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gen_319400789f36e14f943645377a9ea342 | Erlotinib Study for Myelodysplastic Syndrome (MDS) | Genentech, Inc. | H. Lee Moffitt Cancer Center and Research Institute | NCT00977548 |
The purpose of this research study is to find out what effects, good and/or bad, erlotinib
has on the patient and their myelodysplastic syndrome. Erlotinib has been approved by the
Food and Drug Administration (FDA) to treat non-small cell lung cancer; however, erlotinib
use in this study is co... | Drug | 4other_research_funding |
gen_987ebce3c515381f60d4ce0833dc7f2c | Tomosynthesis Versus Digital Mammography in a Population-based Screening Program | im3D S.p.A. | SCDO Epidemiologia dei Tumori, AOU Città della Salute e della Scienza di Torino | NCT02590315 |
Preliminary results from prospective screening trials show that Digital Breast Tomosynthesis
(DBT) is more sensitive and more specific than conventional digital mammography (DM).
However, large randomised controlled trials (RCTs) are needed to confirm these promising
results. Furthermore, poten... | Other | 4other_research_funding |
gen_3657caa9dc6f1068b88c52adef8a37cd | Azithromycin - Ivermectin Mass Drug Administration for Skin Disease | Murdoch Childrens Research Institute | London School of Hygiene and Tropical Medicine | NCT02775617 |
This is an open-label prospective community intervention trial to assess the impact of
community mass treatment with azithromycin for yaws and ivermectin for scabies, on non-yaws
bacterial skin infections.
Communities will be randomised to receive standard treatment for both yaws and scabies e... | Drug | 4other_research_funding |
gen_78c9a575ced9413ecc785a01dbcc7bb0 | Evaluation of 4 New Simplified Antiretroviral Treatments in Naive HIV-1 Infected Patients in Africa (ANRS 12115 DAYANA) | Merck Sharp & Dohme Corp. | Hopital de Fann, Dakar | NCT00573001 |
The goal of this trial is to demonstrate that new treatments are as effective as a reference
triple-agent regimen in driving plasma viral load below the detection limit early during
treatment (16 weeks). These simplified treatments involve fewer tablets and intakes,
fixed-dose combinations, and... | Drug | 4other_research_funding |
gen_889975a7b33189315c7ed6285cd32c62 | Antiarrhythmics or Ablation for Ventricular Tachycardia Pilot | St. Jude Medical | Nova Scotia Health Authoriry | NCT02830360 |
This is a pilot study to determine the feasibility of a larger scale multicenter trial
comparing first line catheter ablation to antiarrhythmic drug therapy for patients with prior
MI, an ICD and VT.
| Drug | 4other_research_funding |
gen_c905972bed428ccc3c6d0a317b8dd9cb | INtegrating DEPrEssioN and Diabetes treatmENT (INDEPENDENT) Study | National Institute of Mental Health (NIMH) | Dr Mohan's Diabetes Specialities Clinic | NCT02022111 |
To provide better care and preventive services for people with both depression and diabetes,
the investigators propose to develop and test whether interventions to reduce depressive
symptoms can be integrated into routine diabetes clinics in India. The investigators will
gather feedback from pa... | Other | 4other_research_funding |
gen_8f3aff4316d8464a3e9039f6723db1aa | Atorvastatin in New Onset Type 1 Diabetes Mellitus (T1DM) | FDA Office of Orphan Products Development | Children's Hospital of Philadelphia | NCT00529191 |
The goal of this application is to evaluate the safety and efficacy of atorvastatin as a
potential treatment to preserve beta cell function in children and young adults with newly
diagnosed type 1 diabetes (T1DM).
| Drug | 4other_research_funding |
gen_192796cbefa55e578aeeb1cacdcbc744 | Primary Tube Versus Trabeculectomy Study | Research to Prevent Blindness | Bascom Palmer Eye Institute | NCT00666237 |
The purpose of the Primary Tube Versus Trabeculectomy (PTVT) Study is to compare the
long-term safety and efficacy of nonvalved tube shunt surgery to trabeculectomy with
mitomycin C in eyes that have not had previous ocular surgery.
| Procedure | 4other_research_funding |
gen_807075b2ae303368b8158fdea01d9ca6 | A Trial of Negative Ion Generation Versus Light-Emitting Diode Phototherapy for Seasonal Affective Disorder (SAD) | Clinical Associates Research, Maryland | Yale University | NCT00809523 |
This is a randomized, controlled clinical trial of inactivated negative ion generation or
light-emitting photodiode therapy for Seasonal Affective Disorder (SAD, winter depression),
for subjects with a DSM IV diagnosis of Major Depression, with Seasonal Pattern, Winter type,
to examine efficacy... | Device | 4other_research_funding |
gen_e1687248fafc1deb55f80f038b4897e3 | PEG-Interferon Alfa-2b in Treating Patients With Stage IV Melanoma | National Cancer Institute (NCI) | Gundersen Lutheran Center for Cancer and Blood | NCT00049530 |
RATIONALE: Peginterferon (PEG-interferon) alfa-2b may stop the growth of cancer by stopping
blood flow to the tumor.
PURPOSE: Phase II trial to study the effectiveness of PEG-interferon alfa-2b in treating
patients who have stage IV melanoma.
| Biological | 4other_research_funding |
gen_72b809c8bc8150b6a0ebc7cd1927131a | Task Shifting and Blood Pressure Control in Ghana | National Heart, Lung, and Blood Institute (NHLBI) | NYU Langone Medical Center | NCT01802372 |
The goal of this study is to evaluate the comparative effectiveness of the World Health
Organization Package targeted at Cardiovascular (CV) risk assessment and hypertension
control, delivered by Community Health Nurses as part of Ghana's Community based Health
Planning and Services program, ve... | Behavioral | 4other_research_funding |
gen_b240e0cd88f2c928908b4fd7c687e689 | Safety/Efficacy Study to Assess Whether FVIII/VWF Concentrate Can Induce Immune Tolerance in Haemophilia A Patients | Sintesi Research Srl | Centro Emofilia e Trombosi Angela Bianchi Bonomi, IRCCS Fondazione Ospedale Maggiore Policlinico | NCT02479087 |
The purpose of this study is to assess the role of a FVIII/VWF complex concentrate (Emoclot)
in successfully inducing immune tolerance (I.T.I.) in patients with Haemophilia A with
inhibitors, including patients at high risk of failure.
| Drug | 4other_research_funding |
gen_b3d178e83a83b628e041daa836db604c | The Safety and Efficacy of Low and High Carbohydrate Diets | National Center for Complementary and Integrative Health (NCCIH) | University of Pennsylvania | NCT00143936 |
This study will compare the safety and effectiveness of a low carbohydrate diet (Atkins Diet)
with a high carbohydrate diet (conventional USDA diet).
| Behavioral | 4other_research_funding |
gen_63a78b3e0a96b063e2205a8015df3160 | Self-Management Program Based on Physical Exercises in People With Multiple Sclerosis | CHU de Reims | UCL | NCT02607020 |
Fatigue is the most chronic and disabling symptom in multiple sclerosis patients.
Self-management physical exercise programs seem promising to allow patients to improve their
fatigue and their deconditioning. However, the effectiveness of such programs has been poorly
assessed until now. The ob... | Other | 4other_research_funding |
gen_6d140173c85ab7ea415deababdc9c179 | AZD2171 and Temsirolimus in Patients With Advanced Gynecological Malignancies | Massachusetts General Hospital | Dana-Farber Cancer Institute | NCT01065662 |
The purpose of this research study is to determine the safety of the combination of the two
drugs cediranib and temsirolimus and the highest doses of these two drugs that can be given
in combination to people safely. Cediranib is a drug that may stop blood supply to the tumor
and therefore help... | Drug | 4other_research_funding |
gen_8f698e459e6126c143532c96a018312a | OSTPRE-Fracture Prevention Study | Academy of Finland | Department of Gynecology and Obstetrics, University Hospital of Kuopio | NCT00592917 |
The purpose of this study is to determine the effect of calcium 1000 mg/d and vitamin-D3 800
IU/d divided in two daily doses on the incidence of falls and fractures, bone mineral density
and bone metabolism in postmenopausal women 65-71 years of age.
| Dietary Supplement | 4other_research_funding |
gen_8daaec2b4bacaa9e1cd913b0c514473e | Beat AML Core Study | Cellworks Group Inc. | University of Florida | NCT02927106 |
In this study, DNA sequencing, computational biology modeling, and ex vivo drug sensitivity
assays will be utilized to define clinically relevant gene mutations and identify potential
therapeutics for patients with acute myeloid leukemia (AML).
| Genetic | 4other_research_funding |
gen_396bed29a83599f50836cde73c12448f | The Medicines Optimisation Review Toolkit Evaluation in HIV Outpatients | Merck Sharp & Dohme Corp. | University of Sussex | NCT03340077 |
Multicentre, randomised (1:1), controlled, open (not blinded) comparison of MOR toolkit
(intervention) with standard pharmaceutical care (control)
| Other | 4other_research_funding |
gen_2907d6bf09c3ba5d65e0d5f71b752c37 | Induction Chemotherapy in Patients With Locoregionally Advanced Nasopharyngeal Carcinoma | Jiangxi Provincial Cancer Hospital | Sun Yat-sen University | NCT01245959 |
The purpose of this study is to compare induction chemotherapy
(docetaxel+cisplatin+fluorouracil) plus concurrent chemoradiotherapy with concurrent
chemoradiotherapy in patients with locoregionally advanced nasopharyngeal carcinoma (NPC), in
order to confirm the value of induction chemotherapy ... | Radiation | 4other_research_funding |
gen_3ecbd378ac88fef9c8a4a0dd22c18c64 | Progressive Goal Attainment Program for Veterans | Michael Debakey Veterans Affairs Medical Center | MDRC | NCT01565863 |
The purpose of this study is to test the effectiveness of the Progressive Goal Attainment
Program (PGAP) in improving employment outcomes and community engagement among U.S. veterans
with disabilities.
| Behavioral | 4other_research_funding |
gen_46a9a29b684478ef1cf9441111a2d48d | Laparotomy vs. Drainage for Infants With Necrotizing Enterocolitis | National Center for Research Resources (NCRR) | Stanford University | NCT01029353 |
This trial will compare the effectiveness of two surgical procedures -laparotomy versus
drainage - commonly used to treat necrotizing enterocolitis (NEC) or isolated intestinal
perforations (IP) in extremely low birth weight infants (≤1,000 g). Infants diagnosed with
NEC or IP requiring surgica... | Procedure | 4other_research_funding |
gen_463beaa30a40cd522ab7ef14788d9383 | Cognitive De-Biasing and the Assessment of Pediatric Bipolar Disorder | North Carolina Translational and Clinical Sciences Institute | University of North Carolina, Chapel Hill | NCT01799291 |
The primary aim is to test the efficacy of a new intervention to improve clinical judgment.
The investigators focus on the assessment of pediatric bipolar disorder (PBD), a
controversial diagnosis with frequent diagnostic errors, by educating mental health
professionals in common cognitive pitf... | Behavioral | 4other_research_funding |
gen_b35bd00d942fc230bed640996ede34e3 | AZD4547 & Anastrozole or Letrozole (NSAIs) in ER+ Breast Cancer Patients Who Have Progressed on NSAIs (RADICAL) | Cancer Research UK | Burton Hospitals NHS Foundation Trust | NCT01791985 |
This study is looking at a new drug called AZD4547 which is being tested for the treatment of
oestrogen receptor positive breast cancer. AZD4547 is a drug which specifically "blocks"
proteins called fibroblast growth factor receptors (FGFR1) that are involved in the processes
that help cancer c... | Drug | 4other_research_funding |
gen_bd93d2e39ad04b7c0cedf75571905084 | Standard Drug Therapy vs. Implanted Defibrillator for Primary Prevention of Sudden Cardiac Death | Ontario Ministry of Health and Long Term Care | St. Michael's Hospital, Toronto | NCT00524862 |
Recent ACC/AHA/ESC guidelines recommend prophylactic ICD implantation in most patients with
coronary heart disease and LVEF < 40%. Current Canadian guidelines recommend ICDs for primary
prophylaxis in CAD patients with LVEF < 30% (Class I recommendation). There are very sparse
data to recommend... | Drug | 4other_research_funding |
gen_bf5a7c56d1b5dc2f8f18de068046a3fa | IRIS : Use of Implantable Defibrillator in High-Risk Patients Early After Acute Myocardial Infarction | AstraZeneca | Herzzentrum Ludwigshafen, Germany | NCT00157768 |
Of the patients who survive hospitalization after an acute myocardial infarction, ca. 10% die
of sudden cardiac death in the following 2 years. The prognosis appears not improved by
medication with antiarrhythmics (class I/III). A positive effect of beta-blockers (Metoprolol
CR/Zok) on total mo... | Device | 4other_research_funding |
gen_57eb6850fe8591225571812767a5bbaa | Brain Response to Single Dose of Pregabalin in Fibromyalgia | Coordenação de Aperfeiçoamento de Pessoal de Nível Superior. | HCPA | NCT02639533 |
Fibromyalgia syndrome represents a "spectrum disorder" characterized by widespread chronic
pain, fatigue, sleep disturbances, mood and cognitive alterations. The most accepted models
explaining the causes of the disease have focused on the reduced pain inhibitory systems
activity, that allow lo... | Drug | 4other_research_funding |
gen_826fc3ed446e81a9ff58d19a7d7274a1 | Intestinal Remodeling And Reprogramming of Glucose Metabolism Following Laparoscopic Roux-en-Y Gastric Bypass | Society of American Gastrointestinal and Endoscopic Surgeons | Duke University | NCT02288351 |
The purpose of this study is to investigate small intestinal remodeling and reprogramming of
glucose metabolism in patients with Type 2 Diabetes Mellitus (T2DM) who undergo laparoscopic
Roux-en-Y Gastric Bypass (RYGB). Our specific goal is to determine if the gene and protein
expression levels ... | Other | 4other_research_funding |
gen_424254aa7a102f122f94a54aa3d1cd3c | Efficacy and Safety of Nipent, Cytoxan and Rituxan in the Treatment of Chronic Lymphocytic Leukemia. | Mena, Raul, M.D. | East Valley Hematology and Oncology Group | NCT00131313 |
This research study measures the safety and efficacy of the combination of three drugs that
are approved, Nipent, Rituxan and Cytoxan in the treatment of Chronic Lymphocytic Leukemia
(CLL). These drugs are being given together for investigational purposes as the specific
combination of these th... | Drug | 4other_research_funding |
gen_e4c6cacc873ab83900cec09d16edace5 | BATTLE-FL: Front-Line Biomarker-Integrated Treatment Study in Non Small Cell Lung Cancer | ImClone LLC | M.D. Anderson Cancer Center | NCT01263782 |
The goal of this clinical research study is to learn if knowing biomarker status can help
researchers find better treatment combinations for patients with advanced NSCLC.
Researchers want to use biomarker status to decide what drug (bevacizumab, or cixutumumab) to
give in combination with carb... | Drug | 4other_research_funding |
gen_d5e48c4eabfcb5570e12fc644de53002 | A Phase II Study of Spinal Radiosurgery | The Kirklin Clinic at Acton Road | University of Alabama at Birmingham | NCT00573872 |
Phase I of the study (motion and quality assurance [QA] study) is being used to determine
intrafraction target motion and define quality assurance procedures for single fraction
spinal radiosurgery. The Phase II portion of the study is being used to estimate the
palliative response (pain or rel... | Radiation | 4other_research_funding |
gen_c21581f87e6a87739e77a5948d844c3d | Study to Evaluate Effects of Investigational Drug on Oxygenation in Healthy Volunteers Under Hypoxic Conditions | Mayo Clinic | Global Blood Therapeutics | NCT03051711 |
To evaluate the effect of GBT440 on oxygen saturation at rest and exercise, under hypoxic
conditions, at Day 15 compared to Baseline.
| Drug | 4other_research_funding |
gen_6b4a7c0787e993e21cbb782610fb61f6 | Feeding the Critically Ill During Phases of Altered Redox Status | American Society for Parenteral and Enteral Nutrition | University of Illinois at Chicago | NCT03085615 |
The FEDOX trial is a prospective randomized clinical trial exploring oxidative stress as a
mechanism of harm to explain the negative outcomes found in feeding trials that achieved
caloric exposure commensurate with the nationally recommended guidelines. Due to its impact
on energy metabolism, w... | Other | 4other_research_funding |
gen_dbc7049325efeab5cd71fe1b8029b626 | Comparison of Intrathecal Morphine With the Quadratus Lumborum Type 2 Block for Post-operative Analgesia Following Elective Caesarean Section (QLBvITM Study) | Sunshine Coast Hospital and Health Service | Sunshine Coast University Hospital | NCT03267628 |
The investigators are comparing post operative analgesia provided for caesarean section
patients, with the quadratus lumborum type 2 block and intrathecal morphine.
| Procedure | 4other_research_funding |
gen_8579417862b193ced69ee50862c284bf | Tolerability, Safety and Pharmacokinetic Study Of Mianhuahua Flavonoids Tablets in Healthy Adult Subjects | Chinese Academy of Sciences | Shuguang Hospital affiliated with Shanghai University of TCM | NCT02622230 |
The purpose of this study is to determine the safety and tolerability, and to evaluate the
pharmacokinetic characteristics of Mianhuahua Flavonoids Tablets after oral administration in
healthy adult subjects.
| Drug | 4other_research_funding |
gen_8c48f4a8cb03b415bbdb3303bdbda575 | Chemotherapy and Radiation Therapy With or Without Surgery in Treating Patients With Head and Neck Cancer | National Cancer Institute (NCI) | CHUM Hospital Notre Dame | NCT00047008 |
RATIONALE: Radiation therapy (RT) uses high-energy x-rays to damage tumor cells. Giving
radiation therapy in different ways and combining it with chemotherapy before surgery may
kill more tumor cells. It is not yet known which radiation therapy regimen combined with
chemotherapy with or without... | Radiation | 4other_research_funding |
gen_9be3b6ecb0891715462c857dfc07f00d | Cadiotocography Combined With ST-analysis Versus Cardiotocography Combined With Scalp-pH | ElsassFonden | Copenhagen University, Denmark | NCT01699646 |
Hypothesis:
STAN monitoring will reduce the number of interventions because of suspected fetal asphyxia
and reduce the number of newborns with metabolic acidosis.
Primary endpoint:
1) Frequency of metabolic acidosis in the two groups, defined by pH in umbilical cord artery
< 7.05... | Procedure | 4other_research_funding |
gen_fabea028caca02fa747d2033486ba4bf | A Bridge to Treatment: The Therapeutic Workplace and Methadone Treatment | National Institute on Drug Abuse (NIDA) | Professor, Johns Hopkins University School of Medicine | NCT01416584 |
The purpose of this study is to evaluate the effectiveness of the Therapeutic Workplace in
promoting methadone treatment and increasing abstinence in unemployed, out-of-treatment
injection heroine users.
| Behavioral | 4other_research_funding |
gen_3396634acfe826a0f42f9998f64c71ac | Evaluation of SQ109, High-dose Rifampicin, and Moxifloxacin in Adults With Smear-positive Pulmonary TB in a MAMS Design | Medical Research Council | Klinikum of the University of Munich | NCT01785186 |
This study is a multiple-arm, multiple-stage (MAMS), phase 2, open label, randomized,
controlled clinical trial that will compare the efficacy and safety of four experimental four
drug regimens with a standard control regimen in patients with smear positive, pulmonary
tuberculosis (TB). Patient... | Drug | 4other_research_funding |
gen_227371bf2ad0bda2a4de4c276ac7dafb | DGB-01 Effects on Endurance Exercise | Immunotec Inc. | University of Kentucky, Dept of Physiology | NCT01424904 |
The purpose of this research is to evaluate the effects of DGB-01 on performance of a 40‐km
time trial in trained male cyclists. The investigators believe that DGB-01 will improve
performance on the time trial as measured by a reduction in the amount of time required to
complete the distance, u... | Dietary Supplement | 4other_research_funding |
gen_c858d95de61dfbdd4fcb2dd6bcac61f3 | Meta-analyses of the Effect of Sucrose Versus High Fructose Corn Syrup on Cardiometabolic Risk | The Physicians' Services Incorporated Foundation | University of Toronto | NCT02702479 |
The rise in high fructose corn syrup (HFCS) consumption over the past 40 years since its
introduction as a popular sweetener in the United States has led to much concern regarding
its contribution to the rise in obesity (1), diabetes (2) and related cardiometabolic
disorders (3).Unlike sucrose ... | Other | 4other_research_funding |
gen_55dbbd69a9b59b4d1fe600969027b3f7 | Cross-over Study to Prove Bioequivalence Between Two Brands of Cefalexin Suspension | Corporación Bonima S.A. de C.V. | Bayer | NCT01073540 |
A single dose, two treatments (two cephalexin suspension brands), two sequences, cross-over
design was used with a washout of 7 days between the two study periods. Treatment groups
balanced with the same number of healthy volunteers who were randomly (in two strata: male
and female) assigned to... | Drug | 4other_research_funding |
gen_cc333bbbf8bdf9e9e417fdc90a3453e8 | A Trial of Levodopa in Angelman Syndrome | Children's Hospital Medical Center, Cincinnati | Baylor College of Medicine | NCT01281475 |
This study is designed to determine whether levodopa will lead to an improvement in the
development and tremor in children with Angelman syndrome (AS).
It has been suggested that levodopa, a medication that is usually used to treat Parkinson
disease in adults, may help children with AS in thei... | Drug | 4other_research_funding |
gen_a2adca541895672ba44e65f98f150799 | Study of Tenecteplase (TNK) in Acute Ischemic Stroke (TNK-S2B) | National Institute of Neurological Disorders and Stroke (NINDS) | Clinical Coordinating Center, Department of Neurology, University of Virginia Health System | NCT00252239 |
The purpose of this study is to determine which of 3 different doses of tenecteplase (TNK) is
better for treating stroke patients and if TNK offers an advantage over currently available
treatment with tissue plasminogen activator (tPA).
| Drug | 4other_research_funding |
gen_b31a9a8536000be938483f8fdb1b16ed | GnRH-a for Ovarian Protection During CYC Therapy for Rheumatic Diseases | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | Professor of Internal Medicine | NCT01257802 |
The purpose of this study it to determine whether the use of a gonadotropin releasing hormone
(GnRH)-agonist (depot-leuprolide acetate) during cyclophosphamide (CYC) therapy in women with
rheumatic diseases will provide greater ovarian protection than placebo.
| Drug | 4other_research_funding |
gen_09a3b7e071f160592d0bcdaa0110c79e | ICU Family Communication Study | National Institute of Nursing Research (NINR) | University of Washington, Division of Pulmonary and Critical Care Medicine | NCT00720200 |
The purpose of this study is to improve care in the Intensive Care Unit (ICU) by focusing on
communication with family members of patients who are too sick to make decisions about their
own care while they are in the ICU. The randomized trial will test the efficacy of a
communication interventi... | Behavioral | 4other_research_funding |
gen_8f989005cf92cf14e1cc959840b9ae28 | The Pharmacokinetics of Double Boosted Protease Inhibitors in Antiretroviral-naive HIV-1 Infected Patients | International Antiviral Therapy Evaluation Center | The HIV Netherlands Australia Thailand Research Collaboration | NCT00400738 |
Treatment with only protease inhibitors might benefit HIV patients. Laboratory data have
shown that the combination of saquinavir with lopinavir and ritonavir may a good regimen.
This study will explore this idea.
| Drug | 4other_research_funding |
gen_4c438a7884fbebe5f47c3980d3ab9843 | Structured Treatment of Osteoarthritis of the Knee With or Without Total Knee Replacement | Medical Specialist Heinrich Kopp's Grant | Center for Sensory-Motor Interaction (SMI), Department of Health Sciences and Technology, Aalborg University | NCT01410409 |
The purpose of this study is to test whether surgical insertion of total knee replacement
provides further improvement in quality of life, pain and function in addition to an
algorithm for systematic non-surgical treatment consisting of corrective insoles,
neuromuscular training, weight loss, p... | Behavioral | 4other_research_funding |
gen_0dc1ea055df9878bba4d9721b3a313bd | Resource Sparing Curative Radiotherapy for Locally Advanced Squamous Cell Cancer of the Head and Neck: The HYPNO Trial | Institute Rotary Cancer Hospital, New Delhi, India | University of Maryland | NCT02765503 |
The aim of the study is to test whether a resource-sparing 4-week, 20-fraction course of
accelerated hypofractionated radiotherapy is non-inferior to accelerated radiotherapy
delivering 33 fractions over 5.5 weeks in the treatment of patients with Stage I-IV squamous
cell carcinoma of the phary... | Radiation | 4other_research_funding |
gen_633f6167a208d03fe53c892b9c6cb00c | Blood Pressure in Dialysis Patients | The Cleveland Clinic | Medical University of South Carolina | NCT01421771 |
Hypertension is a major cause of cardiovascular (CV) morbidity and mortality. Although
studies in the general population have demonstrated a continuous reduction in CV risk with
each mmHg drop in systolic blood pressure (SBP), multiple observational studies conducted in
hemodialysis (HD) patien... | Other | 4other_research_funding |
gen_d1c83c273f2f4d1f262599a316e4d81e | Thrombolysis or Anticoagulation for Cerebral Venous Thrombosis | Dutch Heart Foundation | Hôpital Lariboisière, Paris, France | NCT01204333 |
Background: Endovascular thrombolysis, with or without mechanical clot removal (ET), may be
beneficial for a subgroup of patients with cerebral venous sinus thrombosis (CVT), who have a
poor prognosis despite treatment with heparin. Published experience with ET is promising, but
only based on c... | Drug | 4other_research_funding |
gen_bad7e18d965da4f11ba582c046067a89 | Active Bathing to Eliminate Infection (ABATE Infection) Trial | John H. Stroger Hospital | University of Massachusetts, Amherst | NCT02063867 |
The ABATE Infection Project is a cluster randomized trial of hospitals to compare two quality
improvement strategies to reduce multi-drug resistant organisms and healthcare-associated
infections in non-critical care units. The two strategies to be evaluated are:
- Arm 1: Routine Care Routin... | Drug | 4other_research_funding |
gen_856b47edc46414f43f9364df304f7c88 | Diabetes Prevention Program Outcomes Study | Office of Research on Women's Health (ORWH) | University of Tennessee Health Science Center | NCT00038727 |
The Diabetes Prevention Program (DPP) was a multi-center trial examining the ability of an
intensive lifestyle or metformin to prevent or delay the development of diabetes in a high
risk population due to the presence of impaired glucose tolerance (IGT). The DPP has ended
early demonstrating th... | Behavioral | 4other_research_funding |
gen_cbac9f7fc3ff241507dd37c88c769543 | Prevention of Atrial Fibrillation by Inhibition Conversion Enzyme (ICE) After Radiofrequency Ablation of Atrial Flutter | Ministry of Health, France | CHU de Saint-Etienne | NCT00736294 |
Atrial Flutter [AFL] is a relatively frequent arrhythmia, considered as benign, but
associated with both invalidating symptoms and thromboembolic risk. The objective of the
treatment consists to on the one hand the sinus rhythm [SR] restoration and on the other hand
the prevention of the long-t... | Drug | 4other_research_funding |
gen_e00d3b72229a7d63a3ce993623c2999e | Comprehensive Electronic Cancer Support System for the Treatment of Cancer Related Symptoms | National Cancer Institute (NCI) | University of Pittsburgh | NCT01640522 |
The purpose of this study is to test the efficacy of a collaborative care intervention to
manage cancer-related symptoms and improve health related quality of life in patients
diagnosed with hepatobiliary carcinoma.
| Other | 4other_research_funding |
gen_63b87be94045b46913aa882a401e01be | Chemotherapy in Treating Patients With Myelodysplastic Syndrome Before Donor Stem Cell Transplant | National Cancer Institute (NCI) | Fred Hutch/University of Washington Cancer Consortium | NCT01812252 |
This randomized clinical trial studies different chemotherapies in treating patients with
myelodysplastic syndrome before donor stem cell transplant. Giving chemotherapy before a
donor stem cell transplant helps stop the growth of cancer cells in the bone marrow,
including normal blood-forming ... | Drug | 4other_research_funding |
gen_9178191a56aebf671b77f8dd01ea832b | The Respiratory Protection Effectiveness Clinical Trial | Washington D.C. Veterans Affairs Medical Center | Johns Hopkins University School of Medicine/Johns Hopkins Hospital | NCT01249625 |
Despite widespread use of respiratory protective equipment in the U.S. healthcare workplace,
there is very little clinical evidence that respirators prevent healthcare personnel (HCP)
from airborne infectious diseases. Scientific investigation of this issue has been quite
complicated, primarily... | Device | 4other_research_funding |
gen_3d4a2a1fb1223ab06da98ab3901ec5fa | 2-Site Safety Study of Besivance Versus Vigamox Prophylactically in Routine Cataract Surgery | Bausch & Lomb Incorporated | Ophthalmology Associates | NCT01455233 |
The purpose of this study is to demonstrate that Besivance is equal to Vigamox in safety and
tolerance when used prophylactically in subjects undergoing routine cataract surgery.
| Drug | 4other_research_funding |
gen_63de1bb75dae82bdb08bc6fe89cb3982 | Remote Monitoring of Patients With CHF in Central Greece | Institute of Biomedical Research & Technology, Larissa, Greece | Cardiology Department - Regional University Hospital of Larisa | NCT01503463 |
The purpose of this study is to evaluate whether telemonitoring of patients with chronic
heart failure produces a reduction in the combined end point of all cause mortality and
number of hospitalisations, and whether it improves health related quality of life. In
addition, the trials evaluate t... | Procedure | 4other_research_funding |
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