article_title stringlengths 1 1.44k | abstract stringlengths 10 22.8k | contributor stringlengths 29 38.3k | journal stringlengths 3 246 | full_text stringlengths 22 2.53M |
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Comparison of written reports of mammography, sonography and magnetic resonance mammography for preoperative evaluation of breast lesions, with special emphasis on magnetic resonance mammography | <p>Patients with abnormal breast findings (<italic>n</italic> = 413) were examined by mammography, sonography and magnetic resonance (MR) mammography; 185 invasive cancers, 38 carcinoma <italic>in situ</italic> and 254 benign tumours were confirmed histologically. Sensitivity for mammography was 83.7%, for sonography i... | <contrib id="A1" contrib-type="author"><name><surname>Malur</surname><given-names>Sabine</given-names></name><xref ref-type="aff" rid="I1">1</xref></contrib><contrib id="A2" contrib-type="author"><name><surname>Wurdinger</surname><given-names>Susanne</given-names></name><xref ref-type="aff" rid="I2">2</xref></contrib><... | Breast Cancer Research | <sec><title>Introduction</title><p>Mammography and sonography are the standard imaging techniques for detection and evaluation of breast disease [<xref ref-type="bibr" rid="B1">1</xref>]. Mammography is the most established screening modality [<xref ref-type="bibr" rid="B2">2</xref>]. Especially in young women and wome... |
BRCA1 and BRCA2 protein expressions in an ovotestis of a 46, XX true hermaphrodite | <p><italic>BRCA1</italic> and <italic>BRCA2</italic> breast cancer susceptibility genes encode proteins, the normal cellular functions of which are complex and multiple, and germ-line mutations in individuals predispose both to breast and to ovarian cancer. There is nevertheless substantial evidence linking BRCA1 and B... | <contrib id="A1" contrib-type="author"><name><surname>Bernard-Gallon</surname><given-names>Dominique J</given-names></name><xref ref-type="aff" rid="I1">1</xref></contrib><contrib id="A2" contrib-type="author"><name><surname>Déchelotte</surname><given-names>Pierre</given-names></name><xref ref-type="aff" rid="I... | Breast Cancer Research | <sec><title>Introduction</title><p>Hereditary predisposition to breast cancer can be attributed to germline mutations in the <italic>BRCA1</italic> or <italic>BRCA2</italic> breast cancer susceptibility genes [<xref ref-type="bibr" rid="B1">1</xref>]. Germline mutations in the <italic>BRCA1</italic> and <italic>BRCA2</... |
Transforming growth factors-β are not good biomarkers of chemopreventive efficacy in a preclinical breast cancer model system | <p>Using a carcinogen-initiated rat model of mammary tumorigenesis, we tested the hypothesis that transforming growth factor (TGF)-βs are useful biomarkers of chemopreventive efficacy in the breast. The chemopreventive agents tested were tamoxifen and the retinoids 9-<italic>cis</italic>-retinoic acid (9cRA) an... | <contrib id="A1" contrib-type="author"><name><surname>Zujewski</surname><given-names>JoAnne</given-names></name><xref ref-type="aff" rid="I2">2</xref></contrib><contrib id="A2" contrib-type="author"><name><surname>Vaughn-Cooke</surname><given-names>Anika</given-names></name><xref ref-type="aff" rid="I2">2</xref></contr... | Breast Cancer Research | <sec><title>Synopsis</title><sec><title>Introduction:</title><p>Chemoprevention has been defined as the use of noncytotoxic nutrients or pharmacologic agents to enhance intrinsic physiologic mechanisms that protect the organism against the development of mutant clones and their progression to malignant cancer. In a rec... |
Smoking and high-risk mammographic parenchymal patterns: a
case-control study | <sec><title>Introduction:</title><p>Overall, epidemiological studies [<xref ref-type="bibr" rid="B1">1</xref>,<xref ref-type="bibr" rid="B2">2</xref>,<xref ref-type="bibr" rid="B3">3</xref>,<xref ref-type="bibr" rid="B4">4</xref>] have
reported no substantial association between cigarette smoking and the risk of
... | <contrib id="A1" contrib-type="author"><name><surname>Sala</surname><given-names>Evis</given-names></name><xref ref-type="aff" rid="I1">1</xref><email>evis.sala@srl.cam.ac.uk</email></contrib><contrib id="A2" contrib-type="author"><name><surname>Warren</surname><given-names>Ruth</given-names></name><xref ref-type="aff"... | Breast Cancer Research | <sec><title>Introduction</title><p>Overall, epidemiological studies [<xref ref-type="bibr" rid="B1">1</xref>,<xref ref-type="bibr" rid="B2">2</xref>,<xref ref-type="bibr" rid="B3">3</xref>,<xref ref-type="bibr" rid="B4">4</xref>] have
reported no substantial association between cigarette smoking and the risk of
... |
Altered expression of estrogen receptor-α variant messenger RNAs
between adjacent normal breast and breast tumor tissues | <sec><title>Introduction:</title><p>Estrogen receptor (ER)-α and ER-β are believed to
mediate the action of estradiol in target tissues. Several ER-α and
ER-β variant messenger RNAs have been identified in both normal and
neoplastic human tissues. Most of these variants conta... | <contrib id="A1" contrib-type="author"><name><surname>Leygue</surname><given-names>Etienne</given-names></name><xref ref-type="aff" rid="I1">1</xref><email>eleygue@cc.umanitoba.ca</email></contrib><contrib id="A2" contrib-type="author"><name><surname>Dotzlaw</surname><given-names>Helmut</given-names></name><xref ref-ty... | Breast Cancer Research | <sec><title>Introduction</title><p>Estrogen receptor (ER)-α and ER-β are believed to mediate
the action of estradiol in target tissues [<xref ref-type="bibr" rid="B1">1</xref>,<xref ref-type="bibr" rid="B2">2</xref>]. These two receptors, which belong to the steroid/retinoic
acid/thyroid recepto... |
The Million Women Study: design and characteristics of the study population | <sec><title>Objectives:</title><p>To describe the design of the Million Women Study and the characteristics of the study population.</p></sec><sec><title>Study design:</title><p>Population-based cohort study of women aged 50-64 in the UK.</p></sec><sec><title>Setting:</title><p>Women are asked to join the Million Women... | <contrib id="A1" contrib-type="author"><collab>The Million Women Study Collaborative Group</collab><xref ref-type="aff" rid="I1">1</xref></contrib> | Breast Cancer Research | <sec><title>Introduction</title><p>The Million Women Study is a nationwide collaborative research project in the UK, the chief aim of which is to describe the relationship between use of hormone replacement therapy (HRT) and the risk of various conditions, particularly breast cancer. The study began in May 1996 and the... |
"Glutathione S-transferase M1 null genotype: lack of association with tumour characteristics and sur(...TRUNCATED) | "<sec><title>Background:</title><p>Glutathione S-transferase (GST)M1, a member of the μ clas(...TRUNCATED) | "<contrib id=\"A1\" contrib-type=\"author\"><name><surname>Lizard-Nacol</surname><given-names>Sarab<(...TRUNCATED) | Breast Cancer Research | "<sec><title>Introduction</title><p>The human glutathione S-transferases (GSTs) are a multigene, iso(...TRUNCATED) |
"Cyclin D<sub>1</sub> expression during rat mammary tumor development\n\t\t and its potential role (...TRUNCATED) | "<sec><title>Background:</title><p>Resistance to mammary tumorigenesis in Copenhagen rats is\n\t\t\t(...TRUNCATED) | "<contrib id=\"A1\" contrib-type=\"author\"><name><surname>Korkola</surname><given-names>James E</gi(...TRUNCATED) | Breast Cancer Research | "<sec><title>Introduction</title><p>Most strains of rats develop multiple mammary tumors when initia(...TRUNCATED) |
"Increased cell survival by inhibition of BRCA1 using an antisense approach in an estrogen responsiv(...TRUNCATED) | "\n <sec>\n <title>Introduction:</title>\n <p>Germline mutations in the bre(...TRUNCATED) | "\n <contrib id=\"A1\" contrib-type=\"author\">\n <name>\n <surname>Annab(...TRUNCATED) | Breast Cancer Research | "\n <sec>\n <title>Introduction</title>\n <p>Germline mutations in the breast and ovari(...TRUNCATED) |
A novel cell culture model for studying differentiation and apoptosis in the mouse mammary gland | "<sec><title>Background:</title><p>This paper describes the derivation and characterization of a nov(...TRUNCATED) | "<contrib id=\"A1\" contrib-type=\"author\"><name><surname>Gordon</surname><given-names>Katrina E</g(...TRUNCATED) | Breast Cancer Research | "<sec><title>Introduction</title><p>With each successive pregnancy, the mammary gland completes a cy(...TRUNCATED) |
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