screen_file string | organism string | perturbation string | gene string | cell string | phenotype string | hit int64 | benchmark_type string | prompt string | gene_context string |
|---|---|---|---|---|---|---|---|---|---|
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Mta2 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Mta2 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Mta2 (metastasis-associated gene family, member 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: chromatin remodeling, chromosome organization, genomic imprinting, negative regulation of DNA-templated transcription, negative regulation of transcription by RNA poly... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Tpi1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Tpi1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Tpi1 (triosephosphate isomerase 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: canonical glycolysis, gluconeogenesis, glucose metabolic process, glyceraldehyde-3-phosphate biosynthetic process, glyceraldehyde-3-phosphate metabolic process, glycerol catabolic pro... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Atxn7l3 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Atxn7l3 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Atxn7l3 (ataxin 7-like 3)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: chromatin organization, positive regulation of DNA-templated transcription, regulation of DNA repair, regulation of RNA splicing, regulation of transcription by RNA polymerase II; MF: metal io... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Fam98b | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Fam98b in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Fam98b (family with sequence similarity 98, member B)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: positive regulation of cell population proliferation, positive regulation of gene expression, protein methylation; MF: identical protein binding, protein methyltran... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Heatr3 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Heatr3 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Heatr3 (HEAT repeat containing 3)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: erythrocyte maturation, protein import into nucleus, ribosomal large subunit biogenesis, ribosome biogenesis
Pathways:
UniProt: Q8BQM4
Entrez ID: 234549 |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Pds5b | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Pds5b in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Pds5b (PDS5 cohesin associated factor B)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cell division, lens development in camera-type eye, mitotic sister chromatid cohesion, negative regulation of cell population proliferation, regulation of cell population prolif... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Gnl3l | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Gnl3l in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Gnl3l (guanine nucleotide binding protein nucleolar 3 like)
Type: protein-coding
Summary: Predicted to enable GTP binding activity. Predicted to be involved in several processes, including negative regulation of protein modification by small protein conjugation or removal; negative regulation of t... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Haus1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Haus1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Haus1 (HAUS augmin-like complex, subunit 1)
Type: protein-coding
Summary: Predicted to be involved in centrosome cycle and spindle assembly. Predicted to be located in centrosome and mitotic spindle microtubule. Predicted to be part of HAUS complex. Predicted to be active in cytosol. Is expressed ... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Taf11 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Taf11 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Taf11 (TATA-box binding protein associated factor 11)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA polymerase II preinitiation complex assembly, host-mediated activation of viral transcription, mRNA transcription by RNA polymerase II, positive regulation of t... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Strap | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Strap in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Strap (serine/threonine kinase receptor associated protein)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA splicing, alternative mRNA splicing, via spliceosome, mRNA processing, mRNA splicing, via spliceosome, maintenance of gastrointestinal epithelium, negativ... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Heatr1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Heatr1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Heatr1 (HEAT repeat containing 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), neural precursor cell proliferation, positive regulation of rRNA processing, positive regulati... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Birc5 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Birc5 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Birc5 (baculoviral IAP repeat-containing 5)
Type: protein-coding
Summary: This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) dom... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Wdr5 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Wdr5 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Wdr5 (WD repeat domain 5)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: chromatin organization, negative regulation of transcription by RNA polymerase II, neuron projection development, positive regulation of DNA-templated transcription, positive regulation of glu... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Nip7 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Nip7 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Nip7 (NIP7, nucleolar pre-rRNA processing protein)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: ribosomal large subunit biogenesis, ribosome assembly, ribosome biogenesis; CC: cytoplasm, cytosol, nucleolus, nucleoplasm, nucleus, preribosome, large subunit precurs... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Psmc5 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Psmc5 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Psmc5 (protease (prosome, macropain) 26S subunit, ATPase 5)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: negative regulation of DNA-templated transcription, positive regulation of inclusion body assembly, proteasome-mediated ubiquitin-dependent protein catabolic ... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Ppcdc | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Ppcdc in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Ppcdc (phosphopantothenoylcysteine decarboxylase)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: coenzyme A biosynthetic process; MF: FMN binding, carboxy-lyase activity, catalytic activity, identical protein binding, lyase activity, phosphopantothenoylcysteine dec... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Cbll1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Cbll1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Cbll1 (Casitas B-lineage lymphoma-like 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cell-cell adhesion, mRNA processing, negative regulation of cell adhesion, positive regulation of cell migration, positive regulation of endocytosis, protein ubiquitination, re... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Vars2 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Vars2 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Vars2 (valyl-tRNA synthetase 2, mitochondrial)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: aminoacyl-tRNA metabolism involved in translational fidelity, tRNA aminoacylation for protein translation, translation, valyl-tRNA aminoacylation; MF: ATP binding, aminoac... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Mrpl38 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Mrpl38 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Mrpl38 (mitochondrial ribosomal protein L38)
Type: protein-coding
Summary: No summary available.
Gene Ontology: CC: cytosol, mitochondrial inner membrane, mitochondrial large ribosomal subunit, mitochondrial ribosome, mitochondrion, ribonucleoprotein complex, ribosome
Pathways: M... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Hsd17b10 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Hsd17b10 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Hsd17b10 (hydroxysteroid (17-beta) dehydrogenase 10)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: C21-steroid hormone metabolic process, L-isoleucine catabolic process, androgen metabolic process, bile acid biosynthetic process, brexanolone metabolic process, est... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Pyroxd1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Pyroxd1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Pyroxd1 (pyridine nucleotide-disulphide oxidoreductase domain 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cellular response to oxidative stress; MF: NAD(P)H oxidase H2O2-forming activity, molecular_function, oxidoreductase activity; CC: cytoplasm, nucleus, sa... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Timm10 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Timm10 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Timm10 (translocase of inner mitochondrial membrane 10)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: protein insertion into mitochondrial inner membrane, protein transport; MF: membrane insertase activity, metal ion binding, protein homodimerization activity, pro... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Mrps15 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Mrps15 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Mrps15 (mitochondrial ribosomal protein S15)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: mitochondrial translation, translation; MF: protein binding, structural constituent of ribosome; CC: mitochondrial inner membrane, mitochondrial matrix, mitochondrial riboso... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Toe1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Toe1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Toe1 (target of EGR1, member 1 (nuclear))
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA metabolic process, snRNA 3'-end processing; MF: 3'-5'-RNA exonuclease activity, metal ion binding, nucleic acid binding, poly(A)-specific ribonuclease activity, snRNA bindi... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Nudcd2 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Nudcd2 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Nudcd2 (NudC domain containing 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: CC: centrosome, chromosome, chromosome, centromeric region, cytoplasm, cytoskeleton, cytosol, intercellular bridge, kinetochore, microtubule cytoskeleton, mitotic spindle, spindle pole
... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Nufip1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Nufip1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Nufip1 (nuclear FMR1 interacting protein 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: box C/D snoRNP assembly, positive regulation of transcription by RNA polymerase II; MF: ATPase binding, RNA binding, identical protein binding, metal ion binding, protein bin... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Dhx33 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Dhx33 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Dhx33 (DEAH-box helicase 33)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: positive regulation of MAPK cascade, positive regulation of NF-kappaB transcription factor activity, positive regulation of NLRP3 inflammasome complex assembly, positive regulation of trans... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Noc4l | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Noc4l in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Noc4l (NOC4 like)
Type: protein-coding
Summary: No summary available.
Gene Ontology: CC: Noc4p-Nop14p complex, membrane, nuclear membrane, nucleolus, nucleoplasm, nucleus, small-subunit processome
Pathways: Major pathway of rRNA processing in the nucleolus and cytosol, Metabolism... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Ndufa1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Ndufa1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Ndufa1 (NADH:ubiquinone oxidoreductase subunit A1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: aerobic respiration, proton motive force-driven mitochondrial ATP synthesis; CC: membrane, mitochondrial inner membrane, mitochondrial membrane, mitochondrion, respira... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Rps27rt | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Rps27rt in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Rps27rt (ribosomal protein S27, retrogene)
Type: protein-coding
Summary: No summary available.
Gene Ontology:
Pathways: Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S, Amplification of signal from unattached kinetochores ... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Tiprl | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Tiprl in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Tiprl (TIP41, TOR signalling pathway regulator-like (S. cerevisiae))
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA damage checkpoint signaling, TOR signaling; MF: molecular_function, protein phosphatase activator activity, protein phosphatase inhibitor activit... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Nat10 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Nat10 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Nat10 (N-acetyltransferase 10)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA modification, negative regulation of telomere maintenance via telomerase, positive regulation of translation, protein acetylation, rRNA acetylation involved in maturation of SSU-rRNA,... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Flii | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Flii in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Flii (flightless I actin binding protein)
Type: protein-coding
Summary: This gene encodes a protein with gelsolin-like repeats and an N-terminal leucine-rich repeat domain. The protein is similar to a Drosophila protein involved in early embryogenesis and the structural organization of indirect fl... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Eral1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Eral1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Eral1 (Era like 12S mitochondrial rRNA chaperone 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: ribosomal small subunit assembly, ribosome biogenesis; MF: GTP binding, RNA binding, nucleotide binding, rRNA binding, ribosomal small subunit binding; CC: cytosol, m... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Tsr1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Tsr1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Tsr1 (TSR1 20S rRNA accumulation)
Type: protein-coding
Summary: Predicted to enable GTP binding activity; GTPase activity; and U3 snoRNA binding activity. Predicted to be involved in endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) and maturation of SSU-rRNA... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Ing1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Ing1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Ing1 (inhibitor of growth family, member 1)
Type: protein-coding
Summary: Predicted to enable methylated histone binding activity. Acts upstream of or within positive regulation of DNA-templated transcription; protein import into nucleus; and regulation of programmed cell death. Located in nucleus... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Rpl37 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Rpl37 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Rpl37 (ribosomal protein L37)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cytoplasmic translation, positive regulation of signal transduction by p53 class mediator, translation, translation at postsynapse, translation at presynapse; MF: MDM2/MDM4 family protein ... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Nop10 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Nop10 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Nop10 (NOP10 ribonucleoprotein)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: pseudouridine synthesis, rRNA processing, rRNA pseudouridine synthesis, ribosome biogenesis, snRNA pseudouridine synthesis, snoRNA guided rRNA pseudouridine synthesis, telomere maintenan... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Mrps34 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Mrps34 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Mrps34 (mitochondrial ribosomal protein S34)
Type: protein-coding
Summary: Predicted to be a structural constituent of ribosome. Involved in mitochondrial translation. Located in mitochondrion. Is expressed in several structures, including early conceptus; genitourinary system; heart; liver; and t... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Cpsf4 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Cpsf4 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Cpsf4 (cleavage and polyadenylation specific factor 4)
Type: protein-coding
Summary: No summary available.
Gene Ontology: MF: RNA binding, metal ion binding, nucleic acid binding, sequence-specific double-stranded DNA binding, zinc ion binding; CC: mRNA cleavage and polyadenylation specif... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Wdr25 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Wdr25 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Wdr25 (WD repeat domain 25)
Type: protein-coding
Summary: No summary available.
Gene Ontology:
Pathways:
UniProt: E9Q349
Entrez ID: 212198 |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Rps10 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Rps10 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Rps10 (ribosomal protein S10)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cytoplasmic translation, ribosomal small subunit assembly, translation at postsynapse, translation at presynapse; MF: RNA binding, structural constituent of ribosome, tRNA binding; CC: cyt... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Dars2 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Dars2 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Dars2 (aspartyl-tRNA synthetase 2 (mitochondrial))
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: aspartyl-tRNA aminoacylation, mitochondrial asparaginyl-tRNA aminoacylation, tRNA aminoacylation, tRNA aminoacylation for protein translation, translation; MF: ATP bin... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Mrpl44 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Mrpl44 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Mrpl44 (mitochondrial ribosomal protein L44)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA processing, mitochondrial translation, mitochondrial translational elongation; MF: RNA binding, double-stranded RNA binding, endonuclease activity, hydrolase activity, n... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Pabpn1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Pabpn1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Pabpn1 (poly(A) binding protein, nuclear 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: MAPK cascade, cellular response to lipopolysaccharide, mRNA processing, poly(A)+ mRNA export from nucleus, positive regulation of polynucleotide adenylyltransferase activity,... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Eif5 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Eif5 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Eif5 (eukaryotic translation initiation factor 5)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: formation of cytoplasmic translation initiation complex, regulation of translational initiation, ribosome assembly, translation, translational initiation; MF: GDP-disso... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Rfk | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Rfk in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Rfk (riboflavin kinase)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: FMN biosynthetic process, apoptotic process, flavin adenine dinucleotide biosynthetic process, reactive oxygen species metabolic process, riboflavin biosynthetic process, riboflavin metabolic pr... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Nup98 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Nup98 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Nup98 (nucleoporin 98)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA export from nucleus, mRNA transport, nuclear pore complex assembly, nucleocytoplasmic transport, positive regulation of DNA-templated transcription, positive regulation of mRNA splicing, via ... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Srd5a3 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Srd5a3 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Srd5a3 (steroid 5 alpha-reductase 3)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: dolichol-linked oligosaccharide biosynthetic process, dolichyl monophosphate biosynthetic process, lipid metabolic process, polyprenol catabolic process, protein glycosylation; MF: ... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Eif4b | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Eif4b in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Eif4b (eukaryotic translation initiation factor 4B)
Type: protein-coding
Summary: Predicted to enable RNA strand annealing activity; RNA strand-exchange activity; and ribosomal small subunit binding activity. Predicted to be involved in eukaryotic translation initiation factor 4F complex assembly ... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Lsm11 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Lsm11 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Lsm11 (U7 snRNP-specific Sm-like protein LSM11)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: mRNA 3'-end processing by stem-loop binding and cleavage, mRNA processing, positive regulation of G1/S transition of mitotic cell cycle, regulation of chromatin organizat... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Rpl17 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Rpl17 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Rpl17 (ribosomal protein L17)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cellular response to amino acid starvation, cytoplasmic translation, positive regulation of G1/S transition of mitotic cell cycle, response to amino acid starvation, translation, translati... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Sephs2 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Sephs2 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Sephs2 (selenophosphate synthetase 2)
Type: protein-coding
Summary: This gene encodes an enzyme that catalyzes the production of monoselenophosphate (MSP) from selenide and ATP. MSP is the selenium donor required for synthesis of selenocysteine (Sec), which is co-translationally incorporated into ... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Adat3 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Adat3 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Adat3 (adenosine deaminase, tRNA-specific 3)
Type: protein-coding
Summary: Predicted to enable catalytic activity and metal ion binding activity. Predicted to contribute to tRNA-specific adenosine-34 deaminase activity. Predicted to be involved in tRNA processing. Predicted to be active in cytopla... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Aasdhppt | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Aasdhppt in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Aasdhppt (aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: 10-formyltetrahydrofolate catabolic process, lysine biosynthetic process via aminoadipic acid, protein maturation; MF: holo-[acyl-carri... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Sars2 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Sars2 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Sars2 (seryl-aminoacyl-tRNA synthetase 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: mitochondrial seryl-tRNA aminoacylation, seryl-tRNA aminoacylation, tRNA aminoacylation for protein translation, translation; MF: ATP binding, aminoacyl-tRNA ligase activity, l... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Dhodh | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Dhodh in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Dhodh (dihydroorotate dehydrogenase)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: 'de novo' UMP biosynthetic process, 'de novo' pyrimidine nucleobase biosynthetic process, UDP biosynthetic process, positive regulation of apoptotic process, pyrimidine nucleotide b... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Ubtf | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Ubtf in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Ubtf (upstream binding transcription factor, RNA polymerase I)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA polymerase I preinitiation complex assembly, cellular response to leukemia inhibitory factor, positive regulation of transcription by RNA polymerase I,... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Nelfcd | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Nelfcd in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Nelfcd (negative elongation factor complex member C/D, Th1l)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: negative regulation of DNA-templated transcription, negative regulation of transcription elongation by RNA polymerase II; MF: RNA binding, protein binding; C... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Atl2 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Atl2 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Atl2 (atlastin GTPase 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: Golgi organization, cellular response to type II interferon, endoplasmic reticulum membrane fusion, endoplasmic reticulum organization, endoplasmic reticulum tubular network membrane organizati... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Pin1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Pin1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Pin1 (peptidyl-prolyl cis/trans isomerase, NIMA-interacting 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: Rho protein signal transduction, cellular response to hypoxia, negative regulation of ERK1 and ERK2 cascade, negative regulation of SMAD protein signal tra... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Cmtr2 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Cmtr2 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Cmtr2 (cap methyltransferase 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: 7-methylguanosine mRNA capping, mRNA processing, methylation; MF: methyltransferase activity, methyltransferase cap1 activity, methyltransferase cap2 activity, transferase activity; CC: ... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Rps15 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Rps15 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Rps15 (ribosomal protein S15)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cytoplasmic translation, liver regeneration, positive regulation of signal transduction by p53 class mediator, rRNA processing, ribosomal small subunit assembly, ribosomal small subunit bi... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Zcchc9 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Zcchc9 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Zcchc9 (zinc finger, CCHC domain containing 9)
Type: protein-coding
Summary: No summary available.
Gene Ontology: MF: metal ion binding, nucleic acid binding, zinc ion binding; CC: nucleolus, nucleoplasm, nucleus
Pathways:
UniProt: Q8R1J3
Entrez ID: 69085 |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Eef1g | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Eef1g in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Eef1g (eukaryotic translation elongation factor 1 gamma)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: response to virus, translation, translational elongation; CC: cytoplasm, endoplasmic reticulum, nucleus
Pathways: Eukaryotic Translation Elongation, Leg... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Mrpl20 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Mrpl20 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Mrpl20 (mitochondrial ribosomal protein L20)
Type: protein-coding
Summary: Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Predicted to act upstream of or within translation. Located in mitochondrion. Is expressed in several structures, ... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Wdr77 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Wdr77 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Wdr77 (WD repeat domain 77)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: negative regulation of cell population proliferation, negative regulation of epithelial cell proliferation involved in prostate gland development, oocyte axis specification, positive regulat... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Rpl3 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Rpl3 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Rpl3 (ribosomal protein L3)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cellular response to interleukin-4, cytoplasmic translation, translation; MF: 5S rRNA binding, RNA binding, structural constituent of ribosome; CC: cytoplasm, cytosol, cytosolic large riboso... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Chordc1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Chordc1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Chordc1 (cysteine and histidine rich domain containing 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: centrosome duplication, negative regulation of Rho-dependent protein serine/threonine kinase activity, protein folding, regulation of cellular response to heat,... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Mettl23 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Mettl23 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Mettl23 (methyltransferase like 23)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: chromatin organization, cognition, epigenetic programing of male pronucleus, epigenetic programming in the zygotic pronuclei, epigenetic regulation of gene expression, methylation, p... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Cstf3 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Cstf3 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Cstf3 (cleavage stimulation factor, 3' pre-RNA, subunit 3)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA 3'-end processing, RNA processing, co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway, mRNA 3'-end processing, mRNA processing... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Alad | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Alad in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Alad (aminolevulinate, delta-, dehydratase)
Type: protein-coding
Summary: Enables porphobilinogen synthase activity. Involved in heme A biosynthetic process; heme B biosynthetic process; and heme O biosynthetic process. Acts upstream of or within cellular response to interleukin-4 and heme biosynt... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Eif3b | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Eif3b in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Eif3b (eukaryotic translation initiation factor 3, subunit B)
Type: protein-coding
Summary: Contributes to translation initiation factor activity. Involved in translational initiation. Part of eukaryotic translation initiation factor 3 complex, eIF3m. Is active in synapse. Is expressed in several ... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Vps11 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Vps11 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Vps11 (VPS11, CORVET/HOPS core subunit)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: autophagy, endosomal vesicle fusion, endosome organization, endosome to lysosome transport, intracellular protein transport, negative regulation of intracellular estrogen recepto... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Mms19 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Mms19 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Mms19 (MMS19 cytosolic iron-sulfur assembly component)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA damage response, DNA repair, chromosome segregation, positive regulation of DNA-templated transcription, protein maturation; MF: enzyme binding, nuclear estrog... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Ctr9 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Ctr9 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Ctr9 (CTR9 homolog, Paf1/RNA polymerase II complex component)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: Wnt signaling pathway, blastocyst growth, blastocyst hatching, cell surface receptor signaling pathway via JAK-STAT, cellular response to lipopolysaccharide... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Snrpg | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Snrpg in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Snrpg (small nuclear ribonucleoprotein polypeptide G)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA splicing, mRNA processing, mRNA splicing, via spliceosome, spliceosomal snRNP assembly; MF: RNA binding, U1 snRNP binding; CC: P granule, SMN-Sm protein complex... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Dnajc2 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Dnajc2 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Dnajc2 (DnaJ heat shock protein family (Hsp40) member C2)
Type: protein-coding
Summary: Predicted to enable several functions, including Hsp70 protein binding activity; ribosome binding activity; and ubiquitin-modified histone reader activity. Acts upstream of or within DNA replication and negativ... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Tpt1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Tpt1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Tpt1 (tumor protein, translationally-controlled 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: negative regulation of ectoderm development, negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage, response to virus, spermatogenesis... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Cdk2ap1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Cdk2ap1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Cdk2ap1 (cyclin dependent kinase 2 associated protein 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: face morphogenesis, in utero embryonic development, regulation of transcription by RNA polymerase II; CC: NuRD complex, chromatin, chromosome, cytoplasm, cytosol... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Ruvbl1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Ruvbl1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Ruvbl1 (RuvB-like AAA ATPase 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA damage response, DNA recombination, DNA repair, box C/D snoRNP assembly, cell division, chromatin organization, chromatin remodeling, positive regulation of DNA repair, positive regu... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Zbtb8os | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Zbtb8os in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Zbtb8os (zinc finger and BTB domain containing 8 opposite strand)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: tRNA processing, tRNA splicing, via endonucleolytic cleavage and ligation; MF: metal ion binding, molecular_function; CC: tRNA-splicing ligase complex
... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Mup16 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Mup16 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Mup16 (major urinary protein 16)
Type: protein-coding
Summary: No summary available.
Gene Ontology:
Pathways:
UniProt: P02762
Entrez ID: 100039177 |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Dclre1b | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Dclre1b in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Dclre1b (DNA cross-link repair 1B)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA damage response, DNA repair, double-strand break repair via nonhomologous end joining, interstrand cross-link repair, nucleotide-excision repair, protection from non-homologous en... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Erh | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Erh in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Erh (ERH mRNA splicing and mitosis factor)
Type: protein-coding
Summary: No summary available.
Gene Ontology: MF: methyl-CpG binding; CC: membrane, methylosome, midbody, nucleus
Pathways:
UniProt: P84089
Entrez ID: 13877 |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Rps8 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Rps8 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Rps8 (ribosomal protein S8)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cytoplasmic translation, maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), ribosomal small subunit biogenesis, translation; MF: structural constituent... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Ddx47 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Ddx47 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Ddx47 (DEAD box helicase 47)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA splicing, apoptotic process, extrinsic apoptotic signaling pathway via death domain receptors, mRNA processing, rRNA processing, ribosome biogenesis; MF: ATP binding, ATP hydrolysis act... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Myc | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Myc in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Myc (myelocytomatosis oncogene)
Type: protein-coding
Summary: The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of spe... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Kansl3 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Kansl3 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Kansl3 (KAT8 regulatory NSL complex subunit 3)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: chromatin organization, positive regulation of DNA-templated transcription, positive regulation of transcription by RNA polymerase II, regulation of mitochondrial transcri... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Ogdh | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Ogdh in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Ogdh (oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide))
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: 2-oxoglutarate decarboxylation to succinyl-CoA, 2-oxoglutarate metabolic process, cerebellar cortex development, generation of precursor metabolites a... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Ttf1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Ttf1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Ttf1 (transcription termination factor, RNA polymerase I)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA-templated transcription termination, chromatin remodeling, negative regulation of DNA replication, termination of RNA polymerase I transcription, transcript... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Nup133 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Nup133 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Nup133 (nucleoporin 133)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: animal organ development, mRNA export from nucleus, mRNA transport, nephron development, neural tube development, neurogenesis, nuclear pore organization, nucleocytoplasmic transport, paraxial ... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Tbp | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Tbp in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Tbp (TATA box binding protein)
Type: protein-coding
Summary: Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and RNA polymerase II-specific DNA-binding transcription factor binding activity. Acts upstream of or within transcription by RNA polymerase II and tr... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Rpl41 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Rpl41 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Rpl41 (ribosomal protein L41)
Type: protein-coding
Summary: A structural constituent of ribosome. Predicted to be involved in cytoplasmic translation. Located in cytoplasm. Part of cytosolic large ribosomal subunit. Orthologous to human RPL41 (ribosomal protein L41). [provided by Alliance of Genom... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Dmap1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Dmap1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Dmap1 (DNA methyltransferase 1-associated protein 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA repair, chromatin organization, chromatin remodeling, negative regulation of DNA-templated transcription, negative regulation of transcription by RNA polymerase ... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Adnp | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Adnp in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Adnp (activity-dependent neuroprotective protein)
Type: protein-coding
Summary: This gene encodes a member of a protein family characterized by nine zinc finger motifs followed by a homeobox domain. In vitro studies demonstrate that the encoded protein interacts with the brahma-related gene1-assoc... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Nob1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Nob1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Nob1 (NIN1/RPN12 binding protein 1 homolog)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: maturation of SSU-rRNA, ribosomal small subunit biogenesis, visual perception; MF: RNA endonuclease activity, endonuclease activity, hydrolase activity, metal ion binding, nu... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Ctc1 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Ctc1 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Ctc1 (CTS telomere maintenance complex component 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA damage response, bone marrow development, chromosome organization, hematopoietic stem cell proliferation, multicellular organism growth, negative regulation of te... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Nup54 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Nup54 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Nup54 (nucleoporin 54)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: NLS-bearing protein import into nucleus, mRNA transport, nuclear pore organization, nucleocytoplasmic transport, protein localization to nuclear inner membrane, protein targeting, protein transpo... |
SCREEN_18_HITS_ONLY.tsv | mouse | knockout | Rplp0 | NG2-3112 mouse glioblastoma cells | increased sensitivity to gliocidin and subsequently glioblastoma cell death | 0 | difficult | Does knockout of Rplp0 in NG2-3112 mouse glioblastoma cells causally result in increased sensitivity to gliocidin and subsequently glioblastoma cell death? | Gene: Rplp0 (ribosomal protein lateral stalk subunit P0)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cellular response to interleukin-4, cytoplasmic translation, ribosome biogenesis; MF: large ribosomal subunit rRNA binding, peptide binding, structural constituent of ... |
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