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values | doi stringlengths 28 82 ⌀ | description stringclasses 266
values | title stringlengths 14 500 | concepts listlengths 2 22 | abstract stringlengths 10k 43.8k |
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C126322002 | Internal medicine | https://doi.org/10.1159/000453569 | medical specialty dealing with the prevention, diagnosis, and treatment of adult diseases | PD-1 and PD-L1 Immune Checkpoint Blockade to Treat Breast Cancer | [
{
"display_name": "Blockade",
"id": "https://openalex.org/C2778468042",
"level": 3,
"score": 0.7910926,
"wikidata": "https://www.wikidata.org/wiki/Q273976"
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{
"display_name": "Medicine",
"id": "https://openalex.org/C71924100",
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"wikidata":... | Immune checkpoint inhibition represents a major recent breakthrough in the treatment of malignant diseases including breast cancer. Blocking the programmed death receptor-1 (PD-1) and its ligand, PD-L1, has shown impressive antitumor activity and may lead to durable long-term disease control, especially in the triple-n... |
C126322002 | Internal medicine | https://doi.org/10.1159/000468530 | medical specialty dealing with the prevention, diagnosis, and treatment of adult diseases | Magnesium Replacement Improves the Metabolic Profile in Obese and Pre-Diabetic Patients with Mild-to-Moderate Chronic Kidney Disease: A 3-Month, Randomised, Double-Blind, Placebo-Controlled Study | [
{
"display_name": "Medicine",
"id": "https://openalex.org/C71924100",
"level": 0,
"score": 0.8433229,
"wikidata": "https://www.wikidata.org/wiki/Q11190"
},
{
"display_name": "Internal medicine",
"id": "https://openalex.org/C126322002",
"level": 1,
"score": 0.73243636,
"wi... | Epidemiological studies have associated low dietary Mg2+ intake with insulin resistance (IR) and increased risk for metabolic syndrome; however, the effect of Mg2+ supplementation on IR has not been adequately investigated. This study aimed to investigate the effects of oral Mg2+ supplementation on insulin sensitivity ... |
C126322002 | Internal medicine | https://doi.org/10.1056/nejm199309303291401 | medical specialty dealing with the prevention, diagnosis, and treatment of adult diseases | The Effect of Intensive Treatment of Diabetes on the Development and Progression of Long-Term Complications in Insulin-Dependent Diabetes Mellitus | [
{
"display_name": "Medicine",
"id": "https://openalex.org/C71924100",
"level": 0,
"score": 0.9629593,
"wikidata": "https://www.wikidata.org/wiki/Q11190"
},
{
"display_name": "Diabetes mellitus",
"id": "https://openalex.org/C555293320",
"level": 2,
"score": 0.89244187,
"wi... | Long-term microvascular and neurologic complications cause major morbidity and mortality in patients with insulin-dependent diabetes mellitus (IDDM). We examined whether intensive treatment with the goal of maintaining blood glucose concentrations close to the normal range could decrease the frequency and severity of t... |
C126322002 | Internal medicine | https://doi.org/10.1159/000454668 | medical specialty dealing with the prevention, diagnosis, and treatment of adult diseases | The “Golden Age” of Probiotics: A Systematic Review and Meta-Analysis of Randomized and Observational Studies in Preterm Infants | [
{
"display_name": "Medicine",
"id": "https://openalex.org/C71924100",
"level": 0,
"score": 0.89709544,
"wikidata": "https://www.wikidata.org/wiki/Q11190"
},
{
"display_name": "Mucositis",
"id": "https://openalex.org/C2778496288",
"level": 3,
"score": 0.7992532,
"wikidata"... | This review reports the beneficial effects, observed in our clinical studies, of Bifidobacterium breve for premature infants, and children with cancers undergoing chemotherapy. To investigate the protective effects of B. breve (M-16V) as a probiotic on necrotizing enterocolitis (NEC) and infection in premature infants,... |
C126322002 | Internal medicine | https://doi.org/10.1056/nejmoa043330 | medical specialty dealing with the prevention, diagnosis, and treatment of adult diseases | Radiotherapy plus Concomitant and Adjuvant Temozolomide for Glioblastoma | [
{
"display_name": "Temozolomide",
"id": "https://openalex.org/C2777389519",
"level": 3,
"score": 0.97642064,
"wikidata": "https://www.wikidata.org/wiki/Q425088"
},
{
"display_name": "Medicine",
"id": "https://openalex.org/C71924100",
"level": 0,
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"wiki... | Glioblastoma, the most common primary brain tumor in adults, is usually rapidly fatal. The current standard of care for newly diagnosed glioblastoma is surgical resection to the extent feasible, followed by adjuvant radiotherapy. In this trial we compared radiotherapy alone with radiotherapy plus temozolomide, given co... |
C126322002 | Internal medicine | https://doi.org/10.1056/nejmoa012512 | medical specialty dealing with the prevention, diagnosis, and treatment of adult diseases | Reduction in the Incidence of Type 2 Diabetes with Lifestyle Intervention or Metformin | [
{
"display_name": "Metformin",
"id": "https://openalex.org/C2780323712",
"level": 3,
"score": 0.8987744,
"wikidata": "https://www.wikidata.org/wiki/Q19484"
},
{
"display_name": "Medicine",
"id": "https://openalex.org/C71924100",
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"wikidata":... | Type 2 diabetes affects approximately 8 percent of adults in the United States. Some risk factors — elevated plasma glucose concentrations in the fasting state and after an oral glucose load, overweight, and a sedentary lifestyle — are potentially reversible. We hypothesized that modifying these factors with a lifestyl... |
C126322002 | Internal medicine | https://doi.org/10.1001/jama.2020.1585 | medical specialty dealing with the prevention, diagnosis, and treatment of adult diseases | Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus–Infected Pneumonia in Wuhan, China | [
{
"display_name": "Medicine",
"id": "https://openalex.org/C71924100",
"level": 0,
"score": 0.96207094,
"wikidata": "https://www.wikidata.org/wiki/Q11190"
},
{
"display_name": "Interquartile range",
"id": "https://openalex.org/C119060515",
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"... | <h3>Importance</h3> In December 2019, novel coronavirus (2019-nCoV)–infected pneumonia (NCIP) occurred in Wuhan, China. The number of cases has increased rapidly but information on the clinical characteristics of affected patients is limited. <h3>Objective</h3> To describe the epidemiological and clinical characteristi... |
C126322002 | Internal medicine | https://doi.org/10.1001/jama.288.3.321 | medical specialty dealing with the prevention, diagnosis, and treatment of adult diseases | Risks and Benefits of Estrogen Plus Progestin in Healthy Postmenopausal Women: Principal Results From the Women's Health Initiative Randomized Controlled Trial | [
{
"display_name": "Medicine",
"id": "https://openalex.org/C71924100",
"level": 0,
"score": 0.95408595,
"wikidata": "https://www.wikidata.org/wiki/Q11190"
},
{
"display_name": "Women's Health Initiative",
"id": "https://openalex.org/C2780733421",
"level": 3,
"score": 0.8339025... | ContextDespite decades of accumulated observational evidence, the balance of risks and benefits for hormone use in healthy postmenopausal women remains uncertain.ObjectiveTo assess the major health benefits and risks of the most commonly used combined hormone preparation in the United States.DesignEstrogen plus progest... |
C199539241 | Law | https://doi.org/10.1137/070710111 | system of rules and guidelines, generally backed by governmental authority | Power-Law Distributions in Empirical Data | [
{
"display_name": "Power law",
"id": "https://openalex.org/C87040749",
"level": 2,
"score": 0.67707694,
"wikidata": "https://www.wikidata.org/wiki/Q428971"
},
{
"display_name": "Goodness of fit",
"id": "https://openalex.org/C132480984",
"level": 2,
"score": 0.6538503,
"wi... | Power-law distributions occur in many situations of scientific interest and have significant consequences for our understanding of natural and man-made phenomena. Unfortunately, the detection and characterization of power laws is complicated by the large fluctuations that occur in the tail of the distribution—the part ... |
C199539241 | Law | https://doi.org/10.1080/00107510500052444 | system of rules and guidelines, generally backed by governmental authority | Power laws, Pareto distributions and Zipf's law | [
{
"display_name": "Zipf's law",
"id": "https://openalex.org/C125932096",
"level": 2,
"score": 0.8236861,
"wikidata": "https://www.wikidata.org/wiki/Q205472"
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{
"display_name": "Power law",
"id": "https://openalex.org/C87040749",
"level": 2,
"score": 0.6388278,
"wikidata... | Abstract When the probability of measuring a particular value of some quantity varies inversely as a power of that value, the quantity is said to follow a power law, also known variously as Zipf's law or the Pareto distribution. Power laws appear widely in physics, biology, earth and planetary sciences, economics and f... |
C199539241 | Law | https://doi.org/10.5860/choice.44-2056 | system of rules and guidelines, generally backed by governmental authority | Frontiers of justice: disability, nationality, species membership | [
{
"display_name": "Economic Justice",
"id": "https://openalex.org/C139621336",
"level": 2,
"score": 0.6649088,
"wikidata": "https://www.wikidata.org/wiki/Q3190382"
},
{
"display_name": "Politics",
"id": "https://openalex.org/C94625758",
"level": 2,
"score": 0.5969869,
"wi... | rather "as a nexus of distinctive sensibilities, cares, and concerns that are expressed in distinctive patterns of emotional and practical response" (p.236).Drawing on Philippa Foot and Simone Weil, Wiggins draws out the moral significance of solidarity and recognition."In recognizing another person, we recognize not m... |
C199539241 | Law | https://doi.org/10.1007/978-3-0348-8629-1 | system of rules and guidelines, generally backed by governmental authority | Numerical Methods for Conservation Laws | [
{
"display_name": "Conservation law",
"id": "https://openalex.org/C3445786",
"level": 2,
"score": 0.85613084,
"wikidata": "https://www.wikidata.org/wiki/Q205805"
},
{
"display_name": "Law",
"id": "https://openalex.org/C199539241",
"level": 1,
"score": 0.49978137,
"wikidat... | These notes developed from a course on the numerical solution of conservation laws first taught at the University of Washington in the fall of 1988 and then at ETH during the following spring. The ove ... |
C199539241 | Law | https://doi.org/10.5124/jkma.2014.57.11.899 | system of rules and guidelines, generally backed by governmental authority | World Medical Association Declaration of Helsinki: Ethical principles for medical research involving human subjects | [
{
"display_name": "Declaration of Helsinki",
"id": "https://openalex.org/C2775998707",
"level": 4,
"score": 0.841186,
"wikidata": "https://www.wikidata.org/wiki/Q777473"
},
{
"display_name": "Declaration",
"id": "https://openalex.org/C138147947",
"level": 2,
"score": 0.705608... | Published research in English-language journals are increasingly required to carry a statement that the study has been approved and monitored by an Institutional Review Board in conformance with 45 CFR 46 standards if the study was conducted in the United States. Alternative language attesting conformity with the Helsi... |
C199539241 | Law | https://doi.org/10.5194/acp-15-4399-2015 | system of rules and guidelines, generally backed by governmental authority | Compilation of Henry's law constants (version 4.0) for water as solvent | [
{
"display_name": "Henry's law",
"id": "https://openalex.org/C196616695",
"level": 3,
"score": 0.9546548,
"wikidata": "https://www.wikidata.org/wiki/Q285804"
},
{
"display_name": "Aerosol",
"id": "https://openalex.org/C2779345167",
"level": 2,
"score": 0.560571,
"wikidata... | Abstract. Many atmospheric chemicals occur in the gas phase as well as in liquid cloud droplets and aerosol particles. Therefore, it is necessary to understand the distribution between the phases. According to Henry's law, the equilibrium ratio between the abundances in the gas phase and in the aqueous phase is constan... |
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