| { |
| "drug_classes": { |
| "warfarin_like": "anticoagulant", |
| "benzodiazepine_like": "sedative", |
| "metformin_like": "glucose_lowering", |
| "statin_like": "lipid_lowering", |
| "ace_inhibitor_like": "antihypertensive", |
| "nsaid_like": "analgesic", |
| "opioid_like": "analgesic", |
| "ssri_like": "antidepressant", |
| "ppi_like": "gastro", |
| "beta_blocker_like": "antihypertensive" |
| }, |
| "example_top_pairs": [ |
| [ |
| "warfarin_like", |
| "nsaid_like" |
| ], |
| [ |
| "benzodiazepine_like", |
| "opioid_like" |
| ] |
| ], |
| "side_effect_tags": { |
| "benzodiazepine_like": [ |
| "sedation", |
| "falls" |
| ], |
| "opioid_like": [ |
| "respiratory_depression", |
| "sedation" |
| ], |
| "warfarin_like": [ |
| "bleeding" |
| ], |
| "nsaid_like": [ |
| "bleeding", |
| "renal_injury" |
| ] |
| }, |
| "substitutions": { |
| "nsaid_like": [ |
| "acetaminophen_like", |
| "topical_nsaid_like" |
| ], |
| "benzodiazepine_like": [ |
| "non_benzo_sleep_support" |
| ], |
| "opioid_like": [ |
| "non_opioid_analgesic" |
| ] |
| }, |
| "taper_required": { |
| "warfarin_like": false, |
| "benzodiazepine_like": true, |
| "metformin_like": false, |
| "statin_like": false, |
| "ace_inhibitor_like": false, |
| "nsaid_like": false, |
| "opioid_like": true, |
| "ssri_like": false, |
| "ppi_like": false, |
| "beta_blocker_like": false |
| }, |
| "renal_flags": { |
| "warfarin_like": false, |
| "benzodiazepine_like": false, |
| "metformin_like": true, |
| "statin_like": false, |
| "ace_inhibitor_like": false, |
| "nsaid_like": true, |
| "opioid_like": false, |
| "ssri_like": false, |
| "ppi_like": false, |
| "beta_blocker_like": false |
| }, |
| "hepatic_flags": { |
| "warfarin_like": false, |
| "benzodiazepine_like": true, |
| "metformin_like": false, |
| "statin_like": false, |
| "ace_inhibitor_like": false, |
| "nsaid_like": false, |
| "opioid_like": true, |
| "ssri_like": false, |
| "ppi_like": false, |
| "beta_blocker_like": false |
| } |
| } |
