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32,654,387
Transbound Emerg Dis
First expert elicitation of knowledge on drivers of emergence of the COVID-19 in pets.
Infection with the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) induces the coronavirus infectious disease 19 (COVID-19). Its pandemic form in human population and its probable animal origin, along with recent case reports in pets, make drivers of emergence crucial in domestic carnivore pets, especially...
covid-19;sars-cov-2;carnivores;clustering analysis;drivers;expert elicitation;pets;sensitivity analysis
Journal Article
Saegerman, Claude;Bianchini, Juana;Renault, Veronique;Haddad, Nadia;Humblet, Marie-France
10.1111/tbed.13724
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: First expert elicitation of knowledge on drivers of emergence of the COVID-19 in pets. [Abstract]: Infection with the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) induces the coronavirus infectious disease 19 (COVID-19). Its pandemic form in human population and its probable animal origin, alon...
32,974,370
Front Med (Lausanne)
COVID-19 Infection Among Healthcare Workers: Serological Findings Supporting Routine Testing.
A growing body of evidence demonstrates that asymptomatic and pre-symptomatic transmission of SARS-CoV-2 is a major contributor to the COVID-19 pandemic. Frontline healthcare workers in COVID-19 hotspots have faced numerous challenges, including shortages of personal protective equipment (PPE) and difficulties acquirin...
covid-19;sars-cov-2;asymptomatic infection;asymptomatic infection carriers;coronavirus;healthcare worker
Journal Article
Stock, Ariel D;Bader, Edward R;Cezayirli, Phillip;Inocencio, Julio;Chalmers, Samantha A;Yassari, Reza;Yanamadala, Vijay;Eskandar, Emad
10.3389/fmed.2020.00471
[ 0, 1, 1, 0, 1, 0, 0 ]
[Title]: COVID-19 Infection Among Healthcare Workers: Serological Findings Supporting Routine Testing. [Abstract]: A growing body of evidence demonstrates that asymptomatic and pre-symptomatic transmission of SARS-CoV-2 is a major contributor to the COVID-19 pandemic. Frontline healthcare workers in COVID-19 hotspots h...
32,900,207
Am J Med Qual
Practical Tips for Ambulatory Care in COVID-19: Lessons Learned in a New York Health System.
Although significant attention has been allocated to hospital management of COVID-19 patients during this pandemic, less discussed is the management of ambulatory patients. This has resulted in a challenge for ambulatory care providers in the management of COVID-19, particularly in areas with high disease prevalence. I...
covid-19;ambulatory practice;coronavirus;primary care
Journal Article
Sagar, Ankita;Gottridge, JoAnne;LaVine, Nancy
10.1177/1062860620954273
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Practical Tips for Ambulatory Care in COVID-19: Lessons Learned in a New York Health System. [Abstract]: Although significant attention has been allocated to hospital management of COVID-19 patients during this pandemic, less discussed is the management of ambulatory patients. This has resulted in a challenge ...
32,368,528
World J Clin Cases
Prevention program for the COVID-19 in a children's digestive endoscopy center.
The pneumonia caused by the coronavirus disease-2019 (COVID-19) outbreak in Wuhan, China constitutes a public health emergency of international concern. The gastrointestinal symptoms of vomiting, diarrhea and abdominal pain and the detection of COVID-19 nucleic acid from fecal specimens in a small number of patients su...
covid-19;digestive endoscopy;disinfection;nosocomial infection;pediatrics;prevention
Journal Article;Review
Ma, Xiao-Peng;Wang, Huan;Bai, Da-Ming;Zou, Yu;Zhou, Shao-Ming;Wen, Fei-Qiu;Dai, Dong-Ling
10.12998/wjcc.v8.i8.1343
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Prevention program for the COVID-19 in a children's digestive endoscopy center. [Abstract]: The pneumonia caused by the coronavirus disease-2019 (COVID-19) outbreak in Wuhan, China constitutes a public health emergency of international concern. The gastrointestinal symptoms of vomiting, diarrhea and abdominal ...
32,324,357
Orv Hetil
Challenges of intensive care and anesthesiology related to COVID-19 pandemic. Practical considerations
Due to the coronavirus epidemic, healthcare systems face growing challenges all around the world nowadays. These challenges are the most critical in the field of intensive treatment and anesthesiology. One of the most important prerequisites of effective critical care treatment is preserving the involved healthcare wor...
covid-19;az egeszsegugyi dolgozok szemelyi vedelme;coronavirus epidemy;intensive care;intenziv terapia;koronavirus-jarvany;personal protection of healthcare workers
Journal Article;Review
Fulesdi, Bela;Sarkany, Peter;Szentkereszty, Zoltan;Gal, Janos
10.1556/650.2020.31808
[ 1, 0, 1, 0, 0, 0, 0 ]
[Title]: Challenges of intensive care and anesthesiology related to COVID-19 pandemic. Practical considerations [Abstract]: Due to the coronavirus epidemic, healthcare systems face growing challenges all around the world nowadays. These challenges are the most critical in the field of intensive treatment and anesthesio...
32,710,669
J Med Virol
Validation and performance comparison of three SARS-CoV-2 antibody assays.
Serology testing of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is increasingly being used during the current pandemic of coronavirus disease 2019 (COVID-19), although its clinical and epidemiologic utilities are still debatable. Characterizing these assays provides scientific basis to best use them. T...
sars-cov-2;immunology;serology
Comparative Study;Journal Article;Validation Study
Paiva, Kimberly J;Grisson, Ricky D;Chan, Philip A;Huard, Richard C;Caliendo, Angela M;Lonks, John R;King, Ewa;Tang, Eric W;Pytel-Parenteau, Diane L;Nam, Ga H;Yakirevich, Evgeny;Lu, Shaolei
10.1002/jmv.26341
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Validation and performance comparison of three SARS-CoV-2 antibody assays. [Abstract]: Serology testing of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is increasingly being used during the current pandemic of coronavirus disease 2019 (COVID-19), although its clinical and epidemiologic utilitie...
32,868,970
Saudi Pharm J
Novel beta-Coronavirus (SARS-CoV-2): Current and future aspects of pharmacological treatments.
The novel coronavirus outbreak has reported to be rapidly spreading across the countries and becomes a foremost community health alarm. At present, no vaccine or specific drug is on hand for the treatment of this infectious disease. This review investigates the drugs, which are being evaluated and found to be effective...
anti-inflammatory agents;antiviral drugs;covid-19;corona virus;sars-cov-2
Journal Article;Review
Tiwari, Nidhi;Upadhyay, Jyoti;Ansari, Mohd Nazam;Joshi, Rohit
10.1016/j.jsps.2020.08.015
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Novel beta-Coronavirus (SARS-CoV-2): Current and future aspects of pharmacological treatments. [Abstract]: The novel coronavirus outbreak has reported to be rapidly spreading across the countries and becomes a foremost community health alarm. At present, no vaccine or specific drug is on hand for the treatment...
32,779,445
Cell J
Profiling of Initial Available SARS-CoV-2 Sequences from Iranian Related COVID-19 Patients.
The etiologic agent SARS-CoV-2 has caused the outbreak of COVID-19 which is spread widely around the world. It is vital to uncover and investigate the full genome sequence of SARS-CoV-2 throughout the world to track changes in this virus. To this purpose, SARS-CoV-2 full genome sequence profiling of 20 patients in Iran...
covid-19;nonsynonymous mutations;s protein;sars-cov-2
Journal Article
Salehi, Najmeh;Amiri-Yekta, Amir;Totonchi, Mehdi
10.22074/cellj.2020.7524
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Profiling of Initial Available SARS-CoV-2 Sequences from Iranian Related COVID-19 Patients. [Abstract]: The etiologic agent SARS-CoV-2 has caused the outbreak of COVID-19 which is spread widely around the world. It is vital to uncover and investigate the full genome sequence of SARS-CoV-2 throughout the world ...
33,048,372
Clin Transplant
Hydroxychloroquine and maintenance immunosuppression use in kidney transplant recipients: Analysis of linked US registry and claims data.
Hydroxychloroquine (HCQ) is an antimalarial drug with immunomodulatory effects used to treat systemic lupus erythematosus (SLE) and scleroderma. The antiviral effects of HCQ have raised attention in the context of the COVID-19 pandemic, although safety is controversial. We examined linkages of national transplant regis...
hydroxychloroquine;immunosuppression;kidney transplantation;outcomes;pharmacy claims;registries;scleroderma;systemic lupus erythematosus
Journal Article;Research Support, N.I.H., Extramural
Lentine, Krista L;Lam, Ngan N;Caliskan, Yasar;Alhamad, Tarek;Xiao, Huiling;Schnitzler, Mark A;Chang, Su-Hsin;Axelrod, David;Segev, Dorry L;McAdams-DeMarco, Mara;Kasiske, Bertram L;Hess, Gregory P;Brennan, Daniel C
10.1111/ctr.14118
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Hydroxychloroquine and maintenance immunosuppression use in kidney transplant recipients: Analysis of linked US registry and claims data. [Abstract]: Hydroxychloroquine (HCQ) is an antimalarial drug with immunomodulatory effects used to treat systemic lupus erythematosus (SLE) and scleroderma. The antiviral ef...
32,667,447
Rev Bras Ter Intensiva
Progression of confirmed COVID-19 cases after the implementation of control measures.
OBJECTIVE: To analyse the measures adopted by countries that have shown control over the transmission of coronavirus disease 2019 (COVID-19) and how each curve of accumulated cases behaved after the implementation of those measures. METHODS: The methodology adopted for this study comprises three phases: systemizing con...
Journal Article;Observational Study
Antunes, Bianca Brandao de Paula;Peres, Igor Tona;Baiao, Fernanda Araujo;Ranzani, Otavio Tavares;Bastos, Leonardo Dos Santos Lourenco;Silva, Amanda de Araujo Batista da;Souza, Guilherme Faveret Garcia de;Marchesi, Janaina Figueira;Dantas, Leila Figueiredo;Vargas, Soraida Aguilar;Macaira, Paula;Hamacher, Silvio;Bozza, F...
10.5935/0103-507x.20200028
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Progression of confirmed COVID-19 cases after the implementation of control measures. [Abstract]: OBJECTIVE: To analyse the measures adopted by countries that have shown control over the transmission of coronavirus disease 2019 (COVID-19) and how each curve of accumulated cases behaved after the implementation...
32,881,190
Oral Dis
Occupational COVID-19 risk to dental staff working in a public dental unit in the outbreak epicenter.
OBJECTIVE: The management of the COVID-19 outbreak occurred in Lombardy (Italy) implied that non-COVID-19 health care was remodeled, limiting adequate resources in non-hospital public dental healthcare settings. This situation offered the opportunity to investigate the occupational COVID-19 risk to dental staff in publ...
covid-19;sars-cov-2;dentistry;occupational risk
Journal Article
Nardone, Michele;Cordone, Angelo;Petti, Stefano
10.1111/odi.13632
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Occupational COVID-19 risk to dental staff working in a public dental unit in the outbreak epicenter. [Abstract]: OBJECTIVE: The management of the COVID-19 outbreak occurred in Lombardy (Italy) implied that non-COVID-19 health care was remodeled, limiting adequate resources in non-hospital public dental health...
33,023,033
Pharmaceutics
COVID-19: Current Developments and Further Opportunities in Drug Delivery and Therapeutics.
SARS-CoV-2 has affected people from all age groups, races and ethnicities. Given that many infected individuals are asymptomatic, they transmit the disease to others unknowingly, which has resulted in the spread of infection at an alarming rate. This review aims to provide an overview of the pathophysiology, preventive...
covid-19;sars-cov-2;coronavirus;drug delivery;immune response;immunization;infection;vaccine
Journal Article;Review
Zafar, Saman;Arshad, Muhammad Sohail;Fatima, Sameen;Ali, Amna;Zaman, Aliyah;Sayed, Elshaimaa;Chang, Ming-Wei;Ahmad, Zeeshan
10.3390/pharmaceutics12100945
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: COVID-19: Current Developments and Further Opportunities in Drug Delivery and Therapeutics. [Abstract]: SARS-CoV-2 has affected people from all age groups, races and ethnicities. Given that many infected individuals are asymptomatic, they transmit the disease to others unknowingly, which has resulted in the sp...
32,838,448
Z Geburtshilfe Neonatol
[Period Prevalence of SARS-CoV-2 in an Unselected Sample of Pregnant Women in Jena, Thuringia].
INTRODUCTION: Following an exponential increase in SARS-CoV-2 infections, the city of Jena, Thuringia, was the first in Germany to introduce mandatory mouth and nose coverings. An estimation of the SARS-CoV-2 period prevalence was achieved by screening an unselected cohort of pregnant women. Of interest was the number ...
Journal Article
Zollkau, Janine;Baier, Michael;Scherag, Andre;Schleussner, Ekkehard;Groten, Tanja
10.1055/a-1206-1033
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: [Period Prevalence of SARS-CoV-2 in an Unselected Sample of Pregnant Women in Jena, Thuringia]. [Abstract]: INTRODUCTION: Following an exponential increase in SARS-CoV-2 infections, the city of Jena, Thuringia, was the first in Germany to introduce mandatory mouth and nose coverings. An estimation of the SARS-...
32,437,926
Microbes Infect
From SARS-CoV to SARS-CoV-2: safety and broad-spectrum are important for coronavirus vaccine development.
The global pandemic of COVID-19 caused by SARS-CoV-2 (also known as 2019-nCoV and HCoV-19) has posed serious threats to public health and economic stability worldwide, thus calling for development of vaccines against SARS-CoV-2 and other emerging and reemerging coronaviruses. Since SARS-CoV-2 and SARS-CoV have high sim...
2019-ncov;cross-protection;hcov-19;sars-cov;sars-cov-2;vaccine
Journal Article;Research Support, Non-U.S. Gov't;Review
Ma, Cuiqing;Su, Shan;Wang, Jiachao;Wei, Lin;Du, Lanying;Jiang, Shibo
10.1016/j.micinf.2020.05.004
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: From SARS-CoV to SARS-CoV-2: safety and broad-spectrum are important for coronavirus vaccine development. [Abstract]: The global pandemic of COVID-19 caused by SARS-CoV-2 (also known as 2019-nCoV and HCoV-19) has posed serious threats to public health and economic stability worldwide, thus calling for developm...
32,589,735
J Am Med Inform Assoc
Telehealth in response to the COVID-19 pandemic: Implications for rural health disparities.
Telehealth programs have long held promise for addressing rural health disparities perpetuated by inadequate healthcare access. The COVID-19 (coronavirus disease 2019) pandemic and accompanying social distancing measures have hastened the implementation of telehealth programs in hospital systems around the globe. Here,...
covid-19;broadband;rural;telehealth;telemedicine
Journal Article
Hirko, Kelly A;Kerver, Jean M;Ford, Sabrina;Szafranski, Chelsea;Beckett, John;Kitchen, Chris;Wendling, Andrea L
10.1093/jamia/ocaa156
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Telehealth in response to the COVID-19 pandemic: Implications for rural health disparities. [Abstract]: Telehealth programs have long held promise for addressing rural health disparities perpetuated by inadequate healthcare access. The COVID-19 (coronavirus disease 2019) pandemic and accompanying social distan...
32,967,930
Sex Transm Infect
Early impact of COVID-19 social distancing measures on reported sexual behaviour of HIV pre-exposure prophylaxis users in Wales.
OBJECTIVES: To describe the early impact of COVID-19 and associated control measures on the sexual behaviour of pre-exposure prophylaxis (PrEP) users in Wales. METHODS: Data were obtained from an ecological momentary assessment study of PrEP use and sexual behaviour. Participants were individuals accessing PrEP through...
prep;condoms;sexual behaviour
Journal Article;Research Support, Non-U.S. Gov't
Gillespie, David;Knapper, Carys;Hughes, Dyfrig;Couzens, Zoe;Wood, Fiona;de Bruin, Marijn;Ma, Richard;Jones, Adam Thomas;Williams, Adam;Hood, Kerenza
10.1136/sextrans-2020-054598
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Early impact of COVID-19 social distancing measures on reported sexual behaviour of HIV pre-exposure prophylaxis users in Wales. [Abstract]: OBJECTIVES: To describe the early impact of COVID-19 and associated control measures on the sexual behaviour of pre-exposure prophylaxis (PrEP) users in Wales. METHODS: D...
32,746,670
J Dermatolog Treat
Change of dermatological practice after the COVID-19 outbreak resolves.
AIM: Dermatological care has already been deeply impacted by the coronavirus disease-2019 (COVID-19) epidemic. The consequences may continue long after the epidemic resolves. In this study, we aimed to evaluate the change of dermatological practice since the COVID-19 outbreak is almost controlled in mainland China. MAT...
covid-19;dermatology;dermatophytosis;outpatient
Journal Article
Gao, Chuang;Liu, Baoyi;Xie, Yongyi;Wu, Zhouwei
10.1080/09546634.2020.1799920
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Change of dermatological practice after the COVID-19 outbreak resolves. [Abstract]: AIM: Dermatological care has already been deeply impacted by the coronavirus disease-2019 (COVID-19) epidemic. The consequences may continue long after the epidemic resolves. In this study, we aimed to evaluate the change of de...
32,305,883
J Clin Virol
Coagulation disorders in coronavirus infected patients: COVID-19, SARS-CoV-1, MERS-CoV and lessons from the past.
Coronavirus disease 2019 (COVID-19) or severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel coronavirus strain disease, has recently emerged in China and rapidly spread worldwide. This novel strain is highly transmittable and severe disease has been reported in up to 16% of hospitalized cases. More tha...
covid-19;mers-cov;sars-cov;coagulation;coronavirus;thrombosis
Journal Article;Review
Giannis, Dimitrios;Ziogas, Ioannis A;Gianni, Panagiota
10.1016/j.jcv.2020.104362
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Coagulation disorders in coronavirus infected patients: COVID-19, SARS-CoV-1, MERS-CoV and lessons from the past. [Abstract]: Coronavirus disease 2019 (COVID-19) or severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel coronavirus strain disease, has recently emerged in China and rapidly spread...
32,325,421
Blood Cells Mol Dis
Increased expression of CD8 marker on T-cells in COVID-19 patients.
BACKGROUND: Cell-mediated immunity including T-cells (T helper and cytotoxic) plays an essential role in efficient antiviral responses against coronavirus disease-2019 (COVID-19). Therefore, in this study, we evaluated the ratio and expression of CD4 and CD8 markers in COVID-19 patients to clarify the immune characteri...
2019-ncov;cd4 lymphocyte;cd8 lymphocyte;covid-19;coronavirus
Journal Article
Ganji, Ali;Farahani, Iman;Khansarinejad, Behzad;Ghazavi, Ali;Mosayebi, Ghasem
10.1016/j.bcmd.2020.102437
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: Increased expression of CD8 marker on T-cells in COVID-19 patients. [Abstract]: BACKGROUND: Cell-mediated immunity including T-cells (T helper and cytotoxic) plays an essential role in efficient antiviral responses against coronavirus disease-2019 (COVID-19). Therefore, in this study, we evaluated the ratio an...
32,709,003
Int J Environ Res Public Health
Physical Activity, Screen Time, and Emotional Well-Being during the 2019 Novel Coronavirus Outbreak in China.
We aimed to evaluate the effects of the COVID-19 lock down on lifestyle in China during the initial stage of the pandemic. A questionnaire was distributed to Chinese adults living in 31 provinces of China via the internet using a snowball sampling strategy. Information on 7-day physical activity recall, screen time, an...
covid-19;lockdown;physical activity;psychological impact;screen time;sedentary lifestyle
Journal Article;Research Support, Non-U.S. Gov't
Qin, Fei;Song, Yiqing;Nassis, George P;Zhao, Lina;Dong, Yanan;Zhao, Cuicui;Feng, Yiwei;Zhao, Jiexiu
10.3390/ijerph17145170
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Physical Activity, Screen Time, and Emotional Well-Being during the 2019 Novel Coronavirus Outbreak in China. [Abstract]: We aimed to evaluate the effects of the COVID-19 lock down on lifestyle in China during the initial stage of the pandemic. A questionnaire was distributed to Chinese adults living in 31 pro...
32,293,098
Arthritis Rheumatol
On the Alert for Cytokine Storm: Immunopathology in COVID-19.
Poor outcomes in COVID-19 correlate with clinical and laboratory features of cytokine storm syndrome. Broad screening for cytokine storm and early, targeted antiinflammatory therapy may prevent immunopathology and could help conserve limited health care resources. While studies are ongoing, extrapolating from clinical ...
Journal Article;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't
Henderson, Lauren A;Canna, Scott W;Schulert, Grant S;Volpi, Stefano;Lee, Pui Y;Kernan, Kate F;Caricchio, Roberto;Mahmud, Shawn;Hazen, Melissa M;Halyabar, Olha;Hoyt, Kacie J;Han, Joseph;Grom, Alexei A;Gattorno, Marco;Ravelli, Angelo;De Benedetti, Fabrizio;Behrens, Edward M;Cron, Randy Q;Nigrovic, Peter A
10.1002/art.41285
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: On the Alert for Cytokine Storm: Immunopathology in COVID-19. [Abstract]: Poor outcomes in COVID-19 correlate with clinical and laboratory features of cytokine storm syndrome. Broad screening for cytokine storm and early, targeted antiinflammatory therapy may prevent immunopathology and could help conserve lim...
32,651,712
Int Orthop
The impact of COVID-19 pandemic on orthopaedic resident education: a nationwide survey study in South Korea.
PURPOSE: There have not been well-designed survey studies investigating the impact of the coronavirus disease 2019 (COVID-19) pandemic on orthopaedic resident education. METHODS: A 58-question, web-based survey was administered to orthopaedic residents in South Korea. A total of 229 orthopaedic residents from 43 hospit...
covid-19;education;impact;orthopaedic;resident
Journal Article
Chang, Dong-Gune;Park, Jong-Beom;Baek, Goo Hyun;Kim, Hong Jin;Bosco, Aju;Hey, Hwee Weng Dennis;Lee, Choon-Ki
10.1007/s00264-020-04714-7
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The impact of COVID-19 pandemic on orthopaedic resident education: a nationwide survey study in South Korea. [Abstract]: PURPOSE: There have not been well-designed survey studies investigating the impact of the coronavirus disease 2019 (COVID-19) pandemic on orthopaedic resident education. METHODS: A 58-questi...
32,855,772
Basic Clin Neurosci
COVID-19 and Substance Use Disorders: Recommendations to a Comprehensive Healthcare Response. An International Society of Addiction Medicine Practice and Policy Interest Group Position Paper.
Coronavirus Disease 2019 (COVID-19) is escalating all over the world and has higher morbidities and mortalities in certain vulnerable populations. People Who Use Drugs (PWUD) are a marginalized and stigmatized group with weaker immunity responses, vulnerability to stress, poor health conditions, high-risk behaviors, an...
addiction medicine;coronavirus;coronavirus disease 2019 (covid-19);harm reduction;methadone;opioid substitution therapy;pandemic;policy;public health;substance use disorder
Journal Article
Farhoudian, Ali;Baldacchino, Alexander;Clark, Nicolas;Gerra, Gilberto;Ekhtiari, Hamed;Dom, Geert;Mokri, Azarakhsh;Sadeghi, Mandana;Nematollahi, Pardis;Demasi, Maryanne;Schutz, Christian G;Hash-Emian, Seyed Mohammadreza;Tabarsi, Payam;Galea-Singer, Susanna;Carra, Giuseppe;Clausen, Thomas;Kouimtsidis, Christos;Tolomeo, S...
10.32598/bcn.11.covid19.1
[ 1, 0, 1, 0, 0, 0, 0 ]
[Title]: COVID-19 and Substance Use Disorders: Recommendations to a Comprehensive Healthcare Response. An International Society of Addiction Medicine Practice and Policy Interest Group Position Paper. [Abstract]: Coronavirus Disease 2019 (COVID-19) is escalating all over the world and has higher morbidities and mortali...
32,661,141
J Virol
Metabolic Syndrome and Viral Pathogenesis: Lessons from Influenza and Coronaviruses.
Metabolic syndrome increases the risk of severe disease due to viral infection. Yet few studies have assessed the pathogenesis of respiratory viruses in high-risk populations. Here, we summarize how metabolic dysregulation impairs immune responses, and we define the role of metabolism during influenza virus and coronav...
covid-19;sars-cov-2;diabetes;influenza;metabolic syndrome;models of metabolic syndrome;obesity;type 2 diabetes mellitus;viral pathogenesis
Journal Article;Research Support, N.I.H., Extramural;Review
Smith, Maria;Honce, Rebekah;Schultz-Cherry, Stacey
10.1128/JVI.00665-20
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Metabolic Syndrome and Viral Pathogenesis: Lessons from Influenza and Coronaviruses. [Abstract]: Metabolic syndrome increases the risk of severe disease due to viral infection. Yet few studies have assessed the pathogenesis of respiratory viruses in high-risk populations. Here, we summarize how metabolic dysre...
32,760,126
PLoS One
Commercial airline protocol during COVID-19 pandemic: An experience of Thai Airways International.
INTRODUCTION: Coronavirus disease 2019 (COVID-19) pandemic has affected the aviation industry. Existing protocols have relied on scientifically questionable evidence and might not lead to the optimal balance between public health safety and airlines' financial viability. OBJECTIVE: To explore the implementation feasibi...
Journal Article
Pongpirul, Krit;Kaewpoungngam, Kanitha;Chotirosniramit, Korn;Theprugsa, Sinnop
10.1371/journal.pone.0237299
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Commercial airline protocol during COVID-19 pandemic: An experience of Thai Airways International. [Abstract]: INTRODUCTION: Coronavirus disease 2019 (COVID-19) pandemic has affected the aviation industry. Existing protocols have relied on scientifically questionable evidence and might not lead to the optimal ...
32,682,217
Diagn Microbiol Infect Dis
COVID-19 - 6 million cases worldwide and an overview of the diagnosis in Brazil: a tragedy to be announced.
On 1 June 2020, 6 million cases of COVID-19 were recorded with a total of 374,927 deaths worldwide. Brazil, at that point, presented a total of 514,992 cases and 29,341 deaths caused by the COVID-19 disease. At that moment, Brazil appeared in the second position regarding number of cases, fourth in number of deaths, se...
brazil;covid-19;epidemiology;rt-pcr
Journal Article;Review
Marson, Fernando Augusto Lima
10.1016/j.diagmicrobio.2020.115113
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: COVID-19 - 6 million cases worldwide and an overview of the diagnosis in Brazil: a tragedy to be announced. [Abstract]: On 1 June 2020, 6 million cases of COVID-19 were recorded with a total of 374,927 deaths worldwide. Brazil, at that point, presented a total of 514,992 cases and 29,341 deaths caused by the C...
32,480,154
Sci Total Environ
Medical mask versus cotton mask for preventing respiratory droplet transmission in micro environments.
The objective of this study was to investigate whether cotton mask worn by respiratory infection person could suppress respiratory droplet levels compared to medical mask. We recruited adult volunteers with confirmed influenza and suspected cases of coronavirus disease 2019 (COVID-19) to wear medical masks and self-des...
cotton mask;medical mask;micro environment;respiratory droplet;transmission
Journal Article
Ho, Kin-Fai;Lin, Lian-Yu;Weng, Shao-Ping;Chuang, Kai-Jen
10.1016/j.scitotenv.2020.139510
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Medical mask versus cotton mask for preventing respiratory droplet transmission in micro environments. [Abstract]: The objective of this study was to investigate whether cotton mask worn by respiratory infection person could suppress respiratory droplet levels compared to medical mask. We recruited adult volun...
32,515,254
J Am Heart Assoc
Coronavirus Disease 2019 Catheterization Laboratory Survey.
Background The coronavirus disease 2019 pandemic is expected to affect operations and lifestyles of interventional cardiologists around the world in unprecedented ways. Timely gathering of information on this topic can provide valuable insight and improve the handling of the ongoing and future pandemic outbreaks. Metho...
covid-19;catheterization laboratory;coronavirus disease 2019;survey
Journal Article
Banerjee, Subhash;Tarantini, Giuseppe;Abu-Fadel, Mazen;Banerjee, Avantika;Little, Bertis B;Sorajja, Paul;Shishehbor, Mehdi H;Brilakis, Emmanouil S
10.1161/JAHA.120.017175
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Coronavirus Disease 2019 Catheterization Laboratory Survey. [Abstract]: Background The coronavirus disease 2019 pandemic is expected to affect operations and lifestyles of interventional cardiologists around the world in unprecedented ways. Timely gathering of information on this topic can provide valuable ins...
32,392,072
J Phys Chem Lett
Novel Coronavirus Polymerase and Nucleotidyl-Transferase Structures: Potential to Target New Outbreaks.
The pandemic outbreak of a new coronavirus (CoV), SARS-CoV-2, has captured the world's attention, demonstrating that CoVs represent a continuous global threat. As this is a highly contagious virus, it is imperative to understand RNA-dependent-RNA-polymerase (RdRp), the key component in virus replication. Although the S...
Journal Article
Zhang, Wen-Fa;Stephen, Preyesh;Theriault, Jean-Francois;Wang, Ruixuan;Lin, Sheng-Xiang
10.1021/acs.jpclett.0c00571
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Novel Coronavirus Polymerase and Nucleotidyl-Transferase Structures: Potential to Target New Outbreaks. [Abstract]: The pandemic outbreak of a new coronavirus (CoV), SARS-CoV-2, has captured the world's attention, demonstrating that CoVs represent a continuous global threat. As this is a highly contagious viru...
33,051,391
Brain Nerve
[COVID-19 and the Hospital Neurologist: How should we confront the COVID pandemic?]
Ninety-six patients were admitted to our hospital during the first wave of the 2020 COVID pandemic. Our hospital, a core hospital in Kobe, was in confusion at the beginning of the pandemic. The following three factors were considered important for preventing the collapse of hospitals during the pandemic based on our ex...
Journal Article
Kohara, Nobuo;Kawamoto, Michi
10.11477/mf.1416201647
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: [COVID-19 and the Hospital Neurologist: How should we confront the COVID pandemic?] [Abstract]: Ninety-six patients were admitted to our hospital during the first wave of the 2020 COVID pandemic. Our hospital, a core hospital in Kobe, was in confusion at the beginning of the pandemic. The following three facto...
32,910,347
Virol Sin
Comparative Antiviral Efficacy of Viral Protease Inhibitors against the Novel SARS-CoV-2 In Vitro.
The recent outbreak of novel coronavirus pneumonia (COVID-19) caused by a new coronavirus has posed a great threat to public health. Identifying safe and effective antivirals is of urgent demand to cure the huge number of patients. Virus-encoded proteases are considered potential drug targets. The human immunodeficienc...
covid-19;protease inhibitor;respiratory pharmacology;sars-cov-2
Journal Article
Zhang, Leike;Liu, Jia;Cao, Ruiyuan;Xu, Mingyue;Wu, Yan;Shang, Weijuan;Wang, Xi;Zhang, Huanyu;Jiang, Xiaming;Sun, Yuan;Hu, Hengrui;Li, Yufeng;Zou, Gang;Zhang, Min;Zhao, Lei;Li, Wei;Guo, Xiaojia;Zhuang, Xiaomei;Yang, Xing-Lou;Shi, Zheng-Li;Deng, Fei;Hu, Zhihong;Xiao, Gengfu;Wang, Manli;Zhong, Wu
10.1007/s12250-020-00288-1
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Comparative Antiviral Efficacy of Viral Protease Inhibitors against the Novel SARS-CoV-2 In Vitro. [Abstract]: The recent outbreak of novel coronavirus pneumonia (COVID-19) caused by a new coronavirus has posed a great threat to public health. Identifying safe and effective antivirals is of urgent demand to cu...
32,337,664
Clin Drug Investig
Rational Use of Tocilizumab in the Treatment of Novel Coronavirus Pneumonia.
Since December 2019, a novel coronavirus pneumonia (COVID-19) has broken out in Wuhan, China and spread rapidly. Recent studies have found that 15.7% of patients develop severe pneumonia, and cytokine storm is an important factor leading to rapid disease progression. Currently, there are no specific drugs for COVID-19 ...
Journal Article;Review
Zhang, Shengyu;Li, Lei;Shen, Aizong;Chen, Yongwu;Qi, Zhigang
10.1007/s40261-020-00917-3
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Rational Use of Tocilizumab in the Treatment of Novel Coronavirus Pneumonia. [Abstract]: Since December 2019, a novel coronavirus pneumonia (COVID-19) has broken out in Wuhan, China and spread rapidly. Recent studies have found that 15.7% of patients develop severe pneumonia, and cytokine storm is an important...
32,431,992
Cureus
Extracorporeal Membrane Oxygenation as Treatment of Severe COVID-19 Infection: A Case Report.
Novel coronavirus 2019 (COVID-19) is a severe respiratory infection leading to acute respiratory distress syndrome (ARDS) accounting for thousands of cases and deaths across the world. Several alternatives in treatment options have been assessed and used in this patient population. However, when mechanical ventilation ...
ards;coronavirus;covid-19;ecmo;infection;respiratory
Case Reports
Douedi, Steven;Alshami, Abbas;Costanzo, Eric
10.7759/cureus.7714
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Extracorporeal Membrane Oxygenation as Treatment of Severe COVID-19 Infection: A Case Report. [Abstract]: Novel coronavirus 2019 (COVID-19) is a severe respiratory infection leading to acute respiratory distress syndrome (ARDS) accounting for thousands of cases and deaths across the world. Several alternatives...
32,356,047
Knee Surg Sports Traumatol Arthrosc
Massive cutback in orthopaedic healthcare services due to the COVID-19 pandemic.
PURPOSE: Due to the lack of evidence, it was the aim of the study to investigate current possible cutbacks in orthopaedic healthcare due to the coronavirus disease 2019 pandemic (COVID-19). METHODS: An online survey was performed of orthopaedic surgeons in the German-speaking Arthroscopy Society (Gesellschaft fur Arthr...
arthroplasty;arthroscopy;covid-19;coronavirus disease 2019;health-care;ligament reconstruction;orthopaedic;rotator cuff;sars-cov-2;severe acute respiratory syndrome coronavirus 2
Journal Article
Liebensteiner, M C;Khosravi, I;Hirschmann, M T;Heuberer, P R;Thaler, M
10.1007/s00167-020-06032-2
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Massive cutback in orthopaedic healthcare services due to the COVID-19 pandemic. [Abstract]: PURPOSE: Due to the lack of evidence, it was the aim of the study to investigate current possible cutbacks in orthopaedic healthcare due to the coronavirus disease 2019 pandemic (COVID-19). METHODS: An online survey wa...
33,015,722
Pediatr Cardiol
Role of a Pediatric Cardiologist in the COVID-19 Pandemic.
Coronavirus disease 2019 (COVID-19) has affected patients across all age groups, with a wide range of illness severity from asymptomatic carriers to severe multi-organ dysfunction and death. Although early reports have shown that younger age groups experience less severe disease than older adults, our understanding of ...
covid-19;cardiovascular;mis-c;pediatric
Journal Article;Review
Niaz, Talha;Hope, Kyle;Fremed, Michael;Misra, Nilanjana;Altman, Carrie;Glickstein, Julie;Sanchez-de-Toledo, Joan;Fraisse, Alain;Miller, Jacob;Snyder, Christopher;Johnson, Jonathan N;Chowdhury, Devyani
10.1007/s00246-020-02476-y
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Role of a Pediatric Cardiologist in the COVID-19 Pandemic. [Abstract]: Coronavirus disease 2019 (COVID-19) has affected patients across all age groups, with a wide range of illness severity from asymptomatic carriers to severe multi-organ dysfunction and death. Although early reports have shown that younger ag...
32,336,243
Semin Cardiothorac Vasc Anesth
Anesthesia and COVID-19: What We Should Know and What We Should Do.
Coronavirus disease 2019 (COVID-19), caused by Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2), was first reported in Wuhan, Hubei, China, and has spread to more than 200 other countries around the world. COVID-19 is a highly contagious disease with continuous human-to-human transmission. The origin of the...
covid-19;mers;ppe;rt-pcr test;sars-cov-2;anesthesia;coronavirus;epidemiology;pandemic;pneumonia
Journal Article;Review
Tang, Linda Y;Wang, Jingping
10.1177/1089253220921590
[ 1, 1, 1, 0, 0, 0, 0 ]
[Title]: Anesthesia and COVID-19: What We Should Know and What We Should Do. [Abstract]: Coronavirus disease 2019 (COVID-19), caused by Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2), was first reported in Wuhan, Hubei, China, and has spread to more than 200 other countries around the world. COVID-19 is a...
32,772,283
Intern Emerg Med
The association between cardiac injury and outcomes in hospitalized patients with COVID-19.
In this study, we aimed to assess the association between development of cardiac injury and short-term mortality as well as poor in-hospital outcomes in hospitalized patients with COVID-19. In this prospective, single-center study, we enrolled hospitalized patients with laboratory-confirmed COVID-19 and highly suspicio...
covid-19;cardiovascular;mortality;sars-cov-2
Journal Article
Karbalai Saleh, Shahrokh;Oraii, Alireza;Soleimani, Abbas;Hadadi, Azar;Shajari, Zahra;Montazeri, Mahnaz;Moradi, Hedieh;Talebpour, Mohammad;Sadat Naseri, Azadeh;Balali, Pargol;Akhbari, Mahsa;Ashraf, Haleh
10.1007/s11739-020-02466-1
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: The association between cardiac injury and outcomes in hospitalized patients with COVID-19. [Abstract]: In this study, we aimed to assess the association between development of cardiac injury and short-term mortality as well as poor in-hospital outcomes in hospitalized patients with COVID-19. In this prospecti...
32,804,081
Elife
Inference from longitudinal laboratory tests characterizes temporal evolution of COVID-19-associated coagulopathy (CAC).
Temporal inference from laboratory testing results and triangulation with clinical outcomes extracted from unstructured electronic health record (EHR) provider notes is integral to advancing precision medicine. Here, we studied 246 SARS-CoV-2 PCR-positive (COVIDpos) patients and propensity-matched 2460 SARS-CoV-2 PCR-n...
covid-19;sars-cov-2;coagulation;electronic health record (ehr);human;laboratory tests;medicine;thrombolytic agents
Journal Article
Pawlowski, Colin;Wagner, Tyler;Puranik, Arjun;Murugadoss, Karthik;Loscalzo, Liam;Venkatakrishnan, A J;Pruthi, Rajiv K;Houghton, Damon E;O'Horo, John C;Morice, William G 2nd;Williams, Amy W;Gores, Gregory J;Halamka, John;Badley, Andrew D;Barnathan, Elliot S;Makimura, Hideo;Khan, Najat;Soundararajan, Venky
10.7554/eLife.59209
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Inference from longitudinal laboratory tests characterizes temporal evolution of COVID-19-associated coagulopathy (CAC). [Abstract]: Temporal inference from laboratory testing results and triangulation with clinical outcomes extracted from unstructured electronic health record (EHR) provider notes is integral ...
32,680,658
Gac Sanit
[Predictive models of the COVID-19 epidemic in Spain with Gompertz curves].
During the international health crisis caused by the COVID-19 pandemic, it is necessary not only to know the data on infections, deaths and the occupation of hospital beds, but also to make predictions that help health authorities in the management of the crisis. The present work aims to describe the methodology used t...
covid-19;forecasting;mortalidad;mortality;prediccion
English Abstract;Journal Article
Sanchez-Villegas, Pablo;Daponte Codina, Antonio
10.1016/j.gaceta.2020.05.005
[ 0, 0, 0, 0, 0, 1, 0 ]
[Title]: [Predictive models of the COVID-19 epidemic in Spain with Gompertz curves]. [Abstract]: During the international health crisis caused by the COVID-19 pandemic, it is necessary not only to know the data on infections, deaths and the occupation of hospital beds, but also to make predictions that help health auth...
32,679,056
Antiviral Res
Lower prevalence of antibodies neutralizing SARS-CoV-2 in group O French blood donors.
We investigated the distribution of antibodies neutralizing SARS-CoV-2 according to age, sex or blood group in French blood donors. In 464 samples collected before the emergence of SARS-CoV-2 (2017 and 2018), our virus neutralization assay had a 100% specificity. It was used to test 998 samples collected from blood don...
blood donors;blood groups;covid-19;sars-cov-2;seroneutralisation
Journal Article;Research Support, Non-U.S. Gov't
Gallian, Pierre;Pastorino, Boris;Morel, Pascal;Chiaroni, Jacques;Ninove, Laetitia;de Lamballerie, Xavier
10.1016/j.antiviral.2020.104880
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Lower prevalence of antibodies neutralizing SARS-CoV-2 in group O French blood donors. [Abstract]: We investigated the distribution of antibodies neutralizing SARS-CoV-2 according to age, sex or blood group in French blood donors. In 464 samples collected before the emergence of SARS-CoV-2 (2017 and 2018), our...
32,290,754
Immunotherapy
Do checkpoint inhibitors compromise the cancer patients' immunity and increase the vulnerability to COVID-19 infection?
The severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) has been declared a pandemic by the WHO that claimed the lives of thousands of people within a few months. Cancer patients represent a vulnerable population due to the acquired immunodeficiency associated with anti-cancer therapy. Immune checkpoint inhibi...
covid-19;cancer;checkpoints inhibitors;coronavirus;immune therapy;immunosuppression
Editorial
Kattan, Joseph;Kattan, Clarisse;Assi, Tarek
10.2217/imt-2020-0077
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Do checkpoint inhibitors compromise the cancer patients' immunity and increase the vulnerability to COVID-19 infection? [Abstract]: The severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) has been declared a pandemic by the WHO that claimed the lives of thousands of people within a few months. Cancer ...
32,172,226
Clin Chem Lab Med
Prominent changes in blood coagulation of patients with SARS-CoV-2 infection.
Background As the number of patients increases, there is a growing understanding of the form of pneumonia sustained by the 2019 novel coronavirus (SARS-CoV-2), which has caused an outbreak in China. Up to now, clinical features and treatment of patients infected with SARS-CoV-2 have been reported in detail. However, th...
sars-cov-2;blood coagulation;coronavirus disease 2019
Journal Article
Han, Huan;Yang, Lan;Liu, Rui;Liu, Fang;Wu, Kai-Lang;Li, Jie;Liu, Xing-Hui;Zhu, Cheng-Liang
10.1515/cclm-2020-0188
[ 0, 0, 0, 1, 0, 0, 0 ]
[Title]: Prominent changes in blood coagulation of patients with SARS-CoV-2 infection. [Abstract]: Background As the number of patients increases, there is a growing understanding of the form of pneumonia sustained by the 2019 novel coronavirus (SARS-CoV-2), which has caused an outbreak in China. Up to now, clinical fe...
32,916,249
Int J Infect Dis
Integrated control of COVID-19 in resource-poor countries.
Low- and middle-income countries (LMICs) face many challenges in controlling COVID-19. Healthcare resources are limited and so are ICU beds. RT-PCR testing is conducted on a limited scale and treatment options are few. There is no vaccine. Therefore, what low-cost solutions remain for the prevention, diagnosis, and tre...
sars-cov-2;control;diagnostics;hygiene;therapeutics;vaccination
Editorial
Aziz, Asma B;Raqib, Rubhana;Khan, Wasif A;Rahman, Mahbubur;Haque, Rashidul;Alam, Munir;Zaman, K;Ross, Allen G
10.1016/j.ijid.2020.09.009
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Integrated control of COVID-19 in resource-poor countries. [Abstract]: Low- and middle-income countries (LMICs) face many challenges in controlling COVID-19. Healthcare resources are limited and so are ICU beds. RT-PCR testing is conducted on a limited scale and treatment options are few. There is no vaccine. ...
33,026,344
Ann Biol Clin (Paris)
[Management of the thrombotic risk associated with COVID-19: what is the role of the hemostasis laboratory?]
COVID-19 is associated with disturbances of hemostasis in the laboratory and an increased thrombotic risk. Routine laboratory tests - activated partial thromboplastin time (aPTT), prothrombin time, Clauss fibrinogen and D-dimers levels measurement - are used for the evaluation of the thrombotic risk and the monitoring ...
covid-19;d-dimers;anticoagulation;coagulopathy;thrombosis
Journal Article;Review
Hardy, Michael;Douxfils, Jonathan;Dogne, Jean-Michel;Lessire, Sarah;Chatelain, Bernard;Testa, Sophie;Gouin-Thibault, Isabelle;Gruel, Yves;Lecompte, Thomas;Mullier, Francois
10.1684/abc.2020.1581
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: [Management of the thrombotic risk associated with COVID-19: what is the role of the hemostasis laboratory?] [Abstract]: COVID-19 is associated with disturbances of hemostasis in the laboratory and an increased thrombotic risk. Routine laboratory tests - activated partial thromboplastin time (aPTT), prothrombi...
32,983,254
Infect Agent Cancer
Clinical management of lung cancer patients during the outbreak of COVID-19 epidemic.
The rapid growth of 2019 novel coronavirus (COVID-19) outbreak in Wuhan, China, at the early December 2019. COVID-19 spread all over the word just a few months. The outbreak of COVID-19 infection poses major threat to international health and economy. World Health Organization (WHO) announced that the new coronavirus w...
covid-19;lung cancer;patient management
Journal Article;Review
Wang, Li;Jiang, Man;Qu, Jialin;Zhou, Na;Zhang, Xiaochun
10.1186/s13027-020-00322-7
[ 1, 0, 1, 0, 0, 0, 0 ]
[Title]: Clinical management of lung cancer patients during the outbreak of COVID-19 epidemic. [Abstract]: The rapid growth of 2019 novel coronavirus (COVID-19) outbreak in Wuhan, China, at the early December 2019. COVID-19 spread all over the word just a few months. The outbreak of COVID-19 infection poses major threa...
32,070,465
Euro Surveill
First cases of coronavirus disease 2019 (COVID-19) in France: surveillance, investigations and control measures, January 2020.
A novel coronavirus (severe acute respiratory syndrome coronavirus 2, SARS-CoV-2) causing a cluster of respiratory infections (coronavirus disease 2019, COVID-19) in Wuhan, China, was identified on 7 January 2020. The epidemic quickly disseminated from Wuhan and as at 12 February 2020, 45,179 cases have been confirmed ...
covid-19, sars-cov-2, 2019-ncov;france;surveillance;contact tracing;containment;coronavirus
Case Reports;Journal Article
Bernard Stoecklin, Sibylle;Rolland, Patrick;Silue, Yassoungo;Mailles, Alexandra;Campese, Christine;Simondon, Anne;Mechain, Matthieu;Meurice, Laure;Nguyen, Mathieu;Bassi, Clement;Yamani, Estelle;Behillil, Sylvie;Ismael, Sophie;Nguyen, Duc;Malvy, Denis;Lescure, Francois Xavier;Georges, Scarlett;Lazarus, Clement;Tabai, An...
10.2807/1560-7917.ES.2020.25.6.2000094
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: First cases of coronavirus disease 2019 (COVID-19) in France: surveillance, investigations and control measures, January 2020. [Abstract]: A novel coronavirus (severe acute respiratory syndrome coronavirus 2, SARS-CoV-2) causing a cluster of respiratory infections (coronavirus disease 2019, COVID-19) in Wuhan,...
32,062,957
Zhonghua Jie He He Hu Xi Za Zhi
[Clinical characteristics of 30 medical workers infected with new coronavirus pneumonia].
Objective: To investigate the clinical characteristics of medical staff with novel coronavirus pneumonia(NCP). Methods: 30 patients infected with novel coronavirus referred to jianghan university hospital between January 11, 2020 and January 3, 2020 were studied. The data reviewed included those of clinical manifestati...
medical workers;novel coronavirus;pneumonia
English Abstract;Journal Article
Liu, M;He, P;Liu, H G;Wang, X J;Li, F J;Chen, S;Lin, J;Chen, P;Liu, J H;Li, C H
10.3760/cma.j.issn.1001-0939.2020.0016
[ 0, 0, 1, 1, 0, 0, 0 ]
[Title]: [Clinical characteristics of 30 medical workers infected with new coronavirus pneumonia]. [Abstract]: Objective: To investigate the clinical characteristics of medical staff with novel coronavirus pneumonia(NCP). Methods: 30 patients infected with novel coronavirus referred to jianghan university hospital betw...
32,446,778
Cytokine Growth Factor Rev
The cytokine storm in COVID-19: An overview of the involvement of the chemokine/chemokine-receptor system.
In 2019-2020 a new coronavirus named SARS-CoV-2 was identified as the causative agent of a several acute respiratory infection named COVID-19, which is causing a worldwide pandemic. There are still many unresolved questions regarding the pathogenesis of this disease and especially the reasons underlying the extremely d...
covid-19;cxcl10;cxcl8;chemokines;coronavirus;cytokine storm
Journal Article;Review
Coperchini, Francesca;Chiovato, Luca;Croce, Laura;Magri, Flavia;Rotondi, Mario
10.1016/j.cytogfr.2020.05.003
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: The cytokine storm in COVID-19: An overview of the involvement of the chemokine/chemokine-receptor system. [Abstract]: In 2019-2020 a new coronavirus named SARS-CoV-2 was identified as the causative agent of a several acute respiratory infection named COVID-19, which is causing a worldwide pandemic. There are ...
32,864,270
Cureus
Predicting COVID-19 Pneumonia Severity on Chest X-ray With Deep Learning.
Introduction The need to streamline patient management for coronavirus disease-19 (COVID-19) has become more pressing than ever. Chest X-rays (CXRs) provide a non-invasive (potentially bedside) tool to monitor the progression of the disease. In this study, we present a severity score prediction model for COVID-19 pneum...
chest x-ray;covid-19 pneumonia;deep learning artificial intelligence;severity scoring
Journal Article
Cohen, Joseph Paul;Dao, Lan;Roth, Karsten;Morrison, Paul;Bengio, Yoshua;Abbasi, Almas F;Shen, Beiyi;Mahsa, Hoshmand Kochi;Ghassemi, Marzyeh;Li, Haifang;Duong, Tim
10.7759/cureus.9448
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Predicting COVID-19 Pneumonia Severity on Chest X-ray With Deep Learning. [Abstract]: Introduction The need to streamline patient management for coronavirus disease-19 (COVID-19) has become more pressing than ever. Chest X-rays (CXRs) provide a non-invasive (potentially bedside) tool to monitor the progression...
32,616,990
J Orthop
Spinal surgery in COVID-19 pandemic era: One trauma hub center experience in central-southern Italy.
The aim of the study is to analyze and report the results of the surgical activity in a spinal unit of a trauma hub in central Italy during COVID-19 pandemic. Surgical activity was compared between COVID 19 pandemic and the same period of time in 2019 at our institution. A 50% reduction of surgical procedures during th...
covid-19 pandemic;orthopedic surgery;sarscov-2;spinal surgery;trauma patients
Journal Article
Tamburrelli, Francesco Ciro;Meluzio, Maria Concetta;Perna, Andrea;Santagada, Domenico Alessandro;Genitiempo, Maurizio;Zirio, Gianfranco;Proietti, Luca
10.1016/j.jor.2020.06.014
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Spinal surgery in COVID-19 pandemic era: One trauma hub center experience in central-southern Italy. [Abstract]: The aim of the study is to analyze and report the results of the surgical activity in a spinal unit of a trauma hub in central Italy during COVID-19 pandemic. Surgical activity was compared between ...
32,366,740
Am J Ther
COVID-19 and Avoiding Ibuprofen. How Good Is the Evidence?
Ibuprofen is an over-the-counter medication that is used widely for the treatment of pain and fever during COVID-19 pandemic. A concern was raised regarding the safety of ibuprofen use because of its role in increasing ACE2 levels within the Renin-Angiotensin-Aldosterone system. ACE2 is the coreceptor for the entry of ...
Journal Article
Kutti Sridharan, Gurusaravanan;Kotagiri, Rajesh;Chandiramani, Vijay H;Mohan, Babu P;Vegunta, Rathnamitreyee;Vegunta, Radhakrishna;Rokkam, Venkata R P
10.1097/MJT.0000000000001196
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: COVID-19 and Avoiding Ibuprofen. How Good Is the Evidence? [Abstract]: Ibuprofen is an over-the-counter medication that is used widely for the treatment of pain and fever during COVID-19 pandemic. A concern was raised regarding the safety of ibuprofen use because of its role in increasing ACE2 levels within th...
32,797,067
PLoS One
Mask or no mask for COVID-19: A public health and market study.
Efficient strategies to contain the coronavirus disease 2019 (COVID-19) pandemic are peremptory to relieve the negatively impacted public health and global economy, with the full scope yet to unfold. In the absence of highly effective drugs, vaccines, and abundant medical resources, many measures are used to manage the...
Journal Article
Li, Tom;Liu, Yan;Li, Man;Qian, Xiaoning;Dai, Susie Y
10.1371/journal.pone.0237691
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Mask or no mask for COVID-19: A public health and market study. [Abstract]: Efficient strategies to contain the coronavirus disease 2019 (COVID-19) pandemic are peremptory to relieve the negatively impacted public health and global economy, with the full scope yet to unfold. In the absence of highly effective ...
32,778,849
J Arrhythm
Syncope, Brugada syndrome, and COVID-19 lung disease.
A 52-year-old male with no history of familiar sudden death arrived at our Emergency Department after syncope with loss of consciousness occurred during high fever. The thoracic high-resolution computed tomography demonstrated bilateral multiple ground-glass opacities. The nose-pharyngeal swab resulted positive for SAR...
brugada syndrome;covid-19 lung disease;fever
Case Reports
Pasquetto, Giampaolo;Conti, Giovanni Battista;Susana, Angela;Leone, Lucia Anna;Bertaglia, Emanuele
10.1002/joa3.12375
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Syncope, Brugada syndrome, and COVID-19 lung disease. [Abstract]: A 52-year-old male with no history of familiar sudden death arrived at our Emergency Department after syncope with loss of consciousness occurred during high fever. The thoracic high-resolution computed tomography demonstrated bilateral multiple...
32,754,000
Paediatr Child Health
Rethinking 'essential' and 'nonessential': the developmental paediatrician's COVID-19 response.
While terms such as 'essential' and 'nonessential' used amidst the COVID-19 pandemic may serve a practical purpose, they also pose a risk of obstructing our view of the harmful indirect health consequences of this crisis. SARS-CoV-2 cases and deaths in children are minimal compared to adults, but the pandemic impacts o...
child behaviour;covid-19;child development;coronavirus;pandemics
Journal Article
Fung, Alastair;Ricci, M Florencia
10.1093/pch/pxaa077
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Rethinking 'essential' and 'nonessential': the developmental paediatrician's COVID-19 response. [Abstract]: While terms such as 'essential' and 'nonessential' used amidst the COVID-19 pandemic may serve a practical purpose, they also pose a risk of obstructing our view of the harmful indirect health consequenc...
32,838,135
SN Compr Clin Med
Clinical Management of Adult Coronavirus Infection Disease 2019 (COVID-19) Positive in the Setting of Low and Medium Intensity of Care: a Short Practical Review.
Coronavirus disease 2019 (COVID-2019) is a viral infection which is rapidly spreading on a global scale and causing a severe acute respiratory syndrome that affects today about four and a half million registered cases of people around the world. The aim of this narrative review is to provide an urgent guidance for the ...
covid-19;low-medium intensity of care;management;therapy
Journal Article;Review
Pennica, Alfredo;Conforti, Giulia;Falangone, Francesca;Martocchia, Antonio;Tafaro, Laura;Sentimentale, Alberto;Marini, Valentina;Pezzuto, Aldo;Spuntarelli, Valerio;Martelletti, Paolo
10.1007/s42399-020-00333-w
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Clinical Management of Adult Coronavirus Infection Disease 2019 (COVID-19) Positive in the Setting of Low and Medium Intensity of Care: a Short Practical Review. [Abstract]: Coronavirus disease 2019 (COVID-2019) is a viral infection which is rapidly spreading on a global scale and causing a severe acute respir...
32,517,786
Adv Rheumatol
Revisiting hydroxychloroquine and chloroquine for patients with chronic immunity-mediated inflammatory rheumatic diseases.
Hydroxychloroquine and chloroquine, also known as antimalarial drugs, are widely used in the treatment of rheumatic diseases and have recently become the focus of attention because of the ongoing COVID-19 pandemic. Rheumatologists have been using antimalarials to manage patients with chronic immune-mediated inflammator...
antimalarials;chloroquine;chronic immune-mediated inflammatory rheumatic diseases;hydroxychloroquine
Journal Article;Systematic Review
Dos Reis Neto, Edgard Torres;Kakehasi, Adriana Maria;de Medeiros Pinheiro, Marcelo;Ferreira, Gilda Aparecida;Marques, Claudia Diniz Lopes;da Mota, Licia Maria Henrique;Dos Santos Paiva, Eduardo;Pileggi, Gecilmara Cristina Salviato;Sato, Emilia Inoue;Reis, Ana Paula Monteiro Gomides;Xavier, Ricardo Machado;Provenza, Jos...
10.1186/s42358-020-00134-8
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Revisiting hydroxychloroquine and chloroquine for patients with chronic immunity-mediated inflammatory rheumatic diseases. [Abstract]: Hydroxychloroquine and chloroquine, also known as antimalarial drugs, are widely used in the treatment of rheumatic diseases and have recently become the focus of attention bec...
32,427,569
Orv Hetil
Opportunity of periodic monitoring of COVID-19 patients, asymptomatic virus carriers, and postinfectious individuals with IgM/IgG rapid antibody tests among healthcare workers during SARS-CoV-2 pandemic.
The first Hungarian COVID-19 case was reported on March 4, 2020 by Hungarian officials. Healthcare workers (HCWs) are at the highest risk of contracting the novel coronavirus (SARS-CoV-2), with 12% of total coronavirus cases confirmed among them recently. 80% of the infected persons show only mild, moderate symptoms or...
covid-19;covid-19;igm/igg gyorstesztek covid-19-kimutatasra;rt-pcr;sars-cov-2;egeszsegugyi dolgozok;epidemic;healthcare workers;jarvany;pandemic;pandemia;rapid antibody tests for covid-19;vilagjarvany
Journal Article
Rago, Zsuzsanna;Szijjarto, Laszlo;Duda, Erno;Bella, Zsolt
10.1556/650.2020.31862
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Opportunity of periodic monitoring of COVID-19 patients, asymptomatic virus carriers, and postinfectious individuals with IgM/IgG rapid antibody tests among healthcare workers during SARS-CoV-2 pandemic. [Abstract]: The first Hungarian COVID-19 case was reported on March 4, 2020 by Hungarian officials. Healthc...
32,392,562
Int Arch Allergy Immunol
JAK Inhibition as a New Treatment Strategy for Patients with COVID-19.
After the advent of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the outbreak of coronavirus disease 2019 (COVID-19) commenced across the world. Understanding the Immunopathogenesis of COVID-19 is essential for interrupting viral infectivity and preventing aberrant immune responses before a vaccine can...
angiotensin receptor blocker;angiotensin-converting enzyme inhibitor;bricitinib;cytokine;jak inhibitors;jak-stat pathway;methotrexate
Journal Article;Review
Seif, Farhad;Aazami, Hossein;Khoshmirsafa, Majid;Kamali, Monireh;Mohsenzadegan, Monireh;Pornour, Majid;Mansouri, Davood
10.1159/000508247
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: JAK Inhibition as a New Treatment Strategy for Patients with COVID-19. [Abstract]: After the advent of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the outbreak of coronavirus disease 2019 (COVID-19) commenced across the world. Understanding the Immunopathogenesis of COVID-19 is essential for ...
32,964,919
Clin Infect Dis
SARS-CoV-2 transmission dynamics should inform policy.
It is generally agreed that striking a balance between resuming economic and social activities and keeping the effective reproductive number (R0) below 1 using non-pharmaceutical interventions is an important goal until and even after effective vaccines become available. Therefore, the need remains to understand how th...
covid-19;sars-cov-2;coronavirus;novel coronavirus;transmission
Journal Article
Cevik, Muge;Marcus, Julia L;Buckee, Caroline;Smith, Tara C
10.1093/cid/ciaa1442
[ 0, 0, 1, 0, 1, 0, 0 ]
[Title]: SARS-CoV-2 transmission dynamics should inform policy. [Abstract]: It is generally agreed that striking a balance between resuming economic and social activities and keeping the effective reproductive number (R0) below 1 using non-pharmaceutical interventions is an important goal until and even after effective...
32,454,983
J Pharm Policy Pract
Sterilization plan of the used metered dose inhalers (MDI) to avoid wastage amid COVID-19 pandemic drug shortage.
Background Coronavirus is causing a shortage of critical inhalers needed by patients with Asthma and respiratory illness. Patients with Asthma are at higher risk if they tract the novel Coronavirus. As the coronavirus continues to spread, hospitals are turning to use more salbutamol MDI. Salbutamol MDI has become the l...
covid-19;drug shortage;metered dse inhalers (mdi);sterilization
Journal Article
Elbeddini, Ali
10.1186/s40545-020-00224-4
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Sterilization plan of the used metered dose inhalers (MDI) to avoid wastage amid COVID-19 pandemic drug shortage. [Abstract]: Background Coronavirus is causing a shortage of critical inhalers needed by patients with Asthma and respiratory illness. Patients with Asthma are at higher risk if they tract the novel...
32,908,840
Eur J Case Rep Intern Med
COVID-19 in a Patient with Accidental Drug-Induced Neutropenia.
Background: Coronavirus disease 2019 (COVID-19) presents with a wide range of illness severity, from asymptomatic disease to severe acute respiratory distress syndrome (ARDS). Immunosuppression is considered a risk factor for severe COVID-19, but there are only few reports on disease progression in immunocompromised pa...
covid-19;clinical course;neutropenia;pneumectomy
Journal Article
Meyre, Pascal B;Radosavac, Milos;Baumann, Lukas;Piso, Rein Jan;Hoffmann, Matthias
10.12890/2020_001848
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: COVID-19 in a Patient with Accidental Drug-Induced Neutropenia. [Abstract]: Background: Coronavirus disease 2019 (COVID-19) presents with a wide range of illness severity, from asymptomatic disease to severe acute respiratory distress syndrome (ARDS). Immunosuppression is considered a risk factor for severe CO...
32,656,359
BMJ Open Ophthalmol
Differences in SARS-CoV-2 recommendations from major ophthalmology societies worldwide.
Objective: Since the WHO declared the COVID-19 outbreak as a public health emergency, medical societies around the world published COVID-19 recommendations to physicians to ensure patient care and physician safety. During this pandemic, ophthalmologists around the world adapted their clinical and surgical practice foll...
medical education;public health;telemedicine;treatment other
Journal Article
Nguyen, Anne X;Gervasio, Kalla A;Wu, Albert Y
10.1136/bmjophth-2020-000525
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Differences in SARS-CoV-2 recommendations from major ophthalmology societies worldwide. [Abstract]: Objective: Since the WHO declared the COVID-19 outbreak as a public health emergency, medical societies around the world published COVID-19 recommendations to physicians to ensure patient care and physician safe...
32,875,060
Int J Cardiol Heart Vasc
Angiotensin-converting enzyme inhibitors and angiotensin-receptor blockers and the risk of COVID-19 infection or severe disease: Systematic review and meta-analysis.
Objective: Animal studies suggested that angiotensin-converting enzyme inhibitors (ACEi) and angiotensin-receptor blockers (ARB) facilitate the inoculation of potentially leading to a higher risk of infection and/or disease severity. We aimed to systematically evaluate the risk of COVID-19 infection and the risk of sev...
acute lung injury;acute respiratory distress syndrome;angiotensin-converting enzyme inhibitor;angiotensin-receptor blocker;coronavirus;sars-cov-2
Journal Article
Caldeira, Daniel;Alves, Mariana;Gouveia E Melo, Ryan;Silverio Antonio, Pedro;Cunha, Nelson;Nunes-Ferreira, Afonso;Prada, Luisa;Costa, Joao;Pinto, Fausto J
10.1016/j.ijcha.2020.100627
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Angiotensin-converting enzyme inhibitors and angiotensin-receptor blockers and the risk of COVID-19 infection or severe disease: Systematic review and meta-analysis. [Abstract]: Objective: Animal studies suggested that angiotensin-converting enzyme inhibitors (ACEi) and angiotensin-receptor blockers (ARB) faci...
32,864,588
EClinicalMedicine
Clinical features, diagnostics, and outcomes of patients presenting with acute respiratory illness: A retrospective cohort study of patients with and without COVID-19.
Background: Most data on the clinical presentation, diagnostics, and outcomes of patients with COVID-19 have been presented as case series without comparison to patients with other acute respiratory illnesses. Methods: We examined emergency department patients between February 3 and March 31, 2020 with an acute respira...
Journal Article
Shah, Sachin J;Barish, Peter N;Prasad, Priya A;Kistler, Amy;Neff, Norma;Kamm, Jack;Li, Lucy M;Chiu, Charles Y;Babik, Jennifer M;Fang, Margaret C;Abe-Jones, Yumiko;Alipanah, Narges;Alvarez, Francisco N;Botvinnik, Olga Borisovna;Castaneda, Gloria;Dadasovich, Rand M;Davis, Jennifer;Deng, Xianding;DeRisi, Joseph L;Detweile...
10.1016/j.eclinm.2020.100518
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Clinical features, diagnostics, and outcomes of patients presenting with acute respiratory illness: A retrospective cohort study of patients with and without COVID-19. [Abstract]: Background: Most data on the clinical presentation, diagnostics, and outcomes of patients with COVID-19 have been presented as case...
32,718,125
Turk J Med Sci
Hepatitis A susceptibility parallels high COVID-19 mortality.
The COVID-19 has become the biggest health problem of our century. We hypothesized that immunity against Hepatitis A virus (HAV) may provide protection from COVID- 19. As of June 10, 2020, the infection had spread to 213 countries, with 7.3 million people infected and 413,733 dead . We combined this data with the WHO's...
covid-19;hepatitis a;immunity;vaccine
Letter
SarialIoGlu, FaIk;Belen, Fatma Burcu;Hayran, KadIr Mutlu
10.3906/sag-2007-133
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Hepatitis A susceptibility parallels high COVID-19 mortality. [Abstract]: The COVID-19 has become the biggest health problem of our century. We hypothesized that immunity against Hepatitis A virus (HAV) may provide protection from COVID- 19. As of June 10, 2020, the infection had spread to 213 countries, with ...
32,708,196
Int J Mol Sci
A Comprehensive Mapping of the Druggable Cavities within the SARS-CoV-2 Therapeutically Relevant Proteins by Combining Pocket and Docking Searches as Implemented in Pockets 2.0.
(1) Background: Virtual screening studies on the therapeutically relevant proteins of the severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) require a detailed characterization of their druggable binding sites, and, more generally, a convenient pocket mapping represents a key step for structure-based in silic...
sars-cov-2;blind docking;docking simulations;pocket druggability;pocket search;virtual screening
Journal Article
Gervasoni, Silvia;Vistoli, Giulio;Talarico, Carmine;Manelfi, Candida;Beccari, Andrea R;Studer, Gabriel;Tauriello, Gerardo;Waterhouse, Andrew Mark;Schwede, Torsten;Pedretti, Alessandro
10.3390/ijms21145152
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: A Comprehensive Mapping of the Druggable Cavities within the SARS-CoV-2 Therapeutically Relevant Proteins by Combining Pocket and Docking Searches as Implemented in Pockets 2.0. [Abstract]: (1) Background: Virtual screening studies on the therapeutically relevant proteins of the severe acute respiratory syndro...
32,536,457
Arch Med Res
Should We Try SARS-CoV-2 Helicase Inhibitors for COVID-19 Therapy?
The discovery of new drugs for treating the new coronavirus (SARS-CoV-2) or repurposing those already in use for other viral infections is possible through understanding of the viral replication cycle and pathogenicity. This article highlights the advantage of targeting one of the non-structural proteins, helicase (nsp...
covid-19;helicase;sars-cov-2
Journal Article
Habtemariam, Solomon;Nabavi, Seyed Fazel;Banach, Maciej;Berindan-Neagoe, Ioana;Sarkar, Kasturi;Sil, Parames C;Nabavi, Seyed Mohammad
10.1016/j.arcmed.2020.05.024
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Should We Try SARS-CoV-2 Helicase Inhibitors for COVID-19 Therapy? [Abstract]: The discovery of new drugs for treating the new coronavirus (SARS-CoV-2) or repurposing those already in use for other viral infections is possible through understanding of the viral replication cycle and pathogenicity. This article...
32,881,845
MMWR Morb Mortal Wkly Rep
Hydroxychloroquine and Chloroquine Prescribing Patterns by Provider Specialty Following Initial Reports of Potential Benefit for COVID-19 Treatment - United States, January-June 2020.
Hydroxychloroquine and chloroquine, primarily used to treat autoimmune diseases and to prevent and treat malaria, received national attention in early March 2020, as potential treatment and prophylaxis for coronavirus disease 2019 (COVID-19) (1). On March 20, the Food and Drug Administration (FDA) issued an emergency u...
Journal Article
Bull-Otterson, Lara;Gray, Elizabeth B;Budnitz, Daniel S;Strosnider, Heather M;Schieber, Lyna Z;Courtney, Joseph;Garcia, Macarena C;Brooks, John T;Mac Kenzie, William R;Gundlapalli, Adi V
10.15585/mmwr.mm6935a4
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Hydroxychloroquine and Chloroquine Prescribing Patterns by Provider Specialty Following Initial Reports of Potential Benefit for COVID-19 Treatment - United States, January-June 2020. [Abstract]: Hydroxychloroquine and chloroquine, primarily used to treat autoimmune diseases and to prevent and treat malaria, r...
33,042,442
Am J Transl Res
Transcription factor-mediated signaling pathways' contribution to the pathology of acute lung injury and acute respiratory distress syndrome.
The 2019 novel coronavirus (2019-nCoV) is still spreading rapidly around the world, and one cause of lethality for patients infected with 2019-nCoV is acute respiratory distress syndrome (ARDS). ARDS is a severe syndrome of acute lung injury (ALI) that is predominantly triggered by inflammation and results in a sudden ...
ali;ap-1;inflammation;nf-kappab;wnt/beta-catenin;transcriptional regulation
Journal Article
Chen, Zhi;Hua, Shan
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Transcription factor-mediated signaling pathways' contribution to the pathology of acute lung injury and acute respiratory distress syndrome. [Abstract]: The 2019 novel coronavirus (2019-nCoV) is still spreading rapidly around the world, and one cause of lethality for patients infected with 2019-nCoV is acute ...
33,048,823
J Med Internet Res
The Twitter Social Mobility Index: Measuring Social Distancing Practices With Geolocated Tweets.
BACKGROUND: Social distancing is an important component of the response to the COVID-19 pandemic. Minimizing social interactions and travel reduces the rate at which the infection spreads and "flattens the curve" so that the medical system is better equipped to treat infected individuals. However, it remains unclear ho...
covid-19;twitter;index;mobility;social distancing;social media;surveillance;tracking;travel
Journal Article
Xu, Paiheng;Dredze, Mark;Broniatowski, David A
10.2196/21499
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: The Twitter Social Mobility Index: Measuring Social Distancing Practices With Geolocated Tweets. [Abstract]: BACKGROUND: Social distancing is an important component of the response to the COVID-19 pandemic. Minimizing social interactions and travel reduces the rate at which the infection spreads and "flattens ...
32,495,952
Dermatol Ther
Recommendations for treatment of nail psoriasis during the COVID-19 pandemic.
The novel coronavirus disease 2019 (COVID-19) pandemic has resulted in a paradigm shift in disease management. Since immunosuppression may cause increased susceptibility to COVID-19, there is uncertainty as to whether systemically treated nail psoriasis patients are at increased infection risk. While specific data on n...
covid-19;sars-cov-2;biologics;immunosuppression;nail disorders;nail psoriasis;psoriasis
Journal Article;Review
Ricardo, Jose W;Lipner, Shari R
10.1111/dth.13757
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Recommendations for treatment of nail psoriasis during the COVID-19 pandemic. [Abstract]: The novel coronavirus disease 2019 (COVID-19) pandemic has resulted in a paradigm shift in disease management. Since immunosuppression may cause increased susceptibility to COVID-19, there is uncertainty as to whether sys...
33,064,680
Bol Med Hosp Infant Mex
SARS-CoV-2 and influenza: a comparative overview and treatment implications.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and Alphainfluenzavirus are RNA viruses that cause coronavirus disease-19 and influenza, respectively. Both viruses infect the respiratory tract, show similar symptoms, and use surface proteins to infect the host. Influenza requires hemagglutinin and neuramin...
covid-19;coronavirus disease-19;influenza;sars-cov-2;severe acute respiratory syndrome coronavirus 2
Journal Article;Review
Manzanares-Meza, Laura D;Medina-Contreras, Oscar
10.24875/BMHIM.20000183
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: SARS-CoV-2 and influenza: a comparative overview and treatment implications. [Abstract]: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and Alphainfluenzavirus are RNA viruses that cause coronavirus disease-19 and influenza, respectively. Both viruses infect the respiratory tract, show similar sy...
32,512,673
Turk J Med Sci
COVID-19: pathogenesis, genetic polymorphism, clinical features and laboratory findings
COVID-19 caused by a novel agent SARS-CoV-2 progressed to a pandemic condition and resulted in a major public health concern worldwide, leading to social and economic issues at the same time. The pathogenesis of COVID-19 starts with the bonding of the virus to ACE2 receptors expressed in many tissues, and the triggered...
covid-19;sars-cov-2;clinical features;genetic polymorphism;laboratory findings;pathogenesis;genetic polymorphism;laboratory findings
Journal Article;Review
Ozturk, Recep;Tasova, Yesim;Ayaz, Akif
10.3906/sag-2005-287
[ 0, 1, 0, 1, 0, 0, 0 ]
[Title]: COVID-19: pathogenesis, genetic polymorphism, clinical features and laboratory findings [Abstract]: COVID-19 caused by a novel agent SARS-CoV-2 progressed to a pandemic condition and resulted in a major public health concern worldwide, leading to social and economic issues at the same time. The pathogenesis of...
32,685,143
Ann Med Surg (Lond)
A mathematical model to guide the re-opening of economies during the COVID-19 pandemic.
Despite rigorous global containment and quarantine efforts, the incidence of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), also known as COVID-19, continues to surge, with more than 12 million laboratory-confirmed cases and over 500,000 deaths worldwide (as of 11 July 2020). Aside from the continued...
coronavirus;economy;health;lockdown;model;norms
Journal Article
Noorbhai, Habib
10.1016/j.amsu.2020.06.041
[ 0, 0, 1, 0, 0, 1, 0 ]
[Title]: A mathematical model to guide the re-opening of economies during the COVID-19 pandemic. [Abstract]: Despite rigorous global containment and quarantine efforts, the incidence of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), also known as COVID-19, continues to surge, with more than 12 millio...
32,438,868
Emerg Microbes Infect
ddPCR: a more accurate tool for SARS-CoV-2 detection in low viral load specimens.
Quantitative real time PCR (RT-PCR) is widely used as the gold standard for clinical detection of SARS-CoV-2. However, due to the low viral load specimens and the limitations of RT-PCR, significant numbers of false negative reports are inevitable, which results in failure to timely diagnose, cut off transmission, and a...
rt-pcr;sars-cov-2;clinical detection;droplet digital pcr;false negative
Journal Article
Suo, Tao;Liu, Xinjin;Feng, Jiangpeng;Guo, Ming;Hu, Wenjia;Guo, Dong;Ullah, Hafiz;Yang, Yang;Zhang, Qiuhan;Wang, Xin;Sajid, Muhanmmad;Huang, Zhixiang;Deng, Liping;Chen, Tielong;Liu, Fang;Xu, Ke;Liu, Yuan;Zhang, Qi;Liu, Yingle;Xiong, Yong;Chen, Guozhong;Lan, Ke;Chen, Yu
10.1080/22221751.2020.1772678
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: ddPCR: a more accurate tool for SARS-CoV-2 detection in low viral load specimens. [Abstract]: Quantitative real time PCR (RT-PCR) is widely used as the gold standard for clinical detection of SARS-CoV-2. However, due to the low viral load specimens and the limitations of RT-PCR, significant numbers of false ne...
32,721,809
Med Hypotheses
Kawasaki-like disease in children with COVID-19: A hypothesis.
With rapid spread of severe acute respiratory syndrome- corona virus-2 (SARS-COV-2) globally, some new aspects of the disease have been reported. Recently, it has been reported the incidence of Kawasaki-like disease among children with COVID-19. Since, children had been known to be less severely affected by the virus i...
ace2 receptor;downregulation;kawasaki disease;kawasaki-like disease;sars-cov2;tnf- alpha
Letter
Amirfakhryan, Hamideh
10.1016/j.mehy.2020.110117
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Kawasaki-like disease in children with COVID-19: A hypothesis. [Abstract]: With rapid spread of severe acute respiratory syndrome- corona virus-2 (SARS-COV-2) globally, some new aspects of the disease have been reported. Recently, it has been reported the incidence of Kawasaki-like disease among children with ...
33,033,173
Sci Immunol
Persistence of serum and saliva antibody responses to SARS-CoV-2 spike antigens in COVID-19 patients.
While the antibody response to SARS-CoV-2 has been extensively studied in blood, relatively little is known about the antibody response in saliva and its relationship to systemic antibody levels. Here, we profiled by enzyme-linked immunosorbent assays (ELISAs) IgG, IgA and IgM responses to the SARS-CoV-2 spike protein ...
Journal Article;Observational Study;Research Support, Non-U.S. Gov't
Isho, Baweleta;Abe, Kento T;Zuo, Michelle;Jamal, Alainna J;Rathod, Bhavisha;Wang, Jenny H;Li, Zhijie;Chao, Gary;Rojas, Olga L;Bang, Yeo Myong;Pu, Annie;Christie-Holmes, Natasha;Gervais, Christian;Ceccarelli, Derek;Samavarchi-Tehrani, Payman;Guvenc, Furkan;Budylowski, Patrick;Li, Angel;Paterson, Aimee;Yue, Feng Yun;Mari...
10.1126/sciimmunol.abe5511
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Persistence of serum and saliva antibody responses to SARS-CoV-2 spike antigens in COVID-19 patients. [Abstract]: While the antibody response to SARS-CoV-2 has been extensively studied in blood, relatively little is known about the antibody response in saliva and its relationship to systemic antibody levels. H...
32,833,661
JMIR Public Health Surveill
Consumer Reported Care Deferrals Due to the COVID-19 Pandemic, and the Role and Potential of Telemedicine: Cross-Sectional Analysis.
BACKGROUND: The COVID-19 pandemic forced many health systems to proactively reduce care delivery to prepare for an expected surge in hospitalizations. There have been concerns that care deferral may have negative health effects, but it is hoped that telemedicine can provide a viable alternative. OBJECTIVE: This study a...
covid-19;alternative;deferred care;health effect;mental health;telemedicine;viability
Journal Article
Atherly, Adam;Van Den Broek-Altenburg, Eline;Hart, Victoria;Gleason, Kelsey;Carney, Jan
10.2196/21607
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Consumer Reported Care Deferrals Due to the COVID-19 Pandemic, and the Role and Potential of Telemedicine: Cross-Sectional Analysis. [Abstract]: BACKGROUND: The COVID-19 pandemic forced many health systems to proactively reduce care delivery to prepare for an expected surge in hospitalizations. There have been...
32,754,313
Ann Med Surg (Lond)
Impact of COVID-19 pandemic on residency and fellowship training programs in Saudi Arabia: A nationwide cross-sectional study.
Background: Coronavirus disease 2019 (COVID-19) has profoundly impacted residency and fellowship training and education. However, how and to what extent the daily involvement of trainees in clinical and surgical activities was compromised by the COVID-19 pandemic is currently unknown. Materials and methods: We conducte...
covid-19;fellowship training;pandemic;residency training;saudi arabia;survey
Journal Article
Balhareth, Ameera;AlDuhileb, Mohammed Abdulrazzaq;Aldulaijan, Fozan A;Aldossary, Mohammed Yousef
10.1016/j.amsu.2020.07.025
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Impact of COVID-19 pandemic on residency and fellowship training programs in Saudi Arabia: A nationwide cross-sectional study. [Abstract]: Background: Coronavirus disease 2019 (COVID-19) has profoundly impacted residency and fellowship training and education. However, how and to what extent the daily involveme...
32,837,779
World Med Health Policy
Racial Disparities in COVID-19 Mortality Among Essential Workers in the United States.
Racial disparities are apparent in the impact of coronavirus disease 2019 (COVID-19) in the United States, yet the factors contributing to racial inequities in COVID-19 mortality remain controversial. To better understand these factors, we investigated racial disparities in COVID-19 mortality among America's essential ...
coronavirus;health status disparities;infectious diseases;occupational health;race factors;viral transmission
Journal Article
Rogers, Tiana N;Rogers, Charles R;VanSant-Webb, Elizabeth;Gu, Lily Y;Yan, Bin;Qeadan, Fares
10.1002/wmh3.358
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Racial Disparities in COVID-19 Mortality Among Essential Workers in the United States. [Abstract]: Racial disparities are apparent in the impact of coronavirus disease 2019 (COVID-19) in the United States, yet the factors contributing to racial inequities in COVID-19 mortality remain controversial. To better u...
32,845,145
J Med Chem
Chinese Therapeutic Strategy for Fighting COVID-19 and Potential Small-Molecule Inhibitors against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2).
The coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to more than 20 million people infected worldwide with an average mortality rate of 3.6%. This virus poses major challenges to public health, as it not only is highly contagious but also can be transmi...
Journal Article;Research Support, Non-U.S. Gov't;Review
Choudhry, Namrta;Zhao, Xin;Xu, Dan;Zanin, Mark;Chen, Weisan;Yang, Zifeng;Chen, Jianxin
10.1021/acs.jmedchem.0c00626
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Chinese Therapeutic Strategy for Fighting COVID-19 and Potential Small-Molecule Inhibitors against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). [Abstract]: The coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to more than 20 mil...
32,978,729
Mol Neurobiol
Neurological Complications Associated with the Blood-Brain Barrier Damage Induced by the Inflammatory Response During SARS-CoV-2 Infection.
The main discussion above of the novel pathogenic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has focused substantially on the immediate risks and impact on the respiratory system; however, the effects induced to the central nervous system are currently unknown. Some authors have suggested th...
blood-brain barrier;covid-19;inflammatory response;neurological complications;neurotropism;sars-cov-2
Journal Article;Review
Alquisiras-Burgos, Ivan;Peralta-Arrieta, Irlanda;Alonso-Palomares, Luis Antonio;Zacapala-Gomez, Ana Elvira;Salmeron-Barcenas, Eric Genaro;Aguilera, Penelope
10.1007/s12035-020-02134-7
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: Neurological Complications Associated with the Blood-Brain Barrier Damage Induced by the Inflammatory Response During SARS-CoV-2 Infection. [Abstract]: The main discussion above of the novel pathogenic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has focused substantially on the immed...
32,548,842
Tunis Med
Attitudes of health professionals towards the response to the COVID-19 pandemic in Maghreb.
OBJECTIVE: Measuring the attitudes of health professionals in two Maghreb countries (Tunisia and Algeria) with regard to the response to COVID-19 during the first quarter of 2020. METHODS: This scoping study was based on a "Google Form" covering three constituents of the response plan against COVID-19: responders, acti...
Journal Article
Ben Abdelaziz, Ahmed;Benzarti, Sofien;Nouira, Sarra;Mlouki, Imen;Achouri, Mohamed Yacine;Ben Abdelaziz, Islem;Yahia, Faten;Barhoumi, Tarek;Soulimane, Abdelkrim
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Attitudes of health professionals towards the response to the COVID-19 pandemic in Maghreb. [Abstract]: OBJECTIVE: Measuring the attitudes of health professionals in two Maghreb countries (Tunisia and Algeria) with regard to the response to COVID-19 during the first quarter of 2020. METHODS: This scoping study...
32,349,121
Nature
Massively multiplexed nucleic acid detection with Cas13.
The great majority of globally circulating pathogens go undetected, undermining patient care and hindering outbreak preparedness and response. To enable routine surveillance and comprehensive diagnostic applications, there is a need for detection technologies that can scale to test many samples(1-3) while simultaneousl...
Journal Article;Research Support, N.I.H., Extramural;Research Support, Non-U.S. Gov't;Research Support, U.S. Gov't, Non-P.H.S.
Ackerman, Cheri M;Myhrvold, Cameron;Thakku, Sri Gowtham;Freije, Catherine A;Metsky, Hayden C;Yang, David K;Ye, Simon H;Boehm, Chloe K;Kosoko-Thoroddsen, Tinna-Solveig F;Kehe, Jared;Nguyen, Tien G;Carter, Amber;Kulesa, Anthony;Barnes, John R;Dugan, Vivien G;Hung, Deborah T;Blainey, Paul C;Sabeti, Pardis C
10.1038/s41586-020-2279-8
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Massively multiplexed nucleic acid detection with Cas13. [Abstract]: The great majority of globally circulating pathogens go undetected, undermining patient care and hindering outbreak preparedness and response. To enable routine surveillance and comprehensive diagnostic applications, there is a need for detec...
32,883,010
Vision (Basel)
Potential of Ocular Transmission of SARS-CoV-2: A Review.
PURPOSE OF REVIEW: to provide a prospective on the current mechanisms by which SARS-CoV-2 enters cells and replicates, and its implications for ocular transmission. The literature was analyzed to understand ocular transmission as well as molecular mechanisms by which SARS-CoV-2 enters cells and replicates. Analysis of ...
covid-19;sars-cov-2;conjunctivitis;coronavirus;ocular transmission
Journal Article;Review
Barnett, Brad P;Wahlin, Karl;Krawczyk, Michal;Spencer, Doran;Welsbie, Derek;Afshari, Natalie;Chao, Daniel
10.3390/vision4030040
[ 0, 0, 0, 1, 1, 0, 0 ]
[Title]: Potential of Ocular Transmission of SARS-CoV-2: A Review. [Abstract]: PURPOSE OF REVIEW: to provide a prospective on the current mechanisms by which SARS-CoV-2 enters cells and replicates, and its implications for ocular transmission. The literature was analyzed to understand ocular transmission as well as mol...
33,011,308
J Hosp Infect
Providing essential clinical care for non-COVID-19 patients in a Seoul metropolitan acute care hospital amidst ongoing treatment of COVID-19 patients.
We assessed infection control efforts by comparing data collected over 20 weeks during a pandemic under a dual-track healthcare system. A decline in non-COVID-19 patients visiting the emergency department by 37.6% (P<0.01) was observed since admitting COVID-19 cases. However, patients with acute myocardial infarction (...
acute care hospital;covid-19;essential clinical care;hospital infection;hospital visiting;non-covid-19 patients
Comparative Study;Journal Article
Lee, K D;Lee, S B;Lim, J K;Kang, Y M;Kim, I B;Moon, H J;Lee, W J
10.1016/j.jhin.2020.09.031
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: Providing essential clinical care for non-COVID-19 patients in a Seoul metropolitan acute care hospital amidst ongoing treatment of COVID-19 patients. [Abstract]: We assessed infection control efforts by comparing data collected over 20 weeks during a pandemic under a dual-track healthcare system. A decline in...
32,904,923
Brain Behav Immun Health
Acute encephalopathy is associated with worse outcomes in COVID-19 patients.
Background: Acute encephalopathy with COVID-19 has been reported in several studies but its impact on outcomes remains unclear. We hypothesized that hospitalized COVID-19 patients with encephalopathy have worse COVID-19 related outcomes. Methods: We used TriNetX, with a large COVID-19 database, collecting real-time ele...
covid-19;encephalopathy;outcomes
Journal Article
Shah, Vishank Arun;Nalleballe, Krishna;Zaghlouleh, Mhd Ezzat;Onteddu, Sanjeeva
10.1016/j.bbih.2020.100136
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Acute encephalopathy is associated with worse outcomes in COVID-19 patients. [Abstract]: Background: Acute encephalopathy with COVID-19 has been reported in several studies but its impact on outcomes remains unclear. We hypothesized that hospitalized COVID-19 patients with encephalopathy have worse COVID-19 re...
32,804,112
J Xray Sci Technol
A retrospective study of the initial chest CT imaging findings in 50 COVID-19 patients stratified by gender and age.
OBJECTIVE: To retrospectively analyze and stratify the initial clinical features and chest CT imaging findings of patients with COVID-19 by gender and age. METHODS: Data of 50 COVID-19 patients were collected in two hospitals. The clinical manifestations, laboratory examination and chest CT imaging features were analyz...
covid-19;sars-cov-2;x-ray computed tomography;analysis of ct imaging findings;novel coronavirus-infected pneumonia
Comparative Study;Journal Article
Gu, Qianbiao;Ouyang, Xin;Xie, An;Tan, Xianzheng;Liu, Jianbin;Huang, Feng;Liu, Peng
10.3233/XST-200709
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: A retrospective study of the initial chest CT imaging findings in 50 COVID-19 patients stratified by gender and age. [Abstract]: OBJECTIVE: To retrospectively analyze and stratify the initial clinical features and chest CT imaging findings of patients with COVID-19 by gender and age. METHODS: Data of 50 COVID-...
32,837,680
Boll Unione Mat Ital (2008)
Epidemic evolution models to the test of Covid-19.
We illustrate a suitable adaptation and modification of classical epidemic evolution models that proves helpful in the study of Covid-19 spread in Italy.
epidemic evolution dynamic;fitting data;iterative process;mathematical models
Journal Article
Brandi, Primo;Ceppitelli, Rita;Salvadori, Anna
10.1007/s40574-020-00252-7
[ 0, 0, 0, 0, 0, 1, 0 ]
[Title]: Epidemic evolution models to the test of Covid-19. [Abstract]: We illustrate a suitable adaptation and modification of classical epidemic evolution models that proves helpful in the study of Covid-19 spread in Italy. [Keywords]: epidemic evolution dynamic;fitting data;iterative process;mathematical models
32,834,886
J Chir Visc
[SOFFCO-MM guidelines for the resumption of bariatric and metabolic surgery during and after the Covid-19 pandemic].
Bariatric/metabolic surgery was paused during the Covid-19 pandemic. The impact of social confinement and the interruption of this surgery on the population with obesity has been underestimated, with weight gain and worsened comorbidities. Some candidates for this surgery are exposed to a high risk of mortality linked ...
bariatric surgery;covid-19;guidelines;obesity;pandemic
English Abstract;Journal Article
Kassir, R;Rebibo, L;Genser, L;Sterkers, A;Blanchet, M-C;Pattou, F;Msika, S
10.1016/j.jchirv.2020.05.002
[ 0, 0, 1, 0, 0, 0, 0 ]
[Title]: [SOFFCO-MM guidelines for the resumption of bariatric and metabolic surgery during and after the Covid-19 pandemic]. [Abstract]: Bariatric/metabolic surgery was paused during the Covid-19 pandemic. The impact of social confinement and the interruption of this surgery on the population with obesity has been und...
32,588,943
Diabetes Metab Res Rev
Obesity and diabetes as high-risk factors for severe coronavirus disease 2019 (Covid-19).
The outbreak of the coronavirus disease 2019 (Covid-19) has become an evolving worldwide health crisis. With the rising prevalence of obesity and diabetes has come an increasing awareness of their impacts on infectious diseases, including increased risk for various infections, post-infection complications and mortality...
covid-19;diabetes mellitus;obesity;severe coronavirus disease 2019
Journal Article;Review
Zhou, Yue;Chi, Jingwei;Lv, Wenshan;Wang, Yangang
10.1002/dmrr.3377
[ 1, 1, 0, 0, 0, 0, 0 ]
[Title]: Obesity and diabetes as high-risk factors for severe coronavirus disease 2019 (Covid-19). [Abstract]: The outbreak of the coronavirus disease 2019 (Covid-19) has become an evolving worldwide health crisis. With the rising prevalence of obesity and diabetes has come an increasing awareness of their impacts on i...
32,196,627
Eur Rev Med Pharmacol Sci
Point-of-Care Lung Ultrasound findings in novel coronavirus disease-19 pnemoniae: a case report and potential applications during COVID-19 outbreak.
An outbreak of a novel coronavirus disease-19 (nCoV-19) infection began in December 2019 in Wuhan, China, and now involved the whole word. Several health workers have been infected in different countries. We report the case of a young man with documented nCoV-19 infection evaluated with lung ultrasound and discuss pote...
Case Reports;Journal Article
Buonsenso, D;Piano, A;Raffaelli, F;Bonadia, N;de Gaetano Donati, K;Franceschi, F
10.26355/eurrev_202003_20549
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Point-of-Care Lung Ultrasound findings in novel coronavirus disease-19 pnemoniae: a case report and potential applications during COVID-19 outbreak. [Abstract]: An outbreak of a novel coronavirus disease-19 (nCoV-19) infection began in December 2019 in Wuhan, China, and now involved the whole word. Several hea...
32,877,383
Ann Ital Chir
Risks of COVID-19 transmission in blood and serum during surgery A prospective cross-sectional study from a single dedicated COVID-19 center.
The present pandemic caused by the SARS COV-2 coronavirus is still ongoing, although it is registered a slowdown in the spread for new cases. The main environmental route of transmission of SARS-CoV-2 is through droplets and fomites or surfaces, but there is a potential risk of virus spread also in smaller aerosols dur...
Case Reports;Journal Article
Fabbri, Nicolo;Righini, Eriminio;Cardarelli, Laura;Di Marco, Luigi;V Feo, Carlo
[ 0, 0, 1, 0, 1, 0, 0 ]
[Title]: Risks of COVID-19 transmission in blood and serum during surgery A prospective cross-sectional study from a single dedicated COVID-19 center. [Abstract]: The present pandemic caused by the SARS COV-2 coronavirus is still ongoing, although it is registered a slowdown in the spread for new cases. The main enviro...
32,868,801
Sci Rep
Signal amplification by reversible exchange for COVID-19 antiviral drug candidates.
Several drug candidates have been proposed and tested as the latest clinical treatment for coronavirus pneumonia (COVID-19). Chloroquine, hydroxychloroquine, ritonavir/lopinavir, and favipiravir are under trials for the treatment of this disease. The hyperpolarization technique has the ability to further provide a bett...
Journal Article;Research Support, Non-U.S. Gov't
Jeong, Hye Jin;Min, Sein;Chae, Heelim;Kim, Sarah;Lee, Gunwoo;Namgoong, Sung Keon;Jeong, Keunhong
10.1038/s41598-020-71282-6
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Signal amplification by reversible exchange for COVID-19 antiviral drug candidates. [Abstract]: Several drug candidates have been proposed and tested as the latest clinical treatment for coronavirus pneumonia (COVID-19). Chloroquine, hydroxychloroquine, ritonavir/lopinavir, and favipiravir are under trials for...
32,703,328
Br J Nutr
The rationale for a multi-step therapeutic approach based on antivirals, drugs and nutrients with immunomodulatory activity in patients with coronavirus-SARS2-induced disease of different severities.
In December 2019, a novel human-infecting coronavirus, named Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-2), was recognised to cause a pneumonia epidemic outbreak with different degrees of severity in Wuhan, Hubei Province in China. Since then, this epidemic has spread worldwide; in Europe, Italy has bee...
covid-19;sars;therapy;vitamins
Journal Article
Fiorino, Sirio;Zippi, Maddalena;Gallo, Claudio;Sifo, Debora;Sabbatani, Sergio;Manfredi, Roberto;Rasciti, Edoardo;Rasciti, Leonardo;Giampieri, Enrico;Corazza, Ivan;Leandri, Paolo;de Biase, Dario
10.1017/S0007114520002913
[ 1, 0, 0, 1, 0, 0, 0 ]
[Title]: The rationale for a multi-step therapeutic approach based on antivirals, drugs and nutrients with immunomodulatory activity in patients with coronavirus-SARS2-induced disease of different severities. [Abstract]: In December 2019, a novel human-infecting coronavirus, named Severe Acute Respiratory Syndrome Coro...
32,997,638
IEEE J Biomed Health Inform
A Novel Intelligent Computational Approach to Model Epidemiological Trends and Assess the Impact of Non-Pharmacological Interventions for COVID-19.
The novel coronavirus disease 2019 (COVID-19) pandemic has led to a worldwide crisis in public health. It is crucial we understand the epidemiological trends and impact of non-pharmacological interventions (NPIs), such as lockdowns for effective management of the disease and control of its spread. We develop and valida...
Journal Article;Research Support, Non-U.S. Gov't
Ren, Jinchang;Yan, Yijun;Zhao, Huimin;Ma, Ping;Zabalza, Jaime;Hussain, Zain;Luo, Shaoming;Dai, Qingyun;Zhao, Sophia;Sheikh, Aziz;Hussain, Amir;Li, Huakang
10.1109/JBHI.2020.3027987
[ 0, 0, 1, 0, 0, 1, 0 ]
[Title]: A Novel Intelligent Computational Approach to Model Epidemiological Trends and Assess the Impact of Non-Pharmacological Interventions for COVID-19. [Abstract]: The novel coronavirus disease 2019 (COVID-19) pandemic has led to a worldwide crisis in public health. It is crucial we understand the epidemiological ...
32,425,334
Mol Cell Probes
Sequence mismatch in PCR probes may mask the COVID-19 detection in Nepal.
*Most of the COVID-19 cases in Nepal are in the Southern districts of Nepal bordering India with travel histories to India.*Very few positive cases of COVID-19 are detected in Nepal which could either be due to early national lockdown.*Low PCR positivity rates could also be due to inefficiency of the PCR methods.*Whole...
coronavirus disease 2019 (covid-19);global initiative on sharing of all influenza data (gisaid);india;mutation;nepal;polymerase chain reaction
Journal Article
Rana, Divya Rsjb;Pokhrel, Nischal
10.1016/j.mcp.2020.101599
[ 0, 1, 0, 0, 0, 0, 0 ]
[Title]: Sequence mismatch in PCR probes may mask the COVID-19 detection in Nepal. [Abstract]: *Most of the COVID-19 cases in Nepal are in the Southern districts of Nepal bordering India with travel histories to India.*Very few positive cases of COVID-19 are detected in Nepal which could either be due to early national...
32,566,561
Ann Transl Med
Potential effectiveness and safety of antiviral agents in children with coronavirus disease 2019: a rapid review and meta-analysis.
Background: The COVID-19 outbreak presents a new, life-threatening disease. Our aim was to assess the potential effectiveness and safety of antiviral agents for COVID-19 in children. Methods: Electronic databases (MEDLINE, Embase, Web of Science, the Cochrane library, CBM, CNKI, and Wanfang Data) from their inception t...
antiviral agents;covid-19;children;meta-analysis;rapid review
Journal Article
Shi, Qianling;Zhou, Qi;Wang, Xia;Liao, Jing;Yu, Yang;Wang, Zijun;Lu, Shuya;Ma, Yanfang;Xun, Yangqin;Luo, Xufei;Li, Weiguo;Fukuoka, Toshio;Ahn, Hyeong Sik;Lee, Myeong Soo;Luo, Zhengxiu;Liu, Enmei;Chen, Yaolong;Li, Qubei;Yang, Kehu;Guan, Quanlin
10.21037/atm-20-3301
[ 1, 0, 0, 0, 0, 0, 0 ]
[Title]: Potential effectiveness and safety of antiviral agents in children with coronavirus disease 2019: a rapid review and meta-analysis. [Abstract]: Background: The COVID-19 outbreak presents a new, life-threatening disease. Our aim was to assess the potential effectiveness and safety of antiviral agents for COVID-...
32,571,747
Diagn Interv Imaging
Incidental diagnosis of Covid-19 pneumonia on chest computed tomography.
PURPOSE: The purpose of this study was to determine the prevalence and imaging characteristics of incidentally diagnosed COVID-19 pneumonia on computed tomography (CT). MATERIALS AND METHODS: This retrospective study was conducted between March 20th and March 31st, 2020 at Cochin hospital, Paris France. Thoracic CT exa...
covid-19 pneumonia;computed tomography;incidental findings;multidetector
Journal Article
Neveu, S;Saab, I;Dangeard, S;Bennani, S;Tordjman, M;Chassagnon, G;Revel, M-P
10.1016/j.diii.2020.05.011
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Incidental diagnosis of Covid-19 pneumonia on chest computed tomography. [Abstract]: PURPOSE: The purpose of this study was to determine the prevalence and imaging characteristics of incidentally diagnosed COVID-19 pneumonia on computed tomography (CT). MATERIALS AND METHODS: This retrospective study was condu...
32,863,191
Cardiovasc Revasc Med
Post myocardial infarction complications during the COVID-19 pandemic - A case series.
We report 4 cases of post myocardial infarction complications due to the delay in presentation during COVID-19 era. We highlighted the need for auscultating the chest for early diagnosis. Through this case series, we urge to raise awareness among cardiac patients to access healthcare despite the fear of COVID-19.
acute coronary syndrome;covid-19;percutaneous repair;ventricular septal rupture
Case Reports
Qureshi, Waqas T;Al-Drugh, Summer;Ogunsua, Adedotun;Harrington, Colleen;Aman, Wahaj;Balsam, Leora;Kar, Biswajit;Aurigemma, Gerald;Kundu, Amartya;Kaur, Nirmal;Smith, Craig;Fisher, Daniel;Rade, Jeffrey;Kakouros, Nikolaos
10.1016/j.carrev.2020.08.005
[ 0, 0, 0, 0, 0, 0, 1 ]
[Title]: Post myocardial infarction complications during the COVID-19 pandemic - A case series. [Abstract]: We report 4 cases of post myocardial infarction complications due to the delay in presentation during COVID-19 era. We highlighted the need for auscultating the chest for early diagnosis. Through this case series...