko Teraoka, Chisato Tode, Tatsuo Koide, Shuji Kitagawa, Toshiyasu Sakane, Toshiro Fukami

Comparative Evaluation of the Photostability of Carbamazepine Polymorphs and Cocrystals

Crystals

2,019

553

1

CBZ–SAC Form I

manuscript

text

1

1:1

manuscript

text

3

Carbamazepine

manuscript

text

1

NC(=O)N1c2ccccc2C=Cc2ccccc21

manuscript

figure 1

2

saccharin

manuscript

text

1

O=C1NS(=O)(=O)c2ccccc21

manuscript

figure 1

2

increases

manuscript

figure 4

7

Yutani2019

10.3390/cryst9110553

0

Reiko Yutani, Ryotaro Haku, Reiko Teraoka, Chisato Tode, Tatsuo Koide, Shuji Kitagawa, Toshiyasu Sakane, Toshiro Fukami

Comparative Evaluation of the Photostability of Carbamazepine Polymorphs and Cocrystals

Crystals

2,019

553

1

CBZ–SAC Form II

manuscript

text

1

1:1

manuscript

text

3

Carbamazepine

manuscript

text

1

NC(=O)N1c2ccccc2C=Cc2ccccc21

manuscript

figure 1

2

saccharin

manuscript

text

1

O=C1NS(=O)(=O)c2ccccc21

manuscript

figure 1

2

decrease

manuscript

figure 4

7

Eesam2020

10.1186/s43094-020-00083-5

0

Shivarani Eesam, Jaswanth S. Bhandaru, Chandana Naliganti, Ravi Kumar Bobbala, Raghuram Rao Akkinepally

Solubility enhancement of carvedilol using drug–drug cocrystallization with hydrochlorothiazide

Future Journal of Pharmaceutical Sciences

2,020

1

CAR-HCT

manuscript

text

3

2:0.5

manuscript

text

3

carvedilol

manuscript

text

1

COc1ccccc1OCCNCC(O)COc1cccc2[nH]c3ccccc3c12

manuscript

figure 1

3

hydrochlorothiazide

manuscript

text

1

NS(=O)(=O)c1cc2c(cc1Cl)NCNS2(=O)=O

manuscript

figure 2

3

null

Ma2021

10.1039/d0ce01551b

1

Xiaoyu Ma, Bingqing Zhu, Zeen Yang, Yuhang Jianga, Xuefeng Mei

Stabilizing photo-sensitive colchicine through rebalancing electron distribution of the reactive tropolone ring

CrystEngComm

2,021

30

0

Col–BSA

manuscript

text

2

1:1

supporting information

text

1

colchicine

manuscript

text

1

COc1cc2c(c(OC)c1OC)-c1ccc(OC)c(=O)cc1C(NC(C)=O)CC2

manuscript

scheme 1

1

benzenesulfonic acid

manuscript

text

2

O=S(=O)(O)c1ccccc1

supporting information

table S1

4

increases

manuscript

figure 3

3

Ma2021

10.1039/d0ce01551b

1

Xiaoyu Ma, Bingqing Zhu, Zeen Yang, Yuhang Jianga, Xuefeng Mei

Stabilizing photo-sensitive colchicine through rebalancing electron distribution of the reactive tropolone ring

CrystEngComm

2,021

30

0

Col–PTA

manuscript

text

2

1:1

supporting information

text

1

colchicine

manuscript

text

1

COc1cc2c(c(OC)c1OC)-c1ccc(OC)c(=O)cc1C(NC(C)=O)CC2

manuscript

scheme 1

1

p-toluenesulfonic acid

manuscript

text

2

Cc1ccc(S(=O)(=O)O)cc1

supporting information

table S1

4

increases

manuscript

figure 3

3

Ma2021

10.1039/d0ce01551b

1

Xiaoyu Ma, Bingqing Zhu, Zeen Yang, Yuhang Jianga, Xuefeng Mei

Stabilizing photo-sensitive colchicine through rebalancing electron distribution of the reactive tropolone ring

CrystEngComm

2,021

30

0

Col–BSA

manuscript

text

2

1:1

supporting information

text

1

colchicine

manuscript

text

1

COc1cc2c(c(OC)c1OC)-c1ccc(OC)c(=O)cc1C(NC(C)=O)CC2

manuscript

scheme 1

1

2-naphthalenesulfonic acid

manuscript

text

2

O=S(=O)(O)c1ccc2ccccc2c1

supporting information

table S1

4

increases

manuscript

figure 3

3

Diniz2024

10.1021/acs.molpharmaceut.4c00393

1

Luan F. Diniz, Paulo S. Carvalho Jr., Mateus A. C. Souza, Renata Diniz, Christian Fernandes

Highly Soluble Dacarbazine Multicomponent Crystals Less Prone to Photodegradation

Molecular Pharmaceutics

2,024

3,661

1

DTIC-HOXA

manuscript

text

1

1:1

supporting information

table S4

12

Dacarbazine

manuscript

text

1

CN(C)N=Nc1[nH]cnc1C(N)=O

manuscript

scheme 1

1

oxalic acid

manuscript

text

2

O=C(O)C(=O)O

manuscript

scheme 1

1

does not change

manuscript

figure 7c

10

Diniz2024

10.1021/acs.molpharmaceut.4c00393

1

Luan F. Diniz, Paulo S. Carvalho Jr., Mateus A. C. Souza, Renata Diniz, Christian Fernandes

Highly Soluble Dacarbazine Multicomponent Crystals Less Prone to Photodegradation

Molecular Pharmaceutics

2,024

3,661

1

DTIC-HMAL

manuscript

text

1

1:1

supporting information

table S4

12

Dacarbazine

manuscript

text

1

CN(C)N=Nc1[nH]cnc1C(N)=O

manuscript

scheme 1

1

maleic acid

manuscript

text

2

O=C(O)/C=C\C(=O)O

manuscript

scheme 1

1

does not change

manuscript

figure 7c

10

Diniz2024

10.1021/acs.molpharmaceut.4c00393

1

Luan F. Diniz, Paulo S. Carvalho Jr., Mateus A. C. Souza, Renata Diniz, Christian Fernandes

Highly Soluble Dacarbazine Multicomponent Crystals Less Prone to Photodegradation

Molecular Pharmaceutics

2,024

3,661

1

DTIC-H2FUM

manuscript

text

1

1:1

supporting information

table S4

12

Dacarbazine

manuscript

text

1

CN(C)N=Nc1[nH]cnc1C(N)=O

manuscript

scheme 1

1

fumaric acid

manuscript

text

2

O=C(O)/C=C/C(=O)O

manuscript

scheme 1

1

does not change

manuscript

figure 7c

10

Diniz2024

10.1021/acs.molpharmaceut.4c00393

1

Luan F. Diniz, Paulo S. Carvalho Jr., Mateus A. C. Souza, Renata Diniz, Christian Fernandes

Highly Soluble Dacarbazine Multicomponent Crystals Less Prone to Photodegradation

Molecular Pharmaceutics

2,024

3,661

1

DTIC-H2SUС

manuscript

text

1

1:1

supporting information

table S4

12

Dacarbazine

manuscript

text

1

CN(C)N=Nc1[nH]cnc1C(N)=O

manuscript

scheme 1

1

succinic acid

manuscript

text

2

O=C(O)CCC(=O)O

manuscript

scheme 1

1

does not change

manuscript

figure 7c

10

Diniz2024

10.1021/acs.molpharmaceut.4c00393

1

Luan F. Diniz, Paulo S. Carvalho Jr., Mateus A. C. Souza, Renata Diniz, Christian Fernandes

Highly Soluble Dacarbazine Multicomponent Crystals Less Prone to Photodegradation

Molecular Pharmaceutics

2,024

3,661

1

DTIC-HCIT

manuscript

text

1

2:1

supporting information

table S4

12

Dacarbazine

manuscript

text

1

CN(C)N=Nc1[nH]cnc1C(N)=O

manuscript

scheme 1

1

citric acid

manuscript

text

2

O=C(O)CC(O)(CC(=O)O)C(=O)O

manuscript

scheme 1

1

does not change

manuscript

figure 7c

10

Hao2022

10.1039/D2CE00597B

1

Xinghui Hao,Jinhui Li, Chenguang Wang, Xinghua Zhao, Xin He, Changquan Calvin Sun

Profoundly improved photostability of dimetronidazole by cocrystallization

CrystEngComm

2,022

6,165

0

DMZ-SAC

manuscript

text

2

1:1

manuscript

text

1

Dimetronidazole

manuscript

text

1

Cc1ncc([N+](=O)[O-])n1C

manuscript

scheme 1

1

saccharin

manuscript

text

1

O=C1NS(=O)(=O)c2ccccc21

manuscript

scheme 1

1

increases

manuscript

figure 7c

6

Putra2018

10.1021/acs.cgd.7b01371

1

Okky Dwichandra Putra, Daiki Umeda, Yuda Prasetya Nugraha, Kazuya Nango, Etsuo Yonemochi, Hidehiro Uekusa

Simultaneous Improvement of Epalrestat Photostability and Solubility via Cocrystallization: A Case Study

Crystal Growth & Design

2,018

373

0

EPR-BET

manuscript

text

3

1:1

manuscript

text

2

Epalrestat

manuscript

text

1

CC(=C\c1ccccc1)/C=C1/SC(=S)N(CC(=O)O)C1=O

manuscript

chart 1

1

betaine

manuscript

text

1

C[N+](C)(C)CC(=O)[O-]

manuscript

chart 1

1

increases

manuscript

text

6

Li2022

10.1021/acs.cgd.2c00533

1

Min Li, Jingjing Sun, Wenjie Kuang, Lina Zhou, Dandan Han, Junbo Gong

Drug–Drug Multicomponent Crystals of Epalrestat: A Novel Form of the Drug Combination and Improved Solubility and Photostability of Epalrestat

Crystal Growth & Design

2,022

5,027

0

EP-ED

manuscript

text

2

1:1

manuscript

text

4

Epalrestat

manuscript

text

1

CC(=C\c1ccccc1)/C=C1/SC(=S)N(CC(=O)O)C1=O

manuscript

scheme 1

2

edaravone

manuscript

text

1

CC1=NN(c2ccccc2)C(=O)C1

manuscript

scheme 1

2

increases

manuscript

text

5

Li2022

10.1021/acs.cgd.2c00533

1

Min Li, Jingjing Sun, Wenjie Kuang, Lina Zhou, Dandan Han, Junbo Gong

Drug–Drug Multicomponent Crystals of Epalrestat: A Novel Form of the Drug Combination and Improved Solubility and Photostability of Epalrestat

Crystal Growth & Design

2,022

5,027

0

EP-PR SC MH

manuscript

text

2

null

Epalrestat

manuscript

text

1

CC(=C\c1ccccc1)/C=C1/SC(=S)N(CC(=O)O)C1=O

manuscript

scheme 1

2

pregabalin

manuscript

text

1

CC(C)CC(CN)CC(=O)O

manuscript

scheme 1

2

increases

manuscript

text

5

Sun2025

10.1016/j.molstruc.2025.141678

1

Zhong-hua Sun, Zhao Yang, Yan Zhang, Hong Xu, Ru-mei Liu, Da-zhong Ding, Yang Li f, Yun-jie Zhu, Min Li, Ping Leng

Synthesis, characterization, solubility and photostability enhancement of felodipine co-crystals featuring a novel single-crystal structure

Journal of Molecular Structure

2,025

141,678

0

FEL–BPE

manuscript

text

1

null

felodipine

manuscript

text

1

CCOC(=O)C1=C(C)NC(C)=C(C(=O)OC)C1c1cccc(Cl)c1Cl

manuscript

figure 1

2

1,2-bis(4-pyridyl)ethylene

manuscript

text

1

c1cc(CCc2ccncc2)ccn1

manuscript

figure 1

2

increases

manuscript

table 4

7

Liu2024

10.1016/j.ejpb.2024.114464

1

Lixin Liu, Yuning Wang, Jiuyi Sun, Yunan Zhang, Xiangyu Zhang, Lili Wu, Yingli Liu, Xuan Zhang, Yidi Xia, Qiumei Zhang, Ning Gao

Improved photostability, solubility, hygroscopic stability and antimicrobial activity of fleroxacin by synthesis of fleroxacin-D-tartaric acid pharmaceutical salt

European Journal of Pharmaceutics and Biopharmaceutics

2,024

114,464

0

FL-D-TT

manuscript

text

1

1:1

null

fleroxacin

manuscript

text

1

CN1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(CCF)c3c2F)CC1

manuscript

scheme 1

2

D-tartaric

manuscript

text

1

O=C(O)C(O)C(O)C(=O)O

manuscript

scheme 1

2

increases

manuscript

figure 14

8

AbrahamMiranda2019

10.1021/acs.cgd.8b01556

1

Julieta Abraham Miranda, Claudia Garnero, Ana K. Chattah, Yara Santiago de Oliveira, Alejandro P. Ayala, Marcela R. Longhi

Furosemide:Triethanolamine Salt as a Strategy To Improve the Biopharmaceutical Properties and Photostability of the Drug

Crystal Growth & Design

2,019

2,060

0

FUR:TEA

manuscript

text

2

1:1

null

Furosemide

manuscript

text

1

NS(=O)(=O)c1cc(C(=O)O)c(NCc2ccco2)cc1Cl

manuscript

scheme 1

1

triethanolamine

manuscript

text

2

OCCN(CCO)CCO

manuscript

scheme 1

1

increases

manuscript

table 2

7

Teraoka2019

10.1248/cpb.c18-00812

0

Reiko Teraoka, Toshiro Fukami, Takayuki Furuishi, Hiromasa Nagase, Haruhisa Ueda, Chisato Tode, Reiko Yutani, Shuji Kitagawa, Toshiyasu Sakane

Improving the Solid-State Photostability of Furosemide by Its Cocrystal Formation

Chemical and Pharmaceutical Bulletin

2,019

940

1

FUR-CAF

manuscript

text

1

1 : 1

manuscript

text

1

Furosemide

manuscript

text

1

NS(=O)(=O)c1cc(C(=O)O)c(NCc2ccco2)cc1Cl

manuscript

chart 1

2

caffeine

manuscript

text

1

Cn1c(=O)c2c(ncn2C)n(C)c1=O

manuscript

chart 1

2

increases

manuscript

figure 3

4

Teraoka2019

10.1248/cpb.c18-00812

0

Reiko Teraoka, Toshiro Fukami, Takayuki Furuishi, Hiromasa Nagase, Haruhisa Ueda, Chisato Tode, Reiko Yutani, Shuji Kitagawa, Toshiyasu Sakane

Improving the Solid-State Photostability of Furosemide by Its Cocrystal Formation

Chemical and Pharmaceutical Bulletin

2,019

940

1

FUR-UREA

manuscript

text

1

1 : 1

manuscript

text

1

Furosemide

manuscript

text

1

NS(=O)(=O)c1cc(C(=O)O)c(NCc2ccco2)cc1Cl

manuscript

chart 1

2

urea

manuscript

text

1

NC(N)=O

manuscript

chart 1

2

decreases

manuscript

figure 3

4

Teraoka2019

10.1248/cpb.c18-00812

0

Reiko Teraoka, Toshiro Fukami, Takayuki Furuishi, Hiromasa Nagase, Haruhisa Ueda, Chisato Tode, Reiko Yutani, Shuji Kitagawa, Toshiyasu Sakane

Improving the Solid-State Photostability of Furosemide by Its Cocrystal Formation

Chemical and Pharmaceutical Bulletin

2,019

940

1

FUR-NIC

manuscript

text

1

1 : 1

manuscript

text

1

Furosemide

manuscript

text

1

NS(=O)(=O)c1cc(C(=O)O)c(NCc2ccco2)cc1Cl

manuscript

chart 1

2

nicotinamide

manuscript

text

1

NC(=O)c1cccnc1

manuscript

chart 1

2

increases

manuscript

figure 3

4

Shinozaki2019

10.1016/j.xphs.2019.02.014

0

Taeko Shinozaki, Makoto Ono, Kenjirou Higashi, Kunikazu Moribe

A Novel Drug-Drug Cocrystal of Levofloxacin and Metacetamol: Reduced Hygroscopicity and Improved Photostability of Levofloxacin

Journal of Pharmaceutical Sciences

2,019

2,383

0

LVFX-AMAP

manuscript

text

1

1:1

manuscript

text

1

Levofloxacin

manuscript

text

1

C[C@H]1COc2c(N3CCN(C)CC3)c(F)cc3c(=O)c(C(=O)O)cn1c23

manuscript

figure 1

2

metacetamol

manuscript

text

1

CC(=O)Nc1cccc(O)c1

manuscript

figure 1

2

increases

manuscript

table 1

7

Nugrahani2023

10.3390/pharmaceutics15010124

0

Ilma Nugrahani, Muhammad Ramadhan Sulaiman, Slamet Ibrahim

Stability and Antibiotic Potency Improvement of Levofloxacin by Producing New Salts with 2,6- and 3,5-Dihydroxybenzoic Acid and Their Comprehensive Structural Study

Pharmaceutics

2,023

124

1

LF-26

manuscript

text

1

1:1

manuscript

text

1

Levofloxacin

manuscript

text

1

C[C@H]1COc2c(N3CCN(C)CC3)c(F)cc3c(=O)c(C(=O)O)cn1c23

manuscript

figure 7

10

2,6-dihydroxybenzoic acid

manuscript

text

1

O=C(O)c1c(O)cccc1O

manuscript

figure 7

10

increases

manuscript

figure 11

15

Nugrahani2023

10.3390/pharmaceutics15010124

0

Ilma Nugrahani, Muhammad Ramadhan Sulaiman, Slamet Ibrahim

Stability and Antibiotic Potency Improvement of Levofloxacin by Producing New Salts with 2,6- and 3,5-Dihydroxybenzoic Acid and Their Comprehensive Structural Study

Pharmaceutics

2,023

124

1

LF-35

manuscript

text

1

1:1

manuscript

text

1

Levofloxacin

manuscript

text

1

C[C@H]1COc2c(N3CCN(C)CC3)c(F)cc3c(=O)c(C(=O)O)cn1c23

manuscript

figure 7

10

3,5-dihydroxybenzoic acid

manuscript

text

1

O=C(O)c1cc(O)cc(O)c1

manuscript

figure 7

10

increases

manuscript

figure 11

15

Nugrahani2024

10.1016/j.heliyon.2024.e33280

1

Ilma Nugrahani, Hidehiro Uekusa, Hironaga Oyama, Agnesya Namira Laksana

New proportion of levofloxacin citrate: Structural, physicochemical properties, and potency studies

Heliyon

2,024

null

1

LF – CA

manuscript

text

1

2:1

manuscript

table 1

6

Levofloxacin

manuscript

text

1

C[C@H]1COc2c(N3CCN(C)CC3)c(F)cc3c(=O)c(C(=O)O)cn1c23

null

citric acid

manuscript

text

1

O=C(O)CC(O)(CC(=O)O)C(=O)O

null

increases

manuscript

figure 11

12

Xie2024

10.3390/molecules29102208

0

Yifei Xie, Lixiang Gong, Yue Tao, Baoxi Zhang, Li Zhang, Shiying Yang, Dezhi Yang, Yang Lu, Guanhua Du

NewCocrystals of Ligustrazine: Enhancing Hygroscopicity and Stability

Molecules

2,024

2,208

1

TMP-PABA

manuscript

text

1

1:2

manuscript

text

1

ligustrazine

manuscript

text

1

Cc1nc(C)c(C)nc1C

manuscript

figure 1

2

P-aminobenzoic acid

manuscript

text

1

Nc1ccc(C(=O)O)cc1

manuscript

figure 1

2

increases

manuscript

text

9

Xie2024

10.3390/molecules29102208

0

Yifei Xie, Lixiang Gong, Yue Tao, Baoxi Zhang, Li Zhang, Shiying Yang, Dezhi Yang, Yang Lu, Guanhua Du

NewCocrystals of Ligustrazine: Enhancing Hygroscopicity and Stability

Molecules

2,024

2,208

1

TMP-MABA

manuscript

text

1

1.5:1

manuscript

text

1

ligustrazine

manuscript

text

1

Cc1nc(C)c(C)nc1C

manuscript

figure 1

2

3-Aminobenzoic acid

manuscript

text

1

Nc1cccc(C(=O)O)c1

manuscript

figure 1

2

increases

manuscript

text

9

Xie2024

10.3390/molecules29102208

0

Yifei Xie, Lixiang Gong, Yue Tao, Baoxi Zhang, Li Zhang, Shiying Yang, Dezhi Yang, Yang Lu, Guanhua Du

NewCocrystals of Ligustrazine: Enhancing Hygroscopicity and Stability

Molecules

2,024

2,208

1

TMP-DNBA

manuscript

text

1

0.5:1

manuscript

text

1

ligustrazine

manuscript

text

1

Cc1nc(C)c(C)nc1C

manuscript

figure 1

2

3,5-Dinitrobenzoic acid

manuscript

text

1

O=C(O)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1

manuscript

figure 1

2

increases

manuscript

text

9

Zheng2024

10.1021/acsomega.4c03864

1

Chenxuan Zheng, Hao Wang, Ziyao Xiao, Zhixiong Sun, Junjie Bao, Wenjuan Dai, Qi Zhang, Xuefeng Mei

Cocrystal of Lutein with Improved Stability and Bioavailability

ACS Omega

2,024

36,389

1

PLT-APC

manuscript

text

2

1:1

manuscript

text

5

Lutein

manuscript

text

1

CC1=CC(O)CC(C)(C)C1/C=C/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CC(O)CC1(C)C

manuscript

scheme 1

1

adipic acid

manuscript

text

1

O=C(O)CCCCC(=O)O

null

increases

manuscript

figure 5b

5

Zheng2024

10.1021/acsomega.4c03864

1

Chenxuan Zheng, Hao Wang, Ziyao Xiao, Zhixiong Sun, Junjie Bao, Wenjuan Dai, Qi Zhang, Xuefeng Mei

Cocrystal of Lutein with Improved Stability and Bioavailability

ACS Omega

2,024

36,389

1

MLT-APC

manuscript

text

2

1:1

manuscript

text

5

Lutein

manuscript

text

1

CC1=CC(O)CC(C)(C)C1/C=C/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CC(O)CC1(C)C

manuscript

scheme 1

1

adipic acid

manuscript

text

1

O=C(O)CCCCC(=O)O

null

increases

manuscript

figure 5b

5

Kawabata2023

10.1016/j.jpap.2023.100172

1

Kohei Kawabata, Ayano Miyoshi, Hiroyuki Nishi

Cocrystallization with nicotinamide promotes naproxen photodegradation in the solid-state

Journal of Photochemistry and Photobiology

2,023

100,172

1

NPX-NA

manuscript

text

1

2:1

null

naproxen

manuscript

text

1

COc1ccc2cc([C@H](C)C(=O)O)ccc2c1

manuscript

figure 1

2

nicotinamide

manuscript

text

1

NC(=O)c1cccnc1

manuscript

figure 1

2

decreases

manuscript

text

6

Yu2017

10.1039/C7CC06992H

1

Qihui Yu, Zhicheng Yan, Junjie Bao, Jian-Rong Wang, Xuefeng Mei

Taming photo-induced oxidation degradation of dihydropyridine drugs through cocrystallization

Chemical Communications

2,017

12,266

0

NFD·INA form I

manuscript

text

3

1:1

manuscript

text

3

nifedipine

manuscript

text

2

COC(=O)C1=C(C)NC(C)=C(C(=O)OC)C1c1ccccc1[N+](=O)[O-]

manuscript

scheme 1

3

isonicotinamide

manuscript

text

2

NC(=O)c1ccncc1

supporting information

scheme s1

6

increases

manuscript

figure 1c

4

Yu2017

10.1039/C7CC06992H

1

Qihui Yu, Zhicheng Yan, Junjie Bao, Jian-Rong Wang, Xuefeng Mei

Taming photo-induced oxidation degradation of dihydropyridine drugs through cocrystallization

Chemical Communications

2,017

12,266

0

NFD·INA form II

manuscript

text

3

1:1

manuscript

text

3

nifedipine

manuscript

text

2

COC(=O)C1=C(C)NC(C)=C(C(=O)OC)C1c1ccccc1[N+](=O)[O-]

manuscript

scheme 1

3

isonicotinamide

manuscript

text

2

NC(=O)c1ccncc1

supporting information

scheme s1

6

decreases

manuscript

figure 1c

4

Vangala2011

10.1039/C0CE00772B

1

Venu R. Vangala, Pui Shan Chowa, Reginald B. H. Tan

Characterization, physicochemical and photo-stability of a co-crystal involving an antibiotic drug, nitrofurantoin, and 4-hydroxybenzoic acid

CrystEngComm

2,011

759

0

NF-4HBA

manuscript

text

2

1 : 1

manuscript

text

1

Nitrofurantoin

manuscript

text

1

O=C1CN(/N=C/c2ccc([N+](=O)[O-])o2)C(=O)N1

manuscript

scheme 1

1

4-hydroxybenzoic acid

manuscript

text

1

O=C(O)c1ccc(O)cc1

manuscript

scheme 1

1

increases

manuscript

figure 5

3

Vangala2012

10.1021/cg300887p

1

Venu R. Vangala, Pui Shan Chow, Reginald B. H. Tan

Co-Crystals and Co-Crystal Hydrates of the Antibiotic Nitrofurantoin: Structural Studies and Physicochemical Properties

Crystal Growth & Design

2,012

5,925

0

NF-3ABA

manuscript

text

1

1:1

manuscript

text

5

Nitrofurantoin

manuscript

text

1

O=C1CN(/N=C/c2ccc([N+](=O)[O-])o2)C(=O)N1

manuscript

scheme 1

2

3-aminobenzoic acid

manuscript

text

1

Nc1cccc(C(=O)O)c1

manuscript

scheme 1

2

increases

manuscript

figure 15

12

Vangala2012

10.1021/cg300887p

1

Venu R. Vangala, Pui Shan Chow, Reginald B. H. Tan

Co-Crystals and Co-Crystal Hydrates of the Antibiotic Nitrofurantoin: Structural Studies and Physicochemical Properties

Crystal Growth & Design

2,012

5,925

0

NF-4ABA

manuscript

text

1

1:1

manuscript

text

5

Nitrofurantoin

manuscript

text

1

O=C1CN(/N=C/c2ccc([N+](=O)[O-])o2)C(=O)N1

manuscript

scheme 1

2

4-aminobenzoic acid

manuscript

text

1

Nc1ccc(C(=O)O)cc1

manuscript

scheme 1

2

increases

manuscript

figure 15

12

Vangala2012

10.1021/cg300887p

1

Venu R. Vangala, Pui Shan Chow, Reginald B. H. Tan

Co-Crystals and Co-Crystal Hydrates of the Antibiotic Nitrofurantoin: Structural Studies and Physicochemical Properties

Crystal Growth & Design

2,012

5,925

0

NF-UREA

manuscript

text

1

1:1

manuscript

text

6

Nitrofurantoin

manuscript

text

1

O=C1CN(/N=C/c2ccc([N+](=O)[O-])o2)C(=O)N1

manuscript

scheme 1

2

urea

manuscript

text

1

NC(N)=O

manuscript

scheme 1

2

increases

manuscript

figure 15

12

Vangala2012

10.1021/cg300887p

1

Venu R. Vangala, Pui Shan Chow, Reginald B. H. Tan

Co-Crystals and Co-Crystal Hydrates of the Antibiotic Nitrofurantoin: Structural Studies and Physicochemical Properties

Crystal Growth & Design

2,012

5,925

0

NF-4HBAM

manuscript

text

1

1:2

manuscript

text

6

Nitrofurantoin

manuscript

text

1

O=C1CN(/N=C/c2ccc([N+](=O)[O-])o2)C(=O)N1

manuscript

scheme 1

2

4-hydroxybenzamide

manuscript

text

1

NC(=O)c1ccc(O)cc1

manuscript

scheme 1

2

increases

manuscript

figure 15

12

Surov2022

10.1021/acs.cgd.2c00044

1

Artem O. Surov, Alexander P. Voronin, Ksenia V. Drozd, Tatyana V. Volkova, Nikita Vasilev, Dmitriy Batov, Andrei V. Churakov, German L. Perlovich

Extending the Range of Nitrofurantoin Solid Forms: Effect of Molecular and Crystal Structure on Formation Thermodynamics and Physicochemical Properties

Crystal Growth & Design

2,022

2,569

0

[NFT-iNA] (1:1)

manuscript

text

3

1:1

manuscript

text

2

Nitrofurantoin

manuscript

text

1

O=C1CN(/N=C/c2ccc([N+](=O)[O-])o2)C(=O)N1

manuscript

figure 1

2

isonicotinamide

manuscript

text

1

NC(=O)c1ccncc1

manuscript

figure 1

2

increases

supporting inofrmation

figure s11

20

Surov2022

10.1021/acs.cgd.2c00044

1

Artem O. Surov, Alexander P. Voronin, Ksenia V. Drozd, Tatyana V. Volkova, Nikita Vasilev, Dmitriy Batov, Andrei V. Churakov, German L. Perlovich

Extending the Range of Nitrofurantoin Solid Forms: Effect of Molecular and Crystal Structure on Formation Thermodynamics and Physicochemical Properties

Crystal Growth & Design

2,022

2,569

0

[NFT-PicAm](1:1)

manuscript

text

3

1:1

manuscript

text

2

Nitrofurantoin

manuscript

text

1

O=C1CN(/N=C/c2ccc([N+](=O)[O-])o2)C(=O)N1

manuscript

figure 1

2

picolinamide

manuscript

text

1

NC(=O)c1ccccn1

manuscript

figure 1

2

increases

supporting inofrmation

figure s11

20

Surov2022

10.1021/acs.cgd.2c00044

1

Artem O. Surov, Alexander P. Voronin, Ksenia V. Drozd, Tatyana V. Volkova, Nikita Vasilev, Dmitriy Batov, Andrei V. Churakov, German L. Perlovich

Extending the Range of Nitrofurantoin Solid Forms: Effect of Molecular and Crystal Structure on Formation Thermodynamics and Physicochemical Properties

Crystal Growth & Design

2,022

2,569

0

[NFT-2AmBZA](1:1)

manuscript

text

2

1:1

manuscript

text

2

Nitrofurantoin

manuscript

text

1

O=C1CN(/N=C/c2ccc([N+](=O)[O-])o2)C(=O)N1

manuscript

figure 1

2

2-aminobenzamide

manuscript

text

1

NC(=O)c1ccccc1N

manuscript

figure 1

2

increases

supporting inofrmation

figure s11

20

Surov2022

10.1021/acs.cgd.2c00044

1

Artem O. Surov, Alexander P. Voronin, Ksenia V. Drozd, Tatyana V. Volkova, Nikita Vasilev, Dmitriy Batov, Andrei V. Churakov, German L. Perlovich

Extending the Range of Nitrofurantoin Solid Forms: Effect of Molecular and Crystal Structure on Formation Thermodynamics and Physicochemical Properties

Crystal Growth & Design

2,022

2,569

0

[NFT-2OHBZA](1:1)

manuscript

text

3

1:1

manuscript

text

2

Nitrofurantoin

manuscript

text

1

O=C1CN(/N=C/c2ccc([N+](=O)[O-])o2)C(=O)N1

manuscript

figure 1

2

2-hydroxybenzamide

manuscript

text

1

NC(=O)c1ccccc1O

manuscript

figure 1

2

increases

supporting inofrmation

figure s11

20

Li2020

10.1002/anie.202009714

1

Shuzhen Li, Bo Lu, Xiaoyu Fang, Dongpeng Yan

Manipulating Light-Induced Dynamic Macro-Movement and Static Photonic Properties within 1D Isostructural Hydrogen-Bonded Molecular Cocrystals

Angewandte Chemie International Edition

2,020

22,623

1

NVP-THA

manuscript

text

1

1:2

manuscript

text

1

4-(1-naphthylvinyl)pyridine

manuscript

text

1

C(=C/c1cccc2ccccc12)\c1ccncc1

manuscript

figure 1

2

2,3,5,6-tetrafluorobenzoic acid

manuscript

figure 1

2

O=C(O)c1c(F)c(F)cc(F)c1F

manuscript

figure 1

2

does not change

manuscript

text

1

Cugovčan2017

10.1016/j.jpba.2017.01.025

1

Martina Cugovčan, Jasna Jablan, Jasmina Lovrić, Dominik Cinčić, Nives Galić, Mario Jug

Biopharmaceutical characterization of praziquantel cocrystals and cyclodextrin complexes prepared by grinding

Journal of Pharmaceutical and Biomedical Analysis

2,017

42

1

PZQ/MA

manuscript

text

4

1:1

manuscript

table 1

4

praziquantel

manuscript

text

1

O=C(C1CCCCC1)N1CC(=O)N2CCc3ccccc3C2C1

null

malic acid

manuscript

text

2

O=C(O)CC(O)C(=O)O

null

decreases

manuscript

figure 5b

9

Ambrogi2014

10.1021/la5033898

0

Valeria Ambrogi, Morena Nocchetti, Loredana Latterini

Promethazine–Montmorillonite Inclusion Complex To Enhance Drug Photostability

Langmuir

2,014

14,612

0

MONT-PRO

manuscript

text

1

null

Promethazine

manuscript

text

1

CC(CN1c2ccccc2Sc2ccccc21)N(C)C

manuscript

figure 1

1

Montmorillonite

null

does not change

manuscript

figure 10

7

Qu2024

10.1016/j.cej.2024.151902

1

Haibin Qu, Ye Gao, Lina Zhou, Songgu Wu, Junbo Gong

Construction of fungicide nano delivery platform through crystal engineering for sustainable fungal control

Chemical Engineering Journal

2,024

151,902

1

PYR-FMA

manuscript

text

3

1:2

supporting information

text

3

pyrimethanil

manuscript

text

1

Cc1cc(C)nc(Nc2ccccc2)n1

manuscript

figure 1

3

fumaric acid

manuscript

text

2

O=C(O)/C=C/C(=O)O

manuscript

figure 1

3

increases

manuscript

figure 7b

9

Qu2024

10.1016/j.cej.2024.151902

1

Haibin Qu, Ye Gao, Lina Zhou, Songgu Wu, Junbo Gong

Construction of fungicide nano delivery platform through crystal engineering for sustainable fungal control

Chemical Engineering Journal

2,024

151,902

1

PYR-3IA

manuscript

text

3

1:1

supporting information

text

3

pyrimethanil

manuscript

text

1

Cc1cc(C)nc(Nc2ccccc2)n1

manuscript

figure 1

3

indole-3-acetic acid

manuscript

text

2

O=C(O)Cc1c[nH]c2ccccc12

manuscript

figure 1

3

increases

manuscript

figure 7b

9

Dhakar2019

10.3390/pharmaceutics11100545

0

Nilesh Kumar Dhakar, Adrián Matencio,Fabrizio Caldera, Monica Argenziano, Roberta Cavalli, Chiara Dianzani, Marco Zanetti, José Manuel López-Nicolás, Francesco Trotta

Comparative Evaluation of Solubility, Cytotoxicity and Photostability Studies of Resveratrol and Oxyresveratrol Loaded Nanosponge

Pharmaceutics

2,019

545

1

RES-NS

manuscript

text

6

null

resveratrol

manuscript

text

1

Oc1ccc(C=Cc2cc(O)cc(O)c2)cc1

manuscript

figure 1

2

nanosponge

manuscript

text

1

null

increases

manuscript

figure 9a

10

Dhakar2019

10.3390/pharmaceutics11100545

0

Nilesh Kumar Dhakar, Adrián Matencio,Fabrizio Caldera, Monica Argenziano, Roberta Cavalli, Chiara Dianzani, Marco Zanetti, José Manuel López-Nicolás, Francesco Trotta

Comparative Evaluation of Solubility, Cytotoxicity and Photostability Studies of Resveratrol and Oxyresveratrol Loaded Nanosponge

Pharmaceutics

2,019

545

1

OXY-NS

manuscript

text

6

null

oxyresveratrol

manuscript

text

1

Oc1cc(O)cc(C=Cc2ccc(O)cc2O)c1

manuscript

figure 1

2

nanosponge

manuscript

text

1

null

increases

manuscript

figure 9b

10

Muthaiyan2024

10.1021/acs.cgd.4c00855

1

Muthukumari Muthaiyan, Fayaz T. K. S, Gowtham Kenguva, Aditya Kumar Prajapati, Rambabu Dandela, Vladimir V. Chernyshev, Palash Sanphui

New Multicomponent Solid Forms of the Antitumor Drug Ripretinib: The Role of Conformations in Dictating Dissolution and Photostability

Crystal Growth & Design

2,024

7,617

0

RIP-HCl

manuscript

text

2

1:1

manuscript

text

5

Ripretinib

manuscript

text

1

CCn1c(=O)c(-c2cc(NC(=O)Nc3ccccc3)c(F)cc2Br)cc2cnc(NC)cc21

manuscript

figure 1

2

HCl

manuscript

text

2

Cl

manuscript

figure 1

2

increases

manuscript

figure 10

12

Muthaiyan2024

10.1021/acs.cgd.4c00855

1

Muthukumari Muthaiyan, Fayaz T. K. S, Gowtham Kenguva, Aditya Kumar Prajapati, Rambabu Dandela, Vladimir V. Chernyshev, Palash Sanphui

New Multicomponent Solid Forms of the Antitumor Drug Ripretinib: The Role of Conformations in Dictating Dissolution and Photostability

Crystal Growth & Design

2,024

7,617

0

RIP-FOR

manuscript

text

3

1:2

manuscript

text

7

Ripretinib

manuscript

text

1

CCn1c(=O)c(-c2cc(NC(=O)Nc3ccccc3)c(F)cc2Br)cc2cnc(NC)cc21

manuscript

figure 1

2

formic acid

manuscript

text

3

O=CO

manuscript

figure 1

2

increases

manuscript

figure 10

12

Muthaiyan2024

10.1021/acs.cgd.4c00855

1

Muthukumari Muthaiyan, Fayaz T. K. S, Gowtham Kenguva, Aditya Kumar Prajapati, Rambabu Dandela, Vladimir V. Chernyshev, Palash Sanphui

New Multicomponent Solid Forms of the Antitumor Drug Ripretinib: The Role of Conformations in Dictating Dissolution and Photostability

Crystal Growth & Design

2,024

7,617

0

RIP-AA

manuscript

text

3

1:1

manuscript

text

7

Ripretinib

manuscript

text

1

CCn1c(=O)c(-c2cc(NC(=O)Nc3ccccc3)c(F)cc2Br)cc2cnc(NC)cc21

manuscript

figure 1

2

acetic acid

manuscript

text

3

CC(=O)O

manuscript

figure 1

2

increases

manuscript

figure 10

12

Muthaiyan2024

10.1021/acs.cgd.4c00855

1

Muthukumari Muthaiyan, Fayaz T. K. S, Gowtham Kenguva, Aditya Kumar Prajapati, Rambabu Dandela, Vladimir V. Chernyshev, Palash Sanphui

New Multicomponent Solid Forms of the Antitumor Drug Ripretinib: The Role of Conformations in Dictating Dissolution and Photostability

Crystal Growth & Design

2,024

7,617

0

RIP-DHBA

manuscript

text

3

1:1

null

Ripretinib

manuscript

text

1

CCn1c(=O)c(-c2cc(NC(=O)Nc3ccccc3)c(F)cc2Br)cc2cnc(NC)cc21

manuscript

figure 1

2

2,6-dihydroxybenzoic acid

manuscript

text

4

O=C(O)c1c(O)cccc1O

manuscript

figure 1

2

increases

manuscript

figure 10

12

Muthaiyan2024

10.1021/acs.cgd.4c00855

1

Muthukumari Muthaiyan, Fayaz T. K. S, Gowtham Kenguva, Aditya Kumar Prajapati, Rambabu Dandela, Vladimir V. Chernyshev, Palash Sanphui

New Multicomponent Solid Forms of the Antitumor Drug Ripretinib: The Role of Conformations in Dictating Dissolution and Photostability

Crystal Growth & Design

2,024

7,617

0

RIP-FER

manuscript

text

3

1:1

manuscript

text

9

Ripretinib

manuscript

text

1

CCn1c(=O)c(-c2cc(NC(=O)Nc3ccccc3)c(F)cc2Br)cc2cnc(NC)cc21

manuscript

figure 1

2

ferulic acid

manuscript

text

3

COc1cc(/C=C/C(=O)O)ccc1O

manuscript

figure 1

2

increases

manuscript

figure 10

12

Muthusamy2024

10.1016/j.xphs.2023.10.024

1

Anantha Rajmohan Muthusamy, Amit Singha, Meenakshi Sundaram Soma Sundarama, Yogesh Wagha, Alexandr Jegorovb, Arvind Kumar Jain

In-Silico Aided Screening and Characterization Results in Stability Enhanced Novel Roxadustat Co-Crystal

Journal of Pharmaceutical Sciences

2,024

1,190

0

RXD-NA

manuscript

text

1

1:1

manuscript

text

8

Roxadustat

manuscript

text

1

Cc1nc(C(=O)NCC(=O)O)c(O)c2ccc(Oc3ccccc3)cc12

manuscript

figure 1

3

nicotinamide

manuscript

text

1

NC(=O)c1cccnc1

manuscript

figure 1

3

increases

manuscript

table 6

10

Kalle2024

10.1021/acs.cgd.4c01197

1

Paulina Kalle, Stanislav I. Bezzubov, Lyudmila G. Kuzmina, Andrei V. Churakov

New Insights into the Structure, Thermal Properties, and Photostability of Industrially Relevant Salts of Sorbic Acid

Crystal Growth & Design

2,024

9,173

0

NaSorb

manuscript

text

2

null

Sorbic Acid

manuscript

text

1

C/C=C/C=C/C(=O)O

null

sodium

manuscript

text

2

null

does not change

supporting information

figure s2

6

Kalle2024

10.1021/acs.cgd.4c01197

1

Paulina Kalle, Stanislav I. Bezzubov, Lyudmila G. Kuzmina, Andrei V. Churakov

New Insights into the Structure, Thermal Properties, and Photostability of Industrially Relevant Salts of Sorbic Acid

Crystal Growth & Design

2,024

9,173

0

KSorb

manuscript

text

2

null

Sorbic Acid

manuscript

text

1

C/C=C/C=C/C(=O)O

null

Potassium

manuscript

text

2

null

decreases

supporting information

figure s3

7

Kalle2024

10.1021/acs.cgd.4c01197

1

Paulina Kalle, Stanislav I. Bezzubov, Lyudmila G. Kuzmina, Andrei V. Churakov

New Insights into the Structure, Thermal Properties, and Photostability of Industrially Relevant Salts of Sorbic Acid

Crystal Growth & Design

2,024

9,173

0

CaSorb

manuscript

text

2

null

Sorbic Acid

manuscript

text

1

C/C=C/C=C/C(=O)O

null

calcium

manuscript

text

2

null

does not change

supporting information

figure s4

7

Kalle2024

10.1021/acs.cgd.4c01197

1

Paulina Kalle, Stanislav I. Bezzubov, Lyudmila G. Kuzmina, Andrei V. Churakov

New Insights into the Structure, Thermal Properties, and Photostability of Industrially Relevant Salts of Sorbic Acid

Crystal Growth & Design

2,024

9,173

0

NH4Sorb·HSorb

manuscript

text

2

null

Sorbic Acid

manuscript

text

1

C/C=C/C=C/C(=O)O

null

Ammonium

manuscript

text

2

[NH4+]

manuscript

text

2

decreases

supporting information

figure s5

8

Geng2013

10.1021/cg400518w

1

Na Geng, Jia-Mei Chen, Zi-Jian Li, Long Jiang, Tong-Bu Lu

Approach of cocrystallization to improve the solubility and photostability of tranilast

Crystal Growth & Design

2,013

3,546

0

1

manuscript

text

3

1:1

manuscript

text

3

Tranilast

manuscript

text

1

COc1ccc(C=CC(=O)Nc2ccccc2C(=O)O)cc1OC

manuscript

figure 1

2

Urea

manuscript

text

1

NC(N)=O

manuscript

figure 1

2

increases

manuscript

figure 8

7

Geng2013

10.1021/cg400518w

1

Na Geng, Jia-Mei Chen, Zi-Jian Li, Long Jiang, Tong-Bu Lu

Approach of cocrystallization to improve the solubility and photostability of tranilast

Crystal Growth & Design

2,013

3,546

0

2

manuscript

text

3

1:1

manuscript

text

3

Tranilast

manuscript

text

1

COc1ccc(C=CC(=O)Nc2ccccc2C(=O)O)cc1OC

manuscript

figure 1

2

Nicotinamide

manuscript

text

1

NC(=O)c1cccnc1

manuscript

figure 1

2

increases

manuscript

figure 8

7

Geng2013

10.1021/cg400518w

1

Na Geng, Jia-Mei Chen, Zi-Jian Li, Long Jiang, Tong-Bu Lu

Approach of cocrystallization to improve the solubility and photostability of tranilast

Crystal Growth & Design

2,013

3,546

0

3

manuscript

text

3

1:1

manuscript

text

3

Tranilast

manuscript

text

1

COc1ccc(C=CC(=O)Nc2ccccc2C(=O)O)cc1OC

manuscript

figure 1

2

Cytosine

manuscript

text

1

Nc1cc[nH]c(=O)n1

manuscript

figure 1

2

increases

manuscript

figure 8

7

Geng2013

10.1021/cg400518w

1

Na Geng, Jia-Mei Chen, Zi-Jian Li, Long Jiang, Tong-Bu Lu

Approach of cocrystallization to improve the solubility and photostability of tranilast

Crystal Growth & Design

2,013

3,546

0

4

manuscript

text

3

null

Tranilast

manuscript

text

1

COc1ccc(C=CC(=O)Nc2ccccc2C(=O)O)cc1OC

manuscript

figure 1

2

Sodium

manuscript

text

1

null

increases

manuscript

figure 8

7

bofill2021

10.1021/acs.cgd.0c01709

1

Lídia Bofill, Dafne de Sande, Rafael Barbas, Rafel Prohens

A New and Highly Stable Cocrystal of Vitamin D3 for Use in Enhanced Food Supplements

Crystal Growth & Design

2,021

1,418

0

Vitamin D3−Resorcinol cocrystal

manuscript

text

2

1:1

supporting information

text

2

cholecalciferol

manuscript

text

1

C=C1CC[C@H](O)C/C1=C/C=C1\CCC[C@]2(C)[C@@H]([C@H](C)CCCC(C)C)CC[C@@H]12

manuscript

figure 1

3

resorcinol

manuscript

text

1

Oc1cccc(O)c1

manuscript

figure 1

3

increases

manuscript

figure 3

4

zhu2016

10.1021/acs.cgd.5b01491

1

Bingqing Zhu, Jian-Rong Wang, Qi Zhang, Xuefeng Mei

Improving Dissolution and Photostability of Vitamin K3 via Cocrystallization with Naphthoic Acids and Sulfamerazine

Crystal Growth & Design

2,015

483

0

MD·1-HNA

manuscript

text

4

null

Menadione

manuscript

text

1

CC1=CC(=O)c2ccccc2C1=O

manuscript

scheme 1

1

1-Hydroxy-2-naphthoic Acid

manuscript

text

2

O=C(O)c1ccc2ccccc2c1O

manuscript

scheme 2

2

increases

manuscript

figure 12

9

zhu2016

10.1021/acs.cgd.5b01491

1

Bingqing Zhu, Jian-Rong Wang, Qi Zhang, Xuefeng Mei

Improving Dissolution and Photostability of Vitamin K3 via Cocrystallization with Naphthoic Acids and Sulfamerazine

Crystal Growth & Design

2,015

483

0

MD·6-HNA

manuscript

text

4

null

Menadione

manuscript

text

1

CC1=CC(=O)c2ccccc2C1=O

manuscript

scheme 1

1

6-Hydroxy-2-naphthoic Acid

manuscript

text

2

O=C(O)c1ccc2cc(O)ccc2c1

manuscript

scheme 2

2

increases

supporting information

figure S8a

11

zhu2016

10.1021/acs.cgd.5b01491

1

Bingqing Zhu, Jian-Rong Wang, Qi Zhang, Xuefeng Mei

Improving Dissolution and Photostability of Vitamin K3 via Cocrystallization with Naphthoic Acids and Sulfamerazine

Crystal Growth & Design

2,015

483

0

MD·Sul

manuscript

text

4

null

Menadione

manuscript

text

1

CC1=CC(=O)c2ccccc2C1=O

manuscript

scheme 1

1

Sulfamerazine

manuscript

text

2

Cc1ccnc(NS(=O)(=O)c2ccc(N)cc2)n1

manuscript

scheme 2

2

increases

supporting information

figure S8b

11

Datasets:

ai-chem
/

Co-crystals

Collection including ai-chem/Co-crystals

ChemX