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MED-10 | Statin Use and Breast Cancer Survival: A Nationwide Cohort Study from Finland | Recent studies have suggested that statins, an established drug group in the prevention of cardiovascular mortality, could delay or prevent breast cancer recurrence but the effect on disease-specific mortality remains unclear. We evaluated risk of breast cancer death among statin users in a population-based cohort of b... | http://www.ncbi.nlm.nih.gov/pubmed/25329299 | Statin Use and Breast Cancer Survival: A Nationwide Cohort Study from Finland Recent studies have suggested that statins, an established drug group in the prevention of cardiovascular mortality, could delay or prevent breast cancer recurrence but the effect on disease-specific mortality remains unclear. We evaluated ri... |
MED-14 | Statin use after diagnosis of breast cancer and survival: a population-based cohort study. | BACKGROUND: Preclinical studies have shown that statins, particularly simvastatin, can prevent growth in breast cancer cell lines and animal models. We investigated whether statins used after breast cancer diagnosis reduced the risk of breast cancer-specific, or all-cause, mortality in a large cohort of breast cancer p... | http://www.ncbi.nlm.nih.gov/pubmed/25304447 | Statin use after diagnosis of breast cancer and survival: a population-based cohort study. BACKGROUND: Preclinical studies have shown that statins, particularly simvastatin, can prevent growth in breast cancer cell lines and animal models. We investigated whether statins used after breast cancer diagnosis reduced the r... |
MED-118 | Alkylphenols in human milk and their relations to dietary habits in central Taiwan. | The aims of this study were to determine the concentrations of 4-nonylphenol (NP) and 4-octylphenol (OP) in 59 human milk samples and to examine related factors including mothers' demographics and dietary habits. Women who consumed over the median amount of cooking oil had significantly higher OP concentrations (0.98 n... | http://www.ncbi.nlm.nih.gov/pubmed/20435081%20 | Alkylphenols in human milk and their relations to dietary habits in central Taiwan. The aims of this study were to determine the concentrations of 4-nonylphenol (NP) and 4-octylphenol (OP) in 59 human milk samples and to examine related factors including mothers' demographics and dietary habits. Women who consumed over... |
MED-301 | Methylmercury: A Potential Environmental Risk Factor Contributing to Epileptogenesis | Epilepsy or seizure disorder is one of the most common neurological diseases in humans. Although genetic mutations in ion channels and receptors and some other risk factors such as brain injury are linked to epileptogenesis, the underlying cause for the majority of epilepsy cases remains unknown. Gene-environment inter... | http://www.ncbi.nlm.nih.gov/pubmed/22206970 | Methylmercury: A Potential Environmental Risk Factor Contributing to Epileptogenesis Epilepsy or seizure disorder is one of the most common neurological diseases in humans. Although genetic mutations in ion channels and receptors and some other risk factors such as brain injury are linked to epileptogenesis, the underl... |
MED-306 | Sensitivity of Continuous Performance Test (CPT) at Age 14 Years to Developmental Methylmercury Exposure | Hit Reaction Time latencies (HRT) in the Continuous Performance Test (CPT) measure the speed of visual information processing. The latencies may involve different neuropsychological functions depending on the time from test initiation, i.e., first orientation, learning and habituation, then cognitive processing and foc... | http://www.ncbi.nlm.nih.gov/pubmed/20699117 | Sensitivity of Continuous Performance Test (CPT) at Age 14 Years to Developmental Methylmercury Exposure Hit Reaction Time latencies (HRT) in the Continuous Performance Test (CPT) measure the speed of visual information processing. The latencies may involve different neuropsychological functions depending on the time f... |
MED-329 | Phosphate is a vascular toxin. | Elevated phosphate (P) levels are seen in advanced renal failure and, together with dysregulated calcium, parathyroid hormone and vitamin D levels, contribute to the complex of chronic kidney disease-mineral and bone disease (CKD-MBD). Converging evidence from in vitro, clinical and epidemiological studies suggest that... | http://www.ncbi.nlm.nih.gov/pubmed/23161206 | Phosphate is a vascular toxin. Elevated phosphate (P) levels are seen in advanced renal failure and, together with dysregulated calcium, parathyroid hormone and vitamin D levels, contribute to the complex of chronic kidney disease-mineral and bone disease (CKD-MBD). Converging evidence from in vitro, clinical and epide... |
MED-330 | Dietary Phosphorus Acutely Impairs Endothelial Function | Excessive dietary phosphorus may increase cardiovascular risk in healthy individuals as well as in patients with chronic kidney disease, but the mechanisms underlying this risk are not completely understood. To determine whether postprandial hyperphosphatemia may promote endothelial dysfunction, we investigated the acu... | http://www.ncbi.nlm.nih.gov/pubmed/19406976 | Dietary Phosphorus Acutely Impairs Endothelial Function Excessive dietary phosphorus may increase cardiovascular risk in healthy individuals as well as in patients with chronic kidney disease, but the mechanisms underlying this risk are not completely understood. To determine whether postprandial hyperphosphatemia may ... |
MED-332 | Public health impact of dietary phosphorus excess on bone and cardiovascular health in the general population. | This review explores the potential adverse impact of the increasing phosphorus content in the American diet on renal, cardiovascular, and bone health of the general population. Increasingly, studies show that phosphorus intakes in excess of the nutrient needs of a healthy population may significantly disrupt the hormon... | http://www.ncbi.nlm.nih.gov/pubmed/23719553 | Public health impact of dietary phosphorus excess on bone and cardiovascular health in the general population. This review explores the potential adverse impact of the increasing phosphorus content in the American diet on renal, cardiovascular, and bone health of the general population. Increasingly, studies show that ... |
MED-334 | Differences among total and in vitro digestible phosphorus content of plant foods and beverages. | OBJECTIVE: Among plant foods, grain products, legumes, and seeds are important sources of phosphorus (P). Current data on P content and absorbability of P from these foods are lacking. Measurement of in vitro digestible P (DP) content of foods may reflect absorbability of P. The objective of this study was to measure b... | http://www.ncbi.nlm.nih.gov/pubmed/21741857 | Differences among total and in vitro digestible phosphorus content of plant foods and beverages. OBJECTIVE: Among plant foods, grain products, legumes, and seeds are important sources of phosphorus (P). Current data on P content and absorbability of P from these foods are lacking. Measurement of in vitro digestible P (... |
MED-335 | Differences among total and in vitro digestible phosphorus content of meat and milk products. | OBJECTIVE: Meat and milk products are important sources of dietary phosphorus (P) and protein. The use of P additives is common both in processed cheese and meat products. Measurement of in vitro digestible phosphorus (DP) content of foods may reflect absorbability of P. The objective of this study was to measure both ... | http://www.ncbi.nlm.nih.gov/pubmed/21978846 | Differences among total and in vitro digestible phosphorus content of meat and milk products. OBJECTIVE: Meat and milk products are important sources of dietary phosphorus (P) and protein. The use of P additives is common both in processed cheese and meat products. Measurement of in vitro digestible phosphorus (DP) con... |
MED-398 | The grapefruit: an old wine in a new glass? Metabolic and cardiovascular perspectives | Summary Grapefruit is a popular, tasty and nutritive fruit enjoyed globally. Biomedical evidence in the last 10 years has, however, shown that consumption of grapefruit or its juice is associated with drug interactions, which, in some cases, have been fatal. Grapefruit-induced drug interactions are unique in that the c... | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3721883/ | The grapefruit: an old wine in a new glass? Metabolic and cardiovascular perspectives Summary Grapefruit is a popular, tasty and nutritive fruit enjoyed globally. Biomedical evidence in the last 10 years has, however, shown that consumption of grapefruit or its juice is associated with drug interactions, which, in some... |
MED-557 | Dysmenorrhea. | Dysmenorrhea is the leading cause of recurrent short-term school absence in adolescent girls and a common problem in women of reproductive age. Risk factors for dysmenorrhea include nulliparity, heavy menstrual flow, smoking, and depression. Empiric therapy can be initiated based on a typical history of painful menses ... | http://www.ncbi.nlm.nih.gov/pubmed/15686299 | Dysmenorrhea. Dysmenorrhea is the leading cause of recurrent short-term school absence in adolescent girls and a common problem in women of reproductive age. Risk factors for dysmenorrhea include nulliparity, heavy menstrual flow, smoking, and depression. Empiric therapy can be initiated based on a typical history of p... |
MED-666 | Is there a role for surgery in the treatment of mastalgia? | Breast pain is a common condition affecting most women at some stage in their reproductive life. Mastalgia is resistant to treatment in 6% of cyclical and 26% non-cyclical patients. Surgery is not widely used to treat this condition and only considered in patients with severe mastalgia resistant to medication. The aims... | http://www.ncbi.nlm.nih.gov/pubmed/14965747 | Is there a role for surgery in the treatment of mastalgia? Breast pain is a common condition affecting most women at some stage in their reproductive life. Mastalgia is resistant to treatment in 6% of cyclical and 26% non-cyclical patients. Surgery is not widely used to treat this condition and only considered in patie... |
MED-691 | Ginger in the prevention of nausea and vomiting: a review. | Nausea and vomiting are physiological processes experienced by every human being at some stage of their life. They are complex protective mechanisms and the symptoms are influenced by the emetogenic response and stimuli. However, when these symptoms recur frequently, they can significantly reduce the quality of life an... | http://www.ncbi.nlm.nih.gov/pubmed/23638927 | Ginger in the prevention of nausea and vomiting: a review. Nausea and vomiting are physiological processes experienced by every human being at some stage of their life. They are complex protective mechanisms and the symptoms are influenced by the emetogenic response and stimuli. However, when these symptoms recur frequ... |
MED-692 | The effectiveness and safety of ginger for pregnancy-induced nausea and vomiting: a systematic review. | BACKGROUND: Ginger has been used throughout the world as a therapeutic agent for centuries. The herb is increasingly used in Western society also, with one of the most common indications being pregnancy-induced nausea and vomiting (PNV). OBJECTIVES: To examine the evidence for the safety and effectiveness of ginger for... | http://www.ncbi.nlm.nih.gov/pubmed/22951628 | The effectiveness and safety of ginger for pregnancy-induced nausea and vomiting: a systematic review. BACKGROUND: Ginger has been used throughout the world as a therapeutic agent for centuries. The herb is increasingly used in Western society also, with one of the most common indications being pregnancy-induced nausea... |
MED-702 | The efficacy and safety of liraglutide. | AIM OF THE REVIEW: To systematically analyze the efficacy and safety of liraglutide for the treatment of diabetes mellitus in comparison to other mono- and combination therapies. METHOD: PubMed (any date) and EMBASE (all years) search was conducted with liraglutide as a search term. Phase III clinical trials retrieved ... | http://www.ncbi.nlm.nih.gov/pubmed/21952951 | The efficacy and safety of liraglutide. AIM OF THE REVIEW: To systematically analyze the efficacy and safety of liraglutide for the treatment of diabetes mellitus in comparison to other mono- and combination therapies. METHOD: PubMed (any date) and EMBASE (all years) search was conducted with liraglutide as a search te... |
MED-706 | The aqueous extract of Hibiscus sabdariffa calices modulates the production of monocyte chemoattractant protein-1 in humans. | Diet supplementation and/or modulation is an important strategy to significantly improve human health. The search of plants as additional sources of bioactive phenolic compounds is relevant in this context. The aqueous extract of Hibiscus sabdariffa is rich in anthocyanins and other phenolic compounds including hydroxy... | http://www.ncbi.nlm.nih.gov/pubmed/19765963 | The aqueous extract of Hibiscus sabdariffa calices modulates the production of monocyte chemoattractant protein-1 in humans. Diet supplementation and/or modulation is an important strategy to significantly improve human health. The search of plants as additional sources of bioactive phenolic compounds is relevant in th... |
MED-707 | Uricosuric effect of Roselle (Hibiscus sabdariffa) in normal and renal-stone former subjects. | AIM OF THE STUDY: The Roselle (Hibiscus sabdariffa) was investigated for its uricosuric effect. MATERIALS AND METHODS: A human model with nine subjects with no history of renal stones (non-renal stone, NS) and nine with a history of renal stones (RS) was used in this study. A cup of tea made from 1.5 g of dry Roselle c... | http://www.ncbi.nlm.nih.gov/pubmed/18423919 | Uricosuric effect of Roselle (Hibiscus sabdariffa) in normal and renal-stone former subjects. AIM OF THE STUDY: The Roselle (Hibiscus sabdariffa) was investigated for its uricosuric effect. MATERIALS AND METHODS: A human model with nine subjects with no history of renal stones (non-renal stone, NS) and nine with a hist... |
MED-708 | Inhibitory effect of marinades with hibiscus extract on formation of heterocyclic aromatic amines and sensory quality of fried beef patties. | Heterocyclic aromatic amines (HAA) are carcinogenic compounds found in the crust of fried meat. The objective was to examine the possibility of inhibiting HAA formation in fried beef patties by using marinades with different concentrations of hibiscus extract (Hibiscus sabdariffa) (0.2, 0.4, 0.6, 0.8 g/100g). After fry... | http://www.ncbi.nlm.nih.gov/pubmed/20418021 | Inhibitory effect of marinades with hibiscus extract on formation of heterocyclic aromatic amines and sensory quality of fried beef patties. Heterocyclic aromatic amines (HAA) are carcinogenic compounds found in the crust of fried meat. The objective was to examine the possibility of inhibiting HAA formation in fried b... |
MED-709 | Testicular effects of sub-chronic administration of Hibiscus sabdariffa calyx aqueous extract in rats. | The sub-chronic effect of Hibiscus sabdariffa (HS) calyx aqueous extract on the rat testes was investigated with a view to evaluate the pharmacological basis for the use of HS calyx extract as an aphrodisiac. Three test groups received different doses of 1.15, 2.30, and 4.60 g/kg based on the LD(50). The extracts were ... | http://www.ncbi.nlm.nih.gov/pubmed/15019726 | Testicular effects of sub-chronic administration of Hibiscus sabdariffa calyx aqueous extract in rats. The sub-chronic effect of Hibiscus sabdariffa (HS) calyx aqueous extract on the rat testes was investigated with a view to evaluate the pharmacological basis for the use of HS calyx extract as an aphrodisiac. Three te... |
MED-711 | Effects of Hibiscus sabdariffa extract powder and preventive treatment (diet) on the lipid profiles of patients with metabolic syndrome (MeSy). | Insulin resistance, obesity, hypertension, and dyslipidemia are strongly associated with metabolic syndrome (MeSy), which is considered to be a reversible clinical stage before its evolution to coronary heart disease and diabetes. Currently, the antihypertensive and hypolipidemic properties of aqueous Hibiscus sabdarif... | http://www.ncbi.nlm.nih.gov/pubmed/19962289 | Effects of Hibiscus sabdariffa extract powder and preventive treatment (diet) on the lipid profiles of patients with metabolic syndrome (MeSy). Insulin resistance, obesity, hypertension, and dyslipidemia are strongly associated with metabolic syndrome (MeSy), which is considered to be a reversible clinical stage before... |
MED-712 | Chemopreventive properties and molecular mechanisms of the bioactive compounds in Hibiscus sabdariffa Linne. | Hibiscus sabdariffa Linne is a traditional Chinese rose tea and has been effectively used in folk medicines for treatment of hypertension, inflammatory conditions. H. sabdariffa aqueous extracts (HSE) were prepared from the dried flowers of H. sabdariffa L., which are rich in phenolic acids, flavonoids and anthocyanins... | http://www.ncbi.nlm.nih.gov/pubmed/21291361 | Chemopreventive properties and molecular mechanisms of the bioactive compounds in Hibiscus sabdariffa Linne. Hibiscus sabdariffa Linne is a traditional Chinese rose tea and has been effectively used in folk medicines for treatment of hypertension, inflammatory conditions. H. sabdariffa aqueous extracts (HSE) were prepa... |
MED-713 | Effects of water extract of Hibiscus sabdariffa, Linn (Malvaceae) 'Roselle' on excretion of a diclofenac formulation. | The effect of beverages prepared from the dried calyx of the flowers of Hibiscus sabdariffa on the excretion of diclofenac was investigated using a controlled study in healthy human volunteers. A high pressure liquid chromatographic method was used to analyse the 8 h urine samples collected after the administration of ... | http://www.ncbi.nlm.nih.gov/pubmed/17094172 | Effects of water extract of Hibiscus sabdariffa, Linn (Malvaceae) 'Roselle' on excretion of a diclofenac formulation. The effect of beverages prepared from the dried calyx of the flowers of Hibiscus sabdariffa on the excretion of diclofenac was investigated using a controlled study in healthy human volunteers. A high p... |
MED-714 | Towards prevention of vitamin D deficiency and beyond: knowledge gaps and research needs in vitamin D nutrition and public health. | The North American Institute of Medicine (IOM) recently published their report on dietary reference intakes (DRI) for Ca and vitamin D. The DRI committee's deliberations underpinning this most comprehensive report on vitamin D nutrition to date benefited hugely from a much expanded knowledge base in vitamin D over the ... | http://www.ncbi.nlm.nih.gov/pubmed/22017772 | Towards prevention of vitamin D deficiency and beyond: knowledge gaps and research needs in vitamin D nutrition and public health. The North American Institute of Medicine (IOM) recently published their report on dietary reference intakes (DRI) for Ca and vitamin D. The DRI committee's deliberations underpinning this m... |
MED-716 | VITAMIN D: A D-LIGHTFUL SOLUTION FOR HEALTH | Throughout evolution sunlight produced vitamin D in the skin has been critically important for health. Vitamin D, known as the sunshine vitamin, is actually a hormone. Once it is produced in the skin or ingested from the diet it is converted sequentially in the liver and kidneys to its biologically active form 1,25-dih... | http://www.ncbi.nlm.nih.gov/pubmed/21415774 | VITAMIN D: A D-LIGHTFUL SOLUTION FOR HEALTH Throughout evolution sunlight produced vitamin D in the skin has been critically important for health. Vitamin D, known as the sunshine vitamin, is actually a hormone. Once it is produced in the skin or ingested from the diet it is converted sequentially in the liver and kidn... |
MED-717 | Fructose intake at current levels in the United States may cause gastrointestinal distress in normal adults. | OBJECTIVE: Fructose intake has increased considerably in the United States, primarily as a result of increased consumption of high-fructose corn syrup, fruits and juices, and crystalline fructose. The purpose was to determine how often fructose, in amounts commonly consumed, would result in malabsorption and/or symptom... | http://www.ncbi.nlm.nih.gov/pubmed/16183355 | Fructose intake at current levels in the United States may cause gastrointestinal distress in normal adults. OBJECTIVE: Fructose intake has increased considerably in the United States, primarily as a result of increased consumption of high-fructose corn syrup, fruits and juices, and crystalline fructose. The purpose wa... |
MED-718 | The relation of passage of gas an abdominal bloating to colonic gas production. | OBJECTIVE: To determine the relation of gas passage and abdominal bloating to the production of gas in the colon. DESIGN: Randomized, double-blind, crossover study of gaseous symptoms during a 1-week period. SETTING: A Veterans Affairs medical center. PARTICIPANTS: 25 healthy medical center employees. INTERVENTION: Par... | http://www.ncbi.nlm.nih.gov/pubmed?term=8554251 | The relation of passage of gas an abdominal bloating to colonic gas production. OBJECTIVE: To determine the relation of gas passage and abdominal bloating to the production of gas in the colon. DESIGN: Randomized, double-blind, crossover study of gaseous symptoms during a 1-week period. SETTING: A Veterans Affairs medi... |
MED-719 | Flatulence--causes, relation to diet and remedies. | In addition to causing embarrassment and unease, flatulence is linked to a variety of symptoms, some of which may be distressing. This review describes the origins of intestinal gas, its composition and methods which have been developed for its analysis. Emphasis is placed upon the effects of legumes in the diet in pro... | http://www.ncbi.nlm.nih.gov/pubmed/3068547 | Flatulence--causes, relation to diet and remedies. In addition to causing embarrassment and unease, flatulence is linked to a variety of symptoms, some of which may be distressing. This review describes the origins of intestinal gas, its composition and methods which have been developed for its analysis. Emphasis is pl... |
MED-720 | The effect of oral alpha-galactosidase on intestinal gas production and gas-related symptoms. | Bloating, abdominal distention, and flatulence represent very frequent complaints in functional disorders but their pathophysiology and treatment are largely unknown. Patients frequently associate these symptoms with excessive intestinal gas and the reduction of gas production may represent an effective strategy. The a... | http://www.ncbi.nlm.nih.gov/pubmed/17151807 | The effect of oral alpha-galactosidase on intestinal gas production and gas-related symptoms. Bloating, abdominal distention, and flatulence represent very frequent complaints in functional disorders but their pathophysiology and treatment are largely unknown. Patients frequently associate these symptoms with excessive... |
MED-721 | Bismuth therapy in gastrointestinal diseases. | Bismuth therapy has shown efficacy against two major gastrointestinal disorders: peptic ulcer disease and diarrhea. In peptic ulcer disease it is as effective as the H2-receptor antagonists, costs considerably less, and offers a lower rate of relapse. When Helicobacter pylori is implicated, bismuth acts as an antimicro... | http://www.ncbi.nlm.nih.gov/pubmed/2199292 | Bismuth therapy in gastrointestinal diseases. Bismuth therapy has shown efficacy against two major gastrointestinal disorders: peptic ulcer disease and diarrhea. In peptic ulcer disease it is as effective as the H2-receptor antagonists, costs considerably less, and offers a lower rate of relapse. When Helicobacter pylo... |
MED-722 | An understanding of excessive intestinal gas. | Complaints of "excessive gas" from patients are very common but are difficult, if not impossible, for the physician to document. This review addresses the pathophysiology and management of such complaints, looking at the sources and routes of elimination, excessive eructation, bloating, and distention. In addition, com... | http://www.ncbi.nlm.nih.gov/pubmed/10998670 | An understanding of excessive intestinal gas. Complaints of "excessive gas" from patients are very common but are difficult, if not impossible, for the physician to document. This review addresses the pathophysiology and management of such complaints, looking at the sources and routes of elimination, excessive eructati... |
MED-723 | Effectiveness of devices purported to reduce flatus odor. | OBJECTIVE: A variety of charcoal-containing devices are purported to minimize problems with odoriferous rectal gas; however, the evidence supporting the efficacy of these products is virtually all anecdotal. We objectively evaluated the ability of these devices to adsorb two malodorous, sulfide gases (hydrogen sulfide ... | http://www.ncbi.nlm.nih.gov/pubmed/15667499 | Effectiveness of devices purported to reduce flatus odor. OBJECTIVE: A variety of charcoal-containing devices are purported to minimize problems with odoriferous rectal gas; however, the evidence supporting the efficacy of these products is virtually all anecdotal. We objectively evaluated the ability of these devices ... |
MED-724 | Flatulence--causes, relation to diet and remedies. | In addition to causing embarrassment and unease, flatulence is linked to a variety of symptoms, some of which may be distressing. This review describes the origins of intestinal gas, its composition and methods which have been developed for its analysis. Emphasis is placed upon the effects of legumes in the diet in pro... | http://www.ncbi.nlm.nih.gov/pubmed?term=3068547 | Flatulence--causes, relation to diet and remedies. In addition to causing embarrassment and unease, flatulence is linked to a variety of symptoms, some of which may be distressing. This review describes the origins of intestinal gas, its composition and methods which have been developed for its analysis. Emphasis is pl... |
MED-726 | Association of Alzheimer disease pathology with abnormal lipid metabolism: the Hisayama Study. | OBJECTIVE: The relationship between lipid profiles and Alzheimer disease (AD) pathology at the population level is unclear. We searched for evidence of AD-related pathologic risk of abnormal lipid metabolism. METHODS: This study included brain specimens from a series of 147 autopsies performed between 1998 and 2003 of ... | http://www.ncbi.nlm.nih.gov/pubmed/21911734 | Association of Alzheimer disease pathology with abnormal lipid metabolism: the Hisayama Study. OBJECTIVE: The relationship between lipid profiles and Alzheimer disease (AD) pathology at the population level is unclear. We searched for evidence of AD-related pathologic risk of abnormal lipid metabolism. METHODS: This st... |
MED-727 | Illuminating the 'black box'. A description of 4454 patient visits to 138 family physicians. | BACKGROUND: The content and context of family practice outpatient visits have never been fully described, leaving many aspects of family practice in a "black box," unseen by policymakers and understood only in isolation. This article describes community family practices, physicians, patients, and outpatient visits. MET... | http://www.ncbi.nlm.nih.gov/pubmed/9597995 | Illuminating the 'black box'. A description of 4454 patient visits to 138 family physicians. BACKGROUND: The content and context of family practice outpatient visits have never been fully described, leaving many aspects of family practice in a "black box," unseen by policymakers and understood only in isolation. This a... |
MED-728 | Barriers to providing nutrition counseling cited by physicians: a survey of primary care practitioners. | In a 1995 pivotal study, Kushner described the attitudes, practice behaviors, and barriers to the delivery of nutrition counseling by primary care physicians. This article recognized nutrition and dietary counseling as key components in the delivery of preventive services by primary care physicians. Kushner called for ... | http://www.ncbi.nlm.nih.gov/pubmed/20962310 | Barriers to providing nutrition counseling cited by physicians: a survey of primary care practitioners. In a 1995 pivotal study, Kushner described the attitudes, practice behaviors, and barriers to the delivery of nutrition counseling by primary care physicians. This article recognized nutrition and dietary counseling ... |
MED-729 | Transfer of spinal cord material to subsequent bovine carcasses at splitting. | During the slaughter process, cattle carcasses are split by sawing centrally down the vertebral column, resulting in contamination of each half with spinal cord material. Using a novel method based on a real-time PCR assay, we measured saw-mediated tissue transfer among carcasses. Up to 2.5% of the tissue recovered fro... | http://www.ncbi.nlm.nih.gov/pubmed/15453582 | Transfer of spinal cord material to subsequent bovine carcasses at splitting. During the slaughter process, cattle carcasses are split by sawing centrally down the vertebral column, resulting in contamination of each half with spinal cord material. Using a novel method based on a real-time PCR assay, we measured saw-me... |
MED-730 | Clinical herd health, farm management and antimicrobial resistance in Campylobacter coli on finishing pig farms in Switzerland. | The world-wide increase of antimicrobial resistance in micro-organisms complicates medical treatment of infected humans. We did a risk-factor analysis for the prevalence of antimicrobial resistant Campylobacter coli on 64 Swiss pig finishing farms. Between May and November 2001, 20 faecal samples per farm were collecte... | http://www.ncbi.nlm.nih.gov/pubmed/15907569 | Clinical herd health, farm management and antimicrobial resistance in Campylobacter coli on finishing pig farms in Switzerland. The world-wide increase of antimicrobial resistance in micro-organisms complicates medical treatment of infected humans. We did a risk-factor analysis for the prevalence of antimicrobial resis... |
MED-731 | Three rare cases of anthrax arising from the same source. | Anthrax is an acute bacterial infection caused by Bacillus anthracis. Humans become infected under natural conditions by contact with infected animals or contaminated animal products. About 95% of human anthrax is cutaneous and 5% respiratory. Gastrointestinal anthrax is very rare, and has been reported in less than 1%... | http://www.ncbi.nlm.nih.gov/pubmed/16442628 | Three rare cases of anthrax arising from the same source. Anthrax is an acute bacterial infection caused by Bacillus anthracis. Humans become infected under natural conditions by contact with infected animals or contaminated animal products. About 95% of human anthrax is cutaneous and 5% respiratory. Gastrointestinal a... |
MED-732 | Dissemination of central nervous system tissue during the slaughter of cattle in three Irish abattoirs. | Sponge samples were taken from the carcases, meat, personnel and surfaces involved in stunning, slaughter and dressing/boning activities at three abattoirs, and from retail beef products. The samples were examined for the presence of central nervous system (CNS)-specific proteins (syntaxin 1B and/or glial fibrillary ac... | http://www.ncbi.nlm.nih.gov/pubmed/14725425 | Dissemination of central nervous system tissue during the slaughter of cattle in three Irish abattoirs. Sponge samples were taken from the carcases, meat, personnel and surfaces involved in stunning, slaughter and dressing/boning activities at three abattoirs, and from retail beef products. The samples were examined fo... |
MED-733 | Amyloid arthropathy in chickens. | The present paper presents an overview of current knowledge of amyloid arthropathy in chickens, and covers the pathogenesis of amyloidosis in general and in birds, field cases reported, and the studies performed to assess the amyloidogenicity of various agents compared to that of Enterococcus faecalis. An animal model ... | http://www.ncbi.nlm.nih.gov/pubmed/10427631 | Amyloid arthropathy in chickens. The present paper presents an overview of current knowledge of amyloid arthropathy in chickens, and covers the pathogenesis of amyloidosis in general and in birds, field cases reported, and the studies performed to assess the amyloidogenicity of various agents compared to that of Entero... |
MED-734 | Susceptibility of the domestic duck (Anas platyrhynchos) to experimental infection with Toxoplasma gondii oocysts. | A total of 28 domestic ducks were divided into seven groups of four ducks. Six groups were inoculated per os with 10(1), 10(2), 10(3), 10(4), 10(5) and 10(5.7) oocysts Toxoplasma gondii oocysts (K21 strain, which is avirulent for mice), and the remaining group was used as a control. Antibodies to T. gondii were detecte... | http://www.ncbi.nlm.nih.gov/pubmed/15276981 | Susceptibility of the domestic duck (Anas platyrhynchos) to experimental infection with Toxoplasma gondii oocysts. A total of 28 domestic ducks were divided into seven groups of four ducks. Six groups were inoculated per os with 10(1), 10(2), 10(3), 10(4), 10(5) and 10(5.7) oocysts Toxoplasma gondii oocysts (K21 strain... |
MED-735 | Prevalence and incidence of gastroduodenal ulcers during treatment with vascular protective doses of aspirin. | BACKGROUND: Aspirin is valuable for preventing vascular events, but information about ulcer frequency is necessary to inform risk-benefit decisions in individual patients. AIM: To determine ulcer prevalence and incidence in a population representative of those given aspirin therapy and evaluate risk predictors. METHODS... | http://www.ncbi.nlm.nih.gov/pubmed/16225488 | Prevalence and incidence of gastroduodenal ulcers during treatment with vascular protective doses of aspirin. BACKGROUND: Aspirin is valuable for preventing vascular events, but information about ulcer frequency is necessary to inform risk-benefit decisions in individual patients. AIM: To determine ulcer prevalence and... |
MED-736 | Diverticular disease: Epidemiology and management | Diverticular disease of the colon is among the most prevalent conditions in western society and is among the leading reasons for outpatient visits and causes of hospitalization. While previously considered to be a disease primarily affecting the elderly, there is increasing incidence among individuals younger than 40 y... | http://www.ncbi.nlm.nih.gov/pubmed/21876861 | Diverticular disease: Epidemiology and management Diverticular disease of the colon is among the most prevalent conditions in western society and is among the leading reasons for outpatient visits and causes of hospitalization. While previously considered to be a disease primarily affecting the elderly, there is increa... |
MED-743 | Herbal medicines, other than St. John's Wort, in the treatment of depression: a systematic review. | OBJECTIVE: To evaluate herbal medicines, other than St. John's wort, in the treatment of depression. DATA SOURCES/SEARCH METHODS: A computer-based search of Medline, Cinahl, AMED, ALT Health Watch, Psych Articles, Psych Info, Current Contents databases, Cochrane Controlled Trials Register, and Cochrane Database of Syst... | http://www.ncbi.nlm.nih.gov/pubmed/21438645 | Herbal medicines, other than St. John's Wort, in the treatment of depression: a systematic review. OBJECTIVE: To evaluate herbal medicines, other than St. John's wort, in the treatment of depression. DATA SOURCES/SEARCH METHODS: A computer-based search of Medline, Cinahl, AMED, ALT Health Watch, Psych Articles, Psych I... |
MED-744 | Therapy with saffron and the goddess at Thera. | This paper presents a new interpretation of a unique Bronze Age (c. 3000-1100 BCE) Aegean wall painting in the building of Xeste 3 at Akrotiri,Thera. Crocus carturightianus and its active principle, saffron, are the primary subjects at Xeste 3. Several lines of evidence suggest that the meaning of these frescoes concer... | http://www.ncbi.nlm.nih.gov/pubmed/15259204 | Therapy with saffron and the goddess at Thera. This paper presents a new interpretation of a unique Bronze Age (c. 3000-1100 BCE) Aegean wall painting in the building of Xeste 3 at Akrotiri,Thera. Crocus carturightianus and its active principle, saffron, are the primary subjects at Xeste 3. Several lines of evidence su... |
MED-745 | The double-blind, randomized, placebo-controlled trial: gold standard or golden calf? | The double-blind randomized controlled trial (RCT) is accepted by medicine as objective scientific methodology that, when ideally performed, produces knowledge untainted by bias. The validity of the RCT rests not just on theoretical arguments, but also on the discrepancy between the RCT and less rigorous evidence (the ... | http://www.ncbi.nlm.nih.gov/pubmed/11377113 | The double-blind, randomized, placebo-controlled trial: gold standard or golden calf? The double-blind randomized controlled trial (RCT) is accepted by medicine as objective scientific methodology that, when ideally performed, produces knowledge untainted by bias. The validity of the RCT rests not just on theoretical a... |
MED-746 | Evaluation of Crocus sativus L. (saffron) on male erectile dysfunction: a pilot study. | In this study, the effect of Crocus sativus (saffron) was studied on male erectile dysfunction (ED). Twenty male patients with ED were followed for ten days in which each morning they took a tablet containing 200mg of saffron. Patients underwent the nocturnal penile tumescence (NPT) test and the international index of ... | http://www.ncbi.nlm.nih.gov/pubmed/19427775 | Evaluation of Crocus sativus L. (saffron) on male erectile dysfunction: a pilot study. In this study, the effect of Crocus sativus (saffron) was studied on male erectile dysfunction (ED). Twenty male patients with ED were followed for ten days in which each morning they took a tablet containing 200mg of saffron. Patien... |
MED-748 | Medical practice and social authority. | Questions of medical ethics are often treated as especially difficult casuistical problems or as difficult cases illustrative of paradoxes or advantages in global moral theories. I argue here, in opposition to such approaches, for the inseparability of questions of social history and social theory from any normative as... | http://www.ncbi.nlm.nih.gov/pubmed/8899540 | Medical practice and social authority. Questions of medical ethics are often treated as especially difficult casuistical problems or as difficult cases illustrative of paradoxes or advantages in global moral theories. I argue here, in opposition to such approaches, for the inseparability of questions of social history ... |
MED-749 | Current perception of nutrition education in U.S. medical schools. | Historically, physicians have perceived the quality of nutrition training during medical school as inadequate. A literature review suggests that this perception has not significantly changed since the 1950s. Many schools have worked to create clinical nutrition curricula for use during medical school. Interestingly, da... | http://www.ncbi.nlm.nih.gov/pubmed/21597916 | Current perception of nutrition education in U.S. medical schools. Historically, physicians have perceived the quality of nutrition training during medical school as inadequate. A literature review suggests that this perception has not significantly changed since the 1950s. Many schools have worked to create clinical n... |
MED-751 | Dietary Fat and Cholesterol and Risk of Cardiovascular Disease in Older Adults: the Health ABC Study | BACKGROUND AND AIMS Although dietary fats and cholesterol have previously been associated with risk of cardiovascular disease (CVD) in middle aged populations, less is known among older adults. The purpose of this study was to determine the association between dietary fats, cholesterol, and eggs and CVD risk among comm... | http://www.ncbi.nlm.nih.gov/pubmed/20338738 | Dietary Fat and Cholesterol and Risk of Cardiovascular Disease in Older Adults: the Health ABC Study BACKGROUND AND AIMS Although dietary fats and cholesterol have previously been associated with risk of cardiovascular disease (CVD) in middle aged populations, less is known among older adults. The purpose of this study... |
MED-752 | Phytoestrogens and their low dose combinations inhibit mRNA expression and activity of aromatase in human granulosa-luteal cells. | There is evidence that certain phytoestrogens inhibit aromatase, the enzyme that converts androgens to oestrogens. Kinetic studies in cell-free preparations show that they may inhibit aromatase by competitive binding to the enzyme, but there is a paucity of studies investigating longer-term effects of phytoestrogens on... | http://www.ncbi.nlm.nih.gov/pubmed/16965912 | Phytoestrogens and their low dose combinations inhibit mRNA expression and activity of aromatase in human granulosa-luteal cells. There is evidence that certain phytoestrogens inhibit aromatase, the enzyme that converts androgens to oestrogens. Kinetic studies in cell-free preparations show that they may inhibit aromat... |
MED-753 | Estrogen levels in nipple aspirate fluid and serum during a randomized soy trial | Background Based on the hypothesized protective effect, we examined the effect of soy foods on estrogens in nipple aspirate fluid (NAF) and serum, possible indicators of breast cancer risk. Methods In a cross-over design, we randomized 96 women who produced ≥10 μL NAF to a high- or low-soy diet for 6-months. During the... | http://www.ncbi.nlm.nih.gov/pubmed/21742946 | Estrogen levels in nipple aspirate fluid and serum during a randomized soy trial Background Based on the hypothesized protective effect, we examined the effect of soy foods on estrogens in nipple aspirate fluid (NAF) and serum, possible indicators of breast cancer risk. Methods In a cross-over design, we randomized 96 ... |
MED-754 | Effect of a dietary portfolio of cholesterol-lowering foods given at 2 levels of intensity of dietary advice on serum lipids in hyperlipidemia: a r... | CONTEXT: Combining foods with recognized cholesterol-lowering properties (dietary portfolio) has proven highly effective in lowering serum cholesterol under metabolically controlled conditions. OBJECTIVE: To assess the effect of a dietary portfolio administered at 2 levels of intensity on percentage change in low-densi... | http://www.ncbi.nlm.nih.gov/pubmed/21862744 | Effect of a dietary portfolio of cholesterol-lowering foods given at 2 levels of intensity of dietary advice on serum lipids in hyperlipidemia: a r... CONTEXT: Combining foods with recognized cholesterol-lowering properties (dietary portfolio) has proven highly effective in lowering serum cholesterol under metabolicall... |
MED-756 | Diet-related telomere shortening and chromosome stability | Recent evidences have highlighted an influence of micronutrients in the maintenance of telomere length (TL). In order to explore whether diet-related telomere shortening had any physiological relevance and was accompanied by significant damage in the genome, in the present study, TL was assessed by terminal restriction... | http://www.ncbi.nlm.nih.gov/pubmed?term=21857007 | Diet-related telomere shortening and chromosome stability Recent evidences have highlighted an influence of micronutrients in the maintenance of telomere length (TL). In order to explore whether diet-related telomere shortening had any physiological relevance and was accompanied by significant damage in the genome, in ... |
MED-757 | Turning back the clock: adopting a healthy lifestyle in middle age. | PURPOSE: To determine the frequency of adopting a healthy lifestyle (5 or more fruits and vegetables daily, regular exercise, BMI 18.5-29.9 kg/m2, no current smoking) in a middle-aged cohort, and determine the subsequent rates of cardiovascular disease (CVD) and mortality among those who adopt a healthy lifestyle. METH... | http://www.ncbi.nlm.nih.gov/pubmed?term=17602933 | Turning back the clock: adopting a healthy lifestyle in middle age. PURPOSE: To determine the frequency of adopting a healthy lifestyle (5 or more fruits and vegetables daily, regular exercise, BMI 18.5-29.9 kg/m2, no current smoking) in a middle-aged cohort, and determine the subsequent rates of cardiovascular disease... |
MED-758 | Low-Risk Lifestyle Behaviors and All-Cause Mortality: Findings From the National Health and Nutrition Examination Survey III Mortality Study | Objectives. We examined the relationship between 4 low-risk behaviors—never smoked, healthy diet, adequate physical activity, and moderate alcohol consumption—and mortality in a representative sample of people in the United States. Methods. We used data from 16958 participants aged 17 years and older in the National He... | http://www.ncbi.nlm.nih.gov/pubmed/21852630 | Low-Risk Lifestyle Behaviors and All-Cause Mortality: Findings From the National Health and Nutrition Examination Survey III Mortality Study Objectives. We examined the relationship between 4 low-risk behaviors—never smoked, healthy diet, adequate physical activity, and moderate alcohol consumption—and mortality in a r... |
MED-759 | Associations of dietary dark-green and deep-yellow vegetables and fruits with cervical intraepithelial neoplasia: modification by smoking. | Smoking has been positively and fruit and vegetable intake has been negatively associated with cervical cancer, the second most common cancer among women worldwide. However, a lower consumption of fruits and reduced serum carotenoids have been observed among smokers. It is not known whether the smoking effect on the ri... | http://www.ncbi.nlm.nih.gov/pubmed/21092390 | Associations of dietary dark-green and deep-yellow vegetables and fruits with cervical intraepithelial neoplasia: modification by smoking. Smoking has been positively and fruit and vegetable intake has been negatively associated with cervical cancer, the second most common cancer among women worldwide. However, a lower... |
MED-760 | A High Antioxidant Spice Blend Attenuates Postprandial Insulin and Triglyceride Responses and Increases Some Plasma Measures of Antioxidant Activity in Healthy, Overweight Men | There is much interest in the potential of dietary antioxidants to attenuate in vivo oxidative stress, but little characterization of the time course of plasma effects exists. Culinary spices have demonstrated potent in vitro antioxidant properties. The objective of this study was to examine whether adding 14 g of a hi... | http://www.ncbi.nlm.nih.gov/pubmed/21697300 | A High Antioxidant Spice Blend Attenuates Postprandial Insulin and Triglyceride Responses and Increases Some Plasma Measures of Antioxidant Activity in Healthy, Overweight Men There is much interest in the potential of dietary antioxidants to attenuate in vivo oxidative stress, but little characterization of the time c... |
MED-761 | The counseling practices of internists. | OBJECTIVES: To determine the counseling practices of a group of internists in the areas of smoking, exercise, and alcohol and seat belt use, and to determine the associations among physicians' personal health habits and their counseling practices. DESIGN: A random stratified sample of members and fellows of the America... | http://www.ncbi.nlm.nih.gov/pubmed/1983933 | The counseling practices of internists. OBJECTIVES: To determine the counseling practices of a group of internists in the areas of smoking, exercise, and alcohol and seat belt use, and to determine the associations among physicians' personal health habits and their counseling practices. DESIGN: A random stratified samp... |
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