id stringlengths 68 80 | image stringlengths 71 73 | conversations listlengths 2 2 |
|---|---|---|
MorDetail_TCGA-B6-A1KI-01Z-00-DX1.EFAA08A8-02EC-4A9B-AC6B-79BF2DC5A2AA-5 | TCGA-BRCA/TCGA-B6-A1KI-01Z-00-DX1.EFAA08A8-02EC-4A9B-AC6B-79BF2DC5A2AA.pt | [
{
"from": "human",
"value": "<image>\nIs there any sign of vascular invasion present in the tissue?"
},
{
"from": "gpt",
"value": "No, there is no evidence of vascular invasion in the tissue. The tumor cells have not entered any blood vessels or lymphatic channels, suggesting limited potential f... |
Morphology_TCGA-WK-A8XT-01Z-00-DX1.BA738161-33AA-46F9-8204-81C89548C1A8-1 | TCGA-SARC/TCGA-WK-A8XT-01Z-00-DX1.BA738161-33AA-46F9-8204-81C89548C1A8.pt | [
{
"from": "human",
"value": "<image>\nCan you describe the pattern of tumor infiltration?"
},
{
"from": "gpt",
"value": "The tumor infiltration is characterized by focal lymphovascular invasion, where spindle-shaped tumor cells are penetrating into vascular structures. This suggests some degree ... |
MorDetail_TCGA-A1-A0SB-01Z-00-DX1.B34C267B-CAAA-4AB6-AD5C-276C26F997A1-2 | TCGA-BRCA/TCGA-A1-A0SB-01Z-00-DX1.B34C267B-CAAA-4AB6-AD5C-276C26F997A1.pt | [
{
"from": "human",
"value": "<image>\nAre the nuclei of the tumor cells showing moderate variability in size and shape?"
},
{
"from": "gpt",
"value": "Yes, the nuclei display moderate variability in size and shape, consistent with an intermediate nuclear grade. The nuclei appear somewhat irregul... |
Morphology_choice_TCGA-B0-4703-01Z-00-DX1.05400469-03bd-4f1b-ac33-580a8b582c39-3 | TCGA-KIRC/TCGA-B0-4703-01Z-00-DX1.05400469-03bd-4f1b-ac33-580a8b582c39.pt | [
{
"from": "human",
"value": "<image>\nWhat are the notable features of the cellular morphology in this renal cell carcinoma specimen? A) The nuclei are uniform in appearance, showing no signs of active division. B) Nuclei appear small and regular with minimal pleomorphism. C) The tumor nuclei are markedly e... |
Conversation_TCGA-A6-3807-01Z-00-DX1.c3de2064-4f8d-4786-9ff9-2e0f44293717-1 | TCGA-COAD/TCGA-A6-3807-01Z-00-DX1.c3de2064-4f8d-4786-9ff9-2e0f44293717.pt | [
{
"from": "human",
"value": "<image>\nCan you provide an overall description of the whole slide image?"
},
{
"from": "gpt",
"value": "The slide reveals features of adenocarcinoma with glandular structures that diverge moderately from the normal architecture of the colonic epithelium. These neopl... |
Diagnosis_choice_TCGA-49-AARQ-01Z-00-DX1.3FA36419-1658-4602-9170-84A622787C3E-1 | TCGA-LUAD/TCGA-49-AARQ-01Z-00-DX1.3FA36419-1658-4602-9170-84A622787C3E.pt | [
{
"from": "human",
"value": "<image>\nBased on the observed features, what do you think is the correct histological classification of the tumor? A) Squamous cell carcinoma B) Small cell lung carcinoma C) Moderately differentiated adenocarcinoma D) Large cell carcinoma"
},
{
"from": "gpt",
"value... |
Conversation_TCGA-AR-A1AJ-01Z-00-DX1.34B9FCF0-74D8-4328-9B5A-698AD57EDA85-3 | TCGA-BRCA/TCGA-AR-A1AJ-01Z-00-DX1.34B9FCF0-74D8-4328-9B5A-698AD57EDA85.pt | [
{
"from": "human",
"value": "<image>\nHow would you histologically classify the tumor based on your examination of the slide?"
},
{
"from": "gpt",
"value": "The histological classification is invasive ductal carcinoma. This conclusion is drawn from the observed infiltrative growth pattern of duc... |
Conversation_TCGA-D8-A1XY-01Z-00-DX2.33D96E5C-5291-4864-B282-8BACA2043586-2 | TCGA-BRCA/TCGA-D8-A1XY-01Z-00-DX2.33D96E5C-5291-4864-B282-8BACA2043586.pt | [
{
"from": "human",
"value": "<image>\nWhich features observed in the slide are most crucial for diagnosis?"
},
{
"from": "gpt",
"value": "The most critical features observed include the irregular clusters of malignant epithelial cells and their moderate formation of glandular structures, signify... |
MorDetail_TCGA-CQ-7069-01Z-00-DX1.227CEB7F-4265-42F5-B313-DB07484B51A8-3 | TCGA-HNSC/TCGA-CQ-7069-01Z-00-DX1.227CEB7F-4265-42F5-B313-DB07484B51A8.pt | [
{
"from": "human",
"value": "<image>\nIs there any presence of necrosis in the tissue sample?"
},
{
"from": "gpt",
"value": "No, necrosis is not observed within this tissue sample. The examined sections do not display any areas of cell death, and the tumor appears viable throughout with no necro... |
MorDetail_TCGA-X7-A8DD-01Z-00-DX1.61B656BB-BFFC-4422-AE6D-2AE3B082CD7B-4 | TCGA-THYM/TCGA-X7-A8DD-01Z-00-DX1.61B656BB-BFFC-4422-AE6D-2AE3B082CD7B.pt | [
{
"from": "human",
"value": "<image>\nWhat are the characteristics of the serum lakes observed in the tissue?"
},
{
"from": "gpt",
"value": "The serum lakes are areas of hypocellularity that contain proteinaceous fluid. They are irregularly shaped, scattered within the tumor matrix, and appear a... |
Conversation_TCGA-W5-AA2G-01Z-00-DX1.DA30CC19-6DDF-4A23-8FC6-D800155FAAC5-4 | TCGA-CHOL/TCGA-W5-AA2G-01Z-00-DX1.DA30CC19-6DDF-4A23-8FC6-D800155FAAC5.pt | [
{
"from": "human",
"value": "<image>\nWhat is the grading of this cholangiocarcinoma based on the observed features?"
},
{
"from": "gpt",
"value": "The tumor is classified as Grade 3 cholangiocarcinoma. This grading reflects the poorly differentiated nature of the neoplastic cells, marked nuclea... |
MorDetail_TCGA-RW-A686-01Z-00-DX2.7308B621-13B0-4FCA-BC5C-2AA2C082F433-3 | TCGA-PCPG/TCGA-RW-A686-01Z-00-DX2.7308B621-13B0-4FCA-BC5C-2AA2C082F433.pt | [
{
"from": "human",
"value": "<image>\nIs there evidence of hemorrhage or necrosis within the tumor?"
},
{
"from": "gpt",
"value": "While not explicitly described in detail, the presence of hemorrhage or necrosis is suggested in the context provided. The slide may display localized areas where ce... |
Conversation_TCGA-90-A59Q-01Z-00-DX1.9F4ABA20-E9F7-4524-874E-E8C42D84AFFE-1 | TCGA-LUSC/TCGA-90-A59Q-01Z-00-DX1.9F4ABA20-E9F7-4524-874E-E8C42D84AFFE.pt | [
{
"from": "human",
"value": "<image>\nCan you provide an overall description of the whole slide image?"
},
{
"from": "gpt",
"value": "The whole slide image exhibits an ill-defined mass predominantly composed of atypical squamous epithelial cells. These cells display significant pleomorphism, wit... |
MorDetail_TCGA-AJ-A3NC-01Z-00-DX1.A31856AC-EDD5-4955-BFED-08C162A1C143-2 | TCGA-UCEC/TCGA-AJ-A3NC-01Z-00-DX1.A31856AC-EDD5-4955-BFED-08C162A1C143.pt | [
{
"from": "human",
"value": "<image>\nAre there focal areas of clear cells within the adenocarcinoma?"
},
{
"from": "gpt",
"value": "Yes, there are focal areas where the tumor cells contain abundant clear cytoplasm, giving the cells a distinct appearance. These clear cells are interspersed among... |
Diagnosis_choice_TCGA-CG-5727-01Z-00-DX1.2B805B2B-6D29-4F6F-B22E-944091C53127-1 | TCGA-STAD/TCGA-CG-5727-01Z-00-DX1.2B805B2B-6D29-4F6F-B22E-944091C53127.pt | [
{
"from": "human",
"value": "<image>\nBased on the observed features, what do you think is the correct histological classification of the tumor? A) Diffuse type gastric carcinoma B) Adenocarcinoma of the stomach C) Gastric lymphoma D) Intestinal type gastric carcinoma"
},
{
"from": "gpt",
"value... |
Report_TCGA-55-8511-01Z-00-DX1.8EDFB05B-5B59-46EA-973C-1048B1E284D2-1 | TCGA-LUAD/TCGA-55-8511-01Z-00-DX1.8EDFB05B-5B59-46EA-973C-1048B1E284D2.pt | [
{
"from": "human",
"value": "<image>\nWhat morphological features and diagnostic conclusions can be derived from the whole slide histopathology image?"
},
{
"from": "gpt",
"value": "Microscopic observation of the pathology slide reveals the presence of irregular clusters of malignant epithelial ... |
Report_TCGA-23-1121-01Z-00-DX1.E2F25441-32C3-46BF-A845-CB4FA787E8CB-1 | TCGA-OV/TCGA-23-1121-01Z-00-DX1.E2F25441-32C3-46BF-A845-CB4FA787E8CB.pt | [
{
"from": "human",
"value": "<image>\nWhat are the key features and diagnostic information that can be derived from the whole slide histopathology image?"
},
{
"from": "gpt",
"value": "Microscopic observation of the pathology slide reveals high-grade carcinoma with serous characteristics. Necros... |
Morphology_choice_TCGA-PK-A5HB-01Z-00-DX1.B51AC518-872A-462B-B4AB-EA2876CB5FAF-3 | TCGA-ACC/TCGA-PK-A5HB-01Z-00-DX1.B51AC518-872A-462B-B4AB-EA2876CB5FAF.pt | [
{
"from": "human",
"value": "<image>\nWhat are the notable features of the cellular morphology in this slide? A) The cells show minimal variability in size and shape, with low mitotic activity. B) The cells are uniform in appearance, with consistent nuclear size and shape. C) The cells display marked nuclea... |
MorDetail_TCGA-VM-A8CA-01Z-00-DX3.DF5FF5C7-CCF8-41BD-9FF5-3D1185E350B8-1 | TCGA-LGG/TCGA-VM-A8CA-01Z-00-DX3.DF5FF5C7-CCF8-41BD-9FF5-3D1185E350B8.pt | [
{
"from": "human",
"value": "<image>\nAre calcifications present within the tumor matrix?"
},
{
"from": "gpt",
"value": "Yes, calcifications are present within the tumor matrix, appearing as small, granular deposits. These calcified foci are distributed throughout the tissue and contribute to th... |
Morphology_TCGA-TM-A84H-01Z-00-DX2.3DD9940B-E941-45C4-8C26-0F87E8EF4569-1 | TCGA-LGG/TCGA-TM-A84H-01Z-00-DX2.3DD9940B-E941-45C4-8C26-0F87E8EF4569.pt | [
{
"from": "human",
"value": "<image>\nWhat observations can you make about the tissue architecture on this slide?"
},
{
"from": "gpt",
"value": "The tissue architecture displays a range from sparsely cellular microcystic areas to more densely packed nodular regions. The microcystic zones contain... |
MorDetail_TCGA-EW-A2FR-01Z-00-DX1.FF521BBF-F5BA-4B03-9CA1-101A337F4B45-1 | TCGA-BRCA/TCGA-EW-A2FR-01Z-00-DX1.FF521BBF-F5BA-4B03-9CA1-101A337F4B45.pt | [
{
"from": "human",
"value": "<image>\nDo the epithelial cells infiltrate the surrounding stromal tissue or exhibit invasiveness?"
},
{
"from": "gpt",
"value": "Yes, the epithelial cells are infiltrating the surrounding stromal tissue, demonstrating invasive characteristics. They have spread beyo... |
Conversation_TCGA-D8-A1Y0-01Z-00-DX1.10F40197-4174-43CC-AAD3-8CB85154FB2D-1 | TCGA-BRCA/TCGA-D8-A1Y0-01Z-00-DX1.10F40197-4174-43CC-AAD3-8CB85154FB2D.pt | [
{
"from": "human",
"value": "<image>\nCan you provide an overall description of the whole slide image (WSI)?"
},
{
"from": "gpt",
"value": "The slide reveals a significant infiltration of epithelial cells into the surrounding stroma, disrupting the normal tissue architecture. This is coupled wit... |
Report_TCGA-DK-A3WW-01Z-00-DX1.4C3751B5-BD3E-4902-A092-B5877B67851F-1 | TCGA-BLCA/TCGA-DK-A3WW-01Z-00-DX1.4C3751B5-BD3E-4902-A092-B5877B67851F.pt | [
{
"from": "human",
"value": "<image>\nWhat are the key features and diagnostic information that can be derived from the whole slide histopathology image?"
},
{
"from": "gpt",
"value": "Microscopic observation of the pathology slide reveals urothelial carcinoma with mixed histologic features, inc... |
Conversation_TCGA-FY-A3W9-01Z-00-DX1.14465C4E-0D39-4742-91B8-FEB6F5B11807-2 | TCGA-THCA/TCGA-FY-A3W9-01Z-00-DX1.14465C4E-0D39-4742-91B8-FEB6F5B11807.pt | [
{
"from": "human",
"value": "<image>\nWhich observed features are most significant for making a diagnosis?"
},
{
"from": "gpt",
"value": "Key features include the presence of multiple adenomatous nodules with hyperplastic and variably sized follicles. The absence of significant atypia or increas... |
Morphology_choice_TCGA-IG-A3YA-01Z-00-DX1.C2A7B316-44E0-4CA3-B76A-241C61BFE492-3 | TCGA-ESCA/TCGA-IG-A3YA-01Z-00-DX1.C2A7B316-44E0-4CA3-B76A-241C61BFE492.pt | [
{
"from": "human",
"value": "<image>\nWhat are the notable features of the cellular morphology in this slide of squamous cell carcinoma? A) Nuclei are uniform, with very low pleomorphism and no mitotic figures. B) There is significant nuclear pleomorphism, with irregular shapes and high mitotic activity. C)... |
Report_TCGA-2Z-A9JG-01Z-00-DX1.1ACF5371-F7F7-4477-9450-4A46709CCEDC-1 | TCGA-KIRP/TCGA-2Z-A9JG-01Z-00-DX1.1ACF5371-F7F7-4477-9450-4A46709CCEDC.pt | [
{
"from": "human",
"value": "<image>\nHow would you summarize the morphological features and diagnosis in the whole slide histopathology image?"
},
{
"from": "gpt",
"value": "Microscopic observation of the pathology slide reveals a renal epithelial neoplasm characterized by a papillary growth pa... |
MorDetail_TCGA-ED-A7PX-01Z-00-DX1.D75A1B1F-7062-44D6-8BF0-B511BAF8E45B-5 | TCGA-LIHC/TCGA-ED-A7PX-01Z-00-DX1.D75A1B1F-7062-44D6-8BF0-B511BAF8E45B.pt | [
{
"from": "human",
"value": "<image>\nWhat are the characteristics of the cytoplasm in the tumor cells?"
},
{
"from": "gpt",
"value": "The cytoplasm of the tumor cells is moderately abundant, displaying either basophilic or vacuolated characteristics. This variation contributes to the polygonal ... |
Conversation_TCGA-HT-7695-01Z-00-DX2.4F0E4092-5F35-4689-AD3D-C5402BAB0F60-1 | TCGA-LGG/TCGA-HT-7695-01Z-00-DX2.4F0E4092-5F35-4689-AD3D-C5402BAB0F60.pt | [
{
"from": "human",
"value": "<image>\nCan you provide an overall description of the whole slide image?"
},
{
"from": "gpt",
"value": "The slide reveals a moderately hypercellular glial neoplasm that extensively infiltrates both the gray and white matter. Within the gray matter, there is a signif... |
Morphology_choice_TCGA-97-A4M3-01Z-00-DX1.16330A66-2501-48D2-AF6A-713698BF6918-1 | TCGA-LUAD/TCGA-97-A4M3-01Z-00-DX1.16330A66-2501-48D2-AF6A-713698BF6918.pt | [
{
"from": "human",
"value": "<image>\nWhat can you observe about the tissue architecture in this well-differentiated adenocarcinoma specimen? A) The tumor shows poorly differentiated structures, with no preservation of normal architectural features. B) The tumor exhibits a mixture of histological patterns, ... |
Conversation_TCGA-77-A5G7-01Z-00-DX1.F1FECF5D-C940-43D0-B49B-66C95AD9C85A-3 | TCGA-LUSC/TCGA-77-A5G7-01Z-00-DX1.F1FECF5D-C940-43D0-B49B-66C95AD9C85A.pt | [
{
"from": "human",
"value": "<image>\nBased on the observed features, what is the histological classification?"
},
{
"from": "gpt",
"value": "The histological classification based on the observed features is squamous cell carcinoma. This classification is supported by the presence of moderately ... |
Morphology_choice_TCGA-XK-AAK1-01Z-00-DX1.5354527B-905C-4F39-B469-3A64D0BC56A2-1 | TCGA-PRAD/TCGA-XK-AAK1-01Z-00-DX1.5354527B-905C-4F39-B469-3A64D0BC56A2.pt | [
{
"from": "human",
"value": "<image>\nWhat pattern of tumor infiltration is noted in this prostatic adenocarcinoma specimen? A) Tumor cells infiltrate with perineural invasion. B) Tumor cells infiltrate surrounding stroma without perineural or vascular invasion. C) Tumor cells show extensive vascular involv... |
Conversation_TCGA-ED-A7PZ-01Z-00-DX1.CD9C0D80-4E6C-40EF-BF56-54BD7EFDBDC1-2 | TCGA-LIHC/TCGA-ED-A7PZ-01Z-00-DX1.CD9C0D80-4E6C-40EF-BF56-54BD7EFDBDC1.pt | [
{
"from": "human",
"value": "<image>\nWhich features observed in this slide are most significant for making a diagnosis?"
},
{
"from": "gpt",
"value": "Key features include the trabecular pattern of tumor cell arrangement, polygonal cell shape, round vesicular nuclei, and prominent nucleoli. The... |
MorDetail_TCGA-BH-A0BF-01Z-00-DX1.934DF984-9054-4B20-B85B-9CF94B8DC3D4-2 | TCGA-BRCA/TCGA-BH-A0BF-01Z-00-DX1.934DF984-9054-4B20-B85B-9CF94B8DC3D4.pt | [
{
"from": "human",
"value": "<image>\nDo the nuclei among the epithelial cells exhibit marked variability in size and shape?"
},
{
"from": "gpt",
"value": "Yes, the nuclei exhibit marked variability in size and shape, indicating significant nuclear pleomorphism. The nuclei are highly irregular, ... |
Morphology_TCGA-AF-A56K-01Z-00-DX1.5870355A-679E-4E4C-8A00-B13C6F2A3FF2-1 | TCGA-READ/TCGA-AF-A56K-01Z-00-DX1.5870355A-679E-4E4C-8A00-B13C6F2A3FF2.pt | [
{
"from": "human",
"value": "<image>\nCan you describe the pattern of tumor infiltration?"
},
{
"from": "gpt",
"value": "The gland-forming epithelial cells are infiltrating through the muscularis propria and into the surrounding pericolonic adipose tissue. The infiltration is characterized by el... |
Treatment_TCGA-E2-A1L7-01Z-00-DX1.BE796CD2-2E81-44E8-8CA2-85B4D2A31B64-1 | TCGA-BRCA/TCGA-E2-A1L7-01Z-00-DX1.BE796CD2-2E81-44E8-8CA2-85B4D2A31B64.pt | [
{
"from": "human",
"value": "<image>\nWhat is the recommended treatment plan for a patient diagnosed with triple-negative invasive ductal carcinoma, Modified SBR Grade 3, TNM staging T2N2M0?"
},
{
"from": "gpt",
"value": "1. Surgery: Start with mastectomy or breast-conserving surgery, depending ... |
Morphology_choice_TCGA-HU-A4G9-01Z-00-DX1.806F4C5A-D2F8-4457-B6F9-99B67105C676-3 | TCGA-STAD/TCGA-HU-A4G9-01Z-00-DX1.806F4C5A-D2F8-4457-B6F9-99B67105C676.pt | [
{
"from": "human",
"value": "<image>\nWhat are the notable features of the cellular morphology in this slide? A) Cells show marked pleomorphism with numerous abnormal mitotic figures. B) Cells exhibit moderate variability in nuclear size and shape. C) Cells are uniform, with regular nuclei and minimal varia... |
Morphology_TCGA-DX-AB2O-01Z-00-DX3.74071C3B-F83E-4E40-9CCF-C5A93BD65407-2 | TCGA-SARC/TCGA-DX-AB2O-01Z-00-DX3.74071C3B-F83E-4E40-9CCF-C5A93BD65407.pt | [
{
"from": "human",
"value": "<image>\nWhat observations can you make about the tissue architecture on this slide?"
},
{
"from": "gpt",
"value": "The tissue architecture is markedly disrupted with irregular, non-cohesive patterns. The spindle cells infiltrate in a haphazard fashion, leading to th... |
Conversation_TCGA-05-4382-01Z-00-DX1.76b49a4c-dbbb-48b0-b677-6d3037e5ce88-3 | TCGA-LUAD/TCGA-05-4382-01Z-00-DX1.76b49a4c-dbbb-48b0-b677-6d3037e5ce88.pt | [
{
"from": "human",
"value": "<image>\nWhat is the histological classification based on your examination of the slide?"
},
{
"from": "gpt",
"value": "The histological classification of this tumor is mixed large-cell and clear-cell adenocarcinoma. This classification is supported by the distinct p... |
MorDetail_TCGA-A2-A25F-01Z-00-DX1.87499CD4-E41C-46B1-AAF3-5CE881F2B8BC-6 | TCGA-BRCA/TCGA-A2-A25F-01Z-00-DX1.87499CD4-E41C-46B1-AAF3-5CE881F2B8BC.pt | [
{
"from": "human",
"value": "<image>\nWhat changes do you observe in the non-neoplastic breast tissue?"
},
{
"from": "gpt",
"value": "The non-neoplastic breast tissue exhibits fibrocystic changes, characterized by expanded fibrous stroma and cyst formation. Additionally, microcalcifications are ... |
MorDetail_TCGA-L6-A4ET-01Z-00-DX1.C1AFDAD4-C9D5-423D-9647-ADBBEB693611-1 | TCGA-THCA/TCGA-L6-A4ET-01Z-00-DX1.C1AFDAD4-C9D5-423D-9647-ADBBEB693611.pt | [
{
"from": "human",
"value": "<image>\nAre overlapping nuclei observed in the neoplastic epithelial cells?"
},
{
"from": "gpt",
"value": "Yes, the neoplastic epithelial cells exhibit overlapping nuclei. The nuclei appear crowded within the cells, with their boundaries often obscuring one another.... |
Prognosis_TF_TCGA-D8-A1X5-01Z-00-DX2.E4D28EE2-9C87-4613-BD2E-89FBEF960DEE-1 | TCGA-BRCA/TCGA-D8-A1X5-01Z-00-DX2.E4D28EE2-9C87-4613-BD2E-89FBEF960DEE.pt | [
{
"from": "human",
"value": "<image>\nGiven the diagnosis of moderately differentiated invasive ductal carcinoma with partially signet ring cell features, is the prognosis good?"
},
{
"from": "gpt",
"value": "No"
}
] |
Diagnosis_choice_TCGA-A5-A1OJ-01Z-00-DX1.1A6D2CDF-A24E-4990-A2AB-91C13E22123B-2 | TCGA-UCEC/TCGA-A5-A1OJ-01Z-00-DX1.1A6D2CDF-A24E-4990-A2AB-91C13E22123B.pt | [
{
"from": "human",
"value": "<image>\nWhat is the FIGO grading of this tumor? A) FIGO grade I B) FIGO grade II C) FIGO grade III D) FIGO grade IV"
},
{
"from": "gpt",
"value": "B"
}
] |
Morphology_choice_TCGA-G7-6790-01Z-00-DX1.273810f2-dee2-4dc9-a8bd-9cbbacd8af3a-3 | TCGA-KIRP/TCGA-G7-6790-01Z-00-DX1.273810f2-dee2-4dc9-a8bd-9cbbacd8af3a.pt | [
{
"from": "human",
"value": "<image>\nWhat are the notable features of the cellular morphology in this slide? A) The cells have nuclei that are uniform and small, with inconspicuous nucleoli. B) Nuclei are very irregular, large, up to 20 micrometers, with prominent nucleoli. C) The cells display minimal nuc... |
MorDetail_TCGA-FI-A2F4-01Z-00-DX1.244933F2-B64B-434F-91C8-C90B73B2B4E2-5 | TCGA-UCEC/TCGA-FI-A2F4-01Z-00-DX1.244933F2-B64B-434F-91C8-C90B73B2B4E2.pt | [
{
"from": "human",
"value": "<image>\nAre malignant cells infiltrating the myometrial tissue?"
},
{
"from": "gpt",
"value": "Yes, malignant cells are infiltrating the myometrial tissue. These cells have extended beyond the endometrial lining and are invading deeper into the muscular layer of the... |
Prognosis_TF_TCGA-UB-A7MA-01Z-00-DX1.13804B83-8203-4A32-B8DE-5D1823EEC027-1 | TCGA-LIHC/TCGA-UB-A7MA-01Z-00-DX1.13804B83-8203-4A32-B8DE-5D1823EEC027.pt | [
{
"from": "human",
"value": "<image>\nWith a diagnosis of moderately differentiated mixed hepatocellular/cholangiocarcinoma, TNM staging of T2BM0N0, and IHC results showing patchy positive Arginase, strong CK19 positivity, and high MIB1 proliferation index, is the prognosis good?"
},
{
"from": "gpt"... |
MorDetail_TCGA-S7-A7WO-01Z-00-DX2.48F7608D-0FD5-4437-9CA9-6EA26DE7675B-4 | TCGA-PCPG/TCGA-S7-A7WO-01Z-00-DX2.48F7608D-0FD5-4437-9CA9-6EA26DE7675B.pt | [
{
"from": "human",
"value": "<image>\nDo the tumor cells exhibit high cellularity and cellular monotony?"
},
{
"from": "gpt",
"value": "Yes, there is high cellularity within the tumor, meaning there is a dense population of tumor cells. These cells display cellular monotony, with a uniform appea... |
MorDetail_TCGA-A8-A06Z-01Z-00-DX1.2BC8B71D-E01B-4CC1-B5E7-09BB54A5E1F8-3 | TCGA-BRCA/TCGA-A8-A06Z-01Z-00-DX1.2BC8B71D-E01B-4CC1-B5E7-09BB54A5E1F8.pt | [
{
"from": "human",
"value": "<image>\nHow do the glandular structures appear in the tissue?"
},
{
"from": "gpt",
"value": "The glandular structures show moderate formation but deviate significantly from normal architecture. They are irregular in shape and size and lack the organized arrangement ... |
MorDetail_TCGA-33-AASD-01Z-00-DX1.DAB3D05A-A6CE-47D1-90B6-79EBABAC3454-2 | TCGA-LUSC/TCGA-33-AASD-01Z-00-DX1.DAB3D05A-A6CE-47D1-90B6-79EBABAC3454.pt | [
{
"from": "human",
"value": "<image>\nDo the squamous epithelial cells show keratinization?"
},
{
"from": "gpt",
"value": "Indeed, the squamous epithelial cells display moderate differentiation with visible keratinization. This is characterized by the presence of eosinophilic, dense cytoplasm an... |
Treatment_TCGA-A2-A259-01Z-00-DX1.7289CD72-CB74-41D4-B4AC-4EA5FDFEC666-1 | TCGA-BRCA/TCGA-A2-A259-01Z-00-DX1.7289CD72-CB74-41D4-B4AC-4EA5FDFEC666.pt | [
{
"from": "human",
"value": "<image>\nWhat is the recommended treatment plan for a patient diagnosed with ER-positive, PR-positive, HER2-negative invasive ductal carcinoma, moderately differentiated, Grade 2, TNM stage T1cN0M0?"
},
{
"from": "gpt",
"value": "1. Surgery: Breast-conserving surgery... |
Morphology_TCGA-DX-A3LT-01Z-00-DX1.D4A948E5-6BDC-458B-BB69-ABE5742F148D-1 | TCGA-SARC/TCGA-DX-A3LT-01Z-00-DX1.D4A948E5-6BDC-458B-BB69-ABE5742F148D.pt | [
{
"from": "human",
"value": "<image>\nWhat observations can you make about the tissue architecture on this slide?"
},
{
"from": "gpt",
"value": "The tissue architecture on this slide shows a lesion that is well-encapsulated by a thin fibrous capsule. Within the encapsulated lesion, there are are... |
Conversation_TCGA-D8-A1X5-01Z-00-DX1.81B10B43-0D99-44D0-A245-D652041B8FEE-1 | TCGA-BRCA/TCGA-D8-A1X5-01Z-00-DX1.81B10B43-0D99-44D0-A245-D652041B8FEE.pt | [
{
"from": "human",
"value": "<image>\nCould you provide an overall description of the pathology slide?"
},
{
"from": "gpt",
"value": "Upon examining the pathology slide, there is a notable presence of invasive carcinoma with areas displaying signet ring cells. These tumor cells are actively infi... |
MorDetail_TCGA-W5-AA2R-11A-01-TS1.32EE025C-FFAD-4ED0-8D0E-8BCDC0FA44A9-3 | TCGA-CHOL/TCGA-W5-AA2R-11A-01-TS1.32EE025C-FFAD-4ED0-8D0E-8BCDC0FA44A9.pt | [
{
"from": "human",
"value": "<image>\nDo the tumor cells display marked nuclear pleomorphism?"
},
{
"from": "gpt",
"value": "Yes, the tumor cells exhibit marked nuclear pleomorphism. This is characterized by significant variability in nuclear size and shape. The nuclei are often enlarged and irr... |
Subtype_TCGA-PG-A5BC-01Z-00-DX4.860CCC5D-05A1-4630-8AE0-620825609F83-1 | TCGA-UCEC/TCGA-PG-A5BC-01Z-00-DX4.860CCC5D-05A1-4630-8AE0-620825609F83.pt | [
{
"from": "human",
"value": "<image>\nBased on the IHC results showing ER negative, PR positive, and p53 positive, what is the molecular subtype in this uterine carcinoma?"
},
{
"from": "gpt",
"value": "The molecular subtype is CN_HIGH."
}
] |
MorDetail_TCGA-BR-7957-01Z-00-DX1.870e24e0-b9cf-4baa-91f1-bd031d06da8e-1 | TCGA-STAD/TCGA-BR-7957-01Z-00-DX1.870e24e0-b9cf-4baa-91f1-bd031d06da8e.pt | [
{
"from": "human",
"value": "<image>\nDo the tumor cells show nuclear pleomorphism?"
},
{
"from": "gpt",
"value": "Yes, the tumor cells exhibit nuclear pleomorphism with moderate variability in size and shape. The nuclei are irregular, larger, and have distorted contours compared to normal cells... |
Conversation_TCGA-D6-6826-01Z-00-DX1.9346b65d-ffc0-46ed-b68b-e18b2a43c5ea-4 | TCGA-HNSC/TCGA-D6-6826-01Z-00-DX1.9346b65d-ffc0-46ed-b68b-e18b2a43c5ea.pt | [
{
"from": "human",
"value": "<image>\nWhat is the grading of this tumor according to the observed features?"
},
{
"from": "gpt",
"value": "The tumor is classified as Grade 2, indicating moderate differentiation. This grading reflects the tumor's structural organization and cellular features, whi... |
MorDetail_TCGA-50-6590-01Z-00-DX1.B08B2656-3DC7-4D35-A54D-9C57A7A773B3-1 | TCGA-LUAD/TCGA-50-6590-01Z-00-DX1.B08B2656-3DC7-4D35-A54D-9C57A7A773B3.pt | [
{
"from": "human",
"value": "<image>\nAre the cellular arrangements irregular and disorganized in the adenocarcinoma?"
},
{
"from": "gpt",
"value": "Yes, the cellular arrangements within the adenocarcinoma are highly irregular and disorganized. The cells appear haphazardly distributed, lacking a... |
MorDetail_TCGA-DK-A6B0-01Z-00-DX1.83628045-FDD9-4167-879F-7813FDCA7D97-5 | TCGA-BLCA/TCGA-DK-A6B0-01Z-00-DX1.83628045-FDD9-4167-879F-7813FDCA7D97.pt | [
{
"from": "human",
"value": "<image>\nDo you observe any signs of perineural invasion?"
},
{
"from": "gpt",
"value": "No, there are no signs of perineural invasion. The tumor does not appear to be infiltrating or surrounding nerve bundles within the tissue, suggesting confinement without nerve i... |
Morphology_TCGA-VQ-A8PY-01Z-00-DX1.EA2C7386-012A-442A-95B3-FFA12BD2684D-1 | TCGA-STAD/TCGA-VQ-A8PY-01Z-00-DX1.EA2C7386-012A-442A-95B3-FFA12BD2684D.pt | [
{
"from": "human",
"value": "<image>\nCan you describe the pattern of tumor infiltration?"
},
{
"from": "gpt",
"value": "The tumor exhibits an infiltrative growth pattern where the adenocarcinoma cells extend into the adjacent fat tissue. There is also evidence of lymphovascular invasion, with t... |
Stage_TCGA-49-4494-01Z-00-DX7.9f722476-622e-4374-9fda-ef35184f01e0-1 | TCGA-LUAD/TCGA-49-4494-01Z-00-DX7.9f722476-622e-4374-9fda-ef35184f01e0.pt | [
{
"from": "human",
"value": "<image>\nFor a patient with a tumor larger than 5cm, metastasis to 4 to 9 axillary lymph nodes, and no known distant metastasis, what would be the TNM staging?"
},
{
"from": "gpt",
"value": "The TNM staging for this patient is T3N2M0."
}
] |
Morphology_choice_TCGA-AR-A0TR-01Z-00-DX1.BBCE653F-7DD0-4830-BAD3-C06207A93853-2 | TCGA-BRCA/TCGA-AR-A0TR-01Z-00-DX1.BBCE653F-7DD0-4830-BAD3-C06207A93853.pt | [
{
"from": "human",
"value": "<image>\nHow does the tissue architecture of this infiltrating ductal carcinoma deviate from normal epithelial structures? A) The tumor shows highly organized glandular architecture, similar to normal glands. B) The tumor demonstrates moderate glandular formation with deviat... |
Morphology_choice_TCGA-TP-A8TV-01Z-00-DX1.16CEB4D6-1E14-4211-A9E8-D94EA0FBC2EE-3 | TCGA-PRAD/TCGA-TP-A8TV-01Z-00-DX1.16CEB4D6-1E14-4211-A9E8-D94EA0FBC2EE.pt | [
{
"from": "human",
"value": "<image>\nWhat are the notable features of the cellular morphology in this slide of prostate adenocarcinoma? A) The cells have uniform nuclei with minimal size and shape variability. B) The cells show significant pleomorphism with prominent nucleoli and a high rate of abnormal mi... |
Diagnosis_choice_TCGA-AC-A2FM-01Z-00-DX1.5D2309D5-C47B-4B04-B7B8-2F0685842889-1 | TCGA-BRCA/TCGA-AC-A2FM-01Z-00-DX1.5D2309D5-C47B-4B04-B7B8-2F0685842889.pt | [
{
"from": "human",
"value": "<image>\nBased on the observed features, what do you think is the correct histological classification of the tumor? A) Invasive lobular carcinoma B) Ductal carcinoma in situ C) Invasive ductal carcinoma D) Papillary carcinoma"
},
{
"from": "gpt",
"value": "C"... |
Conversation_TCGA-E9-A2JS-01Z-00-DX1.445BA2F8-3A4A-49D2-8D41-4ACFD32F2074-4 | TCGA-BRCA/TCGA-E9-A2JS-01Z-00-DX1.445BA2F8-3A4A-49D2-8D41-4ACFD32F2074.pt | [
{
"from": "human",
"value": "<image>\nWhat grading is applicable to this diagnosis based on the observed features?"
},
{
"from": "gpt",
"value": "In this instance, the lobular carcinoma is moderately differentiated, indicating an intermediate grade. The observed moderate differentiation of gland... |
MorDetail_TCGA-33-AASJ-01Z-00-DX1.0201CE2A-4DE6-4B4E-A010-37D773207F52-6 | TCGA-LUSC/TCGA-33-AASJ-01Z-00-DX1.0201CE2A-4DE6-4B4E-A010-37D773207F52.pt | [
{
"from": "human",
"value": "<image>\nDoes the tumor extend to the visceral pleura without breaching it?"
},
{
"from": "gpt",
"value": "Yes, the tumor extends subpleurally, reaching the visceral pleura but does not breach it. This extension highlights its invasive capacity while demonstrating a ... |
MorDetail_TCGA-WK-A8Y0-01Z-00-DX2.41422B74-E46A-44C5-8A7C-B8C18A4011E2-1 | TCGA-SARC/TCGA-WK-A8Y0-01Z-00-DX2.41422B74-E46A-44C5-8A7C-B8C18A4011E2.pt | [
{
"from": "human",
"value": "<image>\nDo the tumor cells exhibit nuclear pleomorphism?"
},
{
"from": "gpt",
"value": "Yes, the tumor cells exhibit pronounced nuclear pleomorphism. The nuclei vary greatly in size and shape, with some appearing markedly larger and more irregular than others. The c... |
Conversation_TCGA-RW-A67Y-01Z-00-DX1.7E8AD7AC-BF20-47E5-A17D-27BE8F1FDF06-2 | TCGA-PCPG/TCGA-RW-A67Y-01Z-00-DX1.7E8AD7AC-BF20-47E5-A17D-27BE8F1FDF06.pt | [
{
"from": "human",
"value": "<image>\nWhich observed features are the most important for making a diagnosis?"
},
{
"from": "gpt",
"value": "The most critical features include the well-circumscribed and encapsulated nature of the nodule, the red-brown and yellow-tan color variations with potentia... |
Morphology_choice_TCGA-21-1072-01Z-00-DX1.9e6c90ad-0529-4b8b-a4f8-1b05430600f9-1 | TCGA-LUSC/TCGA-21-1072-01Z-00-DX1.9e6c90ad-0529-4b8b-a4f8-1b05430600f9.pt | [
{
"from": "human",
"value": "<image>\nWhat is the observed pattern of tumor infiltration in this keratinizing squamous cell carcinoma specimen? A) The tumor cells are limited to the epithelial layer with no stromal invasion. B) The tumor cells infiltrate surrounding stroma, forming nests and sheets. C) Tumo... |
MorDetail_TCGA-4X-A9FC-01Z-00-DX2.DA082614-56B6-4797-A3A5-196CC85E1E97-4 | TCGA-THYM/TCGA-4X-A9FC-01Z-00-DX2.DA082614-56B6-4797-A3A5-196CC85E1E97.pt | [
{
"from": "human",
"value": "<image>\nDo you find any signs of vascular involvement within the tumor?"
},
{
"from": "gpt",
"value": "Yes, there are signs of possible vascular involvement. Tumor cells are seen in proximity to or within small vascular channels, although definitive invasion into th... |
Morphology_choice_TCGA-BQ-5891-01Z-00-DX1.8e19c5b6-693e-4f65-b1ce-ab1e9ca960ec-2 | TCGA-KIRP/TCGA-BQ-5891-01Z-00-DX1.8e19c5b6-693e-4f65-b1ce-ab1e9ca960ec.pt | [
{
"from": "human",
"value": "<image>\nHow does the tissue architecture of the tumor deviate from normal epithelial structures? A) The tumor shows glandular structures with moderate deviation from normal tissue architecture. B) The tumor forms highly organized acinar structures, similar to normal glands. C) ... |
Report_TCGA-2Z-A9JR-01Z-00-DX1.5F5DB6AD-BBEE-4D36-995F-56A78B6BFFE2-1 | TCGA-KIRP/TCGA-2Z-A9JR-01Z-00-DX1.5F5DB6AD-BBEE-4D36-995F-56A78B6BFFE2.pt | [
{
"from": "human",
"value": "<image>\nPlease provide a brief description and diagnosis based on the whole slide histopathology image."
},
{
"from": "gpt",
"value": "Microscopic observation of the pathology slide reveals papillary architectures of renal epithelial cells with a Fuhrman Nuclear Gra... |
Morphology_TCGA-EA-A3Y4-01Z-00-DX1.05FCBE75-3B24-4905-96D7-E9676EF69003-3 | TCGA-CESC/TCGA-EA-A3Y4-01Z-00-DX1.05FCBE75-3B24-4905-96D7-E9676EF69003.pt | [
{
"from": "human",
"value": "<image>\nWhat are the notable features of the cellular morphology in this slide?"
},
{
"from": "gpt",
"value": "The cellular morphology shows considerable pleomorphism, with cells exhibiting significant variability in size and shape. The nuclei are markedly hyperchro... |
Conversation_TCGA-S7-A7WO-01Z-00-DX1.732BD3CD-E11E-43E0-9FD8-98E09A16451A-1 | TCGA-PCPG/TCGA-S7-A7WO-01Z-00-DX1.732BD3CD-E11E-43E0-9FD8-98E09A16451A.pt | [
{
"from": "human",
"value": "<image>\nCan you provide an overall description of the whole slide image (WSI)?"
},
{
"from": "gpt",
"value": "The whole slide image displays a solidly alveolar pattern with multiple areas of necrosis and hemorrhage. The tumor is highly cellular, with extensive secti... |
Morphology_choice_TCGA-51-4081-01Z-00-DX1.5971d87d-5181-4c7a-91ea-2dfad1bc5fca-3 | TCGA-LUSC/TCGA-51-4081-01Z-00-DX1.5971d87d-5181-4c7a-91ea-2dfad1bc5fca.pt | [
{
"from": "human",
"value": "<image>\nWhat are the notable features of the cellular morphology in this slide? A) Cells exhibit high nuclear pleomorphism and frequent abnormal mitotic figures. B) Cells are moderately differentiated with keratinization, showing intercellular bridges. C) Cells are poorly diffe... |
MorDetail_TCGA-BH-A18Q-01Z-00-DX1.E89E49C7-D62A-4408-A3D9-19E79FCB249E-1 | TCGA-BRCA/TCGA-BH-A18Q-01Z-00-DX1.E89E49C7-D62A-4408-A3D9-19E79FCB249E.pt | [
{
"from": "human",
"value": "<image>\nDo the epithelial cells infiltrate the surrounding stromal tissue or exhibit invasiveness?"
},
{
"from": "gpt",
"value": "Yes, the epithelial cells are infiltrating the surrounding stromal tissue, demonstrating invasive characteristics. They have breached th... |
Report_TCGA-HI-7169-01Z-00-DX1.ac873262-34a1-4a47-8178-6a2a279c02e5-1 | TCGA-PRAD/TCGA-HI-7169-01Z-00-DX1.ac873262-34a1-4a47-8178-6a2a279c02e5.pt | [
{
"from": "human",
"value": "<image>\nPlease describe the main features of the whole slide histopathology image and provide a diagnosis."
},
{
"from": "gpt",
"value": "Microscopic observation of the pathology slide reveals glandular structures with altered architecture, showing a predominance of... |
Prognosis_TF_TCGA-AC-A3QQ-01Z-00-DX1.86463263-AB12-49FB-8967-D5FD1F7D221A-1 | TCGA-BRCA/TCGA-AC-A3QQ-01Z-00-DX1.86463263-AB12-49FB-8967-D5FD1F7D221A.pt | [
{
"from": "human",
"value": "<image>\nGiven the diagnosis of Grade II invasive lobular carcinoma with TNM staging MXT1CN0 (I-), and IHC findings showing strong positivity for both estrogen and progesterone receptors, HER-2 overexpression, and unfavorable Ki-67, is the prognosis good?"
},
{
"from": "... |
Morphology_TCGA-MO-A47R-01Z-00-DX1.FE880F3A-3E87-4CDE-A31E-FE7D5CA2FA66-1 | TCGA-SARC/TCGA-MO-A47R-01Z-00-DX1.FE880F3A-3E87-4CDE-A31E-FE7D5CA2FA66.pt | [
{
"from": "human",
"value": "<image>\nCan you describe the pattern of tumor infiltration?"
},
{
"from": "gpt",
"value": "The tumor infiltration shows evidence of vascular invasion, with tumor cells present within the blood vessel walls. The infiltration occurs alongside areas of necrosis and fib... |
Report_TCGA-AP-A1DK-01Z-00-DX1.6FBDDE22-98A5-4BD5-B3B3-D9ADB1EA311D-1 | TCGA-UCEC/TCGA-AP-A1DK-01Z-00-DX1.6FBDDE22-98A5-4BD5-B3B3-D9ADB1EA311D.pt | [
{
"from": "human",
"value": "<image>\nWhat does the whole slide histopathology image depict, and what is the diagnosis?"
},
{
"from": "gpt",
"value": "Microscopic observation of the pathology slide reveals gland-forming structures indicative of adenocarcinoma, with significant differentiation of... |
Morphology_TCGA-SW-A7EB-01Z-00-DX1.E9DE72F8-706D-43E2-A67E-7EDD39A509EB-1 | TCGA-STAD/TCGA-SW-A7EB-01Z-00-DX1.E9DE72F8-706D-43E2-A67E-7EDD39A509EB.pt | [
{
"from": "human",
"value": "<image>\nCan you describe the pattern of tumor infiltration?"
},
{
"from": "gpt",
"value": "The tumor demonstrates an infiltrative pattern, penetrating through the full thickness of the gastric wall. The infiltration is characterized by irregular clusters and nests o... |
MorDetail_TCGA-B2-5636-01Z-00-DX1.31aff50a-fa20-4f89-85e4-bc2417c4db46-3 | TCGA-KIRC/TCGA-B2-5636-01Z-00-DX1.31aff50a-fa20-4f89-85e4-bc2417c4db46.pt | [
{
"from": "human",
"value": "<image>\nDo the adjacent kidney tissues show any signs of sclerotic glomeruli or chronic inflammation?"
},
{
"from": "gpt",
"value": "Yes, the adjacent kidney tissue shows occasional sclerotic glomeruli, which appear shrunken and hyalinized. Additionally, there are a... |
MorDetail_TCGA-D3-A5GS-06Z-00-DX1.CA7E245E-86F6-4FB4-9BF9-BD8846FB023A-3 | TCGA-SKCM/TCGA-D3-A5GS-06Z-00-DX1.CA7E245E-86F6-4FB4-9BF9-BD8846FB023A.pt | [
{
"from": "human",
"value": "<image>\nIs extracapsular extension observed in the slides?"
},
{
"from": "gpt",
"value": "Yes, extracapsular extension is present. The melanoma has breached the lymph node capsule, indicating invasive growth beyond the confines of the node itself. This extension is ... |
Conversation_TCGA-55-8616-01Z-00-DX1.4F53B2AB-8221-4E67-80D2-7A8E3815B730-1 | TCGA-LUAD/TCGA-55-8616-01Z-00-DX1.4F53B2AB-8221-4E67-80D2-7A8E3815B730.pt | [
{
"from": "human",
"value": "<image>\nCan you describe the overall findings observed in this whole slide image?"
},
{
"from": "gpt",
"value": "The slide reveals a moderately differentiated adenocarcinoma characterized by glandular structures with some resemblance to normal lung tissue architectu... |
Morphology_choice_TCGA-GU-AATQ-01Z-00-DX1.6D436809-1238-44CA-9CFC-03DC2277C192-1 | TCGA-BLCA/TCGA-GU-AATQ-01Z-00-DX1.6D436809-1238-44CA-9CFC-03DC2277C192.pt | [
{
"from": "human",
"value": "<image>\nCan you describe the pattern of tumor infiltration in this specimen? A) Tumor cells infiltrate the perivesical tissue, extending into the extravesical area as a visible mass. B) Tumor cells are confined to the urothelium without any stromal invasion. C) Tumor cells rema... |
MorDetail_TCGA-HC-7230-01Z-00-DX1.da088457-3abd-4943-92e5-4b74d72010f1-3 | TCGA-PRAD/TCGA-HC-7230-01Z-00-DX1.da088457-3abd-4943-92e5-4b74d72010f1.pt | [
{
"from": "human",
"value": "<image>\nIs there any evidence of lymphovascular space invasion?"
},
{
"from": "gpt",
"value": "No, there is no evidence of lymphovascular space invasion. The examination of the surrounding blood vessels and lymphatic channels shows no presence of tumor cells within ... |
MorDetail_TCGA-D1-A16I-01Z-00-DX1.24C8F3CD-6AA8-48DD-BF07-3E6E2097C8F7-4 | TCGA-UCEC/TCGA-D1-A16I-01Z-00-DX1.24C8F3CD-6AA8-48DD-BF07-3E6E2097C8F7.pt | [
{
"from": "human",
"value": "<image>\nDo the tumor cells show irregular cell shapes and disorganized patterns?"
},
{
"from": "gpt",
"value": "Indeed, the tumor cells exhibit irregular cell shapes and a disorganized architectural pattern. There is a loss of cohesive growth, and the cells are arra... |
MorDetail_TCGA-A8-A09A-01Z-00-DX1.78773A6C-BA8A-46BE-AC2A-9C6FDAB45622-2 | TCGA-BRCA/TCGA-A8-A09A-01Z-00-DX1.78773A6C-BA8A-46BE-AC2A-9C6FDAB45622.pt | [
{
"from": "human",
"value": "<image>\nDo the tumor cells exhibit nuclear pleomorphism and hyperchromasia?"
},
{
"from": "gpt",
"value": "Yes, the tumor cells display prominent nuclear pleomorphism and hyperchromasia. The nuclei vary significantly in size and shape, featuring irregular and enlarg... |
Morphology_choice_TCGA-EB-A5FP-01Z-00-DX1.59E7B409-5166-4084-A667-EE52BE109A2A-1 | TCGA-SKCM/TCGA-EB-A5FP-01Z-00-DX1.59E7B409-5166-4084-A667-EE52BE109A2A.pt | [
{
"from": "human",
"value": "<image>\nCan you describe the pattern of tumor infiltration observed in this malignant melanoma specimen? A) Tumor cells are confined to the epidermis without evidence of deeper tissue invasion. B) Tumor cells show significant dermal invasion, with ulceration but no vascular inv... |
Diagnosis_choice_TCGA-OL-A66H-01Z-00-DX1.E54AF3FA-E59E-404C-BB83-A6FC6FC9B312-2 | TCGA-BRCA/TCGA-OL-A66H-01Z-00-DX1.E54AF3FA-E59E-404C-BB83-A6FC6FC9B312.pt | [
{
"from": "human",
"value": "<image>\nWhat is the Nottingham Histologic Grade (NHG) of this tumor? A) NHG1 B) NHG2 C) NHG3 D) NHG4"
},
{
"from": "gpt",
"value": "A"
}
] |
MorDetail_TCGA-YL-A8SI-01Z-00-DX1.35E5FB1A-9AAC-4942-892B-E9D80F6BDA23-3 | TCGA-PRAD/TCGA-YL-A8SI-01Z-00-DX1.35E5FB1A-9AAC-4942-892B-E9D80F6BDA23.pt | [
{
"from": "human",
"value": "<image>\nIs there evidence of areas corresponding to high-grade prostatic intraepithelial neoplasia?"
},
{
"from": "gpt",
"value": "Yes, areas corresponding to high-grade prostatic intraepithelial neoplasia (HGPIN) are present in the slide. These regions demonstrate ... |
Stage_TCGA-DD-AAVU-01Z-00-DX1.304704A9-9D90-4FD7-92A1-6361114D71C4-1 | TCGA-LIHC/TCGA-DD-AAVU-01Z-00-DX1.304704A9-9D90-4FD7-92A1-6361114D71C4.pt | [
{
"from": "human",
"value": "<image>\nA patient has a 3 cm tumor, no lymph node involvement, and no distant metastasis. What is the TNM staging?"
},
{
"from": "gpt",
"value": "The TNM staging for this patient is T2N0M0."
}
] |
Morphology_TCGA-KB-A93G-01Z-00-DX1.050F4602-DD6F-4E97-ACA8-3DE040485467-3 | TCGA-STAD/TCGA-KB-A93G-01Z-00-DX1.050F4602-DD6F-4E97-ACA8-3DE040485467.pt | [
{
"from": "human",
"value": "<image>\nWhat are the notable features of the cellular morphology in this slide?"
},
{
"from": "gpt",
"value": "The cellular morphology shows a significant presence of signet ring cells, characterized by large cytoplasmic vacuoles displacing the nucleus to the cell p... |
MorDetail_TCGA-AC-A62Y-01Z-00-DX1.5075F4DA-488C-40AD-BD73-6DE8953E1864-3 | TCGA-BRCA/TCGA-AC-A62Y-01Z-00-DX1.5075F4DA-488C-40AD-BD73-6DE8953E1864.pt | [
{
"from": "human",
"value": "<image>\nIs there evidence of an increased rate of cell division in the tumor?"
},
{
"from": "gpt",
"value": "Yes, there is a moderate increase in the rate of cell division within the tumor. This is indicated by an elevated number of mitotic figures present in the ar... |
Morphology_TCGA-39-5035-01Z-00-DX1.ad5d9143-f194-4cef-9a13-03190cf97ccf-1 | TCGA-LUSC/TCGA-39-5035-01Z-00-DX1.ad5d9143-f194-4cef-9a13-03190cf97ccf.pt | [
{
"from": "human",
"value": "<image>\nWhat observations can you make about the tissue architecture on this slide?"
},
{
"from": "gpt",
"value": "The tissue architecture reveals lymphoid tissue preserving its normal structure, with intact lymphoid follicles and germinal centers. There are no disr... |
MorDetail_TCGA-S9-A7IQ-01Z-00-DX1.3B4A20BF-6303-475D-BE85-014922FA02DA-3 | TCGA-LGG/TCGA-S9-A7IQ-01Z-00-DX1.3B4A20BF-6303-475D-BE85-014922FA02DA.pt | [
{
"from": "human",
"value": "<image>\nIs there any observable mitotic activity within the tumor?"
},
{
"from": "gpt",
"value": "No, there is no evident mitotic activity within the tumor. The absence of actively dividing cells correlates with the noted low proliferation index, reinforcing a more ... |
MorDetail_TCGA-BC-A69H-01Z-00-DX1.22CA7EA4-B8EC-444C-90AA-33095CC53585-2 | TCGA-LIHC/TCGA-BC-A69H-01Z-00-DX1.22CA7EA4-B8EC-444C-90AA-33095CC53585.pt | [
{
"from": "human",
"value": "<image>\nIs there evidence of extensive vascular invasion?"
},
{
"from": "gpt",
"value": "Yes, extensive vascular invasion is evident. Tumor cells are prominently seen within the lumens of multiple blood vessels, suggesting aggressive behavior. This invasion indicate... |
Conversation_TCGA-EA-A4BA-01Z-00-DX1.7EB090B2-E79E-417F-A871-247353679D7B-3 | TCGA-CESC/TCGA-EA-A4BA-01Z-00-DX1.7EB090B2-E79E-417F-A871-247353679D7B.pt | [
{
"from": "human",
"value": "<image>\nWhat is the histological classification based on your examination of the slide?"
},
{
"from": "gpt",
"value": "The histological classification for the observed features is adenocarcinoma. The presence of moderately differentiated glandular structures with ir... |
Conversation_TCGA-FD-A6TK-01Z-00-DX1.B685DA87-72A6-4C38-8AA1-40B6E543383C-1 | TCGA-BLCA/TCGA-FD-A6TK-01Z-00-DX1.B685DA87-72A6-4C38-8AA1-40B6E543383C.pt | [
{
"from": "human",
"value": "<image>\nCan you provide an overall description of the whole slide image?"
},
{
"from": "gpt",
"value": "The slide presents invasive urothelial carcinoma with a notable disruption of normal architecture. The malignant epithelial cells infiltrate through the musculari... |
Morphology_choice_TCGA-EA-A1QS-01Z-00-DX1.7BB98DFE-C3C5-459A-BEE8-6ECCEC27B223-2 | TCGA-CESC/TCGA-EA-A1QS-01Z-00-DX1.7BB98DFE-C3C5-459A-BEE8-6ECCEC27B223.pt | [
{
"from": "human",
"value": "<image>\nWhat are the notable features of the cellular morphology in this slide? A) There is minimal variability in nuclear size, with a low rate of cell division. B) Nuclei are uniform in appearance, showing no signs of active division. C) Nuclei appear extremely pleomorphic, w... |
Diagnosis_choice_TCGA-D5-7000-01Z-00-DX1.fb08c430-2c8c-486b-a39d-7d28c5eae189-1 | TCGA-COAD/TCGA-D5-7000-01Z-00-DX1.fb08c430-2c8c-486b-a39d-7d28c5eae189.pt | [
{
"from": "human",
"value": "<image>\nBased on the observed features, what do you think is the correct histological classification of the tumor? A) Adenocarcinoma with micropapillary features B) Adenocarcinoma tubulopapillare partim mucinosum C) Mucinous adenocarcinoma of the colon D) Adenosquamous carcinom... |
Conversation_TCGA-EW-A6SC-01Z-00-DX1.C2D50E7C-3AD0-4038-9A1C-CAE54A3FBE2F-1 | TCGA-BRCA/TCGA-EW-A6SC-01Z-00-DX1.C2D50E7C-3AD0-4038-9A1C-CAE54A3FBE2F.pt | [
{
"from": "human",
"value": "<image>\nCan you provide an overall description of the whole slide image (WSI)?"
},
{
"from": "gpt",
"value": "The whole slide image reveals a notable infiltration of malignant epithelial cells through the breast tissue stroma. These cells exhibit an arrangement char... |
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