prompt string | hit int64 | screen_id int64 | crispr_strategy string | gene string | phenotype string | cell_type string | gene_context string |
|---|---|---|---|---|---|---|---|
Does Knockout of NUP98 in Pre-B Acute Lymphoblastic Leukemia Cell Line causally result in cell proliferation? | 0 | 1,996 | Knockout | NUP98 | cell proliferation | Pre-B Acute Lymphoblastic Leukemia Cell Line | Gene: NUP98 (nucleoporin 98 and 96 precursor)
Type: protein-coding
Summary: Nuclear pore complexes (NPCs) regulate the transport of macromolecules between the nucleus and cytoplasm, and are composed of many polypeptide subunits, many of which belong to the nucleoporin family. This gene belongs to the nu... |
Does Knockout of SMAD4 in Chronic Myeloid Leukemia Cell Line causally result in cell proliferation? | 1 | 1,032 | Knockout | SMAD4 | cell proliferation | Chronic Myeloid Leukemia Cell Line | Gene: SMAD4 (SMAD family member 4)
Type: protein-coding
Summary: This gene encodes a member of the Smad family of signal transduction proteins. Smad proteins are phosphorylated and activated by transmembrane serine-threonine receptor kinases in response to transforming growth factor (TGF)-beta signaling... |
Does Knockout of PSMD1 in Esophageal Squamous Cell Carcinoma Cell Line causally result in cell proliferation? | 1 | 334 | Knockout | PSMD1 | cell proliferation | Esophageal Squamous Cell Carcinoma Cell Line | Gene: PSMD1 (proteasome 26S subunit, non-ATPase 1)
Type: protein-coding
Summary: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings ar... |
Does Knockout of PRIMPOL in Glioblastoma Cell Line causally result in cell proliferation? | 0 | 519 | Knockout | PRIMPOL | cell proliferation | Glioblastoma Cell Line | Gene: PRIMPOL (primase and DNA directed polymerase)
Type: protein-coding
Summary: This gene encodes a DNA primase-polymerase that belongs to a superfamily of archaeao-eukaryotic primases. Members of this family have primase activity, catalyzing the synthesis of short RNA primers that serve as starting p... |
Does Knockout of SLC4A11 in Chronic Myeloid Leukemia Cell Line causally result in cell proliferation? | 0 | 1,789 | Knockout | SLC4A11 | cell proliferation | Chronic Myeloid Leukemia Cell Line | Gene: SLC4A11 (solute carrier family 4 member 11)
Type: protein-coding
Summary: This gene encodes a voltage-regulated, electrogenic sodium-coupled borate cotransporter that is essential for borate homeostasis, cell growth and cell proliferation. Mutations in this gene have been associated with a number ... |
Does Knockout of YIF1A in Ewing's Sarcoma Cell Line causally result in cell proliferation? | 0 | 763 | Knockout | YIF1A | cell proliferation | Ewing's Sarcoma Cell Line | Gene: YIF1A (Yip1 interacting factor homolog A, membrane trafficking protein)
Type: protein-coding
Summary: Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport. Located in Golgi apparatus and endoplasmic reticulum-Golgi intermediate compartment. [provided by Alliance of... |
Does Knockout of RFX2 in Mammary Gland Tumor Cell Line causally result in cell proliferation? | 0 | 220 | Knockout | RFX2 | cell proliferation | Mammary Gland Tumor Cell Line | Gene: RFX2 (regulatory factor X2)
Type: protein-coding
Summary: This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factor... |
Does Knockout of POLR2H in Renal Cancer Cell Line causally result in cell proliferation? | 1 | 319 | Knockout | POLR2H | cell proliferation | Renal Cancer Cell Line | Gene: POLR2H (RNA polymerase II, I and III subunit H)
Type: protein-coding
Summary: The three eukaryotic RNA polymerases are complex multisubunit enzymes that play a central role in the transcription of nuclear genes. This gene encodes an essential and highly conserved subunit of RNA polymerase II that ... |
Does Knockout of PMAIP1 in Cancer Cell Line causally result in cell proliferation? | 0 | 1,308 | Knockout | PMAIP1 | cell proliferation | Cancer Cell Line | Gene: PMAIP1 (phorbol-12-myristate-13-acetate-induced protein 1)
Type: protein-coding
Summary: This gene belongs to a pro-apoptotic subfamily within the BCL-2 protein family, referred to as the BCL-2 homology domain 3 (BH3)-only subfamily, which determine whether a cell commits to apoptosis. In response... |
Does Knockout of MTG2 in Oral Squamous Cell Carcinoma Cell Line causally result in cell proliferation? | 1 | 1,311 | Knockout | MTG2 | cell proliferation | Oral Squamous Cell Carcinoma Cell Line | Gene: MTG2 (mitochondrial ribosome associated GTPase 2)
Type: protein-coding
Summary: Small G proteins, such as GTPBP5, act as molecular switches that play crucial roles in the regulation of fundamental cellular processes such as protein synthesis, nuclear transport, membrane trafficking, and signal tra... |
Does Knockout of SLC30A7 in T-lymphoma cell line causally result in cell proliferation? | 0 | 478 | Knockout | SLC30A7 | cell proliferation | T-lymphoma cell line | Gene: SLC30A7 (solute carrier family 30 member 7)
Type: protein-coding
Summary: Zinc functions as a cofactor for numerous enzymes, nuclear factors, and hormones and as an intra- and intercellular signal ion. Members of the zinc transporter (ZNT)/SLC30 subfamily of the cation diffusion facilitator family... |
Does Knockout of CARM1 in Chronic Myelogenous Leukemia Cell Line causally result in response to chemicals? | 0 | 2,383 | Knockout | CARM1 | response to chemicals | Chronic Myelogenous Leukemia Cell Line | Gene: CARM1 (coactivator associated arginine methyltransferase 1)
Type: protein-coding
Summary: This gene belongs to the protein arginine methyltransferase (PRMT) family. The encoded enzyme catalyzes the methylation of guanidino nitrogens of arginyl residues of proteins. The enzyme acts specifically on ... |
Does Knockout of OR13C5 in Diffuse Large B-cell Lymphoma Cell causally result in response to chemicals? | 1 | 2,222 | Knockout | OR13C5 | response to chemicals | Diffuse Large B-cell Lymphoma Cell | Gene: OR13C5 (olfactory receptor family 13 subfamily C member 5)
Type: protein-coding
Summary: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-prot... |
Does Knockout of TRIP6 in Prostate Cancer Cell Line causally result in cell proliferation? | 0 | 843 | Knockout | TRIP6 | cell proliferation | Prostate Cancer Cell Line | Gene: TRIP6 (thyroid hormone receptor interactor 6)
Type: protein-coding
Summary: This gene is a member of the zyxin family and encodes a protein with three LIM zinc-binding domains. This protein localizes to focal adhesion sites and along actin stress fibers. Recruitment of this protein to the plasma m... |
Does Knockout of PRIM1 in Monocytic Leukemia Cell Line causally result in cell proliferation? | 1 | 80 | Knockout | PRIM1 | cell proliferation | Monocytic Leukemia Cell Line | Gene: PRIM1 (DNA primase subunit 1)
Type: protein-coding
Summary: The replication of DNA in eukaryotic cells is carried out by a complex chromosomal replication apparatus, in which DNA polymerase alpha and primase are two key enzymatic components. Primase, which is a heterodimer of a small subunit and a... |
Does Knockout of TICRR in Colonic Cancer Cell Line causally result in cell proliferation? | 1 | 815 | Knockout | TICRR | cell proliferation | Colonic Cancer Cell Line | Gene: TICRR (TOPBP1 interacting checkpoint and replication regulator)
Type: protein-coding
Summary: Treslin is involved in the initiation of DNA replication (Kumagai et al., 2010 [PubMed 20116089]).[supplied by OMIM, Apr 2010]
Gene Ontology: BP: DNA damage response, DNA repair, DNA replication,... |
Does Knockout of PRSS54 in Lung Squamous Cell Carcinoma Cell Line causally result in cell proliferation? | 0 | 839 | Knockout | PRSS54 | cell proliferation | Lung Squamous Cell Carcinoma Cell Line | Gene: PRSS54 (serine protease 54)
Type: protein-coding
Summary: This gene encodes a putative serine-type endopeptidase containing the peptidase S1 domain. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2015].
Gene Ontology: BP: proteolysis; M... |
Does Knockout of ARCN1 in Mammary Gland Tumor Cell Line causally result in cell proliferation? | 1 | 220 | Knockout | ARCN1 | cell proliferation | Mammary Gland Tumor Cell Line | Gene: ARCN1 (archain 1 coat protein complex I subunit delta)
Type: protein-coding
Summary: This gene maps in a region, which include the mixed lineage leukemia and Friend leukemia virus integration 1 genes, where multiple disease-associated chromosome translocations occur. It is an intracellular protein... |
Does Knockout of MYC in Ewing's Sarcoma Cell Line causally result in cell proliferation? | 1 | 763 | Knockout | MYC | cell proliferation | Ewing's Sarcoma Cell Line | Gene: MYC (MYC proto-oncogene, bHLH transcription factor)
Type: protein-coding
Summary: This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcri... |
Does Knockout of TSPAN6 in Lung Adenocarcinoma Cell Line causally result in cell proliferation? | 0 | 897 | Knockout | TSPAN6 | cell proliferation | Lung Adenocarcinoma Cell Line | Gene: TSPAN6 (tetraspanin 6)
Type: protein-coding
Summary: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The protei... |
Does Knockout of PRPF6 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in cell proliferation? | 1 | 427 | Knockout | PRPF6 | cell proliferation | Pancreatic Ductal Adenocarcinoma Cell Line | Gene: PRPF6 (pre-mRNA processing factor 6)
Type: protein-coding
Summary: The protein encoded by this gene appears to be involved in pre-mRNA splicing, possibly acting as a bridging factor between U5 and U4/U6 snRNPs in formation of the spliceosome. The encoded protein also can bind androgen receptor, pr... |
Does Knockout of GTF2E2 in Prostate Cancer Cell Line causally result in cell proliferation? | 1 | 843 | Knockout | GTF2E2 | cell proliferation | Prostate Cancer Cell Line | Gene: GTF2E2 (general transcription factor IIE subunit 2)
Type: protein-coding
Summary: The general transcription factor IIE (TFIIE) is part of the RNA polymerase II transcription initiation complex, recruiting TFIIH and being essential for promoter clearance by RNA polymerase II. TFIIE is a heterodimer... |
Does Knockout of BHMT2 in Mammary Gland Tumor Cell Line causally result in cell proliferation? | 1 | 220 | Knockout | BHMT2 | cell proliferation | Mammary Gland Tumor Cell Line | Gene: BHMT2 (betaine--homocysteine S-methyltransferase 2)
Type: protein-coding
Summary: Homocysteine is a sulfur-containing amino acid that plays a crucial role in methylation reactions. Transfer of the methyl group from betaine to homocysteine creates methionine, which donates the methyl group to methy... |
Does Knockout of GEMIN8 in Chronic Myeloid Leukemia Cell Line causally result in cell proliferation? | 0 | 1,789 | Knockout | GEMIN8 | cell proliferation | Chronic Myeloid Leukemia Cell Line | Gene: GEMIN8 (gem nuclear organelle associated protein 8)
Type: protein-coding
Summary: The protein encoded by this gene is part of the SMN complex, which is necessary for spliceosomal snRNP assembly in the cytoplasm and pre-mRNA splicing in the nucleus. The encoded protein binds to both SMN1 and the GE... |
Does Knockout of MAP2K4 in Hepatoma Cell Line causally result in response to virus? | 1 | 2,437 | Knockout | MAP2K4 | response to virus | Hepatoma Cell Line | Gene: MAP2K4 (mitogen-activated protein kinase kinase 4)
Type: protein-coding
Summary: This gene encodes a member of the mitogen-activated protein kinase (MAPK) family. Members of this family act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular proc... |
Does Knockout of DMRTA2 in Melanoma Cell Line causally result in cell proliferation? | 1 | 527 | Knockout | DMRTA2 | cell proliferation | Melanoma Cell Line | Gene: DMRTA2 (DMRT like family A2)
Type: protein-coding
Summary: Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II and sex differentiation. Predicted to act upstream of or within nervous system development and ske... |
Does Knockout of ACO1 in Primary Effusion Lymphoma Cell Line causally result in response to chemicals? | 0 | 1,061 | Knockout | ACO1 | response to chemicals | Primary Effusion Lymphoma Cell Line | Gene: ACO1 (aconitase 1)
Type: protein-coding
Summary: The protein encoded by this gene is a bifunctional, cytosolic protein that functions as an essential enzyme in the TCA cycle and interacts with mRNA to control the levels of iron inside cells. When cellular iron levels are high, this protein binds t... |
Does Knockout of ABT1 in Lung Adenocarcinoma Cell Line causally result in cell proliferation? | 1 | 387 | Knockout | ABT1 | cell proliferation | Lung Adenocarcinoma Cell Line | Gene: ABT1 (activator of basal transcription 1)
Type: protein-coding
Summary: Basal transcription of genes by RNA polymerase II requires the interaction of TATA-binding protein (TBP) with the core region of class II promoters. Studies in mouse suggest that the protein encoded by this gene likely activa... |
Does Knockout of SMIM10L1 in Hepatoma Cell Line causally result in cell proliferation? | 0 | 1,206 | Knockout | SMIM10L1 | cell proliferation | Hepatoma Cell Line | Gene: SMIM10L1 (small integral membrane protein 10 like 1)
Type: protein-coding
Summary: Located in mitochondrion. [provided by Alliance of Genome Resources, Jul 2025]
Gene Ontology:
Pathways:
UniProt: P0DMW3
Entrez ID: 100129361 |
Does Knockout of GRK5 in Bladder Carcinoma causally result in cell proliferation? | 0 | 489 | Knockout | GRK5 | cell proliferation | Bladder Carcinoma | Gene: GRK5 (G protein-coupled receptor kinase 5)
Type: protein-coding
Summary: This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled rece... |
Does Knockout of DDX11 in Bladder Carcinoma causally result in cell proliferation? | 1 | 489 | Knockout | DDX11 | cell proliferation | Bladder Carcinoma | Gene: DDX11 (DEAD/H-box helicase 11)
Type: protein-coding
Summary: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiat... |
Does Knockout of DDOST in Lung Cancer Cell Line causally result in response to virus? | 0 | 1,433 | Knockout | DDOST | response to virus | Lung Cancer Cell Line | Gene: DDOST (dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit)
Type: protein-coding
Summary: This gene encodes a component of the oligosaccharyltransferase complex which catalyzes the transfer of high-mannose oligosaccharides to asparagine residues on nascent polypept... |
Does Knockout of POLR1B in Hepatoma Cell Line causally result in response to virus? | 1 | 2,437 | Knockout | POLR1B | response to virus | Hepatoma Cell Line | Gene: POLR1B (RNA polymerase I subunit B)
Type: protein-coding
Summary: Eukaryotic RNA polymerase I (pol I) is responsible for the transcription of ribosomal RNA (rRNA) genes and production of rRNA, the primary component of ribosomes. Pol I is a multisubunit enzyme composed of 6 to 14 polypeptides, depe... |
Does Knockout of TUBAL3 in Endometrial Cancer Cell Line causally result in cell proliferation? | 0 | 758 | Knockout | TUBAL3 | cell proliferation | Endometrial Cancer Cell Line | Gene: TUBAL3 (tubulin alpha like 3)
Type: protein-coding
Summary: Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in microtubule cytoskeleton organization and mitotic cell cycle. Predicted to be active in cytoplasm and microtub... |
Does Knockout of CEP89 in Astrocytoma Cell Line causally result in cell proliferation? | 0 | 904 | Knockout | CEP89 | cell proliferation | Astrocytoma Cell Line | Gene: CEP89 (centrosomal protein 89)
Type: protein-coding
Summary: Involved in non-motile cilium assembly. Acts upstream of or within cilium assembly. Located in several cellular components, including cytosol; microtubule cytoskeleton; and non-motile cilium. Part of ciliary transition fiber. [provided b... |
Does Knockout of DSC2 in Monocytic Leukemia Cell Line causally result in cell proliferation? | 0 | 80 | Knockout | DSC2 | cell proliferation | Monocytic Leukemia Cell Line | Gene: DSC2 (desmocollin 2)
Type: protein-coding
Summary: This gene encodes a member of the desmocollin protein subfamily. Desmocollins, along with desmogleins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist sh... |
Does Knockout of ITGA6 in Gastric Cancer Cell Line causally result in cell proliferation? | 0 | 230 | Knockout | ITGA6 | cell proliferation | Gastric Cancer Cell Line | Gene: ITGA6 (integrin subunit alpha 6)
Type: protein-coding
Summary: The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The enco... |
Does Knockout of CDT1 in Cancer Cell Line causally result in cell proliferation? | 1 | 193 | Knockout | CDT1 | cell proliferation | Cancer Cell Line | Gene: CDT1 (chromatin licensing and DNA replication factor 1)
Type: protein-coding
Summary: The protein encoded by this gene is involved in the formation of the pre-replication complex that is necessary for DNA replication. The encoded protein can bind geminin, which prevents replication and may functio... |
Does Knockout of ANAPC4 in Cancer Cell Line causally result in cell proliferation? | 1 | 948 | Knockout | ANAPC4 | cell proliferation | Cancer Cell Line | Gene: ANAPC4 (anaphase promoting complex subunit 4)
Type: protein-coding
Summary: A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which... |
Does Knockout of PAX6 in Colonic Adenocarcinoma Cell Line causally result in response to chemicals? | 0 | 1,736 | Knockout | PAX6 | response to chemicals | Colonic Adenocarcinoma Cell Line | Gene: PAX6 (paired box 6)
Type: protein-coding
Summary: This gene encodes paired box protein Pax-6, one of many human homologs of the Drosophila melanogaster gene prd. In addition to a conserved paired box domain, a hallmark feature of this gene family, the encoded protein also contains a homeobox domai... |
Does Knockout of MRPL4 in Mammary Gland Tumor Cell Line causally result in cell proliferation? | 1 | 220 | Knockout | MRPL4 | cell proliferation | Mammary Gland Tumor Cell Line | Gene: MRPL4 (mitochondrial ribosomal protein L4)
Type: protein-coding
Summary: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. T... |
Does Knockout of HSD17B11 in Monocytic Leukemia Cell Line causally result in RNA accumulation? | 0 | 1,968 | Knockout | HSD17B11 | RNA accumulation | Monocytic Leukemia Cell Line | Gene: HSD17B11 (hydroxysteroid 17-beta dehydrogenase 11)
Type: protein-coding
Summary: Short-chain alcohol dehydrogenases, such as HSD17B11, metabolize secondary alcohols and ketones (Brereton et al., 2001 [PubMed 11165019]).[supplied by OMIM, Jun 2009].
Gene Ontology: BP: androgen catabolic pr... |
Does Knockout of TNFSF14 in Cancer Cell Line causally result in cell proliferation? | 0 | 948 | Knockout | TNFSF14 | cell proliferation | Cancer Cell Line | Gene: TNFSF14 (TNF superfamily member 14)
Type: protein-coding
Summary: The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF14, which is a member of the tumor necrosis factor receptor superfamily, and which is also known as a ... |
Does Knockout of EVPL in Chronic Myeloid Leukemia Cell Line causally result in response to chemicals? | 0 | 1,397 | Knockout | EVPL | response to chemicals | Chronic Myeloid Leukemia Cell Line | Gene: EVPL (envoplakin)
Type: protein-coding
Summary: This gene encodes a member of the plakin family of proteins that forms a component of desmosomes and the epidermal cornified envelope. This gene is located in the tylosis oesophageal cancer locus on chromosome 17q25, and its deletion is associated wi... |
Does Knockout of PRKCSH in Chronic Myeloid Leukemia Cell Line causally result in cell proliferation? | 0 | 1,032 | Knockout | PRKCSH | cell proliferation | Chronic Myeloid Leukemia Cell Line | Gene: PRKCSH (PRKCSH beta subunit of glucosidase II)
Type: protein-coding
Summary: This gene encodes the beta-subunit of glucosidase II, an N-linked glycan-processing enzyme in the endoplasmic reticulum. The encoded protein is an acidic phosphoprotein known to be a substrate for protein kinase C. Mutati... |
Does Knockout of TM4SF4 in Lymphoma or Leukaemia Cell Line causally result in protein/peptide accumulation? | 0 | 1,218 | Knockout | TM4SF4 | protein/peptide accumulation | Lymphoma or Leukaemia Cell Line | Gene: TM4SF4 (transmembrane 4 L six family member 4)
Type: protein-coding
Summary: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydroph... |
Does Knockout of TFAP4 in Non-Small Cell Lung Cancer Cell Line causally result in cell proliferation? | 1 | 1,246 | Knockout | TFAP4 | cell proliferation | Non-Small Cell Lung Cancer Cell Line | Gene: TFAP4 (transcription factor AP-4)
Type: protein-coding
Summary: Transcription factors of the basic helix-loop-helix-zipper (bHLH-ZIP) family contain a basic domain, which is used for DNA binding, and HLH and ZIP domains, which are used for oligomerization. Transcription factor AP4 activates both v... |
Does Knockout of RIOK2 in Oral Squamous Cell Carcinoma Cell Line causally result in cell proliferation? | 1 | 1,311 | Knockout | RIOK2 | cell proliferation | Oral Squamous Cell Carcinoma Cell Line | Gene: RIOK2 (RIO kinase 2)
Type: protein-coding
Summary: Predicted to enable protein kinase activity. Involved in several processes, including positive regulation of rRNA processing; positive regulation of ribosomal small subunit export from nucleus; and regulation of mitotic metaphase/anaphase transiti... |
Does Knockout of FH in Cervical Adenocarcinoma Cell Line causally result in protein/peptide accumulation? | 0 | 2,404 | Knockout | FH | protein/peptide accumulation | Cervical Adenocarcinoma Cell Line | Gene: FH (fumarate hydratase)
Type: protein-coding
Summary: The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differi... |
Does Knockout of NPIPB6 in Monocytic Leukemia Cell Line causally result in cell proliferation? | 1 | 80 | Knockout | NPIPB6 | cell proliferation | Monocytic Leukemia Cell Line | Gene: NPIPB6 (nuclear pore complex interacting protein family member B6)
Type: protein-coding
Summary: Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology:
Pathways:
UniProt: E9PJ23
Entrez ID: 728741 |
Does Knockout of OR5A2 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation? | 0 | 1,658 | Knockout | OR5A2 | cell proliferation | Colonic Adenocarcinoma Cell Line | Gene: OR5A2 (olfactory receptor family 5 subfamily A member 2)
Type: protein-coding
Summary: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protei... |
Does Knockout of DDX51 in Renal Cancer Cell Line causally result in cell proliferation? | 1 | 319 | Knockout | DDX51 | cell proliferation | Renal Cancer Cell Line | Gene: DDX51 (DEAD-box helicase 51)
Type: protein-coding
Summary: Enables RNA binding activity. Predicted to be involved in rRNA processing. Located in membrane. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: BP: rRNA processing, ribosome biogenesis; MF: ATP binding, ATP hyd... |
Does Knockout of IL31 in Primary Effusion Lymphoma Cell Line causally result in cell proliferation? | 0 | 2,119 | Knockout | IL31 | cell proliferation | Primary Effusion Lymphoma Cell Line | Gene: IL31 (interleukin 31)
Type: protein-coding
Summary: IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be inv... |
Does Knockout of KLHL13 in Hepatoma Cell Line causally result in response to virus? | 0 | 2,437 | Knockout | KLHL13 | response to virus | Hepatoma Cell Line | Gene: KLHL13 (kelch like family member 13)
Type: protein-coding
Summary: This gene encodes a BTB and kelch domain containing protein and belongs to the kelch repeat domain containing superfamily of proteins. The encoded protein functions as an adaptor protein that complexes with Cullin 3 and other prote... |
Does Knockout of TNNI2 in Neuroblastoma Cell Line causally result in cell proliferation? | 0 | 824 | Knockout | TNNI2 | cell proliferation | Neuroblastoma Cell Line | Gene: TNNI2 (troponin I2, fast skeletal type)
Type: protein-coding
Summary: This gene encodes a fast-twitch skeletal muscle protein, a member of the troponin I gene family, and a component of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, along with ... |
Does Knockout of ARID3B in Colonic Adenocarcinoma Cell Line causally result in cell proliferation? | 1 | 1,658 | Knockout | ARID3B | cell proliferation | Colonic Adenocarcinoma Cell Line | Gene: ARID3B (AT-rich interaction domain 3B)
Type: protein-coding
Summary: This gene encodes a member of the ARID (AT-rich interaction domain) family of DNA-binding proteins. The encoded protein is homologous with two proteins that bind to the retinoblastoma gene product, and also with the mouse Bright ... |
Does Knockout of PLEKHF1 in Hepatoma Cell Line causally result in response to virus? | 0 | 2,437 | Knockout | PLEKHF1 | response to virus | Hepatoma Cell Line | Gene: PLEKHF1 (pleckstrin homology and FYVE domain containing 1)
Type: protein-coding
Summary: Enables phosphatidylinositol-3-phosphate binding activity; phosphatidylinositol-4-phosphate binding activity; and phosphatidylinositol-5-phosphate binding activity. Involved in endosome organization; positive ... |
Does Knockout of CD70 in Ovarian Cancer Cell Line causally result in cell proliferation? | 0 | 699 | Knockout | CD70 | cell proliferation | Ovarian Cancer Cell Line | Gene: CD70 (CD70 molecule)
Type: protein-coding
Summary: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces pr... |
Does Knockout of CABS1 in Hepatoma Cell Line causally result in response to virus? | 0 | 2,447 | Knockout | CABS1 | response to virus | Hepatoma Cell Line | Gene: CABS1 (calcium binding protein, spermatid associated 1)
Type: protein-coding
Summary: Predicted to enable calcium ion binding activity. Predicted to be involved in flagellated sperm motility and spermatogenesis. Predicted to be located in acrosomal vesicle and sperm principal piece. Predicted to b... |
Does Knockout of ZNF835 in Colonic Adenocarcinoma Cell Line causally result in response to chemicals? | 0 | 1,736 | Knockout | ZNF835 | response to chemicals | Colonic Adenocarcinoma Cell Line | Gene: ZNF835 (zinc finger protein 835)
Type: protein-coding
Summary: Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted t... |
Does Knockout of OR2W3 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation? | 1 | 1,658 | Knockout | OR2W3 | cell proliferation | Colonic Adenocarcinoma Cell Line | Gene: OR2W3 (olfactory receptor family 2 subfamily W member 3)
Type: protein-coding
Summary: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protei... |
Does Knockout of ZNF484 in Prostate Cancer Cell Line causally result in cell proliferation? | 1 | 843 | Knockout | ZNF484 | cell proliferation | Prostate Cancer Cell Line | Gene: ZNF484 (zinc finger protein 484)
Type: protein-coding
Summary: Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by... |
Does Knockout of PRDX5 in Huh-7 Cell causally result in response to virus? | 0 | 1,382 | Knockout | PRDX5 | response to virus | Huh-7 Cell | Gene: PRDX5 (peroxiredoxin 5)
Type: protein-coding
Summary: This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein interacts with peroxisome receptor 1 and plays an antioxidant protective role in differe... |
Does Knockout of FOXD4L6 in Monocytic Leukemia Cell Line causally result in cell proliferation? | 0 | 69 | Knockout | FOXD4L6 | cell proliferation | Monocytic Leukemia Cell Line | Gene: FOXD4L6 (forkhead box D4 like 6)
Type: protein-coding
Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in anatomical structure morphogenesi... |
Does Knockout of RNF139 in Cancer Cell Line causally result in cell proliferation? | 0 | 1,308 | Knockout | RNF139 | cell proliferation | Cancer Cell Line | Gene: RNF139 (ring finger protein 139)
Type: protein-coding
Summary: The protein encoded by this gene is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be... |
Does Knockout of LSM7 in Chronic Myeloid Leukemia Cell Line causally result in cell proliferation? | 1 | 149 | Knockout | LSM7 | cell proliferation | Chronic Myeloid Leukemia Cell Line | Gene: LSM7 (LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated)
Type: protein-coding
Summary: Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2; MIM 601061). Sm-like proteins contain the Sm sequence motif, which c... |
Does Knockout of SNRPB2 in Prostate Cancer Cell Line causally result in cell proliferation? | 1 | 843 | Knockout | SNRPB2 | cell proliferation | Prostate Cancer Cell Line | Gene: SNRPB2 (small nuclear ribonucleoprotein polypeptide B2)
Type: protein-coding
Summary: The protein encoded by this gene associates with stem loop IV of U2 small nuclear ribonucleoprotein (U2 snRNP) in the presence of snRNP-A'. The encoded protein may play a role in pre-mRNA splicing. Autoantibodies... |
Does Knockout of ATP2B2 in Chronic Myeloid Leukemia Cell Line causally result in cell proliferation? | 0 | 149 | Knockout | ATP2B2 | cell proliferation | Chronic Myeloid Leukemia Cell Line | Gene: ATP2B2 (ATPase plasma membrane Ca2+ transporting 2)
Type: protein-coding
Summary: The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove biva... |
Does Knockout of ZSCAN30 in Chronic Myeloid Leukemia Cell Line causally result in response to chemicals? | 1 | 1,397 | Knockout | ZSCAN30 | response to chemicals | Chronic Myeloid Leukemia Cell Line | Gene: ZSCAN30 (zinc finger and SCAN domain containing 30)
Type: protein-coding
Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of ... |
Does Knockout of NCL in Neuroblastoma Cell Line causally result in cell proliferation? | 1 | 824 | Knockout | NCL | cell proliferation | Neuroblastoma Cell Line | Gene: NCL (nucleolin)
Type: protein-coding
Summary: Nucleolin (NCL), a eukaryotic nucleolar phosphoprotein, is involved in the synthesis and maturation of ribosomes. It is located mainly in dense fibrillar regions of the nucleolus. Human NCL gene consists of 14 exons with 13 introns and spans approximat... |
Does Knockout of MRPL45 in Melanoma Cell Line causally result in cell proliferation? | 1 | 527 | Knockout | MRPL45 | cell proliferation | Melanoma Cell Line | Gene: MRPL45 (mitochondrial ribosomal protein L45)
Type: protein-coding
Summary: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit.... |
Does Knockout of C22orf23 in Lung Adenocarcinoma Cell Line causally result in cell proliferation? | 0 | 897 | Knockout | C22orf23 | cell proliferation | Lung Adenocarcinoma Cell Line | Gene: C22orf23 (chromosome 22 open reading frame 23)
Type: protein-coding
Summary: chromosome 22 open reading frame 23
Gene Ontology:
Pathways:
UniProt: Q9BZE7
Entrez ID: 84645 |
Does Knockout of TAF10 in T-lymphoma cell line causally result in cell proliferation? | 1 | 478 | Knockout | TAF10 | cell proliferation | T-lymphoma cell line | Gene: TAF10 (TATA-box binding protein associated factor 10)
Type: protein-coding
Summary: Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core prom... |
Does Activation of COMMD4 in T cell causally result in protein/peptide accumulation? | 0 | 2,426 | Activation | COMMD4 | protein/peptide accumulation | T cell | Gene: COMMD4 (COMM domain containing 4)
Type: protein-coding
Summary: Located in cytosol; intracellular membrane-bounded organelle; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: CC: cytoplasm, cytosol, nucleus, plasma membrane
Pathways: Metabo... |
Does Knockout of FGF18 in Monocytic Leukemia Cell Line causally result in cell proliferation? | 0 | 80 | Knockout | FGF18 | cell proliferation | Monocytic Leukemia Cell Line | Gene: FGF18 (fibroblast growth factor 18)
Type: protein-coding
Summary: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including emb... |
Does Knockout of JARID2 in Lung Adenocarcinoma Cell Line causally result in cell proliferation? | 0 | 897 | Knockout | JARID2 | cell proliferation | Lung Adenocarcinoma Cell Line | Gene: JARID2 (jumonji and AT-rich interaction domain containing 2)
Type: protein-coding
Summary: This gene encodes a Jumonji- and AT-rich interaction domain (ARID)-domain-containing protein. The encoded protein is a DNA-binding protein that functions as a transcriptional repressor. This protein interact... |
Does Knockout of CDC73 in Endometrial Cancer Cell Line causally result in cell proliferation? | 1 | 758 | Knockout | CDC73 | cell proliferation | Endometrial Cancer Cell Line | Gene: CDC73 (cell division cycle 73)
Type: protein-coding
Summary: This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and... |
Does Knockout of GHRHR in Prostate Cancer Cell Line causally result in cell proliferation? | 0 | 843 | Knockout | GHRHR | cell proliferation | Prostate Cancer Cell Line | Gene: GHRHR (growth hormone releasing hormone receptor)
Type: protein-coding
Summary: This gene encodes a receptor for growth hormone-releasing hormone. Binding of this hormone to the receptor leads to synthesis and release of growth hormone. Mutations in this gene have been associated with isolated gro... |
Does Knockout of ASZ1 in Melanoma Cell Line causally result in cell proliferation? | 0 | 527 | Knockout | ASZ1 | cell proliferation | Melanoma Cell Line | Gene: ASZ1 (ankyrin repeat, SAM and basic leucine zipper domain containing 1)
Type: protein-coding
Summary: Predicted to be involved in gamete generation and piRNA metabolic process. Predicted to be located in cytoplasm. Predicted to be active in pi-body. [provided by Alliance of Genome Resources, Apr 2... |
Does Knockout of NDUFAB1 in Gastric Cancer Cell Line causally result in cell proliferation? | 1 | 787 | Knockout | NDUFAB1 | cell proliferation | Gastric Cancer Cell Line | Gene: NDUFAB1 (NADH:ubiquinone oxidoreductase subunit AB1)
Type: protein-coding
Summary: Predicted to enable acyl binding activity; acyl carrier activity; and fatty acid binding activity. Involved in mitochondrial respiratory chain complex I assembly and protein lipoylation. Located in mitochondrion and... |
Does Knockout of PPA2 in Urinary Bladder Cancer Cell Line causally result in cell proliferation? | 1 | 180 | Knockout | PPA2 | cell proliferation | Urinary Bladder Cancer Cell Line | Gene: PPA2 (inorganic pyrophosphatase 2)
Type: protein-coding
Summary: The protein encoded by this gene is localized to the mitochondrion, is highly similar to members of the inorganic pyrophosphatase (PPase) family, and contains the signature sequence essential for the catalytic activity of PPase. PPas... |
Does Knockout of CDC16 in Gastric Cancer Cell Line causally result in cell proliferation? | 1 | 230 | Knockout | CDC16 | cell proliferation | Gastric Cancer Cell Line | Gene: CDC16 (cell division cycle 16)
Type: protein-coding
Summary: The protein encoded by this gene functions as a protein ubiquitin ligase and is a component of the multiprotein APC complex. The APC complex is a cyclin degradation system that governs exit from mitosis by targeting cell cycle proteins f... |
Does Knockout of TGM6 in Esophageal Squamous Cell Carcinoma Cell Line causally result in cell proliferation? | 0 | 334 | Knockout | TGM6 | cell proliferation | Esophageal Squamous Cell Carcinoma Cell Line | Gene: TGM6 (transglutaminase 6)
Type: protein-coding
Summary: The protein encoded by this gene belongs to the transglutaminase superfamily. It catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. Mutations in this gene are associated with spinocerebellar ataxia type 35 ... |
Does Knockout of WWC1 in Renal Cancer Cell Line causally result in cell proliferation? | 0 | 319 | Knockout | WWC1 | cell proliferation | Renal Cancer Cell Line | Gene: WWC1 (WW and C2 domain containing 1)
Type: protein-coding
Summary: The protein encoded by this gene is a cytoplasmic phosphoprotein that interacts with PRKC-zeta and dynein light chain-1. Alleles of this gene have been found that enhance memory in some individuals. Three transcript variants encodi... |
Does Knockout of MLLT10 in Cervical Adenocarcinoma Cell Line causally result in response to chemicals? | 1 | 1,352 | Knockout | MLLT10 | response to chemicals | Cervical Adenocarcinoma Cell Line | Gene: MLLT10 (MLLT10 histone lysine methyltransferase DOT1L cofactor)
Type: protein-coding
Summary: This gene encodes a transcription factor and has been identified as a partner gene involved in several chromosomal rearrangements resulting in various leukemias. Multiple transcript variants encoding diff... |
Does Knockout of XAB2 in Bladder Carcinoma causally result in cell proliferation? | 1 | 489 | Knockout | XAB2 | cell proliferation | Bladder Carcinoma | Gene: XAB2 (XPA binding protein 2)
Type: protein-coding
Summary: Involved in mRNA splicing, via spliceosome; transcription, DNA-templated; and transcription-coupled nucleotide-excision repair. Located in nucleoplasm. Part of U2-type catalytic step 2 spliceosome. [provided by Alliance of Genome Resources... |
Does Knockout of CADM4 in Lung Adenocarcinoma Cell Line causally result in cell proliferation? | 0 | 897 | Knockout | CADM4 | cell proliferation | Lung Adenocarcinoma Cell Line | Gene: CADM4 (cell adhesion molecule 4)
Type: protein-coding
Summary: Enables vascular endothelial growth factor receptor 2 binding activity. Involved in several processes, including negative regulation of protein phosphorylation; regulation of Rac protein signal transduction; and regulation of wound hea... |
Does Knockout of UBA52 in Neuroblastoma Cell Line causally result in cell proliferation? | 1 | 824 | Knockout | UBA52 | cell proliferation | Neuroblastoma Cell Line | Gene: UBA52 (ubiquitin A-52 residue ribosomal protein fusion product 1)
Type: protein-coding
Summary: Ubiquitin is a highly conserved nuclear and cytoplasmic protein that has a major role in targeting cellular proteins for degradation by the 26S proteosome. It is also involved in the maintenance of chro... |
Does Knockout of PPP1CB in Ewing's Sarcoma Cell Line causally result in cell proliferation? | 1 | 763 | Knockout | PPP1CB | cell proliferation | Ewing's Sarcoma Cell Line | Gene: PPP1CB (protein phosphatase 1 catalytic subunit beta)
Type: protein-coding
Summary: The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of ... |
Does Knockout of PPP1R12A in Oral Squamous Cell Carcinoma Cell Line causally result in cell proliferation? | 1 | 1,311 | Knockout | PPP1R12A | cell proliferation | Oral Squamous Cell Carcinoma Cell Line | Gene: PPP1R12A (protein phosphatase 1 regulatory subunit 12A)
Type: protein-coding
Summary: Myosin phosphatase target subunit 1, which is also called the myosin-binding subunit of myosin phosphatase, is one of the subunits of myosin phosphatase. Myosin phosphatase regulates the interaction of actin and ... |
Does Knockout of SMIM3 in Gastric Cancer Cell Line causally result in cell proliferation? | 0 | 230 | Knockout | SMIM3 | cell proliferation | Gastric Cancer Cell Line | Gene: SMIM3 (small integral membrane protein 3)
Type: protein-coding
Summary: Enables identical protein binding activity. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology: MF: identical protein binding, protein binding
P... |
Does Knockout of ZNHIT6 in Lung Squamous Cell Carcinoma Cell Line causally result in cell proliferation? | 1 | 305 | Knockout | ZNHIT6 | cell proliferation | Lung Squamous Cell Carcinoma Cell Line | Gene: ZNHIT6 (zinc finger HIT-type containing 6)
Type: protein-coding
Summary: Enables ATPase binding activity; TFIID-class transcription factor complex binding activity; and identical protein binding activity. Involved in box C/D snoRNP assembly; protein complex oligomerization; and snoRNA localization... |
Does Knockout of CNPY4 in Lymphoma or Leukaemia Cell Line causally result in protein/peptide accumulation? | 0 | 1,218 | Knockout | CNPY4 | protein/peptide accumulation | Lymphoma or Leukaemia Cell Line | Gene: CNPY4 (canopy FGF signaling regulator 4)
Type: protein-coding
Summary: Predicted to enable signaling receptor binding activity. Involved in positive regulation of protein localization to plasma membrane. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Ap... |
Does Knockout of LSG1 in Medulloblastoma Cell Line causally result in cell proliferation? | 1 | 1,813 | Knockout | LSG1 | cell proliferation | Medulloblastoma Cell Line | Gene: LSG1 (large 60S subunit nuclear export GTPase 1)
Type: protein-coding
Summary: This gene encodes a protein related to the yeast large subunit GTPase 1. The encoded protein is necessary for cell viability and may localize in the endoplasmic reticulum, nucleus and cytoplasm.[provided by RefSeq, Feb ... |
Does Knockout of CD180 in Gastric Cancer Cell Line causally result in cell proliferation? | 0 | 230 | Knockout | CD180 | cell proliferation | Gastric Cancer Cell Line | Gene: CD180 (CD180 molecule)
Type: protein-coding
Summary: CD180 is a cell surface molecule consisting of extracellular leucine-rich repeats (LRR) and a short cytoplasmic tail. The extracellular LRR is associated with a molecule called MD-1 and form the cell surface receptor complex, RP105/MD-1. It belo... |
Does Knockout of NUP205 in Mammary Gland Tumor Cell Line causally result in cell proliferation? | 1 | 220 | Knockout | NUP205 | cell proliferation | Mammary Gland Tumor Cell Line | Gene: NUP205 (nucleoporin 205)
Type: protein-coding
Summary: This gene encodes a nucleoporin, which is a subunit of the nuclear pore complex that functions in active transport of proteins, RNAs and ribonucleoprotein particles between the nucleus and cytoplasm. Mutations in this gene are associated with ... |
Does Knockout of SPTSSA in Mammary Gland Tumor Cell Line causally result in cell proliferation? | 1 | 220 | Knockout | SPTSSA | cell proliferation | Mammary Gland Tumor Cell Line | Gene: SPTSSA (serine palmitoyltransferase small subunit A)
Type: protein-coding
Summary: Serine palmitoyltransferase (SPT; EC 2.3.1.50) catalyzes the first committed and rate-limiting step in sphingolipid biosynthesis. SSSPTA is a small SPT subunit that stimulates SPT activity and confers acyl-CoA prefe... |
Does Knockout of EXPH5 in Lung Squamous Cell Carcinoma Cell Line causally result in cell proliferation? | 0 | 305 | Knockout | EXPH5 | cell proliferation | Lung Squamous Cell Carcinoma Cell Line | Gene: EXPH5 (exophilin 5)
Type: protein-coding
Summary: The protein encoded by this gene is a member of the synaptotagmin-like protein (Slp) family lacking a C2 domain. It contains an N-terminal synaptotagmin-like homology domain (SHD), and is a ras-related protein Rab-27B effector protein. This protein... |
Does Knockout of SLC9A7 in Pre-B Acute Lymphoblastic Leukemia Cell Line causally result in cell proliferation? | 0 | 1,996 | Knockout | SLC9A7 | cell proliferation | Pre-B Acute Lymphoblastic Leukemia Cell Line | Gene: SLC9A7 (solute carrier family 9 member A7)
Type: protein-coding
Summary: This gene encodes a sodium and potassium/ proton antiporter that is a member of the solute carrier family 9 protein family. The encoded protein is primarily localized to the trans-Golgi network and is involved in maintaining ... |
Does Knockout of APOC2 in Glioblastoma Cell Line causally result in cell proliferation? | 0 | 906 | Knockout | APOC2 | cell proliferation | Glioblastoma Cell Line | Gene: APOC2 (apolipoprotein C2)
Type: protein-coding
Summary: This gene encodes a lipid-binding protein belonging to the apolipoprotein gene family. The protein is secreted in plasma where it is a component of very low density lipoprotein. This protein activates the enzyme lipoprotein lipase, which hydr... |
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