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The Weighted Pooled Prevalence (WPP) of COVID-19 associated abdominal pain is approximately 6.2% (2.6%-10.3%). The information is based upon the systematic review and meta-analysis including 78 observational studies (from Dec 2019 to May 7th, 2020). The p... | What is the connection between COVID-19 and the experience of abdominal pain? |
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It has been estimated that 20-25% of patients with COVID-19 had diabetes. Based on a Meta-analysis, the prevalence of diabetes among Chinese population with COVID-19 was 9·7%. A study done on 1317 participants reported that 88.5% of patients with COVID-1... | How has COVID-19 affected people with diabetes? |
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Clinical characteristics of 1544 Brazilians aged 60 years and over with laboratory evidence for SARS-CoV-2
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| INTRODUCTION: Infection with the new coronavirus responsible for Severe Acute Respiratory Syndrome (SARS-CoV-2) continues to spread worldwide. In Brazil, there are already more than 230 thousand dead, many of these older adults. OBJECTIVE: To present the clinical characteristics of older Brazilian adults infected by CO... |
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Clinical and virological course of SARS-CoV 2 infected patients in a tertiary care hospital in Pakistan
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| Background: Acute respiratory illness caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) involved the whole globe within no time Various studies published globally have shown variable severity of disease and mortality The objective of our study was to describe clinical and epidemiological characteri... |
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Management of tracheostomy in COVID-19 patients: The Japanese experience
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| OBJECTIVE: Involvement in the tracheostomy procedure for COVID-19 patients can lead to a feeling of fear in medical staff. To address concerns over infection, we gathered and analyzed experiences with tracheostomy in the COVID-19 patient population from all over Japan. METHODS: The data for health-care workers involved... |
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Oral Health Conditions and COVID-19: A Systematic Review and Meta-analysis of the Current Evidence
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| BACKGROUND: : The coronavirus disease 2019 (COVID-19) pandemic has highlighted the importance of understanding the underlying conditions that lead to COVID-19. Oral health has systemic implications in the maintenance of a healthy state. This study aimed to summarize evidence on the prevalence of oral health conditions ... |
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The Risk Factors and Clinical Outcomes Associated with Acute Kidney Injury in Patients with COVID-19: Data from a Large Cohort in Iran
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| INTRODUCTION: Kidney involvement, ranging from mild hematuria and proteinuria to acute kidney injury (AKI) in patients with coronavirus disease-2019 (COVID-19), is a recent finding with various incidence rates reported among hospitalized patients with COVID-19. Given the various AKI rates and their associated risk fact... |
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Early predictors and screening tool developing for severe patients with COVID-19
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| Background: Coronavirus disease 2019 (COVID-19) is a declared global pandemic, causing a lot of death. How to quickly screen risk population for severe patients is essential for decreasing the mortality. Methods: This retrospective study included all the 813 confirmed cases diagnosed with COVID-19 before March 2 nd , 2... |
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Dying in times of the coronavirus: An online survey among healthcare professionals about end-of-life care for patients dying with and without COVID-19 (the CO-LIVE study)
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| BACKGROUND: During the COVID-19 outbreak restricting measures may have affected the provision of good end-of-life care for patients with and without COVID-19. AIM: To describe characteristics of patients who died and the care they received, and to examine how patient characteristics, setting and visiting restrictions a... |
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COVID–19の第1波への対応に係るJAAM全国調査(JAAM Nationwide Survey on the response to the first wave of COVID–19 in Japan): ～第1部：医療機関はどのように診療体制を整えたか～(– Part I: How to set up a treatment system in each hospital –)
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| Aim: To clarify how the medical institutions overcame the first wave of coronavirus disease 2019 (COVID–19) in Japan and to discuss its impact on the medical labor force. Methods: We analyzed questionnaire data from the end of May 2020 from 180 hospitals (102,578 beds) certified by the Japanese Association for Acute Me... |
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Olfactory Dysfunction in Coronavirus Disease 2019 Patients: Observational Cohort Study and Systematic Review
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| Background: Olfactory dysfunction (OD) has been reported in coronavirus disease 2019 (COVID-19). However, there are knowledge gaps about the severity, prevalence, etiology, and duration of OD in COVID-19 patients. Methods: Olfactory function was assessed in all participants using questionnaires and the butanol threshol... |
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Point prevalence survey to evaluate the seropositivity for coronavirus disease 2019 (COVID-19) among high-risk healthcare workers
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| Among 1,770 healthcare workers serving in high-risk care areas for coronavirus disease 2019 (COVID-19), 39 (2.2%) were seropositive. Exposure to severe acute respiratory coronavirus virus 2 (SARS-CoV-2) in the community was associated with being seropositive. Job or unit type and percentage of time working with COVID-1... |
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Pulmonary fibrosis and its related factors in discharged patients with new coronavirus pneumonia: A cohort study
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| Background: Thousands of the Coronavirus Disease 2019 (COVID-19) patients have been discharged from hospitals, persistent follow-up studies are required to evaluate the prevalence of post-COVID-19 fibrosis. Methods: : This study involves 462 laboratory confirmed patients with COVID-19 who were admitted to Shenzhen Thir... |
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Disparities in case frequency and mortality of coronavirus disease 2019 (COVID-19) among various states in the United States
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| OBJECTIVE: To utilize publicly reported, state-level data to identify factors associated with the frequency of cases, tests, and mortality in the USA. MATERIALS AND METHODS: Retrospective study using publicly reported data collected included the number of COVID-19 cases, tests and mortality from March 14th through Apri... |
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Arrhythmias in patients with coronavirus disease 2019 (COVID-19) in Wuhan, China: Incidences and implications
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| BACKGROUND: Coronavirus disease 2019 (COVID-19) continues to impact populations around the globe. Information regarding the incidences and implications of arrhythmias in COVID-19 is limited. METHODS: A total of 463 patients with COVID-19 and who had at least one electrocardiogram recording from February 1 to March 19, ... |
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Coronavirus Disease 2019 and Kidney Transplantation in Saudi Arabia: Outcomes and Future Opportunities
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| BACKGROUND: Kidney transplant services all over the world were severely impacted by the coronavirus disease 2019 pandemic. The optimum management of kidney transplant recipients with coronavirus disease 2019 remains uncertain. MATERIAL/METHODS: We conducted a multicenter cohort study of kidney transplant recipients wit... |
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Demographic & clinical profile of patients with COVID-19 at a tertiary care hospital in north India.
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| Background & objectives The COVID-19 pandemic emerged as a major public health emergency affecting the healthcare services all over the world. It is essential to analyze the epidemiological and clinical characteristics of patients with COVID-19 in different parts of our country. This study highlights clinical experienc... |
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COVID‐19 in lung transplant recipients: A single‐center experience
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| BACKGROUND: Coronavirus disease 2019 (COVID‐19) is a global health problem. However, the course of this disease in immunosuppressed patients remains unknown. This study aimed to describe the course of COVID‐19 infection and its effects on lung transplant recipients. METHODS: This was a single‐center, retrospective, obs... |
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Six-month smell and taste recovery rates in coronavirus disease 2019 patients: a prospective psychophysical study
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| BACKGROUND: The long-term recovery rate for coronavirus disease 2019 related chemosensory disturbances has not yet been clarified. METHODS: Olfactory and gustatory functions were assessed with psychophysical tests in patients in the first seven days from coronavirus disease 2019 onset and one, two, three and six months... |
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Mortality Among Noncoronavirus Disease 2019 Critically Ill Patients Attributable to the Pandemic in France
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| OBJECTIVES: We investigated whether the risk of death among noncoronavirus disease 2019 critically ill patients increased when numerous coronavirus disease 2019 cases were admitted concomitantly to the same hospital units. DESIGN: We performed a nationwide observational study based on the medical information system fro... |
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[Analysis of the changes of inflammatory cytokine levels in patients with critical coronavirus disease 2019 undergoing invasive mechanical ventilation].
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| OBJECTIVE To investigate the relationship between the changes of inflammatory cytokine levels and prognosis of patients with critical coronavirus disease 2019 (COVID-19) undergoing invasive mechanical ventilation (IMV). METHODS A retrospective study was conducted. The clinical date of critical COVID-19 patients undergo... |
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Impact of COVID-19 on serum melatonin levels and sleep parameters in children
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| BACKGROUND/AIM: This study aimed to analyze the serum melatonin levels and changes in sleep patterns in pediatric patients with coronavirus disease 2019 (COVID-19). MATERIALS AND METHODS: This study was designed as a descriptive, cross-sectional study. Serum melatonin levels and sleep parameters of children with the di... |
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Six Months Follow-Up of Patients with Invasive Mechanical Ventilation due to COVID-19 Related ARDS
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| Although patients who recovered from acute coronavirus disease 2019 (COVID-19) may have prolonged disabilities, follow-up data of those who have survived COVID-19 related acute respiratory distress syndrome (ARDS) is still very scarce. Therefore, COVID-19-ARDS survivors requiring invasive mechanical ventilation (IMV) w... |
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[Retrospective analysis of nosocomial COVID-19: a comparison between patients with hematological disorders and other diseases]
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| Nosocomial coronavirus disease 2019 (COVID-19) had occurred at our hospital We retrospectively analyzed the differences between patients with nosocomial COVID-19 and either hematological disease (n=40) or other diseases (n=57) The analysis was completed within 60 days for surviving patients Among the patients with hema... |
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AGA Institute Rapid Review of the Gastrointestinal and Liver Manifestations of COVID-19, Meta-Analysis of International Data, and Recommendations for the Consultative Management of Patients with COVID-19
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| BACKGROUND & AIMS: Multiple gastrointestinal (GI) symptoms, including diarrhea, nausea/vomiting, and abdominal pain, as well as liver enzyme abnormalities, have been variably reported in patients with coronavirus disease 2019 (COVID-19). This document provides best practice statements and recommendations for consultati... |
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Comparison of Comorbidities in Relation to Critical Conditions among Coronavirus Disease 2019 Patients: A Network Meta-Analysis
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| Severe illness and poor outcome are mainly associated with aging or certain medical comorbidities, especially chronic diseases. However, factors for unfavorable prognosis have not been well described owing to relatively small sample sizes and single-center reports. Therefore, this study aimed to compare the contributio... |
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Clinical course and outcomes of COVID-19 in rheumatic disease patients: a case cohort study with a diverse population
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| OBJECTIVE: To determine clinical course and outcomes in rheumatic disease patients with coronavirus disease 2019 (COVID-19) and compare results to uninfected patients. METHODS: We conducted a case cohort study of autoimmune disease patients with COVID-19 (confirmed by severe acute respiratory syndrome coronavirus 2 PCR... |
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The Impact of Coronavirus Disease 2019 (COVID-19) on Retinal Microcirculation in Human Subjects.
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| BACKGROUND The aim of the study was to assess retinal microcirculation in patients with coronavirus disease 2019 (COVID-19) through the use of optical coherence tomography angiography (OCT-A) and compare the results with those obtained in healthy controls. METHODS The study enrolled 39 patients who had fully recovered ... |
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Manifestations of COVID-19 in pregnant women with focus on gastrointestinal symptoms: a systematic review
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| Aim: This review study was conducted to evaluate the symptoms of COVID-19 in pregnant women with a focus on gastrointestinal symptoms. Background: COVID-19 is a fatal respiratory disease caused by a novel coronavirus that quickly became a pandemic. Although the main symptoms of this disease include respiratory symptoms... |
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Clinical Characteristics, Serological and Radiological Longitudinal Changes of Patients with COVID-19.
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| BACKGROUND Since December 2019, an outbreak of coronavirus disease 2019 (COVID-19) began in Wuhan and rapidly spread globally. The speed and scope of the spread of COVID-19 makes it urgent to define clinical characteristics, serological and radiological changes of the affected patients. METHODS Seven patients with labo... |
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Clinical course and outcomes of COVID-19 patients with hypertension
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| Background: Coronavirus disease 2019 (COVID-19) is now still an emerging, evolving pandemic, causing more than 64 million people infected. Hypertension, a common cardiovascular condition, has been reported as a risk factor for higher mortality. In order to a better management, it is necessary to know the clinical cours... |
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Characterization and Outcomes of Hospitalized Children With Coronavirus Disease 2019: A Report From a Multicenter, Viral Infection and Respiratory Illness Universal Study (Coronavirus Disease 2019) Registry
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| OBJECTIVES: Multicenter data on the characteristics and outcomes of children hospitalized with coronavirus disease 2019 are limited. Our objective was to describe the characteristics, ICU admissions, and outcomes among children hospitalized with coronavirus disease 2019 using Society of Critical Care Medicine Discovery... |
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Clinical-epidemiological and treatment characteristics of children with COVID-19 in a tertiary referral center in Peru
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| Introduction The COVID-19 pandemic has a great impact on children's health. This study describes the clinical, epidemiological and treatment characteristics of children presenting COVID-19 at the Instituto Nacional de Salud del Nino San Borja (INSN-SB) Methods This was a retrospective study of patients with a confirmed... |
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Factors associated with delayed viral shedding in COVID-19 infected patients: A retrospective small-scale study
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| BACKGROUND: The outbreak of COVID-19 has caused ever-increasing attention and public panic all over the world. Until now, data are limited about the risk factors to virus shedding in COVID-19 infected patients. METHODS: In this retrospective study, data were collected from 87 patients hospitalized with COVID-19 infecti... |
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Acute respiratory distress syndrome (ARDS) and inflammatory bowel disease (IBD): A nationwide retrospective study
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| INTRODUCTION: With the recent Coronavirus Disease-19 (COVID-19) pandemics, intensive care units (ICUs) across the country have been overrun with patients in florid acute respiratory distress syndrome (ARDS) Inflammatory bowel disease (IBD) as its name suggests is a pathologic condition that results in an exaggerated in... |
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Profile of kidney disease patients in covid-19 isolation wards denpasar-baliindonesia
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| Introduction: COVID-19 is a new, highly infectious, and life-threatening disease and can aggravate the previous kidney disease Objectives: This study aims to describe the prevalence and profile of acute kidney injury (AKI), Acute on Chronic Kidney Disease (ACKD) and CKD in our COVID-19 patients isolation wards Methodol... |
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Saliva viral load better correlates with clinical and immunological profiles in children with coronavirus disease 2019
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| BACKGROUND: Pediatric COVID-19 studies exploring the relationships between NPS and saliva viral loads, clinical and immunological profiles are lacking. METHODS: Demographics, immunological profiles, nasopharyngeal swab (NPS), and saliva samples collected on admission, and hospital length of stay (LOS) were assessed in ... |
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Recurrence of COVID-19 Documented with RT-PCR.
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| We present a case of coronavirus disease 2019 (COVİD-19) re-infection where the time interval between two COVİD-positive episodes is the longest in the literature. A 40-year male patient was admitted to the Emergency Department with complaints of sore throat, cough and diarrhea; and was re-diagnosed as COVİD-19 positiv... |
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Prediction on the Number of Confirmed Covid-19 With the FUDAN-CCDC Mathematical Model and Its Epidemiology, Clinical Manifestations, And Prevention and Treatment Effects
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| this study was to explore the development trend and clinical manifestations of COVID-19 better. The number of confirmed novel coronavirus pneumonia (COVID-19) was predicted based on the FUDAN-CCDC mathematical model (which was a new model namely based on the novel time delay dynamic model and the statistical data from ... |
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[Three cases of COVID-19 in elderly patients with delayed release from isolation due to persistent positive polymerase chain reaction findings].
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| The coronavirus disease 2019 (COVID-19) infection has spread worldwide, with no sign of its control in Japan yet. Eight elderly COVID-19 patients over 90 years of age were treated at our hospital. We herein report three cases with characteristic progression. Case 1 was a 91-year-old female patient diagnosed with bacter... |
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Obesity as an Important Marker of the COVID-19 Pandemic
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| Introduction: In December 2019, the emergence of the new coronavirus disease 2019 (COVID-19) began in Wuhan, China. Thereafter, the disease has been spreading rapidly across the world, with about 300 million registered cases worldwide, and the numbers are also exponentially increasing in India, with about 34 million re... |
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Factors Associated with the Exacerbation of COVID-19 Disease: A Case-control Study
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| AIMS AND OBJECTIVES: To investigate the factors associated with the exacerbations of COVID-19 BACKGROUND: At present, COVID-19 is prevalent in the world, seriously endangering the property and life safety of people around the world Currently, there are many reports on the clinical features, complications and risk facto... |
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Impact of coronavirus disease 2019 on infectious disease treatment and infection control at a tertiary hospital in Japan
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| INTRODUCTION: Coronavirus disease 2019 (COVID-19) has greatly impacted medical care practices. Although the effects on infectious disease treatment and infection control, such as antimicrobial resistance, have been specified, very few reports exist on the specific effects of COVID-19. METHODS: We investigated the effec... |
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840. Clinical Characteristics of Patients Living with HIV Hospitalized for COVID-19
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| BACKGROUND: Limited data exists regarding the impact of coronavirus disease 2019 (COVID-19) on people living with human immunodeficiency virus (PLWH). The purpose of the study was to compare the clinical outcomes of patients hospitalized with COVID-19 and HIV versus those without HIV. METHODS: This was a retrospective,... |
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High rate of bleeding and arterial thrombosis in COVID-19: Saudi multicenter study
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| BACKGROUND: Several observational studies have reported the rate of venous and arterial thrombotic events in patients infected with COVID-19, with conflicting results. The aim of this study was to estimate the rate of thrombotic and bleeding events in hospitalized patients diagnosed with Coronavirus disease 2019 (COVID... |
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Spontaneous Pneumothorax: An Emerging Complication of COVID-19 Pneumonia
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| Spontaneous Pneumothorax in the setting of coronavirus disease 19 (COVID-19) has been rarely described and is a potentially lethal complication. We report our institutional experience. Patients with confirmed COVID-19 who were admitted at 5 hospitals within the Inova health system between February 21 and May 2020 were ... |
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Attributes and predictors of long COVID
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| Reports of long-lasting coronavirus disease 2019 (COVID-19) symptoms, the so-called 'long COVID', are rising but little is known about prevalence, risk factors or whether it is possible to predict a protracted course early in the disease. We analyzed data from 4,182 incident cases of COVID-19 in which individuals self-... |
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Clinical outcome of renin-angiotensin-aldosterone system blockers in treatment of hypertensive patients with COVID-19: a systematic review and meta-analysis
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| BACKGROUND: Novel coronavirus disease 2019 has been stated as global disease pandemic due to its rapid spread worldwide. Up to 30% of coronavirus disease 2019 patients with hypertension are more susceptible to death. Angiotensin-converting enzyme inhibitors and angiotensin receptor blockers have been used as primary li... |
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Postdischarge rheumatic and musculoskeletal symptoms following hospitalization for COVID-19: prospective follow-up by phone interviews
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| To describe the rheumatic and musculoskeletal symptoms at hospitalization as well as their persistence/severity after discharge with coronavirus disease 2019 (COVID-19) and to identify whether age, sex, body mass index (BMI), and length of hospital stay are associated with persistence of these symptoms. In this single-... |
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The Association of "Loss of Smell" to COVID-19: A Systematic Review and Meta-Analysis
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| BACKGROUND: The presence of olfactory dysfunction or "loss of smell" has been reported as an atypical symptom in patients with coronavirus disease 2019 (COVID-19). We performed a systematic review and meta-analysis of the available literature to evaluate the prevalence of "loss of smell" in COVID-19 as well as its util... |
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Comparison of Clinical Characteristics and Outcome of Critically Ill Patients Admitted to Tertiary Care Intensive Care Units in India during the Peak Months of First and Second Waves of COVID-19 Pandemic: A Retrospective Analysis
### Respons... | BACKGROUND: Coronavirus disease-2019 (COVID-19) continues to pose serious challenges to healthcare systems globally with the disease progressing over time in crest-trough pattern of waves. We compared the patient characteristics and outcomes of critically ill patients admitted during the first and second waves of COVID... |
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Prevalence of Underlying Medical Conditions Associated With Severe COVID-19 Illness in Adult Cancer Survivors in the United States
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| Cancer, and other underlying medical conditions including chronic obstructive pulmonary disease, heart diseases, diabetes, chronic kidney disease, and obesity, are associated with increased risk of severe coronavirus disease 2019 (COVID-19) illness. We identified 6411 cancer survivors and 77 748 adults without a cancer... |
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Is positivity for hepatitis C virus antibody predictive of lower risk of death in COVID-19 patients with cirrhosis?
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| Liver injury has been reported in coronavirus disease 2019 (COVID-19) cases but the impact of pre-existing liver damage and related etiology have not been completely elucidated Our research interests include the potential reciprocal influence of COVID-19 and pre-existing liver damage related to hepatitis C virus (HCV) ... |
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Epidemiological and clinical characteristics of 136 cases of COVID-19 in main district of Chongqing
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| Background We did a comprehensive exploration of the epidemiological and clinical characteristics of 136 patients with confirmed COVID-19 in main district of Chongqing which was adjacent to the west of Hubei province. Methods This study was conducted on 136 patients with COVID-19 in main district of Chongqing from Jan ... |
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Coronavirus Disease 2019 ICU Patients Have Higher-Than-Expected Acute Physiology and Chronic Health Evaluation-Adjusted Mortality and Length of Stay Than Viral Pneumonia ICU Patients
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| OBJECTIVES: To compare Acute Physiology and Chronic Health Evaluation-IV-adjusted mortality and length of stay outcomes of adult ICU patients who tested positive for coronavirus disease 2019 with patients admitted to ICU with other viral pneumonias including a subgroup with viral pneumonia and concurrent acute respirat... |
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Association Between Statin Use Prior to Admission and Lower Coronavirus Disease 2019 (COVID-19) Severity in Patients With Cardiovascular Disease or Risk Factors.
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| BACKGROUND Cardiovascular diseases and/or risk factors (CVDRF) have been reported as risk factors for severe coronavirus disease 2019 (COVID-19).Methods and Results:In total, we selected 693 patients with CVDRF from the CLAVIS-COVID database of 1,518 cases in Japan. The mean age was 68 years (35% females). Statin use w... |
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Sex-Related Differences in Clinical Presentation and Risk Factors for Mortality in Patients Hospitalized With Coronavirus Disease 2019 in New York City
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| We evaluated sex-related differences in symptoms and risk factors for mortality in 4798 patients hospitalized with coronavirus disease 2019 in New York City. When adjusted for age and comorbidities, being male was an independent predictor of death with mortality significantly higher than females, even with low severe a... |
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Clinical Manifestations and Outcomes of Critically Ill Children and Adolescents with Coronavirus Disease 2019 in New York City
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| OBJECTIVES: To describe the clinical manifestations and outcomes of critically ill children with coronavirus disease-19 (COVID-19) in New York City. STUDY DESIGN: Retrospective observational study of children 1 month to 21 years admitted March 14 to May 2, 2020, to 9 New York City pediatric intensive care units (PICUs)... |
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COVID‐19 and immunological dysregulation: can autoantibodies be useful?
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| Coronavirus disease 2019 (COVID‐19) is often associated with interstitial pneumonia. However, there is insufficient knowledge on the presence of autoimmune serological markers in patients with COVID‐19. We analyzed the presence and role of autoantibodies in patients with COVID‐19‐associated pneumonia. We prospectively ... |
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Comparison of hematological parameters and perinatal outcomes between COVID-19 pregnancies and healthy pregnancy cohort.
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| OBJECTIVES To evaluate the relationship between Coronavirus Disease 2019 (COVID-19) in pregnancy and adverse perinatal outcomes. The secondary aim is to analyze the diagnostic value of hematologic parameters in COVID-19 complicated pregnancies. METHODS The current study is conducted in a high volume tertiary obstetrics... |
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Risk factors associated with morbidity and mortality outcomes of COVID-19 patients on the 28th day of the disease course: a retrospective cohort study in Bangladesh
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| Diverse risk factors intercede the outcomes of coronavirus disease 2019 (COVID-19). We conducted this retrospective cohort study with a cohort of 1016 COVID-19 patients diagnosed in May 2020 to identify the risk factors associated with morbidity and mortality outcomes. Data were collected by telephone-interview and rev... |
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Symptom Course in COVID-19 Outpatients
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| Objective: Describe the disease course in a cohort of outpatients with covid-19 and evaluate factors predicting duration of symptoms Design: Retrospective cohort study Setting: Telemedicine clinic at a large medical system in Atlanta, Georgia Participants: 273 patients with COVID-19. Exclusion criteria included: (1) in... |
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Long-term clinical and biochemical residue after COVID-19 recovery
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| BACKGROUND: The long-term health consequences of coronavirus disease 2019 (COVID-19) are still unclear. The majority of previous trials addressed the post-COVID-19 symptoms through comprehensive medical questionnaires for relatively short periods after recovery. We tried to detect the potential pathological clinical si... |
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Barotrauma in mechanically-ventilated patients with coronavirus disease 2019: a survey of 38 hospitals in Lombardy, Italy.
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| BACKGROUND The aim was to describe the incidence and risk factors of barotrauma in patients with the coronavirus disease 2019 (COVID-19) on invasive mechanical ventilation, during the outbreak in our region (Lombardy, Italy). METHODS The study was an electronic survey open from March 27th to May 2nd, 2020. Patients wit... |
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Pneumomediastinum in COVID-19: a phenotype of severe COVID-19 pneumonitis? The results of the United Kingdom (POETIC) survey
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| BACKGROUND: There is an emerging understanding that coronavirus disease 2019 (COVID-19) is associated with increased incidence of pneumomediastinum. We aimed to determine its incidence among patients hospitalised with COVID-19 in the United Kingdom and describe factors associated with outcome. METHODS: A structured sur... |
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Hemorrhagic and ischemic stroke in patients with coronavirus disease 2019: incidence, risk factors, and pathogenesis - a systematic review and meta-analysis
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| Background: In this study, we aimed to determine the global prevalence, chronological order of symptom appearance, and mortality rates with regard to hemorrhagic and ischemic stroke in patients with coronavirus disease 2019 (COVID-19) and to discuss possible pathogeneses of hemorrhagic and ischemic stroke in individual... |
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Timing and clinical outcomes of tracheostomy in patients with COVID-19
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| In this retrospective multicentre cohort study that included 27 COVID-19 patients who underwent tracheostomy, the mean time between intubation and tracheostomy was 15.8 days and the negative conversion time of COVID-19 was 43.1 days. Eleven patients (40.7%) died of COVID-19 and the use of percutaneous dilatation trache... |
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On the Severity of COVID-19 in Intensive Care and the Role of Invasive Ventilation: A Proportion Meta-Analysis
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| Coronavirus Disease 2019 (COVID-19) is an emerging infectious pandemic,which has led to a worldwide public health emergency. The clinical spectrum of COVID-19 is varied, and has been explored in many studies. there is still a need to quantify the extent of the risk of developing the severe clinical manifestations of CO... |
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Cross-Sectional Survey on Long Term Sequelae of Pediatric COVID-19 among Italian Pediatricians
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| The persistence of symptoms after recovery from Coronavirus 2019 (COVID-19) is defined as long COVID, an entity that had occurred among adults but which is not yet well characterized in pediatric ages. The purpose of this work was to present some of the data from a survey addressed to Italian pediatricians concerning t... |
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Recovery from Coronavirus Disease 2019 among Older Adults in Post-Acute Skilled Nursing Facilities
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| OBJECTIVES: To examine functional outcomes of post-acute care for coronavirus disease 2019 (COVID-19) in skilled nursing facilities (SNFs). DESIGN: Retrospective cohort. SETTING AND PARTICIPANTS: Seventy-three community-dwelling adults ≥65 years of age admitted for post-acute care from 2 SNFs from March 15, 2020,... |
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[Clinical analysis of kidney injury in patients with COVID-19]
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| Objective: To investigate the relationship between novel coronavirus pneumonia (COVID-19) and kidney injury. Methods: A retrospective analysis was performed on COVID-19 confirmed patients in the Central Theater Command General Hospital of Chinese PLA on March 12, 2020. A total of 87 hospitalized COVID-19 confirmed pati... |
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Evaluation of prognostic/diagnostic value of hematological markers in the detection of inflammation in coronavirus disease: A review study
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| The Coronavirus infectious disease 2019 (COVID-19) has recently emerged as a pandemic and has endangered the lives of thousands of people worldwide. No specific treatment has been identified so far. However, the identification of diagnostic and prognostic factors in patients can be valuable for the application of preve... |
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Risk factors for critical illness and death among adult Brazilians with COVID-19
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| Abstract INTRODUCTION: Severe acute respiratory syndrome coronavirus 2 has infected more than 9,834,513 Brazilians up to February 2021. Knowledge of risk factors of coronavirus disease among Brazilians remains scarce, especially in the adult population. This study verified the risk factors for intensive care unit admis... |
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Myalgia as a symptom at hospital admission by severe acute respiratory syndrome coronavirus 2 infection is associated with persistent musculoskeletal pain as long-term post-COVID sequelae: a case-control study
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| ABSTRACT: This study investigated the association between COVID-related myalgia experienced by patients at hospital admission and the presence of post-COVID symptoms. A case-control study including patients hospitalised due to COVID-19 between February 20 and May 31, 2020, was conducted. Patients reporting myalgia and ... |
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Study of Disease Severity and Outcomes in COVID-19 Patients With Chronic Kidney Disease at a Tertiary Care Hospital in South India
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| Background: Coronavirus disease 2019 (COVID-19) disproportionately affects individuals with various comorbidities. Among these, chronic kidney disease (CKD) has been shown to be strongly associated with the progression to severe disease. This study aimed to assess the severity and disease outcomes in patients with COVI... |
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Age-standardized mortality rate and predictors of mortality among COVID-19 patients in Iran
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| BACKGROUND: To have a thorough understanding of epidemic surveillance, it is essential to broaden our knowledge of death tolls worldwide. This study aimed to determine the age-standardized mortality rate (ASMR) and predictors of mortality among coronavirus disease 2019 (COVID-19) patients. MATERIALS AND METHODS: In thi... |
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Comparison of Clinical Characteristics and Outcomes of Pediatric and Adult Patients with Coronavirus Disease 2019 in Shenzhen, China*
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| Objective Here we aimed to investigate the difference in clinical characteristics and outcomes between pediatric and adult patients with COVID-19. Methods A total of 333 consecutive patients with laboratory-confirmed SARS-CoV-2 infection treated in the departments of Internal medicine of Shenzhen Third People’s Hospita... |
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[Cardiac presentations in severe and critical coronavirus disease 2019]
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| OBJECTIVE: To investigate the cardiac presentations and the possible influencing factors of severe and critical coronavirus disease 2019 (COVID-19). METHODS: A retrospective study was conducted. Patients with severe and critical COVID-19 admitted to the Eighth People's Hospital of Guangzhou from January 21st to Februar... |
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Clinical characteristics of patients with COVID-19 admitted to the COVID-19 Emergency Field Hospital of Bangkalan, Indonesia (preprint)
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| Background: Following the surge of coronavirus disease 2019 (COVID-19) cases in the epicenter of East Java Province, this study aimed to determine the clinical characteristics of patients with COVID-19 at one of the emergency field hospitals in Indonesia. Methods: : This was a single-centered, retrospective descriptive... |
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Assessment of patient recognition of coronavirus disease 2019 (COVID-19)-associated olfactory loss and recovery: a longitudinal study
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| BACKGROUND: The clinical course of coronavirus disease 2019 (COVID-19) olfactory dysfunction remains poorly characterized, often limited by self-reported measures. Given the logistical challenges of psychophysical testing, understanding the longitudinal relationship between self-reported and quantitative measures can h... |
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Development and External Validation of a Delirium Prediction Model for Hospitalized Patients With Coronavirus Disease 2019
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| Background: The coronavirus disease 2019 pandemic has placed unprecedented stress on health systems and has been associated with elevated risk for delirium. The convergence of pandemic resource limitation and clinical demand associated with delirium requires careful risk stratification for targeted prevention efforts. ... |
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Long Covid-19: Proposed Primary Care Clinical Guidelines for Diagnosis and Disease Management
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| Long COVID-19 may be defined as patients who, four weeks after the diagnosis of SARS-Cov-2 infection, continue to have signs and symptoms not explainable by other causes. The estimated frequency is around 10% and signs and symptoms may last for months. The main long-term manifestations observed in other coronaviruses (... |
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Clinical Presentation and Outcomes of Hospitalized Children with COVID-19 in Mexico City (preprint)/ en
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| We describe the demographic, clinical, radiological and laboratory findings relating them also to the severity and clinical outcome of 129 children (0-18 years) which were admitted to a tertiary care pediatric hospital in Mexico City due to SARS- CoV-2 infection between April 1, 2020, to March 31, 2021. The infection w... |
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Arterial stiffness in acute COVID-19 and potential associations with clinical outcome
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| BACKGROUND: Coronavirus disease 2019 (COVID-19) interferes with the vascular endothelium. It is not known whether COVID-19 additionally affects arterial stiffness. METHODS: This case-control study compared brachial-ankle pulse wave (baPWV) and carotid-femoral pulse wave velocities (cfPWV) of acutely ill patients with a... |
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The first case of COVID-19 occurring as community-acquired pneumonia in Hokkaido, Japan and our preventive measures against nosocomial infection
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| We report a case of a 59-year-old man with coronavirus disease 2019 (COVID-19). He had visited a hospital for fever and cough and been treated with antibiotics for pneumonia in the right upper lobe. However, he gradually progressed to dyspnea and consulted our hospital. His chest radiographs showed bilateral pneumonia ... |
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Digestive system involvement and clinical outcomes among COVID-19 patients: A retrospective cohort study from Qatar
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| BACKGROUND: Coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 virus most commonly presents with respiratory symptoms. While gastrointestinal (GI) manifestations either at presentation or during hospitalization are also common, their impact on clinical outcomes is controve... |
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Impact of COVID-19 in patients with concurrent co-infections: a systematic review and meta-analyses.
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| BACKGROUND The burden and impact of secondary superadded infections in critically ill coronavirus disease (COVID-19) patients is widely acknowledged. However, there is a dearth of information regarding the impact of COVID-19 in patients with tuberculosis, HIV, chronic hepatitis, and other concurrent infections. This re... |
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A Clinical Study of Smell Disorders in COVID-19 Patients in a Tertiary Care Hospital in Pondicherry: A Cross Sectional Study
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| Anosmia and ageusia are the first and maybe the only symptom in patients affected with COVID-19 especially if the patient is paucisymptomatic. This aim of this study was to determine the demographic details of patients with anosmia, prevalence of anosmia and the time taken for it to resolve in patients who are positive... |
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Risk Stratification of Patients with COVID-19 Presenting at the Emergency Department
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| Background: Since the outbreak of the coronavirus disease 2019 (COVID-19) clinical characteristics and risk factors for unfavorable outcome of patients with CO |
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COVID-19, a tale of two peaks: patients’ characteristics, treatments, and clinical outcomes
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| Coronavirus 2019 disease (COVID-19) continues to challenge healthcare systems globally as many countries are currently experiencing an increase in the morbidity and mortality. Compare baseline characteristics, clinical presentation, treatments, and clinical outcomes of patients admitted during the second peak to those ... |
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Sixty-eight consecutive patients assessed for COVID-19 infection: Experience from a UK Regional infectious diseases Unit
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| BACKGROUND: Assessment of possible infection with SARS-CoV-2, the novel coronavirus responsible for COVID-19 illness, has been a major activity of infection services since the first reports of cases in December 2019. OBJECTIVES: We report a series of 68 patients assessed at a Regional Infection Unit in the UK. METHODS:... |
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Analysis of Epidemiological and Clinical Features in Older Patients With Coronavirus Disease 2019 (COVID-19) Outside Wuhan
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| BACKGROUND: The outbreak of coronavirus disease 2019 (COVID-19) has become a large threat to public health in China, with high contagious capacity and varied mortality. This study aimed to investigate the epidemiological and clinical characteristics of older patients with COVID-19 outside Wuhan. METHODS: A retrospectiv... |
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A Multicentre Study of 2019 Novel Coronavirus Disease Outcomes of Cancer Patients in Wuhan, China
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| Background: At present, there is a global pandemic of coronavirus disease 2019 (COVID-19) pneumonia. Two previous case series from China have suggested that cancer patients are at a higher risk of COVID-19 pneumonia, but the reports were limited by small numbers and few clinical information. Objective: To study clinica... |
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The effect of diabetes on mortality of COVID-19: A protocol for systematic review and meta-analysis
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| BACKGROUND: Novel coronavirus pneumonia (COVID-19) is a very serious and urgent infectious disease. With the development of global economy and the improvement of living standard, the incidence of diabetes is increasing year by year. And it is more common in the elderly. COVID-19 is associated with much chronic disease,... |
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Elevated liver enzymes in hospitalized patients with COVID-19 in Singapore
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| Liver dysfunction in patients with COVID-19 (coronavirus disease 2019) has been described. However, it is not clear if the presence of abnormal liver function tests at presentation was related to underlying undiagnosed liver disease, or a result of the viral infection. We retrospectively examined the first 554 consecut... |
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The arrival of COVID-19 in Brazil and the impact on coronary artery bypass surgery.
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| BACKGROUND AND AIM OF THE STUDY This study analyzed the arrival of coronavirus disease 2019 (COVID-19) in Brazil and its impact on coronary artery bypass grafting (CABG) surgery. METHODS Patients undergoing isolated CABG in six hospitals in Brazil were divided into two periods: pre-COVID-19 (March-May 2019, N = 468) an... |
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Risk factors associated with worse outcomes in COVID-19: a retrospective study in Saudi Arabia.
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| Background The rapid emergence of the novel coronavirus disease 2019 (COVID-19) has resulted in millions of infected patients and hundreds of thousands of deaths worldwide. Health care services delivery is being compromised due to the surge in the number of infected patients during this pandemic. Aims This study aimed ... |
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Coronavirus disease 2019 outcomes among patients with rheumatic diseases 6 months into the pandemic
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| OBJECTIVE: In earlier studies, patients with rheumatic and musculoskeletal disease (RMD) who got infected with COVID-19 had a higher risk of mechanical ventilation than comparators. We sought to determine COVID-19 outcomes among patients with RMD 6 months into the pandemic. METHODS: We conducted a cohort study at Mass ... |
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Postoperative mortality among surgical patients with COVID-19: a systematic review and meta-analysis
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| BACKGROUND: The coronavirus disease 2019 (COVID-19) pandemic puts perioperative providers and staff at risk of viral exposure to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) during aerosol-generating procedures, particularly in asymptomatic carriers.However, the perioperative risk for adverse outcomes i... |
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Clinical characteristics of neonates with coronavirus disease 2019 (COVID-19): a systematic review
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| This study aimed to summarize the existing literature on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in newborns to clarify the clinical features and outcomes of neonates with COVID-19. A systematic search was performed in PubMed, Embase, Cochrane Library, China National Knowledge Infrastruct... |
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