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feat: Initial dev
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- .gitignore +4 -1
- openenv-polypharmacy/.dockerignore +8 -0
- openenv-polypharmacy/.env.example +3 -0
- openenv-polypharmacy/Dockerfile +21 -12
- openenv-polypharmacy/README.md +174 -113
- openenv-polypharmacy/backend/Dockerfile +28 -0
- openenv-polypharmacy/backend/__init__.py +1 -0
- openenv-polypharmacy/backend/main.py +15 -0
- openenv-polypharmacy/{src/polypharmacy_env.egg-info/requires.txt β backend/requirements.txt} +3 -5
- openenv-polypharmacy/{src β backend/src}/polypharmacy_env/__init__.py +0 -0
- openenv-polypharmacy/{src β backend/src}/polypharmacy_env/api/__init__.py +0 -0
- openenv-polypharmacy/backend/src/polypharmacy_env/api/app.py +63 -0
- openenv-polypharmacy/backend/src/polypharmacy_env/api/routes/__init__.py +1 -0
- openenv-polypharmacy/backend/src/polypharmacy_env/api/routes/agent.py +35 -0
- openenv-polypharmacy/backend/src/polypharmacy_env/api/server.py +6 -0
- openenv-polypharmacy/{src β backend/src}/polypharmacy_env/baselines/__init__.py +0 -0
- openenv-polypharmacy/{src β backend/src}/polypharmacy_env/baselines/heuristic_agent.py +0 -0
- openenv-polypharmacy/{src β backend/src}/polypharmacy_env/baselines/random_agent.py +0 -0
- openenv-polypharmacy/{src β backend/src}/polypharmacy_env/client.py +0 -0
- openenv-polypharmacy/{src β backend/src}/polypharmacy_env/config.py +1 -1
- openenv-polypharmacy/{src β backend/src}/polypharmacy_env/data_loader.py +0 -0
- openenv-polypharmacy/{src β backend/src}/polypharmacy_env/ddi_simulator.py +0 -0
- openenv-polypharmacy/{src β backend/src}/polypharmacy_env/env_core.py +0 -0
- openenv-polypharmacy/{src β backend/src}/polypharmacy_env/graders.py +0 -0
- openenv-polypharmacy/{src β backend/src}/polypharmacy_env/models.py +0 -0
- openenv-polypharmacy/{src β backend/src}/polypharmacy_env/rewards.py +0 -0
- openenv-polypharmacy/backend/src/polypharmacy_env/services/__init__.py +1 -0
- openenv-polypharmacy/backend/src/polypharmacy_env/services/groq_agent.py +246 -0
- openenv-polypharmacy/{src β backend/src}/polypharmacy_env/tasks.py +0 -0
- openenv-polypharmacy/{src β backend/src}/polypharmacy_env/tests/__init__.py +0 -0
- openenv-polypharmacy/{src β backend/src}/polypharmacy_env/tests/test_api.py +0 -0
- openenv-polypharmacy/{src β backend/src}/polypharmacy_env/tests/test_env_core.py +0 -0
- openenv-polypharmacy/data/processed/patients_polypharmacy.csv +29 -29
- openenv-polypharmacy/docker-compose.yml +35 -0
- openenv-polypharmacy/frontend/Dockerfile +12 -0
- openenv-polypharmacy/frontend/index.html +12 -0
- openenv-polypharmacy/frontend/package-lock.json +1677 -0
- openenv-polypharmacy/frontend/package.json +19 -0
- openenv-polypharmacy/frontend/src/App.jsx +371 -0
- openenv-polypharmacy/frontend/src/main.jsx +10 -0
- openenv-polypharmacy/frontend/src/styles.css +304 -0
- openenv-polypharmacy/frontend/vite.config.js +10 -0
- openenv-polypharmacy/inference.py +11 -15
- openenv-polypharmacy/openenv.yaml +1 -1
- openenv-polypharmacy/pyproject.toml +4 -3
- openenv-polypharmacy/requirements.txt +1 -8
- openenv-polypharmacy/scripts/dev_backend.sh +4 -0
- openenv-polypharmacy/scripts/dev_frontend.sh +5 -0
- openenv-polypharmacy/scripts/inference.py +0 -217
- openenv-polypharmacy/scripts/run_validation.sh +2 -2
.gitignore
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venv/
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.DS_Store
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__pycache__/
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venv/
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__pycache__/
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node_modules/
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dist/
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.env
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openenv-polypharmacy/.dockerignore
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.git
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**/__pycache__/
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**/.pytest_cache/
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**/.DS_Store
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.env
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frontend/node_modules
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frontend/dist
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openenv-polypharmacy/.env.example
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GROQ_API_KEY=your_groq_api_key_here
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GROQ_BASE_URL=https://api.groq.com/openai/v1
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GROQ_MODEL_NAME=llama-3.3-70b-versatile
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openenv-polypharmacy/Dockerfile
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FROM python:3.11-slim
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# System deps
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RUN apt-get update && \
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apt-get install -y --no-install-recommends build-essential curl && \
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rm -rf /var/lib/apt/lists/*
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WORKDIR /app
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# Environment
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ENV PORT=7860
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ENV PYTHONPATH="/app/src:${PYTHONPATH}"
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ENV PYTHONUNBUFFERED=1
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EXPOSE 7860
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HEALTHCHECK --interval=30s --timeout=3s --start-period=
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CMD curl -f http://localhost:7860/health || exit 1
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CMD ["
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FROM node:20-alpine AS frontend-builder
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WORKDIR /app/frontend
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COPY frontend/package*.json ./
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RUN npm ci
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COPY frontend/ ./
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RUN npm run build
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FROM python:3.11-slim
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RUN apt-get update && \
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apt-get install -y --no-install-recommends build-essential curl && \
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rm -rf /var/lib/apt/lists/*
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WORKDIR /app
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COPY backend/requirements.txt /app/backend/requirements.txt
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RUN pip install --no-cache-dir -r /app/backend/requirements.txt
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COPY backend /app/backend
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COPY data /app/data
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COPY scripts /app/scripts
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COPY openenv.yaml /app/openenv.yaml
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COPY .env.example /app/.env.example
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COPY inference.py /app/inference.py
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COPY --from=frontend-builder /app/frontend/dist /app/frontend/dist
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RUN python3 /app/scripts/preprocess_data.py
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ENV PORT=7860
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ENV PYTHONPATH="/app/backend/src:${PYTHONPATH}"
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ENV PYTHONUNBUFFERED=1
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EXPOSE 7860
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HEALTHCHECK --interval=30s --timeout=3s --start-period=15s --retries=3 \
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CMD curl -f http://localhost:7860/health || exit 1
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CMD ["sh", "-c", "uvicorn backend.main:app --host 0.0.0.0 --port ${PORT:-7860}"]
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openenv-polypharmacy/README.md
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# PolypharmacyEnv
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Polypharmacy (concurrent use of multiple medications) is extremely common in elderly patients (age >= 65) and carries significant risks:
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- **Drug-drug interactions** can cause adverse events, hospitalisation, and death.
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- Stopping critical medications (anticoagulants, insulin) without proper substitution can be equally dangerous.
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This environment lets RL and LLM-based agents learn to **balance risk reduction against regimen stability**.
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---
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##
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Each step, the agent sends a `PolypharmacyAction` with one of three action types:
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---
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##
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| `complex_tradeoff` | Hard | 10-15 | 12 | 5 | 30 | Critical drugs, trade-off between risk and regimen stability |
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| Successful intervention | +(previous_risk - new_risk) - 0.02 cost |
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```
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```bash
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```
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---
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| `easy_screening` | ~0.96 | ~1.30 |
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| `complex_tradeoff` | ~0.24 | ~0.11 |
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---
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##
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```
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pyproject.toml
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src/polypharmacy_env/
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config.py # Constants, task configs
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models.py # Pydantic action/observation/state models
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env_core.py # PolypharmacyEnv implementation
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tasks.py # Task selection utilities
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graders.py # Deterministic graders (3 difficulty levels)
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rewards.py # Reward shaping logic
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data_loader.py # CSV data loading
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ddi_simulator.py # Drug interaction lookup engine
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api/
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server.py # FastAPI HTTP server
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schemas.py # Request/response schemas
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baselines/
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heuristic_agent.py # Rule-based baseline
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random_agent.py # Random baseline
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tests/
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test_env_core.py
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test_api.py
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data/
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lookups/ # Drug metadata, DDI rules, Beers criteria CSVs
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processed/ # Synthetic patient episodes
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scripts/
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preprocess_data.py # Synthetic data generator
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run_validation.sh # Run tests + baseline
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```
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# PolypharmacyEnv
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Monorepo for an OpenEnv-compatible medication safety environment with:
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- a FastAPI backend (`backend/`)
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- a React frontend (`frontend/`)
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- data assets (`data/`)
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- utility scripts (`scripts/`)
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---
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## Repository Structure
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```text
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openenv-polypharmacy/
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backend/
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main.py # ASGI entrypoint (uvicorn target)
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requirements.txt # Backend dependencies
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Dockerfile # Backend container
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src/polypharmacy_env/ # Python package source
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api/
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app.py # FastAPI/OpenEnv app assembly
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server.py # Compatibility import wrapper
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routes/agent.py # /agent/suggest route
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services/
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groq_agent.py # Groq-based action suggestion logic
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env_core.py # OpenEnv environment core
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models.py # Action/observation/state models
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data_loader.py # CSV loading
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ddi_simulator.py # DDI and Beers lookups
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rewards.py # Reward shaping
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graders.py # Task graders
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tasks.py # Task/episode selection
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tests/ # Backend tests
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frontend/
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src/ # React UI code
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package.json
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Dockerfile # Frontend container
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data/
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lookups/ # drug_metadata.csv, ddi_rules.csv, beers_criteria.csv
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processed/ # patients_polypharmacy.csv
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scripts/
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preprocess_data.py # Synthetic data generation
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dev_backend.sh # Local backend run helper
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dev_frontend.sh # Local frontend run helper
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run_validation.sh # Tests + baseline validation
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docker-compose.yml # Full stack orchestration
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openenv.yaml # OpenEnv manifest
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inference.py # Optional CLI inference baseline
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.env.example # Environment template
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```
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---
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+
## What It Does
|
| 56 |
|
| 57 |
+
The environment simulates elderly polypharmacy review. Agent actions:
|
| 58 |
|
| 59 |
+
- `query_ddi`
|
| 60 |
+
- `propose_intervention`
|
| 61 |
+
- `finish_review`
|
|
|
|
|
|
|
| 62 |
|
| 63 |
+
Supported tasks:
|
| 64 |
|
| 65 |
+
- `easy_screening`
|
| 66 |
+
- `budgeted_screening`
|
| 67 |
+
- `complex_tradeoff`
|
| 68 |
|
| 69 |
---
|
| 70 |
|
| 71 |
+
## Prerequisites
|
| 72 |
|
| 73 |
+
- Python 3.10+
|
| 74 |
+
- Node.js 18+ (or 20+ recommended)
|
| 75 |
+
- npm
|
| 76 |
+
- Docker + Docker Compose (optional, for containerized run)
|
|
|
|
| 77 |
|
| 78 |
---
|
| 79 |
|
| 80 |
+
## Environment Setup
|
| 81 |
|
| 82 |
+
Create `.env`:
|
| 83 |
|
| 84 |
+
```bash
|
| 85 |
+
cp .env.example .env
|
| 86 |
+
```
|
|
|
|
|
|
|
|
|
|
|
|
|
| 87 |
|
| 88 |
+
Set values:
|
| 89 |
+
|
| 90 |
+
- `GROQ_API_KEY=...` (required)
|
| 91 |
+
- `GROQ_BASE_URL=https://api.groq.com/openai/v1` (recommended)
|
| 92 |
+
- `GROQ_MODEL_NAME=llama-3.3-70b-versatile` (recommended)
|
| 93 |
|
| 94 |
---
|
| 95 |
|
| 96 |
+
## Local Run (Recommended During Development)
|
| 97 |
+
|
| 98 |
+
### 1) Install dependencies
|
| 99 |
|
| 100 |
+
Backend:
|
| 101 |
|
| 102 |
```bash
|
| 103 |
+
pip install -r backend/requirements.txt
|
| 104 |
```
|
| 105 |
|
| 106 |
+
Frontend:
|
| 107 |
|
| 108 |
```bash
|
| 109 |
+
cd frontend
|
| 110 |
+
npm install
|
| 111 |
+
cd ..
|
| 112 |
```
|
| 113 |
|
| 114 |
+
### 2) Generate/update synthetic data (if needed)
|
| 115 |
|
| 116 |
```bash
|
| 117 |
+
python scripts/preprocess_data.py
|
| 118 |
```
|
| 119 |
|
| 120 |
+
### 3) Start services in two terminals
|
| 121 |
+
|
| 122 |
+
Terminal A:
|
| 123 |
|
| 124 |
```bash
|
| 125 |
+
./scripts/dev_backend.sh
|
| 126 |
```
|
| 127 |
|
| 128 |
+
Terminal B:
|
| 129 |
|
| 130 |
```bash
|
| 131 |
+
./scripts/dev_frontend.sh
|
| 132 |
```
|
| 133 |
|
| 134 |
+
### 4) Open app
|
| 135 |
+
|
| 136 |
+
- Frontend: [http://localhost:5173](http://localhost:5173)
|
| 137 |
+
- Backend health: [http://localhost:7860/health](http://localhost:7860/health)
|
| 138 |
+
|
| 139 |
+
---
|
| 140 |
+
|
| 141 |
+
## Docker Run
|
| 142 |
+
|
| 143 |
+
Run both services:
|
| 144 |
|
| 145 |
```bash
|
| 146 |
+
docker compose up --build
|
|
|
|
|
|
|
|
|
|
|
|
|
| 147 |
```
|
| 148 |
|
| 149 |
+
Stop:
|
| 150 |
|
| 151 |
```bash
|
| 152 |
+
docker compose down
|
|
|
|
| 153 |
```
|
| 154 |
|
| 155 |
+
Ports:
|
| 156 |
+
|
| 157 |
+
- backend: `7860`
|
| 158 |
+
- frontend: `5173`
|
| 159 |
+
|
| 160 |
---
|
| 161 |
|
| 162 |
+
## Hugging Face Spaces Deployment (Docker)
|
| 163 |
+
|
| 164 |
+
This repo now includes a **root `Dockerfile`** that builds frontend + backend into one container, so Spaces can host both API and UI together.
|
| 165 |
+
|
| 166 |
+
### 1) Create a new Space
|
| 167 |
|
| 168 |
+
- Go to [Hugging Face Spaces](https://huggingface.co/new-space)
|
| 169 |
+
- Choose **Docker** SDK
|
| 170 |
+
- Create the Space
|
| 171 |
|
| 172 |
+
### 2) Add Space secrets/variables
|
| 173 |
+
|
| 174 |
+
In Space Settings -> Variables and Secrets:
|
| 175 |
+
|
| 176 |
+
- Secret: `GROQ_API_KEY`
|
| 177 |
+
- Variable: `GROQ_BASE_URL=https://api.groq.com/openai/v1`
|
| 178 |
+
- Variable: `GROQ_MODEL_NAME=llama-3.3-70b-versatile`
|
| 179 |
+
|
| 180 |
+
### 3) Push this repository to the Space
|
| 181 |
+
|
| 182 |
+
Commit and push all files, including root `Dockerfile`.
|
| 183 |
+
|
| 184 |
+
### 4) Verify after build
|
| 185 |
+
|
| 186 |
+
- Space root URL loads the React UI
|
| 187 |
+
- `/health` returns healthy status
|
| 188 |
+
- OpenEnv endpoints are available (`/reset`, `/step`, `/state`, `/schema`)
|
| 189 |
+
|
| 190 |
+
Notes:
|
| 191 |
+
|
| 192 |
+
- Container reads `PORT` (defaults to `7860`) which is Space-friendly.
|
| 193 |
+
- Frontend static assets are served by FastAPI from `frontend/dist`.
|
| 194 |
|
| 195 |
---
|
| 196 |
|
| 197 |
+
## API Endpoints
|
| 198 |
+
|
| 199 |
+
OpenEnv/health:
|
| 200 |
|
| 201 |
+
- `POST /reset`
|
| 202 |
+
- `POST /step`
|
| 203 |
+
- `GET /state`
|
| 204 |
+
- `GET /health`
|
| 205 |
+
- `GET /schema`
|
| 206 |
+
- `WS /ws` (stateful session)
|
| 207 |
|
| 208 |
+
AI helper:
|
|
|
|
|
|
|
|
|
|
|
|
|
| 209 |
|
| 210 |
+
- `POST /agent/suggest`
|
| 211 |
|
| 212 |
---
|
| 213 |
|
| 214 |
+
## Testing
|
| 215 |
+
|
| 216 |
+
Run backend tests:
|
| 217 |
|
| 218 |
+
```bash
|
| 219 |
+
python -m pytest backend/src/polypharmacy_env/tests -v
|
| 220 |
```
|
| 221 |
+
|
| 222 |
+
Or run validation script:
|
| 223 |
+
|
| 224 |
+
```bash
|
| 225 |
+
./scripts/run_validation.sh
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 226 |
```
|
| 227 |
+
|
| 228 |
+
---
|
| 229 |
+
|
| 230 |
+
## Notes
|
| 231 |
+
|
| 232 |
+
- OpenEnv HTTP reset/step is stateless; multi-step episode continuity should use websocket (`/ws`).
|
| 233 |
+
- The frontend uses websocket for episode continuity and HTTP for AI suggestion.
|
| 234 |
+
- AI behavior includes rule-based guardrails to avoid repetitive low-value loops.
|
| 235 |
+
|
| 236 |
+
---
|
| 237 |
+
|
| 238 |
+
## Troubleshooting
|
| 239 |
+
|
| 240 |
+
- `ModuleNotFoundError: polypharmacy_env`
|
| 241 |
+
- Start backend using `./scripts/dev_backend.sh` from repo root.
|
| 242 |
+
- `/agent/suggest` fails
|
| 243 |
+
- Check `.env` keys and restart backend.
|
| 244 |
+
- UI state looks stale
|
| 245 |
+
- Hard refresh browser and click `Reset Episode`.
|
openenv-polypharmacy/backend/Dockerfile
ADDED
|
@@ -0,0 +1,28 @@
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 1 |
+
FROM python:3.11-slim
|
| 2 |
+
|
| 3 |
+
RUN apt-get update && \
|
| 4 |
+
apt-get install -y --no-install-recommends build-essential curl && \
|
| 5 |
+
rm -rf /var/lib/apt/lists/*
|
| 6 |
+
|
| 7 |
+
WORKDIR /app
|
| 8 |
+
|
| 9 |
+
COPY backend/requirements.txt /app/backend/requirements.txt
|
| 10 |
+
RUN pip install --no-cache-dir -r /app/backend/requirements.txt
|
| 11 |
+
|
| 12 |
+
COPY backend /app/backend
|
| 13 |
+
COPY data /app/data
|
| 14 |
+
COPY scripts /app/scripts
|
| 15 |
+
COPY .env.example /app/.env.example
|
| 16 |
+
|
| 17 |
+
RUN python3 /app/scripts/preprocess_data.py
|
| 18 |
+
|
| 19 |
+
ENV PORT=7860
|
| 20 |
+
ENV PYTHONPATH="/app/backend/src:${PYTHONPATH}"
|
| 21 |
+
ENV PYTHONUNBUFFERED=1
|
| 22 |
+
|
| 23 |
+
EXPOSE 7860
|
| 24 |
+
|
| 25 |
+
HEALTHCHECK --interval=30s --timeout=3s --start-period=10s --retries=3 \
|
| 26 |
+
CMD curl -f http://localhost:7860/health || exit 1
|
| 27 |
+
|
| 28 |
+
CMD ["uvicorn", "backend.main:app", "--host", "0.0.0.0", "--port", "7860"]
|
openenv-polypharmacy/backend/__init__.py
ADDED
|
@@ -0,0 +1 @@
|
|
|
|
|
|
|
| 1 |
+
"""Backend entrypoint package for monorepo structure."""
|
openenv-polypharmacy/backend/main.py
ADDED
|
@@ -0,0 +1,15 @@
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 1 |
+
"""ASGI entrypoint for backend service in monorepo layout."""
|
| 2 |
+
|
| 3 |
+
from __future__ import annotations
|
| 4 |
+
|
| 5 |
+
import sys
|
| 6 |
+
from pathlib import Path
|
| 7 |
+
|
| 8 |
+
BACKEND_DIR = Path(__file__).resolve().parent
|
| 9 |
+
SRC = BACKEND_DIR / "src"
|
| 10 |
+
if str(SRC) not in sys.path:
|
| 11 |
+
sys.path.insert(0, str(SRC))
|
| 12 |
+
|
| 13 |
+
from polypharmacy_env.api.app import app # noqa: E402
|
| 14 |
+
|
| 15 |
+
__all__ = ["app"]
|
openenv-polypharmacy/{src/polypharmacy_env.egg-info/requires.txt β backend/requirements.txt}
RENAMED
|
@@ -2,10 +2,8 @@ fastapi>=0.104.0
|
|
| 2 |
uvicorn>=0.24.0
|
| 3 |
pydantic>=2.0.0
|
| 4 |
requests>=2.31.0
|
|
|
|
|
|
|
| 5 |
openai>=1.0.0
|
| 6 |
-
|
| 7 |
-
[dev]
|
| 8 |
pytest>=7.0.0
|
| 9 |
-
httpx>=0.25.0
|
| 10 |
-
black
|
| 11 |
-
isort
|
|
|
|
| 2 |
uvicorn>=0.24.0
|
| 3 |
pydantic>=2.0.0
|
| 4 |
requests>=2.31.0
|
| 5 |
+
httpx>=0.25.0
|
| 6 |
+
openenv-core>=0.2.0
|
| 7 |
openai>=1.0.0
|
| 8 |
+
python-dotenv>=1.0.0
|
|
|
|
| 9 |
pytest>=7.0.0
|
|
|
|
|
|
|
|
|
openenv-polypharmacy/{src β backend/src}/polypharmacy_env/__init__.py
RENAMED
|
File without changes
|
openenv-polypharmacy/{src β backend/src}/polypharmacy_env/api/__init__.py
RENAMED
|
File without changes
|
openenv-polypharmacy/backend/src/polypharmacy_env/api/app.py
ADDED
|
@@ -0,0 +1,63 @@
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 1 |
+
"""FastAPI app factory for PolypharmacyEnv."""
|
| 2 |
+
|
| 3 |
+
from __future__ import annotations
|
| 4 |
+
|
| 5 |
+
from pathlib import Path
|
| 6 |
+
|
| 7 |
+
from dotenv import load_dotenv
|
| 8 |
+
from fastapi import HTTPException
|
| 9 |
+
from fastapi.middleware.cors import CORSMiddleware
|
| 10 |
+
from fastapi.staticfiles import StaticFiles
|
| 11 |
+
from openenv.core.env_server.http_server import create_app
|
| 12 |
+
from starlette.responses import FileResponse
|
| 13 |
+
|
| 14 |
+
from ..env_core import PolypharmacyEnv
|
| 15 |
+
from ..models import PolypharmacyAction, PolypharmacyObservation
|
| 16 |
+
from .routes.agent import router as agent_router
|
| 17 |
+
|
| 18 |
+
load_dotenv()
|
| 19 |
+
|
| 20 |
+
|
| 21 |
+
class SPAStaticFiles(StaticFiles):
|
| 22 |
+
"""Serve SPA index for unknown frontend routes."""
|
| 23 |
+
|
| 24 |
+
async def get_response(self, path: str, scope):
|
| 25 |
+
response = await super().get_response(path, scope)
|
| 26 |
+
if response.status_code != 404:
|
| 27 |
+
return response
|
| 28 |
+
index_path = Path(self.directory) / "index.html"
|
| 29 |
+
if index_path.exists():
|
| 30 |
+
return FileResponse(index_path)
|
| 31 |
+
raise HTTPException(status_code=404, detail="Not Found")
|
| 32 |
+
|
| 33 |
+
|
| 34 |
+
def create_polypharmacy_app():
|
| 35 |
+
app = create_app(
|
| 36 |
+
PolypharmacyEnv,
|
| 37 |
+
PolypharmacyAction,
|
| 38 |
+
PolypharmacyObservation,
|
| 39 |
+
env_name="polypharmacy_env",
|
| 40 |
+
)
|
| 41 |
+
|
| 42 |
+
app.add_middleware(
|
| 43 |
+
CORSMiddleware,
|
| 44 |
+
allow_origins=[
|
| 45 |
+
"http://localhost:5173",
|
| 46 |
+
"http://127.0.0.1:5173",
|
| 47 |
+
],
|
| 48 |
+
allow_credentials=True,
|
| 49 |
+
allow_methods=["*"],
|
| 50 |
+
allow_headers=["*"],
|
| 51 |
+
)
|
| 52 |
+
app.include_router(agent_router)
|
| 53 |
+
|
| 54 |
+
# In Docker Space deployment, serve built frontend from same container.
|
| 55 |
+
project_root = Path(__file__).resolve().parents[4]
|
| 56 |
+
frontend_dist = project_root / "frontend" / "dist"
|
| 57 |
+
if frontend_dist.exists():
|
| 58 |
+
app.mount("/", SPAStaticFiles(directory=frontend_dist, html=True), name="frontend")
|
| 59 |
+
|
| 60 |
+
return app
|
| 61 |
+
|
| 62 |
+
|
| 63 |
+
app = create_polypharmacy_app()
|
openenv-polypharmacy/backend/src/polypharmacy_env/api/routes/__init__.py
ADDED
|
@@ -0,0 +1 @@
|
|
|
|
|
|
|
| 1 |
+
"""API route modules."""
|
openenv-polypharmacy/backend/src/polypharmacy_env/api/routes/agent.py
ADDED
|
@@ -0,0 +1,35 @@
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 1 |
+
"""Agent suggestion API routes."""
|
| 2 |
+
|
| 3 |
+
from __future__ import annotations
|
| 4 |
+
|
| 5 |
+
from fastapi import APIRouter, HTTPException
|
| 6 |
+
from pydantic import BaseModel, Field
|
| 7 |
+
|
| 8 |
+
from ...models import PolypharmacyAction, PolypharmacyObservation
|
| 9 |
+
from ...services.groq_agent import suggest_action_from_observation
|
| 10 |
+
|
| 11 |
+
router = APIRouter(prefix="/agent", tags=["agent"])
|
| 12 |
+
|
| 13 |
+
|
| 14 |
+
class AgentSuggestRequest(BaseModel):
|
| 15 |
+
observation: PolypharmacyObservation
|
| 16 |
+
model_name: str | None = None
|
| 17 |
+
|
| 18 |
+
|
| 19 |
+
class AgentSuggestResponse(BaseModel):
|
| 20 |
+
action: PolypharmacyAction
|
| 21 |
+
source: str = Field(default="groq")
|
| 22 |
+
|
| 23 |
+
|
| 24 |
+
@router.post("/suggest", response_model=AgentSuggestResponse)
|
| 25 |
+
def suggest_agent_action(payload: AgentSuggestRequest) -> AgentSuggestResponse:
|
| 26 |
+
"""Return a model-suggested action for the current observation."""
|
| 27 |
+
try:
|
| 28 |
+
action = suggest_action_from_observation(
|
| 29 |
+
payload.observation, model_name=payload.model_name
|
| 30 |
+
)
|
| 31 |
+
except ValueError as exc:
|
| 32 |
+
raise HTTPException(status_code=400, detail=str(exc)) from exc
|
| 33 |
+
except Exception as exc:
|
| 34 |
+
raise HTTPException(status_code=500, detail=f"Model call failed: {exc}") from exc
|
| 35 |
+
return AgentSuggestResponse(action=action)
|
openenv-polypharmacy/backend/src/polypharmacy_env/api/server.py
ADDED
|
@@ -0,0 +1,6 @@
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 1 |
+
"""Backward-compatible app import path.
|
| 2 |
+
|
| 3 |
+
Use `polypharmacy_env.api.app:app` for the main app module.
|
| 4 |
+
"""
|
| 5 |
+
|
| 6 |
+
from .app import app
|
openenv-polypharmacy/{src β backend/src}/polypharmacy_env/baselines/__init__.py
RENAMED
|
File without changes
|
openenv-polypharmacy/{src β backend/src}/polypharmacy_env/baselines/heuristic_agent.py
RENAMED
|
File without changes
|
openenv-polypharmacy/{src β backend/src}/polypharmacy_env/baselines/random_agent.py
RENAMED
|
File without changes
|
openenv-polypharmacy/{src β backend/src}/polypharmacy_env/client.py
RENAMED
|
File without changes
|
openenv-polypharmacy/{src β backend/src}/polypharmacy_env/config.py
RENAMED
|
@@ -7,7 +7,7 @@ from pathlib import Path
|
|
| 7 |
from typing import Dict
|
| 8 |
|
| 9 |
# ββ Paths ββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββ
|
| 10 |
-
PROJECT_ROOT = Path(__file__).resolve().parents[
|
| 11 |
DATA_DIR = PROJECT_ROOT / "data"
|
| 12 |
LOOKUPS_DIR = DATA_DIR / "lookups"
|
| 13 |
PROCESSED_DIR = DATA_DIR / "processed"
|
|
|
|
| 7 |
from typing import Dict
|
| 8 |
|
| 9 |
# ββ Paths ββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββ
|
| 10 |
+
PROJECT_ROOT = Path(__file__).resolve().parents[3] # openenv-polypharmacy/
|
| 11 |
DATA_DIR = PROJECT_ROOT / "data"
|
| 12 |
LOOKUPS_DIR = DATA_DIR / "lookups"
|
| 13 |
PROCESSED_DIR = DATA_DIR / "processed"
|
openenv-polypharmacy/{src β backend/src}/polypharmacy_env/data_loader.py
RENAMED
|
File without changes
|
openenv-polypharmacy/{src β backend/src}/polypharmacy_env/ddi_simulator.py
RENAMED
|
File without changes
|
openenv-polypharmacy/{src β backend/src}/polypharmacy_env/env_core.py
RENAMED
|
File without changes
|
openenv-polypharmacy/{src β backend/src}/polypharmacy_env/graders.py
RENAMED
|
File without changes
|
openenv-polypharmacy/{src β backend/src}/polypharmacy_env/models.py
RENAMED
|
File without changes
|
openenv-polypharmacy/{src β backend/src}/polypharmacy_env/rewards.py
RENAMED
|
File without changes
|
openenv-polypharmacy/backend/src/polypharmacy_env/services/__init__.py
ADDED
|
@@ -0,0 +1 @@
|
|
|
|
|
|
|
| 1 |
+
"""Service layer for external integrations."""
|
openenv-polypharmacy/backend/src/polypharmacy_env/services/groq_agent.py
ADDED
|
@@ -0,0 +1,246 @@
|
|
|
|
|
|
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|
|
|
|
|
|
|
|
|
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|
|
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|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 1 |
+
"""Groq-powered action suggester for PolypharmacyEnv."""
|
| 2 |
+
|
| 3 |
+
from __future__ import annotations
|
| 4 |
+
|
| 5 |
+
import json
|
| 6 |
+
import os
|
| 7 |
+
from typing import Any
|
| 8 |
+
|
| 9 |
+
from openai import OpenAI
|
| 10 |
+
|
| 11 |
+
from ..models import PolypharmacyAction, PolypharmacyObservation
|
| 12 |
+
|
| 13 |
+
DEFAULT_MODEL = "llama-3.1-8b-instant"
|
| 14 |
+
FALLBACK_MODELS = [
|
| 15 |
+
"llama-3.1-8b-instant",
|
| 16 |
+
"llama-3.3-70b-versatile",
|
| 17 |
+
"gemma2-9b-it",
|
| 18 |
+
]
|
| 19 |
+
CRITICAL_DRUG_IDS = {"DRUG_WARFARIN", "DRUG_INSULIN_GLARGINE", "DRUG_DIGOXIN"}
|
| 20 |
+
|
| 21 |
+
SYSTEM_PROMPT = """You are a clinical medication safety assistant.
|
| 22 |
+
Return exactly one JSON object describing the next action.
|
| 23 |
+
Allowed output schema:
|
| 24 |
+
{
|
| 25 |
+
"action_type": "query_ddi" | "propose_intervention" | "finish_review",
|
| 26 |
+
"drug_id_1": "optional",
|
| 27 |
+
"drug_id_2": "optional",
|
| 28 |
+
"target_drug_id": "optional",
|
| 29 |
+
"intervention_type": "stop|dose_reduce|substitute|add_monitoring|none",
|
| 30 |
+
"proposed_new_drug_id": "optional",
|
| 31 |
+
"rationale": "optional"
|
| 32 |
+
}
|
| 33 |
+
No markdown fences. No extra text.
|
| 34 |
+
Do NOT use finish_review early. First, gather evidence with query_ddi and/or
|
| 35 |
+
perform at least one meaningful intervention when needed.
|
| 36 |
+
"""
|
| 37 |
+
|
| 38 |
+
|
| 39 |
+
def _obs_to_prompt(obs: PolypharmacyObservation) -> str:
|
| 40 |
+
meds = ", ".join(m.drug_id for m in obs.current_medications)
|
| 41 |
+
conds = ", ".join(obs.conditions)
|
| 42 |
+
return (
|
| 43 |
+
f"Task: {obs.task_id}\n"
|
| 44 |
+
f"Age: {obs.age}, sex: {obs.sex}\n"
|
| 45 |
+
f"Conditions: {conds}\n"
|
| 46 |
+
f"Medications: {meds}\n"
|
| 47 |
+
f"Query budget: {obs.remaining_query_budget}\n"
|
| 48 |
+
f"Intervention budget: {obs.remaining_intervention_budget}\n"
|
| 49 |
+
f"Step index: {obs.step_index}\n"
|
| 50 |
+
"Choose the single safest, most useful next action."
|
| 51 |
+
)
|
| 52 |
+
|
| 53 |
+
|
| 54 |
+
def _parse_action(text: str) -> PolypharmacyAction:
|
| 55 |
+
raw = text.strip()
|
| 56 |
+
if raw.startswith("```"):
|
| 57 |
+
raw = raw.split("\n", 1)[-1]
|
| 58 |
+
if raw.endswith("```"):
|
| 59 |
+
raw = raw.rsplit("```", 1)[0]
|
| 60 |
+
raw = raw.strip()
|
| 61 |
+
payload: dict[str, Any] = json.loads(raw)
|
| 62 |
+
return PolypharmacyAction.model_validate(payload)
|
| 63 |
+
|
| 64 |
+
|
| 65 |
+
def _fallback_query_action(obs: PolypharmacyObservation) -> PolypharmacyAction:
|
| 66 |
+
meds = [m.drug_id for m in obs.current_medications]
|
| 67 |
+
if len(meds) >= 2 and obs.remaining_query_budget > 0:
|
| 68 |
+
return PolypharmacyAction(
|
| 69 |
+
action_type="query_ddi",
|
| 70 |
+
drug_id_1=meds[0],
|
| 71 |
+
drug_id_2=meds[1],
|
| 72 |
+
)
|
| 73 |
+
return PolypharmacyAction(action_type="finish_review")
|
| 74 |
+
|
| 75 |
+
|
| 76 |
+
def _norm_pair(a: str, b: str) -> tuple[str, str]:
|
| 77 |
+
return (a, b) if a < b else (b, a)
|
| 78 |
+
|
| 79 |
+
|
| 80 |
+
def _pick_unseen_query_pair(obs: PolypharmacyObservation) -> tuple[str, str] | None:
|
| 81 |
+
meds = [m.drug_id for m in obs.current_medications]
|
| 82 |
+
if len(meds) < 2 or obs.remaining_query_budget <= 0:
|
| 83 |
+
return None
|
| 84 |
+
|
| 85 |
+
seen = {
|
| 86 |
+
_norm_pair(q.drug_id_1, q.drug_id_2)
|
| 87 |
+
for q in obs.interaction_queries
|
| 88 |
+
}
|
| 89 |
+
# Prioritize pairs containing high-risk drugs.
|
| 90 |
+
high_risk = [m.drug_id for m in obs.current_medications if m.is_high_risk_elderly]
|
| 91 |
+
ordered = high_risk + [m for m in meds if m not in set(high_risk)]
|
| 92 |
+
|
| 93 |
+
for i in range(len(ordered)):
|
| 94 |
+
for j in range(i + 1, len(ordered)):
|
| 95 |
+
p = _norm_pair(ordered[i], ordered[j])
|
| 96 |
+
if p not in seen:
|
| 97 |
+
return p
|
| 98 |
+
return None
|
| 99 |
+
|
| 100 |
+
|
| 101 |
+
def _pick_intervention_target(obs: PolypharmacyObservation) -> str | None:
|
| 102 |
+
if obs.remaining_intervention_budget <= 0:
|
| 103 |
+
return None
|
| 104 |
+
med_set = {m.drug_id for m in obs.current_medications}
|
| 105 |
+
|
| 106 |
+
# Use latest discovered severe/moderate query as intervention target.
|
| 107 |
+
for q in reversed(obs.interaction_queries):
|
| 108 |
+
if q.severity in ("severe", "moderate"):
|
| 109 |
+
m1 = next((m for m in obs.current_medications if m.drug_id == q.drug_id_1), None)
|
| 110 |
+
m2 = next((m for m in obs.current_medications if m.drug_id == q.drug_id_2), None)
|
| 111 |
+
candidates = [m for m in (m1, m2) if m is not None]
|
| 112 |
+
if not candidates:
|
| 113 |
+
continue
|
| 114 |
+
# Prefer non-critical risky drugs first.
|
| 115 |
+
candidates.sort(
|
| 116 |
+
key=lambda m: (
|
| 117 |
+
m.drug_id in CRITICAL_DRUG_IDS,
|
| 118 |
+
0 if any("avoid" in f for f in m.beers_flags) else 1,
|
| 119 |
+
0 if m.is_high_risk_elderly else 1,
|
| 120 |
+
)
|
| 121 |
+
)
|
| 122 |
+
return candidates[0].drug_id
|
| 123 |
+
|
| 124 |
+
# Fallback: if no severe/moderate discovered, still intervene on obviously
|
| 125 |
+
# risky medications (Beers/high-risk flags) when budgets permit.
|
| 126 |
+
risky = sorted(
|
| 127 |
+
obs.current_medications,
|
| 128 |
+
key=lambda m: (
|
| 129 |
+
0 if any("avoid" in f for f in m.beers_flags) else 1,
|
| 130 |
+
0 if m.is_high_risk_elderly else 1,
|
| 131 |
+
1 if m.drug_id in CRITICAL_DRUG_IDS else 0,
|
| 132 |
+
),
|
| 133 |
+
)
|
| 134 |
+
for med in risky:
|
| 135 |
+
if any("avoid" in f for f in med.beers_flags) or med.is_high_risk_elderly:
|
| 136 |
+
return med.drug_id
|
| 137 |
+
return None
|
| 138 |
+
|
| 139 |
+
|
| 140 |
+
def _rule_based_action(obs: PolypharmacyObservation) -> PolypharmacyAction | None:
|
| 141 |
+
# If we already discovered significant risk, intervene before more querying.
|
| 142 |
+
target = _pick_intervention_target(obs)
|
| 143 |
+
if target and (
|
| 144 |
+
obs.step_index >= 1
|
| 145 |
+
and (
|
| 146 |
+
obs.remaining_query_budget <= 2
|
| 147 |
+
or len(obs.interaction_queries) >= 4
|
| 148 |
+
or any(q.severity in ("severe", "moderate") for q in obs.interaction_queries)
|
| 149 |
+
)
|
| 150 |
+
):
|
| 151 |
+
intervention = "stop"
|
| 152 |
+
rationale = "Remove likely contributor to discovered interaction risk"
|
| 153 |
+
if target in CRITICAL_DRUG_IDS:
|
| 154 |
+
# Avoid blunt stop for critical meds.
|
| 155 |
+
intervention = "dose_reduce"
|
| 156 |
+
rationale = "Critical medication: prefer dose reduction over abrupt stop"
|
| 157 |
+
return PolypharmacyAction(
|
| 158 |
+
action_type="propose_intervention",
|
| 159 |
+
target_drug_id=target,
|
| 160 |
+
intervention_type=intervention,
|
| 161 |
+
rationale=rationale,
|
| 162 |
+
)
|
| 163 |
+
|
| 164 |
+
pair = _pick_unseen_query_pair(obs)
|
| 165 |
+
if pair:
|
| 166 |
+
return PolypharmacyAction(
|
| 167 |
+
action_type="query_ddi",
|
| 168 |
+
drug_id_1=pair[0],
|
| 169 |
+
drug_id_2=pair[1],
|
| 170 |
+
)
|
| 171 |
+
|
| 172 |
+
if obs.remaining_intervention_budget > 0:
|
| 173 |
+
# Final fallback before finish: at least one safety action.
|
| 174 |
+
target = _pick_intervention_target(obs)
|
| 175 |
+
if target:
|
| 176 |
+
return PolypharmacyAction(
|
| 177 |
+
action_type="propose_intervention",
|
| 178 |
+
target_drug_id=target,
|
| 179 |
+
intervention_type="dose_reduce"
|
| 180 |
+
if target in CRITICAL_DRUG_IDS
|
| 181 |
+
else "stop",
|
| 182 |
+
rationale="Fallback intervention when query options are exhausted",
|
| 183 |
+
)
|
| 184 |
+
|
| 185 |
+
if obs.step_index >= 3:
|
| 186 |
+
return PolypharmacyAction(action_type="finish_review")
|
| 187 |
+
return None
|
| 188 |
+
|
| 189 |
+
|
| 190 |
+
def _postprocess_action(
|
| 191 |
+
obs: PolypharmacyObservation, action: PolypharmacyAction
|
| 192 |
+
) -> PolypharmacyAction:
|
| 193 |
+
# First apply deterministic guardrails to avoid repetitive loops.
|
| 194 |
+
ruled = _rule_based_action(obs)
|
| 195 |
+
if ruled is not None:
|
| 196 |
+
return ruled
|
| 197 |
+
|
| 198 |
+
# Guardrail: prevent useless immediate finish actions.
|
| 199 |
+
if action.action_type == "finish_review":
|
| 200 |
+
if obs.step_index < 2 and obs.remaining_query_budget > 0:
|
| 201 |
+
return _fallback_query_action(obs)
|
| 202 |
+
if len(obs.interaction_queries) == 0 and obs.remaining_query_budget > 0:
|
| 203 |
+
return _fallback_query_action(obs)
|
| 204 |
+
return action
|
| 205 |
+
|
| 206 |
+
|
| 207 |
+
def suggest_action_from_observation(
|
| 208 |
+
observation: PolypharmacyObservation,
|
| 209 |
+
model_name: str | None = None,
|
| 210 |
+
) -> PolypharmacyAction:
|
| 211 |
+
"""Use Groq chat completions to suggest a valid action."""
|
| 212 |
+
api_key = os.getenv("GROQ_API_KEY", "").strip()
|
| 213 |
+
if not api_key:
|
| 214 |
+
raise ValueError("GROQ_API_KEY is missing. Add it to your .env file.")
|
| 215 |
+
|
| 216 |
+
base_url = os.getenv("GROQ_BASE_URL", "https://api.groq.com/openai/v1").strip()
|
| 217 |
+
model = (model_name or os.getenv("GROQ_MODEL_NAME", DEFAULT_MODEL)).strip()
|
| 218 |
+
client = OpenAI(api_key=api_key, base_url=base_url)
|
| 219 |
+
|
| 220 |
+
user_prompt = _obs_to_prompt(observation)
|
| 221 |
+
tried: list[tuple[str, str]] = []
|
| 222 |
+
candidates: list[str] = [model] + [m for m in FALLBACK_MODELS if m != model]
|
| 223 |
+
|
| 224 |
+
for candidate in candidates:
|
| 225 |
+
try:
|
| 226 |
+
resp = client.chat.completions.create(
|
| 227 |
+
model=candidate,
|
| 228 |
+
messages=[
|
| 229 |
+
{"role": "system", "content": SYSTEM_PROMPT},
|
| 230 |
+
{"role": "user", "content": user_prompt},
|
| 231 |
+
],
|
| 232 |
+
temperature=0.2,
|
| 233 |
+
max_tokens=220,
|
| 234 |
+
)
|
| 235 |
+
generated = (resp.choices[0].message.content or "").strip()
|
| 236 |
+
parsed = _parse_action(generated)
|
| 237 |
+
return _postprocess_action(observation, parsed)
|
| 238 |
+
except Exception as exc:
|
| 239 |
+
tried.append((candidate, str(exc)))
|
| 240 |
+
|
| 241 |
+
tried_txt = " | ".join(f"{m}: {err}" for m, err in tried)
|
| 242 |
+
raise ValueError(
|
| 243 |
+
"No Groq model worked. Try one of: "
|
| 244 |
+
"llama-3.3-70b-versatile, llama-3.1-8b-instant, gemma2-9b-it. "
|
| 245 |
+
f"Errors: {tried_txt}"
|
| 246 |
+
)
|
openenv-polypharmacy/{src β backend/src}/polypharmacy_env/tasks.py
RENAMED
|
File without changes
|
openenv-polypharmacy/{src β backend/src}/polypharmacy_env/tests/__init__.py
RENAMED
|
File without changes
|
openenv-polypharmacy/{src β backend/src}/polypharmacy_env/tests/test_api.py
RENAMED
|
File without changes
|
openenv-polypharmacy/{src β backend/src}/polypharmacy_env/tests/test_env_core.py
RENAMED
|
File without changes
|
openenv-polypharmacy/data/processed/patients_polypharmacy.csv
CHANGED
|
@@ -1,44 +1,44 @@
|
|
| 1 |
episode_id,age,sex,conditions,eGFR_category,liver_function_category,medication_ids,baseline_risk_score,difficulty
|
| 2 |
-
EP_0001,72,F,HTN,moderate,normal,
|
| 3 |
EP_0002,67,M,OA;COPD;neuropathy,normal,normal,DRUG_IBUPROFEN;DRUG_TRAMADOL;DRUG_AMITRIPTYLINE,0.2833,easy
|
| 4 |
-
EP_0003,73,F,HTN;HF,normal,normal,
|
| 5 |
-
EP_0004,74,M,CKD,mild,impaired,
|
| 6 |
EP_0005,76,F,OA;neuropathy;CKD,mild,normal,DRUG_IBUPROFEN;DRUG_GABAPENTIN;DRUG_TRAMADOL;DRUG_NAPROXEN;DRUG_AMITRIPTYLINE,0.17,easy
|
| 7 |
-
EP_0006,74,M,HTN;OA,normal,impaired,DRUG_IBUPROFEN;
|
| 8 |
-
EP_0007,90,M,BPH;OA,moderate,normal,
|
| 9 |
EP_0008,77,F,CKD;OA;depression,mild,normal,DRUG_AMITRIPTYLINE;DRUG_IBUPROFEN;DRUG_SERTRALINE;DRUG_TRAMADOL;DRUG_FUROSEMIDE,0.17,easy
|
| 10 |
-
EP_0009,67,M,COPD;GERD;BPH,mild,normal,
|
| 11 |
-
EP_0010,75,M,dementia;HTN;depression,normal,impaired,DRUG_TRAMADOL;
|
| 12 |
-
EP_0011,83,F,AF,moderate,normal,
|
| 13 |
-
EP_0012,71,F,HTN;GERD;depression,normal,normal,
|
| 14 |
-
EP_0013,70,F,HF;HTN;AF,mild,normal,
|
| 15 |
EP_0014,82,F,dementia,normal,normal,DRUG_DONEPEZIL;DRUG_NAPROXEN;DRUG_APIXABAN;DRUG_SPIRONOLACTONE;DRUG_FUROSEMIDE,0.17,easy
|
| 16 |
EP_0015,84,F,dementia;neuropathy,normal,normal,DRUG_DONEPEZIL;DRUG_GABAPENTIN;DRUG_AMITRIPTYLINE;DRUG_CELECOXIB;DRUG_TRAMADOL,0.17,easy
|
| 17 |
-
EP_0016,83,M,HTN,normal,normal,
|
| 18 |
-
EP_0017,83,F,CKD,severe,normal,
|
| 19 |
-
EP_0018,70,F,CKD;HF;HTN,mild,normal,DRUG_SPIRONOLACTONE;
|
| 20 |
-
EP_0019,84,M,DM;depression,normal,normal,
|
| 21 |
-
EP_0020,90,F,neuropathy;BPH;AF,normal,normal,DRUG_WARFARIN;
|
| 22 |
-
EP_0021,87,M,HTN;BPH;HF,normal,normal,
|
| 23 |
-
EP_0022,90,M,AF;GERD;DM,normal,impaired,
|
| 24 |
-
EP_0023,90,F,HF,normal,normal,
|
| 25 |
EP_0024,71,F,OA,mild,normal,DRUG_IBUPROFEN;DRUG_GABAPENTIN;DRUG_TRAMADOL;DRUG_NAPROXEN;DRUG_APIXABAN,0.17,easy
|
| 26 |
-
EP_0025,71,M,COPD;AF;neuropathy,mild,normal,
|
| 27 |
-
EP_0026,88,M,GERD;dementia,severe,normal,
|
| 28 |
EP_0027,76,M,AF,normal,normal,DRUG_DIGOXIN;DRUG_METOPROLOL;DRUG_WARFARIN;DRUG_APIXABAN;DRUG_NAPROXEN,0.43,easy
|
| 29 |
EP_0028,73,F,CKD,moderate,normal,DRUG_AMLODIPINE;DRUG_FUROSEMIDE;DRUG_METFORMIN;DRUG_AMITRIPTYLINE;DRUG_TRAMADOL,0.17,easy
|
| 30 |
-
EP_0029,70,F,CKD;OA,mild,normal,DRUG_IBUPROFEN;
|
| 31 |
-
EP_0030,87,F,dementia;HF;depression,normal,normal,
|
| 32 |
-
EP_0031,69,M,HF,severe,normal,
|
| 33 |
EP_0032,89,F,neuropathy,mild,normal,DRUG_AMITRIPTYLINE;DRUG_GABAPENTIN;DRUG_PREDNISONE;DRUG_TRAMADOL,0.2125,easy
|
| 34 |
EP_0033,68,F,dementia,mild,impaired,DRUG_DONEPEZIL;DRUG_OMEPRAZOLE;DRUG_SPIRONOLACTONE;DRUG_TRAMADOL;DRUG_ALPRAZOLAM,0.182,easy
|
| 35 |
-
EP_0034,84,F,CKD;HF;HTN,moderate,normal,
|
| 36 |
-
EP_0035,74,M,HTN;DM,normal,impaired,
|
| 37 |
-
EP_0036,80,F,DM;neuropathy;HTN,severe,normal,
|
| 38 |
-
EP_0037,78,M,HF,normal,normal,
|
| 39 |
-
EP_0038,89,F,HTN;AF,moderate,normal,
|
| 40 |
EP_0039,78,F,OA;depression,moderate,normal,DRUG_GABAPENTIN;DRUG_FLUOXETINE;DRUG_TRAMADOL;DRUG_SERTRALINE,0.205,easy
|
| 41 |
-
EP_0040,72,F,neuropathy;COPD;BPH,normal,normal,
|
| 42 |
EP_0041,89,F,AF;BPH;DM;HF;HTN,mild,normal,DRUG_GLIPIZIDE;DRUG_DIGOXIN;DRUG_METOPROLOL;DRUG_WARFARIN;DRUG_METFORMIN;DRUG_AMLODIPINE;DRUG_INSULIN_GLARGINE;DRUG_HYDROCHLOROTHIAZIDE;DRUG_APIXABAN,0.1,medium
|
| 43 |
EP_0042,66,F,HTN;AF;CKD,moderate,normal,DRUG_METOPROLOL;DRUG_AMLODIPINE;DRUG_LISINOPRIL;DRUG_DIGOXIN;DRUG_FUROSEMIDE;DRUG_WARFARIN;DRUG_APIXABAN;DRUG_HYDROCHLOROTHIAZIDE;DRUG_IBUPROFEN;DRUG_SERTRALINE,0.173,medium
|
| 44 |
EP_0043,70,F,OA;HTN;dementia,moderate,normal,DRUG_TRAMADOL;DRUG_HYDROCHLOROTHIAZIDE;DRUG_GABAPENTIN;DRUG_IBUPROFEN;DRUG_DONEPEZIL;DRUG_FUROSEMIDE;DRUG_NAPROXEN;DRUG_LISINOPRIL;DRUG_METOPROLOL,0.0467,medium
|
|
|
|
| 1 |
episode_id,age,sex,conditions,eGFR_category,liver_function_category,medication_ids,baseline_risk_score,difficulty
|
| 2 |
+
EP_0001,72,F,HTN,moderate,normal,DRUG_AMLODIPINE;DRUG_LISINOPRIL;DRUG_DIGOXIN;DRUG_FUROSEMIDE;DRUG_AMIODARONE,0.25,easy
|
| 3 |
EP_0002,67,M,OA;COPD;neuropathy,normal,normal,DRUG_IBUPROFEN;DRUG_TRAMADOL;DRUG_AMITRIPTYLINE,0.2833,easy
|
| 4 |
+
EP_0003,73,F,HTN;HF,normal,normal,DRUG_FUROSEMIDE;DRUG_FLUOXETINE;DRUG_TRAMADOL,0.2733,easy
|
| 5 |
+
EP_0004,74,M,CKD,mild,impaired,DRUG_AMITRIPTYLINE;DRUG_AMLODIPINE;DRUG_TRAMADOL,0.2833,easy
|
| 6 |
EP_0005,76,F,OA;neuropathy;CKD,mild,normal,DRUG_IBUPROFEN;DRUG_GABAPENTIN;DRUG_TRAMADOL;DRUG_NAPROXEN;DRUG_AMITRIPTYLINE,0.17,easy
|
| 7 |
+
EP_0006,74,M,HTN;OA,normal,impaired,DRUG_IBUPROFEN;DRUG_LISINOPRIL;DRUG_DIGOXIN;DRUG_FUROSEMIDE;DRUG_AMIODARONE,0.25,easy
|
| 8 |
+
EP_0007,90,M,BPH;OA,moderate,normal,DRUG_WARFARIN;DRUG_NAPROXEN;DRUG_TAMSULOSIN;DRUG_GABAPENTIN,0.225,easy
|
| 9 |
EP_0008,77,F,CKD;OA;depression,mild,normal,DRUG_AMITRIPTYLINE;DRUG_IBUPROFEN;DRUG_SERTRALINE;DRUG_TRAMADOL;DRUG_FUROSEMIDE,0.17,easy
|
| 10 |
+
EP_0009,67,M,COPD;GERD;BPH,mild,normal,DRUG_WARFARIN;DRUG_IBUPROFEN;DRUG_OMEPRAZOLE;DRUG_TAMSULOSIN,0.22,easy
|
| 11 |
+
EP_0010,75,M,dementia;HTN;depression,normal,impaired,DRUG_TRAMADOL;DRUG_SERTRALINE;DRUG_AMITRIPTYLINE,0.2833,easy
|
| 12 |
+
EP_0011,83,F,AF,moderate,normal,DRUG_ALPRAZOLAM;DRUG_WARFARIN;DRUG_DIGOXIN;DRUG_TRAMADOL,0.2275,easy
|
| 13 |
+
EP_0012,71,F,HTN;GERD;depression,normal,normal,DRUG_DIAZEPAM;DRUG_AMLODIPINE;DRUG_FLUOXETINE;DRUG_LISINOPRIL;DRUG_TRAMADOL,0.348,easy
|
| 14 |
+
EP_0013,70,F,HF;HTN;AF,mild,normal,DRUG_ALPRAZOLAM;DRUG_FUROSEMIDE;DRUG_TRAMADOL,0.3033,easy
|
| 15 |
EP_0014,82,F,dementia,normal,normal,DRUG_DONEPEZIL;DRUG_NAPROXEN;DRUG_APIXABAN;DRUG_SPIRONOLACTONE;DRUG_FUROSEMIDE,0.17,easy
|
| 16 |
EP_0015,84,F,dementia;neuropathy,normal,normal,DRUG_DONEPEZIL;DRUG_GABAPENTIN;DRUG_AMITRIPTYLINE;DRUG_CELECOXIB;DRUG_TRAMADOL,0.17,easy
|
| 17 |
+
EP_0016,83,M,HTN,normal,normal,DRUG_ALPRAZOLAM;DRUG_METOPROLOL;DRUG_TRAMADOL,0.3033,easy
|
| 18 |
+
EP_0017,83,F,CKD,severe,normal,DRUG_DIAZEPAM;DRUG_AMLODIPINE;DRUG_TRAMADOL,0.3067,easy
|
| 19 |
+
EP_0018,70,F,CKD;HF;HTN,mild,normal,DRUG_SPIRONOLACTONE;DRUG_AMLODIPINE;DRUG_ALPRAZOLAM;DRUG_METOPROLOL;DRUG_TRAMADOL,0.182,easy
|
| 20 |
+
EP_0019,84,M,DM;depression,normal,normal,DRUG_INSULIN_GLARGINE;DRUG_FLUOXETINE;DRUG_AMITRIPTYLINE;DRUG_GLIPIZIDE;DRUG_TRAMADOL,0.434,easy
|
| 21 |
+
EP_0020,90,F,neuropathy;BPH;AF,normal,normal,DRUG_WARFARIN;DRUG_DIGOXIN;DRUG_AMIODARONE;DRUG_TAMSULOSIN,0.2,easy
|
| 22 |
+
EP_0021,87,M,HTN;BPH;HF,normal,normal,DRUG_SPIRONOLACTONE;DRUG_APIXABAN;DRUG_NAPROXEN;DRUG_AMLODIPINE,0.2125,easy
|
| 23 |
+
EP_0022,90,M,AF;GERD;DM,normal,impaired,DRUG_OMEPRAZOLE;DRUG_DIAZEPAM;DRUG_METOPROLOL;DRUG_TRAMADOL,0.23,easy
|
| 24 |
+
EP_0023,90,F,HF,normal,normal,DRUG_DIAZEPAM;DRUG_METOPROLOL;DRUG_TRAMADOL,0.3067,easy
|
| 25 |
EP_0024,71,F,OA,mild,normal,DRUG_IBUPROFEN;DRUG_GABAPENTIN;DRUG_TRAMADOL;DRUG_NAPROXEN;DRUG_APIXABAN,0.17,easy
|
| 26 |
+
EP_0025,71,M,COPD;AF;neuropathy,mild,normal,DRUG_WARFARIN;DRUG_DIGOXIN;DRUG_AMIODARONE;DRUG_GABAPENTIN,0.2,easy
|
| 27 |
+
EP_0026,88,M,GERD;dementia,severe,normal,DRUG_DONEPEZIL;DRUG_OMEPRAZOLE;DRUG_APIXABAN;DRUG_NAPROXEN,0.2125,easy
|
| 28 |
EP_0027,76,M,AF,normal,normal,DRUG_DIGOXIN;DRUG_METOPROLOL;DRUG_WARFARIN;DRUG_APIXABAN;DRUG_NAPROXEN,0.43,easy
|
| 29 |
EP_0028,73,F,CKD,moderate,normal,DRUG_AMLODIPINE;DRUG_FUROSEMIDE;DRUG_METFORMIN;DRUG_AMITRIPTYLINE;DRUG_TRAMADOL,0.17,easy
|
| 30 |
+
EP_0029,70,F,CKD;OA,mild,normal,DRUG_IBUPROFEN;DRUG_AMLODIPINE;DRUG_AMITRIPTYLINE;DRUG_GABAPENTIN;DRUG_TRAMADOL,0.17,easy
|
| 31 |
+
EP_0030,87,F,dementia;HF;depression,normal,normal,DRUG_DIGOXIN;DRUG_FLUOXETINE;DRUG_DONEPEZIL;DRUG_FUROSEMIDE;DRUG_AMIODARONE,0.25,easy
|
| 32 |
+
EP_0031,69,M,HF,severe,normal,DRUG_SPIRONOLACTONE;DRUG_LISINOPRIL;DRUG_DIGOXIN;DRUG_FUROSEMIDE;DRUG_AMIODARONE,0.426,easy
|
| 33 |
EP_0032,89,F,neuropathy,mild,normal,DRUG_AMITRIPTYLINE;DRUG_GABAPENTIN;DRUG_PREDNISONE;DRUG_TRAMADOL,0.2125,easy
|
| 34 |
EP_0033,68,F,dementia,mild,impaired,DRUG_DONEPEZIL;DRUG_OMEPRAZOLE;DRUG_SPIRONOLACTONE;DRUG_TRAMADOL;DRUG_ALPRAZOLAM,0.182,easy
|
| 35 |
+
EP_0034,84,F,CKD;HF;HTN,moderate,normal,DRUG_WARFARIN;DRUG_DIGOXIN;DRUG_NAPROXEN;DRUG_HYDROCHLOROTHIAZIDE,0.225,easy
|
| 36 |
+
EP_0035,74,M,HTN;DM,normal,impaired,DRUG_FLUOXETINE;DRUG_HYDROCHLOROTHIAZIDE;DRUG_GLIPIZIDE;DRUG_METOPROLOL;DRUG_TRAMADOL,0.164,easy
|
| 37 |
+
EP_0036,80,F,DM;neuropathy;HTN,severe,normal,DRUG_DIGOXIN;DRUG_AMLODIPINE;DRUG_AMIODARONE;DRUG_AMITRIPTYLINE,0.2,easy
|
| 38 |
+
EP_0037,78,M,HF,normal,normal,DRUG_LISINOPRIL;DRUG_AMITRIPTYLINE;DRUG_FUROSEMIDE;DRUG_TRAMADOL,0.2125,easy
|
| 39 |
+
EP_0038,89,F,HTN;AF,moderate,normal,DRUG_AMITRIPTYLINE;DRUG_FUROSEMIDE;DRUG_TRAMADOL,0.2833,easy
|
| 40 |
EP_0039,78,F,OA;depression,moderate,normal,DRUG_GABAPENTIN;DRUG_FLUOXETINE;DRUG_TRAMADOL;DRUG_SERTRALINE,0.205,easy
|
| 41 |
+
EP_0040,72,F,neuropathy;COPD;BPH,normal,normal,DRUG_ALPRAZOLAM;DRUG_AMITRIPTYLINE;DRUG_TRAMADOL;DRUG_TAMSULOSIN,0.44,easy
|
| 42 |
EP_0041,89,F,AF;BPH;DM;HF;HTN,mild,normal,DRUG_GLIPIZIDE;DRUG_DIGOXIN;DRUG_METOPROLOL;DRUG_WARFARIN;DRUG_METFORMIN;DRUG_AMLODIPINE;DRUG_INSULIN_GLARGINE;DRUG_HYDROCHLOROTHIAZIDE;DRUG_APIXABAN,0.1,medium
|
| 43 |
EP_0042,66,F,HTN;AF;CKD,moderate,normal,DRUG_METOPROLOL;DRUG_AMLODIPINE;DRUG_LISINOPRIL;DRUG_DIGOXIN;DRUG_FUROSEMIDE;DRUG_WARFARIN;DRUG_APIXABAN;DRUG_HYDROCHLOROTHIAZIDE;DRUG_IBUPROFEN;DRUG_SERTRALINE,0.173,medium
|
| 44 |
EP_0043,70,F,OA;HTN;dementia,moderate,normal,DRUG_TRAMADOL;DRUG_HYDROCHLOROTHIAZIDE;DRUG_GABAPENTIN;DRUG_IBUPROFEN;DRUG_DONEPEZIL;DRUG_FUROSEMIDE;DRUG_NAPROXEN;DRUG_LISINOPRIL;DRUG_METOPROLOL,0.0467,medium
|
openenv-polypharmacy/docker-compose.yml
ADDED
|
@@ -0,0 +1,35 @@
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 1 |
+
version: "3.9"
|
| 2 |
+
|
| 3 |
+
services:
|
| 4 |
+
backend:
|
| 5 |
+
build:
|
| 6 |
+
context: .
|
| 7 |
+
dockerfile: backend/Dockerfile
|
| 8 |
+
container_name: polypharmacy-backend
|
| 9 |
+
env_file:
|
| 10 |
+
- .env
|
| 11 |
+
ports:
|
| 12 |
+
- "7860:7860"
|
| 13 |
+
volumes:
|
| 14 |
+
- ./backend/src:/app/backend/src
|
| 15 |
+
- ./data:/app/data
|
| 16 |
+
- ./scripts:/app/scripts
|
| 17 |
+
- ./backend:/app/backend
|
| 18 |
+
healthcheck:
|
| 19 |
+
test: ["CMD", "curl", "-f", "http://localhost:7860/health"]
|
| 20 |
+
interval: 20s
|
| 21 |
+
timeout: 5s
|
| 22 |
+
retries: 5
|
| 23 |
+
|
| 24 |
+
frontend:
|
| 25 |
+
build:
|
| 26 |
+
context: .
|
| 27 |
+
dockerfile: frontend/Dockerfile
|
| 28 |
+
container_name: polypharmacy-frontend
|
| 29 |
+
depends_on:
|
| 30 |
+
- backend
|
| 31 |
+
ports:
|
| 32 |
+
- "5173:5173"
|
| 33 |
+
volumes:
|
| 34 |
+
- ./frontend:/app
|
| 35 |
+
- /app/node_modules
|
openenv-polypharmacy/frontend/Dockerfile
ADDED
|
@@ -0,0 +1,12 @@
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 1 |
+
FROM node:20-alpine
|
| 2 |
+
|
| 3 |
+
WORKDIR /app
|
| 4 |
+
|
| 5 |
+
COPY frontend/package*.json ./
|
| 6 |
+
RUN npm ci
|
| 7 |
+
|
| 8 |
+
COPY frontend/ ./
|
| 9 |
+
|
| 10 |
+
EXPOSE 5173
|
| 11 |
+
|
| 12 |
+
CMD ["npm", "run", "dev", "--", "--host", "0.0.0.0", "--port", "5173"]
|
openenv-polypharmacy/frontend/index.html
ADDED
|
@@ -0,0 +1,12 @@
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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| 1 |
+
<!doctype html>
|
| 2 |
+
<html lang="en">
|
| 3 |
+
<head>
|
| 4 |
+
<meta charset="UTF-8" />
|
| 5 |
+
<meta name="viewport" content="width=device-width, initial-scale=1.0" />
|
| 6 |
+
<title>Polypharmacy Control Center</title>
|
| 7 |
+
</head>
|
| 8 |
+
<body>
|
| 9 |
+
<div id="root"></div>
|
| 10 |
+
<script type="module" src="/src/main.jsx"></script>
|
| 11 |
+
</body>
|
| 12 |
+
</html>
|
openenv-polypharmacy/frontend/package-lock.json
ADDED
|
@@ -0,0 +1,1677 @@
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|
|
| 1 |
+
{
|
| 2 |
+
"name": "polypharmacy-frontend",
|
| 3 |
+
"version": "0.1.0",
|
| 4 |
+
"lockfileVersion": 3,
|
| 5 |
+
"requires": true,
|
| 6 |
+
"packages": {
|
| 7 |
+
"": {
|
| 8 |
+
"name": "polypharmacy-frontend",
|
| 9 |
+
"version": "0.1.0",
|
| 10 |
+
"dependencies": {
|
| 11 |
+
"react": "^18.3.1",
|
| 12 |
+
"react-dom": "^18.3.1"
|
| 13 |
+
},
|
| 14 |
+
"devDependencies": {
|
| 15 |
+
"@vitejs/plugin-react": "^4.3.1",
|
| 16 |
+
"vite": "^5.4.2"
|
| 17 |
+
}
|
| 18 |
+
},
|
| 19 |
+
"node_modules/@babel/code-frame": {
|
| 20 |
+
"version": "7.29.0",
|
| 21 |
+
"resolved": "https://registry.npmjs.org/@babel/code-frame/-/code-frame-7.29.0.tgz",
|
| 22 |
+
"integrity": "sha512-9NhCeYjq9+3uxgdtp20LSiJXJvN0FeCtNGpJxuMFZ1Kv3cWUNb6DOhJwUvcVCzKGR66cw4njwM6hrJLqgOwbcw==",
|
| 23 |
+
"dev": true,
|
| 24 |
+
"license": "MIT",
|
| 25 |
+
"dependencies": {
|
| 26 |
+
"@babel/helper-validator-identifier": "^7.28.5",
|
| 27 |
+
"js-tokens": "^4.0.0",
|
| 28 |
+
"picocolors": "^1.1.1"
|
| 29 |
+
},
|
| 30 |
+
"engines": {
|
| 31 |
+
"node": ">=6.9.0"
|
| 32 |
+
}
|
| 33 |
+
},
|
| 34 |
+
"node_modules/@babel/compat-data": {
|
| 35 |
+
"version": "7.29.0",
|
| 36 |
+
"resolved": "https://registry.npmjs.org/@babel/compat-data/-/compat-data-7.29.0.tgz",
|
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"node_modules/source-map-js": {
|
| 1569 |
+
"version": "1.2.1",
|
| 1570 |
+
"resolved": "https://registry.npmjs.org/source-map-js/-/source-map-js-1.2.1.tgz",
|
| 1571 |
+
"integrity": "sha512-UXWMKhLOwVKb728IUtQPXxfYU+usdybtUrK/8uGE8CQMvrhOpwvzDBwj0QhSL7MQc7vIsISBG8VQ8+IDQxpfQA==",
|
| 1572 |
+
"dev": true,
|
| 1573 |
+
"license": "BSD-3-Clause",
|
| 1574 |
+
"engines": {
|
| 1575 |
+
"node": ">=0.10.0"
|
| 1576 |
+
}
|
| 1577 |
+
},
|
| 1578 |
+
"node_modules/update-browserslist-db": {
|
| 1579 |
+
"version": "1.2.3",
|
| 1580 |
+
"resolved": "https://registry.npmjs.org/update-browserslist-db/-/update-browserslist-db-1.2.3.tgz",
|
| 1581 |
+
"integrity": "sha512-Js0m9cx+qOgDxo0eMiFGEueWztz+d4+M3rGlmKPT+T4IS/jP4ylw3Nwpu6cpTTP8R1MAC1kF4VbdLt3ARf209w==",
|
| 1582 |
+
"dev": true,
|
| 1583 |
+
"funding": [
|
| 1584 |
+
{
|
| 1585 |
+
"type": "opencollective",
|
| 1586 |
+
"url": "https://opencollective.com/browserslist"
|
| 1587 |
+
},
|
| 1588 |
+
{
|
| 1589 |
+
"type": "tidelift",
|
| 1590 |
+
"url": "https://tidelift.com/funding/github/npm/browserslist"
|
| 1591 |
+
},
|
| 1592 |
+
{
|
| 1593 |
+
"type": "github",
|
| 1594 |
+
"url": "https://github.com/sponsors/ai"
|
| 1595 |
+
}
|
| 1596 |
+
],
|
| 1597 |
+
"license": "MIT",
|
| 1598 |
+
"dependencies": {
|
| 1599 |
+
"escalade": "^3.2.0",
|
| 1600 |
+
"picocolors": "^1.1.1"
|
| 1601 |
+
},
|
| 1602 |
+
"bin": {
|
| 1603 |
+
"update-browserslist-db": "cli.js"
|
| 1604 |
+
},
|
| 1605 |
+
"peerDependencies": {
|
| 1606 |
+
"browserslist": ">= 4.21.0"
|
| 1607 |
+
}
|
| 1608 |
+
},
|
| 1609 |
+
"node_modules/vite": {
|
| 1610 |
+
"version": "5.4.21",
|
| 1611 |
+
"resolved": "https://registry.npmjs.org/vite/-/vite-5.4.21.tgz",
|
| 1612 |
+
"integrity": "sha512-o5a9xKjbtuhY6Bi5S3+HvbRERmouabWbyUcpXXUA1u+GNUKoROi9byOJ8M0nHbHYHkYICiMlqxkg1KkYmm25Sw==",
|
| 1613 |
+
"dev": true,
|
| 1614 |
+
"license": "MIT",
|
| 1615 |
+
"dependencies": {
|
| 1616 |
+
"esbuild": "^0.21.3",
|
| 1617 |
+
"postcss": "^8.4.43",
|
| 1618 |
+
"rollup": "^4.20.0"
|
| 1619 |
+
},
|
| 1620 |
+
"bin": {
|
| 1621 |
+
"vite": "bin/vite.js"
|
| 1622 |
+
},
|
| 1623 |
+
"engines": {
|
| 1624 |
+
"node": "^18.0.0 || >=20.0.0"
|
| 1625 |
+
},
|
| 1626 |
+
"funding": {
|
| 1627 |
+
"url": "https://github.com/vitejs/vite?sponsor=1"
|
| 1628 |
+
},
|
| 1629 |
+
"optionalDependencies": {
|
| 1630 |
+
"fsevents": "~2.3.3"
|
| 1631 |
+
},
|
| 1632 |
+
"peerDependencies": {
|
| 1633 |
+
"@types/node": "^18.0.0 || >=20.0.0",
|
| 1634 |
+
"less": "*",
|
| 1635 |
+
"lightningcss": "^1.21.0",
|
| 1636 |
+
"sass": "*",
|
| 1637 |
+
"sass-embedded": "*",
|
| 1638 |
+
"stylus": "*",
|
| 1639 |
+
"sugarss": "*",
|
| 1640 |
+
"terser": "^5.4.0"
|
| 1641 |
+
},
|
| 1642 |
+
"peerDependenciesMeta": {
|
| 1643 |
+
"@types/node": {
|
| 1644 |
+
"optional": true
|
| 1645 |
+
},
|
| 1646 |
+
"less": {
|
| 1647 |
+
"optional": true
|
| 1648 |
+
},
|
| 1649 |
+
"lightningcss": {
|
| 1650 |
+
"optional": true
|
| 1651 |
+
},
|
| 1652 |
+
"sass": {
|
| 1653 |
+
"optional": true
|
| 1654 |
+
},
|
| 1655 |
+
"sass-embedded": {
|
| 1656 |
+
"optional": true
|
| 1657 |
+
},
|
| 1658 |
+
"stylus": {
|
| 1659 |
+
"optional": true
|
| 1660 |
+
},
|
| 1661 |
+
"sugarss": {
|
| 1662 |
+
"optional": true
|
| 1663 |
+
},
|
| 1664 |
+
"terser": {
|
| 1665 |
+
"optional": true
|
| 1666 |
+
}
|
| 1667 |
+
}
|
| 1668 |
+
},
|
| 1669 |
+
"node_modules/yallist": {
|
| 1670 |
+
"version": "3.1.1",
|
| 1671 |
+
"resolved": "https://registry.npmjs.org/yallist/-/yallist-3.1.1.tgz",
|
| 1672 |
+
"integrity": "sha512-a4UGQaWPH59mOXUYnAG2ewncQS4i4F43Tv3JoAM+s2VDAmS9NsK8GpDMLrCHPksFT7h3K6TOoUNn2pb7RoXx4g==",
|
| 1673 |
+
"dev": true,
|
| 1674 |
+
"license": "ISC"
|
| 1675 |
+
}
|
| 1676 |
+
}
|
| 1677 |
+
}
|
openenv-polypharmacy/frontend/package.json
ADDED
|
@@ -0,0 +1,19 @@
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 1 |
+
{
|
| 2 |
+
"name": "polypharmacy-frontend",
|
| 3 |
+
"version": "0.1.0",
|
| 4 |
+
"private": true,
|
| 5 |
+
"type": "module",
|
| 6 |
+
"scripts": {
|
| 7 |
+
"dev": "vite",
|
| 8 |
+
"build": "vite build",
|
| 9 |
+
"preview": "vite preview --port 4173"
|
| 10 |
+
},
|
| 11 |
+
"dependencies": {
|
| 12 |
+
"react": "^18.3.1",
|
| 13 |
+
"react-dom": "^18.3.1"
|
| 14 |
+
},
|
| 15 |
+
"devDependencies": {
|
| 16 |
+
"@vitejs/plugin-react": "^4.3.1",
|
| 17 |
+
"vite": "^5.4.2"
|
| 18 |
+
}
|
| 19 |
+
}
|
openenv-polypharmacy/frontend/src/App.jsx
ADDED
|
@@ -0,0 +1,371 @@
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
|
|
|
|
|
|
|
|
|
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|
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|
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|
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 1 |
+
import { useEffect, useMemo, useRef, useState } from "react";
|
| 2 |
+
|
| 3 |
+
const API_BASE = "http://localhost:7860";
|
| 4 |
+
const WS_URL = "ws://localhost:7860/ws";
|
| 5 |
+
const TASKS = ["easy_screening", "budgeted_screening", "complex_tradeoff"];
|
| 6 |
+
|
| 7 |
+
async function apiPost(path, body) {
|
| 8 |
+
const res = await fetch(`${API_BASE}${path}`, {
|
| 9 |
+
method: "POST",
|
| 10 |
+
headers: { "Content-Type": "application/json" },
|
| 11 |
+
body: JSON.stringify(body),
|
| 12 |
+
});
|
| 13 |
+
if (!res.ok) {
|
| 14 |
+
const msg = await res.text();
|
| 15 |
+
throw new Error(msg || `HTTP ${res.status}`);
|
| 16 |
+
}
|
| 17 |
+
return res.json();
|
| 18 |
+
}
|
| 19 |
+
|
| 20 |
+
export default function App() {
|
| 21 |
+
const [taskId, setTaskId] = useState("budgeted_screening");
|
| 22 |
+
const [obs, setObs] = useState(null);
|
| 23 |
+
const [log, setLog] = useState([]);
|
| 24 |
+
const [loading, setLoading] = useState(false);
|
| 25 |
+
const [action, setAction] = useState({
|
| 26 |
+
action_type: "query_ddi",
|
| 27 |
+
drug_id_1: "",
|
| 28 |
+
drug_id_2: "",
|
| 29 |
+
target_drug_id: "",
|
| 30 |
+
intervention_type: "stop",
|
| 31 |
+
proposed_new_drug_id: "",
|
| 32 |
+
rationale: "",
|
| 33 |
+
});
|
| 34 |
+
|
| 35 |
+
const medIds = useMemo(
|
| 36 |
+
() => (obs?.current_medications || []).map((m) => m.drug_id),
|
| 37 |
+
[obs]
|
| 38 |
+
);
|
| 39 |
+
const hasValidEpisode = Boolean(obs?.episode_id) && (obs?.current_medications?.length || 0) > 0;
|
| 40 |
+
const isDone = Boolean(obs?.done);
|
| 41 |
+
const finalScore =
|
| 42 |
+
typeof obs?.metadata?.grader_score === "number" ? obs.metadata.grader_score : null;
|
| 43 |
+
const noBudgetsLeft =
|
| 44 |
+
hasValidEpisode &&
|
| 45 |
+
(obs?.remaining_query_budget ?? 0) <= 0 &&
|
| 46 |
+
(obs?.remaining_intervention_budget ?? 0) <= 0;
|
| 47 |
+
const wsRef = useRef(null);
|
| 48 |
+
const pendingRef = useRef([]);
|
| 49 |
+
|
| 50 |
+
const wsEnsure = async () => {
|
| 51 |
+
if (wsRef.current && wsRef.current.readyState === WebSocket.OPEN) return wsRef.current;
|
| 52 |
+
if (wsRef.current && wsRef.current.readyState === WebSocket.CONNECTING) {
|
| 53 |
+
await new Promise((r) => setTimeout(r, 80));
|
| 54 |
+
return wsEnsure();
|
| 55 |
+
}
|
| 56 |
+
|
| 57 |
+
const ws = new WebSocket(WS_URL);
|
| 58 |
+
wsRef.current = ws;
|
| 59 |
+
|
| 60 |
+
ws.onmessage = (evt) => {
|
| 61 |
+
try {
|
| 62 |
+
const msg = JSON.parse(evt.data);
|
| 63 |
+
const pending = pendingRef.current.shift();
|
| 64 |
+
if (pending) pending.resolve(msg);
|
| 65 |
+
} catch (e) {
|
| 66 |
+
const pending = pendingRef.current.shift();
|
| 67 |
+
if (pending) pending.reject(e);
|
| 68 |
+
}
|
| 69 |
+
};
|
| 70 |
+
ws.onerror = (err) => {
|
| 71 |
+
const pending = pendingRef.current.shift();
|
| 72 |
+
if (pending) pending.reject(err);
|
| 73 |
+
};
|
| 74 |
+
ws.onclose = () => {
|
| 75 |
+
wsRef.current = null;
|
| 76 |
+
};
|
| 77 |
+
|
| 78 |
+
await new Promise((resolve, reject) => {
|
| 79 |
+
const t = setTimeout(() => reject(new Error("WebSocket connect timeout")), 2500);
|
| 80 |
+
ws.onopen = () => {
|
| 81 |
+
clearTimeout(t);
|
| 82 |
+
resolve();
|
| 83 |
+
};
|
| 84 |
+
});
|
| 85 |
+
return ws;
|
| 86 |
+
};
|
| 87 |
+
|
| 88 |
+
const wsSend = async (type, data) => {
|
| 89 |
+
const ws = await wsEnsure();
|
| 90 |
+
return await new Promise((resolve, reject) => {
|
| 91 |
+
pendingRef.current.push({ resolve, reject });
|
| 92 |
+
ws.send(JSON.stringify({ type, data }));
|
| 93 |
+
});
|
| 94 |
+
};
|
| 95 |
+
|
| 96 |
+
useEffect(() => {
|
| 97 |
+
return () => {
|
| 98 |
+
try {
|
| 99 |
+
wsRef.current?.close();
|
| 100 |
+
} catch {
|
| 101 |
+
// ignore
|
| 102 |
+
}
|
| 103 |
+
};
|
| 104 |
+
}, []);
|
| 105 |
+
|
| 106 |
+
const appendLog = (text) => {
|
| 107 |
+
setLog((prev) => [`${new Date().toLocaleTimeString()} ${text}`, ...prev].slice(0, 20));
|
| 108 |
+
};
|
| 109 |
+
|
| 110 |
+
const normalizeObsFromWs = (packetData) => {
|
| 111 |
+
const observation = packetData?.observation || {};
|
| 112 |
+
const mergedMetadata = {
|
| 113 |
+
...(observation?.metadata || {}),
|
| 114 |
+
...(packetData?.info || {}),
|
| 115 |
+
};
|
| 116 |
+
return {
|
| 117 |
+
...observation,
|
| 118 |
+
done: Boolean(packetData?.done ?? observation?.done ?? false),
|
| 119 |
+
reward: packetData?.reward ?? observation?.reward ?? null,
|
| 120 |
+
metadata: mergedMetadata,
|
| 121 |
+
};
|
| 122 |
+
};
|
| 123 |
+
|
| 124 |
+
const handleReset = async () => {
|
| 125 |
+
setLoading(true);
|
| 126 |
+
try {
|
| 127 |
+
const msg = await wsSend("reset", { task_id: taskId });
|
| 128 |
+
const data = msg?.data || {};
|
| 129 |
+
const normalized = normalizeObsFromWs(data);
|
| 130 |
+
setObs(normalized);
|
| 131 |
+
const ids = (normalized?.current_medications || []).map((m) => m.drug_id);
|
| 132 |
+
setAction((prev) => ({
|
| 133 |
+
...prev,
|
| 134 |
+
drug_id_1: ids[0] || "",
|
| 135 |
+
drug_id_2: ids[1] || "",
|
| 136 |
+
target_drug_id: ids[0] || "",
|
| 137 |
+
}));
|
| 138 |
+
appendLog(`Reset task=${taskId}`);
|
| 139 |
+
} catch (err) {
|
| 140 |
+
appendLog(`Reset failed: ${err.message}`);
|
| 141 |
+
} finally {
|
| 142 |
+
setLoading(false);
|
| 143 |
+
}
|
| 144 |
+
};
|
| 145 |
+
|
| 146 |
+
const buildActionPayload = () => {
|
| 147 |
+
if (noBudgetsLeft) {
|
| 148 |
+
return { action_type: "finish_review" };
|
| 149 |
+
}
|
| 150 |
+
if (action.action_type === "query_ddi") {
|
| 151 |
+
return {
|
| 152 |
+
action_type: "query_ddi",
|
| 153 |
+
drug_id_1: action.drug_id_1,
|
| 154 |
+
drug_id_2: action.drug_id_2,
|
| 155 |
+
};
|
| 156 |
+
}
|
| 157 |
+
if (action.action_type === "propose_intervention") {
|
| 158 |
+
return {
|
| 159 |
+
action_type: "propose_intervention",
|
| 160 |
+
target_drug_id: action.target_drug_id,
|
| 161 |
+
intervention_type: action.intervention_type,
|
| 162 |
+
proposed_new_drug_id: action.proposed_new_drug_id || undefined,
|
| 163 |
+
rationale: action.rationale || undefined,
|
| 164 |
+
};
|
| 165 |
+
}
|
| 166 |
+
return { action_type: "finish_review" };
|
| 167 |
+
};
|
| 168 |
+
|
| 169 |
+
const isActionValid = () => {
|
| 170 |
+
if (!hasValidEpisode) return false;
|
| 171 |
+
if (isDone) return false;
|
| 172 |
+
if (noBudgetsLeft) return true;
|
| 173 |
+
if (action.action_type === "query_ddi") {
|
| 174 |
+
return Boolean(action.drug_id_1 && action.drug_id_2);
|
| 175 |
+
}
|
| 176 |
+
if (action.action_type === "propose_intervention") {
|
| 177 |
+
return Boolean(action.target_drug_id && action.intervention_type);
|
| 178 |
+
}
|
| 179 |
+
return true;
|
| 180 |
+
};
|
| 181 |
+
|
| 182 |
+
const handleStep = async (overrideAction = null) => {
|
| 183 |
+
if (!hasValidEpisode) {
|
| 184 |
+
appendLog("Run Reset Episode before stepping.");
|
| 185 |
+
return;
|
| 186 |
+
}
|
| 187 |
+
setLoading(true);
|
| 188 |
+
try {
|
| 189 |
+
const payload = overrideAction || buildActionPayload();
|
| 190 |
+
const msg = await wsSend("step", payload);
|
| 191 |
+
const data = msg?.data || {};
|
| 192 |
+
const normalized = normalizeObsFromWs(data);
|
| 193 |
+
setObs(normalized);
|
| 194 |
+
appendLog(`Step: ${payload.action_type} -> reward=${data.reward ?? 0}`);
|
| 195 |
+
} catch (err) {
|
| 196 |
+
appendLog(`Step failed: ${err.message}`);
|
| 197 |
+
} finally {
|
| 198 |
+
setLoading(false);
|
| 199 |
+
}
|
| 200 |
+
};
|
| 201 |
+
|
| 202 |
+
const askAi = async () => {
|
| 203 |
+
if (!hasValidEpisode) {
|
| 204 |
+
appendLog("Run Reset Episode before asking AI.");
|
| 205 |
+
return;
|
| 206 |
+
}
|
| 207 |
+
setLoading(true);
|
| 208 |
+
try {
|
| 209 |
+
const data = await apiPost("/agent/suggest", { observation: obs });
|
| 210 |
+
appendLog(`AI suggestion: ${data.action.action_type}`);
|
| 211 |
+
await handleStep(data.action);
|
| 212 |
+
} catch (err) {
|
| 213 |
+
appendLog(`AI suggestion failed: ${err.message}`);
|
| 214 |
+
} finally {
|
| 215 |
+
setLoading(false);
|
| 216 |
+
}
|
| 217 |
+
};
|
| 218 |
+
|
| 219 |
+
return (
|
| 220 |
+
<div className="shell">
|
| 221 |
+
<div className="bg-orb orb-a" />
|
| 222 |
+
<div className="bg-orb orb-b" />
|
| 223 |
+
|
| 224 |
+
<div className="container">
|
| 225 |
+
<header className="topbar glass">
|
| 226 |
+
<div className="title-wrap">
|
| 227 |
+
<h1>Polypharmacy Control Center</h1>
|
| 228 |
+
</div>
|
| 229 |
+
<div className={`status-chip ${hasValidEpisode ? "live" : "idle"}`}>
|
| 230 |
+
{hasValidEpisode ? "Session Live" : "Waiting for reset"}
|
| 231 |
+
</div>
|
| 232 |
+
<div className="actions">
|
| 233 |
+
<select value={taskId} onChange={(e) => setTaskId(e.target.value)}>
|
| 234 |
+
{TASKS.map((t) => (
|
| 235 |
+
<option key={t} value={t}>
|
| 236 |
+
{t}
|
| 237 |
+
</option>
|
| 238 |
+
))}
|
| 239 |
+
</select>
|
| 240 |
+
<button onClick={handleReset} disabled={loading}>
|
| 241 |
+
Reset Episode
|
| 242 |
+
</button>
|
| 243 |
+
<button className="secondary" onClick={askAi} disabled={!hasValidEpisode || isDone || loading}>
|
| 244 |
+
Ask AI + Auto Step
|
| 245 |
+
</button>
|
| 246 |
+
</div>
|
| 247 |
+
</header>
|
| 248 |
+
|
| 249 |
+
<main className="layout">
|
| 250 |
+
<section className="panel glass panel-wide">
|
| 251 |
+
<h2>Episode</h2>
|
| 252 |
+
{hasValidEpisode ? (
|
| 253 |
+
<div className="kpi-grid">
|
| 254 |
+
<div><span>Episode</span><strong>{obs.episode_id}</strong></div>
|
| 255 |
+
<div><span>Task</span><strong>{obs.task_id}</strong></div>
|
| 256 |
+
<div><span>Age / Sex</span><strong>{obs.age} / {obs.sex}</strong></div>
|
| 257 |
+
<div><span>Step</span><strong>{obs.step_index}</strong></div>
|
| 258 |
+
<div><span>Query budget</span><strong>{obs.remaining_query_budget}</strong></div>
|
| 259 |
+
<div><span>Intervention budget</span><strong>{obs.remaining_intervention_budget}</strong></div>
|
| 260 |
+
</div>
|
| 261 |
+
) : (
|
| 262 |
+
<p className="muted">Start with Reset Episode. Until then, step actions are blocked.</p>
|
| 263 |
+
)}
|
| 264 |
+
{noBudgetsLeft && (
|
| 265 |
+
<p className="muted budget-note">Query and intervention budgets are exhausted. Finish review to get final score.</p>
|
| 266 |
+
)}
|
| 267 |
+
{isDone && (
|
| 268 |
+
<p className="muted budget-note">
|
| 269 |
+
Episode complete
|
| 270 |
+
{finalScore !== null ? ` β’ final score: ${finalScore.toFixed(3)}` : ""}.
|
| 271 |
+
Click Reset Episode to start a new case.
|
| 272 |
+
</p>
|
| 273 |
+
)}
|
| 274 |
+
</section>
|
| 275 |
+
|
| 276 |
+
<section className="panel glass">
|
| 277 |
+
<h2>Action Console</h2>
|
| 278 |
+
<div className="action-row">
|
| 279 |
+
<label>Action type</label>
|
| 280 |
+
<select
|
| 281 |
+
value={action.action_type}
|
| 282 |
+
onChange={(e) => setAction((a) => ({ ...a, action_type: e.target.value }))}
|
| 283 |
+
>
|
| 284 |
+
<option value="query_ddi">query_ddi</option>
|
| 285 |
+
<option value="propose_intervention">propose_intervention</option>
|
| 286 |
+
<option value="finish_review">finish_review</option>
|
| 287 |
+
</select>
|
| 288 |
+
</div>
|
| 289 |
+
|
| 290 |
+
{action.action_type === "query_ddi" && (
|
| 291 |
+
<div className="stack stack-two">
|
| 292 |
+
<input
|
| 293 |
+
placeholder="drug_id_1"
|
| 294 |
+
value={action.drug_id_1}
|
| 295 |
+
onChange={(e) => setAction((a) => ({ ...a, drug_id_1: e.target.value }))}
|
| 296 |
+
/>
|
| 297 |
+
<input
|
| 298 |
+
placeholder="drug_id_2"
|
| 299 |
+
value={action.drug_id_2}
|
| 300 |
+
onChange={(e) => setAction((a) => ({ ...a, drug_id_2: e.target.value }))}
|
| 301 |
+
/>
|
| 302 |
+
</div>
|
| 303 |
+
)}
|
| 304 |
+
|
| 305 |
+
{action.action_type === "propose_intervention" && (
|
| 306 |
+
<div className="stack">
|
| 307 |
+
<select
|
| 308 |
+
value={action.target_drug_id}
|
| 309 |
+
onChange={(e) => setAction((a) => ({ ...a, target_drug_id: e.target.value }))}
|
| 310 |
+
>
|
| 311 |
+
<option value="">Select target drug</option>
|
| 312 |
+
{medIds.map((id) => (
|
| 313 |
+
<option key={id} value={id}>
|
| 314 |
+
{id}
|
| 315 |
+
</option>
|
| 316 |
+
))}
|
| 317 |
+
</select>
|
| 318 |
+
<select
|
| 319 |
+
value={action.intervention_type}
|
| 320 |
+
onChange={(e) => setAction((a) => ({ ...a, intervention_type: e.target.value }))}
|
| 321 |
+
>
|
| 322 |
+
<option value="stop">stop</option>
|
| 323 |
+
<option value="dose_reduce">dose_reduce</option>
|
| 324 |
+
<option value="substitute">substitute</option>
|
| 325 |
+
<option value="add_monitoring">add_monitoring</option>
|
| 326 |
+
</select>
|
| 327 |
+
<input
|
| 328 |
+
placeholder="proposed_new_drug_id (optional)"
|
| 329 |
+
value={action.proposed_new_drug_id}
|
| 330 |
+
onChange={(e) =>
|
| 331 |
+
setAction((a) => ({ ...a, proposed_new_drug_id: e.target.value }))
|
| 332 |
+
}
|
| 333 |
+
/>
|
| 334 |
+
<input
|
| 335 |
+
placeholder="rationale (optional)"
|
| 336 |
+
value={action.rationale}
|
| 337 |
+
onChange={(e) => setAction((a) => ({ ...a, rationale: e.target.value }))}
|
| 338 |
+
/>
|
| 339 |
+
</div>
|
| 340 |
+
)}
|
| 341 |
+
<button onClick={() => handleStep()} disabled={!isActionValid() || loading}>
|
| 342 |
+
{noBudgetsLeft ? "Finish Review" : "Submit Step"}
|
| 343 |
+
</button>
|
| 344 |
+
</section>
|
| 345 |
+
|
| 346 |
+
<section className="panel glass">
|
| 347 |
+
<h2>Current Medications</h2>
|
| 348 |
+
<div className="med-grid">
|
| 349 |
+
{(obs?.current_medications || []).map((m) => (
|
| 350 |
+
<div key={m.drug_id} className="med-card">
|
| 351 |
+
<strong>{m.drug_id}</strong>
|
| 352 |
+
<p>{m.generic_name}</p>
|
| 353 |
+
<small>{m.dose_mg} mg β’ {m.atc_class}</small>
|
| 354 |
+
</div>
|
| 355 |
+
))}
|
| 356 |
+
</div>
|
| 357 |
+
</section>
|
| 358 |
+
|
| 359 |
+
<section className="panel glass">
|
| 360 |
+
<h2>Event Log</h2>
|
| 361 |
+
<div className="logs">
|
| 362 |
+
{log.map((line, idx) => (
|
| 363 |
+
<div key={idx}>{line}</div>
|
| 364 |
+
))}
|
| 365 |
+
</div>
|
| 366 |
+
</section>
|
| 367 |
+
</main>
|
| 368 |
+
</div>
|
| 369 |
+
</div>
|
| 370 |
+
);
|
| 371 |
+
}
|
openenv-polypharmacy/frontend/src/main.jsx
ADDED
|
@@ -0,0 +1,10 @@
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 1 |
+
import React from "react";
|
| 2 |
+
import ReactDOM from "react-dom/client";
|
| 3 |
+
import App from "./App";
|
| 4 |
+
import "./styles.css";
|
| 5 |
+
|
| 6 |
+
ReactDOM.createRoot(document.getElementById("root")).render(
|
| 7 |
+
<React.StrictMode>
|
| 8 |
+
<App />
|
| 9 |
+
</React.StrictMode>
|
| 10 |
+
);
|
openenv-polypharmacy/frontend/src/styles.css
ADDED
|
@@ -0,0 +1,304 @@
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 1 |
+
:root {
|
| 2 |
+
--bg: #eef5ff;
|
| 3 |
+
--panel: rgba(255, 255, 255, 0.82);
|
| 4 |
+
--panel-solid: #ffffff;
|
| 5 |
+
--text: #0b2445;
|
| 6 |
+
--muted: #5b7596;
|
| 7 |
+
--primary: #1f8bff;
|
| 8 |
+
--primary-2: #69beff;
|
| 9 |
+
--accent: #0dd3ff;
|
| 10 |
+
--border: rgba(93, 156, 219, 0.22);
|
| 11 |
+
--shadow: 0 20px 50px rgba(25, 83, 143, 0.12);
|
| 12 |
+
--shadow-strong: 0 20px 42px rgba(31, 112, 182, 0.24);
|
| 13 |
+
}
|
| 14 |
+
|
| 15 |
+
* {
|
| 16 |
+
box-sizing: border-box;
|
| 17 |
+
}
|
| 18 |
+
|
| 19 |
+
body {
|
| 20 |
+
margin: 0;
|
| 21 |
+
font-family: "Inter", "SF Pro Text", "Segoe UI", sans-serif;
|
| 22 |
+
background:
|
| 23 |
+
radial-gradient(circle at 8% 0%, #cce7ff 0%, rgba(204, 231, 255, 0) 42%),
|
| 24 |
+
radial-gradient(circle at 92% 100%, #d5efff 0%, rgba(213, 239, 255, 0) 42%),
|
| 25 |
+
var(--bg);
|
| 26 |
+
color: var(--text);
|
| 27 |
+
}
|
| 28 |
+
|
| 29 |
+
.shell {
|
| 30 |
+
min-height: 100vh;
|
| 31 |
+
position: relative;
|
| 32 |
+
padding: 28px 22px;
|
| 33 |
+
overflow: hidden;
|
| 34 |
+
}
|
| 35 |
+
|
| 36 |
+
.container {
|
| 37 |
+
width: min(1300px, 100%);
|
| 38 |
+
margin: 0 auto;
|
| 39 |
+
position: relative;
|
| 40 |
+
z-index: 1;
|
| 41 |
+
}
|
| 42 |
+
|
| 43 |
+
.bg-orb {
|
| 44 |
+
position: absolute;
|
| 45 |
+
border-radius: 50%;
|
| 46 |
+
filter: blur(18px);
|
| 47 |
+
opacity: 0.9;
|
| 48 |
+
}
|
| 49 |
+
.orb-a {
|
| 50 |
+
width: 420px;
|
| 51 |
+
height: 420px;
|
| 52 |
+
right: -120px;
|
| 53 |
+
top: -100px;
|
| 54 |
+
background: radial-gradient(circle, rgba(72, 168, 255, 0.5), rgba(72, 168, 255, 0.1));
|
| 55 |
+
}
|
| 56 |
+
.orb-b {
|
| 57 |
+
width: 360px;
|
| 58 |
+
height: 360px;
|
| 59 |
+
left: -100px;
|
| 60 |
+
bottom: -120px;
|
| 61 |
+
background: radial-gradient(circle, rgba(110, 200, 255, 0.4), rgba(141, 205, 255, 0.06));
|
| 62 |
+
}
|
| 63 |
+
|
| 64 |
+
.glass {
|
| 65 |
+
backdrop-filter: blur(12px);
|
| 66 |
+
border: 1px solid var(--border);
|
| 67 |
+
background: var(--panel);
|
| 68 |
+
box-shadow: var(--shadow);
|
| 69 |
+
}
|
| 70 |
+
|
| 71 |
+
.topbar {
|
| 72 |
+
border-radius: 20px;
|
| 73 |
+
padding: 18px;
|
| 74 |
+
display: grid;
|
| 75 |
+
grid-template-columns: 1.2fr auto 1fr;
|
| 76 |
+
justify-content: space-between;
|
| 77 |
+
align-items: center;
|
| 78 |
+
gap: 12px;
|
| 79 |
+
}
|
| 80 |
+
|
| 81 |
+
.title-wrap h1 {
|
| 82 |
+
margin: 0;
|
| 83 |
+
font-size: clamp(1.1rem, 1.5vw, 1.45rem);
|
| 84 |
+
letter-spacing: 0.01em;
|
| 85 |
+
}
|
| 86 |
+
|
| 87 |
+
.title-wrap p {
|
| 88 |
+
margin: 4px 0 0;
|
| 89 |
+
color: var(--muted);
|
| 90 |
+
font-size: 0.92rem;
|
| 91 |
+
}
|
| 92 |
+
|
| 93 |
+
.status-chip {
|
| 94 |
+
justify-self: center;
|
| 95 |
+
border-radius: 999px;
|
| 96 |
+
padding: 7px 12px;
|
| 97 |
+
font-size: 0.76rem;
|
| 98 |
+
font-weight: 700;
|
| 99 |
+
letter-spacing: 0.04em;
|
| 100 |
+
text-transform: uppercase;
|
| 101 |
+
border: 1px solid transparent;
|
| 102 |
+
}
|
| 103 |
+
|
| 104 |
+
.status-chip.live {
|
| 105 |
+
color: #0d6a3f;
|
| 106 |
+
background: rgba(130, 245, 195, 0.18);
|
| 107 |
+
border-color: rgba(70, 199, 142, 0.3);
|
| 108 |
+
}
|
| 109 |
+
|
| 110 |
+
.status-chip.idle {
|
| 111 |
+
color: #24527f;
|
| 112 |
+
background: rgba(114, 194, 255, 0.18);
|
| 113 |
+
border-color: rgba(62, 152, 223, 0.28);
|
| 114 |
+
}
|
| 115 |
+
|
| 116 |
+
.actions {
|
| 117 |
+
display: flex;
|
| 118 |
+
justify-content: flex-end;
|
| 119 |
+
gap: 10px;
|
| 120 |
+
flex-wrap: wrap;
|
| 121 |
+
}
|
| 122 |
+
|
| 123 |
+
button,
|
| 124 |
+
select,
|
| 125 |
+
input {
|
| 126 |
+
border: 1px solid var(--border);
|
| 127 |
+
border-radius: 12px;
|
| 128 |
+
padding: 10px 13px;
|
| 129 |
+
font-size: 0.92rem;
|
| 130 |
+
background: #fff;
|
| 131 |
+
color: var(--text);
|
| 132 |
+
min-height: 42px;
|
| 133 |
+
}
|
| 134 |
+
|
| 135 |
+
button {
|
| 136 |
+
cursor: pointer;
|
| 137 |
+
background: linear-gradient(135deg, var(--primary) 0%, var(--primary-2) 78%, var(--accent) 100%);
|
| 138 |
+
color: #fff;
|
| 139 |
+
border: none;
|
| 140 |
+
font-weight: 700;
|
| 141 |
+
box-shadow: var(--shadow-strong);
|
| 142 |
+
transition: transform 120ms ease, filter 120ms ease;
|
| 143 |
+
}
|
| 144 |
+
|
| 145 |
+
button:hover {
|
| 146 |
+
transform: translateY(-1px);
|
| 147 |
+
filter: brightness(1.02);
|
| 148 |
+
}
|
| 149 |
+
|
| 150 |
+
button.secondary {
|
| 151 |
+
background: linear-gradient(135deg, #68c2ff, #9dd9ff);
|
| 152 |
+
}
|
| 153 |
+
|
| 154 |
+
button:disabled {
|
| 155 |
+
opacity: 0.58;
|
| 156 |
+
cursor: not-allowed;
|
| 157 |
+
transform: none;
|
| 158 |
+
}
|
| 159 |
+
|
| 160 |
+
.layout {
|
| 161 |
+
margin-top: 18px;
|
| 162 |
+
display: grid;
|
| 163 |
+
gap: 16px;
|
| 164 |
+
grid-template-columns: 1.15fr 0.85fr;
|
| 165 |
+
align-items: start;
|
| 166 |
+
}
|
| 167 |
+
|
| 168 |
+
.panel {
|
| 169 |
+
border-radius: 18px;
|
| 170 |
+
padding: 18px;
|
| 171 |
+
}
|
| 172 |
+
|
| 173 |
+
.panel-wide {
|
| 174 |
+
grid-column: 1 / -1;
|
| 175 |
+
}
|
| 176 |
+
|
| 177 |
+
.panel h2 {
|
| 178 |
+
margin: 0 0 12px;
|
| 179 |
+
font-size: 1rem;
|
| 180 |
+
letter-spacing: 0.01em;
|
| 181 |
+
}
|
| 182 |
+
|
| 183 |
+
.kpi-grid {
|
| 184 |
+
display: grid;
|
| 185 |
+
grid-template-columns: repeat(3, minmax(0, 1fr));
|
| 186 |
+
gap: 12px;
|
| 187 |
+
}
|
| 188 |
+
|
| 189 |
+
.kpi-grid div {
|
| 190 |
+
background: rgba(255, 255, 255, 0.9);
|
| 191 |
+
border: 1px solid var(--border);
|
| 192 |
+
border-radius: 14px;
|
| 193 |
+
padding: 12px;
|
| 194 |
+
}
|
| 195 |
+
|
| 196 |
+
.kpi-grid span {
|
| 197 |
+
display: block;
|
| 198 |
+
font-size: 0.74rem;
|
| 199 |
+
color: var(--muted);
|
| 200 |
+
margin-bottom: 4px;
|
| 201 |
+
}
|
| 202 |
+
|
| 203 |
+
.kpi-grid strong {
|
| 204 |
+
font-size: 1.05rem;
|
| 205 |
+
}
|
| 206 |
+
|
| 207 |
+
.action-row,
|
| 208 |
+
.stack {
|
| 209 |
+
display: grid;
|
| 210 |
+
gap: 10px;
|
| 211 |
+
margin-bottom: 12px;
|
| 212 |
+
}
|
| 213 |
+
|
| 214 |
+
.stack-two {
|
| 215 |
+
grid-template-columns: repeat(2, minmax(0, 1fr));
|
| 216 |
+
}
|
| 217 |
+
|
| 218 |
+
.med-grid {
|
| 219 |
+
display: grid;
|
| 220 |
+
grid-template-columns: repeat(3, minmax(0, 1fr));
|
| 221 |
+
gap: 10px;
|
| 222 |
+
max-height: 420px;
|
| 223 |
+
overflow: auto;
|
| 224 |
+
padding-right: 2px;
|
| 225 |
+
}
|
| 226 |
+
|
| 227 |
+
.med-card {
|
| 228 |
+
border: 1px solid var(--border);
|
| 229 |
+
border-radius: 14px;
|
| 230 |
+
padding: 12px;
|
| 231 |
+
background: var(--panel-solid);
|
| 232 |
+
transition: transform 120ms ease, box-shadow 120ms ease;
|
| 233 |
+
}
|
| 234 |
+
|
| 235 |
+
.med-card:hover {
|
| 236 |
+
transform: translateY(-1px);
|
| 237 |
+
box-shadow: 0 10px 25px rgba(44, 105, 165, 0.12);
|
| 238 |
+
}
|
| 239 |
+
|
| 240 |
+
.med-card p {
|
| 241 |
+
margin: 6px 0 4px;
|
| 242 |
+
color: var(--muted);
|
| 243 |
+
text-transform: capitalize;
|
| 244 |
+
}
|
| 245 |
+
|
| 246 |
+
.logs {
|
| 247 |
+
font-family: ui-monospace, SFMono-Regular, Menlo, Monaco, monospace;
|
| 248 |
+
font-size: 0.85rem;
|
| 249 |
+
max-height: 300px;
|
| 250 |
+
overflow: auto;
|
| 251 |
+
display: grid;
|
| 252 |
+
gap: 6px;
|
| 253 |
+
padding-right: 2px;
|
| 254 |
+
}
|
| 255 |
+
|
| 256 |
+
.logs div {
|
| 257 |
+
background: rgba(255, 255, 255, 0.78);
|
| 258 |
+
border: 1px solid var(--border);
|
| 259 |
+
border-radius: 10px;
|
| 260 |
+
padding: 8px 10px;
|
| 261 |
+
}
|
| 262 |
+
|
| 263 |
+
.muted {
|
| 264 |
+
color: var(--muted);
|
| 265 |
+
margin: 0;
|
| 266 |
+
}
|
| 267 |
+
|
| 268 |
+
.budget-note {
|
| 269 |
+
margin-top: 10px;
|
| 270 |
+
padding: 10px 12px;
|
| 271 |
+
border: 1px solid var(--border);
|
| 272 |
+
border-radius: 12px;
|
| 273 |
+
background: rgba(255, 255, 255, 0.78);
|
| 274 |
+
}
|
| 275 |
+
|
| 276 |
+
@media (max-width: 1120px) {
|
| 277 |
+
.layout {
|
| 278 |
+
grid-template-columns: 1fr;
|
| 279 |
+
}
|
| 280 |
+
|
| 281 |
+
.topbar {
|
| 282 |
+
grid-template-columns: 1fr;
|
| 283 |
+
}
|
| 284 |
+
|
| 285 |
+
.status-chip {
|
| 286 |
+
justify-self: start;
|
| 287 |
+
}
|
| 288 |
+
|
| 289 |
+
.actions {
|
| 290 |
+
justify-content: flex-start;
|
| 291 |
+
}
|
| 292 |
+
}
|
| 293 |
+
|
| 294 |
+
@media (max-width: 760px) {
|
| 295 |
+
.shell {
|
| 296 |
+
padding: 18px 12px;
|
| 297 |
+
}
|
| 298 |
+
|
| 299 |
+
.kpi-grid,
|
| 300 |
+
.med-grid,
|
| 301 |
+
.stack-two {
|
| 302 |
+
grid-template-columns: 1fr;
|
| 303 |
+
}
|
| 304 |
+
}
|
openenv-polypharmacy/frontend/vite.config.js
ADDED
|
@@ -0,0 +1,10 @@
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 1 |
+
import { defineConfig } from "vite";
|
| 2 |
+
import react from "@vitejs/plugin-react";
|
| 3 |
+
|
| 4 |
+
export default defineConfig({
|
| 5 |
+
plugins: [react()],
|
| 6 |
+
server: {
|
| 7 |
+
port: 5173,
|
| 8 |
+
host: "0.0.0.0",
|
| 9 |
+
},
|
| 10 |
+
});
|
openenv-polypharmacy/inference.py
CHANGED
|
@@ -1,15 +1,14 @@
|
|
| 1 |
#!/usr/bin/env python3
|
| 2 |
"""Baseline LLM inference script for the PolypharmacyEnv.
|
| 3 |
|
| 4 |
-
Uses
|
| 5 |
PolypharmacyEnv HTTP API. Emits structured stdout logs in the
|
| 6 |
[START], [STEP], [END] format required by the OpenEnv evaluation spec.
|
| 7 |
|
| 8 |
Environment variables:
|
| 9 |
-
|
| 10 |
-
|
| 11 |
-
|
| 12 |
-
HF_TOKEN β HuggingFace token (optional)
|
| 13 |
POLYPHARMACY_ENV_URL β environment HTTP base URL (default: http://localhost:7860)
|
| 14 |
"""
|
| 15 |
|
|
@@ -18,7 +17,6 @@ from __future__ import annotations
|
|
| 18 |
import json
|
| 19 |
import os
|
| 20 |
import sys
|
| 21 |
-
import time
|
| 22 |
import uuid
|
| 23 |
from typing import Any, Dict, List
|
| 24 |
|
|
@@ -27,10 +25,9 @@ from openai import OpenAI
|
|
| 27 |
|
| 28 |
# ββ Configuration ββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββ
|
| 29 |
|
| 30 |
-
|
| 31 |
-
|
| 32 |
-
|
| 33 |
-
HF_TOKEN = os.environ.get("HF_TOKEN", "")
|
| 34 |
ENV_URL = os.environ.get("POLYPHARMACY_ENV_URL", "http://localhost:7860")
|
| 35 |
|
| 36 |
TASKS = ["easy_screening", "budgeted_screening", "complex_tradeoff"]
|
|
@@ -119,16 +116,16 @@ def _summarise_obs(obs: Dict[str, Any]) -> str:
|
|
| 119 |
def _ask_llm(obs_summary: str) -> Dict[str, Any]:
|
| 120 |
"""Call the LLM and parse a PolypharmacyAction JSON."""
|
| 121 |
try:
|
| 122 |
-
|
| 123 |
model=MODEL,
|
| 124 |
messages=[
|
| 125 |
{"role": "system", "content": SYSTEM_PROMPT},
|
| 126 |
{"role": "user", "content": obs_summary},
|
| 127 |
],
|
| 128 |
-
temperature=0.2,
|
| 129 |
max_tokens=256,
|
|
|
|
| 130 |
)
|
| 131 |
-
text =
|
| 132 |
# Strip markdown fences if present
|
| 133 |
text = text.strip()
|
| 134 |
if text.startswith("```"):
|
|
@@ -146,7 +143,7 @@ def _ask_llm(obs_summary: str) -> Dict[str, Any]:
|
|
| 146 |
|
| 147 |
def main() -> None:
|
| 148 |
if not API_KEY:
|
| 149 |
-
_err("
|
| 150 |
sys.exit(1)
|
| 151 |
|
| 152 |
run_id = str(uuid.uuid4())[:8]
|
|
@@ -159,7 +156,6 @@ def main() -> None:
|
|
| 159 |
"run_id": run_id,
|
| 160 |
"task_id": task_id,
|
| 161 |
"model": MODEL,
|
| 162 |
-
"api_base": API_BASE,
|
| 163 |
"episodes": EPISODES_PER_TASK,
|
| 164 |
})
|
| 165 |
|
|
|
|
| 1 |
#!/usr/bin/env python3
|
| 2 |
"""Baseline LLM inference script for the PolypharmacyEnv.
|
| 3 |
|
| 4 |
+
Uses Groq's OpenAI-compatible Chat Completions API to drive an LLM agent through the
|
| 5 |
PolypharmacyEnv HTTP API. Emits structured stdout logs in the
|
| 6 |
[START], [STEP], [END] format required by the OpenEnv evaluation spec.
|
| 7 |
|
| 8 |
Environment variables:
|
| 9 |
+
GROQ_API_KEY β required
|
| 10 |
+
GROQ_BASE_URL β optional (default: https://api.groq.com/openai/v1)
|
| 11 |
+
GROQ_MODEL_NAME β model to use (default: llama-3.1-8b-instant)
|
|
|
|
| 12 |
POLYPHARMACY_ENV_URL β environment HTTP base URL (default: http://localhost:7860)
|
| 13 |
"""
|
| 14 |
|
|
|
|
| 17 |
import json
|
| 18 |
import os
|
| 19 |
import sys
|
|
|
|
| 20 |
import uuid
|
| 21 |
from typing import Any, Dict, List
|
| 22 |
|
|
|
|
| 25 |
|
| 26 |
# ββ Configuration ββββββββββββββββββββββββββββββββββββββββββββββββββββββββββββ
|
| 27 |
|
| 28 |
+
MODEL = os.environ.get("GROQ_MODEL_NAME", "llama-3.1-8b-instant")
|
| 29 |
+
API_KEY = os.environ.get("GROQ_API_KEY", "")
|
| 30 |
+
API_BASE = os.environ.get("GROQ_BASE_URL", "https://api.groq.com/openai/v1")
|
|
|
|
| 31 |
ENV_URL = os.environ.get("POLYPHARMACY_ENV_URL", "http://localhost:7860")
|
| 32 |
|
| 33 |
TASKS = ["easy_screening", "budgeted_screening", "complex_tradeoff"]
|
|
|
|
| 116 |
def _ask_llm(obs_summary: str) -> Dict[str, Any]:
|
| 117 |
"""Call the LLM and parse a PolypharmacyAction JSON."""
|
| 118 |
try:
|
| 119 |
+
chat_resp = client.chat.completions.create(
|
| 120 |
model=MODEL,
|
| 121 |
messages=[
|
| 122 |
{"role": "system", "content": SYSTEM_PROMPT},
|
| 123 |
{"role": "user", "content": obs_summary},
|
| 124 |
],
|
|
|
|
| 125 |
max_tokens=256,
|
| 126 |
+
temperature=0.2,
|
| 127 |
)
|
| 128 |
+
text = (chat_resp.choices[0].message.content or "").strip()
|
| 129 |
# Strip markdown fences if present
|
| 130 |
text = text.strip()
|
| 131 |
if text.startswith("```"):
|
|
|
|
| 143 |
|
| 144 |
def main() -> None:
|
| 145 |
if not API_KEY:
|
| 146 |
+
_err("GROQ_API_KEY is required")
|
| 147 |
sys.exit(1)
|
| 148 |
|
| 149 |
run_id = str(uuid.uuid4())[:8]
|
|
|
|
| 156 |
"run_id": run_id,
|
| 157 |
"task_id": task_id,
|
| 158 |
"model": MODEL,
|
|
|
|
| 159 |
"episodes": EPISODES_PER_TASK,
|
| 160 |
})
|
| 161 |
|
openenv-polypharmacy/openenv.yaml
CHANGED
|
@@ -13,7 +13,7 @@ tags:
|
|
| 13 |
- openenv
|
| 14 |
type: space
|
| 15 |
runtime: fastapi
|
| 16 |
-
app:
|
| 17 |
port: 7860
|
| 18 |
|
| 19 |
tasks:
|
|
|
|
| 13 |
- openenv
|
| 14 |
type: space
|
| 15 |
runtime: fastapi
|
| 16 |
+
app: backend.main:app
|
| 17 |
port: 7860
|
| 18 |
|
| 19 |
tasks:
|
openenv-polypharmacy/pyproject.toml
CHANGED
|
@@ -13,6 +13,7 @@ dependencies = [
|
|
| 13 |
"pydantic>=2.0.0",
|
| 14 |
"requests>=2.31.0",
|
| 15 |
"openai>=1.0.0",
|
|
|
|
| 16 |
"openenv-core>=0.2.0",
|
| 17 |
]
|
| 18 |
|
|
@@ -25,11 +26,11 @@ dev = [
|
|
| 25 |
]
|
| 26 |
|
| 27 |
[tool.setuptools.packages.find]
|
| 28 |
-
where = ["src"]
|
| 29 |
|
| 30 |
[tool.pytest.ini_options]
|
| 31 |
-
testpaths = ["src/polypharmacy_env/tests"]
|
| 32 |
-
pythonpath = ["src"]
|
| 33 |
|
| 34 |
[tool.black]
|
| 35 |
line-length = 99
|
|
|
|
| 13 |
"pydantic>=2.0.0",
|
| 14 |
"requests>=2.31.0",
|
| 15 |
"openai>=1.0.0",
|
| 16 |
+
"python-dotenv>=1.0.0",
|
| 17 |
"openenv-core>=0.2.0",
|
| 18 |
]
|
| 19 |
|
|
|
|
| 26 |
]
|
| 27 |
|
| 28 |
[tool.setuptools.packages.find]
|
| 29 |
+
where = ["backend/src"]
|
| 30 |
|
| 31 |
[tool.pytest.ini_options]
|
| 32 |
+
testpaths = ["backend/src/polypharmacy_env/tests"]
|
| 33 |
+
pythonpath = ["backend/src"]
|
| 34 |
|
| 35 |
[tool.black]
|
| 36 |
line-length = 99
|
openenv-polypharmacy/requirements.txt
CHANGED
|
@@ -1,8 +1 @@
|
|
| 1 |
-
|
| 2 |
-
uvicorn>=0.24.0
|
| 3 |
-
pydantic>=2.0.0
|
| 4 |
-
requests>=2.31.0
|
| 5 |
-
openai>=1.0.0
|
| 6 |
-
httpx>=0.25.0
|
| 7 |
-
openenv-core>=0.2.0
|
| 8 |
-
pytest>=7.0.0
|
|
|
|
| 1 |
+
-r backend/requirements.txt
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
openenv-polypharmacy/scripts/dev_backend.sh
ADDED
|
@@ -0,0 +1,4 @@
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 1 |
+
#!/usr/bin/env bash
|
| 2 |
+
set -euo pipefail
|
| 3 |
+
|
| 4 |
+
uvicorn backend.main:app --reload --host 0.0.0.0 --port 7860
|
openenv-polypharmacy/scripts/dev_frontend.sh
ADDED
|
@@ -0,0 +1,5 @@
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 1 |
+
#!/usr/bin/env bash
|
| 2 |
+
set -euo pipefail
|
| 3 |
+
|
| 4 |
+
cd frontend
|
| 5 |
+
npm run dev
|
openenv-polypharmacy/scripts/inference.py
DELETED
|
@@ -1,217 +0,0 @@
|
|
| 1 |
-
#!/usr/bin/env python3
|
| 2 |
-
"""LLM-based inference agent for PolypharmacyEnv.
|
| 3 |
-
|
| 4 |
-
Connects to a running OpenEnv server via WebSocket (using PolypharmacyClient)
|
| 5 |
-
and runs an LLM agent that reviews a patient's medication regimen.
|
| 6 |
-
|
| 7 |
-
Usage:
|
| 8 |
-
# Start server first:
|
| 9 |
-
# uvicorn polypharmacy_env.api.server:app --port 7860
|
| 10 |
-
|
| 11 |
-
# Then run inference:
|
| 12 |
-
python scripts/inference.py --task easy_screening --seed 42
|
| 13 |
-
python scripts/inference.py --task budgeted_screening --model gpt-4o
|
| 14 |
-
"""
|
| 15 |
-
|
| 16 |
-
from __future__ import annotations
|
| 17 |
-
|
| 18 |
-
import argparse
|
| 19 |
-
import asyncio
|
| 20 |
-
import json
|
| 21 |
-
import os
|
| 22 |
-
import sys
|
| 23 |
-
from typing import Any, Dict, List
|
| 24 |
-
|
| 25 |
-
# Add src to path
|
| 26 |
-
sys.path.insert(0, os.path.join(os.path.dirname(__file__), "..", "src"))
|
| 27 |
-
|
| 28 |
-
from polypharmacy_env.client import PolypharmacyClient
|
| 29 |
-
from polypharmacy_env.models import PolypharmacyAction, PolypharmacyObservation
|
| 30 |
-
|
| 31 |
-
try:
|
| 32 |
-
from openai import OpenAI
|
| 33 |
-
except ImportError:
|
| 34 |
-
OpenAI = None # type: ignore[assignment, misc]
|
| 35 |
-
|
| 36 |
-
|
| 37 |
-
def format_observation_for_llm(obs: PolypharmacyObservation) -> str:
|
| 38 |
-
"""Convert an observation to a human-readable prompt for the LLM."""
|
| 39 |
-
lines = [
|
| 40 |
-
f"Patient: {obs.age}yo {obs.sex}",
|
| 41 |
-
f"Conditions: {', '.join(obs.conditions)}",
|
| 42 |
-
f"eGFR: {obs.eGFR_category}, Liver: {obs.liver_function_category}",
|
| 43 |
-
f"Step: {obs.step_index}",
|
| 44 |
-
f"Query budget remaining: {obs.remaining_query_budget}",
|
| 45 |
-
f"Intervention budget remaining: {obs.remaining_intervention_budget}",
|
| 46 |
-
"",
|
| 47 |
-
"Current Medications:",
|
| 48 |
-
]
|
| 49 |
-
for med in obs.current_medications:
|
| 50 |
-
flags = f" [BEERS: {', '.join(med.beers_flags)}]" if med.beers_flags else ""
|
| 51 |
-
high_risk = " [HIGH RISK ELDERLY]" if med.is_high_risk_elderly else ""
|
| 52 |
-
lines.append(
|
| 53 |
-
f" - {med.drug_id} ({med.generic_name}) {med.atc_class} "
|
| 54 |
-
f"{med.dose_mg}mg{high_risk}{flags}"
|
| 55 |
-
)
|
| 56 |
-
|
| 57 |
-
if obs.interaction_queries:
|
| 58 |
-
lines.append("")
|
| 59 |
-
lines.append("DDI Queries So Far:")
|
| 60 |
-
for q in obs.interaction_queries:
|
| 61 |
-
lines.append(
|
| 62 |
-
f" - {q.drug_id_1} + {q.drug_id_2}: "
|
| 63 |
-
f"severity={q.severity}, rec={q.recommendation}"
|
| 64 |
-
)
|
| 65 |
-
|
| 66 |
-
if obs.interventions:
|
| 67 |
-
lines.append("")
|
| 68 |
-
lines.append("Interventions So Far:")
|
| 69 |
-
for iv in obs.interventions:
|
| 70 |
-
lines.append(f" - {iv.action_type} {iv.target_drug_id}: {iv.rationale}")
|
| 71 |
-
|
| 72 |
-
return "\n".join(lines)
|
| 73 |
-
|
| 74 |
-
|
| 75 |
-
SYSTEM_PROMPT = """\
|
| 76 |
-
You are a clinical pharmacist assistant reviewing an elderly patient's medication regimen.
|
| 77 |
-
|
| 78 |
-
Your goal: identify dangerous drug-drug interactions and Beers Criteria violations,
|
| 79 |
-
then propose safe interventions (stop, dose_reduce, substitute, add_monitoring) to
|
| 80 |
-
reduce risk while preserving therapeutic coverage.
|
| 81 |
-
|
| 82 |
-
Available actions (respond with JSON):
|
| 83 |
-
1. {"action_type": "query_ddi", "drug_id_1": "...", "drug_id_2": "..."}
|
| 84 |
-
- Check for a drug-drug interaction between two medications.
|
| 85 |
-
2. {"action_type": "propose_intervention", "target_drug_id": "...", \
|
| 86 |
-
"intervention_type": "stop|dose_reduce|substitute|add_monitoring", "rationale": "..."}
|
| 87 |
-
- Propose a change to the regimen.
|
| 88 |
-
3. {"action_type": "finish_review"}
|
| 89 |
-
- End the review and submit your final regimen.
|
| 90 |
-
|
| 91 |
-
Strategy tips:
|
| 92 |
-
- Query high-risk drug pairs first (especially those flagged as high-risk elderly or Beers).
|
| 93 |
-
- Prioritise resolving severe DDIs over moderate ones.
|
| 94 |
-
- Prefer substitution over stopping when possible.
|
| 95 |
-
- Always provide a clinical rationale for interventions.
|
| 96 |
-
- Finish the review when you've addressed all major issues or exhausted your budget.
|
| 97 |
-
|
| 98 |
-
Respond with ONLY a valid JSON action object, no explanation outside the JSON.\
|
| 99 |
-
"""
|
| 100 |
-
|
| 101 |
-
|
| 102 |
-
def parse_llm_action(text: str) -> PolypharmacyAction:
|
| 103 |
-
"""Parse an LLM response into a PolypharmacyAction."""
|
| 104 |
-
text = text.strip()
|
| 105 |
-
# Extract JSON from markdown code blocks if present
|
| 106 |
-
if "```" in text:
|
| 107 |
-
parts = text.split("```")
|
| 108 |
-
for part in parts:
|
| 109 |
-
part = part.strip()
|
| 110 |
-
if part.startswith("json"):
|
| 111 |
-
part = part[4:].strip()
|
| 112 |
-
if part.startswith("{"):
|
| 113 |
-
text = part
|
| 114 |
-
break
|
| 115 |
-
|
| 116 |
-
data = json.loads(text)
|
| 117 |
-
return PolypharmacyAction(**data)
|
| 118 |
-
|
| 119 |
-
|
| 120 |
-
async def run_llm_episode(
|
| 121 |
-
base_url: str,
|
| 122 |
-
task_id: str,
|
| 123 |
-
seed: int,
|
| 124 |
-
model: str,
|
| 125 |
-
max_retries: int = 3,
|
| 126 |
-
) -> Dict[str, Any]:
|
| 127 |
-
"""Run a single episode with LLM agent via WebSocket."""
|
| 128 |
-
if OpenAI is None:
|
| 129 |
-
raise ImportError("openai package is required. Install with: pip install openai")
|
| 130 |
-
|
| 131 |
-
llm = OpenAI()
|
| 132 |
-
total_reward = 0.0
|
| 133 |
-
steps = 0
|
| 134 |
-
messages: List[Dict[str, str]] = [{"role": "system", "content": SYSTEM_PROMPT}]
|
| 135 |
-
|
| 136 |
-
async with PolypharmacyClient(base_url=base_url) as client:
|
| 137 |
-
result = await client.reset(task_id=task_id, seed=seed)
|
| 138 |
-
obs = result.observation
|
| 139 |
-
|
| 140 |
-
while not result.done:
|
| 141 |
-
obs_text = format_observation_for_llm(obs)
|
| 142 |
-
messages.append({"role": "user", "content": obs_text})
|
| 143 |
-
|
| 144 |
-
# Call LLM
|
| 145 |
-
action = None
|
| 146 |
-
for attempt in range(max_retries):
|
| 147 |
-
try:
|
| 148 |
-
response = llm.chat.completions.create(
|
| 149 |
-
model=model,
|
| 150 |
-
messages=messages,
|
| 151 |
-
temperature=0.0,
|
| 152 |
-
max_tokens=256,
|
| 153 |
-
)
|
| 154 |
-
llm_text = response.choices[0].message.content or ""
|
| 155 |
-
messages.append({"role": "assistant", "content": llm_text})
|
| 156 |
-
action = parse_llm_action(llm_text)
|
| 157 |
-
break
|
| 158 |
-
except (json.JSONDecodeError, Exception) as e:
|
| 159 |
-
if attempt == max_retries - 1:
|
| 160 |
-
print(f" LLM parse failed after {max_retries} attempts: {e}")
|
| 161 |
-
action = PolypharmacyAction(action_type="finish_review")
|
| 162 |
-
else:
|
| 163 |
-
messages.append({
|
| 164 |
-
"role": "user",
|
| 165 |
-
"content": f"Invalid JSON. Please respond with only a valid JSON action. Error: {e}",
|
| 166 |
-
})
|
| 167 |
-
|
| 168 |
-
assert action is not None
|
| 169 |
-
result = await client.step(action)
|
| 170 |
-
obs = result.observation
|
| 171 |
-
total_reward += result.reward or 0.0
|
| 172 |
-
steps += 1
|
| 173 |
-
|
| 174 |
-
print(
|
| 175 |
-
f" step={steps} action={action.action_type} "
|
| 176 |
-
f"reward={result.reward:.4f} done={result.done}"
|
| 177 |
-
)
|
| 178 |
-
|
| 179 |
-
return {
|
| 180 |
-
"task_id": task_id,
|
| 181 |
-
"seed": seed,
|
| 182 |
-
"total_reward": total_reward,
|
| 183 |
-
"steps": steps,
|
| 184 |
-
}
|
| 185 |
-
|
| 186 |
-
|
| 187 |
-
async def amain(args: argparse.Namespace) -> None:
|
| 188 |
-
results = []
|
| 189 |
-
for seed in range(args.seed, args.seed + args.episodes):
|
| 190 |
-
print(f"\n=== Episode: task={args.task} seed={seed} ===")
|
| 191 |
-
result = await run_llm_episode(
|
| 192 |
-
base_url=args.url,
|
| 193 |
-
task_id=args.task,
|
| 194 |
-
seed=seed,
|
| 195 |
-
model=args.model,
|
| 196 |
-
)
|
| 197 |
-
results.append(result)
|
| 198 |
-
print(f" => reward={result['total_reward']:.4f} steps={result['steps']}")
|
| 199 |
-
|
| 200 |
-
if results:
|
| 201 |
-
avg_reward = sum(r["total_reward"] for r in results) / len(results)
|
| 202 |
-
print(f"\nAverage reward over {len(results)} episodes: {avg_reward:.4f}")
|
| 203 |
-
|
| 204 |
-
|
| 205 |
-
def main() -> None:
|
| 206 |
-
parser = argparse.ArgumentParser(description="Run LLM agent on PolypharmacyEnv")
|
| 207 |
-
parser.add_argument("--url", default="ws://localhost:7860", help="Server URL")
|
| 208 |
-
parser.add_argument("--task", default="budgeted_screening", help="Task ID")
|
| 209 |
-
parser.add_argument("--seed", type=int, default=0, help="Starting seed")
|
| 210 |
-
parser.add_argument("--episodes", type=int, default=1, help="Number of episodes")
|
| 211 |
-
parser.add_argument("--model", default="gpt-4o", help="LLM model name")
|
| 212 |
-
args = parser.parse_args()
|
| 213 |
-
asyncio.run(amain(args))
|
| 214 |
-
|
| 215 |
-
|
| 216 |
-
if __name__ == "__main__":
|
| 217 |
-
main()
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
openenv-polypharmacy/scripts/run_validation.sh
CHANGED
|
@@ -5,11 +5,11 @@ set -euo pipefail
|
|
| 5 |
cd "$(dirname "$0")/.."
|
| 6 |
|
| 7 |
echo "=== Running unit tests ==="
|
| 8 |
-
PYTHONPATH=src python3 -m pytest src/polypharmacy_env/tests/ -v
|
| 9 |
|
| 10 |
echo ""
|
| 11 |
echo "=== Running heuristic baseline ==="
|
| 12 |
-
PYTHONPATH=src python3 -m polypharmacy_env.baselines.heuristic_agent
|
| 13 |
|
| 14 |
echo ""
|
| 15 |
echo "=== Validation complete ==="
|
|
|
|
| 5 |
cd "$(dirname "$0")/.."
|
| 6 |
|
| 7 |
echo "=== Running unit tests ==="
|
| 8 |
+
PYTHONPATH=backend/src python3 -m pytest backend/src/polypharmacy_env/tests/ -v
|
| 9 |
|
| 10 |
echo ""
|
| 11 |
echo "=== Running heuristic baseline ==="
|
| 12 |
+
PYTHONPATH=backend/src python3 -m polypharmacy_env.baselines.heuristic_agent
|
| 13 |
|
| 14 |
echo ""
|
| 15 |
echo "=== Validation complete ==="
|