Advancement and Innovation in Measurement of Language Development and Predictors (R01 Clinical Trial Not Allowed)

For profit organizations other than small businesses; State governments; Others (see text field entitled "Additional Information on Eligibility" for clarification); Native American tribal organizations (other than Federally recognized tribal governments); Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Small businesses; City or township governments; Native American tribal governments (Federally recognized); Public housing authorities/Indian housing authorities; Independent school districts; County governments; Special district governments; Private institutions of higher education; Public and State controlled institutions of higher education; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education

The purpose of this notice of funding opportunity (NOFO) is to encourage community-engaged research that broadens the conceptualization of qualities of the environment that can support language development in children and that focuses on the development of novel measures of childrens language development. The overall goal is to build the number of strengths-focused, culturally and linguistically responsive, and generalizable toolsto further our understanding of childrens language development and/or impairment, and predictors thereof.


Advancement and Innovation in Measurement of Language Development and Predictors (R21 Clinical Trial Not Allowed)

Health; Income Security and Social Services

Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Independent school districts; City or township governments; State governments; Native American tribal governments (Federally recognized); Native American tribal organizations (other than Federally recognized tribal governments); For profit organizations other than small businesses; Special district governments; Small businesses; County governments; Private institutions of higher education; Public and State controlled institutions of higher education; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification); Public housing authorities/Indian housing authorities

Official Grants.gov search and detail API row; no applicant-fit screening was applied.

Award size not listed in Grants.gov synopsis; verify NOFO


D-START: Data Science Track Award for Research Transition (D/START) (R03-Clinical Trial Optional)

Included from broad Grants.gov search; detail not fetched yet.


FAA Aviation Research Grants Program


Interventions to Reduce Sleep Health Disparities (R01 - Clinical Trials Optional)

For profit organizations other than small businesses; Private institutions of higher education; Independent school districts; Others (see text field entitled "Additional Information on Eligibility" for clarification); County governments; Public and State controlled institutions of higher education; City or township governments; Public housing authorities/Indian housing authorities; Native American tribal organizations (other than Federally recognized tribal governments); Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Native American tribal governments (Federally recognized); Small businesses; State governments; Special district governments

This PAR is being reissued in accordance with the simplified review criteria in effect for application due dates after January 25, 2025. The objective of this funding opportunity is to support non-pharmacological interventions to promote sleep health, reduce sleep health disparities, and examine sleep as a modifiable factor to reduce health disparities for other health outcomes among populations that experience health disparities.


Investigator Initiated Innovation in Computational Genomics and Data Science (R01 Clinical Trial Not Allowed)

Public housing authorities/Indian housing authorities; Special district governments; Public and State controlled institutions of higher education; State governments; City or township governments; Native American tribal governments (Federally recognized); Independent school districts; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Private institutions of higher education; County governments; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; For profit organizations other than small businesses; Others (see text field entitled "Additional Information on Eligibility" for clarification); Native American tribal organizations (other than Federally recognized tribal governments); Small businesses

The purpose of this funding opportunity announcement (FOA) is to invite applications for a broad range of research efforts in computational genomics, data science, statistics, and bioinformatics relevant to one or both of basic or clinical genomic science, and broadly applicable to human health and disease. This FOA supports fundamental genomics research developing innovative analytical methodologies and approaches, early-stage development of tools and software, and refinement or hardening of software and tools of high value to the biomedical genomics community. Work supported under this FOA should be enabling for genomics and be generalizable or broadly applicable across diseases and bio...


Investigator Initiated Innovation in Computational Genomics and Data Science (R21 Clinical Trial Not Allowed)

For profit organizations other than small businesses; State governments; Public housing authorities/Indian housing authorities; County governments; City or township governments; Special district governments; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Public and State controlled institutions of higher education; Private institutions of higher education; Small businesses; Native American tribal governments (Federally recognized); Native American tribal organizations (other than Federally recognized tribal governments); Independent school districts; Others (see text field entitled "Additional Information on Eligibility" for clarification)


NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed)


NICHD Resource Program Grants in Bioinformatics (P41 Clinical Trial Not Allowed)

City or township governments; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Private institutions of higher education; State governments; Public and State controlled institutions of higher education; Native American tribal organizations (other than Federally recognized tribal governments); Special district governments; Native American tribal governments (Federally recognized); Small businesses; County governments; Public housing authorities/Indian housing authorities; Others (see text field entitled "Additional Information on Eligibility" for clarification); Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; For profit organizations other than small businesses; Independent school districts

The purpose of this Notice of Funding Opportunity (NOFO) is to support the continued operation, maintenance, and dissemination of unique database bioinformatics resources that are of major importance to the research community using animal models of embryonic developmental processes. These grants will support ongoing development and enhancement of the resources, user training and services, provision of community generated data storage and curation, wide dissemination of the tools and/or resources, and expansion of interoperability with other NIH bioinformatics resources.


Limited Competition: Mentored Research Career Development Program Award in Clinical and Translational Science Awards (CTSA) Program (K12 Clinical Trial Optional)

Public and State controlled institutions of higher education

The National Center for Advancing Translational Sciences (NCATS) will award Institutional Research Career Development (K12) programs through the Clinical and Translational Science Awards (CTSA). The purpose of this Notice of Funding Opportunity (NOFO) is to encourage institutions to propose creative and innovative institutional research career development programs designed to prepare an outstanding heterogeneous pool of promising later stage postdoctoral fellows and junior faculty scholars who have made a commitment to independent clinical and translational science research careers (i.e., tenure-track or equivalent faculty positions)to facilitate their timely career advancementand continu...


Limited Competition: Ruth L. Kirschstein National Research Service Award (NRSA) Postdoctoral Research Training Grant for the Clinical and Translational Science Awards (CTSA) Program (T32 Clinical Trial Not Allowed)


Limited Competition: Ruth L. Kirschstein National Research Service Award (NRSA) Predoctoral Research Training Grant for the Clinical and Translational Science Awards (CTSA) Program (T32 Clinical Trial Not Allowed)

The National Center for Advancing Translational Sciences (NCATS) will award Ruth L. Kirschstein National Research Service Award (NRSA) Predoctoral Institutional Research Training Grants for the Clinical and Translational Science Awards (CTSA) Program (T32) to eligibleinstitutions to create, provide, and disseminate clinical and translational science training and career support programs for individuals seeking a PhD or an equivalent research health professional degree and help ensure a heterogenous pool of clinical and translational scientist trainees who are equipped with the knowledge, skills and abilities (KSAs) to advance diagnostics, therapeutics, clinical interventions, and behaviora...


Research Experiences and/or Mentoring Networks through Research Education to Enhance Clinician-Scientists' Participation in NIDCDs Research (R25 Clinical Trial Not Allowed)

Independent school districts; For profit organizations other than small businesses; Small businesses; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Native American tribal organizations (other than Federally recognized tribal governments); Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; County governments; State governments; Others (see text field entitled "Additional Information on Eligibility" for clarification); Public and State controlled institutions of higher education; Private institutions of higher education; City or township governments; Public housing authorities/Indian housing authorities; Special district governments; Native American tribal governments (Federally recognized)

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The overarching goal of this R25 program is to support educational activities that help recruit individuals with specific specialty or disciplinary backgrounds to research careers in biomedical, behavioral and clinical sciences.


CHEERS Open Period 1 - All Technical Areas


CHEERS Open Period 2 - All Technical Areas


DOD Defense Health Agency (DHA) Research & Development FY23-FY27 BROAD AGENCY ANNOUNCEMENT for Extramural Medical Research


NIDCD Research Grants for Translating Basic Research into Clinical Practice (R01 Clinical Trial Optional)

State governments; City or township governments; Native American tribal organizations (other than Federally recognized tribal governments); Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Small businesses; Private institutions of higher education; Independent school districts; County governments; Others (see text field entitled "Additional Information on Eligibility" for clarification); Native American tribal governments (Federally recognized); Public housing authorities/Indian housing authorities; Special district governments; Public and State controlled institutions of higher education; For profit organizations other than small businesses; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education

This Funding Opportunity Announcement (FOA) is intended to provide an avenue for basic scientists, clinicians and clinical scientists to jointly initiate and conduct translational research projects which translate basic research findings into clinical tools for better human health. The scope of this FOA includes a range of activities to encourage translation of basic research findings which will impact the diagnosis, treatment and prevention of communication disorders. Connection to the clinical condition must be clearly established and the outcomes of the grant must have practical clinical impact.


NCI Pathway to Independence Award (K99/R00 Clinical Trial Not Allowed)

For profit organizations other than small businesses; Special district governments; Native American tribal governments (Federally recognized); Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; City or township governments; Private institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification); Public housing authorities/Indian housing authorities; Public and State controlled institutions of higher education; State governments; County governments; Independent school districts; Native American tribal organizations (other than Federally recognized tribal governments); Small businesses

The purpose of the NCI Pathway to Independence Award (K99/R00) program is to facilitate a timely transition of talented postdoctoral researchers with a research and/or clinical doctorate degree from mentored, postdoctoral research positions to independent, tenure-track or equivalent faculty positions. The program will provide independent NCI research support during this transition in order to help awardees to launch competitive, independent research careers.


NCI Pathway to Independence Award (K99/R00 Clinical Trial Required)

Public and State controlled institutions of higher education; State governments; Private institutions of higher education; Native American tribal governments (Federally recognized); Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; City or township governments; Native American tribal organizations (other than Federally recognized tribal governments); Independent school districts; Public housing authorities/Indian housing authorities; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; For profit organizations other than small businesses; Small businesses; Others (see text field entitled "Additional Information on Eligibility" for clarification); Special district governments; County governments


Confirmatory Efficacy Clinical Trials of Non-Pharmacological and Pharmacological Interventions for Mental Disorders (R01 Clinical Trial Required)

Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Native American tribal governments (Federally recognized); Others (see text field entitled "Additional Information on Eligibility" for clarification); Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; County governments; City or township governments; Special district governments; Public and State controlled institutions of higher education; Native American tribal organizations (other than Federally recognized tribal governments); State governments; For profit organizations other than small businesses; Independent school districts; Public housing authorities/Indian housing authorities; Private institutions of higher education; Small businesses

Confirmatory Efficacy Clinical Trials of Non-Pharmacological Interventions for Mental Disorders (R01 Clinical Trial Required). As part of NIMH's clinical trials pipeline NOFOs, this announcement supports confirmatory efficacy testing of non pharmacological therapeutic and preventive interventions for mental disorders in adults and children that address unmet therapeutic needs, and are consistent with the NIMH emphasis on the experimental therapeutics approach. In this approach, clinical trials should be designed to increase knowledge of the relationship between underlying disease processes and the mechanisms of action through which any intervention produces therapeutic change.


Public housing authorities/Indian housing authorities; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Private institutions of higher education; Small businesses; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Independent school districts; Native American tribal governments (Federally recognized); For profit organizations other than small businesses; City or township governments; Native American tribal organizations (other than Federally recognized tribal governments); Others (see text field entitled "Additional Information on Eligibility" for clarification); County governments; Public and State controlled institutions of higher education; State governments; Special district governments

Development of Psychosocial Therapeutic and Preventive Interventions for Mental Disorders (R33 Clinical Trial Required). As part of NIMH's clinical trials pipeline, this NOFO encourages pilot research developing and testing novel psychosocial interventions and/or targets. Consistent with NIMH's emphasis on the experimental therapeutics approach to intervention development, it intends to speed the translation of emergent research in basic, behavioral, cognitive, affect, and neuropsychological science into preventative or therapeutic interventions. This RFA will provide up to three years of support to replicate target engagement from prior studies and to test the association between target...


Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Public and State controlled institutions of higher education; Independent school districts; Native American tribal organizations (other than Federally recognized tribal governments); Special district governments; Public housing authorities/Indian housing authorities; For profit organizations other than small businesses; County governments; Native American tribal governments (Federally recognized); Private institutions of higher education; State governments; City or township governments; Others (see text field entitled "Additional Information on Eligibility" for clarification); Small businesses; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education

Development of Psychosocial Therapeutic and Preventive Interventions for Mental Disorders (R61/R33 Clinical Trial Required). As part of NIMH's clinical trials pipeline, this NOFO encourages pilot research developing and testing novel psychosocial interventions and/or targets. Consistent with NIMH's emphasis on the experimental therapeutics approach to intervention development, it intends to speed the translation of emergent research in basic, behavioral, cognitive, affect, and neuropsychological science into preventative or therapeutic interventions. This RFA will provide up to two years of support for evaluation of target engagement and establishment of intervention parameters, and up to...


Early Stage Testing of Pharmacologic or Neuromodulatory Device-based Interventions for the Treatment of Mental Disorders (R33- Clinical Trial Required)

County governments; Native American tribal governments (Federally recognized); Special district governments; City or township governments; State governments; Native American tribal organizations (other than Federally recognized tribal governments); Independent school districts; Small businesses; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Private institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification); Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Public housing authorities/Indian housing authorities; For profit organizations other than small businesses; Public and State controlled institutions of higher education

NIMH requires an experimental therapeutics approach for the development and testing of therapeutic interventions, in which studies both evaluate the clinical effect of an intervention and generate information about the mechanisms underlying a disorder or an intervention response. As part of NIMHs Clinical Trial Pipeline, this NOFO encourages early stage testing of pharmacologic interventions with novel mechanisms of actions or device-based interventions. More specifically, this NOFO is intended to support early stage testing of pharmacologic or device-based interventions using a protocol design where the presumed mechanism of action of the intervention is adequately tested, to provide mea...


Early Stage Testing of Pharmacologic or Neuromodulatory Device-based Interventions for the Treatment of Mental Disorders (R61/R33 Clinical Trial Required)


Effectiveness Trials to Test Mental Health System Interventions (R61/R33 Clinical Trial Required)

Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; County governments; City or township governments; Public housing authorities/Indian housing authorities; Independent school districts; Public and State controlled institutions of higher education; Native American tribal organizations (other than Federally recognized tribal governments); For profit organizations other than small businesses; Native American tribal governments (Federally recognized); Small businesses; Special district governments; Private institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification); Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; State governments

This R61/R33 concept complements NIMHs suite of clinical trial NOFOs by supporting feasibility and infrastructure development (R61) followed by well-powered clinical trials (R33) to test the effectiveness of system interventions and strategies for improving the organization, delivery, coordination, and clinical and functional outcomes of mental health services. System interventions - which may span, for example, structural, policy, organizational, and interpersonal domains - attend to issues about the access, equity, engagement/utilization, value (cost/financing), management, or quality and safety of mental health services, with the goal of improved care processes and clinical and functio...


Full-Scale Hybrid Effectiveness-Implementation Trials for Mental Health Interventions (R01 - Clinical Trial Required)

Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Public housing authorities/Indian housing authorities; County governments; Public and State controlled institutions of higher education; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; For profit organizations other than small businesses; Others (see text field entitled "Additional Information on Eligibility" for clarification); State governments; Private institutions of higher education; Special district governments; Independent school districts; Native American tribal organizations (other than Federally recognized tribal governments); City or township governments; Native American tribal governments (Federally recognized); Small businesses

Clinical Trials to Test the Effectiveness of Treatment, Preventive, and Services Interventions (R01 Clinical Trial Required). This NOFO is a key element of NIMHs set of NOFOs to support clinical trials research across the intervention development and testing pipeline. The NOFO supports (1) clinical trials to test the effectiveness of optimized therapeutic and preventive interventions for use in community and practice settings; and (2) clinical trials to evaluate the effectiveness of patient-, provider-, organizational-, or systems-level services interventions to improve access, continuity, quality, equity, and/or value of mental health services. This NOFO is intended to support trials tha...


NIDCD Early Career Research(ECR) Award (R21 Clinical Trial Optional)


Pilot Hybrid Effectiveness-Implementation Trials for Mental Health Interventions (R01 Clinical Trial Required)

Private institutions of higher education; Special district governments; Public and State controlled institutions of higher education; City or township governments; State governments; Small businesses; Native American tribal governments (Federally recognized); Others (see text field entitled "Additional Information on Eligibility" for clarification); Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Native American tribal organizations (other than Federally recognized tribal governments); Independent school districts; County governments; Public housing authorities/Indian housing authorities; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; For profit organizations other than small businesses

Pilot Effectiveness Trials for Treatment, Preventive and Services Interventions (R01 Clinical Trial Required). As part of NIMH's clinical trials pipeline NOFOs, this announcement encourages pilot effectiveness studies focused on 1) optimizing the effectiveness of preventive and therapeutic interventions with previously demonstrated efficacy, for use with broader target populations or for use in community practice settings, and 2) developing and preliminary testing innovative services interventions. Consistent with the NIMH experimental therapeutics approach, this NOFO is intended to support pilot studies of intervention effectiveness or service delivery approaches that explicitly address...


NEI Research Grant for Vision-Related Secondary Data Analysis (R21 Clinical Trial Not Allowed)

Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Independent school districts; State governments; Public housing authorities/Indian housing authorities; County governments; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Native American tribal organizations (other than Federally recognized tribal governments); Small businesses; Private institutions of higher education; City or township governments; Native American tribal governments (Federally recognized); Others (see text field entitled "Additional Information on Eligibility" for clarification); Special district governments; Public and State controlled institutions of higher education; For profit organizations other than small businesses

The goal of this funding opportunity announcement (FOA) is to fund meritorious vision-related research projects that involve secondary data analyses using existing database resources. The development of statistical methodology necessary for improving methods to analyze vision health data using existing vision data may also be proposed.


Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Assay Development and Neurotherapeutic Agent Identification (R61/R33 Clinical Trial Not Allowed)


Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Development and Validation of Model Systems to Facilitate Neurotherapeutic Discovery (R61/R33 Clinical Trial Not Allowed)


Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Neurotherapeutic Agent Characterization and In vivo Efficacy Studies (R61/R33 Clinical Trial Not Allowed)

Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Private institutions of higher education; Small businesses; For profit organizations other than small businesses; Others (see text field entitled "Additional Information on Eligibility" for clarification); City or township governments; Independent school districts; County governments; Native American tribal organizations (other than Federally recognized tribal governments); Public housing authorities/Indian housing authorities; Native American tribal governments (Federally recognized); State governments; Special district governments; Public and State controlled institutions of higher education

Reissue PAR-21-122. This NOFO provides funding to conduct pharmacodynamic, pharmacokinetic, and in vivo efficacy studies to demonstrate that proposed therapeutic agent(s) have sufficient biological activity to warrant further development to treat neurological or neuromuscular disorders that fall under the NINDS mission. Therapeutic agents include small molecules, biologics or biotechnology-derived products. This FOA is part of a suite of Innovation Grants to Nurture Initial Translational Efforts (IGNITE) to advance projects to the point where they can meet the entry criteria for the Blueprint Neurotherapeutics Network or other translational programs.


Cancer Prevention and Control Clinical Trials Planning Grant Program (R34 Clinical Trials Optional)

Others (see text field entitled "Additional Information on Eligibility" for clarification); Native American tribal governments (Federally recognized); City or township governments; Independent school districts; Special district governments; Public and State controlled institutions of higher education; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; State governments; Public housing authorities/Indian housing authorities; Small businesses; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Private institutions of higher education; Native American tribal organizations (other than Federally recognized tribal governments); County governments; For profit organizations other than small businesses

The purpose of this FOA is to facilitate well planned clinical trials across the cancer prevention and control spectrum aimed at improving prevention/ interception, cancer-related health behaviors, screening, early detection, healthcare delivery, management of treatment-related symptoms, supportive care, and the long-term outcomes of cancer survivors. Although the scientific literature or preliminary data may provide the rationale for conducting a clinical trial, investigators often lack critical information about the study population, accrual challenges, intervention, outcome/ endpoints, data/statistical challenges or operational risks necessary to finalize the trial protocol completely....


Advancing HIV/AIDS Research within the Mission of the NIDCD (R01 Clinical Trial Optional)


Priority HIV/AIDS Research within the Mission of NIDDK (R01 Clinical Trial Optional)


BRAIN Initiative: Theories, Models and Methods for Analysis of Complex Data from the Brain (R01 Clinical Trial Not Allowed)


Career Transition Award for NINDS Intramural Clinician-Scientists (K22 Clinical Trial Not Allowed)

Independent school districts; Special district governments; Small businesses; For profit organizations other than small businesses; Native American tribal governments (Federally recognized); Others (see text field entitled "Additional Information on Eligibility" for clarification); City or township governments; County governments; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Private institutions of higher education; Public housing authorities/Indian housing authorities; Public and State controlled institutions of higher education; Native American tribal organizations (other than Federally recognized tribal governments); Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; State governments

The objective of the NIH Career Transition Award (K22) is to provide support to outstanding basic or clinical investigators to develop their independent research skills through a two phase program: an initial period involving an intramural appointment at the NIH and a final period of support at an extramural institution. This NINDS K22 is specifically designed to facilitate the transition of NINDS intramural neurologist- and neurosurgeon-scientists to independent, academic faculty positions that support clinician-scientists to engage in independently funded scientific research as well as clinical activities.


Career Transition Award for NINDS Intramural Clinician-Scientists (K22 Clinical Trial Required)

Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Independent school districts; Public and State controlled institutions of higher education; State governments; Native American tribal organizations (other than Federally recognized tribal governments); Small businesses; County governments; Public housing authorities/Indian housing authorities; For profit organizations other than small businesses; Others (see text field entitled "Additional Information on Eligibility" for clarification); Private institutions of higher education; City or township governments; Special district governments; Native American tribal governments (Federally recognized); Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education


NIA Academic Leadership Career Award (K07 Independent Clinical Trial Not Allowed)

Others (see text field entitled "Additional Information on Eligibility" for clarification); Public housing authorities/Indian housing authorities; Small businesses; City or township governments; State governments; Private institutions of higher education; Special district governments; For profit organizations other than small businesses; Native American tribal governments (Federally recognized); County governments; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Native American tribal organizations (other than Federally recognized tribal governments); Independent school districts; Public and State controlled institutions of higher education

The objective of the NIA Academic Leadership Career Award (K07) is to provide support for established investigators who have the expertise and leadership skills to enhance aging and/or Alzheimer's Disease (AD) and Alzheimers Disease Related Dementias (ADRD)research capacity within their academic institution. Through this award, investigators will endeavor to develop research and educational infrastructure, mentorship, and career development activities in support of new or emerging areas of aging and/or AD/ADRDresearch. These may include, but are not limited to, courses, curricula, research support, pilot funding, travel awards, visiting scholars, or networks. This Notice of Funding Opport...


NIDA Research Education Program for Clinical Researchers and Clinicians (R25 Clinical Trial Not Allowed)

Small businesses; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Public housing authorities/Indian housing authorities; State governments; City or township governments; Native American tribal governments (Federally recognized); For profit organizations other than small businesses; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification); County governments; Special district governments; Public and State controlled institutions of higher education; Independent school districts; Native American tribal organizations (other than Federally recognized tribal governments); Private institutions of higher education

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The over-arching goal of this NIDA R25 program is to support educational activities that complement and/or enhance the training of a workforce to meet the nations biomedical, behavioral and clinical research needs. This NOFO is intended to support research education activities that enhance the knowledge of substance use and substance use disorder research. The program is intended for those in clinically focused careers and/or those training for careers as clinicians/health service providers, clinical researchers, or optimally a combination of the two. This mechanism may not be...


Toward Translation of Nanotechnology Cancer Interventions (TTNCI; R01 Clinical Trial Not Allowed)

Public housing authorities/Indian housing authorities; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Independent school districts; Public and State controlled institutions of higher education; Small businesses; Others (see text field entitled "Additional Information on Eligibility" for clarification); State governments; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; County governments; Native American tribal organizations (other than Federally recognized tribal governments); Special district governments; Private institutions of higher education; City or township governments; Native American tribal governments (Federally recognized); For profit organizations other than small businesses

Through this Notice of Funding Opportunity (NOFO), entitled "Toward Translation of Nanotechnology Cancer Interventions" (TTNCI), the National Cancer Institute (NCI) encourages applications for advanced pre-clinical research, supporting translation of nanotechnology-based cancer diagnostics and therapeutics. TTNCI awards are designed to mature experimental nanomedicines relying on nanoparticles and nano-devices which demonstrate strong potential to improve cancer treatment effectiveness due to the combination of nanoparticle/nano-device structural design and/or therapeutic/diagnostic cargo which is delivered. TTNCI awards are expected to enable further development of proposed nanotechnolog...


Advancing HIV/AIDS Research within the Mission of the NIDCD (R21 Clinical Trial Optional)


Basic Research in Cancer Health Disparities (R21 Clinical Trial Not Allowed)


Innovative Screening Approaches and Therapies for Screenable Disorders in Newborns (R01 - Clinical Trial Optional)

Special district governments; Public housing authorities/Indian housing authorities; City or township governments; Private institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification); County governments; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Independent school districts; Public and State controlled institutions of higher education; Native American tribal organizations (other than Federally recognized tribal governments); Native American tribal governments (Federally recognized); For profit organizations other than small businesses; State governments; Small businesses; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education

This FOA encourages research relevant to the development of novel screening approaches and/or therapeutic interventions for potentially fatal or disabling conditions that have been identified through newborn screening, as well as for "high priority" genetic conditions where screening may be possible in the near future.Having an accurate screening test, as well as demonstrating the benefits of early intervention or treatment, are important criteria for including a condition on a newborn screening panel. This FOA defines a "high priority" condition as one where screening is not currently recommended, but infants with the condition would significantly benefit from early identification and tr...


Innovative Screening Approaches and Therapies for Screenable Disorders in Newborns (R21 - Clinical Trial Optional)

Others (see text field entitled "Additional Information on Eligibility" for clarification); Special district governments; Public housing authorities/Indian housing authorities; Independent school districts; County governments; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Native American tribal governments (Federally recognized); Native American tribal organizations (other than Federally recognized tribal governments); Private institutions of higher education; Small businesses; For profit organizations other than small businesses; City or township governments; Public and State controlled institutions of higher education; State governments


Pilot Projects Investigating Understudied Proteins Associated with Rare Diseases (R03 Clinical Trial Not Allowed)

Special district governments; County governments; Private institutions of higher education; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Independent school districts; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Small businesses; Native American tribal organizations (other than Federally recognized tribal governments); Public housing authorities/Indian housing authorities; For profit organizations other than small businesses; Public and State controlled institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification); Native American tribal governments (Federally recognized); City or township governments; State governments

The purpose of this notice of funding opportunity (NOFO) is to solicit applications for pilot projects to elucidate a role for understudied proteins in rare disease. Awards will support generation of preliminary data and/or tools around eligible understudied protein(s). A list of eligible proteins is provided and are members of druggable protein families that have a known association with a rare disease. This NOFO is intended to jumpstart research on understudied proteins that are associated with rare diseases and provide applicants with sufficient funding to perform basic biochemical and/or biological work to further the characterization of understudied proteins within the context of rar...


Pilot Studies of Biological, Behavioral and Social Mechanisms Contributing to HIV Pathogenesis Within the Mission of NIDDK (R21 Clinical Trial Not Allowed)


Chemical Countermeasures Research Program (CCRP) Initiative: Basic Research on The Deleterious Effects of Acute Exposure to Ultra-Potent Synthetic (UPS) Opioids (R01 Clinical Trial Not Allowed)


DEVCOM ARMY RESEARCH LABORATORY BROAD AGENCY ANNOUNCEMENT FOR FOUNDATIONAL RESEARCH


Accelerating the Pace of Substance Use Research Using Existing Data (R01 Clinical Trial Not Allowed)


Accelerating the Pace of Substance Use Research Using Existing Data (R21 Clinical Trial Not Allowed)


Catalyze Product Definition Medical Device prototype design/testing and disease target identification and assay development (R61/R33 - Clinical Trial Not Allowed)

City or township governments; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification); Native American tribal organizations (other than Federally recognized tribal governments); Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Small businesses; State governments; For profit organizations other than small businesses; Special district governments; Private institutions of higher education; Public and State controlled institutions of higher education; Public housing authorities/Indian housing authorities; County governments; Independent school districts; Native American tribal governments (Federally recognized)

The goal of the NHLBI Catalyze Program is to provide a comprehensive suite of support and services to facilitate the transition of basic science discoveries into viable diagnostic and therapeutic candidates that have been cleared for human testing, and to develop translational researchers fluent in product development and entrepreneurship. This specific Catalyze Product Definition initiative will provide the early stage translational support needed for the activities required to develop and test device prototypes, identify diagnostic disease targets and develop associated assays, and develop research tools to treat HLBS diseases and disorders. This is a phased initiative for early stage p...


Catalyze: Enabling Technologies and Transformative Platforms for HLBS Research (R33 - Clinical Trials Not Allowed)


Catalyze: Product Definition Medical Device Prototype Optimization (R33 - Clinical Trial Not Allowed)


Catalyze: Product Definition for Small Molecules, Biologics and Combination Products - Target Identification and Validation, and Preliminary Product/Lead Series Identification (R61/R33 Clinical Trials Not Allowed)


Catalyze: Product Definition for Small Molecules, Biologics, and Combination Products - Preliminary Product/Lead Series Identification and Combination Product Prototype (R33 - Clinical Trial Not Allowed)


DEVCOM ANALYSIS CENTER BROAD AGENCY ANNOUNCEMENT FOR APPLIED RESEARCH


Stimulating Hematology Investigation: New Endeavors (SHINE) (R01 Clinical Trial Not Allowed)


Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Not Allowed)

Education; Environment; Food and Nutrition; Health; Income Security and Social Services

Public and State controlled institutions of higher education; Private institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification)

The purpose of this Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutionsis to support small scale research grants at institutions that do not receive substantial funding from the NIH, with an emphasis on providing biomedical research experiences primarily for undergraduate students, and enhancing the research environment at applicant institutions. Eligible institutions must award baccalaureate science degrees and have received no more than $6 million dollars per year of NIH support (in both direct and F and A/indirect costs) in 4 of the last 7 fiscal years. For institutions composed of multiple schools and colleges, the $6 million funding limit is based on the...


Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Required)

Education; Health; Income Security and Social Services

Public and State controlled institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification); Private institutions of higher education

The purpose of this Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions is to support small scale research grants at institutions that do not receive substantial funding from the NIH, with an emphasis on providing biomedical research experiences primarily for undergraduate students and enhancing the research environment at applicant institutions. Eligible institutions must award baccalaureate science degrees and have received no more than $6 million dollars per year of NIH support (in both direct and F and A/indirect costs) in 4 of the last 7 fiscal years. For institutions composed of multiple schools and colleges, the $6 million funding limit is based on the...


Academic-Industrial Partnerships for Translation of Technologies for Diagnosis and Treatment (R01 - Clinical Trial Not Allowed)

Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Private institutions of higher education; Public and State controlled institutions of higher education; For profit organizations other than small businesses; Others (see text field entitled "Additional Information on Eligibility" for clarification); Special district governments; City or township governments; County governments; State governments; Native American tribal organizations (other than Federally recognized tribal governments); Independent school districts; Public housing authorities/Indian housing authorities; Small businesses; Native American tribal governments (Federally recognized); Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) intends to stimulate efforts to translate scientific discoveries and engineering developments into methods or tools that address problems in basic research to understand disease, or in applied research to assess risk, detect, prevent, diagnose, treat, and/or manage disease. The rationale is to deliver new capabilities to meet evolving requirements for technologies and methods relevant to the advance of research and delivery of care in pre-clinical, clinical and non-clinical settings, domestic or foreign, for conditions and diseases within the missions of participating institutes.


Academic-Industrial Partnerships for Translation of Technologies for Diagnosis and Treatment (R01 - Clinical Trial Optional)

Small businesses; Independent school districts; Others (see text field entitled "Additional Information on Eligibility" for clarification); County governments; Public housing authorities/Indian housing authorities; City or township governments; For profit organizations other than small businesses; Private institutions of higher education; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; State governments; Native American tribal organizations (other than Federally recognized tribal governments); Special district governments; Native American tribal governments (Federally recognized); Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Public and State controlled institutions of higher education


Advancing Healthcare for Older Adults from Populations that Experience Health Disparities (R01 - Clinical Trial Optional)


Basic Research in Cancer Health Disparities (R01 Clinical Trial Not Allowed)

City or township governments; Native American tribal governments (Federally recognized); County governments; Small businesses; Public housing authorities/Indian housing authorities; Public and State controlled institutions of higher education; Native American tribal organizations (other than Federally recognized tribal governments); Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Private institutions of higher education; Independent school districts; State governments; Others (see text field entitled "Additional Information on Eligibility" for clarification); For profit organizations other than small businesses; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Special district governments

This Notice of Funding Opportunity (NOFO) encourages grant applications from investigators interested in conducting basic, mechanistic research into the biological/genetic causes of cancer health disparities. These research project grants will support innovative studies designed to investigate biological/genetic bases of cancer disparities, such as (1) mechanistic studies of biological factors associated with cancer disparities, including those related to basic research in cancer biology or cancer prevention strategies, (2) the development and testing of new methodologies and models, and (3) secondary data analyses. This NOFO is also designed to aid and facilitate the growth of a nationwi...


Clinical Characterization of Cancer Therapy-induced Adverse Sequelae and Mechanism-based Interventional Strategies (R01 Clinical Trial Optional)

Others (see text field entitled "Additional Information on Eligibility" for clarification); Native American tribal organizations (other than Federally recognized tribal governments); Special district governments; Public and State controlled institutions of higher education; County governments; City or township governments; State governments; Private institutions of higher education; Independent school districts; Small businesses; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Public housing authorities/Indian housing authorities; Native American tribal governments (Federally recognized); Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; For profit organizations other than small businesses

The purpose of this Funding Opportunity Announcement (FOA) is to support collaborative research projects designed to address adverse sequelae of cancer therapies that persist and become chronic comorbidities or develop as delayed posttreatment effects. This FOA supports basic, translational, and clinical research projects that seek to identify the mechanisms of therapy-induced adverse sequelae, clinically characterize the adverse sequelae, or translate the mechanistic understanding into therapeutic approaches to prevent or minimize the development of long-term sequelae. Research projects should focus on mechanistic studies with translational endpoints and longitudinal clinical phenotyping...


Development of Animal Models and Related Biological Materials for Research (R21 Clinical Trial Not Allowed)

Native American tribal governments (Federally recognized); For profit organizations other than small businesses; Special district governments; Public housing authorities/Indian housing authorities; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Independent school districts; Others (see text field entitled "Additional Information on Eligibility" for clarification); Private institutions of higher education; County governments; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; City or township governments; Native American tribal organizations (other than Federally recognized tribal governments); Small businesses; State governments; Public and State controlled institutions of higher education

This notice of funding opportunity (NOFO) encourages innovative research to develop, improve, characterize, and preserve animal models as well as animal model related biological materials, technologies, and new approach methodologies (NAMs) for studies relevant to human health and disease. This NOFO also seeks projects aimed at improving the diagnosis and control of diseases that could confound or interfere with animal use in biomedical research. The proposed project must have broad applicability to multiple NIH Institutes or Centers (ICs) to align with the NIH-wide mission of the Office of Research Infrastructure Programs (ORIP). The proposed studies must include animal models and explor...


Development of Biomarkers or Composite Biomarkers for Neurological and Neuromuscular Disorders (R61/R33 - Clinical Trial Optional)

Native American tribal governments (Federally recognized); Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; City or township governments; Others (see text field entitled "Additional Information on Eligibility" for clarification); Special district governments; For profit organizations other than small businesses; Small businesses; Private institutions of higher education; County governments; State governments; Independent school districts; Native American tribal organizations (other than Federally recognized tribal governments); Public housing authorities/Indian housing authorities; Public and State controlled institutions of higher education

The overarching purpose of this Funding Opportunity Announcement (FOA) is to promote the discovery and/or early evaluation of strong candidate biomarkers and biomarker signatures that can be used as tools to facilitate the clinical development of neurotherapeutics and their use in clinical practice. Specifically, the focus of this FOA is on the identification and initial biological, analytical and clinical evaluation of biomarkers and biomarker signatures for neurological and neuromuscular disorders. Although research supported by this FOA can include animal studies, it must also include preliminary human evaluation using carefully standardized human samples or datasets. The goal of this...


Dissemination and Implementation Research in Health (R01 Clinical Trial Optional)

Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Private institutions of higher education; Independent school districts; Native American tribal governments (Federally recognized); County governments; For profit organizations other than small businesses; Small businesses; Native American tribal organizations (other than Federally recognized tribal governments); Others (see text field entitled "Additional Information on Eligibility" for clarification); City or township governments; Special district governments; Public and State controlled institutions of higher education; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; State governments; Public housing authorities/Indian housing authorities

<p>The purpose of this Notice of Funding Opportunity (NOFO) is to support studies that will identify, develop, and/or test strategies for overcoming barriers to the adoption, adaptation, integration, sustainability, scale-up, and spread of evidence-based interventions, practices, programs, tools, treatments, guidelines, and policies (hereafter referred to as evidence-based interventions). Conversely, there is a benefit in understanding circumstances that create a need to stop or reduce (de-implement) the use of practices that are ineffective, unproven, low-value, or harmful. In addition, studies to advance dissemination and implementation research methods and measures are encouraged. Appl...


Dissemination and Implementation Research in Health (R03 Clinical Trial Not Allowed)

Education; Environment; Health; Income Security and Social Services

Special district governments; County governments; Private institutions of higher education; Small businesses; State governments; Native American tribal organizations (other than Federally recognized tribal governments); Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; For profit organizations other than small businesses; Independent school districts; City or township governments; Others (see text field entitled "Additional Information on Eligibility" for clarification); Public and State controlled institutions of higher education; Native American tribal governments (Federally recognized); Public housing authorities/Indian housing authorities; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education

<p>The purpose of this Funding Opportunity Announcement (FOA) is to support studies that will identify, develop, and/or test strategies for overcoming barriers to the adoption, adaptation, integration, scale-up, and sustainability of evidence-based interventions, practices, programs, tools, treatments, guidelines, and policies. Conversely, there is a benefit in understanding circumstances that create a need to stop or reduce (de-implement) the use of practices that are ineffective, unproven, low-value, or harmful. In addition, studies to advance dissemination and implementation research methods and measures are encouraged. All applications must be within the scope of the mission of one of...


Dissemination and Implementation Research in Health (R21 Clinical Trial Optional)

Native American tribal governments (Federally recognized); County governments; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Special district governments; Others (see text field entitled "Additional Information on Eligibility" for clarification); For profit organizations other than small businesses; Private institutions of higher education; State governments; Independent school districts; City or township governments; Public housing authorities/Indian housing authorities; Public and State controlled institutions of higher education; Native American tribal organizations (other than Federally recognized tribal governments); Small businesses

<p>The purpose of this Funding Opportunity Announcement (FOA) is to support studies that will identify, develop, and/or test strategies for overcoming barriers to the adoption, adaptation, integration, scale-up, and sustainability of evidence-based interventions, practices, programs, tools, treatments, guidelines, and policies. Conversely, there is a benefit in understanding circumstances that create a need to stop or reduce (de-implement) the use of practices that are ineffective, unproven, low-value, or harmful. In addition, studies to advance dissemination and implementation research methods and measures are encouraged.All applications must be within the scope of the mission of one of...


Effectiveness Trials for Post-Acute Interventions and Services to Optimize Longer-term Outcomes (R01 Clinical Trial Required)

Special district governments; For profit organizations other than small businesses; City or township governments; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Private institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification); Native American tribal governments (Federally recognized); Public housing authorities/Indian housing authorities; Native American tribal organizations (other than Federally recognized tribal governments); Small businesses; State governments; County governments; Public and State controlled institutions of higher education; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Independent school districts

NIMH seeks applications for research projects to evaluate the effectiveness of therapeutic and service delivery interventions for the post-acute management of mental health conditions affecting youth, adults, and older adults. This Notice of Funding Opportunity (NOFO) encourages clinical trials to establish the effectiveness and test hypotheses regarding moderators, mediators, and mechanisms of action of post-acute phase therapeutic and services interventions that are matched to the stage of illness in terms of both their focus (e.g., consolidating and maintaining gains from initial treatment, managing residual symptoms/impairment, preventing relapse, promoting adherence and appropriate s...


Exploratory/Developmental Bioengineering Research Grants (EBRG) (R21 Clinical Trial Not Allowed)

Public housing authorities/Indian housing authorities; Public and State controlled institutions of higher education; Private institutions of higher education; For profit organizations other than small businesses; City or township governments; Special district governments; Native American tribal organizations (other than Federally recognized tribal governments); County governments; Small businesses; State governments; Others (see text field entitled "Additional Information on Eligibility" for clarification); Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Independent school districts; Native American tribal governments (Federally recognized); Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education

Through this engineering-oriented Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) intends to encourage submissions of exploratory/developmental Bioengineering Research Grant (EBRG) applications to demonstrate feasibility and potential utility of new capabilities or improvements in quality, speed, efficacy, operability, costs, and/or accessibility of solutions to problems in basic biomedical, pre-clinical, or clinical research, clinical care delivery, or accessibility.


Exploratory/Developmental Bioengineering Research Grants (EBRG) (R21 Clinical Trial Optional)

County governments; Native American tribal organizations (other than Federally recognized tribal governments); Public housing authorities/Indian housing authorities; Independent school districts; Public and State controlled institutions of higher education; Native American tribal governments (Federally recognized); City or township governments; State governments; Private institutions of higher education; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; For profit organizations other than small businesses; Others (see text field entitled "Additional Information on Eligibility" for clarification); Small businesses; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Special district governments


Focused Technology Research and Development (R01 Clinical Trial Not Allowed)

Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; State governments; Others (see text field entitled "Additional Information on Eligibility" for clarification); Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; County governments; Independent school districts; Small businesses; Public and State controlled institutions of higher education; Native American tribal organizations (other than Federally recognized tribal governments); Native American tribal governments (Federally recognized); Public housing authorities/Indian housing authorities; City or township governments; Special district governments; Private institutions of higher education; For profit organizations other than small businesses

This Notice of Funding Opportunity (NOFO) supports projects relevant to the NIGMS mission that focus solely on the development of technologies with potential to enable acquisition of biomedical knowledge. Projects should be justified in terms of technical innovation and utility of such technical innovation for impacting future biomedical research. Outcomes or products of the proposed project should significantly advance the current state of the art and be sufficiently characterized for application in addressing a broad range of biomedical research questions.


Imaging - Science Track Award for Research Transition (I/START) (R03 Clinical Trial Optional)

County governments; Small businesses; Others (see text field entitled "Additional Information on Eligibility" for clarification); Native American tribal governments (Federally recognized); State governments; Special district governments; For profit organizations other than small businesses; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Public housing authorities/Indian housing authorities; Independent school districts; Public and State controlled institutions of higher education; Private institutions of higher education; City or township governments; Native American tribal organizations (other than Federally recognized tribal governments)

This Notice of Funding Opportunity Announcement (NOFO) is designed to encourage and facilitate the entry of investigators to the area of brain imaging research. This NOFO will support both newly independent investigators and established investigators who are seeking to develop and adopt neuroimaging tools and methodologies in their research programs and conduct small "proof-of-concept" studies relevant to substance use disorders and addiction. This NOFO is intended to support Small Research Grant (R03) projects that can be carried out in a short period of time with limited resources.


Innovative Mental Health Services Research Not Involving Clinical Trials (R01 Clinical Trials Not Allowed)

Private institutions of higher education; State governments; For profit organizations other than small businesses; City or township governments; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Public housing authorities/Indian housing authorities; Special district governments; Small businesses; Others (see text field entitled "Additional Information on Eligibility" for clarification); County governments; Public and State controlled institutions of higher education; Native American tribal organizations (other than Federally recognized tribal governments); Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Independent school districts; Native American tribal governments (Federally recognized)

The purpose of this Notice of Funding Announcement (NOFO) is to encourage innovative research that will inform and support the delivery of high-quality, continuously improving mental health services to benefit the greatest number of individuals with, or at risk for developing, a mental illness. This announcement invites applications for non-clinical trial R01-level projects that address NIMH strategic priorities for mental health services research.


Innovative Pilot Mental Health Services Research Not Involving Clinical Trials (R34 Clinical Trial Not Allowed)

Public and State controlled institutions of higher education; County governments; Independent school districts; Native American tribal governments (Federally recognized); Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; State governments; Native American tribal organizations (other than Federally recognized tribal governments); Public housing authorities/Indian housing authorities; City or township governments; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; For profit organizations other than small businesses; Private institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification); Special district governments; Small businesses

The purpose of this Notice of Funding Announcement (NOFO) is to encourage pilot research that is not an immediate precursor to testing a service intervention but is consistent with NIMH priorities for services research. While NIMH now requires use of an experimental therapeutics model for all intervention studies, there is recognition that some mission-relevant areas of services research do not involve clinical trials.


Integration of Imaging and Fluid-Based Tumor Monitoring in Cancer Therapy (R01 Clinical Trial Optional)

County governments; City or township governments; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Public housing authorities/Indian housing authorities; Native American tribal organizations (other than Federally recognized tribal governments); State governments; Special district governments; Independent school districts; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; For profit organizations other than small businesses; Small businesses; Native American tribal governments (Federally recognized); Private institutions of higher education; Public and State controlled institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification)

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) seeks research project (R01) grant applications describing projects that integrate imaging and fluid-based tumor monitoring (liquid biopsy) assays during cancer therapy in patients to determine the optimal use of those modalities in the characterization of therapy response and/or emergence of resistance.


Interventions to Address Disparities in Liver Diseases and Liver Cancer (R01 - Clinical Trials Optional)

Others (see text field entitled "Additional Information on Eligibility" for clarification); Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Public and State controlled institutions of higher education; Native American tribal organizations (other than Federally recognized tribal governments); Private institutions of higher education; City or township governments; Independent school districts; Native American tribal governments (Federally recognized); State governments; Special district governments; Small businesses; Public housing authorities/Indian housing authorities; County governments; For profit organizations other than small businesses; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education

This initiative will support multi-level and/or multi-domain intervention research to reduce disparities in liver diseases and liver cancer among populations who experience health disparities in the United States (U.S.). This NOFO is being reissued in accordance with the simplified review criteria in effect for application due dates after January 25, 2025.


Laboratories to Optimize Digital Health (R01 Clinical Trial Required)

Private institutions of higher education; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification); Public and State controlled institutions of higher education; For profit organizations other than small businesses; Special district governments; State governments; Small businesses; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Native American tribal organizations (other than Federally recognized tribal governments); Public housing authorities/Indian housing authorities; Independent school districts; County governments; Native American tribal governments (Federally recognized); City or township governments

NIMH seeks applications for innovative research projects to test strategies to increase the reach, efficiency, effectiveness, and quality of digital mental health interventions. This NOFO is intended to support the development of digital health test beds that leverage well-established digital mental health platforms,to rapidly refine and optimize existing evidence-based digital health interventions and conduct clinical trials testing digital mental health interventions that are statistically powered to provide a definitive answer regarding the intervention's effectiveness.


Limited Competition: CCRP Initiative: Promoting a Basic Understanding of Chemical Threats to Skin (R34 Clinical Trial Not Allowed)

Native American tribal organizations (other than Federally recognized tribal governments); Independent school districts; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Private institutions of higher education; County governments; City or township governments; Native American tribal governments (Federally recognized); Others (see text field entitled "Additional Information on Eligibility" for clarification); Small businesses; State governments; Special district governments; Public housing authorities/Indian housing authorities; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; For profit organizations other than small businesses; Public and State controlled institutions of higher education

This Notice of Funding Opportunity (NOFO) intends to support fundamental research that will contribute to basic understanding of skin injuries caused by chemicals that have been identified as public health threats, with an emphasis on investigating the commonalities of such injuries and identifying potential shared signaling pathways and therapeutic targets for medical countermeasure development.


Limited Competition: Small Grant Program for NIDDK K01/K08/K23/K25 Recipients (R03 Clinical Trial Optional)

Small businesses; Public and State controlled institutions of higher education; Private institutions of higher education; Native American tribal governments (Federally recognized); County governments; Special district governments; Independent school districts; Native American tribal organizations (other than Federally recognized tribal governments); Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification); Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; City or township governments; Public housing authorities/Indian housing authorities; State governments; For profit organizations other than small businesses

The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) announces a program that provides NIDDK-supported K01, K08, K23, and K25 recipients the opportunity to apply for Small Grant (R03) support at some point during the latter years of their award period of their K award. Through the use of this mechanism, the NIDDK is seeking to enhance the capability of its K01, K08, K23, and K25 award recipients to conduct research as they complete their transition to fully independent investigator status. The R03 grant mechanism supports different types of projects, including pilot and feasibility studies; secondary analysis of existing data; small, self-contained research project...


Mechanisms that Impact Cancer Risk after Bariatric Surgery (R01 Clinical Trial Optional)

Public and State controlled institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification); For profit organizations other than small businesses; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Native American tribal governments (Federally recognized); City or township governments; Native American tribal organizations (other than Federally recognized tribal governments); Public housing authorities/Indian housing authorities; Independent school districts; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; County governments; Special district governments; State governments; Private institutions of higher education; Small businesses

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) invites applications for support of investigator-initiated studies addressing mechanisms by which bariatric surgery impacts cancer risk, and seeks to draw in talented scientists who study bariatric surgery to investigate its effects on cancer, rather than shorter-term outcomes such as weight loss and diabetes.


Mechanisms that Impact Cancer Risk after Bariatric Surgery (R21 Clinical Trial Not Allowed)

Native American tribal organizations (other than Federally recognized tribal governments); Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Special district governments; Others (see text field entitled "Additional Information on Eligibility" for clarification); Public and State controlled institutions of higher education; Private institutions of higher education; Small businesses; City or township governments; Native American tribal governments (Federally recognized); Public housing authorities/Indian housing authorities; Independent school districts; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; County governments; State governments; For profit organizations other than small businesses

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) invites applications for support of investigator-initiated studies addressing mechanisms by which bariatric surgery impacts cancer risk, and seeks to draw in talented scientists who study bariatric surgery to investigate its effects on cancer, rather than shorter term outcomes such as weight loss and diabetes. The goal of this NOFO is to support proof of concept studies for feasibility and exploratory development. Feasibility must not have already been developed in the literature or with preliminary data. While unpublished data are not permitted, references and data from widely available preprints that...


Modular R01s in Cancer Control and Population Sciences (R01 Clinical Trial Optional)

Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Private institutions of higher education; Native American tribal organizations (other than Federally recognized tribal governments); Small businesses; Independent school districts; Public and State controlled institutions of higher education; Special district governments; State governments; County governments; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; For profit organizations other than small businesses; Public housing authorities/Indian housing authorities; City or township governments; Native American tribal governments (Federally recognized); Others (see text field entitled "Additional Information on Eligibility" for clarification)

This Notice of Funding Opportunity (NOFO) encourages applications for research in cancer control and population sciences. The overarching goal is to provide support to promote research efforts on novel scientific ideas that have the potential to substantially advance cancer research in statistical and analytic methods, epidemiology, cancer survivorship, cancer-related behaviors and behavioral interventions, healthcare delivery, and digital health and data science, and implementation science.


Molecular Imaging of Inflammation in Cancer (R01 Clinical Trial Not Allowed)

County governments; Private institutions of higher education; Independent school districts; Public and State controlled institutions of higher education; Native American tribal organizations (other than Federally recognized tribal governments); Public housing authorities/Indian housing authorities; For profit organizations other than small businesses; Others (see text field entitled "Additional Information on Eligibility" for clarification); City or township governments; Special district governments; Small businesses; Native American tribal governments (Federally recognized); Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; State governments; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education

The purpose of this Notice of Funding Opportunity (NOFO) is to invite research grant applications (R01) for the development and use of current and emerging molecular imaging methods to gain fundamental insights into cancer inflammation in vivo. The motivation for this initiative is that much of current imaging research into the role of inflammation in cancer is largely based on in vitro and ex vivo methods with limited utilization of imaging approaches that could lead to significant new insights relevant to dynamic cancer and inflammation interactions. Utilization of molecular imaging probes in pre-clinical and clinical investigations for precise temporal resolution at the molecular and c...


Mood and Psychosis Symptoms during the Menopause Transition (R01 Clinical Trial Optional)

Native American tribal governments (Federally recognized); County governments; Others (see text field entitled "Additional Information on Eligibility" for clarification); Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Independent school districts; Native American tribal organizations (other than Federally recognized tribal governments); Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Public housing authorities/Indian housing authorities; For profit organizations other than small businesses; Special district governments; State governments; Private institutions of higher education; City or township governments; Small businesses; Public and State controlled institutions of higher education

The purpose of this Notice of Funding Opportunity (NOFO) is to advance translational research to better understand the emergence and worsening of mood and psychotic disorders (e.g., perimenopausal depression (PMD), generalized anxiety disorder, bipolar disorder and schizophrenia) during the menopause transition (MT) in an effort to identity targets for future development of novel treatment interventions. This funding opportunity aims to advance novel and innovative translational research to better comprehend the underlying neurobiological and behavioral mechanisms of mood and psychosis disorders and related symptoms during MT. This funding opportunity also encourages interdisciplinary res...


Mood and Psychosis Symptoms during the Menopause Transition (R21 Clinical Trial Optional)

Public housing authorities/Indian housing authorities; County governments; Public and State controlled institutions of higher education; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Native American tribal governments (Federally recognized); City or township governments; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Private institutions of higher education; Native American tribal organizations (other than Federally recognized tribal governments); Independent school districts; Others (see text field entitled "Additional Information on Eligibility" for clarification); State governments; For profit organizations other than small businesses; Special district governments; Small businesses


NCMRR Early Career Research Award (R03 Clinical Trial Optional)


NEI Clinical Research Study Planning Grant Program (R34 Clinical Trial Not Allowed)

County governments; Small businesses; Independent school districts; City or township governments; Others (see text field entitled "Additional Information on Eligibility" for clarification); For profit organizations other than small businesses; Public housing authorities/Indian housing authorities; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Native American tribal organizations (other than Federally recognized tribal governments); Public and State controlled institutions of higher education; Native American tribal governments (Federally recognized); Private institutions of higher education; Special district governments; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; State governments

The NEI supports large-scale clinical vision research projects, including randomized clinical trials and epidemiologic studies on eye/vision conditions. At the time of submission, applications requesting support for these activities are expected to provide detailed information regarding the study rationale, design, analytic methods, protocols and procedures, facilities and environment, organizational structure, and collaborative arrangements. This information is best conveyed in a study protocol and Manual of Procedures (MOP), the development of which represents a costly and time-consuming activity. This clinical research planning grant funding opportunity supports applicants in their pla...


NIAID Career Transition Award (K22 Independent Clinical Trial Not Allowed)

Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Small businesses; State governments; Native American tribal governments (Federally recognized); Special district governments; Public and State controlled institutions of higher education; Native American tribal organizations (other than Federally recognized tribal governments); City or township governments; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; County governments; Public housing authorities/Indian housing authorities; For profit organizations other than small businesses; Others (see text field entitled "Additional Information on Eligibility" for clarification); Independent school districts; Private institutions of higher education

The purpose of the NIAID Career Transition Award program is to assist postdoctoral fellows' transition to positions of assistant professor or equivalent and initiate a successful biomedical career as an independent research scientist.


NICHD Small Research Grant Program (R03 Clinical Trial Required)

City or township governments; Native American tribal governments (Federally recognized); Special district governments; Public and State controlled institutions of higher education; For profit organizations other than small businesses; Small businesses; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; State governments; Public housing authorities/Indian housing authorities; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Private institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification); Independent school districts; County governments; Native American tribal organizations (other than Federally recognized tribal governments)

The NICHD Small Research Grant Program (Clinical Trial Required) supports clinical trials that fall within the NICHD mission.


Private institutions of higher education; State governments; Native American tribal organizations (other than Federally recognized tribal governments); County governments; City or township governments; For profit organizations other than small businesses; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Special district governments; Independent school districts; Others (see text field entitled "Additional Information on Eligibility" for clarification); Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Public and State controlled institutions of higher education; Small businesses; Public housing authorities/Indian housing authorities; Native American tribal governments (Federally recognized)

The purpose of the NIDCD Research Dissertation Fellowship for Au.D. Audiologists (F32) program is to support a comprehensive, rigorous biomedical research training, and dissertation research leading to a research doctorate (i.e., Ph.D.) in the biomedical, behavioral, or clinical sciences.


NIDCR Dentist Scientist Career Transition Award for Intramural Investigators (K22 Clinical Trial Not Allowed)

For profit organizations other than small businesses; City or township governments; Special district governments; Native American tribal governments (Federally recognized); Small businesses; Native American tribal organizations (other than Federally recognized tribal governments); Public and State controlled institutions of higher education; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification); Public housing authorities/Indian housing authorities; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Private institutions of higher education; County governments; Independent school districts; State governments

The purpose of the NIDCR Dentist Scientist Career Transition Award for Intramural Investigators (K22) program is to facilitate transition of highly qualified dentists from NIH Intramural postdoctoral research positions to extramural academic tenure-track or equivalent faculty positions at eligible institutions. The award will provide support for two years of mentored postdoctoral research training in the NIH Intramural Research Program, and three years of independent research funding at the extramural institution.


NIDCR Small Grant Program for New Investigators (R03 Clinical Trial Not Allowed)

State governments; Public housing authorities/Indian housing authorities; County governments; For profit organizations other than small businesses; City or township governments; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification); Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Public and State controlled institutions of higher education; Independent school districts; Native American tribal governments (Federally recognized); Special district governments; Native American tribal organizations (other than Federally recognized tribal governments); Private institutions of higher education; Small businesses

This NIDCR Small Grant Program for New Investigators supports basic and clinical research conducted by scientists who are in the early stages of establishing an independent research career in oral, dental and craniofacial research. This R03 program supports pilot or feasibility studies and developmental research projects with the intention of obtaining sufficient preliminary data for a subsequent investigator initiated Research Project Grant (R01) or equivalent application.


NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Not Allowed)


NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Required)


NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed)

Others (see text field entitled "Additional Information on Eligibility" for clarification); Public housing authorities/Indian housing authorities; Public and State controlled institutions of higher education; State governments; Private institutions of higher education; Small businesses; Native American tribal governments (Federally recognized); Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Special district governments; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; City or township governments; County governments; Independent school districts; Native American tribal organizations (other than Federally recognized tribal governments); For profit organizations other than small businesses

The NIH Research Project Grant supports a discrete, specified, circumscribed project in areas representing the specific interests and competencies of the investigator(s). The proposed project must be related to the programmatic interests of one or more of the participating NIH Institutes and Centers (ICs) based on their scientific missions. This Notice of Funding Opportunity does not accept applications proposing clinical trial(s).


NIH Research Project Grant (Parent R01 Clinical Trial Required)

Independent school districts; Public and State controlled institutions of higher education; Special district governments; Others (see text field entitled "Additional Information on Eligibility" for clarification); Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Private institutions of higher education; City or township governments; Native American tribal organizations (other than Federally recognized tribal governments); For profit organizations other than small businesses; State governments; County governments; Native American tribal governments (Federally recognized); Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Small businesses; Public housing authorities/Indian housing authorities

The NIH Research Project Grant supports a discrete, specified, circumscribed project in areas representing the specific interests and competencies of the investigator(s). This Parent Notice of Funding Opportunity Announcement requires that at lease 1 clinical trial be proposed. The proposed project must be related to the programmatic interests of one or more of the participating NIH Institutes and Centers (ICs) based on their scientific missions.


NIH Small Research Grant Program (Parent R03 Clinical Trial Not Allowed)

County governments; Small businesses; Private institutions of higher education; Special district governments; State governments; Public housing authorities/Indian housing authorities; Public and State controlled institutions of higher education; Native American tribal organizations (other than Federally recognized tribal governments); Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; For profit organizations other than small businesses; Native American tribal governments (Federally recognized); Independent school districts; City or township governments; Others (see text field entitled "Additional Information on Eligibility" for clarification); Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education

The NIH Small Research Grant Program supports small research projects that can be carried out in a short period of time with limited resources. This program supports different types of projects including pilot and feasibility studies; secondary analysis of existing data; small, self-contained research projects; development of research methodology; and development of new research technology. This Notice of Funding Opportunity does not accept applications proposing clinical trial(s).