README.md

---
license: mit
tags:
  - PROTAC
  - drug-discovery
  - xgboost
  - cheminformatics
base_dataset: ailab-bio/TACK
---

# TACK — Bin Ensemble Models

Ensemble models for predicting PROTAC degradation activity (DC₅₀ < 100 nM & D*max* > 80%).

See the [TACK paper](https://arxiv.org/abs/2605.19579) and
[dataset](https://huggingface.co/datasets/ailab-bio/TACK) for details.