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pubmed23n0125_13877
Effects of workload and analysis time on the cost of out-of-hours investigations.
In the UK, under present Whitley Council Regulations for payment for out-of-hours pathology services, there is a complex relationship between the number of requests received, the time taken to analyse each request, and the number of calls for which payment may be claimed for work done. At a fixed average analysis time,...
Effects of workload and analysis time on the cost of out-of-hours investigations. In the UK, under present Whitley Council Regulations for payment for out-of-hours pathology services, there is a complex relationship between the number of requests received, the time taken to analyse each request, and the number of calls...
3,767,283
pubmed23n0125_13878
HDL-cholesterol subfractions in healthy males: relation to serum triglyceride levels and age.
The relationship between plasma HDL-cholesterol subfractions (HDL2 and HDL3), measured using a differential precipitation method, and serum triglycerides, was studied in 402 healthy Caucasian males attending a health screening centre in London. Mean values for HDL2 and HDL3 were 0.42 +/- 0.24 mmol/L and 0.81 +/- 0.15 m...
HDL-cholesterol subfractions in healthy males: relation to serum triglyceride levels and age. The relationship between plasma HDL-cholesterol subfractions (HDL2 and HDL3), measured using a differential precipitation method, and serum triglycerides, was studied in 402 healthy Caucasian males attending a health screening...
3,767,284
pubmed23n0125_13879
A method for the identification of apolipoprotein E isoforms employing chemical precipitation and flat bed isoelectric focusing in agarose.
A method is described for the identification of apolipoprotein E phenotypes. Lipoproteins were precipitated by magnesium chloride/phosphotungstate reagent and isoelectric focusing performed on flat-bed agarose. Sensitivity was enhanced by blotting with nitrocellulose prior to staining. The system described requires no ...
A method for the identification of apolipoprotein E isoforms employing chemical precipitation and flat bed isoelectric focusing in agarose. A method is described for the identification of apolipoprotein E phenotypes. Lipoproteins were precipitated by magnesium chloride/phosphotungstate reagent and isoelectric focusing ...
3,767,285
pubmed23n0125_13880
The use of different lipids to express serum tocopherol: lipid ratios for the measurement of vitamin E status.
Plasma tocopherol was measured in 85 alcoholic patients and 40 control subjects from a local factory. Cholesterol, triglycerides and phospholipids were measured individually and summed to give an estimate of total serum lipids. Plasma tocopherol concentrations of the alcoholics were significantly lower than those of th...
The use of different lipids to express serum tocopherol: lipid ratios for the measurement of vitamin E status. Plasma tocopherol was measured in 85 alcoholic patients and 40 control subjects from a local factory. Cholesterol, triglycerides and phospholipids were measured individually and summed to give an estimate of t...
3,767,286
pubmed23n0125_13881
delta-Aminolaevulinic acid dehydratase as an index of the presence and severity of lead poisoning in acute and chronic lead exposure.
The activity of delta-aminolaevulinic acid dehydratase (ALA-D; porphobilinogen synthase) was measured in whole blood from a group of workers with acute exposure to lead and with low blood lead levels, a group of workers with chronic lead exposure and high blood lead levels, and a group of people without undue environme...
delta-Aminolaevulinic acid dehydratase as an index of the presence and severity of lead poisoning in acute and chronic lead exposure. The activity of delta-aminolaevulinic acid dehydratase (ALA-D; porphobilinogen synthase) was measured in whole blood from a group of workers with acute exposure to lead and with low bloo...
3,767,287
pubmed23n0125_13882
Simple screening methods for hypoxanthine-guanine phosphoribosyltransferase and adenine phosphoribosyltransferase deficiencies using dried blood spots on filter paper.
Simple methods for the detection of hypoxanthine-guanine phosphoribosyltransferase and/or adenine phosphoribosyltransferase deficiencies using dried filter paper blood spots were studied. Enzyme activities in the eluate from dried filter paper blood spots stored for 4 weeks at room conditions were shown to be quite sta...
Simple screening methods for hypoxanthine-guanine phosphoribosyltransferase and adenine phosphoribosyltransferase deficiencies using dried blood spots on filter paper. Simple methods for the detection of hypoxanthine-guanine phosphoribosyltransferase and/or adenine phosphoribosyltransferase deficiencies using dried fil...
3,767,288
pubmed23n0125_13883
The adjusted serum calcium concept--a reappraisal.
The relationship between serum calcium and albumin was studied using a data base containing biochemical results on approximately 687,000 samples. To exclude patients with established bone, liver and kidney disease, calcium and albumin values had to be accompanied by additional results falling within the laboratory refe...
The adjusted serum calcium concept--a reappraisal. The relationship between serum calcium and albumin was studied using a data base containing biochemical results on approximately 687,000 samples. To exclude patients with established bone, liver and kidney disease, calcium and albumin values had to be accompanied by ad...
3,767,289
pubmed23n0125_13884
Measurement of erythrocyte acetylcholinesterase and plasma cholinesterase activity by a differential pH technique.
We describe a new electrochemical method for the determination of erythrocyte acetylcholinesterase activity (EC 3.1.1.7) and plasma cholinesterase (EC 3.1.1.8) activity, based on the measurements of pH variation due to release of acetic acid from acetylcholine. The major advantages of the differential pH procedure are ...
Measurement of erythrocyte acetylcholinesterase and plasma cholinesterase activity by a differential pH technique. We describe a new electrochemical method for the determination of erythrocyte acetylcholinesterase activity (EC 3.1.1.7) and plasma cholinesterase (EC 3.1.1.8) activity, based on the measurements of pH var...
3,767,290
pubmed23n0125_13885
The interpretation of bloodspot 17 alpha-hydroxyprogesterone levels in term and pre-term neonates.
Bloodspot 17 alpha-hydroxyprogesterone, plasma cortisol, plasma sodium and urinary 17 alpha-hydroxyprogesterone, cortisol, sodium and creatinine levels were determined in 24 term and 32 pre-term infants on the third, eighth and fourteenth days of life. Pre-term infants, whether 'well' or 'sick', had significantly raise...
The interpretation of bloodspot 17 alpha-hydroxyprogesterone levels in term and pre-term neonates. Bloodspot 17 alpha-hydroxyprogesterone, plasma cortisol, plasma sodium and urinary 17 alpha-hydroxyprogesterone, cortisol, sodium and creatinine levels were determined in 24 term and 32 pre-term infants on the third, eigh...
3,767,291
pubmed23n0125_13886
An improved method for measurement of common tricyclic antidepressant drugs and their metabolites using normal phase HPLC.
A sensitive HPLC method that allows the simultaneous determination of imipramine, amitriptyline and their desmethyl metabolites, using a 10 cm straight silica cartridge column with a mobile phase consisting of 0.004% perchloric acid in methanol is presented. Detection of the eluent is at 210 nm. The drugs are back-extr...
An improved method for measurement of common tricyclic antidepressant drugs and their metabolites using normal phase HPLC. A sensitive HPLC method that allows the simultaneous determination of imipramine, amitriptyline and their desmethyl metabolites, using a 10 cm straight silica cartridge column with a mobile phase c...
3,767,292
pubmed23n0125_13887
Mobile phase optimisation in the separation of antiepileptic drugs by high-performance liquid chromatography.
A simple method is described for adjusting the mobile phase composition to obtain optimum separation of commonly prescribed antiepileptic drugs by high-performance liquid chromatography. The drugs are separated, in less than 6 min, on a column of Hypersil ODS 5 microns (100 mm X 5 mm i.d.) with a high mobile phase flow...
Mobile phase optimisation in the separation of antiepileptic drugs by high-performance liquid chromatography. A simple method is described for adjusting the mobile phase composition to obtain optimum separation of commonly prescribed antiepileptic drugs by high-performance liquid chromatography. The drugs are separated...
3,767,293
pubmed23n0125_13888
Changes in plasma and buffy layer vitamin C concentrations following major surgery: what do they reflect?
Plasma and buffy layer vitamin C concentrations have been measured in 19 patients before and following major surgery, and falls of 36% and 43% respectively were recorded on the first post-operative day. However, the change in the buffy layer could not be accounted for by a change in the concentration of vitamin C in pl...
Changes in plasma and buffy layer vitamin C concentrations following major surgery: what do they reflect? Plasma and buffy layer vitamin C concentrations have been measured in 19 patients before and following major surgery, and falls of 36% and 43% respectively were recorded on the first post-operative day. However, th...
3,767,294
pubmed23n0125_13889
Bence Jones protein detection: a rapid immunoblotting technique for routine use on unconcentrated urine.
A new immunoblotting method is described for the detection of Bence Jones proteinuria by the routine laboratory. Unconcentrated urine specimens are subjected to electrophoresis on agarose gels. Separated proteins are transferred to a nitrocellulose membrane and the immunoglobulins located and identified by horseradish-...
Bence Jones protein detection: a rapid immunoblotting technique for routine use on unconcentrated urine. A new immunoblotting method is described for the detection of Bence Jones proteinuria by the routine laboratory. Unconcentrated urine specimens are subjected to electrophoresis on agarose gels. Separated proteins ar...
3,767,295
pubmed23n0125_13890
External quality assessment of serum enzyme activity assays and the effect of calibration on interlaboratory concordance.
The design and results of a UK external quality assessment scheme for six enzymes are described, from 21 surveys over a period of 7 years. Improvements in interlaboratory agreement and the adoption of reliable methods are documented. The potential of enzyme calibration materials in further improving numerical concordan...
External quality assessment of serum enzyme activity assays and the effect of calibration on interlaboratory concordance. The design and results of a UK external quality assessment scheme for six enzymes are described, from 21 surveys over a period of 7 years. Improvements in interlaboratory agreement and the adoption ...
3,767,296
pubmed23n0125_13891
Evaluation of the computing aspects of automatic analysers.
Modern automatic analysers are making increasing use of microprocessor technology, which is difficult for the user, or even computer scientists, to evaluate. This paper offers some practical advice for the prospective purchaser on how to assess the capabilities and limitations of the computer hardware and software prov...
Evaluation of the computing aspects of automatic analysers. Modern automatic analysers are making increasing use of microprocessor technology, which is difficult for the user, or even computer scientists, to evaluate. This paper offers some practical advice for the prospective purchaser on how to assess the capabilitie...
3,767,297
pubmed23n0125_13892
Salivary androgens in hirsutism: are they of use in routine evaluation?
In the biochemical evaluation of hirsutism, 50% or less of patients have an elevated total serum testosterone. Recent work has suggested that measuring salivary testosterone or a derived serum 'free testosterone index' may be of use in the evaluation of hyperandrogenism. We have measured serum total, derived serum free...
Salivary androgens in hirsutism: are they of use in routine evaluation? In the biochemical evaluation of hirsutism, 50% or less of patients have an elevated total serum testosterone. Recent work has suggested that measuring salivary testosterone or a derived serum 'free testosterone index' may be of use in the evaluati...
3,767,298
pubmed23n0125_13893
Indoles in the photoreceptor cells of the lamprey pineal complex.
In the pineal complex of the brook lamprey, the hydroxyindole-0-methyltransferase (involved in the biosynthesis of 5-methoxyindoles) displays a daily rhythm of activity with a nocturnal peak, during a light/dark cycle and in constant darkness. Immunoreactive indoles were found in both varieties of photoreceptor cells (...
Indoles in the photoreceptor cells of the lamprey pineal complex. In the pineal complex of the brook lamprey, the hydroxyindole-0-methyltransferase (involved in the biosynthesis of 5-methoxyindoles) displays a daily rhythm of activity with a nocturnal peak, during a light/dark cycle and in constant darkness. Immunoreac...
3,767,302
pubmed23n0125_13894
Photoreceptors in the teleost pineal organ. Daily fluctuations of indole metabolism.
The present study in the pineal organ of the pike reports the existence of day/night variations in the levels of three indoles, and in the activity of two enzymes involved in their metabolism. Present and previous data indicate that the cone-like (P) and modified (MP) photoreceptors of the pineal organ translate the ph...
Photoreceptors in the teleost pineal organ. Daily fluctuations of indole metabolism. The present study in the pineal organ of the pike reports the existence of day/night variations in the levels of three indoles, and in the activity of two enzymes involved in their metabolism. Present and previous data indicate that th...
3,767,303
pubmed23n0125_13895
[Localization of transcription regulatory sequences. Application to the genes of the prolactin family].
We are studying nucleotide sequences responsible for the regulation of eukaryotic gene expression. Our test system comprises the human genes coding for prolactin (hPRL), growth hormone (hGH-N) and placental lactogen (hCS-B). We have cloned these genes and are searching within their sequences for in vitro binding sites ...
[Localization of transcription regulatory sequences. Application to the genes of the prolactin family]. We are studying nucleotide sequences responsible for the regulation of eukaryotic gene expression. Our test system comprises the human genes coding for prolactin (hPRL), growth hormone (hGH-N) and placental lactogen ...
3,767,304
pubmed23n0125_13896
A recent survey of consanguineous marriages in Japan: religion and socioeconomic class effects.
A survey of consanguineous marriages in Japan was conducted on 1 September 1983 through questionnaires. The total number of couples studied was 9225, chosen from six widely different areas of Japan. Among six religious groups, the mean inbreeding coefficient (F) is the highest in Buddhists (0.0019), and lowest in 'no r...
A recent survey of consanguineous marriages in Japan: religion and socioeconomic class effects. A survey of consanguineous marriages in Japan was conducted on 1 September 1983 through questionnaires. The total number of couples studied was 9225, chosen from six widely different areas of Japan. Among six religious group...
3,767,305
pubmed23n0125_13897
Neuropeptide Y immunoreactivity is reduced in cerebral cortex in Alzheimer's disease.
Neuropeptide Y is a 36-amino acid peptide that is found in high concentrations in cerebral cortex and is contained in cortical neurons. We measured concentrations of this peptide in postmortem tissue from patients with Alzheimer's disease and controls using a sensitive and specific radioimmunoassay. High-performance li...
Neuropeptide Y immunoreactivity is reduced in cerebral cortex in Alzheimer's disease. Neuropeptide Y is a 36-amino acid peptide that is found in high concentrations in cerebral cortex and is contained in cortical neurons. We measured concentrations of this peptide in postmortem tissue from patients with Alzheimer's dis...
3,767,313
pubmed23n0125_13898
Skeletal maturity and body size of teenage Belgian track and field athletes.
Attained skeletal maturity (TW2 RUS method), skeletal maturity relative to chronological age, and body size of national-level Belgian track and field athletes 15 to 18 years of age were considered. Among the 47 male athletes, 29 (62%) were skeletally mature, while 15 (52%) of the 29 female athletes were skeletally matu...
Skeletal maturity and body size of teenage Belgian track and field athletes. Attained skeletal maturity (TW2 RUS method), skeletal maturity relative to chronological age, and body size of national-level Belgian track and field athletes 15 to 18 years of age were considered. Among the 47 male athletes, 29 (62%) were ske...
3,767,306
pubmed23n0125_13899
A cline for glyoxalase I allele frequencies in Italy.
A gradient of glyoxalase I allele frequencies is described in Italian populations. The association between longitude and allele frequency is assessed through simple and multiple correlation, and gene flow is suggested as a major factor in the origin of such a pattern.
A cline for glyoxalase I allele frequencies in Italy. A gradient of glyoxalase I allele frequencies is described in Italian populations. The association between longitude and allele frequency is assessed through simple and multiple correlation, and gene flow is suggested as a major factor in the origin of such a patter...
3,767,307
pubmed23n0125_13900
Local versus universal growth standards: the effect of using NCHS as universal reference.
Lack of local references has brought many fieldworkers to use the NCHS reference or other Western standards to assess the nutritional status of children in different developing countries. Cross-sectional data from 6631 children between 0 and 6 years of age, without signs of protein-energy malnutrition, were collected b...
Local versus universal growth standards: the effect of using NCHS as universal reference. Lack of local references has brought many fieldworkers to use the NCHS reference or other Western standards to assess the nutritional status of children in different developing countries. Cross-sectional data from 6631 children be...
3,767,308
pubmed23n0125_13901
Prognosis of dementia in normal-pressure hydrocephalus after a shunt operation.
Forty patients who had normal-pressure hydrocephalus were examined neuropsychologically before and 12 months after a ventriculoatrial shunt operation. Comparison of the preoperative and postoperative test results showed that cognitive functions improved in 16 patients, were unchanged in 19, and deteriorated in 5. Moreo...
Prognosis of dementia in normal-pressure hydrocephalus after a shunt operation. Forty patients who had normal-pressure hydrocephalus were examined neuropsychologically before and 12 months after a ventriculoatrial shunt operation. Comparison of the preoperative and postoperative test results showed that cognitive funct...
3,767,314
pubmed23n0125_13902
Contrapulsion of saccades and ipsilateral ataxia: a unilateral disorder of the rostral cerebellum.
Contralateral pulsion of saccades and ipsilateral limb ataxia were manifestations of unilateral damage to the rostral cerebellum studied in a patient with occlusion of one superior cerebellar artery. The saccadic disorder consisted of three elements: horizontal saccades away from the lesion during attempted vertical sa...
Contrapulsion of saccades and ipsilateral ataxia: a unilateral disorder of the rostral cerebellum. Contralateral pulsion of saccades and ipsilateral limb ataxia were manifestations of unilateral damage to the rostral cerebellum studied in a patient with occlusion of one superior cerebellar artery. The saccadic disorder...
3,767,315
pubmed23n0125_13903
Adolescent growth in weight and its relation to menarche in contemporary American girls.
Weight measurements at frequent intervals, from age six to adulthood, of 248 contemporary middle-class American girls were fitted to a mathematical model (Preece and Baines 1978). The results are used to examine weight and weight velocity at specified ages, the characteristics of the weight growth spurt and the relatio...
Adolescent growth in weight and its relation to menarche in contemporary American girls. Weight measurements at frequent intervals, from age six to adulthood, of 248 contemporary middle-class American girls were fitted to a mathematical model (Preece and Baines 1978). The results are used to examine weight and weight v...
3,767,310
pubmed23n0125_13904
The incidence and prevalence of multiple sclerosis in Newfoundland and Labrador, 1960-1984.
A study of the incidence and prevalence of multiple sclerosis on the island of Newfoundland between 1960 and 1984 has yielded a current overall prevalence rate of 55.2 per 100,000, but wide variation is noted in the rates for different parts of the island (range, 15.9 to 105.0 per 100,000). The annual incidence rates f...
The incidence and prevalence of multiple sclerosis in Newfoundland and Labrador, 1960-1984. A study of the incidence and prevalence of multiple sclerosis on the island of Newfoundland between 1960 and 1984 has yielded a current overall prevalence rate of 55.2 per 100,000, but wide variation is noted in the rates for di...
3,767,317
pubmed23n0125_13905
Glial growth factor-like activity in Schwann cell tumors.
To determine whether glial growth factor (GGF)-like activity is associated with human Schwann cell tumors, we tested extracts from these tumors for their ability to stimulate the proliferation of rat Schwann cells in culture. Extracts from 3 of 3 bilateral acoustic neuromas and from 5 of 7 unilateral acoustic neuromas ...
Glial growth factor-like activity in Schwann cell tumors. To determine whether glial growth factor (GGF)-like activity is associated with human Schwann cell tumors, we tested extracts from these tumors for their ability to stimulate the proliferation of rat Schwann cells in culture. Extracts from 3 of 3 bilateral acous...
3,767,316
pubmed23n0125_13906
Growth and development of bodyweight, height and head circumference during the first two years of life: quantitative genetic aspects.
Mother-offspring and sib-sib relationships enable estimation of the heritability coefficients (or more accurately, transmissibility coefficients) and the so-called 'genetic correlation' for stature (S), weight (W) and head circumference (HC) in Israeli infants from birth to about two years of age. Heritability coeffici...
Growth and development of bodyweight, height and head circumference during the first two years of life: quantitative genetic aspects. Mother-offspring and sib-sib relationships enable estimation of the heritability coefficients (or more accurately, transmissibility coefficients) and the so-called 'genetic correlation' ...
3,767,311
pubmed23n0125_13907
Borderzone infarctions distal to internal carotid artery occlusion: prognostic implications.
Bilateral watershed (WS) infarction at the borderzone of the middle cerebral artery territory are typically related to severe hypotensive events. Unilateral WS infarctions have sometimes been reported in occlusion of the ipsilateral internal carotid artery (ICA), but their pathogenesis and prognostic implications are p...
Borderzone infarctions distal to internal carotid artery occlusion: prognostic implications. Bilateral watershed (WS) infarction at the borderzone of the middle cerebral artery territory are typically related to severe hypotensive events. Unilateral WS infarctions have sometimes been reported in occlusion of the ipsila...
3,767,318
pubmed23n0125_13908
Electrographic status epilepticus in fatal anoxic coma.
Electrographic status epilepticus in the absence of conspicuous somatic motor manifestations is described in 10 patients who were comatose following anoxic-ischemic brain damage. The outcome was unfavorable and the response to anticonvulsant drugs was poor. We describe a clinical sign predictive of the electroencephalo...
Electrographic status epilepticus in fatal anoxic coma. Electrographic status epilepticus in the absence of conspicuous somatic motor manifestations is described in 10 patients who were comatose following anoxic-ischemic brain damage. The outcome was unfavorable and the response to anticonvulsant drugs was poor. We des...
3,767,319
pubmed23n0125_13909
Geographic distribution of consanguinity in Europe.
Average consanguinity (alpha) of 20 large regional or national samples derived from Roman Catholic Dispensations or state archives shows a strong negative relationship with latitude (r = -0.738; P less than 0.001) which seems best explained by cultural-historical factors. Isolates show no such pattern and are more vari...
Geographic distribution of consanguinity in Europe. Average consanguinity (alpha) of 20 large regional or national samples derived from Roman Catholic Dispensations or state archives shows a strong negative relationship with latitude (r = -0.738; P less than 0.001) which seems best explained by cultural-historical fact...
3,767,309
pubmed23n0125_13910
Mollaret's meningitis: a case with increased circulating natural killer cells.
A patient with longstanding Mollaret's meningitis had an increased number of circulating natural killer cells during an acute attack, as evidenced by 73% large granular lymphocytes and 80% Leu-11a-positive peripheral mononuclear cells. Numbers of large granular lymphocytes and Leu-11a-positive cells returned to normal ...
Mollaret's meningitis: a case with increased circulating natural killer cells. A patient with longstanding Mollaret's meningitis had an increased number of circulating natural killer cells during an acute attack, as evidenced by 73% large granular lymphocytes and 80% Leu-11a-positive peripheral mononuclear cells. Numbe...
3,767,320
pubmed23n0125_13911
Palmar dermatoglyphics of the Faroe Islanders.
The palmar dermatoglyphics of 298 male and 331 female Faroe Islanders were studied by the topological method of Penrose and Loesch. The frequency of individual pattern elements, triradii, main-line index and a-b ridge counts were recorded and compared with similar results for Danes and Cornish obtained from the analysi...
Palmar dermatoglyphics of the Faroe Islanders. The palmar dermatoglyphics of 298 male and 331 female Faroe Islanders were studied by the topological method of Penrose and Loesch. The frequency of individual pattern elements, triradii, main-line index and a-b ridge counts were recorded and compared with similar results ...
3,767,312
pubmed23n0125_13912
Bilateral lucency of the globus pallidus complicating methylmalonic acidemia.
A child was seen because of encephalopathy and metabolic ketoacidosis at 19 months. She was found to have a cobalamin-responsive form of methylmalonic acidemia of the cbl A complementation group. However, after treatment with cyanocobalamin and a protein-restricted diet, with recovery from the encephalopathy, she was f...
Bilateral lucency of the globus pallidus complicating methylmalonic acidemia. A child was seen because of encephalopathy and metabolic ketoacidosis at 19 months. She was found to have a cobalamin-responsive form of methylmalonic acidemia of the cbl A complementation group. However, after treatment with cyanocobalamin a...
3,767,321
pubmed23n0125_13913
Atypical presentation and neuropathological studies in 3-hydroxy-3-methylglutaryl-CoA lyase deficiency.
A 6 1/2-month-old male offspring of consanguineous Egyptian parents was first seen because of fever, somnolence, vomiting, right focal motor seizures, right hemiparesis, elevated transaminase levels, hyperammonemia, and acidosis. A computed tomographic scan of the head suggested swelling of the left cerebral hemisphere...
Atypical presentation and neuropathological studies in 3-hydroxy-3-methylglutaryl-CoA lyase deficiency. A 6 1/2-month-old male offspring of consanguineous Egyptian parents was first seen because of fever, somnolence, vomiting, right focal motor seizures, right hemiparesis, elevated transaminase levels, hyperammonemia, ...
3,767,322
pubmed23n0125_13914
[Effect of various forms of inorganic nitrogen on the biosynthesis of rifamycin B].
To study the influence of various forms of inorganic nitrogen on biosynthesis of rifamycin B, ammonium sulfate, ammonium nitrate, ammonium chloride and sodium nitrate were compared. It was shown possible to use mineral salts containing nitrogen in reduced or oxidized form as fermentation medium components. Sodium nitra...
[Effect of various forms of inorganic nitrogen on the biosynthesis of rifamycin B]. To study the influence of various forms of inorganic nitrogen on biosynthesis of rifamycin B, ammonium sulfate, ammonium nitrate, ammonium chloride and sodium nitrate were compared. It was shown possible to use mineral salts containing ...
3,767,329
pubmed23n0125_13915
[Oxidation-reduction status of the culture medium during the biosynthesis of amphotericin B].
The possibility of potentiometric estimation of the oxidation-reduction state of the fermentation broth during production of amphotericin B was studied. It was shown that the reduction capacity of the fermentation broth was high and did not change significantly during the antibiotic biosynthesis. It contained electroch...
[Oxidation-reduction status of the culture medium during the biosynthesis of amphotericin B]. The possibility of potentiometric estimation of the oxidation-reduction state of the fermentation broth during production of amphotericin B was studied. It was shown that the reduction capacity of the fermentation broth was hi...
3,767,330