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-Edit this `README.md` markdown file to author your organization card.
+# Oxford Protein Informatics Group (OPIG)
+
+**Computational research at the interface of protein science, immunology, and drug discovery**
+
+We are a research group led by [Charlotte Deane](https://www.stats.ox.ac.uk/~deane/) in the [Department of Statistics, University of Oxford](https://www.stats.ox.ac.uk/). Our work combines machine learning, structural biology, and cheminformatics to tackle fundamental problems in protein structure, antibody engineering, and small molecule drug design.
+
+---
+
+## Research Areas
+
+**Immunoinformatics** — Antibody and T-cell receptor structure prediction, developability assessment, repertoire analysis, and antigen binding.
+
+**Protein Structure** — Structure prediction, conformational dynamics, protein folding, and language models for genomic and proteomic sequences.
+
+**Small Molecules** — Structure-based drug design, molecular docking, generative models for drug-like molecules, and binding affinity prediction.
+
+---
+
+## Key Open-Source Tools & Databases
+
+| Tool | Description |
+|------|-------------|
+| [**SAbDab**](http://opig.stats.ox.ac.uk/webapps/newsabdab/sabdab) | Structural Antibody Database — all antibody structures from the PDB, updated weekly |
+| [**OAS**](http://opig.stats.ox.ac.uk/webapps/oas) | Observed Antibody Space — billions of antibody sequences from immune repertoire sequencing studies |
+| [**STCRDab**](http://opig.stats.ox.ac.uk/webapps/stcrdab) | Structural T-Cell Receptor Database |
+| [**CoV-AbDab**](http://opig.stats.ox.ac.uk/webapps/coronavirus) | Coronavirus Antibody Database — antibodies targeting SARS-CoV-2 and related coronaviruses |
+| [**AbLang**](https://github.com/oxpig/AbLang) | Antibody language model for sequence infilling and representation |
+| [**ANARCI**](https://github.com/oxpig/anarci) | Antibody and TCR sequence numbering and annotation |
+| [**ABlooper**](https://github.com/oxpig/ABlooper) | Fast, accurate CDR loop structure prediction |
+| [**Paragraph**](https://github.com/oxpig/Paragraph) | Graph neural network-based antibody paratope prediction |
+| [**MolSnapper**](https://github.com/oxpig/MolSnapper) | Conditioning diffusion models for structure-based drug design |
+| [**STRIFE**](https://github.com/oxpig/STRIFE) | Fragment elaboration using pharmacophoric constraints |
+| [**CaLM**](https://github.com/oxpig/CaLM) | Codon-aware language model for protein engineering |
+
+All of our open-source code lives at **[github.com/oxpig](https://github.com/oxpig)**.
+
+---
+
+## Get Involved
+
+- 🌐 **Website**: [opig.stats.ox.ac.uk](https://opig.stats.ox.ac.uk)
+- 📝 **Blog**: [blopig.com/blog](https://blopig.com/blog) — tutorials, methods explainers, and research updates
+- 🦋 **Bluesky**: [@opig.stats.ox.ac.uk](https://bsky.app/profile/opig.stats.ox.ac.uk)
+- 🐦 **X/Twitter**: [@OPIGlets](https://x.com/OPIGlets)
+- 💼 **LinkedIn**: [Oxford Protein Informatics Group](https://www.linkedin.com/company/oxford-protein-informatics-group-opig/)
+
+Interested in a DPhil or postdoc? See our [current research](https://opig.stats.ox.ac.uk/research) and [get in touch](https://opig.stats.ox.ac.uk/contact).