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row_id
string
series_id
string
day
int64
host_model
string
abx_drug
string
abx_exposure_index
float64
host_stress_index
float64
symptom_score
int64
expected_symptom_score
int64
symptom_nonresponse_vs_expected
int64
urine_culture_cfu_mL
int64
expected_urine_cfu_mL
int64
urine_cfu_persistence_vs_expected
int64
urine_leukocyte_esterase
int64
expected_leukocyte_esterase
int64
le_nonresponse_vs_expected
int64
uti_coherence_index
float64
later_uti_recurrence_flag
int64
assay_method
string
source_type
string
uti_recurrence_risk_signal
int64
earliest_uti_recurrence_risk
int64
notes
string
ABXCS003-TR-0001
S1
0
human_sim
nitrofurantoin
0.1
0.2
8
8
0
100,000
100,000
0
3
3
0
0.9
0
urine_panel
simulated
0
0
baseline
ABXCS003-TR-0002
S1
2
human_sim
nitrofurantoin
0.9
0.9
5
5
0
12,000
15,000
-3,000
2
2
0
0.86
0
urine_panel
simulated
0
0
tracks expected
ABXCS003-TR-0003
S1
3
human_sim
nitrofurantoin
0.9
0.9
5
3
2
20,000
5,000
15,000
2
1
1
0.35
0
urine_panel
simulated
0
0
first coherence loss
ABXCS003-TR-0004
S1
4
human_sim
nitrofurantoin
0.9
0.9
5
2
3
18,000
1,500
16,500
2
1
1
0.3
0
urine_panel
simulated
1
1
onset
ABXCS003-TR-0005
S1
14
human_sim
nitrofurantoin
0.9
0.9
6
0
6
80,000
0
80,000
3
0
3
0.2
1
urine_panel
simulated
1
0
recurrence later
ABXCS003-TR-0006
S2
0
human_sim
trimethoprim
0.1
0.2
7
7
0
80,000
80,000
0
3
3
0
0.9
0
urine_panel
simulated
0
0
baseline
ABXCS003-TR-0007
S2
3
human_sim
trimethoprim
0.9
0.8
2
2
0
1,000
1,500
-500
0
1
-1
0.84
0
urine_panel
simulated
0
0
clearing
ABXCS003-TR-0008
S2
7
human_sim
trimethoprim
0.9
0.8
0
0
0
0
0
0
0
0
0
0.83
0
urine_panel
simulated
0
0
resolved
ABXCS003-TR-0009
S3
0
human_sim
nitrofurantoin
0.9
0.9
1
1
0
100,000
100,000
0
3
3
0
0.9
1
urine_panel
simulated
0
0
symptoms low baseline
ABXCS003-TR-0010
S4
4
human_sim
nitrofurantoin
0.3
0.9
5
2
3
18,000
1,500
16,500
2
1
1
0.3
1
urine_panel
simulated
0
0
exposure low

ABX-CS-003 UTI Recurrence Prediction

Purpose

Predict UTI recurrence from early coherence loss during treatment.

Core pattern

  • host_stress_index high
  • abx_exposure_index high
  • uti_coherence_index drops
  • urine_cfu_persistence_vs_expected stays high
  • symptom_nonresponse_vs_expected stays high
  • later_uti_recurrence_flag appears

Files

  • data/train.csv
  • data/test.csv
  • scorer.py

Schema

Each row is one timepoint in a within series UTI course.

Required columns

  • row_id
  • series_id
  • day
  • host_model
  • abx_drug
  • abx_exposure_index
  • host_stress_index
  • symptom_score
  • expected_symptom_score
  • symptom_nonresponse_vs_expected
  • urine_culture_cfu_mL
  • expected_urine_cfu_mL
  • urine_cfu_persistence_vs_expected
  • urine_leukocyte_esterase
  • expected_leukocyte_esterase
  • le_nonresponse_vs_expected
  • uti_coherence_index
  • later_uti_recurrence_flag
  • assay_method
  • source_type
  • uti_recurrence_risk_signal
  • earliest_uti_recurrence_risk

Labels

  • uti_recurrence_risk_signal

    • 1 for rows at or after first confirmed risk onset
  • earliest_uti_recurrence_risk

    • 1 only for the first onset row in that series

Scorer logic in v1

  • exclude series where baseline symptoms are already low
  • candidate onset point
    • abx_exposure_index at least 0.80
    • host_stress_index at least 0.80
    • uti_coherence_index at most 0.40
    • urine_cfu_persistence_vs_expected at least 12000
    • symptom_nonresponse_vs_expected at least 2.0
    • for two consecutive points
    • ignore one point contamination spike then clean
  • confirmation
    • later_uti_recurrence_flag equals 1 later in series

Evaluation

Run

  • python scorer.py --path data/test.csv
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