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PMC9427382
Genotyping and drug resistance patterns of Mycobacterium tuberculosis strains observed in a tuberculosis high-burden municipality in Northeast, Brazil
[ "Cristiane Cunha Frota", "Rosa Maria Salani Mota", "Max Victor Carioca Freitas", "Cynthia Romariz Duarte", "Ligia Regina Franco Sansigolo Kerr", "Elizabeth Clara Barroso", "Phillip Suffys", "Roberta dos Santos Silva Luiz" ]
This study has used a combination of clinical information, spoligotyping, and georeferencing system to elucidate the genetic diversity of the Mycobacterium tuberculosis isolates circulating in a TB-prevalent municipality of Northeast Brazil. A total of 115 M. tuberculosis strains were isolated from pulmonary tuberculos...
10.1016/j.bjid.2012.10.019
[ "Spoligotyping", "Georeferencing", "Drug-resistant tuberculosis", "Tuberculosis" ]
[{"citation_id": "bib0005", "related_text": ["Drug-resistant Mycobacterium tuberculosis (R-TB) is widespread in the world, and of particular concern is the occurrence of multidrug-resistant tuberculosis (MDR-TB), defined as resistance to at least isoniazid (INH) and rifampicin (RIF).1 Resistance may result either from ...
{"introduction": "Drug-resistant Mycobacterium tuberculosis (R-TB) is widespread in the world, and of particular concern is the occurrence of multidrug-resistant tuberculosis (MDR-TB), defined as resistance to at least isoniazid (INH) and rifampicin (RIF).1 Resistance may result either from a selection of drug-resistan...
[{"id": "", "caption": "Map of the municipality of Fortaleza showing the 105 M. tuberculosis isolates included in the study by residential location, 2007–2008. +, resistant TB isolates; (●) sensitive TB isolates; (□) squares with letters (A–K) represent TB patients located either in the same residence or in a close nei...
[{"caption": "Distribution of spoligotyping patterns of 115 tuberculosis cases.", "content": "<table frame=\"hsides\" rules=\"groups\"><thead><tr><th align=\"left\">Family lineage<xref rid=\"tblfn0040\" ref-type=\"table-fn\">a</xref></th><th align=\"center\">No. of isolates<break />115 (%)</th><th align=\"center\">R-TB...
PMC9580340
Structural basis for potent antibody neutralization of SARS-CoV-2 variants including B.1.1.529
[ "Peter D. Kwong", "Nancy J. Sullivan", "John R. Mascola", "Barney S. Graham", "Yaroslav Tsybovsky", "Baoshan Zhang", "Tyler Stephens", "Erik-Stephane D. Stancofski", "Tracy Liu", "Kwanyee Leung", "Claudia Jenkins", "Adrian Creanga", "I-Ting Teng", "Wei Shi", "Misook Choe", "Man Chen", ...
The rapid spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) B.1.1.529 (Omicron) variant and its resistance to neutralization by vaccinee and convalescent sera are driving a search for monoclonal antibodies with potent neutralization. To provide insight into effective neutralization, we determin...
10.1126/science.abn8897
[]
[{"citation_id": "R1", "related_text": ["Since first appearing in late 2019 (1), severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected more than 490 million people and resulted in more than 5.9 million deaths (2). The appearance and rapid spread of the B.1.1.529 (Omicron; BA.1) variant (3, 4)—with 3...
{"cryo-em structure of b.1.1.529 (omicron) spike": "To provide insight into the impact of B.1.1.529 mutations on spike, we expressed and produced the two proline-stabilized (S2P) (6) B.1.1.529 spike and collected single-particle cryo–electron microscopy (cryo-EM) data that resulted in a structure of the trimeric ectodo...
[{"id": "", "caption": "(A) Lentiviruses pseudotyped with SARS-CoV-2 B.1.1.529 spike were incubated with serial dilutions of the indicated combination of antibodies, and IC50 and IC80 values were determined. Ranges are indicated with white (>10,000 ng/ml), light blue (>1000 to ≤10,000 ng/ml), yellow (>100 to ≤1000 ng/m...
[]
PMC9584045
Lessons from COVID-19 mortality data across countries
[ "Gian Carlo Blangiardo", "Federico Rea", "Giovanni Corrao" ]
Several online sources provide up-to-date open-access data on numbers, rates and proportions of COVID-19 deaths. Our article aims of comparing and interpreting between-country trends of mortality rate, case-fatality and all-cause excess mortality. We used data from open databases (Our World in Data mostly) for comparin...
10.1097/HJH.0000000000002833
[ "surveillance", "mortality", "covid-19", "case fatality" ]
[{"citation_id": "R1", "related_text": ["There is much debate around the current availability of COVID-19 mortality data from several sources worldwide [1]. This debate is not new. What is new is the speed with which several organization have reacted to the crisis by making available data immediately accessible. Online...
{"introduction": "There is much debate around the current availability of COVID-19 mortality data from several sources worldwide [1]. This debate is not new. What is new is the speed with which several organization have reacted to the crisis by making available data immediately accessible. Online sources such as those ...
[{"id": "", "caption": "Weekly trends in all-cause excess mortality in eleven European and North American countries during the first 48 weeks of 2020. The Human Mortality Database (https://www.mortality.org/).", "related_text": "Figure 2 shows the entire historical series of all-cause excess mortality during the first ...
[{"caption": "Summarized mortality measures of selected countries", "content": "<table frame=\"hsides\" rules=\"groups\" border=\"0\"><thead><tr><td align=\"left\" rowspan=\"1\" colspan=\"1\">Country</td><td align=\"center\" rowspan=\"1\" colspan=\"1\">COVID-19 raw mortality rate<sup>a</sup> (per 1 000 000 person-year)...
PMC9728410
Current Status of Epidemiology, Diagnosis, Therapeutics, and Vaccines for Novel Coronavirus Disease 2019 (COVID-19)
[ "Seong-Jun Kim", "Bum-Tae Kim", "Jinjong Myoung", "Hae-Soo Kim", "Sunhee Lee", "Mi-Hwa Kim", "Hye-Jin Shin", "Dae-Gyun Ahn" ]
Coronavirus disease 2019 (COVID-19), which causes serious respiratory illness such as pneumonia and lung failure, was first reported in Wuhan, the capital of Hubei, China. The etiological agent of COVID-19 has been confirmed as a novel coronavirus, now known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-...
10.4014/jmb.2003.03011
[ "outbreak", "coronavirus", "SARS-CoV-2", "COVID-19", "2019-nCoV" ]
[{"citation_id": "ref1", "related_text": ["In December 2019, cases of serious illness causing pneumonia and death were first reported in Wuhan, the capital of Hubei, China. Soon after, the number of cases soared dramatically, spreading across China and worldwide. As of March 25, more than 400,000 cases of the disease h...
{"introduction": "In December 2019, cases of serious illness causing pneumonia and death were first reported in Wuhan, the capital of Hubei, China. Soon after, the number of cases soared dramatically, spreading across China and worldwide. As of March 25, more than 400,000 cases of the disease have been confirmed with o...
[]
[]
PMC9754790
Association of Symptoms of Attention Deficit and Hyperactivity with Problematic Internet Use among University Students in Wuhan, China During the COVID-19 Pandemic
[ "Jie Shi", "Yanping Bao", "Lin Lu", "Guofu Huang", "Yu Lu", "John Strang", "Thomas R Kosten", "Maosheng Ran", "Li Yang", "Siwei Sun", "Kai Yuan", "Wei Yan", "Shiqiu Meng", "Jiahui Deng", "Yankun Sun", "Yan Sun", "Jianyu Que", "Le Shi", "Sizhen Su", "Lin Liu", "Yingying Xu", ...
COVID-19 is still spreading worldwide and posing a threat to individuals’ physical and mental health including problematic internet use (PIU). A potentially high-risk group for PIU are those with symptoms of attention deficit and hyperactivity (ADHD symptoms), because of restrictions in their physical activity levels a...
10.1016/j.jad.2021.02.078
[ "University students", "Symptoms of attention deficit and hyperactivity", "Problematic internet use", "COVID-19" ]
[{"citation_id": "bib0001", "related_text": ["Up to now, coronavirus disease 2019 (COVID-19), initially detected in December, 2019, has been in control in some countries, whereas in other many countries and regions the pandemic still prolongs and represents a great threat to individuals’ as well as societal physical an...
{"introduction": "Up to now, coronavirus disease 2019 (COVID-19), initially detected in December, 2019, has been in control in some countries, whereas in other many countries and regions the pandemic still prolongs and represents a great threat to individuals’ as well as societal physical and mental health (Bao et al.,...
[]
[{"caption": "Multiple Linear Regression Analyses of the Association between Symptoms of Attention Deficit and Hyperactivity, Other Mental Illness Symptoms and Problematic Internet Use.", "content": "<table frame=\"hsides\" rules=\"groups\"><thead><tr><th align=\"left\" rowspan=\"2\" valign=\"top\">Variables</th><th co...
PMC9758590
COVID-19 and food security: Panel data evidence from Nigeria
[ "Jordan Chamberlin", "Luca Tiberti", "Kibrom A. Abay", "Mulubrhan Amare" ]
This paper combines pre-pandemic face-to-face survey data with follow up phone surveys collected in April-May 2020 to examine the implication of the COVID-19 pandemic on household food security and labor market participation outcomes in Nigeria. To examine these relationships and implications, we exploit spatial variat...
10.1016/j.foodpol.2021.102099
[ "Sub-Saharan Africa", "Labor market participation", "Welfare", "Pandemic", "Coronavirus", "COVID-19" ]
[{"citation_id": "b0005", "related_text": [], "reference_info": "AbayK.A.AbateG.A.BarrettC.B.BernardT.Correlated non-classical measurement errors and ‘Second Best’ policy inference: The case of the inverse size-productivity relationship in agricultureJ. Dev. Econ.1392019171184", "reference_doi": null}, {"citation_id": ...
{"introduction": "The COVID-19 pandemic is ravishing local, national, and global economies. In addition to the direct health impacts, the pandemic is having widespread effects on employment, poverty, food security, nutrition, education and health, and the overall functioning of food systems (Barrett, 2020, Devereux et ...
[{"id": "", "caption": "Confirmed COVID-19 cases and Lockdown restrictions by states.", "related_text": "The average state-level COVID-19 cases (at the end of May) is 222, and 46 percent of the states have imposed lockdown restrictions in the period March 28 through May 15. Fig. 2 presents the geographic distribution o...
[{"caption": "COVID-19 cases, governmental responses, and household food security outcomes, with livelihood orientation category interactions.", "content": "<table frame=\"hsides\" rules=\"groups\"><thead><tr><th colspan=\"5\">Panel A: COVID-19 cases and household food security outcomes<hr /></th></tr><tr><th /><th>(1)...
PMC9799368
Indirect protection of children from SARS-CoV-2 infection through parental vaccination
[ "Noam Barda", "Ran D. Balicer", "Ben Y. Reis", "Marc Lipsitch", "Daniel Nevo", "Noa Dagan", "Eldad Kepten", "Yatir Ben-Shlomo", "Galit Shaham", "Samah Hayek" ]
Children not vaccinated against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may still benefit from vaccines through protection from vaccinated contacts. We estimated the protection provided to children through parental vaccination with the BNT162b2 vaccine. We studied households without prior infection...
10.1126/science.abm3087
[]
[{"citation_id": "R1", "related_text": ["Since December 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread globally (1), resulting in more than 200 million confirmed infections and more than 4 million deaths (2). COVID-19 vaccines serve a critical role in combating the spread of the pandemic....
{}
[{"id": "", "caption": "An illustration showing the indirect effect of parental vaccination on children’s risk of SARS-CoV-2 infection and two of its composite parts: the direct effect of vaccination on the parents (estimated as the incidence rate ratio of parental infection between vaccinated and unvaccinated parents)...
[{"caption": "The secondary attack rate (SAR) from an infected parent to susceptible children in the household by parent vaccination status. The unit of observation for this analysis consisted of households in which a parent (the index parent) was infected with SARS-CoV-2. The exposure was the vaccination status of the...
PMC9808181
Understanding the Prevalence and Associated Factors of Behavioral Intention of COVID-19 Vaccination Under Specific Scenarios Combining Effectiveness, Safety, and Cost in the Hong Kong Chinese General Population
[ "Paul K.S. Chan", "Martin C.S. Wong", "Mason M.C. Lau", "Joseph T.F. Lau", "Yanqiu Yu" ]
Background: The prevalence of coronavirus disease 2019 (COVID-19) vaccination is very critical in controlling COVID-19. This study mainly aimed to (1) investigate behavioral intentions of COVID-19 vaccination under various specific scenarios, and (2) associated factors of the afore-mentioned vaccination intentions. Met...
10.34172/ijhpm.2021.02
[ "Hong Kong", "Cost", "Safety", "Effectiveness", "Behavioral Intention", "COVID-19 Vaccination" ]
[{"citation_id": "R1", "related_text": ["The coronavirus disease 2019 (COVID-19) has globally accumulated 35 347 404 cases and 1 039 406 deaths (6/10/2020).1 Recently, the pandemic has resurged in many countries. In most countries, the current measures seem inadequate in halting the pandemic, which has comprehensively ...
{"introduction": "The coronavirus disease 2019 (COVID-19) has globally accumulated 35 347 404 cases and 1 039 406 deaths (6/10/2020).1 Recently, the pandemic has resurged in many countries. In most countries, the current measures seem inadequate in halting the pandemic, which has comprehensively damaged people’s lives ...
[{"id": "", "caption": "", "related_text": "In Figure 2a, males expressed higher BICV than females in two of the five 80% effectiveness scenarios that involved a HK$ 500 cost (S2, S4) and all the four 50% effectiveness scenarios (S5-S8) (ORc ranged from 1.76 to 4.06, P< .05). In Figure 2b, the oldest group showed signi...
[{"caption": "", "content": "<table frame=\"hsides\" rules=\"none\"><tbody><tr><td rowspan=\"2\" style=\"text-align:left;vertical-align:middle;border-width:0.5pt 0pt 0pt 0pt;border-style: solid none none none;\" colspan=\"1\">\n<bold>Variables</bold>\n</td><td style=\"text-align:left;vertical-align:middle;border-width:...
PMC9906135
Thrombocytopenia and its association with mortality in patients with COVID‐19
[ "You Shang", "Yuan Yu", "Jiqian Xu", "Yongran Wu", "Yaxin Wang", "Qingyu Yang", "Xiaobo Yang" ]
Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), which causes novel coronavirus disease 2019 (COVID‐19), is spreading rapidly around the world. Thrombocytopenia in patients with COVID‐19 has not been fully studied. To describe thrombocytopenia in patients with COVID‐19. For each of 1476 consecutive patient...
10.1111/jth.14848
[ "thrombocytopenia", "SARS‐CoV‐2", "mortality", "generalized linear model", "COVID‐19" ]
[{"citation_id": "bb0010", "related_text": ["Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), a new highly transmittable coronavirus, is spreading rapidly around the world.1 The virus causes a spectrum of diseases, named novel coronavirus disease 2019 (COVID‐19) by the World Health Organization (WHO).2 Amo...
{"essentials": "•Thrombocytopenia in patients with novel coronavirus disease 2019 (COVID‐19) needs further study.•A retrospective single‐centered study including 1476 patients was conducted.•Thrombocytopenia is common in patients with COVID‐19.•Thrombocytopenia is associated with increased risk of in‐hospital mortality...
[{"id": "", "caption": "Number of patients and mortalities in four groups of patients with COVID‐19 based on their nadir platelet counts", "related_text": "A total of 1476 patients, comprising 1238 (83.9%) survivors and 238 (16.1%) non‐survivors, was included. Their median [IQR] age was 57 [47‐67] years and 776 (52.6%)...
[{"caption": "Relative risk of death in age, gender, and groups of nadir platelet count in patients with COVID‐19 obtained using a generalized linear model", "content": "<table frame=\"hsides\" rules=\"groups\"><thead><tr><th align=\"left\" /><th align=\"left\">Relative risk (95% confidence interval)</th><th align=\"le...
PMC9978672
Severity of maternal infection and perinatal outcomes during periods of SARS-CoV-2 wildtype, alpha, and delta variant dominance in the UK: prospective cohort study
[ "Marian Knight", "Jennifer J Kurinczuk", "Peter Brocklehurst", "Maria Quigley", "Patrick O'Brien", "Christopher Gale", "Nigel A B Simpson", "Eddie Morris", "Kathryn Bunch", "Rema Ramakrishnan", "Nicola Vousden" ]
To compare the severity of maternal infection and perinatal outcomes during periods in which wildtype, alpha variant, and delta variant of SARS-CoV-2 were dominant in the UK. Prospective cohort study. 194 obstetric units across the UK, during the following periods: between 1 March and 30 November 2020 (wildtype dominan...
10.1136/bmjmed-2021-000053
[ "neonatology", "pregnancy complications", "COVID-19" ]
[{"citation_id": "R1", "related_text": ["In 2020, the World Health Organization's living systematic review concluded that SARS-CoV-2 infection during pregnancy was associated with an increased risk of admission to intensive care for mothers, preterm birth, and admission for neonatal care for infants.1 Included studies ...
{"introduction": "In 2020, the World Health Organization's living systematic review concluded that SARS-CoV-2 infection during pregnancy was associated with an increased risk of admission to intensive care for mothers, preterm birth, and admission for neonatal care for infants.1 Included studies predominantly contained...
[{"id": "", "caption": "Admissions of pregnant women with symptoms of confirmed SARS-CoV-2 to UK hospitals during dominance periods of original wildtype (1 March to 30 November 2020), alpha variant (1 December 2020 to 15 May 2021), and delta variant (16 May to 31 October 2021)", "related_text": "In total, 4436 women we...
[{"caption": "Perinatal outcomes for babies of women admitted to UK hospitals with SARS-CoV-2 related symptoms during periods in which the original wildtype, alpha variant, and delta variant were dominant", "content": "<table frame=\"hsides\" rules=\"groups\"><thead><tr><td align=\"left\" valign=\"bottom\" rowspan=\"2\...
PMC9998167
A change of perceived innovativeness for contactless food delivery services using drones after the outbreak of COVID-19
[ "Jinsoo Hwang", "Insin Kim", "Jinkyung Jenny Kim" ]
This study aims to identify how behavioral intentions are formed in the context of drone food delivery services using the moderating role before and after the outbreak of COVID-19. A conceptual model including eight hypotheses was developed and tested based on the data of two consumer samples, one collected before and ...
10.1016/j.ijhm.2020.102758
[ "Theory of planned behavior", "Perceived innovativeness", "Contactless services", "COVID-19", "Drone food delivery services" ]
[{"citation_id": "bib0005", "related_text": ["The theory of planned behavior (TPB) is a framework that was proposed by Ajzen (1991) for comprehension of consumer behavior. The TPB postulates that the individuals’ behavioral intentions are determined by attitude, the subjective norm, and perceived behavioral control (Aj...
{"introduction": "The world has witnessed the advent of various innovative technologies. In particular, drones open up infinite possibilities in the industry of food delivery services (Bamburry, 2015; Hwang et al., 2019). Moreover, drones are regarded as an innovative solution to the drawbacks of the existing food deli...
[{"id": "", "caption": "Standardized theoretical path coefficients.", "related_text": "The proposed model was tested using structural equation modeling analysis. The overall evaluation of the model fit revealed a satisfactory fit of the model to the data (χ2 = 342.465, df = 86, χ2/df = 3.982, p < .001, NFI = .942, CFI ...
[{"caption": "Moderating role of the outbreak of COVID-19.", "content": "<table frame=\"hsides\" rules=\"groups\"><thead><tr><th align=\"left\">Path</th><th colspan=\"4\" align=\"left\">Unconstrained model<hr /></th><th align=\"left\">Constrained model</th><th align=\"left\">Tests of moderator</th><th align=\"left\" />...