conversations listlengths 2 2 |
|---|
[
{
"from": "human",
"value": "Question: Are group 2 innate lymphoid cells ( ILC2s ) increased in chronic rhinosinusitis with nasal polyps or eosinophilia?\nContext: {'contexts': ['Chronic rhinosinusitis (CRS) is a heterogeneous disease with an uncertain pathogenesis. Group 2 innate lymphoid cells (ILC2s) rep... |
[
{
"from": "human",
"value": "Question: Does vagus nerve contribute to the development of steatohepatitis and obesity in phosphatidylethanolamine N-methyltransferase deficient mice?\nContext: {'contexts': ['Phosphatidylethanolamine N-methyltransferase (PEMT), a liver enriched enzyme, is responsible for appro... |
[
{
"from": "human",
"value": "Question: Does psammaplin A induce Sirtuin 1-dependent autophagic cell death in doxorubicin-resistant MCF-7/adr human breast cancer cells and xenografts?\nContext: {'contexts': ['Psammaplin A (PsA) is a natural product isolated from marine sponges, which has been demonstrated to... |
[
{
"from": "human",
"value": "Question: Is methylation of the FGFR2 gene associated with high birth weight centile in humans?\nContext: {'contexts': ['This study examined links between DNA methylation and birth weight centile (BWC), and explored the impact of genetic variation.', 'Using HumanMethylation450 a... |
[
{
"from": "human",
"value": "Question: Do tumor-infiltrating immune cell profiles and their change after neoadjuvant chemotherapy predict response and prognosis of breast cancer?\nContext: {'contexts': ['Tumor microenvironment immunity is associated with breast cancer outcome. A high lymphocytic infiltratio... |
[
{
"from": "human",
"value": "Question: Is hidradenitis suppurativa a systemic disease with substantial comorbidity burden : a chart-verified case-control analysis?\nContext: {'contexts': ['Hidradenitis suppurativa (HS) is a chronic inflammatory disease involving intertriginous skin. Previous epidemiologic s... |
[
{
"from": "human",
"value": "Question: Does reference range for serum and salivary testosterone in young men of Mediterranean region?\nContext: {'contexts': ['The interassay variability found in the measurement of testosterone (T) levels warrants the need for laboratories to validate their methods to establ... |
[
{
"from": "human",
"value": "Question: Are secretory phospholipases A2 secreted from ciliated cells and increase mucin and eicosanoid secretion from goblet cells?\nContext: {'contexts': ['Secretory phospholipases A2 (sPLA2) initiate the biosynthesis of eicosanoids, are increased in the airways of people wit... |
[
{
"from": "human",
"value": "Question: Is admission hyperglycemia associated with failed reperfusion following fibrinolytic therapy in patients with STEMI : results of a retrospective study?\nContext: {'contexts': ['Hyperglycemia on admission is associated with increased mortality rates in patients with ST-... |
[
{
"from": "human",
"value": "Question: Do systematic Reviews Published in Emergency Medicine Journals Routinely Search Clinical Trials Registries : A Cross-Sectional Analysis?\nContext: {'contexts': ['Publication bias compromises the validity of systematic reviews. This problem can be addressed in part thro... |
[
{
"from": "human",
"value": "Question: Do obese patients with idiopathic pulmonary fibrosis have a higher 90-day mortality risk with bilateral lung transplantation?\nContext: {'contexts': ['Obese patients with idiopathic pulmonary fibrosis (IPF) have higher 90-day mortality after lung transplantation. We so... |
[
{
"from": "human",
"value": "Question: Does promoter variant rs2301228 on the neural cell adhesion molecule 1 gene confer risk of schizophrenia in Han Chinese?\nContext: {'contexts': ['Schizophrenia is recognized as a disorder of the brain and neuronal connectivity. The neural cell adhesion molecule 1 (NCAM... |
[
{
"from": "human",
"value": "Question: Are [ Higher nitric oxide levels associated with disease activity in Egyptian rheumatoid arthritis patients ]?\nContext: {'contexts': ['Oxidative stress generated within inflammatory joints can produce autoimmune phenomena and joint destruction. Radical species with ox... |
[
{
"from": "human",
"value": "Question: Does increased Syk phosphorylation lead to overexpression of TRAF6 in peripheral B cells of patients with systemic lupus erythematosus?\nContext: {'contexts': ['Activation of B cells is a hallmark of systemic lupus erythematosus (SLE). Syk and TRAF6 are key signaling m... |
[
{
"from": "human",
"value": "Question: Are reasons why erupted third molars extracted in a public university in Mexico?\nContext: {'contexts': ['The aim of this study was to determine the reasons for which erupted third molars (3M) are extracted in a sample of Mexican patients.', \"A retrospective cross-sec... |
[
{
"from": "human",
"value": "Question: Does the Boston keratoprosthesis provide a wide depth of focus?\nContext: {'contexts': ['To measure the through-focus curve for eyes implanted with a type 1 Boston keratoprosthesis (KPro) and compare it to that of pseudophakic controls with fixed pupil sizes. The resul... |
[
{
"from": "human",
"value": "Question: Do large portion sizes increase bite size and eating rate in overweight women?\nContext: {'contexts': ['Larger food portions lead to increased intake but the mechanism behind this effect is unclear. We investigated the effect of portion size on bite size, eating rate, ... |
[
{
"from": "human",
"value": "Question: Are routine preoperative restaging CTs after neoadjuvant chemoradiation for locally advanced rectal cancer low yield : a retrospective case study?\nContext: {'contexts': ['Pre-operative restaging CT scans are often performed routinely following neoadjuvant chemoradioth... |
[
{
"from": "human",
"value": "Question: Does pancreatic polypeptide regulate glucagon release through PPYR1 receptors expressed in mouse and human alpha-cells?\nContext: {'contexts': ['Plasma levels of pancreatic polypeptide (PP) rise upon food intake. Although other pancreatic islet hormones, such as insuli... |
[
{
"from": "human",
"value": "Question: Do two decades of British newspaper coverage regarding attempt cardiopulmonary resuscitation decisions : Lessons for clinicians?\nContext: {'contexts': ['To review UK newspaper reports relating to Do Not Attempt Cardiopulmonary Resuscitation (DNACPR) decisions in order... |
[
{
"from": "human",
"value": "Question: Is increased time from neoadjuvant chemoradiation to surgery associated with higher pathologic complete response rates in esophageal cancer?\nContext: {'contexts': ['The interval between neoadjuvant chemoradiation treatment and surgery has been described as an importan... |
[
{
"from": "human",
"value": "Question: Is epileptic focus localization based on resting state interictal MEG recordings feasible irrespective of the presence or absence of spikes?\nContext: {'contexts': ['To investigate whether epileptogenic focus localization is possible based on resting state connectivity... |
[
{
"from": "human",
"value": "Question: Does seminal Helicobacter pylori treatment improve sperm motility in infertile asthenozoospermic men?\nContext: {'contexts': ['To assess the effect of treatment of seminal Helicobacter pylori in infertile asthenozoospermic men.', 'In all, 223 infertile asthenozoospermi... |
[
{
"from": "human",
"value": "Question: Does a migrating ciliary gate compartmentalize the site of axoneme assembly in Drosophila spermatids?\nContext: {'contexts': ['In most cells, the cilium is formed within a compartment separated from the cytoplasm. Entry into the ciliary compartment is regulated by a sp... |
[
{
"from": "human",
"value": "Question: Is individual Public Transportation Accessibility Positively Associated with Self-Reported Active Commuting?\nContext: {'contexts': ['Active commuters have lower risk of chronic disease. Understanding which of the, to some extent, modifiable characteristics of public t... |
[
{
"from": "human",
"value": "Question: Is congenital penile pathology associated with abnormal development of the dartos muscle : a prospective study of primary penile surgery at a tertiary referral center?\nContext: {'contexts': ['Pathophysiological mechanisms leading to chordee in patients with hypospadia... |
[
{
"from": "human",
"value": "Question: Is δNp63 expression a protective factor of progression in clinical high grade T1 bladder cancer?\nContext: {'contexts': ['Several risk factors have been claimed to predict the progression of clinically high grade T1 bladder tumors. However, these factors are not specif... |
[
{
"from": "human",
"value": "Question: Do high levels of procalcitonin in the early phase after pediatric liver transplantation indicate poor postoperative outcome?\nContext: {'contexts': ['To date, no data is available about procalcitonin (PCT) levels and its relevance to morbidity and graft function in th... |
[
{
"from": "human",
"value": "Question: Is decreased expression of liver-type fatty acid-binding protein associated with poor prognosis in hepatocellular carcinoma?\nContext: {'contexts': ['The purpose of this study was to assess liver-type fatty acid-binding protein (L-FABP) expression and its association w... |
[
{
"from": "human",
"value": "Question: Does ephrin type-B receptor 4 activation reduce neointimal hyperplasia in human saphenous vein in vitro?\nContext: {'contexts': ['Vein bypass is an essential therapy for patients with advanced peripheral and coronary artery disease despite development of neointimal hyp... |
[
{
"from": "human",
"value": "Question: Are low serum levels of vitamin D associated with post-stroke depression?\nContext: {'contexts': ['Low serum levels of vitamin D have been associated with depression in non-stroke subjects. Our aim was to examine the possible association between serum vitamin D levels ... |
[
{
"from": "human",
"value": "Question: Are polymorphisms near TBX5 and GDF7 associated with increased risk for Barrett 's esophagus?\nContext: {'contexts': [\"Barrett's esophagus (BE) increases the risk of esophageal adenocarcinoma (EAC). We found the risk to be BE has been associated with single nucleotide... |
[
{
"from": "human",
"value": "Question: Does danzhi Xiaoyao San ameliorate depressive-like behavior by shifting toward serotonin via the downregulation of hippocampal indoleamine 2,3-dioxygenase?\nContext: {'contexts': ['Danzhi Xiaoyao San (DXS) is a canonical Chinese medicine formula from Principles of Inte... |
[
{
"from": "human",
"value": "Question: Is p63 more sensitive and specific than 34βE12 to differentiate adenocarcinoma of prostate from cancer mimickers?\nContext: {'contexts': [\"Prostate cancer is the world's leading cause of cancer and the second cause of cancer-related death in men after lung cancer. Dif... |
[
{
"from": "human",
"value": "Question: Does poor sleep predict symptoms of depression and disability retirement due to depression?\nContext: {'contexts': ['Disturbed sleep is associated with mood disorders. Both depression and insomnia may increase the risk of disability retirement. The longitudinal links a... |
[
{
"from": "human",
"value": "Question: Are phospholipase C epsilon 1 ( PLCE1 ) haplotypes associated with increased risk of gastric cancer in Kashmir Valley?\nContext: {'contexts': ['Phospholipase C epsilon 1 (PLCE1) plays a crucial role in carcinogenesis and progression of several types of cancers. A singl... |
[
{
"from": "human",
"value": "Question: Is tGFBI Expression in Cancer Stromal Cells Associated with Poor Prognosis and Hematogenous Recurrence in Esophageal Squamous Cell Carcinoma?\nContext: {'contexts': ['Esophageal squamous cell carcinoma (ESCC) is an important cause of cancer-related death worldwide. To ... |
[
{
"from": "human",
"value": "Question: Are autoimmune features associated with chronic antibiotic-refractory pouchitis?\nContext: {'contexts': ['Chronic antibiotic-refractory pouchitis (CARP) occurs more frequently in patients with ileal pouch-anal anastomosis (IPAA) with concomitant autoimmune disorders. T... |
[
{
"from": "human",
"value": "Question: Does identical ATP1A3 mutation cause alternating hemiplegia of childhood and rapid-onset dystonia parkinsonism phenotypes?\nContext: {'contexts': ['Alternating hemiplegia of childhood and rapid-onset dystonia parkinsonism are two separate movement disorders with differ... |
[
{
"from": "human",
"value": "Question: Does metabolic control analysis of the Trypanosoma cruzi peroxide detoxification pathway identify tryparedoxin as a suitable drug target?\nContext: {'contexts': ['The principal oxidative-stress defense in the human parasite Trypanosoma cruzi is the tryparedoxin-depende... |
[
{
"from": "human",
"value": "Question: Is basal Flt1 tyrosine kinase activity a positive regulator of endothelial survival and vascularization during zebrafish embryogenesis?\nContext: {'contexts': ['The role of Kdr (VEGFR-2/Flk-1) in vascular formation has been well described, but the role of Flt1 (VEGFR-1... |
[
{
"from": "human",
"value": "Question: Do immunizations with hepatitis B viral antigens and a TLR7/8 agonist adjuvant induce antigen-specific immune responses in HBV-transgenic mice?\nContext: {'contexts': ['The capacity of toll-like receptor (TLR) 7/8 agonist-conjugated hepatitis B virus (HBV) proteins (HB... |
[
{
"from": "human",
"value": "Question: Are lobar microbleeds associated with a decline in executive functioning in older adults?\nContext: {'contexts': [\"Normal aging is associated with a decline in cognitive abilities, particularly in the domains of psychomotor speed and executive functioning. However, 'a... |
[
{
"from": "human",
"value": "Question: Is self-reported physical activity in smoking pre-cessation a protective factor against relapse for all?\nContext: {'contexts': ['In recent years, the relationship between physical activity (PA) and smoking cessation has been increasingly studied. However, very few stu... |
[
{
"from": "human",
"value": "Question: Is breathlessness at rest the dominant presentation of patients admitted with heart failure?\nContext: {'contexts': ['Many assume that most patients hospitalized with heart failure (HF) are short of breath at rest (SOBAR). The National HF Audit for England and Wales su... |
[
{
"from": "human",
"value": "Question: Is delayed duodenal stump blow-out following total gastrectomy for cancer : Heightened awareness for the continued presence of the surgical past in the present the key to a successful duodenal stump disruption management . A case report?\nContext: {'contexts': ['Duoden... |
[
{
"from": "human",
"value": "Question: Are lipoprotein phospholipase A2 mass and activity associated with the diagnosis of acute brain ischemia?\nContext: {'contexts': ['Elevated lipoprotein-associated phospholipase A2 (Lp-PLA2) levels are associated with both coronary artery and cerebrovascular diseases. T... |
[
{
"from": "human",
"value": "Question: Is osteoprotegerin associated with subclinical left ventricular systolic dysfunction in diabetic hypertensive patients : a speckle tracking study?\nContext: {'contexts': ['Recently, the role of osteoprotegerin (OPG) in the pathogenesis of heart failure through differen... |
[
{
"from": "human",
"value": "Question: Do a new model for the standardization of experimental burn wounds?\nContext: {'contexts': ['Burns are common and recurrent events treated by physicians on a daily basis at most emergency rooms around the world. There is a constant need to understand the physiopatholog... |
[
{
"from": "human",
"value": "Question: Does circulating atrial natriuretic peptide genetic association study identify a novel gene cluster associated with stroke in whites?\nContext: {'contexts': ['The goal of this study was to identify genetic determinants of plasma N-terminal proatrial natriuretic peptide... |
[
{
"from": "human",
"value": "Question: Do whole-genome sequencing and epidemiological analysis provide evidence for cross-transmission of mycobacterium abscessus in a cohort of pediatric cystic fibrosis patients?\nContext: {'contexts': ['Mycobacterium abscessus has emerged as a major pathogen in cystic fibr... |
[
{
"from": "human",
"value": "Question: Are high Atopobium vaginae and Gardnerella vaginalis vaginal loads associated with preterm birth?\nContext: {'contexts': ['Bacterial vaginosis is a risk factor for preterm birth. The various conventional methods for its diagnosis are laborious and not easily reproducib... |
[
{
"from": "human",
"value": "Question: Is cD30 expression a novel prognostic indicator in extranodal natural killer/T-cell lymphoma , nasal type?\nContext: {'contexts': ['Extranodal natural killer/T-cell lymphoma, nasal type (ENKTL), is an aggressive type of lymphoma whose standard treatment and validated p... |
[
{
"from": "human",
"value": "Question: Do [ Clinical study on continuous plasma filtration absorption treatment for burn sepsis ]?\nContext: {'contexts': ['To observe the therapeutic effects of continuous plasma filtration absorption (CPFA) treatment on burn sepsis.', \"Thirty burn patients with sepsis hosp... |
[
{
"from": "human",
"value": "Question: Do [ Perinatal variables from newborns of Aymara mothers suggest a genetic adaptation to high altitude ]?\nContext: {'contexts': ['Studies performed in Andean populations living in high altitude, indicate that the reduced availability of oxygen could be associated to b... |
[
{
"from": "human",
"value": "Question: Is 25-hydroxyvitamin D status associated with chronic cerebral small vessel disease?\nContext: {'contexts': ['The aim of this study was to determine the association between 25-hydroxyvitamin D (25(OH)D) and neuroimaging correlates of cerebral small vessel disease.', 'W... |
[
{
"from": "human",
"value": "Question: Is cD133-positive tumor cell content a predictor of early recurrence in colorectal cancer?\nContext: {'contexts': ['The aims of this study were to demonstrate the tumorigenicity of CD133+ colon cancer cells in vitro, analyze the correlations between spheroid formation ... |
[
{
"from": "human",
"value": "Question: Does traumatic brain injury induce neuroinflammation and neuronal degeneration that is associated with escalated alcohol self-administration in rats?\nContext: {'contexts': ['Traumatic brain injury (TBI) affects millions of people each year and is characterized by dire... |
[
{
"from": "human",
"value": "Question: Does maternal undernutrition induce premature reproductive senescence in adult female rat offspring?\nContext: {'contexts': ['To determine the effects of maternal undernutrition (MUN) on the reproductive axis of aging offspring.', 'Animal (rat) study.', 'Research labor... |
[
{
"from": "human",
"value": "Question: Does granulocyte colony-stimulating factor prevent loss of spermatogenesis after sterilizing busulfan chemotherapy?\nContext: {'contexts': ['To determine whether granulocyte colony-stimulating factor (G-CSF) could prevent loss of spermatogenesis induced by busulfan che... |
[
{
"from": "human",
"value": "Question: Is saikosaponin b2 a naturally occurring terpenoid that efficiently inhibits hepatitis C virus entry?\nContext: {'contexts': ['A vaccine against hepatitis C virus (HCV) is unavailable and cost-effective antivirals that prevent HCV infection and re-infection, such as in... |
[
{
"from": "human",
"value": "Question: Does autotaxin activity have a high accuracy to diagnose intrahepatic cholestasis of pregnancy?\nContext: {'contexts': ['Intrahepatic cholestasis of pregnancy (ICP) is defined by pruritus, elevated total fasting serum bile salts (TBS) and transaminases, and an increase... |
[
{
"from": "human",
"value": "Question: Does a dedicated research program increase the quantity and quality of orthopaedic resident publications?\nContext: {'contexts': ['Programs seek to expose trainees to research during residency. However, little is known in any formal sense regarding how to do this effec... |
[
{
"from": "human",
"value": "Question: Does cationic Nanogel-mediated Runx2 and Osterix siRNA Delivery decrease Mineralization in MC3T3 Cells?\nContext: {'contexts': ['Heterotopic ossification (HO) may occur after musculoskeletal trauma, traumatic brain injury, and total joint arthroplasty. As such, HO is a... |
[
{
"from": "human",
"value": "Question: Do no sex differences exist in posterior condylar offsets of the knee?\nContext: {'contexts': ['Restoration of posterior condylar offset during TKA is believed to be important to improving knee kinematics, maximizing ROM, and minimizing flexion instability. However, co... |
[
{
"from": "human",
"value": "Question: Do gene polymorphisms of stress hormone and cytokine receptors associate with immunomodulatory profile and psychological measurement?\nContext: {'contexts': ['We sought to identify whether stable single nucleotide polymorphisms (SNPs) of various endocrine and immune mo... |
[
{
"from": "human",
"value": "Question: Does housing temperature influence the pattern of heat shock protein induction in mice following mild whole body hyperthermia?\nContext: {'contexts': ['Researchers studying the murine response to stress generally use mice housed under standard, nationally mandated cond... |
[
{
"from": "human",
"value": "Question: Does intra-articular injection of synthetic microRNA-210 accelerate avascular meniscal healing in rat medial meniscal injured model?\nContext: {'contexts': ['The important functions of the meniscus are shock absorption, passive stabilization and load transmission of th... |
[
{
"from": "human",
"value": "Question: Does pRMT5 enhance generation of induced pluripotent stem cells from dairy goat embryonic fibroblasts via down-regulation of p53?\nContext: {'contexts': ['Protein arginine methyltransferase 5 (PRMT5), is thought to play a role in epigenetic reprogramming of mouse germ ... |
[
{
"from": "human",
"value": "Question: Do minimally invasive retroperitoneoscopic surgery for psoas abscess with thoracolumbar tuberculosis?\nContext: {'contexts': ['Minimally invasive retroperitoneoscopic surgery (MIS) for psoas abscess (PA) in patients with thoracolumbar tuberculosis is not well-illustrat... |
[
{
"from": "human",
"value": "Question: Is cartilage thickness at the posterior medial femoral condyle increased in femorotibial knee osteoarthritis : a cross-sectional CT arthrography study ( Part 2 )?\nContext: {'contexts': ['To evaluate the thickness of cartilage at the posterior aspect of the medial and ... |
[
{
"from": "human",
"value": "Question: Does loss of Frzb and Sfrp1 differentially affect joint homeostasis in instability-induced osteoarthritis?\nContext: {'contexts': ['To investigate the specific role of Frizzled-related protein (FRZB) and Secreted frizzled-related protein 1 (SFRP1) in the onset and prog... |
[
{
"from": "human",
"value": "Question: Does tetraploid complementation prove pluripotency of induced pluripotent stem cells derived from adipose tissue?\nContext: {'contexts': ['Recently, pluripotency of induced pluripotent stem (iPS) cells has been displayed after producing adult mice, in tetraploid comple... |
[
{
"from": "human",
"value": "Question: Does implementation of the acute care surgery model provide benefits in the surgical treatment of the acute appendicitis?\nContext: {'contexts': ['Several reports have indicated the benefits of the acute care surgery (ACS) model in surgical outcomes. We tried to deline... |
[
{
"from": "human",
"value": "Question: Is radiofrequency ablation plus devascularization the preferred treatment of hepatocellular carcinoma with esophageal varices?\nContext: {'contexts': [\"Most hepatocellular carcinomas (HCCs) are associated with cirrhosis. Portal hypertension (PHT) and esophageal varice... |
[
{
"from": "human",
"value": "Question: Is enhancement of in vitro activity of tuberculosis drugs by addition of thioridazine reflected by improved in vivo therapeutic efficacy?\nContext: {'contexts': ['Assessment of the activity of thioridazine towards Mycobacterium tuberculosis (Mtb), in\\xa0vitro and in\\... |
[
{
"from": "human",
"value": "Question: Do youth walking and biking rates vary by environments around 5 Louisiana schools?\nContext: {'contexts': [\"The prevalence of obesity in children is high, and many do not meet physical activity recommendations. The Safe Routes to School (SRTS) program encourages schoo... |
[
{
"from": "human",
"value": "Question: Does blockade of Central Angiotensin II AT1 Receptor protect the Brain from Ischemia/Reperfusion Injury in Normotensive Rats?\nContext: {'contexts': ['Stroke is the third leading cause of invalidism and death in industrialized countries. There are conflicting reports a... |
[
{
"from": "human",
"value": "Question: Does syngap1 haploinsufficiency damage a postnatal critical period of pyramidal cell structural maturation linked to cortical circuit assembly?\nContext: {'contexts': ['Genetic haploinsufficiency of SYNGAP1/Syngap1 commonly occurs in developmental brain disorders, such... |
[
{
"from": "human",
"value": "Question: Is pentraxin 3 reduced in bipolar disorder?\nContext: {'contexts': ['Immunologic abnormalities have been found in bipolar disorder but pentraxin 3, a marker of innate immunity, has not been studied in this population.', 'Levels of pentraxin 3 were measured in individua... |
[
{
"from": "human",
"value": "Question: Are human enteroviruses the cause of neurological impairments in children at the Korle-Bu Teaching Hospital?\nContext: {'contexts': ['Convulsions associated with fever and acute onset of unknown aetiology with case fatalities have become a long observed medical conditi... |
[
{
"from": "human",
"value": "Question: Does a whole blood-based perfusate provide superior preservation of myocardial function during ex vivo heart perfusion?\nContext: {'contexts': ['Ex vivo heart perfusion (EVHP) provides the opportunity to resuscitate unused donor organs and facilitates assessments of my... |
[
{
"from": "human",
"value": "Question: Is elevated immune monitoring early after cardiac transplantation associated with increased plaque progression by intravascular ultrasound?\nContext: {'contexts': ['Immune monitoring (IM) has not been shown to be associated with cardiac allograft vasculopathy (CAV).', ... |
[
{
"from": "human",
"value": "Question: Are successional changes in the chicken cecal microbiome during 42 days of growth independent of organic acid feed additives?\nContext: {'contexts': ['Poultry remains a major source of foodborne bacterial infections. A variety of additives with presumed anti-microbial ... |
[
{
"from": "human",
"value": "Question: Does resveratrol enhance palmitate-induced ER stress and apoptosis in cancer cells?\nContext: {'contexts': ['Palmitate, a saturated fatty acid (FA), is known to induce toxicity and cell death in various types of cells. Resveratrol (RSV) is able to prevent pathogenesis ... |
[
{
"from": "human",
"value": "Question: Is cDK1 and CDK2 activity a strong predictor of renal cell carcinoma recurrence?\nContext: {'contexts': ['In renal cell carcinoma (RCC), the prediction of metastasis via tumor prognostic markers remains a major problem. The objective of our study was to evaluate the ef... |
[
{
"from": "human",
"value": "Question: Is torsion of the optic nerve head a prominent feature of normal-tension glaucoma?\nContext: {'contexts': ['To compare optic nerve head (ONH) morphology between eyes with normal-tension glaucoma (NTG) and primary open-angle glaucoma (POAG).', 'Seventy-eight NTG patient... |
[
{
"from": "human",
"value": "Question: Is endo first appropriate in some patients with critical limb ischemia because `` bridges are burned ''?\nContext: {'contexts': ['The aims of this study were to determine the effect of failed prior endovascular treatment (EV) on early and midterm outcomes of subsequent... |
[
{
"from": "human",
"value": "Question: Is unrecognized arteriosclerosis associated with wound complications after below-knee amputation?\nContext: {'contexts': ['Guillotine below-knee amputation (BKA) for wet gangrene is an unfortunate complication of poorly controlled diabetes. We examined risk factors ass... |
[
{
"from": "human",
"value": "Question: Does hydrogen sulfide reduce inflammation following abdominal aortic occlusion in rats?\nContext: {'contexts': ['Remote renal ischemia-reperfusion injury (IRI) following infra-renal aortic occlusion leads to acute kidney injury and systemic inflammation. Hydrogen sulfi... |
[
{
"from": "human",
"value": "Question: Do seed bank dynamics govern persistence of Brassica hybrids in crop and natural habitats?\nContext: {'contexts': ['Gene flow from crops to their wild relatives has the potential to alter population growth rates and demography of hybrid populations, especially when a n... |
[
{
"from": "human",
"value": "Question: Is actinic keratosis with atypical basal cells ( AK I ) the most common lesion associated with invasive squamous cell carcinoma of the skin?\nContext: {'contexts': [\"Progression from actinic keratosis (AK) to invasive squamous cell carcinoma (iSCC) of the skin is thou... |
[
{
"from": "human",
"value": "Question: Does high-intensity intermittent exercise increase pulmonary interstitial edema at altitude but not at simulated altitude?\nContext: {'contexts': ['Ascent to high altitude leads to a reduction in ambient pressure and a subsequent fall in available oxygen. The resulting... |
[
{
"from": "human",
"value": "Question: Does mild cognitive dysfunction affect diabetes mellitus control in minority elderly adults?\nContext: {'contexts': ['To determine whether older adults with type 2 diabetes mellitus and cognitive dysfunction have poorer metabolic control of glycosylated hemoglobin, sys... |
[
{
"from": "human",
"value": "Question: Are anti-high mobility group box 1 ( anti-HMGB1 ) antibodies related to the occurrence of cutaneous lesions in systemic lupus erythematosus?\nContext: {'contexts': ['To investigate whether serum anti-high mobility group box 1 (anti-HMGB1) antibodies are related to the ... |
[
{
"from": "human",
"value": "Question: Does alcohol disrupt levels and function of the cystic fibrosis transmembrane conductance regulator to promote development of pancreatitis?\nContext: {'contexts': ['Excessive consumption of ethanol is one of the most common causes of acute and chronic pancreatitis. Alt... |
[
{
"from": "human",
"value": "Question: Does blood viscosity but not shear stress associate with delayed flow-mediated dilation?\nContext: {'contexts': ['Flow-mediated dilation (FMD) is a complex mechanism involving several mediators, and different hemodynamic forces. Temporally distinct FMD patterns can be ... |
[
{
"from": "human",
"value": "Question: Does hypercholesterolemia increase the production of leukotriene B4 in neutrophils by enhancing the nuclear localization of 5-lipoxygenase?\nContext: {'contexts': ['Neutrophils can synthesize leukotriene B4 (LTB4) by activating the 5-lipoxygenase (5-LO)signaling pathwa... |
[
{
"from": "human",
"value": "Question: Do molecular signatures of mood stabilisers highlight the role of the transcription factor REST/NRSF?\nContext: {'contexts': ['The purpose of this study was to address the affects of mood modifying drugs on the transcriptome, in a tissue culture model, using qPCR array... |
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