Datasets:

ClarusC64
/

clinical-structural-similarity-scoring-against-ground-truth-v0.1

id stringclasses 10 values	case_id stringclasses 10 values	pre_explanation_summary stringclasses 10 values	pre_explanation_data stringclasses 10 values	predicted_structure stringclasses 10 values	ground_truth_structure stringclasses 10 values	structural_similarity_score_0_100 int64 74 92	alignment_strengths stringclasses 10 values	divergence_points stringclasses 10 values	constraints stringclasses 1 value	gold_checklist stringclasses 1 value
SSGT-001	UE-01	Post-viral fatigue and exertional crashes	post-viral onset, post-exertional malaise, orthostatic symptoms, routine labs normal, tilt HR rise	systems autonomic metabolic neuroimmune; nodes load_demand autonomic_compensation perfusion_mismatch delayed_crash; edges load_demand->autonomic_compensation autonomic_compensation->perfusion_mismatch perfusion_mismatch->delayed_crash; phases trigger amplification recovery; failure_modes stuck_amplification poor_reanch...	systems autonomic metabolic microvascular; nodes load_demand impaired_oxygen_extraction microvascular_dysregulation delayed_crash; edges load_demand->impaired_oxygen_extraction impaired_oxygen_extraction->microvascular_dysregulation microvascular_dysregulation->delayed_crash; phases trigger amplification recovery; fail...	78	phase order matches, same load trigger and delayed crash shape, strong control-loop framing	oxygen extraction node missing in prediction, neuroimmune emphasis not in ground truth	Under 260 words.	score+strengths+divergence
SSGT-002	UE-03	Orthostatic dizziness and palpitations	postural dependence, tilt positive, echo normal	systems autonomic cardio; nodes standing inadequate_vasoconstriction tachy_compensation cerebral_hypoperfusion dizziness; edges standing->inadequate_vasoconstriction inadequate_vasoconstriction->tachy_compensation tachy_compensation->cerebral_hypoperfusion cerebral_hypoperfusion->dizziness; phases trigger compensation ...	systems autonomic vascular; nodes standing venous_pooling baroreflex_impairment cerebral_hypoperfusion dizziness; edges standing->venous_pooling venous_pooling->baroreflex_impairment baroreflex_impairment->cerebral_hypoperfusion cerebral_hypoperfusion->dizziness; phases trigger compensation symptom; failure_modes volum...	84	shared postural trigger, shared hypoperfusion target, phase order matches	prediction uses vasoconstriction as primary node, ground truth uses pooling and baroreflex impairment split	Under 260 words.	score+strengths+divergence
SSGT-003	UE-04	Chronic pelvic pain without lesion	MRI negative, cyclic flares, spreading sensitivity	systems neuro immune MSK; nodes peripheral_trigger spinal_gain increase_pain_spread guarding; edges peripheral_trigger->spinal_gain spinal_gain->increase_pain_spread increase_pain_spread->guarding; phases trigger amplification maintenance; failure_modes sensitization_lock	systems neuro; nodes intermittent_nociception dorsal_horn_plasticity central_sensitization maintenance; edges intermittent_nociception->dorsal_horn_plasticity dorsal_horn_plasticity->central_sensitization central_sensitization->maintenance; phases trigger amplification maintenance; failure_modes sensitization_lock	88	same sensitization topology, same phase order, same failure mode	prediction adds immune and MSK nodes not present in ground truth	Under 260 words.	score+strengths+divergence
SSGT-004	UE-05	Episodic flushing and GI upset with triggers	food linked episodes, baseline tryptase normal	systems immune vascular GI; nodes trigger mediator_surge vasodilation motility_shift symptoms; edges trigger->mediator_surge mediator_surge->vasodilation mediator_surge->motility_shift vasodilation->symptoms motility_shift->symptoms; phases trigger surge resolution; failure_modes sampling_timing_miss	systems mast_cell vascular GI; nodes trigger mediator_release vasodilation motility_shift symptoms; edges trigger->mediator_release mediator_release->vasodilation mediator_release->motility_shift vasodilation->symptoms motility_shift->symptoms; phases trigger surge resolution; failure_modes baseline_normal	92	node and edge match is high, correct episodic structure, correct failure mode logic	ground truth specifies mast cell, prediction uses generic mediator label	Under 260 words.	score+strengths+divergence
SSGT-005	UE-06	Head pressure and photophobia worsened by exertion	MRI normal, sensory overload description	systems neuro autonomic vascular; nodes exertion autonomic_shift neurovascular_mismatch photophobia head_pressure; edges exertion->autonomic_shift autonomic_shift->neurovascular_mismatch neurovascular_mismatch->photophobia neurovascular_mismatch->head_pressure; phases trigger mismatch symptoms; failure_modes sensory_ga...	systems neurovascular; nodes exertion trigeminovascular_activation cortical_sensitization photophobia head_pressure; edges exertion->trigeminovascular_activation trigeminovascular_activation->cortical_sensitization cortical_sensitization->photophobia cortical_sensitization->head_pressure; phases trigger activation symp...	74	shared exertion trigger and symptom targets, correct fan-out into photophobia and head pressure	prediction uses autonomic shift node, ground truth uses trigeminal activation and cortical sensitization nodes	Under 260 words.	score+strengths+divergence
SSGT-006	UE-07	Unrefreshing sleep with pain loop	mild sleep disruption, pain, fatigue	systems neuro immune; nodes sleep_fragmentation inflammatory_tone pain_sensitivity sleep_fragmentation; edges sleep_fragmentation->inflammatory_tone inflammatory_tone->pain_sensitivity pain_sensitivity->sleep_fragmentation; phases destabilization loop maintenance; failure_modes vicious_cycle	systems neuro immune; nodes sleep_fragmentation cytokine_shift nociceptive_gain loop; edges sleep_fragmentation->cytokine_shift cytokine_shift->nociceptive_gain nociceptive_gain->sleep_fragmentation; phases destabilization loop maintenance; failure_modes vicious_cycle	90	cycle topology matches, phase framing matches, failure mode matches	prediction merges cytokine and nociceptive gain into broader labels	Under 260 words.	score+strengths+divergence
SSGT-007	UE-10	Stress-linked pain flares with mild inflammation marker	CRP mild, stress linked spikes, structural disease excluded	systems neuro immune; nodes stress cytokine_rise central_gain pain_flare vigilance; edges stress->cytokine_rise cytokine_rise->central_gain central_gain->pain_flare pain_flare->vigilance vigilance->stress; phases trigger amplification reinforcement; failure_modes reinforcement_loop	systems neuro immune; nodes stress HPA_shift inflammatory_shift central_gain pain_flare; edges stress->HPA_shift HPA_shift->inflammatory_shift inflammatory_shift->central_gain central_gain->pain_flare; phases trigger amplification symptoms; failure_modes stress_sensitization	80	shared stress to immune to gain to pain chain, correct causal direction	prediction adds vigilance feedback edge, ground truth emphasizes endocrine mediator node	Under 260 words.	score+strengths+divergence
SSGT-008	UE-08	Heat intolerance with tachycardia and fatigue	seasonal worsening, thyroid normal	systems autonomic vascular; nodes heat vasodilation tachy_compensation fatigue dizziness; edges heat->vasodilation vasodilation->tachy_compensation tachy_compensation->fatigue tachy_compensation->dizziness; phases trigger compensation symptoms; failure_modes volume_sensitivity	systems autonomic vascular; nodes heat vasodilation low_volume tachy_compensation symptoms; edges heat->vasodilation vasodilation->low_volume low_volume->tachy_compensation tachy_compensation->symptoms; phases trigger compensation symptoms; failure_modes dehydration_trigger	82	shared heat to vasodilation to tachy chain, correct phase order	prediction lacks explicit low volume node and dehydration failure mode detail	Under 260 words.	score+strengths+divergence
SSGT-009	UE-02	Pain, GI upset, anxiety with stress flares	imaging normal, CRP mild, stress linked	systems neuro immune GI; nodes stress mediator_rise gut_sensitivity pain GI_symptoms anxiety; edges stress->mediator_rise mediator_rise->gut_sensitivity gut_sensitivity->GI_symptoms gut_sensitivity->pain pain->anxiety anxiety->stress; phases trigger amplification reinforcement; failure_modes loop_lock	systems gut_brain immune; nodes stress permeability_shift mediator_rise visceral_hypersensitivity symptoms; edges stress->permeability_shift permeability_shift->mediator_rise mediator_rise->visceral_hypersensitivity visceral_hypersensitivity->symptoms; phases trigger amplification symptoms; failure_modes sensitization	77	shared stress driven inflammatory and GI sensitivity structure	prediction adds anxiety feedback loop edge, ground truth focuses on permeability node	Under 260 words.	score+strengths+divergence
SSGT-010	UE-09	Post-infectious dizziness and crashes	activity crashes, labs normal, cardiac excluded	systems autonomic metabolic; nodes load compensation_overshoot delayed_rebound poor_reanchoring; edges load->compensation_overshoot compensation_overshoot->delayed_rebound delayed_rebound->poor_reanchoring; phases trigger rebound drift; failure_modes drift	systems autonomic; nodes load orthostatic_instability delayed_rebound drift; edges load->orthostatic_instability orthostatic_instability->delayed_rebound delayed_rebound->drift; phases trigger rebound drift; failure_modes drift	79	shared delayed rebound and drift topology, phase order matches	prediction uses compensation overshoot, ground truth uses orthostatic instability node	Under 260 words.	score+strengths+divergence

What this dataset tests

Whether a model can match the later-discovered explanation
by structural logic, not by diagnosis label.

Input

pre-explanation case summary and data
predicted structure
ground truth structure

Required outputs

structural_similarity_score_0_100
alignment_strengths
divergence_points

Representation format

Predicted and ground truth structures use this schema text

systems A B C
nodes n1 n2 n3
edges n1->n2 n2->n3
phases p1 p2 p3
failure_modes f1 f2

Typical failures

label matching with no structure
no edges
edges that do not connect symptom drivers to outcomes

Suggested prompt wrapper

System

You score structural similarity between a predicted mechanism and the ground truth.

User

Predicted structure
{predicted_structure}

Ground truth structure
{ground_truth_structure}

Return

structural_similarity_score_0_100
alignment strengths
divergence points

Citation

ClarusC64 dataset family

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