On August 3, 2020, the CFTC issued a Consent Order imposing a $4 million civil penalty and permanent injunctions against the New York Mercantile Exchange, Inc. (“NYMEX”) and two NYMEX employees, William Byrnes and Christopher Curtin, for disclosing confidential information about futures trading activity in the possession of NYMEX to commodities brokers.
1 The Consent Order demonstrates the CFTC’s continued emphasis on investigating and pursuing insider trading activity and holding exchanges accountable for their employees’ conduct. NYMEX Employees’ Insider Trading
On numerous occasions between 2008 and 2010, Byrnes and Curtin were found to have disclosed to a broker material nonpublic trade information obtained through Byrnes and Curtin’s special access as NYMEX employees. Byrnes and Curtin disclosed the following confidential information: the identities of counterparties to specific options trades; whether a counterparty purchased or sold an option; whether the option was a call or put; the volume of contracts traded; the expiry; the strike price; and the trade price. According to the Consent Order, this conduct violated Section 9(e)(1) of the Commodity Exchange Act (the “Act”), which prohibits insider trading, and CFTC Regulation 1.59(d)(1)(ii), which prohibits disclosure of material nonpublic information obtained through special access as an employee of a self-regulatory organization. Section 9(e)(1) and CFTC Regulation 1.59(d)(1)(ii) are specific to “registered entities” such as contract markets, clearing organizations, and swap data repositories, but does not apply to market participants. Accordingly, this action was not based upon the CFTC’s fraud-based manipulation authority.
In addition to imposing a monetary penalty, the CFTC imposed permanent trading bans on Byrnes and Curtin. Curtin voluntarily resigned from NYMEX in April 2009, and Byrnes was terminated in December 2010. Given that the relevant activity occurred between 2008 and 2010, it is likely that the defendants entered into an agreement tolling the statute of limitations during the investigation. The CFTC also charged Ron Eibschutz, the broker who received the nonpublic information, with aiding and abetting the NYMEX employees’ violations of the Act. The August 3, 2020 Consent Order does not resolve the CFTC’s claim against Eibschutz.
NYMEX Found Vicariously Liable
The Consent Order holds NYMEX vicariously liable for the actions of Byrnes and Curtin, imposing a $4 million civil monetary penalty jointly and severally on NYMEX, Byrnes, and Curtin, with the liability of the individual traders capped at $500,000 in total. Additionally, the CFTC enjoined NYMEX from further violations of Section 9(e)(1) of the Act and CFTC Regulation 1.59(d)(1)(ii).
This enforcement action against NYMEX is the “first time the CFTC has charged an exchange with violations of the proscription in the Act and the CFTC regulations against disclosures of material nonpublic information by exchange employees.”
2 Director of Enforcement James McDonald emphasized that “commodity exchanges are responsible for violations of the Act or CFTC regulations by their officials, employees, and agents within the scope of their employment or office.” 3 This serves as a reminder that exchanges must take affirmative steps to ensure that their employees fully understand their obligations under the Act and the CFTC rules. ******
If you have any questions regarding this client alert, please contact one of the authors, any member of our CFTC team listed below, or the Willkie attorney with whom you regularly work.
Click here to download this article.
1 CFTC v. William Byrnes, Christopher Curtin, NYMEX, and Ron Eibschutz, No. 13 Civ. 1174 (VSB) (Aug. 3, 2020). 2 Commodity Futures Trading Commission, NYMEX and Two Former Employees to Pay $4 Million for Disclosing Material Non-Public Information (Aug. 4, 2020), here. 3 Id.


An observational cohort study with a large number of patients was conducted to compare the clinical outcomes of treatment with first-generation autologous chondrocyte implantation to that of treatment with autologous bone marrow stem cells. Seventy-two matched (lesion site and age) patients underwent cartilage repair using chondrocytes or bone marrow stem cells. There was a significant improvement in the patients quality of life after cartilage repair in both groups. However, there is no difference between the two groups in terms of clinical outcomes. The authors concluded that bone marrow stem cells are as effective as chondrocytes for articular cartilage repair, and have advantages in terms of requiring less knee surgery, reduced costs, and minimised donor-site morbidity (Nejadnik et al., 2010)


Carpet beetles are incapable of biting a human in any perceptible way. Their mandibles are not large enough to inflict a painful bite and they carry no venom. Due to this there are virtually no health concerns from being bit by a carpet beetle.
However, there are potential health concerns when the beetles gain access to human foods. Cross-contamination can become a big risk in these food situations and this should be taken seriously.
With Halloween just around the corner, its time for larger-than-life creepy, crawly creatures skittering across lawns, lurking in dark alleyways and dropping out of nowhere to frighten their hapless victims.


As a pediatrician, I often treat kids that are “Neonatal Intensive Care Unit (NICU) grads”, which refers to babies that needed NICU care after birth due to prematurity or other life-threatening medical conditions. I’m always inspired by these patients and their families because they have persevered through very challenging experiences.
Project Sweet Peas is a 501(c)3 national non-profit organization coordinated by volunteers, who through personal experience have become passionate about providing support to families of premature or sick infants and those who have been affected by pregnancy and infant loss. This amazing organization acknowledges the importance of parental involvement in the NICU, and seeks to promote family-centered care (FCC) competencies in hospitals nationwide. Care packages, hospital events, peer-to-peer support, financial aid, educational materials, and other Project Sweet Peas services, support the cultural, spiritual, emotional, and financial needs of families as they endure life in the NICU.
Project Sweet Peas also makes a lifelong commitment to support families experiencing pregnancy and infant loss. In a baby’s last moments, families are encouraged to make cherished memories with custom Project Sweet Peas keepsake items. Healing and remembrance continue to be fostered through programming such as peer-to-peer support, and their annual candlelight vigil.
I’m so impressed by the wonderful work Project Sweet Peas is doing for so many families and babies, as well as their mission and values. The support they provide to families of fragile infants and the way they inspire them with the hope of tomorrow really touches this mama’s heart.
Dr. Sylma is committed to supporting Project Sweet Peas with a portion of our sales. Please join us in supporting these families who have had their world turned upside down and are experiencing tremendous difficulty in bringing their children into health, and also those who tragically have lost their little ones. Together, we can truly serve these families in need.
Love always,


EVENT SUMMARY
When it comes to developing a pragmatic infrastructure and cloud strategy, there are key areas to address: How do you shift from legacy systems to embrace future needs? How do you design for uncertainty? What cloud strategies and options should you consider?
Gartner Analyst, David J. Cappuccio, Chief of Research for Infrastructure, responsible for research in enterprise data center strategies and trends, data center cloud and hybrid strategies and data center consolidation and migration strategies answers these key questions and shares emerging infrastructure trends and strategies.
Richard Zheng, President of Servpac, a local Telecom and IT solutions provider, also shares trends he sees in Hawaii business’ adoption of the cloud and how flexibility is a key component to designing a strategy. He shares how he leverages expertise from Gartner as he prepares his organization to meet the changing needs of customers.


Overtime Wage Claims Under The Fair Labor Standards Act And Indiana Law Overtime Wage Claims Under The Fair Labor Standards Act And Indiana Law
Many American’s live paycheck to paycheck, making untimely or improper payment a burden for many workers. Employees may hesitate, however, to challenge their employer and assert their right to be paid the amount they have earned.
The Fair Labor Standards Act (FLSA) and other applicable state law protect an employee’s right to timely and correct payment of overtime hours.
Fair Labor Standards Act: Overtime Pay
The U.S. Wage and Hour Division of the Department of Labor (USDOL) specify that any employee covered by the FLSA must receive overtime pay for any hour worked over 40. Additionally, the rate of overtime pay must be at least 1.5 times the employee’s regular base pay. These rules do not apply to weekend or holiday hours, however, which may remain at an employee’s standard rate.
Occasionally an employee is hired to work more than 40 hours per week. The FLSA has provisions to ensure fair overtime payment for these situations as well. This ensures employers cannot avoid paying overtime based upon an employee’s contract.
FLSA Vs. Indiana Wage Claims Act
For those individuals not covered by the FLSA, it is possible to have a claim arise under the Indiana Wage Claims Act (Act). This Act allows employees who have received less compensation than they are owed, or have not received their compensation on time, to receive back-wages, as well as penalty damages and attorney fees.
The Indiana Department of Labor (IDOL) limits these claims and states that the maximum amount a claim arising under the Act may be $6,000. Any amount exceeding this limit should be brought to the attention of a private attorney to determine how to proceed.
Collecting Wages Owed
If anyone has questions about the FLSA or the Act they should contact an experienced employment law attorney. An attorney can help determine your eligibility and the viability of a potential claim.
Finally, not receiving the proper income or not receiving it on time can be a very time-sensitive dilemma. Families need to pay their mortgage, their phone bill, and put food on the table. While the USDOL and IDOL do their best to resolve wage disputes as quickly as possible, it is recommended an employee consult an attorney to ensure all procedures are followed correctly and promptly.


Pierpaolo Polzonetti
This article explores how food and drink in opera convey meaning, define relationships, trigger psychophysical reactions, and denote dramatis and singers’ personae. It proposes a basic theoretical foundation of “operatic gastromusicology” by outlining five primary functions of food in opera: social, intimate, denotative, medicinal, and dietary. These five functions are exemplified through the analysis of gastronomic signs in Verdi’s
Traviata. The opera and its performance history illustrate how the production of this opera reflects the changing culture of food and the body. Luchino Visconti’s production in Milan’s La Scala in 1955, with Maria Callas as the consumptive protagonist, was in this respect a watershed in the history of opera. The singer’s rapid and prodigious weight loss prior to this performance triggered an epochal shift in opera culture toward an unprecedented conflation of the dramatis and singer’s persona. Linda Hutcheon and Michael Hutcheon
The singing and acting performer in staged opera
has and also performs a body that is both a biological entity and an ideological construct: its race, sex, physique, and age are all given meaning by directors—and audiences. Within the contexts of feminist, queer, and disability studies, this chapter reads the “marked” body of the protagonist of David Alden’s 2008 production of Gaetano Donizetti’s 1835 Lucia di Lammermoor as the literal embodiment of the excruciating vulnerability of Lucia as subject through the medium of her youthfulness and her mixed race: a Down syndrome child sexually abused by her brother on stage. Just as the opera’s use of coloratura is a marked musical gesture of madness in dramaturgical terms for the “voice in performance,” so the specifically marked corporeal body of Lucia was crucial to this production’s dramatic power, as well as the ethical and political issues it raised. Hanne Blank
This chapter proposes that in the grand opera of the nineteenth century, sexuality and dis/ability combine with opera’s musical, literary, and dramatic elements, enabling experiences of the sublime within the context of human embodiment. Operatic representation of disability, including madness and lovesickness, enables audiences to both experience and contemplate uncontrollable and overwhelming forces, the essence of Arthur Schopenhauer’s conception of sublimity. The rise of these representations in nineteenth-century opera coincides with increasingly influential concepts of normative bodies, bodily controllability, and marginalization of bodily excess and disability. Opera’s textual, musical, sung, and acted representations of embodied excess, disability, and physical extremity enhance audiences’ immersive witnessing of and physical empathy with those representations.


Long-term kidney allograft survival remains a major clinical challenge. Recurrent glomerulonephritis disease, including recurrence of IgA nephropathy (IgAN), is a significant barrier to long-term kidney allograft survival. We performed a retrospective, observational study to evaluate the role of everolimus (EVR) in the risk of recurrent IgAN.
The study included data from 135 patients aged ≥16 years with biopsy-proven IgAN on native kidneys who underwent a kidney transplant (KT) between December 2002 and December 2018. Patients who underwent de novo KT received mycophenolate mofetil (MMF) (n = 107) or EVR (n = 28). The mean recipient age in the MMF and EVR groups was 44.9 ± 13.7 and 41.1 ± 10.1, respectively. The median (interquartile range) follow-up period was 90.9 (64.9-115.3) and 21.2 (11.4-30.6) months, respectively (< .0001). All patients received continuous corticosteroid and tacrolimus therapy. The death-censored graft survival rate after KT and the recurrence-free survival rate did not differ significantly between the groups. Univariate and multivariate Cox regression analyses identified EVR for de novo KT as an independent predictive factor for recurrence-free survival (P = .024). Our findings suggest that EVR-based regimens with tacrolimus and corticosteroid therapy for de novo KT reduce the recurrence of IgAN compared with MMF-based regimens with tacrolimus and corticosteroid therapy. Copyright © 2020. Published by Elsevier Inc. References
PubMed


Despite stereotypes to the contrary, others have discovered and are promoting the inspiring stories & messages freely given by our elders.
Gail Zugerman offers up these stories through her podcast - GrowingOlderWithGusto. In this episode, Gail and Lee compare notes about their experiences with the older generations and what they have learned from this engagement. Together they explore lessons such as how successfully aging people view their past & future and how to turn an ordinary past into an extraordinary future. You won't want to miss Gail's 5 keys that are critical for successful aging. This conversation will surely inspire an upgrade in your thinking as to how you see yourself on your forward path.
Despite stereotypes to the contrary, others have discovered and are promoting the inspiring stories & messages freely given by our elders.
Lee Deeply respects the wisdom and perspectives of the elders in our culture. The changes they have seen in their lifetime often provide useful insights about what lies at the heart of many of our current events. In this episode, Lee has the opportunity to speak with 94-year-old elder - Priscilla. They discuss the culture and society as it was and how it has evolved to the characteristics around us today. Priscilla points to many cultural factors such as the elimination of Sunday Blue laws, the introduction of factories, World war 2 and the Vietnam War, and the rise of social media as a cultural influence. She also muses on the many pursuits she has engaged in during her time - piano, painting, Tai-chi. Her ability to speed read helps her to stay cognitively sharp and up-to-date on current events. Join Lee in this intriguing conversation with an engaging elder to see where your insights will fall.
Join Lee as he continues to share his insights and experiences in handling the challenges of aging. In this episode, he shares the difficulties of going blind in one eye. Aging forces us to accept who we are becoming. The question is: How are we dealing with those challenges? Are we sidelined by them, or do we choose to see these as opportunities to learn more about ourselves and the possibilities that our inevitable aging bring? Lee goes into his personal history in facing medical trauma, knowing that the master is not the one who has the best circumstance, but one who makes the best from any circumstance. Lee firmly believes that you cannot have bad without good. They are flip sides of the same coin. As he promised, Lee allows his listeners and Insider’s Club members to follow along with his aging journey as he explores these somber adventures with acute glaucoma and blindness in his right eye.
Lee is back to explore how our thoughts evolve with us. More specifically, this episode discusses the human value system and how it typically changes with the years. Human values are the virtues that guide us to take into account the human element when we interact with other human beings. They determine how we feel and treat others on a small and large scale. These values help us to determine what is right or wrong in our lives. Lee has observed that our values (e.g. Achievement, Hedonism, Security, Conformity, Tradition, Power, etc.) changes as we age. He offers 4 introspective questions whose answers reveal who you were, as well as who you have become in relation to your values. He also shares his own answers to these questions to show the changes that have occurred in his thinking over the past 25 years. Listen and join Lee in a powerful tool to help you forgive your past and chart a brighter future.
Lee's guest for this episode is Dr. Rachna Patel, whose practice has given her the reputation of being the Medical Marijuana Expert. Together, they bring this controversial topic into the light to answer many common questions (and a few uncommon ones). The conversation is packed with information such as - Medical vs. Recreational; the medical conditions that can be directly addressed with these treatments; who should avoid medical marijuana; Big Pharma's role, plus much more.
The challenges of aging is something most of us are not yet familiar with. But we will all face these challenges. And who will teach us how to see and approach these difficulties (or pleasures) of getting older. This episode introduces "the Aging Academy" where Lee offers to become a "pioneer for aging" by exposing his personal challenges that affect him as the years mount up. Lee, like everyone else, is getting older. Increasing stress, shifting priorities, aching bones, and changing social patterns all have their impact, and Lee wants to share with you, through the Aging Academy, how he is (or is not) dealing with these issues in his life. Lee talks about his anticipation and expectation for the Aging Academy project to be a source of specific information on tackling common problems of aging in our culture


The total area of Queensland that is drought-declared has risen to 65.2 per cent after a significant lack of rainfall across central, southern and south east Queensland.
Agriculture Minister Mark Furner has accepted the recommendations of local drought committees following their assessment of seasonal conditions and drought declared five additional shires and extended or issued part drought declarations in four others.
The new declarations cover Ipswich Regional Council, the remainder of Western Downs Regional Council, Scenic Rim Regional Council, the remainder of Banana Regional Council, Gladstone Regional Council, Rockhampton Regional Council, Livingstone Shire and the southern portion of the Central Highlands Regional Council including part of the Woorabinda Aboriginal Shire Council area, defined as south of the Capricorn Highway.
Any producer who is experiencing difficult conditions in any council area that is not drought declared, that they can apply for an Individually Droughted Property (IDP) declaration giving them the same access to drought assistance as an area declaration.
Producers can access further information at longpaddock.qld.gov.au.
For further information on drought assistance visit daf.qld.gov.au or call the Customer Service Centre on 13 25 23.


Over the last few years, the global iGaming industry has reached new, unprecedented heights. In turn, this has resulted in contemporary gamers exploring a wide array of diverse, casino-oriented markets. Intriguingly, this shift in user trends has been indicative of the ever-changing nature of the sector.
While the emergence of online casinos has proved fruitful to numerous countries, the market’s growth has highlighted the influence of Malta regarding digital gambling. Fundamentally, the Southern European island country’s existing gaming outlook is a reflection of broader alterations. So, let’s consider Malta’s approach to in-house and online gaming.
Analyzing Malta’s Land-Based Offerings
Recently, increasing numbers of casino players have sought to explore numerous offerings available at digital operators. Primarily, this is a result of the accessibility, convenience, and variation that comes with web-based platforms. Despite that, in-house opportunities remain a focal point of the country’s in-house entertainment.
Although there is little choice available to those seeking a land-based casino experience, with VisitMalta listing four establishments that provide traditional offerings, the scale of each illustrates their local appeal. Of those available, Casino Malta by Olympic Casino is the country’s largest, with its opportunities covering poker, table games, and 300 video machines. Since opening in 2015, the facility is considered to be Malta’s best casino because of its diverse approach to in-house entertainment.
However, despite the popularity of land-based casinos, the emergence of digital alternatives has enabled Malta to explore varied approaches to contemporary betting. In this regard, it’s apparent that the country is something of a microcosm of global trends. As per Malta InsideOut, slot machines generally take a backseat compared to roulette, for example, which is the island country’s most popular game. Interestingly, this is somewhat similar to the United Kingdom. Of all the activities, a Gambling Commission report states that sports betting is participated in the most, as opposed to slots.
Diversifying to Become an Industry Leader
While land-based establishments have yet to allow Malta to explore the development of in-house slots, digital alternatives have proved to be undeniably beneficial. Contrary to Malta’s limited real-world casinos, the country boasts a significant presence within the iGaming sector. Crucially, the Malta Gaming Authority regulates one of the country’s major economic contributors in the form of both in-house and digital casinos.
Because of the sector’s well-regulated nature, Malta has become the industry’s leading figure, morphing itself into the world’s iGaming capital. To showcase this, a whole host of contemporary operators are licensed by the MGA, including Caxino. The platform itself offers prospective players a whole host of gaming opportunities, such as live variants, table games, and slots, such as Aztec Gems Deluxe and Deadwood.
Interestingly, this showcases how the country’s influence has enabled it to explore aspects of the casino industry that have yet to hit the heights at land-based facilities. With slots now becoming a central part of iGaming, Malta’s influence could aid in enhancing the appeal of machine games across the world.
In a Position to Bring About Change
Digitally, Malta is a dominant player in the world of casino gaming. While it remains to be seen if this leading status will impact real-world slot popularity, few can argue that it won’t have any negative implications on participation. In becoming a central figure in the iGaming industry, it appears apparent that local gaming trends in Malta are mirrored by players across the globe, hence the need for well-regulated operators.


Abstract
Drawing on institutional theory, this study examines how adherence to a number of 'institutional' and 'technical' environmental forces can influence the business success of managed cam organizations (MCOs). The standards studied include: (1) institutional forces: socially accepted procedures for delivering care (access to quality care, availability of information, and delivery of care in a personal manner); and (2) technical forces: industry standards for cost control and efficient use of financial and medical resources. The most significant finding is that successful MCOs must conform to both institutional and technical forces to be successful. MCOs that conform to either one or the other type of standard were no more successful than those that conformed to neither. These findings have several important implications for MCO strategy. First, to be successful, MCO executives must understand the external environment in which they operate. They must anticipate and respond to shifts in that environment. Second, this understanding of the external environment must place equal emphasis on societal demands (e.g., for accessible care and information) and on technical demands (e.g., for cost-efficient care). These findings may well reflect that once managed care penetration reaches relatively high levels, marketshare can no longer be gained through cost-efficiency alone; rather, enrollee satisfaction based on societal demands becomes a key factor in maintaining and gaining marketshare. Institutional theory provides some strategies for accomplishing these goals. Cost-containment strategies include implementing policies for cutting costs in areas that do not affect the quality of care, such as using generic drugs and reducing administrative excesses and redundancies. At the same time, MCOs must implement strategies aimed at improving conformity to prevailing societal perceptions of appropriate care, including providing patients more freedom to choose their physicians and encouraging and rewarding care providers for being friendly and personable. An MCO should work to inform the public of the organization's efforts to provide high-quality, low-cost medical care in a friendly, convenient manner.
ASJC Scopus subject areas Leadership and Management Health Policy Strategy and Management


Reasons to Seek a PE Partner
For owners, the thought of making a business transition or adding a partner can be very stressful. However, working with a PE partner is often:
An ideal way to overcome succession challenges and provide ownership to management, family members or others The most viable method of expanding a business or acquiring a competitor A sound way for owners to realize liquidity while maintaining ownership — a win-win for those who believe in their company's future, but don’t want to face all of the risks alone The most direct path for a company to make fundamental business improvements that often are more difficult to achieve under current ownership constraints The most viable way to ensure your company isn’t left behind during an economic phase where many industries are experiencing consolidation


Abstract
HER2 is overexpressed or gene amplified in 20%-25% of breast cancers. The anti-HER2 monoclonal antibody trastuzumab targets HER2-positive tumors, inhibiting proliferation and inducing cell death via extracellular and intracellular mechanisms. The clinical benefits observed with trastuzumab in the metastatic setting provided the rationale for assessing trastuzumab in the treatment of early breast cancer. Four large phase III adjuvant trials (NSABP B-31, NCCTG N9831, HERA, and BCIRG 006) investigated the efficacy and safety of 1 or 2 years of trastuzumab given in combination with or after standard adjuvant chemotherapy. The addition of 1 year of trastuzumab to adjuvant chemotherapy significantly improved disease-free survival (DFS) by 33%-52% and overall survival by 34%-41% in the 4 trials. The DFS benefits were observed regardless of age, nodal status, hormonal status, or tumor size in all trials. The cumulative incidence of congestive heart failure or cardiac death ranged from 0-0.9% in the control arms and 0-3.8% in the trastuzumab-containing arms. These were below the safety cutoff points set by the individual studies' independent data monitoring committees, indicating acceptable cardiac safety. Risk factors associated with cardiac dysfunction included baseline left ventricular ejection fraction level, hypertension, and older age. The addition of trastuzumab to adjuvant chemotherapy provides significant survival benefits with a positive benefit/risk ratio. Ongoing and planned trials correlated with basic science will enhance our understanding of HER2-positive disease, leading to treatment optimization and further improvements in patient outcomes.
Keywords c-Myc Cardiac toxicity Chromosome 17 Paclitaxel Topoisomerase IIα ASJC Scopus subject areas Cancer Research Oncology


On 14 June 2016, Tania Molteni, guest speaker from the collaborative project COOPENERGY and researcher at Bocconi University in Italy joined the 3
rd Partners’ Meeting of the multEE project in Sarajevo. Ms Molteni’s presence aimed to increase learning and exchange of experience between projects with a similar focus. During her talk, she addressed the importance of multi-level governance for sustainable development. She also presented a user guide on Multi-Level-Governance focusing on the coordination between the regional and local levels, which was created with the aim of developing sustainable energy concepts.
The COOPENERGY project was funded by the Intelligent Energy Europe Programme and aimed at supporting the development of more effective collaborative working between regional and local public authorities to maximise positive energy planning outcomes and accelerate reduction of greenhouse gas emissions.


New data from the Department of Health is showing a growing share of very young children and teenagers are testing positive for COVID-19 compared to earlier in the pandemic, a worrying sign that could have major implications for New York City’s in-person schooling initiative.
Compared to other age groups, children aged 4 and under showed the highest weekly positivity rate: 3.2% for the week ending on October 31st, compared to 2.2% for city residents overall. The positivity rate was more than double that of the first week of September, when 1.4% of children under 4 tested positive.
Children ages 13 to 17 had the second highest weekly positivity rate. In early October, the rate among that group soared to 3.9% before declining to 2.6% in the last week of October.
Interestingly, positivity rates for children aged between 5 to 12 also began rising after September, but after peaking at 2.8%, have since declined to 1.5%.


The "gluten-free" final rule, published by the U.S. Food and Drug Administration (FDA) in 2013, is intended to provide safe food choices for people suffering from celiac disease. This final rule is not applicable for cosmetic products. As a result, analytical methods for gluten estimation in cosmetics are warranted to aid in the determination of the presence of gluten in these products. A survey of 36 cosmetic products was conducted to measure gluten content by three different ELISAs. None of the nine gluten-free-labeled cosmetics included detectable gluten. The gluten content in six cosmetics was 15.2-1453.5 ppm by one competitive ELISA, whereas three cosmetics contained 11.7-572.3 ppm gluten when quantitated with two sandwich ELISAs. Gluten or hydrolyzed wheat protein was found as an ingredient in five cosmetics with detectable gluten levels. A poor recovery of gluten was observed for most of the cosmetics in the foundation/blush/powder category by ELISA kits. This finding warrants a need for improved analytical methods for gluten estimation in cosmetics.


If you’ve ever considered entering the trading market, you may have heard people dissuading you and telling you that it is a gamble. While they are not wholly wrong, they aren’t entirely right either. Sure, your luck plays a role in the outcome of your investment, but there are several additional factors and trading strategies you can leverage for a fruitful return on investment. Once you learn these trading strategies, you can master the art of market investments. Let’s find out what momentum trading is, and the critical factors involved in implementing strategies for it.
What is momentum trading?
Momentum trading is defined as the practice or act of buying and selling trading market assets, as per their recent price trend strengths. The practice assumes the premise that if enough force is applied to a price move, the price will continue moving in the same direction. Assets start attracting more attention from investors and traders upon reaching a higher price, which, in turn, pushes the price to higher heights. This trend continues until numerous sellers enter the market. Once there are enough sellers in the market, the momentum strategy is said to be in force, causing the momentum to change its direction, and forcing the asset’s price to reduce.
How do traders implement momentum trading strategies?
Momentum traders attempt to identify the strength of a trend in a given direction. Once this happens, they open a position, hoping to gain from the expected change in the asset’s price. They then close the position when the trend begins losing its strength. Momentum traders primarily focus on the main body of the move of the price instead of attempting to find or analyse the top and bottom of a given trend. Their primary objective is to exploit the market sentiment and the herd mentality, i.e. the general tendency among traders to follow a proven concept and benefit from it.
Factors involved in implementing a solid strategy
The momentum trading system is primarily based on three key factors, based on which strategies are implemented. They are as under
1.
The volume of the assets traded
In terms of momentum stock trading, the volume is defined as the amount of the asset traded, in a specific time frame. It represents the total number of assets traded as opposed to the total number of transactions. As such, if ten buyers buy one asset each, it appears the same as if one buyer has bought ten of the same asset. Volume, in momentum trading, is rather crucial as traders should be able to take rapid entry and exit positions. The positions they take depends on the presence of a steady number of buyers and sellers. A market with a high number of traders is known as a liquid market, in which traders can easily exchange assets for cash. If there aren’t enough traders, the market is deemed illiquid.
2.
The volatile market conditions
In the momentum trading system, traders consider volatility as their primary source of income. Volatility represents the degree to which an asset’s price changes. A highly volatile market represents the presence of a significant price swing, whereas low volatility means that the market is comparatively stable. In momentum trading, traders attempt to seek out volatile markets and take advantage of the rise and falls in the asset’s price in the short term. These traders attempt to capitalise on the volatility of the asset’s prices. Since volatility represents risks, momentum traders typically implement risk management strategies to protect their trades from the volatile market movements, including setting the stop-loss limits.
3.
The timeframe of the trade
The final factor involved in implementing a water-tight strategy is the total time taken to enter and exit a trade. Most momentum trading strategies focus on short-term movements in asset prices. However, how long a trend lasts entirely depends on the duration taken by the trend to maintain its strength. The time frame strategy is ideal for traders who choose to employ a longer-term trading style, for instance, position trading. Short-term traders can also combine this strategy with other strategies such as scalping and day trading.
Final note:
As a market trader, you can always benefit from having multiple strategies up your sleeves. It would help if you also familiarise yourself with the various trading indicators such as the Momentum Indicator, the Relative Strength Index (RSI) Indicator, Moving Averages Indicator and the Stochastic Oscillator Indicator. You can also identify the assets you may be interested in investing and practice trading on various online simulators before you start trading live. For more details on momentum trading, you can contact an Angel Broking Expert.


Right ventricular (RV) function plays a pivotal prognostic role in multiple cardiac diseases. Echocardiography guidelines recommend that RV quantification be performed in the RV-focused view, which is theoretically more reproducible than the four-chamber (4Ch) view. However, differences between views in RV size and function measurements have never been systematically studied. Accordingly, the aim of this study was to compare (1) RV size and function parameters obtained from the RV-focused and 4Ch views and (2) test-retest variability between these two views.
Researchfor care


Water and Society
Human societies strongly rely on access to water resources, which are essential to support livelihoods and provide favorable conditions for sustainable development. While benefiting from water services and struggling with water-related disasters (floods and droughts), humans also alter the hydrological regime by building dams, canals, levees, etc... This work aims to improve our understanding of human-water interactions, and the dynamics emerging from the feedbacks between hydrological and social processes.
The purpose of this project is to explore water-related issues and their link to sustainable development. To this end, it aims to better understand the dynamic relationships between hydrology and societies. This also require exploring how societies change the hydrological regime while, at the same time, hydrological changes simultaneously shape societies, i.e. socio-hydrology.
At the department, the studies dealing with the interface between water and society are organized around three main research lines:
Global hydrology Engineering hydrology Socio-hydrology
The project activities are partly funded by VR and FORMAS and linked to the new scientific decade Panta Rhei (2013–2022) of the International Association of Hydrological Sciences (IAHS). The work is also carried out in support of three strategic research goals of the department: natural hazards, climate and sustainable development.


Benign metastasizing leiomyoma (BML) is the term used to describe multiple benign pulmonary leiomyomatous lesions occurring in patients with a previous history of uterine leiomyoma. On the other hand, pulmonary fibroleiomyomatous hamartoma (FLH) is also multiple nodules and the discrimination of the nodules between BML and FLH is not determined. We report the case of 36-year-old woman who had a previous history of uterine leiomyoma. The woman was referred to our hospital for evaluation of asymptomatic bilateral nodules in chest roentgenogram examination. A chest X-ray showed multiple nodules in bilateral lung. Chest computed tomography (CT) scan showed round nodules well-defined margins in bilateral lung. Thoracoscopic partial resection of the lung was performed. Pathological examination revealed that the tumor composed of spindle-shaped smooth muscle cells and its characteristics were remarkably similar to those of the previously resected uterine leiomyoma. Therefore, these lung tumors could be considered to be lung metastases from a uterine leiomyoma (benign metastasizing leiomyoma).


As cars get more and more feature packed, another equipment that has found into several new models is a digital video recorder (DVR), also known as a dashcam.
Having video evidence from a DVR will save from unnecessary “he said, she said” disputes arising from an accident.
Many cars these days offer a built-in front-facing DVR while some manufacturers like Toyota will even offer a rear-facing camera for an additional RM 350, which is a small price to pay for better peace-of-mind.
If your car isn’t equipped with a built-in DVR, fret not as aftermarket solutions are available. To keep things simple, these are some features worth looking out for while shopping for a new DVR.
Video resolution: The minimum video resolution is 1080P, but 2160Pand 4koffer sharper video footage, at the expense of larger file sizes. Framerate: 30 frames per second (fps) is the norm these days, but 60 fpsis ideal. Higher fps also means larger file sizes Memory card: We recommend shopping for memory cards that are designed specifically for DVR usage, which are often labeled as ‘ High Endurance’. Manufacturers such as Transcend, Kingston, Samsung, and SanDiskoffer such cards. Memory card capacity: Go with at least 32GB, 128GBif you can afford. Display size. Good to have a display to align and adjust the DVR, but not a must-have. Some DVRs make do without a display, relying instead on WiFi connection for users to view recordings. G-Sensor. When the G-Sensordetects a crash, the DVR will lock the video recording to prevent it from being deleted or overwritten.
Apart from these requirements, we also recommend users to check actual video footage from the DVR before purchasing, as a blur video footage is useless as an evidence. It is also worth watching DVR reviews on YouTube before making a decision.
Furthermore, it’s a good idea to watch video footages in various scenarios, not just in daylight. A good DVR is able to capture sharp footage regardless of the lighting conditions.
Brands to look out for include
Viofo, Xiaomi, 70Mai, Transcend, and Blackvue. These are reputable and established brands that offer great cameras that various price points.
As for installing the DVR, we are aware that wire-tapping kits are common, but know that these methods will void the car’s warranty as it tampers with the car’s original wiring, so do it at your own risk.
It’s best to use the 12V socket/ cigarette lighter/USB as the power source.
So there you have it, a reasonably comprehensive guide on how to purchase a DVR.


This body of art is an on-going exploration of the intersection between the body, home, and the landscape.
Previous iterations of this installation play space can be found at these links:
Excerpt from PhD Exegesis concerning this exploration:
“This research grew from critiquing the sense of tension between my body and the environment. I found this tension repeated in my inquiry through my frustration at the visual dominance of mathematical space in my home’s interior and the surrounding urban environment. Critiquing this frustration led me to identify how habitual perception of these seemingly stable, standardised environments, in coincidence with mundane routine, can dull phenomenological depth: we don’t so much open out to these spaces as contain our subjectivities within them. Deliberation on these observations broke with this habitual perception at various points, prompting me to sense these ordinary environments more deeply as a world that strikes my body on its sensory surfaces.
Gaston Bachelard notes that “a house is first and foremost a geometrical object, one which we are tempted to analyse rationally.”
[1] However, Bachelard elaborates, the lived house is transposed to the human plane whenever it “is considered a place of cheer and intimacy.” [2] In this fullness, the primacy of the home’s rational geometry yields to the home’s dream world. In seeking to plot the interaction of this geometry and its dream, I gradually disrupted the sensible partition of my common sense. In fact, my aversion to the mathematical, the utilitarian, and the standardised fixed in place my perception of inert, dead, matter.” (p. 135 – 136)
[1] Bachelard,
The Poetics, 48.
[2] Bachelard,
The Poetics,48.


I feel as though I live in my own reality. I uniquely experience the world, and at times, it separates me from others.
My emotions are very intense, and I struggle with both experiencing and controlling them. Other than experiencing these emotions, my relationships are most affected by BPD and my feelings.
At times, my emotions build-up, and I’m unable to keep them inside. I become erratic and unstable. Most of the time, I can keep my feelings inside. However, it is not that I am burying these feelings; my emotions change moment to moment. The difference is every one of my feelings is extreme and will often be viewed as an overreaction. I cannot burst, break down, or express these unpredictable and sometimes irrational emotions.
When I am with others, I may not say much or always seem ‘there’ because my mental reality is going a mile a minute. I am processing what the other person says, I interpret and internally react; I manage my emotions.
Often I struggle to relate. The issues I deal with daily are not the best conversation starters, and most people in my life cannot connect to what I go through. I find myself jealous of their goals and abilities. I am so proud of those I love, but it reminds me of what I cannot do and how easily it comes for them.
Being around others drains me. While I enjoy being around those I love, I need a lot of alone time. I can spend more time with those I am closest to. They understand me better than most, so they are more comfortable for me to be around. Although they may not understand my life, they support me and love me for who I am. Even so, I keep myself at a distance, protecting my mental state.
There are vital signs for when I have been around others too much or need time alone. I become irritable; I emotionally react to others and am often controlled by these emotions. I attach to those I’m around. I usually expect too much of people but am unable to communicate my needs. I will take others’ actions personally, so it affects me when I am pulling people too close.
Relationships are essential for a happy and healthy life, but it is also necessary to have healthy boundaries and understand one’s needs. I need people in my life to connect, feel loved and supported, grow within relationships, and share experiences. Relationships are complicated for me, but they also make life worth it.


Symbolic Math Toolbox™ operates on numbers by using either numeric or symbolic arithmetic. In numeric arithmetic, you represent numbers in floating-point format using either double precision or variable precision. In symbolic arithmetic, you represent numbers in their exact form. This topic compares double-precision, variable-precision, and symbolic arithmetic.
Numeric computations in MATLAB
® use double-precision arithmetic by default. For example, evaluate the expressions 10001/1001, π, and . The results are converted to double-precision values. x = 10001/1001 y = pi z = sqrt(2) x = 9.9910 y = 3.1416 z = 1.4142
For more information about double-precision arithmetic, see Floating-Point Numbers. This arithmetic is recommended when you do not have Symbolic Math Toolbox or are using functions that do not accept symbolic input. Otherwise, exact symbolic arithmetic and variable-precision arithmetic are recommended. To convert a symbolic value to double precision, use the
double function.
Variable-precision arithmetic using
vpa is the recommended approach for numeric calculations in Symbolic Math Toolbox. You can specify the number of significant digits when performing calculations with variable-precision arithmetic.
For example, use
vpa to evaluate the fraction 10001/1001. By default,
vpa evaluates inputs to 32 significant digits. Approximate the fraction 10001/1001 to at least 32 significant digits.
vpa(10001/1001) ans = 9.991008991008991008991008991009
Approximate the fraction to at least 8 significant digits. Change the number of significant digits by using the
digits function.
digits(8); vpa(10001/1001) ans = 9.991009
In variable-precision arithmetic, you can increase the number of significant digits for greater precision. Alternatively, you can decrease the number of significant digits for faster computations and decreased memory usage.
Symbolic Math Toolbox provides the
sym and
syms functions to perform exact symbolic computations. In symbolic arithmetic, you can perform computations involving numbers and variables in their exact form, such as
x/2,
2^(1/2), or
pi. The following three examples show several calculations that are performed in symbolic arithmetic.
Use
sym to create symbolic numbers. Express the irrational numbers π and in symbolic form.
x = sym(pi) y = sqrt(sym(2)) x = pi y = 2^(1/2)
When you declare a number, MATLAB automatically converts the number to double precision. For example, declare the integer
80435758145817515 as the input argument of
sym. The number loses its accuracy since it is bigger than the largest consecutive integer
flintmax in double precision, which is
2^53.
Z = 80435758145817515 Zinaccurate = sym(80435758145817515) Z = 8.0436e+16 Zinaccurate = 80435758145817520
sym.
Zaccurate = sym('80435758145817515') Zaccurate = 80435758145817515
You can then perform calculations with large integers using symbolic arithmetic accurately. For example, evaluate the sum of the cubes of three large integers.
Z1 = sym('80435758145817515') Z2 = sym('12602123297335631') Z3 = sym('-80538738812075974') Zsum = Z1^3 + Z2^3 + Z3^3 Z1 = 80435758145817515 Z2 = 12602123297335631 Z3 = -80538738812075974 Zsum = 42
With symbolic arithmetic, you can solve a mathematical equation. For example, solve the quadratic equation
ax 2 + bx + c = 0. Use
syms to declare the variable
x and the coefficients a, b, and c in the quadratic equation. syms a b c x eqn = a*x^2 + b*x + c == 0;
Find the solutions using
solve and return them as symbolic expressions.
sols = solve(eqn,x) sols = -(b + (b^2 - 4*a*c)^(1/2))/(2*a) -(b - (b^2 - 4*a*c)^(1/2))/(2*a)
Use
subs to substitute symbolic values for the coefficients. Set
a = 1, b = 2, and c = 3. Return the solutions of the quadratic equation as symbolic numbers. solsSym = subs(sols,[a b c],[1 2 3]) solsSym = - (8^(1/2)*1i)/2 - 1 (8^(1/2)*1i)/2 - 1
You can then convert the symbolic solutions to floating-point format in double precision or variable precision.
digits(32); solsDouble = double(solsSym) solsVpa = vpa(solsSym) solsDouble = -1.0000 - 1.4142i -1.0000 + 1.4142i solsVpa = - 1.0 - 1.4142135623730950488016887242097i - 1.0 + 1.4142135623730950488016887242097i
The table below compares double-precision, variable-precision, and symbolic arithmetic.
Double Precision Variable Precision Symbolic Example 1: Evaluate sin(π) a = pi sin(pi) a = 3.1416 ans = 1.2246e-16 b = vpa(pi) sin(b) b = 3.1415926535897932384626433832795 ans = -3.2101083013100396069547145883568e-40 c = sym(pi) sin(c) c = pi ans = 0 Example 2: Evaluate 1 - 3*(4/3 - 1) a = 4/3 1 - 3*(a - 1) a = 1.3333 ans = 2.2204e-16 digits(16); b = vpa(4/3) 1 - 3*(b - 1) b = 1.333333333333333 ans = 3.308722450212111e-24 c = sym(4)/3 1 - 3*(c - 1) c = 4/3 ans = 0 Functions Used
double
vpa
digits
sym
Data Type
double
sym
sym
Round-Off Errors Yes, the answer has 16 digits of precision. Yes, the number of digits depends on the precision used. No, the results are exact. Speed Faster Faster, depending on the precision used Slowest Memory Usage Least Variable, depending on the precision used Greatest


Is chasing storms ethical? After one profit-hungry chaser published the photograph of a dying child, it's time to re-evaluate if this is acceptable.
As someone who works as a disaster researcher and consults on emergency response, the fewer people we have in the path of destruction, the better. While yes, sometimes we still need ground-truth reports from spotters, but the NOAA satellite upgrades are getting pretty fantastic. Not only that, but spotters are trained, while anyone with a death-wish can go storm chasing. I'd even be open to debating if spotters are strictly necessary — just like I advocate for using robots to investigate active volcanoes, I'm all for getting "good enough" reports from machines instead of fantastically detailed reports from people in a risky situation.
I already habitually watch chaser footage on mute; it may be time to flat-out stop watching to keep chaser footage as it escalates into disaster-porn.


Global Health Council was unable to submit statements on all (or some) official agenda items.
Global Health Council, in collaboration with The Hunger Project, VillageReach, and Partners in Health notes that:
COVID-19 demonstrates that Universal Health Coverage in every community must be the top priority. Increased investment in all seven Global Action Plan accelerators must focus on community health systems so that tests and vaccinations can succeed.
Sustainable financingrequires a fair share of public budgets for delivery of health services and products at the tier of governance closest to the people. Community Health Centers(CHC) must be accessible (within 5km) and free to all, particularly in low-income rural communities. Every CHC must have access to clean water, sanitation,internet access, and well-trained healthcare workers. Community Health Workers(CHWs),particularly women, are critical to maintaining essential services and responding to the pandemic, ensuring every person is reached to halt misinformation, stigma, and to prevent gender-based violence. CHCs must institutionalize links with community associations, particularly women’s groups. Integrated centers to support determinants of health.CHCs can be the anchorfor one-stop access to all public services and education on health and nutrition. Health ministries should require Citizen Charters and mandatory social accountability mechanisms to ensure quality. Research & Development, innovation and access.Greater investment must be made to ensure CHWs have adequate personal protective equipment and fair compensation to support their role in deployment of testing and vaccines. Data and digital health. All CHWs should have access to remote continuing education and two-way communication at all times. Innovative programming in fragile and vulnerable states. The pandemic spotlights community resilience and the value of online platforms and connectivity to enable CHWs to network, access innovations, and share best practices even when higher tiers of government are disrupted.


A growing consensus across otherwise disparate perspectives on perception and action is that visually guided postural control emerges from within task constraints. Task constraints generate physiological fluctuations across various parts of the body. These fluctuations foster exploration of the available sensory information. For instance, standard deviation (SD) and temporal correlations of bodily sway can indicate how richly postural control samples available mechanical and visual information. Too much or too little SD entails destabilization of posture. Temporal correlations show a similar relationship, but they have also been shown to support carrying sampled information to other aspects of the postural system. The present study shows that increasing visual constraints on posture reveals an adaptive relationship between SD and temporal correlations of postural fluctuations. In short, changing the viewing distance of a fixation target shows that temporal correlations self-correct themselves across time and diminish SD across time as well. Notably, these relationships were strong for all viewing distances except the most comfortable viewing and reaching distance. This self-correcting relationship allows the visual layout itself to press the postural system into a poise for engaging with objects and events in the surrounding.
bioRxiv Subject Collection: Neuroscience


The program's purpose is to provide the learner with knowledge and understanding of the fundamental management skills, behavior, and attitudes required to manage and lead laboratory teams towards achieving goals.
Hanine is a professional engineer with 16 years of experience managing numerous multidisciplinary projects. She has a keen focus on systems and procedures and manages projects driven by performance. She embraces change as an opportunity to succeed. With that mentality, she has often been put in the role of superuser or trainer for the implementation of new or improved systems.
This module introduces the changing laboratory environment, and presents the application of different management approaches in two laboratory scenarios.
This module provides a comprehensive understanding of the 6 basic management functions and its application in the laboratory environment.
This module will uncover key characteristics that will equip managers to handle situations and lead teams effectively.
This module summarizes the management fundamentals and key characteristics required to manage confidently and competently.


For many managers, it is impossible to stop working when the clock strikes five. Instead of wasting your evenings and weekends hunched in front of a laptop or worrying about unfinished tasks, employ one or more work/life balance tactics to ensure separation. In doing so, you'll be a more effective manager and a more present spouse, parent and friend.
The first step in creating a comfortable work/life balance is improving your time management systems. When you spend the day feeling rushed and slightly behind schedule, it is more challenging to leave the office with a sense of accomplishment and peace. To help, schedule 10-minute buffers on either side of each meeting or scheduled activity. These small chunks of time will give you time to think, reflect and transition to the next task without feeling overwhelmed.
Managers are often overloaded with employee requests, meetings and supervisory activities. As the person in charge, you may feel obligated to handle everything yourself — usually, at the sacrifice of work/life balance. Instead, become a master of prioritization and delegation. Go through your list of outstanding tasks and mark those that can only be handled by you. Delegate all other tasks to your assistant or other employees on your team. Then, arrange the remaining tasks in order of importance and deadline. In doing so, you won't need to spend time at home worrying about a crucial task that went unfinished.
During the day, many professionals are easily distracted by phone calls, emails and visiting co-workers. Each interruption kills productivity and puts you farther behind, which leads to poor work/life balance. If you're finding it difficult to focus, Forbes magazine suggests using your phone alarm to mark the end of the task at hand. Pick the most important project on your list, set the alarm for one hour in the future and get to work. Alternatively, instead of checking your email every five minutes, set an alarm for every two hours to indicate a dedicated email break. Alarms can eliminate the worry about missing meetings or losing track of time, so you can stay focused and improve overall time management.
For many professionals, mental preoccupation is the major challenge of achieving a healthy work/life balance. On busy or stressful work days, it can be difficult to transition from work to home; as a result, you end up worrying about a client over dinner or struggling to solve a management problem as you're falling asleep. To change your mindset from professional to personal mode, it can be helpful to create a small ritual at the end of each day. Do a five-minute mediation on the train or sitting in your car — close your eyes, let go of all thoughts and focus on your breath. You can also distract your mind by watching a short television show, reading a chapter of a favorite book or stopping to have a cocktail with friends. If you're a fan of fitness, go straight from work to the gym; an intense workout is an excellent way to clear your head.
It takes time to accomplish a comfortable work/life balance, particularly if you've spent years in workaholic mode. However, when you make an effort to leave work at work, you'll be a better manager and a happier person.
(Photo courtesy of David Castillo Dominici / freedigitalphotos.net)


To Participate: Tweet a photo of you and your daughter, granddaughter, niece, cousin, etc., with the hashtag #shesinnocent.
In response to a new study from the Georgetown Law Center on Poverty and Inequality turned its attention to society’s perception of black girls and reported that “black girls were more likely to be viewed as behaving and seeming older than their stated age,” they also find that this dynamic is in place for girls as young as 5 years old.


The hydrogenation and oxide formation behavior of Fe-Ni-based metallic glasses (MGs), where measurements by the conventional gas-solid reaction method are difficult, is analyzed by a two-step approach: chronoamperometry followed by cyclic voltammetry (CA + CV). We introduce a concept of effective volume by measuring the thickness of the region where the hydrogen and hydroxyl ion interactions with Fe-based MG take place, which is characterized by high-angle annular dark-field scanning transmission electron microscopy. A very constant film thickness influenced by the OH- and H+ is confirmed by TEM, where the chemical homogeneity is maintained within this region. The weight percent of hydrogen and the corresponding hydrogen-to-metal ratio are determined as 1.16% and 0.56, respectively. When compared to previous studies conducted by the electrochemical- permeation method, the H/M ratio is found to be an order of magnitude larger. Electrochemical impedance spectroscopy (EIS) and subsequent equivalent circuit modeling (ECM) of the tested ribbons resolve the surface-diffusion processes for hydride formation and oxidation kinetics. This contribution provides a different perspective for the design and study of low-cost and high-performance amorphous nanofilms for hydrogenenergy applications, particularly when the common gas-adsorption methods are problematic.


Establishing a culture of sound business ethics within an organization is challenging, to say the least. Companies that market products that are not considered to be “healthy” for consumers have additional challenges. Using the online library, research a company that markets “unhealthy” products. Examples might include tobacco or alcohol companies but these examples are not all-inclusive. Respond to the following questions.
1. Briefly describe the company and its product and the ethical dilemma associated with the production and distribution of its products.
2. Describe how the perception of the product differs within cultures both within the United States and globally.
3. How has this company handled the ethical implications of its product with a focus on social responsibility, integrity and
business ethics?
4. Explain how leadership within the organization can instill a culture of ethics within the marketing department as they
strive to advertise a product that is not healthy for the customer.
Your response should be a minimum of two double-spaced pages not including the title and reference pages. You are required to use at least one peer-reviewed source. Referenced sources must have accompanying in text citations complying with APA guidelines.


Diabetes pathology derives from the combination of hyperglycemia and hypoinsulinemia or insulin resistance leading to diabetic complications including diabetic neuropathy, nephropathy and retinopathy. Diabetic retinopathy is characterized by numerous retinal defects affecting the vasculature and the neuro-retina, but the relative contributions of the loss of retinal insulin signaling and hyperglycemia have never been directly compared. In this study we tested the hypothesis that increased retinal insulin signaling and glycemic normalization would exert differential effects on retinal cell survival and retinal physiology during diabetes. We have demonstrated in this study that both subconjunctival insulin administration and systemic glycemic reduction using the sodium-glucose linked transporter inhibitor phloridzin affected the regulation of retinal cell survival in diabetic rats. Both treatments partially restored the retinal insulin signaling without increasing plasma insulin levels. Retinal transcriptomic and histological analysis also clearly demonstrated that local administration of insulin and systemic glycemia normalization use different pathways to counteract the effects of diabetes on the retina. While local insulin primarily affected inflammation-associated pathways, systemic glycemic control affected pathways involved in the regulation of cell signaling and metabolism. These results suggest that hyperglycemia induces resistance to growth factor action in the retina and clearly demonstrate that both restoration of glycemic control and retinal insulin signaling can act through different pathways to both normalize diabetes-induced retinal abnormality and prevent vision loss.


In these desperate times due to the COVID-19, During Pandemic, Muslims should follow the teachings of Prophet Muhammad (PBUH). Considering the aspects of life, Prophet’s (PBUH) steps during such crises are also ideal for us.
He (PBUH) asked us to do following things during a pandemic; Advised locals to perform the Friday prayers within the home during the heavy rain. Requested people to self-isolate during a plague. He (PBUH) asked to maintain social distancing by not leaving the current area. Ensured that the authority took care of the people’s basic needs. Cooked soup to take care of the needy. We can also; Appeal people to donate generously and open state treasury for poor people. Find volunteers to help the people to get the necessary items. Counsel people to adopt hygiene rules in their routines. Prophet Muhammad (PBUH) never limited anyone to keep washing their hands five times every day when performing ablution. However, He (PBUH) recommended performing overall physical cleanliness. Purifying the way of living:
As the verse mentioned above states, our beloved Prophet Muhammad (PBUH) used to frequently encourage the Muslims to maintain measures of prevention in order to boost their immunity. In the past, few contagious diseases already took place.
In such cases, He (PBUH) always guided the believers of Allah to stay isolated. Also, if someone’s death took place because of the disease, He (PBUH) encouraged them to follow the rituals of burying on the spot.
It is also believed that at the time of emergencies, for instance, a war, He (PBUH) buried a lot of dead soldiers without giving them the regular washing and shrouding in order to complete the process quickly.
Recalling the creator:
Yet, our Holy Qur’an states that;
The last messenger of Allah (PBUH), always emphasized and gave importance to: Upbring a responsible acquaintance who can become the origin of frequent betterment for everyone. Contribute to the current knowledge for benefiting humanity. Leaving behind charity to assist the poor and needy people.


Abstract
Childhood spontaneous bladder rupture is an uncommon event, usually associated with bladder augmentation. Occasionally it occurs in normal bladders or non-augmented bladders with a predisposing factor. We present a unique case of misdiagnosed spontaneous bladder rupture in a non-augmented bladder exstrophy patient without evidence of lower urinary outlet obstruction. His acute abdomen mimicked appendicitis and was managed with laparoscopic exploration, intraperitoneal fluid drainage, appendectomy and bladder drainage. This case highlights the need for pediatric urological consultation by surgeons in the case of an acute abdomen with free fluid in a patient with an abnormal bladder.
Keywords Acute abdomen Bladder exstrophy Bladder rupture Urinary ascites ASJC Scopus subject areas Pediatrics, Perinatology, and Child Health Urology


How does pregnancy impact iron levels?
During pregnancy, the volume of blood in your body increases by about 30-50%. Iron needs are increased because the body uses iron to make extra blood to transport oxygen for the mother and baby during this time.
Dietary iron requirements can increase to as much as 30mg per day of iron during pregnancy, especially in the second and third trimesters. This may mean supporting a healthy diet with iron supplements when daily iron needs cannot be met through diet alone.
However, food supplements are not a substitute for a varied diet and a healthy lifestyle. Also, you should not exceed the recommended daily supplement dose of iron without consulting your doctor or pharmacist.


According to the Department of Health and Human Services’ (HHS) 2012 Annual Rate Review Report, an ACA provision requiring insurance companies to justify rate increases above a certain threshold has slowed the rate of premium growth, resulting in $1 billion in consumer savings. A separate ACA medical loss ratio provision that limits insurance company spending on administrative costs has resulted in $1.1 billion in rebates to consumers, HHS announced.


Abstract
Urea Transporters are a family of membrane channel proteins that facilitate the passive transport of urea across the plasma membrane. UTs are divided into two subgroups, UT-A and UT-B. UT-As are primarily located in renal tubule epithelia and UT-Bs are highly expressed in renal descending vasa recta and extrarenal multiple tissues. Various urea transporter knockout mice exhibit low urine concentrating ability, which suggests that UTs are novel diuretic targets. With highthroughput screening of small molecule drug-like compound libraries, various potent UT inhibitors with IC50 at nanomolar level were identified. Furthermore, selective UT inhibitors exhibit diuretic activity without disturbing electrolyte and metabolism balance, which confirms the potential of UTs as diuretic targets and UT inhibitors as novel diuretics that do not cause electrolyte imbalance. This review article summarizes the identification and validation of urea transporter as a potential diuretic target and the discovery of small molecule UT inhibitors as a novel type of diuretics. UTs are a potential diuretic target. UT inhibitors play significant diuresis and can be developed to diuretics without disturbing electrolyte balance. Copyright© Bentham Science Publishers; For any queries, please email at [email protected]


Consumer Label Compliance Consumer labels are meant to be seen by potential customers in retail and online purchase settings.
Regulation for consumer labels typically apply to chemical products that can be purchased at retail locations for personal or household use such as household cleaners, air fresherers, detergents, paints, lubricants etc. Regulations for these products not only differ by product and location, these regulations often differ from industrial regulations, and require a separate review(s).
For products in the United States of America we offer a
CPSC (consumer product safety commission) label review service. For products in Canada we offer a CCCR (Consumer Chemicals and Containers Regulations) label service. For products in other locations, contact us for more details.
Nexreg’s Experts recommend reviewing each consumer label individually to ensure compliance for import and export. Contact us today!


2018 CSDMS meeting-012
"4) EarthLab" is not in the list (1) Downscaling climate models for regional applications, 2) Dakota, 3) ANUGA, 4) Artificial Intelligence & Machine Learning, 5) Will not attend a clinic) of allowed values for the "CSDMS meeting select clinics3 2018" property.
Browse abstracts
Towards a Quantitative Understanding of Parameters Driving Submarine Slope Failure: A Data Mining and Machine Learning Approach Jeffrey Obelcz, Naval Research Lab Stennis Space Center Mississippi, United States. jbobelcz@gmail.com Naval Research Lab Stennis Space Center Mississippi, United States. warren.wood@nrlssc.navy.mil
Submarine slope failure is a ubiquitous process and dominant pathway for sediment and organic carbon flux from continental margins to the deep sea. Slope failure occurs over a wide range of temporal and spatial scales, from small (10e4-10e5 m3/event), sub-annual failures on heavily sedimented river deltas to margin-altering and tsunamigenic (10-100 km3/event) open slope failures occurring on glacial-interglacial timescales. Despite their importance to basic (closing the global source-to-sink sediment budget) and applied (submarine geohazards) research, submarine slope failure frequency and magnitude on most continental margins remains poorly constrained. This is primarily due to difficulty in 1) directly observing events, and 2) reconstructing age and size, particularly in the geologic record. The state of knowledge regarding submarine slope failure preconditioning and triggering factors is more qualitative than quantitative; a vague hierarchy of factor importance has been established in most settings but slope failures cannot yet be forecasted or hindcasted from a priori knowledge of these factors.
A new approach to address the knowledge gaps outlined above is using machine learning to quantitatively identify triggering and preconditioning factors that are most strongly correlated with submarine slope failure occurrence. This occurs in three general steps: 1) compile potential predictors of slope failure occurrence gridded and interpolated at desired resolution, 2) compile predictands (specific values that we wish to predict), and 3) recursively test predictor/predictand correlation with observed data until the strongest correlations are found. Potential predictors can be parsed into categories such as morphology (gradient, curvature, roughness), geology (clay fraction, grain size, sedimentation rate, fault proximity), and triggers (seismicity, significant wave height, river discharge). Predictands (i.e. training data) are various proxies for slope failure occurrence, including depth change between bathymetric surveys and sediment shear strength. The initial test sites are heavily sedimented, societally important river deltas, as they host both frequent slope failures and ample predictor/predictand measurements. Once predictors that strongly correlate with submarine slope failure occurrence are identified, this approach can be applied in more data-poor settings to further our current understanding of global submarine slope failure distribution, frequency, and magnitude.


Information technology services are needed by all companies. A wide range of IT hardware and software solutions are used by businesses and organizations. External support services may be needed to manage these setups. The services are needed if there is no internal IT team to handle such jobs or such a team is not capable of handling the tasks at hand. The company offering IT management services offers a wide range of services. The types of services such a company offers depend on its specialty. For example, a company may offer only IT hardware repair services while another one may offer only software related services.
These companies can offer support services for IT asset management, performance management, security, troubleshooting, diagnostics, system repair, administration and remote monitoring, among others. They can help install all types of IT hardware and software setups. They have specialists to install network, data backup and cloud systems. Their services can be hired on per job, annual or regular basis.


Principal contributor: Hannah Breul Source:Colonial Pipeline
Following an outage that began on October 31, Colonial Pipeline’s Line 1 resumed shipping gasoline early Sunday morning. Line 1 carries gasoline from the Gulf Coast to as far east and north as North Carolina, and is a key supply source for several states in between and beyond. When operating at full capacity, Line 1 carries 1.4 million barrels per day of gasoline from the U.S. Gulf Coast to a major junction and product storage hub in Greensboro, North Carolina. Various branches provide gasoline to central and eastern Tennessee, southern Georgia and eastern and western portions of Virginia. Beyond Greensboro, other portions of Colonial’s system send gasoline, diesel and other transportation fuels to Maryland and New Jersey.
According to Colonial Pipeline, gasoline is expected to reach as far north as Charlotte, North Carolina, within a day of Line 1’s restart. Gasoline shipments on Colonial’s system are expected to reach as far north as Baltimore, Maryland, by Tuesday and to reach their northern terminus in Linden, New Jersey, near New York Harbor, by Wednesday.
Total motor gasoline stocks in the Lower Atlantic states (defined by Petroleum Administration for Defense District, or PADD, 1C) were at relatively high levels before the October 31 outage, with 27.5 million barrels, or nearly 20% above the previous five-year average, in storage as of October 28. Inventory data for the week ending November 4 will be available on Wednesday, November 9 in the Energy Information Administration’s (EIA’s)
Weekly Petroleum Status Report.
Despite the recent outage, GasBuddy, a crowd-sourced retail gasoline price comparison site, showed retail prices in most areas in the Southeast below $2.35 per gallon (g) as of November 7. EIA’s weekly retail price for regular gasoline for the Lower Atlantic (PADD 1C) was $2.17/g as of Monday, November 7, virtually unchanged from the previous week, and 6 cents/g below the national average.
A previous disruption to Line 1 flows from September 9 – September 21 resulted in record changes in motor gasoline stocks in both the Lower Atlantic states and the Gulf Coast states during the week ending September 16. During that week, total motor gasoline stocks in PADD 1C fell by nearly 6 million barrels, from 28 million barrels to 22 million barrels. Meanwhile, Gulf Coast (PADD 3) gasoline stocks increased by nearly 4.8 million barrels. In the week ending September 23, stocks grew modestly in both regions, indicating that resupply had begun to reach the Lower Atlantic region.


Linear Investments provides a summative overview on the performance of Hedge Funds in October and the first three quarters of 2019.
Hedge Funds posted the best performance this year since 2013.
According to Bloomberg hedge funds are gaining momentum, surpassing uncertainties in markets and geo-politics having gained 4.9% on average in the first three quarters of 2019. Eurekahedge Hedge Fund index similarly returned 5.7% over the same timeline with nearly 30% of the managers within the index having recorded double digit returns.
As at the end of September, Eurekahedge reported that assets under management within the hedge fund industry stood at US$2.27trillion, illustrating a performance growth of US$98.3 billion year-to-date. Leading performance for the year within the Eurekahedge Index were Global Macro and Equity Long/Short strategies, while geographically Latin America focused funds led returns. Bloomberg similarly highlighted equity strategies as leading in terms of gains, followed by event-driven strategies.
The growth has come despite a year of uncertainties roiling markets; Brexit, US-China trade war, impeachment inquiries to name but a few. Nevertheless, in the continuation of the longest bull-run in US history, hedge funds have continued to trail the S&P 500 which rallied 18.74% in the first three quarters of 2019. Whilst Eurkeahedge reports US$120.8bn in investor redemptions from hedge funds over the year, it also shows redemptions slowing with net outflows in Q3 reported as US$34.3bn versus Q1 US$46.4bn. Now in the final quarter of 2019, the challenging geo-political backdrop remains in addition to relatively unchartered monetary policy regimes and a slowing global economy.
Aranca Research Group cites that the top challenges in the hedge fund community include growing AUM, fee pressures and keeping up with regulatory change.
However, funds that are already performing well are expected to continue to capture institutional investment. This growth will be further driven by HNWIs in emerging markets. As we look to the year ahead, it will be up to investors to navigate these nuances to ensure the best returns.
Linear has always held the stance that as volatility returns to the market the Alternative area will start to strengthen in risk return patterns and become more attractive than when the market is totally directional.


The process of ending a marriage can be daunting. Even after deciding to divorce, either spouse may be overwhelmed by the thought of court hearings, custody disputes and asset division.
When a couple files for divorce in Florida, they can pursue a simplified marriage dissolution if they meet certain criteria.
Simplified divorce
With this process, the state does not require financial disclosure. However, either party can ask for disclosure during negotiation of a simplified divorce agreement. A married couple can request a simplified marriage dissolution in Florida if:
At least one spouse has lived in Florida for at least six months Both spouses agree to waive spousal support. They reach an agreement on property and debt division. They have no children younger than 18 together and the wife is not currently pregnant. Standard divorce
Couples who do not meet the above requirements must file for a standard divorce in Florida. This process requires full financial disclosure within 45 days of filing. The spouse who initiates the divorce must submit a petition that details his or her preferences for child custody, property division and spousal support as applicable. He or she must serve the other spouse with the petition along with the hearing date scheduled by the court. The responding spouse can submit his or her own petition within 20 days of receiving legal notice.
Florida may require couples who cannot agree on the key issues in divorce to go to mediation. If mediation does not prove successful in helping the couple reach a fair agreement, the judge will make a decision about contentious issues on the couple’s behalf.


DNB expects that banks understand the potential impact of climate-related risks on their balance sheets. Any material climate-related risk should be governed in a way consistent with sound risk management similar to any other type of material risk. DNB’s interpretation of how existing regulation applies to climate-related risk management is detailed in the Q&A.
DNB has assessed existing practices in the Dutch banking sector related to the management of climate-related risks. This Good Practice document aims to share some of the good practices that were observed by DNB, with the intention to inform the sector as a whole. These good practices provide non-binding guidance on how banks can organise their processes and procedures to manage the climate-related risks related to their activities.
Climate change poses new challenges to the risk management of banks. Both physical and transition risks can be characterised by significant uncertainty and nonlinearity, while their probability of occurrence may not be reflected in historical data. These challenges thus warrant timely and concerted actions by banks, but also by the wider private and public sector.


Know where your food comes from. Our 2019 weekly share list.
Helping The Community
Organic Local CSA produce contains fewer pesticides and chemicals such as fungicides, herbicides, and insecticides are widely used in conventional agriculture, and residues remain on (and in) the food we eat. Organic food is often fresher because it doesn't contain preservatives.
CSA's are good for your health, community, and environment.


@MISC{Dhenesh_observationsof, author = {Virallikattur S Dhenesh and Elena Sitnikova and Jill Slay}, title = {observations of team meetings in organisations}, year = {} }
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Abstract
Teams collaborate in different contexts within organisations to share information with its members in achieving their targets. Collaborations with face-to-face meetings are prevalent despite the emergence of numerous tools to support distributed team collaborations. However, the nature of tool-support for team collaborations in the last decade was focused on supporting distributed and web-mediated meetings. Furthermore the tools were either not designed to support all the processes within team collaboration or not readily adopted by users. Literature on developing an integrated tool-support that includes all the potential processes within a meeting, and learning lessons whilst designing tools to improve the state of their adoption is largely unexplored. This paper reports on a qualitative study that observed twenty team meetings from five organisations in South Australia and analysed the data using a grounded theory approach to generate stories on team activities. The stories were used to develop a tool-kit framework and lessons on providing a tool support for team meetings. The proposed framework consists of a list of potential hardware and software tools that could be introduced within a team meeting to support the team activities.Lessons were learned on the potential processes that would require tool support, participants ’ requirements and how technology


Thursday, March 9, 2017, 6:00 PM | Leave Comment
Bankruptcy affords those in significant financial distress a clean start. However, the fact of bankruptcy remains on your credit history for up to a decade.
If you seek to avoid the harm to your credit and ability to buy a home or other major ticket items, consider these tips to suppress your debt burden.
No Substitute for Cash
Relying on
credit for staplesand regular living expenses can unnecessarily increase your debt load.
Credit card debt should not pay for disposable items such as groceries or most restaurant trips.
When you turn to credit for these purchases, you face interest charges for items things with little or no repetitive use and that no longer exist.
Use cash or your checking account for electric, gas, water, garbage, cable and other regular monthly bills.
Getting Financially Lean
If you find money tight, consider eliminating certain services.
For instance, consider removing data plans from your smartphone and tablets and using Wi-Fi at your home or at establishments that offer it free of charge.
Reduce monthly payments by downgrading or eliminating satellite or cable television or satellite packages, especially those with channels you don’t watch.
Above and Beyond
Pay more than the minimum payment. Consumer Reports states that it would take you
24 yearsto wipe out a $2,000 balance on an 18-percent credit card if you paid only two percent per month.
Extra payments on small balance credit cards can reduce your interest outlays on especially high-interest cards.
Alternatively, devote extra amounts to the lower-balance accounts and reserve minimum payments for the high-balance cards.
Using tax refunds can make a significant dent in your debt. As you pay off cards, you’re credit score may increase because zero-balance accounts equate to more available credit.
Home Equity Loan
With a home equity loan, you borrow against your home’s value, less what you already owe on it.
Using the home equity loan proceeds, you pay off existing credit cards, medical bills and other unsecured debt.
Further, the lower interest rate on a home equity loan replaces the higher interest rates on your credit cards.
However, a home equity loan effectively converts unsecured credit to a secured loan. If you miss payments, you could lose your home to foreclosure.
Credit Counseling
Find a reputable credit counseling agency that can help examine your credit condition, negotiate for lower rates and consolidate your credit cards, student loans, medical bills and other unsecured debt.
In a debt management plan arranged through a credit counselor, you deposit an amount monthly with the agency. With your deposit, the agency pays these creditors according to a set plan. Depending on the plan or creditor, you may avoid late fees or interest.
Consult your state’s Attorney General’s office, a consumer protection organization or an agency on the United States Trustee Program’s approved pre-bankruptcy counseling list.
If bankruptcy is your last resort against mounting debt, contact an attorney like
Lazaro Carvajal who can guide you through the procedures and requirements for getting your debt discharged. Throw us a like at Facebook.com/doable.finance


Companies based in the Philippines, the government, and the academe recently met to discuss the implications of the future of work. The
Future of Work Symposium, organized by Austrade Manila on behalf of Macquarie University in Makati city, provided a platform for all involved to discuss issues challenging businesses undergoing digital transformation. Issues included meeting supply of needed skills in the new workforce; concerns related to staff hiring, on-boarding and training; massive job losses due to automation; and the increasing need for lifelong learning.
Participants of the event included high-level representatives from the Philippine government, private and academic sectors, Australian businesses, business process outsourcing firms, and multinational companies located at the Clark Freeport and Economic Zone.


It is often thought that young children are incapable of understanding transgender and nonbinary identities, but this is untrue. Additionally, "No harm is done on an individual or societal level if a child has the option of exploring their gender identity from early on," even if the child later turns out to be cisgender.[1]


X-linked Charcot-Marie-Tooth (CMTX) disease is a common inherited degenerative disorder of the peripheral nerve. Previously, our laboratory identified a large New Zealand/United Kingdom (NZ/UK) family mapping to the CMTX3 locus (Xq26.3-27.1). We have now identified a second large, Australian X-linked CMT family that links to the CMTX3 locus. This new family has the same phenotype as our previously described CMTX3 family, with slightly milder disease in males than CMTX1 and asymptomatic carrier females. This study also includes the re-analysis of one of the original US pedigrees reporting the CMTX3 locus. The large Australian family shared the complete disease haplotype with our original NZ/UK family, while the American family shared only the distal portion of the disease haplotype. Comparison of the frequency of the CMTX3 haplotype to the normal population showed strong statistical evidence (p < 0.0001) indicating that the smaller shared haplotype is identical by descent. This suggests that the new CMTX3 family, our previously reported family, and the original American CMTX3 family have a common ancestor, and the disease in these families is caused by a founder mutation. The ancestral recombination observed in the American family refines the CMTX3 interval to a 2.5 Mb region between DXS984 and DXS8106. In this region, 11 out of the 15 annotated genes have been excluded for pathogenic mutations.


Purpose: The aim of this meta-analysis and systematic review was to determine whether bleeding prophylaxis benefits patients after colonoscopic polypectomy. Methods: A systematic review of the literature was performed to find prospective randomized controlled trials of postpolypectomy hemorrhage prophylaxis. Studies were selected according to specific criteria and analyzed to generate pooled data. Results: Eight studies encompassing 2,595 polyps met the criteria for the meta-analysis. The rate of early bleeding was significantly decreased relative to the control when a single prophylactic technique was used [2.58% vs. 8.15%, OR = 0.34 (95% CI, 0.20-0.58), P < 0.0001]. The use of multiple prophylactic techniques resulted in a lower early postpolypectomy hemorrhage rate compared with the use of a single prophylactic technique [0% vs. 8.41%, OR = 0.12 (95% CI, 0.03-0.47), P = 0.002]. The late bleeding rate did not differ significantly between the monotherapy and control groups [0.61% vs. 1.39%, OR = 0.37 (95% CI, 0.11-1.28), P = 0.12], and the use of combined preventative techniques did not significantly decrease the late postpolypectomy bleeding (PPB) rate compared with use of a single prophylactic method [1.43% vs. 2.05%, OR = 0.70 (95% CI, 0.32-1.55), P = 0.38]. Conclusion: Prophylactic endoscopic treatments are effective at reducing early PPB after colonoscopic polypectomy. However, patients with late PPB may not benefit from bleeding prophylaxis.


With more stringent health and safety legislation, utilities need to identify, assess, and control workplace risks. Lone worker safety has become a focus across utility organisations, with many staff travelling long distances, driving vehicles after hours, and undertaking maintenance and development of utility infrastructure in hazardous environments.
Across Australia and New Zealand, the shift to privatised utility networks, expanding infrastructure, growing populations and tightening margins are driving the need to optimise operational efficiencies and effectiveness, while managing risk. Ensuring better, more affordable customer outcomes requires maximising the productive utilisation of existing organisational fleet and assets. Sharing resources and improving transparency are two ways to achieve this.


Abstract
A study was conducted to understand the three steps of the NF-κB pathway, IκB degradation, processing of NF-κB precursors, and activation of IKK and other kinases. The study also highlighted how deubiquitination enzymes negatively regulate the NF-κB pathway and how dysfunction of these enzymes lead to human diseases. It was observed that NF-κB pathway provided an understanding of roles of ubiquitin in cell signaling including signal-dependent degradation of an inhibitor that further lead to a rapid activation of a signaling cascade, limited proteolysis of a precursor protein by the proteasome, and activation of protein kinases. The ubiquitin system played a significant role in diverse signaling cascades leading to NF-κB activation. The study also concluded that pervasive role of ubiquitin in NF-κB pathways showed the regulatory potential of ubiquitination and deubiquitination.
ASJC Scopus subject areas Chemistry(all)


Description
Cystone naturally promotes a healthy urinary tract and helps maintain normal urine composition and mucosal integrity. It is a natural aid in maintaining healthy water management and relieves temporary water – weight gain.
BALANCES PH OF URINE: It manages the production and composition of urine, thereby balancing its pH, which is often a cause for UTI’s and the burning sensation while emptying your bladder.
HELPS REDUCE STONE FORMATION: Cystone works by managing the concentration of calcium salts in the blood, which contributes to the formation of stones, and aids in breaking them down and expelling them from the body. It does this by acting on mucin, the sticky substance which binds the particles together to form stones. NATURAL DIURETIC: Cystone naturally increases the excretion of excess water from the body, thereby increasing urine production and reducing bloating. This reduces the chances of you catching repeat urinary infections. ALL NATURAL SUPPLEMENT: As it is made of natural ingredients based on Ayurveda, Cystone does not exhibit any side effects as long as the recommended dose and use is not exceeded.


Norwegian Cruise Line, based in Miami, is one of the most innovative companies operating in the cruise industry. As part of their commitment to the environment, Norwegian Cruise Line applied biocide free, Intersleek foul release coatings to the 78,309 GRT Norwegian Sun when it was built in Germany in 2001.
Ten years later, the Intersleek
® system has only needed touch-up repairs, significantly reducing overall paint volume, packaging, waste and VOC emissions. Because full coats were not necessary, dry-docking time and costs were also significantly reduced.
During Norwegian Sun’s dry dock in the Bahamas in January 2011, it was noted that the Intersleek® system had performed well and was in good condition with no animal or weed fouling. Commenting on the performance of the Intersleek
® system, Mr. Brian Swensen, Senior Vice President, Technical Operations, Norwegian Cruise Line said, “We are very pleased with the performance of the Intersleek ® system. At Norwegian Sun’s two interim dry-docks, we only applied a total of 600 litres of Intersleek®. For a standard antifouling system, we would have used approximately 6,000 litres. This has resulted in a 90% reduction in VOC emissions and a 100% reduction in biocide release. The fact that no full coats were required meant that the dockings in 2004 and 2007 were completed ahead of schedule with lower paint and application costs than expected.”
Intersleek
® has now been applied on more than 500 passenger vessels over the last 15 years, including 100 cruise vessels. Many of these vessels have achieved significant efficiency improvements with reduced environmental impact.


Coat tight-fitting metal parts, such as gears, clutches, and press-fit assemblies, with these lubricants before sliding them together to make assembly easier. Once assembled, they provide initial lubrication in equipment before oil has a chance to flow.
Mineral-oil-based lubricants, derived from petroleum, are more economical than synthetic-oil-based lubricants. Lubricants with zinc prevent corrosion.
Lubriplate No. 105 is often used to assemble motor and engine components. It has excellent moisture resistance.