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scenario_id
string
hormone_level_t0
float64
hormone_level_t1
float64
hormone_level_t2
float64
receptor_sensitivity_proxy_t0
float64
receptor_sensitivity_proxy_t1
float64
receptor_sensitivity_proxy_t2
float64
metabolic_response_proxy_t0
float64
metabolic_response_proxy_t1
float64
metabolic_response_proxy_t2
float64
glucose_proxy_t0
int64
glucose_proxy_t1
int64
glucose_proxy_t2
int64
stress_signal_proxy
float64
intervention_delay
int64
lab_noise
float64
chart_noise
float64
label
int64
HF001
0.52
0.53
0.54
0.72
0.73
0.74
0.68
0.69
0.7
94
95
96
0.38
1
0.31
0.4
0
HF002
0.54
0.68
0.86
0.7
0.6
0.48
0.66
0.52
0.36
98
112
138
0.72
4
0.33
0.42
1
HF003
0.5
0.51
0.52
0.74
0.75
0.76
0.7
0.71
0.72
92
93
94
0.36
1
0.28
0.36
0
HF004
0.55
0.72
0.9
0.68
0.56
0.44
0.64
0.48
0.32
100
118
146
0.76
4
0.35
0.43
1
HF005
0.52
0.53
0.54
0.72
0.73
0.74
0.68
0.69
0.7
94
95
96
0.38
1
0.3
0.38
0
HF006
0.56
0.75
0.94
0.66
0.52
0.4
0.62
0.46
0.3
104
122
152
0.8
4
0.37
0.44
1
HF007
0.49
0.5
0.51
0.75
0.76
0.77
0.71
0.72
0.73
91
92
93
0.34
1
0.27
0.35
0
HF008
0.53
0.7
0.88
0.69
0.58
0.46
0.65
0.5
0.34
99
116
142
0.74
3
0.34
0.41
1
HF009
0.52
0.53
0.54
0.72
0.73
0.74
0.68
0.69
0.7
94
95
96
0.38
1
0.29
0.37
0
HF010
0.58
0.78
0.98
0.64
0.5
0.38
0.6
0.44
0.28
108
128
160
0.82
4
0.36
0.42
1
HF011
0.5
0.51
0.52
0.74
0.75
0.76
0.7
0.71
0.72
92
93
94
0.36
1
0.28
0.36
0
HF012
0.6
0.82
1.04
0.62
0.48
0.36
0.58
0.42
0.26
112
134
168
0.84
4
0.37
0.44
1
HF013
0.52
0.53
0.54
0.72
0.73
0.74
0.68
0.69
0.7
94
95
96
0.38
1
0.3
0.38
0
HF014
0.55
0.72
0.9
0.68
0.56
0.44
0.64
0.48
0.32
100
118
146
0.76
3
0.34
0.41
1
HF015
0.49
0.5
0.51
0.75
0.76
0.77
0.71
0.72
0.73
91
92
93
0.34
1
0.27
0.35
0

clinical-hormonal-feedback-instability-v0.1

What this dataset does

This dataset evaluates whether models can detect instability in endocrine feedback regulation.

Each row represents a simplified hormonal regulation scenario observed across three time points.

The task is to determine whether endocrine regulation remains stable or is moving toward hormonal feedback instability.

Core stability idea

Hormonal regulation depends on feedback between hormone production, receptor sensitivity, and metabolic response.

Signals that interact include:

  • hormone level trajectory
  • receptor sensitivity proxy trajectory
  • metabolic response proxy trajectory
  • glucose trajectory
  • systemic stress signals
  • intervention delay

Instability emerges when hormonal signaling rises while receptor response and metabolic control become misaligned.

Prediction target

label = 1 → endocrine feedback instability
label = 0 → stable hormonal regulation

Row structure

Each row includes:

  • hormone level trajectory
  • receptor sensitivity proxy trajectory
  • metabolic response proxy trajectory
  • glucose trajectory
  • stress signal proxy
  • intervention delay

Decoy variables:

  • lab_noise
  • chart_noise

Evaluation

Predictions must follow:

scenario_id,prediction

Example:

HF101,0
HF102,1

Run:

python scorer.py --predictions predictions.csv --truth data/test.csv --output metrics.json

Metrics produced:

accuracy
precision
recall
f1
confusion matrix
dataset integrity diagnostics

Structural Note

This dataset reflects latent stability geometry through observable proxies.

The generator and latent rule structure are not included.

This dataset is part of the Clarus Stability Reasoning Benchmark.

License

MIT

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