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36,475,546
D000369:Aged, 80 and over; D006801:Humans; D005260:Female; D008297:Male; D000072657:ST Elevation Myocardial Infarction; D000088642:Nonagenarians; D012189:Retrospective Studies; D017052:Hospital Mortality; D062645:Percutaneous Coronary Intervention; D006761:Hospitals
[ "D000369", "D006801", "D005260", "D008297", "D000072657", "D000088642", "D012189", "D017052", "D062645", "D006761" ]
In-hospital outcomes in nonagenarian patients undergoing primary percutaneous coronary intervention.
BACKGROUND The aim of the present analysis was to evaluate the incidence and predictors of in-hospital adverse outcomes in nonagenarian patients undergoing primary percutaneous coronary intervention (pPCI) for ST-segment elevation myocardial infarction (STEMI). METHODS Consecutive nonagenarian patients undergoing pPC...
null
false
In-hospital outcomes in nonagenarian patients undergoing primary percutaneous coronary intervention. BACKGROUND The aim of the present analysis was to evaluate the incidence and predictors of in-hospital adverse outcomes in nonagenarian patients undergoing primary percutaneous coronary intervention (pPCI) for ST-segmen...
727,717
D001157:Arterial Occlusive Diseases; D001158:Arteries; D001160:Arterioles; D001921:Brain; D006801:Humans; D008297:Male; D008875:Middle Aged; D012867:Skin; D013116:Spinal Cord; D013577:Syndrome
[ "D001157", "D001158", "D001160", "D001921", "D006801", "D008297", "D008875", "D012867", "D013116", "D013577" ]
Papulosis atrophicans maligna (Köhlmeier-Degos disease): a disseminated occlusive vasculopathy.
Malignant atrophic papulosis usually presents as pathognomonic skin lesions followed by acute abdominal pain, bowel perforation, peritonitis, and death. Rare patients who may lack gastrointestinal symptoms present with central nervous system manifestations, including headache, paresthesias, weakness, and rapid deterior...
10,075,269
true
Papulosis atrophicans maligna (Köhlmeier-Degos disease): a disseminated occlusive vasculopathy. Malignant atrophic papulosis usually presents as pathognomonic skin lesions followed by acute abdominal pain, bowel perforation, peritonitis, and death. Rare patients who may lack gastrointestinal symptoms present with centr...
33,835,396
D000319:Adrenergic beta-Antagonists; D057911:Angiotensin Receptor Antagonists; D015897:Comorbidity; D006333:Heart Failure; D006801:Humans; D000451:Mineralocorticoid Receptor Antagonists; D013318:Stroke Volume
[ "D000319", "D057911", "D015897", "D006333", "D006801", "D000451", "D013318" ]
Update on the Impact of Comorbidities on the Efficacy and Safety of Heart Failure Medications.
Multiple newer medications benefit patients with heart failure with reduced ejection fraction (HFrEF). While these therapies benefit the broad population with HFrEF, the efficacy and safety of these therapies have been less well characterized in patients with significant comorbidities. Common comorbidities of high i...
null
false
Update on the Impact of Comorbidities on the Efficacy and Safety of Heart Failure Medications. Multiple newer medications benefit patients with heart failure with reduced ejection fraction (HFrEF). While these therapies benefit the broad population with HFrEF, the efficacy and safety of these therapies have been less w...
3,425,367
D000328:Adult; D000368:Aged; D000428:Alcohol Drinking; D004243:Divorce; D005260:Female; D006801:Humans; D006814:Hungary; D006973:Hypertension; D008297:Male; D008875:Middle Aged; D009497:Neurotic Disorders; D012307:Risk Factors; D013405:Suicide; D013406:Suicide, Attempted
[ "D000328", "D000368", "D000428", "D004243", "D005260", "D006801", "D006814", "D006973", "D008297", "D008875", "D009497", "D012307", "D013405", "D013406" ]
Neurotics at risk and suicidal behaviour in the Hungarian population.
On the basis of a study of 5,871 persons representative of the Hungarian population over the age of 20 by age, sex, place of residence and occupation, an analysis was made of the relationships between neurosis risk, suicidal behaviour, drinking habits and social and lifestyle characteristics. Measured by the Juhász Neu...
3,817,374
true
Neurotics at risk and suicidal behaviour in the Hungarian population. On the basis of a study of 5,871 persons representative of the Hungarian population over the age of 20 by age, sex, place of residence and occupation, an analysis was made of the relationships between neurosis risk, suicidal behaviour, drinking habit...
29,897,569
D015502:Absorptiometry, Photon; D001012:Aorta, Abdominal; D005260:Female; D006801:Humans; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction; D009426:Netherlands; D016016:Proportional Hazards Models; D012189:Retrospective Studies; D012307:Risk Factors; D020521:Stroke; D0660...
[ "D015502", "D001012", "D005260", "D006801", "D016030", "D008297", "D008875", "D009203", "D009426", "D016016", "D012189", "D012307", "D020521", "D066027", "D061205" ]
A high abdominal aortic calcification score by dual X-ray absorptiometry is associated with cardiovascular events after kidney transplantation.
Aortic calcification is associated with an increased risk for cardiovascular events in renal transplant recipients. This study focused on the association of abdominal aortic calcification (AAC) and cardiovascular events assessed using a dual-energy X-ray absorptiometry (DXA) scoring methodology for AAC. From 2008 to...
null
false
A high abdominal aortic calcification score by dual X-ray absorptiometry is associated with cardiovascular events after kidney transplantation. Aortic calcification is associated with an increased risk for cardiovascular events in renal transplant recipients. This study focused on the association of abdominal aortic ca...
7,354,369
D000377:Agnosia; D001933:Brain Stem; D002544:Cerebral Infarction; D006225:Hand; D006801:Humans; D008526:Medulla Oblongata; D009133:Muscular Atrophy; D011149:Pons; D013577:Syndrome; D014110:Touch; D014715:Vertebrobasilar Insufficiency
[ "D000377", "D001933", "D002544", "D006225", "D006801", "D008526", "D009133", "D011149", "D013577", "D014110", "D014715" ]
Studies on asterognosis and amyotrophy of the hand in brainstem syndromes. Relation to the symptomatology of tumours at the spinocranial junction.
Fifteen patients with symptoms of an ischaemic lesion in the vertebrobasilar territory were investigated with respect to the presence of asterognosis and amyotrophy of the hand muscles. Stereognostic disturbances were noted in 4 patients with a medullary lesion and in two patients with brainstem syndromes of less defin...
10,317,108
true
Studies on asterognosis and amyotrophy of the hand in brainstem syndromes. Relation to the symptomatology of tumours at the spinocranial junction. Fifteen patients with symptoms of an ischaemic lesion in the vertebrobasilar territory were investigated with respect to the presence of asterognosis and amyotrophy of the h...
30,516,639
D001921:Brain; D019468:Disease Management; D006801:Humans; D033162:Incidental Findings; D002532:Intracranial Aneurysm; D008279:Magnetic Resonance Imaging; D011788:Quality of Life; D012307:Risk Factors
[ "D001921", "D019468", "D006801", "D033162", "D002532", "D008279", "D011788", "D012307" ]
Management of patients with unruptured intracranial aneurysms.
Intracranial aneurysms are frequent incidental findings on cranial imaging. The decision for preventive treatment depends on the presumed risk of rupture, the efficacy and risk of complications of preventive treatment, and the quality of life having to live with an unruptured aneurysms. Data on all these factors are st...
null
false
Management of patients with unruptured intracranial aneurysms. Intracranial aneurysms are frequent incidental findings on cranial imaging. The decision for preventive treatment depends on the presumed risk of rupture, the efficacy and risk of complications of preventive treatment, and the quality of life having to live...
28,411,357
D000328:Adult; D000783:Aneurysm; D001926:Brain Death; D003928:Diabetic Nephropathies; D046148:Donor Selection; D005260:Female; D006801:Humans; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D009392:Nephrectomy; D012077:Renal Artery; D014019:Tissue Donors; D016896:Treatment Outcome; D014656:Vascular ...
[ "D000328", "D000783", "D001926", "D003928", "D046148", "D005260", "D006801", "D016030", "D008297", "D008875", "D009392", "D012077", "D014019", "D016896", "D014656" ]
Kidney Transplant From a Deceased Donor With Renal Artery Aneurysm: A Case Report.
The use of marginal kidneys or kidneys with pathologic problems (such as renal artery aneurysms in a living or deceased donor) is on the rise due to organ shortages and improvements in surgical techniques. When renal vascular abnormalities are detected during a transplant, it puts the surgeon in a difficult position to...
1,414,558
true
Kidney Transplant From a Deceased Donor With Renal Artery Aneurysm: A Case Report. The use of marginal kidneys or kidneys with pathologic problems (such as renal artery aneurysms in a living or deceased donor) is on the rise due to organ shortages and improvements in surgical techniques. When renal vascular abnormaliti...
27,852,274
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001938:Brazil; D004522:Educational Status; D005260:Female; D005783:Gender Identity; D054624:Health Status Disparities; D006801:Humans; D006973:Hypertension; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D044469:Racial Groups; D01...
[ "D000293", "D000328", "D000368", "D000369", "D001938", "D004522", "D005260", "D005783", "D054624", "D006801", "D006973", "D016015", "D008297", "D008875", "D044469", "D012737", "D012959", "D055815" ]
Educational inequalities in hypertension: complex patterns in intersections with gender and race in Brazil.
Hypertension is a major public health issue worldwide, but knowledge is scarce about its patterns and its relationship to multiple axes of social disadvantages in Latin American countries. This study describes the educational inequality in the prevalence of hypertension in Brazil, including a joint stratification by ge...
null
false
Educational inequalities in hypertension: complex patterns in intersections with gender and race in Brazil. Hypertension is a major public health issue worldwide, but knowledge is scarce about its patterns and its relationship to multiple axes of social disadvantages in Latin American countries. This study describes th...
9,431,629
D000368:Aged; D006801:Humans; D007383:Intermittent Claudication; D016015:Logistic Models; D008159:Lumbar Vertebrae; D008875:Middle Aged; D011446:Prospective Studies; D011859:Radiography; D013117:Spinal Cord Compression; D013130:Spinal Stenosis
[ "D000368", "D006801", "D007383", "D016015", "D008159", "D008875", "D011446", "D011859", "D013117", "D013130" ]
A prospective and consecutive study of surgically treated lumbar spinal stenosis. Part I: Clinical features related to radiographic findings.
METHODS A prospective study of consecutive patients undergoing surgery for central lumbar spinal stenosis. OBJECTIVE To evaluate symptoms and signs in patients undergoing surgery for central spinal stenosis and to correlate the findings to age, preoperative duration of symptoms, and radiographically detected constric...
null
false
A prospective and consecutive study of surgically treated lumbar spinal stenosis. Part I: Clinical features related to radiographic findings. METHODS A prospective study of consecutive patients undergoing surgery for central lumbar spinal stenosis. OBJECTIVE To evaluate symptoms and signs in patients undergoing surge...
552,727
D000818:Animals; D002417:Cattle; D002418:Cattle Diseases; D004322:Drainage; D005260:Female; D010493:Pericarditis; D010496:Pericardium; D013492:Suppuration
[ "D000818", "D002417", "D002418", "D004322", "D005260", "D010493", "D010496", "D013492" ]
Suppurative pericarditis treated by pericardiotomy in a cow.
The successful treatment of a single case of traumatic reticulopericarditis is described. Under general anaesthesia the pericardial sac was approached by resection of the distal part of the fifth rib and allowed to drain directly to the exterior. The discussion reviews the surgical technique.
8,748,395
true
Suppurative pericarditis treated by pericardiotomy in a cow. The successful treatment of a single case of traumatic reticulopericarditis is described. Under general anaesthesia the pericardial sac was approached by resection of the distal part of the fifth rib and allowed to drain directly to the exterior. The discussi...
18,507,271
D000328:Adult; D001741:Black or African American; D000368:Aged; D000369:Aged, 80 and over; D001794:Blood Pressure; D003071:Cognition; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D006973:Hypertension; D007407:Interviews as Topic; D008297:Male; D008568:Memory; D008875:Middle Aged; D009657:North Carol...
[ "D000328", "D001741", "D000368", "D000369", "D001794", "D003071", "D003430", "D005260", "D006801", "D006973", "D007407", "D008297", "D008568", "D008875", "D009657", "D011581", "D012044" ]
Blood pressure and memory in older African Americans.
The rates of high blood pressure among African Americans, as a group, are the highest in the world. The implications for higher average blood pressure include complications for many major chronic conditions, such as cardiovascular disease and diabetes. Less well studied is the effect of blood pressure on the cognitive ...
96,763
true
Blood pressure and memory in older African Americans. The rates of high blood pressure among African Americans, as a group, are the highest in the world. The implications for higher average blood pressure include complications for many major chronic conditions, such as cardiovascular disease and diabetes. Less well stu...
9,362,266
D000818:Animals; D066298:In Vitro Techniques; D008297:Male; D009203:Myocardial Infarction; D017202:Myocardial Ischemia; D009206:Myocardium; D051381:Rats; D017208:Rats, Wistar; D013654:Taurine; D015091:beta-Alanine
[ "D000818", "D066298", "D008297", "D009203", "D017202", "D009206", "D051381", "D017208", "D013654", "D015091" ]
Taurine depletion, a novel mechanism for cardioprotection from regional ischemia.
Three processes that have been implicated in ischemic injury are impaired Ca2+ movement, altered osmoregulation, and membrane remodeling. Because the amino acid, taurine, affects all three processes, it seemed logical that changes in the myocardial content of taurine might affect ischemic injury. To test this hypothesi...
8,058,468
true
Taurine depletion, a novel mechanism for cardioprotection from regional ischemia. Three processes that have been implicated in ischemic injury are impaired Ca2+ movement, altered osmoregulation, and membrane remodeling. Because the amino acid, taurine, affects all three processes, it seemed logical that changes in the ...
10,203,398
D001049:Apnea; D001530:Belgium; D016009:Chi-Square Distribution; D003142:Communication; D004632:Emergency Medical Services; D004634:Emergency Medical Technicians; D006323:Heart Arrest; D006801:Humans; D008020:Life Support Care; D011446:Prospective Studies; D015996:Survival Rate; D013997:Time Factors
[ "D001049", "D001530", "D016009", "D003142", "D004632", "D004634", "D006323", "D006801", "D008020", "D011446", "D015996", "D013997" ]
Do victims of an out-of-hospital cardiac arrest benefit from a training program for emergency medical dispatchers?
In this paper, we assessed the effects of a training course for emergency medical dispatchers on the handling of out-of-hospital cardiac arrest cases in the dispatch center of a two-tiered emergency medical services system. A total of 112 cardiac arrest cases were studied; 64 before and 48 after the training course. Be...
10,901,718
true
Do victims of an out-of-hospital cardiac arrest benefit from a training program for emergency medical dispatchers? In this paper, we assessed the effects of a training course for emergency medical dispatchers on the handling of out-of-hospital cardiac arrest cases in the dispatch center of a two-tiered emergency medica...
26,976,877
D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D006328:Cardiac Catheterization; D000077144:Clopidogrel; D017023:Coronary Angiography; D003324:Coronary Artery Disease; D005260:Female; D006801:Humans; D008297:Male; D006278:Medicare; D009203:Myocardial Infarction; D009204:Myocardial Revascularization; D0103...
[ "D000367", "D000368", "D000369", "D006328", "D000077144", "D017023", "D003324", "D005260", "D006801", "D008297", "D006278", "D009203", "D009204", "D010351", "D010975", "D058921", "D012017", "D012042", "D012307", "D013988", "D013997", "D016896", "D014481" ]
Outcomes According to Cardiac Catheterization Referral and Clopidogrel Use Among Medicare Patients With Non-ST-Segment Elevation Myocardial Infarction Discharged Without In-hospital Revascularization.
BACKGROUND While use of P2Y12 receptor inhibitor is recommended by guidelines, few studies have examined its effectiveness among older non-ST-segment elevation myocardial infarction patients who did not undergo coronary revascularization. RESULTS We included unrevascularized non-ST-segment elevation myocardial infarc...
null
false
Outcomes According to Cardiac Catheterization Referral and Clopidogrel Use Among Medicare Patients With Non-ST-Segment Elevation Myocardial Infarction Discharged Without In-hospital Revascularization. BACKGROUND While use of P2Y12 receptor inhibitor is recommended by guidelines, few studies have examined its effectiven...
21,558,772
D016009:Chi-Square Distribution; D002648:Child; D002675:Child, Preschool; D002710:Chlorhexidine; D003428:Cross Infection; D004311:Double-Blind Method; D005260:Female; D006330:Heart Defects, Congenital; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D015278:Intensive Care Units, Pediatric; D...
[ "D016009", "D002648", "D002675", "D002710", "D003428", "D004311", "D005260", "D006330", "D006801", "D015994", "D007223", "D007231", "D015278", "D007902", "D016015", "D008297", "D009067", "D009910", "D018410", "D053717", "D012121", "D018709", "D013997" ]
Effect of oral hygiene with 0.12% chlorhexidine gluconate on the incidence of nosocomial pneumonia in children undergoing cardiac surgery.
OBJECTIVE To evaluate the effect of oral hygiene with 0.12% chlorhexidine gluconate on the incidence of nosocomial pneumonia and ventilator-associated pneumonia (VAP) in children undergoing cardiac surgery. METHODS Prospective, randomized, double-blind, placebo-controlled trial. METHODS Pediatric intensive care uni...
null
false
Effect of oral hygiene with 0.12% chlorhexidine gluconate on the incidence of nosocomial pneumonia in children undergoing cardiac surgery. OBJECTIVE To evaluate the effect of oral hygiene with 0.12% chlorhexidine gluconate on the incidence of nosocomial pneumonia and ventilator-associated pneumonia (VAP) in children un...
15,256,222
D000818:Animals; D000975:Antioxidants; D001204:Ascorbate Oxidase; D001205:Ascorbic Acid; D001921:Brain; D002851:Chromatography, High Pressure Liquid; D003683:Dehydroascorbic Acid; D005609:Free Radicals; D005978:Glutathione; D006605:Hibernation; D010084:Oxidation-Reduction; D010100:Oxygen; D015427:Reperfusion Injury; D0...
[ "D000818", "D000975", "D001204", "D001205", "D001921", "D002851", "D003683", "D005609", "D005978", "D006605", "D010084", "D010100", "D015427", "D012589", "D013696", "D013997", "D014018", "D014527" ]
Ascorbate distribution during hibernation is independent of ascorbate redox state.
Distribution of ascorbate into tissues is an essential process in ascorbate antioxidant defense. Hibernating animals are studied as a model of tolerance to ischemia-reperfusion because of their tolerance to fluctuations in blood flow associated with prolonged torpor and periodic arousal episodes. Throughout hibernation...
6,155,104
true
Ascorbate distribution during hibernation is independent of ascorbate redox state. Distribution of ascorbate into tissues is an essential process in ascorbate antioxidant defense. Hibernating animals are studied as a model of tolerance to ischemia-reperfusion because of their tolerance to fluctuations in blood flow ass...
25,306,428
D000293:Adolescent; D000328:Adult; D000368:Aged; D001145:Arrhythmias, Cardiac; D053840:Brugada Syndrome; D000075224:Cardiac Conduction System Disease; D016757:Death, Sudden, Cardiac; D004562:Electrocardiography; D005260:Female; D005500:Follow-Up Studies; D006329:Heart Conduction System; D006801:Humans; D008297:Male; D0...
[ "D000293", "D000328", "D000368", "D001145", "D053840", "D000075224", "D016757", "D004562", "D005260", "D005500", "D006329", "D006801", "D008297", "D008875", "D015995", "D011379", "D015203", "D012189", "D015996", "D014481", "D055815" ]
Prognostic value of automatically detected early repolarization.
Early repolarization associated with sudden cardiac death is based on the presence of >1-mm J-point elevations in inferior and/or lateral leads with horizontal and/or downsloping ST segments. Automated electrocardiographic readings of early repolarization (AER) obtained in clinical practice, in contrast, are defined by...
13,353,812
true
Prognostic value of automatically detected early repolarization. Early repolarization associated with sudden cardiac death is based on the presence of >1-mm J-point elevations in inferior and/or lateral leads with horizontal and/or downsloping ST segments. Automated electrocardiographic readings of early repolarization...
12,670,851
D003951:Diagnostic Errors; D004636:Emergency Service, Hospital; D006801:Humans; D008297:Male; D008505:Medical Staff, Hospital; D008875:Middle Aged; D009203:Myocardial Infarction; D016584:Panic Disorder; D010346:Patient Care Management; D010360:Patient Transfer; D011787:Quality of Health Care; D012017:Referral and Consu...
[ "D003951", "D004636", "D006801", "D008297", "D008505", "D008875", "D009203", "D016584", "D010346", "D010360", "D011787", "D012017", "D012449" ]
Profiles in patient safety: emergency care transitions.
A 59-year-old man presented to the emergency department (ED) with the chief complaint of "panic attacks." In total, he was evaluated by 14 faculty physicians, 2 fellows, and 16 residents from emergency medicine, cardiology, neurology, psychiatry, and internal medicine. These multiple transitions were responsible, in pa...
9,367,473
true
Profiles in patient safety: emergency care transitions. A 59-year-old man presented to the emergency department (ED) with the chief complaint of "panic attacks." In total, he was evaluated by 14 faculty physicians, 2 fellows, and 16 residents from emergency medicine, cardiology, neurology, psychiatry, and internal medi...
15,559,220
D000367:Age Factors; D000368:Aged; D000596:Amino Acids; D002545:Brain Ischemia; D004305:Dose-Response Relationship, Drug; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D018697:Nootropic Agents; D017410:Practice Guidelines as Topic; D011379:Prognosis; D012307:Risk Factors; D013349:Subclavian Steal Synd...
[ "D000367", "D000368", "D000596", "D002545", "D004305", "D005500", "D006801", "D008875", "D018697", "D017410", "D011379", "D012307", "D013349", "D016896" ]
[Clinical and pathogenetical peculiarities and treatment policy in ischemic stroke of elderly and old age].
The data on randomized study of 2 groups of patients with ischemic brain hemisphere stroke of elderly and old (over 70 years) as well as middle (under 60 years) age are presented. In elderly and old age, stroke develops on the basis of common affection of major vessels, with a great role of the "steal syndrome" in its ...
null
false
[Clinical and pathogenetical peculiarities and treatment policy in ischemic stroke of elderly and old age]. The data on randomized study of 2 groups of patients with ischemic brain hemisphere stroke of elderly and old (over 70 years) as well as middle (under 60 years) age are presented. In elderly and old age, stroke d...
30,464,137
D000368:Aged; D001783:Blood Flow Velocity; D006328:Cardiac Catheterization; D004452:Echocardiography; D015150:Echocardiography, Doppler; D005260:Female; D006352:Heart Ventricles; D006439:Hemodynamics; D006801:Humans; D006976:Hypertension, Pulmonary; D008297:Male; D008875:Middle Aged; D020097:Natriuretic Peptide, Brain;...
[ "D000368", "D001783", "D006328", "D004452", "D015150", "D005260", "D006352", "D006439", "D006801", "D006976", "D008297", "D008875", "D020097", "D014655", "D016278" ]
Analysis of Biphasic Right Ventricular Outflow Doppler Waveform in Patients with Pulmonary Hypertension.
Pulmonary hypertension (PH) with pulmonary vascular disease (PVD) is a progressive and debilitating disease associated with increased pulmonary vascular resistance (PVR). Biphasic right ventricular outflow tract (RVOT) Doppler flow is frequently seen in severe PH patients with PVD. In association with hemodynamics, the...
null
false
Analysis of Biphasic Right Ventricular Outflow Doppler Waveform in Patients with Pulmonary Hypertension. Pulmonary hypertension (PH) with pulmonary vascular disease (PVD) is a progressive and debilitating disease associated with increased pulmonary vascular resistance (PVR). Biphasic right ventricular outflow tract (RV...
16,275,434
D000368:Aged; D000369:Aged, 80 and over; D019917:Blood Vessel Prosthesis Implantation; D002343:Carotid Artery, Internal; D016893:Carotid Stenosis; D002560:Cerebrovascular Circulation; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D020766:Intracranial Embolism; D008279:Magnetic Resonance ...
[ "D000368", "D000369", "D019917", "D002343", "D016893", "D002560", "D005260", "D005500", "D006801", "D015994", "D020766", "D008279", "D008297", "D008875", "D011183", "D011446", "D011474", "D011475", "D012307", "D015607" ]
Cerebral microembolization after protected carotid artery stenting in surgical high-risk patients: results of a 2-year prospective study.
BACKGROUND This was a prospective single-center study to assess and analyze cerebral embolization resulting from carotid artery stenting with neuroprotective filter devices in patients considered as poor surgical candidates for surgical carotid endarterectomy. METHODS Fifty-three consecutive patients with an internal...
null
false
Cerebral microembolization after protected carotid artery stenting in surgical high-risk patients: results of a 2-year prospective study. BACKGROUND This was a prospective single-center study to assess and analyze cerebral embolization resulting from carotid artery stenting with neuroprotective filter devices in patien...
20,846,597
D015415:Biomarkers; D001706:Biopsy; D009202:Cardiomyopathies; D019091:Critical Pathways; D004452:Echocardiography; D006801:Humans; D007501:Iron; D019190:Iron Overload; D008279:Magnetic Resonance Imaging; D009206:Myocardium; D014057:Tomography, X-Ray Computed
[ "D015415", "D001706", "D009202", "D019091", "D004452", "D006801", "D007501", "D019190", "D008279", "D009206", "D014057" ]
Iron overload cardiomyopathy: better understanding of an increasing disorder.
The prevalence of iron overload cardiomyopathy (IOC) is increasing. The spectrum of symptoms of IOC is varied. Early in the disease process, patients may be asymptomatic, whereas severely overloaded patients can have terminal heart failure complaints that are refractory to treatment. It has been shown that early recogn...
11,653,542
true
Iron overload cardiomyopathy: better understanding of an increasing disorder. The prevalence of iron overload cardiomyopathy (IOC) is increasing. The spectrum of symptoms of IOC is varied. Early in the disease process, patients may be asymptomatic, whereas severely overloaded patients can have terminal heart failure co...
27,697,440
D000991:Antithrombins; D000066491:Clinical Decision-Making; D000069604:Dabigatran; D065427:Factor Xa Inhibitors; D006471:Gastrointestinal Hemorrhage; D006801:Humans; D020300:Intracranial Hemorrhages; D017410:Practice Guidelines as Topic; D018570:Risk Assessment; D013923:Thromboembolism
[ "D000991", "D000066491", "D000069604", "D065427", "D006471", "D006801", "D020300", "D017410", "D018570", "D013923" ]
Re-initiation of dabigatran and direct factor Xa antagonists after a major bleed.
Direct oral anticoagulants (DOACs) are a relatively recent addition to the oral anticoagulant armamentarium, and provide an alternative to the use of vitamin K antagonists such as warfarin. Regardless of the type of agent used, bleeding is the major complication of anticoagulant therapy. The decision to restart oral an...
8,080,679
true
Re-initiation of dabigatran and direct factor Xa antagonists after a major bleed. Direct oral anticoagulants (DOACs) are a relatively recent addition to the oral anticoagulant armamentarium, and provide an alternative to the use of vitamin K antagonists such as warfarin. Regardless of the type of agent used, bleeding i...
27,697,440
D000991:Antithrombins; D000066491:Clinical Decision-Making; D000069604:Dabigatran; D065427:Factor Xa Inhibitors; D006471:Gastrointestinal Hemorrhage; D006801:Humans; D020300:Intracranial Hemorrhages; D017410:Practice Guidelines as Topic; D018570:Risk Assessment; D013923:Thromboembolism
[ "D000991", "D000066491", "D000069604", "D065427", "D006471", "D006801", "D020300", "D017410", "D018570", "D013923" ]
Re-initiation of dabigatran and direct factor Xa antagonists after a major bleed.
Direct oral anticoagulants (DOACs) are a relatively recent addition to the oral anticoagulant armamentarium, and provide an alternative to the use of vitamin K antagonists such as warfarin. Regardless of the type of agent used, bleeding is the major complication of anticoagulant therapy. The decision to restart oral an...
10,141,236
true
Re-initiation of dabigatran and direct factor Xa antagonists after a major bleed. Direct oral anticoagulants (DOACs) are a relatively recent addition to the oral anticoagulant armamentarium, and provide an alternative to the use of vitamin K antagonists such as warfarin. Regardless of the type of agent used, bleeding i...
160,516
D000368:Aged; D006332:Cardiomegaly; D004935:Esophageal Diseases; D005260:Female; D006325:Heart Atria; D006801:Humans; D011189:Potassium Chloride; D014456:Ulcer
[ "D000368", "D006332", "D004935", "D005260", "D006325", "D006801", "D011189", "D014456" ]
Oesophageal ulceration due to slow-release potassium in the presence of left atrial enlargement.
Ulceration of the oesophagus was suspected clinically and confirmed radiologically in a patient with an enlarged left atrium while on treatment with slow release potassium chloride. Its discontinuation resulted in resolution of symptoms. This potentially serious complication of treatment should be considered in patient...
1,081,703
true
Oesophageal ulceration due to slow-release potassium in the presence of left atrial enlargement. Ulceration of the oesophagus was suspected clinically and confirmed radiologically in a patient with an enlarged left atrium while on treatment with slow release potassium chloride. Its discontinuation resulted in resolutio...
33,805,763
D064987:Cell- and Tissue-Based Therapy; D006333:Heart Failure; D006801:Humans; D009206:Myocardium; D032383:Myocytes, Cardiac; D023822:Tissue Engineering
[ "D064987", "D006333", "D006801", "D009206", "D032383", "D023822" ]
Cardiac Cell Therapy for Heart Repair: Should the Cells Be Left Out?
Cardiovascular disease (CVD) is still the leading cause of death worldwide. Coronary artery occlusion, or myocardial infarction (MI) causes massive loss of cardiomyocytes. The ischemia area is eventually replaced by a fibrotic scar. From the mechanical dysfunctions of the scar in electronic transduction, contraction an...
4,444,606
true
Cardiac Cell Therapy for Heart Repair: Should the Cells Be Left Out? Cardiovascular disease (CVD) is still the leading cause of death worldwide. Coronary artery occlusion, or myocardial infarction (MI) causes massive loss of cardiomyocytes. The ischemia area is eventually replaced by a fibrotic scar. From the mechanica...
24,951,664
D000368:Aged; D000369:Aged, 80 and over; D000375:Aging; D001786:Blood Glucose; D002880:Chromosomes, Human, Pair 11; D015331:Cohort Studies; D053418:Death Domain Receptor Signaling Adaptor Proteins; D003924:Diabetes Mellitus, Type 2; D005215:Fasting; D005260:Female; D005787:Gene Frequency; D014644:Genetic Variation; D05...
[ "D000368", "D000369", "D000375", "D001786", "D002880", "D015331", "D053418", "D003924", "D005215", "D005260", "D005787", "D014644", "D055106", "D023281", "D020662", "D006331", "D006801", "D007328", "D008297", "D008875", "D020641", "D017422" ]
Association of levels of fasting glucose and insulin with rare variants at the chromosome 11p11.2-MADD locus: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study.
BACKGROUND Common variation at the 11p11.2 locus, encompassing MADD, ACP2, NR1H3, MYBPC3, and SPI1, has been associated in genome-wide association studies with fasting glucose and insulin (FI). In the Cohorts for Heart and Aging Research in Genomic Epidemiology Targeted Sequencing Study, we sequenced 5 gene regions at ...
null
false
Association of levels of fasting glucose and insulin with rare variants at the chromosome 11p11.2-MADD locus: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study. BACKGROUND Common variation at the 11p11.2 locus, encompassing MADD, ACP2, NR1H3, MYBPC3, and SPI1, ha...
23,336,931
D017311:Amlodipine; D000818:Animals; D000959:Antihypertensive Agents; D000069059:Atorvastatin; D002340:Carotid Artery Diseases; D017536:Carotid Artery, Common; D018932:Chemokine CCL2; D050759:Cyclin-Dependent Kinase Inhibitor p21; D004359:Drug Therapy, Combination; D042783:Endothelial Cells; D006538:Heptanoic Acids; D0...
[ "D017311", "D000818", "D000959", "D000069059", "D002340", "D017536", "D018932", "D050759", "D004359", "D042783", "D006538", "D019161", "D008297", "D011758", "D051381", "D056564", "D016159" ]
Combination benefit of amlodipine plus atorvastatin treatment on carotid atherosclerosis in Zucker metabolic rats.
OBJECTIVE Obesity is the major risk factor for metabolic syndrome and atherosclerotic cardiocerebrovascular diseases. METHODS We studied effects of amlodipine, atorvastatin, and their combination on carotid arteriosclerotic processes in a metabolic syndrome model of Zucker fatty rats. Zucker fatty rats were treated w...
null
false
Combination benefit of amlodipine plus atorvastatin treatment on carotid atherosclerosis in Zucker metabolic rats. OBJECTIVE Obesity is the major risk factor for metabolic syndrome and atherosclerotic cardiocerebrovascular diseases. METHODS We studied effects of amlodipine, atorvastatin, and their combination on caro...
8,060,581
D000328:Adult; D001786:Blood Glucose; D004039:Diet, Sodium-Restricted; D005260:Female; D018149:Glucose Intolerance; D005951:Glucose Tolerance Test; D006801:Humans; D006973:Hypertension; D007328:Insulin; D008297:Male; D008875:Middle Aged
[ "D000328", "D001786", "D004039", "D005260", "D018149", "D005951", "D006801", "D006973", "D007328", "D008297", "D008875" ]
Dietary NaCl restriction deteriorates oral glucose tolerance in hypertensive patients with impairment of glucose tolerance.
This study investigated whether the change of glycemic response to oral glucose loading with an increase of dietary NaCl intake is different between salt-sensitive and salt-resistant groups, or whether it is related to glucose tolerance on a low NaCl diet independent of salt sensitivity. The plasma glucose and insulin ...
7,575,587
true
Dietary NaCl restriction deteriorates oral glucose tolerance in hypertensive patients with impairment of glucose tolerance. This study investigated whether the change of glycemic response to oral glucose loading with an increase of dietary NaCl intake is different between salt-sensitive and salt-resistant groups, or wh...
2,310,255
D000293:Adolescent; D004562:Electrocardiography; D015716:Electrocardiography, Ambulatory; D005260:Female; D006325:Heart Atria; D006327:Heart Block; D006346:Heart Septum; D006801:Humans; D013617:Tachycardia, Supraventricular
[ "D000293", "D004562", "D015716", "D005260", "D006325", "D006327", "D006346", "D006801", "D013617" ]
Surgical cure of automatic atrial tachycardia by partial left atrial isolation.
Partial left atrial isolation was performed in a 16-year-old girl with persistent atrial tachycardia refractory to antiarrhythmic agents for 3 years. Intraoperative atrial epicardial and endocardial mapping showed that the earliest atrial activation occurred in an area lateral to the junction of the right superior pulm...
7,445,756
true
Surgical cure of automatic atrial tachycardia by partial left atrial isolation. Partial left atrial isolation was performed in a 16-year-old girl with persistent atrial tachycardia refractory to antiarrhythmic agents for 3 years. Intraoperative atrial epicardial and endocardial mapping showed that the earliest atrial a...
22,721,898
D000293:Adolescent; D000328:Adult; D000368:Aged; D005165:Factor V; D005260:Female; D005838:Genotype; D006801:Humans; D020767:Intracranial Thrombosis; D008297:Male; D042965:Methylenetetrahydrofolate Reductase (NADPH2); D008875:Middle Aged; D011110:Polymorphism, Genetic; D020641:Polymorphism, Single Nucleotide; D011516:P...
[ "D000293", "D000328", "D000368", "D005165", "D005260", "D005838", "D006801", "D020767", "D008297", "D042965", "D008875", "D011110", "D020641", "D011516", "D012307", "D014416", "D020246", "D055815" ]
Thrombophilic polymorphisms - factor V Leiden G1691A, prothrombin G20210A and MTHFR C677T - in Tunisian patients with cerebral venous thrombosis.
Cerebral venous thrombosis (CVT) has been associated with thrombophilic defects. We performed a study to evaluate the role of three single nucleotide polymorphisms (SNP), factor V Leiden G1691A (FVL), prothrombin gene mutation G20210A (FII-G20210A) and methylenotetrahydrofolate reductase variant C677T (MTHFR-C677T), as...
13,980,158
true
Thrombophilic polymorphisms - factor V Leiden G1691A, prothrombin G20210A and MTHFR C677T - in Tunisian patients with cerebral venous thrombosis. Cerebral venous thrombosis (CVT) has been associated with thrombophilic defects. We performed a study to evaluate the role of three single nucleotide polymorphisms (SNP), fac...
37,166,820
D006801:Humans; D000068258:Bevacizumab; D012170:Retinal Vein Occlusion; D008269:Macular Edema; D020533:Angiogenesis Inhibitors; D040262:Receptors, Vascular Endothelial Growth Factor; D011993:Recombinant Fusion Proteins; D058449:Intravitreal Injections
[ "D006801", "D000068258", "D012170", "D008269", "D020533", "D040262", "D011993", "D058449" ]
Cost-Utility Comparison of Bevacizumab and Aflibercept in the Treatment of Central or Hemiretinal Vein Occlusion in the SCORE2 Trial.
Retinal vein occlusion is the second most common retinal vascular disease. Bevacizumab was demonstrated in the Study of Comparative Treatments for Retinal Vein Occlusion 2 (SCORE2) to be noninferior to aflibercept with respect to visual acuity in study participants with macular edema due to central retinal vein occlusi...
null
false
Cost-Utility Comparison of Bevacizumab and Aflibercept in the Treatment of Central or Hemiretinal Vein Occlusion in the SCORE2 Trial. Retinal vein occlusion is the second most common retinal vascular disease. Bevacizumab was demonstrated in the Study of Comparative Treatments for Retinal Vein Occlusion 2 (SCORE2) to be...
32,028,046
D000328:Adult; D016757:Death, Sudden, Cardiac; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D011159:Population Surveillance; D056910:Republic of Korea; D012189:Retrospective Studies; D018570:Risk Assessment; D012307:Risk Factors; D055815:Young Adult
[ "D000328", "D016757", "D005260", "D006801", "D015994", "D008297", "D008875", "D011159", "D056910", "D012189", "D018570", "D012307", "D055815" ]
Short stature is associated with incident sudden cardiac death in a large Asian cohort.
Few data on the association between height and the risk of sudden cardiac death (SCD) in Asian populations are available. The purpose of this study was to assess the risk of SCD as related to height both in a representative Korean population and in specific subgroups. This is a retrospective cohort study of 410,1...
null
false
Short stature is associated with incident sudden cardiac death in a large Asian cohort. Few data on the association between height and the risk of sudden cardiac death (SCD) in Asian populations are available. The purpose of this study was to assess the risk of SCD as related to height both in a representative Korea...
18,413,598
D017667:Adipocytes; D050156:Adipogenesis; D000273:Adipose Tissue; D000818:Animals; D002135:Calcium-Binding Proteins; D009202:Cardiomyopathies; D003924:Diabetes Mellitus, Type 2; D020022:Genetic Predisposition to Disease; D005934:Glucagon; D007328:Insulin; D036341:Intercellular Signaling Peptides and Proteins; D024821:M...
[ "D017667", "D050156", "D000273", "D000818", "D002135", "D009202", "D003924", "D020022", "D005934", "D007328", "D036341", "D024821", "D051379", "D008822", "D009765", "D010179", "D011401", "D012333", "D054411", "D051780", "D019076" ]
Adipogenic capacity and the susceptibility to type 2 diabetes and metabolic syndrome.
To determine whether adipocyte storage capacity influences the onset and severity of type 2 diabetes and other components of the metabolic syndrome, we made normal and db/db mice resistant to obesity by overexpressing leptin receptor-b on the aP2-Lepr-b promoter. On a 4% diet, these mice have no phenotype, but on a 60%...
2,852,628
true
Adipogenic capacity and the susceptibility to type 2 diabetes and metabolic syndrome. To determine whether adipocyte storage capacity influences the onset and severity of type 2 diabetes and other components of the metabolic syndrome, we made normal and db/db mice resistant to obesity by overexpressing leptin receptor-...
37,043,326
D006801:Humans; D000818:Animals; D051379:Mice; D004195:Disease Models, Animal; D061088:Photoacoustic Techniques; D012151:Resuscitation; D006323:Heart Arrest; D000860:Hypoxia
[ "D006801", "D000818", "D051379", "D004195", "D061088", "D012151", "D006323", "D000860" ]
Neurovascular Hypoxia Trajectories Assessed by Photoacoustic Imaging in a Murine Model of Cardiac Arrest and Resuscitation.
Cardiac arrest is a common cause of death annually mainly due to postcardiac arrest syndrome that leads to multiple organ global hypoxia and dysfunction after resuscitation. The ability to quantify vasculature changes and tissue oxygenation is crucial to adapt patient treatment in order to minimize major outcomes after...
null
false
Neurovascular Hypoxia Trajectories Assessed by Photoacoustic Imaging in a Murine Model of Cardiac Arrest and Resuscitation. Cardiac arrest is a common cause of death annually mainly due to postcardiac arrest syndrome that leads to multiple organ global hypoxia and dysfunction after resuscitation. The ability to quantif...
37,558,295
D006801:Humans; D006331:Heart Diseases; D005820:Genetic Testing; D009202:Cardiomyopathies; D001145:Arrhythmias, Cardiac; D005817:Genetic Counseling
[ "D006801", "D006331", "D005820", "D009202", "D001145", "D005817" ]
A Practical Guide to Genetic Testing in Inherited Heart Disease.
Genetic testing has increasingly been shown to provide critical information regarding the treatment and management of patients with hereditary cardiomyopathies and arrhythmias and is available for a wide variety of conditions. It can provide information regarding arrhythmia risk, lifestyle recommendations, such as exer...
null
false
A Practical Guide to Genetic Testing in Inherited Heart Disease. Genetic testing has increasingly been shown to provide critical information regarding the treatment and management of patients with hereditary cardiomyopathies and arrhythmias and is available for a wide variety of conditions. It can provide information r...
8,538,901
D017545:Aortic Aneurysm, Thoracic; D002102:Cadaver; D006801:Humans; D006965:Hyperplasia; D011093:Polyethylene Terephthalates; D019736:Prostheses and Implants; D017539:Tunica Intima
[ "D017545", "D002102", "D006801", "D006965", "D011093", "D019736", "D017539" ]
Pathological study of implanted dacron grafts in surgery of thoracic aortic aneurysms.
We studied woven dacron grafts that had been implanted in 5 patients of thoracic aortic aneurysms. In addition to usual stains, immunocytochemical analysis was performed using monoclonal antibodies to the muscle actin (HHF35) and to the macrophage (HAM56). In the graft of 5 and 24 days implantation, thin thrombi contai...
14,348,338
true
Pathological study of implanted dacron grafts in surgery of thoracic aortic aneurysms. We studied woven dacron grafts that had been implanted in 5 patients of thoracic aortic aneurysms. In addition to usual stains, immunocytochemical analysis was performed using monoclonal antibodies to the muscle actin (HHF35) and to ...
16,583,933
D001024:Aortic Valve Stenosis; D002404:Catheterization; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D016896:Treatment Outcome; D014463:Ultrasonography
[ "D001024", "D002404", "D006801", "D007223", "D007231", "D008297", "D016896", "D014463" ]
[Transluminal balloon valvuloplasty in neonates and infants with critical aortic stenosis].
The purpose of this study was to evaluate children who underwent balloon valvuloplasty due to critical aortic stenosis following clinical (low cardiac output, cardiogenic shock, congestive heart failure) and echocardiographic criteria (morphological evidence of left ventricular hypertrophy, with depression of left vent...
null
false
[Transluminal balloon valvuloplasty in neonates and infants with critical aortic stenosis]. The purpose of this study was to evaluate children who underwent balloon valvuloplasty due to critical aortic stenosis following clinical (low cardiac output, cardiogenic shock, congestive heart failure) and echocardiographic cr...
30,870,037
D000287:Administration, Topical; D017719:Diabetic Foot; D016503:Drug Delivery Systems; D000076722:Drug Development; D055808:Drug Discovery; D006801:Humans; D004364:Pharmaceutical Preparations; D014945:Wound Healing; D014947:Wounds and Injuries
[ "D000287", "D017719", "D016503", "D000076722", "D055808", "D006801", "D004364", "D014945", "D014947" ]
The discovery and development of topical medicines for wound healing.
Chronic, nonhealing skin wounds claim >3% of the health-care budget in industrialized countries, and the incidence is rising. Currently, two parallel trends influence innovations within the field of wound healing: the need to reduce spread of antibiotic resistance and the emerging use of health economy and value-based ...
null
false
The discovery and development of topical medicines for wound healing. Chronic, nonhealing skin wounds claim >3% of the health-care budget in industrialized countries, and the incidence is rising. Currently, two parallel trends influence innovations within the field of wound healing: the need to reduce spread of antibio...
2,234,326
D000818:Animals; D001769:Blood; D004195:Disease Models, Animal; D004912:Erythrocytes; D005263:Femoral Artery; D006801:Humans; D002546:Ischemic Attack, Transient; D007962:Leukocytes; D008297:Male; D010949:Plasma; D051381:Rats; D011919:Rats, Inbred Strains
[ "D000818", "D001769", "D004195", "D004912", "D005263", "D006801", "D002546", "D007962", "D008297", "D010949", "D051381", "D011919" ]
A rat femoral artery model for vasospasm.
A new animal model for vasospasm using rat femoral artery has been developed. Whole blood, washed erythrocytes, or leukocytes in platelet-rich plasma were selectively applied to the adventitial surface of the femoral artery for 7 days in 15 rats, after which the vessels were perfusion-fixed and examined by light and tr...
14,509,119
true
A rat femoral artery model for vasospasm. A new animal model for vasospasm using rat femoral artery has been developed. Whole blood, washed erythrocytes, or leukocytes in platelet-rich plasma were selectively applied to the adventitial surface of the femoral artery for 7 days in 15 rats, after which the vessels were pe...
2,755,121
D000818:Animals; D001145:Arrhythmias, Cardiac; D003243:Consciousness; D003327:Coronary Disease; D004110:Diltiazem; D004562:Electrocardiography; D006339:Heart Rate; D008297:Male; D015428:Myocardial Reperfusion Injury; D009543:Nifedipine; D051381:Rats; D011919:Rats, Inbred Strains; D013610:Tachycardia; D014693:Ventricula...
[ "D000818", "D001145", "D003243", "D003327", "D004110", "D004562", "D006339", "D008297", "D015428", "D009543", "D051381", "D011919", "D013610", "D014693", "D014700" ]
Reperfusion-induced arrhythmias in the conscious rat: a comparative study with three calcium antagonists.
The effects of three calcium antagonists (diltiazem, verapamil, and nifedipine) on reperfusion-induced arrhythmias were compared in a conscious rat preparation with coronary artery occlusion and implanted electrocardiogram limb electrodes. Upon reperfusion after a 5-min period of occlusion, all (15/15) untreated contro...
7,665,470
true
Reperfusion-induced arrhythmias in the conscious rat: a comparative study with three calcium antagonists. The effects of three calcium antagonists (diltiazem, verapamil, and nifedipine) on reperfusion-induced arrhythmias were compared in a conscious rat preparation with coronary artery occlusion and implanted electroca...
17,532,413
D000293:Adolescent; D000328:Adult; D000368:Aged; D006348:Cardiac Surgical Procedures; D004724:Endoscopy; D005260:Female; D006338:Heart Neoplasms; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D016896:Treatment Outcome
[ "D000293", "D000328", "D000368", "D006348", "D004724", "D005260", "D006338", "D006801", "D008297", "D008875", "D012189", "D016896" ]
Endoscopic cardiac tumor resection.
BACKGROUND The purpose of this study is to report our 9 years' experience with endoscopic cardiac tumor resection using the port access approach. METHODS From March 1997 to December 2005, 27 patients (mean age, 56.2 +/- 16.9 years; 70% female) underwent endoscopic cardiac tumor resection using endocardiopulmonary byp...
null
false
Endoscopic cardiac tumor resection. BACKGROUND The purpose of this study is to report our 9 years' experience with endoscopic cardiac tumor resection using the port access approach. METHODS From March 1997 to December 2005, 27 patients (mean age, 56.2 +/- 16.9 years; 70% female) underwent endoscopic cardiac tumor res...
17,578,050
D000368:Aged; D000925:Anticoagulants; D001021:Aortic Valve; D017984:Enoxaparin; D005240:Feasibility Studies; D006350:Heart Valve Prosthesis; D019918:Heart Valve Prosthesis Implantation; D006470:Hemorrhage; D006801:Humans; D019934:International Normalized Ratio; D008943:Mitral Valve; D019990:Perioperative Care; D011446:...
[ "D000368", "D000925", "D001021", "D017984", "D005240", "D006350", "D019918", "D006470", "D006801", "D019934", "D008943", "D019990", "D011446", "D012042", "D013923" ]
Periprocedural bridging therapy with low-molecular-weight heparin in chronically anticoagulated patients with prosthetic mechanical heart valves: experience in 116 patients from the prospective BRAVE registry.
OBJECTIVE The study aim was to determine the safety and feasibility of a standardized bridging regimen in patients with mechanical heart valves at high thromboembolic risk, using low-molecular-weight heparin (LMWH). METHODS Since the year 2000, all patients at the authors' institution, with mechanical heart valves an...
null
false
Periprocedural bridging therapy with low-molecular-weight heparin in chronically anticoagulated patients with prosthetic mechanical heart valves: experience in 116 patients from the prospective BRAVE registry. OBJECTIVE The study aim was to determine the safety and feasibility of a standardized bridging regimen in pati...
20,881,568
D017542:Aneurysm, Ruptured; D002543:Cerebral Hemorrhage; D002552:Cerebral Ventricles; D015331:Cohort Studies; D005260:Female; D006801:Humans; D002532:Intracranial Aneurysm; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D009422:Nervous System Diseases; D011237:Predictive Valu...
[ "D017542", "D002543", "D002552", "D015331", "D005260", "D006801", "D002532", "D016015", "D008297", "D008875", "D015999", "D009422", "D011237", "D012189", "D012720", "D016896" ]
Intraventricular hemorrhage volume predicts poor outcomes but not delayed ischemic neurological deficits among patients with ruptured cerebral aneurysms.
BACKGROUND Intraventricular hemorrhage (IVH) predicts worse outcomes following aneurysmal subarachnoid hemorrhage (SAH). One potential mechanism is that IVH predisposes to the development of delayed ischemic neurological deficits (DINDs). No previous studies have evaluated the association between IVH volume (in millili...
null
false
Intraventricular hemorrhage volume predicts poor outcomes but not delayed ischemic neurological deficits among patients with ruptured cerebral aneurysms. BACKGROUND Intraventricular hemorrhage (IVH) predicts worse outcomes following aneurysmal subarachnoid hemorrhage (SAH). One potential mechanism is that IVH predispos...
12,939,567
D003327:Coronary Disease; D006801:Humans; D006973:Hypertension; D007333:Insulin Resistance
[ "D003327", "D006801", "D006973", "D007333" ]
Insulin resistance, hypertension, and coronary heart disease.
The goals of this review are two-fold: to examine the evidence in support of a role for insulin resistance and compensatory hyperinsulinemia in the pathogenesis of essential hypertension, and to evaluate the hypothesis that insulin resistance and its manifestations play major roles in the development of coronary heart ...
6,421,089
true
Insulin resistance, hypertension, and coronary heart disease. The goals of this review are two-fold: to examine the evidence in support of a role for insulin resistance and compensatory hyperinsulinemia in the pathogenesis of essential hypertension, and to evaluate the hypothesis that insulin resistance and its manifes...
9,391,222
D000368:Aged; D002121:Calcium Channel Blockers; D002561:Cerebrovascular Disorders; D003680:Deglutition Disorders; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D009543:Nifedipine; D010865:Pilot Projects
[ "D000368", "D002121", "D002561", "D003680", "D004311", "D005260", "D006801", "D008297", "D009543", "D010865" ]
Pharmacological treatment of dysphagia in stroke.
The pharynx is important for a normal swallow and it has been suggested that pharmacological agents may play a role in the management of pharyngeal dysphagia, but none have been formally evaluated. A pilot double-blind, placebo-controlled study was undertaken in 17 hospitalized patients with persistent dysphagia 2 week...
2,903,413
true
Pharmacological treatment of dysphagia in stroke. The pharynx is important for a normal swallow and it has been suggested that pharmacological agents may play a role in the management of pharyngeal dysphagia, but none have been formally evaluated. A pilot double-blind, placebo-controlled study was undertaken in 17 hosp...
29,878,125
D000199:Actins; D000293:Adolescent; D000328:Adult; D000818:Animals; D002311:Cardiomyopathy, Dilated; D016022:Case-Control Studies; D051338:Cofilin 1; D005260:Female; D006321:Heart; D006801:Humans; D034904:Lamin Type A; D008297:Male; D051379:Mice; D008875:Middle Aged; D019950:Mitogen-Activated Protein Kinase 1; D048052:...
[ "D000199", "D000293", "D000328", "D000818", "D002311", "D016022", "D051338", "D005260", "D006321", "D006801", "D034904", "D008297", "D051379", "D008875", "D019950", "D048052", "D009154", "D010766", "D015398", "D055815" ]
Cofilin-1 phosphorylation catalyzed by ERK1/2 alters cardiac actin dynamics in dilated cardiomyopathy caused by lamin A/C gene mutation.
Hyper-activation of extracellular signal-regulated kinase (ERK) 1/2 contributes to heart dysfunction in cardiomyopathy caused by mutations in the lamin A/C gene (LMNA cardiomyopathy). The mechanism of how this affects cardiac function is unknown. We show that active phosphorylated ERK1/2 directly binds to and catalyzes...
4,535,839
true
Cofilin-1 phosphorylation catalyzed by ERK1/2 alters cardiac actin dynamics in dilated cardiomyopathy caused by lamin A/C gene mutation. Hyper-activation of extracellular signal-regulated kinase (ERK) 1/2 contributes to heart dysfunction in cardiomyopathy caused by mutations in the lamin A/C gene (LMNA cardiomyopathy)....
15,338,141
D002545:Brain Ischemia; D002986:Clinical Trials as Topic; D015897:Comorbidity; D019317:Evidence-Based Medicine; D005260:Female; D005343:Fibrinolytic Agents; D005858:Germany; D006801:Humans; D015994:Incidence; D008297:Male; D015995:Prevalence; D018570:Risk Assessment; D012307:Risk Factors; D020521:Stroke; D019851:Thromb...
[ "D002545", "D002986", "D015897", "D019317", "D005260", "D005343", "D005858", "D006801", "D015994", "D008297", "D015995", "D018570", "D012307", "D020521", "D019851" ]
[Thrombophilias in patients with ischemic stroke. Indication and calculated costs for evidence-based diagnostics and treatment].
Patients with ischemic stroke are sometimes found to have an underlying inherited (deficiency of protein C, protein S, antithrombin III, activated protein C resistance, prothrombin gene mutation, hyperhomocysteinemia) or acquired thrombophilia (lupus anticoagulant and anticardiolipin antibodies, hyperhomocysteinemia). ...
null
false
[Thrombophilias in patients with ischemic stroke. Indication and calculated costs for evidence-based diagnostics and treatment]. Patients with ischemic stroke are sometimes found to have an underlying inherited (deficiency of protein C, protein S, antithrombin III, activated protein C resistance, prothrombin gene mutat...
19,436,803
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D001021:Aortic Valve; D001022:Aortic Valve Insufficiency; D001024:Aortic Valve Stenosis; D002648:Child; D004697:Endocarditis, Bacterial; D005260:Female; D006330:Heart Defects, Congenital; D017052:Hospital Mortality; D006801:Humans; D008297:Male; D008...
[ "D000293", "D000328", "D000367", "D000368", "D001021", "D001022", "D001024", "D002648", "D004697", "D005260", "D006330", "D017052", "D006801", "D008297", "D008875", "D011379", "D016016", "D012189", "D018570", "D012307", "D014463", "D055815" ]
Impact of bicuspid aortic valve on complications and death in infective endocarditis of native aortic valves.
We retrospectively investigated the impact of bicuspid aortic valve on the prognosis of patients who had definite infective endocarditis of the native aortic valve.Of 51 patients, a bicuspid aortic valve was present in 22 (43%); the other 29 had tricuspid aortic valves. On average, the patients who had bicuspid valves ...
2,240,429
true
Impact of bicuspid aortic valve on complications and death in infective endocarditis of native aortic valves. We retrospectively investigated the impact of bicuspid aortic valve on the prognosis of patients who had definite infective endocarditis of the native aortic valve.Of 51 patients, a bicuspid aortic valve was pr...
23,443,603
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019917:Blood Vessel Prosthesis Implantation; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D005260:Female; D005343:Fibrinolytic Agents; D006083:Graft Occlusion, Vascular; D006470:Hemorrhage; D006493:Heparin; D006495:Heparin, Low-...
[ "D000328", "D000368", "D000369", "D019917", "D004305", "D004334", "D005260", "D005343", "D006083", "D006470", "D006493", "D006495", "D006801", "D035002", "D008297", "D008875", "D018579", "D058729", "D012307", "D013927", "D013997", "D016896", "D014654" ]
Risk-adjusted strategies in the prevention of early arterial thrombosis following lower extremity arterial reconstruction: a comparison of unfractionated versus low molecular weight heparin.
OBJECTIVE In vascular surgery postoperative thrombosis prophylaxis must sufficiently prevent arterial thrombosis. This cohort study examines different therapeutic approaches of unfractionated heparin (UFH) or low molecular weight heparin (LMWH) after vascular reconstruction. METHODS Four hundred seventy-five patients...
null
false
Risk-adjusted strategies in the prevention of early arterial thrombosis following lower extremity arterial reconstruction: a comparison of unfractionated versus low molecular weight heparin. OBJECTIVE In vascular surgery postoperative thrombosis prophylaxis must sufficiently prevent arterial thrombosis. This cohort stu...
20,044,737
D030541:Databases, Genetic; D005260:Female; D056726:Genetic Association Studies; D020022:Genetic Predisposition to Disease; D006801:Humans; D006973:Hypertension; D008297:Male; D011941:Receptors, Adrenergic
[ "D030541", "D005260", "D056726", "D020022", "D006801", "D006973", "D008297", "D011941" ]
Synopsis and data synthesis of genetic association studies in hypertension for the adrenergic receptor family genes: the CUMAGAS-HYPERT database.
BACKGROUND The adrenergic receptor (adrenoceptor) family genes have been extensively studied as candidate genes in hypertension but the results of individual genetic association studies (GAS) are controversial and inconclusive. To clarify these data, a systematic assessment of GAS for adrenoceptor family genes in hyper...
null
false
Synopsis and data synthesis of genetic association studies in hypertension for the adrenergic receptor family genes: the CUMAGAS-HYPERT database. BACKGROUND The adrenergic receptor (adrenoceptor) family genes have been extensively studied as candidate genes in hypertension but the results of individual genetic associat...
30,797,031
D000368:Aged; D000784:Aortic Dissection; D001013:Aorta, Thoracic; D017545:Aortic Aneurysm, Thoracic; D019917:Blood Vessel Prosthesis Implantation; D002140:California; D057510:Endovascular Procedures; D006764:Hospitals, Community; D016304:Hospitals, Private; D006801:Humans; D061214:Patient Safety; D011183:Postoperative ...
[ "D000368", "D000784", "D001013", "D017545", "D019917", "D002140", "D057510", "D006764", "D016304", "D006801", "D061214", "D011183", "D018570", "D012307", "D013997", "D016896" ]
Hybrid Aortic Arch Debranching and TEVAR Is Safe in a Private, Community Hospital.
BACKGROUND Hybrid open cervical vessel debranching and thoracic endovascular aortic repair (TEVAR) is a treatment option in the management of aortic arch or proximal descending thoracic aortic aneurysms. However, these patients are often referred to tertiary care academic centers for aneurysm repair. Our study looks to...
null
false
Hybrid Aortic Arch Debranching and TEVAR Is Safe in a Private, Community Hospital. BACKGROUND Hybrid open cervical vessel debranching and thoracic endovascular aortic repair (TEVAR) is a treatment option in the management of aortic arch or proximal descending thoracic aortic aneurysms. However, these patients are often...
16,639,688
D000368:Aged; D001243:Assisted Circulation; D002294:Carcinoma, Squamous Cell; D003131:Combined Modality Therapy; D015199:Extracorporeal Membrane Oxygenation; D006801:Humans; D007423:Intra-Aortic Balloon Pumping; D008175:Lung Neoplasms; D008297:Male; D011013:Pneumonectomy; D019106:Postoperative Hemorrhage; D011651:Pulmo...
[ "D000368", "D001243", "D002294", "D003131", "D015199", "D006801", "D007423", "D008175", "D008297", "D011013", "D019106", "D011651", "D012770", "D012771" ]
Mechanical circulatory support for profound cardiac circulatory shock status due to postoperative pulmonary artery bleeding.
A 77-year-old patient suffering from life-threatening pulmonary artery bleeding after pulmonary lobectomy was resuscitated but had refractory cardiogenic shock after the bleeding was controlled. We used mechanical circulatory support with extracorporeal membrane oxygenation and intra-aortic balloon pump to overcome the...
11,887,378
true
Mechanical circulatory support for profound cardiac circulatory shock status due to postoperative pulmonary artery bleeding. A 77-year-old patient suffering from life-threatening pulmonary artery bleeding after pulmonary lobectomy was resuscitated but had refractory cardiogenic shock after the bleeding was controlled. ...
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PubMed Cardiovascular Subset Dataset

This dataset is a curated subset of PubMed articles filtered to include those related to Cardiovascular Disease and its associated subcategories ("children"). It is designed to support research and analysis in cardiovascular health, epidemiology, and related biomedical fields by providing structured metadata along with the article text.

Dataset Overview

  • Source: Derived from PubMed, the dataset includes articles indexed with relevance to cardiovascular conditions.
  • Scope: Focused on cardiovascular disease, including its broader categories and subtypes, ensuring that users can perform detailed analyses on relevant biomedical literature.
  • Curation: Articles were selected using MeSH term filtering, where both the primary term for Cardiovascular Disease and its children terms were used to narrow the selection.

Dataset Structure

The dataset is structured with the following columns:

  • pmid:
    A unique PubMed Identifier for each article. This numeric code allows easy cross-referencing with the full PubMed record.

  • mesh_terms:
    A string containing Medical Subject Headings (MeSH) terms with their corresponding codes (e.g., "D000369:Aged, 80 and over"). These terms classify the content and facilitate detailed filtering based on biomedical topics.

  • mesh_terms_ui_list:
    A list of MeSH term unique identifiers extracted from the mesh_terms field. This format aids in programmatic filtering and analysis by isolating the identifier codes.

  • title:
    The title of the research article. It offers a brief overview of the study focus, allowing users to quickly gauge the article's relevance.

  • abstract:
    A summary of the article, including background, methods, results, and conclusions. This field provides a concise yet informative snapshot of the research content.

  • index:
    Position in pubmed_en. In case of not being contained, it is null.

  • in_total_pubmed:
    A boolean indicator that shows whether the article is part of the broader PubMed_en dataset.

  • text:
    A consolidated field combining key elements (often the title and abstract) into one text block.

Example Record

{
  "pmid": 36475546,
  "mesh_terms": "D000369:Aged, 80 and over; D006801:Humans; D005260:Female; D008297:Male; D000072657:ST Elevation Myocardial Infarction; D000088642:Nonagenarians; D012189:Retrospective Studies; D017052:Hospital Mortality; D062645:Percutaneous Coronary Intervention; D006761:Hospitals",
  "mesh_terms_ui_list": [
    "D000369",
    "D006801",
    "D005260",
    "D008297",
    "D000072657",
    "D000088642",
    "D012189",
    "D017052",
    "D062645",
    "D006761"
  ],
  "title": "In-hospital outcomes in nonagenarian patients undergoing primary percutaneous coronary intervention.",
  "abstract": "BACKGROUND\nThe aim of the present analysis was to evaluate the incidence and predictors of in-hospital adverse outcomes in nonagenarian patients undergoing primary percutaneous coronary intervention (pPCI) for ST-segment elevation myocardial infarction (STEMI)...",
  "index": null,
  "in_total_pubmed": false,
  "text": "In-hospital outcomes in nonagenarian patients undergoing primary percutaneous coronary intervention. BACKGROUND\nThe aim of the present analysis was to evaluate the incidence and predictors of in-hospital adverse outcomes in nonagenarian patients undergoing primary percutaneous coronary intervention (pPCI) for ST-segment elevation myocardial infarction (STEMI)..."
}
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