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+ ---
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+ license: mit
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+ tags:
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+ - PROTAC
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+ - drug-discovery
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+ - xgboost
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+ - cheminformatics
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+ base_dataset: ailab-bio/TACK
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+ ---
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+
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+ # TACK — Bin Ensemble Models
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+
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+ Ensemble models for predicting PROTAC degradation activity (DC₅₀ < 100 nM & D*max* > 80%).
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+ Contains `bin_caruana_ensemble` (22 models) and `bin_best_arch_ensemble` (25 models).
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+
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+ See the [TACK paper](https://arxiv.org/abs/2605.19579) and
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+ [dataset](https://huggingface.co/datasets/ailab-bio/TACK) for details.