Datasets:

DBbun
/

oligotox-phase2-dataset

modification_id,oligo_id,source_id,sugar_chemistry,backbone_class,phosphorothioate_fraction,phosphorothioate_tertile,GalNAc_conjugated,modification_pattern,modification_locations,purity,purity_source_label,characterization_method,characterization_source_label,record_origin,value_origin
MOD_CTRL_OLIGO_NEG_VEHICLE_MOCK,CTRL_OLIGO_NEG_VEHICLE_MOCK,MEMO_OLIGOTOX_PHASE2_ALIGNMENT,not_applicable,low_or_no_PS,0.0,low_PS,0,not_applicable,not_applicable,1.0,literature_grounded_generated,not_applicable,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_CTRL_OLIGO_NEG_LOW_RISK,CTRL_OLIGO_NEG_LOW_RISK,MEMO_OLIGOTOX_PHASE2_ALIGNMENT,2prime_OMe,low_or_no_PS,0.05,low_PS,0,2prime_OMe|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_1,0.985,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_CTRL_OLIGO_NEG_RAPIROSIRAN_LIKE,CTRL_OLIGO_NEG_RAPIROSIRAN_LIKE,RAPIROSIRAN_SANYAL_2025,mixed,partial_PS,0.22,low_PS,1,mixed|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_4,0.975,inferred_from_paper,LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_CTRL_OLIGO_NEG_SPHEROID_TOLERATED,CTRL_OLIGO_NEG_SPHEROID_TOLERATED,LIVER_SPHEROID_SCHOLTEN_2026,mixed,partial_PS,0.18,low_PS,1,mixed|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_4,0.972,inferred_from_paper,HPLC+LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_CTRL_OLIGO_POS_HIGH_PS_HIGH_DOSE,CTRL_OLIGO_POS_HIGH_PS_HIGH_DOSE,MEMO_OLIGOTOX_PHASE2_ALIGNMENT,2prime_MOE,high_PS,0.98,high_PS,0,2prime_MOE|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_18,0.955,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_CTRL_OLIGO_POS_HIGH_OFFTARGET,CTRL_OLIGO_POS_HIGH_OFFTARGET,MEMO_OLIGOTOX_PHASE2_ALIGNMENT,2prime_F,partial_PS,0.25,low_PS,1,2prime_F|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_5,0.965,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_CTRL_OLIGO_POS_TRANSCRIPTOMIC_STRESS,CTRL_OLIGO_POS_TRANSCRIPTOMIC_STRESS,MEMO_OLIGOTOX_PHASE2_ALIGNMENT,mixed,partial_PS,0.42,medium_PS,1,mixed|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_8,0.955,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_CTRL_OLIGO_POS_LNA_GAPMER_HIGH_RISK,CTRL_OLIGO_POS_LNA_GAPMER_HIGH_RISK,RO7239958_GERETTI_2025,LNA,high_PS,0.96,high_PS,1,LNA|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_17,0.952,inferred_from_paper,LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_CTRL_OLIGO_NEG_TARGETED_LNP_ASGPR,CTRL_OLIGO_NEG_TARGETED_LNP_ASGPR,MOHAMED_NANOPARTICLE_HEPATITIS_2026,2prime_OMe,partial_PS,0.12,low_PS,0,2prime_OMe|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_2,0.982,inferred_from_paper,HPLC+LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_CTRL_OLIGO_POS_DELIVERY_NP_STRESS,CTRL_OLIGO_POS_DELIVERY_NP_STRESS,MOHAMED_NANOPARTICLE_HEPATITIS_2026,2prime_F,partial_PS,0.3,low_PS,0,2prime_F|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_6,0.948,inferred_from_paper,LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_CTRL_OLIGO_NEG_BALANCED_HYBRID_RNA_LNP,CTRL_OLIGO_NEG_BALANCED_HYBRID_RNA_LNP,MENG_HYBRID_RNA_LNP_HCC_2025,2prime_OMe,partial_PS,0.18,low_PS,0,2prime_OMe|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_4,0.976,inferred_from_paper,HPLC+LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_CTRL_OLIGO_POS_IMMUNE_ACTIVATING_RNA_LNP_STRESS,CTRL_OLIGO_POS_IMMUNE_ACTIVATING_RNA_LNP_STRESS,MENG_HYBRID_RNA_LNP_HCC_2025,2prime_F,partial_PS,0.34,medium_PS,0,2prime_F|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_7,0.958,inferred_from_paper,LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_CTRL_OLIGO_NEG_APOB_ASO_LOW_LIPID_STRESS,CTRL_OLIGO_NEG_APOB_ASO_LOW_LIPID_STRESS,CHEN_OVARIAN_MTTP_APOB_MIPOMERSEN_2025,2prime_MOE,partial_PS,0.32,low_PS,0,2prime_MOE|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_6,0.978,inferred_from_paper,HPLC+LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_CTRL_OLIGO_POS_APOB_ASO_LIPID_EXPORT_STRESS,CTRL_OLIGO_POS_APOB_ASO_LIPID_EXPORT_STRESS,CHEN_OVARIAN_MTTP_APOB_MIPOMERSEN_2025,2prime_MOE,high_PS,0.78,high_PS,0,2prime_MOE|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_15,0.955,inferred_from_paper,LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_CTRL_OLIGO_NEG_SULT1B1_SIRNA_LIPID_RESCUE,CTRL_OLIGO_NEG_SULT1B1_SIRNA_LIPID_RESCUE,LU_SULT1B1_SE_MASLD_2026,2prime_OMe,partial_PS,0.14,low_PS,0,2prime_OMe|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_3,0.976,inferred_from_paper,HPLC+LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_CTRL_OLIGO_POS_MASLD_EPIGENETIC_LIPID_ACCUMULATION,CTRL_OLIGO_POS_MASLD_EPIGENETIC_LIPID_ACCUMULATION,LU_SULT1B1_SE_MASLD_2026,2prime_F,partial_PS,0.28,low_PS,0,2prime_F|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_6,0.956,inferred_from_paper,LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_CTRL_OLIGO_NEG_ANGPTL3_SIRNA_LIVER_SAFETY,CTRL_OLIGO_NEG_ANGPTL3_SIRNA_LIVER_SAFETY,OOSTVEEN_ANGPTL3_LIVER_SAFETY_2023,2prime_OMe,partial_PS,0.16,low_PS,1,2prime_OMe|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_3,0.978,inferred_from_paper,HPLC+LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_CTRL_OLIGO_POS_ANGPTL3_ASO_HEPATIC_FAT_ALT_SIGNAL,CTRL_OLIGO_POS_ANGPTL3_ASO_HEPATIC_FAT_ALT_SIGNAL,OOSTVEEN_ANGPTL3_LIVER_SAFETY_2023,LNA,high_PS,0.88,high_PS,1,LNA|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_17,0.955,inferred_from_paper,LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_CTRL_OLIGO_POS_PNPLA3_I148M_HOMOZYGOUS_LIPID_STRESS,CTRL_OLIGO_POS_PNPLA3_I148M_HOMOZYGOUS_LIPID_STRESS,PNPLA3_ROMEO_VALENTI_2025,mixed,partial_PS,0.24,low_PS,1,mixed|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_5,0.974,inferred_from_paper,HPLC+LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_CTRL_OLIGO_NEG_PNPLA3_SIRNA_HOMOZYGOTE_RESCUE,CTRL_OLIGO_NEG_PNPLA3_SIRNA_HOMOZYGOTE_RESCUE,PNPLA3_ROMEO_VALENTI_2025,mixed,partial_PS,0.18,low_PS,1,mixed|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_4,0.981,inferred_from_paper,HPLC+LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_CTRL_OLIGO_CONTEXT_PNPLA3_HETEROZYGOUS_UNCERTAIN_RESPONSE,CTRL_OLIGO_CONTEXT_PNPLA3_HETEROZYGOUS_UNCERTAIN_RESPONSE,PNPLA3_ROMEO_VALENTI_2025,mixed,partial_PS,0.52,medium_PS,1,mixed|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_10,0.972,inferred_from_paper,HPLC+LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_CTRL_OLIGO_NEG_CHOLESTEROL_SIRNA_MUSCLE_TOLERATED,CTRL_OLIGO_NEG_CHOLESTEROL_SIRNA_MUSCLE_TOLERATED,ENGELBEEN_ALK4_MUSCLE_SIRNA_2023,mixed,partial_PS,0.12,low_PS,0,mixed|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_2,0.978,inferred_from_paper,HPLC+LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_CTRL_OLIGO_CONTEXT_EXTRAHEPATIC_SIRNA_LIVER_EXPOSURE,CTRL_OLIGO_CONTEXT_EXTRAHEPATIC_SIRNA_LIVER_EXPOSURE,ENGELBEEN_ALK4_MUSCLE_SIRNA_2023,mixed,partial_PS,0.12,low_PS,0,mixed|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_2,0.978,inferred_from_paper,HPLC+LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_CTRL_OLIGO_NEG_PERSONALIZED_ASO_ACCEPTABLE_SAFETY,CTRL_OLIGO_NEG_PERSONALIZED_ASO_ACCEPTABLE_SAFETY,KIM_MILASEN_CUSTOM_ASO_2019,2prime_MOE,high_PS,1.0,high_PS,0,2prime_MOE|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_21,0.985,inferred_from_paper,HPLC+LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_CTRL_OLIGO_CONTEXT_CUSTOM_ASO_TOX_WORKFLOW,CTRL_OLIGO_CONTEXT_CUSTOM_ASO_TOX_WORKFLOW,KIM_MILASEN_CUSTOM_ASO_2019,2prime_MOE,high_PS,1.0,high_PS,0,2prime_MOE|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_21,0.985,inferred_from_paper,HPLC+LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_CTRL_OLIGO_NEG_GALNAC_ASO_NAFLD_TARGETED,CTRL_OLIGO_NEG_GALNAC_ASO_NAFLD_TARGETED,KEATING_ASO_OBESITY_NAFLD_2022,2prime_MOE,partial_PS,0.42,medium_PS,1,2prime_MOE|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_8,0.982,inferred_from_paper,HPLC+LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_CTRL_OLIGO_POS_HIGH_AFFINITY_GAPMER_SEQUENCE_MOTIF,CTRL_OLIGO_POS_HIGH_AFFINITY_GAPMER_SEQUENCE_MOTIF,KEATING_ASO_OBESITY_NAFLD_2022,LNA,high_PS,0.98,high_PS,0,LNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_18,0.95,inferred_from_paper,LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_CTRL_OLIGO_CONTEXT_ASO_TYPE_I_IFN_OFFTARGET,CTRL_OLIGO_CONTEXT_ASO_TYPE_I_IFN_OFFTARGET,KEATING_ASO_OBESITY_NAFLD_2022,2prime_MOE,high_PS,0.78,high_PS,0,2prime_MOE|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_14,0.97,inferred_from_paper,HPLC+LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_CTRL_OLIGO_NEG_LNA_GAPMER_SEQUENCE_REDESIGN_LOW_TOX,CTRL_OLIGO_NEG_LNA_GAPMER_SEQUENCE_REDESIGN_LOW_TOX,HAGEDORN_LNA_HEPATOTOX_RF_2013,LNA,high_PS,0.9,high_PS,0,LNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_11,0.91,inferred_from_paper,ion_exchange_HPLC_LC_MS_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_CTRL_OLIGO_POS_LNA_GAPMER_SEQUENCE_PATTERN_HIGH_TOX,CTRL_OLIGO_POS_LNA_GAPMER_SEQUENCE_PATTERN_HIGH_TOX,HAGEDORN_LNA_HEPATOTOX_RF_2013,LNA,high_PS,0.98,high_PS,0,LNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_14,0.88,inferred_from_paper,ion_exchange_HPLC_LC_MS_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_CTRL_OLIGO_CONTEXT_DISTANCE_LIMITED_SEQUENCE_TOX_PREDICTION,CTRL_OLIGO_CONTEXT_DISTANCE_LIMITED_SEQUENCE_TOX_PREDICTION,HAGEDORN_LNA_HEPATOTOX_RF_2013,LNA,high_PS,0.88,high_PS,0,LNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_13,0.9,inferred_from_paper,ion_exchange_HPLC_LC_MS_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_CTRL_OLIGO_NEG_VIR2218_ESCPLUS_LOW_ALT,CTRL_OLIGO_NEG_VIR2218_ESCPLUS_LOW_ALT,GANE_VIR2218_ALNHBV_HBV_RNAI_2023,mixed_ESCplus_GNA_seed,partial_PS,0.22,low_PS,1,mixed_ESCplus_GNA_seed|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_4,0.978,inferred_from_paper,LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_CTRL_OLIGO_POS_ALNHBV_SEED_OFFTARGET_ALT,CTRL_OLIGO_POS_ALNHBV_SEED_OFFTARGET_ALT,GANE_VIR2218_ALNHBV_HBV_RNAI_2023,mixed_ESC_parent,partial_PS,0.28,low_PS,1,mixed_ESC_parent|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_6,0.972,inferred_from_paper,LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_CTRL_OLIGO_CONTEXT_VIR2218_CHBV_HBSAG_REDUCTION,CTRL_OLIGO_CONTEXT_VIR2218_CHBV_HBSAG_REDUCTION,GANE_VIR2218_ALNHBV_HBV_RNAI_2023,mixed_ESCplus_GNA_seed,partial_PS,0.22,low_PS,1,mixed_ESCplus_GNA_seed|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_4,0.978,inferred_from_paper,LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_CTRL_OLIGO_NEG_ZILEBESIRAN_GALNAC_AGT_PLATFORM,CTRL_OLIGO_NEG_ZILEBESIRAN_GALNAC_AGT_PLATFORM,DUDZICZ_ZILEBESIRAN_HTN_REVIEW_2025,mixed,partial_PS,0.18,low_PS,1,mixed|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_4,0.975,inferred_from_paper,HPLC+LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_CTRL_OLIGO_CONTEXT_ZILEBESIRAN_RAAS_MONITORING,CTRL_OLIGO_CONTEXT_ZILEBESIRAN_RAAS_MONITORING,DUDZICZ_ZILEBESIRAN_HTN_REVIEW_2025,mixed,partial_PS,0.18,low_PS,1,mixed|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_4,0.975,inferred_from_paper,HPLC+LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_CTRL_OLIGO_CONTEXT_ZILEBESIRAN_LONG_PD_DEPOT,CTRL_OLIGO_CONTEXT_ZILEBESIRAN_LONG_PD_DEPOT,DUDZICZ_ZILEBESIRAN_HTN_REVIEW_2025,mixed,partial_PS,0.16,low_PS,1,mixed|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_3,0.975,inferred_from_paper,HPLC+LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_CTRL_OLIGO_NEG_TTR_GALNAC_SIRNA_BULGE14_ACTIVE_LOW_TOX,CTRL_OLIGO_NEG_TTR_GALNAC_SIRNA_BULGE14_ACTIVE_LOW_TOX,HAUPTMANN_SIRNA_BULGES_GALNAC_2022,2OMe_2F_alternating,partial_PS,0.18,low_PS,1,2OMe_2F_alternating|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_3,0.92,inferred_from_paper,native_IP_RP_LCMS_melting_curve_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_CTRL_OLIGO_POS_TERMINAL_BULGE_OFFTARGET_REPRESSION_RISK,CTRL_OLIGO_POS_TERMINAL_BULGE_OFFTARGET_REPRESSION_RISK,HAUPTMANN_SIRNA_BULGES_GALNAC_2022,2OMe_2F_alternating,partial_PS,0.12,low_PS,0,2OMe_2F_alternating|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_2,0.91,inferred_from_paper,reporter_repression_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_CTRL_OLIGO_CONTEXT_SEED_REGION_BULGE_ACTIVITY_LOSS,CTRL_OLIGO_CONTEXT_SEED_REGION_BULGE_ACTIVITY_LOSS,HAUPTMANN_SIRNA_BULGES_GALNAC_2022,2OMe_2F_alternating,partial_PS,0.12,low_PS,0,2OMe_2F_alternating|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_2,0.91,inferred_from_paper,qRT_PCR_activity_screen_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_CTRL_OLIGO_CONTEXT_FBLL1_HIGH_HCC_MALIGNANT_STATE,CTRL_OLIGO_CONTEXT_FBLL1_HIGH_HCC_MALIGNANT_STATE,XIE_FBLL1_HCC_SPATIAL_MULTIOMICS_2026,not_applicable,low_or_no_PS,0.0,low_PS,0,not_applicable,not_applicable,0.0,inferred_from_paper,bulk_RNAseq_scRNAseq_spatial_transcriptomics_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_CTRL_OLIGO_NEG_FBLL1_SIRNA_KNOCKDOWN_HCC_GROWTH_SUPPRESSION,CTRL_OLIGO_NEG_FBLL1_SIRNA_KNOCKDOWN_HCC_GROWTH_SUPPRESSION,XIE_FBLL1_HCC_SPATIAL_MULTIOMICS_2026,unmodified_or_research_siRNA_proxy,low_or_no_PS,0.0,low_PS,0,unmodified_or_research_siRNA_proxy|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_0,0.9,inferred_from_paper,qRT_PCR_CCK8_colony_formation_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_CTRL_OLIGO_CONTEXT_FBLL1_CMYC_EGFR_MAPK_ACTIVATION,CTRL_OLIGO_CONTEXT_FBLL1_CMYC_EGFR_MAPK_ACTIVATION,XIE_FBLL1_HCC_SPATIAL_MULTIOMICS_2026,not_applicable,low_or_no_PS,0.0,low_PS,0,not_applicable,not_applicable,0.0,inferred_from_paper,RNAseq_qPCR_Western_blot_xenograft_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_CTRL_OLIGO_NEG_GALNAC_LNP_SIMKK4_BIOCOMPATIBLE_LOW_HEMOLYSIS,CTRL_OLIGO_NEG_GALNAC_LNP_SIMKK4_BIOCOMPATIBLE_LOW_HEMOLYSIS,ZHAI_GALNAC_LNP_SIMKK4_LIVER_REGEN_2026,synthetic_siRNA_payload_proxy,low_or_no_PS,0.0,low_PS,1,synthetic_siRNA_payload_proxy|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_0,0.92,inferred_from_paper,qRT_PCR_flow_CLSM_hemolysis_live_dead_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_CTRL_OLIGO_CONTEXT_GALNAC_LNP_SIMKK4_ACLF_REGENERATION,CTRL_OLIGO_CONTEXT_GALNAC_LNP_SIMKK4_ACLF_REGENERATION,ZHAI_GALNAC_LNP_SIMKK4_LIVER_REGEN_2026,synthetic_siRNA_payload_proxy,low_or_no_PS,0.0,low_PS,1,synthetic_siRNA_payload_proxy|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_0,0.9,inferred_from_paper,MicroCT_H_E_Ki67_TUNEL_biochemistry_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_CTRL_OLIGO_POS_CCL4_PHX_ACLF_INJURY_CONTEXT,CTRL_OLIGO_POS_CCL4_PHX_ACLF_INJURY_CONTEXT,ZHAI_GALNAC_LNP_SIMKK4_LIVER_REGEN_2026,not_applicable,low_or_no_PS,0.0,low_PS,0,not_applicable,not_applicable,0.0,inferred_from_paper,liver_injury_model_context_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_CTRL_OLIGO_POS_OGT_SEV_LSEC_CAPILLARIZATION_MASLD,CTRL_OLIGO_POS_OGT_SEV_LSEC_CAPILLARIZATION_MASLD,WANG_OGT_SEV_LSEC_MASLD_2026,not_applicable,low_or_no_PS,0.0,low_PS,0,not_applicable,not_applicable,0.0,inferred_from_paper,SEM_NTA_TEM_Western_ELISA_qPCR_IHC_SERUM_ALT_AST_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_CTRL_OLIGO_NEG_OGT_KNOCKDOWN_SEV_REDUCED_CAPILLARIZATION,CTRL_OLIGO_NEG_OGT_KNOCKDOWN_SEV_REDUCED_CAPILLARIZATION,WANG_OGT_SEV_LSEC_MASLD_2026,not_applicable,low_or_no_PS,0.0,low_PS,0,not_applicable,not_applicable,0.0,inferred_from_paper,OGT_knockdown_SEM_Western_ELISA_ALT_AST_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_CTRL_OLIGO_CONTEXT_BAGN_OGLCNAC_INHIBITOR_MASLD_RESCUE,CTRL_OLIGO_CONTEXT_BAGN_OGLCNAC_INHIBITOR_MASLD_RESCUE,WANG_OGT_SEV_LSEC_MASLD_2026,not_applicable,low_or_no_PS,0.0,low_PS,0,not_applicable,not_applicable,0.0,inferred_from_paper,Western_IF_SEM_ALT_AST_TG_inflammation_OilRed_Sirius_alphaSMA_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_CTRL_MALAT1_001,CTRL_MALAT1_001,DU_MALAT1_HBV_HCC_ASO_2025,ASO_proxy,partial_PS,0.65,medium_PS,0,ASO_proxy|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_12,0.91,inferred_from_paper,FISH_qRT_PCR_MeRIP_RIP_RNA_pulldown_ASO_intervention_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_CTRL_MALAT1_002,CTRL_MALAT1_002,DU_MALAT1_HBV_HCC_ASO_2025,ASO_proxy,partial_PS,0.65,medium_PS,0,ASO_proxy|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_12,0.91,inferred_from_paper,FISH_qRT_PCR_MeRIP_RIP_RNA_pulldown_ASO_intervention_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_CTRL_MALAT1_003,CTRL_MALAT1_003,DU_MALAT1_HBV_HCC_ASO_2025,ASO_proxy,partial_PS,0.65,medium_PS,0,ASO_proxy|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_12,0.91,inferred_from_paper,FISH_qRT_PCR_MeRIP_RIP_RNA_pulldown_ASO_intervention_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_CTRL_CD133_001,CTRL_CD133_001,PAN_CD133_MASLD_HCC_SIRNA_2025,2prime_OMe_pyrimidine_modified_siRNA_proxy,partial_PS,0.18,low_PS,0,2prime_OMe_pyrimidine_modified_siRNA_proxy|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_4,0.93,inferred_from_paper,lineage_tracing_scRNAseq_WB_IF_VNP_siRNA_combination_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_CTRL_CD133_002,CTRL_CD133_002,PAN_CD133_MASLD_HCC_SIRNA_2025,2prime_OMe_pyrimidine_modified_siRNA_proxy,partial_PS,0.18,low_PS,0,2prime_OMe_pyrimidine_modified_siRNA_proxy|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_4,0.93,inferred_from_paper,lineage_tracing_scRNAseq_WB_IF_VNP_siRNA_combination_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_CTRL_CD133_003,CTRL_CD133_003,PAN_CD133_MASLD_HCC_SIRNA_2025,2prime_OMe_pyrimidine_modified_siRNA_proxy,partial_PS,0.18,low_PS,0,2prime_OMe_pyrimidine_modified_siRNA_proxy|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_4,0.93,inferred_from_paper,lineage_tracing_scRNAseq_WB_IF_VNP_siRNA_combination_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_CTRL_GALNAC_RBC_EV_001,CTRL_GALNAC_RBC_EV_001,HUANG_GALNAC_RBC_EV_LIVER_DISEASE_2025,cholesterol_GalNAc_tethered_ASO_siRNA_proxy,partial_PS,0.2,low_PS,1,cholesterol_GalNAc_tethered_ASO_siRNA_proxy|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_4,0.93,inferred_from_paper,TEM_NTA_WB_flow_IVIS_ALT_AST_histology_WB_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_CTRL_GALNAC_RBC_EV_002,CTRL_GALNAC_RBC_EV_002,HUANG_GALNAC_RBC_EV_LIVER_DISEASE_2025,cholesterol_GalNAc_tethered_ASO_siRNA_proxy,partial_PS,0.2,low_PS,1,cholesterol_GalNAc_tethered_ASO_siRNA_proxy|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_4,0.93,inferred_from_paper,TEM_NTA_WB_flow_IVIS_ALT_AST_histology_WB_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_CTRL_GALNAC_RBC_EV_003,CTRL_GALNAC_RBC_EV_003,HUANG_GALNAC_RBC_EV_LIVER_DISEASE_2025,cholesterol_GalNAc_tethered_ASO_siRNA_proxy,partial_PS,0.2,low_PS,1,cholesterol_GalNAc_tethered_ASO_siRNA_proxy|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_4,0.93,inferred_from_paper,TEM_NTA_WB_flow_IVIS_ALT_AST_histology_WB_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_CTRL_GALNAC_RBC_EV_004,CTRL_GALNAC_RBC_EV_004,HUANG_GALNAC_RBC_EV_LIVER_DISEASE_2025,cholesterol_GalNAc_tethered_ASO_siRNA_proxy,partial_PS,0.2,low_PS,1,cholesterol_GalNAc_tethered_ASO_siRNA_proxy|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_4,0.93,inferred_from_paper,TEM_NTA_WB_flow_IVIS_ALT_AST_histology_WB_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_CTRL_MELDPLUS_001,CTRL_MELDPLUS_001,KARTOUN_MELD_PLUS_CIRRHOSIS_2017,not_applicable_clinical_risk_score_context,low_or_no_PS,0.0,low_PS,0,not_applicable,not_applicable,1.0,inferred_from_paper,EMR_structured_variables_logistic_regression_AUROC_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_CTRL_MELDPLUS_002,CTRL_MELDPLUS_002,KARTOUN_MELD_PLUS_CIRRHOSIS_2017,not_applicable_clinical_risk_score_context,low_or_no_PS,0.0,low_PS,0,not_applicable,not_applicable,1.0,inferred_from_paper,EMR_structured_variables_logistic_regression_AUROC_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_CTRL_MELDPLUS_003,CTRL_MELDPLUS_003,KARTOUN_MELD_PLUS_CIRRHOSIS_2017,not_applicable_clinical_risk_score_context,low_or_no_PS,0.0,low_PS,0,not_applicable,not_applicable,1.0,inferred_from_paper,EMR_structured_variables_logistic_regression_AUROC_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000000,OLIGO_0000000,JANAS_GALNAC_SIRNA_OFFTARGET_RAT_HEPATOTOX_2018,2prime_F,high_PS,0.7389,high_PS,0,2prime_F|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_18,0.96611,literature_grounded_generated,not_reported_generated,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000001,OLIGO_0000001,RAPIROSIRAN_SANYAL_2025,AmNA,low_or_no_PS,0.04775,low_PS,1,AmNA|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_1,0.98067,inferred_from_paper,LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000002,OLIGO_0000002,MA_HSD17B13_ASO_FIBROSIS_MOUSE_2024,LNA,low_or_no_PS,0.04378,low_PS,1,LNA|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_1,0.9427,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000003,OLIGO_0000003,TERADA_BROTHERS_ASO_PNA_TOEHOLD_2023,mixed,partial_PS,0.4101,medium_PS,0,mixed|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_8,0.95745,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000004,OLIGO_0000004,RAPIROSIRAN_SANYAL_2025,2prime_F,partial_PS,0.05867,low_PS,1,2prime_F|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_1,0.94384,inferred_from_paper,HPLC,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000005,OLIGO_0000005,HAUPTMANN_SIRNA_BULGES_GALNAC_2022,2OMe_2F_alternating,partial_PS,0.15482,low_PS,0,2OMe_2F_alternating|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_3,0.92561,inferred_from_paper,qRT_PCR_ELISA_reporter_melting_LCMS_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000006,OLIGO_0000006,PRAKASH_APOC3_LONG_ACTING_GALNAC_SIRNA_2025,2prime_F,partial_PS,0.0827,low_PS,0,2prime_F|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_2,0.99215,literature_grounded_generated,not_reported_generated,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000007,OLIGO_0000007,YAMAGUCHI_SCPBNA2_REDUCED_HEPATOTOX_2025,cEt,partial_PS,0.28455,low_PS,0,cEt|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_6,0.999,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000008,OLIGO_0000008,ABULHUSN_HSD17B13_PROTECTIVE_VARIANT_2018,2prime_F,partial_PS,0.09607,low_PS,0,2prime_F|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_2,0.93447,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000009,OLIGO_0000009,ABULHUSN_HSD17B13_PROTECTIVE_VARIANT_2018,mixed,partial_PS,0.08957,low_PS,0,mixed|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_2,0.97042,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000010,OLIGO_0000010,BI_IFNA_DISULFIDPTOSIS_HCC_2026,LNA,partial_PS,0.06829,low_PS,0,LNA|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_2,0.98965,literature_grounded_generated,IFN_alpha_disulfidptosis_context_nonreducing_WB_NADPH_Factin_siRNA_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000011,OLIGO_0000011,HJELMGREN_PS_ASO_DDR_2026,RNA_PS,high_PS,0.7,high_PS,1,RNA_PS|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_17,0.97848,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000012,OLIGO_0000012,HUANG_AGT_GALNAC_SIRNA_TOXICOLOGY_2025,mixed,partial_PS,0.53889,medium_PS,1,mixed|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_10,0.96865,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000013,OLIGO_0000013,ANDERSSON_PRECLINICAL_OLIGO_SAFETY_2022,cEt,partial_PS,0.21369,low_PS,1,cEt|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_4,0.95917,literature_grounded_generated,preclinical_safety_screening_cascade_ALT_AST_kidney_complement_platelet_offtarget_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000014,OLIGO_0000014,HAGEDORN_LNA_HEPATOTOX_RF_2013,LNA,high_PS,0.90363,high_PS,0,LNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_14,0.9159,inferred_from_paper,ion_exchange_HPLC_LC_MS_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000015,OLIGO_0000015,LU_SULT1B1_SE_MASLD_2026,2prime_OMe,partial_PS,0.30531,low_PS,0,2prime_OMe|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_9,0.97575,inferred_from_paper,HPLC+LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000016,OLIGO_0000016,JANAS_GALNAC_RNAI_NONCLINICAL_SAFETY_2018,mixed,partial_PS,0.23019,low_PS,0,mixed|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_6,0.99304,literature_grounded_generated,rat_monkey_repeat_dose_toxicology_platform_safety_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000017,OLIGO_0000017,WANG_OGT_SEV_LSEC_MASLD_2026,not_applicable,low_or_no_PS,0.0,low_PS,0,not_applicable,not_applicable,0.76698,inferred_from_paper,SEM_LSEC_fenestration_Ang2_ELISA_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000018,OLIGO_0000018,OLSON_CHOLANGIOCYTE_CHOLESTASIS_2025,mixed,partial_PS,0.30008,low_PS,1,mixed|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_8,0.95513,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000019,OLIGO_0000019,MA_HSD17B13_ASO_FIBROSIS_MOUSE_2024,2prime_MOE,partial_PS,0.15271,low_PS,0,2prime_MOE|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_3,0.96902,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000020,OLIGO_0000020,OOSTVEEN_ANGPTL3_LIVER_SAFETY_2023,2prime_MOE,high_PS,0.86272,high_PS,1,2prime_MOE|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_20,0.91928,inferred_from_paper,LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000021,OLIGO_0000021,JANAS_GALNAC_RNAI_NONCLINICAL_SAFETY_2018,unmodified,partial_PS,0.30128,low_PS,0,unmodified|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_5,0.999,literature_grounded_generated,rat_monkey_repeat_dose_toxicology_platform_safety_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000022,OLIGO_0000022,DEBACKER_GALNAC_LIVER_DELIVERY_REVIEW_2020,mixed,high_PS,0.73744,high_PS,0,mixed|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_18,0.92775,literature_grounded_generated,GalNAc_ASGPR_liver_delivery_review_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000023,OLIGO_0000023,WANG_PMEVL_SEV_SMALL_RNA_PCSK9_2026,not_applicable_sEV_payload_context,low_or_no_PS,0.0,low_PS,0,not_applicable_sEV_payload_context|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_0,0.97404,literature_grounded_generated,RT_qPCR_NTA_TEM_Western_RNase_protection_IVIS_ALT_AST_H_E_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000024,OLIGO_0000024,KIM_NANP_LIPID_LIVER_TARGETING_2026,unmodified,partial_PS,0.11394,low_PS,1,unmodified|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_3,0.93866,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000025,OLIGO_0000025,PRAKASH_APOC3_LONG_ACTING_GALNAC_SIRNA_2025,2prime_OMe,partial_PS,0.27835,low_PS,1,2prime_OMe|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_6,0.96766,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000026,OLIGO_0000026,JANAS_GALNAC_RNAI_NONCLINICAL_SAFETY_2018,2prime_F,partial_PS,0.17276,low_PS,0,2prime_F|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_3,0.96736,literature_grounded_generated,rat_monkey_repeat_dose_toxicology_platform_safety_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000027,OLIGO_0000027,OLSON_CHOLANGIOCYTE_CHOLESTASIS_2025,LNA,high_PS,0.83682,high_PS,0,LNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_18,0.91756,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000028,OLIGO_0000028,LU_SULT1B1_SE_MASLD_2026,mixed,partial_PS,0.62,medium_PS,0,mixed|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_12,0.95134,inferred_from_paper,LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000029,OLIGO_0000029,JANAS_GALNAC_RNAI_NONCLINICAL_SAFETY_2018,cEt,high_PS,0.91168,high_PS,0,cEt|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_26,0.99771,literature_grounded_generated,rat_monkey_repeat_dose_toxicology_platform_safety_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000030,OLIGO_0000030,RO7239958_GERETTI_2025,LNA,high_PS,0.95797,high_PS,1,LNA|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_19,0.94075,inferred_from_paper,HPLC+LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000031,OLIGO_0000031,MA_HSD17B13_ASO_FIBROSIS_MOUSE_2024,2prime_OMe,partial_PS,0.21429,low_PS,0,2prime_OMe|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_4,0.96951,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000032,OLIGO_0000032,ARMISEN_AZD2693_PNPLA3_ASO_MASH_2025,mixed,partial_PS,0.21521,low_PS,1,mixed|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_5,0.98828,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000033,OLIGO_0000033,LU_SULT1B1_SE_MASLD_2026,2prime_OMe,partial_PS,0.56574,medium_PS,0,2prime_OMe|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_11,0.999,inferred_from_paper,HPLC+LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000034,OLIGO_0000034,RO7239958_GERETTI_2025,mixed,partial_PS,0.45473,medium_PS,1,mixed|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_10,0.97743,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000035,OLIGO_0000035,ARMISEN_AZD2693_PNPLA3_ASO_MASH_2025,unmodified,partial_PS,0.39375,medium_PS,0,unmodified|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_10,0.999,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000036,OLIGO_0000036,CROOKE_RNA_TARGETED_THERAPEUTICS_2018,unmodified,partial_PS,0.53329,medium_PS,0,unmodified|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_10,0.96523,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000037,OLIGO_0000037,LIVER_SPHEROID_SCHOLTEN_2026,AmNA,partial_PS,0.39349,medium_PS,1,AmNA|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_9,0.9264,inferred_from_paper,HPLC,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000038,OLIGO_0000038,LIU_CYP2E1_LNP_APAP_AILI_2025,LNA,partial_PS,0.21249,low_PS,0,LNA|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_5,0.94514,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000039,OLIGO_0000039,PNPLA3_ROMEO_VALENTI_2025,2prime_OMe,partial_PS,0.60286,medium_PS,0,2prime_OMe|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_16,0.9379,inferred_from_paper,not_reported_generated,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000040,OLIGO_0000040,UMEZU_ORAL_MIR29A_LIVER_FIBROSIS_NA_2025,2prime_F,partial_PS,0.42286,medium_PS,1,2prime_F|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_8,0.95855,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000041,OLIGO_0000041,BOSCO_INCLISIRAN_FH_REALWORLD_2025,LNA,partial_PS,0.61053,medium_PS,1,LNA|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_14,0.96183,literature_grounded_generated,real_world_six_month_lipid_PWV_ALT_AST_CPK_monitoring_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000042,OLIGO_0000042,OLIVER_HILL_MODEL_SELECTION_NAT_2026,cEt,partial_PS,0.277,low_PS,0,cEt|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_5,0.98316,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000043,OLIGO_0000043,QU_CPG_ODN_APAP_TLR9_IRG1_2025,AmNA,partial_PS,0.07133,low_PS,1,AmNA|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_1,0.97931,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000044,OLIGO_0000044,AGARWAL_GALNAC_SIRNA_OFFTARGET_2025,LNA,partial_PS,0.06073,low_PS,0,LNA|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_2,0.95856,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000045,OLIGO_0000045,KIM_NANP_LIPID_LIVER_TARGETING_2026,LNA,partial_PS,0.27098,low_PS,0,LNA|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_5,0.96073,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000046,OLIGO_0000046,ARMISEN_AZD2693_PNPLA3_ASO_MASH_2025,AmNA,high_PS,0.79565,high_PS,0,AmNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_11,0.94171,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000047,OLIGO_0000047,KEATING_ASO_OBESITY_NAFLD_2022,2prime_MOE,partial_PS,0.55134,medium_PS,1,2prime_MOE|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_14,0.97832,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000048,OLIGO_0000048,ANDERSSON_PRECLINICAL_OLIGO_SAFETY_2022,LNA,partial_PS,0.11564,low_PS,1,LNA|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_3,0.96039,literature_grounded_generated,preclinical_safety_screening_cascade_ALT_AST_kidney_complement_platelet_offtarget_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000049,OLIGO_0000049,KARTOUN_MELD_PLUS_CIRRHOSIS_2017,not_applicable_clinical_risk_score_context,low_or_no_PS,0.0,low_PS,0,not_applicable,not_applicable,0.95947,inferred_from_paper,EMR_structured_variables_LASSO_logistic_regression_AUROC_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000050,OLIGO_0000050,LAN_SIRUBICON_ROS_GALNAC_MASH_2025,mixed_2prime_F_2prime_OMe_siRNA,partial_PS,0.28,low_PS,1,mixed_2prime_F_2prime_OMe_siRNA|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_4,0.96988,inferred_from_paper,nanoparticle_DLS_zeta_biodistribution_Rubicon_knockdown_ALT_AST_generated_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000051,OLIGO_0000051,LU_SULT1B1_SE_MASLD_2026,mixed,partial_PS,0.55505,medium_PS,0,mixed|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_12,0.94628,inferred_from_paper,not_reported_generated,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000052,OLIGO_0000052,ARMISEN_AZD2693_PNPLA3_ASO_MASH_2025,cEt,partial_PS,0.12924,low_PS,1,cEt|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_2,0.95228,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000053,OLIGO_0000053,BOSCO_INCLISIRAN_FH_REALWORLD_2025,2prime_OMe,low_or_no_PS,0.04817,low_PS,1,2prime_OMe|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_1,0.97021,literature_grounded_generated,real_world_six_month_lipid_PWV_ALT_AST_CPK_monitoring_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000054,OLIGO_0000054,HAUPTMANN_SIRNA_BULGES_GALNAC_2022,2OMe_2F_alternating,partial_PS,0.23737,low_PS,1,2OMe_2F_alternating|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_4,0.89482,inferred_from_paper,qRT_PCR_ELISA_reporter_melting_LCMS_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000055,OLIGO_0000055,JEON_COP1_HCC_LIPID_STEMNESS_SIRNA_2026,2prime_OMe,partial_PS,0.29579,low_PS,1,2prime_OMe|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_6,0.97332,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000056,OLIGO_0000056,LU_SULT1B1_SE_MASLD_2026,2prime_F,partial_PS,0.49128,medium_PS,0,2prime_F|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_10,0.94892,inferred_from_paper,HPLC+LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000057,OLIGO_0000057,RAPIROSIRAN_SANYAL_2025,2prime_F,high_PS,0.8281,high_PS,0,2prime_F|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_19,0.93071,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000058,OLIGO_0000058,BUREL_GAPMER_RNASEH1_LONG_PREMRNA_HEPATOTOX_2016,cEt,partial_PS,0.09798,low_PS,1,cEt|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_2,0.97788,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000059,OLIGO_0000059,KIM_LARP6_HSC_FIBROSIS_DSI_RNA_2026,2prime_OMe,partial_PS,0.42604,medium_PS,0,2prime_OMe|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_10,0.96046,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000060,OLIGO_0000060,AGARWAL_GALNAC_SIRNA_OFFTARGET_2025,LNA,partial_PS,0.53843,medium_PS,1,LNA|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_9,0.99546,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000061,OLIGO_0000061,PNPLA3_ROMEO_VALENTI_2025,2prime_MOE,partial_PS,0.56449,medium_PS,1,2prime_MOE|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_12,0.9301,inferred_from_paper,HPLC,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000062,OLIGO_0000062,HAGEDORN_LNA_HEPATOTOX_RF_2013,LNA,high_PS,0.86004,high_PS,0,LNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_12,0.87422,inferred_from_paper,ion_exchange_HPLC_LC_MS_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000063,OLIGO_0000063,ANDERSSON_PRECLINICAL_OLIGO_SAFETY_2022,unmodified,partial_PS,0.15321,low_PS,1,unmodified|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_3,0.92945,literature_grounded_generated,preclinical_safety_screening_cascade_ALT_AST_kidney_complement_platelet_offtarget_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000064,OLIGO_0000064,HJELMGREN_PS_ASO_DDR_2026,DNA_PS,high_PS,0.7,high_PS,1,DNA_PS|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_14,0.99849,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000065,OLIGO_0000065,PAN_CD133_MASLD_HCC_SIRNA_2025,2prime_OMe,partial_PS,0.12794,low_PS,0,2prime_OMe|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_3,0.93952,inferred_from_paper,lineage_tracing_scRNAseq_WB_IF_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000066,OLIGO_0000066,AGARWAL_GALNAC_SIRNA_OFFTARGET_2025,mixed,partial_PS,0.16335,low_PS,0,mixed|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_4,0.97333,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000067,OLIGO_0000067,HUANG_GALNAC_RBC_EV_LIVER_DISEASE_2025,ASO_anti_miR_proxy,partial_PS,0.08585,low_PS,1,not_applicable,not_applicable,0.89521,inferred_from_paper,Rab7_siRNA_PJ34_HCC_retention_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000068,OLIGO_0000068,ANDERSSON_PRECLINICAL_OLIGO_SAFETY_2022,2prime_F,partial_PS,0.44847,medium_PS,0,2prime_F|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_10,0.94472,literature_grounded_generated,preclinical_safety_screening_cascade_ALT_AST_kidney_complement_platelet_offtarget_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000069,OLIGO_0000069,KIM_LARP6_HSC_FIBROSIS_DSI_RNA_2026,AmNA,partial_PS,0.14364,low_PS,1,AmNA|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_4,0.97366,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000070,OLIGO_0000070,HAGEDORN_LNA_HEPATOTOX_RF_2013,LNA,high_PS,0.8462,high_PS,0,LNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_12,0.88753,inferred_from_paper,ion_exchange_HPLC_LC_MS_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000071,OLIGO_0000071,HAUPTMANN_SIRNA_BULGES_GALNAC_2022,2OMe_2F_alternating,partial_PS,0.09129,low_PS,0,2OMe_2F_alternating|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_2,0.90676,inferred_from_paper,qRT_PCR_ELISA_reporter_melting_LCMS_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000072,OLIGO_0000072,PAN_CD133_MASLD_HCC_SIRNA_2025,2prime_OMe_pyrimidine_modified_siRNA_proxy,partial_PS,0.20872,low_PS,0,2prime_OMe_pyrimidine_modified_siRNA_proxy|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_5,0.87381,inferred_from_paper,MYH9_beta_catenin_coIP_TOPflash_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000073,OLIGO_0000073,MOHAMED_NANOPARTICLE_HEPATITIS_2026,2prime_OMe,partial_PS,0.22363,low_PS,0,2prime_OMe|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_4,0.96196,inferred_from_paper,HPLC+LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000074,OLIGO_0000074,JANAS_GALNAC_RNAI_NONCLINICAL_SAFETY_2018,2prime_MOE,partial_PS,0.53322,medium_PS,1,2prime_MOE|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_15,0.98562,literature_grounded_generated,rat_monkey_repeat_dose_toxicology_platform_safety_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000075,OLIGO_0000075,KANDA_PCDHA11_AMNA_ASO_2024,AmNA,high_PS,1.0,high_PS,0,AmNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_17,0.9799,inferred_from_paper,AmNA_ASO_synthesis_HPLC_LCMS_qPCR_microarray_toxicology_generated_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000076,OLIGO_0000076,RAPIROSIRAN_SANYAL_2025,2prime_MOE,low_or_no_PS,0.01655,low_PS,1,2prime_MOE|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_0,0.9645,inferred_from_paper,mass_spectrometry,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000077,OLIGO_0000077,RO7239958_GERETTI_2025,LNA,high_PS,0.79688,high_PS,1,LNA|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_22,0.95781,inferred_from_paper,HPLC,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000078,OLIGO_0000078,OLIVER_HILL_MODEL_SELECTION_NAT_2026,2prime_OMe,partial_PS,0.47063,medium_PS,0,2prime_OMe|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_14,0.99159,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000079,OLIGO_0000079,HJELMGREN_PS_ASO_DDR_2026,2prime_MOE,high_PS,0.7,high_PS,0,2prime_MOE|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_16,0.94525,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000080,OLIGO_0000080,JANAS_GALNAC_RNAI_NONCLINICAL_SAFETY_2018,2prime_OMe,high_PS,0.76051,high_PS,0,2prime_OMe|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_16,0.94627,literature_grounded_generated,rat_monkey_repeat_dose_toxicology_platform_safety_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000081,OLIGO_0000081,BOSCO_INCLISIRAN_FH_REALWORLD_2025,2prime_OMe,partial_PS,0.12286,low_PS,0,2prime_OMe|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_2,0.999,literature_grounded_generated,real_world_six_month_lipid_PWV_ALT_AST_CPK_monitoring_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000082,OLIGO_0000082,QU_CPG_ODN_APAP_TLR9_IRG1_2025,2prime_F,partial_PS,0.11586,low_PS,1,2prime_F|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_2,0.94597,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000083,OLIGO_0000083,YAMAGUCHI_SCPBNA2_REDUCED_HEPATOTOX_2025,AmNA,partial_PS,0.51694,medium_PS,0,AmNA|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_10,0.97495,literature_grounded_generated,not_reported_generated,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000084,OLIGO_0000084,JANAS_GALNAC_SIRNA_OFFTARGET_RAT_HEPATOTOX_2018,LNA,high_PS,0.80102,high_PS,0,LNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_12,0.97097,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000085,OLIGO_0000085,LIVER_SPHEROID_SCHOLTEN_2026,AmNA,partial_PS,0.11791,low_PS,1,AmNA|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_2,0.95922,inferred_from_paper,LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000086,OLIGO_0000086,LIVER_SPHEROID_SCHOLTEN_2026,LNA,partial_PS,0.06176,low_PS,1,LNA|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_1,0.94183,literature_grounded_generated,IFN_alpha_disulfidptosis_context_nonreducing_WB_NADPH_Factin_siRNA_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000087,OLIGO_0000087,DUDZICZ_ZILEBESIRAN_HTN_REVIEW_2025,mixed,partial_PS,0.20462,low_PS,1,mixed|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_5,0.94793,inferred_from_paper,HPLC+LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000088,OLIGO_0000088,DEBACKER_GALNAC_LIVER_DELIVERY_REVIEW_2020,2prime_F,partial_PS,0.44082,medium_PS,0,2prime_F|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_10,0.94682,literature_grounded_generated,GalNAc_ASGPR_liver_delivery_review_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000089,OLIGO_0000089,WANG_OGT_SEV_LSEC_MASLD_2026,not_applicable,low_or_no_PS,0.0,low_PS,0,not_applicable,not_applicable,0.83875,inferred_from_paper,ALT_AST_TG_inflammation_histology_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000090,OLIGO_0000090,DUDZICZ_ZILEBESIRAN_HTN_REVIEW_2025,mixed,partial_PS,0.42,medium_PS,1,mixed|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_8,0.96213,inferred_from_paper,LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000091,OLIGO_0000091,PARK_ERBB2_APTAMER_PET_PK_2023,LNA,high_PS,0.74855,high_PS,1,LNA|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_17,0.96116,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000092,OLIGO_0000092,KIM_LARP6_HSC_FIBROSIS_DSI_RNA_2026,LNA,partial_PS,0.64312,medium_PS,1,LNA|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_18,0.9779,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000093,OLIGO_0000093,KANDA_PCDHA11_AMNA_ASO_2024,AmNA,high_PS,1.0,high_PS,0,AmNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_17,0.97542,inferred_from_paper,AmNA_ASO_synthesis_HPLC_LCMS_qPCR_microarray_toxicology_generated_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000094,OLIGO_0000094,ANDERSSON_PRECLINICAL_OLIGO_SAFETY_2022,AmNA,partial_PS,0.44144,medium_PS,0,AmNA|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_11,0.95585,literature_grounded_generated,preclinical_safety_screening_cascade_ALT_AST_kidney_complement_platelet_offtarget_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000095,OLIGO_0000095,YAMAGUCHI_SCPBNA2_REDUCED_HEPATOTOX_2025,unmodified,partial_PS,0.23377,low_PS,1,unmodified|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_6,0.96932,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000096,OLIGO_0000096,HUANG_GALNAC_RBC_EV_LIVER_DISEASE_2025,ASO_anti_miR_proxy,partial_PS,0.48136,medium_PS,1,ASO_anti_miR_proxy|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_10,0.99,inferred_from_paper,PARP1_PAR_ORO_steatosis_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000097,OLIGO_0000097,LAN_SIRUBICON_ROS_GALNAC_MASH_2025,mixed_2prime_F_2prime_OMe_siRNA,partial_PS,0.1185,low_PS,1,mixed_2prime_F_2prime_OMe_siRNA|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_2,0.93276,inferred_from_paper,nanoparticle_DLS_zeta_biodistribution_Rubicon_knockdown_ALT_AST_generated_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000098,OLIGO_0000098,RO7239958_GERETTI_2025,LNA,partial_PS,0.56533,medium_PS,1,LNA|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_14,0.92925,inferred_from_paper,HPLC,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000099,OLIGO_0000099,JANAS_GALNAC_RNAI_NONCLINICAL_SAFETY_2018,2prime_F,partial_PS,0.31258,low_PS,1,2prime_F|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_8,0.999,literature_grounded_generated,rat_monkey_repeat_dose_toxicology_platform_safety_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000100,OLIGO_0000100,OOSTVEEN_ANGPTL3_LIVER_SAFETY_2023,2prime_MOE,partial_PS,0.16769,low_PS,1,2prime_MOE|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_4,0.99704,inferred_from_paper,HPLC+LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000101,OLIGO_0000101,DHARA_LNA_PHOSPHOTHIOTRIESTER_SSO_CLICK_2025,AmNA,partial_PS,0.62794,medium_PS,1,AmNA|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_11,0.9748,literature_grounded_generated,not_reported_generated,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000102,OLIGO_0000102,ANDERSSON_PRECLINICAL_OLIGO_SAFETY_2022,unmodified,partial_PS,0.25024,low_PS,0,unmodified|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_5,0.98423,literature_grounded_generated,preclinical_safety_screening_cascade_ALT_AST_kidney_complement_platelet_offtarget_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000103,OLIGO_0000103,HUANG_AGT_GALNAC_SIRNA_TOXICOLOGY_2025,cEt,high_PS,0.88675,high_PS,0,cEt|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_16,0.94926,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000104,OLIGO_0000104,OLIVER_HILL_MODEL_SELECTION_NAT_2026,mixed,partial_PS,0.2153,low_PS,0,mixed|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_5,0.91963,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000105,OLIGO_0000105,JANAS_GALNAC_SIRNA_OFFTARGET_RAT_HEPATOTOX_2018,mixed,partial_PS,0.32935,low_PS,1,mixed|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_8,0.97211,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000106,OLIGO_0000106,PNPLA3_ROMEO_VALENTI_2025,mixed,high_PS,0.68031,high_PS,0,mixed|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_16,0.9556,inferred_from_paper,HPLC,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000107,OLIGO_0000107,HAGEDORN_LNA_HEPATOTOX_RF_2013,LNA,high_PS,0.88574,high_PS,0,LNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_12,0.94227,inferred_from_paper,ion_exchange_HPLC_LC_MS_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000108,OLIGO_0000108,JANAS_GALNAC_SIRNA_OFFTARGET_RAT_HEPATOTOX_2018,2prime_MOE,partial_PS,0.31236,low_PS,1,2prime_MOE|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_7,0.98801,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000109,OLIGO_0000109,DEBACKER_GALNAC_LIVER_DELIVERY_REVIEW_2020,AmNA,partial_PS,0.37063,medium_PS,1,AmNA|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_8,0.96284,literature_grounded_generated,GalNAc_ASGPR_liver_delivery_review_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000110,OLIGO_0000110,DU_MALAT1_HBV_HCC_ASO_2025,gapmer_like_ASO_proxy,partial_PS,0.39203,medium_PS,0,gapmer_like_ASO_proxy|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_7,0.97214,inferred_from_paper,qRT_PCR_FISH_MeRIP_RIP_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000111,OLIGO_0000111,AGARWAL_GALNAC_SIRNA_OFFTARGET_2025,unmodified,partial_PS,0.27699,low_PS,0,unmodified|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_7,0.93046,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000112,OLIGO_0000112,BOSCO_INCLISIRAN_FH_REALWORLD_2025,AmNA,high_PS,0.87345,high_PS,0,AmNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_20,0.95615,literature_grounded_generated,real_world_six_month_lipid_PWV_ALT_AST_CPK_monitoring_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000113,OLIGO_0000113,OLIVER_HILL_MODEL_SELECTION_NAT_2026,cEt,low_or_no_PS,0.03294,low_PS,1,cEt|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_1,0.97723,literature_grounded_generated,not_reported_generated,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000114,OLIGO_0000114,RAPIROSIRAN_SANYAL_2025,unmodified,partial_PS,0.153,low_PS,0,unmodified|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_3,0.90642,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000115,OLIGO_0000115,RO7239958_GERETTI_2025,LNA,high_PS,0.98363,high_PS,1,LNA|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_18,0.94618,inferred_from_paper,LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000116,OLIGO_0000116,LIVER_SPHEROID_SCHOLTEN_2026,LNA,high_PS,0.70677,high_PS,1,LNA|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_18,0.95604,inferred_from_paper,LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000117,OLIGO_0000117,HUANG_AGT_GALNAC_SIRNA_TOXICOLOGY_2025,LNA,partial_PS,0.58775,medium_PS,0,LNA|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_15,0.99699,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000118,OLIGO_0000118,ANDERSSON_PRECLINICAL_OLIGO_SAFETY_2022,2prime_F,partial_PS,0.40706,medium_PS,0,2prime_F|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_8,0.9682,literature_grounded_generated,preclinical_safety_screening_cascade_ALT_AST_kidney_complement_platelet_offtarget_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000119,OLIGO_0000119,PNPLA3_ROMEO_VALENTI_2025,2prime_OMe,partial_PS,0.29908,low_PS,1,2prime_OMe|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_6,0.96831,inferred_from_paper,HPLC,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000120,OLIGO_0000120,KIM_LARP6_HSC_FIBROSIS_DSI_RNA_2026,LNA,low_or_no_PS,0.0465,low_PS,0,LNA|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_1,0.93772,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000121,OLIGO_0000121,RO7239958_GERETTI_2025,LNA,partial_PS,0.45,medium_PS,1,LNA|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_10,0.92789,inferred_from_paper,HPLC,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000122,OLIGO_0000122,PRAKASH_APOC3_LONG_ACTING_GALNAC_SIRNA_2025,unmodified,partial_PS,0.31179,low_PS,1,unmodified|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_8,0.96045,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000123,OLIGO_0000123,RAPIROSIRAN_SANYAL_2025,mixed,partial_PS,0.16841,low_PS,1,mixed|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_4,0.92827,inferred_from_paper,HPLC,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000124,OLIGO_0000124,HUANG_GALNAC_RBC_EV_LIVER_DISEASE_2025,2prime_OMe_stabilized_siRNA_proxy,low_or_no_PS,0.02947,low_PS,1,2prime_OMe_stabilized_siRNA_proxy|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_1,0.95246,inferred_from_paper,PARP1_PAR_ORO_steatosis_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000125,OLIGO_0000125,BJD_BMP1_SHRNA_AAV_CCL4_FIBROSIS_CONTEXT,2prime_OMe,partial_PS,0.58067,medium_PS,0,2prime_OMe|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_14,0.95265,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000126,OLIGO_0000126,PRAKASH_APOC3_LONG_ACTING_GALNAC_SIRNA_2025,AmNA,partial_PS,0.55767,medium_PS,0,AmNA|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_14,0.96657,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000127,OLIGO_0000127,LIVER_SPHEROID_SCHOLTEN_2026,AmNA,partial_PS,0.11942,low_PS,1,AmNA|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_3,0.95783,inferred_from_paper,not_reported_generated,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000128,OLIGO_0000128,DEBACKER_GALNAC_LIVER_DELIVERY_REVIEW_2020,mixed,partial_PS,0.48219,medium_PS,0,mixed|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_11,0.94453,literature_grounded_generated,GalNAc_ASGPR_liver_delivery_review_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000129,OLIGO_0000129,LU_GT_MULTI_SIRNA_HCC_2025,AmNA,partial_PS,0.18749,low_PS,1,AmNA|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_4,0.999,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000130,OLIGO_0000130,OOSTVEEN_ANGPTL3_LIVER_SAFETY_2023,mixed,partial_PS,0.49658,medium_PS,1,mixed|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_10,0.96686,inferred_from_paper,HPLC+LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000131,OLIGO_0000131,ANDERSSON_PRECLINICAL_OLIGO_SAFETY_2022,cEt,partial_PS,0.10936,low_PS,0,cEt|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_3,0.94113,literature_grounded_generated,preclinical_safety_screening_cascade_ALT_AST_kidney_complement_platelet_offtarget_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000132,OLIGO_0000132,ENGELBEEN_ALK4_MUSCLE_SIRNA_2023,mixed,partial_PS,0.25299,low_PS,0,mixed|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_7,0.92658,inferred_from_paper,HPLC,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000133,OLIGO_0000133,JANAS_GALNAC_SIRNA_OFFTARGET_RAT_HEPATOTOX_2018,mixed,partial_PS,0.10745,low_PS,0,mixed|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_2,0.98509,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000134,OLIGO_0000134,WANG_OGT_SEV_LSEC_MASLD_2026,not_applicable,low_or_no_PS,0.0,low_PS,0,not_applicable,not_applicable,0.65449,inferred_from_paper,NTA_TEM_Western_sEV_marker_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000135,OLIGO_0000135,RO7239958_GERETTI_2025,LNA,high_PS,0.91722,high_PS,1,LNA|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_21,0.97878,inferred_from_paper,HPLC,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000136,OLIGO_0000136,LIVER_SPHEROID_SCHOLTEN_2026,AmNA,high_PS,0.74227,high_PS,1,AmNA|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_13,0.92971,inferred_from_paper,HPLC+LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000137,OLIGO_0000137,KIM_LARP6_HSC_FIBROSIS_DSI_RNA_2026,mixed,partial_PS,0.33268,low_PS,0,mixed|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_8,0.95245,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000138,OLIGO_0000138,EGLI_MANOHARAN_APPROVED_OLIGO_CHEMISTRY_2023,mixed,partial_PS,0.07881,low_PS,0,mixed|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_2,0.94783,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000139,OLIGO_0000139,ZHAI_GALNAC_LNP_SIMKK4_LIVER_REGEN_2026,synthetic_siRNA_payload_proxy,low_or_no_PS,0.0,low_PS,1,synthetic_siRNA_payload_proxy|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_0,0.92915,inferred_from_paper,MicroCT_H_E_Ki67_TUNEL_biochemistry_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000140,OLIGO_0000140,LIVER_SPHEROID_SCHOLTEN_2026,2prime_MOE,partial_PS,0.46233,medium_PS,1,2prime_MOE|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_12,0.97664,inferred_from_paper,LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000141,OLIGO_0000141,MOHAMED_NANOPARTICLE_HEPATITIS_2026,cEt,partial_PS,0.24151,low_PS,0,cEt|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_5,0.99694,inferred_from_paper,HPLC,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000142,OLIGO_0000142,BOSCO_INCLISIRAN_FH_REALWORLD_2025,2prime_F,partial_PS,0.30101,low_PS,0,2prime_F|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_8,0.97943,literature_grounded_generated,real_world_six_month_lipid_PWV_ALT_AST_CPK_monitoring_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000143,OLIGO_0000143,GANE_VIR2218_ALNHBV_HBV_RNAI_2023,mixed_ESC_parent,partial_PS,0.06378,low_PS,1,mixed_ESC_parent|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_1,0.95233,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000144,OLIGO_0000144,RAPIROSIRAN_SANYAL_2025,mixed,low_or_no_PS,0.00713,low_PS,1,mixed|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_0,0.93361,inferred_from_paper,HPLC,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000145,OLIGO_0000145,EGLI_MANOHARAN_APPROVED_OLIGO_CHEMISTRY_2023,2prime_MOE,partial_PS,0.41181,medium_PS,0,2prime_MOE|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_7,0.94949,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000146,OLIGO_0000146,RAPIROSIRAN_SANYAL_2025,2prime_OMe,partial_PS,0.06294,low_PS,0,2prime_OMe|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_1,0.95361,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000147,OLIGO_0000147,AGARWAL_GALNAC_SIRNA_OFFTARGET_2025,AmNA,partial_PS,0.2789,low_PS,0,AmNA|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_6,0.97366,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000148,OLIGO_0000148,MA_HSD17B13_ASO_FIBROSIS_MOUSE_2024,2prime_OMe,partial_PS,0.54914,medium_PS,0,2prime_OMe|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_14,0.999,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000149,OLIGO_0000149,RAPIROSIRAN_SANYAL_2025,2prime_F,partial_PS,0.22219,low_PS,1,2prime_F|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_6,0.97405,inferred_from_paper,mass_spectrometry,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000150,OLIGO_0000150,KEATING_ASO_OBESITY_NAFLD_2022,unmodified,partial_PS,0.27898,low_PS,1,unmodified|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_6,0.95338,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000151,OLIGO_0000151,RAPIROSIRAN_SANYAL_2025,LNA,partial_PS,0.17078,low_PS,1,LNA|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_4,0.999,inferred_from_paper,HPLC+LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000152,OLIGO_0000152,KIM_NANP_LIPID_LIVER_TARGETING_2026,mixed,high_PS,0.73063,high_PS,0,mixed|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_18,0.999,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000153,OLIGO_0000153,KARTOUN_MELD_PLUS_CIRRHOSIS_2017,not_applicable_clinical_risk_score_context,low_or_no_PS,0.0,low_PS,0,not_applicable,not_applicable,0.96198,inferred_from_paper,EMR_structured_variables_LASSO_logistic_regression_AUROC_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000154,OLIGO_0000154,SCHLEGEL_ESCPLUS_SEED_PAIRING_GALNAC_SIRNA_2022,2prime_F,partial_PS,0.478,medium_PS,0,2prime_F|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_9,0.97481,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000155,OLIGO_0000155,HUANG_GALNAC_RBC_EV_LIVER_DISEASE_2025,cholesterol_GalNAc_tethered_oligo_proxy,low_or_no_PS,0.04892,low_PS,1,not_applicable,not_applicable,0.89485,inferred_from_paper,TEM_NTA_WB_flow_uptake_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000156,OLIGO_0000156,MA_HSD17B13_ASO_FIBROSIS_MOUSE_2024,unmodified,low_or_no_PS,0.04147,low_PS,0,unmodified|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_1,0.9696,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000157,OLIGO_0000157,LIU_CYP2E1_LNP_APAP_AILI_2025,unmodified,partial_PS,0.08492,low_PS,0,unmodified|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_2,0.94534,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000158,OLIGO_0000158,ENGELBEEN_ALK4_MUSCLE_SIRNA_2023,mixed,partial_PS,0.31759,low_PS,0,mixed|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_6,0.93864,inferred_from_paper,not_reported_generated,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000159,OLIGO_0000159,DEBACKER_GALNAC_LIVER_DELIVERY_REVIEW_2020,mixed,partial_PS,0.55337,medium_PS,1,mixed|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_11,0.95673,literature_grounded_generated,GalNAc_ASGPR_liver_delivery_review_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000160,OLIGO_0000160,RAPIROSIRAN_SANYAL_2025,2prime_F,partial_PS,0.17455,low_PS,1,2prime_F|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_4,0.97655,inferred_from_paper,HPLC+LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000161,OLIGO_0000161,RAPIROSIRAN_SANYAL_2025,2prime_OMe,partial_PS,0.10555,low_PS,1,2prime_OMe|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_3,0.93793,inferred_from_paper,HPLC,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000162,OLIGO_0000162,HUANG_AGT_GALNAC_SIRNA_TOXICOLOGY_2025,unmodified,partial_PS,0.26852,low_PS,0,unmodified|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_5,0.91699,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000163,OLIGO_0000163,UMEZU_ORAL_MIR29A_LIVER_FIBROSIS_NA_2025,unmodified,partial_PS,0.123,low_PS,0,unmodified|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_3,0.97944,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000164,OLIGO_0000164,RO7239958_GERETTI_2025,cEt,high_PS,0.67746,high_PS,1,cEt|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_14,0.95641,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000165,OLIGO_0000165,KIM_NANP_LIPID_LIVER_TARGETING_2026,AmNA,partial_PS,0.25356,low_PS,0,AmNA|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_7,0.9585,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000166,OLIGO_0000166,RAPIROSIRAN_SANYAL_2025,2prime_MOE,low_or_no_PS,0.03129,low_PS,1,2prime_MOE|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_1,0.97431,inferred_from_paper,HPLC+LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000167,OLIGO_0000167,BI_IFNA_DISULFIDPTOSIS_HCC_2026,AmNA,partial_PS,0.19467,low_PS,0,AmNA|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_6,0.98161,literature_grounded_generated,IFN_alpha_disulfidptosis_context_nonreducing_WB_NADPH_Factin_siRNA_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000168,OLIGO_0000168,RAPIROSIRAN_SANYAL_2025,2prime_MOE,partial_PS,0.1942,low_PS,1,2prime_MOE|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_5,0.94494,inferred_from_paper,not_reported_generated,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000169,OLIGO_0000169,LIVER_SPHEROID_SCHOLTEN_2026,LNA,partial_PS,0.25632,low_PS,1,LNA|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_7,0.99093,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000170,OLIGO_0000170,ARMISEN_AZD2693_PNPLA3_ASO_MASH_2025,LNA,high_PS,0.88031,high_PS,1,LNA|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_17,0.999,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000171,OLIGO_0000171,YAMAGUCHI_SCPBNA2_REDUCED_HEPATOTOX_2025,unmodified,partial_PS,0.23589,low_PS,1,unmodified|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_5,0.9573,literature_grounded_generated,not_reported_generated,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000172,OLIGO_0000172,JANAS_GALNAC_SIRNA_OFFTARGET_RAT_HEPATOTOX_2018,2prime_MOE,partial_PS,0.06822,low_PS,0,2prime_MOE|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_2,0.96464,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000173,OLIGO_0000173,AGARWAL_GALNAC_SIRNA_OFFTARGET_2025,cEt,partial_PS,0.21922,low_PS,1,cEt|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_5,0.95387,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000174,OLIGO_0000174,SOUSA_HDO_MULTIFUNCTIONAL_HELA_2022,2prime_F,low_or_no_PS,0.02228,low_PS,0,2prime_F|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_1,0.95461,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000175,OLIGO_0000175,MA_HSD17B13_ASO_FIBROSIS_MOUSE_2024,2prime_OMe,partial_PS,0.35817,medium_PS,0,2prime_OMe|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_9,0.94729,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000176,OLIGO_0000176,JANAS_GALNAC_SIRNA_OFFTARGET_RAT_HEPATOTOX_2018,mixed,high_PS,0.87584,high_PS,1,mixed|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_14,0.95771,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000177,OLIGO_0000177,HUANG_GALNAC_RBC_EV_LIVER_DISEASE_2025,cholesterol_GalNAc_tethered_oligo_proxy,partial_PS,0.1041,low_PS,1,not_applicable,not_applicable,0.96254,inferred_from_paper,ALT_AST_ELISA_H_E_IHC_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000178,OLIGO_0000178,DEBACKER_GALNAC_LIVER_DELIVERY_REVIEW_2020,LNA,partial_PS,0.24566,low_PS,0,LNA|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_4,0.97756,literature_grounded_generated,GalNAc_ASGPR_liver_delivery_review_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000179,OLIGO_0000179,JIANG_AOC_FREE_ASO_PAYLOAD_HYBRIDIZATION_LCMS_2024,LNA,high_PS,0.80107,high_PS,1,LNA|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_20,0.94918,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000180,OLIGO_0000180,ARMISEN_AZD2693_PNPLA3_ASO_MASH_2025,2prime_F,high_PS,0.94873,high_PS,0,2prime_F|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_17,0.97477,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000181,OLIGO_0000181,RAPIROSIRAN_SANYAL_2025,unmodified,partial_PS,0.14985,low_PS,1,unmodified|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_4,0.96509,inferred_from_paper,mass_spectrometry,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000182,OLIGO_0000182,QU_CPG_ODN_APAP_TLR9_IRG1_2025,2prime_OMe,high_PS,0.76697,high_PS,0,2prime_OMe|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_22,0.95804,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000183,OLIGO_0000183,KANDA_PCDHA11_AMNA_ASO_2024,AmNA,high_PS,1.0,high_PS,0,AmNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_15,0.98668,inferred_from_paper,AmNA_ASO_synthesis_HPLC_LCMS_qPCR_microarray_toxicology_generated_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000184,OLIGO_0000184,HAGEDORN_LNA_HEPATOTOX_RF_2013,LNA,high_PS,0.88706,high_PS,0,LNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_12,0.93282,inferred_from_paper,ion_exchange_HPLC_LC_MS_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000185,OLIGO_0000185,SUN_HCC_RNA_NANOPARTICLE_MULTITARGET_2026,2prime_MOE,high_PS,0.88965,high_PS,1,2prime_MOE|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_13,0.98576,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000186,OLIGO_0000186,ALSHAER_FDA_TIDES_HARVEST_2025,AmNA,partial_PS,0.2414,low_PS,0,AmNA|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_5,0.999,literature_grounded_generated,not_reported_generated,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000187,OLIGO_0000187,HAGEDORN_LNA_HEPATOTOX_RF_2013,LNA,high_PS,0.80857,high_PS,0,LNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_10,0.85677,inferred_from_paper,ion_exchange_HPLC_LC_MS_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000188,OLIGO_0000188,LAN_SIRUBICON_ROS_GALNAC_MASH_2025,mixed_2prime_F_2prime_OMe_siRNA,partial_PS,0.26975,low_PS,1,mixed_2prime_F_2prime_OMe_siRNA|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_6,0.96248,inferred_from_paper,nanoparticle_DLS_zeta_biodistribution_Rubicon_knockdown_ALT_AST_generated_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000189,OLIGO_0000189,ALSHAER_FDA_TIDES_HARVEST_2025,cEt,partial_PS,0.53113,medium_PS,0,cEt|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_13,0.96307,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000190,OLIGO_0000190,YAMAGUCHI_SCPBNA2_REDUCED_HEPATOTOX_2025,2prime_F,high_PS,0.73699,high_PS,1,2prime_F|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_13,0.98044,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000191,OLIGO_0000191,EGLI_MANOHARAN_APPROVED_OLIGO_CHEMISTRY_2023,LNA,partial_PS,0.64997,medium_PS,0,LNA|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_14,0.95573,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000192,OLIGO_0000192,KIM_LARP6_HSC_FIBROSIS_DSI_RNA_2026,2prime_OMe,partial_PS,0.1135,low_PS,0,2prime_OMe|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_2,0.96468,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000193,OLIGO_0000193,KANDA_PCDHA11_AMNA_ASO_2024,AmNA,high_PS,1.0,high_PS,0,AmNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_19,0.97572,inferred_from_paper,AmNA_ASO_synthesis_HPLC_LCMS_qPCR_microarray_toxicology_generated_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000194,OLIGO_0000194,AGARWAL_GALNAC_SIRNA_OFFTARGET_2025,LNA,partial_PS,0.45195,medium_PS,1,LNA|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_9,0.98521,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000195,OLIGO_0000195,DHARA_LNA_PHOSPHOTHIOTRIESTER_SSO_CLICK_2025,2prime_OMe,partial_PS,0.05585,low_PS,0,2prime_OMe|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_1,0.97185,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000196,OLIGO_0000196,RAPIROSIRAN_SANYAL_2025,mixed,partial_PS,0.06394,low_PS,1,mixed|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_1,0.97906,inferred_from_paper,HPLC+LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000197,OLIGO_0000197,HUANG_AGT_GALNAC_SIRNA_TOXICOLOGY_2025,2prime_F,high_PS,0.67796,high_PS,0,2prime_F|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_17,0.97739,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000198,OLIGO_0000198,SUN_HCC_RNA_NANOPARTICLE_MULTITARGET_2026,LNA,partial_PS,0.26355,low_PS,1,LNA|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_6,0.99784,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000199,OLIGO_0000199,MOHAMED_NANOPARTICLE_HEPATITIS_2026,2prime_F,partial_PS,0.33474,medium_PS,1,2prime_F|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_7,0.97298,inferred_from_paper,mass_spectrometry,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000200,OLIGO_0000200,LIVER_SPHEROID_SCHOLTEN_2026,AmNA,partial_PS,0.23379,low_PS,0,AmNA|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_6,0.99787,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000201,OLIGO_0000201,ABULHUSN_HSD17B13_PROTECTIVE_VARIANT_2018,2prime_OMe,partial_PS,0.0833,low_PS,0,2prime_OMe|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_1,0.97748,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000202,OLIGO_0000202,HAGEDORN_LNA_HEPATOTOX_RF_2013,LNA,high_PS,0.87464,high_PS,0,LNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_13,0.9016,inferred_from_paper,ion_exchange_HPLC_LC_MS_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000203,OLIGO_0000203,ZHAI_GALNAC_LNP_SIMKK4_LIVER_REGEN_2026,synthetic_siRNA_payload_proxy,low_or_no_PS,0.0,low_PS,1,synthetic_siRNA_payload_proxy|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_0,0.97024,inferred_from_paper,Western_IF_p38_JNK_ATF2_ELK1_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000204,OLIGO_0000204,LU_SULT1B1_SE_MASLD_2026,2prime_OMe,partial_PS,0.31289,low_PS,0,2prime_OMe|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_8,0.96112,inferred_from_paper,HPLC+LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000205,OLIGO_0000205,HUANG_GALNAC_RBC_EV_LIVER_DISEASE_2025,2prime_OMe_stabilized_siRNA_proxy,partial_PS,0.06338,low_PS,1,2prime_OMe_stabilized_siRNA_proxy|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_1,0.95586,inferred_from_paper,Rab7_siRNA_PJ34_HCC_retention_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000206,OLIGO_0000206,PARK_ERBB2_APTAMER_PET_PK_2023,cEt,high_PS,0.8848,high_PS,0,cEt|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_14,0.99392,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000207,OLIGO_0000207,GANE_VIR2218_ALNHBV_HBV_RNAI_2023,mixed_ESCplus_GNA_seed,partial_PS,0.26057,low_PS,1,mixed_ESCplus_GNA_seed|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_5,0.93064,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000208,OLIGO_0000208,LIVER_SPHEROID_SCHOLTEN_2026,2prime_OMe,partial_PS,0.3664,medium_PS,1,2prime_OMe|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_7,0.96812,inferred_from_paper,LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000209,OLIGO_0000209,KIM_LARP6_HSC_FIBROSIS_DSI_RNA_2026,AmNA,partial_PS,0.31769,low_PS,0,AmNA|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_7,0.99868,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000210,OLIGO_0000210,RAPIROSIRAN_SANYAL_2025,unmodified,partial_PS,0.33979,medium_PS,1,unmodified|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_9,0.99618,inferred_from_paper,HPLC+LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000211,OLIGO_0000211,AGARWAL_GALNAC_SIRNA_OFFTARGET_2025,unmodified,partial_PS,0.09799,low_PS,1,unmodified|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_2,0.999,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000212,OLIGO_0000212,ARMISEN_AZD2693_PNPLA3_ASO_MASH_2025,AmNA,partial_PS,0.45093,medium_PS,1,AmNA|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_11,0.96492,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000213,OLIGO_0000213,JANAS_GALNAC_SIRNA_OFFTARGET_RAT_HEPATOTOX_2018,LNA,partial_PS,0.18645,low_PS,1,LNA|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_4,0.99576,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000214,OLIGO_0000214,DEBACKER_GALNAC_LIVER_DELIVERY_REVIEW_2020,2prime_F,partial_PS,0.3896,medium_PS,0,2prime_F|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_7,0.95759,literature_grounded_generated,GalNAc_ASGPR_liver_delivery_review_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000215,OLIGO_0000215,LIVER_SPHEROID_SCHOLTEN_2026,mixed,partial_PS,0.48902,medium_PS,1,mixed|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_11,0.95969,inferred_from_paper,HPLC+LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000216,OLIGO_0000216,OLSON_CHOLANGIOCYTE_CHOLESTASIS_2025,LNA,partial_PS,0.22668,low_PS,0,LNA|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_5,0.999,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000217,OLIGO_0000217,LAN_SIRUBICON_ROS_GALNAC_MASH_2025,mixed_2prime_F_2prime_OMe_siRNA,partial_PS,0.28,low_PS,1,mixed_2prime_F_2prime_OMe_siRNA|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_7,0.94484,inferred_from_paper,nanoparticle_DLS_zeta_biodistribution_Rubicon_knockdown_ALT_AST_generated_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000218,OLIGO_0000218,JANAS_GALNAC_SIRNA_OFFTARGET_RAT_HEPATOTOX_2018,2prime_MOE,partial_PS,0.36477,medium_PS,0,2prime_MOE|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_8,0.98048,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000219,OLIGO_0000219,OOSTVEEN_ANGPTL3_LIVER_SAFETY_2023,2prime_OMe,partial_PS,0.22107,low_PS,1,2prime_OMe|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_5,0.9878,inferred_from_paper,not_reported_generated,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000220,OLIGO_0000220,LU_SULT1B1_SE_MASLD_2026,2prime_OMe,partial_PS,0.41137,medium_PS,0,2prime_OMe|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_9,0.90681,inferred_from_paper,HPLC+LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000221,OLIGO_0000221,OLIVER_HILL_MODEL_SELECTION_NAT_2026,unmodified,partial_PS,0.56895,medium_PS,0,unmodified|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_13,0.96376,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000222,OLIGO_0000222,HJELMGREN_PS_ASO_DDR_2026,LNA_mixed,high_PS,0.7,high_PS,0,LNA_mixed|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_18,0.99638,literature_grounded_generated,IFN_alpha_disulfidptosis_context_nonreducing_WB_NADPH_Factin_siRNA_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000223,OLIGO_0000223,EGLI_MANOHARAN_APPROVED_OLIGO_CHEMISTRY_2023,cEt,partial_PS,0.41872,medium_PS,0,cEt|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_8,0.93353,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000224,OLIGO_0000224,OLSON_CHOLANGIOCYTE_CHOLESTASIS_2025,LNA,partial_PS,0.28243,low_PS,1,LNA|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_5,0.9747,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000225,OLIGO_0000225,RAPIROSIRAN_SANYAL_2025,2prime_F,partial_PS,0.09367,low_PS,1,2prime_F|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_2,0.95421,inferred_from_paper,LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000226,OLIGO_0000226,SUBRAMANIAN_RNAI_RHEOSTAT_AAV_TRANSGENE_2023,unmodified,partial_PS,0.62558,medium_PS,1,unmodified|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_16,0.98202,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000227,OLIGO_0000227,OLSON_CHOLANGIOCYTE_CHOLESTASIS_2025,2prime_F,partial_PS,0.21291,low_PS,1,2prime_F|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_5,0.96662,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000228,OLIGO_0000228,HJELMGREN_PS_ASO_DDR_2026,2prime_MOE,high_PS,0.7,high_PS,0,2prime_MOE|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_16,0.93577,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000229,OLIGO_0000229,ANDERSSON_PRECLINICAL_OLIGO_SAFETY_2022,2prime_MOE,partial_PS,0.21558,low_PS,0,2prime_MOE|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_5,0.97788,literature_grounded_generated,preclinical_safety_screening_cascade_ALT_AST_kidney_complement_platelet_offtarget_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000230,OLIGO_0000230,AGARWAL_GALNAC_SIRNA_OFFTARGET_2025,2prime_OMe,partial_PS,0.34789,medium_PS,1,2prime_OMe|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_7,0.9789,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000231,OLIGO_0000231,LIU_CYP2E1_LNP_APAP_AILI_2025,AmNA,partial_PS,0.60867,medium_PS,1,AmNA|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_15,0.98633,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000232,OLIGO_0000232,HJELMGREN_PS_ASO_DDR_2026,LNA_mixed,high_PS,0.7,high_PS,0,LNA_mixed|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_15,0.99138,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000233,OLIGO_0000233,JANAS_GALNAC_RNAI_NONCLINICAL_SAFETY_2018,2prime_MOE,partial_PS,0.65846,medium_PS,0,2prime_MOE|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_13,0.96944,literature_grounded_generated,rat_monkey_repeat_dose_toxicology_platform_safety_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000234,OLIGO_0000234,ARMISEN_AZD2693_PNPLA3_ASO_MASH_2025,mixed,partial_PS,0.53589,medium_PS,0,mixed|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_12,0.95961,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000235,OLIGO_0000235,KEATING_ASO_OBESITY_NAFLD_2022,2prime_OMe,partial_PS,0.3979,medium_PS,0,2prime_OMe|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_10,0.99352,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000236,OLIGO_0000236,MA_HSD17B13_ASO_FIBROSIS_MOUSE_2024,unmodified,partial_PS,0.44722,medium_PS,0,unmodified|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_10,0.93187,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000237,OLIGO_0000237,KARTOUN_MELD_PLUS_CIRRHOSIS_2017,not_applicable_clinical_risk_score_context,low_or_no_PS,0.0,low_PS,0,not_applicable,not_applicable,0.96965,inferred_from_paper,EMR_structured_variables_LASSO_logistic_regression_AUROC_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000238,OLIGO_0000238,DEBACKER_GALNAC_LIVER_DELIVERY_REVIEW_2020,2prime_F,partial_PS,0.18801,low_PS,1,2prime_F|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_3,0.96785,literature_grounded_generated,GalNAc_ASGPR_liver_delivery_review_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000239,OLIGO_0000239,JANAS_GALNAC_RNAI_NONCLINICAL_SAFETY_2018,2prime_MOE,partial_PS,0.23834,low_PS,0,2prime_MOE|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_5,0.92288,literature_grounded_generated,rat_monkey_repeat_dose_toxicology_platform_safety_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000240,OLIGO_0000240,SUBRAMANIAN_RNAI_RHEOSTAT_AAV_TRANSGENE_2023,LNA,partial_PS,0.17702,low_PS,0,LNA|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_4,0.98882,literature_grounded_generated,not_reported_generated,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000241,OLIGO_0000241,JANAS_GALNAC_SIRNA_OFFTARGET_RAT_HEPATOTOX_2018,2prime_F,partial_PS,0.0501,low_PS,1,2prime_F|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_1,0.95226,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000242,OLIGO_0000242,HUANG_AGT_GALNAC_SIRNA_TOXICOLOGY_2025,LNA,partial_PS,0.57309,medium_PS,0,LNA|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_8,0.98466,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000243,OLIGO_0000243,MA_HSD17B13_ASO_FIBROSIS_MOUSE_2024,AmNA,partial_PS,0.07399,low_PS,1,AmNA|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_1,0.9856,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000244,OLIGO_0000244,KANDA_PCDHA11_AMNA_ASO_2024,AmNA,high_PS,1.0,high_PS,0,AmNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_17,0.99279,inferred_from_paper,AmNA_ASO_synthesis_HPLC_LCMS_qPCR_microarray_toxicology_generated_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000245,OLIGO_0000245,LIVER_SPHEROID_SCHOLTEN_2026,LNA,partial_PS,0.50077,medium_PS,1,LNA|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_11,0.94163,inferred_from_paper,HPLC,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000246,OLIGO_0000246,HJELMGREN_PS_ASO_DDR_2026,LNA_mixed,high_PS,0.7,high_PS,0,LNA_mixed|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_14,0.91288,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000247,OLIGO_0000247,JANAS_GALNAC_SIRNA_OFFTARGET_RAT_HEPATOTOX_2018,unmodified,partial_PS,0.17436,low_PS,0,unmodified|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_4,0.97161,literature_grounded_generated,not_reported_generated,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000248,OLIGO_0000248,LIVER_SPHEROID_SCHOLTEN_2026,mixed,high_PS,0.77588,high_PS,1,mixed|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_20,0.96119,inferred_from_paper,HPLC,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000249,OLIGO_0000249,SCHLEGEL_ESCPLUS_SEED_PAIRING_GALNAC_SIRNA_2022,LNA,partial_PS,0.08863,low_PS,0,LNA|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_2,0.95583,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000250,OLIGO_0000250,JANAS_GALNAC_SIRNA_OFFTARGET_RAT_HEPATOTOX_2018,2prime_MOE,partial_PS,0.25293,low_PS,1,2prime_MOE|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_5,0.96324,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000251,OLIGO_0000251,RO7239958_GERETTI_2025,2prime_MOE,partial_PS,0.23178,low_PS,1,2prime_MOE|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_6,0.98151,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000252,OLIGO_0000252,BERGEN_DILIMAP_TOXPREDICTOR_DILI_2025,2prime_F,high_PS,0.8076,high_PS,0,2prime_F|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_13,0.95774,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000253,OLIGO_0000253,HJELMGREN_PS_ASO_DDR_2026,2prime_MOE,high_PS,0.77507,high_PS,0,2prime_MOE|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_17,0.95599,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000254,OLIGO_0000254,BUREL_GAPMER_RNASEH1_LONG_PREMRNA_HEPATOTOX_2016,2prime_MOE,partial_PS,0.50994,medium_PS,1,2prime_MOE|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_13,0.98511,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000255,OLIGO_0000255,OLSON_CHOLANGIOCYTE_CHOLESTASIS_2025,mixed,partial_PS,0.28729,low_PS,0,mixed|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_6,0.93718,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000256,OLIGO_0000256,HAGEDORN_LNA_HEPATOTOX_RF_2013,LNA,high_PS,0.87635,high_PS,0,LNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_11,0.8721,inferred_from_paper,ion_exchange_HPLC_LC_MS_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000257,OLIGO_0000257,BOSCO_INCLISIRAN_FH_REALWORLD_2025,cEt,partial_PS,0.19475,low_PS,0,cEt|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_4,0.999,literature_grounded_generated,real_world_six_month_lipid_PWV_ALT_AST_CPK_monitoring_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000258,OLIGO_0000258,TERADA_BROTHERS_ASO_PNA_TOEHOLD_2023,mixed,partial_PS,0.43196,medium_PS,0,mixed|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_10,0.95845,literature_grounded_generated,not_reported_generated,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000259,OLIGO_0000259,LIVER_SPHEROID_SCHOLTEN_2026,2prime_OMe,partial_PS,0.19113,low_PS,1,2prime_OMe|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_4,0.999,inferred_from_paper,HPLC,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000260,OLIGO_0000260,RAPIROSIRAN_SANYAL_2025,cEt,partial_PS,0.45063,medium_PS,1,cEt|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_12,0.96336,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000261,OLIGO_0000261,BUREL_GAPMER_RNASEH1_LONG_PREMRNA_HEPATOTOX_2016,2prime_OMe,partial_PS,0.32496,low_PS,0,2prime_OMe|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_6,0.98141,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000262,OLIGO_0000262,HAGEDORN_LNA_HEPATOTOX_RF_2013,LNA,high_PS,0.93305,high_PS,0,LNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_12,0.90685,inferred_from_paper,ion_exchange_HPLC_LC_MS_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000263,OLIGO_0000263,HAGEDORN_LNA_HEPATOTOX_RF_2013,LNA,high_PS,0.82528,high_PS,0,LNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_10,0.86419,inferred_from_paper,ion_exchange_HPLC_LC_MS_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000264,OLIGO_0000264,DEBACKER_GALNAC_LIVER_DELIVERY_REVIEW_2020,mixed,high_PS,0.76581,high_PS,0,mixed|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_16,0.97568,literature_grounded_generated,GalNAc_ASGPR_liver_delivery_review_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000265,OLIGO_0000265,YANG_PIRNA_CANCER_DIAGNOSTIC_THERAPEUTIC_REVIEW_2026,2prime_F,partial_PS,0.19383,low_PS,1,2prime_F|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_4,0.9763,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000266,OLIGO_0000266,RAPIROSIRAN_SANYAL_2025,LNA,partial_PS,0.05775,low_PS,1,LNA|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_2,0.95696,inferred_from_paper,LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000267,OLIGO_0000267,PRAKASH_APOC3_LONG_ACTING_GALNAC_SIRNA_2025,unmodified,low_or_no_PS,0.0253,low_PS,0,unmodified|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_1,0.98521,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000268,OLIGO_0000268,RO7239958_GERETTI_2025,2prime_F,partial_PS,0.05072,low_PS,1,2prime_F|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_1,0.91939,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000269,OLIGO_0000269,MOHAMED_NANOPARTICLE_HEPATITIS_2026,cEt,low_or_no_PS,0.04089,low_PS,1,cEt|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_1,0.93944,inferred_from_paper,HPLC,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000270,OLIGO_0000270,DEBACKER_GALNAC_LIVER_DELIVERY_REVIEW_2020,2prime_F,partial_PS,0.33793,medium_PS,0,2prime_F|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_6,0.951,literature_grounded_generated,GalNAc_ASGPR_liver_delivery_review_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000271,OLIGO_0000271,YAMAGUCHI_SCPBNA2_REDUCED_HEPATOTOX_2025,2prime_MOE,partial_PS,0.32929,low_PS,0,2prime_MOE|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_8,0.97052,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000272,OLIGO_0000272,DEBACKER_GALNAC_LIVER_DELIVERY_REVIEW_2020,LNA,low_or_no_PS,0.03556,low_PS,1,LNA|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_1,0.9259,literature_grounded_generated,GalNAc_ASGPR_liver_delivery_review_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000273,OLIGO_0000273,DUDZICZ_ZILEBESIRAN_HTN_REVIEW_2025,2prime_OMe,low_or_no_PS,0.03677,low_PS,1,2prime_OMe|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_1,0.98206,inferred_from_paper,HPLC+LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000274,OLIGO_0000274,SCHLEGEL_ESCPLUS_SEED_PAIRING_GALNAC_SIRNA_2022,LNA,partial_PS,0.43999,medium_PS,0,LNA|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_11,0.98989,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000275,OLIGO_0000275,HJELMGREN_PS_ASO_DDR_2026,LNA_mixed,high_PS,0.7,high_PS,0,LNA_mixed|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_16,0.99153,literature_grounded_generated,IFN_alpha_disulfidptosis_context_nonreducing_WB_NADPH_Factin_siRNA_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000276,OLIGO_0000276,KUMAGAI_SCPBNA2_PURINE_SYNTHESIS_2025,2prime_F,partial_PS,0.28133,low_PS,0,2prime_F|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_7,0.9676,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000277,OLIGO_0000277,DEBACKER_GALNAC_LIVER_DELIVERY_REVIEW_2020,AmNA,partial_PS,0.11026,low_PS,0,AmNA|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_3,0.97581,literature_grounded_generated,GalNAc_ASGPR_liver_delivery_review_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000278,OLIGO_0000278,BERGEN_DILIMAP_TOXPREDICTOR_DILI_2025,cEt,partial_PS,0.46714,medium_PS,0,cEt|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_10,0.97446,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000279,OLIGO_0000279,KIM_LARP6_HSC_FIBROSIS_DSI_RNA_2026,2prime_MOE,partial_PS,0.10288,low_PS,1,2prime_MOE|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_2,0.96257,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000280,OLIGO_0000280,KIM_MILASEN_CUSTOM_ASO_2019,2prime_MOE,high_PS,1.0,high_PS,0,2prime_MOE|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_21,0.92955,inferred_from_paper,HPLC,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000281,OLIGO_0000281,JANAS_GALNAC_SIRNA_OFFTARGET_RAT_HEPATOTOX_2018,mixed,partial_PS,0.12283,low_PS,0,mixed|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_3,0.9785,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000282,OLIGO_0000282,MA_HSD17B13_ASO_FIBROSIS_MOUSE_2024,mixed,partial_PS,0.18516,low_PS,0,mixed|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_4,0.94836,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000283,OLIGO_0000283,DUDZICZ_ZILEBESIRAN_HTN_REVIEW_2025,mixed,partial_PS,0.37794,medium_PS,1,mixed|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_11,0.99877,inferred_from_paper,HPLC,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000284,OLIGO_0000284,EGLI_MANOHARAN_APPROVED_OLIGO_CHEMISTRY_2023,LNA,partial_PS,0.52787,medium_PS,0,LNA|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_11,0.93772,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000285,OLIGO_0000285,EGLI_MANOHARAN_APPROVED_OLIGO_CHEMISTRY_2023,LNA,high_PS,0.85184,high_PS,1,LNA|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_20,0.97806,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000286,OLIGO_0000286,HUANG_AGT_GALNAC_SIRNA_TOXICOLOGY_2025,2prime_MOE,partial_PS,0.49919,medium_PS,0,2prime_MOE|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_12,0.98149,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000287,OLIGO_0000287,ZHAI_GALNAC_LNP_SIMKK4_LIVER_REGEN_2026,synthetic_siRNA_payload_proxy,low_or_no_PS,0.0,low_PS,1,synthetic_siRNA_payload_proxy|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_0,0.89784,inferred_from_paper,qRT_PCR_flow_CLSM_hemolysis_live_dead_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000288,OLIGO_0000288,CROOKE_RNA_TARGETED_THERAPEUTICS_2018,2prime_OMe,low_or_no_PS,0.03269,low_PS,0,2prime_OMe|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_1,0.97091,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000289,OLIGO_0000289,LIVER_SPHEROID_SCHOLTEN_2026,AmNA,partial_PS,0.22697,low_PS,1,AmNA|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_5,0.999,inferred_from_paper,HPLC,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000290,OLIGO_0000290,RAPIROSIRAN_SANYAL_2025,cEt,low_or_no_PS,0.02225,low_PS,1,cEt|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_1,0.99898,inferred_from_paper,HPLC,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000291,OLIGO_0000291,MEMO_OLIGOTOX_PHASE2_ALIGNMENT,LNA,high_PS,0.706,high_PS,1,LNA|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_10,0.999,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000292,OLIGO_0000292,MA_HSD17B13_ASO_FIBROSIS_MOUSE_2024,LNA,partial_PS,0.57657,medium_PS,0,LNA|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_14,0.94462,literature_grounded_generated,not_reported_generated,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000293,OLIGO_0000293,KIM_NANP_LIPID_LIVER_TARGETING_2026,2prime_MOE,partial_PS,0.12195,low_PS,1,2prime_MOE|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_3,0.93293,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000294,OLIGO_0000294,YAMAGUCHI_SCPBNA2_REDUCED_HEPATOTOX_2025,mixed,partial_PS,0.3443,medium_PS,1,mixed|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_9,0.97003,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000295,OLIGO_0000295,HJELMGREN_PS_ASO_DDR_2026,LNA_mixed,high_PS,0.73242,high_PS,1,LNA_mixed|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_19,0.95256,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000296,OLIGO_0000296,KIM_LARP6_HSC_FIBROSIS_DSI_RNA_2026,2prime_MOE,high_PS,0.67405,high_PS,0,2prime_MOE|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_16,0.94787,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000297,OLIGO_0000297,JANAS_GALNAC_RNAI_NONCLINICAL_SAFETY_2018,2prime_F,high_PS,0.80354,high_PS,0,2prime_F|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_11,0.99013,literature_grounded_generated,rat_monkey_repeat_dose_toxicology_platform_safety_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000298,OLIGO_0000298,GANE_VIR2218_ALNHBV_HBV_RNAI_2023,mixed_ESC_parent,partial_PS,0.17182,low_PS,1,mixed_ESC_parent|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_4,0.91941,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000299,OLIGO_0000299,AGARWAL_GALNAC_SIRNA_OFFTARGET_2025,AmNA,partial_PS,0.49569,medium_PS,0,AmNA|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_10,0.96811,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000300,OLIGO_0000300,ARMISEN_AZD2693_PNPLA3_ASO_MASH_2025,2prime_F,partial_PS,0.43332,medium_PS,0,2prime_F|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_11,0.999,literature_grounded_generated,IFN_alpha_disulfidptosis_context_nonreducing_WB_NADPH_Factin_siRNA_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000301,OLIGO_0000301,BOSCO_INCLISIRAN_FH_REALWORLD_2025,2prime_F,partial_PS,0.50159,medium_PS,1,2prime_F|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_11,0.97529,literature_grounded_generated,real_world_six_month_lipid_PWV_ALT_AST_CPK_monitoring_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000302,OLIGO_0000302,BI_IFNA_DISULFIDPTOSIS_HCC_2026,2prime_MOE,partial_PS,0.4619,medium_PS,0,2prime_MOE|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_9,0.92462,literature_grounded_generated,IFN_alpha_disulfidptosis_context_nonreducing_WB_NADPH_Factin_siRNA_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000303,OLIGO_0000303,HAGEDORN_LNA_HEPATOTOX_RF_2013,LNA,high_PS,0.88992,high_PS,0,LNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_12,0.93584,inferred_from_paper,ion_exchange_HPLC_LC_MS_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000304,OLIGO_0000304,PAN_CD133_MASLD_HCC_SIRNA_2025,2prime_OMe_pyrimidine_modified_siRNA_proxy,partial_PS,0.26945,low_PS,0,2prime_OMe_pyrimidine_modified_siRNA_proxy|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_5,0.92136,inferred_from_paper,organoid_limiting_dilution_assay_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000305,OLIGO_0000305,KEATING_ASO_OBESITY_NAFLD_2022,2prime_MOE,partial_PS,0.52544,medium_PS,0,2prime_MOE|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_11,0.93298,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000306,OLIGO_0000306,RAPIROSIRAN_SANYAL_2025,cEt,partial_PS,0.228,low_PS,1,cEt|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_3,0.959,inferred_from_paper,HPLC,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000307,OLIGO_0000307,WANG_PMEVL_SEV_SMALL_RNA_PCSK9_2026,not_applicable_sEV_payload_context,low_or_no_PS,0.0,low_PS,0,not_applicable_sEV_payload_context|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_0,0.999,literature_grounded_generated,RT_qPCR_NTA_TEM_Western_RNase_protection_IVIS_ALT_AST_H_E_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000308,OLIGO_0000308,YAMAGUCHI_SCPBNA2_REDUCED_HEPATOTOX_2025,2prime_F,high_PS,0.6812,high_PS,0,2prime_F|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_12,0.95355,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000309,OLIGO_0000309,KIM_LARP6_HSC_FIBROSIS_DSI_RNA_2026,AmNA,partial_PS,0.11606,low_PS,0,AmNA|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_2,0.97625,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000310,OLIGO_0000310,JIANG_LNP_CRISPR_HAO1_PH1_2025,unmodified,partial_PS,0.12755,low_PS,0,unmodified|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_3,0.94015,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000311,OLIGO_0000311,HUANG_GALNAC_RBC_EV_LIVER_DISEASE_2025,cholesterol_GalNAc_tethered_oligo_proxy,partial_PS,0.31467,low_PS,1,cholesterol_GalNAc_tethered_oligo_proxy|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_6,0.90335,inferred_from_paper,PANoptosis_WB_TUNEL_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000312,OLIGO_0000312,MEMO_OLIGOTOX_PHASE2_ALIGNMENT,cEt,partial_PS,0.48826,medium_PS,0,cEt|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_9,0.97966,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000313,OLIGO_0000313,ABULHUSN_HSD17B13_PROTECTIVE_VARIANT_2018,LNA,partial_PS,0.39949,medium_PS,1,LNA|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_8,0.999,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000314,OLIGO_0000314,WANG_OGT_SEV_LSEC_MASLD_2026,not_applicable,low_or_no_PS,0.0,low_PS,0,not_applicable,not_applicable,0.82873,inferred_from_paper,NTA_TEM_Western_sEV_marker_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000315,OLIGO_0000315,BOSCO_INCLISIRAN_FH_REALWORLD_2025,2prime_OMe,partial_PS,0.31597,low_PS,0,2prime_OMe|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_8,0.98452,literature_grounded_generated,real_world_six_month_lipid_PWV_ALT_AST_CPK_monitoring_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000316,OLIGO_0000316,LIU_CYP2E1_LNP_APAP_AILI_2025,mixed,partial_PS,0.05655,low_PS,0,mixed|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_1,0.94406,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000317,OLIGO_0000317,OLSON_CHOLANGIOCYTE_CHOLESTASIS_2025,2prime_OMe,partial_PS,0.64347,medium_PS,1,2prime_OMe|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_16,0.97588,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000318,OLIGO_0000318,BI_IFNA_DISULFIDPTOSIS_HCC_2026,cEt,low_or_no_PS,0.02388,low_PS,0,cEt|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_1,0.96661,literature_grounded_generated,IFN_alpha_disulfidptosis_context_nonreducing_WB_NADPH_Factin_siRNA_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000319,OLIGO_0000319,ZHAI_GALNAC_LNP_SIMKK4_LIVER_REGEN_2026,synthetic_siRNA_payload_proxy,low_or_no_PS,0.0,low_PS,1,synthetic_siRNA_payload_proxy|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_0,0.98354,inferred_from_paper,MicroCT_H_E_Ki67_TUNEL_biochemistry_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000320,OLIGO_0000320,LIU_CYP2E1_LNP_APAP_AILI_2025,cEt,partial_PS,0.42824,medium_PS,1,cEt|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_11,0.96488,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000321,OLIGO_0000321,RAPIROSIRAN_SANYAL_2025,unmodified,partial_PS,0.47628,medium_PS,1,unmodified|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_10,0.95505,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000322,OLIGO_0000322,RO7239958_GERETTI_2025,2prime_F,partial_PS,0.1088,low_PS,0,2prime_F|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_3,0.97994,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000323,OLIGO_0000323,BUREL_GAPMER_RNASEH1_LONG_PREMRNA_HEPATOTOX_2016,mixed,partial_PS,0.15339,low_PS,1,mixed|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_3,0.94182,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000324,OLIGO_0000324,MA_HSD17B13_ASO_FIBROSIS_MOUSE_2024,2prime_MOE,high_PS,0.80004,high_PS,0,2prime_MOE|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_14,0.95713,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000325,OLIGO_0000325,RAPIROSIRAN_SANYAL_2025,2prime_OMe,partial_PS,0.24624,low_PS,1,2prime_OMe|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_6,0.96099,inferred_from_paper,not_reported_generated,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000326,OLIGO_0000326,PRAKASH_APOC3_LONG_ACTING_GALNAC_SIRNA_2025,mixed,partial_PS,0.45386,medium_PS,1,mixed|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_13,0.94921,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000327,OLIGO_0000327,BERGEN_DILIMAP_TOXPREDICTOR_DILI_2025,2prime_OMe,partial_PS,0.05626,low_PS,0,2prime_OMe|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_1,0.9735,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000328,OLIGO_0000328,ZHAI_GALNAC_LNP_SIMKK4_LIVER_REGEN_2026,synthetic_siRNA_payload_proxy,low_or_no_PS,0.0,low_PS,1,synthetic_siRNA_payload_proxy|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_0,0.87808,inferred_from_paper,MicroCT_H_E_Ki67_TUNEL_biochemistry_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000329,OLIGO_0000329,RAPIROSIRAN_SANYAL_2025,mixed,partial_PS,0.0851,low_PS,1,mixed|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_2,0.93004,inferred_from_paper,HPLC,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000330,OLIGO_0000330,ARMISEN_AZD2693_PNPLA3_ASO_MASH_2025,2prime_MOE,partial_PS,0.05708,low_PS,0,2prime_MOE|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_1,0.95712,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000331,OLIGO_0000331,OLSON_CHOLANGIOCYTE_CHOLESTASIS_2025,2prime_MOE,partial_PS,0.5666,medium_PS,0,2prime_MOE|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_14,0.95598,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000332,OLIGO_0000332,WANG_OGT_SEV_LSEC_MASLD_2026,not_applicable,low_or_no_PS,0.0,low_PS,0,not_applicable,not_applicable,0.79671,inferred_from_paper,SEM_LSEC_fenestration_Ang2_ELISA_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000333,OLIGO_0000333,HAGEDORN_LNA_HEPATOTOX_RF_2013,LNA,high_PS,0.90238,high_PS,0,LNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_13,0.94496,inferred_from_paper,ion_exchange_HPLC_LC_MS_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000334,OLIGO_0000334,BERGEN_DILIMAP_TOXPREDICTOR_DILI_2025,unmodified,partial_PS,0.18537,low_PS,0,unmodified|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_5,0.9453,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000335,OLIGO_0000335,BOSCO_INCLISIRAN_FH_REALWORLD_2025,cEt,partial_PS,0.07617,low_PS,1,cEt|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_1,0.95293,literature_grounded_generated,real_world_six_month_lipid_PWV_ALT_AST_CPK_monitoring_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000336,OLIGO_0000336,LIU_CYP2E1_LNP_APAP_AILI_2025,AmNA,partial_PS,0.55398,medium_PS,0,AmNA|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_9,0.96574,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000337,OLIGO_0000337,YAMAGUCHI_SCPBNA2_REDUCED_HEPATOTOX_2025,LNA,partial_PS,0.3377,medium_PS,0,LNA|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_6,0.999,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000338,OLIGO_0000338,KEATING_ASO_OBESITY_NAFLD_2022,2prime_MOE,low_or_no_PS,0.00193,low_PS,0,2prime_MOE|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_0,0.97731,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000339,OLIGO_0000339,RAPIROSIRAN_SANYAL_2025,2prime_F,partial_PS,0.18373,low_PS,1,2prime_F|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_4,0.94381,inferred_from_paper,HPLC,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000340,OLIGO_0000340,ARMISEN_AZD2693_PNPLA3_ASO_MASH_2025,2prime_MOE,high_PS,0.80271,high_PS,0,2prime_MOE|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_23,0.97691,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000341,OLIGO_0000341,WANG_OGT_SEV_LSEC_MASLD_2026,not_applicable,low_or_no_PS,0.0,low_PS,0,not_applicable,not_applicable,0.83689,inferred_from_paper,ALT_AST_TG_inflammation_histology_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000342,OLIGO_0000342,MEKONNEN_MYC_ASIRNA_DCA_TNBC_2025,AmNA,high_PS,0.74461,high_PS,0,AmNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_14,0.95768,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000343,OLIGO_0000343,BUREL_GAPMER_RNASEH1_LONG_PREMRNA_HEPATOTOX_2016,2prime_MOE,partial_PS,0.58096,medium_PS,0,2prime_MOE|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_10,0.95931,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000344,OLIGO_0000344,OOSTVEEN_ANGPTL3_LIVER_SAFETY_2023,2prime_MOE,partial_PS,0.1591,low_PS,1,2prime_MOE|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_4,0.94401,inferred_from_paper,HPLC,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000345,OLIGO_0000345,BOSCO_INCLISIRAN_FH_REALWORLD_2025,mixed,partial_PS,0.1037,low_PS,0,mixed|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_2,0.9967,literature_grounded_generated,real_world_six_month_lipid_PWV_ALT_AST_CPK_monitoring_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000346,OLIGO_0000346,SOUSA_HDO_MULTIFUNCTIONAL_HELA_2022,LNA,high_PS,0.86051,high_PS,1,LNA|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_22,0.97191,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000347,OLIGO_0000347,KEATING_ASO_OBESITY_NAFLD_2022,mixed,partial_PS,0.62368,medium_PS,0,mixed|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_16,0.94431,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000348,OLIGO_0000348,EGLI_MANOHARAN_APPROVED_OLIGO_CHEMISTRY_2023,2prime_F,partial_PS,0.24071,low_PS,0,2prime_F|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_6,0.97158,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000349,OLIGO_0000349,ABULHUSN_HSD17B13_PROTECTIVE_VARIANT_2018,mixed,high_PS,0.95131,high_PS,1,mixed|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_17,0.91728,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000350,OLIGO_0000350,PAN_CD133_MASLD_HCC_SIRNA_2025,2prime_OMe,partial_PS,0.11699,low_PS,0,2prime_OMe|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_3,0.91118,inferred_from_paper,VNP_siRNA_sorafenib_lenvatinib_response_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000351,OLIGO_0000351,HJELMGREN_PS_ASO_DDR_2026,2prime_MOE,high_PS,0.7,high_PS,0,2prime_MOE|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_19,0.94082,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000352,OLIGO_0000352,BI_IFNA_DISULFIDPTOSIS_HCC_2026,cEt,partial_PS,0.15983,low_PS,1,cEt|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_4,0.93414,literature_grounded_generated,IFN_alpha_disulfidptosis_context_nonreducing_WB_NADPH_Factin_siRNA_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000353,OLIGO_0000353,DU_MALAT1_HBV_HCC_ASO_2025,ASO_proxy,partial_PS,0.66491,medium_PS,0,ASO_proxy|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_11,0.88963,inferred_from_paper,qRT_PCR_FISH_MeRIP_RIP_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000354,OLIGO_0000354,LIU_CYP2E1_LNP_APAP_AILI_2025,LNA,high_PS,0.7957,high_PS,1,LNA|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_18,0.999,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000355,OLIGO_0000355,PRAKASH_APOC3_LONG_ACTING_GALNAC_SIRNA_2025,LNA,high_PS,0.85749,high_PS,1,LNA|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_21,0.91961,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000356,OLIGO_0000356,ARMISEN_AZD2693_PNPLA3_ASO_MASH_2025,AmNA,partial_PS,0.16155,low_PS,0,AmNA|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_4,0.96496,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000357,OLIGO_0000357,HUANG_AGT_GALNAC_SIRNA_TOXICOLOGY_2025,LNA,partial_PS,0.40612,medium_PS,0,LNA|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_10,0.999,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000358,OLIGO_0000358,LAN_SIRUBICON_ROS_GALNAC_MASH_2025,mixed_2prime_F_2prime_OMe_siRNA,partial_PS,0.0556,low_PS,1,mixed_2prime_F_2prime_OMe_siRNA|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_1,0.9688,inferred_from_paper,nanoparticle_DLS_zeta_biodistribution_Rubicon_knockdown_ALT_AST_generated_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000359,OLIGO_0000359,ANDERSSON_PRECLINICAL_OLIGO_SAFETY_2022,mixed,partial_PS,0.19372,low_PS,0,mixed|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_4,0.9732,literature_grounded_generated,preclinical_safety_screening_cascade_ALT_AST_kidney_complement_platelet_offtarget_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000360,OLIGO_0000360,AGARWAL_GALNAC_SIRNA_OFFTARGET_2025,AmNA,partial_PS,0.20432,low_PS,1,AmNA|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_4,0.999,literature_grounded_generated,not_reported_generated,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000361,OLIGO_0000361,RAPIROSIRAN_SANYAL_2025,cEt,partial_PS,0.23504,low_PS,1,cEt|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_5,0.93664,inferred_from_paper,HPLC+LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000362,OLIGO_0000362,HAUPTMANN_SIRNA_BULGES_GALNAC_2022,2OMe_2F_alternating,partial_PS,0.10584,low_PS,0,2OMe_2F_alternating|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_2,0.93719,inferred_from_paper,qRT_PCR_ELISA_reporter_melting_LCMS_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000363,OLIGO_0000363,LIU_CYP2E1_LNP_APAP_AILI_2025,mixed,partial_PS,0.53004,medium_PS,1,mixed|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_13,0.92423,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000364,OLIGO_0000364,AGARWAL_GALNAC_SIRNA_OFFTARGET_2025,LNA,high_PS,0.89367,high_PS,1,LNA|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_19,0.94187,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000365,OLIGO_0000365,BI_IFNA_DISULFIDPTOSIS_HCC_2026,2prime_OMe,partial_PS,0.18935,low_PS,0,2prime_OMe|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_5,0.999,literature_grounded_generated,IFN_alpha_disulfidptosis_context_nonreducing_WB_NADPH_Factin_siRNA_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000366,OLIGO_0000366,PARK_ERBB2_APTAMER_PET_PK_2023,2prime_OMe,partial_PS,0.47787,medium_PS,1,2prime_OMe|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_10,0.99219,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000367,OLIGO_0000367,OLSON_CHOLANGIOCYTE_CHOLESTASIS_2025,LNA,partial_PS,0.2526,low_PS,0,LNA|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_6,0.95375,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000368,OLIGO_0000368,ABULHUSN_HSD17B13_PROTECTIVE_VARIANT_2018,mixed,partial_PS,0.05408,low_PS,0,mixed|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_1,0.999,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000369,OLIGO_0000369,ARMISEN_AZD2693_PNPLA3_ASO_MASH_2025,2prime_OMe,high_PS,0.78923,high_PS,0,2prime_OMe|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_16,0.9772,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000370,OLIGO_0000370,TERADA_BROTHERS_ASO_PNA_TOEHOLD_2023,AmNA,partial_PS,0.25413,low_PS,1,AmNA|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_5,0.98066,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000371,OLIGO_0000371,GANE_VIR2218_ALNHBV_HBV_RNAI_2023,mixed_ESCplus_GNA_seed,high_PS,0.96332,high_PS,1,mixed_ESCplus_GNA_seed|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_13,0.97269,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000372,OLIGO_0000372,ABULHUSN_HSD17B13_PROTECTIVE_VARIANT_2018,2prime_MOE,partial_PS,0.08984,low_PS,0,2prime_MOE|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_2,0.93958,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000373,OLIGO_0000373,SUBRAMANIAN_RNAI_RHEOSTAT_AAV_TRANSGENE_2023,LNA,high_PS,0.95739,high_PS,1,LNA|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_18,0.95584,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000374,OLIGO_0000374,BOSCO_INCLISIRAN_FH_REALWORLD_2025,LNA,partial_PS,0.60597,medium_PS,1,LNA|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_17,0.98286,literature_grounded_generated,real_world_six_month_lipid_PWV_ALT_AST_CPK_monitoring_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000375,OLIGO_0000375,KANDA_PCDHA11_AMNA_ASO_2024,AmNA,high_PS,1.0,high_PS,0,AmNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_19,0.98311,inferred_from_paper,AmNA_ASO_synthesis_HPLC_LCMS_qPCR_microarray_toxicology_generated_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000376,OLIGO_0000376,ABULHUSN_HSD17B13_PROTECTIVE_VARIANT_2018,mixed,low_or_no_PS,0.0398,low_PS,0,mixed|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_1,0.9401,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000377,OLIGO_0000377,RO7239958_GERETTI_2025,AmNA,partial_PS,0.37404,medium_PS,1,AmNA|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_7,0.96449,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000378,OLIGO_0000378,KANDA_PCDHA11_AMNA_ASO_2024,AmNA,high_PS,1.0,high_PS,0,AmNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_17,0.97719,inferred_from_paper,AmNA_ASO_synthesis_HPLC_LCMS_qPCR_microarray_toxicology_generated_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000379,OLIGO_0000379,MA_HSD17B13_ASO_FIBROSIS_MOUSE_2024,LNA,partial_PS,0.3015,low_PS,1,LNA|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_6,0.95436,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000380,OLIGO_0000380,JANAS_GALNAC_RNAI_NONCLINICAL_SAFETY_2018,LNA,high_PS,0.79223,high_PS,0,LNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_13,0.96539,literature_grounded_generated,rat_monkey_repeat_dose_toxicology_platform_safety_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000381,OLIGO_0000381,HAGEDORN_LNA_HEPATOTOX_RF_2013,LNA,high_PS,0.93283,high_PS,0,LNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_13,0.98579,inferred_from_paper,ion_exchange_HPLC_LC_MS_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000382,OLIGO_0000382,KANDA_PCDHA11_AMNA_ASO_2024,AmNA,high_PS,1.0,high_PS,0,AmNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_15,0.99576,inferred_from_paper,AmNA_ASO_synthesis_HPLC_LCMS_qPCR_microarray_toxicology_generated_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000383,OLIGO_0000383,ABULHUSN_HSD17B13_PROTECTIVE_VARIANT_2018,2prime_OMe,partial_PS,0.11672,low_PS,1,2prime_OMe|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_3,0.98721,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000384,OLIGO_0000384,ENGELBEEN_ALK4_MUSCLE_SIRNA_2023,mixed,partial_PS,0.25929,low_PS,0,mixed|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_4,0.96371,inferred_from_paper,not_reported_generated,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000385,OLIGO_0000385,PAN_CD133_MASLD_HCC_SIRNA_2025,2prime_OMe_pyrimidine_modified_siRNA_proxy,partial_PS,0.41925,medium_PS,0,2prime_OMe_pyrimidine_modified_siRNA_proxy|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_8,0.91078,inferred_from_paper,VNP_siRNA_sorafenib_lenvatinib_response_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000386,OLIGO_0000386,HJELMGREN_PS_ASO_DDR_2026,RNA_PS,high_PS,0.7,high_PS,1,RNA_PS|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_15,0.99186,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000387,OLIGO_0000387,BERGEN_DILIMAP_TOXPREDICTOR_DILI_2025,unmodified,partial_PS,0.17566,low_PS,0,unmodified|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_4,0.96572,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000388,OLIGO_0000388,KIM_NANP_LIPID_LIVER_TARGETING_2026,AmNA,partial_PS,0.50383,medium_PS,1,AmNA|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_12,0.94527,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000389,OLIGO_0000389,MEKONNEN_MYC_ASIRNA_DCA_TNBC_2025,LNA,high_PS,0.88551,high_PS,1,LNA|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_19,0.94198,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000390,OLIGO_0000390,DU_MALAT1_HBV_HCC_ASO_2025,ASO_proxy,partial_PS,0.56308,medium_PS,0,ASO_proxy|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_11,0.88153,inferred_from_paper,RNA_pulldown_luciferase_RNA_decay_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000391,OLIGO_0000391,JANAS_GALNAC_RNAI_NONCLINICAL_SAFETY_2018,2prime_MOE,partial_PS,0.23933,low_PS,1,2prime_MOE|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_6,0.98935,literature_grounded_generated,rat_monkey_repeat_dose_toxicology_platform_safety_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000392,OLIGO_0000392,KARTOUN_MELD_PLUS_CIRRHOSIS_2017,not_applicable_clinical_risk_score_context,low_or_no_PS,0.0,low_PS,0,not_applicable,not_applicable,0.97638,inferred_from_paper,EMR_structured_variables_LASSO_logistic_regression_AUROC_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000393,OLIGO_0000393,LAN_SIRUBICON_ROS_GALNAC_MASH_2025,mixed_2prime_F_2prime_OMe_siRNA,low_or_no_PS,0.04,low_PS,1,mixed_2prime_F_2prime_OMe_siRNA|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_1,0.999,inferred_from_paper,nanoparticle_DLS_zeta_biodistribution_Rubicon_knockdown_ALT_AST_generated_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000394,OLIGO_0000394,RAPIROSIRAN_SANYAL_2025,unmodified,partial_PS,0.62604,medium_PS,0,unmodified|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_14,0.999,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000395,OLIGO_0000395,WAN_PUM1_EXOSOMES_MASLD_HSC_FIBROSIS_2025,unmodified,partial_PS,0.28641,low_PS,0,unmodified|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_7,0.96155,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000396,OLIGO_0000396,MEKONNEN_MYC_ASIRNA_DCA_TNBC_2025,2prime_F,partial_PS,0.62231,medium_PS,0,2prime_F|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_12,0.92266,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000397,OLIGO_0000397,JANAS_GALNAC_RNAI_NONCLINICAL_SAFETY_2018,2prime_OMe,partial_PS,0.47297,medium_PS,0,2prime_OMe|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_11,0.95319,literature_grounded_generated,rat_monkey_repeat_dose_toxicology_platform_safety_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000398,OLIGO_0000398,KANDA_PCDHA11_AMNA_ASO_2024,AmNA,high_PS,1.0,high_PS,0,AmNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_17,0.9614,inferred_from_paper,AmNA_ASO_synthesis_HPLC_LCMS_qPCR_microarray_toxicology_generated_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000399,OLIGO_0000399,LIU_CYP2E1_LNP_APAP_AILI_2025,2prime_OMe,high_PS,0.92841,high_PS,0,2prime_OMe|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_23,0.999,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000400,OLIGO_0000400,TERADA_BROTHERS_ASO_PNA_TOEHOLD_2023,mixed,partial_PS,0.1864,low_PS,1,mixed|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_4,0.9403,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000401,OLIGO_0000401,DHARA_LNA_PHOSPHOTHIOTRIESTER_SSO_CLICK_2025,mixed,partial_PS,0.35863,medium_PS,1,mixed|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_7,0.999,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000402,OLIGO_0000402,KANDA_PCDHA11_AMNA_ASO_2024,AmNA,high_PS,1.0,high_PS,0,AmNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_19,0.98193,inferred_from_paper,AmNA_ASO_synthesis_HPLC_LCMS_qPCR_microarray_toxicology_generated_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000403,OLIGO_0000403,SCHLEGEL_ESCPLUS_SEED_PAIRING_GALNAC_SIRNA_2022,unmodified,partial_PS,0.14905,low_PS,1,unmodified|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_3,0.95291,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000404,OLIGO_0000404,QU_CPG_ODN_APAP_TLR9_IRG1_2025,2prime_MOE,partial_PS,0.26856,low_PS,0,2prime_MOE|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_6,0.999,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000405,OLIGO_0000405,RO7239958_GERETTI_2025,2prime_OMe,partial_PS,0.27796,low_PS,0,2prime_OMe|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_6,0.99063,literature_grounded_generated,IFN_alpha_disulfidptosis_context_nonreducing_WB_NADPH_Factin_siRNA_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000406,OLIGO_0000406,OLSON_CHOLANGIOCYTE_CHOLESTASIS_2025,2prime_MOE,partial_PS,0.21028,low_PS,0,2prime_MOE|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_5,0.93621,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000407,OLIGO_0000407,DEBACKER_GALNAC_LIVER_DELIVERY_REVIEW_2020,LNA,partial_PS,0.17965,low_PS,0,LNA|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_4,0.91554,literature_grounded_generated,GalNAc_ASGPR_liver_delivery_review_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000408,OLIGO_0000408,BI_IFNA_DISULFIDPTOSIS_HCC_2026,LNA,high_PS,0.75816,high_PS,1,LNA|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_20,0.98945,literature_grounded_generated,IFN_alpha_disulfidptosis_context_nonreducing_WB_NADPH_Factin_siRNA_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000409,OLIGO_0000409,JANAS_GALNAC_SIRNA_OFFTARGET_RAT_HEPATOTOX_2018,AmNA,partial_PS,0.26394,low_PS,0,AmNA|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_5,0.95591,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000410,OLIGO_0000410,AGARWAL_GALNAC_SIRNA_OFFTARGET_2025,unmodified,partial_PS,0.20518,low_PS,0,unmodified|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_4,0.93823,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000411,OLIGO_0000411,JANAS_GALNAC_RNAI_NONCLINICAL_SAFETY_2018,mixed,partial_PS,0.21443,low_PS,0,mixed|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_5,0.98595,literature_grounded_generated,rat_monkey_repeat_dose_toxicology_platform_safety_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000412,OLIGO_0000412,LU_GT_MULTI_SIRNA_HCC_2025,unmodified,partial_PS,0.56663,medium_PS,0,unmodified|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_15,0.97852,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000413,OLIGO_0000413,LIVER_SPHEROID_SCHOLTEN_2026,2prime_F,partial_PS,0.54447,medium_PS,1,2prime_F|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_14,0.999,inferred_from_paper,HPLC+LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000414,OLIGO_0000414,HJELMGREN_PS_ASO_DDR_2026,LNA_mixed,high_PS,0.7,high_PS,1,LNA_mixed|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_15,0.91576,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000415,OLIGO_0000415,RO7239958_GERETTI_2025,LNA,high_PS,0.96566,high_PS,1,LNA|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_22,0.97362,inferred_from_paper,HPLC,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000416,OLIGO_0000416,BERGEN_DILIMAP_TOXPREDICTOR_DILI_2025,2prime_MOE,partial_PS,0.29037,low_PS,0,2prime_MOE|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_7,0.97383,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000417,OLIGO_0000417,KANDA_PCDHA11_AMNA_ASO_2024,AmNA,high_PS,1.0,high_PS,0,AmNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_17,0.97243,inferred_from_paper,AmNA_ASO_synthesis_HPLC_LCMS_qPCR_microarray_toxicology_generated_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000418,OLIGO_0000418,MA_HSD17B13_ASO_FIBROSIS_MOUSE_2024,2prime_MOE,partial_PS,0.40921,medium_PS,1,2prime_MOE|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_11,0.94841,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000419,OLIGO_0000419,RO7239958_GERETTI_2025,LNA,high_PS,0.9144,high_PS,1,LNA|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_19,0.95491,inferred_from_paper,LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000420,OLIGO_0000420,RO7239958_GERETTI_2025,LNA,partial_PS,0.54865,medium_PS,1,LNA|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_12,0.96909,inferred_from_paper,LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000421,OLIGO_0000421,ARMISEN_AZD2693_PNPLA3_ASO_MASH_2025,2prime_OMe,partial_PS,0.31763,low_PS,0,2prime_OMe|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_8,0.96027,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000422,OLIGO_0000422,LIVER_SPHEROID_SCHOLTEN_2026,2prime_OMe,high_PS,0.78095,high_PS,1,2prime_OMe|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_11,0.99613,inferred_from_paper,LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000423,OLIGO_0000423,LI_FXR_JNK_G0S2_TRIPTOLIDE_HEPATOTOXICITY_2025,mixed,high_PS,0.78902,high_PS,0,mixed|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_19,0.955,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000424,OLIGO_0000424,DEBACKER_GALNAC_LIVER_DELIVERY_REVIEW_2020,2prime_F,high_PS,0.85581,high_PS,0,2prime_F|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_22,0.96161,literature_grounded_generated,GalNAc_ASGPR_liver_delivery_review_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000425,OLIGO_0000425,MEKONNEN_MYC_ASIRNA_DCA_TNBC_2025,2prime_OMe,partial_PS,0.18417,low_PS,0,2prime_OMe|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_4,0.9405,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000426,OLIGO_0000426,UMEZU_ORAL_MIR29A_LIVER_FIBROSIS_NA_2025,2prime_F,partial_PS,0.08198,low_PS,0,2prime_F|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_2,0.93539,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000427,OLIGO_0000427,DEBACKER_GALNAC_LIVER_DELIVERY_REVIEW_2020,cEt,partial_PS,0.57288,medium_PS,0,cEt|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_11,0.999,literature_grounded_generated,GalNAc_ASGPR_liver_delivery_review_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000428,OLIGO_0000428,JANAS_GALNAC_SIRNA_OFFTARGET_RAT_HEPATOTOX_2018,cEt,high_PS,0.69913,high_PS,1,cEt|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_13,0.96713,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000429,OLIGO_0000429,AGARWAL_GALNAC_SIRNA_OFFTARGET_2025,2prime_OMe,partial_PS,0.353,medium_PS,1,2prime_OMe|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_8,0.98402,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000430,OLIGO_0000430,MEMO_OLIGOTOX_PHASE2_ALIGNMENT,2prime_MOE,partial_PS,0.15759,low_PS,0,2prime_MOE|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_3,0.96986,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000431,OLIGO_0000431,AGARWAL_GALNAC_SIRNA_OFFTARGET_2025,2prime_MOE,partial_PS,0.32711,low_PS,0,2prime_MOE|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_6,0.95945,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000432,OLIGO_0000432,CROOKE_RNA_TARGETED_THERAPEUTICS_2018,mixed,partial_PS,0.34447,medium_PS,0,mixed|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_8,0.97226,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000433,OLIGO_0000433,LI_FXR_JNK_G0S2_TRIPTOLIDE_HEPATOTOXICITY_2025,2prime_MOE,partial_PS,0.28972,low_PS,0,2prime_MOE|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_5,0.91993,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000434,OLIGO_0000434,SUN_HCC_RNA_NANOPARTICLE_MULTITARGET_2026,LNA,high_PS,0.7283,high_PS,0,LNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_17,0.96982,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000435,OLIGO_0000435,AGARWAL_GALNAC_SIRNA_OFFTARGET_2025,LNA,partial_PS,0.35848,medium_PS,0,LNA|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_8,0.9863,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000436,OLIGO_0000436,RO7239958_GERETTI_2025,LNA,high_PS,0.91021,high_PS,1,LNA|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_15,0.99032,inferred_from_paper,HPLC+LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000437,OLIGO_0000437,CHEN_OVARIAN_MTTP_APOB_MIPOMERSEN_2025,2prime_OMe,partial_PS,0.4842,medium_PS,0,2prime_OMe|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_8,0.97912,inferred_from_paper,LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000438,OLIGO_0000438,JANAS_GALNAC_SIRNA_OFFTARGET_RAT_HEPATOTOX_2018,mixed,partial_PS,0.63094,medium_PS,1,mixed|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_13,0.999,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000439,OLIGO_0000439,LIVER_SPHEROID_SCHOLTEN_2026,LNA,high_PS,0.69052,high_PS,1,LNA|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_16,0.97013,inferred_from_paper,HPLC,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000440,OLIGO_0000440,AGARWAL_GALNAC_SIRNA_OFFTARGET_2025,2prime_OMe,partial_PS,0.24349,low_PS,1,2prime_OMe|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_6,0.96016,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000441,OLIGO_0000441,YAMAGUCHI_SCPBNA2_REDUCED_HEPATOTOX_2025,AmNA,partial_PS,0.27702,low_PS,0,AmNA|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_6,0.999,literature_grounded_generated,not_reported_generated,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000442,OLIGO_0000442,RAPIROSIRAN_SANYAL_2025,2prime_F,partial_PS,0.11098,low_PS,1,2prime_F|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_2,0.999,inferred_from_paper,HPLC,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000443,OLIGO_0000443,ANDERSSON_PRECLINICAL_OLIGO_SAFETY_2022,unmodified,partial_PS,0.1648,low_PS,0,unmodified|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_3,0.97427,literature_grounded_generated,preclinical_safety_screening_cascade_ALT_AST_kidney_complement_platelet_offtarget_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000444,OLIGO_0000444,KIM_LARP6_HSC_FIBROSIS_DSI_RNA_2026,cEt,partial_PS,0.22,low_PS,0,cEt|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_4,0.92459,literature_grounded_generated,IFN_alpha_disulfidptosis_context_nonreducing_WB_NADPH_Factin_siRNA_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000445,OLIGO_0000445,SCHLEGEL_ESCPLUS_SEED_PAIRING_GALNAC_SIRNA_2022,mixed,partial_PS,0.55189,medium_PS,1,mixed|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_14,0.93433,literature_grounded_generated,not_reported_generated,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000446,OLIGO_0000446,JANAS_GALNAC_RNAI_NONCLINICAL_SAFETY_2018,unmodified,partial_PS,0.58217,medium_PS,0,unmodified|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_11,0.93855,literature_grounded_generated,rat_monkey_repeat_dose_toxicology_platform_safety_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000447,OLIGO_0000447,LIU_CYP2E1_LNP_APAP_AILI_2025,mixed,low_or_no_PS,0.02519,low_PS,0,mixed|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_1,0.94531,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000448,OLIGO_0000448,JANAS_GALNAC_SIRNA_OFFTARGET_RAT_HEPATOTOX_2018,LNA,partial_PS,0.16123,low_PS,0,LNA|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_4,0.99226,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000449,OLIGO_0000449,KIM_NANP_LIPID_LIVER_TARGETING_2026,AmNA,high_PS,0.70649,high_PS,0,AmNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_14,0.97792,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000450,OLIGO_0000450,RAPIROSIRAN_SANYAL_2025,2prime_OMe,partial_PS,0.23082,low_PS,1,2prime_OMe|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_4,0.999,inferred_from_paper,HPLC,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000451,OLIGO_0000451,BERGEN_DILIMAP_TOXPREDICTOR_DILI_2025,unmodified,low_or_no_PS,0.04798,low_PS,1,unmodified|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_1,0.92316,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000452,OLIGO_0000452,ARMISEN_AZD2693_PNPLA3_ASO_MASH_2025,LNA,high_PS,0.88903,high_PS,0,LNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_14,0.92613,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000453,OLIGO_0000453,QU_CPG_ODN_APAP_TLR9_IRG1_2025,AmNA,low_or_no_PS,0.03346,low_PS,0,AmNA|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_1,0.97382,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000454,OLIGO_0000454,TERADA_BROTHERS_ASO_PNA_TOEHOLD_2023,unmodified,high_PS,0.75699,high_PS,0,unmodified|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_14,0.93758,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000455,OLIGO_0000455,PARK_ERBB2_APTAMER_PET_PK_2023,2prime_MOE,partial_PS,0.12789,low_PS,1,2prime_MOE|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_3,0.98654,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000456,OLIGO_0000456,ZHAI_GALNAC_LNP_SIMKK4_LIVER_REGEN_2026,synthetic_siRNA_payload_proxy,low_or_no_PS,0.0,low_PS,1,synthetic_siRNA_payload_proxy|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_0,0.87399,inferred_from_paper,MTT_colony_Ki67_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000457,OLIGO_0000457,HUANG_AGT_GALNAC_SIRNA_TOXICOLOGY_2025,2prime_F,partial_PS,0.45451,medium_PS,0,2prime_F|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_10,0.98308,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000458,OLIGO_0000458,WANG_PMEVL_SEV_SMALL_RNA_PCSK9_2026,not_applicable_sEV_payload_context,low_or_no_PS,0.0,low_PS,0,not_applicable_sEV_payload_context|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_0,0.999,literature_grounded_generated,RT_qPCR_NTA_TEM_Western_RNase_protection_IVIS_ALT_AST_H_E_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000459,OLIGO_0000459,WANG_PMEVL_SEV_SMALL_RNA_PCSK9_2026,not_applicable_sEV_payload_context,low_or_no_PS,0.0,low_PS,0,not_applicable_sEV_payload_context|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_0,0.94763,literature_grounded_generated,RT_qPCR_NTA_TEM_Western_RNase_protection_IVIS_ALT_AST_H_E_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000460,OLIGO_0000460,ALSHAER_FDA_TIDES_HARVEST_2025,2prime_MOE,low_or_no_PS,0.03093,low_PS,1,2prime_MOE|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_1,0.999,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000461,OLIGO_0000461,HJELMGREN_PS_ASO_DDR_2026,LNA_mixed,high_PS,0.7,high_PS,1,LNA_mixed|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_10,0.93554,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000462,OLIGO_0000462,JANAS_GALNAC_SIRNA_OFFTARGET_RAT_HEPATOTOX_2018,LNA,partial_PS,0.55113,medium_PS,1,LNA|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_10,0.98814,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000463,OLIGO_0000463,LIVER_SPHEROID_SCHOLTEN_2026,unmodified,partial_PS,0.1195,low_PS,0,unmodified|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_3,0.9879,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000464,OLIGO_0000464,RAPIROSIRAN_SANYAL_2025,LNA,partial_PS,0.13867,low_PS,1,LNA|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_3,0.97415,inferred_from_paper,not_reported_generated,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000465,OLIGO_0000465,EGLI_MANOHARAN_APPROVED_OLIGO_CHEMISTRY_2023,LNA,high_PS,0.88553,high_PS,1,LNA|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_14,0.96272,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000466,OLIGO_0000466,SUBRAMANIAN_RNAI_RHEOSTAT_AAV_TRANSGENE_2023,LNA,partial_PS,0.22803,low_PS,0,LNA|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_5,0.9988,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000467,OLIGO_0000467,WANG_OGT_SEV_LSEC_MASLD_2026,not_applicable,low_or_no_PS,0.0,low_PS,0,not_applicable,not_applicable,0.69211,inferred_from_paper,NTA_TEM_Western_sEV_marker_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000468,OLIGO_0000468,RAPIROSIRAN_SANYAL_2025,unmodified,low_or_no_PS,0.04373,low_PS,1,unmodified|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_1,0.93658,inferred_from_paper,LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000469,OLIGO_0000469,RAPIROSIRAN_SANYAL_2025,mixed,partial_PS,0.21196,low_PS,1,mixed|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_6,0.98459,inferred_from_paper,HPLC+LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000470,OLIGO_0000470,WANG_OGT_SEV_LSEC_MASLD_2026,not_applicable,low_or_no_PS,0.0,low_PS,0,not_applicable,not_applicable,0.92562,inferred_from_paper,SEM_LSEC_fenestration_Ang2_ELISA_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000471,OLIGO_0000471,PNPLA3_ROMEO_VALENTI_2025,LNA,high_PS,0.8742,high_PS,1,LNA|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_17,0.98804,inferred_from_paper,HPLC,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000472,OLIGO_0000472,KIM_GALNAC_SIRNA_LCMS_DPPT_2025,LNA,high_PS,0.80448,high_PS,1,LNA|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_17,0.97362,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000473,OLIGO_0000473,JANAS_GALNAC_SIRNA_OFFTARGET_RAT_HEPATOTOX_2018,LNA,partial_PS,0.05013,low_PS,0,LNA|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_1,0.93862,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000474,OLIGO_0000474,KANDA_PCDHA11_AMNA_ASO_2024,AmNA,high_PS,1.0,high_PS,0,AmNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_17,0.99859,inferred_from_paper,AmNA_ASO_synthesis_HPLC_LCMS_qPCR_microarray_toxicology_generated_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000475,OLIGO_0000475,HUANG_AGT_GALNAC_SIRNA_TOXICOLOGY_2025,mixed,high_PS,0.96911,high_PS,1,mixed|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_22,0.9235,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000476,OLIGO_0000476,TERADA_BROTHERS_ASO_PNA_TOEHOLD_2023,2prime_F,partial_PS,0.23436,low_PS,1,2prime_F|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_5,0.97401,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000477,OLIGO_0000477,HAUPTMANN_SIRNA_BULGES_GALNAC_2022,2OMe_2F_alternating,partial_PS,0.15854,low_PS,0,2OMe_2F_alternating|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_3,0.91983,inferred_from_paper,qRT_PCR_ELISA_reporter_melting_LCMS_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000478,OLIGO_0000478,WAN_PUM1_EXOSOMES_MASLD_HSC_FIBROSIS_2025,2prime_F,low_or_no_PS,0.03426,low_PS,0,2prime_F|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_1,0.97684,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000479,OLIGO_0000479,KIM_LARP6_HSC_FIBROSIS_DSI_RNA_2026,2prime_MOE,high_PS,0.9484,high_PS,0,2prime_MOE|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_16,0.97376,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000480,OLIGO_0000480,ZHAI_GALNAC_LNP_SIMKK4_LIVER_REGEN_2026,synthetic_siRNA_payload_proxy,low_or_no_PS,0.0,low_PS,1,synthetic_siRNA_payload_proxy|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_0,0.9406,inferred_from_paper,qRT_PCR_flow_CLSM_hemolysis_live_dead_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000481,OLIGO_0000481,HUANG_AGT_GALNAC_SIRNA_TOXICOLOGY_2025,unmodified,partial_PS,0.39482,medium_PS,0,unmodified|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_10,0.94916,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000482,OLIGO_0000482,EGLI_MANOHARAN_APPROVED_OLIGO_CHEMISTRY_2023,cEt,low_or_no_PS,0.04819,low_PS,0,cEt|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_1,0.97249,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000483,OLIGO_0000483,LIVER_SPHEROID_SCHOLTEN_2026,LNA,partial_PS,0.22223,low_PS,1,LNA|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_6,0.99346,inferred_from_paper,HPLC,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000484,OLIGO_0000484,KIM_MILASEN_CUSTOM_ASO_2019,2prime_MOE,partial_PS,0.35338,medium_PS,1,2prime_MOE|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_7,0.999,inferred_from_paper,HPLC,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000485,OLIGO_0000485,MEMO_OLIGOTOX_PHASE2_ALIGNMENT,LNA,partial_PS,0.24658,low_PS,0,LNA|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_6,0.97394,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000486,OLIGO_0000486,XI_HCC_CHROMATIN_DGAT1_SIRNA_2025,2prime_MOE,low_or_no_PS,0.04594,low_PS,0,2prime_MOE|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_1,0.9785,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000487,OLIGO_0000487,DUDZICZ_ZILEBESIRAN_HTN_REVIEW_2025,2prime_OMe,partial_PS,0.18207,low_PS,1,2prime_OMe|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_4,0.99457,inferred_from_paper,LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000488,OLIGO_0000488,PNPLA3_ROMEO_VALENTI_2025,2prime_MOE,partial_PS,0.2214,low_PS,1,2prime_MOE|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_6,0.95692,inferred_from_paper,LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000489,OLIGO_0000489,HUANG_AGT_GALNAC_SIRNA_TOXICOLOGY_2025,2prime_OMe,partial_PS,0.21539,low_PS,1,2prime_OMe|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_5,0.94916,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000490,OLIGO_0000490,HAUPTMANN_SIRNA_BULGES_GALNAC_2022,2OMe_2F_alternating,partial_PS,0.12351,low_PS,1,2OMe_2F_alternating|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_2,0.90189,inferred_from_paper,qRT_PCR_ELISA_reporter_melting_LCMS_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000491,OLIGO_0000491,SCHLEGEL_ESCPLUS_SEED_PAIRING_GALNAC_SIRNA_2022,2prime_MOE,partial_PS,0.20558,low_PS,0,2prime_MOE|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_4,0.94373,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000492,OLIGO_0000492,RAPIROSIRAN_SANYAL_2025,2prime_MOE,partial_PS,0.46416,medium_PS,0,2prime_MOE|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_11,0.96483,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000493,OLIGO_0000493,HUANG_GALNAC_RBC_EV_LIVER_DISEASE_2025,ASO_anti_miR_proxy,partial_PS,0.31777,low_PS,1,ASO_anti_miR_proxy|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_6,0.97514,inferred_from_paper,PARP1_PAR_ORO_steatosis_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000494,OLIGO_0000494,PRAKASH_APOC3_LONG_ACTING_GALNAC_SIRNA_2025,LNA,partial_PS,0.59892,medium_PS,0,LNA|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_17,0.95481,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000495,OLIGO_0000495,ABULHUSN_HSD17B13_PROTECTIVE_VARIANT_2018,mixed,partial_PS,0.30296,low_PS,0,mixed|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_8,0.93966,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000496,OLIGO_0000496,KANDA_PCDHA11_AMNA_ASO_2024,AmNA,high_PS,1.0,high_PS,0,AmNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_17,0.99551,inferred_from_paper,AmNA_ASO_synthesis_HPLC_LCMS_qPCR_microarray_toxicology_generated_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000497,OLIGO_0000497,AGARWAL_GALNAC_SIRNA_OFFTARGET_2025,cEt,low_or_no_PS,0.04162,low_PS,1,cEt|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_1,0.98437,literature_grounded_generated,not_reported_generated,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000498,OLIGO_0000498,HAGEDORN_LNA_HEPATOTOX_RF_2013,LNA,high_PS,0.88023,high_PS,0,LNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_11,0.93989,inferred_from_paper,ion_exchange_HPLC_LC_MS_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000499,OLIGO_0000499,RO7239958_GERETTI_2025,LNA,partial_PS,0.56286,medium_PS,1,LNA|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_15,0.999,inferred_from_paper,not_reported_generated,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000500,OLIGO_0000500,OLSON_CHOLANGIOCYTE_CHOLESTASIS_2025,LNA,partial_PS,0.53745,medium_PS,0,LNA|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_11,0.96728,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000501,OLIGO_0000501,HUANG_AGT_GALNAC_SIRNA_TOXICOLOGY_2025,AmNA,low_or_no_PS,0.04472,low_PS,0,AmNA|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_1,0.97706,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000502,OLIGO_0000502,KIM_LARP6_HSC_FIBROSIS_DSI_RNA_2026,2prime_OMe,partial_PS,0.62592,medium_PS,0,2prime_OMe|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_13,0.98156,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000503,OLIGO_0000503,DHARA_LNA_PHOSPHOTHIOTRIESTER_SSO_CLICK_2025,2prime_F,partial_PS,0.19934,low_PS,1,2prime_F|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_4,0.94313,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000504,OLIGO_0000504,WANG_PMEVL_SEV_SMALL_RNA_PCSK9_2026,not_applicable_sEV_payload_context,low_or_no_PS,0.0,low_PS,0,not_applicable_sEV_payload_context|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_0,0.9735,literature_grounded_generated,RT_qPCR_NTA_TEM_Western_RNase_protection_IVIS_ALT_AST_H_E_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000505,OLIGO_0000505,ARMISEN_AZD2693_PNPLA3_ASO_MASH_2025,mixed,partial_PS,0.3303,low_PS,0,mixed|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_8,0.92374,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000506,OLIGO_0000506,DU_MALAT1_HBV_HCC_ASO_2025,gapmer_like_ASO_proxy,high_PS,0.70547,high_PS,0,gapmer_like_ASO_proxy|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_13,0.91258,inferred_from_paper,HBV_pgRNA_DNA_rcccDNA_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000507,OLIGO_0000507,KIM_GALNAC_SIRNA_LCMS_DPPT_2025,mixed,partial_PS,0.1121,low_PS,1,mixed|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_2,0.95262,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000508,OLIGO_0000508,BERGEN_DILIMAP_TOXPREDICTOR_DILI_2025,LNA,partial_PS,0.19489,low_PS,0,LNA|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_4,0.94832,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000509,OLIGO_0000509,ANDERSSON_PRECLINICAL_OLIGO_SAFETY_2022,AmNA,partial_PS,0.084,low_PS,1,AmNA|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_2,0.97206,literature_grounded_generated,preclinical_safety_screening_cascade_ALT_AST_kidney_complement_platelet_offtarget_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000510,OLIGO_0000510,BUREL_GAPMER_RNASEH1_LONG_PREMRNA_HEPATOTOX_2016,AmNA,partial_PS,0.37133,medium_PS,0,AmNA|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_8,0.93366,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000511,OLIGO_0000511,HUANG_AGT_GALNAC_SIRNA_TOXICOLOGY_2025,LNA,partial_PS,0.30397,low_PS,0,LNA|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_8,0.97022,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000512,OLIGO_0000512,HAGEDORN_LNA_HEPATOTOX_RF_2013,LNA,high_PS,0.93013,high_PS,0,LNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_11,0.88431,inferred_from_paper,ion_exchange_HPLC_LC_MS_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000513,OLIGO_0000513,AGARWAL_GALNAC_SIRNA_OFFTARGET_2025,mixed,partial_PS,0.53715,medium_PS,0,mixed|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_13,0.91938,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000514,OLIGO_0000514,HUANG_AGT_GALNAC_SIRNA_TOXICOLOGY_2025,2prime_F,partial_PS,0.24938,low_PS,0,2prime_F|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_6,0.999,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000515,OLIGO_0000515,YAMAGUCHI_SCPBNA2_REDUCED_HEPATOTOX_2025,mixed,high_PS,0.73442,high_PS,1,mixed|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_15,0.9624,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000516,OLIGO_0000516,YAMAGUCHI_SCPBNA2_REDUCED_HEPATOTOX_2025,AmNA,partial_PS,0.1988,low_PS,0,AmNA|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_5,0.93922,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000517,OLIGO_0000517,JANAS_GALNAC_RNAI_NONCLINICAL_SAFETY_2018,mixed,partial_PS,0.20379,low_PS,0,mixed|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_4,0.98317,literature_grounded_generated,rat_monkey_repeat_dose_toxicology_platform_safety_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000518,OLIGO_0000518,LIU_CYP2E1_LNP_APAP_AILI_2025,2prime_OMe,high_PS,0.69211,high_PS,0,2prime_OMe|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_12,0.98647,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000519,OLIGO_0000519,SUN_HCC_RNA_NANOPARTICLE_MULTITARGET_2026,cEt,partial_PS,0.49615,medium_PS,1,cEt|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_13,0.92649,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000520,OLIGO_0000520,SUBRAMANIAN_RNAI_RHEOSTAT_AAV_TRANSGENE_2023,2prime_F,partial_PS,0.49095,medium_PS,0,2prime_F|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_10,0.91335,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000521,OLIGO_0000521,HJELMGREN_PS_ASO_DDR_2026,2prime_MOE,high_PS,0.7,high_PS,0,2prime_MOE|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_17,0.98441,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000522,OLIGO_0000522,ARMISEN_AZD2693_PNPLA3_ASO_MASH_2025,2prime_MOE,high_PS,0.93213,high_PS,0,2prime_MOE|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_14,0.96009,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000523,OLIGO_0000523,AGARWAL_GALNAC_SIRNA_OFFTARGET_2025,2prime_OMe,partial_PS,0.44457,medium_PS,0,2prime_OMe|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_8,0.98608,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000524,OLIGO_0000524,JANAS_GALNAC_RNAI_NONCLINICAL_SAFETY_2018,unmodified,partial_PS,0.16281,low_PS,0,unmodified|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_3,0.97116,literature_grounded_generated,rat_monkey_repeat_dose_toxicology_platform_safety_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000525,OLIGO_0000525,RO7239958_GERETTI_2025,LNA,partial_PS,0.58164,medium_PS,1,LNA|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_12,0.96751,inferred_from_paper,HPLC,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000526,OLIGO_0000526,ARMISEN_AZD2693_PNPLA3_ASO_MASH_2025,mixed,partial_PS,0.58663,medium_PS,1,mixed|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_11,0.94785,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000527,OLIGO_0000527,YAMAGUCHI_SCPBNA2_REDUCED_HEPATOTOX_2025,AmNA,partial_PS,0.32726,low_PS,0,AmNA|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_7,0.98448,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000528,OLIGO_0000528,RAPIROSIRAN_SANYAL_2025,2prime_MOE,partial_PS,0.28255,low_PS,1,2prime_MOE|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_5,0.96464,inferred_from_paper,HPLC,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000529,OLIGO_0000529,BOSCO_INCLISIRAN_FH_REALWORLD_2025,LNA,partial_PS,0.23115,low_PS,0,LNA|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_5,0.95536,literature_grounded_generated,real_world_six_month_lipid_PWV_ALT_AST_CPK_monitoring_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000530,OLIGO_0000530,KIM_LARP6_HSC_FIBROSIS_DSI_RNA_2026,unmodified,partial_PS,0.56357,medium_PS,1,unmodified|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_11,0.96301,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000531,OLIGO_0000531,YAMAGUCHI_SCPBNA2_REDUCED_HEPATOTOX_2025,cEt,low_or_no_PS,0.03243,low_PS,0,cEt|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_1,0.94942,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000532,OLIGO_0000532,JANAS_GALNAC_RNAI_NONCLINICAL_SAFETY_2018,2prime_OMe,partial_PS,0.38759,medium_PS,0,2prime_OMe|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_8,0.95847,literature_grounded_generated,rat_monkey_repeat_dose_toxicology_platform_safety_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000533,OLIGO_0000533,JANAS_GALNAC_SIRNA_OFFTARGET_RAT_HEPATOTOX_2018,2prime_F,high_PS,0.72991,high_PS,1,2prime_F|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_16,0.93244,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000534,OLIGO_0000534,BERGEN_DILIMAP_TOXPREDICTOR_DILI_2025,unmodified,partial_PS,0.43932,medium_PS,0,unmodified|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_10,0.93525,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000535,OLIGO_0000535,EGLI_MANOHARAN_APPROVED_OLIGO_CHEMISTRY_2023,2prime_F,partial_PS,0.30218,low_PS,0,2prime_F|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_8,0.98623,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000536,OLIGO_0000536,LIVER_SPHEROID_SCHOLTEN_2026,cEt,partial_PS,0.21691,low_PS,0,cEt|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_5,0.96188,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000537,OLIGO_0000537,EGLI_MANOHARAN_APPROVED_OLIGO_CHEMISTRY_2023,AmNA,partial_PS,0.23841,low_PS,0,AmNA|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_5,0.98073,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000538,OLIGO_0000538,TERADA_BROTHERS_ASO_PNA_TOEHOLD_2023,LNA,high_PS,0.86527,high_PS,1,LNA|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_16,0.9479,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000539,OLIGO_0000539,BERGEN_DILIMAP_TOXPREDICTOR_DILI_2025,AmNA,partial_PS,0.07571,low_PS,0,AmNA|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_2,0.96202,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000540,OLIGO_0000540,MOHAMED_NANOPARTICLE_HEPATITIS_2026,2prime_OMe,partial_PS,0.4311,medium_PS,1,2prime_OMe|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_8,0.96392,inferred_from_paper,HPLC,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000541,OLIGO_0000541,OLIVER_HILL_MODEL_SELECTION_NAT_2026,mixed,high_PS,0.76771,high_PS,1,mixed|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_11,0.90543,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000542,OLIGO_0000542,DEBACKER_GALNAC_LIVER_DELIVERY_REVIEW_2020,2prime_OMe,partial_PS,0.18456,low_PS,0,2prime_OMe|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_4,0.93607,literature_grounded_generated,GalNAc_ASGPR_liver_delivery_review_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000543,OLIGO_0000543,MEKONNEN_MYC_ASIRNA_DCA_TNBC_2025,cEt,partial_PS,0.44549,medium_PS,0,cEt|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_8,0.97771,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000544,OLIGO_0000544,ALSHAER_FDA_TIDES_HARVEST_2025,cEt,partial_PS,0.33035,low_PS,0,cEt|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_7,0.99556,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000545,OLIGO_0000545,LIU_CYP2E1_LNP_APAP_AILI_2025,cEt,partial_PS,0.19072,low_PS,1,cEt|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_5,0.95377,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000546,OLIGO_0000546,BOSCO_INCLISIRAN_FH_REALWORLD_2025,2prime_OMe,partial_PS,0.0888,low_PS,1,2prime_OMe|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_2,0.97071,literature_grounded_generated,real_world_six_month_lipid_PWV_ALT_AST_CPK_monitoring_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000547,OLIGO_0000547,GANE_VIR2218_ALNHBV_HBV_RNAI_2023,mixed_ESCplus_GNA_seed,partial_PS,0.1951,low_PS,1,mixed_ESCplus_GNA_seed|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_4,0.975,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000548,OLIGO_0000548,LU_SULT1B1_SE_MASLD_2026,2prime_OMe,partial_PS,0.3137,low_PS,0,2prime_OMe|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_8,0.97259,inferred_from_paper,LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000549,OLIGO_0000549,DEBACKER_GALNAC_LIVER_DELIVERY_REVIEW_2020,unmodified,partial_PS,0.15674,low_PS,0,unmodified|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_3,0.91264,literature_grounded_generated,GalNAc_ASGPR_liver_delivery_review_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000550,OLIGO_0000550,MA_HSD17B13_ASO_FIBROSIS_MOUSE_2024,unmodified,partial_PS,0.23705,low_PS,0,unmodified|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_5,0.94003,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000551,OLIGO_0000551,LIVER_SPHEROID_SCHOLTEN_2026,mixed,low_or_no_PS,0.04097,low_PS,1,mixed|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_1,0.999,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000552,OLIGO_0000552,GOTFRID_PS_LNA_HIV_ASO_ACTIVITY_2026,unmodified,partial_PS,0.22697,low_PS,0,unmodified|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_4,0.98328,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000553,OLIGO_0000553,RAPIROSIRAN_SANYAL_2025,2prime_OMe,high_PS,0.93791,high_PS,0,2prime_OMe|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_13,0.94852,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000554,OLIGO_0000554,TERADA_BROTHERS_ASO_PNA_TOEHOLD_2023,2prime_MOE,partial_PS,0.32228,low_PS,1,2prime_MOE|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_7,0.999,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000555,OLIGO_0000555,SCHLEGEL_ESCPLUS_SEED_PAIRING_GALNAC_SIRNA_2022,unmodified,high_PS,0.79637,high_PS,0,unmodified|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_12,0.98673,literature_grounded_generated,not_reported_generated,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000556,OLIGO_0000556,RAPIROSIRAN_SANYAL_2025,LNA,partial_PS,0.17423,low_PS,1,LNA|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_3,0.95865,inferred_from_paper,HPLC+LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000557,OLIGO_0000557,SUN_HCC_RNA_NANOPARTICLE_MULTITARGET_2026,unmodified,partial_PS,0.09985,low_PS,1,unmodified|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_2,0.98577,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000558,OLIGO_0000558,GANE_VIR2218_ALNHBV_HBV_RNAI_2023,mixed_ESCplus_GNA_seed,partial_PS,0.06325,low_PS,1,mixed_ESCplus_GNA_seed|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_2,0.96148,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000559,OLIGO_0000559,LIVER_SPHEROID_SCHOLTEN_2026,AmNA,partial_PS,0.1945,low_PS,1,AmNA|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_4,0.93517,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000560,OLIGO_0000560,LU_SULT1B1_SE_MASLD_2026,2prime_OMe,partial_PS,0.62,medium_PS,1,2prime_OMe|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_12,0.94877,inferred_from_paper,mass_spectrometry,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000561,OLIGO_0000561,BOSCO_INCLISIRAN_FH_REALWORLD_2025,2prime_F,high_PS,0.89362,high_PS,0,2prime_F|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_14,0.93534,literature_grounded_generated,real_world_six_month_lipid_PWV_ALT_AST_CPK_monitoring_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000562,OLIGO_0000562,KANDA_PCDHA11_AMNA_ASO_2024,AmNA,high_PS,1.0,high_PS,0,AmNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_15,0.97081,inferred_from_paper,AmNA_ASO_synthesis_HPLC_LCMS_qPCR_microarray_toxicology_generated_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000563,OLIGO_0000563,KIM_LARP6_HSC_FIBROSIS_DSI_RNA_2026,cEt,high_PS,0.77422,high_PS,1,cEt|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_19,0.96555,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000564,OLIGO_0000564,LIVER_SPHEROID_SCHOLTEN_2026,LNA,high_PS,0.85847,high_PS,1,LNA|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_24,0.95401,inferred_from_paper,HPLC+LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000565,OLIGO_0000565,RAPIROSIRAN_SANYAL_2025,mixed,low_or_no_PS,0.01682,low_PS,1,mixed|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_0,0.95357,inferred_from_paper,mass_spectrometry,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000566,OLIGO_0000566,ANDERSSON_PRECLINICAL_OLIGO_SAFETY_2022,LNA,partial_PS,0.43858,medium_PS,0,LNA|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_10,0.95697,literature_grounded_generated,preclinical_safety_screening_cascade_ALT_AST_kidney_complement_platelet_offtarget_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000567,OLIGO_0000567,DU_MALAT1_HBV_HCC_ASO_2025,gapmer_like_ASO_proxy,partial_PS,0.48019,medium_PS,0,gapmer_like_ASO_proxy|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_9,0.98288,inferred_from_paper,HBV_pgRNA_DNA_rcccDNA_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000568,OLIGO_0000568,HUANG_GALNAC_RBC_EV_LIVER_DISEASE_2025,cholesterol_GalNAc_tethered_oligo_proxy,partial_PS,0.18725,low_PS,1,not_applicable,not_applicable,0.91495,inferred_from_paper,ALT_AST_ELISA_H_E_IHC_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000569,OLIGO_0000569,RO7239958_GERETTI_2025,LNA,high_PS,0.8809,high_PS,1,LNA|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_21,0.9671,inferred_from_paper,LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000570,OLIGO_0000570,AGARWAL_GALNAC_SIRNA_OFFTARGET_2025,AmNA,partial_PS,0.17688,low_PS,0,AmNA|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_4,0.93897,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000571,OLIGO_0000571,PRAKASH_APOC3_LONG_ACTING_GALNAC_SIRNA_2025,LNA,partial_PS,0.52413,medium_PS,1,LNA|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_14,0.93716,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000572,OLIGO_0000572,ZHAI_GALNAC_LNP_SIMKK4_LIVER_REGEN_2026,synthetic_siRNA_payload_proxy,low_or_no_PS,0.0,low_PS,1,synthetic_siRNA_payload_proxy|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_0,0.90374,inferred_from_paper,qRT_PCR_flow_CLSM_hemolysis_live_dead_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000573,OLIGO_0000573,HUANG_AGT_GALNAC_SIRNA_TOXICOLOGY_2025,2prime_F,partial_PS,0.17428,low_PS,1,2prime_F|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_3,0.98432,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000574,OLIGO_0000574,ZHU_HMMR_HCC_4MU_SIRNA_2026,2prime_MOE,partial_PS,0.06849,low_PS,1,2prime_MOE|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_1,0.97456,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000575,OLIGO_0000575,JANAS_GALNAC_SIRNA_OFFTARGET_RAT_HEPATOTOX_2018,mixed,partial_PS,0.19061,low_PS,1,mixed|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_3,0.92553,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000576,OLIGO_0000576,RO7239958_GERETTI_2025,2prime_OMe,partial_PS,0.59885,medium_PS,0,2prime_OMe|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_11,0.9779,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000577,OLIGO_0000577,HAGEDORN_LNA_HEPATOTOX_RF_2013,LNA,high_PS,0.86981,high_PS,0,LNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_11,0.88347,inferred_from_paper,ion_exchange_HPLC_LC_MS_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000578,OLIGO_0000578,SUN_HCC_RNA_NANOPARTICLE_MULTITARGET_2026,LNA,high_PS,0.78244,high_PS,0,LNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_20,0.94862,literature_grounded_generated,IFN_alpha_disulfidptosis_context_nonreducing_WB_NADPH_Factin_siRNA_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000579,OLIGO_0000579,SOUSA_HDO_MULTIFUNCTIONAL_HELA_2022,cEt,partial_PS,0.1737,low_PS,1,cEt|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_4,0.94684,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000580,OLIGO_0000580,HJELMGREN_PS_ASO_DDR_2026,RNA_PS,high_PS,0.7,high_PS,0,RNA_PS|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_17,0.96615,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000581,OLIGO_0000581,WANG_PMEVL_SEV_SMALL_RNA_PCSK9_2026,not_applicable_sEV_payload_context,low_or_no_PS,0.0,low_PS,0,not_applicable_sEV_payload_context|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_0,0.95969,literature_grounded_generated,RT_qPCR_NTA_TEM_Western_RNase_protection_IVIS_ALT_AST_H_E_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000582,OLIGO_0000582,RO7239958_GERETTI_2025,AmNA,partial_PS,0.50075,medium_PS,0,AmNA|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_13,0.999,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000583,OLIGO_0000583,KANDA_PCDHA11_AMNA_ASO_2024,AmNA,high_PS,1.0,high_PS,0,AmNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_19,0.97377,inferred_from_paper,AmNA_ASO_synthesis_HPLC_LCMS_qPCR_microarray_toxicology_generated_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000584,OLIGO_0000584,JANAS_GALNAC_RNAI_NONCLINICAL_SAFETY_2018,2prime_F,partial_PS,0.07722,low_PS,0,2prime_F|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_1,0.98701,literature_grounded_generated,rat_monkey_repeat_dose_toxicology_platform_safety_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000585,OLIGO_0000585,JIANG_LNP_CRISPR_HAO1_PH1_2025,2prime_OMe,partial_PS,0.0924,low_PS,1,2prime_OMe|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_2,0.97576,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000586,OLIGO_0000586,YAMAGUCHI_SCPBNA2_REDUCED_HEPATOTOX_2025,cEt,partial_PS,0.16592,low_PS,0,cEt|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_4,0.9646,literature_grounded_generated,not_reported_generated,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000587,OLIGO_0000587,RAPIROSIRAN_SANYAL_2025,AmNA,partial_PS,0.0665,low_PS,1,AmNA|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_2,0.96385,inferred_from_paper,HPLC,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000588,OLIGO_0000588,MOHAMED_NANOPARTICLE_HEPATITIS_2026,2prime_F,partial_PS,0.3719,medium_PS,1,2prime_F|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_9,0.95803,inferred_from_paper,HPLC,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000589,OLIGO_0000589,WANG_PMEVL_SEV_SMALL_RNA_PCSK9_2026,not_applicable_sEV_payload_context,low_or_no_PS,0.0,low_PS,0,not_applicable_sEV_payload_context|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_0,0.96844,literature_grounded_generated,RT_qPCR_NTA_TEM_Western_RNase_protection_IVIS_ALT_AST_H_E_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000590,OLIGO_0000590,HUANG_AGT_GALNAC_SIRNA_TOXICOLOGY_2025,AmNA,partial_PS,0.38879,medium_PS,0,AmNA|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_8,0.98808,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000591,OLIGO_0000591,KIM_NANP_LIPID_LIVER_TARGETING_2026,2prime_F,partial_PS,0.54431,medium_PS,0,2prime_F|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_14,0.98004,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000592,OLIGO_0000592,DUDZICZ_ZILEBESIRAN_HTN_REVIEW_2025,2prime_F,low_or_no_PS,0.0281,low_PS,1,2prime_F|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_1,0.9828,inferred_from_paper,HPLC+LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000593,OLIGO_0000593,SUBRAMANIAN_RNAI_RHEOSTAT_AAV_TRANSGENE_2023,2prime_OMe,partial_PS,0.35239,medium_PS,0,2prime_OMe|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_10,0.999,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000594,OLIGO_0000594,KIM_MILASEN_CUSTOM_ASO_2019,2prime_MOE,high_PS,1.0,high_PS,0,2prime_MOE|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_21,0.97973,inferred_from_paper,HPLC,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000595,OLIGO_0000595,SUBRAMANIAN_RNAI_RHEOSTAT_AAV_TRANSGENE_2023,mixed,partial_PS,0.65429,medium_PS,0,mixed|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_14,0.97956,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000596,OLIGO_0000596,ANDERSSON_PRECLINICAL_OLIGO_SAFETY_2022,AmNA,high_PS,0.92208,high_PS,0,AmNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_22,0.97646,literature_grounded_generated,preclinical_safety_screening_cascade_ALT_AST_kidney_complement_platelet_offtarget_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000597,OLIGO_0000597,YAMAGUCHI_SCPBNA2_REDUCED_HEPATOTOX_2025,AmNA,partial_PS,0.32324,low_PS,1,AmNA|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_6,0.97776,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000598,OLIGO_0000598,KIM_LARP6_HSC_FIBROSIS_DSI_RNA_2026,2prime_MOE,high_PS,0.96081,high_PS,0,2prime_MOE|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_13,0.94871,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000599,OLIGO_0000599,HJELMGREN_PS_ASO_DDR_2026,RNA_PS,high_PS,0.7,high_PS,0,RNA_PS|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_15,0.999,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000600,OLIGO_0000600,ALSHAER_FDA_TIDES_HARVEST_2025,unmodified,partial_PS,0.37245,medium_PS,1,unmodified|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_10,0.97626,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000601,OLIGO_0000601,KIM_GALNAC_SIRNA_LCMS_DPPT_2025,2prime_F,partial_PS,0.26005,low_PS,0,2prime_F|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_5,0.999,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000602,OLIGO_0000602,KARTOUN_MELD_PLUS_CIRRHOSIS_2017,not_applicable_clinical_risk_score_context,low_or_no_PS,0.0,low_PS,0,not_applicable,not_applicable,0.999,inferred_from_paper,EMR_structured_variables_LASSO_logistic_regression_AUROC_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000603,OLIGO_0000603,BOSCO_INCLISIRAN_FH_REALWORLD_2025,2prime_MOE,partial_PS,0.63958,medium_PS,0,2prime_MOE|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_16,0.94371,literature_grounded_generated,real_world_six_month_lipid_PWV_ALT_AST_CPK_monitoring_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000604,OLIGO_0000604,KANDA_PCDHA11_AMNA_ASO_2024,AmNA,high_PS,1.0,high_PS,0,AmNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_17,0.99222,inferred_from_paper,AmNA_ASO_synthesis_HPLC_LCMS_qPCR_microarray_toxicology_generated_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000605,OLIGO_0000605,KIM_LARP6_HSC_FIBROSIS_DSI_RNA_2026,mixed,partial_PS,0.34891,medium_PS,1,mixed|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_10,0.95801,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000606,OLIGO_0000606,ANDERSSON_PRECLINICAL_OLIGO_SAFETY_2022,2prime_MOE,partial_PS,0.38295,medium_PS,0,2prime_MOE|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_7,0.95886,literature_grounded_generated,preclinical_safety_screening_cascade_ALT_AST_kidney_complement_platelet_offtarget_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000607,OLIGO_0000607,JIANG_AOC_FREE_ASO_PAYLOAD_HYBRIDIZATION_LCMS_2024,AmNA,partial_PS,0.11706,low_PS,1,AmNA|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_2,0.92545,literature_grounded_generated,not_reported_generated,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000608,OLIGO_0000608,ZHAI_GALNAC_LNP_SIMKK4_LIVER_REGEN_2026,synthetic_siRNA_payload_proxy,low_or_no_PS,0.0,low_PS,1,synthetic_siRNA_payload_proxy|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_0,0.93901,inferred_from_paper,Western_IF_p38_JNK_ATF2_ELK1_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000609,OLIGO_0000609,PRAKASH_APOC3_LONG_ACTING_GALNAC_SIRNA_2025,mixed,partial_PS,0.14567,low_PS,0,mixed|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_4,0.96943,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000610,OLIGO_0000610,KANDA_PCDHA11_AMNA_ASO_2024,AmNA,high_PS,1.0,high_PS,0,AmNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_17,0.98127,inferred_from_paper,AmNA_ASO_synthesis_HPLC_LCMS_qPCR_microarray_toxicology_generated_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000611,OLIGO_0000611,ARMISEN_AZD2693_PNPLA3_ASO_MASH_2025,cEt,partial_PS,0.11773,low_PS,1,cEt|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_3,0.96237,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000612,OLIGO_0000612,MA_HSD17B13_ASO_FIBROSIS_MOUSE_2024,2prime_F,partial_PS,0.21715,low_PS,0,2prime_F|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_6,0.96594,literature_grounded_generated,not_reported_generated,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000613,OLIGO_0000613,HAUPTMANN_SIRNA_BULGES_GALNAC_2022,2OMe_2F_alternating,partial_PS,0.10642,low_PS,1,2OMe_2F_alternating|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_2,0.94295,inferred_from_paper,qRT_PCR_ELISA_reporter_melting_LCMS_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000614,OLIGO_0000614,ENGELBEEN_ALK4_MUSCLE_SIRNA_2023,mixed,partial_PS,0.33955,medium_PS,0,mixed|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_10,0.98331,inferred_from_paper,mass_spectrometry,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000615,OLIGO_0000615,LIVER_SPHEROID_SCHOLTEN_2026,LNA,high_PS,0.67055,high_PS,1,LNA|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_15,0.95186,inferred_from_paper,HPLC,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000616,OLIGO_0000616,JIANG_LNP_CRISPR_HAO1_PH1_2025,2prime_F,partial_PS,0.27992,low_PS,0,2prime_F|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_7,0.99087,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000617,OLIGO_0000617,WANG_PMEVL_SEV_SMALL_RNA_PCSK9_2026,not_applicable_sEV_payload_context,low_or_no_PS,0.0,low_PS,0,not_applicable_sEV_payload_context|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_0,0.98787,literature_grounded_generated,RT_qPCR_NTA_TEM_Western_RNase_protection_IVIS_ALT_AST_H_E_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000618,OLIGO_0000618,JANAS_GALNAC_RNAI_NONCLINICAL_SAFETY_2018,cEt,partial_PS,0.37759,medium_PS,0,cEt|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_6,0.97627,literature_grounded_generated,rat_monkey_repeat_dose_toxicology_platform_safety_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000619,OLIGO_0000619,HJELMGREN_PS_ASO_DDR_2026,LNA_mixed,high_PS,0.7,high_PS,0,LNA_mixed|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_10,0.98265,literature_grounded_generated,not_reported_generated,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000620,OLIGO_0000620,JIANG_LNP_CRISPR_HAO1_PH1_2025,LNA,partial_PS,0.13796,low_PS,0,LNA|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_3,0.95028,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000621,OLIGO_0000621,RO7239958_GERETTI_2025,LNA,high_PS,0.83217,high_PS,1,LNA|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_16,0.95714,inferred_from_paper,HPLC+LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000622,OLIGO_0000622,WANG_PMEVL_SEV_SMALL_RNA_PCSK9_2026,not_applicable_sEV_payload_context,low_or_no_PS,0.0,low_PS,0,not_applicable_sEV_payload_context|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_0,0.95786,literature_grounded_generated,RT_qPCR_NTA_TEM_Western_RNase_protection_IVIS_ALT_AST_H_E_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000623,OLIGO_0000623,JIANG_LNP_CRISPR_HAO1_PH1_2025,2prime_F,high_PS,0.74478,high_PS,0,2prime_F|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_18,0.96999,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000624,OLIGO_0000624,XIE_FBLL1_HCC_SPATIAL_MULTIOMICS_2026,unmodified_or_research_siRNA_proxy,partial_PS,0.13147,low_PS,0,unmodified_or_research_siRNA_proxy|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_3,0.95491,inferred_from_paper,qRT_PCR_CCK8_colony_formation_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000625,OLIGO_0000625,JANAS_GALNAC_RNAI_NONCLINICAL_SAFETY_2018,2prime_F,high_PS,0.94757,high_PS,0,2prime_F|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_16,0.95272,literature_grounded_generated,rat_monkey_repeat_dose_toxicology_platform_safety_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000626,OLIGO_0000626,JANAS_GALNAC_SIRNA_OFFTARGET_RAT_HEPATOTOX_2018,unmodified,partial_PS,0.20154,low_PS,0,unmodified|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_4,0.94185,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000627,OLIGO_0000627,UMEZU_ORAL_MIR29A_LIVER_FIBROSIS_NA_2025,mixed,partial_PS,0.35576,medium_PS,0,mixed|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_6,0.97655,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000628,OLIGO_0000628,HJELMGREN_PS_ASO_DDR_2026,LNA_mixed,high_PS,0.7,high_PS,0,LNA_mixed|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_15,0.99867,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000629,OLIGO_0000629,MEKONNEN_MYC_ASIRNA_DCA_TNBC_2025,LNA,partial_PS,0.23919,low_PS,0,LNA|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_4,0.9649,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000630,OLIGO_0000630,KANDA_PCDHA11_AMNA_ASO_2024,AmNA,high_PS,1.0,high_PS,0,AmNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_17,0.97605,inferred_from_paper,AmNA_ASO_synthesis_HPLC_LCMS_qPCR_microarray_toxicology_generated_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000631,OLIGO_0000631,HUANG_AGT_GALNAC_SIRNA_TOXICOLOGY_2025,mixed,low_or_no_PS,0.02072,low_PS,0,mixed|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_0,0.9283,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000632,OLIGO_0000632,TERADA_BROTHERS_ASO_PNA_TOEHOLD_2023,AmNA,low_or_no_PS,0.00167,low_PS,0,AmNA|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_0,0.93606,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000633,OLIGO_0000633,RO7239958_GERETTI_2025,2prime_OMe,partial_PS,0.2096,low_PS,0,2prime_OMe|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_4,0.98967,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000634,OLIGO_0000634,YAMAGUCHI_SCPBNA2_REDUCED_HEPATOTOX_2025,mixed,partial_PS,0.3961,medium_PS,0,mixed|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_10,0.94882,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000635,OLIGO_0000635,RAPIROSIRAN_SANYAL_2025,unmodified,partial_PS,0.55995,medium_PS,0,unmodified|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_12,0.97154,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000636,OLIGO_0000636,RO7239958_GERETTI_2025,LNA,high_PS,0.76673,high_PS,1,LNA|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_20,0.95481,inferred_from_paper,LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000637,OLIGO_0000637,LIU_CYP2E1_LNP_APAP_AILI_2025,mixed,partial_PS,0.56736,medium_PS,1,mixed|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_14,0.999,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000638,OLIGO_0000638,GANE_VIR2218_ALNHBV_HBV_RNAI_2023,mixed_ESCplus_GNA_seed,partial_PS,0.60496,medium_PS,1,mixed_ESCplus_GNA_seed|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_16,0.94954,literature_grounded_generated,not_reported_generated,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000639,OLIGO_0000639,TERADA_BROTHERS_ASO_PNA_TOEHOLD_2023,LNA,partial_PS,0.43985,medium_PS,1,LNA|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_10,0.90768,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000640,OLIGO_0000640,LIVER_SPHEROID_SCHOLTEN_2026,2prime_F,partial_PS,0.17327,low_PS,1,2prime_F|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_4,0.94921,inferred_from_paper,LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000641,OLIGO_0000641,GANE_VIR2218_ALNHBV_HBV_RNAI_2023,mixed_ESC_parent,partial_PS,0.12939,low_PS,1,mixed_ESC_parent|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_2,0.96958,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000642,OLIGO_0000642,XIE_FBLL1_HCC_SPATIAL_MULTIOMICS_2026,unmodified_or_research_siRNA_proxy,partial_PS,0.18147,low_PS,0,unmodified_or_research_siRNA_proxy|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_3,0.95715,inferred_from_paper,qRT_PCR_CCK8_colony_formation_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000643,OLIGO_0000643,WANG_OGT_SEV_LSEC_MASLD_2026,not_applicable,low_or_no_PS,0.0,low_PS,0,not_applicable,not_applicable,0.88982,inferred_from_paper,ALT_AST_TG_inflammation_histology_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000644,OLIGO_0000644,QU_CPG_ODN_APAP_TLR9_IRG1_2025,unmodified,partial_PS,0.29561,low_PS,1,unmodified|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_6,0.96556,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000645,OLIGO_0000645,HUANG_GALNAC_RBC_EV_LIVER_DISEASE_2025,ASO_anti_miR_proxy,partial_PS,0.12573,low_PS,1,ASO_anti_miR_proxy|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_3,0.91109,inferred_from_paper,Rab7_siRNA_PJ34_HCC_retention_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000646,OLIGO_0000646,KARTOUN_MELD_PLUS_CIRRHOSIS_2017,not_applicable_clinical_risk_score_context,low_or_no_PS,0.0,low_PS,0,not_applicable,not_applicable,0.99878,inferred_from_paper,EMR_structured_variables_LASSO_logistic_regression_AUROC_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000647,OLIGO_0000647,LIVER_SPHEROID_SCHOLTEN_2026,2prime_MOE,low_or_no_PS,0.0077,low_PS,1,2prime_MOE|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_0,0.99812,inferred_from_paper,mass_spectrometry,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000648,OLIGO_0000648,BOSCO_INCLISIRAN_FH_REALWORLD_2025,2prime_OMe,high_PS,0.68537,high_PS,1,2prime_OMe|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_14,0.92251,literature_grounded_generated,real_world_six_month_lipid_PWV_ALT_AST_CPK_monitoring_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000649,OLIGO_0000649,LIVER_SPHEROID_SCHOLTEN_2026,unmodified,high_PS,0.83399,high_PS,1,unmodified|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_12,0.93323,inferred_from_paper,not_reported_generated,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000650,OLIGO_0000650,OLIVER_HILL_MODEL_SELECTION_NAT_2026,unmodified,partial_PS,0.0567,low_PS,1,unmodified|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_1,0.95645,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000651,OLIGO_0000651,JIANG_LNP_CRISPR_HAO1_PH1_2025,2prime_OMe,partial_PS,0.15285,low_PS,0,2prime_OMe|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_4,0.999,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000652,OLIGO_0000652,ALSHAER_FDA_TIDES_HARVEST_2025,cEt,partial_PS,0.2671,low_PS,0,cEt|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_5,0.89879,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000653,OLIGO_0000653,JIANG_AOC_FREE_ASO_PAYLOAD_HYBRIDIZATION_LCMS_2024,cEt,partial_PS,0.29097,low_PS,0,cEt|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_7,0.94387,literature_grounded_generated,not_reported_generated,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000654,OLIGO_0000654,HUANG_GALNAC_RBC_EV_LIVER_DISEASE_2025,ASO_anti_miR_proxy,partial_PS,0.18643,low_PS,1,ASO_anti_miR_proxy|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_4,0.92117,inferred_from_paper,ALT_AST_ELISA_H_E_IHC_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000655,OLIGO_0000655,ABULHUSN_HSD17B13_PROTECTIVE_VARIANT_2018,AmNA,partial_PS,0.45901,medium_PS,0,AmNA|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_8,0.96332,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000656,OLIGO_0000656,ZHAI_GALNAC_LNP_SIMKK4_LIVER_REGEN_2026,synthetic_siRNA_payload_proxy,low_or_no_PS,0.0,low_PS,1,synthetic_siRNA_payload_proxy|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_0,0.94165,inferred_from_paper,MicroCT_H_E_Ki67_TUNEL_biochemistry_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000657,OLIGO_0000657,DU_MALAT1_HBV_HCC_ASO_2025,gapmer_like_ASO_proxy,partial_PS,0.45726,medium_PS,0,gapmer_like_ASO_proxy|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_8,0.88752,inferred_from_paper,qRT_PCR_FISH_MeRIP_RIP_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000658,OLIGO_0000658,XU_FGF21_MAPK1_DAIRY_KETOSIS_SIRNA_2025,2prime_OMe,partial_PS,0.40801,medium_PS,0,2prime_OMe|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_9,0.93722,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000659,OLIGO_0000659,JANAS_GALNAC_RNAI_NONCLINICAL_SAFETY_2018,mixed,high_PS,0.83672,high_PS,0,mixed|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_15,0.96583,literature_grounded_generated,rat_monkey_repeat_dose_toxicology_platform_safety_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000660,OLIGO_0000660,BI_IFNA_DISULFIDPTOSIS_HCC_2026,LNA,high_PS,0.73442,high_PS,0,LNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_14,0.98725,literature_grounded_generated,IFN_alpha_disulfidptosis_context_nonreducing_WB_NADPH_Factin_siRNA_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000661,OLIGO_0000661,GANE_VIR2218_ALNHBV_HBV_RNAI_2023,mixed_ESCplus_GNA_seed,partial_PS,0.17973,low_PS,1,mixed_ESCplus_GNA_seed|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_4,0.9352,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000662,OLIGO_0000662,PNPLA3_ROMEO_VALENTI_2025,unmodified,low_or_no_PS,0.02915,low_PS,0,unmodified|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_1,0.96026,inferred_from_paper,HPLC+LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000663,OLIGO_0000663,JANAS_GALNAC_RNAI_NONCLINICAL_SAFETY_2018,2prime_OMe,high_PS,0.8777,high_PS,0,2prime_OMe|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_19,0.93271,literature_grounded_generated,rat_monkey_repeat_dose_toxicology_platform_safety_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000664,OLIGO_0000664,YAMAGUCHI_SCPBNA2_REDUCED_HEPATOTOX_2025,mixed,partial_PS,0.1741,low_PS,0,mixed|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_4,0.97076,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000665,OLIGO_0000665,RO7239958_GERETTI_2025,LNA,partial_PS,0.45,medium_PS,1,LNA|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_9,0.93532,inferred_from_paper,mass_spectrometry,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000666,OLIGO_0000666,UMEZU_ORAL_MIR29A_LIVER_FIBROSIS_NA_2025,cEt,partial_PS,0.1788,low_PS,1,cEt|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_3,0.96563,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000667,OLIGO_0000667,GANE_VIR2218_ALNHBV_HBV_RNAI_2023,mixed_ESC_parent,partial_PS,0.66614,medium_PS,1,mixed_ESC_parent|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_13,0.91991,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000668,OLIGO_0000668,ENGELBEEN_ALK4_MUSCLE_SIRNA_2023,cEt,low_or_no_PS,0.01614,low_PS,0,cEt|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_0,0.999,inferred_from_paper,HPLC,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000669,OLIGO_0000669,RO7239958_GERETTI_2025,LNA,partial_PS,0.45,medium_PS,1,LNA|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_8,0.96173,inferred_from_paper,HPLC,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000670,OLIGO_0000670,KIM_LARP6_HSC_FIBROSIS_DSI_RNA_2026,2prime_MOE,partial_PS,0.05442,low_PS,0,2prime_MOE|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_1,0.999,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000671,OLIGO_0000671,JANAS_GALNAC_SIRNA_OFFTARGET_RAT_HEPATOTOX_2018,unmodified,low_or_no_PS,0.04879,low_PS,0,unmodified|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_1,0.97609,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000672,OLIGO_0000672,ZHAI_GALNAC_LNP_SIMKK4_LIVER_REGEN_2026,synthetic_siRNA_payload_proxy,low_or_no_PS,0.0,low_PS,1,synthetic_siRNA_payload_proxy|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_0,0.9253,inferred_from_paper,MicroCT_H_E_Ki67_TUNEL_biochemistry_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000673,OLIGO_0000673,ALSHAER_FDA_TIDES_HARVEST_2025,cEt,partial_PS,0.47077,medium_PS,1,cEt|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_9,0.93832,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000674,OLIGO_0000674,PNPLA3_ROMEO_VALENTI_2025,2prime_OMe,partial_PS,0.58,medium_PS,1,2prime_OMe|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_13,0.97999,inferred_from_paper,HPLC,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000675,OLIGO_0000675,GANE_VIR2218_ALNHBV_HBV_RNAI_2023,mixed_ESC_parent,partial_PS,0.30982,low_PS,1,mixed_ESC_parent|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_7,0.91663,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000676,OLIGO_0000676,OLSON_CHOLANGIOCYTE_CHOLESTASIS_2025,LNA,partial_PS,0.50952,medium_PS,1,LNA|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_13,0.95592,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000677,OLIGO_0000677,JANAS_GALNAC_SIRNA_OFFTARGET_RAT_HEPATOTOX_2018,cEt,partial_PS,0.4762,medium_PS,0,cEt|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_9,0.96025,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000678,OLIGO_0000678,MA_HSD17B13_ASO_FIBROSIS_MOUSE_2024,AmNA,partial_PS,0.41677,medium_PS,0,AmNA|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_9,0.95823,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000679,OLIGO_0000679,HAUPTMANN_SIRNA_BULGES_GALNAC_2022,2OMe_2F_alternating,partial_PS,0.14306,low_PS,1,2OMe_2F_alternating|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_3,0.95471,inferred_from_paper,qRT_PCR_ELISA_reporter_melting_LCMS_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000680,OLIGO_0000680,KIM_NANP_LIPID_LIVER_TARGETING_2026,mixed,partial_PS,0.22271,low_PS,1,mixed|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_4,0.95315,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000681,OLIGO_0000681,AGARWAL_GALNAC_SIRNA_OFFTARGET_2025,LNA,partial_PS,0.11993,low_PS,0,LNA|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_2,0.999,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000682,OLIGO_0000682,KANDA_PCDHA11_AMNA_ASO_2024,AmNA,high_PS,1.0,high_PS,0,AmNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_19,0.98048,inferred_from_paper,AmNA_ASO_synthesis_HPLC_LCMS_qPCR_microarray_toxicology_generated_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000683,OLIGO_0000683,ANDERSSON_PRECLINICAL_OLIGO_SAFETY_2022,2prime_OMe,partial_PS,0.25362,low_PS,0,2prime_OMe|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_6,0.96065,literature_grounded_generated,preclinical_safety_screening_cascade_ALT_AST_kidney_complement_platelet_offtarget_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000684,OLIGO_0000684,EGLI_MANOHARAN_APPROVED_OLIGO_CHEMISTRY_2023,2prime_MOE,partial_PS,0.31472,low_PS,1,2prime_MOE|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_7,0.97946,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000685,OLIGO_0000685,ALSHAER_FDA_TIDES_HARVEST_2025,2prime_OMe,partial_PS,0.49544,medium_PS,0,2prime_OMe|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_11,0.97359,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000686,OLIGO_0000686,GANE_VIR2218_ALNHBV_HBV_RNAI_2023,mixed_ESC_parent,partial_PS,0.32339,low_PS,1,mixed_ESC_parent|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_8,0.999,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000687,OLIGO_0000687,BERGEN_DILIMAP_TOXPREDICTOR_DILI_2025,2prime_MOE,partial_PS,0.3974,medium_PS,0,2prime_MOE|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_10,0.94069,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000688,OLIGO_0000688,JANAS_GALNAC_RNAI_NONCLINICAL_SAFETY_2018,LNA,high_PS,0.77061,high_PS,0,LNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_20,0.96341,literature_grounded_generated,rat_monkey_repeat_dose_toxicology_platform_safety_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000689,OLIGO_0000689,ELGHAZZI_GENE_SILENCING_GI_GU_TUMORS_REVIEW_2025,LNA,partial_PS,0.06083,low_PS,0,LNA|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_1,0.97,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000690,OLIGO_0000690,GOTFRID_PS_LNA_HIV_ASO_ACTIVITY_2026,2prime_OMe,high_PS,0.91739,high_PS,0,2prime_OMe|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_26,0.9682,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000691,OLIGO_0000691,PRAKASH_APOC3_LONG_ACTING_GALNAC_SIRNA_2025,2prime_F,partial_PS,0.09845,low_PS,1,2prime_F|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_2,0.95631,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000692,OLIGO_0000692,KARTOUN_MELD_PLUS_CIRRHOSIS_2017,not_applicable_clinical_risk_score_context,low_or_no_PS,0.0,low_PS,0,not_applicable,not_applicable,0.999,inferred_from_paper,EMR_structured_variables_LASSO_logistic_regression_AUROC_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000693,OLIGO_0000693,ARMISEN_AZD2693_PNPLA3_ASO_MASH_2025,LNA,partial_PS,0.14582,low_PS,0,LNA|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_3,0.99135,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000694,OLIGO_0000694,RAPIROSIRAN_SANYAL_2025,AmNA,partial_PS,0.19264,low_PS,0,AmNA|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_4,0.9101,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000695,OLIGO_0000695,HAGEDORN_LNA_HEPATOTOX_RF_2013,LNA,high_PS,0.7569,high_PS,0,LNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_10,0.85,inferred_from_paper,ion_exchange_HPLC_LC_MS_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000696,OLIGO_0000696,PNPLA3_ROMEO_VALENTI_2025,mixed,partial_PS,0.60596,medium_PS,0,mixed|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_15,0.92394,inferred_from_paper,LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000697,OLIGO_0000697,LIVER_SPHEROID_SCHOLTEN_2026,AmNA,partial_PS,0.29297,low_PS,1,AmNA|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_6,0.96369,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000698,OLIGO_0000698,SUN_HCC_RNA_NANOPARTICLE_MULTITARGET_2026,cEt,partial_PS,0.52438,medium_PS,1,cEt|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_13,0.99525,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000699,OLIGO_0000699,AGARWAL_GALNAC_SIRNA_OFFTARGET_2025,2prime_OMe,partial_PS,0.21103,low_PS,0,2prime_OMe|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_5,0.97391,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000700,OLIGO_0000700,AGARWAL_GALNAC_SIRNA_OFFTARGET_2025,2prime_F,partial_PS,0.16992,low_PS,0,2prime_F|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_3,0.999,literature_grounded_generated,not_reported_generated,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000701,OLIGO_0000701,RO7239958_GERETTI_2025,LNA,high_PS,0.89296,high_PS,1,LNA|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_20,0.92183,inferred_from_paper,HPLC,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000702,OLIGO_0000702,OLSON_CHOLANGIOCYTE_CHOLESTASIS_2025,2prime_F,partial_PS,0.50808,medium_PS,1,2prime_F|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_13,0.96857,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000703,OLIGO_0000703,HAUPTMANN_SIRNA_BULGES_GALNAC_2022,2OMe_2F_alternating,partial_PS,0.20641,low_PS,0,2OMe_2F_alternating|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_4,0.91566,inferred_from_paper,qRT_PCR_ELISA_reporter_melting_LCMS_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000704,OLIGO_0000704,LAN_SIRUBICON_ROS_GALNAC_MASH_2025,mixed_2prime_F_2prime_OMe_siRNA,partial_PS,0.28,low_PS,1,mixed_2prime_F_2prime_OMe_siRNA|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_7,0.93833,inferred_from_paper,nanoparticle_DLS_zeta_biodistribution_Rubicon_knockdown_ALT_AST_generated_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000705,OLIGO_0000705,HJELMGREN_PS_ASO_DDR_2026,RNA_PS,high_PS,0.86187,high_PS,0,RNA_PS|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_22,0.94482,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000706,OLIGO_0000706,CROOKE_RNA_TARGETED_THERAPEUTICS_2018,2prime_F,partial_PS,0.05792,low_PS,1,2prime_F|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_2,0.93101,literature_grounded_generated,not_reported_generated,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000707,OLIGO_0000707,CROOKE_RNA_TARGETED_THERAPEUTICS_2018,AmNA,partial_PS,0.31087,low_PS,0,AmNA|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_7,0.97892,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000708,OLIGO_0000708,ZHAI_GALNAC_LNP_SIMKK4_LIVER_REGEN_2026,synthetic_siRNA_payload_proxy,low_or_no_PS,0.0,low_PS,1,synthetic_siRNA_payload_proxy|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_0,0.89183,inferred_from_paper,Western_IF_p38_JNK_ATF2_ELK1_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000709,OLIGO_0000709,MENG_HYBRID_RNA_LNP_HCC_2025,unmodified,partial_PS,0.46759,medium_PS,0,unmodified|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_9,0.97939,inferred_from_paper,HPLC+LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000710,OLIGO_0000710,BUREL_GAPMER_RNASEH1_LONG_PREMRNA_HEPATOTOX_2016,LNA,high_PS,0.96128,high_PS,1,LNA|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_23,0.98952,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000711,OLIGO_0000711,MOHAMED_NANOPARTICLE_HEPATITIS_2026,LNA,low_or_no_PS,0.00802,low_PS,1,LNA|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_0,0.96371,inferred_from_paper,HPLC+LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000712,OLIGO_0000712,OLSON_CHOLANGIOCYTE_CHOLESTASIS_2025,mixed,partial_PS,0.08095,low_PS,1,mixed|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_2,0.9817,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000713,OLIGO_0000713,BERGEN_DILIMAP_TOXPREDICTOR_DILI_2025,2prime_F,high_PS,0.92495,high_PS,0,2prime_F|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_23,0.999,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000714,OLIGO_0000714,KIM_LARP6_HSC_FIBROSIS_DSI_RNA_2026,2prime_F,high_PS,0.94301,high_PS,0,2prime_F|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_19,0.98138,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000715,OLIGO_0000715,RAPIROSIRAN_SANYAL_2025,unmodified,partial_PS,0.0817,low_PS,0,unmodified|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_2,0.98657,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000716,OLIGO_0000716,ABULHUSN_HSD17B13_PROTECTIVE_VARIANT_2018,2prime_OMe,partial_PS,0.1666,low_PS,0,2prime_OMe|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_4,0.98345,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000717,OLIGO_0000717,GANE_VIR2218_ALNHBV_HBV_RNAI_2023,mixed_ESCplus_GNA_seed,partial_PS,0.23294,low_PS,1,mixed_ESCplus_GNA_seed|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_5,0.97965,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000718,OLIGO_0000718,ABULHUSN_HSD17B13_PROTECTIVE_VARIANT_2018,2prime_OMe,partial_PS,0.21884,low_PS,0,2prime_OMe|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_5,0.94462,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000719,OLIGO_0000719,UMEZU_ORAL_MIR29A_LIVER_FIBROSIS_NA_2025,2prime_OMe,partial_PS,0.50771,medium_PS,0,2prime_OMe|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_13,0.999,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000720,OLIGO_0000720,DEBACKER_GALNAC_LIVER_DELIVERY_REVIEW_2020,2prime_MOE,partial_PS,0.3149,low_PS,1,2prime_MOE|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_8,0.93947,literature_grounded_generated,GalNAc_ASGPR_liver_delivery_review_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000721,OLIGO_0000721,BERGEN_DILIMAP_TOXPREDICTOR_DILI_2025,cEt,partial_PS,0.64172,medium_PS,0,cEt|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_11,0.93321,literature_grounded_generated,not_reported_generated,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000722,OLIGO_0000722,RO7239958_GERETTI_2025,2prime_F,high_PS,0.72366,high_PS,0,2prime_F|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_12,0.9902,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000723,OLIGO_0000723,JIANG_AOC_FREE_ASO_PAYLOAD_HYBRIDIZATION_LCMS_2024,2prime_OMe,high_PS,0.81066,high_PS,0,2prime_OMe|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_19,0.999,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000724,OLIGO_0000724,MA_HSD17B13_ASO_FIBROSIS_MOUSE_2024,2prime_MOE,partial_PS,0.12249,low_PS,0,2prime_MOE|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_2,0.999,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000725,OLIGO_0000725,WANG_PMEVL_SEV_SMALL_RNA_PCSK9_2026,not_applicable_sEV_payload_context,low_or_no_PS,0.0,low_PS,0,not_applicable_sEV_payload_context|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_0,0.98002,literature_grounded_generated,RT_qPCR_NTA_TEM_Western_RNase_protection_IVIS_ALT_AST_H_E_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000726,OLIGO_0000726,SUBRAMANIAN_RNAI_RHEOSTAT_AAV_TRANSGENE_2023,unmodified,low_or_no_PS,0.02168,low_PS,0,unmodified|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_0,0.93558,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000727,OLIGO_0000727,LIVER_SPHEROID_SCHOLTEN_2026,2prime_F,partial_PS,0.05898,low_PS,1,2prime_F|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_1,0.93579,inferred_from_paper,HPLC,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000728,OLIGO_0000728,LI_AIH_CERNA_NETWORK_2022,mixed,high_PS,0.67048,high_PS,0,mixed|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_16,0.98071,literature_grounded_generated,IFN_alpha_disulfidptosis_context_nonreducing_WB_NADPH_Factin_siRNA_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000729,OLIGO_0000729,ANDERSSON_PRECLINICAL_OLIGO_SAFETY_2022,LNA,partial_PS,0.09965,low_PS,0,LNA|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_2,0.9961,literature_grounded_generated,preclinical_safety_screening_cascade_ALT_AST_kidney_complement_platelet_offtarget_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000730,OLIGO_0000730,SUN_HCC_RNA_NANOPARTICLE_MULTITARGET_2026,mixed,high_PS,0.76249,high_PS,1,mixed|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_11,0.96455,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000731,OLIGO_0000731,RO7239958_GERETTI_2025,LNA,high_PS,0.90787,high_PS,1,LNA|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_21,0.95777,inferred_from_paper,mass_spectrometry,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000732,OLIGO_0000732,DUDZICZ_ZILEBESIRAN_HTN_REVIEW_2025,mixed,partial_PS,0.32043,low_PS,1,mixed|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_7,0.92801,inferred_from_paper,mass_spectrometry,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000733,OLIGO_0000733,ARMISEN_AZD2693_PNPLA3_ASO_MASH_2025,2prime_OMe,partial_PS,0.19167,low_PS,0,2prime_OMe|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_4,0.9682,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000734,OLIGO_0000734,SUN_HCC_RNA_NANOPARTICLE_MULTITARGET_2026,unmodified,partial_PS,0.66977,high_PS,0,unmodified|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_13,0.94206,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000735,OLIGO_0000735,HAUPTMANN_SIRNA_BULGES_GALNAC_2022,2OMe_2F_alternating,partial_PS,0.09023,low_PS,1,2OMe_2F_alternating|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_2,0.89465,inferred_from_paper,qRT_PCR_ELISA_reporter_melting_LCMS_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000736,OLIGO_0000736,MENG_HYBRID_RNA_LNP_HCC_2025,LNA,partial_PS,0.26835,low_PS,0,LNA|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_6,0.96106,inferred_from_paper,HPLC,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000737,OLIGO_0000737,HJELMGREN_PS_ASO_DDR_2026,DNA_PS,high_PS,0.76372,high_PS,0,DNA_PS|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_15,0.96066,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000738,OLIGO_0000738,LAN_SIRUBICON_ROS_GALNAC_MASH_2025,mixed_2prime_F_2prime_OMe_siRNA,partial_PS,0.27604,low_PS,1,mixed_2prime_F_2prime_OMe_siRNA|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_7,0.95793,inferred_from_paper,nanoparticle_DLS_zeta_biodistribution_Rubicon_knockdown_ALT_AST_generated_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000739,OLIGO_0000739,LIVER_SPHEROID_SCHOLTEN_2026,cEt,partial_PS,0.65369,medium_PS,1,cEt|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_16,0.94609,inferred_from_paper,mass_spectrometry,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000740,OLIGO_0000740,QU_CPG_ODN_APAP_TLR9_IRG1_2025,AmNA,partial_PS,0.28202,low_PS,1,AmNA|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_5,0.99798,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000741,OLIGO_0000741,RAPIROSIRAN_SANYAL_2025,mixed,high_PS,0.87476,high_PS,0,mixed|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_14,0.999,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000742,OLIGO_0000742,HJELMGREN_PS_ASO_DDR_2026,LNA_mixed,high_PS,0.87064,high_PS,1,LNA_mixed|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_17,0.97786,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000743,OLIGO_0000743,KIM_NANP_LIPID_LIVER_TARGETING_2026,LNA,partial_PS,0.19831,low_PS,1,LNA|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_4,0.999,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000744,OLIGO_0000744,HAGEDORN_LNA_HEPATOTOX_RF_2013,LNA,high_PS,1.0,high_PS,0,LNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_13,0.87256,inferred_from_paper,ion_exchange_HPLC_LC_MS_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000745,OLIGO_0000745,RAPIROSIRAN_SANYAL_2025,2prime_MOE,partial_PS,0.38337,medium_PS,1,2prime_MOE|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_11,0.95168,inferred_from_paper,LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000746,OLIGO_0000746,HAGEDORN_LNA_HEPATOTOX_RF_2013,LNA,high_PS,0.88845,high_PS,0,LNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_13,0.94309,inferred_from_paper,ion_exchange_HPLC_LC_MS_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000747,OLIGO_0000747,AGARWAL_GALNAC_SIRNA_OFFTARGET_2025,mixed,partial_PS,0.251,low_PS,0,mixed|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_6,0.96678,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000748,OLIGO_0000748,DEBACKER_GALNAC_LIVER_DELIVERY_REVIEW_2020,2prime_MOE,partial_PS,0.18029,low_PS,0,2prime_MOE|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_4,0.98118,literature_grounded_generated,GalNAc_ASGPR_liver_delivery_review_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000749,OLIGO_0000749,ARMISEN_AZD2693_PNPLA3_ASO_MASH_2025,2prime_OMe,partial_PS,0.13684,low_PS,0,2prime_OMe|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_3,0.95964,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000750,OLIGO_0000750,ZHAI_GALNAC_LNP_SIMKK4_LIVER_REGEN_2026,synthetic_siRNA_payload_proxy,low_or_no_PS,0.0,low_PS,1,synthetic_siRNA_payload_proxy|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_0,0.88898,inferred_from_paper,Western_IF_p38_JNK_ATF2_ELK1_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000751,OLIGO_0000751,WANG_OGT_SEV_LSEC_MASLD_2026,not_applicable,low_or_no_PS,0.0,low_PS,0,not_applicable,not_applicable,0.91395,inferred_from_paper,NTA_TEM_Western_sEV_marker_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000752,OLIGO_0000752,SUN_HCC_RNA_NANOPARTICLE_MULTITARGET_2026,2prime_F,partial_PS,0.29359,low_PS,0,2prime_F|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_7,0.999,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000753,OLIGO_0000753,KIM_LARP6_HSC_FIBROSIS_DSI_RNA_2026,2prime_MOE,partial_PS,0.06592,low_PS,0,2prime_MOE|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_1,0.94633,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000754,OLIGO_0000754,DUDZICZ_ZILEBESIRAN_HTN_REVIEW_2025,2prime_F,partial_PS,0.29619,low_PS,1,2prime_F|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_7,0.97077,inferred_from_paper,HPLC+LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000755,OLIGO_0000755,CHEN_OVARIAN_MTTP_APOB_MIPOMERSEN_2025,2prime_F,partial_PS,0.24253,low_PS,0,2prime_F|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_4,0.92545,inferred_from_paper,mass_spectrometry,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000756,OLIGO_0000756,KIM_GALNAC_SIRNA_LCMS_DPPT_2025,LNA,partial_PS,0.37925,medium_PS,0,LNA|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_9,0.9542,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000757,OLIGO_0000757,LI_FXR_JNK_G0S2_TRIPTOLIDE_HEPATOTOXICITY_2025,LNA,partial_PS,0.09883,low_PS,0,LNA|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_2,0.94002,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000758,OLIGO_0000758,TERADA_BROTHERS_ASO_PNA_TOEHOLD_2023,2prime_F,low_or_no_PS,0.03653,low_PS,0,2prime_F|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_1,0.98765,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000759,OLIGO_0000759,PAN_CD133_MASLD_HCC_SIRNA_2025,2prime_OMe_pyrimidine_modified_siRNA_proxy,partial_PS,0.28886,low_PS,0,2prime_OMe_pyrimidine_modified_siRNA_proxy|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_5,0.92575,inferred_from_paper,lineage_tracing_scRNAseq_WB_IF_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000760,OLIGO_0000760,ENGELBEEN_ALK4_MUSCLE_SIRNA_2023,2prime_F,low_or_no_PS,0.02472,low_PS,0,2prime_F|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_1,0.95507,inferred_from_paper,HPLC,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000761,OLIGO_0000761,KANDA_PCDHA11_AMNA_ASO_2024,AmNA,high_PS,1.0,high_PS,0,AmNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_17,0.96727,inferred_from_paper,AmNA_ASO_synthesis_HPLC_LCMS_qPCR_microarray_toxicology_generated_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000762,OLIGO_0000762,KIM_LARP6_HSC_FIBROSIS_DSI_RNA_2026,AmNA,partial_PS,0.2993,low_PS,0,AmNA|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_7,0.99531,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000763,OLIGO_0000763,QU_CPG_ODN_APAP_TLR9_IRG1_2025,LNA,partial_PS,0.08253,low_PS,0,LNA|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_2,0.94784,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000764,OLIGO_0000764,SUBRAMANIAN_RNAI_RHEOSTAT_AAV_TRANSGENE_2023,2prime_OMe,partial_PS,0.24104,low_PS,0,2prime_OMe|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_5,0.999,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000765,OLIGO_0000765,ARMISEN_AZD2693_PNPLA3_ASO_MASH_2025,mixed,partial_PS,0.17341,low_PS,1,mixed|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_5,0.98108,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000766,OLIGO_0000766,OOSTVEEN_ANGPTL3_LIVER_SAFETY_2023,2prime_OMe,partial_PS,0.13493,low_PS,1,2prime_OMe|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_3,0.94894,inferred_from_paper,mass_spectrometry,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000767,OLIGO_0000767,RO7239958_GERETTI_2025,LNA,high_PS,0.86609,high_PS,1,LNA|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_22,0.98936,inferred_from_paper,HPLC+LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000768,OLIGO_0000768,GOTFRID_PS_LNA_HIV_ASO_ACTIVITY_2026,unmodified,partial_PS,0.27107,low_PS,1,unmodified|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_6,0.91051,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000769,OLIGO_0000769,YAMAGUCHI_SCPBNA2_REDUCED_HEPATOTOX_2025,unmodified,partial_PS,0.63247,medium_PS,0,unmodified|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_13,0.999,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000770,OLIGO_0000770,KIM_LARP6_HSC_FIBROSIS_DSI_RNA_2026,2prime_MOE,partial_PS,0.55554,medium_PS,0,2prime_MOE|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_16,0.97604,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000771,OLIGO_0000771,MA_HSD17B13_ASO_FIBROSIS_MOUSE_2024,mixed,high_PS,0.86012,high_PS,1,mixed|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_12,0.97686,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000772,OLIGO_0000772,TERADA_BROTHERS_ASO_PNA_TOEHOLD_2023,mixed,high_PS,0.90023,high_PS,1,mixed|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_23,0.95124,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000773,OLIGO_0000773,OOSTVEEN_ANGPTL3_LIVER_SAFETY_2023,2prime_MOE,partial_PS,0.27828,low_PS,1,2prime_MOE|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_6,0.93789,inferred_from_paper,HPLC+LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000774,OLIGO_0000774,UMEZU_ORAL_MIR29A_LIVER_FIBROSIS_NA_2025,2prime_F,high_PS,0.90122,high_PS,0,2prime_F|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_26,0.97631,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000775,OLIGO_0000775,OLSON_CHOLANGIOCYTE_CHOLESTASIS_2025,2prime_MOE,partial_PS,0.57174,medium_PS,1,2prime_MOE|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_14,0.94806,literature_grounded_generated,not_reported_generated,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000776,OLIGO_0000776,KEATING_ASO_OBESITY_NAFLD_2022,2prime_OMe,partial_PS,0.09336,low_PS,0,2prime_OMe|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_2,0.999,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000777,OLIGO_0000777,DEBACKER_GALNAC_LIVER_DELIVERY_REVIEW_2020,cEt,partial_PS,0.51673,medium_PS,0,cEt|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_13,0.93862,literature_grounded_generated,GalNAc_ASGPR_liver_delivery_review_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000778,OLIGO_0000778,MEMO_OLIGOTOX_PHASE2_ALIGNMENT,LNA,partial_PS,0.24064,low_PS,1,LNA|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_5,0.98814,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000779,OLIGO_0000779,KANDA_PCDHA11_AMNA_ASO_2024,AmNA,high_PS,1.0,high_PS,0,AmNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_15,0.97023,inferred_from_paper,AmNA_ASO_synthesis_HPLC_LCMS_qPCR_microarray_toxicology_generated_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000780,OLIGO_0000780,MA_HSD17B13_ASO_FIBROSIS_MOUSE_2024,2prime_OMe,partial_PS,0.65728,medium_PS,0,2prime_OMe|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_13,0.91186,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000781,OLIGO_0000781,JANAS_GALNAC_RNAI_NONCLINICAL_SAFETY_2018,LNA,partial_PS,0.58274,medium_PS,0,LNA|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_9,0.94155,literature_grounded_generated,rat_monkey_repeat_dose_toxicology_platform_safety_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000782,OLIGO_0000782,HUANG_AGT_GALNAC_SIRNA_TOXICOLOGY_2025,LNA,partial_PS,0.54563,medium_PS,1,LNA|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_10,0.93576,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000783,OLIGO_0000783,WANG_PMEVL_SEV_SMALL_RNA_PCSK9_2026,not_applicable_sEV_payload_context,low_or_no_PS,0.0,low_PS,0,not_applicable_sEV_payload_context|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_0,0.99314,literature_grounded_generated,RT_qPCR_NTA_TEM_Western_RNase_protection_IVIS_ALT_AST_H_E_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000784,OLIGO_0000784,HJELMGREN_PS_ASO_DDR_2026,RNA_PS,high_PS,0.7,high_PS,0,RNA_PS|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_15,0.96651,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000785,OLIGO_0000785,HUANG_AGT_GALNAC_SIRNA_TOXICOLOGY_2025,2prime_MOE,high_PS,0.93289,high_PS,0,2prime_MOE|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_24,0.95508,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000786,OLIGO_0000786,YAMAGUCHI_SCPBNA2_REDUCED_HEPATOTOX_2025,2prime_F,partial_PS,0.24461,low_PS,1,2prime_F|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_5,0.95504,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000787,OLIGO_0000787,RAPIROSIRAN_SANYAL_2025,cEt,partial_PS,0.16725,low_PS,1,cEt|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_5,0.97397,inferred_from_paper,HPLC+LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000788,OLIGO_0000788,LIVER_SPHEROID_SCHOLTEN_2026,AmNA,high_PS,0.85525,high_PS,1,AmNA|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_24,0.97954,inferred_from_paper,mass_spectrometry,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000789,OLIGO_0000789,ZHAI_GALNAC_LNP_SIMKK4_LIVER_REGEN_2026,synthetic_siRNA_payload_proxy,low_or_no_PS,0.0,low_PS,1,synthetic_siRNA_payload_proxy|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_0,0.86896,inferred_from_paper,MicroCT_H_E_Ki67_TUNEL_biochemistry_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000790,OLIGO_0000790,TERADA_BROTHERS_ASO_PNA_TOEHOLD_2023,cEt,partial_PS,0.56676,medium_PS,0,cEt|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_10,0.98961,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000791,OLIGO_0000791,JANAS_GALNAC_SIRNA_OFFTARGET_RAT_HEPATOTOX_2018,AmNA,high_PS,0.67446,high_PS,0,AmNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_10,0.95926,literature_grounded_generated,not_reported_generated,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000792,OLIGO_0000792,ABULHUSN_HSD17B13_PROTECTIVE_VARIANT_2018,cEt,partial_PS,0.05045,low_PS,0,cEt|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_1,0.99454,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000793,OLIGO_0000793,HAGEDORN_LNA_HEPATOTOX_RF_2013,LNA,high_PS,1.0,high_PS,0,LNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_12,0.89956,inferred_from_paper,ion_exchange_HPLC_LC_MS_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000794,OLIGO_0000794,BOSCO_INCLISIRAN_FH_REALWORLD_2025,unmodified,partial_PS,0.17711,low_PS,0,unmodified|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_5,0.9816,literature_grounded_generated,real_world_six_month_lipid_PWV_ALT_AST_CPK_monitoring_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000795,OLIGO_0000795,PNPLA3_ROMEO_VALENTI_2025,2prime_MOE,partial_PS,0.12259,low_PS,1,2prime_MOE|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_3,0.94872,inferred_from_paper,HPLC,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000796,OLIGO_0000796,MA_HSD17B13_ASO_FIBROSIS_MOUSE_2024,AmNA,high_PS,0.69079,high_PS,1,AmNA|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_13,0.99217,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000797,OLIGO_0000797,ABULHUSN_HSD17B13_PROTECTIVE_VARIANT_2018,2prime_F,partial_PS,0.16737,low_PS,0,2prime_F|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_4,0.95408,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000798,OLIGO_0000798,JANAS_GALNAC_RNAI_NONCLINICAL_SAFETY_2018,LNA,partial_PS,0.20476,low_PS,0,LNA|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_4,0.96921,literature_grounded_generated,rat_monkey_repeat_dose_toxicology_platform_safety_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000799,OLIGO_0000799,SUN_HCC_RNA_NANOPARTICLE_MULTITARGET_2026,2prime_OMe,partial_PS,0.0811,low_PS,0,2prime_OMe|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_2,0.999,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000800,OLIGO_0000800,AGARWAL_GALNAC_SIRNA_OFFTARGET_2025,AmNA,partial_PS,0.12982,low_PS,1,AmNA|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_3,0.99038,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000801,OLIGO_0000801,XIE_FBLL1_HCC_SPATIAL_MULTIOMICS_2026,mixed,low_or_no_PS,0.01947,low_PS,0,mixed|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_0,0.99701,inferred_from_paper,qRT_PCR_CCK8_colony_formation_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000802,OLIGO_0000802,GANE_VIR2218_ALNHBV_HBV_RNAI_2023,mixed_ESCplus_GNA_seed,high_PS,0.77796,high_PS,1,mixed_ESCplus_GNA_seed|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_12,0.96121,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000803,OLIGO_0000803,MOHAMED_NANOPARTICLE_HEPATITIS_2026,mixed,high_PS,0.6732,high_PS,1,mixed|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_16,0.97888,inferred_from_paper,LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000804,OLIGO_0000804,YAMAGUCHI_SCPBNA2_REDUCED_HEPATOTOX_2025,2prime_MOE,partial_PS,0.08488,low_PS,0,2prime_MOE|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_2,0.96078,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000805,OLIGO_0000805,XIE_FBLL1_HCC_SPATIAL_MULTIOMICS_2026,mixed,partial_PS,0.05279,low_PS,0,mixed|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_1,0.99655,inferred_from_paper,RNAseq_Western_blot_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000806,OLIGO_0000806,PNPLA3_ROMEO_VALENTI_2025,mixed,partial_PS,0.17775,low_PS,1,mixed|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_4,0.99186,inferred_from_paper,HPLC+LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000807,OLIGO_0000807,RAPIROSIRAN_SANYAL_2025,AmNA,partial_PS,0.66044,medium_PS,0,AmNA|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_17,0.9202,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000808,OLIGO_0000808,ANDERSSON_PRECLINICAL_OLIGO_SAFETY_2022,LNA,partial_PS,0.47897,medium_PS,1,LNA|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_11,0.98494,literature_grounded_generated,preclinical_safety_screening_cascade_ALT_AST_kidney_complement_platelet_offtarget_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000809,OLIGO_0000809,PRAKASH_APOC3_LONG_ACTING_GALNAC_SIRNA_2025,LNA,low_or_no_PS,0.04403,low_PS,0,LNA|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_1,0.999,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000810,OLIGO_0000810,DEBACKER_GALNAC_LIVER_DELIVERY_REVIEW_2020,2prime_F,partial_PS,0.27674,low_PS,1,2prime_F|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_6,0.9703,literature_grounded_generated,GalNAc_ASGPR_liver_delivery_review_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000811,OLIGO_0000811,GOTFRID_PS_LNA_HIV_ASO_ACTIVITY_2026,LNA,high_PS,0.94421,high_PS,0,LNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_13,0.98413,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000812,OLIGO_0000812,LIVER_SPHEROID_SCHOLTEN_2026,2prime_OMe,partial_PS,0.64571,medium_PS,1,2prime_OMe|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_11,0.99689,inferred_from_paper,LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000813,OLIGO_0000813,OOSTVEEN_ANGPTL3_LIVER_SAFETY_2023,2prime_MOE,partial_PS,0.23857,low_PS,1,2prime_MOE|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_5,0.96884,inferred_from_paper,HPLC+LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000814,OLIGO_0000814,DEBACKER_GALNAC_LIVER_DELIVERY_REVIEW_2020,2prime_F,partial_PS,0.16703,low_PS,1,2prime_F|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_4,0.95018,literature_grounded_generated,GalNAc_ASGPR_liver_delivery_review_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000815,OLIGO_0000815,YAMAGUCHI_SCPBNA2_REDUCED_HEPATOTOX_2025,mixed,low_or_no_PS,0.04629,low_PS,1,mixed|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_1,0.93663,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000816,OLIGO_0000816,RAPIROSIRAN_SANYAL_2025,unmodified,partial_PS,0.06066,low_PS,1,unmodified|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_1,0.97368,inferred_from_paper,HPLC+LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000817,OLIGO_0000817,RAPIROSIRAN_SANYAL_2025,AmNA,partial_PS,0.08955,low_PS,1,AmNA|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_2,0.94183,inferred_from_paper,mass_spectrometry,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000818,OLIGO_0000818,KANDA_PCDHA11_AMNA_ASO_2024,AmNA,high_PS,1.0,high_PS,0,AmNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_17,0.98055,inferred_from_paper,AmNA_ASO_synthesis_HPLC_LCMS_qPCR_microarray_toxicology_generated_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000819,OLIGO_0000819,ARMISEN_AZD2693_PNPLA3_ASO_MASH_2025,AmNA,high_PS,0.76007,high_PS,1,AmNA|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_19,0.95705,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000820,OLIGO_0000820,RO7239958_GERETTI_2025,LNA,high_PS,0.92495,high_PS,1,LNA|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_24,0.93171,inferred_from_paper,HPLC,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000821,OLIGO_0000821,ABULHUSN_HSD17B13_PROTECTIVE_VARIANT_2018,LNA,partial_PS,0.52824,medium_PS,1,LNA|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_12,0.95032,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000822,OLIGO_0000822,EGLI_MANOHARAN_APPROVED_OLIGO_CHEMISTRY_2023,2prime_F,partial_PS,0.12301,low_PS,0,2prime_F|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_3,0.88456,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000823,OLIGO_0000823,RAPIROSIRAN_SANYAL_2025,mixed,low_or_no_PS,0.04498,low_PS,1,mixed|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_1,0.98194,inferred_from_paper,HPLC+LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000824,OLIGO_0000824,AGARWAL_GALNAC_SIRNA_OFFTARGET_2025,unmodified,partial_PS,0.27743,low_PS,0,unmodified|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_6,0.99075,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000825,OLIGO_0000825,KIM_LARP6_HSC_FIBROSIS_DSI_RNA_2026,cEt,high_PS,0.96222,high_PS,0,cEt|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_16,0.96255,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000826,OLIGO_0000826,YAMAGUCHI_SCPBNA2_REDUCED_HEPATOTOX_2025,2prime_MOE,partial_PS,0.39491,medium_PS,0,2prime_MOE|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_9,0.95081,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000827,OLIGO_0000827,LIVER_SPHEROID_SCHOLTEN_2026,2prime_F,high_PS,0.89265,high_PS,1,2prime_F|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_21,0.999,inferred_from_paper,mass_spectrometry,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000828,OLIGO_0000828,KEATING_ASO_OBESITY_NAFLD_2022,2prime_F,low_or_no_PS,0.02341,low_PS,0,2prime_F|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_0,0.98258,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000829,OLIGO_0000829,GANE_VIR2218_ALNHBV_HBV_RNAI_2023,mixed_ESCplus_GNA_seed,partial_PS,0.14265,low_PS,1,mixed_ESCplus_GNA_seed|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_3,0.999,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000830,OLIGO_0000830,SOUSA_HDO_MULTIFUNCTIONAL_HELA_2022,2prime_F,partial_PS,0.32054,low_PS,1,2prime_F|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_7,0.96519,literature_grounded_generated,IFN_alpha_disulfidptosis_context_nonreducing_WB_NADPH_Factin_siRNA_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000831,OLIGO_0000831,HAUPTMANN_SIRNA_BULGES_GALNAC_2022,2OMe_2F_alternating,partial_PS,0.09144,low_PS,0,2OMe_2F_alternating|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_2,0.92874,inferred_from_paper,qRT_PCR_ELISA_reporter_melting_LCMS_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000832,OLIGO_0000832,HUANG_AGT_GALNAC_SIRNA_TOXICOLOGY_2025,mixed,high_PS,0.87503,high_PS,1,mixed|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_18,0.96904,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000833,OLIGO_0000833,JIANG_LNP_CRISPR_HAO1_PH1_2025,AmNA,partial_PS,0.41485,medium_PS,0,AmNA|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_10,0.96471,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000834,OLIGO_0000834,ARMISEN_AZD2693_PNPLA3_ASO_MASH_2025,2prime_F,partial_PS,0.53824,medium_PS,0,2prime_F|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_12,0.99341,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000835,OLIGO_0000835,LIVER_SPHEROID_SCHOLTEN_2026,LNA,high_PS,0.91661,high_PS,1,LNA|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_13,0.96075,inferred_from_paper,HPLC,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000836,OLIGO_0000836,WANG_PMEVL_SEV_SMALL_RNA_PCSK9_2026,not_applicable_sEV_payload_context,low_or_no_PS,0.0,low_PS,0,not_applicable_sEV_payload_context|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_0,0.96274,literature_grounded_generated,RT_qPCR_NTA_TEM_Western_RNase_protection_IVIS_ALT_AST_H_E_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000837,OLIGO_0000837,KIM_NANP_LIPID_LIVER_TARGETING_2026,2prime_F,partial_PS,0.33288,low_PS,1,2prime_F|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_6,0.96415,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000838,OLIGO_0000838,PNPLA3_ROMEO_VALENTI_2025,mixed,partial_PS,0.58,medium_PS,1,mixed|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_13,0.94306,inferred_from_paper,HPLC,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000839,OLIGO_0000839,HUANG_AGT_GALNAC_SIRNA_TOXICOLOGY_2025,mixed,partial_PS,0.19474,low_PS,1,mixed|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_4,0.98965,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000840,OLIGO_0000840,KANDA_PCDHA11_AMNA_ASO_2024,AmNA,high_PS,1.0,high_PS,0,AmNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_17,0.98695,inferred_from_paper,AmNA_ASO_synthesis_HPLC_LCMS_qPCR_microarray_toxicology_generated_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000841,OLIGO_0000841,DEBACKER_GALNAC_LIVER_DELIVERY_REVIEW_2020,AmNA,partial_PS,0.27507,low_PS,0,AmNA|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_7,0.96353,literature_grounded_generated,GalNAc_ASGPR_liver_delivery_review_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000842,OLIGO_0000842,JIANG_AOC_FREE_ASO_PAYLOAD_HYBRIDIZATION_LCMS_2024,mixed,partial_PS,0.05968,low_PS,0,mixed|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_1,0.98278,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000843,OLIGO_0000843,SUBRAMANIAN_RNAI_RHEOSTAT_AAV_TRANSGENE_2023,mixed,partial_PS,0.61872,medium_PS,0,mixed|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_16,0.98044,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000844,OLIGO_0000844,KIM_MILASEN_CUSTOM_ASO_2019,2prime_MOE,partial_PS,0.55391,medium_PS,1,2prime_MOE|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_13,0.98184,inferred_from_paper,mass_spectrometry,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000845,OLIGO_0000845,XIE_FBLL1_HCC_SPATIAL_MULTIOMICS_2026,unmodified_or_research_siRNA_proxy,low_or_no_PS,2e-05,low_PS,0,unmodified_or_research_siRNA_proxy|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_0,0.95832,inferred_from_paper,qRT_PCR_CCK8_colony_formation_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000846,OLIGO_0000846,QU_CPG_ODN_APAP_TLR9_IRG1_2025,cEt,high_PS,0.79352,high_PS,0,cEt|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_22,0.96387,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000847,OLIGO_0000847,JANAS_GALNAC_RNAI_NONCLINICAL_SAFETY_2018,mixed,high_PS,0.69806,high_PS,0,mixed|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_13,0.94326,literature_grounded_generated,rat_monkey_repeat_dose_toxicology_platform_safety_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000848,OLIGO_0000848,MA_HSD17B13_ASO_FIBROSIS_MOUSE_2024,LNA,high_PS,0.74174,high_PS,1,LNA|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_16,0.96771,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000849,OLIGO_0000849,QU_CPG_ODN_APAP_TLR9_IRG1_2025,unmodified,partial_PS,0.21428,low_PS,1,unmodified|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_5,0.97592,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000850,OLIGO_0000850,KIM_MILASEN_CUSTOM_ASO_2019,2prime_MOE,high_PS,1.0,high_PS,0,2prime_MOE|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_21,0.94301,inferred_from_paper,HPLC+LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000851,OLIGO_0000851,ZHAI_GALNAC_LNP_SIMKK4_LIVER_REGEN_2026,synthetic_siRNA_payload_proxy,low_or_no_PS,0.0,low_PS,1,synthetic_siRNA_payload_proxy|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_0,0.8718,inferred_from_paper,qRT_PCR_flow_CLSM_hemolysis_live_dead_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000852,OLIGO_0000852,BOSCO_INCLISIRAN_FH_REALWORLD_2025,cEt,partial_PS,0.12668,low_PS,1,cEt|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_3,0.94804,literature_grounded_generated,real_world_six_month_lipid_PWV_ALT_AST_CPK_monitoring_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000853,OLIGO_0000853,BI_IFNA_DISULFIDPTOSIS_HCC_2026,2prime_MOE,partial_PS,0.06032,low_PS,0,2prime_MOE|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_2,0.999,literature_grounded_generated,IFN_alpha_disulfidptosis_context_nonreducing_WB_NADPH_Factin_siRNA_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000854,OLIGO_0000854,MENG_HYBRID_RNA_LNP_HCC_2025,2prime_OMe,partial_PS,0.25222,low_PS,0,2prime_OMe|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_6,0.94735,inferred_from_paper,HPLC,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000855,OLIGO_0000855,TERADA_BROTHERS_ASO_PNA_TOEHOLD_2023,2prime_F,partial_PS,0.45542,medium_PS,1,2prime_F|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_10,0.94499,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000856,OLIGO_0000856,PRAKASH_APOC3_LONG_ACTING_GALNAC_SIRNA_2025,unmodified,partial_PS,0.22088,low_PS,0,unmodified|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_4,0.95218,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000857,OLIGO_0000857,MEMO_OLIGOTOX_PHASE2_ALIGNMENT,AmNA,low_or_no_PS,0.0402,low_PS,1,AmNA|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_1,0.96507,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000858,OLIGO_0000858,DU_MALAT1_HBV_HCC_ASO_2025,gapmer_like_ASO_proxy,high_PS,0.704,high_PS,0,gapmer_like_ASO_proxy|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_13,0.93427,inferred_from_paper,ASO_xenograft_orthotopic_BLI_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000859,OLIGO_0000859,YAMAGUCHI_SCPBNA2_REDUCED_HEPATOTOX_2025,LNA,high_PS,0.93608,high_PS,1,LNA|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_25,0.97319,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000860,OLIGO_0000860,KIM_LARP6_HSC_FIBROSIS_DSI_RNA_2026,2prime_OMe,low_or_no_PS,0.0072,low_PS,1,2prime_OMe|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_0,0.93828,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000861,OLIGO_0000861,EGLI_MANOHARAN_APPROVED_OLIGO_CHEMISTRY_2023,unmodified,partial_PS,0.30988,low_PS,0,unmodified|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_6,0.98019,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000862,OLIGO_0000862,XIE_FBLL1_HCC_SPATIAL_MULTIOMICS_2026,mixed,low_or_no_PS,6e-05,low_PS,0,mixed|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_0,0.98005,inferred_from_paper,xenograft_Ki67_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000863,OLIGO_0000863,ABULHUSN_HSD17B13_PROTECTIVE_VARIANT_2018,LNA,high_PS,0.77371,high_PS,1,LNA|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_22,0.97919,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000864,OLIGO_0000864,HUANG_AGT_GALNAC_SIRNA_TOXICOLOGY_2025,unmodified,partial_PS,0.26616,low_PS,1,unmodified|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_5,0.97251,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000865,OLIGO_0000865,ANDERSSON_PRECLINICAL_OLIGO_SAFETY_2022,LNA,partial_PS,0.09763,low_PS,0,LNA|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_2,0.89614,literature_grounded_generated,preclinical_safety_screening_cascade_ALT_AST_kidney_complement_platelet_offtarget_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000866,OLIGO_0000866,LIVER_SPHEROID_SCHOLTEN_2026,2prime_F,partial_PS,0.27132,low_PS,1,2prime_F|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_7,0.99591,inferred_from_paper,not_reported_generated,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000867,OLIGO_0000867,ABULHUSN_HSD17B13_PROTECTIVE_VARIANT_2018,LNA,partial_PS,0.62273,medium_PS,1,LNA|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_17,0.97162,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000868,OLIGO_0000868,LU_GT_MULTI_SIRNA_HCC_2025,2prime_F,partial_PS,0.57656,medium_PS,0,2prime_F|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_9,0.96013,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000869,OLIGO_0000869,KEATING_ASO_OBESITY_NAFLD_2022,2prime_MOE,high_PS,0.89412,high_PS,0,2prime_MOE|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_20,0.999,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000870,OLIGO_0000870,DU_MALAT1_HBV_HCC_ASO_2025,ASO_proxy,high_PS,0.76844,high_PS,0,ASO_proxy|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_15,0.92976,inferred_from_paper,RNA_pulldown_luciferase_RNA_decay_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000871,OLIGO_0000871,QU_CPG_ODN_APAP_TLR9_IRG1_2025,2prime_F,partial_PS,0.28293,low_PS,1,2prime_F|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_6,0.97753,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000872,OLIGO_0000872,RAPIROSIRAN_SANYAL_2025,cEt,partial_PS,0.5973,medium_PS,0,cEt|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_14,0.98633,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000873,OLIGO_0000873,KEATING_ASO_OBESITY_NAFLD_2022,2prime_OMe,high_PS,0.79666,high_PS,0,2prime_OMe|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_13,0.95452,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000874,OLIGO_0000874,TERADA_BROTHERS_ASO_PNA_TOEHOLD_2023,AmNA,partial_PS,0.21392,low_PS,0,AmNA|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_4,0.925,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000875,OLIGO_0000875,RAPIROSIRAN_SANYAL_2025,mixed,partial_PS,0.26072,low_PS,1,mixed|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_7,0.97234,inferred_from_paper,mass_spectrometry,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000876,OLIGO_0000876,PRAKASH_APOC3_LONG_ACTING_GALNAC_SIRNA_2025,cEt,partial_PS,0.36285,medium_PS,1,cEt|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_7,0.98622,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000877,OLIGO_0000877,HAGEDORN_LNA_HEPATOTOX_RF_2013,LNA,high_PS,0.79347,high_PS,0,LNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_10,0.93767,inferred_from_paper,ion_exchange_HPLC_LC_MS_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000878,OLIGO_0000878,SUN_HCC_RNA_NANOPARTICLE_MULTITARGET_2026,LNA,partial_PS,0.16557,low_PS,1,LNA|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_3,0.96155,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000879,OLIGO_0000879,KIM_NANP_LIPID_LIVER_TARGETING_2026,2prime_MOE,partial_PS,0.35314,medium_PS,0,2prime_MOE|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_8,0.99677,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000880,OLIGO_0000880,PRAKASH_APOC3_LONG_ACTING_GALNAC_SIRNA_2025,2prime_OMe,high_PS,0.94461,high_PS,0,2prime_OMe|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_14,0.92185,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000881,OLIGO_0000881,KANDA_PCDHA11_AMNA_ASO_2024,AmNA,high_PS,1.0,high_PS,0,AmNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_15,0.99532,inferred_from_paper,AmNA_ASO_synthesis_HPLC_LCMS_qPCR_microarray_toxicology_generated_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000882,OLIGO_0000882,KANDA_PCDHA11_AMNA_ASO_2024,AmNA,high_PS,1.0,high_PS,0,AmNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_17,0.98327,inferred_from_paper,AmNA_ASO_synthesis_HPLC_LCMS_qPCR_microarray_toxicology_generated_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000883,OLIGO_0000883,JANAS_GALNAC_RNAI_NONCLINICAL_SAFETY_2018,LNA,high_PS,0.92395,high_PS,1,LNA|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_18,0.95539,literature_grounded_generated,rat_monkey_repeat_dose_toxicology_platform_safety_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000884,OLIGO_0000884,PAN_CD133_MASLD_HCC_SIRNA_2025,mixed_siRNA_stabilization_proxy,partial_PS,0.18188,low_PS,0,mixed_siRNA_stabilization_proxy|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_4,0.95673,inferred_from_paper,VNP_siRNA_sorafenib_lenvatinib_response_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000885,OLIGO_0000885,LI_FXR_JNK_G0S2_TRIPTOLIDE_HEPATOTOXICITY_2025,LNA,high_PS,0.97747,high_PS,1,LNA|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_22,0.97669,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000886,OLIGO_0000886,EGLI_MANOHARAN_APPROVED_OLIGO_CHEMISTRY_2023,LNA,partial_PS,0.35047,medium_PS,0,LNA|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_9,0.98848,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000887,OLIGO_0000887,OOSTVEEN_ANGPTL3_LIVER_SAFETY_2023,mixed,partial_PS,0.21239,low_PS,0,mixed|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_5,0.97991,inferred_from_paper,mass_spectrometry,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000888,OLIGO_0000888,YAMAGUCHI_SCPBNA2_REDUCED_HEPATOTOX_2025,LNA,high_PS,0.84035,high_PS,1,LNA|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_17,0.94644,literature_grounded_generated,not_reported_generated,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000889,OLIGO_0000889,KIM_MILASEN_CUSTOM_ASO_2019,2prime_MOE,high_PS,1.0,high_PS,0,2prime_MOE|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_21,0.999,inferred_from_paper,HPLC,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000890,OLIGO_0000890,OOSTVEEN_ANGPTL3_LIVER_SAFETY_2023,LNA,partial_PS,0.50364,medium_PS,1,LNA|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_11,0.9433,inferred_from_paper,HPLC+LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000891,OLIGO_0000891,OLSON_CHOLANGIOCYTE_CHOLESTASIS_2025,mixed,partial_PS,0.32562,low_PS,1,mixed|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_8,0.97719,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000892,OLIGO_0000892,ZHAI_GALNAC_LNP_SIMKK4_LIVER_REGEN_2026,synthetic_siRNA_payload_proxy,low_or_no_PS,0.0,low_PS,1,synthetic_siRNA_payload_proxy|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_0,0.88867,inferred_from_paper,MicroCT_H_E_Ki67_TUNEL_biochemistry_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000893,OLIGO_0000893,GOTFRID_PS_LNA_HIV_ASO_ACTIVITY_2026,LNA,partial_PS,0.44527,medium_PS,1,LNA|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_10,0.96339,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000894,OLIGO_0000894,ARMISEN_AZD2693_PNPLA3_ASO_MASH_2025,LNA,high_PS,0.82181,high_PS,1,LNA|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_21,0.94794,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000895,OLIGO_0000895,KANDA_PCDHA11_AMNA_ASO_2024,AmNA,high_PS,1.0,high_PS,0,AmNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_17,0.98682,inferred_from_paper,AmNA_ASO_synthesis_HPLC_LCMS_qPCR_microarray_toxicology_generated_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000896,OLIGO_0000896,WAN_PUM1_EXOSOMES_MASLD_HSC_FIBROSIS_2025,LNA,high_PS,0.80017,high_PS,1,LNA|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_18,0.9952,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000897,OLIGO_0000897,DUDZICZ_ZILEBESIRAN_HTN_REVIEW_2025,mixed,partial_PS,0.06035,low_PS,1,mixed|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_2,0.93368,inferred_from_paper,HPLC,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000898,OLIGO_0000898,JANAS_GALNAC_SIRNA_OFFTARGET_RAT_HEPATOTOX_2018,mixed,high_PS,0.85405,high_PS,0,mixed|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_15,0.999,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000899,OLIGO_0000899,KANDA_PCDHA11_AMNA_ASO_2024,AmNA,high_PS,1.0,high_PS,0,AmNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_19,0.9849,inferred_from_paper,AmNA_ASO_synthesis_HPLC_LCMS_qPCR_microarray_toxicology_generated_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000900,OLIGO_0000900,KANDA_PCDHA11_AMNA_ASO_2024,AmNA,high_PS,1.0,high_PS,0,AmNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_17,0.99726,inferred_from_paper,AmNA_ASO_synthesis_HPLC_LCMS_qPCR_microarray_toxicology_generated_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000901,OLIGO_0000901,PARK_ERBB2_APTAMER_PET_PK_2023,2prime_MOE,partial_PS,0.201,low_PS,1,2prime_MOE|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_4,0.98343,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000902,OLIGO_0000902,KIM_NANP_LIPID_LIVER_TARGETING_2026,2prime_OMe,partial_PS,0.14218,low_PS,0,2prime_OMe|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_3,0.95673,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000903,OLIGO_0000903,CHEN_OVARIAN_MTTP_APOB_MIPOMERSEN_2025,2prime_MOE,partial_PS,0.22,low_PS,0,2prime_MOE|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_6,0.999,inferred_from_paper,LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000904,OLIGO_0000904,LIVER_SPHEROID_SCHOLTEN_2026,AmNA,partial_PS,0.51852,medium_PS,1,AmNA|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_12,0.98145,inferred_from_paper,LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000905,OLIGO_0000905,ARMISEN_AZD2693_PNPLA3_ASO_MASH_2025,unmodified,partial_PS,0.17473,low_PS,1,unmodified|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_5,0.999,literature_grounded_generated,IFN_alpha_disulfidptosis_context_nonreducing_WB_NADPH_Factin_siRNA_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000906,OLIGO_0000906,ARMISEN_AZD2693_PNPLA3_ASO_MASH_2025,cEt,high_PS,0.91357,high_PS,0,cEt|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_18,0.9083,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000907,OLIGO_0000907,SUN_HCC_RNA_NANOPARTICLE_MULTITARGET_2026,mixed,partial_PS,0.20395,low_PS,1,mixed|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_5,0.96812,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000908,OLIGO_0000908,RO7239958_GERETTI_2025,2prime_MOE,high_PS,0.77641,high_PS,0,2prime_MOE|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_19,0.98883,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000909,OLIGO_0000909,MA_HSD17B13_ASO_FIBROSIS_MOUSE_2024,cEt,partial_PS,0.26698,low_PS,0,cEt|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_6,0.95915,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000910,OLIGO_0000910,AGARWAL_GALNAC_SIRNA_OFFTARGET_2025,LNA,partial_PS,0.60653,medium_PS,1,LNA|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_9,0.95431,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000911,OLIGO_0000911,KIM_NANP_LIPID_LIVER_TARGETING_2026,unmodified,partial_PS,0.17981,low_PS,1,unmodified|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_4,0.96278,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000912,OLIGO_0000912,OOSTVEEN_ANGPTL3_LIVER_SAFETY_2023,LNA,partial_PS,0.43428,medium_PS,1,LNA|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_12,0.98989,inferred_from_paper,mass_spectrometry,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000913,OLIGO_0000913,LIVER_SPHEROID_SCHOLTEN_2026,mixed,partial_PS,0.42805,medium_PS,1,mixed|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_9,0.9863,inferred_from_paper,HPLC,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000914,OLIGO_0000914,BUREL_GAPMER_RNASEH1_LONG_PREMRNA_HEPATOTOX_2016,2prime_OMe,partial_PS,0.35298,medium_PS,0,2prime_OMe|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_8,0.98772,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000915,OLIGO_0000915,JANAS_GALNAC_SIRNA_OFFTARGET_RAT_HEPATOTOX_2018,cEt,partial_PS,0.46066,medium_PS,1,cEt|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_10,0.96617,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000916,OLIGO_0000916,KANDA_PCDHA11_AMNA_ASO_2024,AmNA,high_PS,1.0,high_PS,0,AmNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_15,0.98756,inferred_from_paper,AmNA_ASO_synthesis_HPLC_LCMS_qPCR_microarray_toxicology_generated_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000917,OLIGO_0000917,DHARA_LNA_PHOSPHOTHIOTRIESTER_SSO_CLICK_2025,AmNA,partial_PS,0.13259,low_PS,0,AmNA|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_3,0.96936,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000918,OLIGO_0000918,MEKONNEN_MYC_ASIRNA_DCA_TNBC_2025,2prime_F,partial_PS,0.54153,medium_PS,1,2prime_F|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_12,0.96354,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000919,OLIGO_0000919,TERADA_BROTHERS_ASO_PNA_TOEHOLD_2023,2prime_MOE,partial_PS,0.09003,low_PS,0,2prime_MOE|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_2,0.96637,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000920,OLIGO_0000920,RO7239958_GERETTI_2025,2prime_OMe,partial_PS,0.31758,low_PS,0,2prime_OMe|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_7,0.91796,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000921,OLIGO_0000921,WANG_PMEVL_SEV_SMALL_RNA_PCSK9_2026,not_applicable_sEV_payload_context,low_or_no_PS,0.0,low_PS,0,not_applicable_sEV_payload_context|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_0,0.97474,literature_grounded_generated,RT_qPCR_NTA_TEM_Western_RNase_protection_IVIS_ALT_AST_H_E_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000922,OLIGO_0000922,RO7239958_GERETTI_2025,cEt,partial_PS,0.30162,low_PS,1,cEt|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_6,0.96841,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000923,OLIGO_0000923,CROOKE_RNA_TARGETED_THERAPEUTICS_2018,unmodified,partial_PS,0.28384,low_PS,0,unmodified|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_7,0.96421,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000924,OLIGO_0000924,OLIVER_HILL_MODEL_SELECTION_NAT_2026,2prime_F,high_PS,0.93807,high_PS,0,2prime_F|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_14,0.99894,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000925,OLIGO_0000925,HAGEDORN_LNA_HEPATOTOX_RF_2013,LNA,high_PS,0.8809,high_PS,0,LNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_12,0.92065,inferred_from_paper,ion_exchange_HPLC_LC_MS_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000926,OLIGO_0000926,MOHAMED_NANOPARTICLE_HEPATITIS_2026,cEt,partial_PS,0.47387,medium_PS,0,cEt|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_9,0.92835,inferred_from_paper,mass_spectrometry,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000927,OLIGO_0000927,WANG_PMEVL_SEV_SMALL_RNA_PCSK9_2026,not_applicable_sEV_payload_context,low_or_no_PS,0.0,low_PS,0,not_applicable_sEV_payload_context|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_0,0.95646,literature_grounded_generated,RT_qPCR_NTA_TEM_Western_RNase_protection_IVIS_ALT_AST_H_E_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000928,OLIGO_0000928,HUANG_GALNAC_RBC_EV_LIVER_DISEASE_2025,ASO_anti_miR_proxy,partial_PS,0.2181,low_PS,1,ASO_anti_miR_proxy|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_4,0.88656,inferred_from_paper,Rab7_siRNA_PJ34_HCC_retention_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000929,OLIGO_0000929,HUANG_AGT_GALNAC_SIRNA_TOXICOLOGY_2025,unmodified,partial_PS,0.06118,low_PS,1,unmodified|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_1,0.9914,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000930,OLIGO_0000930,HUANG_AGT_GALNAC_SIRNA_TOXICOLOGY_2025,2prime_MOE,high_PS,0.70804,high_PS,0,2prime_MOE|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_11,0.94053,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000931,OLIGO_0000931,HAGEDORN_LNA_HEPATOTOX_RF_2013,LNA,high_PS,0.85328,high_PS,0,LNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_10,0.90253,inferred_from_paper,ion_exchange_HPLC_LC_MS_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000932,OLIGO_0000932,HUANG_AGT_GALNAC_SIRNA_TOXICOLOGY_2025,LNA,partial_PS,0.11213,low_PS,0,LNA|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_3,0.96828,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000933,OLIGO_0000933,MEKONNEN_MYC_ASIRNA_DCA_TNBC_2025,cEt,partial_PS,0.13321,low_PS,1,cEt|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_3,0.97909,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000934,OLIGO_0000934,CROOKE_RNA_TARGETED_THERAPEUTICS_2018,cEt,partial_PS,0.64343,medium_PS,0,cEt|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_16,0.93273,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000935,OLIGO_0000935,HJELMGREN_PS_ASO_DDR_2026,RNA_PS,high_PS,0.7,high_PS,0,RNA_PS|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_17,0.92889,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000936,OLIGO_0000936,KEATING_ASO_OBESITY_NAFLD_2022,unmodified,partial_PS,0.41833,medium_PS,1,unmodified|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_11,0.94769,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000937,OLIGO_0000937,BOSCO_INCLISIRAN_FH_REALWORLD_2025,unmodified,partial_PS,0.58219,medium_PS,0,unmodified|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_13,0.97184,literature_grounded_generated,real_world_six_month_lipid_PWV_ALT_AST_CPK_monitoring_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000938,OLIGO_0000938,BUREL_GAPMER_RNASEH1_LONG_PREMRNA_HEPATOTOX_2016,2prime_F,partial_PS,0.37741,medium_PS,0,2prime_F|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_7,0.92527,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000939,OLIGO_0000939,YAMAGUCHI_SCPBNA2_REDUCED_HEPATOTOX_2025,2prime_MOE,high_PS,0.84003,high_PS,0,2prime_MOE|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_15,0.94106,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000940,OLIGO_0000940,HUANG_AGT_GALNAC_SIRNA_TOXICOLOGY_2025,mixed,partial_PS,0.62796,medium_PS,0,mixed|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_14,0.96556,literature_grounded_generated,not_reported_generated,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000941,OLIGO_0000941,YAMAGUCHI_SCPBNA2_REDUCED_HEPATOTOX_2025,LNA,high_PS,0.89382,high_PS,0,LNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_24,0.95839,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000942,OLIGO_0000942,MEMO_OLIGOTOX_PHASE2_ALIGNMENT,2prime_MOE,partial_PS,0.17058,low_PS,1,2prime_MOE|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_4,0.98741,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000943,OLIGO_0000943,PRAKASH_APOC3_LONG_ACTING_GALNAC_SIRNA_2025,2prime_MOE,partial_PS,0.36275,medium_PS,0,2prime_MOE|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_8,0.97026,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000944,OLIGO_0000944,SCHLEGEL_ESCPLUS_SEED_PAIRING_GALNAC_SIRNA_2022,2prime_OMe,high_PS,0.84038,high_PS,1,2prime_OMe|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_19,0.9548,literature_grounded_generated,not_reported_generated,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000945,OLIGO_0000945,LIU_CYP2E1_LNP_APAP_AILI_2025,2prime_MOE,partial_PS,0.25977,low_PS,0,2prime_MOE|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_7,0.97217,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000946,OLIGO_0000946,KIM_LARP6_HSC_FIBROSIS_DSI_RNA_2026,2prime_OMe,partial_PS,0.15275,low_PS,0,2prime_OMe|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_3,0.93615,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000947,OLIGO_0000947,TERADA_BROTHERS_ASO_PNA_TOEHOLD_2023,AmNA,high_PS,0.7354,high_PS,0,AmNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_13,0.97411,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000948,OLIGO_0000948,HUANG_AGT_GALNAC_SIRNA_TOXICOLOGY_2025,cEt,partial_PS,0.33269,low_PS,0,cEt|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_8,0.999,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000949,OLIGO_0000949,RO7239958_GERETTI_2025,LNA,partial_PS,0.65697,medium_PS,1,LNA|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_11,0.95505,inferred_from_paper,not_reported_generated,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000950,OLIGO_0000950,SUN_HCC_RNA_NANOPARTICLE_MULTITARGET_2026,mixed,high_PS,0.85246,high_PS,1,mixed|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_14,0.97057,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000951,OLIGO_0000951,LIU_CYP2E1_LNP_APAP_AILI_2025,LNA,partial_PS,0.35742,medium_PS,1,LNA|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_8,0.97547,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000952,OLIGO_0000952,KANDA_PCDHA11_AMNA_ASO_2024,AmNA,high_PS,1.0,high_PS,0,AmNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_17,0.9788,inferred_from_paper,AmNA_ASO_synthesis_HPLC_LCMS_qPCR_microarray_toxicology_generated_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000953,OLIGO_0000953,BERGEN_DILIMAP_TOXPREDICTOR_DILI_2025,LNA,low_or_no_PS,0.01056,low_PS,0,LNA|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_0,0.92854,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000954,OLIGO_0000954,ALSHAER_FDA_TIDES_HARVEST_2025,2prime_MOE,partial_PS,0.31209,low_PS,0,2prime_MOE|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_7,0.94779,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000955,OLIGO_0000955,OLSON_CHOLANGIOCYTE_CHOLESTASIS_2025,AmNA,partial_PS,0.16722,low_PS,1,AmNA|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_4,0.97872,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000956,OLIGO_0000956,JANAS_GALNAC_SIRNA_OFFTARGET_RAT_HEPATOTOX_2018,2prime_F,low_or_no_PS,0.02755,low_PS,0,2prime_F|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_1,0.9736,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000957,OLIGO_0000957,BOSCO_INCLISIRAN_FH_REALWORLD_2025,cEt,high_PS,0.88833,high_PS,0,cEt|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_17,0.97929,literature_grounded_generated,real_world_six_month_lipid_PWV_ALT_AST_CPK_monitoring_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000958,OLIGO_0000958,CROOKE_RNA_TARGETED_THERAPEUTICS_2018,LNA,partial_PS,0.20329,low_PS,0,LNA|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_4,0.96396,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000959,OLIGO_0000959,MEMO_OLIGOTOX_PHASE2_ALIGNMENT,cEt,high_PS,0.71991,high_PS,0,cEt|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_14,0.9501,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000960,OLIGO_0000960,DUDZICZ_ZILEBESIRAN_HTN_REVIEW_2025,mixed,partial_PS,0.1428,low_PS,1,mixed|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_3,0.97953,inferred_from_paper,HPLC,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000961,OLIGO_0000961,ARMISEN_AZD2693_PNPLA3_ASO_MASH_2025,AmNA,partial_PS,0.4999,medium_PS,0,AmNA|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_9,0.9496,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000962,OLIGO_0000962,RAPIROSIRAN_SANYAL_2025,unmodified,low_or_no_PS,0.02341,low_PS,1,unmodified|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_1,0.93801,inferred_from_paper,HPLC+LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000963,OLIGO_0000963,MEMO_OLIGOTOX_PHASE2_ALIGNMENT,mixed,high_PS,0.98813,high_PS,1,mixed|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_28,0.92103,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000964,OLIGO_0000964,MOHAMED_NANOPARTICLE_HEPATITIS_2026,mixed,partial_PS,0.34675,medium_PS,0,mixed|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_10,0.999,inferred_from_paper,HPLC,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000965,OLIGO_0000965,KEATING_ASO_OBESITY_NAFLD_2022,cEt,partial_PS,0.27058,low_PS,0,cEt|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_5,0.92759,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000966,OLIGO_0000966,BOSCO_INCLISIRAN_FH_REALWORLD_2025,cEt,partial_PS,0.24643,low_PS,0,cEt|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_6,0.97289,literature_grounded_generated,real_world_six_month_lipid_PWV_ALT_AST_CPK_monitoring_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000967,OLIGO_0000967,PRAKASH_APOC3_LONG_ACTING_GALNAC_SIRNA_2025,mixed,partial_PS,0.14076,low_PS,1,mixed|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_3,0.98937,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000968,OLIGO_0000968,LIVER_SPHEROID_SCHOLTEN_2026,mixed,partial_PS,0.23225,low_PS,0,mixed|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_6,0.999,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000969,OLIGO_0000969,RAPIROSIRAN_SANYAL_2025,mixed,partial_PS,0.32221,low_PS,0,mixed|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_8,0.98914,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000970,OLIGO_0000970,PNPLA3_ROMEO_VALENTI_2025,mixed,partial_PS,0.2,low_PS,1,mixed|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_5,0.95523,inferred_from_paper,HPLC+LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000971,OLIGO_0000971,ANDERSSON_PRECLINICAL_OLIGO_SAFETY_2022,LNA,partial_PS,0.24342,low_PS,0,LNA|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_4,0.999,literature_grounded_generated,preclinical_safety_screening_cascade_ALT_AST_kidney_complement_platelet_offtarget_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000972,OLIGO_0000972,UMEZU_ORAL_MIR29A_LIVER_FIBROSIS_NA_2025,2prime_F,partial_PS,0.32039,low_PS,0,2prime_F|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_6,0.999,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000973,OLIGO_0000973,ANDERSSON_PRECLINICAL_OLIGO_SAFETY_2022,unmodified,partial_PS,0.30406,low_PS,0,unmodified|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_7,0.98841,literature_grounded_generated,preclinical_safety_screening_cascade_ALT_AST_kidney_complement_platelet_offtarget_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000974,OLIGO_0000974,EGLI_MANOHARAN_APPROVED_OLIGO_CHEMISTRY_2023,LNA,partial_PS,0.15281,low_PS,1,LNA|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_4,0.93082,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000975,OLIGO_0000975,RAPIROSIRAN_SANYAL_2025,2prime_F,partial_PS,0.25396,low_PS,1,2prime_F|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_6,0.9633,inferred_from_paper,LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000976,OLIGO_0000976,RAPIROSIRAN_SANYAL_2025,LNA,partial_PS,0.45911,medium_PS,1,LNA|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_10,0.999,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000977,OLIGO_0000977,RO7239958_GERETTI_2025,LNA,high_PS,0.92968,high_PS,1,LNA|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_24,0.94331,inferred_from_paper,mass_spectrometry,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000978,OLIGO_0000978,LIU_CYP2E1_LNP_APAP_AILI_2025,2prime_OMe,partial_PS,0.50824,medium_PS,0,2prime_OMe|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_14,0.94763,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000979,OLIGO_0000979,YAMAGUCHI_SCPBNA2_REDUCED_HEPATOTOX_2025,2prime_F,partial_PS,0.22535,low_PS,0,2prime_F|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_5,0.9227,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000980,OLIGO_0000980,PRAKASH_APOC3_LONG_ACTING_GALNAC_SIRNA_2025,LNA,high_PS,0.70521,high_PS,0,LNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_20,0.96309,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000981,OLIGO_0000981,MEKONNEN_MYC_ASIRNA_DCA_TNBC_2025,2prime_MOE,partial_PS,0.07015,low_PS,0,2prime_MOE|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_2,0.99875,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000982,OLIGO_0000982,JANAS_GALNAC_SIRNA_OFFTARGET_RAT_HEPATOTOX_2018,2prime_MOE,partial_PS,0.08181,low_PS,0,2prime_MOE|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_2,0.94392,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000983,OLIGO_0000983,BERGEN_DILIMAP_TOXPREDICTOR_DILI_2025,2prime_OMe,partial_PS,0.20092,low_PS,1,2prime_OMe|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_4,0.94681,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000984,OLIGO_0000984,AGARWAL_GALNAC_SIRNA_OFFTARGET_2025,cEt,partial_PS,0.6087,medium_PS,0,cEt|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_15,0.97469,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000985,OLIGO_0000985,HUANG_AGT_GALNAC_SIRNA_TOXICOLOGY_2025,2prime_OMe,high_PS,0.80896,high_PS,0,2prime_OMe|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_11,0.96563,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000986,OLIGO_0000986,ZHAI_GALNAC_LNP_SIMKK4_LIVER_REGEN_2026,synthetic_siRNA_payload_proxy,low_or_no_PS,0.0,low_PS,1,synthetic_siRNA_payload_proxy|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_0,0.94367,inferred_from_paper,Western_IF_p38_JNK_ATF2_ELK1_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000987,OLIGO_0000987,LIVER_SPHEROID_SCHOLTEN_2026,LNA,partial_PS,0.375,medium_PS,1,LNA|medium_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_9,0.95264,inferred_from_paper,HPLC+LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000988,OLIGO_0000988,MEKONNEN_MYC_ASIRNA_DCA_TNBC_2025,mixed,partial_PS,0.19994,low_PS,0,mixed|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_4,0.999,literature_grounded_generated,LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000989,OLIGO_0000989,KIM_NANP_LIPID_LIVER_TARGETING_2026,AmNA,partial_PS,0.39189,medium_PS,0,AmNA|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_10,0.97957,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000990,OLIGO_0000990,ENGELBEEN_ALK4_MUSCLE_SIRNA_2023,mixed,partial_PS,0.08026,low_PS,0,mixed|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_2,0.92892,inferred_from_paper,not_reported_generated,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000991,OLIGO_0000991,TERADA_BROTHERS_ASO_PNA_TOEHOLD_2023,AmNA,partial_PS,0.10798,low_PS,0,AmNA|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_3,0.999,literature_grounded_generated,HPLC,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000992,OLIGO_0000992,MOHAMED_NANOPARTICLE_HEPATITIS_2026,LNA,high_PS,0.75785,high_PS,0,LNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_14,0.95987,inferred_from_paper,HPLC+LC-MS,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000993,OLIGO_0000993,LI_FXR_JNK_G0S2_TRIPTOLIDE_HEPATOTOXICITY_2025,mixed,partial_PS,0.4602,medium_PS,0,mixed|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_12,0.94187,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000994,OLIGO_0000994,KIM_LARP6_HSC_FIBROSIS_DSI_RNA_2026,2prime_OMe,partial_PS,0.236,low_PS,1,2prime_OMe|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_6,0.95166,literature_grounded_generated,HPLC+LC-MS,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000995,OLIGO_0000995,LIU_CYP2E1_LNP_APAP_AILI_2025,LNA,high_PS,0.78536,high_PS,1,LNA|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_13,0.96647,literature_grounded_generated,not_reported_generated,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000996,OLIGO_0000996,ARMISEN_AZD2693_PNPLA3_ASO_MASH_2025,mixed,partial_PS,0.31168,low_PS,1,mixed|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_7,0.9741,literature_grounded_generated,mass_spectrometry,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000997,OLIGO_0000997,DEBACKER_GALNAC_LIVER_DELIVERY_REVIEW_2020,2prime_F,low_or_no_PS,0.02893,low_PS,0,2prime_F|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_1,0.90652,literature_grounded_generated,GalNAc_ASGPR_liver_delivery_review_generated_proxy,literature_grounded_generated,dbbun_generated,literature_grounded_generated
MOD_OLIGO_0000998,OLIGO_0000998,HAGEDORN_LNA_HEPATOTOX_RF_2013,LNA,high_PS,0.91754,high_PS,0,LNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_11,0.89585,inferred_from_paper,ion_exchange_HPLC_LC_MS_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_0000999,OLIGO_0000999,ZHAI_GALNAC_LNP_SIMKK4_LIVER_REGEN_2026,synthetic_siRNA_payload_proxy,low_or_no_PS,0.0,low_PS,1,synthetic_siRNA_payload_proxy|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_0,0.91923,inferred_from_paper,MTT_colony_Ki67_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_CTRL_POS_ALD_ACETALDEHYDE_ROS_MITOCHONDRIAL_STRESS,OLIGO_CTRL_POS_ALD_ACETALDEHYDE_ROS_MITOCHONDRIAL_STRESS,MA_FORMONONETIN_ALDH2_ALD_2025,2prime_OMe_2prime_F_mixed,low_or_no_PS,0.05,low_PS,0,2prime_OMe_2prime_F_mixed|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_1,0.95,literature_grounded_generated_control,literature_context_control,literature_grounded_generated_control,dbbun_generated,literature_grounded_generated_control
MOD_OLIGO_CTRL_NEG_FORMONONETIN_ALDH2_NRF2_HEPATOPROTECTION,OLIGO_CTRL_NEG_FORMONONETIN_ALDH2_NRF2_HEPATOPROTECTION,MA_FORMONONETIN_ALDH2_ALD_2025,2prime_OMe_2prime_F_mixed,low_or_no_PS,0.05,low_PS,0,2prime_OMe_2prime_F_mixed|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_1,0.95,literature_grounded_generated_control,literature_context_control,literature_grounded_generated_control,dbbun_generated,literature_grounded_generated_control
MOD_OLIGO_CTRL_CONTEXT_ALDH2_NRF2_SIRNA_LOSS_OF_RESCUE,OLIGO_CTRL_CONTEXT_ALDH2_NRF2_SIRNA_LOSS_OF_RESCUE,MA_FORMONONETIN_ALDH2_ALD_2025,2prime_OMe_2prime_F_mixed,low_or_no_PS,0.05,low_PS,0,2prime_OMe_2prime_F_mixed|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_1,0.95,literature_grounded_generated_control,literature_context_control,literature_grounded_generated_control,dbbun_generated,literature_grounded_generated_control
MOD_OLIGO_CTRL_NEG_HNP_SIHOXB7_LOW_HEPATIC_SIGNAL,OLIGO_CTRL_NEG_HNP_SIHOXB7_LOW_HEPATIC_SIGNAL,VALLE_HOXB7_HNP_TAMOXIFEN_BREAST_2024,2prime_OMe_2prime_F_mixed,low_or_no_PS,0.05,low_PS,0,2prime_OMe_2prime_F_mixed|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_1,0.95,literature_grounded_generated_control,literature_context_control,literature_grounded_generated_control,dbbun_generated,literature_grounded_generated_control
MOD_OLIGO_CTRL_CONTEXT_HOXB7_SIRNA_TAMOXIFEN_COTREATMENT,OLIGO_CTRL_CONTEXT_HOXB7_SIRNA_TAMOXIFEN_COTREATMENT,VALLE_HOXB7_HNP_TAMOXIFEN_BREAST_2024,2prime_OMe_2prime_F_mixed,low_or_no_PS,0.05,low_PS,0,2prime_OMe_2prime_F_mixed|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_1,0.95,literature_grounded_generated_control,literature_context_control,literature_grounded_generated_control,dbbun_generated,literature_grounded_generated_control
MOD_OLIGO_CTRL_CONTEXT_HNP_CALCIUM_PHOSPHATE_ENDOSOMAL_ESCAPE,OLIGO_CTRL_CONTEXT_HNP_CALCIUM_PHOSPHATE_ENDOSOMAL_ESCAPE,VALLE_HOXB7_HNP_TAMOXIFEN_BREAST_2024,2prime_OMe_2prime_F_mixed,low_or_no_PS,0.05,low_PS,0,2prime_OMe_2prime_F_mixed|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_1,0.95,literature_grounded_generated_control,literature_context_control,literature_grounded_generated_control,dbbun_generated,literature_grounded_generated_control
MOD_OLIGO_CTRL_NEG_PMEVL_SEV_SIPCSK9_LOW_SYSTEMIC_TOX,OLIGO_CTRL_NEG_PMEVL_SEV_SIPCSK9_LOW_SYSTEMIC_TOX,WANG_PMEVL_SEV_SMALL_RNA_PCSK9_2026,not_applicable_sEV_payload_context,low_or_no_PS,0.0,low_PS,0,not_applicable_sEV_payload_context|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_0,0.95,literature_grounded_generated_control,RT_qPCR_NTA_TEM_Western_RNase_protection_IVIS_ALT_AST_H_E_proxy,literature_grounded_generated_control,dbbun_generated,literature_grounded_generated_control
MOD_OLIGO_CTRL_CONTEXT_PMEVL_N_MYRISTOYLATION_RNA_LOADING,OLIGO_CTRL_CONTEXT_PMEVL_N_MYRISTOYLATION_RNA_LOADING,WANG_PMEVL_SEV_SMALL_RNA_PCSK9_2026,not_applicable_sEV_payload_context,low_or_no_PS,0.0,low_PS,0,not_applicable_sEV_payload_context|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_0,0.95,literature_grounded_generated_control,RT_qPCR_NTA_TEM_Western_RNase_protection_IVIS_ALT_AST_H_E_proxy,literature_grounded_generated_control,dbbun_generated,literature_grounded_generated_control
MOD_OLIGO_CTRL_CONTEXT_PMEVL_ERK_AMPK_ANXA2_ESCRT_MECHANISM,OLIGO_CTRL_CONTEXT_PMEVL_ERK_AMPK_ANXA2_ESCRT_MECHANISM,WANG_PMEVL_SEV_SMALL_RNA_PCSK9_2026,not_applicable_sEV_payload_context,low_or_no_PS,0.0,low_PS,0,not_applicable_sEV_payload_context|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_0,0.95,literature_grounded_generated_control,RT_qPCR_NTA_TEM_Western_RNase_protection_IVIS_ALT_AST_H_E_proxy,literature_grounded_generated_control,dbbun_generated,literature_grounded_generated_control
MOD_OLIGO_CTRL_CONTEXT_PRECLINICAL_OLIGO_SAFETY_FRAMEWORK,OLIGO_CTRL_CONTEXT_PRECLINICAL_OLIGO_SAFETY_FRAMEWORK,ANDERSSON_PRECLINICAL_OLIGO_SAFETY_2022,MOE_or_mixed_OND_context,partial_PS,0.65,medium_PS,0,MOE_or_mixed_OND_context|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_12,0.96,literature_grounded_generated_control,preclinical_safety_screening_cascade_ALT_AST_kidney_complement_platelet_offtarget_proxy,literature_grounded_generated_control,dbbun_generated,literature_grounded_generated_control
MOD_OLIGO_CTRL_POS_SEQUENCE_MOTIF_GAPMER_LIVER_RISK,OLIGO_CTRL_POS_SEQUENCE_MOTIF_GAPMER_LIVER_RISK,ANDERSSON_PRECLINICAL_OLIGO_SAFETY_2022,LNA_cEt_high_affinity,high_PS,1.0,high_PS,0,LNA_cEt_high_affinity|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_17,0.96,literature_grounded_generated_control,preclinical_safety_screening_cascade_ALT_AST_kidney_complement_platelet_offtarget_proxy,literature_grounded_generated_control,dbbun_generated,literature_grounded_generated_control
MOD_OLIGO_CTRL_CONTEXT_HYBRIDIZATION_OFFTARGET_SCREENING,OLIGO_CTRL_CONTEXT_HYBRIDIZATION_OFFTARGET_SCREENING,ANDERSSON_PRECLINICAL_OLIGO_SAFETY_2022,MOE_or_mixed_OND_context,partial_PS,0.65,medium_PS,0,MOE_or_mixed_OND_context|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_12,0.96,literature_grounded_generated_control,preclinical_safety_screening_cascade_ALT_AST_kidney_complement_platelet_offtarget_proxy,literature_grounded_generated_control,dbbun_generated,literature_grounded_generated_control
MOD_OLIGO_CTRL_CONTEXT_GALNAC_PRODUCTIVE_UPTAKE_HEPATOCYTE,OLIGO_CTRL_CONTEXT_GALNAC_PRODUCTIVE_UPTAKE_HEPATOCYTE,ANDERSSON_PRECLINICAL_OLIGO_SAFETY_2022,2OMe_2F_stabilized,partial_PS,0.25,low_PS,1,2OMe_2F_stabilized|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_5,0.96,literature_grounded_generated_control,preclinical_safety_screening_cascade_ALT_AST_kidney_complement_platelet_offtarget_proxy,literature_grounded_generated_control,dbbun_generated,literature_grounded_generated_control
MOD_OLIGO_CTRL_CONTEXT_CMAX_COMPLEMENT_COAGULATION_MONITORING,OLIGO_CTRL_CONTEXT_CMAX_COMPLEMENT_COAGULATION_MONITORING,ANDERSSON_PRECLINICAL_OLIGO_SAFETY_2022,MOE_or_mixed_OND_context,partial_PS,0.65,medium_PS,0,MOE_or_mixed_OND_context|medium_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_12,0.96,literature_grounded_generated_control,preclinical_safety_screening_cascade_ALT_AST_kidney_complement_platelet_offtarget_proxy,literature_grounded_generated_control,dbbun_generated,literature_grounded_generated_control
MOD_OLIGO_CTRL_POS_IFNA_DISULFIDPTOSIS_HCC,OLIGO_CTRL_POS_IFNA_DISULFIDPTOSIS_HCC,BI_IFNA_DISULFIDPTOSIS_HCC_2026,unmodified_or_contextual,low_or_no_PS,0.0,low_PS,0,unmodified_or_contextual|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_0,0.97,literature_grounded_generated_control,IFN_alpha_disulfidptosis_context_nonreducing_WB_NADPH_Factin_siRNA_proxy,literature_grounded_generated_control,dbbun_generated,literature_grounded_generated_control
MOD_OLIGO_CTRL_NEG_DPEN_DISULFIDPTOSIS_RESCUE,OLIGO_CTRL_NEG_DPEN_DISULFIDPTOSIS_RESCUE,BI_IFNA_DISULFIDPTOSIS_HCC_2026,unmodified_or_contextual,low_or_no_PS,0.0,low_PS,0,unmodified_or_contextual|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_0,0.97,literature_grounded_generated_control,IFN_alpha_disulfidptosis_context_nonreducing_WB_NADPH_Factin_siRNA_proxy,literature_grounded_generated_control,dbbun_generated,literature_grounded_generated_control
MOD_OLIGO_CTRL_CONTEXT_SLC7A11_KD_IFNA_AGGRAVATION,OLIGO_CTRL_CONTEXT_SLC7A11_KD_IFNA_AGGRAVATION,BI_IFNA_DISULFIDPTOSIS_HCC_2026,unmodified_or_contextual,low_or_no_PS,0.0,low_PS,0,unmodified_or_contextual|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_0,0.97,literature_grounded_generated_control,IFN_alpha_disulfidptosis_context_nonreducing_WB_NADPH_Factin_siRNA_proxy,literature_grounded_generated_control,dbbun_generated,literature_grounded_generated_control
MOD_OLIGO_CTRL_CONTEXT_IFNA_ISG_B2M_USP18_PSME1,OLIGO_CTRL_CONTEXT_IFNA_ISG_B2M_USP18_PSME1,BI_IFNA_DISULFIDPTOSIS_HCC_2026,unmodified_or_contextual,low_or_no_PS,0.0,low_PS,0,unmodified_or_contextual|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_0,0.97,literature_grounded_generated_control,IFN_alpha_disulfidptosis_context_nonreducing_WB_NADPH_Factin_siRNA_proxy,literature_grounded_generated_control,dbbun_generated,literature_grounded_generated_control
MOD_OLIGO_CTRL_NEG_GALNAC_ESC_SIRNA_PLATFORM_LOW_TOX,OLIGO_CTRL_NEG_GALNAC_ESC_SIRNA_PLATFORM_LOW_TOX,JANAS_GALNAC_RNAI_NONCLINICAL_SAFETY_2018,mixed_2prime_OMe_2prime_F_ESC,partial_PS,0.2,low_PS,1,mixed_2prime_OMe_2prime_F_ESC|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_4,0.98,literature_grounded_generated_control,rat_monkey_repeat_dose_toxicology_platform_safety_generated_proxy,literature_grounded_generated_control,dbbun_generated,literature_grounded_generated_control
MOD_OLIGO_CTRL_POS_GALNAC_SIRNA_SEED_OFFTARGET_RAT_HEPATOTOX,OLIGO_CTRL_POS_GALNAC_SIRNA_SEED_OFFTARGET_RAT_HEPATOTOX,JANAS_GALNAC_RNAI_NONCLINICAL_SAFETY_2018,mixed_2prime_OMe_2prime_F_ESC,partial_PS,0.2,low_PS,1,mixed_2prime_OMe_2prime_F_ESC|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_4,0.98,literature_grounded_generated_control,rat_monkey_repeat_dose_toxicology_platform_safety_generated_proxy,literature_grounded_generated_control,dbbun_generated,literature_grounded_generated_control
MOD_OLIGO_CTRL_CONTEXT_GALNAC_SIRNA_LIVER_KIDNEY_RES_DISTRIBUTION,OLIGO_CTRL_CONTEXT_GALNAC_SIRNA_LIVER_KIDNEY_RES_DISTRIBUTION,JANAS_GALNAC_RNAI_NONCLINICAL_SAFETY_2018,mixed_2prime_OMe_2prime_F_ESC,partial_PS,0.2,low_PS,1,mixed_2prime_OMe_2prime_F_ESC|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_4,0.98,literature_grounded_generated_control,rat_monkey_repeat_dose_toxicology_platform_safety_generated_proxy,literature_grounded_generated_control,dbbun_generated,literature_grounded_generated_control
MOD_OLIGO_CTRL_CONTEXT_INCLISIRAN_FH_LDL_PWV_RESPONSE,OLIGO_CTRL_CONTEXT_INCLISIRAN_FH_LDL_PWV_RESPONSE,BOSCO_INCLISIRAN_FH_REALWORLD_2025,mixed_2prime_OMe_2prime_F_ESC,partial_PS,0.2,low_PS,1,mixed_2prime_OMe_2prime_F_ESC|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_4,0.98,literature_grounded_generated_control,real_world_six_month_lipid_PWV_ALT_AST_CPK_monitoring_generated_proxy,literature_grounded_generated_control,dbbun_generated,literature_grounded_generated_control
MOD_OLIGO_CTRL_NEG_INCLISIRAN_ALT_AST_STABLE_REALWORLD,OLIGO_CTRL_NEG_INCLISIRAN_ALT_AST_STABLE_REALWORLD,BOSCO_INCLISIRAN_FH_REALWORLD_2025,mixed_2prime_OMe_2prime_F_ESC,partial_PS,0.2,low_PS,1,mixed_2prime_OMe_2prime_F_ESC|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_4,0.98,literature_grounded_generated_control,real_world_six_month_lipid_PWV_ALT_AST_CPK_monitoring_generated_proxy,literature_grounded_generated_control,dbbun_generated,literature_grounded_generated_control
MOD_OLIGO_CTRL_CONTEXT_GALNAC_ASGPR_LIVER_DELIVERY_REVIEW,OLIGO_CTRL_CONTEXT_GALNAC_ASGPR_LIVER_DELIVERY_REVIEW,DEBACKER_GALNAC_LIVER_DELIVERY_REVIEW_2020,mixed_2prime_OMe_2prime_F_ESC_or_MOE_gapmer_context,high_PS,0.85,high_PS,1,mixed_2prime_OMe_2prime_F_ESC_or_MOE_gapmer_context|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_17,0.98,literature_grounded_generated_control,GalNAc_ASGPR_liver_delivery_review_generated_proxy,literature_grounded_generated_control,dbbun_generated,literature_grounded_generated_control
MOD_OLIGO_CTRL_CONTEXT_GALNAC_ASO_HEPATOCYTE_UPTAKE_POTENCY,OLIGO_CTRL_CONTEXT_GALNAC_ASO_HEPATOCYTE_UPTAKE_POTENCY,DEBACKER_GALNAC_LIVER_DELIVERY_REVIEW_2020,mixed_2prime_OMe_2prime_F_ESC_or_MOE_gapmer_context,high_PS,0.85,high_PS,1,mixed_2prime_OMe_2prime_F_ESC_or_MOE_gapmer_context|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_14,0.98,literature_grounded_generated_control,GalNAc_ASGPR_liver_delivery_review_generated_proxy,literature_grounded_generated_control,dbbun_generated,literature_grounded_generated_control
MOD_OLIGO_CTRL_CONTEXT_GALNAC_SIRNA_ESCPLUS_SEED_SAFETY,OLIGO_CTRL_CONTEXT_GALNAC_SIRNA_ESCPLUS_SEED_SAFETY,DEBACKER_GALNAC_LIVER_DELIVERY_REVIEW_2020,mixed_2prime_OMe_2prime_F_ESC_or_MOE_gapmer_context,partial_PS,0.2,low_PS,1,mixed_2prime_OMe_2prime_F_ESC_or_MOE_gapmer_context|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_4,0.98,literature_grounded_generated_control,GalNAc_ASGPR_liver_delivery_review_generated_proxy,literature_grounded_generated_control,dbbun_generated,literature_grounded_generated_control
MOD_OLIGO_CTRL_CONTEXT_GALNAC_REVERSIR_REVERSAL_SAFETY,OLIGO_CTRL_CONTEXT_GALNAC_REVERSIR_REVERSAL_SAFETY,DEBACKER_GALNAC_LIVER_DELIVERY_REVIEW_2020,mixed_2prime_OMe_2prime_F_ESC_or_MOE_gapmer_context,high_PS,0.85,high_PS,1,mixed_2prime_OMe_2prime_F_ESC_or_MOE_gapmer_context|high_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_17,0.98,literature_grounded_generated_control,GalNAc_ASGPR_liver_delivery_review_generated_proxy,literature_grounded_generated_control,dbbun_generated,literature_grounded_generated_control
MOD_OLIGO_CTRL_CONTEXT_SIRNA_RISC_AGO2_MECHANISM,OLIGO_CTRL_CONTEXT_SIRNA_RISC_AGO2_MECHANISM,RANASINGHE_SIRNA_PHARMACOLOGY_REVIEW_2023,2prime_OMe_2prime_F_or_unmodified_context,partial_PS,0.12,low_PS,1,2prime_OMe_2prime_F_or_unmodified_context|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_2,0.98,literature_grounded_generated_control,RISC_GalNAc_PKPD_safety_clinical_review_generated_proxy,literature_grounded_generated_control,dbbun_generated,literature_grounded_generated_control
MOD_OLIGO_CTRL_CONTEXT_SIRNA_PKPD_BARRIERS,OLIGO_CTRL_CONTEXT_SIRNA_PKPD_BARRIERS,RANASINGHE_SIRNA_PHARMACOLOGY_REVIEW_2023,2prime_OMe_2prime_F_or_unmodified_context,low_or_no_PS,0.0,low_PS,0,2prime_OMe_2prime_F_or_unmodified_context|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_0,0.98,literature_grounded_generated_control,RISC_GalNAc_PKPD_safety_clinical_review_generated_proxy,literature_grounded_generated_control,dbbun_generated,literature_grounded_generated_control
MOD_OLIGO_CTRL_CONTEXT_SIRNA_IMMUNE_OFFTARGET_SCREENING,OLIGO_CTRL_CONTEXT_SIRNA_IMMUNE_OFFTARGET_SCREENING,RANASINGHE_SIRNA_PHARMACOLOGY_REVIEW_2023,2prime_OMe_2prime_F_or_unmodified_context,partial_PS,0.12,low_PS,0,2prime_OMe_2prime_F_or_unmodified_context|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_2,0.98,literature_grounded_generated_control,RISC_GalNAc_PKPD_safety_clinical_review_generated_proxy,literature_grounded_generated_control,dbbun_generated,literature_grounded_generated_control
MOD_OLIGO_CTRL_CONTEXT_APPROVED_GALNAC_SIRNA_CLINICAL_TRANSLATION,OLIGO_CTRL_CONTEXT_APPROVED_GALNAC_SIRNA_CLINICAL_TRANSLATION,RANASINGHE_SIRNA_PHARMACOLOGY_REVIEW_2023,2prime_OMe_2prime_F_or_unmodified_context,partial_PS,0.12,low_PS,1,2prime_OMe_2prime_F_or_unmodified_context|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_2,0.98,literature_grounded_generated_control,RISC_GalNAc_PKPD_safety_clinical_review_generated_proxy,literature_grounded_generated_control,dbbun_generated,literature_grounded_generated_control
MOD_OLIGO_CTRL_POS_LNA_GAPMER_HIGH_OTE_ALT_AST,OLIGO_CTRL_POS_LNA_GAPMER_HIGH_OTE_ALT_AST,KAMOLA_ASO_HEPATOTOX_SCREEN_2017,LNA_gapmer_wings_context,high_PS,1.0,high_PS,0,LNA_gapmer_wings_context|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_13,0.98,literature_grounded_generated_control,ALT_AST_liver_weight_RNAseq_OTE_selectivity_screen_generated_proxy,literature_grounded_generated_control,dbbun_generated,literature_grounded_generated_control
MOD_OLIGO_CTRL_NEG_LNA_GAPMER_SELECTIVE_LOW_HEPATOX,OLIGO_CTRL_NEG_LNA_GAPMER_SELECTIVE_LOW_HEPATOX,KAMOLA_ASO_HEPATOTOX_SCREEN_2017,LNA_gapmer_wings_context,high_PS,1.0,high_PS,0,LNA_gapmer_wings_context|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_15,0.98,literature_grounded_generated_control,ALT_AST_liver_weight_RNAseq_OTE_selectivity_screen_generated_proxy,literature_grounded_generated_control,dbbun_generated,literature_grounded_generated_control
MOD_OLIGO_CTRL_CONTEXT_ACUTE_MOUSE_ASO_HEPATOX_SCREEN,OLIGO_CTRL_CONTEXT_ACUTE_MOUSE_ASO_HEPATOX_SCREEN,KAMOLA_ASO_HEPATOTOX_SCREEN_2017,LNA_gapmer_wings_context,high_PS,1.0,high_PS,0,LNA_gapmer_wings_context|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_15,0.98,literature_grounded_generated_control,ALT_AST_liver_weight_RNAseq_OTE_selectivity_screen_generated_proxy,literature_grounded_generated_control,dbbun_generated,literature_grounded_generated_control
MOD_OLIGO_CTRL_CONTEXT_TRANSCRIPTOME_WIDE_OTE_SELECTIVITY,OLIGO_CTRL_CONTEXT_TRANSCRIPTOME_WIDE_OTE_SELECTIVITY,KAMOLA_ASO_HEPATOTOX_SCREEN_2017,LNA_gapmer_wings_context,high_PS,1.0,high_PS,0,LNA_gapmer_wings_context|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_13,0.98,literature_grounded_generated_control,ALT_AST_liver_weight_RNAseq_OTE_selectivity_screen_generated_proxy,literature_grounded_generated_control,dbbun_generated,literature_grounded_generated_control
MOD_OLIGO_CTRL_NEG_LNP_AGO1_ASO_ALT_AST_STABLE,OLIGO_CTRL_NEG_LNP_AGO1_ASO_ALT_AST_STABLE,LIU_ENDOTHELIAL_AGO1_LNP_ASO_2025,LNA_gapmer_wings_context,high_PS,1.0,high_PS,0,LNA_gapmer_wings_context|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_15,0.98,literature_grounded_generated_control,ALT_AST_lipid_profile_liver_histology_inflammatory_gene_expression_generated_proxy,literature_grounded_generated_control,dbbun_generated,literature_grounded_generated_control
MOD_OLIGO_CTRL_CONTEXT_ENDOTHELIAL_AGO1_NFKB_INFLAMMATION,OLIGO_CTRL_CONTEXT_ENDOTHELIAL_AGO1_NFKB_INFLAMMATION,LIU_ENDOTHELIAL_AGO1_LNP_ASO_2025,LNA_gapmer_wings_context,high_PS,1.0,high_PS,0,LNA_gapmer_wings_context|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_15,0.98,literature_grounded_generated_control,ALT_AST_lipid_profile_liver_histology_inflammatory_gene_expression_generated_proxy,literature_grounded_generated_control,dbbun_generated,literature_grounded_generated_control
MOD_OLIGO_CTRL_CONTEXT_LNP_ASO_HYPERLIPIDEMIA_LIVER_FUNCTION,OLIGO_CTRL_CONTEXT_LNP_ASO_HYPERLIPIDEMIA_LIVER_FUNCTION,LIU_ENDOTHELIAL_AGO1_LNP_ASO_2025,LNA_gapmer_wings_context,high_PS,1.0,high_PS,0,LNA_gapmer_wings_context|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_15,0.98,literature_grounded_generated_control,ALT_AST_lipid_profile_liver_histology_inflammatory_gene_expression_generated_proxy,literature_grounded_generated_control,dbbun_generated,literature_grounded_generated_control
MOD_OLIGO_CTRL_CONTEXT_EC_HEPATOCYTE_PARACRINE_METABOLISM,OLIGO_CTRL_CONTEXT_EC_HEPATOCYTE_PARACRINE_METABOLISM,LIU_ENDOTHELIAL_AGO1_LNP_ASO_2025,LNA_gapmer_wings_context,high_PS,1.0,high_PS,0,LNA_gapmer_wings_context|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_15,0.98,literature_grounded_generated_control,ALT_AST_lipid_profile_liver_histology_inflammatory_gene_expression_generated_proxy,literature_grounded_generated_control,dbbun_generated,literature_grounded_generated_control
MOD_OLIGO_CTRL_NEG_GYS1_ASO_NO_ALT_AST_ELEVATION,OLIGO_CTRL_NEG_GYS1_ASO_NO_ALT_AST_ELEVATION,WEISS_GYS1_ASO_POMPE_PREPRINT_2024,2prime_constrained_ethyl_cEt,high_PS,1.0,high_PS,0,2prime_constrained_ethyl_cEt|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_15,0.98,literature_grounded_generated_control,systemic_ASO_tolerability_monitoring_generated_proxy,literature_grounded_generated_control,dbbun_generated,literature_grounded_generated_control
MOD_OLIGO_CTRL_CONTEXT_GYS1_ASO_SUBSTRATE_REDUCTION_POMPE,OLIGO_CTRL_CONTEXT_GYS1_ASO_SUBSTRATE_REDUCTION_POMPE,WEISS_GYS1_ASO_POMPE_PREPRINT_2024,2prime_constrained_ethyl_cEt,high_PS,1.0,high_PS,0,2prime_constrained_ethyl_cEt|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_15,0.98,literature_grounded_generated_control,systemic_ASO_tolerability_monitoring_generated_proxy,literature_grounded_generated_control,dbbun_generated,literature_grounded_generated_control
MOD_OLIGO_CTRL_CONTEXT_GYS1_ASO_ERT_COMBINATION,OLIGO_CTRL_CONTEXT_GYS1_ASO_ERT_COMBINATION,WEISS_GYS1_ASO_POMPE_PREPRINT_2024,2prime_constrained_ethyl_cEt,high_PS,1.0,high_PS,0,2prime_constrained_ethyl_cEt|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_15,0.98,literature_grounded_generated_control,systemic_ASO_tolerability_monitoring_generated_proxy,literature_grounded_generated_control,dbbun_generated,literature_grounded_generated_control
MOD_OLIGO_CTRL_CONTEXT_GYS1_GYS2_ISOFORM_SPECIFICITY,OLIGO_CTRL_CONTEXT_GYS1_GYS2_ISOFORM_SPECIFICITY,WEISS_GYS1_ASO_POMPE_PREPRINT_2024,2prime_constrained_ethyl_cEt,high_PS,1.0,high_PS,0,2prime_constrained_ethyl_cEt|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_15,0.98,literature_grounded_generated_control,systemic_ASO_tolerability_monitoring_generated_proxy,literature_grounded_generated_control,dbbun_generated,literature_grounded_generated_control
MOD_OLIGO_CTRL_POS_DDC_CHOLESTATIC_LIVER_INJURY_ALT_ALP_BILI,OLIGO_CTRL_POS_DDC_CHOLESTATIC_LIVER_INJURY_ALT_ALP_BILI,OLSON_CHOLANGIOCYTE_CHOLESTASIS_2025,not_applicable,low_or_no_PS,0.0,low_PS,0,not_applicable|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_0,0.98,literature_grounded_generated_control,cholestasis_cholangiocyte_context_generated_proxy,literature_grounded_generated_control,dbbun_generated,literature_grounded_generated_control
MOD_OLIGO_CTRL_NEG_CHOLESTASIS_RECOVERY_R15_RESOLUTION,OLIGO_CTRL_NEG_CHOLESTASIS_RECOVERY_R15_RESOLUTION,OLSON_CHOLANGIOCYTE_CHOLESTASIS_2025,not_applicable,low_or_no_PS,0.0,low_PS,0,not_applicable|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_0,0.98,literature_grounded_generated_control,cholestasis_cholangiocyte_context_generated_proxy,literature_grounded_generated_control,dbbun_generated,literature_grounded_generated_control
MOD_OLIGO_CTRL_CONTEXT_CX3CL1_CX3CR1_MACROPHAGE_RECRUITMENT,OLIGO_CTRL_CONTEXT_CX3CL1_CX3CR1_MACROPHAGE_RECRUITMENT,OLSON_CHOLANGIOCYTE_CHOLESTASIS_2025,not_applicable,low_or_no_PS,0.0,low_PS,0,not_applicable|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_0,0.98,literature_grounded_generated_control,cholestasis_cholangiocyte_context_generated_proxy,literature_grounded_generated_control,dbbun_generated,literature_grounded_generated_control
MOD_OLIGO_CTRL_CONTEXT_NFYA_TGFB1_CHOLANGIOCYTE_FIBROSIS,OLIGO_CTRL_CONTEXT_NFYA_TGFB1_CHOLANGIOCYTE_FIBROSIS,OLSON_CHOLANGIOCYTE_CHOLESTASIS_2025,unmodified_siRNA_context,low_or_no_PS,0.0,low_PS,0,unmodified_siRNA_context|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_0,0.98,literature_grounded_generated_control,cholestasis_cholangiocyte_context_generated_proxy,literature_grounded_generated_control,dbbun_generated,literature_grounded_generated_control
MOD_OLIGO_CTRL_NEG_PCDHA11_AMNA_2255_LOW_REVERSIBLE_LIVER_SIGNAL,OLIGO_CTRL_NEG_PCDHA11_AMNA_2255_LOW_REVERSIBLE_LIVER_SIGNAL,KANDA_PCDHA11_AMNA_ASO_2024,AmNA,high_PS,1.0,high_PS,0,AmNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_17,0.98113,inferred_from_paper,AmNA_ASO_synthesis_HPLC_LCMS_qPCR_microarray_toxicology_generated_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_CTRL_NEG_PCDHA11_AMNA_3319_LOW_OFFTARGET_LIVER_SIGNAL,OLIGO_CTRL_NEG_PCDHA11_AMNA_3319_LOW_OFFTARGET_LIVER_SIGNAL,KANDA_PCDHA11_AMNA_ASO_2024,AmNA,high_PS,1.0,high_PS,0,AmNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_17,0.9739,inferred_from_paper,AmNA_ASO_synthesis_HPLC_LCMS_qPCR_microarray_toxicology_generated_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_CTRL_POS_PCDHA11_AMNA_3969_SEQUENCE_DEPENDENT_LIVER_INJURY,OLIGO_CTRL_POS_PCDHA11_AMNA_3969_SEQUENCE_DEPENDENT_LIVER_INJURY,KANDA_PCDHA11_AMNA_ASO_2024,AmNA,high_PS,1.0,high_PS,0,AmNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_17,0.98463,inferred_from_paper,AmNA_ASO_synthesis_HPLC_LCMS_qPCR_microarray_toxicology_generated_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_CTRL_CONTEXT_PCDHA11_AMNA_OFFTARGET_MICROARRAY_SCREEN,OLIGO_CTRL_CONTEXT_PCDHA11_AMNA_OFFTARGET_MICROARRAY_SCREEN,KANDA_PCDHA11_AMNA_ASO_2024,AmNA,high_PS,1.0,high_PS,0,AmNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_17,0.98033,inferred_from_paper,AmNA_ASO_synthesis_HPLC_LCMS_qPCR_microarray_toxicology_generated_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_CTRL_CONTEXT_PCDHA11_KO_TARGET_SPECIFICITY_APOPTOSIS,OLIGO_CTRL_CONTEXT_PCDHA11_KO_TARGET_SPECIFICITY_APOPTOSIS,KANDA_PCDHA11_AMNA_ASO_2024,AmNA,high_PS,1.0,high_PS,0,AmNA|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_17,0.96625,inferred_from_paper,AmNA_ASO_synthesis_HPLC_LCMS_qPCR_microarray_toxicology_generated_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_CTRL_POS_PS_ASO_DDR_HIGH_CONDENSATE,OLIGO_CTRL_POS_PS_ASO_DDR_HIGH_CONDENSATE,HJELMGREN_PS_ASO_DDR_2026,DNA_PS,high_PS,0.95,high_PS,0,DNA_PS|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_17,0.97,inferred_from_paper,fluorescent_ASO_imaging_Western_blot_pull_down_generated_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_CTRL_NEG_PO_ASO_LOW_DDR_NO_PS_BODY,OLIGO_CTRL_NEG_PO_ASO_LOW_DDR_NO_PS_BODY,HJELMGREN_PS_ASO_DDR_2026,DNA_or_RNA_PO_backbone_contrast,low_or_no_PS,0.0,low_PS,0,DNA_or_RNA_PO_backbone_contrast|low_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_0,0.97,inferred_from_paper,fluorescent_ASO_imaging_Western_blot_pull_down_generated_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_CTRL_CONTEXT_ASO_REPAIR_PROTEIN_BINDING,OLIGO_CTRL_CONTEXT_ASO_REPAIR_PROTEIN_BINDING,HJELMGREN_PS_ASO_DDR_2026,mixed_LNA_DNA_gapmer,high_PS,0.9,high_PS,0,mixed_LNA_DNA_gapmer|high_PS|GalNAc=0,generated_terminal_and_internal_pattern_PS_count_16,0.97,inferred_from_paper,fluorescent_ASO_imaging_Western_blot_pull_down_generated_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_CTRL_NEG_SIRUBICON_ROS_GALNAC_LIVER_FUNCTION_IMPROVED,OLIGO_CTRL_NEG_SIRUBICON_ROS_GALNAC_LIVER_FUNCTION_IMPROVED,LAN_SIRUBICON_ROS_GALNAC_MASH_2025,mixed_2prime_F_2prime_OMe_siRNA,partial_PS,0.28,low_PS,1,mixed_2prime_F_2prime_OMe_siRNA|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_6,0.97,inferred_from_paper,nanoparticle_DLS_zeta_biodistribution_Rubicon_knockdown_ALT_AST_generated_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_CTRL_CONTEXT_ROS_GALNAC_HEPATOCYTE_TARGETING,OLIGO_CTRL_CONTEXT_ROS_GALNAC_HEPATOCYTE_TARGETING,LAN_SIRUBICON_ROS_GALNAC_MASH_2025,mixed_2prime_F_2prime_OMe_siRNA,partial_PS,0.28,low_PS,1,mixed_2prime_F_2prime_OMe_siRNA|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_6,0.97,inferred_from_paper,nanoparticle_DLS_zeta_biodistribution_Rubicon_knockdown_ALT_AST_generated_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper
MOD_OLIGO_CTRL_CONTEXT_PEI_NANOCARRIER_SAFETY_MONITORING,OLIGO_CTRL_CONTEXT_PEI_NANOCARRIER_SAFETY_MONITORING,LAN_SIRUBICON_ROS_GALNAC_MASH_2025,mixed_2prime_F_2prime_OMe_siRNA,partial_PS,0.28,low_PS,1,mixed_2prime_F_2prime_OMe_siRNA|low_PS|GalNAc=1,generated_terminal_and_internal_pattern_PS_count_6,0.97,inferred_from_paper,nanoparticle_DLS_zeta_biodistribution_Rubicon_knockdown_ALT_AST_generated_proxy,inferred_from_paper,dbbun_generated,inferred_from_paper