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2184
10594393
[ { "id": "2185", "type": "document", "text": [ "Ursodeoxycholic acid has no influence on function after restorative proctocolectomy in ulcerative colitis . BACKGROUND Poor pouch function is associated with impaired bile acid absorption and increased faecal loss of bile acids . Bile acid replacement...
[ { "id": "2186", "type": "Intervention_Pharmacological", "text": [ "Ursodeoxycholic acid" ], "offsets": [ [ 0, 20 ] ], "normalized": [] }, { "id": "2187", "type": "Intervention_Pharmacological", "text": [ "Bile acid replacement thera...
[]
[]
[]
2202
10594396
[ { "id": "2203", "type": "document", "text": [ "Standard-dose lansoprazole is more effective than high-dose ranitidine in achieving endoscopic healing and symptom relief in patients with moderately severe reflux oesophagitis . The Dutch Lansoprazole Study Group . BACKGROUND In the treatment of refl...
[ { "id": "2204", "type": "Intervention_Pharmacological", "text": [ "Standard-dose lansoprazole" ], "offsets": [ [ 0, 26 ] ], "normalized": [] }, { "id": "2205", "type": "Intervention_Pharmacological", "text": [ "high-dose ranitidine"...
[]
[]
[]
2226
10599355
[ { "id": "2227", "type": "document", "text": [ "Enalapril ( 10 mg/day ) in systemic sclerosis . One year , double blind , randomised study ( ESS-1 ) : echocardiographic substudy -- three months follow-up . The ESS-1 study was designed to evaluate the long-term effects of the angiotensin converting ...
[ { "id": "2228", "type": "Intervention_Pharmacological", "text": [ "Enalapril" ], "offsets": [ [ 0, 9 ] ], "normalized": [] }, { "id": "2229", "type": "Intervention_Pharmacological", "text": [ "enalapril" ], "offsets": [ ...
[]
[]
[]
2241
10602739
[ { "id": "2242", "type": "document", "text": [ "Ciprofloxacin , lomefloxacin , or levofloxacin as treatment for chronic osteomyelitis . The efficacy and safety of three oral fluoroquinolones ( lomefloxacin , levofloxacin , and ciprofloxacin ) for the treatment of chronic osteomyelitis were analyzed...
[ { "id": "2243", "type": "Intervention_Pharmacological", "text": [ "Ciprofloxacin" ], "offsets": [ [ 0, 13 ] ], "normalized": [] }, { "id": "2244", "type": "Intervention_Pharmacological", "text": [ "lomefloxacin" ], "offsets"...
[]
[]
[]
2262
10606880
[ { "id": "2263", "type": "document", "text": [ "Partial depletion of tissue factor pathway inhibitor during subcutaneous administration of unfractionated heparin , but not with two low molecular weight heparins . Tissue factor pathway inhibitor ( TFPI ) is released to circulating blood after intrav...
[ { "id": "2264", "type": "Intervention_Pharmacological", "text": [ "heparin" ], "offsets": [ [ 106, 113 ] ], "normalized": [] }, { "id": "2265", "type": "Intervention_Pharmacological", "text": [ "unfractionated heparin" ], "o...
[]
[]
[]
2285
10607234
[ { "id": "2286", "type": "document", "text": [ "Quantitative monitoring of serum hepatitis B virus DNA and blood lymphocyte subsets during combined prednisolone and interferon-alpha therapy in patients with chronic hepatitis B . Several investigators have reported a significantly reduced CD4/CD8 ra...
[ { "id": "2287", "type": "Intervention_Pharmacological", "text": [ "combined prednisolone" ], "offsets": [ [ 91, 112 ] ], "normalized": [] }, { "id": "2288", "type": "Intervention_Pharmacological", "text": [ "interferon-alpha therapy...
[]
[]
[]
2304
10618526
[ { "id": "2305", "type": "document", "text": [ "Early immunisation with hepatitis B vaccine : a five-year study . We evaluated the response to the recombinant Hepatitis B vaccine using an accelerated schedule versus the traditional schedule by studying the immunologic memory induced in 200 children...
[ { "id": "2306", "type": "Intervention_Pharmacological", "text": [ "hepatitis B vaccine :" ], "offsets": [ [ 24, 45 ] ], "normalized": [] }, { "id": "2307", "type": "Intervention_Pharmacological", "text": [ "recombinant Hepatitis B v...
[]
[]
[]
2315
10619912
[ { "id": "2316", "type": "document", "text": [ "Gastric carcinoma : expression of c-erbB-2/neu oncoprotein , epidermal growth factor receptor , cathepsin D , progesterone receptor and tumor associated glycoprotein-72 in different histological types . OBJECTIVE Gastric carcinoma can be divided into ...
[ { "id": "2317", "type": "Intervention_Pharmacological", "text": [ "neu/c-erbB-2 oncoprotein" ], "offsets": [ [ 378, 402 ] ], "normalized": [] }, { "id": "2318", "type": "Intervention_Physical", "text": [ "ELISA" ], "offsets"...
[]
[]
[]
2352
10624759
[ { "id": "2353", "type": "document", "text": [ "Prediction of metabolic and cardiopulmonary responses to maximum cycle ergometry : a randomised study . All of the most widely-cited studies for the prediction of maximum exercise responses have utilized either volunteers or referred subjects . Theref...
[ { "id": "2354", "type": "Intervention_Physical", "text": [ "maximum cycle ergometry" ], "offsets": [ [ 57, 80 ] ], "normalized": [] }, { "id": "2355", "type": "Intervention_Physical", "text": [ "maximum ramp-incremental cycle ergome...
[]
[]
[]
2373
10632537
[ { "id": "2374", "type": "document", "text": [ "Focal therapeutic efficacy of transcatheter arterial infusion of styrene maleic acid neocarzinostatin for hepatocellular carcinoma . We evaluated the focal therapeutic effect of oily carcinostatic agents administered by transcatheter arterial infusion...
[ { "id": "2375", "type": "Intervention_Pharmacological", "text": [ "styrene maleic acid" ], "offsets": [ [ 65, 84 ] ], "normalized": [] }, { "id": "2376", "type": "Intervention_Pharmacological", "text": [ "oily carcinostatic agents" ...
[]
[]
[]
2397
10634835
[ { "id": "2398", "type": "document", "text": [ "Randomised controlled trial of patient triggered and conventional fast rate ventilation in neonatal respiratory distress syndrome . AIM To compare patient triggered , with conventional fast rate , ventilation in a randomised controlled trial using the...
[ { "id": "2399", "type": "Intervention_Physical", "text": [ "conventional fast rate ventilation" ], "offsets": [ [ 53, 87 ] ], "normalized": [] }, { "id": "2400", "type": "Intervention_Pharmacological", "text": [ "trigger ventilation...
[]
[]
[]
2407
10634838
[ { "id": "2408", "type": "document", "text": [ "Randomised controlled study of clinical outcome following trophic feeding . AIMS To determine the effect of trophic feeding on clinical outcome in ill preterm infants . METHODS A randomised , controlled , prospective study of 100 preterm infants , wei...
[ { "id": "2409", "type": "Intervention_Pharmacological", "text": [ "trophic feeding ." ], "offsets": [ [ 58, 75 ] ], "normalized": [] }, { "id": "2410", "type": "Intervention_Pharmacological", "text": [ "trophic feeding" ], "...
[]
[]
[]
2435
10636373
[ { "id": "2436", "type": "document", "text": [ "Treatment of hypertension with ascorbic acid . In a randomised , double-blind , placebo-controlled study we showed that treatment of hypertensive patients with ascorbic acid lowers blood pressure . Further studies of ascorbic acid to treat hypertensio...
[ { "id": "2437", "type": "Intervention_Pharmacological", "text": [ "ascorbic acid" ], "offsets": [ [ 31, 44 ] ], "normalized": [] }, { "id": "2438", "type": "Intervention_Control", "text": [ "placebo-controlled" ], "offsets":...
[]
[]
[]
2446
10637238
[ { "id": "2447", "type": "document", "text": [ "Comparison of chemotherapy with chemohormonal therapy as first-line therapy for metastatic , hormone-sensitive breast cancer : An Eastern Cooperative Oncology Group study . PURPOSE Although hormonal therapy represents standard therapy for metastatic h...
[ { "id": "2448", "type": "Intervention_Pharmacological", "text": [ "chemotherapy" ], "offsets": [ [ 14, 26 ] ], "normalized": [] }, { "id": "2449", "type": "Intervention_Pharmacological", "text": [ "chemohormonal therapy" ], ...
[]
[]
[]
2458
10643677
[ { "id": "2459", "type": "document", "text": [ "The effect of body weight changes and endurance training on 24h substrate oxidation . OBJECTIVE To investigate the effect of exercise training and dietary macronutrient composition on 24 h substrate oxidation in male , obese subjects . DESIGN A 16 mon...
[ { "id": "2460", "type": "Intervention_Other", "text": [ "exercise training and" ], "offsets": [ [ 125, 146 ] ], "normalized": [] }, { "id": "2461", "type": "Intervention_Educational", "text": [ "dietary macronutrient composition" ...
[]
[]
[]
2489
10649829
[ { "id": "2490", "type": "document", "text": [ "The relationship between repetitive behaviors and growth hormone response to sumatriptan challenge in adult autistic disorder . Autism is heterogeneous with respect to clinical symptoms and etiology . To sort out this heterogeneity in autism , we inve...
[ { "id": "2491", "type": "Intervention_Pharmacological", "text": [ "sumatriptan" ], "offsets": [ [ 77, 88 ] ], "normalized": [] }, { "id": "2492", "type": "Intervention_Pharmacological", "text": [ "5-HT 1d agonist , sumatriptan" ...
[]
[]
[]
2524
10651597
[ { "id": "2525", "type": "document", "text": [ "Effectiveness of manual physical therapy and exercise in osteoarthritis of the knee . A randomized , controlled trial . BACKGROUND Few investigations include both subjective and objective measurements of the effectiveness of treatments for osteoarthri...
[ { "id": "2526", "type": "Intervention_Physical", "text": [ "manual physical therapy and exercise" ], "offsets": [ [ 17, 53 ] ], "normalized": [] }, { "id": "2527", "type": "Intervention_Physical", "text": [ "physical therapy" ],...
[]
[]
[]
2574
10660161
[ { "id": "2575", "type": "document", "text": [ "Regression of left ventricular hypertrophy after stentless versus conventional aortic valve replacement . The goal of this study was to analyze regression of left ventricular hypertrophy after randomization to conventional biological versus stentless ...
[ { "id": "2576", "type": "Intervention_Physical", "text": [ "stentless" ], "offsets": [ [ 49, 58 ] ], "normalized": [] }, { "id": "2577", "type": "Intervention_Surgical", "text": [ "conventional aortic valve replacement" ], "...
[]
[]
[]
2590
10661479
[ { "id": "2591", "type": "document", "text": [ "Changes in cardiac muscle mass and function in hemodialysis patients during growth hormone treatment . BACKGROUND Adult patients with chronic renal failure ( CRF ) often show symptoms as fatigue , wasting , and reduced working capacity with concomitan...
[ { "id": "2592", "type": "Intervention_Pharmacological", "text": [ "growth hormone treatment" ], "offsets": [ [ 76, 100 ] ], "normalized": [] }, { "id": "2593", "type": "Intervention_Pharmacological", "text": [ "exogenous growth horm...
[]
[]
[]
2618
10663363
[ { "id": "2619", "type": "document", "text": [ "Randomized trial of the effects of risedronate on vertebral fractures in women with established postmenopausal osteoporosis . Vertebral Efficacy with Risedronate Therapy ( VERT ) Study Group . The purpose of this randomized , double-masked , placebo-c...
[ { "id": "2620", "type": "Intervention_Pharmacological", "text": [ "risedronate" ], "offsets": [ [ 35, 46 ] ], "normalized": [] }, { "id": "2621", "type": "Intervention_Pharmacological", "text": [ "risedronate" ], "offsets": ...
[]
[]
[]
2646
10665129
[ { "id": "2647", "type": "document", "text": [ "Bronchodilatory responses to formoterol , ipratropium , and their combination in patients with stable COPD . We studied 27 patients with stable chronic obstuctive pulmonary disease ( COPD ) in a randomised , single-blind , within-patient , placebo-con...
[ { "id": "2648", "type": "Intervention_Pharmacological", "text": [ "formoterol" ], "offsets": [ [ 29, 39 ] ], "normalized": [] }, { "id": "2649", "type": "Intervention_Pharmacological", "text": [ "ipratropium" ], "offsets": [...
[]
[]
[]
2670
10671339
[ { "id": "2671", "type": "document", "text": [ "Granulocyte-macrophage colony-stimulating factor as immunomodulating factor together with influenza vaccination in stem cell transplant patients . The effect of granulocyte-macrophage colony-stimulating factor ( GM-CSF ) on the serological response at...
[ { "id": "2672", "type": "Intervention_Pharmacological", "text": [ "Granulocyte-macrophage colony-stimulating factor" ], "offsets": [ [ 0, 48 ] ], "normalized": [] }, { "id": "2673", "type": "Intervention_Pharmacological", "text": [ ...
[]
[]
[]
2692
10674229
[ { "id": "2693", "type": "document", "text": [ "Differential effects of amino acid and ketoacid on protein metabolism in humans . We examined the effects of insulin , amino acid ( AA ) , and branched-chain ketoacid ( KA ) availability on leucine kinetics in eight healthy volunteers ( age = 22 +/- 2...
[ { "id": "2694", "type": "Intervention_Other", "text": [ "euglycemic insulin clamp" ], "offsets": [ [ 301, 325 ] ], "normalized": [] }, { "id": "2695", "type": "Intervention_Physical", "text": [ "and [ 1-14C ]" ], "offsets": ...
[]
[]
[]
2709
10674680
[ { "id": "2710", "type": "document", "text": [ "Assessment of therapeutic response of Plasmodium falciparum to chloroquine and sulfadoxine-pyrimethamine in an area of low malaria transmission in Colombia . Although chloroquine ( CQ ) resistance was first reported in Colombia in 1961 and sulfadoxine...
[ { "id": "2711", "type": "Intervention_Pharmacological", "text": [ "chloroquine" ], "offsets": [ [ 63, 74 ] ], "normalized": [] }, { "id": "2712", "type": "Intervention_Pharmacological", "text": [ "sulfadoxine-pyrimethamine" ], ...
[]
[]
[]
2733
10674681
[ { "id": "2734", "type": "document", "text": [ "Efficacy of primaquine regimens for primaquine-resistant Plasmodium vivax malaria in Thailand . To define the current efficacy of Fansidar ( F. Hoffmann-La Roche Ltd. , Basel Switzerland ) ( pyrimethamine and sulfadoxine ) , primaquine in a high dose ...
[ { "id": "2735", "type": "Intervention_Pharmacological", "text": [ "primaquine regimens" ], "offsets": [ [ 12, 31 ] ], "normalized": [] }, { "id": "2736", "type": "Intervention_Pharmacological", "text": [ "Fansidar" ], "offse...
[]
[]
[]
2757
10678548
[ { "id": "2758", "type": "document", "text": [ "Safety of the combination of valsartan and benazepril in patients with chronic renal disease . European Group for the Investigation of Valsartan in Chronic Renal Disease . OBJECTIVE Several experimental and clinical studies indicate that the renin sys...
[ { "id": "2759", "type": "Intervention_Pharmacological", "text": [ "combination of valsartan" ], "offsets": [ [ 14, 38 ] ], "normalized": [] }, { "id": "2760", "type": "Intervention_Pharmacological", "text": [ "benazepril" ], ...
[]
[]
[]
2790
10682031
[ { "id": "2791", "type": "document", "text": [ "[ Administration of tobramycin aerosols in patients with nosocomial pneumonia : a preliminary study ] . OBJECTIVE The aim of this study was to assess renal and respiratory tolerance of aerosolized tobramycin in intubated and mechanically ventilated pa...
[ { "id": "2792", "type": "Intervention_Pharmacological", "text": [ "tobramycin aerosols" ], "offsets": [ [ 20, 39 ] ], "normalized": [] }, { "id": "2793", "type": "Intervention_Pharmacological", "text": [ "tobramycin" ], "off...
[]
[]
[]
2809
10683506
[ { "id": "2810", "type": "document", "text": [ "Effect of sensory stimulation ( acupuncture ) on sympathetic and parasympathetic activities in healthy subjects . UNLABELLED It has been postulated that sensory stimulation ( acupuncture ) affects the cardiovascular system via the autonomic nervous sy...
[ { "id": "2811", "type": "Intervention_Physical", "text": [ "sensory stimulation" ], "offsets": [ [ 10, 29 ] ], "normalized": [] }, { "id": "2812", "type": "Intervention_Physical", "text": [ "sensory stimulation ( acupuncture )" ...
[]
[]
[]
2836
10685169
[ { "id": "2837", "type": "document", "text": [ "Effect of topical rh-TGF-beta 1 on second intention wound healing in horses . OBJECTIVE To investigate the effects on wound healing of transforming growth factor-beta 1 as a topical treatment to full-thickness , excisional wounds of the distal limb of...
[ { "id": "2838", "type": "Intervention_Pharmacological", "text": [ "rh-TGF-beta 1" ], "offsets": [ [ 18, 31 ] ], "normalized": [] }, { "id": "2839", "type": "Intervention_Pharmacological", "text": [ "growth factor-beta 1" ], ...
[]
[]
[]
2854
10685722
[ { "id": "2855", "type": "document", "text": [ "Efficacy and safety of a fixed low-dose perindopril/indapamide combination in essential hypertension . A randomised controlled study . This multicenter , double-blind , parallel-group study was designed to assess the efficacy and the safety of fixed l...
[ { "id": "2856", "type": "Intervention_Pharmacological", "text": [ "perindopril/indapamide combination" ], "offsets": [ [ 40, 74 ] ], "normalized": [] }, { "id": "2857", "type": "Intervention_Pharmacological", "text": [ "low dose com...
[]
[]
[]
2878
10685817
[ { "id": "2879", "type": "document", "text": [ "Treatment of whiplash associated neck pain [ corrected ] with botulinum toxin-A : a pilot study . OBJECTIVE Up to 87 % of patients with whiplash associated disorder ( WAD ) have some degree of muscle spasm that is contributory to both pain and dysfunc...
[ { "id": "2880", "type": "Intervention_Pharmacological", "text": [ "botulinum toxin-A :" ], "offsets": [ [ 62, 81 ] ], "normalized": [] }, { "id": "2881", "type": "Intervention_Pharmacological", "text": [ "Botulinum toxin A ( BTX-A )...
[]
[]
[]
2901
10690138
[ { "id": "2902", "type": "document", "text": [ "Comparison of 0.25 % S ( - ) -bupivacaine with 0.25 % RS-bupivacaine for epidural analgesia in labour . We have compared the efficacy of 0.25 % S ( - ) -bupivacaine with 0.25 % RS-bupivacaine in providing epidural analgesia for labour in a randomized ...
[ { "id": "2903", "type": "Intervention_Pharmacological", "text": [ "S ( - ) -bupivacaine" ], "offsets": [ [ 21, 41 ] ], "normalized": [] }, { "id": "2904", "type": "Intervention_Pharmacological", "text": [ "RS-bupivacaine" ], ...
[]
[]
[]
2917
10690697
[ { "id": "2918", "type": "document", "text": [ "Hip protectors improve falls self-efficacy . OBJECTIVES To investigate the effect of use of external hip protectors on subjects ' fear of falling and falls self-efficacy ( belief in their own ability to avoid falling ) . DESIGN Randomized controlled t...
[ { "id": "2919", "type": "Intervention_Physical", "text": [ "Hip protectors" ], "offsets": [ [ 0, 14 ] ], "normalized": [] }, { "id": "2920", "type": "Intervention_Physical", "text": [ "external hip protectors" ], "offsets": ...
[]
[]
[]
2948
10693733
[ { "id": "2949", "type": "document", "text": [ "Sun protection counseling for children : primary care practice patterns and effect of an intervention on clinicians . OBJECTIVES To describe current primary care sun protection advice for children and assess the effect on clinicians of an intervention...
[ { "id": "2950", "type": "Intervention_Educational", "text": [ "Sun protection counseling for children :" ], "offsets": [ [ 0, 40 ] ], "normalized": [] }, { "id": "2951", "type": "Intervention_Educational", "text": [ "primary care su...
[]
[]
[]
2967
10703628
[ { "id": "2968", "type": "document", "text": [ "Efficacy of a barrier cream and its vehicle as protective measures against occupational irritant contact dermatitis . The actual advantage of barrier creams over bland emollients for skin protection is still hotly debated . In a randomized , double-bl...
[ { "id": "2969", "type": "Intervention_Physical", "text": [ "barrier cream" ], "offsets": [ [ 14, 27 ] ], "normalized": [] }, { "id": "2970", "type": "Intervention_Physical", "text": [ "its vehicle" ], "offsets": [ [ ...
[]
[]
[]
2989
10706930
[ { "id": "2990", "type": "document", "text": [ "The effects of hormone replacement therapy on hemostatic variables in women with angiographically verified coronary artery disease : results from the estrogen in women with atherosclerosis study . Data on the effect of hormone replacement therapy on h...
[ { "id": "2991", "type": "Intervention_Physical", "text": [ "hormone replacement therapy" ], "offsets": [ [ 15, 42 ] ], "normalized": [] }, { "id": "2992", "type": "Intervention_Pharmacological", "text": [ "hormone replacement therap...
[]
[]
[]
3016
10707032
[ { "id": "3017", "type": "document", "text": [ "Treatment with metformin of non-diabetic men with hypertension , hypertriglyceridaemia and central fat distribution : the BIGPRO 1.2 trial . BACKGROUND In the BIGPRO 1 trial , one year of treatment with metformin in non-diabetic obese subjects with a ...
[ { "id": "3018", "type": "Intervention_Pharmacological", "text": [ "metformin" ], "offsets": [ [ 15, 24 ] ], "normalized": [] }, { "id": "3019", "type": "Intervention_Pharmacological", "text": [ "metformin" ], "offsets": [ ...
[]
[]
[]
3044
10715372
[ { "id": "3045", "type": "document", "text": [ "Study of the vaginal tolerance to Acidform , an acid-buffering , bioadhesive gel . Vaginal tolerance tests were performed with a new potential microbicidal and spermicidal product , an acid-buffering vaginal gel ( Acidform ) without or with nonoxynol-...
[ { "id": "3046", "type": "Intervention_Pharmacological", "text": [ "Acidform" ], "offsets": [ [ 34, 42 ] ], "normalized": [] }, { "id": "3047", "type": "Intervention_Pharmacological", "text": [ "acid-buffering" ], "offsets": ...
[]
[]
[]
3063
10719133
[ { "id": "3064", "type": "document", "text": [ "Blood pressure biofeedback treatment of white-coat hypertension . OBJECTIVE The objective of the study was to compare blood pressure ( BP ) biofeedback treatment ( BF ) effects between white-coat hypertension and essential hypertension . METHODS Fifte...
[ { "id": "3065", "type": "Intervention_Psychological", "text": [ "Blood pressure biofeedback treatment" ], "offsets": [ [ 0, 36 ] ], "normalized": [] }, { "id": "3066", "type": "Intervention_Psychological", "text": [ "biofeedback tre...
[]
[]
[]
3084
10720081
[ { "id": "3085", "type": "document", "text": [ "Growth hormone ( GH ) responses to GH-releasing hormone alone or combined with arginine in patients with adrenal incidentaloma : evidence for enhanced somatostatinergic tone . Spontaneous and stimulated GH secretion is blunted in hypercortisolemic sta...
[ { "id": "3086", "type": "Intervention_Physical", "text": [ "GH-releasing hormone alone" ], "offsets": [ [ 35, 61 ] ], "normalized": [] }, { "id": "3087", "type": "Intervention_Physical", "text": [ "combined with arginine" ], ...
[]
[]
[]
3125
10726430
[ { "id": "3126", "type": "document", "text": [ "Evaluating a test protocol for predicting maximum lactate steady state . BACKGROUND Maximum lactate steady state ( MLSS ) is defined as the highest steady state exercise level one can maintain while also maintaining an equilibrium between the eliminat...
[ { "id": "3127", "type": "Intervention_Physical", "text": [ "Lactate Minimum Test ( LMT )" ], "offsets": [ [ 499, 527 ] ], "normalized": [] }, { "id": "3128", "type": "Outcome_Physical", "text": [ "maximum lactate steady state ." ...
[]
[]
[]
3136
10734271
[ { "id": "3137", "type": "document", "text": [ "Computer-assisted instruction : an effective instructional method for HIV prevention education ? PURPOSE To compare the effectiveness of a computer-assisted instruction ( CAI ) -based intervention to a more traditional lecture-based intervention for i...
[ { "id": "3138", "type": "Intervention_Educational", "text": [ "Computer-assisted instruction" ], "offsets": [ [ 0, 29 ] ], "normalized": [] }, { "id": "3139", "type": "Intervention_Educational", "text": [ "computer-assisted instruct...
[]
[]
[]
3155
10735838
[ { "id": "3156", "type": "document", "text": [ "A comparison of local anaesthetics for venepuncture . AIM To compare the effectiveness of EMLA cream and Ametop gel in providing analgesia for venous cannulation . METHODS Single blind study in 120 children . RESULTS Both anaesthetic agents produced a...
[ { "id": "3157", "type": "Intervention_Physical", "text": [ "local anaesthetics" ], "offsets": [ [ 16, 34 ] ], "normalized": [] }, { "id": "3158", "type": "Intervention_Pharmacological", "text": [ "EMLA cream" ], "offsets": [...
[]
[]
[]
3167
10735900
[ { "id": "3168", "type": "document", "text": [ "Use of recombinant human granulocyte colony-stimulating factor to increase chemotherapy dose-intensity : a randomized trial in very high-risk childhood acute lymphoblastic leukemia . PURPOSE To determine whether the use of a recombinant human granuloc...
[ { "id": "3169", "type": "Intervention_Physical", "text": [ "recombinant human granulocyte colony-stimulating factor" ], "offsets": [ [ 7, 62 ] ], "normalized": [] }, { "id": "3170", "type": "Intervention_Physical", "text": [ "chemot...
[]
[]
[]
3206
10741095
[ { "id": "3207", "type": "document", "text": [ "Comparison of different long-term asthma treatments in subjects with mild-to-moderate asthma . In order to compare the efficacy of different asthma treatment in subjects with mild-to-moderate asthma , three groups of 11 patients were treated with nedo...
[ { "id": "3208", "type": "Intervention_Pharmacological", "text": [ "nedocromil sodium ( NS )" ], "offsets": [ [ 247, 271 ] ], "normalized": [] }, { "id": "3209", "type": "Intervention_Pharmacological", "text": [ "beclomethasone dipro...
[]
[]
[]
3225
10741842
[ { "id": "3226", "type": "document", "text": [ "Asthma and the home environment of low-income urban children : preliminary findings from the Seattle-King County healthy homes project . OBJECTIVES Childhood asthma is a growing public health concern in low-income urban communities . Indoor exposure t...
[ { "id": "3227", "type": "Intervention_Other", "text": [ "intervention" ], "offsets": [ [ 979, 991 ] ], "normalized": [] }, { "id": "3228", "type": "Outcome_Other", "text": [ "Mold was visible" ], "offsets": [ [ ...
[]
[]
[]
3244
10742359
[ { "id": "3245", "type": "document", "text": [ "Impact of an encounter-based prompting system on resident vaccine administration performance and immunization knowledge . OBJECTIVES To evaluate an encounter-based immunization prompting system on resident performance in administering vaccines and kno...
[ { "id": "3246", "type": "Intervention_Educational", "text": [ "encounter-based prompting system" ], "offsets": [ [ 13, 45 ] ], "normalized": [] }, { "id": "3247", "type": "Intervention_Educational", "text": [ "encounter-based immuni...
[]
[]
[]
3256
10754477
[ { "id": "3257", "type": "document", "text": [ "The GH response to low-dose bolus growth hormone-releasing hormone ( GHRH ( 1-29 ) NH2 ) is attenuated in patients with longstanding post-irradiation GH insufficiency . OBJECTIVE Previous studies have suggested that post-irradiation GH insufficiency r...
[ { "id": "3258", "type": "Intervention_Pharmacological", "text": [ "low-dose bolus growth hormone-releasing hormone ( GHRH ( 1-29 ) NH2 )" ], "offsets": [ [ 19, 88 ] ], "normalized": [] }, { "id": "3259", "type": "Intervention_Pharmacological"...
[]
[]
[]
3280
10755175
[ { "id": "3281", "type": "document", "text": [ "Auditory integration training for children with autism : no behavioral benefits detected . Auditory integration training and a control treatment were provided for 16 children with autism in a crossover experimental design . Measures , blind to treatme...
[ { "id": "3282", "type": "Intervention_Educational", "text": [ "Auditory integration training" ], "offsets": [ [ 0, 29 ] ], "normalized": [] }, { "id": "3283", "type": "Intervention_Educational", "text": [ "Auditory integration train...
[]
[]
[]
3307
10757250
[ { "id": "3308", "type": "document", "text": [ "Antisaccade and smooth pursuit eye movements in healthy subjects receiving sertraline and lorazepam . Patients suffering from some psychiatric and neurological disorders demonstrate abnormally high levels of saccadic distractibility when carrying out ...
[ { "id": "3309", "type": "Intervention_Pharmacological", "text": [ "sertraline" ], "offsets": [ [ 75, 85 ] ], "normalized": [] }, { "id": "3310", "type": "Intervention_Pharmacological", "text": [ "lorazepam" ], "offsets": [ ...
[]
[]
[]
3324
10757579
[ { "id": "3325", "type": "document", "text": [ "Ropivacaine-clonidine combination for caudal blockade in children . BACKGROUND Adding clonidine to weak ropivacaine solutions ( < 0.2 % ) could potentially enhance analgesia as well as further reduce the risk for unwanted motor blockade . The aim of t...
[ { "id": "3326", "type": "Intervention_Pharmacological", "text": [ "Ropivacaine-clonidine combination" ], "offsets": [ [ 0, 33 ] ], "normalized": [] }, { "id": "3327", "type": "Intervention_Pharmacological", "text": [ "clonidine" ...
[]
[]
[]
3352
10758987
[ { "id": "3353", "type": "document", "text": [ "American College of Cardiology/European Society of Cardiology International Study of Angiographic Data Compression Phase I : The effect of lossy data compression on recognition of diagnostic features in digital coronary angiography . OBJECTIVES This s...
[ { "id": "3354", "type": "Intervention_Physical", "text": [ "data compression" ], "offsets": [ [ 145, 161 ] ], "normalized": [] }, { "id": "3355", "type": "Intervention_Physical", "text": [ "digital coronary angiography" ], "...
[]
[]
[]
3370
10759619
[ { "id": "3371", "type": "document", "text": [ "Pharmacokinetic interaction between proton pump inhibitors and roxithromycin in volunteers . BACKGROUND Triple therapy including two antibiotics and a proton pump inhibitor is a rational approach to the treatment of Helicobacter pylori induced peptic ...
[ { "id": "3372", "type": "Intervention_Pharmacological", "text": [ "proton pump inhibitors" ], "offsets": [ [ 36, 58 ] ], "normalized": [] }, { "id": "3373", "type": "Intervention_Pharmacological", "text": [ "roxithromycin" ], ...
[]
[]
[]
3396
10768434
[ { "id": "3397", "type": "document", "text": [ "Photodynamic therapy with 5-aminolaevulinic acid or placebo for recalcitrant foot and hand warts : randomised double-blind trial . BACKGROUND Photodynamic therapy ( PDT ) with topical 5-aminolaevulinic acid ( ALA ) followed by irradiation with incoher...
[ { "id": "3398", "type": "Intervention_Control", "text": [ "Photodynamic therapy" ], "offsets": [ [ 0, 20 ] ], "normalized": [] }, { "id": "3399", "type": "Intervention_Pharmacological", "text": [ "5-aminolaevulinic acid" ], ...
[]
[]
[]
3425
10770301
[ { "id": "3426", "type": "document", "text": [ "Low molecular-weight heparin versus aspirin in patients with acute ischaemic stroke and atrial fibrillation : a double-blind randomised study . HAEST Study Group . Heparin in Acute Embolic Stroke Trial . BACKGROUND Patients with acute ischaemic stroke...
[ { "id": "3427", "type": "Intervention_Pharmacological", "text": [ "Low molecular-weight heparin" ], "offsets": [ [ 0, 28 ] ], "normalized": [] }, { "id": "3428", "type": "Intervention_Pharmacological", "text": [ "aspirin" ], ...
[]
[]
[]
3452
10770979
[ { "id": "3453", "type": "document", "text": [ "Lack of effect of a low-fat , high-fiber diet on the recurrence of colorectal adenomas . Polyp Prevention Trial Study Group . BACKGROUND We tested the hypothesis that dietary intervention can inhibit the development of recurrent colorectal adenomas , ...
[ { "id": "3454", "type": "Intervention_Physical", "text": [ "low-fat , high-fiber diet" ], "offsets": [ [ 20, 45 ] ], "normalized": [] }, { "id": "3455", "type": "Intervention_Educational", "text": [ "diet that was low in fat" ],...
[]
[]
[]
3472
10778276
[ { "id": "3473", "type": "document", "text": [ "Human motor responses to simultaneous aversive stimulation and failure on a valued task . The effects of presentation of an aversive stimulus and simultaneous failure on a bogus intelligence test upon a subject 's aggressive reactions were studied . T...
[ { "id": "3474", "type": "Intervention_Physical", "text": [ "aversive stimulation and failure" ], "offsets": [ [ 38, 70 ] ], "normalized": [] }, { "id": "3475", "type": "Intervention_Physical", "text": [ "aversive stimulus and simult...
[]
[]
[]
3485
10781855
[ { "id": "3486", "type": "document", "text": [ "Immunogenicity and reactogenicity of a group C meningococcal conjugate vaccine compared with a group A+C meningococcal polysaccharide vaccine in adolescents in a randomised observer-blind controlled trial . This study evaluated the immunogenicity and ...
[ { "id": "3487", "type": "Intervention_Pharmacological", "text": [ "group C meningococcal conjugate vaccine ( MenC ) compared with a group A+C meningococcal polysaccharide vaccine ( MenPS )" ], "offsets": [ [ 271, 392 ] ], "normalized": [] }, { "i...
[]
[]
[]
3498
10790473
[ { "id": "3499", "type": "document", "text": [ "Language , speech sound production , and cognition in three-year-old children in relation to otitis media in their first three years of life . OBJECTIVE As part of a prospective study of possible effects of early-life otitis media on speech , language...
[ { "id": "3500", "type": "Intervention_Physical", "text": [ "pneumatic otoscopy" ], "offsets": [ [ 777, 795 ] ], "normalized": [] }, { "id": "3501", "type": "Intervention_Physical", "text": [ "supplemented by tympanometry" ], ...
[]
[]
[]
3512
10807619
[ { "id": "3513", "type": "document", "text": [ "Randomised , double blind , placebo controlled study of fluticasone propionate in patients with moderate to severe chronic obstructive pulmonary disease : the ISOLDE trial . OBJECTIVES To determine the effect of long term inhaled corticosteroids on lu...
[ { "id": "3514", "type": "Intervention_Control", "text": [ "placebo" ], "offsets": [ [ 28, 35 ] ], "normalized": [] }, { "id": "3515", "type": "Intervention_Pharmacological", "text": [ "fluticasone propionate" ], "offsets": [...
[]
[]
[]
3541
10808042
[ { "id": "3542", "type": "document", "text": [ "Increased growth hormone response to sumatriptan challenge in adult autistic disorders . Serotonergic ( 5-HT ) abnormalities have been documented in autism . To assess sensitivity of the 5-HT1d receptor , growth hormone response to the 5-HT1d receptor...
[ { "id": "3543", "type": "Intervention_Pharmacological", "text": [ "sumatriptan" ], "offsets": [ [ 37, 48 ] ], "normalized": [] }, { "id": "3544", "type": "Intervention_Pharmacological", "text": [ "5-HT1d receptor agonist sumatriptan...
[]
[]
[]
3556
10811665
[ { "id": "3557", "type": "document", "text": [ "Outcome of CNS disease at diagnosis in disseminated small noncleaved-cell lymphoma and B-cell leukemia : a Children 's Cancer Group study . PURPOSE To examine the impact of initial CNS involvement on outcome and patterns of failure in patients with di...
[ { "id": "3558", "type": "Intervention_Other", "text": [ "Children 's Cancer Group trials" ], "offsets": [ [ 349, 380 ] ], "normalized": [] }, { "id": "3559", "type": "Intervention_Pharmacological", "text": [ "protocol-based systemic...
[]
[]
[]
3584
10816058
[ { "id": "3585", "type": "document", "text": [ "Heparin-coated cardiopulmonary bypass circuits reduce circulating complement factors and interleukin-6 in paediatric heart surgery . Children are sensitive to the inflammatory side effects of cardiopulmonary bypass ( CPB ) . Our intention was to inves...
[ { "id": "3586", "type": "Intervention_Physical", "text": [ "Heparin-coated cardiopulmonary bypass circuits" ], "offsets": [ [ 0, 46 ] ], "normalized": [] }, { "id": "3587", "type": "Intervention_Physical", "text": [ "heparin-coated ...
[]
[]
[]
3598
10817768
[ { "id": "3599", "type": "document", "text": [ "Does waiting matter ? A randomized controlled trial of new non-urgent rheumatology out-patient referrals . OBJECTIVE To examine the effect of waiting times on the health status of patients referred for a non-urgent rheumatology opinion . METHODS The s...
[ { "id": "3600", "type": "Intervention_Other", "text": [ "'fast track ' appointment with a 6-week target waiting time" ], "offsets": [ [ 312, 371 ] ], "normalized": [] }, { "id": "3601", "type": "Intervention_Control", "text": [ "'or...
[]
[]
[]
3611
10826576
[ { "id": "3612", "type": "document", "text": [ "Identifying the indications for laparoscopically assisted vaginal hysterectomy : a prospective , randomised comparison with abdominal hysterectomy in patients with symptomatic uterine fibroids . OBJECTIVE To compare laparoscopically assisted vaginal h...
[ { "id": "3613", "type": "Intervention_Surgical", "text": [ "laparoscopically assisted vaginal hysterectomy" ], "offsets": [ [ 32, 78 ] ], "normalized": [] }, { "id": "3614", "type": "Intervention_Physical", "text": [ "abdominal hyst...
[]
[]
[]
3653
10832772
[ { "id": "3654", "type": "document", "text": [ "Secretin and autism : a two-part clinical investigation . Recent anecdotal reports have touted the gastrointestinal ( GI ) hormone secretin as a treatment modality for autism , though there is little clinical evidence or literature to support its viab...
[ { "id": "3655", "type": "Intervention_Physical", "text": [ "secretin" ], "offsets": [ [ 131, 139 ] ], "normalized": [] }, { "id": "3656", "type": "Intervention_Physical", "text": [ "secretin" ], "offsets": [ [ ...
[]
[]
[]
3678
10832773
[ { "id": "3679", "type": "document", "text": [ "Comments on \" Secretin and autism : a two-part clinical investigation \" by M.G . Chez et al ." ], "offsets": [ [ 0, 93 ] ] } ]
[ { "id": "3680", "type": "Intervention_Pharmacological", "text": [ "Secretin" ], "offsets": [ [ 14, 22 ] ], "normalized": [] }, { "id": "3681", "type": "Outcome_Physical", "text": [ "Secretin" ], "offsets": [ [ ...
[]
[]
[]
3684
10832774
[ { "id": "3685", "type": "document", "text": [ "Assessment in multisite randomized clinical trials of patients with autistic disorder : the Autism RUPP Network . Research Units on Pediatric Psychopharmacology . Assessment of autistic disorder ( autism ) symptoms , primary and secondary , poses more...
[ { "id": "3686", "type": "Intervention_Pharmacological", "text": [ "risperidone RCT" ], "offsets": [ [ 687, 702 ] ], "normalized": [] }, { "id": "3687", "type": "Intervention_Pharmacological", "text": [ "risperidone" ], "offs...
[]
[]
[]
3702
10837440
[ { "id": "3703", "type": "document", "text": [ "Comparison of a 5 day regimen of cefdinir with a 10 day regimen of cefprozil for treatment of acute exacerbations of chronic bronchitis . Patients with acute exacerbations of chronic bronchitis were treated with cefdinir 300 mg bd for 5 days or cefpro...
[ { "id": "3704", "type": "Intervention_Pharmacological", "text": [ "cefdinir" ], "offsets": [ [ 33, 41 ] ], "normalized": [] }, { "id": "3705", "type": "Intervention_Pharmacological", "text": [ "cefprozil" ], "offsets": [ ...
[]
[]
[]
3730
10848655
[ { "id": "3731", "type": "document", "text": [ "The effectiveness of omeprazole , clarithromycin and tinidazole in eradicating Helicobacter pylori in a community screen and treat programme . Leeds Help Study Group . INTRODUCTION Helicobacter pylori screening and treatment has been proposed as a cos...
[ { "id": "3732", "type": "Intervention_Pharmacological", "text": [ "omeprazole" ], "offsets": [ [ 21, 31 ] ], "normalized": [] }, { "id": "3733", "type": "Intervention_Pharmacological", "text": [ "clarithromycin" ], "offsets"...
[]
[]
[]
3758
10850381
[ { "id": "3759", "type": "document", "text": [ "Reduction of oral mucositis by filgrastim ( r-metHuG-CSF ) in patients receiving chemotherapy . Mucositis , the inflammation and necrosis of mucosal membranes , is a serious and debilitating consequence of many cancer therapies . We were interested in...
[ { "id": "3760", "type": "Intervention_Pharmacological", "text": [ "filgrastim" ], "offsets": [ [ 31, 41 ] ], "normalized": [] }, { "id": "3761", "type": "Intervention_Pharmacological", "text": [ "r-metHuG-CSF" ], "offsets": ...
[]
[]
[]
3783
10860330
[ { "id": "3784", "type": "document", "text": [ "A laser-powered hydrokinetic system for caries removal and cavity preparation . BACKGROUND Laser systems have been developed for the cutting of dental hard tissues . The erbium , chromium : yttrium-scandium-gallium-garnet , or Er , Cr : YSGG , laser s...
[ { "id": "3785", "type": "Intervention_Surgical", "text": [ "Laser systems" ], "offsets": [ [ 91, 104 ] ], "normalized": [] }, { "id": "3786", "type": "Intervention_Surgical", "text": [ "Er , Cr : YSGG , laser system" ], "off...
[]
[]
[]
3800
10861653
[ { "id": "3801", "type": "document", "text": [ "Response of pre-core mutant chronic hepatitis B infection to lamivudine . The proportion of chronic liver disease associated with the pre-core mutant of hepatitis B virus ( HBV ) infection is increasing , particularly in Mediterranean Europe and in As...
[ { "id": "3802", "type": "Intervention_Pharmacological", "text": [ "lamivudine" ], "offsets": [ [ 61, 71 ] ], "normalized": [] }, { "id": "3803", "type": "Intervention_Pharmacological", "text": [ "lamivudine" ], "offsets": [ ...
[]
[]
[]
3811
10870534
[ { "id": "3812", "type": "document", "text": [ "Clinical pathway for fractured neck of femur : a prospective , controlled study . OBJECTIVE To assess outcomes of using a clinical pathway for managing patients with fractured neck of femur . DESIGN Prospective , pseudorandomised , controlled trial . ...
[ { "id": "3813", "type": "Intervention_Other", "text": [ "Management guided by a clinical pathway ( 55 patients ) or established standard of care" ], "offsets": [ [ 577, 664 ] ], "normalized": [] }, { "id": "3814", "type": "Outcome_Other", ...
[]
[]
[]
3822
10871578
[ { "id": "3823", "type": "document", "text": [ "Plasma antioxidant status after high-dose chemotherapy : a randomized trial of parenteral nutrition in bone marrow transplantation patients . BACKGROUND Chemotherapy and radiation therapy result in increased free radical formation and depletion of tis...
[ { "id": "3824", "type": "Intervention_Pharmacological", "text": [ "high-dose chemotherapy" ], "offsets": [ [ 32, 54 ] ], "normalized": [] }, { "id": "3825", "type": "Intervention_Pharmacological", "text": [ "Chemotherapy and radiati...
[]
[]
[]
3856
10889149
[ { "id": "3857", "type": "document", "text": [ "Atrophy and intestinal metaplasia one year after cure of H. pylori infection : a prospective , randomized study . BACKGROUND & AIMS Helicobacter pylori-infected gastric mucosa evolves through stages of chronic gastritis , intestinal metaplasia ( IM ) ...
[ { "id": "3858", "type": "Intervention_Physical", "text": [ "upper endoscopy with biopsy" ], "offsets": [ [ 494, 521 ] ], "normalized": [] }, { "id": "3859", "type": "Intervention_Pharmacological", "text": [ "1-week course of omepraz...
[]
[]
[]
3877
10889804
[ { "id": "3878", "type": "document", "text": [ "The Finnish Diabetes Prevention Study . The aim of the Finnish Diabetes Prevention Study is to assess the efficacy of an intensive diet-exercise programme in preventing or delaying type 2 diabetes in individuals with impaired glucose tolerance ( IGT )...
[ { "id": "3879", "type": "Intervention_Pharmacological", "text": [ "intensive diet-exercise programme" ], "offsets": [ [ 121, 154 ] ], "normalized": [] }, { "id": "3880", "type": "Intervention_Pharmacological", "text": [ "individual ...
[]
[]
[]
3901
10901647
[ { "id": "3902", "type": "document", "text": [ "Transesophageal echocardiography in quantification of emboli during femoral nailing : reamed versus unreamed techniques . We quantified the embolic load to the lungs created with two different techniques of femoral nailing . Eleven patients with 12 tr...
[ { "id": "3903", "type": "Intervention_Physical", "text": [ "Transesophageal echocardiography" ], "offsets": [ [ 0, 32 ] ], "normalized": [] }, { "id": "3904", "type": "Intervention_Surgical", "text": [ "reamed" ], "offsets":...
[]
[]
[]
3916
10902449
[ { "id": "3917", "type": "document", "text": [ "[ Comparative study between 5 % prilocaine and 2 % mepivacaine by the subarachnoid route in transurethral resections ] . OBJECTIVE To compare the duration of spinal block with 5 % prilocaine and 2 % mepivacaine in short procedures for transurethral re...
[ { "id": "3918", "type": "Intervention_Pharmacological", "text": [ "5 % prilocaine" ], "offsets": [ [ 28, 42 ] ], "normalized": [] }, { "id": "3919", "type": "Intervention_Pharmacological", "text": [ "2 % mepivacaine" ], "off...
[]
[]
[]
3944
10926339
[ { "id": "3945", "type": "document", "text": [ "Comparison of high and low dose of the inhaled steroid , budesonide , as an initial treatment in newly detected asthma . The importance of early initiation of inhaled steroids even in mild asthma has been documented in several studies . It is not , ho...
[ { "id": "3946", "type": "Intervention_Pharmacological", "text": [ "inhaled steroid , budesonide" ], "offsets": [ [ 39, 67 ] ], "normalized": [] }, { "id": "3947", "type": "Intervention_Pharmacological", "text": [ "inhaled steroids" ...
[]
[]
[]
3971
10928228
[ { "id": "3972", "type": "document", "text": [ "Is a calculated total hip BMD of clinical use ? The diagnosis of osteoporosis is based on bone mass measurement . To avoid the errors associated with the measurement of spinal bone density the total hip has been accepted as the standard measurement si...
[ { "id": "3973", "type": "Outcome_Physical", "text": [ "total hip BMD" ], "offsets": [ [ 16, 29 ] ], "normalized": [] }, { "id": "3974", "type": "Outcome_Physical", "text": [ "Total hip BMD" ], "offsets": [ [ 69...
[]
[]
[]
3988
10934908
[ { "id": "3989", "type": "document", "text": [ "On the search for the neurophysiological manifestation of recollective experience . M.E . Smith ( 1993 ) obtained event-related brain potentials ( ERPs ) from subjects performing a recognition memory task using \" remember \" ( R ) and \" know \" ( K ...
[ { "id": "3990", "type": "Intervention_Psychological", "text": [ "recognition memory task" ], "offsets": [ [ 181, 204 ] ], "normalized": [] }, { "id": "3991", "type": "Outcome_Physical", "text": [ "P300 latency jitter" ], "of...
[]
[]
[]
3996
10939601
[ { "id": "3997", "type": "document", "text": [ "5-fluorouracil plus folinic acid with or without ifosfamide in advanced colorectal cancer : a phase II randomized trial . AIM This phase II trial evaluated the biomodulation of 5-fluorouracil ( 5-FU ) plus folinic acid ( FA ) with or without ifosfamid...
[ { "id": "3998", "type": "Intervention_Pharmacological", "text": [ "5-fluorouracil" ], "offsets": [ [ 0, 14 ] ], "normalized": [] }, { "id": "3999", "type": "Intervention_Pharmacological", "text": [ "folinic acid" ], "offsets...
[]
[]
[]
4025
10945514
[ { "id": "4026", "type": "document", "text": [ "Combination hydrocodone and ibuprofen versus combination codeine and acetaminophen for the treatment of chronic pain . OBJECTIVE The objective of this study was to compare the effectiveness of combination hydrocodone 7.5 mg and ibuprofen 200 mg with t...
[ { "id": "4027", "type": "Intervention_Pharmacological", "text": [ "hydrocodone and ibuprofen" ], "offsets": [ [ 12, 37 ] ], "normalized": [] }, { "id": "4028", "type": "Intervention_Pharmacological", "text": [ "codeine and acetamino...
[]
[]
[]
4075
10947757
[ { "id": "4076", "type": "document", "text": [ "The effect of halothane and isoflurane on plasma cytokine levels . The aim of this study was to investigate the effect of halothane vs. isoflurane on cytokine production during minor elective surgery . Forty adult patients , ASA I-II were randomly all...
[ { "id": "4077", "type": "Intervention_Pharmacological", "text": [ "halothane" ], "offsets": [ [ 14, 23 ] ], "normalized": [] }, { "id": "4078", "type": "Intervention_Pharmacological", "text": [ "isoflurane" ], "offsets": [ ...
[]
[]
[]
4098
10957888
[ { "id": "4099", "type": "document", "text": [ "A comparative efficacy and safety study of clarithromycin , roxithromycin and erythromycin stearate in mild pneumonia . The efficacy and safety of clarithromycin , roxithromycin and erythromycin stearate in mild pneumonia were compared in an open rand...
[ { "id": "4100", "type": "Intervention_Pharmacological", "text": [ "clarithromycin" ], "offsets": [ [ 43, 57 ] ], "normalized": [] }, { "id": "4101", "type": "Intervention_Pharmacological", "text": [ "roxithromycin" ], "offse...
[]
[]
[]
4135
10960380
[ { "id": "4136", "type": "document", "text": [ "The anesthetic and recovery profile of two doses ( 60 and 80 mg ) of plain mepivacaine for ambulatory spinal anesthesia . UNLABELLED Reports of transient neurological symptoms with the use of subarachnoid lidocaine has generated interest in alternate ...
[ { "id": "4137", "type": "Intervention_Pharmacological", "text": [ "plain mepivacaine" ], "offsets": [ [ 69, 86 ] ], "normalized": [] }, { "id": "4138", "type": "Intervention_Pharmacological", "text": [ "subarachnoid lidocaine" ]...
[]
[]
[]
4162
10963640
[ { "id": "4163", "type": "document", "text": [ "Epirubicin-based chemotherapy in metastatic breast cancer patients : role of dose-intensity and duration of treatment . PURPOSE To determine whether the duration and the dose of epirubicin modify the long-term outcome of patients with metastatic breas...
[ { "id": "4164", "type": "Intervention_Pharmacological", "text": [ "Epirubicin-based chemotherapy" ], "offsets": [ [ 0, 29 ] ], "normalized": [] }, { "id": "4165", "type": "Intervention_Pharmacological", "text": [ "epirubicin" ],...
[]
[]
[]
4194
10968308
[ { "id": "4195", "type": "document", "text": [ "The effect of case management on the costs of health care for enrollees in Medicare Plus Choice plans : a randomized trial . OBJECTIVE To measure the effects of case management on an older population 's costs of health care . DESIGN A 1-year randomize...
[ { "id": "4196", "type": "Intervention_Educational", "text": [ "case management" ], "offsets": [ [ 14, 29 ] ], "normalized": [] }, { "id": "4197", "type": "Intervention_Other", "text": [ "Screening for high risk and provision of" ...
[]
[]
[]
4209
10969304
[ { "id": "4210", "type": "document", "text": [ "Physostigmine reverses propofol-induced unconsciousness and attenuation of the auditory steady state response and bispectral index in human volunteers . BACKGROUND It is postulated that alteration of central cholinergic transmission plays an important...
[ { "id": "4211", "type": "Intervention_Pharmacological", "text": [ "Physostigmine" ], "offsets": [ [ 0, 13 ] ], "normalized": [] }, { "id": "4212", "type": "Intervention_Pharmacological", "text": [ "physostigmine" ], "offsets...
[]
[]
[]
4234
10971307
[ { "id": "4235", "type": "document", "text": [ "Influence of asimadoline , a new kappa-opioid receptor agonist , on tubular water absorption and vasopressin secretion in man . AIMS The purpose of the study was to investigate the effects of asimadoline , a new kappa-opioid agonist , on renal functio...
[ { "id": "4236", "type": "Intervention_Pharmacological", "text": [ "asimadoline" ], "offsets": [ [ 13, 24 ] ], "normalized": [] }, { "id": "4237", "type": "Intervention_Pharmacological", "text": [ "asimadoline" ], "offsets": ...
[]
[]
[]
4259
10971538
[ { "id": "4260", "type": "document", "text": [ "Uvulopalatopharyngoplasty versus laser assisted uvulopalatoplasty for the treatment of snoring : an objective randomised clinical trial . This study was designed to evaluate objectively the clinical effectiveness of surgery for snoring and to compare ...
[ { "id": "4261", "type": "Intervention_Surgical", "text": [ "Uvulopalatopharyngoplasty" ], "offsets": [ [ 0, 25 ] ], "normalized": [] }, { "id": "4262", "type": "Intervention_Physical", "text": [ "laser assisted uvulopalatoplasty" ...
[]
[]
[]
4276
10973645
[ { "id": "4277", "type": "document", "text": [ "Randomized trial of a \" stage-of-change \" oriented smoking cessation intervention in infertile and pregnant women . OBJECTIVE To assess a \" stage-of-change \" oriented smoking cessation intervention for infertile and pregnant women , compared with ...
[ { "id": "4278", "type": "Intervention_Educational", "text": [ "\" stage-of-change \" oriented smoking cessation intervention" ], "offsets": [ [ 22, 81 ] ], "normalized": [] }, { "id": "4279", "type": "Intervention_Educational", "text": [ ...
[]
[]
[]
4293
10986219
[ { "id": "4294", "type": "document", "text": [ "Effect of L-ornithine-L-aspartate on patients with and without TIPS undergoing glutamine challenge : a double blind , placebo controlled trial . BACKGROUND AND AIM An oral glutamine load in cirrhotic patients awaiting liver transplantation was shown t...
[ { "id": "4295", "type": "Intervention_Pharmacological", "text": [ "L-ornithine-L-aspartate" ], "offsets": [ [ 10, 33 ] ], "normalized": [] }, { "id": "4296", "type": "Intervention_Pharmacological", "text": [ "L-Ornithine-L-aspartate...
[]
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4317
10986363
[ { "id": "4318", "type": "document", "text": [ "Superior modulation of activation levels of stimulus representations does not underlie superior discrimination in autism . The performance of children with and without autism was compared in object-based positive and negative priming tasks within a vi...
[ { "id": "4319", "type": "Intervention_Educational", "text": [ "object-based positive and negative priming tasks" ], "offsets": [ [ 191, 239 ] ], "normalized": [] }, { "id": "4320", "type": "Intervention_Educational", "text": [ "visu...
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4329
10992833
[ { "id": "4330", "type": "document", "text": [ "Onset/offset characteristics and intubating conditions of rapacuronium : a comparison with rocuronium . We compared onset and offset of action and tracheal intubating conditions after rapacuronium and rocuronium in 60 patients in a randomized , assess...
[ { "id": "4331", "type": "Intervention_Pharmacological", "text": [ "rapacuronium" ], "offsets": [ [ 58, 70 ] ], "normalized": [] }, { "id": "4332", "type": "Intervention_Pharmacological", "text": [ "rocuronium" ], "offsets": ...
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4355
10992834
[ { "id": "4356", "type": "document", "text": [ "Comparison of succinylcholine with two doses of rocuronium using a new method of monitoring neuromuscular block at the laryngeal muscles by surface laryngeal electromyography . We compared the onset of neuromuscular block with succinylcholine ( 1 mg k...
[ { "id": "4357", "type": "Intervention_Pharmacological", "text": [ "succinylcholine" ], "offsets": [ [ 14, 29 ] ], "normalized": [] }, { "id": "4358", "type": "Intervention_Pharmacological", "text": [ "rocuronium" ], "offsets...
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4378
10993031
[ { "id": "4379", "type": "document", "text": [ "Sublingual administration of micronized estradiol and progesterone , with and without micronized testosterone : effect on biochemical markers of bone metabolism and bone mineral density . OBJECTIVES The purpose of this investigation was to evaluate th...
[ { "id": "4380", "type": "Intervention_Pharmacological", "text": [ "micronized estradiol" ], "offsets": [ [ 29, 49 ] ], "normalized": [] }, { "id": "4381", "type": "Intervention_Pharmacological", "text": [ "progesterone" ], "...
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4426
10997806
[ { "id": "4427", "type": "document", "text": [ "Paclitaxel ( 175 mg/m2 ) plus carboplatin ( 6 AUC ) versus paclitaxel ( 225 mg/m2 ) plus carboplatin ( 6 AUC ) in advanced non-small-cell lung cancer ( NSCLC ) : a multicenter randomized trial . Hellenic Cooperative Oncology Group ( HeCOG ) . PURPOSE ...
[ { "id": "4428", "type": "Intervention_Pharmacological", "text": [ "Paclitaxel" ], "offsets": [ [ 0, 10 ] ], "normalized": [] }, { "id": "4429", "type": "Intervention_Pharmacological", "text": [ "carboplatin" ], "offsets": [ ...
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4454
1100179
[ { "id": "4455", "type": "document", "text": [ "Analysis of treatment in childhood leukaemia . I. Predisposition to methotrexate-induced neutropenia after craniospinal irradiation . Report to the Medical Research Council of the Working Party on Leukaemia in Childhood . The degree of drug-induced ne...
[ { "id": "4456", "type": "Intervention_Pharmacological", "text": [ "methotrexate" ], "offsets": [ [ 68, 80 ] ], "normalized": [] }, { "id": "4457", "type": "Outcome_Other", "text": [ "Analysis of treatment" ], "offsets": [ ...
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