---
license: cc-by-nc-sa-4.0
tags:
  - medical-imaging
  - mri
  - segmentation
  - neuroscience
  - unetr
---

# DOMINO++ — Whole-Head MRI Segmentation

DOMINO++ is a UNETR-based model for automated whole-head MRI segmentation into 12 tissue classes, developed by the SMILE Lab.

## Variants

- `dominopp_native.pth` — operates in native MRI space
- `dominopp_fs.pth` — operates in FreeSurfer conformed space (256³ @ 1mm isotropic)

## Tissue Classes

See `labels.json` for the full 12-class label map.

## Usage

Install the CROWN CLI and download this model:

```bash
pip install crown-cli
crown models download dominopp-native
crown segment input.nii.gz --model dominopp-native
```

---
Citation
@misc{stolte2022dominoppdomainawaremodelcalibration,
      title={DOMINO++: Domain-aware Model Calibration in Medical Image Segmentation}, 
      author={Skylar E. Stolte and Kyle Volle and Aprinda Indahlastari and Alejandro Albizu and Adam J. Woods and Kevin Brink and Matthew Hale and Ruogu Fang},
      year={2022},
      eprint={2209.06077},
      archivePrefix={arXiv},
      primaryClass={eess.IV},
      url={https://arxiv.org/abs/2209.06077}, 
}

--- 
Terms
By downloading these weights you agree to use them for non-commercial research purposes only. Redistribution of the weights is not permitted.

---