sequence stringlengths 4 17.9k | seq_id stringlengths 1 6 | pn stringclasses 996
values | title stringclasses 871
values | pbdt int64 20.2M 20.3M | status int64 1 225 ⌀ | family_country listlengths 1 55 | modified_info stringlengths 112 8.31k ⌀ |
|---|---|---|---|---|---|---|---|
ctgtccaaggaaacttgaata | 2801 | EP4416284A1 | COMPOSITIONS D'ARNI À ADMINISTRATION EXTRA-HÉPATIQUE ET LEURS PROCÉDÉS D'UTILISATION | 20,240,821 | 1 | [
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] | [{"norInfos":[{"sourceData":"OTHER","norInfo":[{"modificationType":"Other"}]},{"sourceData":"2'-O-methylcytidine-3'-phosphorothioate","norInfo":[{"modificationType":"Non natural base","modification":["cm"]},{"modificationType":"Chemical","modification":["Phosphorothioate"]}]}],"locations":["1->1"],"infos":["OTHER","2'-... |
acattaaatttcttcaagcagtc | 5027 | EP4416284A1 | Extra-hepatic delivery irna compositions and methods of use thereof | 20,240,821 | 1 | [
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acattaaatttcttcaagcagtc | 5027 | EP4416284A1 | EXTRAHEPATISCHE IRNA-ZUSAMMENSETZUNGEN ZUR ABGABE UND VERFAHREN ZUR VERWENDUNG DAVON | 20,240,821 | 1 | [
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] | [{"norInfos":[{"sourceData":"OTHER","norInfo":[{"modificationType":"Other"}]},{"sourceData":"2'-O-methyladenosine-3'-phosphorothioate","norInfo":[{"modificationType":"Chemical","modification":["Phosphorothioate","2'-O-methyl"]}]}],"locations":["1->1"],"infos":["OTHER","2'-O-methyladenosine-3'-phosphorothioate"]},{"norI... |
acattaaatttcttcaagcagtc | 5027 | EP4416284A1 | COMPOSITIONS D'ARNI À ADMINISTRATION EXTRA-HÉPATIQUE ET LEURS PROCÉDÉS D'UTILISATION | 20,240,821 | 1 | [
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] | [{"norInfos":[{"sourceData":"OTHER","norInfo":[{"modificationType":"Other"}]},{"sourceData":"2'-O-methyladenosine-3'-phosphorothioate","norInfo":[{"modificationType":"Chemical","modification":["Phosphorothioate","2'-O-methyl"]}]}],"locations":["1->1"],"infos":["OTHER","2'-O-methyladenosine-3'-phosphorothioate"]},{"norI... |
acattaaatttcttcaagcagtc | 5572 | EP4416284A1 | Extra-hepatic delivery irna compositions and methods of use thereof | 20,240,821 | 1 | [
"JP",
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"EA",
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"EP",
"WO",
"HK",
"IL",
"ZA",
"CA",
"KR"
] | null |
acattaaatttcttcaagcagtc | 5572 | EP4416284A1 | EXTRAHEPATISCHE IRNA-ZUSAMMENSETZUNGEN ZUR ABGABE UND VERFAHREN ZUR VERWENDUNG DAVON | 20,240,821 | 1 | [
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"WO",
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"CA",
"KR"
] | null |
acattaaatttcttcaagcagtc | 5572 | EP4416284A1 | COMPOSITIONS D'ARNI À ADMINISTRATION EXTRA-HÉPATIQUE ET LEURS PROCÉDÉS D'UTILISATION | 20,240,821 | 1 | [
"JP",
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"IN",
"US",
"EP",
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"CA",
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] | null |
acattaaatttcttcaagcagtc | 4667 | EP4416284A1 | Extra-hepatic delivery irna compositions and methods of use thereof | 20,240,821 | 1 | [
"JP",
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"EA",
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"IN",
"US",
"EP",
"WO",
"HK",
"IL",
"ZA",
"CA",
"KR"
] | null |
acattaaatttcttcaagcagtc | 4667 | EP4416284A1 | EXTRAHEPATISCHE IRNA-ZUSAMMENSETZUNGEN ZUR ABGABE UND VERFAHREN ZUR VERWENDUNG DAVON | 20,240,821 | 1 | [
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"IN",
"US",
"EP",
"WO",
"HK",
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"ZA",
"CA",
"KR"
] | null |
acattaaatttcttcaagcagtc | 4667 | EP4416284A1 | COMPOSITIONS D'ARNI À ADMINISTRATION EXTRA-HÉPATIQUE ET LEURS PROCÉDÉS D'UTILISATION | 20,240,821 | 1 | [
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"EP",
"WO",
"HK",
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"ZA",
"CA",
"KR"
] | null |
acattaaatttcttcaagcagtc | 5932 | EP4416284A1 | Extra-hepatic delivery irna compositions and methods of use thereof | 20,240,821 | 1 | [
"JP",
"NZ",
"EA",
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] | [{"norInfos":[{"sourceData":"OTHER","norInfo":[{"modificationType":"Other"}]},{"sourceData":"2'-O-methyladenosine-3'-phosphorothioate","norInfo":[{"modificationType":"Chemical","modification":["Phosphorothioate","2'-O-methyl"]}]}],"locations":["1->1"],"infos":["OTHER","2'-O-methyladenosine-3'-phosphorothioate"]},{"norI... |
acattaaatttcttcaagcagtc | 5932 | EP4416284A1 | EXTRAHEPATISCHE IRNA-ZUSAMMENSETZUNGEN ZUR ABGABE UND VERFAHREN ZUR VERWENDUNG DAVON | 20,240,821 | 1 | [
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] | [{"norInfos":[{"sourceData":"OTHER","norInfo":[{"modificationType":"Other"}]},{"sourceData":"2'-O-methyladenosine-3'-phosphorothioate","norInfo":[{"modificationType":"Chemical","modification":["Phosphorothioate","2'-O-methyl"]}]}],"locations":["1->1"],"infos":["OTHER","2'-O-methyladenosine-3'-phosphorothioate"]},{"norI... |
acattaaatttcttcaagcagtc | 5932 | EP4416284A1 | COMPOSITIONS D'ARNI À ADMINISTRATION EXTRA-HÉPATIQUE ET LEURS PROCÉDÉS D'UTILISATION | 20,240,821 | 1 | [
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] | [{"norInfos":[{"sourceData":"OTHER","norInfo":[{"modificationType":"Other"}]},{"sourceData":"2'-O-methyladenosine-3'-phosphorothioate","norInfo":[{"modificationType":"Chemical","modification":["Phosphorothioate","2'-O-methyl"]}]}],"locations":["1->1"],"infos":["OTHER","2'-O-methyladenosine-3'-phosphorothioate"]},{"norI... |
ttaaaaaggtattttcccaatga | 775 | EP4416284A1 | Extra-hepatic delivery irna compositions and methods of use thereof | 20,240,821 | 1 | [
"JP",
"NZ",
"EA",
"SG",
"CN",
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"AU",
"IN",
"US",
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"WO",
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] | [{"norInfos":[{"sourceData":"OTHER","norInfo":[{"modificationType":"Other"}]},{"sourceData":"2'-O-methyluridine-3'-phosphorothioate 5'-(E)-Vinylphosphonate","norInfo":[{"modificationType":"Non natural base","modification":["um"]},{"modificationType":"Chemical","modification":["Phosphorothioate"]}]}],"locations":["1->1"... |
ttaaaaaggtattttcccaatga | 775 | EP4416284A1 | EXTRAHEPATISCHE IRNA-ZUSAMMENSETZUNGEN ZUR ABGABE UND VERFAHREN ZUR VERWENDUNG DAVON | 20,240,821 | 1 | [
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] | [{"norInfos":[{"sourceData":"OTHER","norInfo":[{"modificationType":"Other"}]},{"sourceData":"2'-O-methyluridine-3'-phosphorothioate 5'-(E)-Vinylphosphonate","norInfo":[{"modificationType":"Non natural base","modification":["um"]},{"modificationType":"Chemical","modification":["Phosphorothioate"]}]}],"locations":["1->1"... |
ttaaaaaggtattttcccaatga | 775 | EP4416284A1 | COMPOSITIONS D'ARNI À ADMINISTRATION EXTRA-HÉPATIQUE ET LEURS PROCÉDÉS D'UTILISATION | 20,240,821 | 1 | [
"JP",
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] | [{"norInfos":[{"sourceData":"OTHER","norInfo":[{"modificationType":"Other"}]},{"sourceData":"2'-O-methyluridine-3'-phosphorothioate 5'-(E)-Vinylphosphonate","norInfo":[{"modificationType":"Non natural base","modification":["um"]},{"modificationType":"Chemical","modification":["Phosphorothioate"]}]}],"locations":["1->1"... |
ttaaaaaggtattttcccaatga | 505 | EP4416284A1 | Extra-hepatic delivery irna compositions and methods of use thereof | 20,240,821 | 1 | [
"JP",
"NZ",
"EA",
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"CN",
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"IN",
"US",
"EP",
"WO",
"HK",
"IL",
"ZA",
"CA",
"KR"
] | null |
ttaaaaaggtattttcccaatga | 505 | EP4416284A1 | EXTRAHEPATISCHE IRNA-ZUSAMMENSETZUNGEN ZUR ABGABE UND VERFAHREN ZUR VERWENDUNG DAVON | 20,240,821 | 1 | [
"JP",
"NZ",
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"AU",
"IN",
"US",
"EP",
"WO",
"HK",
"IL",
"ZA",
"CA",
"KR"
] | null |
ttaaaaaggtattttcccaatga | 505 | EP4416284A1 | COMPOSITIONS D'ARNI À ADMINISTRATION EXTRA-HÉPATIQUE ET LEURS PROCÉDÉS D'UTILISATION | 20,240,821 | 1 | [
"JP",
"NZ",
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"IN",
"US",
"EP",
"WO",
"HK",
"IL",
"ZA",
"CA",
"KR"
] | null |
ttaatgtttattgggtgagcttc | 2938 | EP4416284A1 | Extra-hepatic delivery irna compositions and methods of use thereof | 20,240,821 | 1 | [
"JP",
"NZ",
"EA",
"SG",
"CN",
"MX",
"AU",
"IN",
"US",
"EP",
"WO",
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"CA",
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] | [{"norInfos":[{"sourceData":"OTHER","norInfo":[{"modificationType":"Other"}]},{"sourceData":"2'-O-methyluridine-3'-phosphorothioate 5'-(E)-Vinylphosphonate","norInfo":[{"modificationType":"Non natural base","modification":["um"]},{"modificationType":"Chemical","modification":["Phosphorothioate"]}]}],"locations":["1->1"... |
ttaatgtttattgggtgagcttc | 2938 | EP4416284A1 | EXTRAHEPATISCHE IRNA-ZUSAMMENSETZUNGEN ZUR ABGABE UND VERFAHREN ZUR VERWENDUNG DAVON | 20,240,821 | 1 | [
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] | [{"norInfos":[{"sourceData":"OTHER","norInfo":[{"modificationType":"Other"}]},{"sourceData":"2'-O-methyluridine-3'-phosphorothioate 5'-(E)-Vinylphosphonate","norInfo":[{"modificationType":"Non natural base","modification":["um"]},{"modificationType":"Chemical","modification":["Phosphorothioate"]}]}],"locations":["1->1"... |
ttaatgtttattgggtgagcttc | 2938 | EP4416284A1 | COMPOSITIONS D'ARNI À ADMINISTRATION EXTRA-HÉPATIQUE ET LEURS PROCÉDÉS D'UTILISATION | 20,240,821 | 1 | [
"JP",
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] | [{"norInfos":[{"sourceData":"OTHER","norInfo":[{"modificationType":"Other"}]},{"sourceData":"2'-O-methyluridine-3'-phosphorothioate 5'-(E)-Vinylphosphonate","norInfo":[{"modificationType":"Non natural base","modification":["um"]},{"modificationType":"Chemical","modification":["Phosphorothioate"]}]}],"locations":["1->1"... |
ttaatgtttattgggtgagcttc | 1945 | EP4416284A1 | Extra-hepatic delivery irna compositions and methods of use thereof | 20,240,821 | 1 | [
"JP",
"NZ",
"EA",
"SG",
"CN",
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"IN",
"US",
"EP",
"WO",
"HK",
"IL",
"ZA",
"CA",
"KR"
] | null |
ttaatgtttattgggtgagcttc | 1945 | EP4416284A1 | EXTRAHEPATISCHE IRNA-ZUSAMMENSETZUNGEN ZUR ABGABE UND VERFAHREN ZUR VERWENDUNG DAVON | 20,240,821 | 1 | [
"JP",
"NZ",
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"AU",
"IN",
"US",
"EP",
"WO",
"HK",
"IL",
"ZA",
"CA",
"KR"
] | null |
ttaatgtttattgggtgagcttc | 1945 | EP4416284A1 | COMPOSITIONS D'ARNI À ADMINISTRATION EXTRA-HÉPATIQUE ET LEURS PROCÉDÉS D'UTILISATION | 20,240,821 | 1 | [
"JP",
"NZ",
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"AU",
"IN",
"US",
"EP",
"WO",
"HK",
"IL",
"ZA",
"CA",
"KR"
] | null |
ttaatgtttattgggtgagcttc | 2213 | EP4416284A1 | Extra-hepatic delivery irna compositions and methods of use thereof | 20,240,821 | 1 | [
"JP",
"NZ",
"EA",
"SG",
"CN",
"MX",
"AU",
"IN",
"US",
"EP",
"WO",
"HK",
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"ZA",
"CA",
"KR"
] | [{"norInfos":[{"sourceData":"OTHER","norInfo":[{"modificationType":"Other"}]},{"sourceData":"2'-O-methyluridine-3'-phosphorothioate 5'-(E)-Vinylphosphonate","norInfo":[{"modificationType":"Non natural base","modification":["um"]},{"modificationType":"Chemical","modification":["Phosphorothioate"]}]}],"locations":["1->1"... |
ttaatgtttattgggtgagcttc | 2213 | EP4416284A1 | EXTRAHEPATISCHE IRNA-ZUSAMMENSETZUNGEN ZUR ABGABE UND VERFAHREN ZUR VERWENDUNG DAVON | 20,240,821 | 1 | [
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] | [{"norInfos":[{"sourceData":"OTHER","norInfo":[{"modificationType":"Other"}]},{"sourceData":"2'-O-methyluridine-3'-phosphorothioate 5'-(E)-Vinylphosphonate","norInfo":[{"modificationType":"Non natural base","modification":["um"]},{"modificationType":"Chemical","modification":["Phosphorothioate"]}]}],"locations":["1->1"... |
ttaatgtttattgggtgagcttc | 2213 | EP4416284A1 | COMPOSITIONS D'ARNI À ADMINISTRATION EXTRA-HÉPATIQUE ET LEURS PROCÉDÉS D'UTILISATION | 20,240,821 | 1 | [
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] | [{"norInfos":[{"sourceData":"OTHER","norInfo":[{"modificationType":"Other"}]},{"sourceData":"2'-O-methyluridine-3'-phosphorothioate 5'-(E)-Vinylphosphonate","norInfo":[{"modificationType":"Non natural base","modification":["um"]},{"modificationType":"Chemical","modification":["Phosphorothioate"]}]}],"locations":["1->1"... |
ttaatgtttattgggtgagcttc | 2672 | EP4416284A1 | Extra-hepatic delivery irna compositions and methods of use thereof | 20,240,821 | 1 | [
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"EA",
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"IN",
"US",
"EP",
"WO",
"HK",
"IL",
"ZA",
"CA",
"KR"
] | null |
ttaatgtttattgggtgagcttc | 2672 | EP4416284A1 | EXTRAHEPATISCHE IRNA-ZUSAMMENSETZUNGEN ZUR ABGABE UND VERFAHREN ZUR VERWENDUNG DAVON | 20,240,821 | 1 | [
"JP",
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"IN",
"US",
"EP",
"WO",
"HK",
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"ZA",
"CA",
"KR"
] | null |
ttaatgtttattgggtgagcttc | 2672 | EP4416284A1 | COMPOSITIONS D'ARNI À ADMINISTRATION EXTRA-HÉPATIQUE ET LEURS PROCÉDÉS D'UTILISATION | 20,240,821 | 1 | [
"JP",
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"IN",
"US",
"EP",
"WO",
"HK",
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"ZA",
"CA",
"KR"
] | null |
gtttttactccagtggtgaaa | 2793 | EP4416284A1 | Extra-hepatic delivery irna compositions and methods of use thereof | 20,240,821 | 1 | [
"JP",
"NZ",
"EA",
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"IN",
"US",
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] | [{"norInfos":[{"sourceData":"OTHER","norInfo":[{"modificationType":"Other"}]},{"sourceData":"2'-O-methylguanosine-3'-phosphorothioate","norInfo":[{"modificationType":"Non natural base","modification":["gm"]},{"modificationType":"Chemical","modification":["Phosphorothioate","2'-O-methyl"]}]}],"locations":["1->1"],"infos... |
gtttttactccagtggtgaaa | 2793 | EP4416284A1 | EXTRAHEPATISCHE IRNA-ZUSAMMENSETZUNGEN ZUR ABGABE UND VERFAHREN ZUR VERWENDUNG DAVON | 20,240,821 | 1 | [
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] | [{"norInfos":[{"sourceData":"OTHER","norInfo":[{"modificationType":"Other"}]},{"sourceData":"2'-O-methylguanosine-3'-phosphorothioate","norInfo":[{"modificationType":"Non natural base","modification":["gm"]},{"modificationType":"Chemical","modification":["Phosphorothioate","2'-O-methyl"]}]}],"locations":["1->1"],"infos... |
gtttttactccagtggtgaaa | 2793 | EP4416284A1 | COMPOSITIONS D'ARNI À ADMINISTRATION EXTRA-HÉPATIQUE ET LEURS PROCÉDÉS D'UTILISATION | 20,240,821 | 1 | [
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] | [{"norInfos":[{"sourceData":"OTHER","norInfo":[{"modificationType":"Other"}]},{"sourceData":"2'-O-methylguanosine-3'-phosphorothioate","norInfo":[{"modificationType":"Non natural base","modification":["gm"]},{"modificationType":"Chemical","modification":["Phosphorothioate","2'-O-methyl"]}]}],"locations":["1->1"],"infos... |
gtttttactccagtggtgaaa | 2527 | EP4416284A1 | Extra-hepatic delivery irna compositions and methods of use thereof | 20,240,821 | 1 | [
"JP",
"NZ",
"EA",
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"AU",
"IN",
"US",
"EP",
"WO",
"HK",
"IL",
"ZA",
"CA",
"KR"
] | null |
gtttttactccagtggtgaaa | 2527 | EP4416284A1 | EXTRAHEPATISCHE IRNA-ZUSAMMENSETZUNGEN ZUR ABGABE UND VERFAHREN ZUR VERWENDUNG DAVON | 20,240,821 | 1 | [
"JP",
"NZ",
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"AU",
"IN",
"US",
"EP",
"WO",
"HK",
"IL",
"ZA",
"CA",
"KR"
] | null |
gtttttactccagtggtgaaa | 2527 | EP4416284A1 | COMPOSITIONS D'ARNI À ADMINISTRATION EXTRA-HÉPATIQUE ET LEURS PROCÉDÉS D'UTILISATION | 20,240,821 | 1 | [
"JP",
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"EA",
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"AU",
"IN",
"US",
"EP",
"WO",
"HK",
"IL",
"ZA",
"CA",
"KR"
] | null |
gtttttactccagtggtgaaa | 1872 | EP4416284A1 | Extra-hepatic delivery irna compositions and methods of use thereof | 20,240,821 | 1 | [
"JP",
"NZ",
"EA",
"SG",
"CN",
"MX",
"AU",
"IN",
"US",
"EP",
"WO",
"HK",
"IL",
"ZA",
"CA",
"KR"
] | null |
gtttttactccagtggtgaaa | 1872 | EP4416284A1 | EXTRAHEPATISCHE IRNA-ZUSAMMENSETZUNGEN ZUR ABGABE UND VERFAHREN ZUR VERWENDUNG DAVON | 20,240,821 | 1 | [
"JP",
"NZ",
"EA",
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"MX",
"AU",
"IN",
"US",
"EP",
"WO",
"HK",
"IL",
"ZA",
"CA",
"KR"
] | null |
gtttttactccagtggtgaaa | 1872 | EP4416284A1 | COMPOSITIONS D'ARNI À ADMINISTRATION EXTRA-HÉPATIQUE ET LEURS PROCÉDÉS D'UTILISATION | 20,240,821 | 1 | [
"JP",
"NZ",
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"AU",
"IN",
"US",
"EP",
"WO",
"HK",
"IL",
"ZA",
"CA",
"KR"
] | null |
gtttttactccagtggtgaaa | 2140 | EP4416284A1 | Extra-hepatic delivery irna compositions and methods of use thereof | 20,240,821 | 1 | [
"JP",
"NZ",
"EA",
"SG",
"CN",
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"ZA",
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] | [{"norInfos":[{"sourceData":"OTHER","norInfo":[{"modificationType":"Other"}]},{"sourceData":"2'-O-methylguanosine-3'-phosphorothioate","norInfo":[{"modificationType":"Non natural base","modification":["gm"]},{"modificationType":"Chemical","modification":["Phosphorothioate","2'-O-methyl"]}]}],"locations":["1->1"],"infos... |
gtttttactccagtggtgaaa | 2140 | EP4416284A1 | EXTRAHEPATISCHE IRNA-ZUSAMMENSETZUNGEN ZUR ABGABE UND VERFAHREN ZUR VERWENDUNG DAVON | 20,240,821 | 1 | [
"JP",
"NZ",
"EA",
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] | [{"norInfos":[{"sourceData":"OTHER","norInfo":[{"modificationType":"Other"}]},{"sourceData":"2'-O-methylguanosine-3'-phosphorothioate","norInfo":[{"modificationType":"Non natural base","modification":["gm"]},{"modificationType":"Chemical","modification":["Phosphorothioate","2'-O-methyl"]}]}],"locations":["1->1"],"infos... |
gtttttactccagtggtgaaa | 2140 | EP4416284A1 | COMPOSITIONS D'ARNI À ADMINISTRATION EXTRA-HÉPATIQUE ET LEURS PROCÉDÉS D'UTILISATION | 20,240,821 | 1 | [
"JP",
"NZ",
"EA",
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] | [{"norInfos":[{"sourceData":"OTHER","norInfo":[{"modificationType":"Other"}]},{"sourceData":"2'-O-methylguanosine-3'-phosphorothioate","norInfo":[{"modificationType":"Non natural base","modification":["gm"]},{"modificationType":"Chemical","modification":["Phosphorothioate","2'-O-methyl"]}]}],"locations":["1->1"],"infos... |
ctgtgtttacttaagaccgatag | 917 | EP4416284A1 | Extra-hepatic delivery irna compositions and methods of use thereof | 20,240,821 | 1 | [
"JP",
"NZ",
"EA",
"SG",
"CN",
"MX",
"AU",
"IN",
"US",
"EP",
"WO",
"HK",
"IL",
"ZA",
"CA",
"KR"
] | null |
ctgtgtttacttaagaccgatag | 917 | EP4416284A1 | EXTRAHEPATISCHE IRNA-ZUSAMMENSETZUNGEN ZUR ABGABE UND VERFAHREN ZUR VERWENDUNG DAVON | 20,240,821 | 1 | [
"JP",
"NZ",
"EA",
"SG",
"CN",
"MX",
"AU",
"IN",
"US",
"EP",
"WO",
"HK",
"IL",
"ZA",
"CA",
"KR"
] | null |
ctgtgtttacttaagaccgatag | 917 | EP4416284A1 | COMPOSITIONS D'ARNI À ADMINISTRATION EXTRA-HÉPATIQUE ET LEURS PROCÉDÉS D'UTILISATION | 20,240,821 | 1 | [
"JP",
"NZ",
"EA",
"SG",
"CN",
"MX",
"AU",
"IN",
"US",
"EP",
"WO",
"HK",
"IL",
"ZA",
"CA",
"KR"
] | null |
ctgtgtttacttaagaccgatag | 1631 | EP4416284A1 | Extra-hepatic delivery irna compositions and methods of use thereof | 20,240,821 | 1 | [
"JP",
"NZ",
"EA",
"SG",
"CN",
"MX",
"AU",
"IN",
"US",
"EP",
"WO",
"HK",
"IL",
"ZA",
"CA",
"KR"
] | null |
ctgtgtttacttaagaccgatag | 1631 | EP4416284A1 | EXTRAHEPATISCHE IRNA-ZUSAMMENSETZUNGEN ZUR ABGABE UND VERFAHREN ZUR VERWENDUNG DAVON | 20,240,821 | 1 | [
"JP",
"NZ",
"EA",
"SG",
"CN",
"MX",
"AU",
"IN",
"US",
"EP",
"WO",
"HK",
"IL",
"ZA",
"CA",
"KR"
] | null |
ctgtgtttacttaagaccgatag | 1631 | EP4416284A1 | COMPOSITIONS D'ARNI À ADMINISTRATION EXTRA-HÉPATIQUE ET LEURS PROCÉDÉS D'UTILISATION | 20,240,821 | 1 | [
"JP",
"NZ",
"EA",
"SG",
"CN",
"MX",
"AU",
"IN",
"US",
"EP",
"WO",
"HK",
"IL",
"ZA",
"CA",
"KR"
] | null |
actaaaagcaaattctcaggctt | 5561 | EP4416284A1 | Extra-hepatic delivery irna compositions and methods of use thereof | 20,240,821 | 1 | [
"JP",
"NZ",
"EA",
"SG",
"CN",
"MX",
"AU",
"IN",
"US",
"EP",
"WO",
"HK",
"IL",
"ZA",
"CA",
"KR"
] | null |
actaaaagcaaattctcaggctt | 5561 | EP4416284A1 | EXTRAHEPATISCHE IRNA-ZUSAMMENSETZUNGEN ZUR ABGABE UND VERFAHREN ZUR VERWENDUNG DAVON | 20,240,821 | 1 | [
"JP",
"NZ",
"EA",
"SG",
"CN",
"MX",
"AU",
"IN",
"US",
"EP",
"WO",
"HK",
"IL",
"ZA",
"CA",
"KR"
] | null |
actaaaagcaaattctcaggctt | 5561 | EP4416284A1 | COMPOSITIONS D'ARNI À ADMINISTRATION EXTRA-HÉPATIQUE ET LEURS PROCÉDÉS D'UTILISATION | 20,240,821 | 1 | [
"JP",
"NZ",
"EA",
"SG",
"CN",
"MX",
"AU",
"IN",
"US",
"EP",
"WO",
"HK",
"IL",
"ZA",
"CA",
"KR"
] | null |
actaaaagcaaattctcaggctt | 4755 | EP4416284A1 | Extra-hepatic delivery irna compositions and methods of use thereof | 20,240,821 | 1 | [
"JP",
"NZ",
"EA",
"SG",
"CN",
"MX",
"AU",
"IN",
"US",
"EP",
"WO",
"HK",
"IL",
"ZA",
"CA",
"KR"
] | null |
actaaaagcaaattctcaggctt | 4755 | EP4416284A1 | EXTRAHEPATISCHE IRNA-ZUSAMMENSETZUNGEN ZUR ABGABE UND VERFAHREN ZUR VERWENDUNG DAVON | 20,240,821 | 1 | [
"JP",
"NZ",
"EA",
"SG",
"CN",
"MX",
"AU",
"IN",
"US",
"EP",
"WO",
"HK",
"IL",
"ZA",
"CA",
"KR"
] | null |
actaaaagcaaattctcaggctt | 4755 | EP4416284A1 | COMPOSITIONS D'ARNI À ADMINISTRATION EXTRA-HÉPATIQUE ET LEURS PROCÉDÉS D'UTILISATION | 20,240,821 | 1 | [
"JP",
"NZ",
"EA",
"SG",
"CN",
"MX",
"AU",
"IN",
"US",
"EP",
"WO",
"HK",
"IL",
"ZA",
"CA",
"KR"
] | null |
actaaaagcaaattctcaggctt | 5921 | EP4416284A1 | Extra-hepatic delivery irna compositions and methods of use thereof | 20,240,821 | 1 | [
"JP",
"NZ",
"EA",
"SG",
"CN",
"MX",
"AU",
"IN",
"US",
"EP",
"WO",
"HK",
"IL",
"ZA",
"CA",
"KR"
] | [{"norInfos":[{"sourceData":"OTHER","norInfo":[{"modificationType":"Other"}]},{"sourceData":"2'-O-methyladenosine-3'-phosphorothioate","norInfo":[{"modificationType":"Chemical","modification":["Phosphorothioate","2'-O-methyl"]}]}],"locations":["1->1"],"infos":["OTHER","2'-O-methyladenosine-3'-phosphorothioate"]},{"norI... |
actaaaagcaaattctcaggctt | 5921 | EP4416284A1 | EXTRAHEPATISCHE IRNA-ZUSAMMENSETZUNGEN ZUR ABGABE UND VERFAHREN ZUR VERWENDUNG DAVON | 20,240,821 | 1 | [
"JP",
"NZ",
"EA",
"SG",
"CN",
"MX",
"AU",
"IN",
"US",
"EP",
"WO",
"HK",
"IL",
"ZA",
"CA",
"KR"
] | [{"norInfos":[{"sourceData":"OTHER","norInfo":[{"modificationType":"Other"}]},{"sourceData":"2'-O-methyladenosine-3'-phosphorothioate","norInfo":[{"modificationType":"Chemical","modification":["Phosphorothioate","2'-O-methyl"]}]}],"locations":["1->1"],"infos":["OTHER","2'-O-methyladenosine-3'-phosphorothioate"]},{"norI... |
actaaaagcaaattctcaggctt | 5921 | EP4416284A1 | COMPOSITIONS D'ARNI À ADMINISTRATION EXTRA-HÉPATIQUE ET LEURS PROCÉDÉS D'UTILISATION | 20,240,821 | 1 | [
"JP",
"NZ",
"EA",
"SG",
"CN",
"MX",
"AU",
"IN",
"US",
"EP",
"WO",
"HK",
"IL",
"ZA",
"CA",
"KR"
] | [{"norInfos":[{"sourceData":"OTHER","norInfo":[{"modificationType":"Other"}]},{"sourceData":"2'-O-methyladenosine-3'-phosphorothioate","norInfo":[{"modificationType":"Chemical","modification":["Phosphorothioate","2'-O-methyl"]}]}],"locations":["1->1"],"infos":["OTHER","2'-O-methyladenosine-3'-phosphorothioate"]},{"norI... |
actaaaagcaaattctcaggctt | 5115 | EP4416284A1 | Extra-hepatic delivery irna compositions and methods of use thereof | 20,240,821 | 1 | [
"JP",
"NZ",
"EA",
"SG",
"CN",
"MX",
"AU",
"IN",
"US",
"EP",
"WO",
"HK",
"IL",
"ZA",
"CA",
"KR"
] | [{"norInfos":[{"sourceData":"OTHER","norInfo":[{"modificationType":"Other"}]},{"sourceData":"2'-O-methyladenosine-3'-phosphorothioate","norInfo":[{"modificationType":"Chemical","modification":["Phosphorothioate","2'-O-methyl"]}]}],"locations":["1->1"],"infos":["OTHER","2'-O-methyladenosine-3'-phosphorothioate"]},{"norI... |
actaaaagcaaattctcaggctt | 5115 | EP4416284A1 | EXTRAHEPATISCHE IRNA-ZUSAMMENSETZUNGEN ZUR ABGABE UND VERFAHREN ZUR VERWENDUNG DAVON | 20,240,821 | 1 | [
"JP",
"NZ",
"EA",
"SG",
"CN",
"MX",
"AU",
"IN",
"US",
"EP",
"WO",
"HK",
"IL",
"ZA",
"CA",
"KR"
] | [{"norInfos":[{"sourceData":"OTHER","norInfo":[{"modificationType":"Other"}]},{"sourceData":"2'-O-methyladenosine-3'-phosphorothioate","norInfo":[{"modificationType":"Chemical","modification":["Phosphorothioate","2'-O-methyl"]}]}],"locations":["1->1"],"infos":["OTHER","2'-O-methyladenosine-3'-phosphorothioate"]},{"norI... |
actaaaagcaaattctcaggctt | 5115 | EP4416284A1 | COMPOSITIONS D'ARNI À ADMINISTRATION EXTRA-HÉPATIQUE ET LEURS PROCÉDÉS D'UTILISATION | 20,240,821 | 1 | [
"JP",
"NZ",
"EA",
"SG",
"CN",
"MX",
"AU",
"IN",
"US",
"EP",
"WO",
"HK",
"IL",
"ZA",
"CA",
"KR"
] | [{"norInfos":[{"sourceData":"OTHER","norInfo":[{"modificationType":"Other"}]},{"sourceData":"2'-O-methyladenosine-3'-phosphorothioate","norInfo":[{"modificationType":"Chemical","modification":["Phosphorothioate","2'-O-methyl"]}]}],"locations":["1->1"],"infos":["OTHER","2'-O-methyladenosine-3'-phosphorothioate"]},{"norI... |
tttgttctggtcatccaaaggct | 2886 | EP4416284A1 | Extra-hepatic delivery irna compositions and methods of use thereof | 20,240,821 | 1 | [
"JP",
"NZ",
"EA",
"SG",
"CN",
"MX",
"AU",
"IN",
"US",
"EP",
"WO",
"HK",
"IL",
"ZA",
"CA",
"KR"
] | [{"norInfos":[{"sourceData":"OTHER","norInfo":[{"modificationType":"Other"}]},{"sourceData":"2'-O-methyluridine-3'-phosphorothioate 5'-(E)-Vinylphosphonate","norInfo":[{"modificationType":"Non natural base","modification":["um"]},{"modificationType":"Chemical","modification":["Phosphorothioate"]}]}],"locations":["1->1"... |
tttgttctggtcatccaaaggct | 2886 | EP4416284A1 | EXTRAHEPATISCHE IRNA-ZUSAMMENSETZUNGEN ZUR ABGABE UND VERFAHREN ZUR VERWENDUNG DAVON | 20,240,821 | 1 | [
"JP",
"NZ",
"EA",
"SG",
"CN",
"MX",
"AU",
"IN",
"US",
"EP",
"WO",
"HK",
"IL",
"ZA",
"CA",
"KR"
] | [{"norInfos":[{"sourceData":"OTHER","norInfo":[{"modificationType":"Other"}]},{"sourceData":"2'-O-methyluridine-3'-phosphorothioate 5'-(E)-Vinylphosphonate","norInfo":[{"modificationType":"Non natural base","modification":["um"]},{"modificationType":"Chemical","modification":["Phosphorothioate"]}]}],"locations":["1->1"... |
tttgttctggtcatccaaaggct | 2886 | EP4416284A1 | COMPOSITIONS D'ARNI À ADMINISTRATION EXTRA-HÉPATIQUE ET LEURS PROCÉDÉS D'UTILISATION | 20,240,821 | 1 | [
"JP",
"NZ",
"EA",
"SG",
"CN",
"MX",
"AU",
"IN",
"US",
"EP",
"WO",
"HK",
"IL",
"ZA",
"CA",
"KR"
] | [{"norInfos":[{"sourceData":"OTHER","norInfo":[{"modificationType":"Other"}]},{"sourceData":"2'-O-methyluridine-3'-phosphorothioate 5'-(E)-Vinylphosphonate","norInfo":[{"modificationType":"Non natural base","modification":["um"]},{"modificationType":"Chemical","modification":["Phosphorothioate"]}]}],"locations":["1->1"... |
tttgttctggtcatccaaaggct | 1977 | EP4416284A1 | Extra-hepatic delivery irna compositions and methods of use thereof | 20,240,821 | 1 | [
"JP",
"NZ",
"EA",
"SG",
"CN",
"MX",
"AU",
"IN",
"US",
"EP",
"WO",
"HK",
"IL",
"ZA",
"CA",
"KR"
] | null |
tttgttctggtcatccaaaggct | 1977 | EP4416284A1 | EXTRAHEPATISCHE IRNA-ZUSAMMENSETZUNGEN ZUR ABGABE UND VERFAHREN ZUR VERWENDUNG DAVON | 20,240,821 | 1 | [
"JP",
"NZ",
"EA",
"SG",
"CN",
"MX",
"AU",
"IN",
"US",
"EP",
"WO",
"HK",
"IL",
"ZA",
"CA",
"KR"
] | null |
tttgttctggtcatccaaaggct | 1977 | EP4416284A1 | COMPOSITIONS D'ARNI À ADMINISTRATION EXTRA-HÉPATIQUE ET LEURS PROCÉDÉS D'UTILISATION | 20,240,821 | 1 | [
"JP",
"NZ",
"EA",
"SG",
"CN",
"MX",
"AU",
"IN",
"US",
"EP",
"WO",
"HK",
"IL",
"ZA",
"CA",
"KR"
] | null |
tttgttctggtcatccaaaggct | 2245 | EP4416284A1 | Extra-hepatic delivery irna compositions and methods of use thereof | 20,240,821 | 1 | [
"JP",
"NZ",
"EA",
"SG",
"CN",
"MX",
"AU",
"IN",
"US",
"EP",
"WO",
"HK",
"IL",
"ZA",
"CA",
"KR"
] | [{"norInfos":[{"sourceData":"OTHER","norInfo":[{"modificationType":"Other"}]},{"sourceData":"2'-O-methyluridine-3'-phosphorothioate 5'-(E)-Vinylphosphonate","norInfo":[{"modificationType":"Non natural base","modification":["um"]},{"modificationType":"Chemical","modification":["Phosphorothioate"]}]}],"locations":["1->1"... |
tttgttctggtcatccaaaggct | 2245 | EP4416284A1 | EXTRAHEPATISCHE IRNA-ZUSAMMENSETZUNGEN ZUR ABGABE UND VERFAHREN ZUR VERWENDUNG DAVON | 20,240,821 | 1 | [
"JP",
"NZ",
"EA",
"SG",
"CN",
"MX",
"AU",
"IN",
"US",
"EP",
"WO",
"HK",
"IL",
"ZA",
"CA",
"KR"
] | [{"norInfos":[{"sourceData":"OTHER","norInfo":[{"modificationType":"Other"}]},{"sourceData":"2'-O-methyluridine-3'-phosphorothioate 5'-(E)-Vinylphosphonate","norInfo":[{"modificationType":"Non natural base","modification":["um"]},{"modificationType":"Chemical","modification":["Phosphorothioate"]}]}],"locations":["1->1"... |
tttgttctggtcatccaaaggct | 2245 | EP4416284A1 | COMPOSITIONS D'ARNI À ADMINISTRATION EXTRA-HÉPATIQUE ET LEURS PROCÉDÉS D'UTILISATION | 20,240,821 | 1 | [
"JP",
"NZ",
"EA",
"SG",
"CN",
"MX",
"AU",
"IN",
"US",
"EP",
"WO",
"HK",
"IL",
"ZA",
"CA",
"KR"
] | [{"norInfos":[{"sourceData":"OTHER","norInfo":[{"modificationType":"Other"}]},{"sourceData":"2'-O-methyluridine-3'-phosphorothioate 5'-(E)-Vinylphosphonate","norInfo":[{"modificationType":"Non natural base","modification":["um"]},{"modificationType":"Chemical","modification":["Phosphorothioate"]}]}],"locations":["1->1"... |
tttgttctggtcatccaaaggct | 2620 | EP4416284A1 | Extra-hepatic delivery irna compositions and methods of use thereof | 20,240,821 | 1 | [
"JP",
"NZ",
"EA",
"SG",
"CN",
"MX",
"AU",
"IN",
"US",
"EP",
"WO",
"HK",
"IL",
"ZA",
"CA",
"KR"
] | null |
tttgttctggtcatccaaaggct | 2620 | EP4416284A1 | EXTRAHEPATISCHE IRNA-ZUSAMMENSETZUNGEN ZUR ABGABE UND VERFAHREN ZUR VERWENDUNG DAVON | 20,240,821 | 1 | [
"JP",
"NZ",
"EA",
"SG",
"CN",
"MX",
"AU",
"IN",
"US",
"EP",
"WO",
"HK",
"IL",
"ZA",
"CA",
"KR"
] | null |
tttgttctggtcatccaaaggct | 2620 | EP4416284A1 | COMPOSITIONS D'ARNI À ADMINISTRATION EXTRA-HÉPATIQUE ET LEURS PROCÉDÉS D'UTILISATION | 20,240,821 | 1 | [
"JP",
"NZ",
"EA",
"SG",
"CN",
"MX",
"AU",
"IN",
"US",
"EP",
"WO",
"HK",
"IL",
"ZA",
"CA",
"KR"
] | null |
gacccgttctctacaattt | 101 | JP2024535850A | 補体成分(C3)をサイレンシングするためのiRNA組成物および方法 | 20,241,002 | 2 | [
"JP",
"US",
"WO",
"EP"
] | [{"norInfos":[{"sourceData":"OTHER","norInfo":[{"modificationType":"Other"}]},{"sourceData":"2'-O-methylguanosine-3'-phosphorothioate","norInfo":[{"modificationType":"Non natural base","modification":["gm"]},{"modificationType":"Chemical","modification":["Phosphorothioate","2'-O-methyl"]}]}],"locations":["1->1"],"infos... |
gacccgttctctacaattt | 11 | JP2024535850A | 補体成分(C3)をサイレンシングするためのiRNA組成物および方法 | 20,241,002 | 2 | [
"JP",
"US",
"WO",
"EP"
] | null |
ccctactgcagctaaaagacttt | 886 | JP2024535850A | 補体成分(C3)をサイレンシングするためのiRNA組成物および方法 | 20,241,002 | 2 | [
"JP",
"US",
"WO",
"EP"
] | null |
ccctactgcagctaaaagacttt | 833 | JP2024535850A | 補体成分(C3)をサイレンシングするためのiRNA組成物および方法 | 20,241,002 | 2 | [
"JP",
"US",
"WO",
"EP"
] | null |
ccatcgcctcgtccgtagtctcc | 997 | EP4416284A1 | Extra-hepatic delivery irna compositions and methods of use thereof | 20,240,821 | 1 | [
"JP",
"NZ",
"EA",
"SG",
"CN",
"MX",
"AU",
"IN",
"US",
"EP",
"WO",
"HK",
"IL",
"ZA",
"CA",
"KR"
] | null |
ccatcgcctcgtccgtagtctcc | 997 | EP4416284A1 | EXTRAHEPATISCHE IRNA-ZUSAMMENSETZUNGEN ZUR ABGABE UND VERFAHREN ZUR VERWENDUNG DAVON | 20,240,821 | 1 | [
"JP",
"NZ",
"EA",
"SG",
"CN",
"MX",
"AU",
"IN",
"US",
"EP",
"WO",
"HK",
"IL",
"ZA",
"CA",
"KR"
] | null |
ccatcgcctcgtccgtagtctcc | 997 | EP4416284A1 | COMPOSITIONS D'ARNI À ADMINISTRATION EXTRA-HÉPATIQUE ET LEURS PROCÉDÉS D'UTILISATION | 20,240,821 | 1 | [
"JP",
"NZ",
"EA",
"SG",
"CN",
"MX",
"AU",
"IN",
"US",
"EP",
"WO",
"HK",
"IL",
"ZA",
"CA",
"KR"
] | null |
aauggaaccuaguaauagguu | 320 | US11208660B1 | Coronavirus iRNA compositions and methods of use thereof | 20,211,228 | 3 | [
"HK",
"US",
"JP",
"CN",
"TW",
"WO",
"EP"
] | null |
uaacacggacgaaaccguaagca | 1260 | US11208660B1 | Coronavirus iRNA compositions and methods of use thereof | 20,211,228 | 3 | [
"HK",
"US",
"JP",
"CN",
"TW",
"WO",
"EP"
] | null |
ucgaaggugugacuuccaugcca | 1238 | US11208660B1 | Coronavirus iRNA compositions and methods of use thereof | 20,211,228 | 3 | [
"HK",
"US",
"JP",
"CN",
"TW",
"WO",
"EP"
] | null |
uaagaagagcaagaagaagauug | 1273 | US11208660B1 | Coronavirus iRNA compositions and methods of use thereof | 20,211,228 | 3 | [
"HK",
"US",
"JP",
"CN",
"TW",
"WO",
"EP"
] | null |
ugcaaagaauagagcucgcaa | 784 | US11208660B1 | Coronavirus iRNA compositions and methods of use thereof | 20,211,228 | 3 | [
"HK",
"US",
"JP",
"CN",
"TW",
"WO",
"EP"
] | null |
ggcacgcuaguagucgucgucgg | 643 | US11208660B1 | Coronavirus iRNA compositions and methods of use thereof | 20,211,228 | 3 | [
"HK",
"US",
"JP",
"CN",
"TW",
"WO",
"EP"
] | null |
uucgugguauucuugcuaguu | 133 | US11208660B1 | Coronavirus iRNA compositions and methods of use thereof | 20,211,228 | 3 | [
"HK",
"US",
"JP",
"CN",
"TW",
"WO",
"EP"
] | null |
uaaacgaaugaguacauaaguuc | 1358 | US11208660B1 | Coronavirus iRNA compositions and methods of use thereof | 20,211,228 | 3 | [
"HK",
"US",
"JP",
"CN",
"TW",
"WO",
"EP"
] | null |
ccuaauguguaaaauuaauuu | 370 | US11208660B1 | Coronavirus iRNA compositions and methods of use thereof | 20,211,228 | 3 | [
"HK",
"US",
"JP",
"CN",
"TW",
"WO",
"EP"
] | null |
caagacgcaguauuauuggguaa | 700 | US11208660B1 | Coronavirus iRNA compositions and methods of use thereof | 20,211,228 | 3 | [
"HK",
"US",
"JP",
"CN",
"TW",
"WO",
"EP"
] | null |
auaauaaagucuagccuuacccc | 593 | US11208660B1 | Coronavirus iRNA compositions and methods of use thereof | 20,211,228 | 3 | [
"HK",
"US",
"JP",
"CN",
"TW",
"WO",
"EP"
] | null |
aucuucuucuugcucuucuua | 918 | US11208660B1 | Coronavirus iRNA compositions and methods of use thereof | 20,211,228 | 3 | [
"HK",
"US",
"JP",
"CN",
"TW",
"WO",
"EP"
] | null |
ucaguauuauuggguaaaccuug | 1409 | US11208660B1 | Coronavirus iRNA compositions and methods of use thereof | 20,211,228 | 3 | [
"HK",
"US",
"JP",
"CN",
"TW",
"WO",
"EP"
] | null |
uaagaaagcguucgugauguagc | 1389 | US11208660B1 | Coronavirus iRNA compositions and methods of use thereof | 20,211,228 | 3 | [
"HK",
"US",
"JP",
"CN",
"TW",
"WO",
"EP"
] | null |
uaagaaagcguucgugauguagc | 679 | US11208660B1 | Coronavirus iRNA compositions and methods of use thereof | 20,211,228 | 3 | [
"HK",
"US",
"JP",
"CN",
"TW",
"WO",
"EP"
] | null |
aggcacuaguacugaugucgu | 225 | US11208660B1 | Coronavirus iRNA compositions and methods of use thereof | 20,211,228 | 3 | [
"HK",
"US",
"JP",
"CN",
"TW",
"WO",
"EP"
] | null |
uagccuuucugcuauuccuug | 334 | US11208660B1 | Coronavirus iRNA compositions and methods of use thereof | 20,211,228 | 3 | [
"HK",
"US",
"JP",
"CN",
"TW",
"WO",
"EP"
] | null |
caaagaauagagcucgcacca | 786 | US11208660B1 | Coronavirus iRNA compositions and methods of use thereof | 20,211,228 | 3 | [
"HK",
"US",
"JP",
"CN",
"TW",
"WO",
"EP"
] | null |
cuguaugguaggauuuuccacua | 397 | US11208660B1 | Coronavirus iRNA compositions and methods of use thereof | 20,211,228 | 3 | [
"HK",
"US",
"JP",
"CN",
"TW",
"WO",
"EP"
] | null |
uauagccucauaaaacucagguu | 1159 | US11208660B1 | Coronavirus iRNA compositions and methods of use thereof | 20,211,228 | 3 | [
"HK",
"US",
"JP",
"CN",
"TW",
"WO",
"EP"
] | null |
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