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Title: Direct involvement of macrophages in destruction of beta-cells leading to development of diabetes in virus-infected mice. Abstract: A single administration of complete Freund's adjuvant (CFA), type 1 carrageenan (Car), or silica 7, 2, and 2 days, respectively, before infection with a low dose (1 x 10(2) plaque-f...
0
2
pubmed
train
0
Title: Accelerated diabetes in non-obese diabetic (NOD) mice differing in incidence of spontaneous disease. Abstract: The NOD mouse is an established model of autoimmune diabetes mellitus. Various lines of NOD mice differ in their incidence of spontaneous diabetes, e.g. 93% of female NOD/Lt mice compared with 46% of fe...
0
2
pubmed
train
1
Title: Prevalence and risk factors for urinary incontinence in women with type 2 diabetes and impaired fasting glucose: findings from the National Health and Nutrition Examination Survey (NHANES) 2001-2002. Abstract: OBJECTIVE: Diabetes is associated with increased risk of urinary incontinence. It is unknown whether wo...
2
1
pubmed
train
2
Title: Addition of pramlintide to insulin therapy lowers HbA1c in conjunction with weight loss in patients with type 2 diabetes approaching glycaemic targets. Abstract: AIM: Two long-term, randomized, double-blind, placebo-controlled clinical trials in insulin-using patients with type 2 diabetes, spanning a wide range ...
2
2
pubmed
train
3
Title: HLA and insulin gene associations with IDDM. Abstract: The HLA DR genotype frequencies in insulin-dependent diabetes mellitus (IDDM) patients and the frequencies of DR alleles transmitted from affected parent to affected child both indicate that the DR3-associated predisposition is more "recessive" and the DR4-a...
1
2
pubmed
train
4
Title: Administering glutamic acid decarboxylase to NOD mice prevents diabetes. Abstract: Type 1 diabetes is the result of an ongoing autoimmune response to specific proteins expressed by the insulin producing beta cells. Recently, a number of beta cell autoantigens have been identified. However, their role in mediatin...
1
2
pubmed
train
5
Title: Accelerated diabetes in non-obese diabetic (NOD) mice differing in incidence of spontaneous disease. Abstract: The NOD mouse is an established model of autoimmune diabetes mellitus. Various lines of NOD mice differ in their incidence of spontaneous diabetes, e.g. 93% of female NOD/Lt mice compared with 46% of fe...
0
1
pubmed
train
6
Title: Inflammation is more persistent in type 1 diabetic mice. Abstract: Whether diabetes enhances or diminishes the host response to bacteria has been controversial. To determine how diabetes alters the inflammatory response, we inoculated P. gingivalis into the scalps of mice rendered diabetic with multiple low-dose...
0
2
pubmed
train
7
Title: IL-1alpha, IL-1beta, and IFN-gamma mark beta cells for Fas-dependent destruction by diabetogenic CD4(+) T lymphocytes. Abstract: Cytokines such as IL-1alpha, IL-1beta, and IFN-gamma have long been implicated in the pathogenesis of autoimmune diabetes, but the mechanisms through which they promote diabetogenesis ...
1
1
pubmed
train
8
Title: Onset of diabetes in Zucker diabetic fatty (ZDF) rats leads to improved recovery of function after ischemia in the isolated perfused heart. Abstract: The aim of this study was to determine whether the transition from insulin resistance to hyperglycemia in a model of type 2 diabetes leads to intrinsic changes in ...
2
2
pubmed
train
9
Title: Prevalence and risk factors for urinary incontinence in women with type 2 diabetes and impaired fasting glucose: findings from the National Health and Nutrition Examination Survey (NHANES) 2001-2002. Abstract: OBJECTIVE: Diabetes is associated with increased risk of urinary incontinence. It is unknown whether wo...
2
2
pubmed
train
10
Title: Comparative trial between insulin glargine and NPH insulin in children and adolescents with type 1 diabetes mellitus. Abstract: The objective of this study was to compare the efficacy and safety of insulin glargine, a long-acting insulin analog, with NPH insulin in children and adolescents with type 1 diabetes m...
1
2
pubmed
train
11
Title: Administering glutamic acid decarboxylase to NOD mice prevents diabetes. Abstract: Type 1 diabetes is the result of an ongoing autoimmune response to specific proteins expressed by the insulin producing beta cells. Recently, a number of beta cell autoantigens have been identified. However, their role in mediatin...
1
1
pubmed
train
12
Title: Genetic requirements for acceleration of diabetes in non-obese diabetic mice expressing interleukin-2 in islet beta-cells. Abstract: Diabetes was dramatically accelerated in non-obese diabetic (NOD) transgenic mice that expressed interleukin-2 (IL-2) in their beta cells. A single cross to C57BL/6 completely prev...
1
1
pubmed
train
13
Title: Mutations in the small heterodimer partner gene are associated with mild obesity in Japanese subjects. Abstract: Mutations in several genes encoding transcription factors of the hepatocyte nuclear factor (HNF) cascade are associated with maturity-onset diabetes of the young (MODY), a monogenic form of early-onse...
2
1
pubmed
train
14
Title: Comparative trial between insulin glargine and NPH insulin in children and adolescents with type 1 diabetes mellitus. Abstract: The objective of this study was to compare the efficacy and safety of insulin glargine, a long-acting insulin analog, with NPH insulin in children and adolescents with type 1 diabetes m...
1
1
pubmed
train
15
Title: Prevalence and risk factors for urinary incontinence in women with type 2 diabetes and impaired fasting glucose: findings from the National Health and Nutrition Examination Survey (NHANES) 2001-2002. Abstract: OBJECTIVE: Diabetes is associated with increased risk of urinary incontinence. It is unknown whether wo...
2
2
pubmed
train
16
Title: IL-1alpha, IL-1beta, and IFN-gamma mark beta cells for Fas-dependent destruction by diabetogenic CD4(+) T lymphocytes. Abstract: Cytokines such as IL-1alpha, IL-1beta, and IFN-gamma have long been implicated in the pathogenesis of autoimmune diabetes, but the mechanisms through which they promote diabetogenesis ...
1
2
pubmed
train
17
Title: How, when, and why to predict IDDM. Abstract: Insulin-dependent diabetes remains a serious disease replete with life-threatening complications. The onset of the disease is becoming increasingly predictable through the detection of its associated autoantibodies. The natural history of pathogenic events is attenua...
1
2
pubmed
train
18
Title: Relationships between angiotensin I converting enzyme gene polymorphism, plasma levels, and diabetic retinal and renal complications. Abstract: Insulin-dependent diabetes mellitus (IDDM), cardiovascular morbidity, and vital prognosis are linked to diabetic nephropathy, which is probably determined by renal hemod...
1
2
pubmed
train
19
Title: IL-1alpha, IL-1beta, and IFN-gamma mark beta cells for Fas-dependent destruction by diabetogenic CD4(+) T lymphocytes. Abstract: Cytokines such as IL-1alpha, IL-1beta, and IFN-gamma have long been implicated in the pathogenesis of autoimmune diabetes, but the mechanisms through which they promote diabetogenesis ...
1
1
pubmed
train
20
Title: Prevalence and risk factors for urinary incontinence in women with type 2 diabetes and impaired fasting glucose: findings from the National Health and Nutrition Examination Survey (NHANES) 2001-2002. Abstract: OBJECTIVE: Diabetes is associated with increased risk of urinary incontinence. It is unknown whether wo...
2
2
pubmed
train
21
Title: HLA and insulin gene associations with IDDM. Abstract: The HLA DR genotype frequencies in insulin-dependent diabetes mellitus (IDDM) patients and the frequencies of DR alleles transmitted from affected parent to affected child both indicate that the DR3-associated predisposition is more "recessive" and the DR4-a...
1
2
pubmed
train
22
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