Addressing Methodological Challenges with Clinical Trials of Rapid-Acting Psychotropic Interventional Drugs (RAPIDs) (R01 Clinical Trial Required)


Innovative Programs to Enhance Research Training (IPERT) (R25 Independent Clinical Trial Not Allowed)

State governments; County governments; City or township governments; Public housing authorities/Indian housing authorities; Special district governments; Public and State controlled institutions of higher education; Native American tribal governments (Federally recognized); Others (see text field entitled "Additional Information on Eligibility" for clarification); Independent school districts; Private institutions of higher education; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Small businesses; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Native American tribal organizations (other than Federally recognized tribal governments); For profit organizations other than small businesses

NIGMS will support innovative educational activities designed to equip participants with technical, operational, or professional skills required for careers in the biomedical research workforce. Activities must be open to the broader biomedical research community and may focus on participants at one or more career stages from undergraduates to professionals (for example faculty, staff scientists). Funded programs will have a robust program leadership structure, participant recruitment plan, and evaluation and dissemination plans.

Official Grants.gov search and detail API row; no applicant-fit screening was applied.


Mathematical Biology

Included from broad Grants.gov search; detail not fetched yet.


NCI Pathway to Independence Award for Early-Stage Postdoctoral Researchers (K99/R00 - Independent Clinical Trial Not Allowed)


NCI Pathway to Independence Award for Early-Stage Postdoctoral Researchers (K99/R00 - Independent Clinical Trial Required)

City or township governments; Public housing authorities/Indian housing authorities; Independent school districts; Native American tribal governments (Federally recognized); Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Special district governments; Private institutions of higher education; County governments; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification); Public and State controlled institutions of higher education; Small businesses; State governments; For profit organizations other than small businesses; Native American tribal organizations (other than Federally recognized tribal governments)

The purpose of the NCI Pathway to Independence Award for Early-Stage Postdoctoral Researchers (K99/R00) program is to increase and maintain a strong cohort of new and talented, NCI-supported, independent investigators. This program is designed for postdoctoral fellows with research and/or clinical doctoral degrees who do not require an extended period of mentored research training beyond their doctoral degrees. The objective of this award is to facilitate a timely transition of these fellows from their mentored, postdoctoral research positions to independent tenure-track (or equivalent) faculty positions. The program will provide independent NCI research support during this transition to...

Award size not listed in Grants.gov synopsis; verify NOFO


Research Experiences for Teachers (RET) in Engineering and Computer Science


Revision Applications for Validation of Biomarker Assays Developed Through NIH-Supported Research Grants (R01 Clinical Trial Not Allowed)


NSF Astronomy and Astrophysics Postdoctoral Fellowships


CCRP Initiative: NIH Countermeasures Against Chemical Threats (CounterACT) Basic Research on Chemical Threats that Affect the Nervous System (R01 Clinical Trial Not Allowed)


Specialty Crop Multi-State Grant Program 2026


Limited Competition: Small Grant Program for the NCATS Clinical and Translational Science Award (CTSA) Program (R03 Clinical Trial Optional)

Native American tribal organizations (other than Federally recognized tribal governments); Public and State controlled institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification); Native American tribal governments (Federally recognized); County governments; Independent school districts; Public housing authorities/Indian housing authorities; State governments; Special district governments; For profit organizations other than small businesses; Small businesses; City or township governments; Private institutions of higher education; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education

<p>The purpose of this NOFO is to enhance the capability of NCATS CTSA Program KL2 scholars and recipients of re-entry supplements supported by the CTSA Program to conduct research as they complete the transition to fully independent academic translational scientists. These R03 grants will support different clinical and translational science research projects, including pilot and feasibility studies; secondary data analysis of existing data; small, self-contained research projects; development of research methodology; and development of new research technology. Research proposed in the R03 application may or may not include patient-oriented research. The R03 is, therefore, intended to sup...


Historically Black Colleges and Universities - Excellence in Research


Mathematical Sciences Postdoctoral Research Fellowships


DoW Arthritis Clinical Research Award


DoW Arthritis Translational Research Award


DoW Tick-Borne Disease Idea Development Award


DoW Tick-Borne Disease Therapeutic/Diagnostic Research Award


Population Assessment of Tobacco and Health (PATH) Study Biospecimen Access (X01)


RESTORE Act Centers of Excellence Research Grants Program

U.S. Dept. of Treasury RESTORE Act Program


RESTORE Act Direct Component – Construction and Real Property Acquisition Activities


RESTORE Act Direct Component - Non-Construction Activities


County governments; Special district governments; Native American tribal organizations (other than Federally recognized tribal governments); Public and State controlled institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification); Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Native American tribal governments (Federally recognized); Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Private institutions of higher education; Public housing authorities/Indian housing authorities; City or township governments; Small businesses; State governments; Independent school districts; For profit organizations other than small businesses

This Clinical Observational (CO) Studies in Musculoskeletal, Rheumatic, and Skin Diseases (R01 Clinical Trial Not Allowed) PAR, was re-issued as a result of the Simplifying Review of Research Project Grant Applications [link: https://grants.nih.gov/policy-and-compliance/policy-topics/peer-review/simplifying-review]. The Simplified Review changes in Section V are the only changes that have been made. All other aspects of this funding opportunity remain the same.


Special district governments; Small businesses; City or township governments; Native American tribal governments (Federally recognized); County governments; Public and State controlled institutions of higher education; Public housing authorities/Indian housing authorities; Native American tribal organizations (other than Federally recognized tribal governments); For profit organizations other than small businesses; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; State governments; Private institutions of higher education; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Independent school districts; Others (see text field entitled "Additional Information on Eligibility" for clarification)

This Exploratory Clinical Trial Grants in Arthritis and Musculoskeletal and Skin Diseases (R61 Clinical Trial Required) PAR, a re-issue of PAR-24-035, was re-issued as a result of the Simplifying Review of Research Project Grant Applications [link: https://grants.nih.gov/policy-and-compliance/policy-topics/peer-review/simplifying-review]. The Simplify Review changes in Section V are the only changes that have been made. All other aspects of this funding opportunity remain the same.


Geometric Analysis


Topology


SBE Postdoctoral Research Fellowships


Developing novel theory and methods for understanding the genetic architecture of complex human traits (R01 Clinical Trial Not Allowed)

Native American tribal organizations (other than Federally recognized tribal governments); Public and State controlled institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification); City or township governments; For profit organizations other than small businesses; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Small businesses; Native American tribal governments (Federally recognized); Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Special district governments; County governments; Public housing authorities/Indian housing authorities; State governments; Independent school districts; Private institutions of higher education

The goal of this NOFO is to support applications for novel theory and methods development that enable better understanding of how genetic and non-genetic factors contribute to complex trait variation across individuals, families, and populations. Approaches should be interdisciplinary drawing from the natural and social sciences, account for interdependencies across scales of biological, social, and ecological organization, and make extensive use of theory, modeling, and validation with available large-scale datasets.


DoW Spinal Cord Injury, Clinical Translation Research Award


DoW Spinal Cord Injury, Clinical Trial Award


DoW Spinal Cord Injury, Investigator-Initiated Research Award


DoW Spinal Cord Injury, Translational Research Award


DoW Vision, Clinical Trial Award


DoW Vision, Investigator-Initiated Research Award


DoW Vision, Translational Research Award


NCCIH Natural Product Early Phase Clinical Trial Award (R33 Clinical Trial Required)


NCCIH Natural Product Early Phase Clinical Trial Phased Innovation Award (R61/R33 Clinical Trial Required)


NCCIH Natural Product Mid Phase Clinical Trial (R01 Clinical Trial Required)

County governments; Native American tribal governments (Federally recognized); Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Native American tribal organizations (other than Federally recognized tribal governments); City or township governments; Others (see text field entitled "Additional Information on Eligibility" for clarification); Public and State controlled institutions of higher education; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; State governments; Private institutions of higher education; Independent school districts; Special district governments; For profit organizations other than small businesses; Public housing authorities/Indian housing authorities; Small businesses

This Notice of Funding Opportunity (NOFO) encourages applications for investigator-initiated mid-phase clinical trials of natural products(i.e., botanicals, dietary supplements, and probiotics), which have a strong scientific premise to justify further clinical testing. For this NOFO, natural products include promising nutritional regimens that standardize the amount of a specific naturally occurring nutritional compound (e.g., omega-3 fatty acids, anthocyanidins, or polyphenols) and have compelling preliminary evidence. All applications submitted under this NOFO must be supported by sufficient preliminary data demonstrating bioavailability (if applicable) and documentation that the natur...

Program funding about $350,000; award size verify NOFO


NIDA Mentored Clinical Scientist Development Program Award in Substance Use and Substance Use Disorder Research (K12 Clinical Trial Optional)


Advanced Technologies and Instrumentation for the Astronomical Sciences


Applied Mathematics


Astronomy and Astrophysics Research Grants


Ethical, Legal and Social Implications (ELSI) Small Research Grant (R03 Clinical Trial Optional)

Education; Environment; Health; Income Security and Social Services

Public housing authorities/Indian housing authorities; Small businesses; Private institutions of higher education; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; County governments; Special district governments; Independent school districts; Public and State controlled institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification); Native American tribal organizations (other than Federally recognized tribal governments); For profit organizations other than small businesses; Native American tribal governments (Federally recognized); State governments; City or township governments; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education

<p>The purpose of this Notice of Funding Opportunity (NOFO) is to invite Small Research Grant (R21) applications that propose to study the ethical, legal, and social implications (ELSI) of human genetics and genomics. Applications may propose studies using either single or mixed methods. Direct involvement of key stakeholders where appropriate is encouraged. These applications should be for small research projects, such as those that involve single investigators. Of particular interest are projects that propose normative or conceptual analyses, including focused legal, economic, philosophical, anthropological, or historical analyses of new or emerging issues. This mechanism can also be us...


Major Research Instrumentation Program


Plasma Physics


Feasibility Clinical Trials of Mind and Body Interventions for NCCIH High Priority Research Topics (R34 Clinical Trial Required)

Public and State controlled institutions of higher education; Public housing authorities/Indian housing authorities; County governments; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; For profit organizations other than small businesses; Independent school districts; Native American tribal governments (Federally recognized); Native American tribal organizations (other than Federally recognized tribal governments); City or township governments; Private institutions of higher education; Special district governments; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification); Small businesses; State governments

<p>The goal of this notice of funding opportunity (NOFO) is to support feasibility trials of complementary and integrative health approaches with physical and/or psychological therapeutic inputs (often called mind and body interventions) for conditions that have been identified by NCCIH as high-priority research topics. This funding opportunity is intended to support feasibility clinical trials that provide new information that are scientifically necessary for the planning and conduct of a subsequent clinical efficacy or effectiveness study, pragmatic trial, or dissemination and implementation trial within NCCIHs mission. NCCIH expects that applications to this NOFO will describe the plan...


Investigator Initiated Clinical Trials of Complementary and Integrative Interventions Delivered Remotely or via mHealth (R01 Clinical Trial Required)

Native American tribal governments (Federally recognized); For profit organizations other than small businesses; Special district governments; City or township governments; Private institutions of higher education; County governments; Others (see text field entitled "Additional Information on Eligibility" for clarification); Public housing authorities/Indian housing authorities; State governments; Independent school districts; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Public and State controlled institutions of higher education; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Small businesses; Native American tribal organizations (other than Federally recognized tribal governments)

<p>This Notice of Funding Opportunity (NOFO) encourages applications for investigator-initiated fully remotely delivered and conducted clinical trials to assess the efficacy or effectiveness of complementary and integrative health interventions in NCCIH- designated areas of high research priority. Applications submitted under this NOFO are expected to propose a remotely delivered and conducted fully powered clinical trial with no in-person contact between research staff and study participants and may utilize mHealth tools or technologies. Applicants must provide justification for the remotely delivered approach and provide preliminary data on the feasibility and safety of the approach, al...


NCCIH Multi-Site Feasibility Clinical Trials of Mind and Body Interventions (R01 Clinical Trial Required)

Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Small businesses; State governments; Independent school districts; Others (see text field entitled "Additional Information on Eligibility" for clarification); Private institutions of higher education; Native American tribal organizations (other than Federally recognized tribal governments); County governments; Public and State controlled institutions of higher education; For profit organizations other than small businesses; Special district governments; Public housing authorities/Indian housing authorities; City or township governments; Native American tribal governments (Federally recognized)

This notice of funding opportunity (NOFO) invites applications for investigator-initiated clinical trials of complementary and integrative health approaches with physical and/or psychological therapeutic inputs (often called mind and body interventions) in NCCIH-designated areas of high research priority. Applications submitted under this NOFO are expected to propose a multisite feasibility clinical trial that will provide new information that is scientifically necessary for the planning and conduct of a subsequent clinical efficacy or effectiveness study, pragmatic trial, or dissemination and implementation trial within NCCIHs mission. NCCIH expects that applications to this NOFO will de...


Prevention and Intervention Approaches for Fetal Alcohol Spectrum Disorders (R61/R33 Clinical Trial Optional)


Ethical, Legal and Social Implications (ELSI) Exploratory/Developmental Research Grant (R21 Clinical Trial Optional)

Native American tribal organizations (other than Federally recognized tribal governments); Independent school districts; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Special district governments; Public and State controlled institutions of higher education; City or township governments; Native American tribal governments (Federally recognized); State governments; Private institutions of higher education; County governments; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Small businesses; Public housing authorities/Indian housing authorities; Others (see text field entitled "Additional Information on Eligibility" for clarification); For profit organizations other than small businesses

The purpose of this NOFO is to invite Exploratory/Developmental Research Grant (R21) applications that propose to study the ethical, legal, and social implications (ELSI) of human genetics and genomics. Applications may propose studies using either single or mixed methods. Approaches may include but are not limited to empirical qualitative and quantitative methods, as well as conceptual, legal, and normative analyses. Direct involvement of key stakeholders where appropriate is encouraged. Of particular interest are studies that explore the implications of new or emerging genomic technologies or novel uses of genomic information.


Ethical, Legal and Social Implications (ELSI) Research (R01 Clinical Trial Optional)

Special district governments; State governments; Native American tribal governments (Federally recognized); Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification); City or township governments; Independent school districts; Public housing authorities/Indian housing authorities; Small businesses; Private institutions of higher education; For profit organizations other than small businesses; Native American tribal organizations (other than Federally recognized tribal governments); Public and State controlled institutions of higher education; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; County governments

The purpose of this NOFO is to invite Research Project (R01) applications that propose to study the ethical, legal, and social implications (ELSI) of human genetics and genomics. Applications may propose studies using either single or mixed methods. Approaches may include but are not limited to empirical qualitative and quantitative methods, as well as conceptual, legal, and normative analyses. Direct involvement of key stakeholders where appropriate is encouraged. This Notice of Funding Opportunity (NOFO) requires a Plan for Enhancing Diverse Perspectives (PEDP) as part of the application. Applications without a PEDP will not be reviewed.


Louis Stokes Alliances for Minority Participation


HEAL Initiative: Pain Research Enhancement Program (PREP) (R15 Clinical Trial Optional)

Health; Income Security and Social Services

Others (see text field entitled "Additional Information on Eligibility" for clarification); Public and State controlled institutions of higher education; Private institutions of higher education

The purpose of this initiative is to: (1) support the efforts by R15-eligible Principal Investigators (PIs) to conduct rigorous basic and/or mechanistic pain research projects; (2) promote integrated, interdisciplinary research partnerships between R15-eligible PIs and additional investigators from U.S. domestic institutions, and (3) enhance the pain research environment at the R15-eligible institution for health professional trainees or undergraduate and/or graduate students by actively engaging them in the proposed pain research projects.


Competing Revisions to Existing NIH Single Project Research Grants and Cooperative Agreements (Clinical Trial Optional)


Information Innovation Office (I2O) Office-Wide


Archaeometry


Computational Mathematics


Emerging Global Leader Award (K43 Independent Clinical Trial Not Allowed)


Emerging Global Leader Award (K43 Independent Clinical Trial Required)

Others (see text field entitled "Additional Information on Eligibility" for clarification)

This is a reissue of the Emerging Global Leader Program (K43) to align with the clinical trials policy.


Centers of Research Excellence in Science and Technology


NIH Research Software Engineer (RSE) Award (R50 Clinical Trials Not Allowed)

Education; Environment; Food and Nutrition; Health; Income Security and Social Services

Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Small businesses; Native American tribal governments (Federally recognized); Native American tribal organizations (other than Federally recognized tribal governments); Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Public housing authorities/Indian housing authorities; Independent school districts; County governments; Private institutions of higher education; Public and State controlled institutions of higher education; For profit organizations other than small businesses; State governments; Special district governments; Others (see text field entitled "Additional Information on Eligibility" for clarification); City or township governments

The purpose of this notice of funding opportunity (NOFO) is to provide salary support for exceptional Research Software Engineers (RSEs) that contribute their skills to the development and dissemination of biomedical, behavioral or health related software, tools, and algorithms as well as to the training of prospective users of these tools.


Boosting Innovative GEOINT - Science & Technology Broad Agency Announcement (BIG-ST BAA)


Statistics


TTO Office Wide (OW) BAA 2025


Fiscal Year 2024 Flood Mitigation Assistance Swift Current


Agriculture and Food Research Initiative Competitive Grants Program Education and Workforce Development

National Institute of Food and Agriculture


Agriculture and Food Research Initiative Competitive Grants Program Foundational and Applied Science Program


F26AS00084 Aquatic Invasive Species Grants to Great Lakes Tribes - Fiscal Year 2026 Great Lakes Restoration Initiative


Measurement Science and Engineering (MSE) Research Grant Programs

Science and Technology and other Research and Development

To support activities that develop, expand, strengthen, or sustain NIST partnership programs and/or support the conduct of research or a recipient's portion of collaborative research in a variety of areas including, but not limited to: Metrology; Standards; Nanotechnology; Artificial Intelligence; Advanced Communications; Advanced Manufacturing; <span style="color: window...


Tribal Colleges Research Grants Program


Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions (R15 Clinical Trial Required)


Academic-Industrial Partnerships (AIP) to Translate and Validate In Vivo Imaging Systems (R01 Clinical Trial Optional)


Accelerating Solutions to Improve Access and Quality of Empirically-Supported Practices for Youth Mental Health (R01 Clinical Trial Optional)

Special district governments; For profit organizations other than small businesses; Public and State controlled institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification); State governments; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; County governments; Public housing authorities/Indian housing authorities; Private institutions of higher education; Independent school districts; Small businesses; Native American tribal governments (Federally recognized); Native American tribal organizations (other than Federally recognized tribal governments); Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; City or township governments

This NOFO is a call to action in response to the mental health crisis in the United States. We seek applications that will study methods to increase access to evidence-based interventions and services for youth mental health, including those living in rural areas, inner cities, and other under-resourced areas, and youth experiencing housing and food insecurities and out-right homelessness. Applications should address research related to optimizing assessment, intervention and service strategies, overcoming challenges related to the workforce shortage, wait lists for treatment, integration of treatment and preventive interventions into settings where people are most likely to be best ident...


Cancer Prevention and Control Clinical Trials Grant Program (R01 Clinical Trial Required)

Public housing authorities/Indian housing authorities; County governments; Native American tribal organizations (other than Federally recognized tribal governments); State governments; For profit organizations other than small businesses; City or township governments; Special district governments; Private institutions of higher education; Native American tribal governments (Federally recognized); Public and State controlled institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification); Small businesses; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Independent school districts; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education

Through this notice of funding opportunity (NOFO), the National Cancer Institute (NCI) invites applications for support of investigator-initiated clinical trials that have the potential to reduce the burden of cancer through improvements in early detection, screening, prevention and interception, healthcare delivery, quality of life, and/or survivorship related to cancer; with such attributes, the proposed studies should also have the potential to improve clinical practice and/or public health. Applications submitted to this NOFO must include studies that meet the National Institutes of Health (NIH) definition of a clinical trial (see NOT-OD-15-015 for details) and provide specific clinic...


Cancer Research Education Grants Program - Courses for Skills Development (R25 Clinical Trial Not Allowed)

Others (see text field entitled "Additional Information on Eligibility" for clarification); Independent school districts; Native American tribal governments (Federally recognized); County governments; Native American tribal organizations (other than Federally recognized tribal governments); Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Special district governments; For profit organizations other than small businesses; Small businesses; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Public and State controlled institutions of higher education; City or township governments; Private institutions of higher education; State governments; Public housing authorities/Indian housing authorities

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The over-arching goal of this NCI R25 program is to support educational activities that complement and/or enhance the training of a workforce to meet the nations biomedical, behavioral and clinical research needs. To accomplish the stated over-arching goal, this Notice of Funding Opportunity (NOFO) will support creative educational activities with a primary focus on Courses for Skills Development. Applications are encouraged that propose innovative, state-of-the-art programs that address the cause, diagnosis, prevention, or treatment of cancer, rehabilitation from cancer, or th...


Cancer Research Education Grants Program - Curriculum or Methods Development (R25 Clinical Trial Not Allowed)


Cancer Research Education Grants Program - Research Experiences (R25 Clinical Trial Not Allowed)

Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Native American tribal governments (Federally recognized); Public housing authorities/Indian housing authorities; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Private institutions of higher education; For profit organizations other than small businesses; Public and State controlled institutions of higher education; Special district governments; Native American tribal organizations (other than Federally recognized tribal governments); County governments; Independent school districts; Others (see text field entitled "Additional Information on Eligibility" for clarification); State governments; Small businesses; City or township governments

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The over-arching goal of this NCI R25 program is to support educational activities that complement and/or enhance the training of a workforce to meet the nations biomedical, behavioral and clinical research needs. To accomplish the stated over-arching goal, this Notice of Funding Opportunity (NOFO) will support creative educational activities with a primary focus on Research Experiences. Applications are encouraged that propose innovative, state-of-the-art programs that address the cause, diagnosis, prevention, or treatment of cancer, rehabilitation from cancer, or the continui...


Developing novel theory and methods for understanding the genetic architecture of complex human traits (R21 Clinical Trial Not Allowed)

Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Native American tribal organizations (other than Federally recognized tribal governments); For profit organizations other than small businesses; Public and State controlled institutions of higher education; Independent school districts; State governments; Native American tribal governments (Federally recognized); Private institutions of higher education; County governments; Special district governments; Small businesses; Others (see text field entitled "Additional Information on Eligibility" for clarification); Public housing authorities/Indian housing authorities; City or township governments; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education

The goal of this NOFO is to support R21 applications for novel theory and methods development that better delineate how genetic and non-genetic factors contribute to complex trait variation across individuals, families, and populations. Approaches should be interdisciplinary across the natural and social sciences, account for interdependencies across scales of biological, social, and ecological organization, and make extensive use of theory, simulations, and validation using available large-scale datasets


Intervention Research to Improve Native American Health (R01 Clinical Trial Optional)

County governments; Independent school districts; Public housing authorities/Indian housing authorities; For profit organizations other than small businesses; City or township governments; Private institutions of higher education; Native American tribal governments (Federally recognized); State governments; Special district governments; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Public and State controlled institutions of higher education; Small businesses; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification); Native American tribal organizations (other than Federally recognized tribal governments)

Not available


Intervention Research to Improve Native American Health (R34 Clinical Trial Optional)

Independent school districts; Special district governments; Others (see text field entitled "Additional Information on Eligibility" for clarification); Small businesses; State governments; County governments; City or township governments; For profit organizations other than small businesses; Public and State controlled institutions of higher education; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Public housing authorities/Indian housing authorities; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Private institutions of higher education; Native American tribal organizations (other than Federally recognized tribal governments); Native American tribal governments (Federally recognized)

<p>The purpose of this notice of funding opportunity (NOFO) is to support research on interventions to improve health in Native American (NA) populations. This includes 1) etiologic research, where there is a significant gap in knowledge, that will directly inform intervention development or adaptations, 2) research that develops, adapts, or tests the efficacy or effectiveness of health promotion and disease prevention interventions, 3) research that tests culturally informed treatment or recovery interventions and 4) where a sufficient body of knowledge on intervention efficacy exists, research on dissemination and implementation that develops and tests strategies to overcome barriers to...


Interventions to expand cancer screening and preventive services to ADVANCE health in populations that experience health disparities (R01, Clinical Trial Required)

Public housing authorities/Indian housing authorities; Small businesses; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; For profit organizations other than small businesses; City or township governments; Independent school districts; County governments; Private institutions of higher education; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Native American tribal organizations (other than Federally recognized tribal governments); Others (see text field entitled "Additional Information on Eligibility" for clarification); Special district governments; State governments; Native American tribal governments (Federally recognized); Public and State controlled institutions of higher education

The Office of Disease Prevention (ODP) and participating National Institutes of Health (NIH) Institutes, Centers, and Offices (ICs) are issuing this R01 to solicit applications to address barriers and facilitators that impede use or uptake of cancer screening and preventive services in populations that experience health disparities.

Interventions should include screening, preventive services, or other healthcare processes, including timely follow-up of abnormal findings, and referral to accessible care. Projects are encouraged to leverage collaborations with community partners and service providers. Interventions should address barriers and facilitators at two or more of th...


Mechanisms that Impact Cancer Risk with Use of Incretin Mimetics (R01 Clinical Trial Optional)

Independent school districts; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Native American tribal organizations (other than Federally recognized tribal governments); Public and State controlled institutions of higher education; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Native American tribal governments (Federally recognized); Small businesses; Public housing authorities/Indian housing authorities; City or township governments; Special district governments; County governments; Private institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification); State governments; For profit organizations other than small businesses

The goal of the proposed funding announcement is twofold, to promote preclinical and patient based studies examining the mechanism(s) through which incretin mimetics (including agonists or antagonists of GLP-1, GIP-1, or dual GLP-1/GIP-1 agents) impact cancer risk, and to draw talented scientists who understand the dynamic changes caused by these agents to investigate the mechanisms of how these agents influence cancer risk rather than shorter term outcomes such as weight loss and diabetes. The data thus far suggests that these agents may increase the risk of some, while decreasing the risk of other obesity related cancers.


Mechanisms that Impact Cancer Risk with Use of Incretin Mimetics (R21 Clinical Trial Not Allowed)

County governments; Independent school districts; For profit organizations other than small businesses; Special district governments; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Native American tribal governments (Federally recognized); Public housing authorities/Indian housing authorities; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Public and State controlled institutions of higher education; Small businesses; Others (see text field entitled "Additional Information on Eligibility" for clarification); Private institutions of higher education; State governments; City or township governments; Native American tribal organizations (other than Federally recognized tribal governments)


NHLBI Clinical Trial Pilot Studies (R34 Clinical Trial Optional)

State governments; Native American tribal governments (Federally recognized); Native American tribal organizations (other than Federally recognized tribal governments); Special district governments; For profit organizations other than small businesses; Public and State controlled institutions of higher education; Private institutions of higher education; County governments; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Small businesses; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification); Public housing authorities/Indian housing authorities; Independent school districts; City or township governments

This Notice of Funding Opportunity Announcement (NOFO) intends to supports studies that are both necessary and sufficient to inform the planning of a Phase II-IV clinical trial within NHLBI's mission. The NHLBI expects that applications to this NOFO will describe the planned clinical trial and in so doing demonstrate that the proposed (R34) research is scientifically necessary to design or plan the subsequent trial. Furthermore, this NOFO will support research projects that are designed to provide results that will be sufficient to inform the future trial without further studies. The planned Phase II, III, or IV trial must be primarily intended to test the efficacy, safety, clinical manag...


NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics for HLBS Disorders (R33 CT Required)

Public and State controlled institutions of higher education; Private institutions of higher education; Native American tribal governments (Federally recognized); Special district governments; State governments; City or township governments; County governments; Small businesses; Public housing authorities/Indian housing authorities; Independent school districts; For profit organizations other than small businesses; Native American tribal organizations (other than Federally recognized tribal governments); Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification)

The objective of this funding opportunity is to support investigator-initiated, phase I clinical trials for diagnostic and therapeutic interventions for heart, lung, blood, and sleep (HLBS) disorders in adults and children. The proposed trial can be single or multisite. Applicants applying for funding under this NOFO should be ready to initiate the clinical trial within the first quarter of the project period. Discussion, submission, and attainment of applicable regulatory (FDA, DSMB, IRB) approvals, and establishment of drug (and placebo, if applicable) supplies, and any necessary third-party agreements should be established by the time of award. If time and support for these and other p...


NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics for HLBS Disorders (R61/R33 Clinical Trial Required)

For profit organizations other than small businesses; State governments; Special district governments; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; County governments; Public and State controlled institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification); Independent school districts; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; City or township governments; Native American tribal governments (Federally recognized); Small businesses; Native American tribal organizations (other than Federally recognized tribal governments); Private institutions of higher education; Public housing authorities/Indian housing authorities

The objective of this funding opportunity is to support investigator-initiated, Phase I clinical trials for diagnostic and therapeutic interventions for heart, lung, blood, and sleep (HLBS) disorders in adults and children. In addition to supporting clinical trial start-up and implementation activities, this FOA will provide support for final stage preclinical activities needed for the implementation of the proposed trial. All the activities proposed in the R61 phase must be directly related to the therapeutic/diagnostic in preparation for the clinical trial. The proposed trial can be single or multisite. This NOFO will utilize a bi-phasic, milestone-driven mechanism of award where the fi...


National Cancer Institute's Investigator-Initiated Early Phase Clinical Trials for Cancer Treatment and Diagnosis (R01 Clinical Trial Required)

Public and State controlled institutions of higher education; County governments; Native American tribal governments (Federally recognized); Independent school districts; Native American tribal organizations (other than Federally recognized tribal governments); State governments; Special district governments; For profit organizations other than small businesses; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Private institutions of higher education; Public housing authorities/Indian housing authorities; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; City or township governments; Small businesses; Others (see text field entitled "Additional Information on Eligibility" for clarification)

Through this Notice of Funding Opportunity, the National Cancer Institute (NCI) seeks research projects that implement early phase (Phase 0, I, and II) investigator-initiated clinical trials focused on cancer-targeted diagnostic and therapeutic interventions of direct relevance to the research mission of DCTD and OHAM. The proposed project must involve at least 1 clinical trial related to the scientific interests of one or more of the following research programs: Cancer Therapy Evaluation Program, Cancer Imaging Program, Cancer Diagnosis Program, Radiation Research Program, Complementary and Alternative Medicine Program and/or the HIV and AIDS Malignancies Research Programs. Applicants ma...


Personal Health Informatics for Delivering Actionable Insights to Individuals (R01 Clinical Trial Optional)


Population Approaches to Reducing Alcohol-related Cancer Risk (R01 Clinical Trial Optional)

County governments; Independent school districts; City or township governments; Public housing authorities/Indian housing authorities; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Special district governments; Small businesses; Private institutions of higher education; Native American tribal governments (Federally recognized); Public and State controlled institutions of higher education; State governments; Native American tribal organizations (other than Federally recognized tribal governments); For profit organizations other than small businesses; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification)

This Notice of Funding Opportunity (NOFO) aims to support research on interdisciplinary population approaches to increasing awareness of the relationship between alcohol and cancer risk, understanding and changing social norms related to alcohol consumption, developing and/or evaluating alcohol policy approaches, and the development, testing, and implementation of population-level interventions to reduce alcohol-related cancer risk. Applications that address multiple levels of consumption, such as moderate and heavy drinking, are of particular interest, as well as those focusing on alcohol use disorder (AUD) from the perspective of cancer prevention and control.


Prevention and Intervention Approaches for Fetal Alcohol Spectrum Disorders (R34 Clinical Trial Optional)

Public housing authorities/Indian housing authorities; Special district governments; Public and State controlled institutions of higher education; County governments; Small businesses; State governments; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Native American tribal governments (Federally recognized); Private institutions of higher education; For profit organizations other than small businesses; Native American tribal organizations (other than Federally recognized tribal governments); Independent school districts; City or township governments; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification)

This Notice of Funding Opportunity (NOFO) for R34 planning grant applications focuses on prevention and intervention strategies for fetal alcohol spectrum disorders (FASD) throughout the lifespan. The intent of this NOFO is to support research that advances (1) prevention approaches to reduce prenatal alcohol exposure and incidence of FASD and (2) interventions for FASD. It is expected that research conducted via this mechanism will consist of studies that are a pre-requisite for preparing and submitting subsequent applications for larger scale FASD prevention or intervention studies. Applicants interested in exploratory phased projects may consider NOFO (TEMP-23833, the R61/R33 option).


Unveiling Health and Healthcare Disparities in Non-Communicable and Chronic Diseases in Latin America: Setting the Stage for Better Health Outcomes Across the Hemisphere (R01 - Clinical Trials Not Allowed)

Public and State controlled institutions of higher education; County governments; Private institutions of higher education; Public housing authorities/Indian housing authorities; Native American tribal organizations (other than Federally recognized tribal governments); Others (see text field entitled "Additional Information on Eligibility" for clarification); Independent school districts; Small businesses; For profit organizations other than small businesses; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; City or township governments; Native American tribal governments (Federally recognized); State governments; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Special district governments

This Notice of Funding Opportunity (NOFO) will support innovative, collaborative, and multi-disciplinary research focused on clinical epidemiology, evaluation of public and/or health care policies, and validation of measurements that address health and health care disparities related to non-communicable and chronic diseases (NCDs) with the highest disease burden and mortality in Latin America and among U.S. Hispanics/Latinos. Multi-disciplinary research teams would be expected to meaningfully collaborate with key partners that must include at least one PI or MPI from institutions in Latin America.


Title X Family Planning Services Grants

Office of the Assistant Secretary for Health


Oceanographic Facilities and Equipment Support


HEAL Initiative: Studies to Enable Analgesic Discovery (R61/R33 - Clinical Trial Not Allowed)

Education; Food and Nutrition; Health; Income Security and Social Services

Native American tribal governments (Federally recognized); Native American tribal organizations (other than Federally recognized tribal governments); City or township governments; Others (see text field entitled "Additional Information on Eligibility" for clarification); Small businesses; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; For profit organizations other than small businesses; State governments; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Special district governments; Public and State controlled institutions of higher education; Public housing authorities/Indian housing authorities; Private institutions of higher education; Independent school districts; County governments

This funding opportunity is part of a suite of NOFOs within the NIH HEAL Initiative to support the development of safe, effective, and non-addictive therapeutics to treat pain. The goal is to encourage initial translational efforts that will support a drug discovery program and advance projects to the point where they meet the entry criteria for the Pain Therapeutics Development Program. The scope will therefore be focused on development of assays to support a distinct testing funnel, screening efforts to identify hits, and initial characterization of hits and potential therapeutic agents (including small molecules, biologics, and natural products).


Cybersecurity Innovation for Cyberinfrastructure


Training-based Workforce Development for Advanced Cyberinfrastructure (CyberTraining)


Medical Scientist Training Program (MSTP) (T32)


ROSS Rapid Response Program

Department of Housing and Urban Development


EPSCoR Research Infrastructure Improvement Program: Focused EPSCoR Collaborations Program (FEC)


National Centers for Cryo-electron Tomography (cryoET) (R24 -Clinical Trial Not Allowed)


Diabetes Research Centers (P30 Clinical Trial Optional)


Tribal Institutional Review Board Establishment and Enhancement (TIRBEE) (R24 - Clinical Trial Not Allowed)


BRAIN Initiative: Preclinical Proof of Concept for Novel Recording and Modulation Technologies in the Human CNS (R18 - Clinical Trial Not Allowed)


Translational Neural Devices (R61/R33 - Clinical Trial Optional)

Native American tribal governments (Federally recognized); Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; For profit organizations other than small businesses; Native American tribal organizations (other than Federally recognized tribal governments); Public and State controlled institutions of higher education; Small businesses; City or township governments; Special district governments; Independent school districts; Others (see text field entitled "Additional Information on Eligibility" for clarification); Public housing authorities/Indian housing authorities; Private institutions of higher education; State governments; County governments

The purpose of this Notice of Funding Opportunity (NOFO) is to encourage investigators to pursue translational activities and small clinical studies to advance the development of therapeutic, and diagnostic devices for disorders that affect the nervous or neuromuscular systems. Activities supported in this program include implementation of clinical prototype devices, non-clinical safety and efficacy testing, design verification and validation activities, obtaining an Investigational Device Exemption (IDE) for a Significant Risk (SR) study or Institutional Review Board (IRB) approval for a Non-Significant Risk (NSR) study, as well as a subsequent small clinical study. The clinical study is...


Minor Use Minor Species Development of Drugs (R01)


BRAIN Initiative: Development and Validation of Novel Tools to Probe Cell-Specific and Circuit-Specific Processes in the Brain (R01 Clinical Trial Not Allowed)

Education; Health; Income Security and Social Services

Independent school districts; Public and State controlled institutions of higher education; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; For profit organizations other than small businesses; Small businesses; Public housing authorities/Indian housing authorities; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Private institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification); County governments; Native American tribal organizations (other than Federally recognized tribal governments); Special district governments; Native American tribal governments (Federally recognized); State governments; City or township governments

The purpose of this Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative is to encourage applications that will develop and validate novel tools to facilitate the detailed analysis of complex circuits and provide insights into cellular interactions that underlie brain function. The new tools and technologies should inform and/or exploit cell-type and/or circuit-level specificity. Plans for validating the utility of the tool/technology will be an essential feature of a successful application. The development of new genetic and non-genetic tools for delivering genes, proteins and chemicals to cells of interest or approaches that are expected to target specific ce...


GROWING CONVERGENCE RESEARCH


Mid-scale Research Infrastructure-1

Others (see text field entitled "Additional Information on Eligibility" for clarification)

NSF-supported science and engineering research increasingly relies on cutting-edge infrastructure. With its Major Research Instrumentation (MRI) program and Major Multi-user Facilities ("Major Facilities") projects, NSF supports infrastructure projects at the lower and higher range of infrastructure project costs, Foundation-wide, across science and engineering research disciplines. The Foundation-wide Mid-scale Research Infrastructure opportunity is intended to provide NSF with an agile, Foundation-wide process to fund experimental research capabilities in the mid-scale range between MRI and Major Multi-user Facilities. NSF defines Research Infrastructure (RI) as any combination of facil...


BRAIN Initiative: Exploratory Research Opportunities Using Invasive Neural Recording and Stimulating Technologies in the Human Brain (R61 Clinical Trial Not Allowed)


Advancing Global Health

Bureau of Global Health Security and Diplomacy


Ocean Technology and Interdisciplinary Coordination


Supporting Talented Early Career Researchers in Genomics (R01 Clinical Trial Optional)

County governments; Independent school districts; Public housing authorities/Indian housing authorities; Private institutions of higher education; City or township governments; Public and State controlled institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification); Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Small businesses; Special district governments; Native American tribal governments (Federally recognized); Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; For profit organizations other than small businesses; Native American tribal organizations (other than Federally recognized tribal governments); State governments

This Funding Opportunity Announcement is intended to identify and support research projects by exceptionally promising Early Stage Investigators with a long-term career interest in pursuing innovative research in genomics. This opportunity is open to research in all areas relevant to the mission of NHGRI, including genomic sciences, genomic medicine, genomic data science, and ethical, legal, and social implications of genomics.


Mid-Career Advancement


NSF Scholarships in Science, Technology, Engineering, and Mathematics Program


Coupling, Energetics, and Dynamics of Atmospheric Regions


Discovery of in vivo Chemical Probes for the Nervous System (R01 Clinical Trial Not Allowed)


High Priority HIV and Substance Use Research (RM1 Clinical Trial Optional)


High Priority HIV and Substance Use Research (R01 Clinical Trial Optional)


Development and Testing of Novel Interventions to Improve HIV Prevention, Treatment, and Program Implementation for People Who Use Substances (R34 Clinical Trial Required)


Air Delivered Effects


Innovations in Graduate Education (IGE) Program


Expeditions in Computing

The far-reaching impact and rate of innovation in the computer and information science and engineering ﬁelds has been remarkable, generating economic prosperity and enhancing the quality of life for people throughout the world. More than a decade ago, the National Science Foundation’s (NSF) Directorate for Computer and Information Science and Engineering (CISE) established the Expeditions in Computing (Expeditions) program to build on past successes and provide the CISE research and education community with the opportunity to pursue ambitious, fundamental research agendas that promise to deﬁne the future of computing and information. In planning Expeditions projects, i...


UNITED STATES MILITARY ACADEMY Broad Agency Announcement


NSF National Quantum Virtual Laboratory - Quantum Testbeds


Short Courses on Innovative Methodologies and Approaches in the Behavioral and Social Sciences (R25 Clinical Trials Not Allowed)

City or township governments; Native American tribal governments (Federally recognized); Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Native American tribal organizations (other than Federally recognized tribal governments); Public and State controlled institutions of higher education; Small businesses; State governments; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; County governments; Independent school districts; Public housing authorities/Indian housing authorities; Others (see text field entitled "Additional Information on Eligibility" for clarification); Private institutions of higher education; For profit organizations other than small businesses; Special district governments

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The overarching goal of this R25 program is to support educational activities that complement and/or enhance the training of a workforce to meet the nations biomedical, behavioral and clinical research needs. To accomplish the stated over-arching goal, this FOA will support creative educational activities with a primary focus on: Courses for Skills Development


EPSCoR Research Infrastructure Improvement (RII): EPSCoR Research Fellows


Findable Accessible Interoperable Reusable Open Science


Computational Approaches to Curation at Scale for Biomedical Research Assets (R01 Clinical Trial Not Allowed)

For profit organizations other than small businesses; Native American tribal governments (Federally recognized); Special district governments; County governments; Independent school districts; Others (see text field entitled "Additional Information on Eligibility" for clarification); Public and State controlled institutions of higher education; State governments; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Private institutions of higher education; City or township governments; Native American tribal organizations (other than Federally recognized tribal governments); Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Public housing authorities/Indian housing authorities; Small businesses

NLM wishes to accelerate access to, and availability of, secure, complete datasets and computational models that can serve as the basis for transformative biomedical discoveries. Innovative at-scale computational approaches that increase the speed and scope of curation processes are needed for data mining and knowledge discovery from growing quantities of biomedical data being produced from ongoing data science advances.


Emergency Competitive Revision to Existing NIH Awards (Emergency Supplement - Clinical Trial Optional)


Environmental Health Sciences Core Centers Program (P30 Clinical Trials Optional)


NHLBI Emerging Investigator Award (EIA) (R35 Clinical Trial Optional)


NHLBI Outstanding Investigator Award (OIA) (R35 Clinical Trial Optional)


LPS Qubit Collaboratory (LQC)


Independent Scientist Award (Parent K02 - Independent Clinical Trial Not Allowed)


Independent Scientist Award (Parent K02 - Independent Clinical Trial Required)


Interventions on Health and Healthcare Disparities on Non-Communicable and Chronic Diseases in Latin America: Improving Health Outcomes Across the Hemisphere (R01 - Clinical Trial Required)

Special district governments; Native American tribal governments (Federally recognized); Small businesses; Public and State controlled institutions of higher education; City or township governments; Others (see text field entitled "Additional Information on Eligibility" for clarification); Public housing authorities/Indian housing authorities; Private institutions of higher education; County governments; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Independent school districts; Native American tribal organizations (other than Federally recognized tribal governments); For profit organizations other than small businesses; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; State governments

The purpose of this Notice of Funding Opportunity (NOFO) is to support innovative and interdisciplinary research teams focused on clinical, health services, and/or community-based interventions that address health and healthcare disparities related to non-communicable and chronic diseases (NCDs) with the highest burden and mortality in Latin America and among U.S. Hispanics/Latinos. Multidisciplinary research teams would be expected to meaningfully collaborate with key partners that must include at least one PI or MPI from institutions in Latin America.


Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Not Allowed)


Mentored Quantitative Research Development Award (Parent K25 Independent Clinical Trial Not Allowed)

State governments; Special district governments; Public and State controlled institutions of higher education; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Independent school districts; For profit organizations other than small businesses; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Private institutions of higher education; Native American tribal organizations (other than Federally recognized tribal governments); County governments; Others (see text field entitled "Additional Information on Eligibility" for clarification); Small businesses; City or township governments; Native American tribal governments (Federally recognized); Public housing authorities/Indian housing authorities

<p>The purpose of the Mentored Quantitative Research Career Development Award (K25) is to attract to NIH-relevant research those investigators whose quantitative science and engineering research has thus far not been focused primarily on questions of health and disease. The K25 award will provide support and "protected time" for a period of supervised study and research for productive professionals with quantitative (e.g., mathematics, statistics, economics, computer science, imaging science, informatics, physics, chemistry) and engineering backgrounds to integrate their expertise with NIH-relevant research.This Funding Opportunity Announcement (FOA) is designed specifically for applicant...


Mentored Quantitative Research Development Award (Parent K25 Independent Clinical Trial Required)


Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Not Allowed)


Mentored Research Scientist Development Award (Parent K01 - Independent Clinical Trial Required)

Public and State controlled institutions of higher education; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Private institutions of higher education; Independent school districts; State governments; County governments; Public housing authorities/Indian housing authorities; City or township governments; Small businesses; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Native American tribal organizations (other than Federally recognized tribal governments); Native American tribal governments (Federally recognized); Special district governments; Others (see text field entitled "Additional Information on Eligibility" for clarification); For profit organizations other than small businesses

The purpose of the NIH Mentored Research Scientist Development Award (K01) is to provide support and protected time (three to five years) for an intensive, supervised career development experience in the biomedical, behavioral, or clinical sciences leading to research independence. Although all of the participating NIH Institutes and Centers (ICs) use this support mechanism to support career development experiences that lead to research independence, some ICs use the K01 award for individuals who propose to train in a new field or for individuals who have had a hiatus in their research career because of illness or pressing family circumstances.


Midcareer Investigator Award in Patient-Oriented Research (Parent K24 Independent Clinical Trial Not Allowed)


Midcareer Investigator Award in Patient-Oriented Research (Parent K24 Independent Clinical Trial Required)


NIDCD Mentored Career Development Award for Postdoctorate Au.D./Ph.D. Audiologists (K01 Clinical Trial Required)


NIDCD Mentored Career Development Award for Postdoctorate Au.D./Ph.D. Audiologists (K01 Independent Clinical Trial Not Allowed)


NIDCD Research Career Enhancement Award for Established Investigators (K18 Clinical Trial Not Allowed)


NIDCD Research Career Enhancement Award for Established Investigators (K18 Clinical Trial Required)


NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Not Allowed)


NIH Pathway to Independence Award (Parent K99/R00 Independent Clinical Trial Required)

Small businesses; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Public and State controlled institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification); Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; State governments; Native American tribal governments (Federally recognized); Native American tribal organizations (other than Federally recognized tribal governments); For profit organizations other than small businesses; Independent school districts; Private institutions of higher education; City or township governments; County governments; Special district governments; Public housing authorities/Indian housing authorities

The purpose of the NIH Pathway to Independence Award (K99/R00) program is to increase and maintain a strong cohort of new and talented, NIH-supported, independent investigators. This program is designed to facilitate a timely transition of outstanding postdoctoral researchers with a research and/or clinical doctorate degree from mentored, postdoctoral research positions to independent, tenure-track or equivalent faculty positions. The program will provide independent NIH research support during this transition in order to help awardees to launch competitive, independent research careers.


New Approaches for Measuring Brain Changes Across Longer Timespans (R01 Clinical Trial Optional)

Others (see text field entitled "Additional Information on Eligibility" for clarification); City or township governments; Public housing authorities/Indian housing authorities; Native American tribal organizations (other than Federally recognized tribal governments); State governments; County governments; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Public and State controlled institutions of higher education; Native American tribal governments (Federally recognized); Small businesses; Special district governments; Independent school districts; Private institutions of higher education; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; For profit organizations other than small businesses

The purpose of this funding opportunity is to encourage multidisciplinary investigators to develop new approaches or apply existing approaches in novel ways to measure brain activity, connectivity, genomics, or other aspects across the age spectrum of neurodevelopment. The overarching goal is to extend our understanding of brain development and aging, including studies of the neurodevelopmental origins of later health and disease. Research can include healthy human participants of any age, specific clinical groups such as those with cognitive, motor, or affective regulation challenges, and/or animal research on these domains of function. The studies can focus on longitudinal neuroanatomic...


New Approaches for Measuring Brain Changes Across Longer Timespans (R21 Clinical Trial Optional)

Independent school districts; County governments; City or township governments; Others (see text field entitled "Additional Information on Eligibility" for clarification); Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Public housing authorities/Indian housing authorities; Special district governments; Public and State controlled institutions of higher education; Native American tribal organizations (other than Federally recognized tribal governments); Small businesses; State governments; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Private institutions of higher education; Native American tribal governments (Federally recognized); For profit organizations other than small businesses

The purpose of this funding opportunity is to encourage multidisciplinary investigators to submit applications developing exploratory, highly novel new approaches, or innovative applications of existing approaches to measure brain activity, connectivity, genomics, or other aspects across the age spectrum of neurodevelopment. The overarching goal is to extend our understanding of brain development and aging, including studies of the neurodevelopmental origins of later health and disease, by improving repeated measures across longer epochs of the lifespan to better predict outcomes at later ages. . Research can include healthy human participants of any age, specific clinical groups such tho...


Pilot Health Services and Economic Research on the Treatment of Drug, Alcohol, and Tobacco Use Disorders (R34 Clinical Trial Optional)

County governments; Small businesses; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; City or township governments; Native American tribal organizations (other than Federally recognized tribal governments); Public housing authorities/Indian housing authorities; Others (see text field entitled "Additional Information on Eligibility" for clarification); Private institutions of higher education; Independent school districts; Special district governments; Public and State controlled institutions of higher education; Native American tribal governments (Federally recognized); Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; State governments; For profit organizations other than small businesses

This Notice of Funding Opportunity (NOFO) encourages pilot and preliminary research in preparation for larger-scale services research effectiveness trials. Relevant trials may test a wide range of approaches, including interventions, practices, and policies designed to optimize access to, and the quality, effectiveness, affordability and utilization of drug, tobacco, or alcohol use disorder treatments and related services, as well as services for comorbid medical and mental disorder conditions. Relevant approaches may include both those that are novel, and those that are commonly used in practice but lack an evidence base. This NOFO provides resources for assessing the feasibility, accept...


Screening, Brief Intervention and Referral to Treatment or Prevention (SBIRT/P) for alcohol, tobacco, and other drugs (ATOD) use and misuse in adult populations that experience health disparities (R01, Clinical Trial Required)

City or township governments; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; State governments; Special district governments; Native American tribal governments (Federally recognized); Independent school districts; Public and State controlled institutions of higher education; County governments; Others (see text field entitled "Additional Information on Eligibility" for clarification); For profit organizations other than small businesses; Native American tribal organizations (other than Federally recognized tribal governments); Private institutions of higher education; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Small businesses; Public housing authorities/Indian housing authorities

The Office of Disease Prevention (ODP) and participating National Institutes of Health (NIH) Institutes, Centers, and Offices (ICOs) are issuing this notice of funding opportunity (NOFO) seeking applications to test innovative approaches to implementing SBIRT/P for alcohol, tobacco, and other drugs (ATOD) use and misuse in adult populations that experience health disparities. SBIRT/P, (a term used for purposes of this funding announcement), involves screening individuals for risk of ATOD use and misuse, briefly intervening with a conversation about harmful substance use, and referring individuals for treatment or preventive services, as needed.

Proposed research should incl...


Summer Research Education Experience Program (R25 Clinical Trial Not Allowed)

Native American tribal governments (Federally recognized); Private institutions of higher education; For profit organizations other than small businesses; Small businesses; Others (see text field entitled "Additional Information on Eligibility" for clarification); Public and State controlled institutions of higher education; County governments; Independent school districts; State governments; Native American tribal organizations (other than Federally recognized tribal governments); Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Special district governments; City or township governments; Public housing authorities/Indian housing authorities; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The over-arching goal of this R25 program is to support educational activities that foster a better understanding of biomedical, behavioral and clinical research and its implications. To accomplish the stated over-arching goal, this FOA will support creative educational activities with a primary focus on research experiences for high school or undergraduate students or science teachers during the summer academic break. The proposed program needs to fit within the mission of the participating IC that the application is being submitted to and should not have a general STEM focus...


Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Not Allowed)


Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Required)


Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Required)


Risk and Protective Factors of Family Health and Family Level Interventions (R01 Clinical Trial Optional)

Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Small businesses; State governments; Native American tribal organizations (other than Federally recognized tribal governments); Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification); Independent school districts; County governments; Native American tribal governments (Federally recognized); Public and State controlled institutions of higher education; For profit organizations other than small businesses; Private institutions of higher education; City or township governments; Special district governments; Public housing authorities/Indian housing authorities

The purpose of this initiative is to advance the science of minority health and health disparities by supporting research on family health and well-being and resilience. The NIMHD Research Framework recognizes family health, family well-being, and family resilience as critically important areas of research to decrease disparities and promote equity.


NIA Expanding Research in AD/ADRD (ERA) Postbaccalaureate Research Education Program (R25 Independent Clinical Trial Not Allowed)


NIA Expanding Research in AD/ADRD (ERA) Summer Research Education Program (R25 Independent Clinical Trial Not Allowed)


Limited Competition: NCATS Clinical and Translational Science Award (CTSA) Program Research Education Grants Programs (R25 - Clinical Trial Not Allowed)

Public and State controlled institutions of higher education

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The overarching goal of this R25 program is to support educational activities that complement and/or enhance the training of a workforce to meet the nations biomedical, behavioral and clinical research needs.


High-End Instrumentation (HEI) Grant Program (S10 Clinical Trial Not Allowed)

Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification); Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Private institutions of higher education; Public and State controlled institutions of higher education

The High-End Instrumentation (HEI) Grant Program encourages applications from groups of NIH-supported investigators to purchase or upgrade a single item of high-end, specialized, commercially available instruments or integrated systems. The minimum award is $750,001. There is no maximum price limit for the instrument; however, the maximum award is $2,000,000. Instruments supported include, but are not limited to, nuclear magnetic resonance spectrometers, X-ray diffractometers, mass spectrometers, high throughput robotic screening systems, DNA and protein sequencers, biosensors, electron and light microscopes, flow cytometers, and biomedical imagers.


Limited Competition: Basic Instrumentation Grant (BIG) Program (S10 Clinical Trial Not Allowed)

Others (see text field entitled "Additional Information on Eligibility" for clarification); Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Private institutions of higher education; Public and State controlled institutions of higher education; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education

The Basic Instrumentation Grant (BIG) Program encourages applications from groups of NIH-supported investigators to purchase a single piece of new, costly, specialized, commercially available instrument or an integrated instrumentation system. The BIG Program is limited to institutions that have not received S10 instrumentation funding of $500,001 or greater in any of the preceding 3 Federal fiscal years (FY). Use the following to determine applicable funding periods: for submission in CY 2026, consider S10 funding in FYs 2023-2025; for submission in CY 2027, consider S10 funding in FYs 2024-2026; for submission in CY 2028, consider S10 funding in FYs 2025-2027. The minimum award is $25,0...


Shared Instrumentation Grant (SIG) Program (S10 Clinical Trial Not Allowed)


Enhancing Mechanistic Research on Precision Probiotic Therapies (R33 Clinical Trial Optional)

City or township governments; Small businesses; Native American tribal organizations (other than Federally recognized tribal governments); Private institutions of higher education; State governments; Public housing authorities/Indian housing authorities; For profit organizations other than small businesses; Special district governments; Native American tribal governments (Federally recognized); County governments; Public and State controlled institutions of higher education; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Independent school districts; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification)

The purpose of this notice of funding opportunity (NOFO) is to support highly innovative mechanistic research to accelerate precision probiotic interventions. Specifically, this NOFO solicits R33 applications that will characterize person-specific features affecting probiotic responses to identify subgroups of probiotic responders and to enhance probiotic clinical outcomes. The ultimate goal of this NOFO is to identify, understand, and develop strategies to address barriers in precision probiotic therapies to account for the heterogenicity in humans that causes inconsistent probiotic responses. This NOFO will support studies to assess the ability of the unique patterns of host biology (e....


Enhancing Mechanistic Research on Precision Probiotic Therapies (R61/R33 Clinical Trial Optional)

Small businesses; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Independent school districts; For profit organizations other than small businesses; Special district governments; Public and State controlled institutions of higher education; Native American tribal organizations (other than Federally recognized tribal governments); County governments; Private institutions of higher education; City or township governments; Others (see text field entitled "Additional Information on Eligibility" for clarification); State governments; Public housing authorities/Indian housing authorities; Native American tribal governments (Federally recognized)

The purpose of this notice of funding opportunity (NOFO) is to support highly innovative mechanistic research to accelerate precision probiotic interventions using a milestone-driven, biphasic award mechanism, R61/R33 Phased Innovation Award. Specifically, this NOFO solicits applications that will characterize person-specific features affecting probiotic responses to identify subgroups of probiotic responders and to enhance probiotic clinical outcomes. The ultimate goal of this NOFO is to identify, understand, and develop strategies to address barriers in precision probiotic therapies to account for the heterogenicity in humans that causes inconsistent probiotic responses. The first phase...


NIGMS National and Regional Resources (R24 - Clinical Trial Not Allowed)

Public and State controlled institutions of higher education; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification); For profit organizations other than small businesses; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Private institutions of higher education; Native American tribal governments (Federally recognized); Public housing authorities/Indian housing authorities; State governments; Native American tribal organizations (other than Federally recognized tribal governments); Special district governments; Small businesses; City or township governments; Independent school districts; County governments

This Notice of Funding Opportunity (NOFO) encourages applications for support of resources that will provide access to state-of-the-art equipment, technologies, research tools, materials, organisms, software, and/or services to a substantial regional (multi-state) or national user base. Only those resources with technical capabilities that fall within the NIGMS-supported program areas are eligible for awards. The resources should already be established or may be formed through consolidation of existing local or regional facilities. The intent is to provide resource access to investigators without regard to the specific biomedical focus of their research, while not duplicating or replacing...


Early-Stage Dissemination and Implementation Research in Communication Disorders (R21 Clinical Trial Optional)


Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)

Native American tribal governments (Federally recognized); City or township governments; For profit organizations other than small businesses; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Private institutions of higher education; Public housing authorities/Indian housing authorities; Special district governments; Small businesses; Independent school districts; State governments; Public and State controlled institutions of higher education; Native American tribal organizations (other than Federally recognized tribal governments); County governments; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification)

The National Institutes of Health (NIH) hereby notifies recipient organizations holding specific types of NIH grants, listed within the Activity Code section above, that applications for change of recipient organization may be submitted to this NOFO. This assumes such a change is programmatically permitted for the particular grant. Applications for change of recipient organization are considered prior approval requests (as described in Section 8.1.2.7 of the NIH Grants Policy Statement) and will be routed for consideration directly to the Grants Management Specialist named in the current award. Although requests for change of recipient organization may be submitted through this NOFO, ther...


NHLBI Career Transition Award for Intramural Postdoctoral Fellows and Research Trainees (K22 Clinical Trial Required)

City or township governments; For profit organizations other than small businesses; Others (see text field entitled "Additional Information on Eligibility" for clarification); Native American tribal governments (Federally recognized); Independent school districts; Private institutions of higher education; State governments; Public and State controlled institutions of higher education; Small businesses; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Native American tribal organizations (other than Federally recognized tribal governments); Public housing authorities/Indian housing authorities; Special district governments; County governments; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education

The purpose of the NHLBI Career Transition Award (K22) program is to provide highly qualified postdoctoral fellows in the NHLBI Division of Intramural Research the opportunity to transition their research programs as new investigators to extramural institutions. To achieve these objectives, the NHLBI Career Transition Award will support two phases of research: a mentored intramural phase (up to two years) and an extramural phase (three years), for a total of five years of combined support. Transition from the intramural phase of support to the extramural phase is not automatic. Approval of the transition will be based on the success of the awardee's research program during the mentored ph...


NHLBI Career Transition Award for Intramural Postdoctoral Fellows and Research Trainees (K22 Independent Clinical Trial Not Allowed)

Special district governments; Private institutions of higher education; Native American tribal governments (Federally recognized); Public housing authorities/Indian housing authorities; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; City or township governments; Native American tribal organizations (other than Federally recognized tribal governments); Small businesses; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; For profit organizations other than small businesses; Public and State controlled institutions of higher education; Independent school districts; Others (see text field entitled "Additional Information on Eligibility" for clarification); State governments; County governments

To provide highly qualified postdoctoral fellows and other doctoral-level researchers currently in training in the NHLBI Division of Intramural Research with the opportunity to transition their research programs to extramural institutions as junior investigators.


Successor-in-Interest (Type 6 Parent Clinical Trial Optional)

Others (see text field entitled "Additional Information on Eligibility" for clarification); Small businesses; Native American tribal governments (Federally recognized); Native American tribal organizations (other than Federally recognized tribal governments); Private institutions of higher education; For profit organizations other than small businesses; Public and State controlled institutions of higher education; State governments; Public housing authorities/Indian housing authorities; Independent school districts; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; County governments; City or township governments; Special district governments; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education

The National Institutes of Health (NIH) hereby notify recipient organizations holding specific types of NIH grants, listed in the full Funding Opportunity Announcement (FOA), that applications for change of recipient organization status, often referred to in this announcement as Successor-In-Interest, may be submitted to this NOFO. Applications for change of recipient organization status are considered prior approval requests (as described in Section 8.1.2.8 of the NIH Grants Policy Statement) and will be routed for consideration directly to the Grants Management Specialist named in the current award.Although successor-in-interest requests may be submitted through this NOFO, there is no g...


Cutting-Edge Basic Research Awards (CEBRA) (R21 Clinical Trial Optional)

Native American tribal governments (Federally recognized); Native American tribal organizations (other than Federally recognized tribal governments); Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Small businesses; City or township governments; Others (see text field entitled "Additional Information on Eligibility" for clarification); County governments; Special district governments; Private institutions of higher education; Public housing authorities/Indian housing authorities; For profit organizations other than small businesses; State governments; Independent school districts; Public and State controlled institutions of higher education; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education

<p>The National Institute on Drug Abuse (NIDA) Cutting-Edge Basic Research Award (CEBRA) is designed to foster highly innovative or conceptually creative research related to the etiology, pathophysiology, prevention, or treatment of substance use disorders (SUDs). It supports high-risk and potentially high-impact research that is sparse or not included in NIDA's current portfolio that has the potential to transform SUD research. The proposed research should: 1. develop, and/or adapt, revolutionary techniques or methods for addiction research or that show promising future applicability to SUD research; and /or 2. test an innovative and significant hypothesis for which there are scant prece...