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# Introduction Since the early days of MRI, a constant drive to higher main magnetic field strengths (B<sub>0</sub>) has existed. While the increase in B<sub>0</sub> leads to a superlinear increase in SNR at higher magnetic fields, the wavelengths of the electromagnetic fields at the corresponding Larmor frequencies d...
# Introduction Inflammatory bowel diseases (IBD), which include ulcerative colitis (UC), are characterised by uncontrolled intestinal inflammation. Colorectal cancer (CRC) is a life-threatening complication of UC, and UC patients are estimated to be at a 2.4 fold increased risk of CRC relative to the general populatio...
# Introduction Chikungunya virus (CHIKV) is an enveloped positive-strand RNA virus belonging to genus *Alphavirus* of the family *Togaviridae*. It is an epidemic viral disease responsible for significant global public health problem mainly in Asian and African continents. Efforts are underway in developing prevention ...
# Introduction In 1990, the Commission for Health Research and Development (COHRED) reported that less than 10% of global health research funding was spent on health conditions that account for 90% of the global disease burden. This led to an outcry that if it remained the status quo, global inequities in health will ...
# Introduction In the past two decades, *Staphylococcus aureus* has emerged one of the most important pathogens causing infections with indwelling medical devices, such as prosthetic joints, prosthetic heart valves, intravascular catheters, and cerebrospinal fluid shunts, which creates an increasing health care proble...
# Introduction The discovery of the process of transformation was key to the development of the field of molecular genetics. The first evidence that genetic information could be introduced into a cell came in 1928 when Frederick Griffith discovered that a “transforming factor” could make a harmless strain of *Streptoc...
# Introduction *Coxiella burnetii* is the Gram negative bacteria that causes the multifaceted human disease Q fever, an ever-present global public health threat. Endemic and hyperendemic regions experience regular cases of Q fever. Sporadic outbreaks also transpire, the largest being in The Netherlands between 2007 an...
# Introduction Persons with severe mental illness (SMI) including schizophrenia, bipolar disorder and major depression are approximately twice as likely to have a stroke. Increased stroke risk among those with SMI has been attributed to unhealthy lifestyle choices like tobacco use, substance abuse, low physical exerci...
# Introduction Facial expressions are critical elements in nonverbal communication, which allow observers to infer the internal state of others and - in case of negative states - to be alarmed of impeding danger or be prepared for empathic behavior. The question is how specific this warning signal can be. Is the obser...
# Introduction Accurate partners or research followers are imperative in scientific research. Mining deeper author relationships in the academic network involving various significance is achievable, which can help scholars establish potential cooperative or reference relationships. The research visual field can also b...
# Introduction There is abundant evidence worldwide on lifelong human contamination from mixtures of environmental chemicals as persistent organic pollutants (POPs); yet, the vast majority of studies report each pollutant individually, with little attention to concentrations of mixtures in individual persons or social...
# Introduction T2 ribonucleases are conserved nucleases found in all branches of life. In eukaryotic cells, T2 ribonucleases affect a variety of processes including the regulation of self-incompatibility by S-RNases in plants –, modulation of host immune cell responses by viral and schistosome T2 enzymes, and neurolog...
# Introduction Since the discovery of toll-like receptors (TLRs), we have come to appreciate their crucial role in the induction of adaptive immunity against pathogens. In response to microbes, the engagement of pathogen associated molecular patterns by TLRs initiates a complex process of antigen presenting cell (APC)...