Datasets:

ClarusC64
/

ABX-HT-004_qt_prolongation_prediction-v0.1

row_id string	series_id string	timepoint_h int64	host_model string	drug string	drug_conc_ng_mL int64	expected_drug_conc_ng_mL int64	conc_deviation int64	qtc_ms int64	expected_qtc_ms int64	qtc_rise_vs_expected_ms int64	cardiac_coherence_index float64	exposure_index float64	stress_index float64	later_serious_arrhythmia_flag int64	assay_method string	source_type string	qt_risk_signal int64	earliest_qt_risk int64	notes string
ABXHT004-TR-0001	S1	0	human_sim	azithromycin	80	80	0	410	410	0	0.9	0.1	0.1	0	ecg_pk_panel	simulated	0	0	baseline
ABXHT004-TR-0002	S1	6	human_sim	azithromycin	120	120	0	415	415	0	0.88	0.85	0.9	0	ecg_pk_panel	simulated	0	0	tracks expected
ABXHT004-TR-0003	S1	12	human_sim	azithromycin	125	120	5	450	420	30	0.35	0.9	0.9	0	ecg_pk_panel	simulated	0	0	first decoupling
ABXHT004-TR-0004	S1	18	human_sim	azithromycin	130	120	10	460	420	40	0.3	0.9	0.9	0	ecg_pk_panel	simulated	1	1	confirmed onset
ABXHT004-TR-0005	S1	48	human_sim	azithromycin	140	125	15	520	425	95	0.2	0.9	0.9	1	ecg_pk_panel	simulated	1	0	arrhythmia later
ABXHT004-TR-0006	S2	0	human_sim	levofloxacin	90	90	0	405	405	0	0.9	0.1	0.1	0	ecg_pk_panel	simulated	0	0	baseline
ABXHT004-TR-0007	S2	12	human_sim	levofloxacin	110	110	0	410	410	0	0.86	0.9	0.9	0	ecg_pk_panel	simulated	0	0	stable
ABXHT004-TR-0008	S2	24	human_sim	levofloxacin	110	110	0	412	412	0	0.84	0.9	0.9	0	ecg_pk_panel	simulated	0	0	stable
ABXHT004-TR-0009	S3	0	human_sim	azithromycin	120	120	0	490	490	0	0.9	0.9	0.9	1	ecg_pk_panel	simulated	0	0	baseline QTc high
ABXHT004-TR-0010	S4	0	human_sim	azithromycin	130	120	10	460	420	40	0.3	0.9	0.3	1	ecg_pk_panel	simulated	0	0	stress low

ABX-HT-004 QT Prolongation Prediction

Purpose

Detect early QT risk when cardiac repolarization markers stop tracking drug levels before serious arrhythmia events.

Core pattern

Files

Schema

Each row is one timepoint in a within series time course.

Required columns

Labels

Scorer logic in v1

Evaluation

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