instruction stringlengths 809 2k | output stringlengths 554 1.38k |
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SUBJECT: Patient experiencing side effects on Atorvastatin - medical information and adverse event documentation
BODY:
Dear Medical Information and Commercial Team,
I am a emergency physician writing on behalf of a 58 year old female patient who has been on Atorvastatin. The therapy was initiated 2 weeks ago at a dose ... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "95%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Atorvastatin, a non-company product, evidenced by severe proximal muscle pain, dark cola-colored urine, and profound weak... |
SUBJECT: Medical information request and adverse event report for Metformin
BODY:
Dear Healthcare Information and Quality Assurance Team,
I am a hospitalist writing on behalf of a 62 year old male patient who has been on Metformin. Treatment was started approximately 10 days ago with 100 mg per day.
In the 1 week lead... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "95%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Metformin, a non-company product, evidenced by megaloblastic anemia with hemoglobin dropping to 9.2 g/dL, accompanied by ... |
SUBJECT: Urgent: adverse reaction to Lisinopril with concurrent clinical question
BODY:
Dear Clinical Affairs and Business Development Team,
I am a consultant writing on behalf of a 80 year old male patient who has been on Lisinopril. Treatment was started approximately 14 days ago with 100 mg per day.
Approximately 1... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "97%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Lisinopril, a non-company product, evidenced by creatinine rising from 1.1 mg/dL to 4.2 mg/dL within 5 days of initiation... |
SUBJECT: Adverse reaction to Amoxicillin - clinical guidance and medical information request
BODY:
Dear Scientific Information and Supply Chain Teams,
I am a pathologist writing on behalf of a 54 year old female patient who has been on Amoxicillin. The prescribed regimen is 20 mg and the patient commenced therapy 14 da... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "98%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Amoxicillin, a non-company product, evidenced by fatigue, oral ulcers, and recurrent infections with WBC 2.1 x10^9/L, hem... |
SUBJECT: Safety report and clinical guidance needed for Amlodipine adverse reaction
BODY:
Dear Medical Information and Product Integrity Team,
I am a pathologist writing on behalf of a 29 year old female patient who has been on Amlodipine. Treatment was started approximately 5 weeks ago with 12.5 mg per day.
During th... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "94%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Amlodipine, a non-company product, evidenced by severe sunburn-like reaction after brief outdoor exposure, with erythema,... |
SUBJECT: Urgent: adverse reaction to Amoxicillin with concurrent clinical question
BODY:
Dear Scientific Information and Supply Chain Teams,
I am a surgeon writing on behalf of a 67 year old male patient who has been on Amoxicillin. The therapy was initiated 3 weeks ago at a dose of 100 mg.
In the 5 days leading up to... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "97%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Amoxicillin, a non-company product, evidenced by generalized tonic-clonic seizures occurring on day 4 of therapy in a pat... |
SUBJECT: Patient safety concern and information request - Amoxicillin related
BODY:
Dear Medical Information and Safety Team,
I am writing as the husband of a 71 year old female patient who is taking Amoxicillin. Treatment was started approximately 9 weeks ago with 5 mg per day.
Over the past 8 days, she developed fat... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "93%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Amoxicillin, a non-company product, evidenced by fatigue, oral ulcers, and recurrent infections with WBC 2.1 x10^9/L, hem... |
SUBJECT: Patient safety concern and information request - Ibuprofen related
BODY:
Dear Healthcare Information and Quality Assurance Team,
I am writing as the wife of a 50 year old female patient who is taking Ibuprofen. The prescribed regimen is 5 mg and she commenced therapy 7 weeks ago.
During the past 3 weeks, she ... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "97%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Ibuprofen, a non-company product, evidenced by creatinine rising from 0.9 mg/dL to 3.4 mg/dL over 10 days of high-dose us... |
SUBJECT: Side effects from Amlodipine and a dosing question
BODY:
Dear Medical Information and Safety Team,
I am a anaesthesiologist writing on behalf of a 29 year old male patient who has been on Amlodipine. the patient has been on this medication for 12 weeks at 40 mg daily.
Over the past 2 weeks, the patient develo... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "95%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Amlodipine, a non-company product, evidenced by severe gingival overgrowth covering 60% of tooth surfaces causing bleedin... |
SUBJECT: Side effects from Amlodipine and a dosing question
BODY:
Dear Medical Affairs and Quality Department,
I am a pulmonologist writing on behalf of a 70 year old female patient who has been on Amlodipine. The prescribed regimen is 150 mcg and the patient commenced therapy 9 weeks ago.
In the 4 days leading up to ... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "93%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Amlodipine, a non-company product, evidenced by palpitations with resting heart rate of 110 bpm, chest discomfort, anxiet... |
SUBJECT: Patient experiencing toxicity concerns on Levothyroxine - medical information and adverse event documentation
BODY:
Dear Medical Affairs and Quality Department,
I am a plastic surgeon writing on behalf of a 71 year old female patient who has been on Levothyroxine. The prescribed regimen is 80 mg and the patien... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "94%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Levothyroxine, a non-company product, evidenced by agitation, paranoid delusions, visual hallucinations, and pressured sp... |
SUBJECT: Urgent: adverse reaction to Amoxicillin with concurrent clinical question
BODY:
Dear Medical Information and Product Integrity Team,
I am a endocrinologist writing on behalf of a 76 year old male patient who has been on Amoxicillin. The prescribed regimen is 80 mg and the patient commenced therapy 10 days ago.... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "98%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Amoxicillin, a non-company product, evidenced by generalized tonic-clonic seizures occurring on day 4 of therapy in a pat... |
SUBJECT: Methotrexate related adverse event report and clinical inquiry
BODY:
Dear Medical Affairs and Quality Department,
I am a psychiatrist writing on behalf of a 16 year old male patient who has been on Methotrexate. The therapy was initiated 2 weeks ago at a dose of 250 mg.
During the past 9 days, the patient pre... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "97%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Methotrexate, a non-company product, evidenced by fever, oral ulcers, and sepsis with CBC showing WBC 1.8 x10^9/L, hemogl... |
SUBJECT: Urgent: adverse reaction to Metformin with concurrent clinical question
BODY:
Dear Medical Information and Product Integrity Team,
I am a surgeon writing on behalf of a 83 year old female patient who has been on Metformin. the patient has been on this medication for 3 months at 15 mg daily.
Approximately 9 da... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "96%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Metformin, a non-company product, evidenced by complete loss of appetite, early satiety, and unintended weight loss of 8 ... |
SUBJECT: Urgent: adverse reaction to Atorvastatin with concurrent clinical question
BODY:
Dear Clinical and Product Safety Teams,
I am a intensivist writing on behalf of a 85 year old male patient who has been on Atorvastatin. The prescribed regimen is 40 mg and the patient commenced therapy 21 days ago.
Approximately... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "94%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Atorvastatin, a non-company product, evidenced by jaundice with bilirubin 3.2 mg/dL, ALT 340 U/L, and alkaline phosphatas... |
SUBJECT: Adverse event documentation and dosing guidance for Omeprazole
BODY:
Dear Medical Affairs and Pharmacovigilance Team,
I am writing as the husband of a 55 year old female patient who is taking Omeprazole. The therapy was initiated 3 months ago at a dose of 80 mg.
In the 2 weeks leading up to this report, she s... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "94%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Omeprazole, a non-company product, evidenced by right femoral neck fracture after a minor fall from standing height with ... |
SUBJECT: Adverse reaction to Omeprazole - clinical guidance and medical information request
BODY:
Dear Scientific Information and Supply Chain Teams,
I am a dr. writing on behalf of a 62 year old male patient who has been on Omeprazole. the patient has been on this medication for 21 days at 500 mg daily.
During the pa... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "95%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Omeprazole, a non-company product, evidenced by severe muscle spasms, carpopedal tetany, and ventricular arrhythmia with ... |
SUBJECT: Clinical query and adverse event notification - Ibuprofen therapy
BODY:
Dear Medical Information and Safety Team,
I am a cardiologist writing on behalf of a 16 year old male patient who has been on Ibuprofen. the patient has been on this medication for 14 days at 5 mg daily.
In the 4 days leading up to this r... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "96%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Ibuprofen, a non-company product, evidenced by painful mucosal erosions of the oral cavity and conjunctivae, targetoid sk... |
SUBJECT: Clinical query and adverse event notification - Metformin therapy
BODY:
Dear Scientific Information and Supply Chain Teams,
I am a nurse practitioner reporting on behalf of a 75 year old male patient under our care who has been prescribed Metformin. Treatment was started approximately 3 months ago with 10 mg p... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "95%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Metformin, a non-company product, evidenced by platelet count dropped to 68 x10^9/L with petechial rash and epistaxis dev... |
SUBJECT: Safety report and clinical guidance needed for Metformin adverse reaction
BODY:
Dear Medical Information and Regulatory Affairs Team,
I am a gp writing on behalf of a 37 year old female patient who has been on Metformin. The therapy was initiated 8 weeks ago at a dose of 15 mg.
During the past 12 days, the pa... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "97%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Metformin, a non-company product, evidenced by persistent vomiting up to 8 times daily, watery diarrhea, and abdominal bl... |
SUBJECT: Urgent: adverse reaction to Methotrexate with concurrent clinical question
BODY:
Dear Medical Information and Product Integrity Team,
I am a physician assistant writing on behalf of a 50 year old male patient who has been on Methotrexate. Treatment was started approximately 5 weeks ago with 25 mg per day.
App... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "98%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Methotrexate, a non-company product, evidenced by severe oral ulcerations extending to the esophagus, preventing oral int... |
SUBJECT: Medical information request and adverse event report for Amoxicillin
BODY:
Dear Clinical Affairs and Business Development Team,
I am a nurse practitioner reporting on behalf of a 49 year old male patient under our care who has been prescribed Amoxicillin. The prescribed regimen is 12.5 mg and the patient comme... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "97%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Amoxicillin, a non-company product, evidenced by pruritus, jaundice, dark urine, and pale stools with bilirubin 5.8 mg/dL... |
SUBJECT: Adverse event documentation and dosing guidance for Lisinopril
BODY:
Dear Medical Information and Product Integrity Team,
I am writing as the daughter of a 45 year old male patient who is taking Lisinopril. he has been on this medication for 5 months at 30 mg daily.
In the 12 days leading up to this report, h... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "93%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Lisinopril, a non-company product, evidenced by persistent dry nonproductive cough occurring day and night, disturbing sl... |
SUBJECT: Levothyroxine related adverse event report and clinical inquiry
BODY:
Dear Clinical Affairs and Business Development Team,
I am a 29 year old male patient and I have been prescribed Levothyroxine. Treatment was started approximately 21 days ago with 100 mg per day.
In the 8 days leading up to this report, he ... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "95%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Levothyroxine, a non-company product, evidenced by crushing substernal chest pain, ST elevation in anterior leads V1 thro... |
SUBJECT: Medical information request and adverse event report for Ibuprofen
BODY:
Dear Medical Information and Regulatory Affairs Team,
I am a plastic surgeon writing on behalf of a 58 year old female patient who has been on Ibuprofen. The therapy was initiated 3 months ago at a dose of 80 mg.
During the past 10 days,... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "93%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Ibuprofen, a non-company product, evidenced by severe headache, neck stiffness, photophobia, and fever with normal CSF ba... |
SUBJECT: Safety report and clinical guidance needed for Levothyroxine adverse reaction
BODY:
Dear Medical Information and Product Integrity Team,
I am a gastroenterologist writing on behalf of a 75 year old female patient who has been on Levothyroxine. The prescribed regimen is 12.5 mg and the patient commenced therapy... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "98%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Levothyroxine, a non-company product, evidenced by chronic loose stools, steatorrhea, and weight loss of 6 kg with low fe... |
SUBJECT: Adverse event documentation and dosing guidance for Methotrexate
BODY:
Dear Clinical and Product Safety Teams,
I am a nurse reporting on behalf of a 76 year old female patient under our care who has been prescribed Methotrexate. The therapy was initiated 3 weeks ago at a dose of 125 mcg.
Over the past 12 days... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "94%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Methotrexate, a non-company product, evidenced by severe oral ulcerations extending to the esophagus, preventing oral int... |
SUBJECT: Side effects from Metformin and a dosing question
BODY:
Dear Clinical Affairs and Business Development Team,
I am a hospitalist writing on behalf of a 65 year old female patient who has been on Metformin. The therapy was initiated 4 months ago at a dose of 150 mcg.
Over the past 6 days, the patient developed ... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "93%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Metformin, a non-company product, evidenced by profound weakness, nausea, abdominal discomfort, and Kussmaul respirations... |
SUBJECT: Urgent: adverse reaction to Ibuprofen with concurrent clinical question
BODY:
Dear Scientific Information and Supply Chain Teams,
I am a 50 year old male patient and I have been prescribed Ibuprofen. he has been on this medication for 12 weeks at 2.5 mg daily.
Over the past 14 days, he developed painful mucos... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "93%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Ibuprofen, a non-company product, evidenced by painful mucosal erosions of the oral cavity and conjunctivae, targetoid sk... |
SUBJECT: Safety report and clinical guidance needed for Omeprazole adverse reaction
BODY:
Dear Medical Information and Safety Team,
I am writing as the husband of a 62 year old female patient who is taking Omeprazole. Treatment was started approximately 14 days ago with 30 mg per day.
In the 6 days leading up to this ... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "93%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Omeprazole, a non-company product, evidenced by macrocytic anemia with MCV 108 fL, hemoglobin 9.6 g/dL, and serum B12 of ... |
SUBJECT: Safety report and clinical guidance needed for Levothyroxine adverse reaction
BODY:
Dear Medical Information and Regulatory Affairs Team,
I am a cardiologist writing on behalf of a 41 year old male patient who has been on Levothyroxine. The prescribed regimen is 250 mg and the patient commenced therapy 5 weeks... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "95%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Levothyroxine, a non-company product, evidenced by severe exercise limitation, dyspnea on mild exertion, and resting tach... |
SUBJECT: Adverse event documentation and dosing guidance for Amlodipine
BODY:
Dear Medical Information and Commercial Team,
I am a hospitalist writing on behalf of a 32 year old female patient who has been on Amlodipine. Treatment was started approximately 14 days ago with 15 mg per day.
Approximately 5 days ago, the ... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "93%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Amlodipine, a non-company product, evidenced by palpitations with resting heart rate of 110 bpm, chest discomfort, anxiet... |
SUBJECT: Adverse event documentation and dosing guidance for Methotrexate
BODY:
Dear Medical Information and Safety Team,
I am a pathologist writing on behalf of a 65 year old male patient who has been on Methotrexate. The therapy was initiated 5 weeks ago at a dose of 2000 mg.
During the past 5 days, the patient pres... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "95%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Methotrexate, a non-company product, evidenced by severe oral ulcerations extending to the esophagus, preventing oral int... |
SUBJECT: Patient experiencing therapy-related adverse event on Amlodipine - medical information and adverse event documentation
BODY:
Dear Medical Affairs and Quality Department,
I am a intensivist writing on behalf of a 55 year old female patient who has been on Amlodipine. the patient has been on this medication for ... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "95%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Amlodipine, a non-company product, evidenced by new-onset low mood, anhedonia, psychomotor retardation, and early morning... |
SUBJECT: Urgent: adverse reaction to Methotrexate with concurrent clinical question
BODY:
Dear Medical Information and Safety Team,
I am writing as the wife of a 49 year old male patient who is taking Methotrexate. The therapy was initiated 5 weeks ago at a dose of 7.5 mg.
Approximately 6 days ago, he began experienci... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "97%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Methotrexate, a non-company product, evidenced by new cervical lymphadenopathy, B symptoms with night sweats and 4 kg wei... |
SUBJECT: Adverse event documentation and dosing guidance for Omeprazole
BODY:
Dear Medical Affairs and Quality Department,
I am a hematologist writing on behalf of a 80 year old female patient who has been on Omeprazole. The therapy was initiated 1 month ago at a dose of 50 mg.
During the past 10 days, the patient pre... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "97%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Omeprazole, a non-company product, evidenced by rapid cognitive decline over 18 months with MMSE falling from 28 to 19, e... |
SUBJECT: Safety report and clinical guidance needed for Levothyroxine adverse reaction
BODY:
Dear Medical Affairs and Quality Department,
I am a anaesthesiologist writing on behalf of a 41 year old female patient who has been on Levothyroxine. the patient has been on this medication for 12 weeks at 30 mg daily.
During... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "94%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Levothyroxine, a non-company product, evidenced by crushing substernal chest pain, ST elevation in anterior leads V1 thro... |
SUBJECT: Side effects from Methotrexate and a dosing question
BODY:
Dear Medical Information and Commercial Team,
I am a charge nurse reporting on behalf of a 45 year old male patient under our care who has been prescribed Methotrexate. Treatment was started approximately 4 months ago with 25 mg per day.
During the pa... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "98%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Methotrexate, a non-company product, evidenced by jaundice, fatigue, pruritus, and hepatomegaly with liver biopsy showing... |
SUBJECT: Urgent: adverse reaction to Amoxicillin with concurrent clinical question
BODY:
Dear Medical Information and Product Integrity Team,
I am a radiologist writing on behalf of a 16 year old female patient who has been on Amoxicillin. Treatment was started approximately 5 months ago with 100 mg per day.
In the 6 ... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "96%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Amoxicillin, a non-company product, evidenced by rapidly progressive erythema, blistering, and full-thickness epidermal d... |
SUBJECT: Patient safety concern and information request - Lisinopril related
BODY:
Dear Clinical Affairs and Business Development Team,
I am a clinical pharmacist and I am contacting you regarding a 44 year old male patient for whom Lisinopril was dispensed from our pharmacy. Treatment was started approximately 9 weeks... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "96%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Lisinopril, a non-company product, evidenced by severe epigastric pain radiating to the back, serum lipase 1200 U/L, and ... |
SUBJECT: Adverse event documentation and dosing guidance for Lisinopril
BODY:
Dear Medical Affairs and Quality Department,
I am a 49 year old female patient and I have been prescribed Lisinopril. Treatment was started approximately 14 days ago with 7.5 mg per day.
Approximately 5 days ago, she began experiencing fever... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "98%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Lisinopril, a non-company product, evidenced by fever, sore throat, and severe neutropenia with absolute neutrophil count... |
SUBJECT: Urgent: adverse reaction to Methotrexate with concurrent clinical question
BODY:
Dear Medical Information and Regulatory Affairs Team,
I am a geriatrician writing on behalf of a 25 year old female patient who has been on Methotrexate. the patient has been on this medication for 9 weeks at 20 mg daily.
In the ... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "94%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Methotrexate, a non-company product, evidenced by disseminated histoplasmosis with fever, weight loss, hepatosplenomegaly... |
SUBJECT: Adverse event documentation and dosing guidance for Amoxicillin
BODY:
Dear Medical Affairs and Pharmacovigilance Team,
I am a neurologist writing on behalf of a 75 year old male patient who has been on Amoxicillin. Treatment was started approximately 5 months ago with 100 mg per day.
In the 12 days leading up... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "94%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Amoxicillin, a non-company product, evidenced by rapidly progressive erythema, blistering, and full-thickness epidermal d... |
SUBJECT: Adverse reaction to Levothyroxine - clinical guidance and medical information request
BODY:
Dear Medical Affairs and Pharmacovigilance Team,
I am a clinical pharmacist and I am contacting you regarding a 65 year old female patient for whom Levothyroxine was dispensed from our pharmacy. Treatment was started ap... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "95%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Levothyroxine, a non-company product, evidenced by crushing substernal chest pain, ST elevation in anterior leads V1 thro... |
SUBJECT: Medical information request and adverse event report for Lisinopril
BODY:
Dear Clinical Affairs and Business Development Team,
I am a pulmonologist writing on behalf of a 44 year old female patient who has been on Lisinopril. The prescribed regimen is 150 mcg and the patient commenced therapy 3 months ago.
Du... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "97%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Lisinopril, a non-company product, evidenced by flushing, urticaria, abdominal cramping, and hypotension of 76/44 mmHg wi... |
SUBJECT: Medical information request and adverse event report for Lisinopril
BODY:
Dear Healthcare Information and Quality Assurance Team,
I am a cardiologist writing on behalf of a 41 year old male patient who has been on Lisinopril. The prescribed regimen is 2000 mg and the patient commenced therapy 1 month ago.
Ove... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "98%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Lisinopril, a non-company product, evidenced by persistent dry nonproductive cough occurring day and night, disturbing sl... |
SUBJECT: Amlodipine related adverse event report and clinical inquiry
BODY:
Dear Medical Affairs and Pharmacovigilance Team,
I am writing as the son of a 41 year old male patient who is taking Amlodipine. The therapy was initiated 9 weeks ago at a dose of 100 mg.
Approximately 1 week ago, he began experiencing new-ons... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "96%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Amlodipine, a non-company product, evidenced by new-onset low mood, anhedonia, psychomotor retardation, and early morning... |
SUBJECT: Patient experiencing hypersensitivity reaction on Amoxicillin - medical information and adverse event documentation
BODY:
Dear Clinical Affairs and Business Development Team,
I am a endocrinologist writing on behalf of a 28 year old male patient who has been on Amoxicillin. the patient has been on this medicat... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "96%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Amoxicillin, a non-company product, evidenced by fatigue, pallor, dark urine, and jaundice with hemoglobin dropping to 7.... |
SUBJECT: Clinical query and adverse event notification - Omeprazole therapy
BODY:
Dear Clinical Affairs and Business Development Team,
I am a orthopedic surgeon writing on behalf of a 55 year old female patient who has been on Omeprazole. The therapy was initiated 5 months ago at a dose of 25 mg.
In the 3 weeks leadin... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "93%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Omeprazole, a non-company product, evidenced by fever of 39.4 C, productive cough, right lower lobe consolidation on ches... |
SUBJECT: Medical information request and adverse event report for Levothyroxine
BODY:
Dear Medical Information and Commercial Team,
I am a geriatrician writing on behalf of a 75 year old female patient who has been on Levothyroxine. the patient has been on this medication for 9 weeks at 40 mg daily.
Approximately 14 d... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "96%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Levothyroxine, a non-company product, evidenced by compression fracture of L2 vertebra after minor lifting with T-score -... |
SUBJECT: Patient safety concern and information request - Metformin related
BODY:
Dear Medical Information and Regulatory Affairs Team,
I am writing as the brother of a 28 year old male patient who is taking Metformin. Treatment was started approximately 6 weeks ago with 7.5 mg per day.
Approximately 10 days ago, he b... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "96%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Metformin, a non-company product, evidenced by complete loss of appetite, early satiety, and unintended weight loss of 8 ... |
SUBJECT: Side effects from Atorvastatin and a dosing question
BODY:
Dear Clinical Affairs and Business Development Team,
I am writing as the son of a 70 year old female patient who is taking Atorvastatin. Treatment was started approximately 2 weeks ago with 80 mg per day.
Approximately 9 days ago, she began experienci... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "96%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Atorvastatin, a non-company product, evidenced by fasting glucose rising from 98 mg/dL to 142 mg/dL after 8 months of the... |
SUBJECT: Side effects from Metformin and a dosing question
BODY:
Dear Clinical and Product Safety Teams,
I am a specialist writing on behalf of a 25 year old female patient who has been on Metformin. The therapy was initiated 21 days ago at a dose of 25 mg.
Approximately 1 week ago, the patient began experiencing comp... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "97%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Metformin, a non-company product, evidenced by complete loss of appetite, early satiety, and unintended weight loss of 8 ... |
SUBJECT: Adverse event documentation and dosing guidance for Amoxicillin
BODY:
Dear Healthcare Information and Quality Assurance Team,
I am a urologist writing on behalf of a 44 year old male patient who has been on Amoxicillin. The prescribed regimen is 150 mcg and the patient commenced therapy 21 days ago.
Over the ... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "94%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Amoxicillin, a non-company product, evidenced by generalized tonic-clonic seizures occurring on day 4 of therapy in a pat... |
SUBJECT: Side effects from Lisinopril and a dosing question
BODY:
Dear Medical Information and Commercial Team,
I am a physician writing on behalf of a 76 year old female patient who has been on Lisinopril. The therapy was initiated 3 months ago at a dose of 100 mg.
Approximately 1 week ago, the patient began experien... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "93%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Lisinopril, a non-company product, evidenced by persistent dry nonproductive cough occurring day and night, disturbing sl... |
SUBJECT: Patient safety concern and information request - Methotrexate related
BODY:
Dear Medical Affairs and Pharmacovigilance Team,
I am a cardiologist writing on behalf of a 70 year old male patient who has been on Methotrexate. the patient has been on this medication for 4 months at 500 mg daily.
Over the past 2 w... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "97%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Methotrexate, a non-company product, evidenced by severe oral ulcerations extending to the esophagus, preventing oral int... |
SUBJECT: Patient safety concern and information request - Lisinopril related
BODY:
Dear Healthcare Information and Quality Assurance Team,
I am a surgeon writing on behalf of a 62 year old male patient who has been on Lisinopril. The therapy was initiated 5 months ago at a dose of 1000 mg.
During the past 8 days, the ... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "98%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Lisinopril, a non-company product, evidenced by sudden swelling of the tongue, lips, and larynx causing airway compromise... |
SUBJECT: Safety report and clinical guidance needed for Metformin adverse reaction
BODY:
Dear Clinical and Product Safety Teams,
I am a 55 year old female patient and I have been prescribed Metformin. The therapy was initiated 1 month ago at a dose of 50 mg.
Approximately 10 days ago, she began experiencing rapid brea... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "95%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Metformin, a non-company product, evidenced by rapid breathing, severe abdominal pain, muscle cramps, and extreme fatigue... |
SUBJECT: Clinical query and adverse event notification - Amlodipine therapy
BODY:
Dear Scientific Information and Supply Chain Teams,
I am a pathologist writing on behalf of a 60 year old male patient who has been on Amlodipine. The prescribed regimen is 1000 mg and the patient commenced therapy 10 days ago.
In the 12... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "98%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Amlodipine, a non-company product, evidenced by new-onset low mood, anhedonia, psychomotor retardation, and early morning... |
SUBJECT: Medical information request and adverse event report for Omeprazole
BODY:
Dear Clinical and Product Safety Teams,
I am a 75 year old male patient and I have been prescribed Omeprazole. The therapy was initiated 1 month ago at a dose of 150 mcg.
Approximately 14 days ago, he began experiencing endoscopic surve... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "98%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Omeprazole, a non-company product, evidenced by endoscopic surveillance revealing numerous sessile polyps in the gastric ... |
SUBJECT: Patient safety concern and information request - Metformin related
BODY:
Dear Scientific Information and Supply Chain Teams,
I am a gastroenterologist writing on behalf of a 71 year old female patient who has been on Metformin. The therapy was initiated 3 months ago at a dose of 100 mg.
During the past 5 days... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "98%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Metformin, a non-company product, evidenced by profound weakness, nausea, abdominal discomfort, and Kussmaul respirations... |
SUBJECT: Adverse reaction to Methotrexate - clinical guidance and medical information request
BODY:
Dear Clinical and Product Safety Teams,
I am writing as the mother of a 55 year old female patient who is taking Methotrexate. she has been on this medication for 21 days at 15 mg daily.
In the 14 days leading up to thi... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "98%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Methotrexate, a non-company product, evidenced by fever, oral ulcers, and sepsis with CBC showing WBC 1.8 x10^9/L, hemogl... |
SUBJECT: Side effects from Methotrexate and a dosing question
BODY:
Dear Medical Information and Safety Team,
I am a family medicine physician writing on behalf of a 49 year old female patient who has been on Methotrexate. the patient has been on this medication for 9 weeks at 12.5 mg daily.
Over the past 10 days, the... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "96%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Methotrexate, a non-company product, evidenced by severe oral ulcerations extending to the esophagus, preventing oral int... |
SUBJECT: Patient safety concern and information request - Amlodipine related
BODY:
Dear Medical Affairs and Pharmacovigilance Team,
I am a intensivist writing on behalf of a 41 year old male patient who has been on Amlodipine. The therapy was initiated 4 months ago at a dose of 12.5 mg.
In the 3 weeks leading up to th... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "94%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Amlodipine, a non-company product, evidenced by severe sunburn-like reaction after brief outdoor exposure, with erythema,... |
SUBJECT: Patient safety concern and information request - Amoxicillin related
BODY:
Dear Medical Information and Regulatory Affairs Team,
I am a orthopedic surgeon writing on behalf of a 28 year old male patient who has been on Amoxicillin. Treatment was started approximately 10 days ago with 7.5 mg per day.
In the 2 ... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "93%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Amoxicillin, a non-company product, evidenced by rapidly progressive erythema, blistering, and full-thickness epidermal d... |
SUBJECT: Adverse event documentation and dosing guidance for Lisinopril
BODY:
Dear Scientific Information and Supply Chain Teams,
I am a 76 year old male patient and I have been prescribed Lisinopril. The therapy was initiated 8 weeks ago at a dose of 5 mg.
Over the past 12 days, he developed jaundice, dark urine, ele... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "97%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Lisinopril, a non-company product, evidenced by jaundice, dark urine, elevated ALT to 480 U/L and AST to 390 U/L with pos... |
SUBJECT: Medical information request and adverse event report for Atorvastatin
BODY:
Dear Scientific Information and Supply Chain Teams,
I am writing as the son of a 61 year old male patient who is taking Atorvastatin. he has been on this medication for 7 weeks at 250 mg daily.
Over the past 3 weeks, he developed prog... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "97%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Atorvastatin, a non-company product, evidenced by progressive severe proximal muscle weakness with CK persistently above ... |
SUBJECT: Adverse event documentation and dosing guidance for Amoxicillin
BODY:
Dear Medical Affairs and Quality Department,
I am writing as the caregiver of a 50 year old female patient who is taking Amoxicillin. The prescribed regimen is 15 mg and she commenced therapy 14 days ago.
Approximately 8 days ago, she began... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "97%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Amoxicillin, a non-company product, evidenced by widespread pruritic maculopapular rash involving 80% of body surface are... |
SUBJECT: Clinical query and adverse event notification - Atorvastatin therapy
BODY:
Dear Clinical Affairs and Business Development Team,
I am a charge nurse reporting on behalf of a 58 year old male patient under our care who has been prescribed Atorvastatin. The therapy was initiated 12 weeks ago at a dose of 30 mg.
... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "94%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Atorvastatin, a non-company product, evidenced by progressive burning sensation and numbness in both feet with reduced vi... |
SUBJECT: Patient safety concern and information request - Metformin related
BODY:
Dear Medical Information and Regulatory Affairs Team,
I am writing as the wife of a 45 year old male patient who is taking Metformin. he has been on this medication for 5 weeks at 1000 mg daily.
Approximately 4 days ago, he began experie... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "98%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Metformin, a non-company product, evidenced by platelet count dropped to 68 x10^9/L with petechial rash and epistaxis dev... |
SUBJECT: Metformin related adverse event report and clinical inquiry
BODY:
Dear Scientific Information and Supply Chain Teams,
I am a charge nurse reporting on behalf of a 67 year old male patient under our care who has been prescribed Metformin. Treatment was started approximately 8 weeks ago with 50 mg per day.
In t... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "97%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Metformin, a non-company product, evidenced by severe epigastric pain radiating to the back, serum lipase 980 U/L, and am... |
SUBJECT: Levothyroxine related adverse event report and clinical inquiry
BODY:
Dear Medical Information and Commercial Team,
I am a 61 year old female patient and I have been prescribed Levothyroxine. Treatment was started approximately 2 weeks ago with 75 mcg per day.
During the past 8 days, she presented with agitat... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "95%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Levothyroxine, a non-company product, evidenced by agitation, paranoid delusions, visual hallucinations, and pressured sp... |
SUBJECT: Safety report and clinical guidance needed for Atorvastatin adverse reaction
BODY:
Dear Clinical and Product Safety Teams,
I am writing as the wife of a 37 year old female patient who is taking Atorvastatin. The prescribed regimen is 5 mg and she commenced therapy 6 weeks ago.
In the 1 week leading up to this... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "95%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Atorvastatin, a non-company product, evidenced by new-onset depressed mood, anhedonia, fatigue, and passive suicidal idea... |
SUBJECT: Patient safety concern and information request - Amlodipine related
BODY:
Dear Medical Information and Regulatory Affairs Team,
I am a family medicine physician writing on behalf of a 50 year old female patient who has been on Amlodipine. The prescribed regimen is 25 mg and the patient commenced therapy 5 mont... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "95%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Amlodipine, a non-company product, evidenced by palpitations with resting heart rate of 110 bpm, chest discomfort, anxiet... |
SUBJECT: Patient experiencing side effects on Methotrexate - medical information and adverse event documentation
BODY:
Dear Clinical Affairs and Business Development Team,
I am writing as the mother of a 33 year old male patient who is taking Methotrexate. Treatment was started approximately 14 days ago with 150 mcg pe... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "94%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Methotrexate, a non-company product, evidenced by jaundice, fatigue, pruritus, and hepatomegaly with liver biopsy showing... |
SUBJECT: Adverse event documentation and dosing guidance for Levothyroxine
BODY:
Dear Clinical and Product Safety Teams,
I am a hospitalist writing on behalf of a 70 year old male patient who has been on Levothyroxine. The prescribed regimen is 20 mg and the patient commenced therapy 6 weeks ago.
Over the past 8 days,... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "94%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Levothyroxine, a non-company product, evidenced by irregularly irregular pulse with heart rate 140 bpm, dyspnea on exerti... |
SUBJECT: Adverse event documentation and dosing guidance for Methotrexate
BODY:
Dear Medical Affairs and Quality Department,
I am a nurse practitioner reporting on behalf of a 62 year old male patient under our care who has been prescribed Methotrexate. The therapy was initiated 3 months ago at a dose of 150 mcg.
Over... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "93%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Methotrexate, a non-company product, evidenced by spontaneous miscarriage at 8 weeks gestation in a patient who conceived... |
SUBJECT: Patient safety concern and information request - Lisinopril related
BODY:
Dear Medical Information and Regulatory Affairs Team,
I am a surgeon writing on behalf of a 19 year old male patient who has been on Lisinopril. The therapy was initiated 7 weeks ago at a dose of 7.5 mg.
In the 12 days leading up to thi... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "98%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Lisinopril, a non-company product, evidenced by creatinine rising from 1.1 mg/dL to 4.2 mg/dL within 5 days of initiation... |
SUBJECT: Patient safety concern and information request - Metformin related
BODY:
Dear Scientific Information and Supply Chain Teams,
I am a anaesthesiologist writing on behalf of a 60 year old female patient who has been on Metformin. the patient has been on this medication for 6 weeks at 20 mg daily.
In the 9 days l... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "98%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Metformin, a non-company product, evidenced by severe epigastric pain radiating to the back, serum lipase 980 U/L, and am... |
SUBJECT: Adverse event documentation and dosing guidance for Amlodipine
BODY:
Dear Medical Affairs and Pharmacovigilance Team,
I am a physician assistant writing on behalf of a 16 year old female patient who has been on Amlodipine. The therapy was initiated 7 weeks ago at a dose of 125 mcg.
During the past 9 days, the... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "95%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Amlodipine, a non-company product, evidenced by bilateral pitting edema extending to the knees, with weight gain of 6 kg ... |
SUBJECT: Side effects from Atorvastatin and a dosing question
BODY:
Dear Medical Information and Product Integrity Team,
I am writing as the wife of a 52 year old female patient who is taking Atorvastatin. The therapy was initiated 8 weeks ago at a dose of 250 mg.
During the past 12 days, she presented with spontaneou... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "95%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Atorvastatin, a non-company product, evidenced by spontaneous rupture of the left Achilles tendon during normal walking w... |
SUBJECT: Clinical query and adverse event notification - Omeprazole therapy
BODY:
Dear Medical Affairs and Pharmacovigilance Team,
I am a 19 year old female patient and I have been prescribed Omeprazole. The therapy was initiated 2 weeks ago at a dose of 75 mcg.
In the 2 weeks leading up to this report, she showed sig... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "94%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Omeprazole, a non-company product, evidenced by photosensitive annular and psoriasiform plaques on the upper back, chest,... |
SUBJECT: Medical information request and adverse event report for Amlodipine
BODY:
Dear Scientific Information and Supply Chain Teams,
I am a family medicine physician writing on behalf of a 76 year old male patient who has been on Amlodipine. The prescribed regimen is 500 mg and the patient commenced therapy 12 weeks ... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "94%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Amlodipine, a non-company product, evidenced by bilateral pitting edema extending to the knees, with weight gain of 6 kg ... |
SUBJECT: Safety report and clinical guidance needed for Atorvastatin adverse reaction
BODY:
Dear Medical Affairs and Pharmacovigilance Team,
I am a general practitioner writing on behalf of a 67 year old female patient who has been on Atorvastatin. The prescribed regimen is 1000 mg and the patient commenced therapy 5 w... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "98%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Atorvastatin, a non-company product, evidenced by severe proximal muscle pain, dark cola-colored urine, and profound weak... |
SUBJECT: Medical information request and adverse event report for Amlodipine
BODY:
Dear Medical Information and Regulatory Affairs Team,
I am writing as the mother of a 85 year old female patient who is taking Amlodipine. she has been on this medication for 14 days at 5 mg daily.
During the past 2 weeks, she presented... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "95%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Amlodipine, a non-company product, evidenced by severe gingival overgrowth covering 60% of tooth surfaces causing bleedin... |
SUBJECT: Clinical query and adverse event notification - Methotrexate therapy
BODY:
Dear Medical Information and Product Integrity Team,
I am writing as the son of a 58 year old female patient who is taking Methotrexate. The therapy was initiated 10 days ago at a dose of 2000 mg.
Approximately 10 days ago, she began e... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "95%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Methotrexate, a non-company product, evidenced by oliguria, rising creatinine from 0.9 to 5.4 mg/dL, and hyperkalemia fol... |
SUBJECT: Amoxicillin related adverse event report and clinical inquiry
BODY:
Dear Medical Affairs and Pharmacovigilance Team,
I am a psychiatrist writing on behalf of a 16 year old male patient who has been on Amoxicillin. the patient has been on this medication for 14 days at 100 mg daily.
Approximately 10 days ago, ... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "93%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Amoxicillin, a non-company product, evidenced by fatigue, oral ulcers, and recurrent infections with WBC 2.1 x10^9/L, hem... |
SUBJECT: Omeprazole related adverse event report and clinical inquiry
BODY:
Dear Healthcare Information and Quality Assurance Team,
I am a emergency physician writing on behalf of a 58 year old male patient who has been on Omeprazole. Treatment was started approximately 12 weeks ago with 12.5 mg per day.
Over the past... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "95%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Omeprazole, a non-company product, evidenced by profuse watery diarrhea 14 times per day, fever of 38.5 C, leukocytosis o... |
SUBJECT: Adverse event documentation and dosing guidance for Ibuprofen
BODY:
Dear Medical Affairs and Quality Department,
I am writing as the mother of a 52 year old male patient who is taking Ibuprofen. The therapy was initiated 9 weeks ago at a dose of 125 mcg.
In the 10 days leading up to this report, he showed sig... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "95%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Ibuprofen, a non-company product, evidenced by blood pressure surge to 198/116 mmHg with headache, chest pain, and papill... |
SUBJECT: Side effects from Amoxicillin and a dosing question
BODY:
Dear Medical Affairs and Pharmacovigilance Team,
I am writing as the sister of a 61 year old male patient who is taking Amoxicillin. The prescribed regimen is 40 mg and he commenced therapy 8 weeks ago.
During the past 3 weeks, he presented with fever,... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "97%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Amoxicillin, a non-company product, evidenced by fever, rash, eosinophilia of 2200 per microliter, and acute kidney injur... |
SUBJECT: Adverse reaction to Levothyroxine - clinical guidance and medical information request
BODY:
Dear Medical Affairs and Quality Department,
I am writing as the wife of a 52 year old female patient who is taking Levothyroxine. The prescribed regimen is 25 mg and she commenced therapy 5 months ago.
In the 6 days l... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "93%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Levothyroxine, a non-company product, evidenced by crushing substernal chest pain, ST elevation in anterior leads V1 thro... |
SUBJECT: Metformin related adverse event report and clinical inquiry
BODY:
Dear Medical Affairs and Pharmacovigilance Team,
I am a charge nurse reporting on behalf of a 29 year old male patient under our care who has been prescribed Metformin. Treatment was started approximately 14 days ago with 100 mg per day.
Approx... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "97%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Metformin, a non-company product, evidenced by profound weakness, nausea, abdominal discomfort, and Kussmaul respirations... |
SUBJECT: Side effects from Ibuprofen and a dosing question
BODY:
Dear Clinical and Product Safety Teams,
I am a plastic surgeon writing on behalf of a 65 year old female patient who has been on Ibuprofen. The therapy was initiated 14 days ago at a dose of 30 mg.
Approximately 12 days ago, the patient began experiencin... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "94%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Ibuprofen, a non-company product, evidenced by progressive fatigue, pallor, recurrent infections, and bleeding with bone ... |
SUBJECT: Safety report and clinical guidance needed for Methotrexate adverse reaction
BODY:
Dear Medical Information and Regulatory Affairs Team,
I am a hospitalist writing on behalf of a 70 year old female patient who has been on Methotrexate. the patient has been on this medication for 7 weeks at 1000 mg daily.
Appr... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "97%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Methotrexate, a non-company product, evidenced by headache, visual disturbances, seizures, and altered mental status with... |
SUBJECT: Clinical query and adverse event notification - Lisinopril therapy
BODY:
Dear Healthcare Information and Quality Assurance Team,
I am a nurse practitioner reporting on behalf of a 52 year old male patient under our care who has been prescribed Lisinopril. Treatment was started approximately 8 weeks ago with 15... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "94%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Lisinopril, a non-company product, evidenced by flushing, urticaria, abdominal cramping, and hypotension of 76/44 mmHg wi... |
SUBJECT: Patient experiencing side effects on Metformin - medical information and adverse event documentation
BODY:
Dear Medical Information and Safety Team,
I am a cardiologist writing on behalf of a 75 year old male patient who has been on Metformin. The prescribed regimen is 12.5 mg and the patient commenced therapy... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "97%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Metformin, a non-company product, evidenced by complete loss of appetite, early satiety, and unintended weight loss of 8 ... |
SUBJECT: Patient safety concern and information request - Amlodipine related
BODY:
Dear Scientific Information and Supply Chain Teams,
I am a neonatologist writing on behalf of a 61 year old female patient who has been on Amlodipine. Treatment was started approximately 8 weeks ago with 5 mg per day.
Approximately 9 da... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "97%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Amlodipine, a non-company product, evidenced by bilateral pitting edema extending to the knees, with weight gain of 6 kg ... |
SUBJECT: Patient safety concern and information request - Omeprazole related
BODY:
Dear Medical Information and Product Integrity Team,
I am writing as the caregiver of a 19 year old female patient who is taking Omeprazole. The prescribed regimen is 100 mg and she commenced therapy 4 months ago.
During the past 4 days... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "95%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Omeprazole, a non-company product, evidenced by profuse watery diarrhea 14 times per day, fever of 38.5 C, leukocytosis o... |
SUBJECT: Safety report and clinical guidance needed for Amlodipine adverse reaction
BODY:
Dear Medical Information and Commercial Team,
I am a pathologist writing on behalf of a 55 year old female patient who has been on Amlodipine. the patient has been on this medication for 6 weeks at 100 mg daily.
During the past 1... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "95%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Amlodipine, a non-company product, evidenced by persistent facial erythema, warmth, and burning sensation resembling rosa... |
SUBJECT: Medical information request and adverse event report for Amlodipine
BODY:
Dear Medical Affairs and Pharmacovigilance Team,
I am a urologist writing on behalf of a 25 year old female patient who has been on Amlodipine. The therapy was initiated 5 months ago at a dose of 2.5 mg.
During the past 2 weeks, the pat... | {"Classification_of_request": {"Classification": "Adverse Event, Medical Information", "Confidence_percentage": "93%"}, "Analysis": "The email reports new adverse symptoms temporally associated with Amlodipine, a non-company product, evidenced by severe gingival overgrowth covering 60% of tooth surfaces causing bleedin... |
End of preview. Expand in Data Studio
Medical Emails Multi-Label Classification Dataset
This dataset contains 1000 synthetic medical emails for multi-label classification across 5 combined categories.
Categories (200 emails each)
| Category | Count | Description |
|---|---|---|
| Adverse Event + Medical Information | 200 | Emails reporting adverse symptoms while also requesting clinical/scientific information |
| Medical Information + Product Complaint | 200 | Emails requesting clinical guidance while also reporting product quality defects |
| Medical Information + Other | 200 | Emails requesting clinical information while also making B2B commercial inquiries |
| Adverse Event + Product Complaint | 200 | Emails reporting adverse reactions while also documenting product quality issues |
| All Four Combined | 200 | Emails containing adverse event, medical information request, product complaint, and B2B inquiry in a single message |
Non-Company Product X List
All emails reference one of these 9 non-company drugs:
- Metformin, Atorvastatin, Amoxicillin, Ibuprofen, Omeprazole, Lisinopril, Levothyroxine, Amlodipine, Methotrexate
Format
Strict JSONL with 2 fields per line:
instruction: Email subject and body (structured as "SUBJECT: ...\nBODY:\n...")output: JSON string containing classification result and analysis
Example
{"instruction":"SUBJECT: Side effects from Metformin and a dosing question\nBODY:\nDear Medical Information Team,\nI have been taking Metformin 500mg for my type 2 diabetes for approximately 3 weeks. Over the past 10 days I have been experiencing severe and persistent nausea...","output":"{\"Classification_of_request\": {\"Classification\": \"Adverse Event, Medical Information\", \"Confidence_percentage\": \"95%\"}, \"Analysis\": \"The email reports new adverse symptoms temporally associated with initiation of Metformin...\"}"}
Dataset Characteristics
- Total emails: 1000 (all unique)
- Senders: Mixed HCPs (physicians, nurses, pharmacists, specialists) and non-HCPs (patients, caregivers)
- Numeric normalization: All numbers written as digits (e.g., "45 year old", "500 mg", "3 weeks")
- No unicode escape characters: No
\u2013or similar escapes in the data - No parenthesis in analysis text
Generated by ML Intern
This dataset repository was generated by ML Intern, an agent for machine learning research and development on the Hugging Face Hub.
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Usage
from datasets import load_dataset
dataset = load_dataset('Ramesh10/medical-emails-multilabel-dataset')
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