Toward Reliable Biomedical Hypothesis Generation: Evaluating Truthfulness and Hallucination in Large Language Models
Paper • 2505.14599 • Published • 2
Type stringclasses 4
values | ConceptID stringlengths 1 31 | mention_counts stringlengths 7 7.84M | mention stringlengths 1 99 ⌀ |
|---|---|---|---|
Disease | MESH:C000597569 | {'teratoid rhabdoid tumors': 134, 'ATRTs': 115, 'atypical teratoid/rhabdoid tumors': 310, 'teratoid/rhabdoid tumor': 355, 'atypical teratoid rhabdoid tumor': 281, 'Atypical teratoid rhabdoid tumor': 104, 'teratoid rhabdoid tumor': 236, 'Atypical rhabdoid/teratoid tumor': 4, 'atypical rhabdoid/teratoid tumor': 15, 'Atyp... | ATRT |
Disease | MESH:C000598644 | {'LCC': 50, 'Leukoencephalopathy with cerebral calcifications and cysts': 6, 'Labrune syndrome': 45, 'Leukoencephalopathy with brain calcifications and cysts': 6, 'renal cyst with calcification': 1, 'leukoencephalopathy with calcifications and cysts': 21, 'Leukoencephalopathy with Calcifications and Cysts': 8, 'Leukoen... | LCC |
Disease | MESH:C000598645 | {'Spheroid': 902, 'spheroid': 321, 'hCS': 8, 'hCSs': 6, 'Spheroid-Xenograft': 1, 'PDSX': 3, 'PDSXs': 1, 'spheroids': 249, 'spheroid reduction': 1, 'spheroid body myopathy': 28, 'Spheroids': 43, 'spheroidal degeneration': 38, 'MCS': 55, 'NM-spheroids': 1, 'Spheroidal degeneration': 13, 'ES': 1, 'endometriotic spheroids'... | Spheroid |
Disease | MESH:C000598744 | {'idiopathic myopathies': 26, 'autoimmune idiopathic myopathy': 1, 'congenital and idiopathic myopathies': 1, 'rheumatic or idiopathic myopathies': 1, 'idiopathic necrotizing myopathies': 4, 'Chronic idiopathic myopathies': 1, 'idiopathic interstitial myopathy': 2, 'familial inflammatory syndrome': 8, 'idiopathic myopa... | idiopathic myopathies |
Disease | MESH:C000598941 | {'keratoactinomycosis': 1} | keratoactinomycosis |
Disease | MESH:C000600608 | {'mcEDS-CHST14': 15, 'mcEDS': 27, 'Musculocontractural Ehlers-Danlos Syndrome': 14, 'musculocontractural EDS': 19, 'Musculocontractural EDS': 15, 'Musculocontractural Ehlers-Danlos syndrome': 24, 'mcEDS-': 9, 'Adducted thumb-clubfoot syndrome': 5, 'musculocontractural type 1': 5, 'Dundar syndrome': 2, 'Dundar Syndrome'... | mcEDS |
Disease | MESH:C000601856 | {'non-ketotic syndrome': 4, 'Hyperosmolar non-ketotic syndrome': 1, 'non-ketotic hyperosmolar syndrome': 6, 'hyperglycemic non-ketotic syndrome': 7, 'hyperosmolar non-ketotic syndrome': 5, 'Hyperosmolar non-ketotic diabetic syndrome': 3, 'HHNS': 2, 'Hyperglycaemic hyperosmolar non-ketotic syndrome': 2, 'hyperglycaemic ... | hyperglycemic non-ketotic syndrome |
Disease | MESH:C000603735 | {', nongoitrous': 1, 'nongoitrous euthyroid hyperthyrotropinemia': 1, 'Nongoitrous': 1, 'nongoitrous dyshormonogenetic hypothyroidism': 1, 'congenital nongoitrous hypothyroidism': 6, 'Congenital nongoitrous hypothyroidism': 3, 'nongoitrous': 4, 'primary nongoitrous hypothyroidism': 2, 'nongoitrous hypothyroidism': 3, '... | congenital nongoitrous hypothyroidism |
Disease | MESH:C000604661 | {'sinus tarsi': 179, 'sinus tarsi syndrome': 125, 'Sinus Tarsi Syndrome': 9, 'Tarsi stout': 1, 'sinus tarsi pain': 35, 'Sinus tarsi syndrome': 46, 'Tarsi': 8, 'Dorsal tarsi': 1, 'Prothoracic tarsi': 1, 'tarsi': 85, 'tarsus/tarsi 1': 1, 'tarsus/tarsi 2': 1, 'cunaxid peg organ on tarsi': 1, 'sinus tarsi and tendon abnorm... | sinus tarsi |
Disease | MESH:C000608854 | {'Optic meningioma': 3, 'Meningiomas of the optic nerve': 3, 'meningiomas of the optic nerve': 4, 'secondary meningioma of the optic nerve': 1, 'optic nerve meningioma': 96, 'Optic nerve meningioma': 13, 'ONM': 2, 'optic nerve meningiomas': 42, 'meningioma of the optic nerve': 15, 'optic nerve meningothelial meningioma... | optic nerve meningioma |
Disease | MESH:C000610012 | {'congenital isolated thyrotropin deficiency': 2, 'TSH deficiency': 1, 'ITD': 1} | congenital isolated thyrotropin deficiency |
Disease | MESH:C000613206 | {'Poroid Hidradenocarcinoma of the Ankle': 1, 'poroid neoplasm': 18, 'poroid neoplasms': 28, 'Poroid hidradenoma': 26, 'Poroid neoplasm': 2, 'poroid hidradenoma': 51, 'PH': 13, 'POROID CELL': 1, 'poroid': 2, 'poroid tumors': 12, 'Poroid Hidradenoma': 9, 'Papillary poroid hidradenoma': 3, 'poroid carcinoma': 1, 'poroid ... | poroid hidradenoma |
Disease | MESH:C000623088 | {'1I-1L': 19, '1I-T': 4, 'CMCC(F)T 1i': 1, '1I-1N': 3, 'type 1I diabetics': 1, '1I': 4, 'FIGURE 7-1I': 1, '1I-1P': 2, 'factor V/1I deficiency': 1, 'lupus 1i': 1, 'EVAL-1I': 1, '1I-L': 1, 'MPS 1is': 1, 'Charcot-Marie-Tooth syndrome type 1I': 1, 'CMT1I': 1, 'Maxilla Bone Type 1I, II, III, IV': 1, 'Gartland type 1I hum... | 1I-1L |
Disease | MESH:C000625499 | {'aponeurotic': 36, 'calcifying aponeurotic fibroma': 87, 'Calcifying aponeurotic fibroma': 52, 'aponeurotic ptosis': 113, 'aponeurotic fibroma': 31, 'CAF': 23, 'juvenile aponeurotic fibroma': 37, 'calcifying fibroma lipoma': 1, 'Calcifying Aponeurotic Fibroma': 3, 'Calcifying aponeurotic fibroma of the thigh': 1, 'apo... | aponeurotic ptosis |
Disease | MESH:C000626124 | {'NGLY1 deficiency': 62, 'NGly1 disease': 1, 'NGly1 deficiency': 1, 'NGLY1 deficient': 2, 'Ngly1 deficiency': 4, 'NGLY1-deficiency': 10, 'NGLY1-': 3, 'NGLY1-deficient': 2, 'dsm-iv-disorders': 1, 'NGLY1 deficiency disease': 1, 'NGLY1-deficiency disease': 1, 'NGLY1 deficiency autosomal recessive disorder': 1, 'NGLY1 Defi... | NGLY1 deficiency |
Here is the processed node data from PubTator used for knowledge-enhanced hypothesis generation in the TruthHypo benchmark (IJCAI 25), which is designed to evaluate the capabilities of LLMs in generating truthful scientific hypothesis. The paper is available at https://arxiv.org/abs/2505.14599.