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3,421,000 | Photocatalytic Nanocomposite Polymer-TiO2 Membranes for Pollutant Removal from WastewaterMorphology of polyvinylidene fluoride and its blend in thermally induced phase separation process. X Li, X Lu, 10.1002/app.23489J. Appl. Polym. Sci. 101Li, X.; Lu, X. Morphology of polyvinylidene fluoride and its blend in thermally... |
3,421,001 | Photocatalytic Nanocomposite Polymer-TiO2 Membranes for Pollutant Removal from WastewaterSolvothermal-induced assembly of 2D-2D rGO-TiO2 nanocomposite for the construction of nanochannel membrane. J Yu, Y Zhang, J Chen, L Cui, W Jing, 10.1016/j.memsci.2020.117870J. Membr. Sci. 2020Yu, J.; Zhang, Y.; Chen, J.; Cui, L.; ... |
3,421,002 | Photocatalytic Nanocomposite Polymer-TiO2 Membranes for Pollutant Removal from WastewaterEvaluation of performance of hybrid photolysis-DCMD and photocatalysis-DCMD systems utilizing UV-C radiation for removal of diclofenac sodium salt from water. S Mozia, D Darowna, J Przepiórski, A W Morawski, 10.2478/pjct-2013-0010P... |
3,421,003 | Photocatalytic Nanocomposite Polymer-TiO2 Membranes for Pollutant Removal from WastewaterDesign of high efficiency PVDF-PEG hollow fibers for air filtration of ultrafine particles. L Wang, W F Yong, L E Yu, T Chung, 10.1016/j.memsci.2017.04.053J. Membr. Sci. 535Wang, L.; Yong, W.F.; Yu, L.E.; Chung, T. Design of high e... |
3,421,004 | Photocatalytic Nanocomposite Polymer-TiO2 Membranes for Pollutant Removal from WastewaterInfluence of type and position of functional groups of phenolic compounds on NF/RO performance. J M Arsuaga, A Sotto, M J López-Muñoz, L Braeken, 10.1016/j.memsci.2011.02.020J. Membr. Sci. 372Arsuaga, J.M.; Sotto, A.; López-Muñoz, ... |
3,421,005 | Photocatalytic Nanocomposite Polymer-TiO2 Membranes for Pollutant Removal from WastewaterPhotocatalytic degradation of dyes by using a membrane reactor. R Molinari, F Pirillo, M Falco, V Loddo, L Palmisano, 10.1016/j.cep.2004.01.008Chem. Eng. Process. 43Molinari, R.; Pirillo, F.; Falco, M.; Loddo, V.; Palmisano, L. Pho... |
3,421,006 | Photocatalytic Nanocomposite Polymer-TiO2 Membranes for Pollutant Removal from WastewaterPreparation and characterization of TiO2-PVDF/PMMA blend membranes using an alternative non-toxic solvent for UF/MF and photocatalytic application. O Benhabiles, F Galiano, T Marino, H Mahmoudi, H Lounici, A Figoli, 10.3390/molecul... |
3,421,007 | Effects of Different LED Light Qualities on Growth and Chlorophyll Fluorescence Parameters in Planting Virus-Free Potato by Hydroponics SystemEffects of Different LED Light Qualities on Growth and Chlorophyll Fluorescence Parameters in Planting Virus-Free Potato by Hydroponics System
2018. 2018
Yuqiao Tang
High Schoo... |
3,421,008 | Effects of Different LED Light Qualities on Growth and Chlorophyll Fluorescence Parameters in Planting Virus-Free Potato by Hydroponics SystemHans Journal of Agricultural Sciences 农业科学
8122018. 201810.12677/hjas.2018.812214Received: Dec. 4 th , 2018; accepted: Dec. 14 th , 2018; published: Dec. 21 st , 2018Published On... |
3,421,009 | Effects of Different LED Light Qualities on Growth and Chlorophyll Fluorescence Parameters in Planting Virus-Free Potato by Hydroponics System叶绿素是植物进行光合作用重要的物质基础。如表 1 所示，不同光质处理的两个马铃薯品种叶绿素 含量均表现为：R > 7R1B > 3R1B > 1R1B > 1R3B > 1R7B > B，且 R 和 7R1B 处理下的叶绿素含量显著高 于对照 W；叶绿素 a/b 值：B > 1R7B > 1R3B > 1R1B > 3R1B ≥ 7R1B ≥ R，且 R... |
3,421,010 | Effects of Different LED Light Qualities on Growth and Chlorophyll Fluorescence Parameters in Planting Virus-Free Potato by Hydroponics System致[29]，红光/蓝光值与叶绿素含量高低呈正比；红光可降低叶片 Chl a/b 值，蓝光可提高叶片 Chl a/b 值， 而蓝光增加到一定比例时 Chl a/b 无显著变化，说明蓝光只能在一定范围内提高 Chl a/b。叶绿素 a 含量 Chl a (mg•g −1 FW) 叶绿素 b 含量 Chl b (mg•g −1 FW) 叶绿素总含量 Chl a... |
3,421,011 | Effects of Different LED Light Qualities on Growth and Chlorophyll Fluorescence Parameters in Planting Virus-Free Potato by Hydroponics System1 . |
3,421,012 | Effects of Different LED Light Qualities on Growth and Chlorophyll Fluorescence Parameters in Planting Virus-Free Potato by Hydroponics System1引言 CRY1 使胚轴生长抑制；而 CRY2 仅仅位于细胞核中，具有促进开花和抑制胚轴延长的作用[4]。大多数 马铃薯栽培种的开花和块茎形成受光周期调控[5]，而感受光周期变化的光受体就是 Phy 和 Cry [6]。前人 已在番茄[7]、萝卜[8]、菠菜[9]、生姜[10]、草莓[11]、彩色甜椒[12]、莴苣[13]、青蒜苗[14]、黄瓜[15]、... |
3,421,013 | Effects of Different LED Light Qualities on Growth and Chlorophyll Fluorescence Parameters in Planting Virus-Free Potato by Hydroponics SystemA 病毒和癌肿病免疫；鲜薯干物质含量 17.7%，淀粉含量 12.4%，还原糖含 试验光源仅采用 LED 灯，每小区设置 10 根长为 120 cm 的 LED 灯管，各小区间的灯架上方和四周 悬挂银灰色挡光帘幕， 以阻挡外界自然光。 处理前利用 Li-1400 数据采集器链接辐射传感器(美国 Li-COR)光是植物生长最重要的环境因子，是能量的主要来源... |
3,421,014 | Effects of Different LED Light Qualities on Growth and Chlorophyll Fluorescence Parameters in Planting Virus-Free Potato by Hydroponics System质代谢、内源激素水平以及基因表达等方面均具有调控作用；已有研究证明，红蓝组合光可满足多种蔬
菜植物的正常生长发育， 植物对红蓝光的吸收率能达到 90%， 因此红蓝光是植物生理活动的主要光源[1]。
光形态建成传感信息的三个主要光感受器：光敏色素(phytochrome)，蓝色光感受器，和 UV-B 光感受器。
光敏色素吸收红光及远红光区域的光... |
3,421,015 | Effects of Different LED Light Qualities on Growth and Chlorophyll Fluorescence Parameters in Planting Virus-Free Potato by Hydroponics System马铃薯受病毒侵染并逐代积累减产严重[20]，因此世界科学家主要采用脱毒马铃薯生产，其主要的四
种离体结薯途径(大田土壤基质生产、无土基质生产、试管直接诱导微型薯和水培栽培生产)生产无病毒种
薯过程中，水培栽培是新型的栽培方式，受到众多国内外的马铃薯专家所推崇。但迄今为止，对其他三
种繁育方式的块茎发育机理的研究已有诸多报道，对水培栽培结薯的生... |
3,421,016 | Effects of Different LED Light Qualities on Growth and Chlorophyll Fluorescence Parameters in Planting Virus-Free Potato by Hydroponics System试验于 2016 年 9 月~2017 年 2 月在西南大学薯类作物研究所马铃薯水培温室进行。供试脱毒马铃薯
品种为费乌瑞它(Favorite，简写 FN)和鄂薯 5 号(Eshu 5，简写 ES5)。
费乌瑞它马铃薯由荷兰引进，早熟马铃薯品种，生育期 65 天。植株生长势强，株型直立，分枝少，
株高 65 cm 左右，茎带紫褐色网状花纹；叶... |
3,421,017 | Effects of Different LED Light Qualities on Growth and Chlorophyll Fluorescence Parameters in Planting Virus-Free Potato by Hydroponics System植株整齐，茎叶绿色，叶片较小；花冠白色，开花繁茂；匍匐茎短，结薯集中，块茎长扁形，表皮光滑，
黄皮、白肉，芽眼浅；植株高抗马铃薯 X 病毒病、抗马铃薯 Y 病毒病，抗晚疫病；干物质含量 22.7%，
淀粉含量 14.5%，还原糖含量 0.22%，粗蛋白含量 1.88%，维生素 C 含量 16.6 毫克/100 克。其脱毒试管
苗由西南大学薯类... |
3,421,018 | Effects of Different LED Light Qualities on Growth and Chlorophyll Fluorescence Parameters in Planting Virus-Free Potato by Hydroponics System试验光源选用上海鼎铎照明电器有限公司生产的 KD-LED-T5 灯管，每只灯管长 120 cm，包含 92 颗
蓝色(主要波长范围 400~500 nm,， 波峰 460 nm)或红色(主要波长范围 610~710 nm， 波峰 660 nm)或白色(主
要波长范围 400~800 nm，波峰 450 nm 和 560 nm)的贴片，灯珠按照试验... |
3,421,019 | Effects of Different LED Light Qualities on Growth and Chlorophyll Fluorescence Parameters in Planting Virus-Free Potato by Hydroponics System2℃，湿度保持在 70%~90%。水培采用营养液膜技术(NFT)，营养液为改进的霍格兰营养液，pH 值为 5.8
± 0.2。水和营养液通过喷头装置自动控制。待植株生长 20 天根系发达后，在栽培板下架设特制支架，将
栽培板撑起 5 cm，保证有充足结薯空间。栽培槽底前期保持 2~3 cm 营养液膜，中后期降至 1 cm 左右，
保证根与空气... |
3,421,020 | Effects of Different LED Light Qualities on Growth and Chlorophyll Fluorescence Parameters in Planting Virus-Free Potato by Hydroponics System在光质处理 20 d 时各小区随机选取三株植株进行拍照记录，并测定根长，采用剪纸称重法测量叶面
积，用精确度为 0.001 g 的天平测定叶、茎、根鲜重及干重(在烘干箱内用 105℃杀青 30 min，80℃烘至恒
重)；小区内连续 10 株对叶片数计数；用游标卡尺测量茎粗(量近基部最粗处的茎的直径的平均值)和倒四
叶的叶片纵、横径；用直尺测... |
3,421,021 | Effects of Different LED Light Qualities on Growth and Chlorophyll Fluorescence Parameters in Planting Virus-Free Potato by Hydroponics System乙醇:丙酮 = 2:1 的混合提取液中，密封黑暗放置 48 h 后，645 nm、663 nm、470 nm 三波段下测吸光值。
叶绿素 a 的浓度(mg/L)：Ca = 12.21A663 -2.81A645
叶绿素 b 的浓度(mg/L)：Cb = 20.13A645 -5.03A663
类胡萝卜素(mg/L)：Cx = (1000A47... |
3,421,022 | Effects of Different LED Light Qualities on Growth and Chlorophyll Fluorescence Parameters in Planting Virus-Free Potato by Hydroponics System3. 结果与分析
3.1. 不同光质下马铃薯叶片叶绿素和类胡萝卜素含量
Table 1 .
1Effect of different light qualities on chlorophyll and caroteniod content in potato leaves at stolon development stage 表 1. 不... |
3,421,023 | Effects of Different LED Light Qualities on Growth and Chlorophyll Fluorescence Parameters in Planting Virus-Free Potato by Hydroponics SystemTable 2 . |
3,421,024 | Effects of Different LED Light Qualities on Growth and Chlorophyll Fluorescence Parameters in Planting Virus-Free Potato by Hydroponics System2光质处理的费乌瑞它的壮苗指数与 W 无显著差异，依次为 3R1B > B > W > 1R7B > 1R3B；红光与蓝光处 7R1B > 1R7B > 3R1B > 1R3B > 1R1B； 3R1B 和蓝光处理下幼苗的茎粗与对照无显著差异， 依次是 B > W > 3R1B；蓝光处理的幼苗的鲜样质量和干样质量均显著高于对照，所有处理下植株鲜样质量或干... |
3,421,025 | Effects of Different LED Light Qualities on Growth and Chlorophyll Fluorescence Parameters in Planting Virus-Free Potato by Hydroponics System> 1R3B > 1R7B > 7R1B；两品种的叶片含水量一致的表现是：1R1B > 7R1B > 3R1B > 1R7B > R、B，1R3B 的植株茎粗较大，红光以及 R7B1 下的幼苗植株茎粗较小，说明蓝光和适宜比例的红蓝组合光才能对植 株的茎粗有促进作用，与蒲高斌[7]、曹刚[29]、苏娜娜[30]、刘媛[31]、Poudel [32]、Bar... |
3,421,026 | Effects of Different LED Light Qualities on Growth and Chlorophyll Fluorescence Parameters in Planting Virus-Free Potato by Hydroponics System[37] [38]。红光下的类胡萝卜 素含量最高，其次是 R1B3，蓝光下的类胡萝卜素含量较低，说明类胡萝卜素含量不是简单的随红/蓝光 值变化。红光及 R7B1 光质下的叶片叶绿素含量显著高于对照，但 Chl a/b 值显著低于对照白光；R3B1 处理下的叶绿素、类胡萝卜素含量和 Chl a/b 值均与对照白光无显著差异。 4.3. 不同光质对马铃薯叶片... |
3,421,027 | Effects of Different LED Light Qualities on Growth and Chlorophyll Fluorescence Parameters in Planting Virus-Free Potato by Hydroponics System次之，与刘庆[38]在草莓上的研究结果一致。 本研究中，各处理的 Fv/Fm 较为稳定，除 10 d 外均在 0.8~0.85 之间，R7B1、R3B1 和纯蓝光下各个 时期 FN 的 Fv/Fm 均处于较高水平，R1B3 和 R1B7 处理的 Fv/Fm 处于较低状态，Fv/Fm 未大幅度降低， 说明马铃薯受光抑制程度不显著，PSII 反应中心都没有受... |
3,421,028 | Effects of Different LED Light Qualities on Growth and Chlorophyll Fluorescence Parameters in Planting Virus-Free Potato by Hydroponics System和 R1B7 处理下叶片的 PSII 功能良好。各个时 期，红光处理下的 Φ PSII 、qP 和 ETR 一直处于较低水平，而非光化学淬灭系数 qN 保持在较高水平，说明 红光下植株吸收的光能大多以热的形式散掉， 这与曹刚[29]研究的红光处理下黄瓜的 NPQ 比蓝光处理高， 认为红光处理下叶片吸收的光能大多以热的形式耗散掉结果一致。 5. 结论 不同... |
3,421,029 | Effects of Different LED Light Qualities on Growth and Chlorophyll Fluorescence Parameters in Planting Virus-Free Potato by Hydroponics SystemR1B7 处理下的植株具有较高的株高、茎粗、干重及壮苗指数， 且提高了 Φ PSII 、ETR 和 qP，产量也较高，但结薯数相对较少，蓝光有利于块茎的膨大，而不利于匍匐茎 的大量产生，所以可通过前期提高红光比例增加匍匐茎的形成，而后期降低红/蓝光比值促进块茎的形成， 从而提高产量。 基金项目 重 庆 市 应 用 开 发 重 点 项 目 ， 马 铃 薯 ... |
3,421,030 | Effects of Different LED Light Qualities on Growth and Chlorophyll Fluorescence Parameters in Planting Virus-Free Potato by Hydroponics SystemW
2.10 deCDE
0.57 efDEF
2.67 efDEF
3.65 bcABC
0.42 deCDE
R
2.89 aA
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3R1... |
3,421,031 | Effects of Different LED Light Qualities on Growth and Chlorophyll Fluorescence Parameters in Planting Virus-Free Potato by Hydroponics System1R3B
1.90 fgEF
0.52 ghiEFGH
2.42 iGH
3.66 bcABC
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2.42 iGH
3.77 abAB
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B
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2.44 hiGH
3.77 abAB... |
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The Cryptochrome Blue Light Receptors. The Arabidopsis Book. X Yu, H Liu, Klejnot, American Society of Plant Bi... |
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3,421,036 | Effects of Different LED Light Qualities on Growth and Chlorophyll Fluorescence Parameters in Planting Virus-Free Potato by Hydroponics SystemEffects of Light Quality on CO 2 Assimilation, Chlorophyll-Fluorescence Quenching, Expression of Calvin Cycle Genes and Carbohydrate Accumulation in Cucumis Sativus. W Hong, G Mi... |
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3,421,039 | Effects of Different LED Light Qualities on Growth and Chlorophyll Fluorescence Parameters in Planting Virus-Free Potato by Hydroponics System. 张国斌 曹刚, 马彦霞 郁继华, 不同光质, 光源对黄瓜苗期生长及叶绿素荧光参数的影响, 曹刚, 张国斌, 郁继华, 马彦霞. 不同光质 LED 光源对黄瓜苗期生长及叶绿素荧光参数的影响[J].
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3,421,040 | Effects of Different LED Light Qualities on Growth and Chlorophyll Fluorescence Parameters in Planting Virus-Free Potato by Hydroponics SystemEffect of Red-and Blue-Light-Emitting Diodes on Growth and Morphogenesis of Grapes. Plant Cell, Tissue and Organ Culture. R Poudelp, I Kataoka, R Mochioka, 10.1007/s11240-007-931... |
3,421,041 | Effects of Different LED Light Qualities on Growth and Chlorophyll Fluorescence Parameters in Planting Virus-Free Potato by Hydroponics System. 植物生 理学报, 47植物生 理学报, 2011, 47(5): 512-520.
. 刘世琦 陈祥伟, 王越, 冯磊 刘景凯, 不同, 光源对乌塌菜生长、光合特性及营养品质的影响, 陈祥伟, 刘世琦, 王越, 刘景凯, 冯磊. 不同 LED 光源对乌塌菜生长、光合特性及营养品质的影响[J].
. 应用生态 学报, 25应用生态 学报, 2014... |
3,421,042 | HDAC and MAPK/ERK Inhibitors Cooperate To Reduce Viability and Stemness in MedulloblastomaHDAC and MAPK/ERK Inhibitors Cooperate To Reduce Viability and Stemness in Medulloblastoma |
3,421,043 | HDAC and MAPK/ERK Inhibitors Cooperate To Reduce Viability and Stemness in MedulloblastomaMariane Da Cunha Jaeger
Eduarda Chiesa Ghisleni
Paula Schoproni Cardoso
Marialva Siniglaglia
Tiago Falcon
André T Brunetto
Algemir L Brunetto
Caroline Brunetto De Farias
Michael D Taylor
Carolina Nör
Vijay Ramaswamy
Raf... |
3,421,044 | HDAC and MAPK/ERK Inhibitors Cooperate To Reduce Viability and Stemness in MedulloblastomaIntroduction
Medulloblastoma (MB), the most common malignant pediatric brain tumor, likely arises from genetic and epigenetics abnormalities during cerebellar development (Wang and Wechsler-Reya 2014;Vladoiu et al. 2019). Integra... |
3,421,045 | HDAC and MAPK/ERK Inhibitors Cooperate To Reduce Viability and Stemness in MedulloblastomaAccording to the cancer stem cell (CSC) hypothesis, recurrence and metastasis in some tumor types may arise from a specific tumor cell subpopulation, the CSC, a distinct population of cells presenting stem cell-like properties suc... |
3,421,046 | HDAC and MAPK/ERK Inhibitors Cooperate To Reduce Viability and Stemness in MedulloblastomaGiven that a failure in maturation of cerebellar progenitor cells is likely at the origin of MB, and the resistance characteristics presented by CSCs may be responsible for therapeutic failure, modulation of cellular differentiati... |
3,421,047 | HDAC and MAPK/ERK Inhibitors Cooperate To Reduce Viability and Stemness in MedulloblastomaTaking into account that the stemness phenotype is proposed as a poor prognostic marker in many cancer types including MB (Glinsky et al. 2005;Shats et al. 2011), and the effects of HDACi in regulating stemness are still not fully... |
3,421,048 | HDAC and MAPK/ERK Inhibitors Cooperate To Reduce Viability and Stemness in MedulloblastomaHistone H3 Acetylation
Cells treated for 48 h with NaB were lysed with a lysis solution buffer and acetylation of H3 was measured with PathScan® Acetylated Histone H3 Sandwich enzyme-linked immunosorbent assay (ELISA) Kit (Cell S... |
3,421,049 | HDAC and MAPK/ERK Inhibitors Cooperate To Reduce Viability and Stemness in MedulloblastomaThe mRNA expression of stemness markers was analyzed by RT-qPCR. Total RNA was extracted from MB cells using SV Total RNA Isolation System kit (Promega, Madison, USA), in accordance with the manufacturer's instructions and quantif... |
3,421,050 | HDAC and MAPK/ERK Inhibitors Cooperate To Reduce Viability and Stemness in MedulloblastomaNeurosphere Formation
Neurosphere formation was used as an established experimental assay to evaluate cancer stem cell proliferation (Nör et al. 2013;Zanini et al. 2013). Daoy and D283 cells were dissociated with trypsin-EDTA int... |
3,421,051 | HDAC and MAPK/ERK Inhibitors Cooperate To Reduce Viability and Stemness in MedulloblastomaDirect cell quantification after 48-h treatment with escalating doses of NaB confirmed a significant reduction in cell viability of both Daoy and D283 relative to vehicle. Consistently with a previous report (Nör et al. 2013), Dao... |
3,421,052 | HDAC and MAPK/ERK Inhibitors Cooperate To Reduce Viability and Stemness in MedulloblastomaTo elucidate whether NaB could suppress MB viability by modulating the stemness phenotype, expression of BMI1 and CD133 was analyzed after 48 h of NaB treatment. Both marks are expressed in all molecular subgroups of MB as observe... |
3,421,053 | HDAC and MAPK/ERK Inhibitors Cooperate To Reduce Viability and Stemness in MedulloblastomaThe reduction in protein levels of BMI1 was confirmed after 24 h of NaB treatment in both cell lines at any dose capable of significantly impairing cell viability. After a 48-h Cavalli et al. (30). b Relative mRNA levels of stemn... |
3,421,054 | HDAC and MAPK/ERK Inhibitors Cooperate To Reduce Viability and Stemness in Medulloblastomafound in D283 cells treated with the highest dose (5 mM) compared to controls (p = 0.0023) (Fig. 2c). |
3,421,055 | HDAC and MAPK/ERK Inhibitors Cooperate To Reduce Viability and Stemness in MedulloblastomaMAPK/ERK signaling regulates normal CNS development. The enrichment analysis of genes significantly correlated with CD133 or BMI1 expression in MB tumor samples from patients showed MAPK signaling or associated pathways (such as n... |
3,421,056 | HDAC and MAPK/ERK Inhibitors Cooperate To Reduce Viability and Stemness in MedulloblastomaGiven that there is a possible relationship between the stemness phenotype and cell viability, cell counting after treatment with U0126 with or without NaB was performed. U0126 (25 μM) significantly reduced MB cell viability (Daoy... |
3,421,057 | HDAC and MAPK/ERK Inhibitors Cooperate To Reduce Viability and Stemness in MedulloblastomaA neurosphere assay was performed to investigate the formation of MB CSCs. First, the mRNA expression of CD133 and BMI1 was measured to confirm enrichment of stemness after sphere formation. Expression of both markers was increase... |
3,421,058 | HDAC and MAPK/ERK Inhibitors Cooperate To Reduce Viability and Stemness in MedulloblastomaWe have previously shown responsiveness of human MB cells and putative MB CSCs to NaB (Nör et al. 2013). Here, we used the same compound to investigate the influence of HDAC inhibition on maintenance of a stemness phenotype of MB.... |
3,421,059 | HDAC and MAPK/ERK Inhibitors Cooperate To Reduce Viability and Stemness in MedulloblastomaExpression of CD133 and BMI1 was significantly decreased after NaB treatment. CD133, also called Prominin-1, is the most used marker to isolate and to identify brain tumor CSCs (Schonberg et al. 2014). BMI1 is a polycomb group pro... |
3,421,060 | HDAC and MAPK/ERK Inhibitors Cooperate To Reduce Viability and Stemness in MedulloblastomaWe observed a decrease in phosphorylated ERK (pERK) in MB cells after NaB treatment. Components of the ERK pathway are upregulated in metastatic MB, and pharmacological inhibition of ERK decreases migration of MB cells (MacDonald ... |
3,421,061 | HDAC and MAPK/ERK Inhibitors Cooperate To Reduce Viability and Stemness in MedulloblastomaIn MB, Chow et al. (2014) showed differential ERK signaling activation and neurosphere formation capability in MB cells from spontaneous tumors obtained from patched (Ptch)+/− mice. Tumors that were able to form neurospheres indep... |
3,421,062 | HDAC and MAPK/ERK Inhibitors Cooperate To Reduce Viability and Stemness in MedulloblastomaACTB
5′-AAA CTG GAA CGG TGA AGG TG -3′ 5′-AGA GAA GTG GGG TGG CTT TT -3′ BMI1 5′-TGC TTT GTG GAG GGT ACT TC -3′ 5′-GTC TGG TCT TGT GAA CTT GGA -3′ CD133 5′-GGC AAA TCA CCA GGT AAG AAC -3′ 5′-AAC GCC TTG TCC TTG GTA G -3′
Fig. 2
2... |
3,421,063 | HDAC and MAPK/ERK Inhibitors Cooperate To Reduce Viability and Stemness in MedulloblastomaR.R.); the Coordination for the Improvement of Higher Education Personnel (CAPES); and the Clinical Hospital institutional research fund (FIPE/HCPA). T.F. is supported by Programa Nacional de Pós-Doutorado (PNPD, CAPES/HCPA, Grant... |
3,421,064 | HDAC and MAPK/ERK Inhibitors Cooperate To Reduce Viability and Stemness in MedulloblastomaThe role of PI3K/AKT, MAPK/ERK and NF kappa beta signalling in the maintenance of human embryonic stem cell pluripotency and viability highlighted by transcriptional profiling and functional analysis. L Armstrong, O Hughes, S Yung... |
3,421,065 | HDAC and MAPK/ERK Inhibitors Cooperate To Reduce Viability and Stemness in Medulloblastoma. Fmg Cavalli, M Remke, L Rampasek, J Peacock, Djh Shih, B Luu, L Garzia, J Torchia, C Nör, A S Morrissy, S Agnihotri, Y Y Thompson, C M Kuzan-Fischer, H Farooq, K Isaev, C Daniels, B K Cho, S K Kim, K C Wang, J Y Lee, W A Grajkow... |
3,421,066 | HDAC and MAPK/ERK Inhibitors Cooperate To Reduce Viability and Stemness in MedulloblastomaRampasek L, Peacock J, Shih DJH, Luu B, Garzia L, Torchia J, Nör C, Morrissy AS, Agnihotri S, Thompson YY, Kuzan-Fischer CM, Farooq H, Isaev K, Daniels C, Cho BK, Kim SK, Wang KC, Lee JY, Grajkowska WA, Perek-Polnik M, Vasiljevic ... |
3,421,067 | HDAC and MAPK/ERK Inhibitors Cooperate To Reduce Viability and Stemness in MedulloblastomaInhibition of phosphorylated STAT3 by cucurbitacin I enhances chemoradiosensitivity in medulloblastoma-derived cancer stem cells. C J Chang, C H Chiang, W S Song, S K Tsai, L C Woung, C H Chang, S Y Jeng, C Y Tsai, C C Hsu, H F Le... |
3,421,068 | HDAC and MAPK/ERK Inhibitors Cooperate To Reduce Viability and Stemness in MedulloblastomaEpigenetic states of cells of origin and tumor evolution drive tumor-initiating cell phenotype and tumor heterogeneity. K H Chow, D M Shin, M H Jenkins, E E Miller, D J Shih, S Choi, B E Low, V Philip, B Rybinski, R T Bronson, M D... |
3,421,069 | HDAC and MAPK/ERK Inhibitors Cooperate To Reduce Viability and Stemness in MedulloblastomaTargeting class I histone deacetylase 2 in MYC amplified group 3 medulloblastoma. J Ecker, I Oehme, R Mazitschek, A Korshunov, M Kool, T Hielscher, J Kiss, F Selt, C Konrad, M Lodrini, H E Deubzer, A Von Deimling, A E Kulozik, S M... |
3,421,070 | HDAC and MAPK/ERK Inhibitors Cooperate To Reduce Viability and Stemness in MedulloblastomaMicroarray analysis identifies a death-from-cancer signature predicting therapy failure in patients with multiple types of cancer. G V Glinsky, O Berezovska, A B Glinskii, J Clin Invest. 115Glinsky GV, Berezovska O, Glinskii AB (2... |
3,421,071 | HDAC and MAPK/ERK Inhibitors Cooperate To Reduce Viability and Stemness in MedulloblastomaCancerous stem cells can arise from pediatric brain tumors. H D Hemmati, I Nakano, J A Lazareff, M Masterman-Smith, D H Geschwind, M Bronner-Fraser, H I Kornblum, Proc Natl Acad Sci U S A. 100Hemmati HD, Nakano I, Lazareff JA, Mas... |
3,421,072 | HDAC and MAPK/ERK Inhibitors Cooperate To Reduce Viability and Stemness in MedulloblastomaEngineering genetic predisposition in human neuroepithelial stem cells recapitulates medulloblastoma tumorigenesis. M Huang, J Tailor, Q Zhen, A H Gillmor, M L Miller, H Weishaupt, J Chen, T Zheng, E K Nash, L K Mchenry, Z An, F Y... |
3,421,073 | HDAC and MAPK/ERK Inhibitors Cooperate To Reduce Viability and Stemness in MedulloblastomaThe landscape of somatic mutations in epigenetic regulators across 1,000 paediatric cancer genomes. R Huether, L Dong, X Chen, G Wu, M Parker, L Wei, J Ma, M N Edmonson, E K Hedlund, M C Rusch, S A Shurtleff, H L Mulder, K Boggs, ... |
3,421,074 | HDAC and MAPK/ERK Inhibitors Cooperate To Reduce Viability and Stemness in MedulloblastomaIn vitro models of medulloblastoma: choosing the right tool for the job. D P Ivanov, B Coyle, D A Walker, A M Grabowska, J Biotechnol. 236Ivanov DP, Coyle B, Walker DA, Grabowska AM (2016) In vitro models of medulloblastoma: choos... |
3,421,075 | HDAC and MAPK/ERK Inhibitors Cooperate To Reduce Viability and Stemness in MedulloblastomaPhenylbutyrate and phenylacetate induce differentiation and inhibit proliferation of human medulloblastoma cells. X N Li, S Parikh, Q Shu, H L Jung, C W Chow, L Perlaky, H C Leung, J Su, S Blaney, C C Lau, Clin Cancer Res. 10Li XN... |
3,421,076 | HDAC and MAPK/ERK Inhibitors Cooperate To Reduce Viability and Stemness in MedulloblastomaEvaluation of radiotherapy effect in resveratrol-treated medulloblastoma cancer stemlike cells. K H Lu, Y W Chen, P H Tsai, M L Tsai, Y Y Lee, C Y Chiang, C L Kao, S H Chiou, H H Ku, C H Lin, Y J Chen, Childs Nerv Syst. 25Lu KH, C... |
3,421,077 | HDAC and MAPK/ERK Inhibitors Cooperate To Reduce Viability and Stemness in MedulloblastomaFoxG1 interacts with Bmi1 to regulate selfrenewal and tumorigenicity of medulloblastoma stem cells. B Manoranjan, X Wang, R M Hallett, C Venugopal, S C Mack, N Mcfarlane, S M Nolte, K Scheinemann, T Gunnarsson, J A Hassell, M D Ta... |
3,421,078 | HDAC and MAPK/ERK Inhibitors Cooperate To Reduce Viability and Stemness in Medulloblastoma. P A Northcott, G W Robinson, C P Kratz, D J Mabbott, S L Pomeroy, S C Clifford, S Rutkowski, D W Ellison, D Malkin, M D Taylor, A Gajjar, S M Pfister, Nat Rev Dis Primers. 511Northcott PA, Robinson GW, Kratz CP, Mabbott DJ, Pome... |
3,421,079 | HDAC and MAPK/ERK Inhibitors Cooperate To Reduce Viability and Stemness in MedulloblastomaA large-scale drug screen identifies selective inhibitors of class I HDACs as a potential therapeutic option for SHH medulloblastoma. E Pak, E L Mackenzie, X Zhao, M F Pazyra-Murphy, Pmc Park, L Wu, D L Shaw, E C Addleson, S S Cay... |
3,421,080 | HDAC and MAPK/ERK Inhibitors Cooperate To Reduce Viability and Stemness in MedulloblastomaPanobinostat, a histone deacetylase inhibitor, suppresses leptomeningeal seeding in a medulloblastoma animal model. J H Phi, S A Choi, P A Kwak, J Y Lee, K C Wang, D W Hwang, S K Kim, Oncotarget. 8Phi JH, Choi SA, Kwak PA, Lee JY,... |
3,421,081 | HDAC and MAPK/ERK Inhibitors Cooperate To Reduce Viability and Stemness in MedulloblastomaNovel mutations target distinct subgroups of medulloblastoma. G Robinson, M Parker, T A Kranenburg, C Lu, X Chen, L Ding, T N Phoenix, E Hedlund, L Wei, X Zhu, N Chalhoub, S J Baker, R Huether, R Kriwacki, N Curley, R Thiruvenkata... |
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