{"content": "The Council reviewed an initial review draft of an action that evaluated the potential impacts of: 1) a registration requirement for unguided halibut rental vessels and 2) aligning bag and size limits of unguided anglers using rental vessels to harvest halibut with those of charter anglers in IPHC Regulatory Areas 2C and 3A. After reviewing the analysis, reports from the Charter Halibut Management Committee and Enforcement Committee, and public testimony, the Council moved to take no further action on this item.\nThis action was proposed to address concerns that, in addition to the differences in harvest regulations between charter (guided) and unguided recreational halibut anglers, growth of the rental boat segment of the unguided sector may negatively impact other halibut fishing sectors. The analysis provided a description of status quo recreational halibut management, trends in subarea harvest in the recreational halibut fisheries, and minimum estimates of the number of rental vessel businesses in Areas 2C and 3A. It also outlined existing vessel registration programs and the extent to which they could satisfy the Council’s purpose and need for the action. The initial review draft outlined management and enforcement considerations of the proposed action alternatives, highlighting administrative costs of a registration requirement and logistical details that would benefit from Council clarification.\nGiven the lack of existing data on the unguided halibut rental vessel subsector, and the potential costs of implementing regulatory solutions to gather those data, the Council requested that staff coordinate with the Alaska Fisheries Science Center, Alaska Department of Fish and Game, NMFS Alaska Region, and recreational stakeholders to explore alternative non-regulatory methods to quantify the number and geographic scope of unguided rental boat activities in recreational halibut fisheries off Alaska. The Council acknowledged the importance of gaining more information on the unguided halibut rental vessel subsector, but noted that this proposal was not likely to be an effective method to do so. The Council encouraged participation by the recreational sector in upcoming efforts to gather this information.\nStaff contact is Sara Cleaver.", "pred_label": "__label__POS", "pred_score_pos": 0.892773449420929}
{"content": "Penetrants and multipurpose lubricants perform a wide variety of lubricating and cleaning tasks. They are highly viscous substances that penetrate tight spots where other oil and grease are difficult to apply. They are ideal for loosening rust, tar, dirt, and corrosion and can be used to free moving parts and equipment as they lubricate.", "pred_label": "__label__POS", "pred_score_pos": 0.6432678699493408}
{"content": "Stakeholder\nThroughout the UK, the need to consult local communities on planning applications remains a crucial part of any development, as resident voices are given increasing merit at all levels of government.\nStakeholder Relations\nAcross all of our offices, we work with clients to engage with stakeholders, manage any concerns, and identify opportunities to cultivate positive relationships, no matter how big or small the project is.\nWe understand that engagement is not “one size fits all”. Tailored programmes that use both traditional methods, such as face-to-face meetings and public exhibitions, as well as more innovative tools, including our online consultation software ‘Mapdragon’, provide comprehensive communications strategies to engage with local communities at all levels, where possible securing proposals that benefit from local support, likely resulting in a smoother process through to a decision committee.\nWe’ve compiled large and small communications plans with a range of simple and complex activities, using techniques ranging from large-scale roadshow events for strategic land in the Green Belt, knocking on neighbour’s doors for small developments in urban areas, and hosting specific issue-based workshops with key stakeholders and interested parties. We have also hosted wholly online consultation with opportunities for participation with hard to reach groups. Each has its place as part of a bespoke programme.", "pred_label": "__label__POS", "pred_score_pos": 0.9973231554031372}
{"content": "Extracellular RNAs (exRNAs) are a type of RNA molecules that present in various biological fluids. exRNAs are heterogenous populations including small (e.g., miRNA) and long non-coding RNAs and coding RNAs (e.g., mRNA). They can exist in a free form or associate with carriers range from lipo- and ribo-proteins to extracellular vesicles such as exosomes in the extracellular fluids. exRNAs participate in cell-to-cell communication to regulate a broad array of physiological and pathological processes. exRNAs have been widely studied as a biomarker for cancer and other diseases. Researchers at Sungkyunkwan University discuss the sorts of exRNAs with potential carriers as well as their roles in cancer.\nExtracellular RNA: Emerging roles in cancer cell communication and biomarkers. Cancer Letters[online ahead of print]. [abstract]", "pred_label": "__label__POS", "pred_score_pos": 0.9655821919441223}
{"content": "The tax gap is an estimate of the difference between the amount the ATO collects and what we would have collected if every taxpayer was fully compliant with tax law. No tax system can eliminate tax gaps. Our goal is to sustainably reduce tax gaps over time.\nIn 2017–18 the tax gap for the tax and superannuation system was estimated at approximately $31 billion or 6.9%.\nThis year sees the full release of our tax gap research program for the first time, with the release of five new gap estimates: medium business, fringe benefits, luxury car tax, alcohol, and product stewardship for oil. The previously-released gaps have been refreshed with new figures and insights. Attached a summary of the tax gaps estimates which outlines some high level information. The gaps have been published in line with the Australian Taxation Office 2019-20 Annual report, which is now available for you to view or download at ato.gov.au.", "pred_label": "__label__POS", "pred_score_pos": 0.5970518589019775}
{"content": "During the past couple of years there has been significant progress in our understanding of the development of different lineages of T cells within the thymus. Pathways, subpopulations and cellular dynamics are all becoming clearer. Signal transduction through primary and accessory receptors is also beginning to be understood. However, the exact nature of the events that lead uncommitted cells to choose a particular lineage (either alpha beta/gamma delta or CD4+/CD8+) has still not been determined.", "pred_label": "__label__POS", "pred_score_pos": 0.9029045104980469}
{"content": "We know the law. We are good at it. And we truly care about our clients. What can we do for you?\nA criminal record follows you wherever you go. Even an arrest record — with no conviction — can prevent you from obtaining ideal employment, loans, housing and other favorable opportunities. However, laws allow certain criminal arrests, charges and convictions to be wiped clean from your record once you become eligible for expungement in PA.\nWhen a record is expunged, it is no longer available to the public or to employers, potential employers, insurance companies and others. The arrest will not show up on criminal background checks.\nA part of our criminal practice includes defending clients facing first-offense DUI charges, and getting them approved for Accelerated Rehabilitative Disposition (ARD). The ARD program is a diversionary program that allows someone who is arrested on a DUI charge to avoid being convicted, and allows any remaining records related to the DUI case to be expunged, such as the arrest record and the record of the charges being filed.\nThe district attorney and the Pennsylvania State Police Central Repository maintain a list of people who have participated in a diversionary program to determine if a person is eligible for ARD, since a participant is only eligible once for a diversionary program.\nOther criminal offenses that may be eligible for expungement in Pennsylvania include:\nSchedule an initial consultation with our experienced criminal law attorneys if you need help getting your criminal record expungement in PA. Based in Media, Pennsylvania, we represent clients throughout Delaware County, Philadelphia County, and Chester County. Call 610-565-9696 or contact us online.\n© 2020 Berman & Associates", "pred_label": "__label__POS", "pred_score_pos": 0.7301228046417236}
{"content": "Applying materiality concepts to Environmental, Social, and Governance (“ESG”) measurement can yield statistically and economically significant alpha in a global investable universe. “Corporate Governance, ESG, and Stock Returns around the World,” by Causeway senior research analyst Mozaffar Khan, published in the Fourth Quarter 2019 issue of the Financial Analysts Journal, shares our research on the subject.", "pred_label": "__label__POS", "pred_score_pos": 0.7619723677635193}
{"content": "Developments of interest this week are outlined.\nROI IAASA has issued a Compendium of Illustrative Auditor’s Reports. IAASA has published its This thematic review explores how a sample of auditors of public-interest entities complied with the requirements of International Standard on Auditing (Ireland) 701, ISA 701 Thematic Review. Communicating Key Audit Matters in the Independent Auditor’s Report (ISA 701). IAASA has issued a Feedback Paper and revised ISA (Ireland) 315, Identifying & Assessing the Risks of Material Misstatement. The Central Bank of Ireland has released its Quarterly Bulletin No. 4 for 2020.\nUK The Financial Reporting Lab of the UK Financial Reporting Council (FRC) has released guidance covering some critical areas of focus for 2020 year-ends. The FRC has this week issued three sets of amendments to UK and Ireland accounting and reporting standards. The amendments address some topical issues and maintain a necessary alignment with international standards. The FRC has launched a consultation on the proposed revision of its UK auditing standard ISA (UK) 240 (Updated January 2020) - The Auditor's responsibilities Relating to Fraud in an Audit of Financial Statements.\nEuropean", "pred_label": "__label__POS", "pred_score_pos": 0.7236560583114624}
{"content": "How It Works\nMagnesium is an essential mineral. It is present in more than 300 enzymatic systems where it is crucial for energy production and other metabolic functions. The heart, brain and kidneys cannot function without adequate levels of this nutrient. Magnesium is used in reaction to form Tri Carboxylic Acid (TCA), which aids in the cells’ energy-producing cycle. It is also involved in smooth muscle contractions, affecting the heart, gastrointestinal, urinary and female reproductive tracts.\nTake 2 capsules twice daily with meals.\nMagnesium citrate and magnesium malate.\nReviews", "pred_label": "__label__POS", "pred_score_pos": 0.6345571279525757}
{"content": "Sometimes, car accident victims are often relieved when they seem free of apparent fractures or wounds after an accident. Declining an ambulance ride to the hospital could prevent diagnoses of hidden injuries. A medical examination after a car accident is crucial, even if it confirms that there are no injuries.\nHidden injuries could include disc injuries or cervical dislocations due to the vehicle coming to a sudden stop. Fractured or cracked bones can cause long-term health problems. An example is a broken rib that punctures vital organs. Sprains, tears and strains of muscles, ligaments and tendons are typically only identified by CT scans or other equipment. These are soft tissue injuries that could become swollen and inflamed if left untreated.\nThe impact of a collision often causes whiplash injuries that cause headaches, neck and shoulder pain and stiffness, and even traumatic brain injuries, all of which can take months or years to heal. Further dangers include potential internal injuries to the kidneys, bowels, heart or aorta, lungs, liver and spleen. The severity of these injuries can only be determined by a doctor, failing which could be fatal if internal bleeding is not treated.\nLast but equally traumatic could be the psychological damage caused by a vehicle accident, even if it involves the impact of witnessing others losing their lives. If another party’s negligence caused an accident, the injured victims might pursue financial relief. An experienced personal injury attorney can provide valuable support and guidance throughout a civil lawsuit. However, medical records must accompany documented claims, and the failure to have a medical examination after the accident might jeopardize the likelihood of recovering damages.", "pred_label": "__label__POS", "pred_score_pos": 0.9662330746650696}
{"content": "Indications for creating a transjugular intrahepatic portosystemic shunt (TIPS)\nTIPS creation is frequently performed to prevent recurrent variceal bleeding related to portal hypertension.\nOther indications include refractory ascites or hepatic hydrothorax, Budd-Chiari syndrome, portal hypertensive gastropathy, and hepatorenal or hepatopulmonary syndrome.\nTIPS placement may be an effective bridge to liver transplantation for patients with end-stage liver disease and manifestations of portal hypertension.", "pred_label": "__label__POS", "pred_score_pos": 0.7680040597915649}
{"content": "HARLINGEN — “What do we make pizza out of?”\nCindy Benavides held up a bowl with a fluffy white substance.\n“Flour,” she said deliberately, teaching the pre-kindergarteners from Sam Houston Elementary a new vocabulary word.\nThe children were on a local field trip to Cici’s Pizza to broaden their experiences and build their vocabulary. Research shows first-hand experiences are crucial to teaching literacy, which includes learning more vocabulary words.\nBenavides, owner/operator of the Cici’s location, held up another object.\n“This is a ‘measuring cup,’” she said, the children repeating after her.\nShe mixed water with the flour and kneaded the mixture.\n“When we mix it we get what? A dough ball.”\nShe walked around and let the children feel the gooey dough ball that would become a pizza.\nSomeone handed her a tray with a dough ball which had been stretched to make a pizza. She then waved a wooden cylinder with little pegs sticking out. She’d use it to poke holes in the pizza dough to let the air escape. But what was this utensil called?\n“A hammer,” said a young boy.\n“It’s a docker,” Benavides said. “Now do you know how to make pizza?”\n“No,” the children answered.\n“I haven’t shown you everything yet,” she said. “What is this?”", "pred_label": "__label__POS", "pred_score_pos": 0.5557296276092529}
{"content": "When our heart is in a holy place,When our heart is in a holy placeWe are blessed with love and amazing grace,When our heart is in a holy place. ~ hymn lyrics by Joyce Poley\nOne of the five pillars of Islam is the requirement that, at least once during every adult Muslim’s lifetime, if they are able, a pilgrimage to the Holy Land of Mecca must be carried out. This ritual journey is representative of Muslim solidarity and devotion to Allah. The five day period of Hajj this year began yesterday.\nMany of the world’s religions encourage undertaking a pilgrimage to a holy destination as a way of deepening one’s connection to their faith and with the Divine. The ritual of embarking on a physical journey to a sacred place can be both inspirational and transformational.\nThe labyrinth is seen by some as symbolic of a religious pilgrimage. It is speculated that the one at Chartres Cathedral in France has been considered as such, as early at the 13\nth century. Walking the winding-yet-defined path toward a single destination, one has the opportunity to connect with Spirit, allowing oneself space and time to listen for the voice of God… If you are open to fully embracing the experience of it, the labyrinth can indeed be a holy place.\nMany of us make our own annual pilgrimage, although we may not consider it as such. Do you travel for Thanksgiving, to break bread with extended family? At Christmas, to visit a beloved grandchild? During the summer, to a favorite destination – perhaps the mountains or the shore? Although not prescribed by any chosen religion as\nnecessary, these, too, are journeys that serve to nourish our souls and fulfill a spiritual need within us. These, too, are “holy” destinations.\nIs there a physical location that fills this need for you; somewhere that resonates personally as a sacred, holy place? When your heart is in a holy place, where are you apt to find yourself, geographically?\n~ Christiana", "pred_label": "__label__POS", "pred_score_pos": 0.5198736786842346}
{"content": "Progress on avoidance, guidance and displays By Erik Theunissen and Brandon Suarez|December 2016 The Digital Avionics Technical Committee advances the development and application of communications, navigation, and surveillance systems used by military and commercial aircraft.\nOn the long road to allowing unmanned aircraft full access to the National Airspace System, 2016 was a pivotal year for achieving important milestones in the area of sensors, algorithms, displays, flight testing and development of the minimum operational performance standards.\nFor unmanned aircraft to meet the intent of the International Civil Aviation Organization’s Annex 2, a technical solution is being developed to enable a detect-and-avoid, or DAA, capability. RTCA’s Special Committee 228, or RTCA SC-228, is developing a technical standard for airborne and ground-based equipment that will aid remote pilots in remaining well clear of and avoid collisions with other airspace users. Using a variety of sensors, such DAA equipment will detect cooperative as well as noncooperative intruder aircraft and provide pilots with aural and visual guidance for remaining well clear. One of the key features of the “Phase I” system SC-228 is codifying the alerting and guidance that the remote pilot will receive to avoid a future loss of “well clear.”\nIn anticipation of future alerting, guidance and display requirements for DAA, General Atomics Aeronautical Systems started the development of the Conflict Prediction and Display System in 2009. The guidance functionality embedded in CPDS is based on the mathematical foundation developed by researchers at NASA’s Langley Research Center in Virginia for conflict prevention algorithms. Initially, many CPDS design requirements followed from RTCA DO-317B, but the community was still working on agreement of key aspects, such as the definition of “well clear.” As the minimum operational performance standards matured during 2015 and 2016, CPDS was updated in terms of alerting and guidance functions and display. Questions on draft alerting and guidance criteria related to minimum operational performance standards have been addressed, in part, using flight tests.\nA key question for alerting and guidance concerns the interoperability with the existing traffic collision avoidance system, or TCAS. To address this question, dedicated multi-intruder conflict geometries have been designed that are aimed at triggering both DAA and TCAS alerts, as well as encounters that should only trigger DAA alerts. Initial analysis was performed using simulations to gather baseline data. An important milestone in 2016 was the gathering of data for such encounters during actual flight. The data was collected as part of the NASA-led series of flight tests known as “Flight Test 4.” These DAA system flight tests included collaborative contributions from the FAA, NASA, Honeywell, General Atomics and BAE Systems. The prototype DAA system used in these flight tests included a surveillance suite comprised of a TCAS providing active transponder-based surveillance, a transponder capable of ADSB-In and a General Atomics-designed air-to-air radar for DAA.\nA Honeywell-developed surveillance algorithm produces a single track onboard the aircraft, which is then downlinked to the ground control station using satellite communications. NASA’s Ikhana unmanned aircraft system has been used as the primary test vehicle, and several Honeywell and NASA aircraft have been intruders. Using encounter geometries with up to four closely spaced intruders, the capability of the new DAA radar to distinguish between different tracks on a timely basis was demonstrated in June 2016.\nA key capability for the 2016 flight tests was a real-time view of the behavior of the DAA alerting parameters, which significantly contributed to determining whether an encounter had been executed accurately.\nThe DAA minimum operational performance standards are in their final phase of development and were to be published by the end of the year. Meanwhile, the CPDS has been extended to be compatible with the latest version of the FAA’s Airborne Collision Avoidance System for Unmanned Aircraft to begin to address “Phase II” capabilities within RTCA SC-228 and SC-147. ★", "pred_label": "__label__POS", "pred_score_pos": 0.5361549258232117}
{"content": "Abstract Preview\n1.1 This document specifies requirements and gives recommendations on the management of integrity of a pipeline system throughout its life cycle which includes design, construction, commissioning, operation, maintenance and abandonment.\n1.2 This document is applicable to onshore pipeline systems used in transportation in the petroleum and natural gas industries, connecting wells, production plants, process plants, refineries and storage facilities, including any section of a pipeline constructed within the boundaries of such facilities for connection purposes. The extent of pipeline systems covered by this document is illustrated in Figure 1. This document does not deal specifically with the integrity of non-pipe elements. The pipeline segment between the wellsite and the gathering station, treatment plant or process plant (between Facilities 1 and 2 in Figure 1) is included in this document, though many mandatory elements of this document are not practical due to characteristics such as diameter, operating parameters, etc.\n1.3 This document applies to rigid, steel pipelines. It is not applicable for flexible pipelines or those constructed from other materials, such as glass-reinforced plastics.\n1.4 This document does not cover all conditions nor engineers' competency which might be related to pipeline integrity. The user can evaluate whether additional requirements are necessary.\n1.5 This document is used for integrity management, which is initiated at the design and construction stage of the pipeline. Where requirements of a design and construction standard (e.g. ISO 13623) are different, the provisions of this document will enhance the design and construction from an integrity perspective.\nGeneral information Status :Published Publication date :2019-05 Edition :1 Number of pages :108 Technical Committee:Pipeline transportation systems Buy this standard\nFormat Language Paper CHF198 Life cycle\nA standard is reviewed every 5 years\nRevisions / Corrigenda Now ISO 19345-1:2019", "pred_label": "__label__POS", "pred_score_pos": 0.5073738098144531}
{"content": "Think about this. You can pick up a beautiful piece of art, set it on a table in front of you, and gaze at it. You will have “set it before” yourself. This Scripture tells us that you can set the Lord always before yourself too. Does this mean that you adjust His position, moving Him to a space right in front of you?\nObviously, this is a silly question. God does not move from His magnificent position. It’s we that move ourselves. If we were going to the left or to the right, we re-center ourselves on Him. If our gaze has been wandering, we check ourselves. We stop allowing it to wander. We adjust where we are pointing our attention, and we fix it on Him. As the NIV renders this verse,\n“I keep my eyes always on the Lord…”\nLearning to check ourselves and re-center on Him is a lifelong journey of growth. The more we practice, the more we will find this to be true:\n“…because He is at my right hand I shall not be moved”. The right hand is an essential Scriptural symbol, occurring 167 times in the Bible (KJV). It embodies the concept of strength. When we gradually learn more and more to fix our attention on Jesus throughout the day, our strength grows. By very gradual increments, we become immovable. Slowly but surely, He makes us unshakable.\nHere are three more benefits that come from this way of living, found in the same Psalm:\n1. Perpetual guidance.\n“I will praise the Lord, who counsels me… You make known to me the path of life…” (v. 7, 11, NIV). When we set the Lord always before us, it helps us tune into His voice. We grow in sensitivity to His constant whispers, directing us along the path of life.\n2. Restfulness of soul and body.\n“…My body also will rest secure” (v. 9). When we fixate on Jesus, our heart learns how big He is. The immensity of His love and power invests our whole being with His rest and security.\n3. Fullness of joy.\n“You will fill me with joy in your presence, with eternal pleasures at your right hand” (v. 11). As we gaze on Him, we connect our spirits into all the vibrancy of His closeness. His own joy permeates us. His pleasures become our own.\nSo, dear one, let us fix our eyes on Jesus. Let’s re-center on Him throughout the day, over and over again, until it becomes second nature to us. Let’s learn to set Him always before us. We will not be shaken!\n********************************\nWhat are some ways that can help us remember to re-center on Jesus in the midst of busy days?", "pred_label": "__label__POS", "pred_score_pos": 0.8579994440078735}
{"content": "Ideascale and Betterific announced at the end of January that they were teaming up to bring the latter’s strengths in crowdsourced open innovation to Ideascale’s industry-leading innovation management platform. So why are they better together, and what can innovation teams expect from the arrival of the Betterific team?\nA New Perspective\nBetterific’s work has focused on widening the perspective of organizations that can struggle to secure an unbiased external perspective. While internal innovation can be a powerful force, there are situations where you need an outsider’s view, especially when you’re reaching out to a specific market, or trying to break into a new one. While client feedback and customer surveys can be invaluable, often being able to tap into the creativity of your broader audience pays substantial dividends.\nTo do this, Betterific offers a platform where users join brainstorms where a challenge is posed to its 25,000 strong and growing crowd team. Each brainstorm offers prizes for the best ideas, and the ideas can range from overhauling menus to coming up with new use cases for items. Each can be as broad or as specific as the organizer needs, and then ideas are collected and awarded.\nBetterific’s work in crowdsourced open innovation has been used for everything from product design to branding to solving some of the toughest political challenges with which ecological groups struggle. Now, it’ll be combined with IdeaScale’s powerful tools.\nA Stronger Team\nThe two together will extend IdeaScale’s innovation platform to both internal and external use cases. IdeaScale’s innovation management platform is designed for multiple scales of brainstorming and refining, from small teams to organization-wide votes on ideas.\nBetterific’s crowd and technology now extends that pipeline toward crowdsourcing and adds a useful next step for both open innovation and more focused approaches. For example, IdeaScale users aiming to develop a snack product can divide up tasks between what should be handled internally, such as product chemistry and manufacturing, and what needs more consumer feedback, such as names, specific flavors, and branding.\nIt also creates an effective feedback loop to assist in refining ideas and targeted markets. Developing new use cases for products, comparing crowd feedback on features to more specific feedback from vendors and users, and tweaking feature sets for different markets can all be further streamlined and incorporated into the cutting-edge data collection and analysis built into IdeaScale’s platform.\nThese tools can be used internally as well, building on IdeaScale’s success with open innovation. Organizations can adjust their approaches depending on their needs, such as starting by crowdsourcing internally from their team and gradually opening it up to the wider crowd as well.\nInnovation is increasingly the lifeblood of vital companies. As products improve in quality and consumers become more segmented in their needs and more discerning in their purchases, an innovation platform that can move from small teams through the entire pipeline to product launch and beyond will be the heart that keeps that lifeblood pumping. To learn more about Ideascale and Betterific’s ability to build creativity in your organization, contact us!", "pred_label": "__label__POS", "pred_score_pos": 0.7307016849517822}
{"content": "Enter PointsAutoplayAutocompleteHTML5FlashPlayerSpeedPrevious LectureComplete and continuePK205: Public Health NutritionCourse OverviewGetting started (1:00)Enrolment Form - Please Click SUBMIT under the formModule 1: Food basics and why food is a public health issueModule 1: Introduction (0:39)Lesson 1: Food and health (22:43)Lesson 2: A history of guidelines (24:00)Lesson 3: Current guidelines and controversies (21:06)Module 1: TestModule 2: Challenges for public healthModule 2: Introduction (0:41)Lesson 1: Pain points in medicine (11:40)Lesson 2: Successful interventions (14:09)Lesson 3: Unsuccessful interventions (12:14)Module 2: TestModule 3: Growth industries and conflicts of interestModule 3: Introduction (0:43)Lesson 1: Big industries - Food and Pharmaceuticals (8:16)Lesson 2: Big academia - the flaws in the system (16:17)Lesson 3: Cases for legislation - sugar and fat taxes (11:18)Module 3: TestModule 4: When is the evidence strong enough?Module 4: Introduction (0:54)Lesson 1: Cause and effect in nutritional epidemiology (28:46)Lesson 2: Risks and benefits in interventions (17:42)Lesson 3: What don't we know and why (13:14)Module 4: TestModule 5: Public health into practiceModule 5: Introduction (0:31)Lesson 1: Salt and micronutrients (15:40)Lesson 2: Fibre (18:34)Lesson 3: A GPs perspective on public health (15:52)Module 5: TestSummary and where to now?Summary and key take aways (0:40)How did we go?Module 5: IntroductionLecture content lockedIf you're already enrolled,you'll need to login.Enroll in Course to Unlock", "pred_label": "__label__POS", "pred_score_pos": 0.5425082445144653}
{"content": "Abstract\nDuring adolescence, the brain continues to undergo vital developmental processes. In turn, complex behavioral and cognitive skills emerge. Unfortunately, neurobiological development during adolescence can be influenced by environmental factors such as drug exposure. Engaging in drug use during adolescence has been a long-standing health concern, especially how it predicts or relates to drug using behavior later in life. However, recent findings suggest that other behavioral domains, such as learning and memory, are also vulnerable to adolescent drug use. Moreover, it is becoming increasingly apparent that deficits in learning and memory following adolescent drug use endure into adulthood, well after drug exposure has subsided. Although persistent effects suggest an interaction between drug exposure and ongoing development during adolescence, the exact acute and long-term consequences of adolescent drug exposure on substrates of learning and memory are not fully understood. Thus, this review will summarize human and animal findings on the enduring cognitive deficits due to adolescent drug exposure. Moreover, due to the fact that adolescents are more likely to consume drugs of abuse legally available to adults, this review will focus on alcohol, nicotine, and marijuana. Further, given the critical role of the frontal cortex and hippocampus in various learning and memory domains, the impact adolescent use of the previous listed drugs on the neurobiology within these regions will also be discussed.\nAll Science Journal Classification (ASJC) codes Neuropsychology and Physiological Psychology Cognitive Neuroscience Cellular and Molecular Neuroscience", "pred_label": "__label__POS", "pred_score_pos": 0.6393675208091736}
{"content": "hide\nFree keywords: -\nAbstract: Neuroticism is one of the “Big Five” personality factors and is characterized by a tendency to experience negative affect. We aimed to investigate how neuroticism influences the neural correlates for processing of emotional facial expressions. 68 healthy participants were presented with emotional dynamic facial stimuli, i.e. happy, neutral or angry, during functional MRI. Brain activations for the contrasts emotional vs. neutral, happy vs. neutral and angry vs. neutral were correlated with individuals’ neuroticism scores as obtained by the NEO Five Factor Inventory questionnaire and additionally investigated for gender differences. The bilateral medial temporal gyrus (MTG) was identified as key region in the processing of emotional faces and activations within this region correlated with individual neuroticism scores. Although female participants showed significantly stronger activation differences between emotional and neutral facial expressions in the left MTG, the correlation between activation and neuroticism scores did not show any significant gender differences. Our results offer for the first time a biological correlate within the face processing network for enhanced reactivity of neurotic individuals to emotional facial expressions which occurs similarly for both male and female participants.", "pred_label": "__label__POS", "pred_score_pos": 0.9534966945648193}
{"content": "According to a recent report published by Allied Market Research, titled, “\nCognitive Computing Market by Technology, Deployment Type, Enterprise Size, and Industry Vertical: Opportunity Analysis and Industry Forecast, 2019–2026,” the cognitive computing market size was valued at $8.87 billion in 2018, and is projected to reach $87.39 billion by 2026, growing at a CAGR of 31.6% from 2019 to 2026.\nCognitive computing refers to the development of computer systems model that simulates the human thought process as a human brain. These systems use natural language processing capability to tackle complex situations and learn from experience. Theyare capable of interacting with humans in a natural/human way, and help in making decisions based on the learning. Cognitive computing includes self-learning systems that use pattern recognition, data mining, and natural language processing to impersonate the way human brain works or takes decision. Moreover, cognitive computing is a sub-technology of artificial intelligence (AI) that includes almost the same underlying technologies to power its applications such as neural networks, expert systems, robotics, and virtual reality.\nIncreased adoption of cognitive computing applications in large and small & medium enterprises boosts the growth of the market. In the prevailing business scenario, demand for unstructured data insights is witnessing a steady growth amongst the organizations. Increase in amount of unstructured data availability is one of the major growth factors for the cognitive computing market in various regions. Moreover, increase in trend of cloud-based services and big data analytics adds to the growth of cognitive computing. On the other hand, huge cost involved in the deployment of cognitive computing is anticipated to hinder the growth of the market.\nThe global cognitive computing market growth is in its evolving phase in most of the geographical regions. Natural language processing has driven larger portion of the market in present scenario owing to its dynamic features. It can respond in natural language, in turn inspiring its major use in the field of healthcare, banking, and financial sector.\nKey Findings Of The Study By technology, the natural language processing segment dominated the cognitive computing market forecast. However, the machine learning segment is expected to exhibit significant growth during the forecast period in the cognitive computing industry. By deployment type, the on-premise segment dominated the cognitive computing market share in 2018. However, the cloud segment is expected to exhibit significant growth during the forecast period. By enterprise size, the small and medium enterprises segment dominated the market revenue in 2018. However, thelarge enterprises segment is expected to exhibit significant growth during the forecast period Depending on industry vertical, the healthcare industry generated the highest revenue in 2018 owing toits high R&D expenditure capability for enabling technologies. However, the BFSI sector is expected to witness a considerable growth in the near future. Region wise, North America dominated the cognitive computing market trends in 2018. Whereas, Asia-Pacific is expected to witness significant growth in terms of CAGR in the coming years.\nSome of the key market players profiled in the cognitive computing market analysis include 3M, Google LLC, Hewlett Packard Enterprise Development LP, International Business Machines Corporation, Microsoft Corporation, Nuance Communications Inc., Oracle Corporation, SAP SE, SAS Institute Inc., and Tibco Software Inc. Major players operating in this market have witnessed significant adoption of strategies that include business expansion and partnership to reduce supply and demand gap. With increase in artificial intelligence R&D initiatives across the globe, major players have integrated their product portfolio to provide differentiated and innovative products. This study includes marketanalysis, trends, and future estimations to determine the imminent investment pockets.", "pred_label": "__label__POS", "pred_score_pos": 0.8102142214775085}
{"content": "We engage clients in a three-part process that integrates Western business models with Eastern wisdom practices. Our Bhavana-Effect includes 12 PRACTICES that cultivate being to the potential future, awaken an expanded mindset with practices, and integrate continual learning and inquiry. sustain AWAKEN.\nAn inquiry into the nature of being that engages your body, mind, and language. Through an ontological inquiry (into the nature of what it is to\nbe human) we increase self-awareness and cultivate insight that expands potential. INTEGRATE.\nA transition that evolves our mindset beyond past frames of reference. Through an integral approach, we identify and support new structures and practices. We become aware of outmoded perceptions which encourages a process of unlearning.\nSUSTAIN.\nEngaging in a life of contemplative practice supports continual learning and unlearning, increased levels of awareness and intentional action. A sustained practice grounds one in a commitment to maintaining growth.\nAre you ready to support the core of your being?\nAt Bhavana Learning Group, our ontological learning model focuses first on\nbeing (A) as foundational to shaping doing (B) and knowing (C). Our philosophical grounding involves differentiating being of being human: Ground: WHO we are as a context for commitment — the GROUND of being; then, Fruition: WHY we engage as a context for possibility — the FRUITION of being. Then Path: HOW/WHAT we engage as the process/content — the PATHWAY.\nWe employ this three-fold inquiry — Ground/Fruition then Path — as distinct from traditional process-content learning models. The result cultivates an\nthat includes and cultivates elements of our being, such as our history, environment, culture, and potential that conventional learning models may separate, dismiss or compartmentalize. interdependent awareness\nWith our 12 PRACTICES we become present to our entire being, learning occurs more fully — through body, perceptions, and language. Through increasing awareness, we access who we are as an observer; Through enhancing listening, we access a new relationship to language. Through mindfully breathing, we access our learning from our body.", "pred_label": "__label__POS", "pred_score_pos": 0.9887209534645081}
{"content": "A core outcome set in subarachnoid research is both necessary and attainable. Our systematic review demonstrated substantial heterogeneity in the outcome measures employed in subarachnoid haemorrhage research. The development of a specific core outcome set will engage relevant stakeholders including patients, families, researchers, clinicians, allied health workers and policy-makers and identify which outcome measures should be prioritized during research. This specific core outcome set will aim to achieve consensus on how and when to measure these outcomes.\nShane W English (Clinician, Researcher, Project Lead - Canada)\nChristopher R Andersen (Clinician, Researcher, Project Lead - Australia/UK) Maria Luisa Marti (Patient Research Partner) Philip Talbot (Patient Research Partner) Victoria Saigle (Coordinator, Researcher) Justin Presseau (Social Scientist, Researcher) Anthony Delaney (Clinician, Researcher) Simon Finfer (Clinician, Researcher)\n- COS for clinical trials or clinical research\n- Consensus meeting\n- Delphi process - Focus group(s) - Literature review - Other - Systematic review\nInitial scoping review (published) followed by Q-sort method for stakeholder attitudes, Delphi process +/- Consensus meeting for final COS.", "pred_label": "__label__POS", "pred_score_pos": 0.9997013211250305}
{"content": "Standard & Poor’s Ratings Services announced that it has revised the outlooks to stable from negative on its long-term counterparty credit and financial strength ratings on NIPPONKOA Insurance Co. Ltd. (A+/Stable/–) and Aioi Insurance Co. Ltd. (A-/Stable/–), “reflecting the companies’ improving profitability and capitalization.”\nS&P also affirmed the above ratings on the companies. The bulletin noted that “despite projected pressure on premium income due to a drop in the unit price of core auto insurance products, the company’s profitability and capitalization are improving. Fewer natural disasters in Japan have lowered the companies’ losses, while the insurers have enhanced their underwriting capabilities.”\n“Previously, concerns over potential deterioration in NIPPONKOA and Aioi’s investment performance and capitalization, caused by stock price fluctuation in Japan, have been a major negative constraint on the ratings on the companies,” stated S&P Credit analyst Kai Nakajima. “But, concerns have been alleviated by the companies’ disposals of stockholdings held for business relationship purposes and the recovery in Japanese stock prices.”\nThe report indicated that “NIPPONKOA’s net premium income is likely to have fallen at the end of March 2004 from the previous year. However, the company should be able to mitigate the impact on its profitability through over-the-counter sales at banks and sales of non-life insurance products through its alliance with Taiyo Life Insurance Co. (A/Stable/–). The sales of its products through an alliance with Meiji Yasuda Life Insurance Co. (BBB+/Negative/A-2), commenced in January 2004, will also help alleviate the pressures.”\nS&P also said that “Aioi’s net premium income generated from Toyota-related sales has increased steadily, supported by its close ties with Toyota Motor Corp. (AAA/Stable/A-1+) in both operations and finance, which is expected to mitigate downward pressures on premium income.\n“In fiscal 2001 (ended March 31, 2002), Aioi suffered a substantial deterioration in profitability and capitalization due to losses incurred from reinsurance transactions relating to the terrorist attacks in the U.S. However, its efforts to enhance underwriting capabilities and reduce operating expenses, in addition to external factors, such as fewer natural disasters, have helped improve its combined ratio.”\nWas this article valuable?\nHere are more articles you may enjoy.", "pred_label": "__label__POS", "pred_score_pos": 0.7075269222259521}
{"content": "Difference Between Commercial vs Residential Vertical Platform Lift\nWheelchair lifts are a great help for people with mobility issues. Going up and down the stairs is tricky and risky for them, and this elevation device can assist them in moving from one floor to another. You may have already seen them in nursing homes, but they also aid seniors and those with disabilities in public spaces.\nAt a glance, residential and commercial\nwheelchair lifts in Louisiana look the same. But, the latter has special features that make them fit for hospitals, schools, restaurants, and public buildings. It's because they need to conform to the guidelines and safety standards set by the Americans with Disabilities Act (ADA), allowing those with mobility issues to use them with ease. ADA Requirements for Commercial Lifts\nThe ADA act was signed into law in 1990 to give every person with a disability the chance to actively participate in society and empower them to live independently. To do so, they must have ready access to all public and commercial spaces. With multistory buildings, they should have a wheelchair lift if ramps or elevators are impractical.\nThese lifts are further subject to standards to ensure they're durable and fit for public use. They must have specific features, including:\nLifting capacity 8 times their rated capacity. Lighted power buttons to add visibility to the control panel. Power-operated doors and gates that open for at least 20 seconds. Mechanisms that make them independently operable, allowing unassisted entry and exit. A platform, unless the device is placed in spas or near the pool. You can install a stairlift chair in those areas, provided there's always someone to assist the person with mobility issues. Battery power that allows the mobility product to operate under full load for a minimum of 5 cycles.\nBesides these requirements, commercial lifts are typically enclosed. They offer more privacy and security for people with visible disabilities.\nThe ASME A18.1 Standard for Residential Lifts\nMeanwhile, residential platform lifts also follow code requirements. It's to ensure they're strong, durable, and functional even if they're less frequently used than commercial ones. They should be easy to operate as well, even without any assistance.\nResidential platform lifts must meet the American Society of Mechanical Engineers (ASME) A18.1 Standard before they're sold. This code covers the design, construction, testing, inspection, installation, and operation of the mobility product. It also touches on maintenance and repair guidelines.\nThe ASME A18.1 Standard specifies that residential lifts must:\nMaintain limited operating speed Have a smaller platform area to fit residential units, and; Operate under the continuous control of the user or attendant\nMeanwhile, they shouldn't be:\nFully enclosed, or; Designed to go up more than one floor\nIn addition, stair chair lifts are classified as residential units and are safe for home use. Still, have someone supervise the user when they get on and off the elevation device.\nFinal Thoughts\nIt’s hard to differentiate a residential from a commercial\nvertical platform lift in Louisiana while browsing the internet or looking at them in a store. So, find a shop that can answer your questions and offer a free consultation to help you choose a machine tailored to your needs. Get in touch with Stairlifts of Louisiana today; their trained experts will be happy to assist you. They have a wide range of ADA and ASME-compliant products at the best prices.", "pred_label": "__label__POS", "pred_score_pos": 0.8628087639808655}
{"content": "Synopses & Reviews Synopsis A conceptual update of affordance theory that introduces the mechanisms and conditions framework, providing a vocabulary and critical perspective.\nTechnological affordances mediate between the features of a technology and the outcomes of engagement with that technology. The concept of affordances, which migrated from psychology to design with Donald Norman's influential 1988 book, The Design of Everyday Things, offers a useful analytical tool in technology studies--but, Jenny Davis argues in How Artifacts Afford, it is in need of a conceptual update. Davis provides just such an update, introducing the mechanisms and conditions framework, which offers both a vocabulary and necessary critical perspective for affordance analyses.", "pred_label": "__label__POS", "pred_score_pos": 0.8248503804206848}
{"content": "This paper presents discussions on observed scenarios that characterize water-based recreational activities with an aim of laying grounds for appreciating relationships that enhance or hamper ecotourism development in Lake Victoria, Kisumu County. The study was premised from an argument that lake water resources demonstrate prospects for activities like swimming, boating, sunbathing, skiing, recreational fishing and visual amenities among others. The study was conducted through observations and confirmatory follow up queries from relevant stakeholders along Lake Victoria from Asat, Ogal, Usoma and Lwangni beaches of Lake Victoria. The main objective was to examine existing trends of water-based activities in relation to ecotourism and envisage potentials of each beach water front for recreation in Kisumu County. Thus, this paper presents results of a systematic synthesis of interactions between lake (surface) water and outdoor recreation, a significant socioeconomic subsystem. The study maps out characteristics of accessible water front areas, popularly known as beaches, for their ecological sensitivity and ascertains the possibility of the sites to be planned or augmented to facilitate ecotourism development. Findings reveal the spatial potential of the sites but with gaps that intimidate possible popularity of ecotourism industry due to intentional human activities, negligence and perceptions. The existing technical and scientific knowledge on Lake Victoria Basin has been boosted by this study; hence, results and recommendations potentially enable academic institutions, development agencies and Kisumu County Government to seriously begin ecotourism development, which has remained behind most developed nations", "pred_label": "__label__POS", "pred_score_pos": 0.692166805267334}
{"content": "The enemy within – How can you prevent employee fraud?\n$225.00\nDescription\nAbstract: Occupational, or employee, fraud is an ongoing hazard to businesses’ bottom lines. It can take several forms, from skimming, to billing schemes, to corruption, to asset misappropriation. This article discusses ways business owners and management can prevent employee fraud and reduce its impact, such as separating duties and using physical controls. The article suggests that taking some of these commonsense steps can reduce the potential for employee fraud.", "pred_label": "__label__POS", "pred_score_pos": 0.9299283027648926}
{"content": "Purpose\nTo understand how the Take Home Naloxone (THN) program is implemented in two pilot correctional facilities in British Columbia (BC), Canada, in order to identify areas for program improvement and inform the expansion of the program to other Canadian correctional facilities The paper aims to discuss these issues.\nDesign/methodology/approach\nTwo focus groups and one interview were conducted with healthcare staff at two pilot correctional facilities. Sessions were audio recorded, transcribed verbatim and divergent and convergent experiences within and between the facilities were explored in an iterative process. Key themes and lessons learned were identified and later validated by focus group participants.\nFindings\nKey themes that emerged included: challenges and importance of the train-the-trainer program for healthcare staff conducting participant training sessions; potential for improved prison population engagement and awareness of the program; tailoring program resources to the unique needs of an incarcerated population; challenges connecting participants to community harm reduction resources following release; and clarifying and enhancing the role of correctional officers to support the program.\nResearch limitations/implications\nThe correctional setting presents unique challenges and opportunities for the THN program that must be considered for program effectiveness.\nOriginality/value\nThis evaluation was conducted to inform program expansion amidst a historic opioid overdose epidemic in BC, and adds to the limited yet growing body of literature on the implementation and evaluation of this program in correctional settings globally.", "pred_label": "__label__POS", "pred_score_pos": 0.8959661722183228}
{"content": "Abstract\nQRS Frequency and CRT Introduction QRS characteristics are the cornerstone of patient selection in cardiac resynchronization therapy (CRT) and the presence of left bundle branch block (LBBB) and baseline QRS ≥150 milliseconds portends a good outcome. We previously showed that baseline QRS frequency analysis adds predictive value to LBBB alone and have hypothesized that a change in frequency characteristics following CRT may produce additional predictive value. Methods We examined the QRS frequency characteristics of 182 LBBB patients before and soon after CRT. Patients were assigned to responder and nonresponder groups. Responders were defined by a decrease in left ventricular end-systolic volume (LVESV) ≥15% following CRT. We analyzed the QRS in ECG leads I, AVF, and V3 before and soon after CRT using the discrete Fourier transform algorithm. The percentage of total QRS power within discrete frequency intervals before and after CRT was calculated. The reduction in lead V3 power <10 Hz was the best indicator of response. Results Baseline QRS width was similar between the responders and nonresponders (162.2 ± 17.2 milliseconds vs. 158 ± 22.1 milliseconds, respectively; P = 0.180). Responders exhibited a greater reduction in QRS power <10 Hz (-17.0 ± 11.9% vs. -6.6 ± 12.5%; P < 0.001) and a significant AUC (0.743; P < 0.001). A ≥8% decline in QRS power <10 Hz produced the best predictive values (PPV = 84%, NPV = 59%). Importantly, when patients with baseline QRS <150 milliseconds were compared, the AUC improved (0.892, P < 0.001). Conclusions Successful CRT produces a significant reduction in QRS power below 10 Hz, particularly when baseline QRS <150 milliseconds. These results indicate that QRS frequency changes after CRT provide additional predictive value to QRS alone.\nKeywords biventricular pacing cardiac resynchronization therapy frequency analysis heart failure left bundle branch block ASJC Scopus subject areas Cardiology and Cardiovascular Medicine Physiology (medical)", "pred_label": "__label__POS", "pred_score_pos": 0.5884009599685669}
{"content": "Author(s): Kneidinger-Müller, Bernadette Abstract:\nDigital traces occur as a consequence of using digital devices or applications, but they can also be produced intentionally, as in the case of self-tracking activities. Self-tracking increases the amount of data that represents users’ or communities’ identity traces, and individuals, institutions, and companies are interested in analyzing these data, but few consider the framing conditions of the data collection, distribution, and evaluation. This article demonstrates how contextual factors influence self-observation data. Based on approaches of a sociology of quantification and a theoretical discussion of metadata in scientific research, it examines the individual, social, and technological contextual factors that influence the production, analysis, distribution, and interpretation of digital self-tracking data. The article develops systematization of the phenomenon of selftracking data.", "pred_label": "__label__POS", "pred_score_pos": 0.5971558094024658}
{"content": "The International Cohort Consortium of Infectious Disease (\nRESPOND\n) was formed in 2017 as a prospective, multi-cohort collaboration for the study of infectious diseases, with a special focus on people living with HIV (PLWH).\nRESPOND was founded upon the groundwork laid by outstanding European HIV cohort collaborations such as EuroSIDA, the Collaboration of Observational HIV Epidemiological Research Europe (COHERE) and Data Collection on Adverse events of Anti-HIV Drugs (D:A:D) studies, and utilizes a similar, well-established infrastructure.\n17 cohorts are currently involved in the RESPOND consortium with over 30,000 individuals are under active follow up.\nRESPOND offers a research framework with a flexible organization, applying a common data model across different substudies, utilizing one shared data pool. Additionally, all involved in RESPOND can contribute to the ongoing scientific agendas. Together, these dynamic features facilitate responses to a broad range of unmet research needs.\nThe large size of RESPOND consortium and a heterogeneous study population with participants from across the whole of Europe and Australia and a high degree of data quality — including the central validation of\nstandardized clinical event definitions\n— ensure that the results are reliable and applicable to a broader population of PLWH.\nRESPOND aims to address clinically relevant research questions, including the risk and outcomes of non-AIDS comorbidities and the possible relationship to long-term ART exposure; to the outcomes and treatment of viral hepatitis B (HBV), hepatitis C (HCV), and tuberculosis (TB) co-infections; and to support public health initiatives.\nThe consortium is an open network that welcomes additional cohorts to join if\npredefined criteria regarding the inclusion\nof a minimum number of participants, the need for a designated data manager, and data quantity and quality are met.\nFor more information about RESPOND, please contact the Coordinating Centre at: respond.rigshospitalet@regionh.dk\nRESPOND structure:", "pred_label": "__label__POS", "pred_score_pos": 0.7653850317001343}
{"content": "Accuracy, precision, usability, and cost of portable silver test methods for ceramic filter factories\nLocally manufactured ceramic water filters are one effective household drinking water treatment technology. During manufacturing, silver nanoparticles or silver nitrate are applied to prevent microbiological growth within the filter and increase bacterial removal efficacy. Currently, there is no recommendation for manufacturers to test silver concentrations of application solutions or filtered water. We identified six commercially available silver test strips, kits, and meters, and evaluated them by: (1) measuring in quintuplicate six samples from 100 to 1,000 mg/L (application range) and six samples from 0.0 to 1.0 mg/L (effluent range) of silver nanoparticles and silver nitrate to determine accuracy and precision; (2) conducting volunteer testing to assess ease-of-use; and (3) comparing costs. We found no method accurately detected silver nanoparticles, and accuracy ranged from 4 to 91% measurement error for silver nitrate samples. Most methods were precise, but only one method could test both application and effluent concentration ranges of silver nitrate. Volunteers considered test strip methods easiest. The cost for 100 tests ranged from 36 to 1,600 USD. We found no currently available method accurately and precisely measured both silver types at reasonable cost and ease-of-use, thus these methods are not recommended to manufacturers. We recommend development of field-appropriate methods that accurately and precisely measure silver nanoparticle and silver nitrate concentrations.", "pred_label": "__label__POS", "pred_score_pos": 0.5127052664756775}
{"content": "In recent months, Frontier has observed an increasing trend among Australian institutional investors in launching (or at least discussing) strategic partnerships with their fund managers. The reasons for this are varied; but extracting intellectual property (I.P.), reducing fees and reducing the number of manager relationships; are three commonly quoted and perfectly valid reasons.", "pred_label": "__label__POS", "pred_score_pos": 0.9757131338119507}
{"content": "Real Estate Real Estate Investment Trusts - Reit\nHow do REITs generate their stated returns?\nMany factors contribute to a REIT’s income-producing characteristics, including: generating income through efficiently collecting rents from tenants; purchasing and selling real property; realizing income from owning mortgage debt and the interest income it produces; and adding value by developing real property and selling it for profit.", "pred_label": "__label__POS", "pred_score_pos": 0.9999633431434631}
{"content": "Our approach to comprehensive financial planning is process-oriented and goal-driven – we seek to establish where you are now, determine what you need to maintain your lifestyle and achieve your objectives, and then develop a plan designed to fund those goals. And we do that by following five clearly defined and thoroughly executed steps:\nPlease keep in mind that diversification and asset allocation do not ensure a profit or protect against a loss.\nInvesting involves risk and you may incur a profit or loss regardless of strategy selected.\nSomeone's Sitting in\nthe Shade Today Because Someone Planted a Tree a Long Time Ago.", "pred_label": "__label__POS", "pred_score_pos": 0.9471310377120972}
{"content": "Criminal Defense Lawyer in Denver Colorado\nAs a criminal defense lawyer in Denver, CO from The Law Firm of Richard J. Banta, P.C. understands, a criminal arrest is an anxiety-inducing experience. For those who have been arrested for a criminal offense, the idea of hiring an attorney they have no prior familiarity with can lead to panic. They may believe that to present a proper defense, there has to be a certain level of social or professional intimacy. Unfortunately, this unfounded belief might cause them to consider representing themselves instead of hiring a reliable criminal defense lawyer in Denver. Below, we tell you why this isn’t a good idea.\nThere are at least five reasons you should never represent yourself in a criminal trial, especially when the charge involves a felony:\n1. Consequences\nThe first reason to consider hiring a Denver, CO criminal defense lawyer, is the potential consequences you face from a weak defense. Some misdemeanors and most felony convictions result in significant jail or prison time. Therefore, it is paramount that you receive the best defense possible. While hiring a free lawyer may be appealing initially, it could cost you in the end if you lose the case.\n2. Emotions\nNext, an arrest alone is a traumatic experience. However, when you throw a jail cell and court dates into the equation and you consider that every day during the trial your character and innocence are in question, your emotions are likely in a fragile state. Courtrooms are places of extraordinary decorum, and any outburst, no matter how justified or understandable, can affect your case (potentially making your defense more challenging to present). Your criminal defense lawyer from CO can speak for you and advocate on your behalf in the courtroom.\n3. Relationships\nDo you have any professional relationships with prosecutors? Have you known them for years or possibly gone to school with them? While it might not seem like it, professional relationships matter. A defense attorney who knows the prosecution is likely better able to make deals and negotiate outside of the courtroom, possibly leading to lesser charges and plea deals.\n4. Strategy\nAlso, when a defense lawyer is familiar with the prosecutor in your case, they are often familiar with their offensive style and approach. This familiarity means that your potential attorney can better prepare your defense, punching holes in the prosecution’s case and forcing them to rethink their strategy.\n5. Knowledge\nLastly, and likely most important, an attorney has the legal knowledge and prowess to fight your case. Did you attend years of law school? Did you pass the bar? Are you a seasoned law professional with years of courtroom litigation experience? If not, then the thought of putting on your own defense is dangerous.\nDon’t put years of your life on the line because you think your attorney doesn’t know you well enough to fight for you. We have trained tirelessly to ensure that you and every other defendant has a fair trial and a sound defense. Contact a criminal defense lawyer in Denver, Colorado from The Law Firm of Richard J. Banta, P.C. today for prompt assistance.", "pred_label": "__label__POS", "pred_score_pos": 0.506580114364624}
{"content": "Current progress with serological assays for exotic emerging / re-emerging viruses\nMather, Stuart and Scott, Simon and Temperton, Nigel and Wright, Edward and King, Barnabas and Daly, Janet (2013)\nOfficial URL: http://www.futuremedicine.com/doi/abs/10.2217/fvl.13.60\nAbstract\nRecent decades have witnessed an unprecedented rise in the outbreak occurrence of infectious and primarily zoonotic viruses. Contributing factors to this phenomenon include heightened global connectivity via air travel and international trade links, as well as man-made environmental alterations, such as deforestation and climate change, which all serve to bring humans into closer contact with animal reservoirs and alter the habitat of vectors, thus facilitating the transmission of viruses between species. Serological assays are integral to tracking the epidemiological spread of a virus and evaluating mass vaccination programs by quantifying neutralizing antibody responses raised against antigenic epitopes on the viral surface. However, conventional serological tests are somewhat marred by equipment and reagent costs, the necessity for high-containment laboratories for studying many emerging viruses, and interlaboratory variability, among other issues. This review details ‘next-generation’ assays aimed at addressing some of the persistent problems with viral serology, focusing on how manipulating the genomes of RNA viruses can produce attenuated or chimeric viruses that can be exploited as surrogate viruses in neutralization assays. Despite the undoubted promise of such novel serological platforms, it must be remembered that these assays have to withstand rigorous validation and standardization measures before they can play an integral role in curtailing the severity of future emerging virus outbreaks.\nActions (Archive Staff Only)", "pred_label": "__label__POS", "pred_score_pos": 0.580776572227478}
{"content": "In a recent poll conducted by Pace University, a group of 850 Americans of varying age were asked about cyberterrorism. The question specifically was \"do you believe a technology-based terrorist threat is likely to occur within the next 3-5 years?\" This poll is the latest in a series of media (e.g. Gallup) and academic probings that seek to understand the public view of cyber national security.\nThe results of the Pace poll were interesting to say the least. There was a clear division between age groups of just how great a threat cyberterrorism is. For participants under 30, roughly 58 percent believed in an imminent cyberterrorist threat, whereas participants over the age of 65 polled much higher at 85 percent. The ultimate takeaway from this particular poll is that a sizeable majority of Americans recognize the reality of cyberterrorism.\nWhat are the implications here? Firstly, it proves that the concept of cyberwar has fully imprinted itself on the American consciousness. It took a long time to get to this point, but with forced transparency via whistleblowers, American citizens are finally comprehending the downside to an interconnected cyberworld. The more that devices of all kinds link up with each other, the more likely they are to all be affected in a major hack. Additionally, revelations about government incompetence with regards to cybersecurity, especially in areas vital to national security, have left U.S. citizens slightly paranoid about their safety.\nTo qualify as cyberterrorism, threat actors must seek to harm innocent lives via attacks on infrastructure or personal safety. Nation-states, such as in the Stuxnet nuclear facility attack or the U.K. railway system hacks, have clearly engaged in what I consider to be cyberterrorism. Additionally, as I've reported, malicious hackers have gone after petrochemical plants, engineering companies, government data centers, and many others.\nWith awareness growing of the true threat that cyberterrorism brings, the next steps are crucial. As more individuals become educated about cyber threats to their safety, it is vital that the populous demands more from its leaders. At all levels of the American government, prominent individuals and entire departments have dropped the ball on cybersecurity.\nAs I said in a previous article, \"if the U.S. political sphere does not adapt and continues on its road of not employing a significant amount of outside help, I can confidently say we are not prepared to face a nation-state hack or other serious threat.\" These words are never more true than they are right at this moment. As Americans, no matter the political affiliation, we must demand more from our leaders. We must demand prominent focus on cybersecurity comprehension and efficiency rather than giving simple lip service to it.\nOur future depends on it.\nPhoto credit: Mike Herbst", "pred_label": "__label__POS", "pred_score_pos": 0.6566876173019409}
{"content": "The article evaluates the influence of a wide range of socio-demographic, job and company-related characteristics on the likelihood of low earnings by applying logistic regression on a broad range of Labour Force Survey data. We evidenced that the average impact of the company-related characteristics is three times stronger than the impact of personal characteristics. We also found that working full-time considerably decreases this risk of low wages, but company-related and personal characteristics (except for the kind of company’s economic activity) have not provided a rent (benefit) from working full-time. The underlying conclusion is that reforms decreasing the size of the low-wage sector in the former transition countries should be focused on targeted employment programmes enhancing transitions to more profitable economic activities instead of possibly maintaining the unprofitable industries at all costs. Additionally, the reforms should be concentrated on introducing employment regulations to harmonise the rules of employment among all contract types, which would put the part-timers and the underemployed on a more equal footing with fulltime workers especially in terms of pension schemes and access to training.", "pred_label": "__label__POS", "pred_score_pos": 0.6623671054840088}
{"content": "概要 This study examined the relation between children's spontaneous proto-communicative acts and their mothers behaviors. 30 mothers and their 17-20 months participated in this study. A variety of materna...l behaviors were observed in mother-child play interactions at home, and categorized from the view point of mother's gaze directions, and contingent/responsive behaviors and initiative behaviors to their children. Children's proto-communicative acts were observed in three kinds of toy presentation situations, and classified into proto-declarative acts, proto-imperative acts, and information-seeking acts. The correlation coefficients of these three variables with maternal gaze directions and behaviors were calculated. As a result, children's proto-declarative acts were significantly correlated with maternal gaze direction to their children's faces and behaviors. And then, correlations of children's proto-declarative acts with maternal contingent/responsive and initiative behaviors were significant (r=.44, p< .05 ; r=-.36, p<.05). In addition, the correlation coefficients of children's proto-declarative pointing, showing. utterance, and looking with maternal behaviors, gaze directions were calculated. Mother's contingent/responsive behaviors and gazes to the same objects as their children's gaze were significantly correlated to children's proto-declarative utterances and lookings. These results suggest that maternal attentive lookings and contingent responses to children's behaviors facilitate children's proto-declarative acts, especially proto-declarative utterances and lookings.続きを見る", "pred_label": "__label__POS", "pred_score_pos": 0.9939603805541992}
{"content": "Mediation\nWe typically advise clients to obtain legal advice prior to entering into the mediation process. If the process is successful and terms of agreement are agreed in principle, then each party must engage a solicitor to draw up and conclude the Separation Agreement.\nMediation is confidential and can be very cost effective.\nCollaborative Law\nConfidential negotiations take place in a series of meetings with both the husband and wife and their respective solicitors present. The parties work together to arrive at a resolution on all family law issues.\nThis approach allows the parties control of the final outcome, in lieu of a decision imposed by the Court. The Collaborative Family Law model focuses on the parties’ interests and aims to allow everyone to maintain their dignity, lessen hostility, and reduce negative impact on children. Kerry Clear is a qualified collaborative law practitioner and can advise and assist clients with this process.\nFeel free to contact us in confidence at any stage to discuss your legal requirements\nand one of our experienced and friendly team will assist you.", "pred_label": "__label__POS", "pred_score_pos": 0.745536208152771}
{"content": "COVID-19 has had a sudden and dramatic impact on our society – including our collective mental health. To better understand how employers should think about these changes, we surveyed 1,200 full-time U.S. workers around the effects of the pandemic. Here are four key takeaways that all companies need to consider as they plan for the long-range impacts of COVID-19.", "pred_label": "__label__POS", "pred_score_pos": 0.9819372296333313}
{"content": "Highlights of OIG activity from July 1, 2019 through September 30, 2019, are summarized below:\nAn OIG investigation established that a Chicago Police Department (CPD) lieutenant, and a sergeant and detective under the lieutenant’s command, mishandled CPD’s investigation of the off-duty death of a CPD member. The lieutenant, sergeant, and detective violated CPD rules by conducting an incompetent and incomplete investigation; furthermore, the lieutenant and the detective violated CPD rules, Cook County ordinances, and Illinois law when they were personally involved in removing the deceased CPD member’s body from the place of death without notification to or authorization from the Cook County Medical Examiner. OIG recommended that CPD impose discipline on the detective and sergeant commensurate with the gravity of the violations and issue a formal determination on the violations in the (since retired) lieutenant’s personnel file. CPD issued five-day suspensions for the detective and sergeant and agreed to place a copy of OIG’s report in the lieutenant’s personnel file. An OIG investigation established that an alderman’s staff assistant, in response to a ticket the alderman’s ward vehicle received for an expired vehicle registration, drafted a letter on official letterhead falsely claiming that the vehicle had been registered at the time the ticket was issued. That letter was subsequently submitted to the Department of Administrative Hearings, along with a forged Illinois vehicle registration card. OIG recommended that the alderman discharge the staff assistant and refer the staff assistant for placement on the ineligible for rehire list maintained by the Department of Human Resources. The alderman disagreed with OIG’s recommendation. An OIG investigation established that in 2015, a Chicago Department of Transportation (CDOT) asphalt laborer committed workers’ compensation fraud and collected $24,000 in unentitled payments. OIG’s investigation also revealed that the asphalt laborer had served nearly ten years of incarceration for federal weapons and narcotics convictions, which the asphalt laborer did not disclose to the City. OIG recommended that CDOT discharge the asphalt laborer and refer the asphalt laborer for placement on the ineligible for rehire list maintained by the Department of Human Resources. Following a settlement agreement, CDOT agreed not to seek termination of the asphalt laborer but, instead, agreed to suspend the asphalt laborer for 25 days. An OIG notification issued to the Department of Water Management (DWM) determined that the Department’s communication with customers affected by partial lead service line replacements did not align with best practices recommended by the American Water Works Association. The information provided to customers did not contain guidance regarding: the dangers of lead consumption; the dangers of lead consumption; the proper flushing technique; or the availability of point-of-use filters certified to reduce lead levels. A Public Safety Survey soliciting input from the community and members of CPD about areas of concern and priorities regarding public safety and police practices and operations, received over 1,000 responses. The results of the ongoing survey (found at research.net/r/XS87Z82) are summarized in the Third Quarter Report.", "pred_label": "__label__POS", "pred_score_pos": 0.6483370065689087}
{"content": "A Multi-Pronged Approach to a Global Pandemic\nThe COVID-19 pandemic has gripped America and the world in a medical, social, and economic crises, leading to severe economic slowdown globally and ushering in lockdowns across most U.S. states and >185 countries.\nMost experts suggest that the earliest an approved vaccine may become available is mid-2021, approximately 12-18 months after Sars-CoV-2 first emerged. So far seven coronaviruses already infect human beings and, like the common cold, we have yet to develop a vaccine for any of these. Without a vaccine or treatments in place, our health remains at risk as economies reopen.\n“A second wave of infections is inevitable.” -Anthony S. Fauci, director of the National Institute of Allergy and Infectious Diseases\nGlobally, approximately 2.2% of confirmed COVID-19 cases in the United States have died. By comparison, seasonal flu generally kills far fewer than 1% of those infected.² Over 59.6 million people are confirmed infected with COVID-19 worldwide.² Over 1.4 million deaths globally are attributed to COVID-19; over 259,800 in the U.S.² Over 60,800 citizens of New York City have been hospitalized with COVID-19.³\nAs economic hardship puts pressure on businesses to reopen, a prophylactic treatment is needed to ensure the safety of our communities.\nWe believe NED-260, an oral investigational product, has the prospect to provide two essential solutions:\nto protect against viral infection and cellular entry to halt disease progression in patients and prevent deaths\nWe at NED Biosystems believe NED-260 may offer vitally needed solutions to provide America and the world a way out of quarantine and isolation.\n²\nJohn Hopkins University, as of November 24, 2020 ³ New York State Department of Health, as of November 24, 2020", "pred_label": "__label__POS", "pred_score_pos": 0.8589791655540466}
{"content": "Motivations\nAn on-ramp venue to access and exit Oikos.exchange is critical to the success of the platform. Users must be able to convert TRX and other cryptocurrencies to Synths (sUSD primarily) to start their trading activities. Oikos Swap fulfills this role and provides such a service, allowing anyone to swap between TRX and TRC-20 pairs, including our synths (sUSD, sTRX, sBTC, sETH, etc.).\nPrice stability\nOikos swap requires balanced liquidity between both sides of the swap pools, in order to maintain a stable price. Low liquidity results in slippage between the quoted price and the actual price paid for the swap, even for small purchases. As such, providing liquidity is encouraged by sharing the 0.3% exchange fees entirely with liquidity providers. Users willing to take on this role must deposit a desired amount of TRX and their counter-value in the chosen token.\nE.g:\n10,000 * $0.017 / $0.025 = 6800 OKS Additional incentives\nProviding liquidity is not entirely risk-free and an additional incentive is assigned to users participating in this role. A portion of the weekly inflationary supply is rewarded automatically to liquidity pool (LP) providers. Deep liquidity will increase confidence in the on-ramp and off-ramp to Oikos Exchange and reduce trader losses due to slippage (when exchanging from synths to TRX). We will allocate around 7% of the weekly minted supply (around 109,000 OKS) for this purpose, which will be distributed proportionally across liquidity providers (starting with the sTRX/TRX pool).\nThe specific distribution rules will be as follows:\nOKS tokens will be distributed proportionally to each wallet based on the percentage of liquidity tokens in the pool at the end of each fee period. Once you have staked your LP tokens you will begin to accrue balance, as soon as the OKS rewards are deposited to the contract at the end of the transition period. Network effect\nUsing seigniorage is a practice used by multiple DeFi projects (Balancer, Curve, Thorchain, Bancor, Kava, Compound) which allows a startup to use the future earnings of the network, substantiated by the actual economic value of its token, to actively fuel network utility. Those who don’t participate in a meaningful way see their shares diluted. In conclusion, as a result of this strategy, users have an incentive to participate in network activities.\nConclusions\nToken-based network bootstrapping is effective because it increases user engagement levels and rewards participants with an asset directly tied to the network value. From this perspective, it can be seen as a pseudo equity. Some participants may sell these rewards. However, those that hold are essentially converted into “network shareholders”. These holders are more aligned with the long term prospects of the project and have the potential to contribute meaningfully to it, by adding value for both users and investors.", "pred_label": "__label__POS", "pred_score_pos": 0.7210851311683655}
{"content": "Abstract\nThis article examines the role of migrant workers in meat-processing factories in the UK. Drawing on materials from mixed methods research in a number of case study towns across Wales, we explore the structural and spatial processes that position migrant workers as outsiders. While state policy and immigration controls are often presented as a way of protecting migrant workers from work-based exploitation and ensuring jobs for British workers, our research highlights that the situation ‘on the ground’ is more complex. We argue that ‘self-exploitation’ among the migrant workforce is linked to the strategies of employers and the organisation of work, and that hyper-flexible work patterns have reinforced the spatial and social invisibilities of migrant workers in this sector. While this creates problems for migrant workers, we conclude that it is beneficial to supermarkets looking to supply consumers with the regular supply of cheap food to which they have become accustomed.", "pred_label": "__label__POS", "pred_score_pos": 0.8472174406051636}
{"content": "The Indian traditional PC market inclusive of desktops, notebooks, and workstations delivered a strong quarter with 9.2% year-over-year (YoY) growth in 3Q20 (July-September 2020), according to new data from the International Data Corporation (IDC) Worldwide Quarterly Personal Computing Device Tracker. 3.4 million units shipped during the quarter, as the demand for e-learning and remote working remained strong, resulting in 3Q20 being the biggest quarter in the last seven years in India. Although the commercial segment had very few government and education projects, the consumer segment recorded its biggest quarter ever with 2.0 million shipments, growing 41.7% YoY and 167.2% from the previous quarter.\nSchools and colleges continued to function virtually, leading to a surge in demand for consumer notebooks, especially in large cities. Despite the supply challenges, vendors were able to stock up for the upcoming online festivals. However, the demand for notebook PCs remains much higher than the current supply, which is likely to lead to another strong quarter of shipments in 4Q20 (Oct-Dec). New entrants like Xiaomi and Avita were able to leverage this opportunity but remained outside of the top five companies in the consumer segment. Apple shipments also grew 19.4% YoY as it ended its biggest quarter of shipments in the country.\nCommenting on current demand for consumer PCs, Bharath Shenoy , market analyst for PC Devices at IDC India states, “There is still a lot of uncertainty if and when will the schools and colleges return to physical classrooms at full strength. This is forcing students to manage all their learning virtually. This demand is expected to stay strong as India remains underpenetrated in PCs. To add to this, the growing broadband connectivity in the country is making online learning easier for students. Hence, this opportunity will continue to be relevant for PC vendors for at least a few more quarters.”\nIn the commercial segment, enterprises continued investing in PCs under their business continuity planning to manage their remote working requirements. However, the volume of key big deals has come down in this second wave of enterprise buying as compared to initial orders in 2Q20. This led to a marginal 3.1% YoY growth in the overall enterprise segment. Notebook shipments grew at a strong 70.1% YoY as enterprises preferred them over desktops. SMBs resumed their purchases after taking a slight pause, as business operations started for most of the sectors with a relaxation in the lockdown restrictions. Shipments to this segment grew 5.5% YoY in 3Q20. However, this growth can also be attributed to channel procurement for better control over inventories amid the uncertain supply situation in the ecosystem.\nTop 5 Company Highlights: 3Q20 HP Inc. retained the top position in the overall PC market with a share of 28.2% in 3Q20. The vendor recorded a strong quarter in both consumer and commercial segments with a 16.6% increase in shipments when compared to the same time a year ago. HP also remained the leader in the consumer segment. However, its market share fell to 24.2% in 3Q20 from 28.2% in 2Q20. Lenovo was marginally ahead of Dell with a share of 21.7% in its overall shipments. The vendor witnessed a 27% YoY growth in the consumer segment on the back of its portfolio extension this quarter. Also, the vendor registered 46.2% growth in its SMB shipments as it prepared the channel to avoid supply uncertainties in the coming months. Overall, Lenovo’s shipments fell 16.9% YoY in the absence of any large education deal this quarter. Dell Technologies secured third place with a share of 21.3% in the overall PC market as its shipments grew 18.2% YoY in 3Q20. After a few quarters of declining shipments in the consumer segment, the vendor returned to growth with an impressive 74.6% YoY increase in its shipments, replacing Lenovo in the second consumer ranking. Acer Group retained the fourth position with a 9.5% market share in 3Q20. However, the vendor registered a 12.4% decline in its overall shipments. Acer continued to dominate the commercial desktop category with a 27.1% share in 3Q20 as it managed to win a few key banking and education projects. ASUS maintained the fifth position and registered an impressive 55.4% YoY growth in its overall PC shipments. ASUS has been aggressive in expanding its offline presence, this helped the brand to secure the fourth position in the consumer segment. Also, this quarter the vendor officially entered the commercial segment with the launch of its Expert series.\n“Anticipating a longer work from home possibility, enterprises are getting ready for a larger mobile workforce and keep reducing their dependency on desktops. Also, SMBs started showing more momentum and will be critical in sustaining the ongoing growth in the commercial segment. Unfortunately, shortages of some key components continue to be a challenge. Vendors that will be able to manage the supplies of these components will benefit from this opportunity more as there is still a lot of untapped demand for PCs in the country,”\nsays Jaipal Singh, Associate Research Manager, Client Devices, IDC India.", "pred_label": "__label__POS", "pred_score_pos": 0.7339599132537842}
{"content": "Committed To Achieving Results For Cyclists And Pedestrians\nDrivers must be vigilant to avoid hitting pedestrians and cyclists. Too many drivers, however, do not heed the intense danger that vehicles pose to other people around them. When a pedestrian or cyclist is hit by a car or truck, they are likely to suffer significant injuries.\nAt Conway Denson & Associates, PLLC, our attorneys assist pedestrians, cyclists and parents of injured children after an auto accident. We have over 100 years of combined experience and a track record of successful case results in personal injury cases. You can depend on our team to protect your interests and seek compensation.\nPedestrian Accident Cases Are Rarely As Simple As They Seem\nCommon causes of pedestrian accidents include:\nDriving while talking on the phone or texting Drunk driving or fatigued driving Speeding or driving too fast under hazardous conditions Failing to stop at traffic lights or stop signs Failing to yield to pedestrians at crosswalks Failing to stop behind buses when appropriate Poor street lighting, broken traffic lights or other municipal problems\nPedestrian accidents are often severe for the person who is not protected by a vehicle. While drivers often walk away without a scratch, the pedestrian could suffer from life-changing damages, including traumatic brain injuries or spinal cord injuries. Some accidents cause fatal injuries.\nHowever, getting compensation is not always straightforward. Insurance companies do not prioritize your health or financial recovery, and they may deny you fair compensation. Our lawyers can help you gather evidence and communicate with the insurance companies to protect your claim.\nDepending on whether you live in Alabama or Mississippi, the laws that apply to your case may differ. Our team has experience with unique legal situations, liability and insurance issues in both states. We can explain your options and find solutions for you.\nTurn To Us For Reliable Advice\nConway Denson & Associates, PLLC, knows that the outcome of your case is a big deal. Compensation could make the difference between struggling to afford essential medical care and getting the full treatment you need to recover. Therefore, we are highly motivated to provide personalized, comprehensive service throughout settlement negotiations or trial.", "pred_label": "__label__POS", "pred_score_pos": 0.6719437837600708}
{"content": "The Golden Calf Rabbi Israel Chait\nA student’s transcription\nMoses ascended the mountain to have a rendezvous with God to learn first hand the teachings of the Torah and then to transmit them to the Jewish people. Instead Moses descended to a nation of idolaters rather than a people committed to accept a moral law based upon their intellectual conviction. The Torah explains the reason for this transformation. In Exodus 32:1, the Torah tells us that the people saw that Moses tarried from coming down the mountain and that this precipitated their desire to build a golden calf. Rashi explains that the nation miscalculated the day of Moses's descent. Moses advised the people that he would return in forty days. Moses was not counting his departure as day one. He meant forty complete days, thus his return would be on the forty-first day, which is the seventeenth of Tammuz. Therefore their calculation was off by one day. Rashi teaches us that as a result of this miscalculation, on the sixteenth of Tammuz, “Satan came and brought confusion to the world, and showed the Israelites a vision of thick darkness.” This caused them to say, \"Moses is definitely dead\" and it ignited their desire to serve other gods.\nUpon analyzing this Rashi, two basic questions must be asked: What compels Rashi to utilize Satan as the vehicle for their confusion? Their mistake in determining Moses's return was based upon their erroneous calculations. This alone should have been sufficient justification for their concluding that Moses was dead and was not returning. Furthermore, Aaron devises different schemes to hinder their attempts to serve different God's. Why didn't he simply advise them of their mistaken calculation? Aaron certainly was aware of the proper count or at the very least recognized their mistake.\nWe must appreciate that the Israelites had recently been liberated from Egypt. In Egypt they were exposed to, and influenced by, the pagan practices of that society. Therefore, they still had an attraction to the primitive, and were still subject to the insecurities of the instinctual part of their personalities. The entire event of Moses ascending the mountain to speak to God was to them, a mystical phenomenon. They were in great awe of this unique experience. Thus, when they saw the thick darkness, rather than attributing it to poor weather conditions, their emotions overwhelmed them. They had visions of Moses' failed mission which image was bolstered by their miscalculation. The Satan, as Maimonides teaches us, is the same as the yetzer harah: man's evil inclinations [the instincts]. Their emotions, which were fostered by their insecurities and primitive proclivities, caused them to conjure these fantastic ominous visions. Chazal teach us that they saw an image of Moses in a coffin. This manifests their regression to the depths of their imagination. They were so overwhelmed by the mystical, that Chazal felt compelled to point out this image, to demonstrate that their total perception of reality was distorted.\nUpon their concluding that Moses had died, the Israelites expressed their desire to make many gods that would lead them. Their need for a god was simply a need for security to fill the void that Moses' ostensible departure created.\nRashi notes that they desired many gods. This again reflects the primitive emotional state. They had desires for different gods, to cater to each of their diverse needs. Their basic insecurities and trepidations were expressed by their desire for different gods, that would satisfy all their personal whims and grant them a sense of security.\nThe insight the Torah teaches with the account of the Golden Calf is extremely relevant. Modern man might think that these are pagan emotions to which he is not susceptible. However, one need only observe Christianity to recognize the strong emotion of idol worship, even today. Christians idolize a physical statue which represents a human being whom they view as God. Objectively, it may seem absurd, but yet its appeal attests to man’s primitive desire for the security of the physical.\nChazal appreciated the strength of these emotions. Rabbi Akiva did not want to learn that the “et\" (together with) of “et Hashem Elokecha teerah\" as including Talmidei Chachamim, because of this emotion: deification of man is idol worship. Rabbi Yishmael argues and states that this word “et” intends to include the Talmid Chacham. The respect the Torah envisions for a scholar is not for the individual per se, but rather the wisdom which he acquired. He is the embodiment of an individual who utilized his Tzelem Elokim for its true objective.\nIt would seem that Aaron also underestimated the strength of these emotions. Aaron recognized their clamor to create new gods as reflective of their primitive emotions. He recognized the futility in trying to demonstrate the error of their calculations. The nation was no longer operating under their intellectual faculty. The primitive behavioral patterns to which they were subject in Egypt were exerting their influence over the nation. The mixed multitude whom departed Egypt with them provoked much of their regression. Rashi advises us that the Mixed Multitude (not descendants of Abraham) used their “magic”(1) to create the calf. In fact, they initiated this entire service and the Israelites followed. The Mixed Multitude had a greater yearning for the security of the physical as a means to relate to God. Therefore, they utilized the “magic” they learned in Egypt. Magic is not some supernatural force. It too requires a discipline, where one learns to switch the apparent relationship between cause and effect to which we are accustomed. It therefore is fascinating because it distracts the observer who is amazed since the feat appears not to function in accordance with standard causal relationships.\nAaron took an active role in the making of the Golden Calf. However, the role Aaron played was really a result of careful analysis. In reality he did not try to facilitate its construction, but rather, attempted to hinder its completion. He analyzed the behavior of the Israelites and tried to deal with them based upon their state of mind. He recognized a step by step regression in their rational faculty as they came under the grip of this overwhelming emotion. Aaron's observations are expressed in a Midrash quoted by Rashi. Aaron observed several things. He saw the Israelites kill his nephew Chur, who tried to rebuke them. He observed and concluded that it would be better if the Israelites transgression was ascribed to him rather than to them. He also concluded that if they built the altar on their own, it would be finished immediately. He therefore undertook its construction hoping to tarry in his work, in order to delay them until Moses arrived. Aaron had recognized that their behavior patterns reflected the powerful sway of their emotions. The first thing the Israelites sought was a substitute leader. This reflected their need for the security of the physical. He requested their ornaments in an effort to appeal to their greed. This was essentially a delay tactic. He assumed that they would be reluctant because he thought that their greed would deter their actions. However, the Torah teaches us “vayitparku”: they readily removed all their jewelry. He thereby recognized and appreciated the overwhelming and dominating effect of these emotions as evidenced by the alacrity with which they responded to his request for their valuables. Thereafter, he observed that they killed Chur. This represented that they were no longer functioning with even a scintilla of rationality. They could not tolerate Chur's rebuke and their murderous actions evidenced their total identification with the calf. He thus observed and concluded that at best, he could only slow their progress. Any attempt by him to halt the construction of the calf would have been futile, and surely would have caused them to regress to the depth of their primitivism.\nA precursory review of his actions would indicate that he was helping them, however a more scrupulous investigation as articulated, reveals his true intentions. He desired that their guilt be ascribed to him in order to assuage the guilty feelings they would experience upon Moses' return. If the Israelites felt absolute culpability because of their actions, their feelings of guilt would render them incapable of doing Teshuva.\nGod still finds fault with Aaron's action. Exodus 32:23 states, \"And when Moses saw that the people were broken loose for Aaron had let them loose for a division among their enemies.\" This criticism is lodged against Aaron for one cannot make compromises with idol worship. The emotion is so powerful that if one allows it to be expressed in his behavioral patterns, it will ultimately dominate his actions and destroy him. Moses, upon his return, took extremely drastic measures. He openly expressed outrage and threw the tablets to the ground and shattered them. He then gathered the Levites, who killed three thousand men. Moses' extreme actions were purposeful to demonstrate that one cannot compromise nor tolerate the emotion for idolatry. The basic philosophy of Judaism is antithetical to these type of emotions.\n(1) Magic is explained as slight of hand by Saadia Gaon. Judaism accepts there are no other powers but God alone.", "pred_label": "__label__POS", "pred_score_pos": 0.8420853614807129}
{"content": "At a very early age, children are beginning to grasp mathematical ‘concepts’ as they endeavour to make sense of the world. In this book, Hannah Mortimer explains these early stages of development and provides practical examples of how early years workers can support and encourage early number work. From the child’s first year, through toddlerhood, the under threes and the Foundation Stage, examples are given that will help you both understand and support children’s mathematical development.\nProblem Solving, Reasoning and Numeracy\n\"The book explores the initial stages of mathematical development and how the early skills develop. It covers areas such as one-to-one correspondence and patterning for the under 3s, learning to count and calculate in pre-school nursery or the reception class. There is also a chapter focusing on supporting children with SEN.A particularly useful inclusion was that each chapter has a section giving advice on how to support children during that specific stage of development.Useful for those who want an overview on how a young child develops mathematical skills and ideas to support development.\nFREE", "pred_label": "__label__POS", "pred_score_pos": 0.6849161386489868}
{"content": "Law360 (September 28, 2020, 1:48 PM EDT) — On Sept. 25, the U.S. Department of Labor issued a notice of proposed rulemaking[1] and request for comments in the Federal Register that seeks to simplify and clarify how to determine whether a worker is an independent contractor or employee under the Fair Labor Standards Act.\nThe DOL has fast-tracked this rule and appears committed to finalizing the proposed regulations before the end of the year.\nPresident Franklin Roosevelt signed the FLSA following the Great Depression and before the U.S. entered World War II when the options for work were largely limited to earning a wage by working for someone else….\nStay ahead of the curve\nIn the legal profession, information is the key to success. You have to know what’s happening with clients, competitors, practice areas, and industries. Law360 provides the intelligence you need to remain an expert and beat the", "pred_label": "__label__POS", "pred_score_pos": 0.9299410581588745}
{"content": "Ensure optimal pump performance with Grundfos Laser Alignment\nWear and tear due to pump motor shaft misalignment shortens pump life and decreases pump performance, resulting in increased running, maintenance and repair costs.\nA pump laser alignment from Grundfos corrects shaft alignment to within a fraction of a millimetre, ensuring optimum pump efficiency and extended service life. Not only do you get a little extra return on your pump investment, you also reduce pump vibration, thereby lowering noise levels.\nWhile primarily targeted at Grundfos long-coupled pumps, Laser Alignment is also recommended for fire systems and may be applied to long-coupled pumps from other manufacturers.\nYour Grundfos laser alignment journey\nWe follow five steps to ensure that your laser alignment process runs optimally.\nInitial contact– When selecting a new pump, consider Grundfos Laser Alignment to ensure correct and optimal performance. Proposal– We supply you with a proposal for laser alignment. Fulfilment– We carry out the laser alignment on an agreed date. Assessment– We check that each pump shaft is perfectly aligned and supply you with a detailed report. Follow-up– We follow up on the performed service to ensure optimal service delivery and satisfactory pump performance.", "pred_label": "__label__POS", "pred_score_pos": 0.9914968013763428}
{"content": "(TNS)—Although electronic filing has drastically cut down the number of errors when filing tax returns, mistakes can still happen. Whether you e-file or mail your taxes in, it’s not hard to imagine that you might botch your tax return — and not realize it until after you file.\nKnowing the common mistakes and the necessary tax forms that are needed when amending a tax return are critical in making the process of correcting a mistake on a return as painless as possible. Understand the steps you need to take to efficiently correct your tax mistakes so you can prevent your refund delivery from being delayed.\nHow to Amend a Tax Return\nIf you catch a mistake after you have already filed your taxes — which might happen if you receive a return or bill from the IRS that wasn’t what you were expecting, you should take action immediately. When you realize that you’ve made a mistake, you can make a tax amendment.\nTo amend your tax return — that is, to make a correction to it — you will need to complete Form 1040X, the Amended U.S. Individual Income Tax Return. Even if you filed your taxes online, the amended tax return form cannot be filed electronically; you must file a paper form and mail it to the IRS. You can use Form 1040X to correct previously filed Forms 1040EZ, 1040A or 1040.\nFile an Amendment before the Tax Deadline If You Owe Additional Taxes\nFinding an error on your own and filing an amended Form 1040X does not extend your tax deadline or forgive additional interest or penalties for extra tax that is due. If you discover that you owe additional tax, you must file the amended tax return form before the tax deadline.\nFile up to 3 Years Later If You Are Owed a Larger Refund\nIf you are owed a larger refund, wait until you receive your original refund before you file the amended Form 1040X. You are allowed to cash the original refund check while waiting for any additional refund.\nYou have up to three years to file Form 1040X. “Any filer looking to claim a refund from a prior tax year must do so within three years from the date they filed their original return or within two years from the date they paid the tax,” said Andrew Oswalt, a certified public accountant and tax analyst for tax preparation software company TaxAct.\nWhen Not to Submit an Amended Return\nNot all errors or mistakes will require an amended return. Common mathematical mistakes are generally caught and corrected by the IRS. Missing schedules or attachments also do not require an amendment, as the IRS will normally just send you a request for the supporting documents.\nIn general, filing electronically and double-checking your work will ensure that your refund arrives in your bank account as quickly as possible. However, should a mistake occur, working within the framework of the IRS guidelines can help you navigate the process of submitting an amended tax return form — and shepherd your tax refund to you quickly and painlessly.\nRuth Sarreal contributed to the reporting for this article.", "pred_label": "__label__POS", "pred_score_pos": 0.5774445533752441}
{"content": "Laparoscopic surgery requires surgeons to view rotated visual feedback of the surgical field. However, systematic assessments of the effects of visuomotor rotations on performance have been controversial. Forty novice undergraduates performed a pointing task in a laparoscopic trainer box while experiencing one of five different visuomotor rotations: 0°, 45°, 90°, 135°, and 180°. Performance was measured using root mean squared error (RMSE). When initially exposed to the visuomotor rotations, participants' performance was superior in the 0° condition when compared to the 45°, 90°, and 135° conditions. The pattern of results observed in the present study were consistent with basic research by Cunningham (1989) that showed the most severe performance decrements for rotations between 90° and 135°. With prolonged exposure to the visuomotor rotations, participants adapted to the distortions. The results of the present study are relevant to the design of laparoscopic training currilicula.", "pred_label": "__label__POS", "pred_score_pos": 0.6206594705581665}
{"content": "/ THE LATEST IN STABILIZATION TECHNOLOGY Increase operating days, Enhance deck safety & speed, Minimise sea sickness\nWave motion is one of the few external forces which has the capacity to negatively impact the operating envelope and profits for offshore boats, regardless of the size of vessel. What’s more, even the most sheltered harbours can suffer unpleasant wave induced motion, that can reduce crew performance, deck safety and increase the time it takes to perform essential tasks. A VEEM Gyro installation can significantly increase the operational availability of these vessels, maximize working revenue, improve\nscheduling certainty, and increase crew endurance, performance and comfort After years of research and development we are delighted to be able to offer our customers the opportunity to join the stabilization revolution that is the VEEM Gyro. Reflecting our unwavering passion for beautiful design and representing a combination of both engineering and manufacturing excellence, the new range offers a genuine revolution in performance compared to existing stabilization systems.\nEnhance deck safety & security\nA VEEM Gyro will significantly improve deck safety and speed by removing the vessel’s rolling motion while underway or at anchor. Less motion will reduce crew sea sickness, reduce fatigue and improve efficiency. Further benefits of a more stable vessel are: increasing crane operating envelopes, maximizing weapons accuracy and achieving safer tender launching and docking alongside fixed and floating facilities.\nIncrease operating days\nWhen profits, project completion dates and construction quality are at the mercy of weather patterns and wave motion, a VEEM Gyro will work to significantly reduce and eliminate downtime due to uncontrollable vessel rolling. This results in increased operating days throughout the year. For Ferries and other passenger vessels – this means more trips and more passengers. For offshore vessels this means continued operation and more effective crew operation.\nMinimize sea sickness\nBy eliminating wave induced rolling motion that causes sea sickness, the VEEM gyro ensures crew members, troops and passengers are comfortable, experience less fatigue, are safer on board and perform more efficiently and effectively both on board and after lea ving the vessel.\nOffshore working vessels carry out critical operations at sea both underway and at rest. A VEEM Gyro installation can significantly increase the operational availability of these vessels, maximize working revenue, improve scheduling certainty and increase crew endurance, performance and comfort. Client teams will experience significantly increased comfort.\nSafer docking alongside fixed and floating facilities due to significantly reduced rolling Safer, faster deck operations Increase crane operational envelope (especially for side mounted cranes) ROV tracking without having to maintain head to sea Reduce thruster and propeller aeration due to rolling More options for heading when handling lines due to less rolling Reduce strain on sea fastenings Increase crew comfort and eliminate sea sickness Decrease crew fatigue leading to better performance Happier, more comfortable client teams Augmented heave compensation systems performance (VEEM Gyro works with heave comp systems without any need for integration or tuning) Can be located off-center line (CL), at any vertical height. Just needs structural mounts to transmit loads into hull.", "pred_label": "__label__POS", "pred_score_pos": 0.667033314704895}
{"content": "According to a new report published by Allied Market Research titled,\nLiqueurs Market by Type and Distribution channel: Global Opportunity Analysis and Industry Forecast, 2017-2023, the liqueurs market was valued at $111 billion in 2016, and is projected to reach $131 billion by 2023, growing at a CAGR of 2.5% from 2017 to 2023. Asia-Pacific leads the liqueurs market in both volume and value terms, and is expected to continue to remain dominant through 2023. Access Full Summary at: https://www.alliedmarketresearch.com/liqueurs-market\nLiqueur is an alcoholic beverage, commonly flavored or sweetened to provide a new texture for the drink. These beverages are divided into three general classesneutrals/bitters, creams, and fruit flavored. Liqueurs are generally made with neutral grain spirits, referring to the flavor being neutral, as the spirits are not finished. The demand for these beverages has changed in the last few years, considering the on/off premises consumption trends.\nIncrease in global young adult demographic coupled with high disposable income fuel the global liqueurs market. However, lack of penetration in the emerging countries, and escalation of sport drink market, owing to health concerns is expected to restrict the market growth in the future. Introduction of healthier varieties of beer and spirits is expected to offer lucrative opportunities for market players.\nBitters is expected to maintain its dominance in the market during the forecast period. This segment held close to two-fifths of the market share in 2016, in value terms, owing to established demand and blend readiness. However, creams are expected to grow with a faster rate due high demand from mixologists and younger demographic during the forecast period.\nIn 2016, retail distribution channels dominated the global market, with nearly one-third share, in terms of volume. Increase in demand for off premises consumption owing to promotion campaigns is anticipated to drive the market growth.\nKey Findings of the Liqueurs Market: In terms of value, creams segment is expected to grow at a CAGR of 2.8% during the forecast period. In Asia-Pacific, India is estimated to be the fastest growing country, in terms of value, growing at a CAGR of 2.7% during 20172023. Supermarket as a distribution channel occupied around one-thirds of the global market share in 2016, in value terms. The U.S. accounted for two-thirds of the North America liqueurs market in 2016, and is expected to grow at a relatively significant CAGR of 2.3%, in terms of value.\nIn 2015, Asia-Pacific and Europe collectively accounted for over three-fifths of the global market, though Europe is expected to grow faster during the forecast period. High growth rates in Germany, Spain, and the UK is estimated to drive this development.\nThe major companies profiled in the report include Bacardi Limited, Beam Suntory Inc., Brown-Forman Corporation, Diageo Plc, Davide Campari-Milano S.p.A., Girolamo Luxardo S.p.A, Lucas Bols B.V., Mast-Jgermeister SE, Pernod Ricard SA, and Remy Cointreau.", "pred_label": "__label__POS", "pred_score_pos": 0.9698678851127625}
{"content": "We Will Guide You Through The Adoption Process\nAdopting a child is a momentous step that is cause for celebration, but the legal aspects of adoption can be complex. It is wise to work with a lawyer who has experience with Georgia adoptions and who has a thorough understanding of Georgia law as it applies to adoption.\nThe law office of Ashley Miles, P.C., in Darien provides knowledgeable legal guidance in a confidential and client-friendly environment. We represent individuals and couples in a wide range of adoptions, including:\nProspective adoptive parents who are using an agency or who already have a private arrangement Prospective adoptive parents who have not identified an agency Stepparents who wish to adopt a stepchild Grandparents who wish to adopt a grandchild Second-parent adoptions for lesbian, gay, bisexual and transgender (LGBT) couples Expectant mothers who want to find a caring home for their newborn Sensitive Representation Provided Confidentially\nWe understand the sensitive and emotional nature of adoption. We are grateful for the opportunity to work with clients in this area, helping them understand the regulations that must be adhered to, as well as the financial assistance that may be available to them.\nIf you are a stepparent, grandparent, sibling or other third party who wishes to adopt a child, the parental rights of the child’s biological parent(s) or legal guardian(s) must terminated. If a legal parent is unwilling to terminate his or her parental rights, you may be able to petition the court to terminate the parent’s rights if it can be shown the parent abandoned the child, failed to support the child, did not communicate with the child for an extended period, or is unfit to be the child’s parent.", "pred_label": "__label__POS", "pred_score_pos": 0.5100593566894531}
{"content": "Discover might be best known for its credit cards, but it also offers deposit products. The online bank’s savings account comes with a solid interest rate and no minimum deposit or monthly fees, making it a fine place to store your emergency fund.\nDiscover Bank earned 4.1 out of 5 stars in Bankrate’s review across its deposit products.\nDiscover savings account rates\nDiscover has only one savings account and it offers the same rate regardless of your balance.\nAccount name APY Minimum deposit Online savings account 1.25% No minimum deposit\nNote: The APY (Annual Percentage Yield) shown is as of May 19, 2020. The APYs for some products may vary by region.\nHow Discover savings accounts compare with top-yielding banks\nDiscover’s savings account offers a solid interest rate, but you can still earn higher APYs elsewhere. The difference in payout isn’t large enough to make switching banks worth your time. But if you’re opening an online savings account for the first time, you can earn more if you open it elsewhere, such as at Vio Bank.\nOther savings options at Discover\nIf you’re looking for other options for your savings, Discover also offers a money market account and multiple CDs that you can consider. The money market account pays a slightly lower interest rate than the savings account and it’s longer-term CDs pay a slightly higher rate.", "pred_label": "__label__POS", "pred_score_pos": 0.7620022296905518}
{"content": "Background: Primary healthcare (PHC) physicians’ attitudes and decision-making contribute significantly to stereotypes and thus to several disparities in provided health care. This study aimed to explore implicit stereotyping among PHC physicians and to identify determinants of physicians’ stereotyping of patients based on the patients’ characteristics and appearance. Methods: This study followed an analytical cross-sectional design. It was conducted during the period from October 2019 till December 2019, and included 250 PHC physicians in Aseer Region, Saudi Arabia. Data were collected using a self-administered questionnaire, which included items concerning physicians’ sociodemographic characteristics and their attitudes toward patient characteristics and patient appearance. Results: Prevalence of stereotyping among PHC physicians was 63.6% with respect to patient characteristics and 57.6% with respect to patient appearance. Stereotyping based on patient characteristics was higher among younger participants, females, those with bachelor’s degrees, those in general practitioner positions, and those with less experience in PHC. Conclusion: Most PHC physicians in Aseer Region are liable to implicit stereotyping based on patient characteristics (e.g., gender and educational level) and patient appearance (e.g., clothing). Therefore, it is recommended to train PHC physicians in cultural competency to reduce unintentional acts of discrimination toward their patients. Keywords— Prevalence, Stereotyped behavior, Primary health care, Saudi Arabia", "pred_label": "__label__POS", "pred_score_pos": 0.9750168919563293}
{"content": "Camden County Man Admits Role in Theft of Government Funds with Stolen Electronic Benefits Machine\nCAMDEN, N.J. – A Camden man today admitted his role today in a scheme to steal hundreds of thousands of dollars in government funds using fraudulently procured electronic benefits transfer (EBT) cards, U.S. Attorney Craig Carpenito announced.\nLuciano Estevez, 50, pleaded guilty by teleconference before U.S. District Judge Renee Marie Bumb to an information charging him with one count of conspiracy to defraud the United States and one count of defrauding the U.S. Department of Agriculture’s (USDA) Supplemental Nutrition Assistance Program (SNAP).\nEstevez and his co-defendants: Jose Garcia, 52, of Camden; Octavio Rodriguez, 51, of Pennsauken, New Jersey; and Juan Melo, 56, of Woodlynne, New Jersey, were previously charged by separate complaints in August 2019 with participating in the conspiracy and defrauding SNAP. Melo previously admitted his role in the scheme when he pleaded guilty on April 28, 2020, to an information charging him with participating in the conspiracy and defrauding SNAP.\nFormerly known as the Food Stamps program, SNAP is administered by the USDA to assist low-income individuals and families with the purchase of groceries and food items. SNAP recipients receive EBT cards, similar to commercial debit cards, to make food purchases. Retailers authorized to accept SNAP benefits have EBT terminals to process the food purchases. Food purchases are made by swiping the EBT card at the terminal, and having customers enter a Personal Identification Number (PIN). The EBT terminal verifies the PIN, determines whether the customer’s account balance is sufficient to cover the proposed transaction, and informs the retailer whether the transaction should be authorized or denied. The amount of the purchase is deducted electronically from the SNAP benefits reserved for the customer and the purchase amount is credited to the retailer’s designated bank account.\nAccording to documents filed in this case and statements made in court:\nEstevez, Rodriguez, Garcia, Melo, and others allegedly targeted low-income individuals who possessed or had access to EBT cards, and unlawfully purchased the cards from these individuals in exchange for cash and controlled substances. Two confidential sources working with law enforcement engaged in 43 controlled transactions involving EBT cards totaling more than $40,500, which they exchanged for cash and controlled substances, including prescription opioids.\nThe defendants used the unlawfully procured EBT cards to purchase bulk goods and food items from large national superstores. These goods and food items were then resold in small convenience and grocery stores owned or affiliated with the defendants or their associates, resulting in a profit for the defendants. Hundreds of EBT cards fraudulently procured by the defendants were used at these superstores, resulting in the misappropriation of approximately $150,000 in government funds.\nEstevez also unlawfully procured an EBT terminal registered to a superstore in Philadelphia, Pennsylvania to use at his small grocery store in Camden, which was not registered as a lawful SNAP merchant in the USDA program. Through this terminal, the scheme netted approximately $110,000 in SNAP funds.\nThe conspiracy count to which Estevez pleaded guilty carries a maximum penalty of five years in prison and a fine of $250,000, or twice the gross gain or loss from the offense. The SNAP fraud offense to which Estevez pleaded guilty carries a maximum penalty of 20 years in prison and a fine of $250,000, or twice the gross gain or loss from the offense. Sentencing is scheduled for Sept. 11, 2020.\nU.S. Attorney Carpenito credited special agents of the U.S. Department of Agriculture-Office of Inspector General, Northeast Region, under the direction of Special Agent in Charge Bethanne M. Dinkins; the U.S. Department of Health and Human Services-Office of Inspector General, under the direction of Special Agent in Charge Scott J. Lampert; the FBI Philadelphia Field Office, South Jersey Resident Agency, under the direction of Special Agent in Charge Michael J. Driscoll in Philadelphia; and the Camden County Police Department, under the direction of Chief of Police Joseph D. Wysocki.\nThe government is represented by Assistant U.S. Attorney Christina O. Hud of the U.S. Attorney’s Office’s Criminal Division in Camden.\nThe charges and allegations against Garcia and Rodriguez are merely accusations, and they are presumed innocent unless and until proven guilty.", "pred_label": "__label__POS", "pred_score_pos": 0.5261216163635254}
{"content": "Description:\nOne of the most difficult challenges that any oil company faces is managing an oil reservoir. Examining the conditions of such reservoirs and monitoring changes are key concerns for managing a well. New drilling technological advancements have allowed operators to save time, reduce operational costs, and lessen their environmental impact.", "pred_label": "__label__POS", "pred_score_pos": 0.999992847442627}
{"content": "You should be able to take Patanol for as long as you need it for symptom relief. The medication has been approved for allergy-related use, so you can use it to relieve seasonal or ongoing symptoms. Talk to your doctor or pharmacist about your use of Patanol and other remedies for your allergy symptoms.\nContinue Learning about Opthalmological Agent\nImportant: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.", "pred_label": "__label__POS", "pred_score_pos": 0.8367446660995483}
{"content": "Wealth creation is a process described by a few essential laws of money. If you live by these rules your chance of financial success is very good. And yet the…\nCategory: Finance\nDr. King believed that social inequality was largely derived from poverty. He was a proponent of financial literacy and achieving financial independence. In fact, in 1966 MLK was a signatory…", "pred_label": "__label__POS", "pred_score_pos": 0.9063789248466492}
{"content": "There will be a Westminster Hall debate on access to and acceptance of cash during and beyond the Covid-19 pandemic on Thursday 3 December at 1:30 pm.\nA House of Commons Backbench Business Debate will take place on 23 April 2020 on the following Motion.\nThat this House\nexpresses grave concern in relation to the Government’s continued inaction in response to the injustice suffered by Equitable Life policyholders, the vast majority of whom have only received partial compensation compared to the confirmed losses directly attributed to regulatory failures; notes the Government’s acceptance of the Parliamentary Ombudsman’s findings to compensate victims in full following the maladministration of Equitable Life; further notes the concern previously expressed by the Public Accounts Committee in relation to the transparency and accuracy of the payments being made to victims; highlights the Government’s failure to fulfil the Committee’s request to publish an intelligible and transparent explanation to policyholders on how to verify the accuracy of the compensation they have received; further highlights examples of grossly inaccurate payments, adjusted only when identified by policyholders, gathered by the Equitable Members Action Group; notes the Government’s continued insistence that there have been no mistakes in the methodology for calculating payments to policyholders; and Further reading\nEquitable Life company website [includes chronology]\nEquitable Life [news: 2019-20]\nEquitable Life: Parliamentary Proceedings [2000- present]\nRelated posts\nHousehold debt: Data on the latest household debt statistics, including net lending, mortgage interest rates and insolvencies.\nCash remains a key payment method for more vulnerable people, but its wider use is in decline, accelerated by the pandemic. How will Government and industry protect access to cash?", "pred_label": "__label__POS", "pred_score_pos": 0.8890994191169739}
{"content": "FOREVER offers a counter-narrative to the anthropocentric way we often describe the city. It acknowledges that our cities, and indeed our world is shared with many other non-human entities, each with their own tendencies and dispositions.\nThe film offers an opportunity to re-frame our relationship with plastic; one that is currently driven by guilt and vilification, into one of empathy and responsible cohabitation. It attempts to shift our attitude towards plastic, a material made invisible through its banality. Instead, the story makes plastic viscerally and emotionally present in the city. Here plastic is no longer the much maligned victim, the neglected creature made to serve us, and discarded when no longer needed. Plastic here flocks together to challenge our world, encouraging a more responsible approach to world-building and world-living, on its way to building one of its own.", "pred_label": "__label__POS", "pred_score_pos": 0.8827667236328125}
{"content": "Once Child Custody has been assigned to one parent, the other has a right to seek Child Visitation. If this is you, it would be in your best interest to contact a Ennis, Texas Child Visitation attorney. These legal professionals are adept with working with judges and the other attorneys to make sure that your right to see your children is assured.\nChild Visitation attorneys are here to argue your case.\nCompetent Child Visitation attorneys in Ennis\nChild Visitation can often be arranged during a meeting between the parents. However, often a judge will have to intervene to settle problems. When this happens, the judge will look to see if there has been any abuse of the child at the hands of one of the parents. This is the situation where an expert Child Visitation lawyer will be highly valuable. These attorneys know the laws that apply to these situations and can help you gather the evidence you need to win or enforce these rights.\nChild Visitation attorneys in Ennis Texas Can procure Your Visitation Rights\nA parent commonly has the right to visit with their child even if they have not been assigned primary custody. If you have been denied this, you should contact a Child Visitation lawyer in Ennis now. Put the law on your side!", "pred_label": "__label__POS", "pred_score_pos": 0.8576148748397827}
{"content": "While LEGaTO mainly focuses on its main use-cases like Smart Home, Smart City or Machine Learning, other applications are also analyzed concerning their performance and energy efficiency, in particular FPGA-centric applications. In cooperation with the Queensland University of Technology (Australia), the research team from Bielefeld University analyzed the acceleration of binary string comparisons on FPGAs using a new approach for a scalable, streaming-based system architecture.\nThe primary focus of the work is to accelerate the calculation of hamming distances, which is the primary source of the load for Locality Sensitive Hashing. This algorithm can be used to compare, e.g., the similarity of DNA sequences. In this application, typically hundreds of queries are compared with large data sets, resulting in billions of calculations.\nAlthough the algorithm for Hamming Distance comparison is rather simple, achieving a highly parallel and scalable implementation was quite a challenging task. The design, described in VHDL, was executed using a Xilinx VCU1525 evaluation board featuring an UltraScale+ VU9P FPGA. A peak throughput of 75.4 billion comparisons per second - of 512-bit signatures - was achieved, using a design with 384 parallel processing elements and a clock frequency of 200 MHz. This makes the proposed FPGA design 86 times faster than a highly optimized CPU implementation. Compared to a GPU design, executed on an NVIDIA GTX1060, it performs nearly five times faster.\nBased on this preliminary work, we plan to port the hardware accelerator to the upcoming Edge Server t.RECS developed within LEGaTO, which will support FPGA modules with UltraScale+ SoC devices. For future work, the design, which was created via low-level tools, could be re-implemented using the high-level LEGaTO stack using the OmpSs programming model or the DFiant HDL approach.\nThe full text of the related publication is open access and can be accessed using the link below:", "pred_label": "__label__POS", "pred_score_pos": 0.7580002546310425}
{"content": "FBXW7 is a tumor suppressor gene responsible for the degradation of several proto-oncogenes. mTOR is one of the substrates of FBXW7-mediated protein degradation, and loss of function of FBXW7 increases the levels of total and activated mTOR. FBXW7 R505C lies within the WD4 repeat region and confers a loss of FBXW7-substrate interaction and impairs substrate degradation by FBXW7, resulting in sustained NICD and MYC expression. Preclinical data have suggested that inactivating mutations of FBXW7 could predict sensitivity to the mTOR inhibitor rapamycin. A single study has reported only limited activity in phase I trials using mTOR inhibitors in patients with advanced cancers including colorectal cancer. The clinical utility remains unknown.", "pred_label": "__label__POS", "pred_score_pos": 0.5114133358001709}
{"content": "The U.S. Department of Energy’s Alternative Fuels Data Center (AFDC) has tracked alternative fueling and electric vehicle charging infrastructure in the United States since 1991. This paper explores the history of the AFDC Station Locator, which was launched in 1999, and discusses the growth of electric vehicle supply equipment. It also looks at how electric vehicle drivers access public charging, and evaluates challenges, gaps, and opportunities facing both electric vehicle drivers and the industry as...\nThis data repository is not currently reporting usage information. For information on how your repository can submit usage information, please see our documentation.", "pred_label": "__label__POS", "pred_score_pos": 0.6582306027412415}
{"content": "In sour gas sweetening applications with large sulfur loadings, amine units are traditionally used for effective bulk sulfur removal. However, most solvents leave behind organic sulfur species such as mercaptans and COS. In some cases, the prevalence of these secondary compounds can cause the treated gas to exceed pipeline sulfur specifications, and may require further polishing. SulfaTrap™ regenerable sorbents demonstrate a high removal efficiency for these compounds, offering an economic solution for the final polishing step to < 0.1 ppm total sulfur.\nSulfaTrap™ sorbent is regenerated via a mild temperature swing using a clean sweep gas stream, and the sulfur compounds adsorbed onto the sorbent are released in the form they were adsorbed (e.g., ethyl mercaptan adsorbed onto the sorbent is released as ethyl mercaptan during the regeneration step). This concentrated mixture of sulfur-laden sweep gas must be further treated to provide a permanent sink for the sulfur compounds.\nMercaptans may be re-treated in the Acid Gas Removal Unit Organic Sulfur may be converted to Sulfur Dioxide (SO2) for consequent removal of SO2 using dry-solid or wet scrubbing\nFEATURES\nHigh selectivity to all sulfur species High removal efficiency - sulfur concentration is reduced to less than 0.1 ppmv High capacity - SulfaTrap™-R5 and SulfaTrap™-R2 achieve up to 20% capacity in regenerable operation Regenerable operation - nitrogen, natural gas, or clean process gas may be used for regeneration", "pred_label": "__label__POS", "pred_score_pos": 0.8819386959075928}
{"content": "EMDR Therapy opens windows in the mind. Imagine rewriting your story. One where YOU decide who you are, how you can be, and how life's challenges affect you. Take a moment to notice how you view yourself in the world. Complete the statement, ”I am_____”. Is your belief negative, such as, “I am unworthy.”, “I am powerless.”, or ”I am unsafe.”? If so, that core belief may be tied to earlier unprocessed memories. What if you could believe something else? What would you rather believe about yourself? I am strong, safe, capable, worthy, lovable, smart… People decide to start EMDR therapy because of anxiety, depression, or pervasive negative beliefs. Francine Shapiro, the originator and developer of EMDR therapy stated that often these experiences are the result of unprocessed memories. When...", "pred_label": "__label__POS", "pred_score_pos": 0.8756483793258667}
{"content": "The countrywide lockdown triggered by global pandemic Covid-19 or Coronavirus has compelled us to stay indoors. It has further led to curtailed newspaper circulation and disruption in news dissemination. In the prevailing situation, pioneering short video platform Likee has extended a helping hand by launching a dedicated dashboard ‘Fight Corona’, providing the latest and authenticated data related to the pandemic.\nLikee, the short video platform by BIGO Technology Pte Ltd, has launched a H5 page, furnishing comprehensive data related to coronavirus, such as number of new cases, total cases, number of recovered patients and the death toll. One tab in the section furnishes state-wise data, giving details from across all states and Union Territories in India. Whereas another tab furnishes details with respect to different countries across the world. While similar data is being given by a few other platforms, the distinguishing factor about Likee dashboard is that the numbers have been sourced from the Union Ministry of Health and Family Welfare along with the World Health Organisation (WHO).\nApart from the numbers, the dashboard also carries latest news snippets related to the pandemic from prominent media organisations. In addition to these, the section also carries videos of Likeers who have given details such as precautions and Dos & Don’ts related to the virus. Attempt has also been made to bust as many as myths related to covid-19 as possible.\nTalking about the initiative, Likee spokesperson Mike Ong said, “Covid-19 has posed one of the biggest challenges before the mankind. The idea behind the dedicated section is to empower people with all authentic and relevant information. Likee is one of the most popular social media apps among youngsters and we are committed to fulfilling our social responsibility.”\nThe short video app has also witnessed a surge in corona-related hashtags, which have been trending on the platform. One of such trending hashtags is #FightCorona, which has clocked more than 102 million views, and the other is #CoronaFactAndRumours, which is aimed at busting the various myths doing rounds on various social media platforms.\nThe global pandemic has spread across as many as 185 countries, with even the most developed ones like America and Italy topping the list. The situation is grim in India too, with the government enforcing a complete 21-day countrywide lockdown.", "pred_label": "__label__POS", "pred_score_pos": 0.8390272855758667}
{"content": "This tent is designed in response to the Ebola epidemic in 2014, which has cost over 11,000 lives. The medical tent can be deployed in cases of hemorrhagic fever outbreaks such as Ebola, and infectious diseases such as cholera.\nThe LegendMEDI answers to the specific challenges when treating hemorrhagic fever patients.\nIt offers solutions such as treatment and isolation rooms for both suspected and confirmed patients.\nThe individual cabins for suspected patients prevent crosscontamination between infected and healthy patients.\nThe medical tent is constructed in a way no (infected) material can accumulate on the surface of the tent, in seams or other parts.\nThe tent is designed to allow freedom of movement and easy operation like opening/closing of the doors with magnetic closures, wearing protective clothing.\nThe special treatment cabins and other accessories are made of PVC coated polyester or polyethylene tarpaulin with noncorrosive accessories, whereby all seams and attachment points which might get in touch with patients, are heat or HF welded.\nAll tent components can be disinfected with chlorine-based disinfectants or other commonly used detergents.\nIt can be erected on various soil conditions and in different climate conditions, from moderate to tropical.", "pred_label": "__label__POS", "pred_score_pos": 0.5219751596450806}
{"content": "Introduction\nTesting for fuels and organochlorinated components in used engine oil regularly can predict when equipment maintenance is required preventing unnecessary oil changes and costly engine damage. This presentation will explain a novel approach to measuring total organochlorides and fuels in oil in a tandem analysis requiring no sample preparation and a run time of ~3.5 minutes.", "pred_label": "__label__POS", "pred_score_pos": 0.6435756683349609}
{"content": "10/28/2020\nTensions are high, and turmoil is surrounding us. The American Psychological Association recently reported that stress levels are significantly higher compared to previous years. While some stress is good, chronic stress can be detrimental to our bodies. Stress can lead to fatigue, inflammation, headaches, muscle tightness, neck, back, and shoulder pain.\nMany wait to turn to physical therapy as a follow-up after a surgery, accident, or injury, but did you know that you can turn to physical therapy for stress now?\nWorking with a physical therapist can help you manage your stress and its symptoms. We reduce tension in the neck and back through powerful interventions and educate you on how to perform these at home. Let us use our very own virtual reality relaxation program and heart rate variability training to provide that feeling of much-needed rest. Breathing can significantly decrease overall stress. Allow us the opportunity to teach you breathing techniques and tips you can use daily for the rest of your life!\nIf you have a hard time coping with stress and its impact on your body, schedule an appointment, and we will help you on your journey to well-being.", "pred_label": "__label__POS", "pred_score_pos": 0.9478005170822144}
{"content": "Here are some simple dietary steps and nutritional tips from Francesca that you can use to support your immune system. Vitamin C – a powerful antioxidant that supports your body’s ability to fight viruses. Foods rich in vit C include citrus, berries, peppers, kiwis, pomegranate. Vit D – supports and regulates the immune system. Primarily…", "pred_label": "__label__POS", "pred_score_pos": 0.9701602458953857}
{"content": "For the first time in its history, the World Youth Alliance North America (WYANA) staff traveled outside of New York City limits to host an\nEmerging Leaders Conference (ELC). The first conference outside of New York, and the first annual conference at Benedictine College, in Atchison, Kansas, was held the weekend of October 27 th, 2017.\nThe ELC opened on Friday, October 27\nth, with a lecture on human anthropology given by Benedictine’s Dr. Andrew Salzmann. Dr. Salzmann sought to identify what it means to be a human person. He spoke in-depth on the nature of individuals and the significance of the human body in mediating human intersubjectivity. Weronika Janczuk, regional director for WYANA, continued this train of thought with the opening lecture on Saturday, October 28 th. She highlighted the essence of the human person, and contemporary ideological challenges to a healthy understanding.\nFollowing Weronika, Dr. Sharon Sullivan of Washburn University, an expert on women’s issues with a specific focus on sex trafficking, offered a moving presentation on the absolute violation of the human person through the prevalence of sex and labor trafficking.\nAfter Dr. Sullivan, brief introductions on person-centered solutions were given by representatives from the Brilla Charter Schools Network, WYA, and FEMM. Tess Lane of the Brilla Charter Schools Network introduced the charter school structure and partnership with the Seton Teaching Fellows program, while Jonathan Scrafford, MD, Ob/Gyn, introduced the medical protocols underlying the work of WYA’s affiliate women’s health program, FEMM (Fertility Education & Medical Management). Julia Kenney, director of operations for WYANA, spoke about the Human Dignity Curriculum (HDC) and its place in curriculum development.\nEach representative spoke on the history of their foundation and emphasized the necessity of their work regarding the promotion of the dignity of the human person. The conference concluded with Weronika engaging in conversation with the attendees about how the mission of WYA could be continued at Benedictine.\nThe conference boasted approximately 40 attendees total. Students in attendance were highly motivated by the mission of WYA, and many have already expressed interest in a desire to learn more. Amongst these students were Sophia Glaser and Katie Greenwood (a former WYA intern). Katie and Sophia are both seniors at Benedictine, and they have begun the process of establishing a WYA chapter at Benedictine with the support of Dean Joe Wurtz (dean of students) and Dr. Jeremy Sienkiewicz (professor and faculty sponsor of the WYA chapter). WYA is excited to see Benedictine embrace its mission.\nAdditionally, progress was made in the local Atchison area for implementation of WYA chapters and projects. Benedictine College wholeheartedly welcomed WYA, and dates are currently being looked at for next year’s ELC at Benedictine.", "pred_label": "__label__POS", "pred_score_pos": 0.6288328766822815}
{"content": "I spent a half hour this morning being interviewed by my dear friend, Debbie Lousberg, a career coach, for the “Success Journeys” portion of her Blog Talk Radio program, “There’s a U in Success.” You can listen to us here.\nIn this interview, I define success as having three parts:\nTo be self-aware (to understand your own strengths, weaknesses, thoughts, beliefs, motivation, and emotions) To conduct yourself with integrity (honesty, decency, truthfulness) To contribute to making the world a better place (may not be through work)\nI also make three recommendations to help cultivate self-awareness:\nCultivate a spiritual practice that quiets the mind, preferably daily. This might be prayer, meditation, journaling, chanting—anything that leaves you more grounded than when you started. If you can afford it, consider working with a therapist or with a spiritual director. Ask other people—trusted—how they perceive and experience you. Other people may see something in you that you haven’t seen in yourself.", "pred_label": "__label__POS", "pred_score_pos": 0.926506757736206}
{"content": "This book presents a comprehensive mathematical theory that explains precisely what information flow is, how it can be assessed quantitatively – so bringing precise meaning to the intuition that certain information leaks are small enough to be tolerated – and how systems can be constructed that achieve rigorous, quantitative information-flow guarantees in those terms. It addresses the fundamental challenge that functional and practical requirements frequently conflict with the goal of preserving confidentiality, making perfect security unattainable.", "pred_label": "__label__POS", "pred_score_pos": 0.9944751858711243}
{"content": "Abstract\nBackground: The tropical Andes and Amazon are among the richest regions of endemism for mammals, and each has given rise to extensive in situ radiations. Various animal lineages have radiated ex situ after colonizing one of these regions from the other: Amazonian clades of dendrobatid frogs and passerine birds may have Andean ancestry, and transitions from the Amazon to Andes may be even more common. To examine biogeographic transitions between these regions, we investigated the evolutionary history of three clades of rodents in the family Echimyidae: bamboo rats (Dactylomys-Olallamys-Kannabateomys), spiny tree-rats (Mesomys-Lonchothrix), and brush-tailed rats (Isothrix). Each clade is distributed in both the Andes and Amazonia, and is more diverse in the lowlands. We used two mitochondrial (cyt- b and 12S) and three nuclear (GHR, vWF, and RAG1) markers to reconstruct their phylogenetic relationships. Tree topologies and ancestral geographic ranges were then used to determine whether Andean forms were basal to or derived from lowland radiations. Results: Four biogeographic transitions are identified among the generic radiations. The bamboo rat clade unambiguously originated in the Amazon ca. 9 Ma, followed by either one early transition to the Andes (Olallamys) and a later move to the Amazon (Dactylomys), or two later shifts to the Andes (one in each genus). The Andean species of both Dactylomys and Isothrix are sister to their lowland species, raising the possibility that highland forms colonized the Amazon Basin. However, uncertainty in their reconstructed ancestral ranges obscures the origin of these transitions. The lone Andean species of Mesomys is confidently nested within the lowland radiation, thereby indicating an Amazon-to-Andes transition ca. 2 Ma. Conclusions: Differences in the timing of these biogeographic transitions do not appear to explain the different polarities of these trees. Instead, even within the radiation of a single family, both Andean and Amazonian centers of endemism appear enriched by lineages that originated in the other region. Our survey of other South American lineages suggests a pattern of reciprocal exchange between these regions - among mammals, birds, amphibians, and insects we found no fewer than 87 transitions between the Andes and Amazon from Miocene-Pleistocene. Because no clear trend emerges between the timing and polarity of transitions, or in their relative frequency, we suggest that reciprocal exchange between tropical highland and lowland faunas in South America has been a continual process since ca. 12 Ma.\nKeywords Amazonia Andes Biogeography Divergence timing Echimyidae Ex situ diversification Molecular phylogeny Neotropics Rodentia South America ASJC Scopus subject areas Ecology, Evolution, Behavior and Systematics", "pred_label": "__label__POS", "pred_score_pos": 0.8531762957572937}
{"content": "I love the idea of being a lady, but I ain't got time for grace and daintiness. I'm a Millennial, so they say.\nI'm putting myself in the shoes of Meghan Markle and I'm overwhelmed with despair. The prospect of taking lessons in etiquette as a fully fledged adult seems unnecessary. The first thing I want to do when I see a chicken wing is pick it up, and gnaw it to the bone like Viola in the movie\nShe's the Man. Sure, I'll use a napkin – to mop up the lashings of grease spread freely around my mouth like a clown's lipstick. Old habits die hard.\nI've always felt free to justify my laziness in one of two ways: I'm hungry, or \"this is superficial and pointless\". It's time to face reality. Good manners will never be outdated. I can't stand it when people spit in my face while they talk, who bang the table or poke me with their elbows. Likewise, I'll often catch myself appreciatively remarking \"chivalry is not dead\" when a man opens a door for me. Hello, Mr Darcy.\nOkay, so times have changed. Dresses don't need to hit the floor anymore, shoes and ankles are outrageously visible, and we've ditched the gloves and hats. But hell, I still love a high tea experience (if only to smash out a few scones just visible under mountains of whipped cream). Surrounded by pastries and sandwiches, I found myself in the most tolerable setting in which to collect some tips from Zarife Hardy, director of the Australian School of Etiquette, at the Langham hotel in Sydney.\nHardy's myth-busting astounds me. I'm already embarrassed about not knowing that cutlery should be avoided at all costs during afternoon tea. Scones are to be broken with the hands, as should bread at any meal. Turns out, having my pinkie up when holding my teacup can be rude. The cup should only be held using the thumb and index finger, neither of which sit on top of the handle. Tea should be stirred with a teaspoon backwards and forwards, not in a circular motion. I feel rude doing it, but I should be looking\ninto the teacup while sipping, not beyond it and into the eyes of my chattering friend. Mind. Blown.\nAlready, I see why people hate etiquette. It's humiliating to realise your own ignorance. Hardy explains that \"the hardest job kids face today is learning good manners without seeing any\". If we don't use a napkin when eating at home, how are we to know the way it should remain folded on one's lap? Only the corner is to be used to gently wipe the face; it should be placed on the back of one's chair if nature calls, and only finds its way onto the tabletop when the meal is over.\nI'm not about to go blaming my mum for my uncertainty. I was raised to eat dinner with the family, hold my knife and fork properly, elbows off the table, chew with my mouth closed, blah blah blah. In fact, I am grateful we're not living in the 1800s anymore, when I would've had to sit at the table with a boiled egg behind my bottom so I'd \"use my core\" rather than sink back into my chair; or have books underneath both arms so that my arms remained glued to my side. The know-how is not the main issue anyway.\nIt's the irregularity of my employment of etiquette that makes it so inconvenient. I have to think. It's not automatic. Crisp linen and multiple sets of cutlery are the usual reminders I'll need to put on a show of my best manners. The very fact that it feels like a performance is what makes poise and primness look silly. I should uphold a uniform standard of behaviour. Manners are not just for the job interview, but for the office kitchen as well.\nReflecting on my new knowledge, I think there's an important distinction to make between formal etiquette and good manners. I think it's forgivable to break certain specific rules – sometimes I might hold my champagne in the right hand when greeting people, rather than in the left. The more general, instinctive rules are valuable, such as never stuffing more food into my gob than I can swallow after four to five chews.\nIt's probable that I'll still be scooping my peas rather than spearing them three-at-a-time with my fork. Changes I\nwill be making include focusing on the art of conversation, confidently balancing questions with sufficient answers. The ability to make authentic small talk is a depressingly vital skill. \"Good manners will open doors that the best education cannot,\" states Ms Hardy.\nHaving said that, Queen Victoria had the milk poured first when serving her tea, so that the clay cups didn't break from the sudden heat. If Victoria can justify her customs with practicality and efficiency, why can't I? I'll bet she never had to use chopsticks or take an urgent phone call.\nAll I know is, the Queen and I can agree that Earl Grey tea is the bomb.", "pred_label": "__label__POS", "pred_score_pos": 0.6395478844642639}
{"content": "The Fifth Circuit has followed the Second Circuit's ruling in\nCroll v. Croll and has ruled that a \"ne exeat\" right does not constitute a \"right of custody\" for the purposes of the Hague Convention on the Civil Aspects of International Child Abduction. ( Abbott v. Abbott, handed down on 9/16/08).\nThe case concerned a British father and American mother who lived with their child in Chile. When the parents separated the Chilean courts awarded sole custody to the mother with visitation rights to the father and entered a subsequent order (the “ne exeat order”) prohibiting the child's removal from Chile by either parent without their mutual consent. The mother concededly breached that order by taking the child to Texas and keeping him there without the father's consent and without notice whilst the parties were in the midst of disputes over visitation and other issues. The Hague Convention provides the remedy of return of a child only if the child's removal or retention from its habitual residence breached “rights of custody attributed to a person.” The Fifth Circuit was required to determine whether to follow the three federal appellate courts that have determined that ne exeat orders and statutory ne exeat provisions do not create “rights of custody” under the Convention (Fawcett v. McRoberts, 326 F.3d 491, 500 (4th Cir. 2003); Gonzalez v. Gutierrez, 311 F.3d 942, 948 (9th Cir. 2002); Croll v. Croll, 229 F.3d 133, 138–39 (2d Cir. 2000)) or whether to follow the Eleventh Circuit which has reached the opposite conclusion. (Furnes v. Reeves, 362 F.3d 702, 719 (11th Cir. 2004)). The Eleventh Circuit's view has received further support in the First Circuit in Whallon v. Lynn, 230 F.3d 450, 458 n.9, 459 (1st Cir. 2000) and Croll has been criticized in most of the academic literature.\nThe Fifth Circuit also noted that the Furnes court had “catalogued” the foreign opinions on the issue, noting that courts in the United Kingdom, Australia, South Africa, and Israel have held that ne exeat rights do constitute “rights of custody” under the Hague Convention, while Canadian and French courts have reached the opposite conclusion. Furnes, 362 F.3d at 717–18.\nThe decision of the Fifth Circuit is that it follows the majority rule. It held that:\n“We find persuasive Croll's reasoning that the Hague Convention clearly distinguishes between “rights of custody” and “rights of access” and that ordering the return of a child in the absence of “rights of custody” in an effort to serve the overarching purposes of the Hague Convention would be an impermissible judicial amendment of the Convention. We hold that ne exeat rights, even when coupled with “rights of access,” do not constitute “rights of custody” within the meaning of the Hague Convention. The Hague Convention provides a remedy of return only for a parent who holds “rights of custody.” The father in this case did not hold such rights.\"", "pred_label": "__label__POS", "pred_score_pos": 0.696590781211853}
{"content": "Strategic Instincts: The Adaptive Advantages of Cognitive Biases in International Politics In\nStrategic Instincts Dominic Johnson shows how an evolutionary perspective offers the crucial next step in bringing psychological insights to bear on foundational questions in international politics.\nAbstract\nA widespread assumption in political science and international relations is that cognitive biases—quirks of the brain we all share as human beings—are detrimental and responsible for policy failures, disasters, and wars. In Strategic Instincts, Dominic Johnson challenges this assumption, explaining that these nonrational behaviors can actually support favorable results in international politics and contribute to political and strategic success. By studying past examples, he considers the ways that cognitive biases act as “strategic instincts,” lending a competitive edge in policy decisions, especially under conditions of unpredictability and imperfect information.\nDrawing from evolutionary theory and behavioral sciences, Johnson looks at three influential cognitive biases—overconfidence, the fundamental attribution error, and in-group/out-group bias. He then examines the advantageous as well as the detrimental effects of these biases through historical case studies of the American Revolution, the Munich Crisis, and the Pacific campaign in World War II. He acknowledges the dark side of biases—when confidence becomes hubris, when attribution errors become paranoia, and when group bias becomes prejudice. Ultimately, Johnson makes a case for a more nuanced understanding of the causes and consequences of cognitive biases and argues that in the complex world of international relations, strategic instincts can, in the right context, guide better performance.", "pred_label": "__label__POS", "pred_score_pos": 0.6289194822311401}
{"content": "Would you like to download our mobile app from the App Store?Download\nOur Tax Investigations & Dispute Resolutions team assisted in closing a long-running Inheritance Tax (IHT) enquiry into the Estate of our client’s deceased mother. By completing a detailed case review and collating a comprehensive response to HMRC, we were quickly able to close the enquiry and displace HMRC’s assertion that up to £300,000 IHT was payable.\nA potential client was referred to Simmons Gainsford LLP’s Tax Investigations & Dispute Resolutions Team. The client was the executor of a parent’s Estate had entrusted his family’s lawyer to progress an HMRC Inheritance Tax enquiry, which had been running for over two years prior to our initial discussion. As the investigation had been running for such a period, our client sought specialist advice in order to find a way to move the enquiry to closure.\nFollowing Simmons Gainsford’s engagement, our team conducted a detailed and thorough review of case correspondence and supporting documentation to identify the main areas of dispute.\nWhilst the Estate itself did not appear to be complex as the main asset was a sole UK rental property, the HMRC officer was asserting that approximately £300,000 additional Inheritance Tax was payable. The two main issues were the deductibility of a number of loans to the deceased in her final years by her two sons, and the proportion of property ownership chargeable to the deceased.\nOnce we had a firm understanding of the dispute, we discussed matters with our client in detail to explaining the current position and gain further background. As HMRC had raised a protective charge on the property held by the Estate, the assets were still unable to be distributed.\nOur team prepared a comprehensive response to address all open disputes. We identified deficiencies in HMRC’s position and arguments, and provided extensive arguments supported by relevant case law and additional documentary evidence.\nOur response addressed and satisfied all risks that the HMRC officer was concerned with. HMRC agreed with the position that we laid out and swiftly closed the enquiry with no additional tax payable by the Estate.\nBy conducting a detailed review of the matters in hand, working closely with our client, and tailoring a comprehensive response to HMRC, out team was successful in closing a long-standing investigation with a single piece of formal correspondence.\nThis case highlights how HMRC investigations may sometimes grind to a halt and that a fresh set of expert eyes may help bring matters to a close. It also highlights that HMRC are willing to listen and change their mind on their assertions once detailed arguments and supporting documentation is provided.\nOur client was ecstatic with our successful result and that that the assets of the estate could now be distributed following such a long dispute and shared his thoughts, below;\n“\nWell done to you and the team, you have our appreciation and highest respect for the efficiency, expertise and professional way the whole matter has been handled.”\nHow can Simmons Gainsford help?\nOur team includes many specialists and ex-HMRC personnel. We are able to undertake a review of your specific circumstances and advise on how to navigate through complex HMRC enquiries.\nIf you require assistance, please do not hesitate to contact the head of our Tax Investigation and Dispute Resolution Team, Anthony Rose on\nAnthony.rose@sgllp.co.uk or telephone 020 7447 9000.", "pred_label": "__label__POS", "pred_score_pos": 0.6745247840881348}
{"content": "Detox Cleanse $49.95 Detox Cleanse has been developed to support gastrointestinal health using all-natural ingredients to detoxify the colon and optimize digestion. This can provide rapid relief from symptoms such as bloating, fatigue, headaches, and constipation. Expertly formulated Detox Cleanse will help: Detoxify your system Aid weight loss Alleviate constipation Improve digestion Reduce bloating Boost energy Improve overall feeling of wellness\n54 in stock\nThe average modern diet is often not in sync with the natural functioning of our bodies. This can lead to uncomfortable digestive issues and even cause various illnesses associated with poor gut health. When your bowel is not functioning optimally, this can lead to problems such as bloating, fatigue, constipation, headaches, and a general sense of feeling “unwell.”\nAt Terra Health Essentials we have developed an all-natural solution to help you to cleanse your system, overcome these symptoms, increase your energy levels, and feel like yourself again.\nDetox Cleanse is a pain-free method of detoxifying your gut to provide a healthy and clean environment for your colon to function properly. Main Ingredients:\nThis specialized, proprietary blend will naturally detoxify your body by flushing out any toxins. This formula also contains Psyllium Husk — an excellent source of fiber that can alleviate constipation, aid weight loss, and even lower cholesterol.\nList of Ingredients: 334mg Proprietary Blend Psyllium Husk Gotu Kola Milk Thistle (seed) Garlic (bulb) How to Use: 1 capsule per day after a meal", "pred_label": "__label__POS", "pred_score_pos": 0.5001332759857178}
{"content": "The Social Change Diaries podcast is dedicated to exploring pivotal aspects of the social change sector, from the perspective of the experts who live and breathe the work of changing our world for the better. The show is hosted by Wakeman Agency CEO, Vanessa Wakeman. Each season is dedicated to a specific theme that is at the forefront of the sector. The theme for Season 5 is The Aftermath of Crises. The year 2020 represents a profound moment in human history, as the global pandemics of COVID-19 and racism have sparked massive waves that herald a new era of change. In this season, Vanessa speaks with leaders in various sectors about the impact and aftermath of this moment on a range of issues, including civil rights, philanthropy, the media and more, focusing on what the future may hold, as we navigate consistent shifts into “next normals”.\nAt no point in recent history has civil rights been so loudly at the forefront of everyday life, in multiple ways. The tidal wave of shared trauma ushered in by the Covid-19 pandemic and the recent slew of racially motivated murders presents glaring questions and implications around civil rights and how this moment can be a springboard for true systemic change. As an expert in policies, laws and all facets of civil rights, Ms. Lieberman discusses the implications of this time period, how it relates to other historical moments in civil rights and the myriad of nuances that comprise this complex, but powerful moment in human history.\nIn this episode, Global Press Founder, Cristi Hegranes, shines a powerful light on solutions to institutional, ingrained problems that underly today’s news media. She outlines key differences between action driven reporting and its more informative, impactful alternative: consequence driven reporting. Learn why trained local journalists, equipped to provide precise narratives that accurately inform listeners, represent a pathway to truly educating people in a non biased way, about important global issues.\nHow nonprofits can successfully and efficiently secure corporate giving is a more important issue than ever before. This conversation with Becky Ferguson, VP of Global Philanthropy for pioneering powerhouse, Salesforce, provides key insights and concrete information for nonprofits to consider when strategizing, securing and sustaining corporate partnerships.\nFuturist Rohit Talwar on Thinking the Unthinkable and Reframing Positions of Power to Positions of Responsibility\nWe kick off our 5th season with Rohit Talwar, the CEO of Fast Future, a UK based research and insights business that specializes in the fields of futures and foresight. In this dialogue, Rohit and Vanessa discuss the implications of the groundbreaking events that have occurred in the first half of 2020.", "pred_label": "__label__POS", "pred_score_pos": 0.8437085747718811}
{"content": "A significant amount of ferrous metal found in appliances is recycled and used for different items. You can melt and reuse metal several times without altering its properties. Recycled metal is used in things people use every day, like soda cans and vehicle engines. Here's a breakdown of the top benefits of scrap metal recycling. Reducing Emissions Scrap metal recycling uses less energy and is more efficient than refining raw materials using conventional mining processes.\n20 July 2020", "pred_label": "__label__POS", "pred_score_pos": 0.9867907166481018}
{"content": "Bareilly: The Uttar Pradesh State Road Transport Corporation (UPSRTC) has made it mandatory for roadways buses covering more than 300 km to be checked for safety measures and undergo fitness analysis before a long route haul.\nUPSRTC managing director Raj Shekhar has directed all regional officials across the state to ensure mandatory checking of long-route roadways buses and that a record of the same be maintained.\nThe assistant regional managers and foremen, have been asked to cross verify and ensure compliance of the orders. They have to ensure that the vehicle are checked in accordance with prescribed rules ahead of each journeys.\nOfficials at UPSRTC said safety measures are being taken up following the roadways bus accident on Yamuna Expressway that left 29 people dead.\nSpeaking with TOI, Bareilly regional manager SK Banerjee said, “A circular has been recently issued where we have been directed to ensure that corporation buses, especially the ones plying on long routes, meet certain safety measures and are fit to cover the distance. Before a bus is sent on the journey, the vehicle are to be checked for safety measures including installation of vehicle tracking system, speed governors, fire extinguishing device, first aid box.\"\nHe further added,\"The vehicle must also undergo proper fitness test which will include checking of tyres, window panes, emergency gates, lights, wipers, driver’s documents, etc. The air-conditioned Volvo, Shatabdi and Janrath buses must also have a glass-breaking hammer. The vehicles are to be mandatorily checked for these before a journey and we have to maintain a record of the vehicle stating whether it meets the guidelines or lacks any of these.”\nRegional manager added, “Though installation of first aid kits, fire extinguishing devices, glass breaking devices, was already in place, the corporation is now gearing up to ensure that the buses comply with the given guidelines. Apart from this, camps for health and eyesight checkups are being organized for bus drivers. The frequent health checkups have also been made mandatory for drivers who are 50 or more years old.\nAccording to information from UPSRTC, the corporation currently operates 12,287 buses across the state. Under Bareilly division, 659 buses are operated and of these, 128 buses, including AC and ordinary buses, ply on long routes.", "pred_label": "__label__POS", "pred_score_pos": 0.7134188413619995}
{"content": "Thank you for your work this year, and for never giving up on making a difference for your students – especially now, in this convergence of two significant moments in time. We have been working to provide a new kind of school, and planning for an uncertain future during the COVID-19 pandemic. On top of that, the nation saw the intentional murder of George Floyd by a white police officer in Minneapolis, and national protests have called for an end to anti-Black racism and police brutality. These events have highlighted the importance of our role as educators, and the power that we have to fight for a better future for students in our community.\nThe BEA Narrative on Public Education states that, ”our ultimate goal as a union of educators is the physical, social, emotional, and intellectual nourishment of our students.” We cannot achieve this goal without advocating for educators, and we cannot achieve this goal without advocating for racial and social justice. As a predominantly white organization of educators, we need to examine our own educational practices, as well as systemic policies, that harm students and staff. We must evaluate and disrupt the systemic ways that Black and African American students, staff and families are marginalized in our schools and communities.\nAs a union, this is our responsibility. The BEA Executive Board will be reviewing and revising the BEA Narrative, to be more explicit about our commitment to fighting institutional racism within our schools and our union. The BEA Racial and Social Justice Task Force will meet during the summer to map out specific actions that align with our commitments. We stand in support of our members who are Black and African American, as colleagues, allies and accomplices. We will continue to support and promote Black student-led protests and actions throughout the summer. We support mandatory antiracism, anti-bias training for all staff. We advocate for the recruitment, hiring and attention to retention of Black, Indigenous and People of Color (BIPOC) in the Beaverton School District. We support the immediate implementation of more culturally responsive curriculum, and improving the cultural competency of all staff. We encourage white educators to be anti-racist, interrupt bias, hold colleagues accountable, and prioritize the safety and well-being of BIPOC colleagues and students. We also encourage white educators to access the list of books, podcasts, and movies that OEA has put together to learn and grow in your understanding of anti-racist allyship, and engage in the work.\nI look forward to continuing to work with you all to build a strong union, a strong school district, and a strong community. Have a safe, healthy and restful summer.\nIn unity,\nSara Schmitt BEA President", "pred_label": "__label__POS", "pred_score_pos": 0.5339599847793579}
{"content": "Diversity Mission\nThe Department of Psychology is situated within the University of Hawaiʻi at Mānoa, a Hawaiian place of learning and one of the most ethnically diverse universities in the United States. The uniquely diverse cultural context of Hawaiʻi informs the Department’s priority on representing and understanding the unique ethnic composition in our community.\nOur Department is committed to promoting and supporting diversity across all levels. We define diversity broadly to include: race and ethnicity; national origin; indigenous heritage; gender identity; sexual orientation; age; dis/ability, socioeconomic, immigrant, or first language status; body size; religion or spirituality; and other human attributes with significant implications for social identity and historical experience. We seek to have equitable representation and treatment of these groups.\nWe actively recruit and educate diverse students, faculty, and staff and proactively acknowledge and engage with our location to immerse them in a multi-ethnic/cultural environment. We recognize that an intentionally diverse workforce is essential for serving the needs of our diverse state. Individuals who share these intentions and aspirations are encouraged to join us in our efforts to be a model for inclusive excellence.\nStatement on Anti-Black Racism and Violence\nThe people of the U.S.A. are living in what has aptly been called a “racism pandemic.” Racism has been a persistent and debilitating problem for racial minorities from the founding of this country, and disproportionally affects Black people in all facets of life. Racism is associated with poor outcomes in both physical health and psychological wellbeing. Parents raising Black children must send them into a world that is unsafe, unfair, and unjust. This year, we have seen the deeply horrifying and unjustifiable murders of George Floyd, Rayshard Brooks, Tony McDade, Breonna Taylor, and other victims of police brutality and racist violence. These victims add to the list of countless other innocent Black lives that have been gruesomely taken and willfully ignored by the justice system throughout American history.\nOn top of this racism pandemic, Americans are now also facing a health pandemic that has predictably, disproportionally affected the health of Black people. During the COVID-19 pandemic, Black communities, particularly Black LGBTQ+ communities, have suffered greater losses than other groups due to underlying healthcare and socioeconomic disparities.\nWe, the Department of Psychology at the University of Hawaiʻi at Mānoa, stand in solidarity with the Black community against all forms of individual, cultural, and systemic racism and discrimination. We add our voices to those who are calling for an end to racism, racial violence and police brutality in the United States and around the world. We acknowledge with heavy hearts the pain that the families and the communities of these victims are experiencing. We recognize the importance of reflecting on and ameliorating our own role in relation to perpetrating these issues, whether by action or inaction, intentional or non-intentional, and the importance of educating ourselves and others to address racism and inequality directly and explicitly. In that spirit, we admit that the late timing of this statement, following months of national attention on the civil rights atrocities perpetrated on Black people, communicates a failure to prioritize this issue on the part of our department. We intend to live up to our words by reflecting on our own apprehensions and slow action—and correcting them in the future.\nWe know that this statement is not enough on its own and that this problem will continue if not addressed with action. Accordingly, the department is increasing our attention on incorporating anti-racist perspectives and policies. We acknowledge that our current efforts do not focus on addressing anti-Black racism specifically, and pledge to also concentrate future efforts on attending to anti-Black racism and violence, in course curriculum and hiring and admissions processes. In addition, we plan to provide training for those interested in writing anti-racist legislation testimonials, invite diversity speakers to speak on Black Lives Matter and anti-racism, and creating safe spaces for students from historically marginalized groups to share the racism they experience. A few graduate students have also started a live resources document related to structural inequalities (either learning about the topic or resources for coping with racism) to which we invite our community members to contribute. We hope that our organization will be part of a collective voice that engages in sustained action demanding safety, justice, and peace for all Black people and by extension, all of us. We pledge to track and be transparent about our progress in promoting anti-racism in our department, and invite community members to provide feedback at any time.\nOctober 31, 2020 The Department of Psychology at the University of Hawaiʻi at Mānoa", "pred_label": "__label__POS", "pred_score_pos": 0.6445287466049194}
{"content": "The U.S. Securities and exchange commission (SEC) continues to make major moves pertaining to the cryptocurrency industry. Of late, the SEC has taken another step towards streamlining the process to settle digital asset securities by shortening four-step processes to three to mitigate operational risks for brokers and dealers.\nAccording to a no-action letter made public on September 25, the SEC has stated that it won’t penalize any broker-dealer that operates an alternative trading system (ATS) that trades digital asset securities if they comply with the new guidelines.\nThe regulator states that there is demand amidst ATS to follow a streamlined system especially for cases where there is no custody over the trader assets.\nUntil now, most ATS followed the four-step process where first the buyer and seller send orders to the ATS, then the ATS matches the orders followed by which the ATS notifies both the parties about the matched trade and finally, the transaction is settled bilaterally among the parties or their respective custodians.\nHowever, the Financial Industry Regulatory Authority (FINRA) wants to see more clarity in cases in which the broker-dealer may not take physical custody of the asset.\nSome felt that the four-step process is too risky, and hence the ATSs have requested that the process be made more streamlined.\nThe no-action letter explains that the new process includes:\nStep 1: both the buyer and seller place their orders with the ATS, notify their custodians about their orders, and instruct them to settle the transactions in accordance with the terms of their orders when the order is matched. Step 2: The ATS matches the order. Step 3: The ATS notifies the buyer, seller, and custodian of the matched order and the custodians carry out the trade-in accordance with the instructions.\nAccording to paragraph (b) of Rule 15c3-3 of the SEC (the Customer Protection Rule), Broker-dealers must “obtain and maintain physical possession or control of all fully paid or excess margin securities carried by a broker-dealer for the account of customers.”\nGenerally, this rule is a safeguard in case the ATS fails, which protects customers from losses or delays in accessing their security. But things are complicated when this involves digital assets.\nThe SEC has stated that those using the new model will not face any enforcement action related to the Customer Protection Rule.\nFurthermore, the letter adds that those seeking to comply with the new process have addressed concerns regarding their custodial roles and noted that they operate with at least $250,000 in capital, and also inform their customers that the broker-dealer operator cannot guarantee or take responsibility for settling trades.\nThe broker-dealers must also ensure that they assess security tokens’ registration with the SEC and that the assets comply with federal law.\nHowever, the SEC highlighted that the no-action letter “solely addresses an ATS trading digital asset securities under the circumstances set forth in this letter and does not otherwise address broker-dealer custody or control of digital asset securities.”", "pred_label": "__label__POS", "pred_score_pos": 0.7521567344665527}
{"content": "Emerson Network Power has released a Power Usage Effectiveness (PUE) calculator iPad app for its Liebert PCW cooling unit.\nThe free app allows data centre managers to keep a diary of their data centre’s PUE enabling more accurate decision-making about how and where energy savings can be made. Two different calculators are included in the app; the PUE calculator allows anyone to calculate the PUE of their data centre, while the basic running cost calculator highlights exactly how much money can be saved by installing more efficient equipment, such as the Liebert PCW.\nCooling systems typically account for 30-40% of energy consumption within a data centre*, so addressing their efficiency is a top priority for data centre managers. The app also includes an X-ray view into the Liebert PCW, giving users the opportunity to study the technical features of the solution and see how its technology can deliver energy savings for their data centre.\nEmerson has also announced an extension of the range’s capabilities, with a cooling capacity of up to 240 kW, as well as a new version of the Liebert PCW featuring a CW dual circuit, which offers cooling redundancy to customers who cannot install two units, without compromising efficiency.\n*Source Energy Logic 2.0 – 38% based on d/ctr of ~470sq.m", "pred_label": "__label__POS", "pred_score_pos": 0.7359566688537598}
{"content": "Biodegradable plastic: A false promise?\nIssued on:\nBiodegradable packaging is often pitched as the environmentally-friendly solution the world has been waiting for. However, so-called greener plastics don't necessarily break down as easily as marketers would have us believe. To make matters worse, biodegradable plastic can't be recycled. So if it doesn't readily disappear into nature and can't be reused, should we consider the \"biodegradable\" label a well-intentioned but misleading promise? The Down to Earth team investigates.", "pred_label": "__label__POS", "pred_score_pos": 0.9936951994895935}
{"content": "Background\nDr. Ayse P. Gurses is an associate professor of anesthesiology and critical care medicine at the Johns Hopkins University School of Medicine. She holds a joint appointment in Johns Hopkins’ Bloomberg School of Public Health’s Department of Health Policy and Management. Her areas of expertise include human factors engineering, patient safety, healthcare technology design, and implementation and usability evaluation.\nHer current research focuses on improving patient safety in the cardiac operating room, transitions of care/handoffs, care coordination, compliance of providers with evidence-based guidelines and nursing working conditions.\nDr. Gurses earned her Ph.D. in industrial engineering from the University of Wisconsin-Madison and completed her postdoctoral training at the University of Maryland-Baltimore. Before joining the Johns Hopkins University, she served as a faculty member at the University of Maryland-Baltimore and the University of Minnesota.\nShe is a member of Human Factors and Ergonomics Society, where she is the chair of the Health Care Technical Group. She also serves as the associate editor of\nIIE Transactions on Healthcare Systems Engineering. Her work has been recognized with numerous awards. Most recently, she was awarded with a Best Paper Award from Liberty Mutual Award for research examining patient safety in the cardiovascular operating room and an Early Career Investigator Award from the Federation of Associations in Behavioral and Brain Sciences (FABBS) Foundation.", "pred_label": "__label__POS", "pred_score_pos": 0.9606041312217712}
{"content": "Grades 5–9. Bring real-world, engineering problem-solving skills into your classroom. This set contains 288 K'NEX® parts. Hydro units require equipment such as pitchers, funnels, and bottles to hold, distribute, and measure water. The following models can be built and tested using this set:\nGrist Mill Hydro Car Hydroelectric Generator Sail Car Shuttle Ride Wind-Powered Water Lift Windmill\nThese models serve as an excellent way for students to examine the challenges of using renewable energy.\nThe teacher's guide provides a program of study that uses hands-on exploration in conjunction with an engaging inquiry-based approach to learning. Students are encouraged to build, investigate, and evaluate concepts, ideas, and designs. Both the teacher's guide and building instructions are aligned with the following Next Generation Science Standards:\n4-PS3-4. Apply scientific ideas to design, test, and refine a device that converts energy from one form to another. 4-ESS3-1. Obtain and combine information to describe that energy and fuels are derived from natural resources and their uses affect the environment.", "pred_label": "__label__POS", "pred_score_pos": 0.8826795816421509}
{"content": "We often think of post-traumatic stress disorder (PTSD) in association with combat veterans. While the condition does impact a large percentage of our military, PTSD can occur in anyone who has experienced trauma, whether physical or mental. Naturally, stress reactions following a traumatic event are expected, but if these stress reactions last longer than three months, cause great distress, or disrupt work/home life, it is time to seek help.Read More", "pred_label": "__label__POS", "pred_score_pos": 0.7412427663803101}
{"content": "Abstract Traditionally, athletes are selected for talent development programmes based on anthropometric factors, performance in competition, and motor-performance tests (Gullich & Cobley, 2017); psycho-social factors that influence athlete development have been largely ignored (Hardy et al., 2017). This research project seeks to develop the Athlete Development Formulation Survey (ADFS), a brief profiling tool gauging athletes' scores on psycho-social factors influencing elite performance. Following item generation, instrument construction, and establishing content validity, the present study reports on pilot work assessing the ADFS' concurrent validity. Two studies utilised a cross-sectional study design (Study 1; N =361, M hours training per week = 5.89, SD = 5.05; M years participating in sport = 7.35, SD = 6.47. Study 2; N = 66, Males = 30, Females = 36 (M hours training per week = 7.00, SD = 3.37; M years participating in sport = 7.34, SD = 2.84). Participants completed the ADFS alongside corresponding \"full\" measures with previously established psychometric properties. The ADFS is designed to assess 33 constructs. Across both studies, bi-variate correlations revealed significant and theoretically relevant associations between the ADFS constructs and their respective \"full\" measures. The present study adds support to the ADFS as a multi-faceted tool enabling identification of a combination of psycho-social factors that influence elite development. The ADFS has practical value within talent identification systems as it can be used to measure multiple factors without placing burden on athletes and coaches.", "pred_label": "__label__POS", "pred_score_pos": 0.991570770740509}
{"content": "The Westermann Morphospace method displays fundamental morphotypes and hypothesized life modes of measured ammonoid fossils in a ternary diagram. It quantitatively describes shell shape, without assumption of theoretical coiling laws, in a single, easy-to-read diagram. This allows direct comparison between data sets presented in Westermann Morphospace, making it an ideal tool to communicate morphology. By linking measured shells to hypothesized life modes, the diagram estimates ecospace occupation of the water column. Application of this new method is demonstrated with Mesozoic data sets from monographs. Temporal variation, intraspecies variation, and ontogenetic variation are considered. This method can address hypothetical ecospace occupation in collections with tight stratigraphic, lithologic, and abundance control, even when taxonomy is in dispute.\nYou have requested a machine translation of selected content from our databases. This functionality is provided solely for your convenience and is in no way intended to replace human translation. Neither BioOne nor the owners and publishers of the content make, and they explicitly disclaim, any express or implied representations or warranties of any kind, including, without limitation, representations and warranties as to the functionality of the translation feature or the accuracy or completeness of the translations.\nTranslations are not retained in our system. Your use of this feature and the translations is subject to all use restrictions contained in the Terms and Conditions of Use of the BioOne website.\nPaleobiology\nVol. 38 • No. 3\nSummer 2012", "pred_label": "__label__POS", "pred_score_pos": 0.6040301322937012}
{"content": "Sheffield, UK, October 2020 – Despite being legal in the UK for almost two years, access to medical cannabis and awareness among the public remains surprisingly low. So, we decided to put together a simple guide of how access to medical cannabis currently works. Legalising Medical Cannabis\nThe parents of Billy Caldwell and Alfie Dingley had tried a number of registered epilepsy medications with little success until they discovered the positive effects of cannabis-based medications. However, the legality of these drugs in the UK meant that they had to source medications from abroad.\nThe rescheduling of cannabis allowed for specialist clinicians in the UK to prescribe medical cannabis products. Following this decision, medical cannabis is now legal for the first time in almost 50 years.\nAccessing Medical Cannabis\nIn theory, patients should now be able to access medical cannabis products for a small number of conditions. These include treatment-resistant epilepsy, spasticity associated with multiple sclerosis, and chemotherapy-induced nausea and vomiting. However, NHS prescriptions for medical cannabis products – even for these conditions – remain critically low, if not non-existent.\nMedical cannabis clinics, however, have been opening around the nation with the aim of plugging the gaps in patient access. Sapphire Medical Clinics has launched a number of schemes and initiatives over the last couple of years in an effort to aid in the progression of the UK’s medical cannabis sector. These include the Sapphire Foundation which helps to remove financial barriers to patients and the UK Medical Cannabis Registry which collects real-world evidence on medical cannabis prescribing.\nProgressing Medical Cannabis Access in the UK\nThe data collected through our ongoing Canex poll support calls for increased education on medical cannabis – for both medical professionals and the public – in the UK. Despite numerous countries, including the UK, having now legalised medical cannabis, the potential mechanisms of cannabinoids and the endocannabinoid system is still not taught in medical curriculums.\nThis has led to a limited number of doctors having sufficient knowledge of medical cannabis and how it could potentially benefit a huge array of conditions. A number of initiatives are now aiming to address this problem, including the Sapphire Institute which provides an online training and up-to-date research on medical cannabis.\nMedical cannabis registries like the UK Medical Cannabis Registry and Drug Science’s Project Twenty21, aim to collect the evidence needed to support the progression of medical cannabis prescriptions in the UK.\nAbout Company:", "pred_label": "__label__POS", "pred_score_pos": 0.8818663358688354}
{"content": "Our knowledge and insight into the stock market enables us to craft an investment portfolio uniquely tailored to you. Through ongoing collaboration and monitoring, our team is able to discover new avenues for you to invest your wealth and accomplish your goals. In addition to managing your investments, we’ll educate you on the rationale behind each investment decision so you’re well-versed in the logic of our approach.\nWhen you work with us, we will: Identify Your Short- and Long-Term Objectives As these objectives change, we’ll strategically adjust our approach according to the current state of the market so you continue to generate returns. Determine Your Optimal Risk Tolerance Through a series of questions, we’ll pinpoint the exact amount of risk needed for you to achieve your goals and remain confident in our services. Follow a Timeline That’s Right For You After outlining your objectives, we’ll design a strategy that aligns with your optimal timeline for achieving your returns.", "pred_label": "__label__POS", "pred_score_pos": 0.7170030474662781}
{"content": "“Education is the kindling of a flame, not the filling of a vessel.”\n-Socrates\nFor us, it’s not just about helping students learn effectively. It’s about helping students love learning — to see it as something they can do inside the classroom and out, no matter the challenges they face. That’s why we focus on addressing the core challenges associated with dyslexia, while, at the same time, helping students uncover and develop their strengths.\nDyslexia is a common learning disorder, affecting 20% of the general population and 80-90% of individuals with learning disabilities. Students with dyslexia have a hard time identifying the sounds associated with the letters they see. While they may recognize the name of the letter, they may not be able to identify the sound the letter makes in a word. Remediation works by teaching students how to identify the sounds associated with each letter, and how to blend them into words.", "pred_label": "__label__POS", "pred_score_pos": 0.8935585021972656}
{"content": "Abstract\nA fundamental investigation of the influence of novel phosphonium bromide salts within the polymer main chain (23.75 mol %) of polyurethanes was conducted to elucidate the effect of ionic associations on hard segment hydrogen bonding. A novel poly(tetramethylene oxide) (PTMO)-based polyurethane containing a phosphonium diol chain extender was prepared using a conventional prepolymer method. In addition, a polyurethane containing a 1,4-butanediol chain extender was synthesized for comparison with the thermomechanical and morphological properties of the phosphonium ion-containing analog. Moreover, the unprecedented comparison of morphological development in the presence of cationic sites is described herein. Differential scanning calorimetry (DSC) revealed that phosphonium polyurethane was more crystalline compared to the noncharged analog, and it was presumed that enhanced hydrogen bonding in the noncharged polyurethane restricted polymer mobility and reduced PTMO crystallinity. Moreover. FT-IR spectroscopy demonstrated that hydrogen-bonding interactions were significantly reduced in the presence of phosphonium cations. These results correlated well with tensile properties, i.e., the noncharged polyurethane offered superior tensile strength compared to phosphonium polyurethane. X-ray scattering indicated that both polyurethanes were amorphous at room temperature and exhibited hard segment microphase separation. Upon stretching, the interparticle scattering between the microphase-separated domains aligned preferentially along the stretching direction. Scanning transmission electron microscopy (STEM) and energy-dispersive X-ray spectroscopy (EDS) in the STEM indicated that the charged polyurethane exhibited ionic aggregates that were rich in P and Br.\nASJC Scopus subject areas Organic Chemistry Materials Chemistry Polymers and Plastics Inorganic Chemistry", "pred_label": "__label__POS", "pred_score_pos": 0.796983003616333}
{"content": "Let’s say a U.S. law enforcement agency obtains a warrant against a criminal suspect. As a part of the investigation, the agency requests that an online service provider hand over the suspect’s emails, which in this case are located on a server abroad. Does the provider have to comply? Not according to what is colloquially known as the “\nMicrosoft-Ireland” decision from last year. In Microsoft, the Second Circuit held the Stored Communications Act (SCA) could not be used to compel Microsoft to disclose a user’s email content stored extraterritorially—in that case, exclusively on an Irish server. Instead, U.S. law enforcement must use the now-cumbersome and slow Mutual Legal Assistance Treaty (MLAT) process to request data through their international counterparts. Given the limits of the existing SCA, the Court called for Congress the change the law to address how U.S. companies hold data overseas.\nAt a May 24 hearing, members of Senate Judiciary Committee Subcommittee on Crime and Terrorism came to a consensus that the system for cross-border data requests is broken. They agreed with witnesses that technology companies are situated amid conflicting state interests in two related scenarios: 1) when U.S. providers receive requests from U.S. law enforcement for data possibly stored outside the U.S.—akin to\nMicrosoft-Ireland, and 2) when U.S. providers receive requests from foreign law enforcement for data those providers control. In the latter scenario, the SCA prevents providers from disclosing email to foreign law enforcement without a warrant issued pursuant to the MLAT process.\nUnfortunately, as Chairman Lindsey Graham highlighted, the MLAT process is antiquated and no longer effective in a fast-paced digital era, echoing concerns from law enforcement agencies around the world. The committee resolved to address the adverse impact of the Second Circuit’s 2016 decision in a bipartisan manner that would reflect modern technological considerations and the privacy, security, and law enforcement equities at stake.\nRepresenting the U.S. law enforcement perspective was Brad Wiegmann, Deputy Assistant Attorney General of the Department of Justice’s (DOJ) National Security Division. He testified that DOJ has identified over 100 incidents of impeded investigations due to tech companies’ unwillingness to share a user’s electronic data following the\nMicrosoft-Ireland decision, and urged Congress to find a solution to that side of law enforcement’s cross-border conundrum.\nTo address the second scenario described above, Wiegmann renewed DOJ’s commitment to a proposed bilateral agreement between the U.S. and United Kingdom. First announced last year, the U.S.-UK agreement would permit UK law enforcement to directly request communications content from U.S. providers pursuant to their own form of lawful process. DOJ’s hope is that this agreement would be the first of many such bilateral arrangements between the U.S. and like-minded nations with similar law enforcement needs. Weigmann noted that in order for such bilateral agreements to take effect, Congress would need to pass a legislative framework that both amends the Stored Communications Act’s disclosure provisions to allow direct responses by U.S. providers to requests from foreign law enforcement, and sets human rights, rule of law, and legal process standards for the community of nations that might be eligible for such agreements with the U.S. Weigmann indicated that DOJ would be issuing a new draft legislative proposal, similar to one it transmitted to Congress last year, in the near future. Importantly, Weigmann noted that DOJ’s proposal would not factor into existing debates over surveillance or encryption, and would help stem the tide of increasing data localization efforts abroad.\nPaddy McGuinness, the UK’s Deputy National Security Advisor, also testified, providing the perspective of foreign law enforcement agencies. McGuinness noted that increasing amounts of criminals’ communications take place over services provided by U.S. technology companies. McGuinness also took time to describe the changes made to the UK’s investigatory powers regime under the recently-passed Investigatory Powers Act, which includes expansions to UK law enforcement’s ability to request data from providers, along with substantive changes to the procedures through which such requests are made.\nSenator Orrin Hatch, long involved in discussions of cross-border law enforcement issues, acknowledged that law enforcement’s demand for data inherently conflicts with privacy, and again put forth his proposed solution to the\nMicrosoft prong of the problem: a revised version of the International Communications Privacy Act (ICPA), a bill he first introduced last year. ICPA would permit U.S. law enforcement to obtain the extraterritorially stored communications of U.S. persons or persons reasonably believed to be located in the U.S. pursuant to a probable cause-based warrant. In Senator Hatch’s view, DOJ’s proposed legislation does not fully resolve the conflict of laws dilemma faced by U.S.providers—including, for example, a pending Brazilian law that prohibits technology companies from disclosing Brazilian citizens’ data—whereas ICPA might take steps in that direction.\nBrad Smith, Microsoft’s Chief Legal Officer, testified from the perspective of the technology industry and as a representative of the company that had most acutely faced the cross-border problem in court. He testified that a complete reversal of\nMicrosoft would “literally take us back to a law that was passed when Mark Zuckerberg was two years old,” and “simply wouldn’t work” because it puts technology companies in the conflict of law dilemma highlighted by Senator Hatch. Smith also mentioned that no action on the issue leaves companies facing astronomical fines in some jurisdictions (e.g. under the European Union’s looming General Data Protection Regulation), and puts American jobs at risk. In Smith’s opinion, the DOJ’s legislative proposal opens the door solving part of the problem while balancing privacy and security, but more work must be done.\nJennifer Daskal, Associate Professor at American University Washington College of Law, testified that a clean reversal of the Second Circuit’s decision in\nMicrosoft would be problematic and ignore foreign states’ comity interests. Daskal advocated that courts engage in a careful examination of the location of the crime, suspect, and its victim; location of data alone to determine jurisdiction is problematic because data is constantly moving. Daskal explained that a user’s location or nationality is more reliable and solves the issue of notice asymmetry since a user has expectations or presumptions about the law based on where he or she is located. This is similar to the framework Senator Hatch is preparing in the revised version of his proposed ICPA. We can expect to see a revised ICPA reintroduced by Senator Hatch: “ICPA is one of my top priorities,” he remarked, “and I plan to push very hard for it once it’s reintroduced.”\nNext week, the House Judiciary Committee will also be holding a hearing on law enforcement access to data stored abroad. Chairman Bob Goodlatte has stated reforming 1986’s Electronic Communications Privacy Act, which contains the SCA and its disclosure prohibitions, as a top priority. While speaking before the Federalist Society at the National Press Club in February, he described the law as, “outdated and contains insufficient privacy protections,” and reform is necessary to, “better protect constitutional rights without impeding law enforcement’s efforts to protect public safety.”", "pred_label": "__label__POS", "pred_score_pos": 0.5700398683547974}
{"content": "Rasmus Rosenberg Larsen\nMind & Language. 2020; 1– 17.\nAbstract\nPsychopathy has been theorized as a disorder of emotion, which impairs moral judgments. However, these theories are increasingly being abandoned as empirical studies show that psychopaths seem to make proper moral judgments. In this contribution, these findings are reassessed, and it is argued that prevalent emotion‐theories of psychopathy appear to operate with the unjustified assumption that psychopaths have no emotions, which leads to the hypothesis that psychopaths are completely unable to make moral judgments. An alternative and novel explanation is proposed, theorizing psychopathy as a degree‐specific emotional deficiency, which causes degree‐specific differences in moral judgments.\nFrom the Conclusion Section\nMotivated by a suite of ostensibly undermining empirical studies, this paper sought to defend and qualify emotion-theories of psychopathy by explicating in detail the philosophical and psychological commitments these theories appear to be implicitly endorsing, namely, a (constructivist) sentimentalist framework. This explication demonstrated, above all, that psychopathy studies appear to operate with an inconsistent set of hypotheses when trying to capture the differences between diagnosed psychopaths and controls in terms of their moral judgments and values. This led to a consideration of alternative research designs particularly aimed at capturing the potential moral psychological differences that follows from having diminished emotional dispositions, namely, degree-specific differences related to the two-dimensional value spectrum, as opposed to differences related to answers on moral categorical issues.", "pred_label": "__label__POS", "pred_score_pos": 0.5366296172142029}
{"content": "Member Benefits\nFrom shipping to staffing, the Chamber and its partners have the tools to save your business money and the solutions to help you run it more efficiently. Join the U.S. Chamber of Commerce today to start saving.\nIn July of this year, the Securities and Exchange Commission (SEC) finalized its Proxy Advisor rule, which marked an important step in making the corporate governance landscape more hospitable for public companies. For decades, the U.S. has seen a decline in the number of public companies, which has had an adverse impact on growth, innovation, and job creation. The U.S. Chamber of Commerce has been committed to reversing this trend by fighting for responsible corporate governance policies that focus on economic return and benefit the long-term position of shareholders.\nThe SEC’s Proxy Advisor rule is a key component of reversing that trend. For too long, proxy advisory firms have been allowed to frustrate public companies with factual mistakes, methodological weakness in devising recommendations, conflicts of interest in those recommendations, and a lack of transparency in assumptions, sources, and analyses. The SEC’s Proxy Advisor rule takes significant steps to ameliorate these issues and the Chamber’s amicus filing emphasizes the importance of the rule to the business community and investors.\nOn Friday, November 6, the U.S. Chamber moved to defend the SEC’s rule by filing an amicus brief in Institutional Shareholder Services, Inc. (ISS) v. SEC. In the lawsuit, ISS challenges the SEC’s Proxy Advisor rule, which applies the proxy solicitation rules to the provision of proxy advice. The Chamber’s amicus filing supports the SEC’s rule, arguing that the SEC acted within the scope of its statutory powers and that the rule is reasonably tailored to address significant concerns about the provision of proxy voting advice. The U.S. Chamber’s amicus efforts were led by the Chamber’s Center for Capital Markets Competitiveness (CCMC) and the U.S. Chamber Litigation Center.\nIn conjunction with the amicus brief, CCMC also published a white paper, Examining the SEC’s Proxy Advisor Rule, that provides an overview of the SEC’s rulemaking process, specifically examining the SEC’s process through the lens of the Administrative Procedure Act (APA). The white paper, which is cited in the Chamber’s amicus brief, concludes that the SEC has statutory authority to promulgate the rule and that the final rule reflects reasoned decision-making as required by the APA.\nCCMC’s report carefully weighs the criticisms of proxy advisory firms and the SEC’s efforts to address those criticisms through its proposed rule in November 2019. The report discusses the response to that proposal and details the modifications the SEC made to its final rule after carefully considering the comments to its proposed rule. The white paper concludes that the SEC convincingly demonstrates the need for regulation given the potential conflicts of interest and poor-quality governance advice in the proxy advisory industry. It further reasons that the SEC’s thoughtful changes between proposal and finalization of the rule further support the reasonableness of the rule.\nThe SEC’s final Proxy Advisor rule is a step in the right direction to address deficiencies in the proxy advisory system. The rule brings greater transparency, better oversight and clarity around conflicts of interest, and heightened investor protection in the proxy voting process. CCMC supports added transparency and accountability in the provision of proxy advice and will therefore continue to advocate for and defend reforms like the SEC’s Proxy Advisor rule.", "pred_label": "__label__POS", "pred_score_pos": 0.5463098287582397}
{"content": "Peak periods and shopping days are big business.\nShoppers wind down their spending, wait for the best prices and spend in incredible volumes.\nThere are direct consequences for marketplace sellers. Longer slow periods and more intense peaks. Preparation has become crucial for success.\nThis guide provides you with a helpful checklist starting six months out from your own peak period, helping you to maximize profits during your specific sales window.\nFill in the form below to get your copy.", "pred_label": "__label__POS", "pred_score_pos": 0.9738410711288452}
{"content": "Most of a railway system operates outdoors with specific and often demanding maintenance actions required to achieve dependability and safety, ensuring both availability and optimal life cycle costs. The availability of a system depends on reliability and robustness, maintainability and supportability.\nAt the moment, we are supporting JVTC by acting as project coordinator and process leader in ePilot119. This is a pilot project in collaboration with the Swedish Transport Administration, railway operators, maintenance contractors for vehicles and infrastructure, suppliers and consultants, with the objective of implementing research and innovations", "pred_label": "__label__POS", "pred_score_pos": 0.9994162321090698}
{"content": "”And He came and found them sleeping, and said to Peter, ‘Simon, are you asleep? Could you not keep watch for one hour? Keep watching and praying that you may not come into temptation; the spirit is willing, but the flesh is weak.’” – Mark 14:37-38\nAs Jesus agonized through one of the hardest moments in his life, his closest friends and followers snored. It had to be difficult for Jesus. He knew, in the greatest of detail, all that awaited him over the next 24 hours. In his mind, he could see the betrayal of Judas, the thirty pieces of silver, the crowds shouting ‘Crucify Him!”, the crown of thorns that would tear into his scalp and the awful cross that would end his earthly life. And though he had tried to tell his disciples about what was coming, they hadn’t believed him. In fact, Peter had gone so far as to rebuke him for his talk of sacrifice. Before he went to pray, he commanded them, “Remain here and keep watch.” He was asking them to go before God and seek the strength and sustaining power that they’d need for the upcoming trial. Unfortunately, they didn’t comprehend the gravity of the situation; so they slept.\nHow often do we miss the importance or the seriousness of what God is calling us to? Each of us has a calling on our lives. It doesn’t matter whether you consider yourself a missionary or not. It doesn’t matter whether you think you’re in ‘full-time’ or ‘part-time’ or ‘no-time’ ministry. As a Christian, we all have a calling on our lives. We all face trials of faith and character. We all face times when God calls us to witness about Him and His saving power. We all have a daily call; a daily mission, if you will. And if we do not “keep watching and praying,” there’s a good chance we’ll fail Him.\nJesus tells Peter and the others, “the spirit is willing, but the flesh is weak.” He recognized that people’s spirits often have the desire to do the right thing but many fall short of that desire. Why is that? It’s simple. They aren’t relying wholly on God by constantly seeking his power and by feasting on the Bread of Life. If we’re going to endure every trial and pass every test, we need to be watching and praying to the only one who is able to “keep us from stumbling” (Jude 24). Don’t let Christ find you sleeping today, be alert, watch and pray. If you do, though trials come, you needn’t fear, for “God shall supply all your need according to his riches in glory by Christ Jesus” (Philippians 4:19).", "pred_label": "__label__POS", "pred_score_pos": 0.584294319152832}
{"content": "Human Immunodeficiency Virus (HIV) researchers at\nThe University of Texas Medical School at Houstonbelieve they have uncovered the Achilles heel in the armor of the virus that continues to kill millions. The weak spot is hidden in the HIVenvelope protein gp120. This protein is essential for HIVattachment to host cells, which initiate infection and eventually lead to Acquired Immunodeficiency Syndromeor AIDS. Normallythe body's immune defenses can ward off viruses by making proteins called antibodies that bind the virus. However, HIVis a constantly changing and mutating virus, and the antibodies produced after infection do not control disease progression to AIDS. For the same reason, no HIVpreventative vaccine that stimulates production of protective antibodies is available. READ MORE", "pred_label": "__label__POS", "pred_score_pos": 0.62037193775177}
{"content": "The perceived trend of millennials prioritising lifestyle experiences (such as buying smashed avocado on toast), over home ownership aspirations prompted a deeper look into this claim.\nTo better understand how millennials (specifically tertiary students in Brisbane) view home ownership, three survey questions were posed:\nDo tertiary students aspire to home ownership?\nA firm yes! The results showed 77.0% consider home ownership ‘extremely’ or ‘very important’.\nWhat type of housing would tertiary students prefer?\nThey would prefer a stand-alone house with 3 bedrooms, 2 bathrooms, 1 lounge room, and enough room for 2 cars. It was also found they would like to live within a 6-10km radius of Brisbane’s CBD, and be close to transport modalities and public amenities.\n$400K - $600K was the price range for a home that most of the tertiary students were shown to favour (41.0%). However, the continued rise of property prices ahead of wage growth has made the traditional notion of home ownership seem unattainable to them.\nWhat are the barriers to home ownership for tertiary students?\n-Price - 27.5% identified price as the greatest barrier to entry in purchasing their first home.\n-Interest rate increases – this was distinguished as a significant barrier to entry, as interest rate increases are unpredictable and can have a significant impact on first home buyers.\n-Lack of property market knowledge and experience – many tertiary students simply don’t have the property market experience or knowledge to make them confident enough to purchase a home.\nAlthough home ownership was identified as ‘extremely’ or ‘very important’ to tertiary students, it was revealed to be a future aspiration by many surveyed (5+ years into the future). Participants also indicated that while home ownership is currently desirable, their preferences could change over time.", "pred_label": "__label__POS", "pred_score_pos": 0.6546399593353271}
{"content": "In Canada, drunk drivers can be charged with one or both of the following offenses: impaired driving and driving over 80, which means having a blood alcohol level over 80 mg of alcohol per 100 ml of blood. In nearly all cases, this figure is written as 0.08 percent BAC. Both convictions carry substantial penalties that include fines, jail time and a driver's license suspension.\nPenalties faced for a DUI offense depend on several factors, including:\nDriver's BAC. Driver's status as a novice driver, commercial driver or fully licensed driver. Driver's previous DUI record. Driver's home province. Whether an injury or death occurred because of the driver's actions.\nImpaired driving does not only refer to drunk driving. It can also refer to driving while under the influence of any substance, such as cannabis or a prescription drug.\nIn Canada, it is possible for a driver to face administrative and criminal penalties when his BAC is determined to be in the \"warn\" range, 0.05 to 0.08 percent BAC.\nDUI Is a Criminal Conviction\nA DUI is a federal offense in Canada and will result in a criminal conviction on your record. The Crown of Canada determines whether prosecution is pursued as an indictment (equivalent to a felony in the United States) or as a summary conviction (equivalent to a misdemeanor in the U.S.). Most DUI charges in Canada are prosecuted as summary convictions.\nBeing convicted of impaired driving leads to many penalties that can include:\nA mandatory ignition interlock device on the driver's vehicle. Mandatory completion of a drug rehabilitation program. Medical evaluation to determine whether the driver is fit to drive again. Fines Assessed for DUI\nA driver faces a fine of $1,000 or more for an impaired driving conviction, refusing to provide a BAC test sample or driving with a BAC of 0.08 percent or higher. Subsequent offenses in these categories result in higher fines. For driving while prohibited from doing so or driving after being federally convicted of impaired driving, a driver faces a fine of up to $2,000.\nA driver facing her first charge of driving while in the warn range faces a fine of $250. Subsequent charges result in higher fines and additional fees, like a $250 driver's license reinstatement fee.\nRead More: Is a DUI a Felony? Jail Time Is Possible\nOn July 2, 2008, Canada’s minimum punishment for DUI offenses was amended. A first offense now carries a minimum fine of $1,000 and second offenses within a 10-year period are punishable by a minimum 30-day jail term. Each subsequent conviction will result in jail time of at least 120 days. Summary convictions carry a maximum sentence of 18 months.\nLoss of License\nWhen a Canadian driver is convicted of impaired driving, he faces two distinct driver's license suspensions: a criminal suspension, which is imposed by the federal government, and an administrative suspension, which is imposed by the government of the province where the driver lives. A driver faces an administrative suspension regardless of the outcome of his criminal case. The length of this suspension depends on the driver's province.\nAs of 2019, law enforcement can also suspend drivers' licenses immediately (while stopped by police at the side of the road) upon determining that the driver was under the influence. For a first-time offense, the driver faces a three-day suspension and a $250 fine. The suspension length, fine amount and whether the driver faces additional penalties depend on her age, license type and previous DUI record. If the driver is found guilty of impaired driving in court, she can face additional criminal penalties.\nAdditional Fines for Driving While Prohibited\nOnce a driver's license is suspended, the driver is prohibited from driving. This is true even if he has not yet gone to court to fight the charge. Penalties for driving with a suspended license prior to a DUI hearing are:\nFine of $500 to $2,000 for a first offense. Fine of $500 to $2,000, plus 14 days or longer in jail for a second offense, and a one-year extension to the suspension.\nAfter the driver has been convicted, he faces these same penalties for driving while his license is suspended.\nTravel Restrictions After Conviction\nThose convicted of a DUI or DWI in the U.S. within the past 10 years may be denied entry into Canada. Since DUI (having a blood alcohol level above 0.08 percent in the United States) is the equivalent of a serious criminal offense, only those deemed rehabilitated can enter the country. This involves applying for an individual criminal rehabilitation by submitting an application along with proof that you have served your sentence, paid all associated fines and have three letters of reference.\nTips\nIn Canada, it is illegal to drive when your BAC is 0.08 percent or higher.\nReferences\nWriter Bio\nLindsay Kramer is a freelance writer and editor who has been working in the legal niche since 2012. Her primary focus areas within this niche are family law and personal injury law. Lindsay works closely with a few legal marketing agencies, providing blog posts, website content and marketing materials to law firms across the United States.", "pred_label": "__label__POS", "pred_score_pos": 0.5699267387390137}
{"content": "Myocardial infarction (MI) leads to a severe loss of cardiomyocytes, which in mammals are replaced by scar tissue. Epicardial derived cells (EPDCs) have been reported to differentiate into cardiomyocytes during development, and proposed to have cardiomyogenic potential in the adult heart. However, mouse MI models reveal little if any contribution of EPDCs to myocardium. In contrast to adult mammals, teleosts possess a high myocardial regenerative capacity. To test if this advantage relates to the properties of their epicardium, we studied the fate of EPDCs in cryoinjured zebrafish hearts. To avoid the limitations of genetic labelling, which might trace only a subpopulation of EPDCs, we used cell transplantation to track all EPDCs during regeneration. EPDCs migrated to the injured myocardium, where they differentiated into myofibroblasts and perivascular fibroblasts. However, we did not detect any differentiation of EPDCs nor any other non-cardiomyocyte population into cardiomyocytes, even in a context of impaired cardiomyocyte proliferation. Our results support a model in which the epicardium promotes myocardial regeneration by forming a cellular scaffold, and suggests that it might induce cardiomyocyte proliferation and contribute to neoangiogenesis in a paracrine manner.\nCopyright © 2012 Elsevier Inc. All rights reserved.", "pred_label": "__label__POS", "pred_score_pos": 0.8935164213180542}
{"content": "Handbook of Nanophysics: Nanotubes and Nanowires\nAuthor:\nKlaus D Sattler\nFormat:\nPaperback\nPages:\n784\nISBN:\n9780367383619\nPublisher:\nCRC Press\nRelease Date:\nOctober 23, 2019\nIntensive research on fullerenes, nanoparticles, and quantum dots in the 1990s led to interest in nanotubes and nanowires in subsequent years. Handbook of Nanophysics: Nanotubes and Nanowires focuses on the fundamental physics and latest applications of these important nanoscale materials and structures. Each peer-reviewed chapter contains a broad-based introduction and enhances understanding of the state-of-the-art scientific content through fundamental equations and illustrations, some in color.\nThis volume first covers key aspects of carbon nanotubes, including quantum and electron transport, isotope engineering, and fluid flow, before exploring inorganic nanotubes, such as spinel oxide nanotubes, magnetic nanotubes, and self-assembled peptide nanostructures. It then focuses on germanium, gallium nitride, gold, polymer, and organic nanowires and their properties. The book also discusses nanowire arrays, nanorods, atomic wires, monatomic chains, ultrathin gold nanowires, and several nanorings, including superconducting, ferromagnetic, and quantum dot nanorings.\nNanophysics brings together multiple disciplines to determine the structural, electronic, optical, and thermal behavior of nanomaterials; electrical and thermal conductivity; the forces between nanoscale objects; and the transition between classical and quantum behavior. Facilitating communication across many disciplines, this landmark publication encourages scientists with disparate interests to collaborate on interdisciplinary projects and incorporate the theory and methodology of other areas into their work.", "pred_label": "__label__POS", "pred_score_pos": 0.5350438952445984}
{"content": "Team alignment\nAligned, committed people achieve higher results together. Working with others can be challenging. Learning how to align with others can create a better understanding of the self and the team, and helps create a culture of performance. We use our expertise to challenge strategy, alignment and communication within teams and organisations. It is a top down focus on how to drive efficient, engaged and profitable outcomes for the business.\nOrganisations always look for ways to realise strategy, align their people and build clear communication policies within their teams and, outwardly towards customers. After all customers are central to business success. We help senior leaders find a clear strategy and communicate it within their teams. Alignment is the key to return on investment activities.\nWe also offer behaviour profiling, DISC and motivators and 360 assessments. These tools allow us to understand how your team works and how individuals contribute to the team and business. They measure how people prefer to behave, and assess workplace motivators and why people do what they do. They also help align expectations and behaviours in a team by gaining an insight into team dynamics and strengths.\nRange\nAssignments vary depending on client requirements. Programs can run from just a single day to many daily sessions over a few months. To support the coaching activities, we use behaviour profiling and 360 degree assessments.\nTarget audience\nTeam alignment programs are perfect for teams that are underperforming and are struggling to achieve results together. As programs help build trust and alignment, all staff will benefit from these sessions.\nOutcomes\nHelp your team value alignment and build strategies to challenge their thinking and drive results. Our sessions are interactive forums that create personal buy-in from the whole team. They build trust and reduce conflict, which then improves business outcomes.\nDon’t endure lack of alignment, poor communication and the negative consequences which result in low productivity and unhappy people. Let us assess your requirements and propose a solution.\nContact us to craft your solution", "pred_label": "__label__POS", "pred_score_pos": 0.8075540661811829}
{"content": "The celebrations are being held in conjunction with the Coordinating Groups of Pesticides Control Boards of the Caribbean (CGPC). The Agriculture Departments in both St. Kitts and Nevis will host a week of activities designed to emphasize the safe use of pesticides in the Federation, while highlighting the need for safe pesticide management.\nActivities scheduled for Pesticides Awareness Week include Tag Day on September 27\nth, Pesticides Awareness Day and a Pesticide and Calibration Workshop. Pest control operators are being encouraged to register at the Department of Agriculture on Tuesday, 27 th September, 2011 from 10am to 12pm.\nPesticides Awareness Week offers the route through which the Department of Agriculture notifies the general public and producers at large of the need for sustainable agriculture by utilizing less pesticides and increasing the quality of human health and the environment for generations to come.\nIt is the aim of both Departments of Agriculture to inform the residents about the benefits and risks associated with pesticide use, as well as their role in ensuring the safe and effective use of these chemicals.", "pred_label": "__label__POS", "pred_score_pos": 0.5661435127258301}
{"content": "7\nUrinary exosomal microRNAs as potential non-invasive biomarkers in breast cancer detection Berner K. 1, Hirschfeld M. 1,2,3, Rücker G. 2,4, Weiß D. 1,2, Ritter A. 1,2, Jäger M. 1,2, Juhasz-Böss I. 1,2, Erbes T. 1,2\n1University of Freiburg, Medical Center, Department of Obstetrics and Gynecology, Freiburg, Deutschland, 2University of Freiburg, Faculty of Medicine, Freiburg, Deutschland, 3Georg-August-University Goettingen, Institute of Veterinary Medicine, Goettingen, Deutschland, 4University of Freiburg, Medical Center, Institute of Medical Biometry and Statistics, Freiburg, Deutschland\nBreast cancer (BC) is the most frequent malignant disease in women worldwide and the leading cause of cancer associated death as well. As especially advanced stages are challenging for the healthcare system, early BC detection is crucial striving for improved overall outcome and disease management. Established screening procedures show limited success in the early diagnosis of the disease and inherit several limitations. Aiming at a faster, easier and non-invasive BC screening, liquid biopsy biomarkers bear great potential to complete the current state-of-the-art diagnostics. This study explores the diagnostic potential of BC specific urinary microRNAs as a potential non-invasive BC screening method. Based on a case-control-study (69 BC patients vs. 40 healthy controls), expression level quantification and subsequent biostatistical computation of thirteen urine-derived microRNAs was performed to evaluate their diagnostic relevance in BC. Multilateral statistical assessment determined and repeatedly confirmed a specific panel of four urinary microRNAs (miR-424/miR-423/mir-660/let7-i) as highly specific combinatory biomarker tool. Herewith, it is possible to discriminate BC patients from healthy controls with 98.6 % sensitivity and 100 % specificity. Smaller feasibility studies have proven this method as highly potent already years ago. The given study finally provides large scale observations, sufficient statistic analysis, more refined methods and highly satisfying sensitivity and specificity. Therefore, it serves the implementation of urinary BC detection in the routine screening and offers a promising non-invasive alternative.", "pred_label": "__label__POS", "pred_score_pos": 0.5959053039550781}
{"content": "We believe in long-term growth in Eastern Europe and Central Asia. This boundless region, located in between Europe and Asia, will benefit from China’s plans to re-establish the New Silk Road. Just like in medieval times, this was a trade corridor connecting the continents.\nNatural resource-rich CIS countries are ripe for increased global investment. Russia has significantly improved ease of doing business, which is assessed by the World Bank on an annual basis. In terms of investment climate, Kazakhstan and Belarus are catching up to the EU standards.\nLow oil prices have led to currency devaluation but improved competitiveness in export-oriented processing industries. Countries like Kazakhstan and Russia are extremely rich in raw materials, but companies tended to export the crude. Now, oil and gas are increasingly being processed and refined to finished products, providing value-adding for businesses and the economy as a whole.\nAs Eurasia experiences a new influx of industrialization, governments are actively supporting localization through policy-making regulations.\nCREON Group will play an instrumental part in these investing trends. The lucrative project opportunities are endless in crude to products. CREON Group has all the knowledge and the expertise for projects and initiatives across the region.", "pred_label": "__label__POS", "pred_score_pos": 0.5793224573135376}
{"content": "This year has been a painful one for small businesses. The coronavirus pandemic has kept economies closed, customers at home, and spending to a minimum. Economists predict that COVID-19 will cause the greatest recession the world has seen in nearly a century.\nA Saudi man walks at the Tadawul Saudi Stock Exchange, in Riyadh, Saudi Arabia. (File photo: AP)\nBeyond the money\nA woman shops for laundry detergent at a supermarket in Saudi Arabia's capital Riyadh on October 18, 2020. (AFP)\nFund of funds rising\nSaudi women work at a dates packaging factory in Al-Ahsa, Saudi Arabia. (Reuters)", "pred_label": "__label__POS", "pred_score_pos": 0.8772818446159363}
{"content": "A practical guidance for assessments of sedentary behavior at work: A PEROSH initiative\nForskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift\nAbstract\nAbstract Sedentary behavior is defined as sitting or lying with low energy expenditure. Humans in industrialized societies spend an increasing amount of time in sedentary behaviors every day. This has been associated with detrimental health outcomes. Despite a growing interest in the health effects of sedentary behavior at work, associations remain unclear, plausibly due to poor and diverse methods for assessing sedentary behavior. Thus, good practice guidance for researchers and practitioners on how to assess occupational sedentary behavior are needed. The aim of this paper is to provide a practical guidance for practitioners and researchers on how to assess occupational sedentary behavior. Ambulatory systems for use in field applications (wearables) are a promising approach for sedentary behavior assessment. Many different small-size consumer wearables, with long battery life and high data storage capacity are commercially available today. However, no stand-alone commercial system is able to assess sedentary behavior in accordance with its definition. The present paper offers decision support for practitioners and researchers in selecting wearables and data collection strategies for their purpose of study on sedentary behavior. Valid and reliable assessment of occupational sedentary behavior is currently not easy. Several aspects need to be considered in the decision process on how to assess sedentary behavior. There is a need for development of a cheap and easily useable wearable for assessment of occupational sedentary behavior by researchers and practitioners.\nDetaljer\nFörfattare Enheter & grupper Externa organisationer Forskningsområden Ämnesklassifikation (UKÄ) – OBLIGATORISK Nyckelord\nOriginalspråk engelska Sidor (från-till) 41-52 Antal sidor 12 Tidskrift Applied Ergonomics Volym 63 Status Published - 2017 sep Publikationskategori Forskning Peer review utförd Ja", "pred_label": "__label__POS", "pred_score_pos": 0.6126381158828735}
{"content": "Abstract\nIndustrial wastewater treatment plants must operate properly during the transient-state conditions often found in the industrial production. This study presents the performance of simultaneous partial nitritation and o-cresol biodegradation in a continuous aerobic granular reactor under sequentially alternating pollutant (SAP) scenarios. Three SAP scenarios were imposed during the operation of the granular reactor. In each one, a secondary recalcitrant compound (either p-nitrophenol (PNP), phenol or 2-chlorophenol (2CP)) were added for a short period of time to the regular influent containing only ammonium and o-cresol. Partial nitritation and o-cresol biodegradation were not inhibited by the presence of PNP or phenol and both compounds were fully biodegraded. On the contrary, the presence of 2CP strongly inhibited both processes within 2. days. However, the reactor was recovered in a few days. These findings demonstrate that treatment of complex industrial wastewaters with variable influent composition is feasible in a continuous aerobic granular reactor. © 2014 Elsevier Ltd.\nKeywords 2-Chlorophenol Aerobic granules P-Nitrophenol Partial nitrification Phenol", "pred_label": "__label__POS", "pred_score_pos": 0.9940495491027832}
{"content": "Amazon charged Amelia San Filippo, a sophomore at the University of Delaware, a $3,800 fee for failing to return a rented textbook on time. Apparently, San Filippo missed the fine print in her rental agreement. If she didn't return the book by June 4 she would be charged to purchase the book.\nWhat is the title of this valuable tome?\nCultural Anthropology: A Toolkit for a Global Age, which can be bought online for $150!\nAmelia returned the book and her father got the charge reversed after a nine-hour phone call to Amazon's customer service. Amazon issued a statement to a local television news program saying:\nThis was an isolated error that we quickly resolved directly with the customer and have issued a refund. We've apologized to the customer and are taking additional actions to ensure this situation does not happen again.In my mind, this message is corporatespeak for \"Oops! We got caught.\"\nThis kind of nonsense happens all the time in our brave new world where universities and their corporate outsourcers treat college students like cash cows.\nI myself had a similar encounter with Louisiana State University a few years ago. My wife and I arrived to do volunteer work at the Catholic student center located on the LSU campus. We came in separate cars and parked in a lot marked \"Church Parking.\" There was a gate to the parking lot, but the gate was open.\nAt the end of our volunteer activity, we found parking tickets on our cars informing us that we were each being charged $330 for unauthorized parking: $660 in total. Must be some mistake.\nI walked to the LSU Visitor Center, where a parking employee immediately knocked off two $300 fees. But she would not clear two fees for $30. To no avail, I explained that we were on church business and that we parked in a lot designated for church parking. If I wanted to challenge the tickets, I was told, I could file an administrative appeal.\nFor about a year, LSU sent my wife and I separate monthly bills of $30. Then we got letters saying the matter was being turned over to the District Attorney for collection. At that point, I wrote checks totally $60.\nMy wife is an LSU graduate and we once made a small donation to the LSU Foundation. I occasionally get a cheery message asking me to donate money to the university.\nI don't respond to these messages, but if I did I would say: No thank you!\nLike blind hogs rooting for acorns", "pred_label": "__label__POS", "pred_score_pos": 0.6769876480102539}
{"content": "Abstract\nThis chapter intends to provide a reflexive discussion of the experience I loosely refer to as the ‘supervisory relationship breakdown’, which led me to withdraw from a Professional Doctorate in the penultimate year of completion. The event left an indelible impact upon me; a reminder of my blackness, the contrast between that and the ivory tower of academia and the emotional toil I endured as each incident unfolded, ultimately leading to my exit and the shattering of my emotional wellbeing. The term ‘supervisory relationship breakdown’ is a superficial reference to a complex entanglement of what I deemed to be dysconscious racism and attempts situated historically to control people of colour through education. I will explore how I as a black woman in academia believe I am perceived through a dysconscious racial lens, a lens shaped by a perception to maintain white privilege. I posit how a misalignment existed between who I am and who I was perceived to be by my doctoral supervisor. The space between this misalignment became filled with inequity, tension and oppression, culminating in the relationship breakdown. I present an ‘implosion’ of the relationship as a metaphor for the embodied affect having to withdraw from the doctorate had on me; it felt as though my ‘self’ – body, mind and spirit – were broken, in a state of collapse which I did not know how I would recover from. I conclude with support and renewed hope, I returned to academia and found an alternative approach for completing my doctorate.\nCitation\nWalker, S. (2020), \"Racism in Academia: (How to) Stay Black, Sane and Proud as the Doctoral Supervisory Relationship Implodes\", Majors, R., Carberry, K. and Ransaw, T.S. (Ed.)\nThe International Handbook of Black Community Mental Health, Emerald Publishing Limited, pp. 93-111. https://doi.org/10.1108/978-1-83909-964-920201007 Publisher:\nEmerald Publishing Limited\nCopyright © 2020 Emerald Publishing Limited", "pred_label": "__label__POS", "pred_score_pos": 0.9993226528167725}
{"content": "Hummingbird raises $8.2m led by Flourish Ventures\nHummingbird, a San-Francisco based provider of anti-money laundering (AML) compliance technology, raised $8.2 million in its Series A funding round.\nHummingbird’s products have driven efficiency gains of 80-90% in financial services providers’ workflows for investigating and reporting suspicious financial activity.\nFlourish Ventures led the round, with new support from Stripe alumni Lachy Groom and Jon Zieger.\nIt also received continued support from seed investors including Hombrew, Designer Fund, and TTV Capital, for a total funding to date of $11.8 million.\nCompliance hurdles— from navigating how regulation applies to fintech start-ups, to modernising cumbersome legacy systems— challenge financial service providers, especially as they introduce new offerings.\n“We invested in Hummingbird since its inception because it is a business at the intersection of two important trends accelerated by the pandemic – finance embedded in all our digital experiences and the digitisation of regulation,” says Kabir Kumar, director at Flourish Ventures. “The Hummingbird team cracked the code for automation in AML where others have struggled.”\nThe regtech offers two main products: a case management, investigation, and reporting platform; and an application programming interface (API) for validating and filing regulatory reports. These products aim to drive down costs, improve accuracy, and automate financial compliance programs, while also facilitating collaboration and technological advancements:\nHummingbird’s data organisation and insights are designed for machine learning.\n“Enhanced data sharing offers enormous potential in how we detect financial crime. The new funding will allow us to move forward with technologies that could improve the quality and speed of communication among institutions and leverage structured datasets, with ethical care, for machine learning,” says Hummingbird co-CEO, Joe Robinson.\n“We’re grateful for the opportunity to make regulatory compliance easier and money laundering more difficult.”\nHummingbird will also use the investment to support its expansion into new practice areas, including transaction disputes and consumer protections in lending; continue its operational growth; and enter the European market, starting with Ireland and the UK.\nIt anticipates an increase in regulatory dynamics amid COVID-19, and has made preparations to support banks and other financial institutions as the industry adapts to the pandemic’s economic stressors.", "pred_label": "__label__POS", "pred_score_pos": 0.6599249243736267}
{"content": "No symptoms of illness? You could still be carrying pathogens in your body even if you feel perfectly well, Statefoodsafety.com advises. As flu season approaches, remind your team to wash their hands thoroughly and often. To prevent cross-contamination, your handwashing sinks should be clean, easily accessible to your food workers and not used for other kitchen tasks, such as washing dishes or food items.\nArchives\nNovember 2020\nCategories\nAll", "pred_label": "__label__POS", "pred_score_pos": 0.6571725010871887}
{"content": "With all the input we receive from those around us and from the media, it can sometimes be difficult to connect with who we are at our core. Journaling enables us to sift past the clutter and learn more about ourselves—to hear the sound of our genuine nature:\nWho am I? What do I think? How do I want to live my life? What matters most to me? Why?\nWhen we know who we are, decisions become easier and we become more in sync with ourselves. And when we feed ourselves with choices that align with what matters to us, we become more at ease. This authenticity helps us identify and connect with others who live in sync with themselves, elevating our life experience.\nSunday Journal Prompt Who are you? How can you further connect with your genuine self?", "pred_label": "__label__POS", "pred_score_pos": 0.9790119528770447}
{"content": "When a single vehicle accident takes place, law enforcement agents are generally tasked with investigating the cause of the incident. While there are numerous reasons why such an accident may occur, in some cases, such an incident may lead authorities to suspect unlawful activity. A recent single-car crash in Wisconsin has left one individual facing drunk driving charges.\nAccording to reports, authorities received a call about a vehicle that had veered off the road and slammed into a tree on a recent Saturday evening. The individual who made the call also claimed the driver was exhibiting erratic behavior prior to the incident. Upon arriving at the scene, law enforcement agents found the vehicle unattended, and claim that the driver had attempted to flee the scene on foot.\nPolice located the man in the nearby woods soon thereafter, and subsequently took him into custody. He has since been charged with drunk driving, which would reportedly be his fifth offense if prosecutors secure a conviction. The penalties for a similar crime increase in severity with each successive conviction, and due to previous offenses, the man will likely be facing felony charges.\nFacing felony drunk driving charges can be a daunting experience, and those accused of such an offense may wish to prepare for what comes next by seeking advice as soon as possible. Individuals who face similar charges could retain the services of an attorney for advice in making informed decisions. An attorney in Wisconsin can evaluate the situation and assist a client in forming a strong defense for use during subsequent legal proceedings.", "pred_label": "__label__POS", "pred_score_pos": 0.9989559054374695}
{"content": "Jim Chosy, executive vice president and general counsel at U.S. Bank, was recognized last week in New York with the National Association of Women Lawyers’ “Lead By Example” award for his ongoing advocacy and commitment to advancing women attorneys. The annual award honors the exemplary leadership of a male attorney who promotes and supports the advancement of women within their company and the broader profession.\nThe support and encouragement that Chosy provides positively impacts a broad swath of legal professionals – both inside and outside the bank – and helps to empower women attorneys.\n“When women are strong, the legal profession is strong too. That’s why we must be relentless in the pursuit of full equality for women,” said Chosy. “An award hardly seems appropriate for trying to do things that feel so right, proper and necessary. But I appreciate it, very sincerely, and plan to use it as further inspiration for our work in championing women at U.S. Bank, at our provider law firms, and in the broader profession.”\nAs a strong champion of diversity, he has fostered a legal department at U.S. Bank with high female representation in senior leadership positions – including nearly 80% of his direct reports – and an equally strong presence in the leadership pipeline.\nChosy was also instrumental in creating Spotlight on Talent, a department program that provides diverse law firm associates with the opportunity to showcase their talents to attorneys responsible for making hiring decisions. Chosy recently committed to the Mansfield Rule: Legal Department Edition pilot program, an initiative that requires the consideration of diverse candidates when hiring and promoting within the Law Division and when engaging outside counsel for new matters. Additionally, he continues to advocate for our leading supplier diversity program by requiring outside counsel to meet diversity objectives.\nPast recipients of the Lead By Example Award include: Alan Bryan of Wal-Mart Stores, Mark Firestone of Kraft Foods, Jonathan Fiegelson of TIAA-CREF, David Boies of Boies Schiller & Flexner, and Judge Harold Baer of the U.S. District Court for the Southern District of New York.\nThe mission of the National Association of Women Lawyers is to provide leadership, a collective voice, and essential resources to advance women in the legal profession and advocate for the equality of women under the law. Since 1899, NAWL has been empowering women in the legal profession, cultivating a diverse membership dedicated to equality, mutual support, and collective success.\nU.S. Bancorp, with 74,000 employees and $476 billion in assets as of March 31, 2019, is the parent company of U.S. Bank, the fifth-largest commercial bank in the United States. The Minneapolis-based bank blends its relationship teams, branches and ATM network with mobile and online tools that allow customers to bank how, when and where they prefer. U.S. Bank is committed to serving its millions of retail, business, wealth management, payment, commercial and corporate, and investment services customers across the country and around the world as a trusted financial partner, a commitment recognized by the Ethisphere Institute naming the bank a 2019 World’s Most Ethical Company. Visit U.S. Bank at usbank.com or follow on social media to stay up to date with company news.", "pred_label": "__label__POS", "pred_score_pos": 0.7152249813079834}
{"content": "29\nSep 2019\nIf you're going through hell, keep going! We cannot emerge transformed if we stay stuck in the middle of the story. We must claim our power, align with spiritual principles, and move forward.\nWe have within us a voice that cheers us on, and a voice that limits us. We can challenge the inner critic, and demand it justify its stance. It will always be based on past fears.\n22\nSep 2019\nThe universe is governed by natural, physical and spiritual laws. We must align with them, in order to function well in life. We can fight the law of gravity, but we'll end up with skinned knees. We can fight the law of mathematics, but we'll end up with bounced checks.\nThe same with spiritual laws: attraction, vibration, oneness. We can use them, even if we don't fully understand them, to propel our lives along a path of our choosing.\n15\nSep 2019\nThe planet is a self-regulating system of integrated life forms. We are One with all that is. To act against any part of the whole, undermines our own position.\nSpirit only supports that which is in alignment with Itself. We must open to the next phase of development and activity, by listening to the impulse of Spirit, or be left behind.\n8\nSep 2019\nFrom One Source, the many arises. Myriad forms of life, color, music, smell, thought and ideas. All originating from the same source, a unified whole, expressing itself.\nLife is made better by the richness of the creative process. Music, art, literature, food, flowers, birds, fish. Over and over, we see the power and joy of the creative universe around, and within us, seeking expression.\n1\nSep 2019\nWhen someone pushes our buttons, we get a chance to ask the healing question. To uncover the underlying false belief behind our reaction.\nAnd then we can work from a place of Wholeness, to be authentic in the world. And do our work in integrity. And we will find that those buttons that used to control us and light us up, are no longer connected.", "pred_label": "__label__POS", "pred_score_pos": 0.7045435905456543}
{"content": "J Exp Clin Cancer Res. 2020 Aug 25;39(1):168. doi: 10.1186/s13046-020-01673-0.\nABSTRACT\nBACKGROUND: cAMP responsive element binding protein 5 (CREB5) is a transcriptional activator in eukaryotic cells that can regulate gene expression. Previously, we found that CREB5 was involved in the occurrence and development of colorectal cancer (CRC) using bioinformatics analysis. However, the biological roles and underlying regulatory mechanism of CREB5 in CRC remain unclear.\nMETHODS: Real-time PCR, western blotting, and immunohistochemistry were used to examine CREB5 expression. In vitro experiments including migration assay, wound-healing assay, chicken chorioallantoic membrane assay, and human umbilical vein endothelial cells tube formation assay were used to investigate the effects of CREB5 on CRC cell migration and tumor angiogenesis ability. Additionally, an orthotopic implantation assay was performed in nude mice to confirm the effects of CREB5 in vivo. Furthermore, gene set enrichment analysis was performed to explore the potential mechanism of CREB5 in CRC.\nRESULTS: We found that CREB5 expression was highly upregulated in CRC. CREB5 overexpression was positively correlated with advanced WHO stages and TNM stages and shorter survival in CRC patients. Moreover, CREB5 overexpression promoted while CREB5 silencing reduced the invasiveness and metastatic capacity of CRC cells both in vitro and in vivo. Furthermore, CREB5 directly interacted with the MET promoter and activated the hepatocyte growth factor-MET signalling pathway. Importantly, inhibition of MET reduced the invasion and metastasis of CREB5-overexpressing CRC cells, suggesting that CREB5 promotes metastasis mainly through activation of MET signalling.\nCONCLUSION: Our study demonstrates a crucial role for CREB5 in CRC metastasis by directly upregulating MET expression. CREB5 may be both a potential prognostic marker and a therapeutic target to effectively overcome metastasis in CRC.", "pred_label": "__label__POS", "pred_score_pos": 0.9551827907562256}
{"content": "The benefits of virtualized servers include reduced IT spending, data center space, energy costs, desktop and server provisioning and more. Despite these benefits and the estimation that the worldwide cost of cybercrime will reach $6 trillion annually by 2021, virtualization poses new risks to the data center. Read about the top 4 virtualized server threats and what you can do to mitigate your risks.\n1.) Virtual machine escape\nWhile rare, the most serious threat to virtual machine security is a hacker targeting hypervisor vulnerabilities with a virtual machine escape. It allows an OS running within it to interact with the hypervisor, providing hackers access to the host operating system. Make it a priority to regularly look for and apply vendor patch updates to reduce exposure.\n2.) Administrative access\nDespite virtualized platform efficiencies, they add management complexity. To protect against hackers who may ultimately access data center resources, secure management interfaces by tightly restricting access to the management interface.\n3.) Network Compromise\nUnusual inter-virtual machine activity or sources could be signs that your network is compromised. Create monitoring strategies, including preventive measures, intrusion detection and containment, to watch your data center networks for the slightest sign of connections from unfamiliar or unauthorized sources.\n4.) Network eavesdropping\nIn older data centers, physical switches are used to prevent network eavesdropping. In a virtualized data center, virtual switches should be designed to isolate network traffic by routing it through its respective security levels before it’s connected to the corresponding switching ports.\nWant to learn more? Read up about the seven advantages of software-defined networking, how it can increase your big data ROI and how to overcome the challenges of software-defined storage.", "pred_label": "__label__POS", "pred_score_pos": 0.6213860511779785}
{"content": "Please enter your username or the email address associated with the account so we can help you reset your password.\nData from Nielsen suggests that we are in an era of disloyalty, with more consumers trying new brands and refraining from developing long-term buying habits. This data should prove valuable to loyalty marketers, as it covers under-explored trends that create brand disloyalty, such as an increased desire to buy local in countries with prominent nationalist movements (Italy, Greece, etc.). However, Nielsen argues that “as consumers become more brand disloyal, marketers can no longer expect 20 percent of their....\nLoyalty360 members and subscribers can access a variety of content including Daily News, In-Depth Exclusives, Loyalty Management Magazine, and more.To access this content, please log in with your Loyalty360 Corporate Membership or free subscriber account.\nThank you for signing up, please check your email for more information.\nOctober 22,2020\nOctober 08,2020\nSeptember 24,2020\nMay 06,2019\nMay 02,2019", "pred_label": "__label__POS", "pred_score_pos": 0.8533962368965149}
{"content": "Abstract\nThe RNA chaperone Hfq is involved in the riboregulation of diverse genes via small RNAs. Recent studies have demonstrated that Hfq contributes to the stress response and the virulence of several pathogens, and the roles of Hfq vary among bacterial species. Here, we attempted to elucidate the role of Hfq in Acinetobacter baumannii ATCC 17978. In the absence of hfq, A. baumannii exhibited retarded cell growth and was highly sensitive to environmental stress, including osmotic and oxidative pressure, pH, and temperature. Compared to the wild-type, the Hfq mutant had reduced outer membrane vesicles secretion and fimbriae production as visualized by atomic force microscopy. The absence of hfq reduced biofilm formation, airway epithelial cell adhesion and invasion, and survival in macrophage. Further, the hfq mutant induced significantly higher IL-8 levels in airway epithelial cells, which would promote bacterial clearance by the host. In addition to results similar to those reported for other bacteria, our findings demonstrate that Hfq is required in the regulation of the iron-acquisition system via downregulating the bauA and basD genes, the stress-related outer membrane proteins carO, A1S_0820, ompA, and nlpE, and the stress-related cytosolic proteins uspA and groEL. Our data indicate that Hfq plays a critical role in environmental adaptation and virulence in A. baumannii by modulating stress responses, surface architectures, and virulence factors. This study is the first to illustrate the functional role of Hfq in A. baumannii.\nKeywords Acinetobacter baumannii Adhesion Hfq Invasion Outer membrane vesicles", "pred_label": "__label__POS", "pred_score_pos": 0.5634514093399048}
{"content": "\"Along Particular Pathways\"\nWhen the general becomes the specific, the potential for believers to faithfully walk with our Lord becomes realized and actual.\n\"Trust in the Lord with all thy heart, and lean not unto thine own understanding. In all thy ways acknowledge Him and He shall direct thy paths\" (Proverbs 3:5-6).\nResponding to Solomon's command may begin by our general acknowledgement of the Lord in \"all.\" However, we do well to specifically consider the matters of life in accordance with \"trust… lean not… acknowledge.\" This presents both great blessing and challenge, along with much opportunity for prayerful consideration and communication with God. Consider individual relationships. We do well to think of each person in our lives according to \"trust… lean not… acknowledge.\" Those with whom we share our existence do not cross our paths by accident, but rather by our Lord's purposes. Do we think of each individual accordingly? Acknowledging the Lord in specific terms requires that we do.\nWe apply this to everything in our lives, again, a calling that offers both great promise and great responsibility. Prayer, the Scriptures, fellowship with other believers, career, finances, hobbies, entertainment, bodily issues, possessions - all and more call us to \"trust… lean not… acknowledge.\" As we frequently suggest in these messages, believers do not have to be brilliant in order to walk faithfully with our Lord. But we do have to think. We must thoughtfully respond to God's presence and working in our lives. Applied faith leads to actualized faithfulness. Indeed, as we respond to the Lord and His Truth along particular pathways, we become far more likely to trust and obey Him in the power of the Holy Spirit. This offers the blessing of knowing God in the personal terms for which He redeemed us, and the practical outworking of His involved presence. He numbers the very hairs of our head (Matthew 10:30). Our Lord is obviously very specific in His involvement with us. We do well to respond in kind, pointedly trusting, leaning not, and acknowledging Him along each pathway of life.\n\"Be careful for nothing, but in everything by prayer and supplication, with thanksgiving, let your requests be made known unto God. And the peace of God which passeth all understanding shall keep your hearts and minds through Christ Jesus.\"\n(Philippians 4:6-7)\nWeekly Memory Verse\nWait on the Lord. Be of good courage and He shall strengthen thine heart. Wait, I say, on the Lord.\"\n(Psalm 27:14)", "pred_label": "__label__POS", "pred_score_pos": 0.5488449931144714}
{"content": "This timeline highlights notable research and events to give a clear overview of how thought about what autism is and how autistic people are best supported has changed over the years.\nKey:\nWhite - research studies and papers\nPurple - changes in terminology usage and diagnosis criteria\nPink - support and provision, including government strategies", "pred_label": "__label__POS", "pred_score_pos": 0.9774475693702698}
{"content": "A major element in expert sports performance, particularly racket-and-ball games, is excellent anticipatory skill. A prestudy combined the temporal and spatial occlusion paradigms to ascertain which key stimuli badminton players use for anticipating the direction of overhead shots. The main study then evaluated a program for training anticipatory skills; 200 video clips were employed to orient attention toward these key stimuli. Participants were 63 badminton novices, 20 national league players, and 21 local league players. A transparent red patch (exogenous orienting) was used to orient attention toward the trunk up to 160 ms before racket-shuttle contact; the arm, from 160 ms to 80 ms before contact; and the racket, from 80 ms before to actual contact. Results showed that badminton novices who trained with this program significantly improved their anticipatory skill between post- and retention test compared with controls. Whereas local league players improved from pre- to posttest, training had no effect on expert national league players. It is concluded that using red transparent patches to highlight the most informative cues in perceptual training programs is a promising way to improve anticipatory skill.\nThe authors are with the Department of Sport Psychology, University of Münster, Horstmarer Landweg 62b, 48149 Münster, Germany.", "pred_label": "__label__POS", "pred_score_pos": 0.8262329697608948}
{"content": "Data Driven Analysis to Drive our Understanding of Placebo Responses in Neuropsychiatric Drug Development\nTime: 12:05 pm\nday: Day One Details: Very few genetic studies have been conducted to understand individual-specific placebo response and are limited due to a lack of no-treatment control groups, using samples with heterogeneous therapeutic experiences, and relatively small sample sizes We explore and identify the challenges in Identifying genetic factors associated with individual-specific placebo response through genome-wide hypothesis-free studies on samples collected from placebo arms in CNS trials We leverage polygenic risk scores computed from large bio-banking efforts like the UKBiobank to identify risk factors that differentiate placebo responders from non-responders Discuss new approaches in analyzing response in psychiatric clinical trials and other data collection efforts to accommodate the complexity of the phenotype.", "pred_label": "__label__POS", "pred_score_pos": 0.8567373156547546}
{"content": "Image Wisely is a joint initiative of the American College of Radiology, Radiological Society of North America, American Society of Radiological Technologists and American Association of Physicists in Medicine.\nOptimizing Communication With Parents on Benefits and Radiation Risks in Pediatric Imaging\nEffective radiation risk communication can prevent and resolve potential conflicts while helping achieve effective public health safeguards. The authors discuss twelve strategies for communicating with parents/guardians that can help alleviate concerns about the iatrogenic risk associated with medical imaging using radiation exposure.", "pred_label": "__label__POS", "pred_score_pos": 0.8059026002883911}
{"content": "This paper aims to explore the application of circular economy principles for designing product refurbish operations. It adopts the desk-based research approach. The paper presents the circular economy principles formulated to support the design of product refurbish. To support the low level design, the mathematical models have been developed.\nCITATION STYLE\nRipanti, E. F., Tjahjono, B., & Fan, I. (2016). Circular economy in reverse logistics : formulation and potential design in product refurbish.\nProduction and Operations Management Society Annual Conference, (May), 1–11.", "pred_label": "__label__POS", "pred_score_pos": 0.8729490041732788}
{"content": "The rates for muscular dystrophy vary depending on the type of disease. Myotonic dystrophy is the most common form, affecting around 30,000 people in the United States. Duchenne's muscular dystrophy affects about 8,000 people in the United States. Emery-Dreifuss muscular dystrophy, on the other hand, affects fewer than 300 people. Other forms of muscular dystrophy are rarer and in some cases, rates of the diseases may be difficult to determine due to difficulty in diagnosis.\nContinue Learning about Muscular Dystrophy\nImportant: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.", "pred_label": "__label__POS", "pred_score_pos": 0.5649189949035645}
{"content": "Sometimes, an attribution story begins when a prominent individual or group makes a public statement speculating on who might be behind a cyber incident or influence operation, but without issuing a report or other evidence to support the claim. Below is the recommended workflow. How the story begins: An individual or a group uses language such as “probably X,” “we think it might be X” or “it could be X” to publicly speculate on the provenance of a cyber incident or an influence operation. If a source is publicly speculating on the parties behind a cyber incident or influence operation, but has not formally issued a report with an attribution judgment or released a dataset, ask for the methodology and proof behind their statement. If they are unable to provide this, consider carefully whether this speculation is worth reporting. Avoid amplifying attribution claims that are guesses without evidence. If you do decide that the speculation is newsworthy — perhaps because the person providing the conjecture is a prominent figure with a large audience, such as a politician claiming their campaign has been hacked — clearly state in your story that this is speculation. Reach out to the sites where the cyber incident or influence operation allegedly occurred, and ask if they have seen any evidence to support the speculation. If so, ask whether you can see the data. Either way, their answer should be included in the headline (for example, “Facebook says there is no evidence…”) and high up in the body of the story. Reach out to cybersecurity experts (and disinformation researchers, if this story involves an influence operation) to ask whether they have seen evidence to back up the speculation, or whether they can help explain any data provided by the sites in support of the speculation.The experts’ answer should be included in the body of the story. Ask someone in your newsroom, or a cybersecurity expert, to “red team” your story.", "pred_label": "__label__POS", "pred_score_pos": 0.8428484797477722}
{"content": "Regardless of the circumstances, our clients came to us concerned about preserving wealth, increasing cash flows, mitigating taxes, protecting assets, transferring assets to the next generation, and charitable giving. Each can be complicated, and they are usually interrelated.\nThey realized they needed a fresh perspective and professional guidance.\nOur background in finance and tax gives us a unique vantage point to attend to their goals and objectives. During a transition, the stakes may be high, economic opportunities can be considerable, and yet the tax ramifications can significantly alter the future economic outcome.\nClients appreciate our ability to integrate their economic objectives with the related tax mitigating opportunities. This coordination enables us to have a significant impact on their financial lives, helping them to be proactive stewards of their wealth.", "pred_label": "__label__POS", "pred_score_pos": 0.9300781488418579}
{"content": "ABSTRACT\nThe oxidoreductase RECON is a high-affinity cytosolic sensor of bacterium-derived cyclic dinucleotides (CDNs). CDN binding inhibits RECON’s enzymatic activity and subsequently promotes inflammation. In this study, we sought to characterize the effects of RECON on the infection cycle of the intracellular bacterium Listeria monocytogenes, which secretes cyclic di-AMP (c-di-AMP) into the cytosol of infected host cells. Here, we report that during infection of RECON-deficient hepatocytes, which exhibit hyperinflammatory responses, L. monocytogenes exhibits significantly enhanced cell-to-cell spread. Enhanced bacterial spread could not be attributed to alterations in PrfA or ActA, two virulence factors critical for intracellular motility and intercellular spread. Detailed microscopic analyses revealed that in the absence of RECON, L. monocytogenes actin tail lengths were significantly longer and there was a larger number of faster-moving bacteria. Complementation experiments demonstrated that the effects of RECON on L. monocytogenes spread and actin tail lengths were linked to its enzymatic activity. RECON enzyme activity suppresses NF-κB activation and is inhibited by c-di-AMP. Consistent with these previous findings, we found that augmented NF-κB activation in the absence of RECON caused enhanced L. monocytogenes cell-to-cell spread and that L. monocytogenes spread correlated with c-di-AMP secretion. Finally, we discovered that, remarkably, increased NF-κB-dependent inducible nitric oxide synthase expression and nitric oxide production were responsible for promoting L. monocytogenes cell-to-cell spread. The work presented here supports a model whereby L. monocytogenes secretion of c-di-AMP inhibits RECON’s enzymatic activity, drives augmented NF-κB activation and nitric oxide production, and ultimately enhances intercellular spread.\nIMPORTANCE To date, bacterial CDNs in eukaryotes are solely appreciated for their capacity to activate cytosolic sensing pathways in innate immunity. However, it remains unclear whether pathogens that actively secrete CDNs benefit from this process. Here, we provide evidence that secretion of CDNs leads to enhancement of L. monocytogenes cell-to-cell spread. This is a heretofore-unknown role of these molecules and suggests L. monocytogenes may benefit from their secretion in certain contexts. Molecular characterization revealed that, surprisingly, nitric oxide was responsible for the enhanced spread. Pathogens act to prevent nitric oxide production or, like L. monocytogenes, they have evolved to resist its direct antimicrobial effects. This study provides evidence that intracellular bacterial pathogens not only tolerate nitric oxide, which is inevitably encountered during infection, but can also capitalize on the changes this pleiotropic molecule enacts on the host cell. Copyright © 2018 McFarland et al.\nThis is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.", "pred_label": "__label__POS", "pred_score_pos": 0.9229421019554138}
{"content": "Cochlear implants (CI) provide opportunities for people with profound hearing impairment to recover partial hearing. An acoustic CI model based on specific stimulating strategy can be used to study sounds processed in CI, and allows test subjects with normal hearing to evaluate stimulating strategy performance. However, there is still a significant performance difference between hearing test results based on acoustic CI models and from CI users. In this study we propose to use a SPREAD matrix, which incorporates channel interaction, created by the activating function profile based on finite element models of CI to improve the acoustic CI model. According to test results, acoustic CI models with SPREAD matrix based on finite element models significantly improves its match with clinical CI data and can be used to evaluate the performance of CI stimulating strategies and predict the hearing performance of CI users more accurately.", "pred_label": "__label__POS", "pred_score_pos": 0.5889250636100769}
{"content": "Bacterial biofilms serve a vital purpose, flagging suitable homes for some marine organisms and actually aiding the transformation of larvae to adults. A new study at the California Institute of Technology is the first to describe a mechanism for this phenomenon, providing one explanation for the relationship between bacterial biofilms and the metamorphosis of marine invertebrates. This information could provide key insights for the prevention of biofouling organism growth on the hulls of ships.", "pred_label": "__label__POS", "pred_score_pos": 0.983656108379364}
{"content": "- Ad -\nLast week, the U.S. Patent and Trademark Office (USPTO) issued a memo concerning CBD products. The memo, titled\nExamination of Marks for Cannabis and Cannabis-Related Goods and Services and Enactment of the 2018 Farm Bill provides insight into how the trademark office will treat such applications.\nThe memo, which can be read in full here, begins by addressing the preliminary issue, which is that goods or services seeking registration with the USPTO must comply with federal law, regardless of the legality of the activities under state law. The memo identifies the federal laws that the products or services must comply with.\nThe memo continues to focus on this point, stating in the body of the memo “the USPTO refuses registration when an application identifies goods encompassing CBD or other extracts of marijuana because such goods are unlawful under federal law and do not support valid use of the applied-for mark in commerce.” Under federal law, cannabis is illegal.\nIt seems that applications filed on or after December 20, 2018, which are impacted by the 2018 Farm Bill, may be treated slightly different. The memo states, “For applications filed on or after December 20, 2018 that identify goods encompassing cannabis or CBD, the 2018 Farm Bill potentially removes the [Controlled Substances Act] as a ground for refusal of registration, but only if the goods are derived from ‘hemp.’ Cannabis and CBD derived from marijuana (i.e., Cannabis sativa L. with more than 0.3% THC on a dry-weight basis) still violate federal law, and applications encompassing such goods will be refused registration regardless of the filing date.”\nIn addition, the memo discusses that the 2018 Farm Bill does not make all CBD or hemp-derived products lawful. It states, “Applicants should be aware that even if the identified goods are legal under the CSA, not all goods for CBD or hemp-derived products are lawful following the 2018 Farm Bill. Such goods may also raise lawful-use issues under the Federal Food Drug and Cosmetic Act.”\nApplicants who filed before December 20, 2018 and that identified goods encompassing CBD or other cannabis products, the USPTO can reject their registration due to the lawful use or lack of bonafide intent to use in lawful commerce under the Controlled Substances Act.\nThe memo further indicates,\n“Because of the new legal definition of “hemp” under the 2018 Farm Bill, the applicant will also be required to amend the identification of goods to specify that the CBD or cannabis products contain less than 0.3% THC. If the applicant elects to amend the application, the examining attorney will conduct a new search of the USPTO records for conflicting marks based on the later application filing date. TMEP §§206.01, 1102.03. The examining attorney will also advise the applicant that, in lieu of amending the application, it may elect to abandon the subject application and file a new application. Alternatively, the applicant may respond to the stated refusal by submitting evidence and arguments against the refusal.”\nAll information is for general informational and educational purposes only. Nothing should be interpreted as legal or wellness advice.", "pred_label": "__label__POS", "pred_score_pos": 0.8461498618125916}
{"content": "/ by UK HealthCare\nIt's an irrefutable fact that smoking is bad for you. Study after study has proven that smoking increases your risk for cancer, heart disease, diabetes – even blindness.\nBut dementia? Not so fast. A recent study has demonstrated that smoking is not associated with a higher risk of dementia.\nMany previous studies have found a correlation between smoking and dementia. However, Erin Abner of the UK Sanders-Brown Center on Aging (SBCoA) and colleagues wanted to explore outcomes using a different method of data analysis.\n\"The underlying data [in those studies] was solid, but the analysis didn't take into account the idea of competing risk of mortality, which we felt was an important factor to consider with smoking,\" Abner said. \"In this case, if smoking kills someone before they show signs of dementia, how can you accurately count that person? We think those deaths should be accounted for when predicting dementia risk.\"\nThe research team examined 531 people who were part of the SBCoA BRAiNS study, which follows hundreds of volunteers to explore the effects of aging on cognition. They used a statistical method called Competing Risk Analysis to determine whether there was a connection between smoking and dementia once the competing risk of death was included.\nThe answer: There wasn't.\n\"To be clear, we are absolutely not promoting smoking in any way,\" said Abner, who also holds a faculty appointment in the UK College of Public Health. \"We're saying that smoking doesn't appear to cause dementia in this population.\"\nThe data was published in the March 26, 2019 issue of the Journal of Alzheimer's Disease (JAD-68 (2)).", "pred_label": "__label__POS", "pred_score_pos": 0.6829345226287842}
{"content": "24 hours per day, 7 days per week, 365 days per year. A lot of our customers’ operations need to run smoothly around the clock, which makes equipment reliability and having a flexible service partner crucial.\nWhen one of our long-standing planer mill customers was in need of servicing for their Sullair, LLC compressors and dryers, without disrupting their 24-hour production schedule, Chamco jumped into action.\nWe formulated a plan that allowed us to complete the required maintenance within the limited planned outages available. The customer appreciated Chamco’s ability to accommodate their schedule and our understanding that sometimes downtime is not an option.", "pred_label": "__label__POS", "pred_score_pos": 0.8128154873847961}
{"content": "Smallholder farmers and forest-dependent communities have the power to protect the planet’s resources while also contributing to sustainable rural development.\nBuilding upon years of exploratory grantmaking, research, and engagement with local communities, we are exploring solutions that balance agricultural economic opportunities with environmental sustainability through the Agriculture, Livelihoods, and Conservation strategy. Our work builds on the Foundation’s experience with climate and land use, and our work in reproductive health.\nOur grantee partners protect forests and biodiversity while ensuring that people who rely on them can thrive by supporting sustainable smallholder agriculture.", "pred_label": "__label__POS", "pred_score_pos": 0.6853921413421631}
{"content": "Agribusiness dispute\nThe Client is a cattle station owner who took on Agistment cattle for his Neighbour. Unknown to the Client, the Cattle were subject to a stock mortgage in favour of a Bank. The Neighbours subsequently divorced with the wife claiming rights to the cattle. The Client was owed a substantial amount for Agistments fees. The Bank had also issued notices making claim to the cattle for unpaid loans owing by the Neighbour.\nIssue:\nThe issue was who had a right to the cattle and to be paid first? Was it the bank, who had a registered stock mortgage, the wife who had a legitimate family law claim, or the client who was owed agistment fees? Did the Client have any rights to the Cattle or could the Bank enter the Client’s land and take the Cattle.\nAction:\nRather than litigating the issue, the Client opted for a mediation with all competing parties in attendance. The Client claimed a Possessory Lien over the stock following breach of the Agistment Agreement by the Neighbour, and further that the possessory Lien prevailed over the Banks registered Mortgage. The Law on whether the Bank’s registered Lien prevailed over the possessory Lien was uncertain.\nNot favouring the Client was whether his agistment obligations improved the stock or whether his efforts went merely to the maintenance of stock. The former gave a right to a possessory Lien, the later did not. The advice to the client was to not under any circumstance relinquish possessory rights to the cattle but to force the hand of the bank and the Neighbours. The Client also claimed a Statutory Lien under the Storage Liens Act 1973 claiming a right to sell after giving notice.\nResult:\nThe Bank contributed feed and lick to the cattle at no charge and released their interest in the cattle to the Client, who purchased same in satisfaction of the Neighbours debt, later on selling it for a substantial profit. Achieving the result required a thorough understanding on the law of securities and the precise terms of the Agistment Agreement.", "pred_label": "__label__POS", "pred_score_pos": 0.7178964614868164}
{"content": "Our daily routines include the use of hot water, whether that is to prepare a cup of coffee or to take a warm shower before getting into bed. Warm water helps you wash dishes faster, and at the office, it allows your employees to keep their hands clean at a more effective level. There are several options for heating up water. While a geyser remains a popular option, many people are looking at alternative solutions.\nThe installation of boilers and water heaters can often result in a more cost-effective option when providing hot water to a building. These systems provide appropriate functionality for home use but also doubles as ideal options for commercial buildings. The installation process for these systems tend to be similar to a geyser, but there are a few benefits that you might want to take into consideration.\nWhen it comes to fitting your building with these systems, a few things should be looked at first. You need to ensure the system you buy will be compatible with your plumbing solution. At the same time, you want to ensure the system will provide the most efficient use in your environment.\nStart by considering the differences that exist between the two options.\nA water heater consists of a tank. These tanks come in various models and sizes, so you have some flexibility to help you meet the demands of your building. Electricity or gas can then be used to heat up the water inside the tank. The water can then be distributed appropriately to areas throughout your home or at an office.\nBoilers work a bit differently compared to water heaters. The maximum temperature in boilers will generally be much higher compared to a standard heating system. Certain boilers can also help with the process of converting water into steam.\nThe Furnace Outlet offers a range of boilers and water heaters that are designed to meet your needs. We are top-rated among furnace wholesalers and offer all of our products at lower prices compared to retail stores. We can supply both complete packaged systems, as well as individual parts and accessories. This makes the process of finding furnace repair near me easier – as you now have a more affordable source for the parts needed during the repair process.\nIt is important to take a moment to contact a professional HVAC installer in your area before buying a boiler or water heater system. Provide the installer with details of your expectations to ensure they can help you find the right model in our catalog.", "pred_label": "__label__POS", "pred_score_pos": 0.5772473812103271}
{"content": "Introduction: The prognosis of breast cancer is strongly influenced bythe developmental stage of the breast when the tumor is diagnosed.Pregnancy-associated breast cancers (PABCs), cancers diagnosed during pregnancy,lactation, or in the first postpartum year, are typically found at an advanced stage,are more aggressive and have a poor... read moreer prognosis. Although the systemic andmicroenvironmental changes that occur during post-partum involution have been bestrecognized for their role in the pathogenesis of PABCs, epidemiological data indicatethat PABCs diagnosed during lactation have an overall poorer prognosis than thosediagnosed during involution. Thus, the physiologic and/or biological events duringlactation may have a significant and unrecognized role in the pathobiology ofPABCs.\nKeywords: adipose stromal cells, adipose stromal cells derived frominvoluting mammary glands, adipose stromal cells derived from lactating mammaryglands, adipose stromal cells derived from nulliparous mammary glands, adiposestromal cells derived from pregnant mammary glands, adipose stromal cells derivedfrom regressed mammary glands, bovine serum albumin, carcinoma-associated fibroblast,carcinoma-associated fibroblast-like, conditioned media, cellular retinoic acidbinding protein 1, 4′,6-diamidino-2-phenylindole, (Dulbecco's) modified Eagle'smedium, fatty acid binding protein 4, gene set enrichment analysis, hemotoxylin andeosin, hormone sensitive lipase, human umbilical cord endothelial cell, interleukin6, Krupple-like factor 2, mouse heart endothelial cell, matrix metalloproteinase 9,non-obese diabetic severe combined immunodeficient, pregnancy-associated breastcancers, phosphate-buffered saline, platelet-derived growth factor C, placental-likegrowth factor, peroxisome proliferator-activated receptor gamma, preadipocyte factor1, Penicillan/Streptomycin, Fungicide, Reduction mammoplasty adipose, reversetranscriptase polymerase chain reaction, stem cell antigen 1, standard error of themean, small hairpin CRABP1, small hairpin scrambled, thyroid response element,vascular endothelial growth factor A, vascular endothelial growth factor C, vascularendothelial growth factor D.\nMcCready, Jessica, Lisa M. Arendt, Eugene Glover, VandanaIyer, Jerrica L. Briendel, Stephen R. Lyle, Stephen P. Naber, Daniel G. Jay, andCharlotte Kuperwasser. \"Pregnancy-associated breast cancers are driven by differencesin adipose stromal cells present during lactation.\" Breast Cancer Research 16, no. 0(2, 2014): 1-19.", "pred_label": "__label__POS", "pred_score_pos": 0.6460868120193481}
{"content": "A quick review of the Adult BLS Algorithm to study before taking your ACLS test.\nWhile the Adult BLS Algorithm is classified as a Basic Life Support (BLS) algorithm, it is undoubtedly an algorithm you need to be familiar with in order to pass your Advanced Cardiac Life Support (ACLS) exam. This is because there is a relatively high degree of carry-over between the two courses. Thus, it’s important to know the BLS steps in sequence to improve your odds of passing your ACLS test.\nBLS emphasizes early CPR and defibrillation using an AED. The primary goal of the Adult BLS Algorithm is to improve the chances of survival by ensuring adequate oxygenation, ventilation, and circulation. The Adult BLS Algorithm provides the necessary steps for both single-rescuer and multiple rescuer scenarios of an unresponsive adult. But you might still be wondering, what are the steps I need to know? And how are all these steps connected?\nWhat are the BLS steps used for adults?\nLay people and first-time trainees may ask themselves: what is the difference between BLS and CPR? And the answer is simple, generally speaking, BLS is advanced CPR and AED care provided by healthcare workers. The steps, in turn, are similar to those in CPR, with the new BLS guidelines focusing on the rate and depth of compressions (100-120 per minute, 2-2.4 inches deep) defibrillation, and the use of one-way valve barrier devices for rescue breathing.\nFor detailed information, refer to the Adult BLS Algorithm below:\nBefore beginning:\nCheck for scene safety and victim responsiveness. Call for emergency medical help, and if available, bring an AED to the patient. If the patient has a normal pulse and is breathing normally, stay with the patient, and monitor their condition until the arrival of emergency medical services.\n1. Circulation:\nCheck the patient for a pulse:\n-\nIf no pulse is detected, begin delivering CPR. Place palms in the center of patients chest with one hand over the other and with arms locked, allowing the chest to fully rise between compressions, push down hard and fast to a depth of 2-2.4 inches at a rate of 100-120 compressions per minute (30 every 15-18 seconds) giving 2 rescue breaths for every 30 compressions.\n-\nIf a pulse is detected, move to the airway section of the algorithm\n2. Airways: 2. Airways:\n- If the patient is breathing adequately, maintain the patient’s airway, and place them in the recovery position.\n- If you witnessed the collapse and can safely assume there is no spine injury, perform the chin lift maneuver to open the airway.\n- If you did not witness the collapse or the collapse was caused by trauma, use the jaw thrust method.\n- If a foreign object is blocking the airway remove the object either by inserting a finger into the mouth and scooping it out if easily accessible, otherwise perform abdominal thrusts to clear the obstruction.\n3. Breathing: 3. Breathing:\nBreathing regularity should be first assessed while assessing responsiveness and should be monitored throughout care, always use a barrier device when available.\n-\nIf the patient has a pulse, begin rescue breathing immediately. If no CPR is required perform one rescue breath every six seconds (10 breaths per minute), and check pulse every two minutes.\n-\nIf the patient has no pulse, and rescue breathing is part of CPR, ensure a good seal over the patient's mouth with either your mouth or barrier device, pinch their nose closed, and deliver one-second-long rescue breaths ensuring the chest rises and falls with each breath.\n4. Defibrillate: 4. Defibrillate:\nWhen the Automated External Defibrillator (AED) arrives, turn on the unit and follow the verbal prompts, firmly attach the fads to the patient's chest, and allow the AED to analyze the patient's heart rhythm.\n-\nIf shock is required, ensure all responders have hands clear from the patient to avoid shocks before administering shock. Press the shock button when all hands are clear. After the shock has been administered, resume delivery of CPR.\n-\nIf AED determines against shock, initiate CPR and recheck rhythm after 5 cycles.", "pred_label": "__label__POS", "pred_score_pos": 0.8929936289787292}
{"content": "Understanding Psychological Evaluations for Workers’ Comp in Indiana\nIf a workers’ comp issue stems from or causes a mental health issue, you need strong representation from a knowledgeable team in order to receive your proper reward. The Indiana Workers’ Compensation Evaluation is a common component of Indiana workers’ comp cases and you do not have to fear them. They determine the proper category for your claim and the appropriate compensation you deserve for it.\nWhy Psychological Evaluations? You have rights if: A work condition or event causes mental distress and psychological disorder. A physical injury at work leads to anxiety, depression or post-traumatic stress disorder (PTSD). A mental or psychological disorder leads to inability to function at work, even if that disorder does not originate at work. Psychology Services and Workers’ Comp\nEmployees may be alarmed, even offended, when employers and labor reviewers scrutinize their injury claims. Psychological evaluations insure understanding of the extent of the injured employee’s condition and elimination of fraud cases. Psychologists or psychology services specializing in work-based injury can prevent your case from being discredited.\nThey understand how physical injuries correlate to life changes and psychological disordering. They can recognize complex PTSD, brain injury and depression symptoms that prevent functioning at work. They can discern credible symptoms and disabilities from exaggerated ones to substantiate your rights to compensation.\nThe Indiana Workers’ Compensation Evaluation Process\nPsychological services help show a disability prevents you from working for short and long terms or that a disability arose from your job. Psychologists provide trusted opinions to validate your symptoms and claims.\nThey may interview you several times. They may also speak with bosses, supervisors and coworkers. They may recommend physical examinations and further psychiatric evaluation or treatment. Finally, they may work with your workers’ comp attorney to present their findings in your best interests.\nGood psychological services in Indiana can help you secure your workers’ comp reward. Contact us for more information, here.", "pred_label": "__label__POS", "pred_score_pos": 0.5984537601470947}
{"content": "Abstract\nBackground: Hypomethylating agents (HMA), azacitidine, and decitabine are frequently used in the management of myelodysplastic syndromes (MDS). However, there are no clinical trials that have directly compared these agents. We conducted a systematic review and indirectly compared the efficacy of azacitidine to decitabine in MDS. Methods: We conducted a comprehensive search of several databases (MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, and Scopus) through June 28, 2018, without language or time restrictions. Studies were screened by two independent reviewers, and differences were resolved by consensus. The fixed effect model and adjusted indirect comparison methods were used to pool relative risks (RR) of major outcomes of interest (mortality, response rate, quality of life, hematologic improvement, hospitalization, leukemia transformation, transfusion independence). Results: Only four trials met the eligibility criteria. Two trials compared azacitidine to the best supportive care (BSC) and included 549 patients, and the other two compared decitabine to BSC and included 403 patients. The risk of bias was unclear overall. Compared to BSC, azacitidine was significantly associated with lower mortality (RR = 0.83, 95% CI 0.74-0.94, I\n2 = 89%) whereas decitabine did not significantly reduce mortality (RR = 0.88, 95% CI 0.77-1.00, I 2 = 53%). Both drugs were associated with higher partial and complete response compared to BSC. Indirect comparisons were not statistically significant for all the studied outcomes, except for complete response where azacitidine was less likely to induce complete response compared to decitabine (RR = 0.11, 95% CI = 0.01-0.86, very low-certainty evidence). Conclusions: Azacitidine and decitabine are both associated with improved outcomes compared to BSC. The available indirect evidence comparing the two agents warrants very low certainty and cannot reliably confirm the superiority of either agent. Head-to-head trials are needed. In the meantime, the choice of agent should be driven by patient preferences, adverse effects, drug availability, and cost. Keywords Azacitidine Decitabine Myelodysplastic syndromes Network meta-analysis ASJC Scopus subject areas Medicine (miscellaneous)", "pred_label": "__label__POS", "pred_score_pos": 0.850510835647583}
{"content": "Microsoft Teams provides a secure platform for remote professionals to communicate. It provides access to video and audio conferencing functionality based on tiered subscription plans. The application allows organizations with multiple locations to use auto dial-in numbers based on the location of teams. Numbers are transferable to Teams for audio conferencing.\nMy team and I at ChaceTech have identified some issues that some companies faced and managed to resolve while using Microsoft Teams.\nConnecting Video Conferencing Endpoints\nAs an increased number of companies turned to online meetings due to restrictions triggered by the Covid-19 pandemic, they learned lessons on how to use MS Teams more effectively. Some organizations faced issues when trying to connect video conferencing endpoints for Cisco into Teams meeting.\nFortunately, they discovered that Microsoft provides a viable solution for this challenge – Cloud Video Interop (CVI). This solution simplifies the process by providing the information needed to dial-in the video cart. CVL information is available at the bottom of the meeting invite.\nAn additional issue is the lengthy dial-in string, which requires considerable effort to enter into the video unit. CVI providers can help resolve the problem using the one button to push (OBTP), which schedules meetings using Microsoft Exchange. The solution employs an API to deliver details of the meeting to video endpoints. Once the endpoints are complete, you will find the video quality impressive.\nOrganizing Teams\nThe presence of too many teams can lead to low visibility issues. If you establish multiple channels for various departments or processes, the teams may change, disappear, and members join or leave abruptly. Fortunately, you can resolve these problems by linking teams to business units or products, not people.\nThe source of the chaos is due to people collaborating on different projects. Teams linked to the people malfunction when an individual changes projects. Hence, the need for improved channel naming conventions.\nMissing Information\nThe synchronous nature of the chat function in Microsoft Teams can hide some of the information. Users face this issue after spending time away from the platform, and messages accumulate. By the time a user checks messages, important information may be missing, and everything appears in bold or has circled numbers.\nCompanies faced with this problem quickly realized the difference between real-time chat and email. The chat function in Teams is ideal for real-time conversations or broadcasting notices. Email is asynchronous and the right solution for messages that require a focus on a single topic. Chat does not come with a subject line.\nVariable Adoption\nIn some cases, various departments responded differently to the introduction of Microsoft Teams for communication and collaboration. Some departments felt that the platform solved their communication challenges. Others expressed concern that the change brings more work to their tight schedules.\nOrganizations resolved this adoption issue by incorporating various projects that are useful to different departments. The projects solve specific problems for team members. A generic or one size fits all approach to use cases undermines adoption levels. The mere ability for everyone to interact in a channel is not compelling to everyone.\nA Recap of Microsoft Teams Lessons Learned\nWhen faced with challenges connecting endpoints for Cisco video conferencing, use the Cloud Video Interop (CVI). On the other hand, adopt proper channel naming conventions when dealing with too many channels and teams. Linking teams to individuals instead of business units, campaigns, and projects causes chaos as the individual switches from one project or channel to another.\nThe chat function in MS Teams cannot mimic the asynchronous nature of email for topics that require greater focus. Use chat for real-time conversations involving a wide variety of topics.\nEnlisting the assistance of a managed IT service provider is another way to resolve challenges in Microsoft Teams. Vendors can assist in setting up and configure various features in the communication platform.", "pred_label": "__label__POS", "pred_score_pos": 0.6973960399627686}
{"content": "Services ‘Boofey’, my 18 1/2-year-old Cattle X Kelpie I have experienced several losses in my life, be it pets or people, family or friends.\nThese experiences brought about a sense of isolation and emptiness but it wasn’t until I lost my faithful companion ‘Boofey’, a 18 1/2-year-old Cattle X Kelpie, which in a few words brought me to my knees, that I turned my attention towards grief counselling and pet loss support.\nI provide counselling and support for people of all ages, both young and older, who are dealing with expected or unexpected pet loss including:\nmaking end of life decisions, grieving for your pet (prior or post-loss), being with you and/or your pet at your vet/at home (for those in Penrith, NSW and surrounds), deciding whether you are ready for another pet.\nSessions are 1 hour in duration and can be held face to face in Luddenham, NSW, in-home or at your veterinary clinic, or alternatively I can arrange online or telephone consultations for those who cannot travel or struggle with balancing time. Rebates are also available to eligible members of Medibank Private and Doctors Health Fund (please refer to your policy for further details).\nMy approach is deeply person-centered, utilizing narrative practices in remembering those we have lost. The narrative approach in particular helps to resurface and maintain positive connections following the loss of a beloved pet and companion. I also work with a trauma-sensitive lens ensuring to keep each person I meet feeling safe. I have established By My Side for those seeking comfort and, I understand that everyone has their own unique story. You can tell your story, and be heard.\nPlease note By My Side is not a crisis counselling service. If you are in a crisis please contact:\nLifeline on 13 11 14 or Suicide Call Back Service 24/7 on 1300 659 467.", "pred_label": "__label__POS", "pred_score_pos": 0.738516092300415}
{"content": "The EU’s biggest research and innovation program, Horizon 2020 (H2020), invested over €41m ($48.4m) in pharmaceutical R&D grants for projects between May 2019 and April 2020, with over €27m ($.31.8M) allocated for the development of promising early stage drug and vaccine candidates, according to data from GlobalData’s Pharma Intelligence Center News Database. In response to the Covid-19 pandemic, H2020 invested almost €6m ($7.1m) for Covid-19-related research and drug development in April 2020. The EU’s H2020 program, which has been running since 2014 with a €80bn ($94bn) budget, was established to support R&D contributing to Europe’s global competitiveness in research and innovation.\nAccording to GlobalData’s Pharma Intelligence Center News database, the majority of these H2020 pharmaceutical R&D grants were for advancing early stage drug development, which received over €27m ($31.8m) (66%), rather than early drug discovery research, which only received approximately €14m ($16.5m) (34%) (Figure 1). This reflects a strong focus in helping promising candidates move toward clinical development and commercialisation. All pharmaceutical R&D grants awarded between May 2019 and April 2020 pertained to the Infectious Disease therapy area. H2020 invested almost €6m ($7.1m) on three Covid-19-related projects from January to February 2020, with the aim to accelerate efforts to develop effective treatments and vaccines in response to the pandemic.\nItalian Bio/Pharma company Dompe Pharmaceuticals SPA that concentrates on rare and orphan diseases received approximately €3m ($3.5m) for early discovery research aiming to find new treatment options for Covid-19, and Helmholtz Zentrum Munchen German Research Center for Health and Environment GmbH, a key subsidiary of Helmholtz Association of German Research Centers, received approximately €1m ($1.2m) for Covid-19. Austria-based Apeptico received over €1.5m ($1.8m) funding for repurposing its Phase II candidate solnatide for Covid-19, which subsequently received regulatory approval by the Italian Medicines Agency for the treatment of Covid-19 patients suffering from pulmonary edema and acute respiratory distress syndrome in May 2020.\nOther companies such as Swiss biotech company BioVersys AG, developing a drug for tuberculosis, and German Helmholtz Center for Infection Research, developing vaccines for influenza and Chagas Disease, received a combined funding of approximately €25m ($29.5m), demonstrating a focus on funding for diseases identified in the World Health Organization’s (WHO’s) Priority Medicines for Europe and the World Update Report, 2013. More details about these pipeline drugs can be found in the GlobalData Pharma Intelligence Center Drugs Database.\nH2020 aims to deliver breakthroughs and discoveries by helping ideas move from the lab to the market. The program prioritises projects that address priority diseases for Europe and the world, where biopharmaceutical companies can take their innovative early stage approaches through clinical development and commercialisation. Given the global health threats posed by Covid-19, the EU has vowed to invest €1bn ($1.2bn) into research and innovation by 2020, and had already invested €458.9m ($541.2m) by September 2020 in developing new vaccines, medicines, medical devices, and other technologies and tools to help bring the Covid-19 pandemic under control.", "pred_label": "__label__POS", "pred_score_pos": 0.7800236344337463}
{"content": "The agenda for this IHRF event featured international speakers from the UK and the Netherlands who shared their countries’ experiences of prioritising areas of health research for State funding. We were also joined by national experts and had discussion time to debate this complex question.\nPresentations- Matt Westmore & Prof Pancras Hogendoorn", "pred_label": "__label__POS", "pred_score_pos": 0.8347663879394531}
{"content": "Abstract\nTo identify cell-surface markers specific to human cardiomyocytes, we screened cardiovascular cell populations derived from human embryonic stem cells (hESCs) against a panel of 370 known CD antibodies. This screen identified the signal-regulatory protein alpha (SIRPA) as a marker expressed specifically on cardiomyocytes derived from hESCs and human induced pluripotent stem cells (hiPSCs), and PECAM, THY1, PDGFRB and ITGA1 as markers of the nonmyocyte population. Cell sorting with an antibody against SIRPA allowed for the enrichment of cardiac precursors and cardiomyocytes from hESC/hiPSC differentiation cultures, yielding populations of up to 98% cardiac troponin T-positive cells. When plated in culture, SIRPA-positive cells were contracting and could be maintained over extended periods of time. These findings provide a simple method for isolating populations of cardiomyocytes from human pluripotent stem cell cultures, and thereby establish a readily adaptable technology for generating large numbers of enriched cardiomyocytes for therapeutic applications.", "pred_label": "__label__POS", "pred_score_pos": 0.965999186038971}
{"content": "A team led by a biomedical scientist at the University of California, Riverside has found a new mechanism responsible for the abnormal development of neuronal connections in the mouse brain that leads to seizures and abnormal social behaviors.\nThe researchers focused on the area of the brain called hippocampus, which plays an important role in learning and social interactions; and synapses, which are specialized contacts between neurons.\nEach neuron in the brain receives numerous excitatory and inhibitory synaptic inputs. The balance between excitation and inhibition in neuronal circuits, known as E/I balance and thought to be essential for circuit function and stability and important for information processing in the central nervous system, can play a role in causing many neurological disorders, including epilepsy, autism spectrum disorder, and schizophrenia.\nThe researchers also focused on a protein called ephrin-B1, which spans the membrane surrounding the cell and plays a role in maintaining the nervous system. The goal of their study was to determine if the deletion or over-production of ephrin-B1 in astrocytes—glial cells in the brain that regulate synaptic connections between neurons—affects synapse formation and maturation in the developing hippocampus and alters the E/I balance, leading to behavioral deficits.\n\"We found the changes in the E/I balance are regulated by astrocytes in the developing brain through the ephrin protein,\" said Iryna Ethell, a professor of biomedical sciences in the UCR School of Medicine who led the mouse study. \"Further, astrocytic ephrin-B1 is linked to the development of inhibitory networks in the hippocampus during a critical developmental period, which is a new and unexpected discovery. Specifically, we show the loss of astrocytic ephrin-B1 tilts the E/I balance in favor of excitation by reducing inhibition, which then hyperactivates the neuronal circuits. This hyperactivity manifests as reduced sociability in the mice and suggests they can serve as a new model to study autism spectrum disorder.\"\nThe findings, published in the\nJournal of Neuroscience, can further scientists' understanding of the mechanisms that lead to neurodevelopmental disorders, allowing researchers to discover novel interventions for treating these disorders by targeting astrocytes during a specific developmental period.\nEthell explained that astrocyte dysfunctions are also linked to synapse pathologies associated with neurodevelopmental disorders and neurodegenerative diseases such as Alzheimer's disease where early dysfunction in synaptic connections can also lead to neuron loss.\n\"How exactly astrocytes use the ephrin protein to control the development of neuronal networks remains to be explored in future studies,\" she said. \"Our findings open a new inquiry into future clinical applications as impaired inhibition has been linked to several developmental disorders, including autism and epilepsy.\"\nThe report is first to establish a link between astrocytes and the development of E/I balance in the mouse hippocampus during early postnatal development.\n\"We provide new evidence that different ephrin-B1 levels in astrocytes influence both excitatory and inhibitory synapses during development and contribute to the formation of neuronal networks in the brain and associated behaviors,\" Ethell said.\nShe explained that synapses are building blocks of neural networks and function as fundamental information-processing units in the brain. Excitatory synapses are cell-cell connections that facilitate neuronal activity, she said, whereas inhibitory connections negatively regulate brain activity to coordinate brain responses, their timing, and specificity.\n\"Hyperactivity of neuronal networks resulting from the loss or impaired function of inhibitory synapses can lead to neural dysfunctions and seizures,\" she added. \"Like a car without brakes, the brain without inhibitory neurons cannot function properly and becomes overactive, resulting in loss of body control.\"\nEthell acknowledged further investigation is needed to determine how exactly ephrin signaling in astrocytes alters inhibitory synapses, and specifically how astrocytes may contribute to these mechanisms.\n\"Given the widespread and growing research interest in the astrocyte-mediated mechanisms that regulate E/I balance in neurodevelopmental disorders, our findings establish a foundation for future studies of astrocytes in clinically relevant conditions,\" she said.\nMore information: Amanda Q Nguyen et al, Astrocytic ephrin-B1 controls excitatory-inhibitory balance in developing hippocampus, The Journal of Neuroscience (2020). DOI: 10.1523/JNEUROSCI.0413-20.2020 Journal information: Journal of Neuroscience\nProvided by University of California - Riverside", "pred_label": "__label__POS", "pred_score_pos": 0.7089226841926575}
{"content": "Gergana Petrova Romanova\nPhD Student\nSection for Production, Markets and Policy\nRolighedsvej 25, 1958 Frederiksberg C, Bygning C, stuen, Building: 0.204\nORCID:0000-0002-0524-7059\nIn my PhD, I explore the phenomena of university-industry collaborations, applying innovation management and organizational theory lenses. In the qualitative investigation I am conducting, I collect data on the level of the management of the university and at a collaborative project level – projects where university scientists collaborate on research projects with industry partners. Interviews with project participants and observations conducted during collaborative project meetings and advisory board meetings comprise the larger chunk of my data set. However, initially I started by looking at the local institutional settings to understand how collaborations are perceived, initiated and supported. As I delve into the individual research projects, I aim to understand how university-industry collaborative research projects are managed in practice. I base my individual articles of the dissertation on these different empirical settings and points. As this is an inductive study and I have let the data to lead the process of investigation, I have currently found the notion of\nopenness to guide my research and further data collection. Openness, I found, plays out in fascinating ways when exploring the way middle and top management work towards developing university strategy with focus on the three missions of the university, and particularly on the third mission of innovation and creating impact to society. Additionally, I am interested in understanding how open innovation and open science are practiced in the collaboration between scientists and their industry partners in the individual projects. Teaching\nI teach in the MSc course of Entrepreneurship and Innovation and the Food Innovation & Entrepreneurship course (part of the MSc in Integrated Food Studies). The topics I cover span across Business Models, Business Model Canvas, Lean Start-up Approach, Venture Financing and Business Planning.\nSupervision\nI co-supervise MSc students across natural science fields who work on their Projects In Practice and master’s theses with focus on innovation & entrepreneurship.\nID: 182562812", "pred_label": "__label__POS", "pred_score_pos": 0.6162512898445129}
{"content": "Federal Income Tax Bankruptcy Laws\nIncome taxes and bankruptcy are common but strange companions. As the Internal Revenue Service (IRS) becomes more user friendly, individuals and business owners finally have a bit of flexibility in paying or receiving forgiveness of taxes due. People should, nevertheless, become familiar with this relationship and learn the laws that apply. Maximizing cash and minimizing stress should result.\nIncome Tax\nThe only tax that can be considered for discharge (elimination) is the income tax. Only individuals, not businesses, have the opportunity for income tax forgiveness. However, small businesses that are sole proprietorships, with all income recorded as individual compensation for income tax purposes, often qualify for elimination in a Chapter 7 bankruptcy. Therefore, some or all income tax due may be eliminated if the taxpayer qualifies.\nChapter 7 Versus Chapter 13\nWhile there may be some ability to discharge income taxes as part of a Chapter 7 (liquidation) bankruptcy, there is no provision for elimination of taxes with a Chapter 13 (wage earner) petition. Chapter 13, which allows the petitioner to pay a reduced amount to creditors over a three- to five-year period, requires that all income taxes be paid in full (no discount or percentage) during the bankruptcy term.\nTaxes That May Qualify For Discharge in a Chapter 7 Bankruptcy\nIncome taxes due prior to three years before filing a bankruptcy petition may be discharged. Those taxes for individual returns that were (or should have been) filed within the three years immediately preceding a bankruptcy filing cannot be discharged. Non-dischargeable income taxes also include tax applicable to returns filed late and within two years of the bankruptcy filing. Add taxpayers who are suspected of committing fraud on their returns to the list of non-dischargeable income taxes. Other income tax obligations should, however, be dischargeable. Always consult with an experienced tax advisor before making any final assumptions regarding dischargeability. However, businesses do not qualify for tax forgiveness.\nIncome Tax Liens\nIncome tax bankruptcy laws prohibit discharging obligations after liens have been filed and recorded. Past due taxes, for which the IRS files liens against real estate and personal or business property, become secured debts. Creditors having properly acquired security must receive payment or physically take possession of the security to satisfy their debts. Should the IRS file a valid lien against the taxpayer’s property for delinquent tax payments, these income taxes cannot be discharged.\nCompetent Advice Required\nWhile many bankruptcies are straightforward and relatively simple, when income taxes are a component, individual and business cases can easily become complex. For example, most other taxes, e.g., payroll taxes collected by a business, are never dischargeable in bankruptcy. However, questions arise with small businesses that are sole proprietorships or C corporations, where all profits are distributed to the owners as compensation. The most important rule is to get experienced, correct advice from tax advisors, be they accountants, attorneys or other qualified professionals. Whenever possible, consult with one or more experts before filing for bankruptcy. Proper planning and knowledge can help avoid income tax traps during a bankruptcy.", "pred_label": "__label__POS", "pred_score_pos": 0.5088756680488586}
{"content": "Notice:Users may be experiencing issues with displaying some pages on stanfordhealthcare.org. We are working closely with our technical teams to resolve the issue as quickly as possible. Thank you for your patience. Journal of neuro-oncologyLober, R. M., Cho, Y., Tang, Y., Barnes, P. D., Edwards, M. S., Vogel, H., Fisher, P. G., Monje, M., Yeom, K. W. 2014; 117 (1): 175-182 Abstract\nWhile pediatric diffuse intrinsic pontine gliomas (DIPG) remain fatal, recent data have shown subgroups with distinct molecular biology and clinical behavior. We hypothesized that diffusion-weighted MRI can be used as a prognostic marker to stratify DIPG subsets with distinct clinical behavior. Apparent diffusion coefficient (ADC) values derived from diffusion-weighted MRI were computed in 20 consecutive children with treatment-naïve DIPG tumors. The median ADC for the cohort was used to stratify the tumors into low and high ADC groups. Survival, gender, therapy, and potential steroid effects were compared between the ADC groups. Median age at diagnosis was 6.6 (range 2.3-13.2) years, with median follow-up seven (range 1-36) months. There were 14 boys and six girls. Seventeen patients received radiotherapy, five received chemotherapy, and six underwent cerebrospinal fluid diversion. The median ADC of 1,295 × 10(-6) mm(2)/s for the cohort partitioned tumors into low or high diffusion groups, which had distinct median survivals of 3 and 13 months, respectively (log-rank p < 0.001). Low ADC tumors were found only in boys, whereas high ADC tumors were found in both boys and girls. Available tissue specimens in three low ADC tumors demonstrated high-grade histology, whereas one high ADC tumor demonstrated low-grade histology with a histone H3.1 K27M mutation and high-grade metastatic lesion at autopsy. ADC derived from diffusion-weighted MRI may identify prognostically distinct subgroups of pediatric DIPG.\nView details for DOI 10.1007/s11060-014-1375-8\nView details for PubMedID 24522717", "pred_label": "__label__POS", "pred_score_pos": 0.8294270038604736}
{"content": "For those seeking to be politically engaged, the coronavirus pandemic poses significant issues. Across the country, local and state governments have created restrictions which bar large gatherings and discourage social interactions. With college campuses at their mercy, many universities have shut down for the fall semester. For those fortunate enough to remain on campus, engagement, especially that of a political nature, has been stifled. However, college students aren’t the only ones who face this issue. These troubles reach far past universities themselves, and deep into the communities in which these campuses reside.\nOlder populations are notorious for their political involvement. According to a 2019 study conducted by the Pew Research Center, 64% of eligible Baby Boomers voted in the 2018 midterms, while only 42% of eligible millennials and 30% of eligible Generation Z voters. This November, as many older voters stay home to remain safe, this will not only lower the number of voters at the polls, but the number of poll workers as well.\nIn another study conducted in 2020 by PRC, it was found that during the 2018 midterm, around six in ten poll workers were over the age of 61, and approximately 27% were over the age of 70. With citizens in this demographic being more likely to contract the novel coronavirus, poll worker shortages will be inevitable in the upcoming Nov. 3 election.\nHistory has shown that poll worker shortages are a direct cause of voter disenfranchisement, with effects ranging from long lines to complete poll closures. With many touting the 2020 election as one of the most important in recent history, and the growing doubt surrounding the use of mail-in voting, ensuring polling locations are adequately staffed is imperative.\nCampaigns such as Power The Polls, the Campus Compact Safe Elections Project, and the Campus Vote Project seek to make sure that voting as a form of civic engagement remains accessible to all. As students still on campus strategize ways which to both respect social distancing policies while also furthering their respective political causes, becoming a poll worker appears to be a strong option. In most places, poll workers are paid, which, along with protecting democracy, is a lucrative incentive for college students, who are usually low on money. Additionally, with many universities discussing the possibility of cancelling class on Election Day, being a poll worker is more accessible to students than ever.\nFor those seeking more information on how to become involved in their respective areas, visit Power The Polls for more information.", "pred_label": "__label__POS", "pred_score_pos": 0.5159564018249512}
{"content": "The anticipated impact of autonomous vehicles on driver safety\ncannot be overstated. According to federal data, roughly 37,000\npeople died and another 2.7 million were injured in car accidents\nin the United States in 2017 alone.\n1\nThe United States Department of Transportation estimates that\n94% of crashes involve driver-related factors, such as impaired\ndriving, speeding or illegal maneuvers.\n2 These striking\nnumbers are a driving force behind the enthusiasm for autonomous\nvehicles, which are expected to substantially diminish or eliminate\naccidents caused by human error.\nSuch a shift would not only improve safety, but also transform the litigation landscape. Most obviously, a substantial reduction in accidents would likely produce a correspondingly substantial reduction in accident-related litigation. But commentators have suggested that the character of the remaining litigation would also likely shift.\nIf human factors are largely eliminated from car accidents, the\nsupposition has been that liability for accidents would shift\nalmost entirely to car manufacturers, removing or severely\nrestricting the availability of comparative fault\ndefenses.\n3 Indeed, a number of automobile manufacturers\nhave previously stated that they would assume liability for\naccidents involving self-driving technology in their automobiles,\nwhile also noting that the anticipated liability for such accidents\nis likely to be very small or nonexistent, due to the safety\nimprovements that the technology is expected to\nconfer. 4\nThis approach also appears to reflect the assumption of\npotential regulators of autonomous vehicles. For example, in a\nwhite paper authored this month by the Governors Highway Safety\nAssociation — which is a nonprofit group that represents\nstate highway safety offices — a panel of experts\ncommissioned by the association noted that while some have\nsuggested that owners could remain liable for autonomous vehicles\ninvolved in accidents, \"[o]thers have suggested that the\n[autonomous vehicle's] manufacturer [would] be responsible\nunder product liability law.\"\n5\nIn reality, such statements — while broadly correct, in\nnoting that autonomous driving technology is likely to alter the\nshape of litigation — likely oversimplify things\nsignificantly. Already, what little litigation there has been over\nalleged defects in autonomous driving technology has involved\nallegations of fault by human parties to the accidents at issue, a\ntrend that is likely to continue at least during the likely long\ntransition period during which autonomous, semi-autonomous and\nnonautonomous vehicles coexist.\n6\nMoreover, even assuming there is a shift away from driver liability, it is not clear that liability will shift entirely to automobile manufacturers — especially in light of the trend toward outsourcing the multiple necessary components for an autonomous driving system to a diverse array of third-party vendors. Computerization of the driving function also opens potentially new frontiers for liability that were previously confined to other fields — such as hacking, which traditionally has threatened informational rather than physical harm.\nTo see the full article click here\nThe content of this article is intended to provide a general\nguide to the subject matter. Specialist advice should be sought\nabout your specific circumstances.", "pred_label": "__label__POS", "pred_score_pos": 0.9864563345909119}
{"content": "Neurotherapy utilizes the brains neuroplasticity, its ability to change, to guide the brain to a healthier functioning state. This is a lifelong ability.\nNEUROFEEDBACK\nTo understand how the brain is functioning, a brainmap, called a Quantitative EEG (QEEG) is analyzed, so the best brain training approach and protocols can be selected. Neurofeedback has been around for over 50 years and with the explosion of neuroscience research, significant advances have been made in the past decade.\nWe utilize state of the art neurotherapy approaches including Infra Slow Fluctuation, S-Loreta, Z-Score, HEG and LENS, utilizing Brainmaster technology. Unlike older methods that might require 20-40 sessions for evidence of change, these newer approaches demonstrate results quickly.\nA typical neurofeedback session entails having 3 sensors applied to the scalp and watching a video. The computer system analyzes brain activity and provides visual and auditory feedback, which the brain utilizes to improve its' self regulation.\nThe human brain is truly amazing. It grows and changes with consistent, repetitious stimulation. While it may be hard to believe that something that looks so simple can produce such significant change, it really does, to the delight of clients, every single day...", "pred_label": "__label__POS", "pred_score_pos": 0.777003824710846}
{"content": "Are you worried about an adult?\nPlease call\n0344 800 8020\nThis briefing from NHS Providers is based on extensive interviews with the leaders of\nseven trusts in the NHS providing good or outstanding care to people with a learning disability and people with autism, and broader ongoing engagement with trusts providing these services.\nThe report sets out in detail the\ncommon themes behind high-quality care, offering detailed case studies of how these services have succeeded.", "pred_label": "__label__POS", "pred_score_pos": 0.8247122168540955}
{"content": "The journal of the Genome engineering is devoted to rapid publications of full length research papers that lead to significant contribution in advancing knowledge in genome engineering. It promotes rigorous research that makes a significant contribution. Currently many journals primary objective is to encourage and assist the development of better and faster measures of Genome engineering. In cases where the scientific community believe they could contribute directly, as opposed to through highlighting the work of others, some of the journals are producing their own measures of research activity. work is mainly of interest to investors, organizations and individuals in the financial sector and to significant corporations with global operations, as well as governments and academic researchers.\nLast date updated on\nDecember, 2020", "pred_label": "__label__POS", "pred_score_pos": 0.6873254179954529}
{"content": "Development and the Brain: Ages, Stages, and the Neuroscience of Youth Development SKU:\nUnderstanding the ages and stages of child and youth development helps to design effective programs, navigate behavior management, and have a stronger impact. This session will explore the latest research from neuroscience and child behavior to understand each stage of childhood and adolescence.\nThis session is a 2-hour workshop. For 3 hours, the fee is $1,150, and for 5 hours, the fee is $1400. You will receive follow-up materials to support adoption of practices, and you can request further assistance after the session if needed.\nAudience: All staff who work with children and youth or who lead/design youth programs\nWant a customized version of this learning module? Just contact us!\n*Pricing is for NYC, Long Island, and Westchester. If outside of this metro area, additional travel fees may apply.", "pred_label": "__label__POS", "pred_score_pos": 0.6623645424842834}
{"content": "Titre : Performances of highland sheep under community-based breeding program in Atsbi Wenberta District, Tigray, Ethiopia Auteur : Regassa, M. Université de soutenance : Bahir Dar University. Grade : MSc thesis in Animal Breeding and Genetics. 2018 Résumé partiel This study was conducted in three PAs namely Habes, Golgolnealea and Gebrekidan of Atsbi Wenberta district of Tigray Region, Ethiopia, aimed at evaluating productive and reproductive performances of Highland sheep under on-going community-based breeding program (CBBP). The study also assessed existing sheep production system, major challenges and opportunities, farmers’ perception about the breeding program, its importance and the perceived impacts of the program, opportunities and challenges faced in running the program. Both quantitative and qualitative data were generated from primary and secondary sources. For the survey work a total of 195 household were randomly selected and interviewed using pre-tested, structured questionnaire. For the performance study, a total of 892 births, 817 weaning, 751 six months, and 564 yearling weight records and for reproductive performance evaluation a total of 464 age at first lambing, 381 lambing interval and 461 liter size records were used for the analysis. Additional data was collected during the study period (monitoring data) from randomly selected flocks in CBBP and non-CBBP households Growth performances, reflected in both birth and weaning weights, of Highland sheep under CBBP showed an improvement. Birth weight of progeny of selected rams was found significantly heavier than base flocks (2.39± 0.14kg vs. 2.02±0.21 kg ; p<0.01). Similarly, three month weight had shown highly significant variation between the two groups (8.98 ± 0.24 kg vs. 8.51± 0.38 ; p<0.01). However, this difference became insignificant at six month and yearly weight (p>0.05). This variation might indicate body weight improvements were accumulated due to effects of selection of rams in two rounds. In the current study, type of management, parity, sex of lambs, birth type, birth season and year were found significant sources of variation for both birth and three month weights. However, six month and yearling weights were affected by sex of lambs and birth season only (p<0.05). The overall mean reproductive performance in terms age at first lambing, lambing interval and liter size were 494±37.31days, 266.7±11.07days and1.12 ±0.15, respectively. Type of management was not found a significant source of variation (p>0.05). However, type of birth, parity and season of birth had significantly influenced AFL, LI and LS .Findings of the study indicated that the breed can produce three lambings in two years.\nPage publiée le 21 avril 2020", "pred_label": "__label__POS", "pred_score_pos": 0.5056359767913818}
{"content": "Minnesota voters now have seven days to submit their absentee ballot in advance of the 2020 general election on November 3, 2020. For the past several presidential elections Minnesota has led the nation in voter participation, and nothing is likely to change in 2020. Moreover, residents of our state have really taken to early voting. As the Minneapolis Star Tribune reports, “No-excuse absentee voting has been available in Minnesota since 2014 and has become an increasingly popular option with every passing election, but this one is likely to take the cake.”\nTo date, nearly 1.8 million absentee ballots have been requested and approximately 1.2 million of those have already been submitted and accepted by election officials across Minnesota. This represents a 375% increase in the total number of early ballots accepted in the general election of 2016 and the 2018 midterm elections.\nFor information on ways to vote early, including how to request, complete, submit, and track your absentee ballot, please visit the Office of the Secretary of State Elections and Voting webpage. This dedicated page also provides comprehensive details on how to register and vote safely on election day.\nYour voice matters. VOTE!", "pred_label": "__label__POS", "pred_score_pos": 0.6676281690597534}
{"content": "Abstract:\nBACKGROUND: There are limited empirical data available regarding the relationship between concussion history and neurocognitive functioning in active National Football League (NFL) players in general and NFL draft picks in particular. Potential NFL draft picks undergo 2 neurocognitive tests at the National Invitational Camp (Scouting Combine) every year: the Wonderlic and, since 2011, the Immediate Post-concussion Assessment and Cognitive Testing (ImPACT). After conclusion of the combine and before the draft, NFL teams invite potential draft picks to their headquarters for individual visits where further assessment may occur. PURPOSE: To examine the relationship between concussion history and neurocognitive performance (ImPACT and Wonderlic) in a sample of elite NFL draft picks. STUDY DESIGN: Cohort study; Level of evidence, 3. METHODS: Over 7 years, 226 potential draft picks were invited to visit a specific NFL team’s headquarters after the combine. The athletes were divided into 3 groups based on self-reported concussion history: no prior concussions, 1 prior concussion, and 2 or more prior concussions. Neurocognitive measures of interest included Wonderlic scores (provided by the NFL team) and ImPACT composite scores (administered either at the combine or during a visit to the team headquarters). The relationship between concussion history and neurocognitive scores was assessed, as were the relationships among the 2 neurocognitive tests. RESULTS: Concussion history had no relationship to neurocognitive performance on either the Wonderlic or ImPACT. CONCLUSION: Concussion history did not affect performance on either neurocognitive test, suggesting that for this cohort, a history of concussion may not have adverse effects on neurocognitive functioning as measured by these 2 tests. This study reveals no correlation between concussion history and neurocognitive test scores (ImPACT, Wonderlic) in soon-to-be active NFL athletes.", "pred_label": "__label__POS", "pred_score_pos": 0.612560510635376}
{"content": "Real-time alerts and monitoring save time, money and reduce waste\nPrecision farming requires farmers to adapt to a new technology-driven practice which demands collecting, managing and analysing data to make informed decisions quickly.\nGlasCore now makes this easier by allowing you to monitor various aspects of your business in real-time with automated alerts. You can build your own bespoke alerts and set specific alert ranges, so you’ll get a notification as soon as an issue is recognised. Get in touch to mitigate small issues before they become big costs.", "pred_label": "__label__POS", "pred_score_pos": 0.6799946427345276}
{"content": "The INCLUDE special report ‘To graduate or not to graduate?’ features Cape Verde’s graduation from LDC status in 2007. This report draws valuable lessons for other potentially graduating LDCs. It also discusses dependence on foreign aid and suggests new modes of international cooperation to ensure greater independence from aid.\nGraduation from least developed country (LDC) status is an issue of extreme relevance for development practitioners, donors, and potentially graduating countries. While graduation is generally positive and reflects inclusive growth, it comes at a cost. Graduated countries are no longer eligible for special treatment, including trade preferences and Official Development Assistance, and can be left in a vulnerable position if local or global conditions change. The Istanbul Declaration and Programme of Action aims at halving the number of LDCs by 2020, which is clearly an immense task.\nThis special report is based on a seminar conducted as part of the seminar series on ‘New Modes of Development Cooperation’ co-organized by INCLUDE and the Institute of Social Studies of Erasmus University.\nContributors are:\nDr Djalita Fialho, Pedro Pires Institute, Cape Verde Niels Hermes, Professor of Management and Finance, Faculty of Economics and Business, Groningen University Maria de Jesus Veiga Miranda, Deputy Minister of Foreign Affairs, Cape Verde Dr Corsino Tolentino, former Minister of Education and Director of the Gulbenkian Foundation, Cape Verde Marten van den Berg, MA, Director General International Economic Relations, Ministry of Foreign Affairs, the Netherlands Peter AG van Bergeijk, Professor of International Economics and Macroeconomics, Institute of Social Studies, Erasmus University and INCLUDE Knowledge Manager Rolph van der Hoeven, Emeritus Professor of the Institute of Social Studies, Erasmus University, and Member of the INCLUDE platform\nVideo impression of the seminar:", "pred_label": "__label__POS", "pred_score_pos": 0.6165124177932739}
{"content": "The global\nbody scrub market size is expected to reach USD 18.9 billion by 2025, according to a new report by Grand View Research, Inc., registering a 5.1% CAGR over the forecast period. Growing awareness regarding skincare and the desire to have younger looking and healthier skin are expected to drive the market. Body scrubs, or exfoliants, have several benefits; they eliminate dead skin cells and dirt, cleanse and rejuvenate the skin, and increase blood circulation. These advantages have upped their usage and demand among consumers.\nAnother factor driving product uptake is increasing number of working women in developing countries such as China, India, and Brazil. A surge in disposable income has resulted in growing spending on bath and beauty products, including body scrubs. This factor is anticipated to fuel the market over the forecast period. Use of essential oils in scrubs, such as coconut oil or olive oil, helps in maintaining skin moisture and protects the skin from different allergies. This feature also drives product demand.\nAsia Pacific dominates the global body scrub market and is expected to reach USD 6.6 billion by 2025. This revenue growth is attributed to high awareness regarding skincare among consumers and rapidly increasing population in countries like China and India. These countries have been attracting more players to invest in R&D so as to meet growing demands and requirements of people with various skin types.\nNorth America is expected to be the fastest growing market, exhibiting a CAGR of 5.6% from 2019 to 2025. This region is expected to witness steady growth in light of higher spending power and rising awareness about healthier and younger-looking skin, especially in U.S. Furthermore, strong brand goodwill and foothold of major industry players, including Soapworks Santa Cruz and Home & Body Co., through their well-established distributor networks in the region is projected to remain a favorable trend.\nPlant-based scrubs accounted for 46.8% of the overall market in 2018 owing to the many benefits they provide, resulting in a significant shift in consumer preference. An increasing number of salons and skin treatment centers globally have upped their usage and demand for these product variants to treat different skin problems.\nThe milk-based segment is also expected to witness rapid growth owing to increasing popularity of these product variants. They offer various benefits such as skin whitening and lightening, anti-aging, and treating sunburns. These products also have anti-inflammatory properties.\nClick the link below: https://www.grandviewresearch.com/industry-analysis/body-scrub-market Further key findings from the report suggest: The plant-based segment is expected to value USD 9.1 billion by 2025, fueled by growing uptake of these products across salons and skin treatment centers The online distribution channel is expected to register the highest CAGR of 6.0% over the forecast period owing to a thriving e-commerce industry and easy availability of a wide range of products Europe is expected to account for a share of 21.04% by 2025. Consumers in countries likeFrance, Germany, U.K., and Spain prefer using body scrubs instead of regular soaps to exfoliate and rejuvenate the skin Key industry players in this body scrub market include The Body Shop; Shieshdo; 3Lab Inc.; The Face Shop; Tonymoly Co. Ltd.; L’Oreal; The Forest Essentials; Sephora Inc.; and Innisfree Corporation.", "pred_label": "__label__POS", "pred_score_pos": 0.516172468662262}
{"content": "During a 20 day period of high fiber consumption in the form of bread made partly from wheaten wholemeal, two men developed negative balances of calcium, magnesium, zinc and phosphorus due to increased fecal excretion of each element. The fecal losses correlated closely with fecal dry matter and phosphorus. Fecal dry matter, in turn, was directly proportional to fecal fiber excretion. Balances of nitrogen remained positive. Mineral elements were well-utilized by the same subjects during a 20-day period of white bread consumption.", "pred_label": "__label__POS", "pred_score_pos": 0.7931514978408813}
{"content": "Superhydrophobic surfaces exhibit large contact angle and small hysteresis which promote liquid transport and enhance heat transfer. Here, liquid-vapor phase change behavior is reported on superhydrophobic surfaces with short carbon nanotubes deposited on micromachined posts, a two-tier texture mimicking the surface structure of lotus leaves. Compared to one-tier microtexture which energetically favors the Wenzel state, the two-tier texture with nanoscale roughness favors the Cassie state, the desired superhydrophobic state. During droplet evaporation, the two-tier texture delays the transition from Cassie to Wenzel state. Using two-tier texture with hexadeconethiol coating, continuous dropwise condensation was demonstrated for the first time on engineered superhydrophobic surfaces.", "pred_label": "__label__POS", "pred_score_pos": 0.6943601369857788}
{"content": "Updated: May 2019\nA car is generally considered totaled when the cost to repair the car exceeds the value of the car. Some states have laws that define a totaled vehicle by specific thresholds. In Alabama, for instance, a car may be totaled when the damage is greater than 75 percent of its value. In that case, if a vehicle is worth $5,000 and the repair estimate is $4,000, the vehicle would likely be considered totaled.\nIn other cases, the insurer determines whether a vehicle is considered a total loss.\nComprehensive coverage and collision coverage help pay to replace a totaled vehicle. These two separate coverages are typically required on your car insurance policy if you're leasing or financing your vehicle. If your car is paid off, they're optional. But, if your vehicle is totaled and you don't have comprehensive or collision coverage, you may have to pay out of pocket to buy a replacement vehicle.\nQuality Auto Coverage Starts Here.\nWhen you drive with quality coverage, you drive with peace of mind. Allstate auto insurance can help you stay protected for wherever the road takes you.\nGet a quote\nFind an agent\nIf you're involved in a car accident, there are a few basic steps to follow before and after your vehicle is considered totaled:\nContact your agent and initiate an insurance claim.\nYour insurer will determine whether the vehicle is a total loss, based on repair costs.\nYour insurer will issue payment for the actual cash value of the totaled vehicle, minus your deductible on your comprehensive or collision coverage.\nTo determine your car's worth (the \"actual cash value\" in insurance terms) at the time of the accident, insurers typically use a number of factors to figure your car's actual cash value, including its age, condition, mileage and resale value, in addition to the selling price of similar vehicles in your area..\nIf you're financing a car that's been totaled, your insurance company will likely make the claim check payable to both you and your lender, which means you'll have to come to an agreement with your lender on how to release that money, the Insurance Information Institute (III) says. Typically, the lender will be reimbursed first, with any remaining money then being paid to you.\nIt's possible that you may still owe your lender more for the car than the insurance payment you receive. In that case, you are responsible for paying the remaining balance on the car lease or loan. For instance, suppose you owe $15,000 on your car loan, but your vehicle's value has depreciated to $13,000 when it's totaled. If you have collision coverage, your insurer would reimburse you for the actual cash value of your car — in this case, $13,000. You would have to pay your lender that amount, plus the remaining $2,000 out of your own pocket.\nAdding loan or lease gap coverage to your car insurance policy is one way to help protect against paying a lender out of pocket for a totaled vehicle. Depending on your insurer, this optional coverage may be available as part of a package or as a standalone coverage. It may also be available only for brand-new cars\nIn some cases, a totaled car may not be anyone's fault. Suppose, for instance, that a tree topples onto your parked car and your insurer declares it's totaled. If you have comprehensive coverage on your car insurance policy, it will likely reimburse you for the actual cash value of your vehicle (again, minus your deductible).\nIf your car is totaled in an accident that is caused by another driver, your collision coverage may first come into play. However, your insurer may seek repayment from the other driver's insurer to cover the loss. In some cases, that may mean you are also reimbursed for the deductible that was subtracted from your insurance payout.\nIf your vehicle's airbags deploy in a car accident, that does not necessarily mean your car is a total loss. Your insurance adjuster will assess the situation and determine if the cost of replacing the airbags and repairing your vehicle would exceed its actual cash value. If the cost of repairs is less than the value of your car, your vehicle will likely not be declared a total loss.\nHave more questions about car insurance coverages or a totaled vehicle? Talk to a local agent.", "pred_label": "__label__POS", "pred_score_pos": 0.6857465505599976}
{"content": "Key features A sustainable concept\nThe Jazia PVS concept is described under the bilateral governmental agreement between the governments of Tanzania and Switzerland, signed by MoHCDGEC and PO-RALG.\nThe Jazia PVS system was conceptualized and designed in a fully transparent and participatory approach involving regional, district and health facility stakeholders.\nThe Jazia PVS is sustainable as it is not a parallel system. It is built basing on existing government policies and guidelines and operates within the regional government structure.\nA supplementary source to MSD and a safety net\nThe Jazia PVS serves as a safety net to the region in case of stock rupture at MSD and/or an unexpected spike in demand without compromising quality or price.\nThe Jazia PVS does not replace MSD but serves as a supplementary source for medicines and supplies out of stock or short supplied or not stocked by MSD.\nThe contracted Prime Vendor maintains sufficient stock level to meet supply shortfalls experienced from MSD.\nFixed costs and fiscal decentralization\nThe system does not utilize conventional source of funding e.g. funds deposited by the government at MSD for health facilities, but utilizes supplementary sources of funds such as user/cost sharing fees, CHF, NHIF and basket funds.\nDistricts pool their demand for supplementary medicines at the regional level, benefitting from uniform prices in all districts.\nThe PV system allows health facilities through Health Facility Governing Committees (HFGCs) to manage own funds following stringent SOPs hence enhancing fiscal decentralization. This is in line with the government policy of empowering health facilities to respond to community needs.\nDelivery of quality medicines\nThe system supplies essential medicines and supplies of assured quality, safety and efficacy in accordance with the MoHCDGEC National Essential Medicines List and national oversight by the TFDA.\nThe system initially delivers to district headquarters; with option in the future to deliver directly to health facilities.\nPublic health facilities in the region have gained new options for improving drug availability without compromising quality or price.\nCoordination, monitoring and expansion\nThe region operates a Jazia PVS office represented by a PV coordinator, a dedicated pharmacist and support staff to coordinate and monitor the performance of the system.\nThe system is closely managed and supported by mandated administrative structures such as a technical committee and a tender board appointed by the regional authorities.\nThe Jazia PVS was successfully piloted in Dodoma region and expanded to Morogoro and Shinyanga regions.\nScale-up to all regions of mainland Tanzania was decided by the PO-RALG.\nTechnical support is provided by the Health System Strengthening Resource Centre (HSS-RC) at PO-RALG.", "pred_label": "__label__POS", "pred_score_pos": 0.7616814374923706}
{"content": "Business Cycle Dating Committee Announcement June 8, 2020\nDetermination of the February 2020 Peak in US Economic Activity\nCambridge, June 8, 2020 - The Business Cycle Dating Committee of the National Bureau of Economic Research maintains a chronology of the peaks and troughs of US business cycles. The committee has determined that a peak in monthly economic activity occurred in the US economy in February 2020. The peak marks the end of the expansion that began in June 2009 and the beginning of a recession. The expansion lasted 128 months, the longest in the history of US business cycles dating back to 1854. The previous record was held by the business expansion that lasted for 120 months from March 1991 to March 2001. (This report is also available as a pdf.)\nThe committee also determined that a peak in quarterly economic activity occurred in 2019Q4. Note that the monthly peak (February 2020) occurred in a different quarter (2020Q1) than the quarterly peak. The committee determined these peak dates in accord with its long-standing policy of identifying the months and quarters of peak activity separately, without requiring that the monthly peak lie in the same quarter as the quarterly peak. Further comments on the difference between the quarterly and monthly dates are provided below.\nA recession is a significant decline in economic activity spread across the economy, normally visible in production, employment, and other indicators. A recession begins when the economy reaches a peak of economic activity and ends when the economy reaches its trough. Between trough and peak, the economy is in an expansion.\nBecause a recession is a broad contraction of the economy, not confined to one sector, the committee emphasizes economy-wide indicators of economic activity. The committee believes that domestic production and employment are the primary conceptual measures of economic activity.\nThe Month of the Peak\nIn determining the date of the monthly peak, the committee considers a number of indicators of employment and production. The committee normally views the payroll employment measure, which is based on a large survey of employers, as the most reliable comprehensive estimate of employment. This series reached a clear peak in February. The committee recognized that this survey was affected by special circumstances associated with the pandemic of early 2020. In the survey, individuals who are paid but not at work are counted as employed, even though they are not in fact working or producing. Workers on paid furlough, who became more numerous during the pandemic, thus resulted in an overcount of people working in recent months. Accordingly, the committee also considered the employment measure from the Bureau of Labor Statistics household survey, which excludes individuals who are paid but on furlough. This series plateaued from December 2019 through February 2020, and then fell steeply from February to March. Because both series measure employment during the week or pay period containing the 12th of the month, they understate the collapse of employment during the second half of March, as indicated by unprecedented levels of new claims for unemployment insurance. The committee concluded that both employment series were thus consistent with a business cycle peak in February.\nThe committee believes that the two most reliable comprehensive estimates of aggregate production are the quarterly estimates of real Gross Domestic Product (GDP) and of real Gross Domestic Income (GDI), both produced by the Bureau of Economic Analysis (BEA). These measures estimate production that occurred over an entire quarter and are not available monthly. The most comprehensive monthly measure of aggregate expenditures, which includes roughly 70 percent of real GDP, is monthly real personal consumption expenditures (PCE), published by the BEA. This series reached a clear peak in February 2020. The most comprehensive monthly measure of aggregate real income is real personal income less transfers, from the BEA. The deduction of transfers is necessary because transfers are included in personal income but do not arise from production. This measure also reached a well-defined peak in February 2020.\nThe Quarter of the Peak\nIn dating the quarterly peak, the committee relies on real GDP and real GDI as published by the BEA, and on quarterly averages of key monthly indicators. Quarterly real GDP and real GDI peaked in 2019Q4.\nThe quarterly average of employment as measured by the payroll series rose from 2019Q4 to 2020Q1. However, the committee concluded that the special factor noted above implies that the series should not play a significant role in determining the quarterly peak. The quarterly average as measured by the household survey reached a clear peak in 2019Q4. The committee concluded that like GDP and GDI, the number of people working also reached its quarterly peak in 2019Q4.\nThe fact that the monthly peak of February occurred in the middle of 2020Q1 while the quarterly peak occurred in 2019Q4 reflects the unusual nature of this recession. The economy contracted so sharply in March (the final month of the quarter) that in 2020Q1, GDP, GDI, and employment were significantly below their levels of 2019Q4.\nFurther Comments\nThe usual definition of a recession involves a decline in economic activity that lasts more than a few months. However, in deciding whether to identify a recession, the committee weighs the depth of the contraction, its duration, and whether economic activity declined broadly across the economy (the diffusion of the downturn). The committee recognizes that the pandemic and the public health response have resulted in a downturn with different characteristics and dynamics than prior recessions. Nonetheless, it concluded that the unprecedented magnitude of the decline in employment and production, and its broad reach across the entire economy, warrants the designation of this episode as a recession, even if it turns out to be briefer than earlier contractions.\nCommittee members participating in the decision were: Robert Hall, Stanford University (chair); Robert Gordon, Northwestern University; James Poterba, MIT and NBER President; Valerie Ramey, University of California, San Diego; Christina Romer, University of California, Berkeley; David Romer, University of California, Berkeley; James Stock, Harvard University; Mark Watson, Princeton University.", "pred_label": "__label__POS", "pred_score_pos": 0.9148219227790833}
{"content": "Nevada OSHA Provides Additional Requirements for Construction Employers to Address Feasibility of Social Distancing at Construction Sites\nWhen Nevada’s Governor identified construction as an essential business amid the initial directives of the COVID-19 state of emergency, the executive order required construction employers to “maintain strict social distancing practices to facilitate a minimum of six feet of separation between workers.” Now, nearly a month later, Nevada’s Occupational Safety and Health Administration has recognized that strict social distancing measures are not always practical or feasible among workers on an active construction site. On April 20, 2020, Nevada OSHA issued revised guidelines addressing ongoing construction activity when social distancing cannot practically be maintained.\nThe guidelines continue to emphasize that safety and training meetings, tailgate talks, and similar gatherings must be restricted to 10 people or less. Additionally, the employer remains responsible for monitoring employees on lunch breaks, slack periods and in employee parking areas to ensure compliance with social distancing protocols.\nYesterday’s revisions to the guidelines, however, recognize that maintaining six feet of social distancing among employees is often neither practical nor feasible during active construction work. In such circumstances, the construction employer is now required to implement the following measures:\nComplete a “Job Hazard Analysis” (JHA) for each task, procedure or instance where social distancing is infeasible. Each JHA must be of equivalent detail and scope as identified in Federal OSHA publication 3071. Each JHA completed for this purpose must specifically identify the task being addressed, hazard being addressed (spread of COVID-19), and controls used to address the hazard. Any policy or procedure identified in the JHA to address the hazard must be at least as effective, or more effective, than six feet of social distancing. Engineering controls, administrative controls, and/or Personal Protective Equipment (PPE) required to implement the policy or procedure identified in the JHA must be provided by the employer. The employer must provide comprehensive training to all impacted staff for the implementation of the policy or procedure identified in the JHA, along with training for use of any and all equipment and PPE necessary for its implementation.\nNevada OSHA is implementing random construction site inspections to monitor compliance with all COVID-19 mandates, including the revised guidelines regarding the JHA procedures. Failure of an employer to observe the guidelines could result in OSHA administrative penalties up to and including site closure in extreme cases.\nNewmeyer Dillion is tracking these trends and issues to counsel our clients whose businesses are at stake during these unprecedented circumstances. Please reach out to our COVID-19", "pred_label": "__label__POS", "pred_score_pos": 0.7884365320205688}
{"content": "Frontline caregivers across the United States—and in many other countries, no doubt—are bombarded by multiple quality improvement (QI) projects. A clinical unit might simultaneously be engaged in efforts to reduce readmissions, eliminate hospital-acquired infections and other complications, increase hand-hygiene compliance, improve performance on core measures, and enhance the patient experience. The demands brought by participating […]", "pred_label": "__label__POS", "pred_score_pos": 0.7794996500015259}
{"content": "Clean surfaces of the bath, basin and shower trays regularly. Rinse thoroughly with running water to prevent build-up of mildew.\nKeep the shower door/curtain open and ventilate the room after use.\nTo remove soap residue and prevent build-up of lime stains, clean the bathroom surfaces regularly.\nLaunder towels, facecloths and bathmats regularly to remove bacteria of skin or faecal origin and fungi.\nIf the shower has not been used for a while, run hot water for 2-3 minutes to flush out any harmful microbes.\nYou can save water by taking a shower instead of a bath.\nIf someone at home has an infection, clean and disinfect taps and door handles often.\nIf someone has a skin or nail infection, clean bathroom surfaces more frequently and then use a disinfectant.\nDo not share towels with other family members.\nLegionnaires bacillus in the showerhead can be a risk to people with reduced immunity, if they inhale infected water droplets whilst showering.\nPotentially harmful microbes from skin, nail and oral infections (e.g. athletes’ foot) can spread to others on surfaces, towels and toothbrushes.\nA key moment for hygiene is touching surfaces frequently touched by others.\nInstall a water-saving shower head and tap nozzle and don’t leave the tap running while brushing your teeth.", "pred_label": "__label__POS", "pred_score_pos": 0.7879923582077026}
{"content": "The subject of ‘population’ is undergoing a renaissance in geography; this is seen, for example, in the voluminous studies addressing ‘marginalized’ populations, including but not limited to refugees, internally displaced persons, and children. In short, scholarship has focused on those lives rendered ‘wasted’, ‘precarious’, or ‘superfluous’. Population geographers have made substantial contributions; however, more can be done. In this and the next two progress reports, I suggest that population geographers reflect more deeply on the spatiality and survivability of vulnerable populations. More specifically, population geographers should consider the politics of fertility, mortality, and mobility from the standpoint of a layered demographic question: within any given place, who lives, who dies, and who decides? In this first report, I resituate the concept ‘surplus population’ within the broader domain of population geography. In subsequent reports, I consider more closely population geography’s association with related subject areas (i.e. biopolitics and necropolitics). I maintain that, by addressing vulnerability and survivability, we join others in geography and allied fields who are writing about ‘populations’ not as biological, pre-given entities, but instead as political subjects at risk of premature death.", "pred_label": "__label__POS", "pred_score_pos": 0.7714427709579468}
{"content": "Abstract\nFor a given invasive plant species and control method, effective invasive plant eradication requires regular monitoring and management. While most previous studies characterize invasive plant species, develop appropriate control methods, or prioritize species for management using aggressiveness and other considerations, few study why some forestland owners are less likely than others to regularly remove invasive plant species. Such information is useful in prioritizing and targeting forestland owners who are at greater risk for invasion, with the stands threatening adjacent forestlands. Towards this end, we surveyed 1800 forestland owners in Virginia and Texas. We use data on forestland owners' socioeconomics and forestland features-such as acreage, forestland ownership objectives, and forest management activities-to determine how these factors affect the regularity of invasive-plant removal. For these purposes, we used the Cochran-Armitage trend test, the Cochran-Mantel-Haenszal regression, odds ratio estimates, and partition-analysis techniques. Our results suggest that female forestland owners, owners with smaller forestlands, and forestland owners without written forest-management plans are less likely than others to regularly remove invasive plant species. Forest-management activities, such as building/maintaining roads in the forestland, partially harvesting stands, and wildlife- and fisheries-improvement projects, also significantly predict a more regular invasive-plant-removal tendency. However, since these activities are potential pathways for the spread of invasive plant species, we controlled for the other significant covariates and measured the relationship between frequent practice of the given forest-management activities and having a tendency to regularly remove invasive plant species. The results suggest that forestland owners that regularly practiced the said forest-management activities have higher odds for tending to remove invasive plant species regularly, suggesting that, despite their demonstrated effort at removing invasive plant species from their forest, their management activities may be inadvertently contributing to the spread of invasive plant species. These results highlight the importance of integrating invasive-plant-removal plans with forest-management plans as well as forestland owners' educational and outreach needs.\nKeywords Control methods Forestland owners Invasive plants Management practices", "pred_label": "__label__POS", "pred_score_pos": 0.6065406799316406}
{"content": "Questioning strategies and critical thinking\nA scrutiny numerous professors countenance is warranting cogent ways to buy students in meaningful tete-a-tete that advances thinking and enucleates ticklish, higher-order responses installed on ordinary literature needs.\nThe scope of this assignment is to plan scrutinys that succor ticklish and higher-order thinking. To accomplished the assignment, you accomplish criticize misapply scrutiny-asking methods for gradation and ability rolls.\nSelect an primary gradation roll and warrant aligning social or recite English discourse arts standards. Warrant at meanest 1-2 standards that you can blend into a realistic scrutiny and vindication tete-a-tete betwixt you (the professor) and one or past students. In 500-750 control, the tete-a-tete should include:\nA nucleus on a question or ardor akin to balbutiation or communication a gradation-roll scholarly or informational quotation (e.g., discussing a warner quotation, discussing the structures of quotations, brainstorming during a communication workshop conference, etc.) At meanest three gradation-roll misapply scrutinys that enucleate higher-order and ticklish thinking amid the full area\nIn an additional 100-250 control, catalogue the standards separated and elucidate how the tete-a-tete teaches the skills pictorial in the standards.\nSubmit your tete-a-tete and meditation as one deliverable.\nAPA phraseology is not required, but strong academic communication is expected.", "pred_label": "__label__POS", "pred_score_pos": 0.9601340293884277}
{"content": "Samarthaben J. Patel\nCredentials: B.Tech National Institute of Technology, Surat; M.S. Yale University\nPosition title: Graduate Student\nEmail: spatel46@wisc.edu\nPhone: she/her/hers\nAddress:\nRoom 2029, 1415 Engineering Drive, Madison, WI 53706 ABOUT ME\nSamartha Patel is from Surat, Gujarat, India. She completed her Bachelor of Technology in Chemical Engineering with a gold medal for outstanding academic performance in 2015. After completing her undergraduate degree, she earned a Master of Science in Chemical and Environmental Engineering from Yale University. Samartha joined the Van Lehn group in Fall 2016. In her free time, she likes to do oil painting, and sailing and winter kiting on Lake Mendota.\nRESEARCH INTEREST\nA significant challenge in designing drug and gene delivery agents is to understand how they interact with lipid bilayers which is the major component of the cell membrane. The self-assemblies of these amphiphilic biomolecules can affect a variety of interfacial properties and dictate their transport across the cell membrane. My research focuses on developing and applying multiscale simulations and enhanced sampling techniques to understand the molecular mechanisms of how the structure of biomolecules affect their self-assemble, interaction with other biomolecules and also their transport pathways across the cell membrane. The insights obtained from these molecular simulations would have potential applications in designing drug delivery agents and co-assembled structures of their synthetic mimics which can efficiently translocate across the cell membrane.\nPUBLICATIONS\n2. C. G. Gahan*, S. J. Patel*, M. E. Boursier, K. E. Nyffeler, J. Jennings, N. L. Abbott, H. E. Blackwell, R. C. Van Lehn, D. M. Lynn. “Gram-negative bacterial quorum sensing signals self-assemble in aqueous media to form micelles and vesicles: an integrated experimental and molecular dynamics study.”\nJournal of Physical Chemistry B 2020, 124 (18), 3616-3628. [Link]\n1. S. J. Patel and R. C. Van Lehn. “Characterizing the Molecular Mechanisms for Flipping Charged Peptide Flanking Loops across a Lipid Bilayer.”\nThe Journal of Physical Chemistry B 2018, 122(45), 10337-10348. [Link]", "pred_label": "__label__POS", "pred_score_pos": 0.8533161282539368}
{"content": "Our brains are pretty amazing, but they can make a lot of mistakes that we are not even aware of. Sometimes these may have negative long-term consequences, but often they just mean a moment of misunderstanding or confusion. Here are 5 common mistakes your brain makes every day! We trust our memories, even though they…", "pred_label": "__label__POS", "pred_score_pos": 0.9001483917236328}
{"content": "Foros:\nCyclotron Road is a fellowship program that supports leading entrepreneurial scientists as they advance a project with the potential for global impact. Our goal is simple: empower innovators to mature their ideas from concept to first product, positioning them to align with the most suitable commercial path to bring their technology to scale.\nCyclotron Road fellows are embedded in the Berkeley research ecosystem for two years with an explicit mandate to bring their ideas to the point of commercial viability. As part of our Cohort, innovators receive:\nA two year fellowship—Rapid progress requires an “all-in” commitment. Our Cohort fellowship provides a living stipend and health insurance for two years so that innovators can be 100% focused on their projects. Unencumbered access to world-class research facilities and expertise—Hard tech innovation requires sophisticated infrastructure. As part of the program, Cohort innovators access facilities, equipment, and expertise at Berkeley Lab and UC Berkeley, and receive initial research funding to catalyze collaborations. Innovators own all intellectual property developed during the program. An intensive program of mentorship, education, and networking—Our curriculum is tailored to support the challenges of hard tech innovation. Participants receive intensive mentorship and education covering all aspects of the journey from concept to product. We also expose them to a wide range of leaders from academia, industry, government, and finance that can serve as advisors or partners.\nApplications for\nCyclotron Road Cohort Five are open until October 31, 2018. Please Click here to view a detailed timeline and our FAQs. Click the Apply button to start the application process. If you should have any additional questions, please contact Cedricka Harris at DOE-RPP@orau.org.", "pred_label": "__label__POS", "pred_score_pos": 0.824311375617981}
{"content": "UK-based property market information provider Landmark Information announced today the launch of RiskHorizon, its new ESG management platform. The platform is designed to provide thorough and actionable global ESG due diligence of corporate investments and acquisitions to investors, property asset owners and managers and lawyers.\nLandmark is launching the new product after acquiring the RiskHorizon ESG due diligence platform from global sustainability consultancy Anthesis Group in October. With the launch, Landmark stated that its proposition now includes a self-service software platform with an intuitive toolkit to screen, diligence, score and manage investment performance.\nAccording to the firm, the RiskHorizon database spans 90 industries and more than 45 ESG risks in over 175 countries, assessing datasets from a host of authoritative sources including the World Bank, Unicef, the Global Child Forum, Freedom House, and United Nations Development Programme. Additionally, the platform has integrated the full breadth of the SASB (Sustainability Accounting Standards Board) Materiality Map to intelligently determine a wide range of relevant risks, by sector, including greenhouse gas emissions, biodiversity impacts, data security and customer privacy, diversity and inclusion, and bribery and corruption, among others.\nSimon Boyle, Environmental Law Director of Landmark Information said:\n“With C-suite executives, investors, supply chain managers and risk managers increasingly required to screen against Environmental, Social and Governance criteria, RiskHorizon significantly contributes to improving the performance of companies as well as managing portfolios, irrespective of their sectors or geography.\n“Traditional environmental compliance is quickly evolving into the Environmental, Social and Governance space and those that do not engage with ESG will be left behind. With RiskHorizon, we provide the tools for risk management across law firms, private equity and corporate supply chains, enabling effective due diligence and ongoing ESG portfolio management.”", "pred_label": "__label__POS", "pred_score_pos": 0.5085046291351318}
{"content": "►▼Show Figures\nOver the last several decades, warming in the Arctic has outpaced the already impressive increases in global mean temperatures. The impact of these increases in temperature has been observed in a multitude of ecological changes in North American tundra including changes in vegetative cover, depth of active layer, and surface water extent. The low topographic relief and continuous permafrost create an ideal environment for the formation of small water bodies—a definitive feature of tundra surface. In this study, water bodies in Nunavut territory in northern Canada were mapped using a long-term record of remotely sensed observations at 30 m spatial resolution from the Landsat suite of instruments. The temporal trajectories of water extent between 1985 and 2015 were assessed. Over 675,000 water bodies have been identified over the 31-year study period with over 168,000 showing a significant (p\n< 0.05) trend in surface area. Approximately 55% of water bodies with a significant trend were increasing in size while the remaining 45% were decreasing in size. The overall net trend for water bodies with a significant trend is 0.009 ha year\n−1\nper water body.View Full-Text\nThis is an open access article distributed under the Creative Commons Attribution License\nwhich permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited", "pred_label": "__label__POS", "pred_score_pos": 0.9994422197341919}
{"content": "Beskrivelse\nA new report titled Possible elements of a new global agreement to prevent plastic pollution aims to develop global sustainability criteria for product design, providing the tools for governments to regulate national markets. Potential objectives and strategic goals are defined, a first structure for a potential new global agreement is outlined, and national implementation measures are identified to achieve the global goal of zero discharge of plastics into the environment. By addressing the issue at the design phase, all sources and pathways of marine plastic pollution can be addressed. Importantly, the existing weakness in the current framework on upstream and midstream activities of the plastics value chain can be addressed by providing robust national financial mechanisms that improve downstream activities in all countries.", "pred_label": "__label__POS", "pred_score_pos": 0.6369979381561279}
{"content": "How we use and dispose of our resources is crucial – in fact it accounts for 60% of our emissions. We must be more conscious of the impact we are having by the daily choices we make. Sustainable alternatives exist to disposable cups and the purpose is to shift behaviour towards the use of these alternatives.\nA targeted consultation is underway on the proposals, with key stakeholders such as those referred to in the question, in addition to a public consultation and it is open to all interested parties to have their say.\nI also held a forum on the future of Ireland’s waste on the 16th of September. At that forum, stakeholders from industry, local authorities, waste collectors, NGOs and regulators were invited to discuss how we can deliver on our ambitious targets. There were six breakout sessions on the day and one of the items discussed was a suggestion to examine levies as a policy tool to reach targets.\nFurthermore, in the context of raising awareness of Directive 2019/904 on the reduction of the impact of certain products on the environment - commonly referred to as the Single Use Plastic (SUP) Directive, my Department has engaged and continues to engage with a range of stakeholders. This Directive includes an obligation on all EU Member States to introduce measures to achieve an ambitious and sustained reduction in the amount of single use plastic cups for beverages.", "pred_label": "__label__POS", "pred_score_pos": 0.8597196936607361}
{"content": "Chemotherapy is the use of medication to kill cancer cells. It is used in advanced stages of uterine cancer. You can take chemotherapy either by mouth or have the medication injected. Because chemotherapy medication passes through your blood stream, it can treat cancer that has spread to multiple areas.\nContinue Learning about Endometrial (Uterine) Cancer\nImportant: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.", "pred_label": "__label__POS", "pred_score_pos": 0.9898488521575928}
{"content": "We were delighted to launch the new BGS website in September. If you have not already had an opportunity to visit it, please take a look.\nOn September 22 we were pleased to co-host with AHDB the second in a series of webinars on herbal leys. The panel discussion for the evening focused on establishment. Key messages from the evening were that a soil temperature of at least eight to 10C was critical to success, along with ensuring that a good fine seedbed was initially prepared, and the importance of rolling to achieve excellent seed to soil and moisture contact.\nFor a recording of the discussion please follow the link on the BGS website or visit the AHDB YouTube channel. The third webinar in the herbal ley series will be held on December 1 between 7pm and 8pm. Further details are also located on the website.\nThis is the last BGS column for 2020, following a very difficult year. The BGS team wish you a happy festive season and a healthy, prosperous 2021. We look forward to welcoming everyone back to BGS events next year.\nTom Goatman is the British Grassland Society chief executive.", "pred_label": "__label__POS", "pred_score_pos": 0.9573906064033508}
{"content": "Remember college classes? Sitting in a lectures taking notes? Remember how engaging these lectures were?\n\"Sage on the stage\" is how this method of instruction is known.\nIf you're like most people, a good portion of college lectures were terribly boring and did not fully engage you.\nFast forward to - now - you're a teamwork facilitator (coach, trainer, manager, educator, etc.). How often do you talk at your audience (lecture at them)?\nIf you to are applying the \"sage on the stage\" method of teaching then it's likely your audience is walking away from the experience with much less than you think.\nResearch shows that your students will learn more if they are actively (as in out of their chair) learning.\n\"According to the best-evidence synthesis, we found strong evidence of a significant positive relationship between physical activity and academic performance.\"\nLESSON: To be a more effective teamwork facilitator and fully engage your audience learn how to get people up and moving and learning at the same time.", "pred_label": "__label__POS", "pred_score_pos": 0.9993814826011658}
{"content": "The West Nipissing Assessment Centre is located at 219 O’Hara Street, Sturgeon Falls, ON P2B 2Y6. Please be advised that the Assessment Centre is located in the Marcel Noel Hall (upstairs) beside the Recreation Centre.\nAs of Tuesday, October 6, 2020, you will need an appointment to get a test at the Assessment Centre. Prior to booking your appointment, please:\nReview the eligibility information below; Determine if you require a COVID-19 test by completing a self-assessment; Do not seek testing at multiple assessment centres as this will result in delayed access and delayed test results for all. If you have already booked an appointment at an assessment centre and can no longer make it, please cancel and rebook your time so others who need a test can be seen.\nMonday: 10:00-4:00 PM\nTuesday: 10:00-4:00 PM Wednesday: 10:00-4:00 PM Thursday: 10:00-4:00 PM Friday: 10:00-4:00 PM\nAs per provincial directives, testing at the West Nipissing Assessment Centre will be\nby appointment only as of Wednesday, October 7, 2020.\nIf you are\nsymptomatic and require testing, please call (705) 580-2186 between 10:00 AM and 4:00 PM to make an appointment.\nBased on the\nOntario Government’s current COVID-19 testing guidelines, individuals meeting the criteria below are eligible to be assessed at the Assessment Centre: Individuals with symptoms of COVID-19* Direct contacts of confirmed COVID-19 cases** identified as: a household contact (note this does not include contacts of contacts such as a friend of someone if your household) Directed or recommended by public health via contact tracing or outbreak investigation Notified via the COVID Alert app.\nIn addition, the below groups are eligible for testing at the Assessment Centre regardless of the presence of symptoms:\nWorkers in long-term care homes every two weeks. Long-term care workers should not be tested than every two weeks unless directed by public health in an outbreak setting. Essential caregivers visiting long-term care homes. Residents or workers in homeless shelters or other congregate settings as outlined in guidance from the Ministry of Health. Pre-operative patients prior to receiving general anaesthesia and cancer patients receiving therapy as outlined by the Ministry of Health. International students who have passed their 14-day quarantine period, or who have developed symptoms within their 14-day period (breaking quarantine to get a test is not encouraged but the assessment centre will not turn symptomatic individuals away). Farm workers. Indigenous communities. Individuals who need testing for international travel clearance (note: this is an interim measure. Please check Ontario.ca/covidtest to ensure you have the most current information).\nThe list of people who are eligible for testing at assessment centres regardless of their symptoms may change from time to time. You should confirm your eligibility for a COVID-19 test with your healthcare provider before seeking testing.\n**If an asymptomatic close contact tests negative, they must remain in self-isolation for 14 days from their last exposure to the case. If they later become symptomatic within the isolation period, they should be retested.\nThe only exception is if the individual was alerted to a possible exposure by the COVID Alert app, then they must isolate until they receive their test results. If the results are negative, they are required to self-monitor for 14 days from when they received the alert. If they become symptomatic within the isolation period, they should be re-tested and self-isolate until they receive their test results.\nChildren are eligible for testing when they have the following symptoms:\nAre recommended for testing by the local public health unit. Are exhibiting new/worsening symptoms of: Fever and/or chills Cough Shortness of breath Decrease or loss of smell or taste Exhibiting two (2) or moreof the following new/worsening symptoms: Sore throat Runny/stuff nose Headache Nausea/Vomiting/Diarrhea Fatigue, lethargy, muscle aches or malaise. You must screen for COVID-19 every day before going to school/child care. Use the school screening tool to help make this decision.\nThe following are examples of individuals who do not meet testing eligibility criteria:\nAsymptomatic individuals seeking workplace testing outside of outbreak investigations or government requirements. Other members of the family that do not fit the current COVID-19 testing guidance (those without eligible symptoms or who are not a contact of a confirmed COVID-19 case). Asymptomatic close contacts of an individual with symptoms compatible with COVID-19, unless the individual is confirmed as COVID-19 infected. Asymptomatic contacts of case contacts (close contacts of an individual who is a contact of a confirmed case of COVID-19, unless the individual is confirmed as COVID-19 infected). Asymptomatic sports team member testing unless referred by public health.", "pred_label": "__label__POS", "pred_score_pos": 0.5321429967880249}
{"content": "Hello all,\nIn this update, I thought I’d finally disclose the findings of my research. While much remains unknown about mechanisms in the brain, certain systems— such as those that process opioids— have been explored in numerous contexts. Unfortunately, there is not enough evidence to conclusively determine whether the types of bonds drugs form in the brain influence their addictiveness. However, several studies allude to a potential correlation between drug addictiveness and intermolecular bonds in the brain. If further studies corroborate such a correlation, then our medical understanding of addiction could be greatly improved.", "pred_label": "__label__POS", "pred_score_pos": 0.9806563258171082}
{"content": "Young cancer patients should feel lucky to survive, and stop fussing about their prospects of having children. This attitude, though still widespread, is now being challenged by many patients and doctors, who argue that it is inexcusable to prescribe treatments that could render a patient infertile, without a thorough discussion of all the options.", "pred_label": "__label__POS", "pred_score_pos": 0.9901615381240845}
{"content": "Ordinarily, user profiling is conducted by formally surveying a statistically representative sample of the user population. Interviewing a few “expert informants” who are familiar with the needs and characteristics of a range of users can also provide valuable data in a fraction of the time needed for distributing and analyzing a survey instrument. However, “experts” on design teams occasionally hold mistaken beliefs about users, so the resulting user profiles may not be as reliable. Choosing the right approach for your organization should balance the costs of conducting a user profiling survey against the risks of developing a system based on false assumptions about the users.\nWe recommend profiling your user base even before you collect data about your target users’ work environments and tasks. Creating user profiles allows you to identify the categories of users who will be using the system most frequently or who may have high risk use cases, thus concentrating the most efficient allocation of your development resources. However, it’s a good idea to reassess your user profiles periodically, because demographic or economic shifts may alter the requirements of your user population.\nAssistance from an experienced researcher will help ensure that the user profile data you collect will be accurate, objective, and relevant to your project, whether by aiding you with the design, administration, or analysis of a user profiling questionnaire, or by conducting interviews with user representatives.", "pred_label": "__label__POS", "pred_score_pos": 0.6114836931228638}
{"content": "Traders Lose $805 million Following Bitcoin Flash Crash\nBitcoin’s rise in the past few weeks has been an exciting ride for traders and investors who have been able to rack in profits. However, the recent developments in the last 24 hours show the thin line between profits and losses.\n$805 million Liquidated\nBitcoin made quick gains in the early hours of the day, surging past the $18,000 barrier to set a new yearly high of $18,472. Soon after achieving this milestone, Bitcoin suffered a flash crash within minutes, dropping to $17,200.\nThis culminated in a pump of 11%, followed by a dump of 7%. The sudden rise and drop affected traders on top crypto platforms, with about $805 million liquidated during this period. This data was represented by ByBt.com, which posted a liquidation chart of some of the top crypto platforms.\nBitcoin dominated the list, with traders losing $617 million, representing 76% of the total losses. Ethereum traders suffered the second-most losses with $88.3 million liquidated during this period. On close observation of the chart, the major losers on most of the exchanges were traders that shorted. Binance was the only exception, with 51.6% of losses falling to traders that longed their crypto assets.\nThis development shows how volatile the crypto market can be as Whales are capable of manipulating the market. The recent bullish run has surprised many as Bitcoin has continued to surge despite anticipation of an extended bearish period. Bitcoin has corrected in the past few hours and is currently valued at $17,825.\nVeteran Crypto Trader Warns Traders to Use StopLoss\nOne of the reasons why traders typically lose money during volatile swings from Bitcoin is a lack of protective measures. Veteran trader Peter Brandt today warned crypto traders to utilize stop losses during trades. Brandt suggested that the major reason traders lose is the lack of stop losses in a tweet to their followers.\nHe further added that the advice also applied to leading cryptocurrency Bitcoin. With the latest developments regarding traders liquidating on trades, Brandt’s advice is particularly useful.", "pred_label": "__label__POS", "pred_score_pos": 0.8336926698684692}
{"content": "Scientists are shedding new light on the importance of light-sensing cells in the retina that process visual information. The researchers isolated the functions of melanopsin cells and demonstrated their crucial role in the perception of visual environment. This ushers in a new understanding of the biology of the eye and how visual information is processed.", "pred_label": "__label__POS", "pred_score_pos": 0.8908224701881409}
{"content": "Kirsty Williams, Minister for Education\nIn September, I advised Members of a revised timetable for laying the Additional Learning Needs (ALN) code and operational regulations, which remain a key priority for this Government. These will be laid before the Senedd in February 2021 to support the commencement and phased roll out of the ALNET Act from September 2021. I also confirmed that the statutory roles in the ALNET Act will commence as planned, in January 2021 and that to accompany this I intended to lay regulations on the ALN Co-ordinator (ALNCo) role this year; and to publish guidance to support these statutory roles before their commencement.\nThis statement is to inform Members that on 29 October, I made an Order to commence various powers in the Act, including the power to make the ALNCo regulations, from 2 November. The Order also commences the requirements for schools and further education institutions; health boards; and local authorities to designate, respectively, an ALNCo; Designated Education Clinical Lead Officer (DECLO) and the Early Years Additional Learning Needs Lead Officer (EYALNLO) on 4 January 2021. In addition I have today laid before the Senedd the ‘Draft: Additional Learning Needs Co-ordinator (Wales) Regulations 2020’ (“the ALNCo regulations”). These regulations prescribe the qualifications and functions of the ALNCo role.\nThis role is a fundamental part of the ALN system designed to ensure a greater consistency in the designation of ALNCos and the co-ordination of additional learning provision. To support the development of this role we have allocated funding to develop an ALN National Professional Learning Programme. This is a targeted programme of training and development where tailored and timely training, relevant to the individual will be available, to help build on their existing knowledge and skills. It is intended to enable the ALNCo to fulfil their responsibilities effectively.\nThe commencement of the requirements to designate each of the statutory roles and the laying of the ALNCo regulations marks a significant milestone in the progress of these crucial ALN reforms, for the benefit of all children and young people in Wales.\nThe Order also commences provision for establishing a list of Independent Special Post-16 Institutions (ISPIs) as outlined in the ALNET Act, and I intend to lay regulations relating to this in due course.", "pred_label": "__label__POS", "pred_score_pos": 0.9972384572029114}
{"content": "It is critical to pause, reflect, and recognize that cities who are not equitable will always be in recovery mode. Inequity is a noted stress in the language of resilience shocks and stresses. It increases the probability and severity of shocks – like social uprisings and the civil unrest we have seen unfold. This holds true for a vast range of other natural and man-made shocks.", "pred_label": "__label__POS", "pred_score_pos": 0.9999592304229736}
{"content": "PRM Engineering Services was engaged by a Roads and Infrastructure client to explore options for using vision technology to prevent incorrect discharge of hot asphalt during loading activities at facilities in Victoria.\nThere had previously been incidents where hot asphalt was accidentally discharged over the cabin of trucks due to the truck tray not being located correctly under the discharge chute. With temperatures of over 150°C, the risk of serious injury and damage to vehicles in such an event was significant and needed to be prevented.\nPRM Engineering Services presented a range of possible solutions for accurately identifying the cab and trailer position within the discharge area. Using the information from the vision sensors, the system indicates to the plant operator whether or not the truck is located correctly under the discharge chute.\nThe system successfully deals with all truck and tray sizes, from small tippers to large articulated vehicles, while operating reliably in an industrial environment with steam, dust and fumes.\nNext steps may include integrating the system truck location information into the control logic of the plant, so that confirmation of a correctly positioned truck tray forms part of the automated plant control processes, further removing the risk of human error.", "pred_label": "__label__POS", "pred_score_pos": 0.9850248694419861}
{"content": "© The Author(s) 2013. Long-fiber thermoplastic (LFT) composite materials are rapidly expanding in automotive, transportation, and recreational industry. Most of these materials are natural or black in color with a need for secondary painting of the manufactured products. Standard organic pigments and dyes are not stable above 250°C and degrade during processing. Alternatively, inorganic pigments are thermally stable to at least 800°C. High-performance inorganic pigments offer resistance to outdoor weathering, chemicals, and acids. However, in fiber-reinforced composites, the pigment causes fiber attrition and thereby shows reduction in strength. This work explores colored inorganic-pigmented LFT composites. The ability to integrate the color in the manufacturing steps eliminates the need for secondary painting. Pigment variables such as particle size, distribution, chemistry, and coatings have been investigated. The article presents the processing and performance envelopes of colored inorganic-pigmented LFTs in comparison with unpigmented standard LFTs.", "pred_label": "__label__POS", "pred_score_pos": 0.8005954623222351}
{"content": "The naturally derived vegetable acid proposed to reduce sebum production, reduces P. acnes bacteria, and prevents discoloration caused by inflammation or UV exposure.\nA lipo-hydroxy acid, LHA exfoliates the skin, decongests clogged pores, refines the skin’s surface, and has anti-inflammatory effects.\nThis beta-hydroxy acid refines the pores and helps reduce acne.", "pred_label": "__label__POS", "pred_score_pos": 0.9987284541130066}
{"content": "By Kosol Suriyaporn, Director JTJB International Lawyers Co., Ltd Overview Information\nEffective from 29th December 2018 onward, International Business Center (so-called “IBC”) tax incentives under the Royal Decree No 674 was enacted to replace all previous tax-incentivized of the Regional Operating Headquarters and International Headquarters (so-called “ROH” and “IHQ” respectively).\nThe existing ROH and IHQ companies are still eligible for the previous tax benefits under the existing conditions until expiration of their approval. However, those tax benefits granted to the ROH companies under the Royal Decree 405 approval – which does not have a time limit – shall enjoy the tax incentives merely until the end of the fiscal year 2020. In addition, under the Royal Decree No. 674, the existing ROH companies (under the Royal Decree No. 405) and IHQ companies can terminate their ROH and IHQ registrations and apply for the IBC without penalizations resulting from such terminations. Conditions & Requirements\nOnly a company incorporated under the laws of Thailand and engaging in the following business activities with/to it affiliates in Thailand as approved by the Revenue Department (“RD”) can apply for IBC:\n1. Providing administrative and technical support services; 2. Providing money management services; and/or 3. Providing international trading services.\nOther essential legal requirements for applying the IBC companies are as follows:\n1. The company (applicant) must file an application and obtain an approval from the RD;\n2. The company must have its paid-up capital at least 10 million Baht on the last day of each financial year; 3. The company must provide qualifying support services or treasury services to its affiliated/associated companies; 4. The company must have at least 10 skilled full-time employees or at least 5 employees in case of IBC providing money management services; and 5. The company must have the local spending at least THB 60 million per fiscal period unless converted from ROH or IHQ. Tax Incentives\nUnder the Royal Decree No 674, a granted IBC company shall enjoy 15 financial years (of the company) the following tax incentives from the date of approval by the Revenue Department:\n1. Entitled to reduce its corporate income tax rates on the net profits from qualifying service fees and royalty incomes earned from its Thai and overseas affiliated/associated enterprises:\na. 8% when its annual operating expenditure of not less than 60 million Baht;\nb. 5% when its annual operating expenditure of not less than 300 million Baht; and c. 3% when its annual operating expenditure of not less than 600 million Baht.\n2. Exempt from corporate income tax on dividends received from its associated companies;\n3. Exempt from specific business tax on incomes from treasury services; 4. Exempt from withholding tax on dividends distributed by the IBC to its overseas shareholders that are paid out of the reduced-corporate income tax profits of the IBC’s operations; and out of defined qualifying profits from the ROH’s/IHQ’s operations within one year after the conversion to an IBC is approved; and 5. Exempt from withholding tax on interest paid by the IBC to an overseas loan provider in connection with a loan obtained for re-lending due to its treasury activities.\nLastly, the IBC company’s expatriated employees also can enjoy to a flat personal income tax rate of 15% for employment remuneration derived from working full time.", "pred_label": "__label__POS", "pred_score_pos": 0.5414453744888306}
{"content": "We introduce a new task, Video-and-Language Inference, for joint multimodal understanding of video and text. Given a video clip with aligned subtitles as premise, paired with a natural language hypothesis based on the video content, a model needs to infer whether the hypothesis is entailed or contradicted by the given video clip. A new large-scale dataset, named Violin (VIdeO-and-Language INference), is introduced for this task, which consists of 95,322 video-hypothesis pairs from 15,887 video clips, spanning over 582 hours of video. These video clips contain rich content with diverse temporal dynamics, event shifts, and people interactions, collected from two sources: (i) popular TV shows, and (ii) movie clips from YouTube channels. In order to address our new multimodal inference task, a model is required to possess sophisticated reasoning skills, from surface-level grounding (e.g., identifying objects and characters in the video) to in-depth commonsense reasoning (e.g., inferring causal relations of events in the video). We present a detailed analysis of the dataset and an extensive evaluation over many strong baselines, providing valuable insights on the challenges of this new task.", "pred_label": "__label__POS", "pred_score_pos": 0.988613486289978}
{"content": "You likely hoped that you and your spouse would begin your divorce on a level financial playing field. Yet, they may have had other intentions, which you discovered once you found your joint bank and savings accounts drained. Scrambling for funds will add extra challenges to your divorce. Yet, your main concern might be whether your spouse will be held accountable for their actions. Though they may, their consequences could depend on when they withdrew the funds from your accounts.\nBefore filing for divorce\nDuring your marriage, you and your spouse could access and withdraw the funds in your joint accounts at any time. Yet, while emptying them is technically legal, it is inadvisable. Before filing for divorce, the general guideline is to withdraw no more than 50% of the funds in your joint accounts. If your spouse drained them, it is unlikely that Michigan courts will condone their behavior. Any penalties your spouse faces will reflect the severity of their actions. They may have to restore your share of funds or give you property of equal value in exchange for them.\nAfter filing for divorce\nAfter you or your spouse filed for divorce, you may have requested and received an ex parte order to uphold the status quo of your joint accounts. This order exists to prevent you and your spouse from withdrawing funds from them, aside from those needed for living expenses. Keep in mind, though, that state courts will not inform the financial institutions holding your accounts of this order. Yet, if your spouse drained them after the order was issued, they could face contempt of court charges. Besides restoring the missing funds, they may also have to pay your attorney’s fees, as well as a fine.\nIf you find your spouse has emptied your joint accounts, you must act swiftly. An attorney with family law experience can help you consider your options for restoring your financial status quo.", "pred_label": "__label__POS", "pred_score_pos": 0.9959467649459839}
{"content": "Every rider understands the importance of motorcycle safety, but the helmet debate remains a controversial subject for motorcyclists across the country. Some believe it’s a simple matter of protection, while others believe that federal law should stay out of their business. So, should helmets be mandatory?\nIn Support\nThe primary argument for mandatory helmet laws is that they save lives. A motorcycle accident lawyer in California points out that fatal accidents decreased by 37% after the state passed its helmet law. This was due to an 49% increase in helmet use, covering roughly 99% of riders.\nThe National Highway Traffic Safety Administrations found a similar trend with helmets reducing fatal accidents across the country by 37%. This decrease comes from neck and head protection, significantly limiting the injuries those parts of the body receive in an auto accident.\nAside from the safety aspect, proponents also point to theft. Motorcycle thieves rarely bring a helmet with them, allowing a mandatory law to make these culprits easier to identify. Texas witnessed a 44% decrease in motorcycle theft after passing their law.\nOthers argue that most countries already have mandatory helmet laws in place, but the final main point to remember is insurance related. With the high cost of medical bills after an accident, insurers often require that riders wear a helmet to receive coverage. This leaves the public to pay for their medical costs, which also includes the uninsured.\nIn Opposition\nThe main argument against a mandatory law is that it would allow the federal government to supersede states’ rights, effectively infringing on America’s very design. Organizations and individuals alike argue that educating riders is far more effective than any law in ensuring their safety.\nSome agree that minors should wear helmets, but believe that adults have the right to make that decision for themselves. Others believe that every rider should wear a helmet, but no law should force them to do so.\nMost individuals against helmet laws also agree that they do not ensure the safety of the rider in the event of an accident. Instead, riders should follow safe practices to avoid dangerous situations altogether. They believe that these laws do not prevent accidents, therefore they are useless.\nFinally, some point to a few studies that show medical costs are on par with other types of drivers and that the public does not pay more than they would in any other scenario. Furthermore, most accidents involving a motorcycle tend to be the other party’s fault. Relying on personal injury attorneys, riders can have their medical costs covered.\nThe Final Verdict\nWhether or not helmet laws for motorcyclists should be mandatory is a highly controversial issue. Unfortunately, the debate remains at a standstill and up to individual states to determine. Congress is still unsure of their role in a mandatory law and if one would be constitutional.\nHowever, both sides agree that helmets add a level of safety when riding in the event of an accident. While the jury is out on legality, choosing to wear a helmet can save your life.", "pred_label": "__label__POS", "pred_score_pos": 0.6999419927597046}
{"content": "Published February 6, 2020\nHow to Cite\nGucsi, L. (2020). Methods of Identification for Ceramics with Traces of Secondary Burning and their Occurrences in Mortuary and Ritual-related Assemblages.\nDissertationes Archaeologicae, 4, 215-240. https://doi.org/10.17204/dissarch.suppl3\nAbstract Among archaeological assemblages recovered both from settlement sites and burial grounds, the presence of ceramics with traces of secondary burning is a relatively common phenomenon. The identification of such traces can nuance the interpretation of the archaeological contexts within which these ceramics occur. In case of cremation burials, it can highlight the details of the cremation process. However, most publications seem to mention secondarily burnt ceramics either when the pieces are clearly severely burnt, deformed or blistered, despite these cases being only partial representations of the whole phenomenon. Based on previous experience, three levels of secondary burning can be distinguished on archaeological ceramics: slight, moderate and severe secondary burning. This more detailed classification could aid the reconstruction of funerary rituals. The recognition and the correct identification of such ceramic pieces can provide details on whether a certain vessel (or vessel types) was/were placed on the funeral pyre or was only tangentially involved in the cremation process.", "pred_label": "__label__POS", "pred_score_pos": 0.6953490972518921}
{"content": "The North Connemara Locally Led Agri-Environmental Scheme is a local agricultural scheme to incentivise farmers to incorporate agricultural animals in improving the ecology of their land.\nProjects & Practice\nAn award-winning organic farm in Finland set up a food production network with neighbouring farms aiming to achieve energy and nutrient self-sufficiency.\nUsing RDP support to turn a farm into a nature reserve; contributing to tackling biodiversity loss.\nMaintaining natural and semi-natural meadows and wetlands to ensure suitable nesting conditions for an endangered bird species: the Aquatic Warbler.\nPunkalaidun municipality conducted a feasibility study for setting up a biogas plant producing energy from manure, which resulted in an investment decision.\nA regional cooperative chain for biomass was established to respond to the increasing demand for woodchip.\nAgri-environment cooperatives in the Netherlands use results-based schemes to distribute payments to farmers according to on-farm nature conservation results.", "pred_label": "__label__POS", "pred_score_pos": 0.7243168354034424}
{"content": "We have identified the tracheal and laryngeal afferent nerves regulating cough in anaesthetized guinea-pigs. Cough was evoked by electrical or mechanical stimulation of the tracheal or laryngeal mucosa, or by citric acid applied topically to the trachea or larynx. By contrast, neither capsaicin nor bradykinin challenges to the trachea or larynx evoked cough. Bradykinin and histamine administered intravenously also failed to evoke cough. Electrophysiological studies revealed that the majority of capsaicin-sensitive afferent neurones (both Adelta- and C-fibres) innervating the rostral trachea and larynx have their cell bodies in the jugular ganglia and project to the airways via the superior laryngeal nerves. Capsaicin-insensitive afferent neurones with cell bodies in the nodose ganglia projected to the rostral trachea and larynx via the recurrent laryngeal nerves. Severing the recurrent nerves abolished coughing evoked from the trachea and larynx whereas severing the superior laryngeal nerves was without effect on coughing. The data indicate that the tracheal and laryngeal afferent neurones regulating cough are polymodal Adelta-fibres that arise from the nodose ganglia. These afferent neurones are activated by punctate mechanical stimulation and acid but are unresponsive to capsaicin, bradykinin, smooth muscle contraction, longitudinal or transverse stretching of the airways, or distension. Comparing these physiological properties with those of intrapulmonary mechanoreceptors indicates that the afferent neurones mediating cough are quite distinct from the well-defined rapidly and slowly adapting stretch receptors innervating the airways and lungs. We propose that these airway afferent neurones represent a distinct subtype and that their primary function is regulation of the cough reflex.", "pred_label": "__label__POS", "pred_score_pos": 0.8723119497299194}
{"content": "This thesis constitutes a comparative study of contextualised language, concerned with the recurring rhetorical form of the pre-battle harangue in Latin historical narratives. Focusing upon battle rhetoric produced in the context of the early crusadingmovement, it utilizes comparative non-crusading material from a long twelfth century. Centrally the dissertation challenges previous scholarship which understood battle rhetoric as providing a direct insight into the psychology of medieval soldiery, that was by and large generic in nature. Instead, this thesis contends that battle rhetoric was an ideal opportunity for authors to dynamically emphasise particular themes, present didactic lessons and explore ideas of virtue, justice and faith through direct speech at climactic moments. Chapter One explores the classical and scriptural underpinnings of the teaching and use of rhetoric in medieval western Europe and contextualizes the Roman tradition of rhetoric as it came down to the twelfth century. It displays how the rhetorical tradition which influenced medieval authors presented the ‘invention’ of orations as more than ornamentation, and that the aims of rhetoric to teach, move and please involved a commitment to truth, ethics and moral worthiness. The remainder of the thesis applies this understanding of rhetoric to orations from accounts detailing crusading expeditions of the twelfth century. Chapter Two examines one of the earliest accounts of the First Crusade, the Gesta Francoum, identifying the most significant themes and tropes of its orations. These themes and motivational appeals serve to structure a wider exploration of First Crusade sources in Chapter Three. Chapter Four and Five each focus on a\nsingle text, concerned with the Second Crusade and the Third Crusade respectively. Alongside comparative material, these chapters chart the development or disappearance of particular ideas in battle rhetoric, and account for the shifting priorities and aims of oration authors into the early thirteenth century.", "pred_label": "__label__POS", "pred_score_pos": 0.6161448359489441}
{"content": "Abstract\nVarious forms of cobalt catalysts have been studied extensively for selective aerobic oxidation of hydrocarbons. However, it remains unclear whether cobalt can directly activate molecular oxygen under mild reaction conditions. Here we investigated the catalytic roles of cobalt in ethylbenzene oxidation with and without a hydroperoxide initiator. The contribution of different cobalt species was studied by varying the metal loading on Co-impregnated ZSM-5 samples. Quantitative EPR was used to determine the impact of cobalt catalysts on the free radical concentrations. This work provided strong evidence that cobalt, in several different forms, catalyzes hydrocarbon oxidation by facilitating peroxy bond cleavage, instead of direct oxygen activation.\nKeywords Cobalt Ethylbenzene Hydroperoxide Oxidation ZSM-5 ASJC Scopus subject areas Catalysis Chemistry(all)", "pred_label": "__label__POS", "pred_score_pos": 0.8121562600135803}
{"content": "The historical development of Hòa Hảo Buddhism is the nexus around which this study is built. The history of Hòa Hảo Buddhism includes two distinct but closely interrelated stages, namely the age of Bửu Sơn Kỳ Hương and the era of Hòa Hảo Buddhism.\nThe\nBửu Sơn Kỳ Hương\nmovement emerged in mid-19\nth century, just before the French colonial\nconquest of the South. Therefore this movement might be viewed as a product of\nthe antecedent historical phenomena, notably the Southward Movement, or Nam Tiến. It should be pointed out that\nthe rise of Bửu Sơn Kỳ Hương coincided with a process of subsequent\ncolonization of the South by Vietnamese settlers.\nIn the wake of military conquest and colonization by Vietnamese settlers, the social institutions of the south soon began functioning in a way similar to other parts of Vietnam. It happened despite the continued presence of a considerable Khmer population with their distinct traditional way of life, religious and social customs and practices. However, in the course of its adaptation, the traditional Vietnamese culture was enriched by new characteristics of the Mekong Delta, eventually described as the local characteristics of southern Vietnam.\nIt might be argued that due to the differences mentioned above, popular and revolutionary organizations in the south typically emerged as religious movements and not in the guise of political parties, as it was the case in north and central Vietnam. Two reformist religions, Hòa Hảo Buddhism and Caodaism, later gained mass followers and were often cited.\nHòa\nHảo Buddhism emerged in the mid-20\nth century as a direct continuation\nof the Bửu Sơn Kỳ Hương\ntradition. However, the rise of Hòa Hảo Buddhism took place within the\nbackground of French colonial domination.\nThe Bửu Sơn Kỳ Hương movement was initiated in 1849 by Đoàn Minh Huyên. Subsequently, he was venerated as Phật Thầy Tây An, or Buddha Preceptor of the Western Peace. From a socio-cultural point of view, the emergence of this religious movement might be viewed as the Vietnamese settlers’ cultural reaction to the new conditions of life. Pioneers, who were colonizing new areas, arguably needed a sort of ideological footing. This is why the founder of the Bửu Sơn Kỳ Hương movement opted to rely on two main principles, Faith and Patriotism. Therefore, the people who lived under unstable social circumstances were given positive social and religious ideas. Correspondingly, their way of life, which had previously lacked any concrete direction, could have been driven towards religious and national values. The emergence of Bửu Sơn Kỳ Hương movement arguably indicated that the considerable potential of Vietnamese culture, though weakened by frontier conditions in the South, was nonetheless sustained and developed within the framework of the new faith.\nIn doctrinal terms, the Bửu Sơn Kỳ Hương was not a new religious teaching, as it was a largely a Buddhist movement. Moreover, since Phật Thầy Tây An relied upon the principles of Faith and Patriotism, the Bửu Sơn Kỳ Hương emerged as a Buddhist movement with strong patriotic overtones.", "pred_label": "__label__POS", "pred_score_pos": 0.8058579564094543}
{"content": "Systematic Trend Following Every truth passes through three stages before it is recognized. In the first it is ridiculed, in the second it is opposed, in the third it is regarded as self-evident.\n—Arthur Schopenhauer\nTactical trend trading can be done on either a discretionary or a systematic basis, and the trader can apply these methods to stocks, bonds, commodities, and other traded liquid markets. As the title of this chapter makes clear, however, my focus is on systematic trend following, which entails gathering the best practices and rules of successful traders, incorporating them into a computer-coded trading system, and then following ...", "pred_label": "__label__POS", "pred_score_pos": 0.5320581197738647}
{"content": "Background: The most part of Iran become malaria - free region and fall in prevention of re-introduction stage. These regions however are struggling with imported of malaria cases where malaria vectors exist. Therefore, understanding the situation of mosquito vectors is crucial. This study was carried out to find out the present situation of malaria vectors and malaria transmission potential in a malaria-free area.\nMethods: The study was conducted in a malaria free area, Izeh County, Khuzestan Province during 12 months in 2011–2012. Five villages, including 2 in highlands and 3 in plain area, were selected randomly. The mosquito sampling methods were conducted using spray sheet and hand catch collection methods from indoor/outdoors, window trap and larvae collections. Results: In total, 3352 female Anopheles were captured, 1826 mosquito from highland and 1526 from plain areas. Five species, An. stephensi, An. fluviatilis s.l., An. dthali, An. superpictus and An. pulcherrimus were identified. The seasonal activities were started from April to March. The abdominal conditions of collected mosquitoes from indoor/ outdoor places pointed to exophilic propensity of An. fluviatilis.l. s.l. and endophilic behaviour for rest of the vectors. The results of window trap also confirmed these behaviors. The larval habitats of four species were widely dispersed and included spring, margin of rivers, irrigation channels, stagnant water and rice filed. Conclusion: Understanding the present situation of malaria vectors in free-malaria area is crucial particularly where is struggling with imported cases. The results of present study can be expanded to other area of northern Khuzestan for malaria vector control planning in reintroduction prevention stage.", "pred_label": "__label__POS", "pred_score_pos": 0.6117783784866333}
{"content": "Public and commercial buses provide the residents of Kenneth City with a convenient, affordable mode of transportation. Whether it is to get to work or attend an appointment, these buses are generally reliable and inexpensive to use. However, when buses are involved in a collision with other motorists or pedestrians, the potential for injury is high. This includes not only the other motorists but the bus passengers as well.\nIf you sustained injuries a bus crash, you may need help from an aggressive personal injury attorney. If a negligent bus driver is responsible for your injuries, you could have a potential claim for monetary compensation. A Kenneth City bus accident lawyer could help you fight for damages against the responsible parties.\nFactors in a Bus Crash\nCareless and reckless actions by a bus driver are a common cause in these types of collisions. The circumstances that led an operator to cause a bus crash can vary. Examples include:\nIntoxicated driving Following traffic too closely Running a red light Fatigue Aggressive driving Failure to yield\nAny of these factors commonly cause bus operators to strike a nearby vehicle or even a pedestrian, but there are other potential causes of a bus collision outside of driver error. Bus accidents may also occur due to mechanical defects or poor road maintenance or if the vehicle was not maintained properly.\nOther motorists are not the only ones that could potentially suffer injuries in a bus accident claim. The passengers on a bus are also at risk for injury. Most busses lack seatbelts which could result in a crash throwing passengers around the cabin or out of the vehicle. These passengers also risk injury from luggage or other items falling in a bus crash.\nAny of these factors could result in a viable claim for monetary compensation. A Kenneth City attorney could advise a bus accident victim on how to best recover the money they need to cover their damages.\nIdentifying Defendants in a Bus Accident Lawsuit\nBus accidents are often chaotic. Given their size, it is not unusual for busses to collide with multiple vehicles at the time of a crash. A bus accident attorney in Kenneth City could carefully investigate a crash scene to identify all of the responsible parties. In many cases, a variety of factors will cause an accident by occurring at the same time. Often, one of these factors alone might not be enough to cause the crash. When the two come together, they could result in a large claim for compensation.\nWho the potential defendants are in a bus crash lawsuit depends entirely on the facts surrounding the specific accident. While the driver of the bus is a common defendant, there are other people or entities that could also face responsibility for the accident. Some examples include:\nBus companies State or local government Bus manufacturers Maintenance companies Work with a Kenneth City Bus Accident Attorney\nIdentifying the cause of an accident or the potential defendants is only the first step in a bus accident claim. Your attorney must review the evidence and build a strong claim before you have the opportunity to recover compensation.\nThe earlier you select your Kenneth City bus accident lawyer, the sooner compensation could become a reality in your case. Reach out to set up a consultation and get started on your claim immediately.", "pred_label": "__label__POS", "pred_score_pos": 0.8288617134094238}
{"content": "Will Ammonia Kill Mold on Wood Furniture?\nMold and mildew are types of fungi that accumulate on damp surfaces, including wood furniture. Both of these unwanted fungi can be treated and removed with ammonia, which is typically combined with water and other household substances that aid in killing the spores.\nWash, Scrub and Rinse\nMold and mildew most often accumulate on outdoor furniture that is exposed to moisture in the air. However, indoor furniture is also susceptible due to spores that enter through windows, open doors and ventilation systems. Mildew, a specific type of mold, is typically the culprit on hard surfaces, so ammonia is a good choice for removing it. Unfinished, painted and glazed wood furniture can all be treated with a mixture of 1-cup ammonia, 1/2-cup vinegar, 1/4-cup baking soda and 1 gallon of water. Wash the entire piece of furniture with the solution, scrubbing as necessary in sections with visible accumulation of mildew. Rinse thoroughly and allow the piece to dry in fresh air, preferably outdoors.\nTake Care\nAmmonia should never be mixed with bleach; the combination produces dangerous toxic fumes. Always use ammonia, or any other cleaning solutions, in well-ventilated areas. Protect your skin with rubber gloves, and use protective eyewear if you anticipate long exposure to fumes from ammonia solutions.\nReferences\nResources\nWriter Bio\nWendy K. Leigh is a travel writer and photojournalist from Seattle. She is the Editor of Islands America, a travel website for visiting islands within the United States. She also writes about home design, food and historical architecture. Leigh holds a Bachelor of Arts in English from the University of Washington.", "pred_label": "__label__POS", "pred_score_pos": 0.786536693572998}
{"content": "Abstract\nCopolyamides, based on 1,12-dodecanedicarboxylic acid and different ratios of 1,2-ethylenediamine and piperazine, i.e., PA2,14-co-pip,14 as well as the homopolymers PA2,14 and PApip,14 are studied. Incorporation of the piperazine component in the homopolymer PA2,14 reduces the number of hydrogen bonds. This provides a unique opportunity to investigate the influence of hydrogen bonding on the origin of the Brill transition and chain mobility within polymer crystals. Time-resolved conformational, structural, and morphological changes during heating are followed by FTIR spectroscopy, WAXD, and SAXS. The findings are that from 0 to 62 mol % of piperazine the Brill transition occurs in the same temperature region. The transformation is triggered by the conformational changes in the methylene sequences of the main chain, followed by twisting in the methylene sequences next to the amide group. This results in enhanced chain mobility along the c-axis, causing lamellar thickening. For 80 mol % of piperazine and higher, no Brill transition is observed. However, conformational changes in the methylene sequences of the main chain occurs, triggering lamellar thickening.", "pred_label": "__label__POS", "pred_score_pos": 0.865605354309082}
{"content": "The ACT government's rent reduction scheme will be extended until the end of the year.\nIt will mean landlords who reduce tenants' rent by at least 25 per cent can continue to receive rebates on land tax of up to $100 a week.\nOnly tenants who have been impacted by the coronavirus pandemic are eligible for the reduction.\nThe scheme was implemented in April as part of the government's coronavirus economic response. It was intended to go for six months.\nAs of August 13, 759 landlords had applied for the rebate. They will have to apply again to extend the rebate.\nACT Attorney-General Gordon Ramsay said he was pleased at the number of landlords who had applied for the scheme.\n\"We understand this is a difficult time for many Canberrans, particularly those who have suffered a significant reduction in their income,\" he said.\n\"However, I want to remind people that this isn't a license for tenants to completely forgo their rental obligations. If you are not impacted by COVID-19 and can pay your rent then you are required to do so.\"", "pred_label": "__label__POS", "pred_score_pos": 0.9961728453636169}
{"content": "Heroes of the pandemic: School teacher SOME people are still required to go to work during this national shutdown. We're speaking with essential workers to hear how their jobs have changed and how they're keeping things turning in the Central Highlands. We'll bring you their stories.\nDAVID Carter always wanted to be a teacher. The 32-year-old father followed his dream two years ago and has since been teaching science and modern history to high school students at Emerald Christian College.\n\"I like sparking the curiosity in their minds about the world, especially being science, understanding how things happen,\" he said.\n\"When they figure it out for themselves, that's what every teacher loves. That 'ah-ha' moment is probably the gold mine.\"\nOne of the challenges of home-based learning was that it had limited the hands-on aspects of teaching.\n\"With science you deal with things in the abstract, you talk about a force but what does that mean?\n\"When you visually show them and do experiments, that's what science is.\n\"And that's been the hardest thing, trying to embed experiments they can do at home, without the equipment.\"\nUnlike many other essential workers, Mr Carter has also faced the challenge of having a young daughter with a weak immune system, putting her in the high-risk category during the pandemic.\nAlthough he and his wife weren't too worried initially, it \"started to hit home\" when the first coronavirus case was reported at the Brisbane hospital where his daughter was born.\n\"You start hearing rumours there's a case around Blackwater, Moranbah, Gracemere, and we have family there so you're more concerned for them,\" Mr Carter said.\nHe was told to stay home during the first week of Term 2 for his family's safety, but he jumped at the chance to head back to the classroom when the time came.\n\"I was climbing the walls at home, so I think my wife fully supported the decision,\" Mr Carter said with a laugh.\n\"Don't get sick, that's the only thing she said to me.\"\nWhile some students have thrived in the home environment, others haven't done so well, and Mr Carter expects it to be a difficult transition back to the norm.\n\"We are continually assessing the students so we have an idea of where they're at but we have to take into consideration everything that's happened,\" he said.\n\"Some students have got all the resources and can engage properly and others not so much, so it's an unfair advantage.\n\"It will be more of a day by day basis.\"", "pred_label": "__label__POS", "pred_score_pos": 0.6174259781837463}
{"content": "Jost Wübbeke\nEnergy Security Discourses and Strategies in China and the EU – A Comparison\nBetreuer / supervisor:\nProf. Dr. Miranda Schreurs\nDescription:\nChina’s rare earth industry is currently undergoing a profound transformation. The central government is pushing forward the reorganization of the industry, tightening standards for environmental protection and resource conservation, and controlling exports. The current debate revolves very much around the Chinese export controls while underemphasizing the dimension of the domestic policies. The leading research question of this dissertation is: why, how and how should the Chinese central government carry out a profound transformation of the rare earth industry? The research focus of this dissertation is threefold: first, I seek to examine the motives of the central government in pushing forward this transformation. In a second step, I analyze the concrete measures and their efficacy. Thirdly, I assess to what degree the government efforts can be associated with the concept of post-extractivism. The analysis relies on actor-network theory as a conceptual framework.\nGrants:\nPhD Scholarship by Heinrich-Böll Foundation\nPublications:", "pred_label": "__label__POS", "pred_score_pos": 0.6050360798835754}
{"content": "The Perfect BAC is a project aimed at reducing the share of students that drink too much alcohol. The goal is to contribute to a safe and inclusive environment for all students.\nTo achieve this goal, we assist student associations that want to work on their alcohol policy. We contribute with information and competence, so that they can implement measures suitable for their organization. These measures can be better guidelines for alcohol consumption, enforcement of rules, and alcohol free events.\nWe offer «The Perfect BAC» material for your organization Workshop in alcohol policy Help and guidance if you are concerned about your or others alcohol/drug use How to reach the Perfect BAC\nTo reach the Perfect BAC, women can drink 2 alcohol units, while men can drink 3–4. Then, drink 1 unit per hour, and alternate with water to keep hydrated. That way you reduce the chance of a hangover.\nYou can test your alcohol habits anonymously.\nIf you have any questions, please do not hesitate to contact our project leader, Maren Kronlund: maren.kronlund@sit.no", "pred_label": "__label__POS", "pred_score_pos": 0.9331960678100586}
{"content": "Execute Savings Initiatives That Have the Highest Likelihood of Success Inability to Prioritize Initiatives\nAs healthcare organizations continue to brace for the shift toward value-based care, the focus on achieving real cost reduction is growing. Organizations typically have hundreds of opportunities to reduce cost, increase efficiency, and improve. It is overwhelming to determine exactly where to start. Healthcare providers need a way to identify which initiatives should be prioritized and resourced.", "pred_label": "__label__POS", "pred_score_pos": 0.9987799525260925}
{"content": "May 2018 Workplace Mental Health\nEmployee mental health is one of the most significant challenges faced by employers today. The immense costs of mental health are due to the high prevalence of mental health conditions as well as insufficient or ineffective treatment. This issue of\n@Work magazine features a variety of program models and approaches to address mental health conditions in the workplace.", "pred_label": "__label__POS", "pred_score_pos": 0.9264436960220337}
{"content": "Netaly Ophir-Flint Netaly Ophir Flint is a Partner at KONU - an international consultancy for leadership development and change management that specializes in the art of Adaptive Leadership. At KONU, she works with mission-driven individuals, executives, and organizations to help them adapt and thrive as they tackle complex challenges in a rapidly changing world. Until recently, Netaly served as the CEO of the Reut Institute Group - a 21st Century think tank and leadership group designed to address the most pressing issues facing Israel and the Jewish people. In the past, Netaly led Reut’s groundbreaking work on the changing relations between Israel and world Jewry, specifically focusing on the Israeli Diaspora as a catalyst for Jewish Peoplehood. Netaly holds a Master’s Degree in Public Administration from the Harvard Kennedy School of Government as a Wexner Israel Fellow and a dual MA in International Relations and Conflict Management and Resolution from the Hebrew University in Jerusalem. She is also a certified mediator and facilitator.\nSunday 22nd Nov\nLeadership for Turbulent Times We are currently living In a volatile, uncertain, complex, and adaptive world. The need for progress and change on difficult systemic issues is all around us: digitalization, political uncertainty, race and inclusion, financial upheaval, and the list goes on. In this context, people are increasingly called on to lead their teams and communities through significant operational and cultural reforms. However, the attributes that served our management well in the past - technical expertise, respect for functional and industry boundaries, and deference to hierarchy - are no longer sufficient. To survive and thrive in this environment, more adaptive approaches are needed. In this session, we will draw on the Adaptive Leadership Framework – developed at Harvard’s Kennedy School – to gain insights into how to navigate these turbulent times. Join us to deepen your leadership practice for this crucial moment in history.", "pred_label": "__label__POS", "pred_score_pos": 0.7861404418945312}
{"content": "Occupational Adaptation Model (OAM) is proposed as a frame of reference that aims to integrate the two main domains (occupation and adaptation) for occupational therapy. It defines occupation as self-perceived meaningful activities that require active participation and lead to a product. Adaptation is one’s adaptive response to meet an occupational challenge, when ordinary response is insufficient to master the activity, and is evaluated in relation to the concept “relative mastery” (i.e., evaluating occupational performance from the client’s viewpoint). The increase and maintenance of competence in activities are described as an interaction between a person and his/her environment. Occupational adaptation process begins with the environmental demands for mastery in activities. This OAM assumes that individuals have the desire to master activity and gain the environmental control. It emphasizes on the person’s interaction with the natural setting for occupational performance. With this frame of reference, the patient should actively participate and engage in goal setting, treatment planning, and evaluation. In the assessment, questions based on the OAM are asked to identify the person’s occupation environments, roles, and meaningful activities. During treatment planning, the client chooses meaningful activities that he/she would like to master. Treatment focuses on the self-chosen activities and the client’s environment and roles. The evaluation will be based on the concept of relative mastery.\nSummarized by\nMacey Cho\nType\nFrame of reference\nPopulation\nChild\nAdolescent\nAdult\nElderly\nDisability\nAll\nDomain of occupation\nUnspecified\nApplication Note\nClient’s active participation is required during the entire intervention process.\nKey Reference\nSchkade, J. K., & Schultz, S. (1992). Occupational adaptation: Toward a holistic approach for contemporary practice: I. American Journal of Occupational Therapy,46(9), 829-837.\nThe occupational adaptation frame of reference (FOR) focuses on the adaptation process when a person encounters occupational challenges. Three basic elements of this FOR are the person (including sensorimotor, cognitive, psychosocial system), the occupational environment (including work, play and leisure, and self-maintenance) and the interaction between these two elements. Each of the elements is consistently influenced by a constant, respectively.\nOccupational adaptation theory describes a process of internal adaptation. It aims to guide occupational therapy practitioners to facilitate clients’ ability to make adaptations to engage in meaningful activities. This theory emphasizes the interaction between the person and the environment. It states that the person consists of three systems (sensorimotor, cognitive, and psychosocial) that interact with occupational environment (physical, social, and cultural).\nThe Canadian Model of Occupational Performance and Engagement (CMOP-E) is an occupational performance model, which is evolved from the Canadian Model of Occupational Performance (CMOP). The CMOP-E includes three main components: person, environment, and occupation. In this model, the inner part represents “Person”, and its center is the spirituality of a person. The other components surrounding a person’s spirituality are affective, physical, and cognitive abilities.\nThe Model of Playfulness suggests that playfulness can be determined within any transaction of the evaluation of three elements, each of which can be represented as a continuum. The three elements are (1) source of motivation (from intrinsic to extrinsic), (2) perception of control (from internal to external), and (3) the suspension of reality (from free to not free). Intrinsic motivation, such as mastery or pure sensation of movement, is the aspect(s) of activity itself that provides motivation for the individual to involve in an activity.\nThis model is based on the concepts of metacognition and awareness to view the relationship between the metacognition and awareness as a dynamic process. This model differentiates between one’s self knowledge and awareness that are pre-existing or stored within long-term memory (or called metacognitive knowledge) and the knowledge and awareness that is activated during a task (or called on-line awareness).", "pred_label": "__label__POS", "pred_score_pos": 0.575544536113739}
{"content": "Each year, Radius’ team of psychologists and social workers provide help to over 430 local children and youth. The stories we hear are often heartbreaking and difficult. They are also filled with hope, resiliency and strength.\nApproximately 50% of the clients at Radius are between 12 and 18 years old. Teens like Damion receive counselling and services to help them heal from the trauma of sexual abuse.\nRadius engages non-offending parents and caregivers in our clinical assessments and counselling. This helps us better understand the needs, strengths and goals of each child, and supports parents to continue the healing journey at home.", "pred_label": "__label__POS", "pred_score_pos": 0.8784400820732117}
{"content": "Evenflo Recalls Over 56,000 Child Booster Car Seats Due to Design Defect\nEvenflo will recall approximately 56,247 Transitions 3-in-1 Combination Booster Seats due to a design defect involving the central front adjuster button. The central front adjuster (CFA) controls the seat’s internal harness to loosen the restrains on the child. It was discovered recently that the position of the CFA is in reach for the child to activate the CFA and subsequently loosen the harness that is restraining the occupant. If the internal harness is not tightened snugly around the child, this increases the risk of injury for the child in the event of a crash.\nClick here to read the full Evenflo recall: Transitions 3-in-1 Car Seat\nThe model numbers affected in this recall include 34411686, 34411695, and 34411029. These car seats were manufactured from December 18, 2014 through January 29, 2016.\nEvenflo will notify owners and provide a remedy kit that includes a replacement seat pad and CFA assembly, free of charge. This will eliminate a child’s access to activate the CFA button. The recall is expected to begin during February 2016. Owners may contact Evenflo at www.transitions.evenflo.com or 1-800-233-5921. Note: This safety issue only affects the use of the seat in the forward-facing harnessed booster (22-65 lbs. and 28-50 in.) configuration.\nRecently, Britax recalled 49,000 B-Ready strollers and replacement top seats due to an arm bar defect.\nAmericans rely on manufacturers to provide a safe well-designed product. Sadly, that is not often the case. The Auto Defect Attorneys at The Brandi Law Firm have successfully represented many people injured from defective autos such as Toyotas, Fords, Chryslers, Hondas, GM, and their component parts. Additionally, we have successfully represented people injured by defective helmets, bicycles, motorcycles, fuel pumps, brakes, car seats, seat belts, air bags, table saws, pumps, industrial machinery used in the workplace, barbeques, heating systems, and numerous other household and industrial products.\nOften times, people involved in accidents do not examine the issues of defective product design, the risks inherent in the design, feasible alternatives, and appropriate warnings. In a car accident, we examine whether the car was truly crashworthy – does it contain the appropriate crash protection. In accidents where someone strikes a guardrail, people often do not consider the guardrail may be unsafe, installed improperly, or whether there is a contributing factor in the roadway design leading to a dangerous condition. We have represented a number of people seriously injured in these types of accidents involving dangerous conditions of roads and crashworthy vehicles. If you or a loved one has been injured in an auto crash, our attorneys at The Brandi Law Firm are available to consult with you. Please contact our office at 800-481-1615 or email us.\nTrademark Notice\nEvenflo is a registered trademark of Evenflo Company, Inc. The use of this trademark is solely for product identification and informational purposes. Evenflo Company, Inc. is not affiliated with this website, and Evenflo Company, Inc. has no affiliation with The Brandi Law Firm. Nothing on this site has been authorized or approved by Evenflo Company, Inc.", "pred_label": "__label__POS", "pred_score_pos": 0.814416766166687}
{"content": "Stronger Churches is a process to strengthen the local church. These evaluative tools help assess the church's health and vitality, leading to strategic planning to enter into a preferred future. Then, the daughter church is encouraged to plant another congregation.\nStep 1: The Introduction to Stronger Churches is a one-day workshop that enables church leaders to keep a congregation focused on its task as God's agent in a particular place. It prepares leaders to guide their congregation into a self-designed path towards greater ministry effectiveness according to the ten characteristics of healthy congregational life and mission.\nStep 2: Take Your Church's Pulse is a tool that enables leaders to assess the level of health in the congregation and evaluate key areas of ministry. It serves as a tool for self-evaluation and planning for the local church, addressing both quantitative and qualitative factors. A dynamic online version of the tool is available at pulse.tycp.online.\nStep 3: The Strategic Planning Process workshop helps church leaders determine what actions the church will do, why the church will do them, and how the church will accomplish these action. With the strategic plan, leaders can be confident that biblical, sensible, and reliable details are communicated well. The result is a church with personnel focused together on accomplishing God’s Kingdom work to have a larger impact on their community.\nStep 4: We offer a Toolbox of strategies designed to help a church target the specific areas of ministry they wish to develop.\nStep 5: As a church meets its self-determined goals, it celebrates what it is becoming by God's grace and through the power of the Holy Spirit. It is then challenged to consider planting a daughter church.", "pred_label": "__label__POS", "pred_score_pos": 0.5671797394752502}
{"content": "A negative mental habit that is often a struggle for me is ruminating. My thoughts often dwell too long on what has happened. In other words, I play events over and over in my mind and relive the emotions and regret over and over again.\nBefore this became a struggle, it was something that defeated me. It continually wore me down and lived at the root of many depressive episodes and sleepless nights.\nThen God’s word got a hold of me. Specifically, two portions of scripture.\n“I am focusing all my energies on this one thing. Forgetting the past and looking forward to what lies ahead, I strain to reach the end of the race and receive the prize for which God, through Christ Jesus, is calling us up to heaven.” (Philippians 3:13-14)\n“But forget all that – it is nothing compared to what I am going to do. For I am about to do a brand new thing. See, I have already begun! Do you not see it? I will make a pathway through the wilderness for my people to come home. I will create rivers for them in the desert!” (Isaiah 43:18-19)\nAs I have revisited these verses over the years, I gradually moved from being defeated by ruminating and dwelling to struggling toward victory. These verses regularly pull me out of a downward spiral that threatens like a storm on the horizon whenever life comes at me in full force.\nTogether, these verses provide a formula of sorts for helping me to “strain to reach” and to find the “pathway through the wilderness” instead of returning to defeating and depression.\nForget: Don’t let failures and disappointments weigh you down. Don’t be held back by past success, either, by thinking the best is behind you. Look Forward: Look for what God has planned. Seek the newness he has in store. Be thankful for what he has done, then focus on what lies ahead. Receive: Keep making progress as you aim for the perfection of Heaven. Follow the way that seems impossible, but that God makes clear with every step you take toward him.\nGod ministers to me in new and increasing ways through these verses. He never fails to lead me in the path of his will through them. Now, as I enter the mid-life, empty-nest season, he once again is encouraging me through them, and I am grateful.", "pred_label": "__label__POS", "pred_score_pos": 0.7277158498764038}
{"content": "This book explores the interplay of childhood and the fairy tale as they both changed character in accordance with the historical transformations of the mid-nineteenth century. While the fairy tale was instrumental in the social construction of childhood, the latter for its part played an equally crucial role in altering the narrative structure of the fairy tale. So viewed, the story of childhood is closely intertwined with the fairy tale, and both with modernity as it changed its focus with the changing direction of the civilizing process. The liberating potential of modernity emerges when a broad spectrum of the marginalized, including children, begin to assert themselves and gain recognition as independent subjects of historical inquiry.", "pred_label": "__label__POS", "pred_score_pos": 0.9929078817367554}
{"content": "UCL School of Management’s Associate Professor Chia-Jung Tsay’s latest research examines the three fundamental responses to moral conflict; utilitarian, action and intention.\nMoral judgments are a part of daily life and decisions, especially within organisations, where differing individual’s natural instinct and moral judgments can affect the outcome of key organisational decisions.\nManagers and employees are often confronted and conflicted in the pursuit of profit or growth-oriented outcomes versus the means of achieving the outcomes, which may entail confusion and even harm to various stakeholders.\nWorking in collaboration with Harvard University, Harvard Business School and the Hebrew University of Jeresulum, Professor Tsay suggests those in managerial roles should be aware of the different individual responses to moral conflict, ensure they provide key decision makers within their organisation with all the information required and make a decision that will benefit the organisation as a whole, and consider asking the individual to set aside their inaction preference.", "pred_label": "__label__POS", "pred_score_pos": 0.8115848302841187}
{"content": "Case Scenario:\nJQ, a 58-year-old patient, has been recently diagnosed with hypertension. His resting blood pressure is 158/92. He is prescribed hydrochlorothiazide 50 mg/day and told to eat foods rich in potassium.\nAfter 1 month on hydrochlorothiazide therapy, JQ becomes weak and complains of nausea and vomiting. His muscles are “soft.” His serum potassium level is 3.3 mEq/L.\nQuestions:\nWhy is it necessary for JQ to eat foods rich in potassium when taking hydrochlorothiazide? Explain your answer. Should JQ receive a potassium supplement? Explain your answer.", "pred_label": "__label__POS", "pred_score_pos": 0.9300380945205688}
{"content": "You have a Hydra: a grand, ambitious project you’ve always wanted to tackle. It feels overwhelming, unconquerable. Chop off one of a Hydra’s heads, and two more grow in its place.\nHow will you ever defeat such a terrifying monstrosity – and live to tell the tale?\nIn this illuminating fable, productivity expert Josh Kaufman explores the uncertainty and fear inherent in facing down any ambitious challenge, from starting a new business to completing a work of art.\nThe risks involved can never be eliminated, but they can be understood, anticipated, and mitigated. Armed with an adventurer’s insights into tackling unknown and fearsome challenges, you can tame a project of epic proportions.\nHow to Fight a Hydra is an essential handbook for artists, creative professionals, and entrepreneurs tired of ignoring the call to adventure.\n.\nLink dead/Question/Request? Please touch me at ebook4expert@gmail.com\nThis free ebook is meant only for those who want to broaden their knowledge, but due to limited economic condition, cannot afford to buy on official selling channels (bookstores, Amazon, etc.). If you have money, please buy it to support the author, thank you!", "pred_label": "__label__POS", "pred_score_pos": 0.5550150871276855}
{"content": "One of the most concerning aspects of global warming is the potential for rising seas to damage infrastructure and property and displace a large proportion of our planet’s population. Since 1993, sea level has increased an average of 3.4 millimeters per year—more than twice as fast as the rate over the first 9 decades of the 20th century.\nWhen projecting future sea levels, scientists have traditionally relied upon physical models and expert assessments to project the polar ice sheets’ response to various emission scenarios. These approaches, however, haven’t taken into account some physical processes that can quickly increase ice sheet discharge, such as the collapse of terminal ice cliffs and the breakup of floating ice shelves caused by a process known as hydrofracturing.\nNow\nKopp et al. have integrated both of these processes into a probability-based modeling framework to explore how they could affect future projections of global and local sea level changes. The results indicate that these mechanisms could significantly raise sea level forecasts for high-emission scenarios, including nearly doubling the median projections of 21st century global mean sea level rise by 2100.\nMoreover, these mechanisms don’t fully kick in until the second half of the century, meaning that a global scenario leading to 50 centimeters of sea level rise over a century and one leading to 2 meters of rise won’t be distinguishable from continental-scale observations for decades to come. Reducing uncertainty will require developing a better, fine-scale understanding of ocean–ice sheet interactions. However, cutting emissions significantly affects the role these processes play: Sea level rise projections for a low-emissions scenario, consistent with the goals of the Paris Agreement, are close to unchanged by the inclusion of these mechanisms.\nBecause the researchers have not yet incorporated other important physical processes that could affect sea level into this model, such as the capacity of firn to buffer meltwater, they caution that this study does not provide unique statistical probabilities of future sea levels. Rather, it both offers a tool for exploring the sea level implications of polar ice sheets’ complex physical responses to global warming and highlights the deep uncertainty that characterizes sea level change in a high-emissions future. (\nEarth’s Future, https://doi.org/10.1002/2017EF000663, 2017)\n—Terri Cook, Freelance Writer", "pred_label": "__label__POS", "pred_score_pos": 0.8915457725524902}
{"content": "Aims: Sacubitril/valsartan (SV) reduced heart failure hospitalization and cardiovascular mortality compared with enalapril in the Prospective Comparison of ARNI with ACE-I to Determine Impact on Global Mortality and Morbidity in Heart Failure trial. However, this trial excluded patients with end stage of renal disease (ESRD); thus, the efficacy and safety of SV in heart failure with reduced ejection fraction (HFrEF) with ESRD remains uncertain.Methods and results: We retrospectively analysed the clinical and laboratory data of 501 HFrEF patients who administered with SV from March 2017 to April 2019 in a single tertiary university hospital. A total of 23 HFrEF patients with ESRD on dialysis [58.3% non-ischaemic heart failure; left ventricular ejection fraction (LVEF): 29.7 ± 4.4%] were included in this study. At baseline and follow-up visit, we evaluated cardiovascular biomarkers such as high-sensitive troponin T (hsTnT), soluble ST2 (sST2), echocardiographic parameters, and clinical and adverse events. The mean dose of SV was 90 ± 43 mg/day at baseline and 123 ± 62 mg/day at last follow-up (follow-up duration: median 132 days). The level of hsTnT was significantly reduced from 236.2 ± 355.3 to 97.0 ± 14.0 pg/mL (P = 0.002), and the sST2 level was significantly reduced from 40.4 ± 44.0 to 19.6 ± 14.1 ng/mL (P = 0.005). LVEF was significantly improved from 29.7 ± 4.4% to 40.8 ± 10.4% (P = 0.002). During the follow-up, up-titration, down-titration, and maintenance of SV dosing were observed in 7 (30%), 5 (21.7%), and 11 patients (47.8%), respectively. SV down-titration group had adverse events including symptomatic hypotension (systolic blood pressure <100 mmHg) (n = 4) and dizziness (n = 1), but they did not discontinue SV therapy.Conclusions: We found that SV could safely reduce the hsTnT and sST2 levels and improve LVEF in HFrEF patients with ESRD. As far as we know, this is the first study to show the efficacy and safety of SV in HFrEF with ESRD on dialysis. Larger prospective, long-term follow-up study should be warranted.", "pred_label": "__label__POS", "pred_score_pos": 0.7301443815231323}
{"content": "Empirically based analysis of households coping with unexpected shocks in the central Himalayas\nPublikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt\nClimate change may significantly impact the large number of households in developing countries depending on agricultural production, not least through changes in the frequency and/or magnitude of climatic hazards resulting in household income shocks. This paper analyses rural households’ responses to past experiences of and future expectations to substantial and unexpected negative and positive agricultural income shocks. Empirical data is derived from an environmentally-augmented structured household (n = 112) survey in the high mountains of central Nepal. Multinomial logit regression, using data on rural household demographics, assets (agricultural land, livestock), value of other assets such as furniture, bicycles, and agricultural implements, and income sources showed that household coping choices are determined by opportunities to generate cash. We argue that public policies should enhance the ability of rural household to generate cash income, including through environmental products.\nOriginalsprog Engelsk Tidsskrift Climate and Development Vol/bind 11 Udgave nummer 7 Sider (fra-til) 597-606 Antal sider 10 ISSN 1756-5529 DOI Status Udgivet - 2019 Det tidligere LIFE Forskningsområder\nID: 208571419", "pred_label": "__label__POS", "pred_score_pos": 0.5051435232162476}
{"content": "Different work facilities require varied interpersonal attitudes. Some workplaces need team players who constantly interact with one another and collaborate for the good of the organization. Others include offices that let employees concentrate on their work without interruptions.\nCultivating the right kind of work atmosphere can be difficult, so it might be necessary to turn to solutions such as custom software development. When webinars or training programs instruct employees on how to communicate with coworkers, there is no excuse for ignoring those guidelines. This is particularly useful for workers who have not become accustomed to certain types of workplaces and might be uncomfortable with their new cultures.\nFor instance, a stressful environment where employees have large individual daily workloads may emphasize civility and respect. If new hires aren't accustomed to this kind of setting, they can take a brief interpersonal relationship course. This use of application software development is a great example of how eLearning can be tailored to meet a company's specific training needs.Develop specialized approaches to workforce education to alleviate problems among workers before they begin to avoid employee disputes.\nContact Christy Beiermann at cbeiermann@csesoftware.com or 309.670.7595 and ask for an eLearning demo today!", "pred_label": "__label__POS", "pred_score_pos": 0.842684805393219}
{"content": "Governance QualityScore global coverage comprises of approximately 6,000+ companies in 30 markets, aligning with local market indices, including constituents of the U.S. Russell 3000, Canadian S&P/TSX Composite, STOXX600, S&P/NZX 50, S&P/ASX 300, JPX-Nikkei 400, and the main European local market indices including the UK FTSE All-Share (ex-investment trusts.)\nGovernance QualityScore also includes widely held companies in ISS ESG’s coverage universe for Brazil, China, Hong Kong, and India. The term “widely held” refers to companies that ISS ESG designates as such based on their membership in a major index and/or the number of ISS ESG clients holding the securities.\nISS ESG conducts an annual review to determine opportunities to expand our global coverage to meet the needs of investors globally.\nGovernance QualityScore uses a numeric, decile-based score that indicates a company’s governance risk relative to their index or region. A score in the 1st decile (QS:1) indicates relatively higher quality governance practices and relatively lower governance risk, and, conversely, a score in the 10th decile (QS:10) indicates relatively higher governance risk. Companies receive an overall QualityScore and a score for each of four categories: Board Structure, Compensation/ Remuneration, Shareholder Rights, and Audit & Risk Oversight.\nThe Governance QualityScore methodology focuses on the qualitative aspects of governance, including global governance standards and alignment with ISS voting policy in each region.\nISS ESG’s annual methodology review ensures that the methodology remains in step with the ISS benchmark policies as they adapt to reflect developments in regulatory and market practice.\nUse ISS ESG’s proprietary DataDesk platform for insight into a company’s corporate governance structures, quick drill-downs into particular areas of concern, and deep dives into underlying governance data.\nConnect your internal platform to the Governance QualityScore API to directly access Profiles and drill into the key risks, to easily bring governance insight into investment decisions and proxy voting processes.\nEasily ingest the files through your own internal processes and highlight scores within internal workflow platforms.\nGovernance QualityScore company profiles are available through Open:FactSet and FactSet’s research manager, while the pillar score and the category scores are accessible in the universal screener and MS Excel add-in.\nAccess to the search function is temporarily unavailable as ISS begins the QualityScore launch process. Updated scores will be available beginning November 21st.", "pred_label": "__label__POS", "pred_score_pos": 0.6229760646820068}
{"content": "Rituals are symbolic actions. In the context of LessWrong, it's significant that many rituals have some impact on your cognition, which makes them appropriate to be careful with. Nonetheless, some LessWrongers have worked to explore the space of ritual through a rationalist lens.\nIt's a bit tricky to define. The book Secular Wholeness notes:\n... There’s a hazy boundary between the words “ritual,” “habit,” and “custom.” I think the difference between a ritual act and a habitual one lies inawareness and assent. An act becomes a ritual for you when you perform it with conscious awareness of its symbolic and emotional meaning, and with willing assent to those meanings. Unless you act with both awareness and assent, your act is merely a habit (if it is unique to you) or a custom (if you share it with others).", "pred_label": "__label__POS", "pred_score_pos": 0.996821403503418}
{"content": "Abstract\nBiliary strictures are frequently encountered in clinical practice. The determination of their nature is often difficult. This study aims to systematically evaluate the efficacy and safety of the second generation of digital single-operator cholangioscopy (SpyGlass DS, DSOC) in indeterminate biliary strictures (IBDS) through biopsies. All relative studies published in Medline, the Cochrane Library, Web of Science, and EMBASE were included. The diagnostic tests for IBDS were compared to the surgical histology, autopsy, or long-term clinical follow-up. The methodological quality of the included studies was evaluated by the Quality Assessment of Studies of Diagnostic Accuracy Included in Systematic Reviews (QUADAS-2). A total of 11 studies, which involved 356 patients diagnosed through biopsies, were included. The pooled sensitivity, specificity, positive likelihood ratio, negative likelihood ratio and diagnostic odds ratio were 0.74 (95% CI: 0.67-0.80), 0.98 (95% CI: 0.95-1.00), 10.52 (95% CI: 5.45-20.32), 0.31 (95% CI: 0.23-0.41), and 65.18 (95% CI: 26.79-158.61), respectively. The area under the curve (AUC) was 0.9479, and the pooled adverse event rate was 7%. The sensitivity and specificity in the heterogeneity analysis were I2 = 48.1% and I2 = 25.4%, respectively. SpyGlass DS is a safe and effective technique for IBDS. However, future randomized trials are needed to determine optimal number of biopsies.", "pred_label": "__label__POS", "pred_score_pos": 0.943335771560669}
{"content": "Unfortunately, canceling out of fear due to political unrest is not a covered reason to cancel a trip under Trip Cancellation policies.\nWhile the ongoing unrest between the U.S. and Iran may raise concerns of retaliation against U.S. residents traveling in Europe, fear of traveling is never a covered reason to cancel a trip. Only travelers who purchased the Cancel For Any Reason upgrade can be partially reimbursed to cancel their trip because they don’t want to travel.\nIn order to be eligible for Cancel For Any Reason, a traveler must purchase their policy within 14-21 days of making their initial trip payment, and must insure 100% of their prepaid and non-refundable trip costs. This benefit allows travelers to cancel for a reason not otherwise covered by their policy, such as fear, however it will typically increase a policy’s premium by roughly 40%, and only reimburses up to 75% of their trip cost.\nThis information is time sensitive and may vary by policy. If you have questions about a specific policy. please contact us directly at 800-240-0369. Our customer service representatives are available from 8am to 10pm ET, seven days a week, and are delighted to help!", "pred_label": "__label__POS", "pred_score_pos": 0.6818288564682007}
{"content": "The toxicology minor at Nazareth College is designed for students who are interested in learning more about how the chemicals we're exposed to through our air, water, food, and other sources affect our health. It is one of only a dozen toxicology minors in the U.S. The toxicology minor suits students interested in many fields, such as the life and health sciences, public health, sociology, anthropology, public policy, economics, and law.\nAnne Pysnik '15 researched phytoremediation — using plants to remove toxins — with professors at Nazareth, while studying environmental science and toxicology. She secured a competitive internship with the Centers for Disease Control and Prevention in Atlanta, looking into titanium dioxide and tracking tasks for work on the Ebola virus.", "pred_label": "__label__POS", "pred_score_pos": 0.9501612186431885}
{"content": "Abstract\nSynchronicity experiences (SEs) are defined as psychologically meaningful connections between inner events (e.g. thought, dream or vision) and one or more external events occurring simultaneously or at a future point in time. There has been limited systematic research that has investigated the phenomenology of SEs in therapy. This study aimed to redress this by exploring the process and nature of such experiences from the perspective of the practitioner. Semi-structured face-to-face interviews were conducted with a purposive sample of nine practitioners who reported SEs in their therapeutic sessions (three counsellors, three psychologists and three psychotherapists), and focused on how participants make sense of their experiences of synchronicity in therapy. Interpretative phenomenological analysis was used to identify three superordinate themes: sense of connectedness, therapeutic process, and professional issues. Findings suggest that SEs can serve to strengthen the therapeutic relationship and are perceived as useful harbingers of information about the therapeutic process, as well as being a means of overcoming communication difficulties, as they are seen to provide insights into the client’s experiencing of themselves and others, regardless of whether or not the SE is acknowledged by the client or disclosed by the therapist.\nKeywords Interpretative phenomenological analysis meaningfulcoincidence practitioner synchronicity therapeutic process therapeutic relationship", "pred_label": "__label__POS", "pred_score_pos": 0.7521743178367615}
{"content": "Approximately 100 Swiss banks have agreed to participate in the Department of Justice’s\nProgram for Non-Prosecution or Non-Target Letters for Swiss Banks (the “Program”), which requires participant banks to provide specific information concerning foreign bank accounts held by U.S. taxpayers. As a result, U.S. taxpayers who have not disclosed foreign accounts in such banks could have their information provided to the IRS. These taxpayers are at risk of criminal prosecution, or at a minimum, risk being subject to significant civil penalties for failure to disclose such offshore accounts.\nTo gain immunity from prosecution under the Program, the banks participating in the Program generally must pay penalties to the U.S. government based on the value of the undisclosed accounts of U.S. taxpayers. Generally, these penalties will be reduced for accounts that are reported by their accountholders under the IRS’s Offshore Voluntary Disclosure Program (“OVDP”). As a result, Swiss banks participating in the Program have been contacting their current and former U.S. account holders and urging them to enter the OVDP in an effort to reduce their own monetary exposure. The disclosure by the banks of U.S. accountholder information increases the risk accountholders face because they will be unable to enter the OVDP once their information has been disclosed to the IRS. Note that the failure to disclose foreign accounts in any offshore bank, even in those banks that are not covered by the Program, produces a significant risk to the U.S. taxpayer of civil and potentially criminal action by the U.S. government.\nTaxpayers can participate in the OVDP by requesting entry into the program from the IRS. Only in limited circumstances will entry be denied. The OVDP provides a way to comply with U.S. tax laws and bring finality to the taxpayer’s noncompliance, including the taxpayer’s ultimate liability, without risk of criminal prosecution. Taxpayers who are accepted into the OVDP are required to amend their income tax returns for the prior eight years and pay taxes, interest and potential penalties on any previously unreported income from the foreign accounts. Taxpayers must also report certain information on their foreign bank accounts held at any time during the prior eight years and pay a penalty of 27.5% on the highest balance in those accounts.\nTaxpayers who continue to fail to report foreign bank accounts and choose not to participate in the OVDP may face criminal prosecution for tax evasion as well as substantial penalties well in excess of those imposed in the OVDP. As indicated, if the taxpayer’s foreign bank accounts are disclosed by any offshore bank, the taxpayer will be unable to participate in the OVDP and the risk of U.S. government action against such taxpayer should increase.\nIndividuals with questions about the reporting requirements for foreign bank accounts, assets or entities, or who are considering using the OVDP, should consult experienced tax counsel to understand the benefits and risks. Unlike communications with an attorney, communications with accountants and other financial advisors are not privileged and may have to be disclosed to the IRS. Therefore, any individual considering the ODVP should consult a tax lawyer prior to making any disclosures to their accountants or other financial advisors. If you have any questions, feel free to contact Damian Hovancik at 404.873.8518.\nTo review the entire document and formatting for this alert (e.g., footnotes), please access the original below:", "pred_label": "__label__POS", "pred_score_pos": 0.8057307004928589}
{"content": "Press briefing highlighted two successful projects — one K12 school and one university — where Danfoss technologies helped to address existing challenges and improve energy efficiency.\nDanfoss recently hosted its 23rd annual press conference during the 2018 AHR Expo in Chicago. The briefing focused on how the company is “Engineering Tomorrow” — specifically, how Danfoss is helping the industry to address the common challenges of building owners through engineering strategies and innovative solutions.\n“Innovation remains a cornerstone of our brand,” emphasized John Galyen, president, Danfoss North America. “Around the world, we continue to invest heavily in research and development each year. In North America alone last year, we opened a new Application Development Center in Tallahassee, Florida, to support the development of next-generation chillers and rooftop units, expanded our production of plate and frame heat exchanger capabilities, and established a new production facility in Utica, New York, to package silicon carbide power modules that will help meet the demand for smaller, faster, and more efficient devices like those used in utility-scale solar inverters and data centers.”\n“These investments enable us to prepare today for the trends of tomorrow,” he said. “We believe it is through innovation that we can be successful in meeting the industry’s and our customers’ challenges.”\nEngineering Tomorrow: Solutions for commercial buildings\nFor building owners, these challenges include achieving design efficiency, degradation of efficiency, system reliability, and occupant comfort.\n“The solutions to these challenges can be summarized under a lifecycle systems approach,” said Jonathan Holloway, strategic marketing manager for Danfoss North America, in his presentation.\nHe explained that:\nTo address the performance gap between design efficiency and installed efficiency, industry needs to start by designing for system interdependencies; apply smart, connected products; and ensure quality installation by skilled technicians — and coordinate all aspects through modern construction techniques like Building Information Modeling (BIM). Solutions to address degradation include proactive and adaptive systems to correct issues immediately. Sustaining efficiency should also be part of the design process, where a proactive approach to eliminate potential efficiency detractors and adaptive systems that reduce manual maintenance can deliver lifecycle results. Downtime costs are rising, but deferred maintenance with limited system data is the norm. High quality, reliable components — built into smart systems with continuous monitoring — can strengthen the chain and ensure reliable operations. Ensuring occupant comfort is critical for job performance; tight temperature and humidity control are vital and variable speed systems can help to achieve these objectives.\n“There are many technologies, products, and processes that come into play to address these challenges,” he said, “but it requires a business ecosystem and modern construction methods to move forward.”\nTo emphasize the opportunity for commercial buildings to address challenges through existing technologies, the press conference showcased two successful projects where Danfoss solutions were deployed to achieve notable results.\nIn Pensacola, Florida, where the weather is warm and extremely humid, recently-rebuilt A.K. Suter Elementary School has become Escambia County School District’s — which is home to 31 elementary schools alone — most energy-efficient school. Roger McGraw, ECSD’s mechanical engineer, emphasized the importance of the role Danfoss AB-QM™ pressure independent control valves and Danfoss Turbocor® compressors played in the construction of school’s high-efficiency HVAC plant, citing truly balanced flows throughout the entire operating range of the system, high efficiency at part-load conditions, and other benefits like reduced maintenance and sound as critical factors. The efficiency contribution has been so significant, in fact, that ECSD has seen a reduction in energy costs of 24 percent, or more than $2 million annually.\nIn Wilmington, North Carolina, the University of North Carolina Wilmington’s Center for Marine Science is located only 100 yards from the Intracoastal Waterway, causing heat and humidity challenges for its MARBIONC research laboratory. Steve Sharpe, UNCW’s energy manager, noted that key challenges included reliability — especially considering the millions of dollars invested in research and experiments — and a campus-wide initiative to reduce energy consumption. But, thanks in part to two 750-ton SMARDT water-cooled chillers utilizing 10 total Danfoss Turbocor® compressors, the lab’s chiller plant has been able to achieve outstanding part-load efficiencies and remarkable reliability. Over three years, the plant ran for more than 20,000 hours and produced nearly 6 million tons of cooling, but its average annual plant efficiency was just 0.556 kW/ton — significantly less than a baseline ASHRAE plant’s expected efficiency of 1.038 kW/ton, resulting in a simple payback time of less than three years.\n“Successful projects like these are possible through the ongoing investment Danfoss continues to make in technologies — as well as in the close collaboration with our customers to bring reliable, innovative solutions to the market to meet future challenges today. Together, we are working to Engineer Tomorrow,” Galyen concluded.", "pred_label": "__label__POS", "pred_score_pos": 0.777809202671051}
{"content": "Building data-driven resilience in our agrifood supply chains.\nThis campaign is identifying what parts of our agrifood supply chains are most vulnerable to shocks and stresses and where R&D and data and digital interventions can deliver the greatest return on investment.\n\"We need to proactively invest in implementing strategies that leverage digital and data interventions to enhance the sector's underlying resilience.\"\nThe\nAgriFood Supply Chain Resilience report was compiled in collaboration with KPMG Australia and Food Agility CRC. It looks across six key supply chains: grains, red meat, dairy, horticulture, wine and seafood. It identifies the inherent stresses and what happens when shocks occur, then goes further to determine which mitigation strategies could have the greatest impact.\nThis campaign aims to put data-driven tools in the hands of agribusinesses and communities to help them make long-term decisions for resilience, including profitability, sustainability and risk.\n\"If you're effective in sharing knowledge then outcomes by default are enhanced profits, business trust and stronger communities.\"\nThis campaign aims to digitally connect supply chains, creating end-to-end data flows that build trust and flexibility to manage shocks, grasp opportunities and pivot into new business models.\n\"It's not until all parts of the supply chain are connected with data flowing throughout, that we will see the true potential of our agrifood system.\"", "pred_label": "__label__POS", "pred_score_pos": 0.9996252655982971}
{"content": "2015 年 10 巻 2 号 p. 288-298\nIn the flood prone areas of Bangladesh, local people have adapted to flooding. Essentially, properties are protected against flooding by constructing villages in the highlands on natural levees, while using lowlands as agricultural fields during the dry season. It remains to spread flood inundation condition and exempts the necessity of strengthening measures against flooding. This study aims to clarify the status of self, community, and public assistance for flood disasters in flood prone areas of Northeast Bangladesh based on a questionnaire survey. We extracted similarities and differences between local people’s flood responses by comparing our findings to those of a similar study on a 2006 flood in the Sendai River Basin, Japan. The effects of preventive flood mitigation measures such as selection of house location are quantitatively confirmed. Maximum inundation depth and duration for houses is approximately 10% less than that for agricultural fields. The study reveals that both areas have evacuation activities, although factors motivating evacuation differ.\nこの記事は最新の被引用情報を取得できません。", "pred_label": "__label__POS", "pred_score_pos": 0.9624517560005188}
{"content": "Clinical assessment of pharyngeal airway has not prevailed in dogs. Based on the findings that the craniocervical X-rays and fluoroscopy in 89 consecutive non-brachycephalic dogs with upper airway signs indicated caudal displacement of the larynx, excessive dorsal pharyngeal wall, descent of the tongue, and soft palate unified with the dorsal pharyngeal wall, we defined pharyngeal airway obstruction syndrome (PAOS) and reviewed clinical features, treatment, and outcome of PAOS. In this study, the median age of affected dogs was 9 years. Pomeranian (odds ratio, OR=18.7) and Yorkshire Terrier (OR=3.7) were significantly predisposed. The most common symptom was chronic cough (n=32), the representative signs were obese (BCS>4/5, n=58), snoring(n=53), tachypnea(n=52), sleep disordered breathing(n=40), persistent productive cough(n=39), dry cough(n=38). The most frequent final diagnosis was tracheal collapse (n=29), while 22 percent of these 89 dogs had no conventional diagnosis. In 46 dogs, body weight loss was instructed, and any upper airway signs significantly improved until 3 months in 86.7% of these dogs. Some severely affected dogs had persistent sleep apnea (n=11) or noncardiogenic pulmonary edema(n=9) on admission. In the latter, the 60-day survival rate was 66.7 %. PAOS is distinguished by individual pharyngeal structure, despite of breeds or the skull shapes. Clinician must identify PAOS and instruct body weight loss to pet owners as early as possible if the affected dog is obese.\nA 12-year-old dog with anorexia, lethargy, fever, and cough was referred to our hospital. Blood tests revealed a low platelet count and high levels of C-reactive protein (CRP). The detection of Anaplasma phagocytophilum (A. phagocytophilum) DNA in the blood, the positive result for antibodies to A. phagocytophilum, and the presence of morulae within granulocytes in the peripheral blood confirmed the diagnosis of canine granulocytic anaplasmosis. Phylogenetic analysis of gltA and groEL gene revealed that the strain detected in this study and A. phagocytophilum previously reported in Japan were closely related. However this is the first report of canine granulocytic anaplasmosis in western Japan. A. phagocytophilum infection may also occur in non-epidemic regions of Japan.\nThe objective of this study was to assess correlation between the changes in the central venous pressure (CVP) and hematocrit (HCT) to estimate blood loss in dogs during hepatectomy. Medical records of dogs who underwent elective hepatectomy to treat hepatic mass lesion at the Veterinary Teaching Hospital, Nippon Veterinary and Life Science University from August 2017 to July 2018, were retrospectively investigated. Data of five client-owned dogs (4 females and 1 male) aged 10-13 years (average age, 12.2 years) were included in this study. The parameters recorded during hepatectomy included esophageal temperature, heart rate, respiratory rate, arterial blood pressure, hemoglobin oxygen saturation, end-tidal carbon dioxide, end-tidal isoflurane, volume of lactated Ringer's solution, and CVP. Maximum, minimum, and mean values of CVP were investigated. Preoperative and postoperative HCT levels were 34.0 ± 2.4% and 20.0 ± 3.1%, respectively, suggesting that the HCT levels significantly reduced after hepatectomy (p=0.0033). Pearson’s correlation coefficient between maximum changes in CVP and HCT levels was 0.8792 (p=0.0495). No significant correlations were identified among other variables. In this study, CVP influenced changes in HCT levels associated with bleeding in dogs undergoing hepatectomy.\nOral low-dose chemotherapy using a combination of etoposide, Chlorambucil, filocoxib, and piroxicam was used to perform adjuvant chemotherapy on four dogs with grade 2 or 3 splenic hemangiosarcoma. The survival times of the four cases were 307, 248, 285, and 309 days, respectively. This study highlights an alternative adjuvant chemotherapeutic modality for canine splenic hemangiosarcoma. However, further investigations in a larger number of cases are desired.", "pred_label": "__label__POS", "pred_score_pos": 0.729964017868042}
{"content": "Longitudinal four-dimensional mapping of subcortical anatomy in human development. Raznahan A., Shaw PW., Lerch JP., Clasen LS., Greenstein D., Berman R., Pipitone J., Chakravarty MM., Giedd JN.\nGrowing access to large-scale longitudinal structural neuroimaging data has fundamentally altered our understanding of cortical development en route to human adulthood, with consequences for basic science, medicine, and public policy. In striking contrast, basic anatomical development of subcortical structures such as the striatum, pallidum, and thalamus has remained poorly described--despite these evolutionarily ancient structures being both intimate working partners of the cortical sheet and critical to diverse developmentally emergent skills and disorders. Here, to begin addressing this disparity, we apply methods for the measurement of subcortical volume and shape to 1,171 longitudinally acquired structural magnetic resonance imaging brain scans from 618 typically developing males and females aged 5-25 y. We show that the striatum, pallidum, and thalamus each follow curvilinear trajectories of volume change, which, for the striatum and thalamus, peak after cortical volume has already begun to decline and show a relative delay in males. Four-dimensional mapping of subcortical shape reveals that (i) striatal, pallidal, and thalamic domains linked to specific fronto-parietal association cortices contract with age whereas other subcortical territories expand, and (ii) each structure harbors hotspots of sexually dimorphic change over adolescence--with relevance for sex-biased mental disorders emerging in youth. By establishing the developmental dynamism, spatial heterochonicity, and sexual dimorphism of human subcortical maturation, these data bring our spatiotemporal understanding of subcortical development closer to that of the cortex--allowing evolutionary, basic, and clinical neuroscience to be conducted within a more comprehensive developmental framework.", "pred_label": "__label__POS", "pred_score_pos": 0.650086522102356}
{"content": "A Skilled Family Law Firm Guiding You In Child Support Matters\nChildren deserve to be loved and properly cared for during their lives. When any or both of those principles are ignored, children likely face challenges for years to come. Some of those challenges are financial ones that surface in any household, including those run by a single parent or divorced parent.\nChild support payments go a long way toward helping single and divorced parents raise their families. Because the financial responsibility of raising a child falls on both parents, child support can be a crucial part of the equation in certain scenarios. My law office, Cynthia M. Pyfrom, P.A., in Boynton Beach, Florida, is an effective legal ally that understands family law.\nLeading The Way And Taking Action For You\nAttentive and prepared, I will discuss legal strategies with you in securing fair child support payments. Once child support is awarded, I will help you obtain it. One way is by garnishing the wages of the child’s other parent. If that other parent neglects his or her part of the agreement by failing to pay child support, I will pursue swift and legal enforcement actions against him or her.\nWhen things change financially, I will help you in modifying child support agreements. The modification route surfaces at times when:\nA parent receives a significant income boost, leading to the custodial parent receiving more money. A parent experiences a loss of income due to unemployment, leading to a temporary decrease in child support payments. A parent remarries, potentially leading to smaller child support payments A child’s needs change in areas such as increased costs education and health care.\nRaising a child alone is not easy, but your love for your child will go a long way, and so will fair child support payments. Let me help you.\nSchedule An Appointment Now\nYou are legally entitled to child support payments to help raise your children. As a skilled family law attorney, I can provide the insight and direction you need. I am Cynthia M Pyfrom, in Boynton Beach, Florida. I care about my clients and will protect them and help them reach their goals. Contact me by filling out this online form or calling 561-354-0403.", "pred_label": "__label__POS", "pred_score_pos": 0.8576160073280334}
{"content": "This years’ World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (WCO-IOF-ESCEO) is set to take place virtually on 20-23 August. While it is not the ‘live’ stage many had initially anticipated, the virtual congress is a fantastic opportunity to connect with the osteoporosis community and share insights into the latest advances in bone health from around the world.\nIn today’s current climate, the importance of continuing to connect from afar extends beyond congresses. Recently, UCB announced a new collaboration with the International Osteoporosis Foundation (IOF) to support its Capture the Fracture\n®\nprogram which aims to combat the global public health burden of osteoporosis by reducing the incidence of hip and vertebral fractures by 25% by 2025.\nOsteoporosis is a serious chronic condition that weakens bone over time, making them thinner and more likely to break. We are fortunate though, that there are steps patients and healthcare providers can take to reduce fracture risk. Despite these resources, even after an osteoporosis-related fracture, approximately, 80% of individuals at high risk are still not identified or treated. Capture the Fracture, a global IOF initiative, now supported by UCB and Amgen and in collaboration with the University of Oxford, aims to proactively implement post-fracture care (PFC) coordination programs in hospitals and healthcare systems to help patients prevent subsequent fractures due to osteoporosis.\nThis partnership also welcomes collaboration from existing fracture prevention coalitions on international, regional, and national levels to drive fracture prevention policy change and prioritization. Additional aims of the partnership include developing and implementing efficiencies and best practice sharing across PFC program sites, creating digital platforms to track and share PFC effectiveness, and providing virtual and in-person mentorship and learning opportunities for healthcare providers.\nBy continuing to connect, partner and collaborate with organizations and experts around the world, even virtually, UCB hopes to tackle a significant healthcare issue that has been overlooked for too long, and deliver better support and outcomes for people living with the osteoporosis.\nFor more information about Capture the Fracture, please visit http://www.capturethefracture.org\n.", "pred_label": "__label__POS", "pred_score_pos": 0.9996681809425354}
{"content": "Schooling and wage income losses due to early-childhood growth faltering in developing countries: national, regional, and global estimates\nThe growth of >300 million children <5 y old was mildly, moderately, or severely stunted worldwide in 2010. However, national estimates of the human capital and financial losses due to growth faltering in early childhood are not available. The researchers quantified the economic cost of growth faltering in developing countries.", "pred_label": "__label__POS", "pred_score_pos": 0.9238726496696472}
{"content": "by Sahil Chopra\nLanguage is the medium by which we interact with culture, express our ideas, and maintain our rights. Without “language access”, i.e. the ability to convey one’s thoughts effectively and understand others correctly, one is disempowered altogether. At a societal level this can lead to systemic inequality, whether intentional or not; and one of the places where this is most evident is the court system.\nThis Autumn, I’m one of the 25 students enrolled in Stanford’s Design for Language Access, a course initiated by the Stanford Legal Design Lab to investigate and advise how state courts may better serve Californians entering the legal system, who either do not speak or have limited proficiency with English.\nAs the Judicial Council of California’s Strategic Plan for Language Access in California Court details, 40% of Californians speak non-English languages at home, 200+ languages and dialects are spoken by Californians as a whole, and approximately ~20% of Californians have English language limitations. Going to court is always a stressful experience, as the impetus to seek court help is often a difficult circumstance itself. Coupling the weight of the incident with the inability to communicate and properly resolve your issue only magnifies the stress incurred by the individual. Moreover, it may be difficult to properly resolve one’s legal issue and receive the proper access to one’s legal rights if they are unable to effectively communicate with lawyers, clerks, and judges within the judicial branch. Thus, “language access”, as the Judicial Council of California titles it, is a critical issue that we must address in order to ensure and fair and equitable legal proceedings.\nPersonally, I have no prior background with judicial systems. I’m a computer scientist by training, completing my BS/MS with concentrations in Artificial Intelligence and Human Computer Interaction – focusing a bulk of my research in cognitive science and natural language processing. But that’s where the diverse experience of my classmates come in. We are lawyers, teachers, designers, business students, and computer scientists — all hoping to better understand this space and offer a different perspective.\nOver the next nine weeks, we shall apply the fundamental principles of “Design Thinking” to first observe and interview individuals going through the court system and then hypothesize, prototype, and test potential strategies that may provide better language access to millions of Californians. Our class will culminate in a list of possible solutions and implementations which the California courts may consider as potential avenues by which the state can improve language access at scale. Additionally, we shall be evaluating a pilot program that California courts is running in San Jose, where tablets with Google Translate are being employed to help ease communication between non-English-speaking clients and English-speaking court staff.\nStay tuned to learn more week-by-week about our journey to help provide better language access to Californians!", "pred_label": "__label__POS", "pred_score_pos": 0.8534504175186157}
{"content": "The\nNew York Times opinion piece by David Brooks, titled “The Neural Buddhists,” drives a wedge between mystical and “revealed” religions by citing recent philosophical and scientific scholarship. Brooks suggests that neuroscience (including psychology) poses a considerable challenge to religions that emphasize divine law or revelation. Brooks is right to predict that neuroscience will profoundly affect our culture’s thinking. Neuroscience forces us to revise our concept of self. And I agree that the investigation into universal moral intuitions raises interesting questions about the emergence of religion. My guess is that its most significant cultural contribution will be, simply, increased happiness.\nHowever, Brooks unadvisedly argues that neuroscience will affect metaphysics. He claims that neuroscience can validate sacred experiences and that it can show us that these experiences are the same as God. “Scientists whose beliefs overlap a bit with Buddhism,” Brooks writes, will be the primary challengers of revealed religions. The implication is that neuroscience has found a way to transcend the practical and philosophical boundaries within which it operates. This has not occurred. Moreover, my years of reflecting on brain and behavior have made me deeply appreciate how scientifically intractable metaphysical propositions are. While individuals should be encouraged to form their own private opinions, there is no need to adopt religious intolerance in the name of neuroscience. Below I share a few reasons why I think this is the case. Each speaks to the difficulty neuroscience has characterizing the ultimate nature of reality.\nFirst, there is Brooks’s claim that people are equipped to “to have moments of elevated experience when they transcend boundaries and overflow with love.” At present, neuroscience is poorly positioned to evaluate this. The brain’s complexity is a tremendous practical constraint on neuroscience’s reach. New kinds of measurement bring about advances in neuroscience: the more sensitive, reliable, and physically interpretable a measure, the better. Much of the challenge in developing new measures is finding an interpretable signal buried in all the complexity. We do not have a sensitive, reliable, and physically interpretable measurement of “transcendence” or related phenomena.\nThe brain is active from early in development until death. It would be remarkable if there were no brain activity during a presumed mystical state. A challenge confronting neuroscientists who study mystics is determining which part of observed brain activity relates to the subjectively meaningful part of a mystical state. Brain activity may arise from performance anxiety, daydreaming, or attention to the endeavor at hand. One way to evaluate this would be to correlate brain activity with real-time ratings of subjective mysticism. We could ask someone who is attempting to cultivate such a state to adjust a knob every few seconds according to the intensity of the experience. However, doing so might interfere with the state.\nLate night television comedian David Letterman occasionally does a sketch called “Is This Anything?,” where he and sidekick Paul Schaffer jokingly debate whether some bizarre stage performance is “nothing” or “something.” By analogy, neuroscience has confirmed that mystically oriented practices are “something.” However, as in the comedy sketch, “nothing” isn’t really an option.\nWe can currently evaluate comparatively mundane aspects of mystically oriented practices. Are practitioners subsequently less distracted or anxious? Does a given practice increase antibody titers, or decrease inflammation? Are practitioners better at spatial reasoning or math? Such things are measurable. Some such findings may prove useful to society, but will likely not take a side in the worldview debates.\nThere are more deeply philosophical reasons why neuroscience will stay out of metaphysics. For instance, neuroscience may never solve the age-old philosophical puzzle of how primal our subjective experience is. This is my second disagreement with Brooks. He says, “God can best be conceived as the nature one experiences at [mystical] moments, the unknowable total of all there is.” I am sure that some people have these deeply meaningful experiences. However, it is pointless for neuroscience to update a term (God) that in conventional parlance refers to the ultimate power that rules the universe.\nIt is true that our access to the “real” world, meaning the objective world “out there” that science purports to study, is through our subjective awareness. Some proponents of the ancient Greek school of Solipsism have maintained that the only thing that is knowable is this subjective awareness. To cite one recent popular example: how can I possibly prove that I am not part of a video game? The blockbuster movie\nThe Matrix portrayed a world whose inhabitants were unknowingly part of a fictitious computer-generated world, a world piped straight to their brains. A Matrix scenario challenges universality and other assumptions of physical law. Non-universality opens an infinite number of alternative options for how the universe works. It is easy to imagine a future interactive video game in which the game engine treats each player differently, with a strain of fundamentalism being “true” for some, and quantum electrodynamics being “true” for others.\nSolipsism has vexed philosophers throughout history. Most have thought it unlikely. However, most also have thought it causes trouble. One critic, the philosopher Arthur Schopenhauer spoke of it as an irremediable evil. I, too, feel uncompelled by solipsism. Because I think about the chasm between introspective awareness and the physical world, however, I am sensitive to the trouble it causes.\nThe Matrix illustrates just how poorly positioned one is to see the grand design of the universe. No functional neuroimaging device, even if it is pointed at the most transcendentally devoted brain, will take us to the highest vantage point in the universe.\nNevertheless, there is promise in pointing tools at mystics’ brains. We will not find true metaphysical reality or define God. Instead, such research is an opportunity to explore something different from standard lines of inquiry, something that may cast new light on how the brain works. Resulting findings will fold into the evolving model of the nervous system. Perhaps these new understandings will benefit mental health or improve technology.\nAs for neuroscience as a whole, it will give society a lot of new material to work with. For both pragmatic and philosophical reasons, however, it is clear that Brooks granted neuroscience an undeserved authority over metaphysics.", "pred_label": "__label__POS", "pred_score_pos": 0.5761727094650269}
{"content": "As we head into prime mosquito season in North Carolina, NC State University Ph.D. student Sophia Webster outlines ways you can limit your exposure by eliminating standing water or using insect sprays.\nWebster, who conducts research in the Department of Entomology, works with\nAedes aegypti, one of the mosquitoes that can transmit the Zika virus. While concern about Zika’s presence in Florida has captured news headlines, the virus has not been found in North Carolina mosquitoes.\nPortions of b-roll provided courtesy of the CDC.\nThis post was originally published in College of Agriculture and Life Sciences News.", "pred_label": "__label__POS", "pred_score_pos": 0.6241978406906128}
{"content": "Please enjoy the following article from the Journal of Urban Affairs, available online.\nAbstract:\nThis study explores the neighborhood disparities in access to street arts festivals (SAFs) based on a case study of Chicago. The city’s street closure permit database is used to identify the locations of SAFs and examine how access to SAFs is associated with the characteristics of neighborhoods. The results show that SAFs are highly spatially concentrated and are not equally accessible from different types of neighborhoods. Specifically, access to SAFs within walking distance declines significantly as the proportions of Black, Hispanic, and elderly residents increase. A comparative analysis finds that SAFs are even less accessible than museums/art galleries from Black or Hispanic neighborhoods and areas with a higher share of elderly residents. However, neighborhood income is not a significant predictor of SAF accessibility. This study’s findings have important implications for policymakers because they suggest that SAFs further disadvantage certain types of historically underserved neighborhoods, especially Black neighborhoods, regarding arts accessibility.", "pred_label": "__label__POS", "pred_score_pos": 0.999637246131897}
{"content": "CFE Plans to Take Advantage of Natural Gas SurplusBy Cas Biekmann | Mon, 11/09/2020 - 16:30\nMexico’s state-owned energy utility CFE will sell surplus natural gas to private players through a new subsidiary, formed by CFE’s CFEnergía arm, reports BNAmericas. Other efforts to turn the surplus into a boon include launching bids to build new power producing plants and to allow exports after liquefaction. By taking such actions, CFE aims to benefit from the natural gas it is already contractually obligated to purchase from third parties but cannot use in its own power plants. The Mexican industry and natural gas liquefaction plants are likely candidates to purchase the gas.\nThe gas capacity contracts CFE signed to import its natural gas supply have faced a slew of criticism over time. President López Obrador identified seven pipeline contracts signed during the previous administration and considers them ‘unfair’ to CFE, citing its take-or-pay and force majeure clauses as problematic, reported Natural Gas Intel. By renegotiating terms with IEnova, TC Energy and Grupo Carso, CFE could save US$4.5 billion.\nNevertheless, this renegotiation is costing the state an extra US$6.84 billion over the duration of the contracts, the Superior Audit of the Federation (ASF) noted in a report that criticized CFE for its incapability to be profitable on its own. The terms of five out of seven contracts had been extended from 25 to 35 years and established a levelized rate over this period, meaning that CFE will incur in higher costs.\nCFE rejected ASF’s general criticism in a press conference last Friday, noting that it managed to lower prices during the first 25 years of the contracts, with an even lower price during the 10-year extension. BNAmericas noted that this argument was not inconsistent with ASF’s report, which focused on a wider scope than the natural gas contracts.\nEl Financiero reported that Miguel Reyes, Director of CFEnergía, also plans to launch two bids to build two further natural gas-based energy generation plants to put the surplus to good use. “We are going to launch a call in the next few days or weeks, regarding the new plants that CFE is going to build. They obviously will have natural gas as their main input,\" said Reyes.\nFurther plans Reyes mentioned to benefit from the surplus include an extension of pipelines across the country, as well as allowing for the construction of a natural gas liquefaction plant to be able to export the natural gas to Asia. Sempra Energy’s Mexican subsidiary IEnova has been working on this possibility for exports, an option now confirmed by Reyes to be highly feasible.", "pred_label": "__label__POS", "pred_score_pos": 0.5931558012962341}
{"content": "If you are a diabetic taking insulin, Medicare’s Senior Savings Model offers a broad selection of insulins at a predictable and more affordable cost through the initial coverage stage and the coverage gap stage.\nThe\nFarm Bureau Select Rx plan is participating in Medicare’s Senior Savings Model, which means members enrolled in this plan can access certain insulin products will be $35 copayment for a 30-day supply until you reach the catastrophic coverage stage.\nBeneficiaries who qualify for Medicare’s low-income subsidy already receive help on their premium and out-of-pocket costs. If you already receive a low-income subsidy, the $35 copayment does not apply\n.", "pred_label": "__label__POS", "pred_score_pos": 0.8912234902381897}
{"content": "The Coronavirus Aid, Relief and Economic Security (CARES) Act requires non-grandfathered group health plans to cover qualifying COVID-19 preventive services, including COVID-19 immunizations, without cost sharing. A final rule was issued to implement this requirement and mandate coverage within 15 business days after approval by the Advisory Committee on Immunization Practices of the CDC and adoption by the Director of the Centers for Disease Control and Prevention.\nThis coverage must be provided for both in-network and out-of-network providers during the COVID-19 public health emergency.\nEmployers that are considering whether to encourage or require employees to get a COVID-19 vaccine can look to guidance related to the influenza vaccine, including OSHA and the EEOC’s ADA and Title VII limitations, since COVID-19 specific guidance has not been issued at this time. Additionally, employers should consult legal counsel to determine whether there are unique risks to consider for their specific organization.\nPlease see our bulletins below for additional information on the vaccination coverage mandate and employer considerations for whether to require vaccination.\nPlease contact our Employee Benefits team if you have questions or need assistance.", "pred_label": "__label__POS", "pred_score_pos": 0.9802205562591553}
{"content": "There are several claims that storing plastic bottled water in hot cars can lead to cancer especially breast cancer in humans. The assertion is that the heat in the car causes the plastic bottle to leach certain chemicals into the water, which is then consumed leading to inadvertent ingestion of potential carcinogens!\nThere has been a lot of speculation surrounding the truth to these claims. Is it really a myth or fact! To determine this there must be supporting information.\nA statement from the International Bottled Water Association (IBWA) dated June 8th 2007, entitled “Science proves that plastic bottled water containers are safe under a variety of conditions”, states that there are no studies that prove this theory; instead, these allegations have been perpetuated by emails and media hype that only frighten and confuse consumers.\nFood plays a significant role in many celebrations. Stuffed turkey is a tradition at Christmas time and for our North American friends turkey is Thanksgiving.\nIt is always important to follow safe food-handling practices to prevent harmful bacteria from spreading and causing foodborne illness because cooking a home stuffed turkey can be somewhat riskier than cooking one not stuffed. If the stuffing is not cooked and handled properly, food borne illness can occur.", "pred_label": "__label__POS", "pred_score_pos": 0.9676067233085632}
{"content": "From award-winning author Ken Ginsburg comes this new work which explores an innovative idea in parenting: “The Lighthouse Parenting Strategy.”\nDr. Ginsburg’s previous work includes “Building Resilience in Children and Teens” which offers a comprehensive overview of strategies to build resilience and promote the kind of traits that lead to our children becoming happy, successful adults. This book offers a deeper dive into two fundamental questions over which parents struggle:\nHow do I give my child the unconditional love he needs to thrive, while also holding him to high expectations? How do I protect my child while also letting her learn life’s lessons? “We should be like lighthouses for our children; beacons of light on a stable shoreline from which they can safely navigate the world. We must make certain they don’t crash against the rocks, but trust they have the capacity to learn to ride the waves on their own.”\nThis book is rooted in proven concepts from the positive youth development and resilience frameworks and combines new research with expert opinion to help parents consider how to approach these toughest of questions.\nThis book is co-written by Dr. Ginsburg’s two teenage daughters, Ilana and Talia Ginsburg, and perspectives from over 500 teens are also part of this groundbreaking work.", "pred_label": "__label__POS", "pred_score_pos": 0.9628497362136841}
{"content": "Most of the prior design studies on compound split hybrids focused on the selection of optimal configurations through evaluating their performance within the physical design space, i.e., powertrain configurations. However, the authors revealed that using the compound lever for the performance analysis dramatically reduces the design space as redundant configurations exist for a single compound lever design, resulting in computational load reduction. Nevertheless, using the compound lever results in the loss of information required to realize the given configurations as these two configurations are represented by two different sets of variables. The powertrain configuration is defined by two physical design variables, i.e., gear ratios of the two planetary gears. However, the compound lever design is defined by two nonphysical design variables, α and β, which are the vertical bar lengths between the output node (vehicle) and the two motor/generators' (MG) nodes. Thus, if the compound lever is used as a design tool, the selected designs should be converted into powertrain configurations. This paper introduces an automatic methodology to generate feasible powertrain configurations for any given compound lever using generic conversion equations that express the relationship between the nonphysical design variables, α and β, and the physical design variables, gear ratios. Conversion maps relating the 252 powertrain configurations to the compound lever design space were generated, and the results confirmed that the compound lever removes the redundancy existing in the physical design space.", "pred_label": "__label__POS", "pred_score_pos": 0.8384612202644348}
{"content": "The issues around settlement, belonging, and poor relief have for too long been understood largely from the perspective of England and Wales. This volume offers a pan-European survey that encompasses Switzerland, Prussia, Belgium, the Netherlands, and Britain. It explores how the conception of belonging changed over time and space from the 1500s onwards, how communities dealt with the welfare expectations of an increasingly mobile population that migrated both within and between states, the welfare rights that were attached to those who \"belonged,\" and how ordinary people secured access to welfare resources. What emerged was a sophisticated European settlement system, which on the one hand structured itself to limit the claims of the poor, and yet on the other was peculiarly sensitive to their demands and negotiations.", "pred_label": "__label__POS", "pred_score_pos": 0.9286011457443237}
{"content": "Abstract\nAims: This study sought to evaluate how soil organic carbon (SOC) and total nitrogen (STN) stocks vary following the conversion of a deciduous natural forest (DNF) to a paddy rice farm (PRF), a seventy-year-old Pinus koraiensis monoculture (CP70), a mixed forest (MF) plantation, and a P. koraiensis monoculture resulting from the re-plantation of a portion of the CP70 attacked by bugs. Methods: Soil samples (0–30 cm) were collected from DNF, PRF, CP7, CP70 and MF in the Gwangneung experimental site located in Gyeonggi-do (South Korea), and analyzed for bulk density, pH, SOC, STN content and stocks (0–30 cm). Results: The conversion of DNF into PRF showed 23.9% SOC stocks and 54.5% STN stocks increases. However, there were no significant changes in STN or SOC stocks after DNF was reforested for seven or 70 years or when PRF was reforested to MF. Conclusions: The conversion of a DNF to a PRF increased the SOC and STN stock, which might be due to over 63 years’ fertilizations with urea and diammonium phosphate, but reforestation with a P. koraiensis monoculture for 70 years and/or mixed forest was enough time to restore SOC and STN stocks to natural levels.\nKeywords Mixed forest plantation Monoculture plantation Natural reforestation Paddy rice farm Soil organic carbon stocks ASJC Scopus subject areas Soil Science Plant Science", "pred_label": "__label__POS", "pred_score_pos": 0.7531543970108032}
{"content": "For nurses, postgraduate students, doctors, gynaecologists and colposcopists\nIARC Technical Publications 45\nEdited by W. Prendiville and R. Sankaranarayanan\n2017\nThis colposcopy manual was developed in the context of the cervical cancer screening research studies of the International Agency for Research on Cancer (IARC) and the related technical support provided to national programmes. It is thus a highly comprehensive manual, both for the training of new colposcopists and for the continuing education and reorientation of those who are more experienced. This manual offers a valuable learning resource, incorporating recent developments in the understanding of the etiology and pathogenesis of cervical intraepithelial neoplasia (CIN), as well as in colposcopy and cervical pathology.\nExpertise in performing satisfactory, safe, and accurate colposcopic examinations requires high competence in the technical, interpretive, and cognitive aspects, and the capability to develop pragmatic and effective management plans and treatment. This comprehensive and concise manual covers all these aspects and serves as a useful handbook for acquiring the necessary skills for the visual recognition and interpretation of colposcopic findings and for developing the personal and professional attributes required for competence in colposcopy.\nPDF version Overview", "pred_label": "__label__POS", "pred_score_pos": 0.5467628240585327}
{"content": "So no, White women, if this election means four more years of the atrocity in the White House, I will not embrace my oppressors when this is over. I will not gather with those who used their vote to affirm that I should remain a third class citi…\nEunice Brownlee\nBy labeling one side as \"wrong\" and the other side as \"right,\" you're failing to see the nuances of each side. It's not \"this\" or \"that,\" it's a spectrum, a continuum. When we're always looking for a \"win,\" the \"other side,\" is only strategizing for the next \"win.\" We then have the pendulum swinging wildly, which never brings about a stable society.\nChange comes not from offending one another and labeling others as \"wrong\" or \"these women.\" This is a form of violence. It's about recognizing the deep-seated issues that brought about these differences. A racist wasn't born that way, and you can't heal the systemic racism by judging others for how they were brought up. You also can't assume that \"they\" are a monolith.\nInstead, sustainable change comes when we all have a seat at the table with the aim for resolution, not \"winning.\"\nWe might feel a sense of relief when Trump leaves office, but we can't ignore the irritant that built him up. Yes, I believe Trump is the Golgothan Shit Demon (from \"Dogma\") that was raised from some of the hate in society. But responding to hate with more hate just brings about more instability, and the pendulum could easily swing back towards Trumpism if we fail to look at how we ourselves are contributing to the problem.", "pred_label": "__label__POS", "pred_score_pos": 0.8660722970962524}
{"content": "1.1 This test method covers stressing an engine oil under modern high-speed diesel operating conditions and measures the oil's deposit control, lubrication ability, and resistance to oil consumption. It is performed in a laboratory using a standardized high-speed, single-cylinder diesel engine.\n1.2 The values stated in SI units are to be regarded as standard. No other units of measurement are included in this standard.\n1.2.1 Exceptions—Where there is no direct SI equivalent such as screw threads, national pipe threads/diameters, and tubing size, or where a sole source supplier is specified.\n1.3\nThis standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety, health, and environmental practices and determine the applicability of regulatory limitations prior to use. Being an engine test method, this test method does have definite hazards that require safe practices (see Appendix X2 on Safety).\n1.4 The following is the Table of Contents:\n[This table has been removed.]\n1.5\nThis international standard was developed in accordance with internationally recognized principles on standardization established in the Decision on Principles for the Development of International Standards, Guides and Recommendations issued by the World Trade Organization Technical Barriers to Trade (TBT) Committee.", "pred_label": "__label__POS", "pred_score_pos": 0.8325021266937256}
{"content": "Many children, particularly HIV/AIDS orphans are unable to remain or continue in school. When the bread winner dies, they are left to fend for themselves.\nSome are left in the care of relatives who are struggling to keep their own immediate families from starving. Subsequently, when the relative can no longer cope, the orphans suffer most. In terms of education, typically the guardians care for their own sons and daughters only.\nThis has contributed to the increasing number of street kids roaming in the city and other towns. Many of these orphans and vulnerable children end up in child domestic labor and prostitution; other children are left in the hands of their aged grandparents who are unable to contribute much towards their wellbeing.\nSUTCHI is supporting orphans and children with special needs access education by\nproviding scholastic materials, school fees and other personal effects while promoting child participation in the fight against child rights violations.", "pred_label": "__label__POS", "pred_score_pos": 0.5439062118530273}
{"content": "On Wednesday, the House Agriculture Committee heard from agriculture, maritime, and manufacturing stakeholders voicing their concerns over the next farm bill and the future of international food aid and agricultural development.\nOn behalf of the wheat industry, Mr. Ron Suppes, a wheat grower from Dighton, Kansas, testified on food aid and a recent trip to Tanzania where he saw programs that utilized wheat.\n“In Tanzania, I saw firsthand how wheat farmers can play a significant role in international food aid programs,” Suppes said. “These programs involve a significant amount of wheat, a fact not lost on farmers with full grain bins and more wheat piled on the ground from last year’s historically high harvest. It is a year when the U.S. needs to be a world leader in helping provide for those in need with these ample supplies.\n“Food aid can also generate goodwill with other countries. By encouraging agricultural development in Tanzania, we’re ultimately spurring economic growth, which means Tanzania is more likely to be a stronger trading partner in the future. And the tangible presence of U.S. wheat in that equation is a symbol that cash can’t match.\n“U.S. commodities play a key role in helping regions unable to produce wheat and other commodities on their own due to drought, conflict or other circumstances. We have enough surplus that no one should be going hungry.\n“I commend the House Committee on Agriculture recognizing and highlighting the valuable role that the agricultural industry plays in international food aid.”\nFollowing the hearing, Chairman K. Michael Conaway (TX-11) remarked:\n“Americans are big-hearted people and eliminating food aid programs goes against our country’s longstanding philanthropic commitment. For the past 60 years, U.S. foreign assistance has benefitted millions around the world in the form of rice, wheat, and other U.S.-grown commodities. Unlike cash-based assistance, sending commodities overseas through international food aid programs not only benefits recipients, but also contributes to jobs in the U.S. agricultural, manufacturing and maritime sectors – underscoring the role these programs play in an ‘America-first’ approach to helping others. I continue to believe there is an important place for these programs, and I appreciate the input from our witnesses today.”", "pred_label": "__label__POS", "pred_score_pos": 0.5204213857650757}
{"content": "Despite remaining systemic hurdles, unprecedented media representation and access to technology are shifting the notion of power for Gen Z: This cohort is rethinking the value of centralized ideas that benefit the few; instead, embracing a more collaborative notion that empower collectives.\nEnjoying This Commentary? There's More to Love\nSubscribe to MediaVillage to receive email alerts featuring the latest content on advertising, media/TV, and marketing strategies and trends, including exclusive The Myers Report research findings.", "pred_label": "__label__POS", "pred_score_pos": 0.9998335242271423}
{"content": "Being involved in a traffic stop can be a stressful and daunting process, which may only become more challenging should allegations of impairment arise. A DUI is a serious offense that, contrary to popular belief, may not always include the consumption of alcohol. Individuals in Wisconsin may find it advisable to know the potential side effects of their prescription medications, as they could also have an impact on one's ability to drive.\nThere are a multitude of prescription medications that can alter a person's ability to safely operate a motor vehicle. Companies that manufacture these medications are required to provide a list of all possible side effects, as are the medical professionals who prescribe them to patients. However, this may not always happen, or an individual could choose to ignore them, perhaps believing the chances of experiencing these effects are too low to pay heed to them.\nOne might fully understand the risks of driving while on a sedative or narcotic. Unfortunately, even a medication for a condition such as blood pressure can create impairment, and if a traffic stop occurs under such circumstances, the driver could soon be facing accusations of driving under the influence. The penalties for similar charges are severe, and a conviction could have a devastating impact on a person's future.\nIndividuals who are facing DUI charges may wish to protect themselves from suffering unnecessary consequences, but the process can be complex. By speaking with a defense attorney, a person in Wisconsin could obtain some much-needed guidance on how best to approach the situation. An attorney can thoroughly evaluate the circumstances a client is facing and assist in pursuing the most favorable outcome possible during subsequent legal proceedings.\nSource: usnews.com, \"Does Your Medication Make You a Worse Driver?\", Mary Elizabeth Dallas, Accessed on Nov. 19, 2017", "pred_label": "__label__POS", "pred_score_pos": 0.8741668462753296}
{"content": "Authors Abstract\nThis work examined some physicochemical parameters of effluents from a Brewery Industry in Imo state. This company discharged effluents in non-compliance with the Nigerian National Regulations as confirmed from the Biochemical Oxygen Demand (BOD), Chemical Oxygen Demand (COD), Electrical Conductivity (EC), Nitrogen, and Turbidity results. The heavy metals have concentrations that were within WHO/FEPA limits. These confirmed results posed health risks to several rural communities which rely on the receiving water bodies as their primary source of domestic water. There is need for the intervention of appropriate regulatory agencies to ensure production of high quality treated final effluents. This scenario is typical of most industries in developing nations where enforcement of environmental regulations are deficient. To avoid pollution, regulatory authorities should closely monitor compliance by industries.\nGraphical Abstract Keywords Main Subjects", "pred_label": "__label__POS", "pred_score_pos": 0.7412676811218262}
{"content": "UCLA Core 1- and 3-derived O-glycans collectively maintain the colonic mucus barrier and protect against spontaneous colitis in mice. Author(s): Bergstrom, K Fu, J Johansson, MEV Liu, X Gao, N Wu, Q Song, J McDaniel, JM McGee, S Chen, W Braun, J Hansson, GC Xia, L et al. Published Web Locationhttps://doi.org/10.1038/mi.2016.45 Abstract\nCore 1- and 3-derived mucin-type O-glycans are primary components of the mucus layer in the colon. Reduced mucus thickness and impaired O-glycosylation are observed in human ulcerative colitis. However, how both types of O-glycans maintain mucus barrier function in the colon is unclear. We found that C1galt1 expression, which synthesizes core 1 O-glycans, was detected throughout the colon, whereas C3GnT, which controls core 3 O-glycan formation, was most highly expressed in the proximal colon. Consistent with this, mice lacking intestinal core 1-derived O-glycans (IEC C1galt1-/-) developed spontaneous colitis primarily in the distal colon, whereas mice lacking both intestinal core 1- and 3-derived O-glycans (DKO) developed spontaneous colitis in both the distal and proximal colon. DKO mice showed an early onset and more severe colitis than IEC C1galt1-/- mice. Antibiotic treatment restored the mucus layer and attenuated colitis in DKO mice. Mucins from DKO mice were more susceptible to proteolysis than wild-type mucins. This study indicates that core 1- and 3-derived O-glycans collectively contribute to the mucus barrier by protecting it from bacterial protease degradation and suggests new therapeutic targets to promote mucus barrier function in colitis patients.", "pred_label": "__label__POS", "pred_score_pos": 0.593553900718689}
{"content": "Learning Objectives Define and differentiate between power and authority Identify and describe the three types of authority Define common forms of government, such as monarchy, oligarchy, dictatorship, and democracy Compare common forms of government and identify real-life examples of each Explain the significance of “one person, one vote” in determining American policy Discuss how voter participation affects politics in the United States Explore the influence of race, gender, and class issues on the voting process Understand how functionalists, conflict theorists, and interactionists view government and politics\nDubbed the “wedding of the century” by journalists, dignitaries, and commoners alike, the April 29, 2011, nuptials of Prince William and Catherine Middleton ignited a media frenzy months before the ceremony even took place. Thousands of journalists reported on the ceremony, and the\nNew York Times estimated that 3 billion viewers watched the bride and groom exchange vows (Lyall 2011). In the weeks leading up to the event, speculation about the wedding was a frequent topic of conversation on televised news shows as well as in everyday conversation. When the morning of the wedding finally arrived, nearly a million British citizens lined its procession route to catch a glimpse of the royals making their way to the palace.\nThe popularity of Will and Kate, the Duke and Duchess of Cambridge, did not diminish when the ceremony concluded. Competing tabloids began to feature headlines that proclaimed divorce, pregnancy, and other sensational events in the couple’s life, while others focused on the particulars of Kate’s hairstyles, dresses, and hats. Still other media focused their attention on the philanthropic endeavors of the duke and duchess, who frequently use their influence to promote charitable endeavors.\nDespite their appeal and link to a long-standing monarchy, William and Kate, along with the other British royals, do not enjoy the same power their predecessors commanded in history. Instead, their role is largely symbolic. While Henry VIII, for instance, had the authority to order executions and make important state decisions based on what some might consider personal whims, today’s monarchs are more akin to celebrities who possess the wealth and fame to support their favorite causes.", "pred_label": "__label__POS", "pred_score_pos": 0.9462310671806335}
{"content": "Post Traumatic Stress Disorder, PTSD, is often noted in patients who have experienced a traumatic event during which they perceived themselves as helpless and unable to escape the circumstances.\nPTSD has been noted as one of the most life debilitating conditions that can lead to secondary mental illnesses such as Major Depressive Disorder, Hallucinations and Delusions, sexual disorders, and of course several types of addictions such as alcohol, drugs and even pornography.\nFamilies of afflicted persons with PTSD often suffer along with the afflicted person. Relationship dissatisfactions, domestic abuse, child abuse, elderly abuse, and even suicide are commonly experienced in the lives of untreated or poorly treated persons with PTSD.", "pred_label": "__label__POS", "pred_score_pos": 0.9403641223907471}
{"content": "Are you dealing with a spouse who is telling lies to your children? If you are, you are not alone. Unfortunately, some divorcing spouses engage in dirty, underhanded tactics. A husband, for example, may lie in court, claiming that his wife is a drug addict and incapable of looking after their children. A wife, in turn, may falsely claim that her husband abused her during the marriage and he continues to stalk her.\nIn both cases, the spouses resorted to false claims as a means of hurting each other and advancing their own agendas. Whether a court ultimately believes either spouse is open to debate.\nPerhaps even worse, some spouses spread lies to their children. Children are highly impressionable and may lack the ability to separate truth from fiction. This means that when one parent lies to the child about the other parent, the child is likely to believe the lies. Parents may succeed in poisoning a child’s mind against the other parent, resulting in a condition sometimes referred to as “parental alienation.” Under such circumstances, one parent attempts to alienate the child from the other parent through lies or other forms of manipulation. The parent who is the victim of these lies and manipulation (along with the child) faces a difficult and highly uncertain position. After all, how does one provide tangible proof in court that the other parent manipulated the child?\nWhile parental alienation is difficult to prove, those facing it should not lose heart. It is possible to successfully combat alienation by remaining calm, refraining from retaliation, and carefully documenting evidence wherever possible. Over time, a case can be built and the truth about a parent will eventually become clear in the eyes of both the court and the child.", "pred_label": "__label__POS", "pred_score_pos": 0.746943473815918}
{"content": "Invitations from the land and waters: Lessons from the Peace of Fort Garry Abstract\nThis paper offers critical perspectives on engaging Indigenous Peoples land-based practices in the city. Using Winnipeg as its case study, this research identifies Winnipeg and the Red River area as a major pre-settler Indigenous population centre. Through an examination of the making of a peace treaty between the Great Sioux Nation, the Métis, and the Saulteaux at Fort Garry as a moment for exploring the land and waters as sentient entities inviting Indigenous Peoples to gather and engage in political activities. This work provides insights into the way the land and waters convey invitations to other beings, and explores what political values and activities those invitations have the power to encourage. What follows contributes to the ongoing scholarship of reclaiming urban geographies as Indigenous spaces, and challenging the reserve-rural-remote world as an Indigenous space, and the urban as a non-Indigenous space. By thinking about Indigenous politics in the city through the framework of what the land and waters invite, readers will be opened to the potential to transform contemporary inter-Indigenous political and cultural activity in places like Winnipeg.\nCopyright: Institute of Urban Studies", "pred_label": "__label__POS", "pred_score_pos": 0.999264121055603}
{"content": "Resulting in an acute shortage of affordable rental units across the country. The crisis is particularly severe in Toronto Centre, where 66 percent of residents are renters – double the national average – and rents have skyrocketed. There are currently 87,000 households on the waiting list for subsidized housing in downtown Toronto.\nYet despite the shameful conditions faced by so many people, the federal government is cutting its limited support for social housing. Over the next five years, $500 million is set to be cut from current programs – including the elimination of long-standing funding for co-operative housing, which has served as a successful model for affordable housing. These cuts will exacerbate already unacceptable levels of poverty and homelessness in the riding. .\nWhile the federal government provides generous housing support for affluent Canadians (through the tax exemption for capital gains on principal residences), it is unwilling to provide even basic housing support for many of Canada’s most vulnerable citizens.\nCanada is now virtually the only country in the developed world without a national housing plan. We used to have one, but it was cut back by the Conservatives in the 1980s and then eliminated by the Liberals in the 1990s. Since then, there have been temporary injections of federal money, but funding has never been restored to pre-1990s levels.\nThe NDP has been alone in consistently pushing for a national housing strategy, with commitments for stable, long-term federal funding..", "pred_label": "__label__POS", "pred_score_pos": 0.7182145118713379}
{"content": "Single-family rent prices were on an upward path early this year, driven primarily by continued growth at the lower end of the market. In fact, rents rose 3.3% over the year in February, charting their biggest annual jump since August 2016, according to CoreLogic’s Single-Family Rent Index released Tuesday.\nOverall, single-family rents have been on the rise over the past decade, but they have decelerated somewhat since reaching a peak of 4.2% in February 2016, according to the index.\nWhile rents have grown overall across the market, rent price growth at the lower end of the market has been rising at a higher rate than the higher end of the market since April 2014. However, CoreLogic noted that the gap is closing.\nCoreLogic defines lower-priced rentals as those with prices lower than 75% of the median rent in their region. High-priced rentals are those that have rental prices more than 125% of the median rent in their region.\nAt the lower end of the market, rents charted a 3.6% year-over-year increase in February, down from a 4% annual gain recorded in February 2019.\nHowever, this rate is still higher than the 3% increase recorded at the high end of the market. Also, illustrating that narrowing gap between rent growth at the high and low ends of the market, CoreLogic mentioned, high-end rent growth is up from a 2.6% growth rate recorded in February 2019.\nCoreLogic attributed persistent rent growth to rental home inventory lagging demand.\nAmong the 20 large metro areas observed, Phoenix had the highest rate of annual rent growth in February at 6.2%. The metro was followed closely by the Seattle metro, where rents grew 6.1% over the year in February.\nPhoenix’s rent growth can be attributed in part to its strong economy and growing employment. In fact, employment grew 3.2% in Phoenix in February compared to 1.6% across the nation overall, according to CoreLogic.\nOther factors that can cause accelerated rent growth in a market are low vacancies among rental properties and limited construction.\nDetroit was the only metro to post a decline in rents in February with a 2.2% annual.\nHonolulu, Miami, and Philadelphia all posted rent growth under 2% in February.\nFebruary’s overall rent growth took place alongside strong employment growth for the month, but the departure that took place in March will likely make waves in the rental market.\nThe spike in unemployment sparked by the COVID-19 pandemic “has disrupted the typical rental demand and supply dynamic, which will ultimately impact rent growth in coming months,” according to CoreLogic.\nWhile noting that demand could detract in the short-term, Molly Boesel, principal economist at CoreLogic said Tuesday, “However, as we look ahead to an economic recovery, consumers may begin considering single-family rentals over multifamily options to provide more space for at-home offices and distance from other housing units.”", "pred_label": "__label__POS", "pred_score_pos": 0.5413293838500977}
{"content": "Acoustic beamforming has played a key role in the robust automatic speech recognition (ASR) applications. Accurate estimates of the speech and noise spatial covariance matrices (SCM) are crucial for successfully applying the minimum variance distortionless response (MVDR) beamforming. Reliable estimation of time-frequency (TF) masks can improve the estimation of the SCMs and significantly improve the performance of the MVDR beamforming in ASR tasks. In this paper, we focus on the TF mask estimation using recurrent neural networks (RNN). Specifically, our methods include training the RNN to estimate the speech and noise masks independently, training the RNN to minimize the ASR cost function directly, and performing multiple passes to iteratively improve the mask estimation. The proposed methods are evaluated individually and overally on the CHiME-4 challenge. The results show that the proposed methods improve the ASR performance individually and also work complementarily. The overall performance achieves a word error rate of 8.9% with 6-microphone configuration, which is much better than 12.0% achieved with the state-of-the-art MVDR implementation.", "pred_label": "__label__POS", "pred_score_pos": 0.8046208620071411}
{"content": "Feeling Cold When you burn calories, your body produces heat. This is the reason why you feel so hot after an intensive workout or exercise. However, due to the low level of thyroid hormones, the body does not burn enough calories resulting in less production of heat. As a direct result, you feel cold most of the time.", "pred_label": "__label__POS", "pred_score_pos": 0.9912000298500061}
{"content": "On Tuesday, Aphria (NYSE:APHA) reported its earnings for the second quarter of fiscal 2020. The company beat analysts’ EBITDA estimates. The second quarter was Aphria’s third consecutive quarter with positive EBITDA. However, the company missed analysts’ revenue estimates. Aphria’s management lowered its fiscal 2020 guidance due to the delay in the opening new stores, a temporary ban on vape products in Alberta, lower revenue growth in Germany, and increased expenses from third-party supplies. The increased expenses were due to a delay in licensing the Aphria Diamond facility. To learn more, read Aphria Cuts 2020 Guidance, Stock Falls.\nAphria stock fell due to weak sales and its lower fiscal 2020 guidance. On Tuesday, the stock fell to a low of 6.37 Canadian dollars before closing at 6.49 Canadian dollars—a fall of 8.6% from its previous closing price. Let’s look at analysts’ recommendations after Aphria’s second-quarter earnings.\nAnalysts’ recommendations for Aphria\nDespite Aphria lowering its fiscal 2020 guidance, CIBC upgraded the stock from “underperformer” to “neutral.” Overall, analysts are still bullish on the stock. Among the 14 analysts that follow the stock, ten recommend a “buy,” while four recommend a “hold.” None of the analysts recommend a “sell.” Aphria received increased coverage in the last 12 months. In January 2019, only nine analysts covered the stock.\nLet’s look at analysts’ recommendations for Aphria’s peers.\nAnalysts favor a “hold” rating for Canopy Growth (NYSE:CGC) (TSE:WEED). Among the 23 analysts, 13 recommend a “hold.” However, Jim Cramer is bullish on the stock. Read Why Does Jim Cramer Prefer CGC versus CRON? to learn more. Among the 15 analysts that follow HEXO (TSE:HEXO), only three analysts recommend a “buy.” Read, Has HEXO Stock Bottomed Out? for analysts’ estimates and ratings. For Cronos Group (NASDAQ:CRON), seven of 13 analysts recommend a “hold.” Analysts’ target prices\nFollowing Aphria’s second-quarter earnings, CIBC raised its target price, while Haywood Securities cut its target price. CIBC increased its target price from 6.50 Canadian dollars to 7 Canadian dollars. Haywood Securities lowered its target price from 11.75 Canadian dollars to 10.25 Candian dollars. As of Tuesday, analysts have a consensus target price of 11.96 Canadian dollars, which implies a 12-month return potential of 84.3%.\nSince April 2019, analysts’ consensus target price has been falling. Since then, the consensus target price has fallen by 28.7%. Weakness in the cannabis sector might have prompted analysts’ to cut their target prices. Aphria reported a strong performance in the fourth quarter of fiscal 2019 and the first quarter of fiscal 2020.\nAs of Tuesday, HEXO and Cronos Group were trading at a discount of 25.9% and 16.9% from their respective target price. However, Canopy Growth was trading 7.6% higher than analysts’ consensus target price.\nAnalysts’ opinions\nJefferies has a “buy” rating and a target price of 11 Canadian dollars. Notably, Jefferies was bullish after Aphria’s second-quarter earnings. As reported by MarketWatch, Owen Bennett of Jefferies said, “On sales trends, recreational sales were up 46% QoQ with volumes up 68%, while they also saw a need to buy wholesale in the quarter due to demand outstripping supply.” He also said, “This bodes well for further supply due to come online from the Diamond facility, and should give confidence that Aphria’s products will continue to take share.”\nAs reported by MarketWatch, CIBC analysts John Zamparo and Krishna Ruthnum are also bullish on the stock. They wrote in their research note that despite Aphria’s ongoing high capital expenditure and working capital investments, its balance sheet looks strong. They were encouraged by Aphria’s market share gains.", "pred_label": "__label__POS", "pred_score_pos": 0.6592923998832703}
{"content": "Abstract\nNarcolepsy is a chronic neurological disorder with significant impact on health-related quality of life. The disorder is often misunderstood, and considerably under-diagnosed. Research over the last ten years has made significant progress in identifying the causes and devising management solutions for this condition. Narcolepsy’s complexity can make the disorder challenging for the individual to manage, requiring neuroscience nurses to be knowledgeable about the condition and its optimal management. This article is the first part of two, focusing on narcolepsy, offering a definition of the disorder, the pathophysiological process of the condition, and how this is manifested in the individual. The second part will focus on diagnosis and management of the condition\nOriginal language English Pages (from-to) 108-114 Journal British Journal of Neuroscience Nursing Volume 4 Issue number 3 Publication status Published - Mar 2008", "pred_label": "__label__POS", "pred_score_pos": 0.8553579449653625}
{"content": "When I found out about COVID-19, I was on a beach in Rome. I hadn’t joined the nursing profession yet because I was missing credit in french literature to graduate. I decided to travel to Rome to get away considering my class was online anyway. I remember receiving a call from my mom in a panic, asking me to come home immediately because they were closing the borders and I would be stuck in Italy. A few days later I was on a plane to Montreal. Upon landing, I could see the fear in people’s eyes. In a short time frame, the world we once knew was completely changed. I was exempted from writing my EUF exam so I could get my diploma to start working immediately. I started my first CEPI job in geriatrics. I was working in a residence with semi-autonomous patients. We had very little information about COVID, which created a lot of anxiety. On a daily basis, I would worry about potentially contaminating my patients and my family. The fear of harming my loved ones was too great. I decided to live in a hotel close to the residence for the time being. My life revolved around COVID-19. Despite how overworked and tired I was, I also felt fulfilled. That is until I had my first COVID scare. Three of my patients tested positive and I couldn’t help but blame myself. The sense of guilt was so strong I contemplated quitting my job, but I couldn’t. I couldn’t leave my patients alone because I had a sense of responsibility towards them. I decided to change my attitude regarding the situation we were living in. From that moment, I knew things were going to be ok. I would wake up with a positive outlook on life and that would carry me through my day. This pandemic has taught me that I have grit. I chose to make nursing my profession for better or for worse, and regardless of the challenges I may face in my career, I’ll find a way to push through and persevere.", "pred_label": "__label__POS", "pred_score_pos": 0.8305238485336304}
{"content": "Coronavirus Provides Glimpse Into Clean Air\nMarch 31, 2020—Nitrogen dioxide has reduced following the COVID-19 virus outbreak, which provides a glimpse into what the U.S.'s air quality could like if electric cars were the norm, reported\nElectrek.\nEarther has produced a map of nitrogen dioxide captured from satellite images. Nitrogen dioxide is produced by fossil fuel burning. The map shows a reduction from just two months ago.\nAccording to the report, the data gathered during the crisis is expected to be used to better understand how human activity produces emissions in different regions.", "pred_label": "__label__POS", "pred_score_pos": 0.5638322830200195}
{"content": "ABSTRACT\nDirected secretion of cytotoxic granules into target cells constitutes a central function of natural killer (NK) cells, which requires extensive remodeling of actin and microtubule cytoskeleton at the site of NK/target cell interaction (immune synapse, IS). To date, the mechanisms coordinating cytoskeleton remodeling are not entirely understood. A-kinase anchoring protein 350 (AKAP350) is a centrosome/Golgi associated protein with a prominent role in microtubule nucleation. Our studies revealed that reduction of AKAP350 expression by stable expression of specific shRNAs inhibited actin and lymphocyte function-associated antigen-1 (LFA-1) reorganization at the IS and centrosome translocation to this site, therefore decreasing NK cytolytic activity. In NK cells, the CDC42 interacting protein 4 (CIP4) participates in centrosome translocation to the IS, where it has been proposed to integrate microtubule and actin interaction. Our studies showed that AKAP350 recruited CIP4 to the centrosome and conditioned its localization at the IS. Besides, we found that, during NK activation, AKAP350 was essential for nucleation of microtubules at the Golgi apparatus. Disruption of the Golgi function by BFA treatment or by AKAP350 delocalization from the organelle impaired LFA-1 clustering at the IS. Similarly, microtubule depolymerization and microtubule stabilization inhibited LFA-1 reorganization at the IS, without affecting actin remodeling. Altogether, our studies indicate that AKAP350 regulates distinct events at the Golgi apparatus and at the centrosome that are crucial for microtubule and actin remodelling and have a great impact on IS maturation during NK cytotoxic immune response.\nCompeting Interest Statement\nThe authors have declared no competing interest.", "pred_label": "__label__POS", "pred_score_pos": 0.6881054639816284}
{"content": "Charu Gupta, Dhan Prakash and Sneh Gupta\nAccepted Abstracts: J Cancer Sci Ther\nCancer cells have unique properties that can be exploited by nano-particles. Their rapid rate of growth causes them to intake an abnormal amount of nutrients (i.e., folic acid). Nano-particles (NP) can be used to target bio-markers or antigens that are highly specific to cancer cells. The nano-particles are typically between 20-150 nm or roughly 100 times smaller than most human cells. In the nanotechnology methods, certain NP can be designed to absorb preferentially certain wave length of radiation and if they enter in the cancerous cells, they will burn them. Nanotechnology can be used to create therapeutic agents that target specific cells and deliver toxin to kill them. The NP will circulate through the body, detect cancer associated molecular changes, assist with imaging, release a therapeutic agent and then monitor the effectiveness of the intervention. Diamond nano-particles are now finding new and far-reaching applications in modern biomedical science and biotechnologies. Due to its excellent biocompatibility, nano-diamonds serve as versatile platforms that can be embedded within polymer-based microfilm devices. The nano-diamonds are complexed with a chemotherapeutic, and subsequently enable sustained/slow release of the drug for a minimum of one month, with a significant amount of drug in reserve. This opens up the potential for highly localized drug release as a complementary and potent form of treatment with systemic injection towards the reduction of continuous dosing, and as such, attenuation of the often powerful side effects of chemotherapy. Nano-diamonds are quite economical, enabling the broad impact of these devices towards a spectrum of physiological disorders e.g. serving as a local chemotherapeutic patch, or as a pericardial device to suppress inflammation after open heart surgery. A substantial amount of drug can be loaded onto clusters of nano-diamonds, which have a high surface area. The nano- diamonds are then put between extremely thin films of parylene, resulting in a device that is minimally invasive. Nano-diamond patch could be used to treat a localized region where residual cancer cells might remain after a tumor is removed. If a tumor has to be removed from the breast or brain, the device could be implanted in the affected area as part of the same surgery. This approach, which confines drug release to a specific location, could mitigate side effects and complications from other chemotherapy treatments. Thus, the nano-diamonds can be used to explore a broad range of therapeutic classes, including additional small molecules, proteins, therapeutic antibodies, RNAi, etc.\ntempobet\ntempobet giriş\ntempobet giriş\nsüperbetin\nmobilbahis giriş", "pred_label": "__label__POS", "pred_score_pos": 0.7069883346557617}
{"content": "On September 11, 2001 terrorists hijacked commercial airliners and flew them into the World Trade Center towers and the Pentagon. The attacks remain the deadliest and most expensive terrorist incidents in U.S. history, with insurance losses totaling about $47.0 billion in 2019 dollars, according to I.I.I. estimates.\nIn the wake of the attacks the U.S. Congress enacted the Terrorism Risk Insurance Act of 2002 (TRIA). The act creating a federal backstop for catastrophic terrorism losses that is designed to keep terrorism risk insurance available and affordable. It was renewed in 2005, 2007 and again in 2015. The act is set to expire on December 31, 2020.\nOver the next months the Triple-I Blog will run stories featuring key participants in the terrorism risk insurance market and highlight news stories from our database from the periods immediately following 9/11 (before TRIA) and 2015 (when TRIA briefly lapsed).\nBelow is an abstract from the I.I.I. database citing a\nBestWeek article from October 1, 2001. The article refers to the fact that the heaviest insured losses were absorbed by foreign and domestic reinsurers, the insurers of insurance companies. Because of the lack of public data on, or modeling of, the scope and nature of the terrorism risk, reinsurers felt unable to accurately price for such risks and largely withdrew from the market for terrorism risk insurance in the months following September 11, 2001\nFor more on the importance of a federal terrorism backstop read the I.I.I. report,\nA World Without TRIA: Incalculable Risk .", "pred_label": "__label__POS", "pred_score_pos": 0.6190639734268188}
{"content": "The Coronavirus Aid, Relief, and Economic Security Act (the “CARES Act”) and related federal programs provided vital funding to organizations across the U.S. – including not-for-profit, governmental, and for-profit entities. If total federal award expenditures related to certain programs exceeded $750,000 for an individual fiscal year, your entity will be required to have a single audit in accordance with 45 CFR 75.\nWhile specific guidance regarding compliance testing of COVID-19 related funding is expected to be provided in an addendum to the Office of Management and Budget (OMB) 2020 Compliance Supplement this fall, there are steps an entity can be taking now to prepare for its single audit.", "pred_label": "__label__POS", "pred_score_pos": 0.9986667037010193}
{"content": "Abstract\nInfections remain a common complication of solid organ transplantation. Early postoperative infections remain a significant cause of morbidity and mortality in solid organ transplant (SOT) recipients. Although significant effort has been made to understand the epidemiology and risk factors for early nosocomial infections in other surgical populations, data in SOT recipients are limited. A literature review was performed to summarize the current understanding of pneumonia, urinary tract infection, surgical-site infection, bloodstream infection, and Clostridium difficult colitis, occurring within the first 30 days after transplantation.\nKeywords Bacteremia C. difficile colitis Nosocomial infections Pneumonia Surgical site infection Urinary tract infection ASJC Scopus subject areas Infectious Diseases Transplantation", "pred_label": "__label__POS", "pred_score_pos": 0.9012112617492676}
{"content": "Bridges\nA bridge may be recommended if you're missing one or more teeth. Gaps left by missing teeth eventually cause the remaining teeth to rotate or move into the empty spaces, resulting in a bad bite. Imbalances caused by missing teeth can also lead to gum disease and temporomandibular joint (TMJ) disorders.\nBridges are commonly used to replace one or more missing teeth. They fill the space where the teeth are missing. Bridges are cemented or bonded (depending on type of bridge) to the natural teeth or implants surrounding the empty space. These teeth serve as anchors for the bridge. A replacement tooth, is attached to the crowns that cover the natural teeth. As with crowns, you have a choice of materials for bridges. Depending on your individual situation we will discuss the choices available, based on the location of the missing tooth (or teeth), its function, aesthetic considerations and cost. Porcelain or ceramic bridges can be matched to the color of your natural teeth and appear as real as natural teeth.", "pred_label": "__label__POS", "pred_score_pos": 0.9303430914878845}
{"content": "Abstract\nThe tumor suppressor bridging integrator 1 (BIN1) is a corepressor of the transcription factor E2F1 and inhibits cell-cycle progression. BIN1 also curbs cellular poly(ADP-ribosyl)ation (PARylation) and increases sensitivity of cancer cells to DNAdamaging therapeutic agents such as cisplatin. However, how BIN1 deficiency, a hallmark of advanced cancer cells, increases cisplatin resistance remains elusive. Here, we report that BIN1 inactivates ataxia telangiectasia mutated (ATM) serine/threonine kinase, particularly when BIN1 binds E2F1. BIN1 12A (a cancer-associated BIN1 splicing variant) also inhibited cellular PARylation, but only BIN1 increased cisplatin sensitivity. BIN1 prevented E2F1 from transcriptionally activating the human ATM promoter, whereas BIN1 12A did not physically interact with E2F1. Conversely, BIN1 loss significantly increased E2F1-dependent formation of MRE11A/RAD50/NBS1 DNA end-binding protein complex and efficiently promoted ATM autophosphorylation. Even in the absence of dsDNA breaks (DSBs), BIN1 loss promoted ATM-dependent phosphorylation of histone H2A family member X (forming γH2AX, a DSB biomarker) and mediator of DNA damage checkpoint 1 (MDC1, a γH2AX-binding adaptor protein for DSB repair). Of note, even in the presence of transcriptionally active (i.e. proapoptotic) TP53 tumor suppressor, BIN1 loss generally increased cisplatin resistance, which was conversely alleviated by ATM inactivation or E2F1 reduction. However, E2F2 or E2F3 depletion did not recapitulate the cisplatin sensitivity elicited by E2F1 elimination. Our study unveils an E2F1-specific signaling circuit that constitutively activates ATM and provokes cisplatin resistance in BIN1-deficient cancer cells and further reveals that γH2AX emergence may not always reflect DSBs if BIN1 is absent.\nASJC Scopus subject areas Biochemistry Molecular Biology Cell Biology", "pred_label": "__label__POS", "pred_score_pos": 0.8709239363670349}
{"content": "Abstract\nPURPOSE. Understanding the role of mitochondria in retinal ganglion cells (RGCs) is relevant to human disease as studies have shown mitochondrial abnormalities in primary open-angle glaucoma patients. This study seeks to determine the effects of the sigma-1 receptor (σ-1r) and its agonists on mitochondrial function in oxygen-and glucose-deprived (OGD) purified neonatal RGCs. METHODS. Retinal ganglion cells were isolated from rat pups and subjected to OGD in varying conditions in the presence or absence of σ-1r agonist and antagonist and following addition of an AAV2-σ-1r vector that was used to increase σ-1r expression. Western blots and immunofluorescence microscopy validated findings. Mitochondrial function was determined by measuring mitochondrial membrane potential (Δψ\nm) using the dye, fluorescence tetraethylbenzimidazolylcarbocyanineiodide (JC-1), and determination of cytochrome c oxidase activity using a cytochrome c oxidase assay kit. Caspase 3 and 7 activities were also measured using a luminescent assay kit. RESULTS. Oxygen and glucose deprivation in RGCs resulted in decreased mitochondrial membrane potential and cytochrome c oxidase activity when compared with normoxic RGCs. σ-1r agonists or overexpression of the σ-1r restored the mitochondrial membrane potential comparable to normoxic conditions, while σ-1r antagonists abolished these effects. Oxygen and glucose depreavtation induced decreases in cytochrome c activity were partially restored by overexpression or activation of σ-1r. Caspase activity was increased in response to OGD and was decreased by the addition of σ-1r agonist, pentazocine, and following σ-1r overexpression. CONCLUSIONS. These data suggest that activation and/or overexpression of σ-1r restores RGCs mitochondrial function following OGD and that mitochondrial function is vital to the function of RGCs. Keywords Mitochondria Oxygen and glucose deprived Retinal ganglion cells Sigma-1 receptor", "pred_label": "__label__POS", "pred_score_pos": 0.5615733861923218}
{"content": "The Key Differences Between Shrimp and Crawfish\nLive crawfish and shrimp have several similarities, that cause many people to mistake one crustacean for another. These two types of decapods have a similar appearance, identified by their chitin exoskeleton, multiple legs, antennae and crawling movement across sandy or muddy sea floors. There are, however, a few key differences that can make all the difference, especially if you are ordering live crawfish or shrimp to be shipped without assessing these crustaceans in person.\nMain Differences Between Shrimp and Crawfish Origin\nOne of the key differences between shrimp and crawfish is their place of origin. While crawfish is primarily found in freshwater locations, shrimp is normally found in saltwater. Live crawfish can be found in many different forms including red crawfish, green signal crawfish and many others depending on the specific harvest location, which the live crawfish is shipped from.\nFunction\nShrimp have a reputation for being the cleaner of the two crustaceans as this species is responsible for cleaning fungi and other harmful bacteria from fish in saltwater regions. Crawfish do not serve this cleaning function, and are rather, active at night as this is a nocturnal species, which is frequently found in swamp areas.\nAppearance\nThe most notable difference in the appearance of these two decapods is their size. While the average shrimp is no longer than 4 inches, the average crawfish is more substantial at a typical length of 8 inches. Crawfish also tend to be darker in color, often presenting a deep orange or brown hue, while shrimp are normally a soft orange color. Shrimps have long, tail-like abdomens, which allow for fast swimming, while the crawfish can be identified by its signature large claws, which shrimp do not have.\nTaste\nLive shrimp and crawfish can be shipped overnight from online fresh seafood marketplaces like Farm-2-Market for the most convenient way to purchase fresh seafood. Shoppers should, therefore, be aware of the differences in taste between these two crustaceans before ordering seafood online, to get the right products for the recipes, which this seafood is intended for. Crawfish can be described as a softer alternative to hard-shelled shrimp, boasting a crab-like taste with subtle notes of shrimp flavor.", "pred_label": "__label__POS", "pred_score_pos": 0.7323262691497803}
{"content": "We supply commercial quantities of functionalised graphene ink which is used to print test strips in the self-diagnostic biomedical sensor device market for diabetes monitoring.\nOur graphene ink is the first of its kind being used in volume in this market, having gained regulatory approvals, including extensive production quantity in-line testing.It is proving to be a high quality, more stable, and consistent product, replacing the established graphite and carbon inks used extensively in producing the test strips for this significant global market.\nIn addition, as a second phase some customers are now trialling an all-carbon sensor utilising our graphene-enhanced ink that is aimed at removing the need for the expensive silver conductive ink tracks extensively used today. The outcome is a more environmentally friendly (potentially recyclable) product, and if achieved, we believe that this breakthrough could have a significant effect on the industry.\nWe are gaining significant market attention due to the quality, stability, adhesive properties and consistency of our graphene inks compared to the widely used graphite and other carbon materials available today. A crucial metric used by the specialist printers to measure the repeatability and accuracy of sensor readings delivered by the inks they use is its coefficient of variation or C/V ratio, where a low percentage indicates a high consistent, repeatability factor. Reports received by HTW from printers using its graphene inks have shown an exceptionally low C/V ratio of approximately 0.5%, demonstrating an accuracy rating of over 99%, which is believed to be well above the industry norm.", "pred_label": "__label__POS", "pred_score_pos": 0.9813575148582458}
{"content": "HMRC have updated their JRS guidance to reflect the anticipated changes.\nHMRC have updated their Job Retention Scheme (JRS) guidance to reflect anticipated changes. The changes appear to be as expected, with the introduction of wording that revises what employers should do when calculating a claim if an employee stops being furloughed, or flexibly furloughed, partway through a claim period.\nWe reported in our article ‘Job Retention Scheme – claim periods and flexible furlough’ (7 September 2020) that HMRC were expected to update their guidance on calculating JRS claims for the period in which an employee returns to full time work. The expected amendments have now been made.\nWhat’s changed? “Calculating the number of working and furloughed hours for an employee that comes off furlough or flexible furlough partway through a claim period. If your employee stops being furloughed or flexibly furloughed partway through a claim period, when calculating the number of furloughed hours you can claim for, make sure you: This applies even if your claim period includes days after the employee’s last day of furlough (for example, because you’re claiming for multiple employees and some of them stay on furlough). You do not need to amend any previous claims submitted prior to 14 September 2020 for these employees. You should use this calculation for any claims from 14 September 2020, for an employee who stops being furloughed or flexibly furloughed partway through a claim period.” KPMG comment\nAs initial observations, HMRC’s updated guidance does not specify what ‘come off’ furlough means, nor does it address whether having come off furlough, it is possible in HMRC’s view, to go back on. Similarly, it is not immediately clear whether any employees who might have been disadvantaged under the old approach, could compel their employer to amend historic claims.\nWe will engage with HMRC with a view to confirming these points, but it is likely that this will be dependent upon the legal documentation and communications which are given to employees.\nWhat does this mean for employers?\nIn principle, this is a welcome simplification. However, employers must confirm the specific implications for them based on the wording of their own flexible furlough agreements and any other correspondence with employees who return to work.\n© 2020 KPMG LLP a UK limited liability partnership and a member firm of the KPMG global organisation of independent member firms affiliated with KPMG International Limited, a private English company limited by guarantee. All rights reserved.\nFor more detail about the structure of the KPMG global organisation please visit https://home.kpmg/governance.", "pred_label": "__label__POS", "pred_score_pos": 0.7413303852081299}
{"content": "SEARCH FOR RESOURCES\nPosted resources are related to educational innovations, policies, and best practices within the health professions that support teaching and learning.\nCOLLECTIONS\nThis resource collection was built in response to the COVID-19 pandemic’s significant impact on the teaching and learning of health professionals. Designed by diverse educators, this working collection features clinical learning experiences, which can be readily used or easily adapted for specific, local settings, without the need for physical patient contact.\nStudents are eager to help in the response to the COVID-19 pandemic, and it is critical that those efforts be responsive to health system needs, prioritize student and community safety, and be undertaken jointly with students, schools, and health systems. This collection of resources includes student volunteer and service projects done in collaboration with health systems and medical schools that, when feasible, facilitate social distancing.", "pred_label": "__label__POS", "pred_score_pos": 0.8463813066482544}
{"content": "- Provides clinically effective high doses of vitamins D per capsule to achieve optimal serum levels\n- Optimal form of vitamin D: D3 has greater potency than D2 for increasing serum and storage levels of vitamin D\n- In a base of organic flaxseed oil for improved intestinal absorption\n- Easy to swallow and highly bioavailable softgel\nThe evidence for vitamin D’s importance continues to grow, documenting both widespread insufficiency as well as therapeutic efficacy. Vitamin D receptors are linked to chromosomes in nearly every cell and tissue, with diverse and organ-specific effects. Vitamin D has both hormonal and non-hormonal functions, with the ubiquity of vitamin D receptors translating into a myriad of physiological actions, ranging from bone metabolism to modulation of immune activity. It regulates the expression of hundreds of genes, influences cellular proliferation and signaling, insulin production and sensitivity, and is a critical inhibitor of several inflammatory pathways. Lower levels have now been associated with a higher incidence of both acute and chronic illness, including autoimmune disease, cardiovascular disease, cancer, diabetes, hypertension, infertility, and overall mortality rates. All-cause mortality is the lowest in those with 25-OH vitamin D levels between 75 to 112.5 nmol/L, in many cases requiring high doses to achieve, also true for those with genetic variants. A dose of nearly 10,000 IU was needed to achieve levels in this optimal range for 98% of individuals in a community based study of nearly 4000.", "pred_label": "__label__POS", "pred_score_pos": 0.6481906175613403}
{"content": "Since the adoption of the DSM-5, there appears to be a shift of focus away from the expressive language difficulties of children with autism spectrum disorder (ASD) to their social communication difficulties only. A significant body of research, on the other hand, has revealed that many children with ASD present with language impairment similar to that found in children with specific language impairment (SLI). It appears that a comprehensive test such as the CASL has not been used to investigate the differences in language impairment in children with ASD and SLI.The aim of the present study was to compare the oral language abilities of children in middle childhood with ASD (n=11) and SLI (n=12) to the corresponding abilities of a matched control group of children with typical development (TD) (n=12). All participants were EAL learners and came from bilingual or multilingual backgrounds. The group with ASD were high functioning. Lexical semantic, syntactic, supralinguistic, and pragmatic abilities were investigated using the CASL. A standard-group comparison design was used and participants were purposively assigned to the three groups (ASD, SLI, and TD). Differences in language scores were determined using analysis of variance and Tukey’s test.Results showed no significant differences between the participants with ASD and SLI for lexical semantic, syntactic, and supralinguistic abilities, but significant differences were evident when their results were compared to those of the TD participants. Great variability was seen in the language abilities of participants with ASD and SLI with the majority scoring one or more standard deviations below the mean of the CASL. Mean scores for pragmatics for the three participant groups differed significantly, with ASD<SLI<TD. Some participants with ASD demonstrated patterns of oral language deficits similar to children with SLI, thereby confirming results of previous findings.The results suggest that pragmatic and supralinguistic abilities should be included in the language assessment of children with ASD and SLI. It appears that the CASL can be applied as a successful tool to identify specific language deficits in children with ASD, but may not fully describe oral language deficits such as echolalia in children with ASD. The results imply that the language impairments of children with ASD and SLI are on a continuum where differences can be seen in severity. This study contributes to a database for multilingual South African children with language impairment.\nDescription:\nDissertation (MComm Path)--University of Pretoria, 2015.", "pred_label": "__label__POS", "pred_score_pos": 0.8429271578788757}
{"content": "Abstract\nDespite the multiple causes of the shock state, all causes possess the common abnormality of oxygen supply not meeting tissue metabolic demands. Compensatory mechanisms may mask the severity of hypoxemia and hypoperfusion, since catecholamines and extracellular fluid shifts initially compensate for the physiologic derangements associated with patients in shock. Despite the achievement of normal physiologic parameters after resuscitation, significant metabolic acidosis may continue to be present in the tissues, as evidenced by increased lactate levels and metabolic acidosis. This review discusses the major endpoints of resuscitation in clinical use.\nKeywords Hypoperfusion Oxygen demand Resuscitation Shock ASJC Scopus subject areas Surgery", "pred_label": "__label__POS", "pred_score_pos": 0.9997764229774475}
{"content": "The 6th Asia-Pacific Climate Change Adaptation Forum is scheduled to convene in Manila, the Philippines, from 17-19 October 2018.\nThe “Environment, Conflict and Cooperation” (ECC) exhibition visualizes the dramatic and growing impact of global environmental change. It demonstrates how climate change can threaten the security of the Asian continent, and showcases how climate, environment and sustainable development cooperation can contribute to stability and peace. Dealing with themes such as water, natural resources and climate change, the exhibition shows how environmental degradation and resource scarcity can spark conflict and create new security risks.\nThe exhibition “Environment, Conflict, Cooperation” (ECC), co-organised by The University of Queensland and adelphi, supported by the German Federal Foreign Office, is shown in Brisbane during 18\nth July and 4 th August. The exhibition is accompanied by a public talk as well as a closing panel discussion:\nThe exhibition “Environment, Conflict and Cooperation” (ECC), supported by the German Federal Foreign Office, is shown at the Manipal University during 8-17 April 2016. The exhibition is accompanied by lectures and panel discussions.", "pred_label": "__label__POS", "pred_score_pos": 0.5577888488769531}
{"content": "It’s hard to find value stocks, especially given the stellar bull run following the pandemic-led selloff. However, a few TSX-listed stocks continue to trade cheap, as the massive demand erosion and uncertain economic outlook continue to limit the recovery process.\nWhile these stocks could take at least a couple of years to bounce back to the pre-pandemic levels, they continue to offer high dividend yields, which is pretty safe and sustainable.\nIf you are looking for high yields amid a lower interest rate environment, consider buying these dividend-paying stocks at a good bargain.\nPembina Pipeline\nWith its shares down about 37% year to date, North America’s leading energy infrastructure company\nPembina Pipeline (TSX:PPL)(NYSE:PBA) offers great value and a high dividend yield. While the lower oil prices remain a drag on Pembina Pipeline’s financial performance, it operates a low-risk business with diversified cash flow streams.\nPembina Pipeline pays its dividends through the fee-based cash flows from assets having no direct commodity exposure, suggesting that its dividends are safe, despite the uncertain energy outlook.\nThe company derives the majority of its adjusted EBITDA from the assets backed by fee-based, long-term contracts. Further, these contracts have agreements that reduce the volume and price risk.\nPembina Pipeline is paying a monthly dividend of $0.21 per share, reflecting an annual dividend yield of over $8.8%.\nBank of Nova Scotia Bank of Nova Scotia (TSX:BNS)(NYSE:BNS) is another top TSX stock offering a stellar dividend yield. Its stock is trading cheap, reflecting a year-to-date decline of over 19%. The higher provisions for credit losses and lower interest rates remained a drag on bank stocks. However, with the sequential improvement in the provisions, the pressure on the bank’s bottom line is likely to ease.\nThe bank’s dividends have grown by 6% annually over the last decade, thanks to its ability to generate solid earnings growth. Further, with the uptick in economic activities, Bank of Nova Scotia is likely to witness an acceleration in loans and deposit volumes, which should support the recovery in its stock and drive its dividends.\nBank of Nova Scotia currently pays a quarterly dividend of $0.90 per share, with an annual dividend yield of 6.5%.\nEnbridge\nSpeaking of stocks trading cheap and offering good dividends, consider buying the shares of energy infrastructure giant\nEnbridge (TSX:ENB)(NYSE:ENB). Like Pembina Pipeline, lower oil prices weighed on its stock. However, the company continues to pay robust dividends, thanks to its diversified cash flows.\nSo far, Enbridge stock is down about 23% this year and is trading at an attractive forward EV-to-EBITDA multiple of 11.4.\nEnbridge is known for returning a boatload of cash to its shareholders in the form of dividends. Over the past 12 years, its dividends have grown at a CAGR (compound annual growth rate) of 14%. Besides, it paid about $6 billion in dividends last year.\nEnbridge currently pays a quarterly dividend of $0.81 per share, reflecting an annual dividend yield of 8.5%.\nBottom line\nThese stocks are trading cheap for good reasons, and it could at least 24 months for these companies to reach the pre-pandemic level. However, the payouts of all these companies are pretty safe. A $10,000 investment in each of these stocks could fetch you an annual dividend income of about $2,385, which reflects a high annual yield of about 8%.\nSpeaking of value stocks...\nMotley Fool Canada's market-beating team has just released a brand-new FREE report revealing 5 \"dirt cheap\" stocks that you can buy today for under $49 a share. Our team thinks these 5 stocks are critically undervalued, but more importantly, could potentially make Canadian investors who act quickly a fortune. Don't miss out! Simply click the link below to grab your free copy and discover all 5 of these stocks now. Fool contributor Sneha Nahata has no position in any of the stocks mentioned. The Motley Fool owns shares of and recommends Enbridge. The Motley Fool recommends BANK OF NOVA SCOTIA and PEMBINA PIPELINE CORPORATION.", "pred_label": "__label__POS", "pred_score_pos": 0.7512263059616089}
{"content": "When you file for bankruptcy, the court imposes an automatic stay. This part of bankruptcy law protects consumers from collection attempts while they go through the bankruptcy process. It also applies to the vast majority of creditors. As soon as an individual files for bankruptcy, the automatic stay goes into effect. It prevents individual creditors and companies from continuing collection attempts against a debtor.\nHow It Protects You\nFor those in substantial financial trouble prior to bankruptcy, the automatic stay can be a huge relief. Creditors cannot start or continue court proceedings against a debtor once the stay is in place. Nor can they create or enforce a lien against their property, or repossess collateral. If a creditor violates any part of the automatic stay, you may be able sue them and seek damages.\nThe automatic stay assumes good faith on the part of the debtor. If a consumer is unable to pay their debt, it doesn’t make sense to have them continue to make payments during bankruptcy. The automatic stay assumes that the bankruptcy will be successful. It allows the debtor to begin using their money to cover other expenses.\nAdditionally, the automatic stay helps creditors. Without the automatic stay, creditors could find out that a debtor was filing bankruptcy and try to seize their assets before other creditors could make their claims. With the automatic stay, any assets that can be seized for debt payments are distributed fairly across all creditors.\nHow Long It Lasts\nThe stay begins as soon as you file bankruptcy. It continues until the bankruptcy is granted and the debts are discharged, or until the case is dismissed. In the event that your bankruptcy case is dismissed, you must resume making payments.\nExceptions\nCertain proceedings are not stopped by an automatic stay. If your landlord has already secured a judgment of possession, they can continue the eviction process. Domestic support, including child support, continues during the automatic stay. Criminal prosecutions are also not part of an automatic stay. For example, if you are convicted of fraud and are required to pay a fine, you must still pay the fine.\nAdditionally, creditors can request that the stay be lifted. These requests are typically only granted in situations where the debtor is behind on payments on a secured debt. Examples of secured debt, such as a car loan or mortgage.\nBankruptcy could be your opportunity to start over and change your financial future. Learn more about your options by contacting Lucid Law at 908-738-8245.", "pred_label": "__label__POS", "pred_score_pos": 0.9918273687362671}
{"content": "ParentS\n\"And you must commit yourselves wholeheartedly to these commands that I am giving you today. Repeat them again and again to your children. Talk about them when you are at home\" Deuteronomy 6:5-6\nA new study released by the Josh McDowell Ministry has unveiled current findings about teens and\nyoung adults, and pornography. According to the ministry's press release, the study is the \"most\ncomprehensive, in-depth and wide-ranging study to date on pornography among the American\npopulation.\"\nKey findings of the new study included:\n- Twice as many young adults ages 25-30 first viewed pornography before puberty than did the\nprevious generation (Gen X).\n- Teens aged 13-17 are watching more pornography and seeking it out more than any other\ngeneration, with 8% viewing porn daily, 18% weekly, and 17% once or twice a month.\n- 8% of teens say they come across porn daily even when they aren't seeking it out, 21% do so\nweekly, and 21% say they do so once or twice a week.\n- When teens talk about pornography with friends, 90% say they do so in an either neutral,\naccepting, or encouraging way.\n- Less than one-third (32%) of teens and young adults say that viewing pornography is \"usually or\nalways wrong\" compared to more than half (56%) who say not recycling is \"usually or always\nwrong.\"\n- Only one in 10 teens say their friends think viewing pornography is a bad thing.\n- Most teens and young adults have been involved in \"sexting,\" with 66% saying they have received\na sexually explicit image, and 41% have sent one.\nNow What?\n- Assume your teen will be exposed to pornography on a regular basis (whether intentionally or\nunintentionally.)\n- Understand the difference between a teen that stumbles upon online pornography and a teen that\nseeks it out. React appropriately based on behavior.\n- Make discussing pornography a topic of discussion with your teens.\n- Set clear expectations for online behavior regarding pornography.\n- If your teen is regularly viewing pornography consider using an accountability tool such as the ones\nfound on xxxchurch.com.", "pred_label": "__label__POS", "pred_score_pos": 0.5485058426856995}
{"content": "The 1000 days (143 weeks) of bulletin reflections ends December 10, 2017. The campaign began with our belief that the 1000 days from conception through a child's second birthday are the most crucial for a child's development. These 1000 days are our best opportunity to shape a healthier, more prosperous future for the child. All children.\nNineteen topics were covered in these 143 short bulletin reflections:\nAbortion Breast Feeding Domestic Education Environmental Pollution HIV/Aids Hunger Immigration International Malnutrition Maternal Mortality Mothers and Fathers Normality Nutrition Peace Poverty Stress Water Women’s Rights", "pred_label": "__label__POS", "pred_score_pos": 0.9931038618087769}
{"content": "EU-JAMRAI coordinator Professor Marie-Cécile Ploy presented during the seminar \"One Health antibiotic resistance\" the causes of antimicrobial resistance and the practices that are contributing to increase this problem in both animal and human health. Organized by the Veterinary Technical Groups of Nouvelle Aquitaine, this seminar gathered doctors and veterinarians highlighting the importance of the \"One Health\" approach to tackle this global health challenge.\nTo see the agenda please click here\nNecessary cookies are absolutely essential for the website to function properly. This category only includes cookies that ensures basic functionalities and security features of the website. These cookies do not store any personal information.\nAny cookies that may not be particularly necessary for the website to function and is used specifically to collect user personal data via analytics, ads, other embedded contents are termed as non-necessary cookies. It is mandatory to procure user consent prior to running these cookies on your website.", "pred_label": "__label__POS", "pred_score_pos": 0.9172534346580505}
{"content": "As usual during Europe’s lengthy summer vacation period, there has been a slowdown in tropical hardwood trading. Importers in many parts of Europe suggest that overall trade during the first half of 2011, while unspectacular, was an improvement on the same period the previous year. However, the volumes involved were well down on levels prevailing before the recession and there is little expectation of any significant upturn when buyers return at the end of August. On-going concerns about the debt crises in the euro-zone and government austerity measures has contributed to a general feeling of uncertainty about the future direction of demand and raised the spectre of volatile exchange rates. Nor has the long-term problem of limited access to credit amongst importers been resolved.Continue reading “Caution Prevails After the Summer Vacation – ITTO European Market Report 31st August 2011”", "pred_label": "__label__POS", "pred_score_pos": 0.7294189929962158}
{"content": "The law firm of Oakes & Fosher is presently investigating the alleged misconduct of former securities broker Leon Vaccarelli. According to his publicly available FINRA BrokerCheck report, Leon Vaccarelli has been the subject of multiple customer disputes.\nLeon Vaccarelli was a Connecticut base securities broker. He worked in the securities industry for seventeen years. During his career, he was registered with four different securities firms. He is no longer working as a registered securities broker in any fashion.\nHis Registrations Ameriprise Financial Services (1999-2007) IDS Life Insurance Company (1999-2006) QA3 Financial Corp. (2007-2011) The Investment Center (2011-2017) The Allegations\nIn August 2017, Leon Vaccarelli was sanctioned by the United States Securities and Exchange Commission. The findings in this matter state that he, through his business Lux Financial Services, misappropriated and misused investment funds he obtained from customers. He allegedly used various different methods to secure funds including; allegedly stealing from a trust fund for which he was the trustee, soliciting his customers from his affiliated firm ‘The Investment Center’ for additional funds while allegedly falsely representing it would be invested in their existing brokerage accounts, or even persuading customers to sell existing investments, like annuities, to fund purchases of notes. Vaccarelli allegedly secured over $1 million from nine different investors, most of whom were elderly. He then allegedly used these funds to pay for personal expenses. These civil charges are currently pending. Five suits were filed against Leon Vaccarelli’s former member firm due to his alleged fund conversion. These five suits were settled for a total of $641,728 in damages being awarded to the afflicted customers. In May 2018, Leon Vaccarelli was convicted on charges of mail fraud, wire fraud, and money laundering.\nWhat Does This Mean?\nConverting a customer’s funds is one of the most blatant and heinous act a securities brokers could ever commit–especially when they specifically target elderly investors. Investors spend their entire lives saving money for retirement and for a securities broker to just steal it out right from under them to fund their luxurious lifestyle is abhorrent. Securities firms are liable to afflicted investors for their losses, even after they have terminated the perpetrating party. Converting a customer’s funds is a crime committed while the broker is acting in the scope of their employment, which means their firms should be adequately monitoring their activities. Securities firms who fail to monitor its registered brokers to the necessary standard can cause investors to experience significant losses if their brokers are engaging in any unauthorized and potentially harmful activities.\nOakes & Fosher Can Help\nMany investors are unaware of the legal recourse available to them after losing money due to securities broker fraud and/or negligence. The truth is that investors who have lost money in this fashion may actually be entitled to damages. Oakes & Fosher dedicates its entire legal practice to helping investors across the nation. If you or someone you know, have lost money investing with Leon Vaccarelli, please contact Oakes & Fosher for a free and private consultation. Oakes & Fosher handles cases on a contingency basis, which means there are no fees charged unless we collect for you.", "pred_label": "__label__POS", "pred_score_pos": 0.7098667621612549}
{"content": "Self-assembly of diblock copolymers composed of a globular protein and a polymer provides a direct route towards nanopatterning proteins and enzymes at high densities while preserving protein activity. By effectively nanopatterning proteins, we have demonstrated that this technique aids in the fabrication of a variety of biocatalytic, bioelectronic, and biosensor devices with greatly enhanced sensitivity and selectivity. In these devices, the densely-packed protein domains serve as a site for efficient enzymatic reaction or analyte capture, while the polymer domains control diffusion into the films as a function of analyte size and chemistry.\nOur globular protein-polymer block copolymers are synthesized by covalently attaching a single monodisperse polymer to each protein molecule using site-specific chemistry. We utilize a combination of scattering and microscopy techniques to investigate the resulting self-assembled nanostructures in solution, bulk, and thin film samples. We also develop theories and perform simulations to understand of the dynamics of protein-polymer self-assembly, providing key insights into the phase behavior of these materials.\nHighlighted Publications\n1. Paloni, J. M., Dong, X. H., & Olsen, B. D. (2019). Protein–Polymer Block Copolymer Thin Films for Highly Sensitive Detection of Small Proteins in Biological Fluids. ACS sensors, 4(11), 2869-2878. Link\n2. Huang, A., Paloni, J. M., Wang, A., Obermeyer, A. C., Sureka, H. V., Yao, H., & Olsen, B. D. (2019). Predicting Protein–Polymer Block Copolymer Self-Assembly from Protein Properties. Biomacromolecules, 20(10), 3713-3723. Link", "pred_label": "__label__POS", "pred_score_pos": 0.8114179968833923}
{"content": "Documenting Sociopolitical Development via Participatory Action Research (PAR) With Women of Color Student Activists in the Neoliberal University\nThis is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.\nAbstract\nPolitical activism attests to the sociopolitical development and agency of young people. Yet the literature sparingly engages the intersectional subjectivities that inform the sociopolitical development of young people, especially women of color. Important questions remain in the theorizing of sociopolitical development among youth engaged in political activism within higher education settings. Thus, we focus on the following question: What experiences informed or catalyzed the sociopolitical development of women of color student activists within a racialized neoliberal university in the United States? In addressing this question we demonstrate how student-led participatory action research (PAR) within the neoliberal university can facilitate and support sociopolitical development. Of most value, this paper demonstrates how PAR can be used as a tool to support the intersectional sociopolitical development of student activists organizing within racialized neoliberal settings of higher education that threaten the academic thriving and overall wellbeing of students of color, specifically women of color. Sociopolitical development theorizing must engage elements of relational healing as a dimension of wellbeing. Therefore, our work contributes to these conversations by centering the experiences of women of color student activists.\nThis paper has been withdrawn.", "pred_label": "__label__POS", "pred_score_pos": 0.7330158948898315}
{"content": "2019/56, 8 July 2019\nOn 9 June, a much larger, steel-hulled Chinese fishing vessel hit a Filipino one near Recto Bank in the Philippine exclusive economic zone. Recto Bank is roughly 100 nautical miles from Palawan and 600 nautical miles from Hainan Island. The Chinese vessel abandoned the 22 Filipino fishermen to their fate in the dark night. A nearby Vietnamese fishing vessel, in accordance with customary maritime law, rescued the 22.\nThis incident shows that the Philippine state is unable to uphold its sovereign rights in the Philippine exclusive economic zone, and the constitutional requirement that “the State shall protect the nation’s marine wealth in its archipelagic waters, territorial sea, and exclusive economic zone, and reserve its use and enjoyment exclusively to Filipino citizens.” The Filipino vessel anchored on the country’s continental shelf was hit by a Chinese fishing vessel and the Filipino fishers were saved by a Vietnamese vessel. Neither of these two foreign vessels should have been there.\nMany states face serious capability constraints that make it impossible for them to effectively uphold their all their sovereign rights in all their exclusive economic zones. The Philippines as a middle-income archipelagic country with a large exclusive economic zone is clearly one of these.\nThe official explanations for the presence of the Chinese fishing vessel deep within the Philippine exclusive economic zone show that the Duterte administration is unwilling to uphold Philippine sovereign rights and the 1987 Constitution in the Philippine exclusive economic zone in the South China Sea. President Duterte has repeatedly said he is unable to do so against Chinese vessels as this could trigger war with China. Yet, many other states are enforcing their sovereign rights in their exclusive economic zones by apprehending, and even sinking Chinese vessels viewed as infringing upon these rights. So far none of these states has been attacked by China.\nPresident Duterte’s official spokesperson Salvador Panelo, in response to questions about 9 June, has stated that President Duterte in October 2016 reached a legally-binding verbal agreement with President Xi Jinping that the Philippines will not stop Chinese vessels fishing in the Philippine exclusive economic zone in the South China Sea. The Philippines’ inability to fully uphold its sovereign rights is an unfortunate reality. The Duterte administration’s unwillingness to do so in this case is an unfortunate choice.\nDr Malcolm Cook is Senior Fellow at the ISEAS – Yusof Ishak Institute.\nThe facts and views expressed are solely that of the author/authors and do not necessarily reflect that of ISEAS – Yusof Ishak Institute. No part of this publication may be reproduced in any form without permission.", "pred_label": "__label__POS", "pred_score_pos": 0.5298248529434204}
{"content": "At the end of 2019, USCIS announced plans to drastically increase filing fees for all applications. The plan, originally announced on November 14, 2019, has been on hold while the necessary comment and approval procedures take place. In December, the proposal was adjusted and the comment period was extended to account for the changes.\nToday, USCIS announced that the timeline for the fee increase has been pushed back once again. The comment period, originally set to end on December 30, has been reopened and extended until\nFebruary 10th. Any approved change will require 60 days notice before going into effect, which means that the fee increase will be implemented in mid-April at the earliest.\nIndividuals who are eligible to file petitions before April are encouraged to do so in order to avoid significant price increases. H1-B applicants may be affected by the new fees since the cap filing window will last 90 days this year.\nUSCIS has already received more than 29,000 comments on the proposed change and, once approved, it is expected that the fee increases will be challenged in court. One of the most controversial sections of the proposal is a new $50 fee for asylum applications. Adoption of a filing fee for those seeking asylum in the US would present a significant challenge for individuals in detention with no access to the funds.", "pred_label": "__label__POS", "pred_score_pos": 0.5183764696121216}
{"content": "The American College of Physicians (ACP) has long advocated for universal access to high-quality health care in the United States. Yet, it is essential that the U.S. health system goes beyond ensuring coverage, efficient delivery systems, and affordability. Fundamental restructuring of payment policies and delivery systems is required to achieve a health care system that puts patients’ interests first and supports physicians and their care teams to deliver high-value, patient- and family-centered care. The ACP calls for reform of U.S. payment, delivery, and information technology systems to achieve this vision. The ACP’s recommendations include increased investment in primary care; alignment of financial incentives to achieve better patient outcomes, lower costs, reduce inequities in health care, and facilitate team-based care; freeing patients and physicians of inefficient administrative and billing tasks and documentation requirements; and development of health information technologies that enhance the patient-physician relationship.\nRelated Posts First-Phase Insulin and Amylin after Bariatric Surgery: A Prospective Randomized Trial on Patients with Insulin Resistance or Diabetes after Gastric Bypass or Sleeve Gastrectomy.\nNovember 19, 2020\nEnhanced inflammasome activation and reduced sphingosine-1 phosphate S1P signalling in a respiratory mucoobstructive disease model.\nApril 28, 2020\nAdvertisement\nMeeting Coverage ACC 2020The American College of Cardiology decided to cancel ACC.20/WCC due to COVID-19, which was scheduled to take place March 28-30 in Chicago. However, ACC.20/WCC Virtual Meeting continues to release cutting edge science and practice changing updates for cardiovascular professionals on demand and free through June 2020. ENDO: 2020ENDO 2020 Annual Conference has been canceled due to COVID-19. Here are highlights of emerging data that has still been released. Keep an eye out for ENDO Online 2020, which will take place from June 8 to 22.", "pred_label": "__label__POS", "pred_score_pos": 0.8639619946479797}
{"content": "SAN DIEGO, November 19 /PRNewswire/ -- Accumetrics, Inc., developer of the VerifyNow System, the first point-of-care method for measuring platelet reactivity, announces that its market-leading VerifyNow P2Y12 Test was one of multiple methods evaluated in the POPular study, which was presented during a Late Breaking Clinical Trials session at the American Heart Association's annual Scientific Sessions. The VerifyNow P2Y12 Test is used to measure the antiplatelet effect of medications, such as clopidogrel (Plavix(R)), that reduce platelet reactivity by blocking the platelet P2Y12 receptor.\nThe POPular study is the first head-to-head comparison of multiple platelet function tests in predicting adverse events in patients undergoing elective coronary stenting. The study investigators mentioned that many of the tests for platelet reactivity evaluated in the study are either labor-intensive, have significant time constraints, or cannot be performed at the point-of-care. The investigators noted that the VerifyNow System does not have these limitations. The investigators also speculated that recent data may soon make platelet reactivity testing a routine clinical tool.\nWe are at a time when much attention has been drawn to antiplatelet medications, such as Plavix, and understanding the variability in patients' response to these medications. For example, patients who use certain heartburn medications or patients with a specific genetic disposition may not receive the desired platelet inhibiting effect of Plavix. These are only two of the many factors that may contribute to the variability in response to these life-saving medications. The VerifyNow P2Y12 Test can assist physicians by providing a direct measure of the antiplatelet effect in each patient so they can make more informed treatment decisions, said Timothy Still, president and CEO of Accumetrics.\nThe VerifyNow System is widely used in various clinical settings where antiplatelet medications are prescribed to reduce the occurrence of future thrombotic events such as heart attack and stroke.\nAbout Accumetrics (www.accumetrics.com)\nAccumetrics is committed to advancing medical understanding of platelet function and enhancing quality of care for patients receiving antiplatelet therapies by providing industry-leading and widely accessible diagnostic tests for rapid platelet function assessment.\nAccumetrics' VerifyNow System is the first rapid and easy to use platform to help physicians determine an individual's response to multiple antiplatelet agents. Addressing every major antiplatelet drug, including aspirin, P2Y12 inhibitors [e.g. prasugrel (Effient(TM)) and clopidogrel (Plavix)], and GP IIb/IIIa inhibitors [e.g. abciximab (ReoPro(R)) and eptifibatide (Integrilin(R))], the VerifyNow System provides a valuable tool to help physicians make more informed treatment decisions.\nThe Accumetrics logo and VerifyNow are registered trademarks of Accumetrics, Inc. ReoPro is a registered trademark of Centocor, Inc. Integrilin is a registered trademark of Millennium Pharmaceuticals. Plavix is a registered trademark of Sanofi-Aventis. Effient is a trademark of Eli Lilly and Company.\nSOURCE: Accumetrics, Inc.\nCONTACT: Megan Rusnack of Lippert/Heilshorn Associates, +1-212-838-3777,mrusnack@lhai.com, for Accumetrics, Inc.; or Timothy I. Still, Presidentand CEO of Accumetrics, +1-858-404-8260, press@accumetrics.com", "pred_label": "__label__POS", "pred_score_pos": 0.6879532337188721}
{"content": "Mar 14\nEvery woman has used the excuse “I’m PMSing” in their lifetime. However, recent studies show that PMS and PMDD aren’t just excuses but medical conditions that can have an impact on a woman’s daily life.\nWhat is PMS?\nPMS, or premenstrual syndrome, is a group of symptoms linked to the menstrual cycle. Though the length of time PMS occurs depends on the woman, the symptoms usually occur one to two weeks before menstruation begins. Some of the most common symptoms for PMS include:\nChronic fatigue\nIrritability and mood swings Headaches and backaches Trouble with concentration Anxiety and depression According to the American College of Obstetricians and Gynecologists, about 85 percent of women show at least one of these symptoms before menstruation. However, one in 20 women can suffer with a severe form of PMS, also known as PMDD.\nWhat is PMDD?\nAs previously stated, premenstrual dysphoric disorder (PMDD) is a severe form of PMS. The symptoms are similar to PMS, but are severe enough to interfere with work, social activities and relationships. PMDD is diagnosed by a physician if erratic mood swings, anger, fatigue, insomnia, tension and lack of interest in usual activities occur a week before and after menstruation.\nExercising\nMedications, such as hormone-based birth control and anti-depressants Counseling If you feel that your PMS or PMDD is impacting your daily life, consult your physician about treatment options.", "pred_label": "__label__POS", "pred_score_pos": 0.6734769344329834}
{"content": "Undocumented students contribute more than $10 billion in annual taxes, but the federal government refuses to grant them any federal relief aid during the COVID-19 pandemic. The lack of federal government intervention threatens their access to a college education and well-paid employment opportunities. This raises questions about equity that ultimately end up on states’ agendas already preoccupied with battling COVID-19.\nA postsecondary education “can translate into a net benefit of hundreds of thousands of dollars over one’s lifetime.” While the passage of DACA or Deferred Action for Childhood Arrivals has granted undocumented students access to better employment opportunities, DACA-recipients make up less than half of the undocumented student population. The benefits of DACA do not address the economic insecurity of non-DACA recipients, therefore exposing the limitations of current federal action and placing the future of undocumented students in the hands of states. With federal access to a guaranteed K-12 education, but not to a college education, undocumented students study, work, and live between the “extremes of legal and illegal.”\nAs undocumented students navigate the uncertainty associated with their legal status, states have attempted to help them attend college by offering them in-state rather than out-of-state tuition. New York is currently one of the nineteen states that have in-state resident tuition policies in effect. The price difference is significant: at City University of New York (CUNY), the out-of-state tuition rate at four-year colleges is $18,600 whereas the in-state rate is $6,930. Unfortunately, in-state resident tuition policies have shown to only minimally aid the financial costs of attending college, forcing many undocumented students to attend community colleges rather than four-year colleges due to their lower tuition rates, even if it did not form part of their academic plans.\nTo increase access to all higher education institutions, states have passed their own versions of the federal DREAM (Development, Relief, and Education for Alien Minors) Act, which failed to pass in Congress but would have granted undocumented youth a path to citizenship and federal financial aid benefits. Currently, 11 states have their own DREAM Acts, which tend to grant undocumented students access to state-funded financial aid and in-state tuition. Nonetheless, the failure of the federal DREAM Act’s passage is another, and perhaps the most notable example, of the government’s neglect and exclusion of undocumented students.\nWhile making up 200,000 of the front-line workforce in the United States during the pandemic, undocumented students are left to struggle to cover both tuition\nand non-tuition related costs if they do not live in a state with its own DREAM Act. Non-tuition related costs may include and go beyond transportation, food, and housing. If these costs are not met, they may lead to food insecurity and excessive working, especially for non-DACA recipients who are forced to rely on cash-only employment, and ultimately hinder college completion levels.\nUndocumented students must be on every state’s higher education reform agenda, especially as the federal government deliberately denies them any federal aid during the COVID-19 pandemic while the very universities they attend are getting up to $132.6 million. Since Congress is painstakingly slow at pushing forth another version of the DREAM Act or at including undocumented students in further stimulus talks, it is up to the states to prioritize the economic well-being of this population.\nStates without their own DREAM Acts should work on passing their own and those with already existing legislation should further evaluate what needs further improvement, including access to emergency grant funds, practical-skill building programs for graduating students entering the workforce, and food security initiatives on campuses. More than ever, undocumented students must secure their right to a postsecondary education, regardless of DACA status, and the work starts at the state level.\nIsmerlyn Gonzalez, a senior at Hunter College majoring in sociology with a minor in public policy, held one of two paid internships in the MDRC Judith Gueron Scholars Program this summer. While growing up in Harlem, Ismerlyn became quickly aware of the racial and socioeconomic disparities present in New York City’s education system. At Hunter, Ismerlyn coaches incoming freshmen as a Scholar Peer Leader. She is interested in pursuing a master’s degree in public policy to address inequities in education policy.", "pred_label": "__label__POS", "pred_score_pos": 0.8021539449691772}
{"content": "Sergey Sobolev Thank you for the insight!\nI agree and disagree. One the one hand, only committing to things that are “right for you” is powerful and effective, and we should focus on these areas (if we commit to something we’re not actually serious about, it’s a waste of energy and failure waiting to happen). I wholly agree — values precede commitments.\nOn the other hand, there are irrefutable principles that influence and govern “greatness” across humanity (in some goal areas). For instance, the “best version” of ourselves is healthy — emotionally, mentally, spiritually, and physically. The path to greatness always involves hard work, discipline, and commitment; even if these areas don’t interest you, you’ll need to subscribe to them eventually if you want to become the next stage of your personal evolution.\nThank you again for your feedback! I found it to be very valuable.", "pred_label": "__label__POS", "pred_score_pos": 0.8531791567802429}
{"content": "In last Tuesday’s State of the Union address, President Trump urged Congress to turn the White House’s framework into a bill. President Trump emphasized the “Four Pillar” plan in his speech, including: increasing border security funding ($25 billion trust fund for the border wall system), limiting family-based immigration sponsorship to only spouses and minor children, and terminating the diversity visa, in exchange for allowing 1.8 million DACA recipients to get legal status and eventually citizenship. It appears President Trump’s attempts at reaching a compromise on immigration will fail as Democrats booed at the mention of eliminating family reunification sponsorship for adult children, parents and siblings. Some Republicans were upset President Trump went back on his “no amnesty” pledge during his campaign.\nYesterday, Republican Senator John McCain and Democratic Senator Christopher Coons introduced a bipartisan compromise that would protect DACA recipients from being deported, provide a pathway to citizenship, alleviate the backlog in immigration courts, and provide new border security measures without funding for a wall. The legislation is a companion to a bill introduced by House representatives Will Hurd and Pete Aguilar which has 54 co-sponsors. However, President Trump tweeted that “[A]ny deal on DACA that does not include STRONG border security and the desperately needed WALL is a total waste of time.”\nSome Republicans have backed the bill proposed by House Judiciary Committee Chairman Bob Goodlatte last month. Representative Goodlatte’s bill is mostly in line with President Trump’s immigration plan.\nUltimately any bill or budget passed by Congress must be signed by the President.\nCongress and President Trump are under pressure to pass a budget, which may include a short-term or long-term solution to immigration by February 8 to keep the Federal government from shutting down. EIG will continue to diligently monitor the situation and provide real-time updates.", "pred_label": "__label__POS", "pred_score_pos": 0.6891322135925293}
{"content": "Conflict is sparks flying. It is emotions rising. It is experiencing what most of us think we would rather avoid. Yet, sometimes conflict is necessary. When we speak up for the slandered. When we defend the defenseless. When we risk our reputation to protect the innocent.\nBut our actions can only resolve part of the problem. The slandered might still feel worthless. The defenseless might still feel powerless. And, the innocent might still feel betrayed. These are reactions that continue to harm.\nConflict then shows us another face. It fights for the hearts that sink into despair. It fights against the lies that drag them there. Yes, conflict is sometimes called love.\nAn unsettling thought seeped into my mind. Someone didn’t respect me. Why? Because I didn’t meet up with their personal expectations.\nI looked out the window, stunned. Should I inform them of my inherent worthiness? Grieve at my helplessness in the situation? Or slam the door and walk away?\nA verse came to mind. Jesus\n“was despised and rejected…, a man of sorrows and acquainted with grief.” (Isaiah 53:3) Yes, he grieved, but it didn’t change his attitude. He said, “As the Father has loved me, so have I loved you.” (John 15:9)\nIt really can be a domino effect. Jesus treated everyone with dignity and respect, just like God treated him. We can do the same, even if we have to walk away.", "pred_label": "__label__POS", "pred_score_pos": 0.7385727763175964}
{"content": "Welcome to Gene Therapy Patient Engagement Gene Therapy Patient Engagement is dedicated to providing detailed case studies and actionable insights on how to incorporate patient input more effectively into gene therapy development. Whilst everyone knows the patient is important, it’s evident that there are several unique nuances within gene therapy where a lot can be learned from those who have been through the experience, including: Discovering the Tools Being Used to Create and Distribute Educational Materials on Gene Therapy Understand the strategies behind developing virtual resources and reaching patients in the context of the current pandemic, with insights from Amicus Therapeutics & uniQure Integrating Patient Input More Effectively in Clinical Trial Design Hear how Lysogene and AGTC are incorporating patient input into clinical trial design, through designing of bespoke clinical endpoints that are meaningful to patients and regulators, and developing patient advisory boards and councils to support this process Navigating the Challenges Around the Realities of Committing to a Gene Therapy TrialExplore the ways that remote-based clinical assessments can be used to support long-term patient commitment required for gene therapy trials, and explore how to manage and align expectations aross stakeholders, with insights shared from Nationwide Children’s Hospital, GenSight Biologics& bluebird bio Forging Mutually Beneficial, Long-Lasting Partnerships with Patient Advocacy Organizations Discover the ways in which patient advocacy groups and industry have collaborated on gene therapy development, with insights from CureDuchenne & Pfizer Investigating Early Stage Patient Engagement and its Importance for Gene TherapyHear how FARAare preparing their patient communities early in light of potential gene therapies entering the pipeline, and understand how Takedaare engaging patients in R&D to truly understand their disease and set up strong foundations for later stage development", "pred_label": "__label__POS", "pred_score_pos": 0.9443213939666748}
{"content": "Abstract\nThe production of melanin significantly enhances the virulence of many important human pathogenic fungi. Despite fungal melanin's importance in human disease, as well as melanin's contribution to the ability of fungi to survive in diverse hostile environments, the structure of melanin remains unsolved. Nevertheless, ongoing research efforts have progressively revealed several notable structural characteristics of this enigmatic pigment, which will be the focus of this review. These compositional and organizational insights could further our ability to develop novel therapeutic approaches to combat fungal disease and enhance our understanding of how melanin is inserted into the cell wall.\nKeywords Cryptococcus Fungal virulence Fungi Melanin Structure ASJC Scopus subject areas Microbiology Microbiology (medical)", "pred_label": "__label__POS", "pred_score_pos": 0.9524791836738586}
{"content": "How to Fund Cancer Treatment\nEvery day, thousands of people just like you, are asking themselves:\n“\nHow am I going to pay for cancer treatments?”\nIf you've been diagnosed and decided to pursue traditional/alternative treatment, most health insurance companies cover a limited portion of the cost for treatments, forcing individuals to pay exorbitant out-of-pocket costs.\nThere is an option available to help individuals so these financial responsibilities are not overwhelming.\nConsider a Viatical Settlement\nThis somewhat unknown financial service is designed specifically for individuals who have been diagnosed with cancer or a chronic disease or health condition.\nA\nViatical Settlement involves the sale of your Life Insurance policy to a third-party institution for immediate cash. While the amount offered for a policy will vary depending on the insured’s health condition and the provisions set forth in the Life Insurance policy; individuals may receive up to 70% of the face value of their policy.\nAll types of Life Insurance policies are considered: Whole Life, Term Life, Group Term, FEGLI, Universal and Variable Life.\nHow To Fund Cancer Treatment With a Viatical Settlement\nWhile most people apply the proceeds from a Viatical Settlement to fund their cancer treatment, the proceeds may be used for a multitude of personal reasons. Perhaps you wish to spend quality time with family, to supplement income, or to plan future financial matters.\nIn some instances, the proceeds from the sale of a Life Insurance policy are tax-free*.\nThe Right Approach for You\nIs a Viatical Settlement the right approach for you?\nA Viatical Settlement option should be explored, especially if it is needed to fund the high cost of cancer treatment.\n*HIPAA Act, 1996", "pred_label": "__label__POS", "pred_score_pos": 0.6755733489990234}
{"content": "Here we advance the protection of split manufacturing (SM)-based layouts through the judicious and well-controlled handling of interconnects. Initially, we explore the cost-security trade-offs of SM, which are limiting its adoption. Aiming to resolve this issue, we propose effective and efficient strategies to lift nets to the BEOL. Towards this end, we design custom 'elevating cells' which we also provide to the community. Further, we define and promote a new metric, Percentage of Netlist Recovery (PNR), which can quantify the resilience against gate-level theft of intellectual property (IP) in a manner more meaningful than established metrics. Our extensive experiments show that we outperform the recent protection schemes regarding security. For example, we reduce the correct connection rate to 0% for commonly considered benchmarks, which is a first in the literature. Besides, we induce reasonably low and controllable overheads on power, performance, and area (PPA). At the same time, we also help to lower the commercial cost incurred by SM.", "pred_label": "__label__POS", "pred_score_pos": 0.9712767601013184}
{"content": "Authors:\nDeborah Wessels, Daniel F. Lusche, Edward Voss, Spencer Kuhl, Emma C. Buchele, Michael R. Klemme, Kanoe B. Russell, Joseph Ambrose, Benjamin A. Soll, Aaron Bossler, Mohammed Milhem, Charles Goldman, David R. Soll\nSummary:\nUsing unique computer-assisted 3D reconstruction software, it was previously demonstrated that tumorigenic cell lines derived from breast tumors, when seeded in a 3D Matrigel model, grew as clonal aggregates which, after approximately 100 hours, underwent coalescence mediated by specialized cells, eventually forming a highly structured large spheroid. Non-tumorigenic cells did not undergo coalescence. Because histological sections of melanomas forming in patients suggest that melanoma cells migrate and coalesce to form tumors, we tested whether they also underwent coalescence in a 3D Matrigel model. Melanoma cells exiting fragments of three independent melanomas or from secondary cultures derived from them, and cells from the melanoma line HTB-66, all underwent coalescence mediated by specialized cells in the 3D model. Normal melanocytes did not. However, coalescence of melanoma cells differed from that of breast-derived tumorigenic cell lines in that they 1) coalesced immediately, 2) underwent coalescence as individual cells as well as aggregates, 3) underwent coalescence far faster and 4) ultimately formed long, flat, fenestrated aggregates that were extremely dynamic. A screen of 51 purified monoclonal antibodies (mAbs) targeting cell surface-associated molecules revealed that two mAbs, anti-beta 1 integrin/(CD29) and anti-CD44, blocked melanoma cell coalescence. They also blocked coalescence of tumorigenic cells derived from a breast tumor. These results add weight to the commonality of coalescence as a characteristic of tumorigenic cells, as well as the usefulness of the 3D Matrigel model and software for both investigating the mechanisms regulating tumorigenesis and screening for potential anti-tumorigenesis mAbs.\nSource:\nPLOS ONE; 2017, 12 (3): e0173400", "pred_label": "__label__POS", "pred_score_pos": 0.7761760354042053}
{"content": "ArticlesbyS. J. Wilson\nTotal Records (2 ) forS. J. Wilson\nA. Foo J. Y.and S. J. Wilson Studies have demonstrated that a notable increase in arterial stiffening can signify the presence of cardiovascular abnormalities, such as hypertension. Presently, the mercury sphygmomanometer continues to be the clinical gold standard to identify such abnormalities, but due to its measuring nature it cannot be used for continuous observation. Pulse transit time (PTT), which has an inverse relationship with blood pressure (BP), is proposed here as a simple and non-invasive technique to monitor hypertension in children. In order to minimize inter-subject PTT differences, all obtained PTT data were normalized to the study population. The results indicated that normalized mean PTT value is able to differentiate hypertensive from normal children in a significant ( p < 0.01) manner in both upper and lower limbs. Preliminary findings herein suggest that PTT can be useful tool to monitor for hypertension in children especially during prolonged clinical observations.\nJ. Y. A. Foo and S. J. Wilson A simple and non-invasive technique, termed pulse transit time (PTT), has shown its potential in long-term investigations such as respiratory sleep studies and cardiovascular studies. Based on these findings, the PTT technique shows relevance for continuous haemodynamic monitoring in critical care. The objective of this review is to understand the potential, applications and limitations of PTT in this clinical setting. Present non-invasive haemodynamic monitoring methods such as automated oscillometric blood pressure (BP) and auscultatory techniques have their known limitations. They tend to underestimate systolic BP while overestimating diastolic BP. Due to the periodic increase in cuff pressure cycles during data acquisition, these techniques may cause much discomfort in elderly geriatric patients, or lessen the cooperation of younger paediatric patients. Thus, there can be adverse effects on therapeutic decisions and possibly clinical outcomes. Documented evidences have indicated that changes observed in PTT are inversely correlated to the corresponding BP changes. In critical care, a simple and accommodating technique like PTT may be useful in providing better comfort for patients during extended monitoring. Being a semi-quantitative measure, blanket recommendations for its utility can then become possible. The basic instrumentations needed are often part of standard critical care monitoring system. Furthermore, PTT also has the potential to monitor the often tachypnoeic respiratory dependent BP changes seen in small infants during critical care.", "pred_label": "__label__POS", "pred_score_pos": 0.5903899669647217}
{"content": "Stanley Cohen coined the term moral panics and deviancy amplification False reporting is best understood as exaggerated reports out of all proportions Such incidents are common with what are termed ‘red-top’ newspapers who have high or mass circulation figures or ‘clicks’ on their websites. Tabloid newspapers are The Sun, The Mirror etc. While high traffic news websites are the Daily Mail These newspapers often over dramatise events creating moral panics over certain issues Mc Robbie and Thornton argue media-generated moral panics are less common due to new media (social networks) posts often challenging moral panics with alternative views (pluralism) However many Facebook feeds are criticised for publishing ‘false-news’ or what is now more commonly known as ‘fake-news’.", "pred_label": "__label__POS", "pred_score_pos": 0.7872258424758911}
{"content": "Teams from Oliver, Morton, Stark-Billings, Golden Valley, Mountrail and Pembina counties took top honors in the second state 4-H livestock quiz bowl held at North Dakota State University.\nThe contest provides an opportunity for youth enrolled in the North Dakota 4-H livestock project to demonstrate their knowledge of animal science-related subject matter in a friendly, yet competitive, setting.\nYouth were tested on all food animal livestock species: beef, dairy, swine, goat (dairy and meat), sheep, poultry and rabbit. The 4-H’ers also fielded questions about Youth for the Quality and Care of Animals, a national multispecies quality assurance program for youth ages 8 to 21, with a focus on three core pillars: food safety, animal well-being and character development.\nFifty-five youth representing six North Dakota counties completed in the quiz bowl.\nSenior Division\nThe top teams were:\nFirst - Oliver County 4-H, with team members Jacob Klaudt, Rebecca Schmidt, Morgan Miller and Reanna Schmidt Second - Morton County 4-H, with team members Cooper Strommen, Cassidy Strommen, Sheridan Ellingson and Medora Ellingson Third - Golden Valley 4-H, with team members Chance Manhart, Abby Hecker, Kade Manhart and Kinze Steiner\nIndividual winners:\nFirst - Klaudt Second - Taylor Downing, Stark-Billings County 4-H Third - Morgan Vachal, Mountrail County 4-H Fourth - Kade Manhart Fifth - Hecker\nIntermediate Division\nThe top teams were:\nFirst - Stark-Billings County 4-H, with team members Ian Dohrmann, Coy Melchior, Abby Talkington, Trevor Lefor and Emma Bock Second - Golden Valley County 4-H team No. 1, with team members Dillon Manhart, Abe Oech, Levi Hecker and Harley Feiring Third - Pembina County 4-H, with team members Gracee Thorlakson, Ava Kemnitz, Remington Larson, Wyatt Larson and Colbie Furstenau\nIndividual winners:\nFirst - Gust Twedt, Golden Valley 4-H Second - Erika Littlefield, Mountrail County 4-H Third - Thorlakson Fourth - Kemnitz Fifth - Manhart\nJunior Division\nThe top teams were:\nFirst - Stark-Billings County 4-H, with team members Hadley Talkington, Layne Melchior, Sawyer Wolf and Kylee Sickler Second - Golden Valley County 4-H, with team members Josh Davidson, Bronson Manhart, Taylor Feiring and Gus Ueckert\nIndividual winners:\nFirst - Talkington Second - Davidson Third - Melchior Three way tie for fourth - Manhart, Sickler and Wolf\nTeams competed by giving oral answerers to questions posed by a moderator. Each match had a one-on-one phase, a team phase and a toss-up phase with bonuses attached to questions.\nNDSU Agriculture Communication - March 16, 2020\nSource: Leigh Ann Skurupey, 701-231-6658, leighann.skurupey@ndsu.edu Editor: Ellen Crawford, 701-231-5391, ellen.crawford@ndsu.edu", "pred_label": "__label__POS", "pred_score_pos": 0.9180672764778137}
{"content": "For a better experience, keep your browser up to date. Check here for latest versions.\nMarch 18, 2020\nAs an Indigenous social enterprise and digital agency, we need to manage — what may often seem like — contradictory and opposing concepts, worldviews, and ideas that are challenging to navigate in our day-to-day work. Some of these include:\nWe are often faced with choices that might appear to be an \"either-or\" dilemma. However, considering a \"both-and\" perspective may amplify the best of both worlds to determine the most creative and collaborative solution. At Animikii, we are consistently presented with the question of how we\nmanage polarity.\nWe were introduced to the concept of Polarity Management by Teara Fraser when we were describing our social enterprise as the\nwings of a bird. Teara put together a leadership challenge based on Animikii in partnership with Royal Roads University, where eight teams in the Masters of Arts in Leadership Program worked together to develop presentations that provided strategic recommendations for Animikii to support our growth. A similar theme amongst the responses was managing polarity. We connected with this perspective and wanted to share our thoughts on what it is and how it relates to what we do at Animikii.\nThere are existing frameworks, ideas, worldviews, and metaphors that can be helpful when thinking about managing polarity, including:\nWe describe polarity at Animikii as the two wings of a bird, interdependent and interconnected, with both needed for flight to be possible. By acknowledging this interdependence, we can manage the polarity of our social enterprise and strive for the best aspects of both perspectives (while avoiding the limitations of each).\nOne of Animikii’s toughest challenges is balancing our organizational sustainability as a business while also maintaining and scaling our social impact. Both efforts can appear distinct; however, understanding and managing their interconnected relationship is essential to maintaining our success. We wouldn’t operate our business without our social impact focus. Yet, we cannot sustain meaningful impact without the support that comes from our revenue generation, business operations, and economic viability.\nThe very term “social enterprise” contains its own polarity between the words “social” and “enterprise”. Its use is gaining popularity in the business community, though definitions and descriptions may vary. Yet, there are innovators around the world who find a way to manage this polarity. Indeed, while managing our own polarity, we’ve felt the strain of balancing our impact and our business goals. For example, some years we gave back so much that it affected our profitability. Other years, we funnelled excess revenues into scaling our impact. Over the last couple of years, our team has given back over a thousand hours into meaningful, community-focused initiatives.\nSince then, we’ve realized that maintaining a balance between profitability and giving back within our social enterprise is necessary for us to stay healthy and continue to grow. The Royal Roads leadership challenge nudged us to formalize our structure, operations, and mental model of how we see ourselves. One of the proposals expanded upon our “wings of a bird” analogy to the full body that represents our structure. This resonated with us (for obvious reasons) and resulted in us using the following image to explore and describe our governance.\nThis image is a Thunderbird and it illustrates how we see our organizational structure. The image comes from our 2017 Social Impact Report, illustrated by Animikii lead designer, Mark Rutledge. It has become the visual representation to help describe our structure internally with staff as well as externally with partners, customers, and the public.\nTo guide the bird, it needs a mind to make the complex cognitive, analytical, and experiential decisions required to calculate flight. This is the role of the Board of Directors who are accountable for these functions.\nTo take off, and maintain flight, the bird needs two equally powerful wings. One wing shows the profitable operations that ensure our organizational sustainability as a business. The other wing represents our social impact efforts and what we aim to achieve as a social enterprise. Balance is required between both wings to maintain flight. While one wing could be more powerful, other parts of the bird would need to be able to make corresponding adjustments. Too much imbalance and the bird may not be able to fly.\nTo keep the bird healthy, energized, and alive, it needs a strong heart. This is where our people and impact circle contributes, guided by our Values.\nThe tail feathers are like the rudder of a boat or aircraft. They steer, maneuver, and provide stability for take-off and landing. This is in line with our approach to servant leadership and leading from behind.\nHolistically, we create spaces for the mind, heart, wings, and tail of the business through this analogy of a bird in flight. Each of these individual components maintains key roles in our organizational resilience. Collectively, this allows us as Animikii, the Thunderbird, to create energy and thunder through the flight of our social enterprise.\nThere are several tools that we deploy at Animikii to ensure our integrity as we scale. The bird analogy is one of those tools. It encapsulates other aspects of who we are, like our Impact Circle governance, and our connection to our Values.\nWe’ve grown quickly as a team. From two to five, then 10 people and it won’t be long until we’re up to 20. How do we effectively scale-up our organization with integrity when we’re over 100 people? What about 1,000? If we pursue profit at the expense of our social impact, it could put the foundation of our model and identity at risk. Having the appropriate internal concepts, tools, and methodologies will help us scale with integrity.\nThe bird analogy is appropriate in the context of Animikii because our name means Thunderbird in Ojibwe. This analogy works for us in managing polarity; however, this may be a good fit for other social enterprises as well.\nLet us know what you think! In the meantime, we’ll leave you with this stunning visual of birds flying together in a murmuration. These birds follow the same rules that we do:\ndon’t crowd, fly to the center, and don’t crash. March 18, 2020\nOur team handpicks Indigenous-focused news articles every week and provides you with a weekly digest. AND you'll also never miss another Animikii article (like this one).\nOne e-mail on Wednesdays. Unsubscribe anytime.", "pred_label": "__label__POS", "pred_score_pos": 0.5017865896224976}
{"content": "New York’s out, the USDA is in… What’s Next for Hemp Growers? On November 1st, over 700 New York hemp growers will have their licenses expire and replace by a new federal regulatory structure administered by the USDA. Background\nOn August 14th, Commissioner Richard A. Ball sent out two letters on behalf of the Department of Agriculture & Markets (DAM) to the USDA. These letters detailed the relationship between NYS and the USDA as the Interim Final Rule (IFR), the USDA’s legislation to oversee hemp cultivation federally, comes into effect on October 31st of this year. These letters state that New York State has decided\nnot to submit a state plan to the USDA. This decision will ultimately transfer authority over licensing and compliance from the NYS DAM to the USDA. Four years ago, the NYS DAM embarked on its industrial hemp pilot research program in accordance with the 2014 Farm Bill. According to the regulations of the Farm Bill, the USDA released its Interim Final Rule regarding the federal cultivation of industrial hemp late last year, set to replace the Farm Bill this year. Under the IFR, states can submit individual hemp cultivation plans which would operate independently from the USDA. This would allow states to maintain control over their hemp industry, including setting appropriate testing requirements, licensing, and enforcement of regulations. Many states have chosen to submit their own plans as the IFR has been sharply criticized for its out-of-touch and overburdensome regulations. Regulations regarding the timing of sampling and testing, disposal of non-compliant plants, and reporting requirements were specifically listed as problematic in New York’s letters to the USDA. Other lawmakers, such as NY Senator Chuck Schumer and Oregon Senator Ron Wyden have also released statements criticizing the IFR and its potential negative effects on the nation’s growing hemp industry. What This Means\nIn light of these circumstances, New York State has chosen\nnot to submit a state plan to the USDA for the 2021 growing season. Instead, the state has formally requested that the USDA extend the 2014 Farm Bill until the 2021 growing season, giving states more time to prepare and submit comprehensive plans in line with USDA regulations. Lawmakers also hope that this extension will allow the USDA to review and revise some of its more burdensome regulations, which they have failed yet to do.\nUnless the 2014 Farm Bill is extended or the USDA otherwise agrees to change its requirements for the 2021 grow season, it appears that growers interested in cultivating an industrial hemp crop in 2021 will need to apply to USDA for a producer license. NYS DAM has stated that they will do whatever they can to assist growers in this process should this be the case.\nGiven the USDA’s track record and responsiveness to criticisms of its final rule, it is not certain how they will respond to New York’s requests. Licensed hemp growers in New York State should prepare themselves for this transfer of authority and educate themselves on the tenets of the IFR should this be the case, as it differs greatly from established New York regulations.\nIssues with the Interim Final Rule\nThe IFR sets unrealistic standards for hemp cultivation. For example, while NYS tests for delta-9 THC alone, the USDA calls for the total THC content of the hemp plant, which also includes THCA. Further, it would require tests to come from the top flowers of the plant, which are naturally higher in THC. Based on anecdotal knowledge and experience, most New York hemp producers would have failed in 2019 under the proposed USDA testing regulations.\nThe IFR also sets strict regulations regarding disposal of non-compliant products. The USDA requires that, if one plant is found to not be in compliance with regulation, the entire crop must be destroyed. Given the nature of its testing requirements, this can be extremely harmful to growers who are otherwise cultivating compliant crops.\nUnder the IFR, inspections are conducted on an annual basis and with random samples. These inspections must be carried out within 15 days of the anticipated harvest date by a licensed official. This short timeline is unrealistic for many hemp growers and overestimates the capacity of state authorities to conduct accurate and thorough tests within such a short time period.\nAnother area of criticism concerns background checks; the IFR licensing process would require criminal background checks to ensure employees and “key figures” in business entities are free of drug convictions for a period of ten years. The USDA hemp producer application (which will replace NYS’s industrial hemp grower application), can be found here.\nWhat’s Next for NY Hemp Growers\nThe letters sent by the Department represent the first clear steps New York has taken to adjust to this interim final rule. The USDA’s response remains to seen. Although the IFR is certainly less than ideal, NYS growers should prepare for a transfer of authority to the USDA this October. This would require applying for the USDA hemp producer application, which will replace NYS’s industrial hemp grower application. This application can be found here.\nIf, however, the USDA does in fact extend the 2014 Farm Bill, hemp growers in NYS can expect business-as-usual for the 2021 growing season. During this time, the state would likely continue to work with the USDA to revise some of the IFR’s regulations.\nThe exact nature of this process can not yet be determined. Certain issues, such as what might happen to indoor growing operations during this limbo period, remain unclear. If the USDA does not extend the 2014 Farm Bill, hemp growers should expect further guidelines from the USDA as October 31 approaches. NYS DAM is also likely to release guidelines and assistance for New York growers.\nAs NYS continues to feel the economic, social, and political ramifications of the Covid-19 pandemic, legislative developments for cannabis within the state have been mostly placed on the sideline. Unless the USDA extends the 2014 Farm Bill allowing NYS more time to draft a comprehensive state plan, growers should not expect much to change regarding the regulations found in the interim final rule.\nJoe Vitale, Lead Policy Analyst\nJoe Vitale earned his bachelor’s degree in History and German Studies from Binghamton University, where his academic work has led to various awards, research positions, and publications in scholarly journals. Combining his vast research experience with a fine eye for details, Joe delivers in-depth regulatory analysis and compliance research at CCG.", "pred_label": "__label__POS", "pred_score_pos": 0.5671639442443848}
{"content": "ESG resilience during the Covid crisis: Is green the new gold?\nThe resilience of Environmental, Social, Governance (ESG) funds is not completely new. During the Covid-19 crisis – which clearly has strong social and environmental implications – investors perceived their strong performance as a defensive characteristic and cumulative flows continued to increase while massive sales occurred in traditional funds.\nThe analysis is this commentary shows that investors’ preference for ESG compared to conventional funds has not lessened – quite the opposite, in fact. At the EU level, the focus on ESG is likely to remain strong for asset managers and institutional investors. On a policy level, this has been supported so far by the Action Plan on Sustainable Finance and will continue with the upcoming Renewed Strategy.\nJean-Jacques Barbéris is Head of Institutional and Corporate Clients Coverage at AMUNDI. Marie Brière is Head of Investor Research Center at AMUNDI, Affiliate Professor at Paris Dauphine University and Member of the ECMI Academic Committee.", "pred_label": "__label__POS", "pred_score_pos": 0.643832802772522}
{"content": "Gay and Afraid: What South Korea Taught Us About the Dangers of Contact Tracing\nSouth Korea’s rapid response to the COVID-19 pandemic attracted worldwide praise, establishing the country as a blueprint for successfully containing the virus through contact tracing and mass testing. Although South Korea has managed to keep its daily case increase low and 10,194 out of a total 11,165 cases have so far recovered, an ongoing threat of clusters originating from so-called “super-spreaders” remains. This threat has pushed South Korea into more innovative and invasive digital contact tracing methods, such as gaining access to GPS records and card transactions to alert the public to possible exposure. Many human rights groups have underlined possible issues related to further rollouts of invasive digital tracing methods, particularly how negligence toward privacy in the instrumentalization of personal data could pose a danger to minority groups, more specifically to the LGBTQ+ community.\nContact Tracing; a Palpable Danger for LGBTQ+ Individuals\nOn May 2nd, a 29–year–old man who tested positive for the virus reportedly visited multiple clubs in Itaewon, South Korea, an area known in Seoul for its LGBTQ+ nightlife. This instantly raised fears that thousands may have been at risk of contracting the virus. As information regarding the cluster was released to the public, many media outlets described the venues as “gay clubs” and attempted to specify the age, occupation, and even identities of these 5,500+ at-risk individuals. As the LGBTQ+ community became an easy scapegoat for this cluster of cases, some of these individuals could not be immediately contacted, refusing to disclose themselves out of fear of persecution.\nA similarly angled narrative was pushed early on in February, instead surrounding a “super-spreader” from what was described in the media as a “cult,” with the ensuing backlash serving as an early warning on the dangers of pointing fingers at specific groups. The LGBTQ+ community’s implication to the most recent cluster resulted in calls to close down these clubs, along with reports of multiple individuals, with no direct correlation to the May 2nd outbreak, having their personal data leaked through gay dating apps like Grindr.\nSouth Korean Prime Minister Chung Sye-Kyun asked the public to avoid “criticizing a certain community as it will not help efforts to contain the coronavirus spread”; not going as far as explicitly acknowledging the particular risk to the LGTBQ+ community. That being said, scapegoating is not a new occurrence for the LGBTQ+ community — members have long fallen prey to ill-informed medical discrimination and prejudice — often as a result of the stigma surrounding the AIDS epidemic.\nIn a socially conservative country such as South Korea, where there is an absence of comprehensive anti-discrimination laws that protect LGBTQ+ individuals, a virus that does not discriminate can easily become a catalyst to deepen existing societal prejudices.\nContact tracing in the era of COVID-19 and the legacy of the AIDS epidemic\nThe LGBTQ+ community has faced a history of institutionalized medical stigma as a result of the AIDS epidemic, with its ongoing legacy of societal and health consequences felt worldwide. According to Chenard, LGBTQ+ individuals suffer from a “dual stigma.” They are more likely to be HIV positive and disproportionately suffer from homelessness, depression, and suicide because of discrimination, among other factors. Although the current pandemic concerns an entirely different virus, data collected from state-sponsored contact tracing tactics used to contain COVID-19 can become politicized much like the AIDS epidemic.\nBy attributing the outbreak to “gay clubs,” South Korean media outlets have played into a narrative that scapegoats a community already facing institutionalized medical and professional discrimination. The LGBTQ+ community is an easy target for those that already believe such a “lifestyle” is immoral, fitting into a storied narrative allowing individuals to deflect blame onto an already marginalized group. Not only is this narrative dangerous because it encourages discrimination towards LGBTQ+ individuals, it also undermines health initiatives by inhibiting the testing of individuals that have come in contact with confirmed cases because of their fear of persecution.\nDue to the politicization of personal data, advice from health experts must now compete with misinformation. In light of this, as other countries look toward implementing contact tracing apps as a “be all end all” solution to social distancing, they must consider — regardless of other benefits or their intentions — how the dissemination of personal data inevitably puts LGBTQ+ individuals at risk. Governments must not be complicit in allowing media outlets to push narratives based on data that individuals have provided, especially when dealing with a community that has long suffered as a scapegoat because of such institutional negligence.\nWhat efforts can be made to protect minority groups?\nHow should LGBTQ+ individuals worldwide feel comfortable giving states access to their personal data and permission to disseminate it freely? Although South Korea and other countries, like the UK, are opting for a centralized system of digital contact tracing — where anonymous data collected from bluetooth devices is stored on a central computer server — countries like Germany, Switzerland, and Austria have pursued a more decentralized approach. In developing a decentralized system of contact tracing, Apple and Google argue that transferring data directly between bluetooth devices would limit the power of hackers or governments to harness private data from a central server, possibly at the expense of having a more accurate account of COVID-19’s spread.\nThis brings us to a central dilemma. Does valuing individual privacy and security necessarily come at the expense of public health? If minority groups that have experienced institutionalized discrimination do not trust that these apps will protect their privacy, then unless it is made compulsory — like in South Korea — many will refuse to use them. Having established the consequences of mandatory contact tracing on the LGBTQ+ community in South Korea, is this a model that other countries should wish to replicate?\nWith estimates in the UK saying that these apps would need at least 60 per cent national usership to be effective, the cost of alienating minority groups is greater than just their fear of persecution. Fear also affects a state’s ability to track and contain future clusters in the hopes of ending social distancing. British Health Secretary Matt Hancock argued that “we cannot afford to not use [contact tracing apps],” and that “all data will be handled according to the highest ethical standard.” Others argue that invasive technology is not necessary for effective contact tracing, with countries such as Iceland emphasizing a more secure manual process.\nIn the interest of both minority groups’ security and each state’s COVID-19 containment initiatives, efforts are needed to strike a balance between individual privacy and maintaining the effectiveness of digital contact tracing apps.\nEdited by Gracie Webb", "pred_label": "__label__POS", "pred_score_pos": 0.7126492857933044}
{"content": "Bank Complexity, Governance, and Risk\nBank holding companies (BHCs) can be complex organizations, conducting multiple lines of business through many distinct legal entities and across a range of geographies. While such complexity raises the costs of bank resolution when organizations fail, the effect of complexity on BHCs' broader risk profile is less well understood. Business, organizational, and geographic complexity can engender explicit trade-offs between the agency problems that increase risk and the diversification, liquidity management, and synergy improvements that reduce risk. The outcomes of such trade-offs may depend on bank governance arrangements. We test these conjectures using data on large U.S. BHCs for the 1996-2018 period. Organizational complexity and geographic scope tend to provide diversification gains and reduce idiosyncratic and liquidity risks while also increasing BHCs' exposure to systematic and systemic risks. Regulatory changes focused on organizational complexity have significantly reduced this type of complexity, leading to a decrease in systemic risk and an increase in liquidity risk among BHCs. While bank governance structures have, in some cases, significantly affected the buildup of BHC complexity, better governance arrangements have not moderated the effects of complexity on risk outcomes.\nWe thank Inaki Aldasoro, Robert DeYoung, Krzysztof Gajewski, Lukasz Kamil Kurowski, Katheryn Russ, and seminar participants at the European Central Bank, George Mason University, the IBEFA Annual Meeting in San Diego, MoFiR, and workshop participants at the 4th Annual Chapman Conference on Money and Finance and the IBRN meeting hosted by the Federal Reserve Bank of New York. Mary Chen, Sarah Ngo Hamerling, and Kevin Lai provided excellent research assistance. Scott Okrent provided invaluable help in computing the systemic risk measures using the code facilitated by the VLab at New York University. The views in this paper are solely the responsibility of the authors and should not be interpreted as reflecting the views of the Board of Governors of the Federal Reserve System, the Federal Reserve Bank of New York, any other person associated with the Federal Reserve System, or the National Bureau of Economic Research.", "pred_label": "__label__POS", "pred_score_pos": 0.8496799468994141}
{"content": "The philosophy behind Naturopathic medicine is to treat the person, not the disease. Naturopathic Doctors focus on identifying the root causes of symptoms and addressing health concerns using natural therapies. We can help treat both chronic and acute conditions by creating a personalized plan for each patient’s unique needs. Our ultimate goal is to identify and address the root cause of your health concerns, to help you achieve your personal health goals.\nIn order to be certified as a Naturopathic Doctor, you must first retain a 4-year undergraduate degree before applying to a 4-year accredited Naturopathic medical school. The first 2 years are similar to conventional medical school and are more focused on clinical sciences, such as Anatomy, Physiology, Biochemistry and Pathology. Classroom studies include a variety Naturopathic topics, such as:\nTraditional Asian Medicine Nutrition Botanical Medicine Homeopathy Orthopaedic Assessments Counselling Orthomolecular Medicine\nNaturopathic doctors are strictly regulated by the College of Naturopathic Physicians of British Columbia (CNPBC). To be licensed as a Naturopathic Physician, applicants must pass two sets of licensing boards, regulated by the North American Board of Naturopathic Examinations (NABNE). Additionally, they must graduate from 1 of the 7 accredited schools in North America.", "pred_label": "__label__POS", "pred_score_pos": 0.6239523887634277}
{"content": "A top official of the Bank of International Settlement (BIS) disclosed that the institution would be collaborating with the Swiss National Bank (SNB) to trial a Central Bank Digital Currency (CBDC) later this year.\nBenoît Cœuré, head of the BIS Innovation Center, made this known at the Bund Summit held in Shanghai yesterday as published by local media outlet The Paper.\nAccording to Cœuré, the proof-of-concept CBDC scheduled to launch by the end of this year will help identify the elements needed for a retail CBDC.\nThese elements include connections to existing payment systems, digital identity tracks, compliance monitoring, among others.\nCœuré revealed at the event that in the future, the BIS would work with other central banks, including the Hong Kong Monetary Authority and the Bank of Thailand, to experiment with cross-border use of digital currencies.\nLast year, Swiss intensified efforts to issue a CBDC, which saw its apex bank partner with its Swiss stock exchange operator SIX Group.\nAt the time, the project was launched to explore how CBDC could be used to settle tokenized assets between market participants.\nCentral banks consider CBDC\nAs the use of banknotes in payment declined globally due to recent events, including the coronavirus (COVID-19) pandemic, countries are considering ways to enhance their payment systems from the obsolete traditional means to digital methods.\nThis need has prompted nations to embark on a series of research projects to study the possibility of issuing CBDC and its impact on their economies to remain relevant when the need arises.\nEarlier this month, the BIS, in collaboration with seven central banks, including the SNB, published a report outlining how banks should design CBDCs in order to align with existing policies.\nAs per the report, CBDCs should coexist with existing payment methods, support broader policy goals, and promote end-users’ innovation and efficiency.\nExclusive Offer: Signup on Bybit before Oct 31 and get a $60 bonus on your first 0.1 BTC/1000 USDT deposit to trade crypto.\nOriginal Article\nAuthor: Lele Jima", "pred_label": "__label__POS", "pred_score_pos": 0.9330809712409973}
{"content": "Private debt\nPrivate debt is the debt accumulated\nby individuals or private businesses. Private debt can take numerous forms; a personal loan, credit card, corporate bond or business loan for instance.\nPrivate debt comes with numerous pitfalls and risks for the applicant. When a loan is provided by family or friends, missed repayments can cause tension and even result in the end ofrelationship. Debt incurred with a credit provider may result in high levels of interest, charges for missed payments or demands for security.\nCredit providers may ask for\nsecurity over an asset or in the form of a guarantee in return for a secured loan. If security is given, the borrower can risk their home if they can't make repayment of their debts.\nThe risk of private debt doesn’t only lie with the debtor. The creditor risks non-repayment of funds or the need to issue lengthy and costly legal proceedings when they agree to make a loan. If a company goes into liquidation or a person enters bankruptcy, a creditor will lose all of the majority of their investment.\nPublic debt\nPublic debt, or national debt, is the sum of the financial obligations incurred\nby all government bodies of a county. This debt can be accumulated by the government directly or a government agency at any level.\nPublic debt can arise from a number of sources, for example government bonds create a debt owed by the government to a member of the public. Alternatively,\nSovereign Debt is accumulated when the government of a county borrows money from the government of another.\nThe public technically owns the debt. However, the debt will be viewed by the rest of the world as linked to the country as whole. The choice to create public debt is ultimately not that of its owner, and is entered into by a few but paid for by many.", "pred_label": "__label__POS", "pred_score_pos": 0.6717694997787476}
{"content": "The main objective of this guide is to inform readers clearly and graphically about the situation of a loved one affected by brain injury. The guide also provides specific guidelines on how to act so that families and/or carers can collaborate daily in their loved one’s neurorehabilitation treatment.\nThis guide does not seek to replace the work of our specialists. Instead, it acts as a reference for both professionals and families, helping them to discover how to begin living with a person with brain injury.", "pred_label": "__label__POS", "pred_score_pos": 0.8539304137229919}
{"content": "Secured programming is critical when developing server side systems today. Hacking and exploiting data is the “New Age Terror” and can lead to horrible results starting with stealing private data up to taking a whole system down (Banking services? Military? Health care?).\nSecurity must be provided in all layers of hardware and software since a tiny crack is enough to sink the whole ship…. Therefore, secured code means securing everything we develop, administer and configure.\nThis seminar explores the need, types of attacks and assumptions we must follow to keep our code secured.\nSoftware Developers, Managers, Architects and Project Managers that want to secure their systems and have a better understanding of the threats of today.", "pred_label": "__label__POS", "pred_score_pos": 0.668991208076477}
{"content": "A comparative in vitro antioxidant potential profile of extracts from different parts of Fagonia cretica Asian Pacific Journal of Tropical Medicine 2014, 7S1: S473-80\nOBJECTIVE: To evaluate antioxidant and radical scavenging activities of organic extracts from fruit, roots and aerial parts of Fagonia cretica.\nMETHODS: Shed dried and powdered plant parts were initially extracted in methanol and subsequently partitioned in n-hexane, chloroform, ethyl acetate and 1-butanol successively. Antioxidant and radical scavenging potential of the methanol extracts and the fractions of each part were evaluated using total phenolic contents (TPC) and total flavonoid contents (TFC), 2,2-diphenyl-1-picrylhydrazyl and 2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) radical cation radicals scavenging, reducing power (potassium ferricyanide-trichloroacetic acid system), ferric ion reducing antioxidant potential, lipid peroxidation inhibition activity (linoleic acid system) and total antioxidant activity (phosphomolybdate) assays.\nRESULTS: TPC and TFC values for methanol extracts and various fractions ranged from 0.23-4.30 mg/L gallic acid equivalents and from 30-545 mg/L rutin equivalents, respectively. Overall, methanol extracts and all the fractions of root and aerial parts showed higher TPC and TFC values. Methanol extracts and aqueous fractions of root and aerial parts and the n-butanol fraction of root showed lower EC50 values for 2,2-diphenyl-1-picrylhydrazyl scavenging than the other plant extracts. The 2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) radical scavenging, total antioxidant potential and ferric ion reducing antioxidant potential values confirmed the presence of potent antioxidant principles in the methanol extract of roots. In general, all the extracts/fractions and especially those of root showed high antioxidant and radical scavenging activities.\nCONCLUSIONS: The crude methanol extract of root can be explored further for in vivo studies. This study revealed the potent antioxidant potential of Fagonia cretica and its prospective efficacy against various reactive oxygen species-mediated diseases.", "pred_label": "__label__POS", "pred_score_pos": 0.5099120140075684}
{"content": "The aim of soil tillage is to maintain a favourable and stable soil structure, and to offer suitable conditions for crop installation and growth (ASIAT, 1989). This objective is reached by a reduction of soil disturbance and by no-till techniques, which limit the loss of soil fertility particularly in field cropping systems.\nHere we are interested in the influence of conservation tillage on plant nutrition, weed control and crop performance. These different factors and the evolution of soil properties are studied, among others, in a long term experiment comparing conventional tillage with three treatments without ploughing.", "pred_label": "__label__POS", "pred_score_pos": 0.5265563130378723}
{"content": "Abstract : Lactate is a key metabolite that is produced by every cell and oxidized by most of them, provided that they do contain mitochondria. Its metabolism is connected to energetic homeostasis and the cellular redox state. It is well recognized as an indicator of severe outcome in severely ill patients, however, it is not a detrimental factor per se. Conversely, some recent data tend even to indicate a beneficial effect in several metabolic disorders. Although the liver has long been recognized as a key organ in lactate homeostasis, the kidney also plays a major role as a gluconeogenic organ significantly involved in the glucose-lactate cycle. In acute renal failure, sodium lactate is widely used as a buffer in replacement fluids because the anion (lactate - ) is metabolized and the cation (Na + ) remains, leading to decreased water dissociation and proton concentration. The metabolic disorders related to acute renal failure or associated with it, such as liver failure, may affect lactate metabolism, and therefore they are often regarded as limiting factors for the use of lactate-containing fluids in such patients. By investigating endogenous lactate production in severe septic patients with acute renal failure, we found that an acute exogenous load of lactate did not affect the basal endogenous lactate production and metabolism. This indicates that exogenous lactate is well metabolized even in patients suffering from acute renal failure and severe sepsis with a compromised hemodynamic status.", "pred_label": "__label__POS", "pred_score_pos": 0.6051367521286011}
{"content": "Maine head-on collisions are typically some of the most devastating types of accidents because they tend to lead to serious injuries or death. Unlike other collisions, head-on collisions involve two cars that are traveling toward each other before the accident. In these accidents, the drivers and front passengers are often flung toward, and maybe through, the front windshield. According to the Insurance Information Institute, head-on collisions account for approximately 2 percent of motor vehicle accidents, but they lead to 10 percent of yearly accident-related deaths.\nFor example, recently, a Maine news report described a harrowing head-on collision involving a car and a pickup truck. An initial investigation revealed that a sedan heading east crossed into a center lane. The pickup truck driver was traveling westbound when the sedan slammed into his vehicle. The sedan driver was not wearing a seat belt and was ejected from his car. His female passenger was wearing a seat belt but died at the scene of the accident. The pickup truck passengers were wearing seat belts, but were transferred to a hospital for their injuries.\nLike the collision above, most head-on accidents occur when a motorist crosses to the wrong side of the road. Although these situations may occur because of poor road conditions, defective vehicles, and bad judgment, the majority occur because of driver impairment. The at-fault driver may be fatigued or driving under the influence of drugs or alcohol. In fact, the Centers for Disease Control cites drowsy driving as a leading cause of head-on collisions.\nIn situations where the parties survive the accident, they are usually still left with serious injuries. The most common head-on collision injuries include traumatic brain injuries, broken bones, burns, and even paralysis. After a head-on collision, establishing liability may be challenging because the impact often causes a chain reaction, and the parties end up in vastly different locations. An attorney can assist accident victims and their loved ones in establishing the responsible parties. Attorneys can work with an accident reconstructionist to determine the events that led up to the accident. Further, attorneys can consult with physicians and review medical records to determine the extent of injuries and potential future medical expenses. Finally, and most importantly, attorneys can present a claimant’s case in a compelling and effective manner to the judge or jury.\nHave You Been Injured in a Maine Car Accident?\nIf you or someone you know has been injured or killed in a Maine car accident, contact the dedicated attorneys at Peter Thompson & Associates. The attorneys at our law firm have extensive experience successfully advocating for Maine injury victims in all types of personal injury claims. We have helped countless clients obtain compensation from at-fault motorists, negligent government entities and companies, and insurance companies. Compensation in Maine accident cases often includes payments for medical expenses such as ambulance fees, hospital stays, and rehabilitation facility costs. Additionally, compensation may include payments for lost wages, pain and suffering, and emotional distress. Contact our office at 800-804-2004 to discuss your accident case with a knowledgeable attorney. Calling is free, and we will not bill you for our services unless we can help you obtain compensation for your injuries.", "pred_label": "__label__POS", "pred_score_pos": 0.6315526962280273}
{"content": "Answer\nThis condition is characterized by brief episodes of vertigo, disequilibrium, and nausea. It is usually found in children aged 2-6 years. The patient may have nystagmus within, but not between, the attacks. The child does not have hearing loss, tinnitus, or loss of consciousness. Symptoms usually last only a few minutes. These children often develop a more common form of migraine as they mature.\nBrain MRI can be performed to exclude posterior fossa abnormalities, especially if abnormalities in the neurologic examination are found between episodes.", "pred_label": "__label__POS", "pred_score_pos": 0.6484054923057556}
{"content": "Thanks to both\nadvances in technology and miniaturization of hair removal devices, hair removal at home is finally becoming accessible to individuals with depilator devices based on intense pulsed light or IPL technology. Advances in Technology\nSeveral permanent hair removal devices exist. They provide\nlong lasting depilation with professional results and are safe, painless and less expensive than beauty centers or medical offices.\nHowever, since these devices are using the\ntechnology of intense pulsed light or strobe light, derived from that used in medical offices and beauty salons, make sure you have read the corresponding IPL depilation page as well as the tips below.\nIs Permanent Hair Removal at Home the Right Treatment for me?\nAlso used in beauty centers, these new IPL hair removal devices are\nparticularly effective on dark hair and white skin. However, they are not so effective on white hair, red, light blond and dark skin but they remain acceptable. All areas of the body can be flashed such as legs, breast, chest, back, arms, underarms, hands, stomach, bikini, except the face. Are There Warnings for IPL Hair Removal Devices?\nTo ensure safe operation, these devices should\nnot be used on pregnant women, on varicose veins, scars, moles or tattoos. You should avoid sun exposure a few weeks before and after depilation sessions so your skin remains without unwanted long-lasting marks.\nIt is also important to know that\nbetween each hair removal session, the traditional hair removal techniques are prohibited; only the razor may be used. How Much do Home Permanent Hair Removal Devices Cost?\nVarious devices exist in a variety of prices ranging\nfrom $250 to $850 depending on the model and options such as built-in skin tone sensor, flash rate, time for recharging…etc.\nFor example, one of the most used devices\nfor both men and women is the FDA cleared and clinically proven Remington IPL6000 Hair Removal System.", "pred_label": "__label__POS", "pred_score_pos": 0.595308780670166}
{"content": "Editor’s Note: This blog post was contributed by Everyday Health.\nPsoriasis is an autoimmune, chronic condition, characterized by skin changes and other systemic manifestations. Aside from the treatment, and avoidance of trigger factors, such as stress, your doctor might recommend a change in your diet.\nA healthy diet is something anyone should consider, not only those who suffer from psoriasis. However, if you have been diagnosed with this condition, diet changes might help you keep the associated symptoms under control. Keep on reading and discover a few diet tips that might be helpful.", "pred_label": "__label__POS", "pred_score_pos": 0.984571635723114}
{"content": "Article Title Abstract\nJames Madison noted that \"[t]here are two methods of curing the mischiefs of [a] faction: the one, by removing its causes; the other, by controlling its effects.\" Campaign finance regulation, often spoken of as curing the mischiefs of special interest groups, has experienced a popular resurgence spawned by inquiries into extranational contributions in the 1996 presidential election and the 104th Congress' filibuster of the McCain-Feingold reform package. Since the Supreme Court's decision in the 1976 case Buckley v. Valeo, striking several parts of the Federal Election Campaign Act for infringing upon First Amendment-protected political expression, the efficacy of campaign finance reform laws has been significantly abrogated by the Buckley-articulated necessity that to survive, such laws must be narrowly tailored to serve compelling government interests. While the Buckley Court relied solely on the interest of corruption, it concurrently indicated the possibility that other \"ancillary\" interests could also bolster reform. Subsequent Court decisions have characterized corruption as the sole interest emerging from Buckley, and have maintained a nearly impregnable strict scrutiny in this context of political expression.\nDuring the past decade, several states have enacted more radical reforms, involving variable contribution limits or \"cap gaps,\" partial public financing and aggregated group contribution limits-all of which have struggled to survive First Amendment challenges in federal and state courts. Most recently, in November of 1996, the state of Maine passed by referendum its Clean Election Act, structuring a full public financing system for state gubernatorial and representative races. Several groups are now challenging these laws on First Amendment grounds.\nThis Note reexamines the question of compelling government interests for campaign finance reform in light of \"radical\" reforms in Kentucky, Minnesota, Missouri, and Wisconsin and unprecedented full public financing in Maine. It concludes that a broader interpretation of corruption, preservation of representative government, and equalizing access to the process could each or together qualify as compelling government interests to withstand First Amendment review. In particular, both a broad conception of corruption and the interest in preserving representative government could justify Maine's Clean Election Act. While the First Amendment requires a high level of review, other constitutional interests in tension with the freedom of expression could require a broader conception of the interests of the state.\nRecommended Citation\nMolly Peterson,\nReexamining Compelling Interests and Radical State Campaign Finance Reforms: So Goes the Nation,25 Hastings Const. L.Q. 421 (1998). Available at: https://repository.uchastings.edu/hastings_constitutional_law_quaterly/vol25/iss3/3", "pred_label": "__label__POS", "pred_score_pos": 0.9678928852081299}
{"content": "Overlooked Election Disinformation on Google is a Danger to our Democracy\nWe are less than a week away from Election Day with millions of voters having already cast their ballots, but election disinformation seeking to suppress voter turnout continues to spread across all major social media platforms. Congress has held multiple hearings including one this week with the “Big Tech” CEOs examining the role of social media platforms in disseminating disinformation. While much of Congress’ attention has focused on the problems Facebook and Twitter continue to have, election disinformation on Google has flown under the radar. Because Google is one of the few companies Americans find trustworthy to provide them with accurate information, users seeking voting information could be led to disinformation that discourages them from voting undermines the integrity of the election.\nGoogle owns a vast array of products and features that bad actors can exploit to steer users towards disinformation. Google’s search engine alone provides multiple vectors for disinformation. For example, the company’s search engine includes an autocomplete feature, which matches the characters that a user has typed into the search bar with previous searches that start with those characters. Google also utilizes a ‘related searches’ feature, which shows keywords or phrases at the bottom of every results page that other users who searched for the same term also requested. Google News is another potential source of misinformation during the election season. Outside of Google’s search tools, the company manages a vast digital advertising business where bad actors can place misleading ads about elections and voting while users view search results or watch YouTube videos.\nTo be clear, Google has acknowledged it has a disinformation problem and has implemented policies to limit the spread of election-related disinformation and misinformation. However, Common Cause uncovered numerous instances of election disinformation across Google’s products. For example, Google autocompleted searches for both “don’t v” and “why you shouldn’t v” with search terms dissuading people from voting. We found that some Google searches for “vote,” “how to vote,” and “voting” all directed users to related searches about online voting, such as “vote online,” “how to vote online,” and “online voting website.” After we notified Google, the company took down much of this content, finding it was in violation of existing civic integrity policies. Nevertheless, these examples highlight Google’s inconsistent enforcement of its policies. Like Facebook and Twitter, Google has significant resources and should not have to rely on civil society groups to monitor whether its policies are being enforced.\nIn addition to inconsistent enforcement — for example, we found an example where an issue-based ad by the GOP was properly disclosed but a nearly identical one was not (Google confirmed that they removed the non-disclosed ad after we alerted them to it) — Google’s efforts to stop the spread of election disinformation fall short due to significant gaps in its policies. For example, while Google has policies against ad misrepresentation, the platform allows advertisers to run ads promoting websites owned by anyone. This means advertisers can use Google search to place election ads that support or oppose candidates on websites intended to serve as a nonpartisan source for voting information. Further, Google has disclosure policies on political ads but defines those ads very narrowly. This means bad actors can target Google users with issue ads that contain misleading information about voting by mail without having to disclose who paid for them. Unless Google expands its definitions of harmful content when it comes to online voter suppression and advertisement disclosure policies, this content will continue to persist.\nBecause of Google’s significant reach and the high trust users have when searching for information, election disinformation on the platform poses significant risks to our democracy. While election disinformation remains a problem across all social media platforms, Google can no longer hide from the spotlight. The platform must do more to consistently enforce and expand its civic integrity policies to combat online voter suppression, and policymakers must do their part in holding Google accountable.", "pred_label": "__label__POS", "pred_score_pos": 0.7065931558609009}
{"content": "lewis park\nSituated at the foothills of the Dandenong Ranges in the City of Knox, Lewis Park is a significant piece of water infrastructure that doubles as a public open space for the community. Blind Creek, which runs through Lewis Park, was piped and channelised in the 1960s, reducing the biodiversity of the creek corridor and creating a disconnect between the water systems and surrounding residents.\nThis project aims to strengthen the user experience of and the community’s connection to the waterway system which runs through the municipality. This aim will be met by daylighting a total of 1650m of the concrete piped creekline, a long with several other initiatives. The broader site context consists of smaller reserves, parks, schools, residential land, light industry and a major commercial hub. This interface (as outlined in the Knox Central Structure Plan 2016) has provisions for future residential and commercial developments directly adjacent to the site. McGregor Coxall’s Lewis Park Masterplan published in February 2019 responds to this future condition and illustrates the future proposition for the Park. Driven by a collaborative dialogue between Knox City Council, Melbourne Water, the design team, the local community and close consideration of The Masterplan (McGregor Coxall, 2019), this project will enhance the existing amenity of the site by creating increased interaction with the waterway, enhanced connectivity and flexible open spaces.\nLocation\nLewis Park\nYear\n2020\nClient\nKnox City Council / Melbourne Water\nDesign Team\nJon Shinkfield, Brett Schreurs, Watkin McLennan, Allison Handan Chen", "pred_label": "__label__POS", "pred_score_pos": 0.9790241122245789}
{"content": "Babies as young as four months old process faces and scenes in a similar way to how adults do, shows a study published in Nature Communications.\nThe visual cortex in adults is divided into areas that process everything we see, such as faces, objects, and scenes. However, it is unclear whether these distinct areas arise as a result of exposure to the environment, or whether they are present from a young age. Ben Deen and colleagues provide evidence that indicates the visual cortex of the brain is already adult-like, in terms of structural organization, within a few months after birth.\nThe authors gather functional magnetic resonance imaging data from nine infants (aged four to six months) that were shown various images while lying in the scanner. Their results show that infants’ visual cortex responded similarly to adults’ presented with similar stimuli, indicating that infants as young as four months have areas in the visual cortex that process specific visual categories, such as faces and scenes. In a follow-up experiment, the authors demonstrate that these results are not due to any features of the stimuli (e.g. colour, brightness).\nThough the functional responses observed in infants’ brains were not as nuanced as those seen in adults, these results suggest that the large-scale organization of category preferences in visual cortex is already similar to that of adults after only four months of exposure to visual stimuli.\ndoi: 10.1038/ncomms13995\nResearch highlights\nNov 26\nNov 25\nZoology: Mineral armour discovered in insects Nature Communications\nNov 24\nNeuroscience: Social isolation evokes craving responses in the human brain Nature Neuroscience\nNov 20\nNov 18\nEcology: Migration associated with faster pace of life Nature Communications\nNov 17\nGene therapy: Concerns for the long-term safety of AAV gene therapy Nature Biotechnology", "pred_label": "__label__POS", "pred_score_pos": 0.6881920695304871}
{"content": "We are passionate about creating elegant and comfortable interior design, but we are equally committed to ensuring the process is rewarding and enjoyable for our clients.\nWe achieve this through a carefully-designed, step-by-step process that optimises the design and detailing stages, including any logistical or financial parts of the project. Through every stage of the process, we work with our clients and keep them fully informed of the plans and progress.\nOur interior design services are driven by our commitment to delivering exquisite, perfectly imperfect interiors for both residential and commercial projects, on-time and on-budget.\nOur starting point for every design project is to fully understand our client’s practical requirements and personal aspirations. The initial no-obligation meeting is designed to enable clients to easily and enjoyably share their ideas and personal style, the practical requirements of the project, and how they would like their new interior to enhance their lifestyle or working environment.\nThis meeting is best undertaken in the home or location of the refurbishment, so we can fully understand the space as it is and how it could be transformed. Alternatively, we are very happyto welcome clients at our studio in Chelsea.\nDuring this phase, we will also start to take into account logistical factors, such as budgets, timescales and planning requirements, along with any other practical considerations.\nFollowing the initial interior design consultation, we will present a proposal that outlines the brief as we understand it, as well as a clear initial project plan including estimated timelines, budgets, planning or logistical requirements, and our associated design fees.\nWe will also present a detailed description of the process, tailored to each client’s requirements. This provides an ideal opportunity for a client to raise any questions or concerns they may have about the process, as we are passionately committed to ensuring that clients are fully informed and comfortable with every stage of the project.\nOnce the proposal and detailed brief has been approved, we will present initial design concepts, which typically consist of creative and technical elements. Floorplans will be presented, showing ideas on space planning, structural changes, furniture layouts, bespoke joinery, lighting and audio/visual placement.\nA range of mood boards will bring the concepts to life through a combination of construction materials, colours, fabrics and ideas for the furniture, fixtures and accessories. As we specialise in working with residential and commercial buildings with an innate sense of character, we pay particular attention to how your interior will feel homely and inviting, when lots of new elements are introduced. During this phase, we present concept sketches and elevations. It is very much a collaborative process, so we welcome an open, relaxed discussion.\nDuring this phase, the approved design concepts are fully developed so that all of the necessary design detailing has been specified and ready to hand over to your contractors. We can recommend trusted partners or can work closely with your preferred suppliers on your behalf for the duration of the project.\nDuring this stage, we will draw up detailed architectural plans and designs for fitted joinery and custom-made furniture, and present you with all final finishes and specifications. This encompasses all of the furniture, fixtures and fittings, along with the work undertaken by contractors (such as builders, decorators, plumbers and curtain makers).\nFinally, should you required it, we can help oversee the team who will deliver the project to completion, should this be required. For larger projects we will work closely with an appointed project manager, who is responsible for the day-to-day logistics, quality control and long-term planning. From managing the tendering and procurement process to ensure maximum value and quality; to guaranteeing that the on- and off-site craftsmanship and trades are delivered to the required quality, budget and schedule; we can help ensure your new interior is delivered as smoothly as possible, with minimum hassle for you.\nA key part of creating the perfectly imperfect design aesthetic is ensuring that the interior styling is also considered. We would be delighted to help you dress your new scheme with all of the essential finishing touches.\nThis project diary – detailing my first big project in the UK – offers an insight into the interior design process, with all its flaws and imperfections. Having a design philosophy that celebrates imperfections, I think it’s especially fitting to share a ‘real-time’ record of what goes into creating a beautiful interior.\nBy getting into the day-to-day discoveries and decisions, shining a light on oversights and literal cracks and wonky floors – as well as on triumphs and delights – I hope to not only make the interior design process more transparent, but to reveal how imperfect aspects and unexpected challenges contribute to a stunning home full of character.\nSo here it is – a no-holds-barred view on the design process – I hope you enjoy the ride!\nPlease enter your details below if you’d like to receive relevant information from time to time.", "pred_label": "__label__POS", "pred_score_pos": 0.507988452911377}
{"content": "Abstract\nConversion of lignocellulosic substrates is limited by several factors, in terms of both the enzymes and the substrates. Better understanding of the hydrolysis mechanisms and the factors determining their performance is crucial for commercial lignocelluloses-based processes. Enzymes produced on various carbon sources (Solka Floc 200, lactose and steam-pre-treated corn stover) by\nTrichoderma reeseiRut C30 were characterised by their enzyme profile and hydrolytic performance. The results showed that there was a clear correlation between the secreted amount of xylanase and mannanase enzymes and that their production was induced by the presence of xylan in the carbon source. Co-secretion of α-arabinosidase and α-galactosidase was also observed. Secretion of β-glucosidase was found to be clearly dependent on the composition of the carbon source, and in the case of lactose, 2-fold higher specific activity was observed compared to Solka Floc and steam-pre-treated corn stover. Hydrolysis experiments showed a clear connection between glucan and xylan conversion and highlighted the importance of β-glucosidase and xylanase activities. When hydrolysis was performed using additional purified β-glucosidase and xylanase, the addition of β-glucosidase was found to significantly improve both the xylan and glucan conversion. Keywords Trichoderma reesei Rut C30 Cellulase fermentation Enzymatic hydrolysis Accessory enzymes Hemicellulases beta-Glucosidase", "pred_label": "__label__POS", "pred_score_pos": 0.9316099286079407}
{"content": "Genetic analysis of agronomic and quality traits in popcorn hybrids. Date2012 Author\nJele, Collinet Phumelele.\nMetadataShow full item record Abstract\nPopcorn is increasingly becoming popular as a snack and is consumed widely all over the world. It is a high value crop, with possible multiplier effects like income generation for the under-resourced communities in the second economy. Despite its popularity, developing countries are battling to meet the demand and rely on importing popcorn grain due to challenges which include poor agronomic traits and slow breeding progress. Most of the imported varieties are not adapted to stress-prone local environments, which are prevalent in tropical sub-Saharan Africa. The objective of the study was to evaluate newly developed hybrids and inbred lines for agronomic and popping quality traits with the possibility for commercialization in future. The study aimed at determining variability for popping ability in inbred lines and hybrids, grain yield and its secondary traits, the nature of gene action, relationships among agronomic and popping quality traits, effect of genotype x environment interaction on agronomic traits and popping method x genotype interaction effects. To determine popping ability, 128 inbred lines were evaluated at the University of KwaZulu-Natal, South Africa, in June 2011 using two popping methods, the microwave method and the hot-air method. The popping quality attributes measured were flake volume, popping fold, number of unpopped kernels, kernel size and quality score. Variability among inbred lines was significant (P<0.05) for all traits. Flake volume ranged from 63 cm3 to 850 cm3, popping fold ranged from 2.5 to 34 times the original volume. Kernel size had a significant positive correlation (r= 0.49) with the number of unpopped kernels. There was a significant strong and negative correlation between flake volume and the number of unpopped kernels (r= -0.62), indicating that either of the two traits would be effective for measuring popping ability. Experimental hybrids were then developed from 87 out of the possible 128 inbred lines. Only the inbred lines with sufficient seed were crossed to develop hybrids. Random crosses were generated at Makhathini Research Station during the winter season of 2011. Crosses were made at random among parents that managed to synchronize their flowering dates, resulting in 119 hybrids with sufficient seed for planting in trials. To determine agronomic superiority, the 119 experimental hybrids and the standard check P618 were evaluated at the Cedara Research Station and Ukulinga Research Farm in the Midlands of KwaZulu-Natal during the summer of 2011/2012. The experiments were laid out as 10 x 12 alpha lattice design, with two replications at each site. Standard cultural practices for maize were followed. The data were subjected to analysis of variance and line x tester analysis in Genstat and SAS statistical programmes. Results indicated that hybrids were significantly different for all agronomic traits. Means for grain yield ranged from 1.0 t/ha to 5.2 t/ ha. General combining ability effects were significant for all agronomic traits, suggesting that additive gene effects were governing these traits. Specific combining ability effects were significant for ear length, number of ears per plant and yield indicating, that non-additive gene effects were influential for these traits. Generally, agronomic traits were highly heritable. Grain yield showed significant and positive correlation with ear length, plant height, ear position, shelling percentage and number of ears per plant, indicating that these were the major yield-determining secondary traits which should be enhanced in popcorn. Although site main effects were highly significant for secondary traits, the hybrid x site interaction was not significant. The results therefore indicate that the hybrids were ranked similarly at both sites. The 119 experimental hybrids and the standard check P618 were evaluated for popping quality, using the microwave and the hot-air popping method. There was a significant variability observed among hybrids for popping quality traits. Flake volume across sites and across popping methods ranged from 734 cm3 to 1288 cm3. Popping fold ranged from 14.69 to 25.75 times the original volume. Additive gene action was more prominent than non-additive action for all popping quality traits. The SCA effects were significant for flake volume, popping fold and number of kernels per 10 g. All popping quality traits had high heritability, indicating that selection would be effective to improve popping. Flake volume was negatively correlated to quality score, indicating that popping expansion is reflected on the quality score and a significant negative correlation between flake volume and number of unpopped kernels. There was significant and strong positive correlation between kernel size and number of unpopped kernels. Hybrid x site interaction was only significant for quality score and kernel size. Hybrid x method interaction was not significant, indicating that popping ability was not dependent on the method. Inbred lines showed significant variation for popping quality and therefore have utility for hybrid development. Significant genotypic variation was also observed among hybrids for agronomic and popping quality traits. Additive gene action was predominantly responsible for both agronomic and popping quality traits. Both agronomic and popping quality traits were highly heritable and positive relationships were identified among traits. Overall, the study indicates opportunities for further breeding progress through selection.", "pred_label": "__label__POS", "pred_score_pos": 0.617833137512207}
{"content": "When you have a toothache or dental infection that is causing you pain, how can you find relief? In some cases, your dentist may prescribe an antibiotic. It may seem odd to take the same medicine for a toothache that you might take for a respiratory or ear infection. However, all infections‚ even those in the mouth, have something in common: They are caused by bacteria. That said, not all toothaches require antibiotics, so your dentist will decide when they are or aren’t needed.\nBacteria and Tooth Decay\nTo understand why your dentist might prescribe antibiotics for a toothache, you must first understand how bacteria contribute to tooth decay and toothaches. Without regular, twice-daily brushing with proper technique, the bacteria in your mouth can grow and turn the foods you eat into plaque and tartar that then gets deposited on your teeth. This promotes cavity formation and tooth decay.\nCommon Toothache Causes and Treatments\nWhen bacteria start to break down your tooth structure it can form a cavity that can either be fixed by your dentist with a simple filling or a crown. But if the cavity is not stopped early enough the decay can continue to grow and eventually reach the center of the tooth where the nerves are. Once the nerves become affected by the decay this can cause immense amounts of pain, and lead to an infection.\nWhen a tooth infection reaches the nerve of the tooth, it may require a root canal and a protective cover to seal bacteria out of the tooth. Additionally, if a tooth is so broken down by a cavity that it can’t be repaired, the dentist may need to extract the tooth.\nWhen Does a Toothache Require Antibiotics?\nWhen the dental infection is severe or impacts the gum around an erupting tooth, your dentist may recommend antibiotics. For instance, pericoronitis is an infection in the gum tissue that can develop around impacted wisdom teeth. Patients with this condition may be given antibiotics as part of their treatment.\nAdditionally, if your dentist notices signs of a dental abscess‚ a tooth infection that can develop from an untreated cavity, they may recommend antibiotics.\nTaking Antibiotics for Oral Infections\nFor dental infections, dentists will often prescribe penicillin or amoxicillin. Clindamycin is also a commonly prescribed alternative for those allergic to penicillin. Your dentist will be sure to identify the right dose and duration of medication for your particular situation. Because over-prescription of antibiotics can sometimes lead to more resistant strains of bacteria, your dentist will also take antibiotic resistance into consideration when they prescribe your dose.\nIt’s important to take the full course of pills exactly as your dentist prescribes for the best outcome. Just remember, even if the pain resolves, you’ll likely still need further treatment to fully restore your tooth.\nToothache Prevention\nThere are many ways to help prevent toothaches. Following these steps can help you reduce your risk of cavities or a toothache:\nLimit your frequency and intake of sugary foods and drinks. Brush your teeth with fluoride toothpaste twice daily to decrease the sugar and bacteria accumulation on your teeth. Floss between your teeth, once a day, to prevent cavities from forming where your teeth touch. Maintain regular checkup appointments so that your dentist can continue monitoring your risk of cavity formation.\nYou can take steps to help prevent cavities and tooth infections. However, if you already have one, know that your dentist has your best interests in mind if they prescribe you antibiotics for a toothache.", "pred_label": "__label__POS", "pred_score_pos": 0.7293844223022461}
{"content": "We hope that after it's over, governments will invest more heavily in medical technology, namely in preventive vaccinology such as VPRE, that would spare the shortcomings we are living now. This is the future we envision VPRE to flourish in: where preventive vaccines informed by extensive sequencing measures allow for protection against viruses that haven't even arisen yet.\nAs we upgrade our tool, we plan to generalize it to all viruses, allowing us to implement the same predictions on any virus that either uses humans and hosts or currently resides in animals but could potentially harm humans. Envision a world in which we diligently monitor virus populations in wildlife, livestock, and people. We could predict when, where, and which viruses will cause an outbreak,\nand have a vaccine ready before it happens.\nWhat if this world was within our reach? As we grow aware of the myriad ways in which our actions impact Earth and everyone on this planet, it is time for humanity to unite with a collective goal: to use our innovation to influence the world positively with our actions. A new world is emerging.\nWe have worked with various organizations, experts, and locals in order to best formulate the scope of our project, as well as the risks and concerns.\nThough we would like it to be so, we recognize that our vision could be compromised in people and countries of different socioeconomic status, specifically in producing and distributing vaccines, and monitoring markets and livestock diligently. Developing countries often don't have the allocated funds necessary to support facilities such as a vaccinology centre, nor the educational resources for accessing an online learning tool like VPRE.\nHowever, we have considered possible shortcomings that would arise in these communities. The cost of genome sequencing has been at a steep downfall since its creation, making sequencing of infected livestock and people more accessible to poorer communities. Additionally, the geographical spread of places where genomes have been sequenced has been continuously growing with projects such as the 1000 Genomes Project, which collected human genomes from 26 countries to analyze genomic variability. These initiatives indicate that the trend will continue in upcoming years and hence would support our futuristic vision in the implementation of VPRE.", "pred_label": "__label__POS", "pred_score_pos": 0.5452035665512085}
{"content": "Call for Submissions: Feminist Africa 2021\nMonday, April 20, 2020 12:00 AM Gender and Sexuality in African Futurism Volume 3, Issue 1\nGuest Editor: Jacqueline-Bethel Mougoué\nHow does the African Futurist genre (re)imagine gender norms, sexual identities, and issues of feminism on the continent? This special issue will explore questions of gender and sexuality in “African Futurism,” a term that has gained currency since Nigerian-American novelist Nnedi Okorafor used it in a November 2018 Twitter post. Our contributors draw from African sources to explore how African Futurism has become a cultural genre exploring varied ideas about gender and sexuality in African cultures, as these are expressed and performed in ways that traverse and transcend time and space.\nContributors to FA Vol 3 Issue 1 ask what “African Futurism” comprises, and explore its relationship to the older term “Afrofuturism”, a cultural movement that emphasized philosophical, technological and aesthetic features of Black cultural expression and performance in the African diaspora. Well-known explorers of Afrofuturism include scholars (Mark Dery, Ytasha Womack, and Reynaldo Anderson), novelists and short story writers (Octavia Butler, Samuel R. Delaney and Nalo Hopkinson) and singers (Sun Ra and Janelle Monáe). While Western Afrofuturists acknowledge how cultural exchange across the Atlantic influenced Afrofuturism, continental Africans have suggested that Afrofuturism does not adequately address the continent and its peoples, fails to reflect contemporary and indigenous cultures, experiences, and histories, thereby failing to distinguish continental Africa’s contribution to the futurist imaginary. For example, South African writer Mohale Mashigo argued in\nHowever, both African Futurism and Afrofuturism depict profoundly patriarchal African cultures. As African women have become the main protagonists of African Futuristic works, we ask whether the emergence of contemporary African Futurism has greater transformative potential for African women than Afrofuturism as continental authors claim?\nNo events", "pred_label": "__label__POS", "pred_score_pos": 0.8546120524406433}
{"content": "Autism affects nearly one in every 59 children. It is a life long developmental brain disorder with a variable outcome ranging from severe, sometimes violent, disruptive and destructive behaviors, serious communication deficits and odd, repetitive, restrictive behaviors. There is no cure. It is predominantly a genetic disorder but there remain many unknowns. We do not yet understand why autism occurs in certain families or why these individuals have such complicated behavioral or mental health conditions.", "pred_label": "__label__POS", "pred_score_pos": 0.9991413950920105}
{"content": "It aims to bring the world online.\nMark Zuckerberg, the founder and CEO of Facebook, has launched a new project which aims at making internet access available to the next 5 billion people.\nCalled Internet.org, the partnership will work to develop joint projects, share knowledge, and mobilise industry and governments to bring the world online.\nFounding members from Ericsson, MediaTek, Nokia, Opera, Qualcomm and Samsung are also all involved.\n2.7bn people currently have access to the internet, according to Facebook. The goal od Internet.org is to connect the remaining two-thirds of the world’s population to bring everyone the same opportunities that the connected third has today,\n\"There are huge barriers in developing countries to connecting and joining the knowledge economy,\" said Zuckerberg, who has also published a white paper entitled ‘Is Connectivity a Human Right?’.\n\"Internet.org brings together a global partnership that will work to overcome these challenges, including making internet access available to those who cannot currently afford it.\"\nInternet.org will focus on three key challenges in developing countries: making access affordable, using data more efficiently and helping businesses drive access.\nThe founding companies have a long history of working closely with mobile operators and expect them to play leading roles within the initiative, which over time will also include NGOs, academics and experts.\nInternet.org is inspired by the Open Compute Project, an open source initiative launched by Facebook in 2011 to help build cheaper, more efficient computing infrastructure.", "pred_label": "__label__POS", "pred_score_pos": 0.921588122844696}
{"content": "A question of trust – Mitigating customer risk in digital financial services\nThis paper synthesizes four studies examining customer experience in Bangladesh, Colombia, Philippines, and Uganda. It highlights that system downtime, agent illiquidity, agents charging unauthorized fees, the fear of sending money to the wrong number and unresponsive customer care centers all eat into the credibility of digital finance offerings.", "pred_label": "__label__POS", "pred_score_pos": 0.9721179604530334}
{"content": "Coping measures for “measurement” in the time of COVID-19\nCOVID-19 has seen governments across the globe walk a tightrope as they scramble to contain the spread of the disease while keeping the economy stable. In this unprecedented situation, ground-level data for evidence-based decision-making assumes critical significance. This blog looks at five key lessons from MSC’s research on COVID-19.", "pred_label": "__label__POS", "pred_score_pos": 0.9428396821022034}
{"content": "This is a challenging era for commissioners of health and social care services; with many being tasked with delivering additional and better services, often with reduced funding.\nNRS Healthcare supports commissioners in overcoming these challenges whilst achieving their strategic objectives. These could include increasing safe hospital discharge rates or helping health and social care professionals to increase their efficiency and effectiveness.We do this by using our expertise and in-depth understanding of the health and social care environment to identify the right solutions, tailored exactly to individual needs.\nWe take a holistic approach and ensure our work integrates with other support provided to those in need, including unpaid carers and family members.\nIf you are an employee of NRS Healthcare and you wish to contact the People Department about an employment matter, please email HR@nrs-uk.co.uk this will ensure your enquiry is dealt with promptly and confidentially.", "pred_label": "__label__POS", "pred_score_pos": 0.9977731704711914}
{"content": "Tenants should take professional advice before renting out their homes to short-term paying guests via Airbnb, Booking.com or other internet booking sites. In a case on point, a couple who failed to take that sensible step placed themselves in jeopardy by breaching the terms of their lease.\nThe couple held their flat under a 125-year lease. In common with a great many such properties, the lease contained a covenant that forbade the flat's use for any purpose other than as a private dwelling house for occupation by one family at any one time. After they advertised the property for short-term lets on internet booking sites, their landlord launched proceedings.\nIn rejecting the landlord's complaint, the First-tier Tribunal (FTT) noted that there had been no complaints of nuisance or antisocial behaviour by the couple's guests. After relocating for work reasons, the couple had rented out the property as a temporary expedient prior to its planned sale. The FTT also noted that their lease permitted them to grant assured shorthold subtenancies of the flat, for up to six months, without obtaining the landlord's consent.\nIn upholding the landlord's appeal against that ruling, however, the Upper Tribunal (UT) noted that the use of a residential property for short-term occupation by a succession of paying guests has always been treated as a breach of a covenant requiring its use only as a private residence or dwelling house. The couple's entitlement to enter into subtenancies of short duration did not imply that the property could be used by a succession of unconnected strangers who generally only stayed for a weekend.\nOn a true interpretation of the covenant, short-term letting of the flat to persons who did not use it as their only or principal home would amount to a breach of the lease. Given the requirement that the flat be occupied by one family, the couple were also arguably prohibited from taking in a lodger. The landlord was granted a formal declaration that the couple had breached the covenant.", "pred_label": "__label__POS", "pred_score_pos": 0.8832740783691406}
{"content": "In recent months, organizations around the globe have been forced to quickly adapt to significant change on-the-fly. Nearly every industry has been impacted, but manufacturing, service, and retail have seen some of the most severe disruptions.\nJoin us on\nSeptember 3, 2020, 10 a.m. CET for a webcast with ABI Research to explore how businesses can solve their most pressing challenges by equipping their frontline employees with augmented reality. Discover why businesses are increasingly leveraging AR use cases such as real-time remote assistance, virtual training, and rapid knowledge capture to:", "pred_label": "__label__POS", "pred_score_pos": 0.9997482299804688}
{"content": "Notice 2018-38 (the Notice), released by the IRS on April 16, provides guidance on the application of Section 15(a) in determining federal income tax (including the alternative minimum tax or AMT) of a corporation for a tax year that begins before January 1, 2018, and ends after December 31, 2017. The Notice provides fiscal-year taxpayers with computational examples for the computation of both federal income tax and AMT.\nCorporations with tax years beginning before January 1, 2018, and ending after December 31, 2017 should consider how Section 15(a) will affect the computation of federal income tax and the AMT. The Notice provides numerical examples to illustrate how these computations are performed.", "pred_label": "__label__POS", "pred_score_pos": 0.5393276214599609}
{"content": "The World Customs Organization’s Technical Committee on Customs Valuation (the Committee) issued Case Study 14.2 to address whether certain transfer pricing documentation was sufficient to support the arm’s length nature of a related party pricing transaction. While the Committee found that the companies included in the transfer pricing report were suitably comparable, their gross margins were significantly lower than that achieved by the importer. Also, the Committee noted that the the importer did not make a transfer pricing adjustment to address the inconsistency. Accordingly, the Committee determined that the relationship between the parties had influenced the price. As a result, the Committee concluded that declared value had not been settled in a manner consistent with the pricing practices of the industry, and that alternative valuation methods must be used.\nCase Study 14.2 is a reminder to importers that without coordination, transfer pricing documentation and the attendant decisions regarding transfer prices may also be used by customs authorities to undercut the arm’s length nature of related party pricing.\nThe importer’s decision to forgo a transfer pricing adjustment to bring its results in line with the interquartile range identified in the transfer pricing documentation led the Committee to conclude that the prices were not settled in a manner consistent with normal pricing practices of the industry. Thus, the related party pricing was not arm’s length, and requires an alternative method of customs valuation. This result potentially leaves the local importer in a worst case scenario. From the income tax perspective, the high gross margin will be subject to taxation. From the customs perspective the imported merchandise likely would be subject to the increased administrative burden of applying an alternative valuation method plus a likely adverse duty impact based on such alternative customs values. Close cross-functional coordination of tax and customs considerations can help importers mitigate their risk of being challenged by customs and tax authorities.", "pred_label": "__label__POS", "pred_score_pos": 0.9549669027328491}
{"content": "Ibotta, a Denver, Colo.-based mobile shopping app, released findings of a consumer shopping study that found a significant increase in grocery shopping among fathers.\nThe study, which analyzed the shopping behavior of more than 90,000 dads since 2013, revealed that Millennial dads are spending the overall most time in the grocery aisles, increasing the number of grocery purchases by 62% since 2013, while the younger fathers in this age group (ages 18-24) are purchasing 25% more groceries than dads in older generations.\nThe study also shows that men are making more trips to the grocery store each month – up nearly 5% since 2013 – and that their overall shopping in general was up more than 10% in the last three years. And, while the number of grocery trips has slightly increased since 2013 among moms, the share of groceries purchased by Millennium moms decreased by 2.4% during the same timespan.\n\"The data suggests that Millennial dads are playing an increasingly bigger role at home, taking on more domestic responsibilities such as household shopping,\" says Bijal Shah, vice president of analytics and data products. \"This marks a generational shift from older fathers who embraced traditional gender roles, and is bolstered by mobile-enabled commerce and younger dads' savviness with smartphones and shopping apps.\"", "pred_label": "__label__POS", "pred_score_pos": 0.5716718435287476}
{"content": "Impact of Acid Rain on Human Health Corrosive downpour looks, feels, and tastes simply like clean downpour. The mischief to individuals from corrosive downpour isn't immediate. Strolling in corrosive downpour, or notwithstanding swimming in a corrosive lake, is not any more perilous than strolling or swimming in clean water. The air contamination that causes corrosive downpour is all the more harming to human wellbeing. Sulfur dioxide and nitrogen oxides, the real wellsprings of corrosive downpour, can bother or even harm our lungs. The toxins that reason corrosive downpour can likewise decrease perceivability, constraining how far into the separation we can see. The essential contaminations related with corrosive downpour and poor perceivability are human-made sulfur dioxide outflows. These discharges structure little sulfate particles, or mist concentrates, in the air. These mist concentrates diminish perceivability by dispersing light. Sulfate pressurized canned products are the primary driver of poor perceivability in the eastern United States.\nNitrogen oxide discharges are additionally connected with the corrosive downpour issue Air contamination like sulfur dioxide and nitrogen oxides can cause respiratory sicknesses, or can exacerbate these illnesses. Respiratory maladies like asthma or ceaseless bronchitis make it difficult for individuals to relax. The contamination that causes corrosive downpour can likewise make little particles. At the point when these particles get into individuals' lungs, they can cause medical issues, or can aggravate existing medical issues. Likewise, nitrogen oxides cause ground-level ozone. This ground-level ozone causes respiratory issues, similar to pneumonia and bronchitis, and can even reason perpetual lung harm.\nThe wellbeing impacts that individuals need to stress over are not brought about by the corrosive downpour, yet are caused when individuals take in these modest particles or ozone. Swimming in an acidic lake or strolling in an acidic puddle is not any more hurtful to individuals than swimming or strolling in clean water.The last convergence of acids (for the most part sulfuric corrosive, H2SO4 and nitric/nitrous corrosive, HNO3/HNO2) in precipition (causticity) is reliant on emanations of SO2 and NOx from sources, climate conditions andother synthetic substances present in the atmoshpere. The development of sulfuric and nitric/nitrous corrosive in the environment is a mind boggling procedure including a few concoction responses including both arrangement and gas stage responses.\nStrolling in corrosive downpour, or notwithstanding swimming in a lake influenced by corrosive downpour, is not any more perilous to people than strolling in ordinary downpour or swimming in non-acidic lakes.\nNotwithstanding, when the poisons that reason corrosive downpour — SO2 and NOX, just as sulfate and nitrate particles—are noticeable all around, they can be destructive to people. SO2 and NOX respond in the climate to shape fine sulfate and nitrate particles that individuals can breathe in into their lungs. Numerous logical examinations have demonstrated a connection between these particles and consequences for heart work, for example, heart assaults bringing about death for individuals with expanded coronary illness hazard, and impacts on lung work, for example, breathing troubles for individuals with asthma.\nBy bringing down SO2 and NOx outflows from power age, the Acid Rain Program will lessen the degrees of fine sulfate and nitrate particles thus decrease the frequency and the seriousness of these medical issues.\nAt the point when completely actualized continuously 2010, the general medical advantages of the Acid Rain Program are assessed to be esteemed at $50 billion yearly, because of diminished mortality, clinic affirmations, and crisis room visits. Diminishes in nitrous oxide outflows are additionally expected to beneficially affect human wellbeing by lessening the nitrogen oxides accessible to respond with unstable natural mixes and structure ozone. Ozone impacts on human wellbeing incorporate various dismalness and mortality dangers related with lung aggravation, including asthma and emphysema.", "pred_label": "__label__POS", "pred_score_pos": 0.593917727470398}
{"content": "As the COVID-19 pandemic continues to unfold, we have seen many changes to daily life and work. The past few months brought school and business closures along with a record number of unemployment claims. With the unemployment rate continuing upward, states may need to re-assess the needs of individuals without employment and determine how to help them reenter the workforce into good jobs as part of economic recovery.\nA recent Strada Education Network survey found that 35% of respondents who lost hours or employment identified needing more skills in their current field to get a similar job, while another 34% mentioned needing more skills to transition to a new career field. As these statistics continue to fluctuate, states can begin evaluating their economic needs and how best to connect individuals to the education and training needed for upskilling and reskilling.\nOne specific data point from the April 15 survey highlights a mismatch between what people want and what institutions are offering: 59% of respondents prefer non-degree programs to increase their skills base. (Specifically, 26% of those who indicated they would pursue a non-degree program stated they would pursue a certificate or license.) Further, the May 6 update found that 36% of respondents indicated they would seek out a different field of work if they lost their job, which could speak to the increased interest in non-degree credentials. Typically, these programs can be quicker to complete and may have direct pathways into the workforce. Ensuring quality and providing clear pathways into careers are important aspects to consider in non-degree credentials.\nGenerally speaking, quality non-degree credentials are certificates, industry certifications, occupational licenses or apprenticeship certificates that provide value to an individual and business. For a worker, quality can be indicated by their ability, with the credential, to access a good job with sustaining wages and growth potential. Whereas for businesses, quality could mean that a credential is a clear indication of specific skills and training. The two perceptions of quality are not mutually exclusive and capturing them both are key considerations within a state’s process to identify and evaluate non-degree credentials.\nCreating Quality and Aligned Non-Degree Credential Pathways\nState policymakers can take steps to ensure the quality of non-degree credentials by establishing processes and criteria to evaluate the credentials and ensure they are connected to career paths in high-demand fields, as highlighted in the work from Education Strategy Group. To inform and create quality, non-degree pathways, states have resources to inform and guide the process, specifically data and established groups of workforce stakeholders.\nFor example,\nAlabama established a committee within its workforce development council to bring industry and other experts together to examine and evaluate specific credentials. The state uses a set of data and criteria to determine if a credential should be included on the state’s Compendium of Valuable Credentials.\nSimilarly,\nNew Jersey’s Department of Labor and Workforce Development has established a list of industry-valued credentials. The list was first established with employer input in 2018 and is reevaluated quarterly. The reevaluation of the credential list is done by senior staff from the department, plus New Jersey’s local One-Stop Career Centers and Workforce Development Boards, the state employment and training commission, department of education and secretary of higher education. As an indicator of quality to individuals seeking credentials, the department has an up-to-date public resource that details the credentials of value and the issuing agency.\nWhile employment and economic conditions will continue to shift, states have an opportunity to support individuals in upskilling and reskilling as part of their economic recovery. By providing individuals with clear indications of what credentials are valued and of quality, those looking to reskill or upskill can select paths that support them in their future jobs. Creating quality, non-degree credential pathways is one approach to meeting both individuals’ and businesses’ needs in an evolving economy.", "pred_label": "__label__POS", "pred_score_pos": 0.579218864440918}
{"content": "SUMMARY\nThe census is a once-in-a-decade event that affects the distribution of billions of federal funding each year on infrastructure and services like hospitals, schools, senior centers and public works projects based on national responses. With so much at stake, the federal government allocated funding for a national advertising campaign to educate residents about the impact of the 2010 census.\nThe team analyzed the situational factors surrounding the last two censuses in 1990 and 2000, as well as the response rates (61 and 69 percent, respectively). They also conducted a landscape analysis and retrieved data from the Nevada State Demographer’s Office and the American Community Survey from 2007 and 2008. What the team realized immediately was that Nevadans faced many different factors that previously did not exist, such as economic hardship and the highest foreclosure rate in that nation.\nPLANNING\nThe Ferraro Group met with the client, Nevada Secretary of State (SoS) Ross Miller; team members national PR firm Weber Shandwick, advertising firm Sawyer Miller and Hispanic marketing firm The Axis Agency; and other census partners including Strategic Solutions, contracted by the Southern Nevada Regional Planning Coalition, Nevada Demographer Jeff Hardcastle and U.S. Census Bureau Liaison David Byerman for a six-hour strategic planning session to identify objectives, audiences and challenges. The team identified a timeline of major census events and organized our PR & ad campaign to support these scheduled events and ensure the widest amount of media coverage for maximum impact.\nA key strategy toward achieving these goals was to communicate Nevada-specific reasons for participating – what it means to residents of\nour state to mail back their census forms. The campaign included working with local trusted partners to reach residents with messages that are relevant locally and culturally. It aimed to promote all Nevadans 18+ statewide to participate in the 2010 Census, with particular focus on hard-to-count populations including: minority groups, people who are temporarily displaced due to the foreclosure market and rural communities. IMPLEMENTATION Earned Media – Much of the support during the campaign came in the form of proactive and reactive media relations. This included developing and distributing press releases and advisories, coordinating media interviews for the SoS, drafting press kits and providing on-site support at major campaign events. -Campaign Kick-off – Beginning with a coordinated northern/southern Nevada campaign rollout on January 21 at the Boys and Girls Club in Reno and Three-Square in Las Vegas, TFG worked closely with the SoS office and local Complete Count Committees to organize press events focused on the importance of census participation to local community service groups and families they serve. -Ad Campaign Launch Press Conference – TFG organized a press conference unveiling the campaign’s creative component, including outdoor advertisements, on March 3, 2010. For this event, TFG developed electronic press kits that included a detailed press release and copies of all creative elements of the campaign. – National Census Day Event – TFG organized a two-day press event from March 31-April 1, 2010 in recognition of National Census Day. The two main goals of the event were to 1) continue encouraging people to fill out and send in their census forms, and 2) focus the statewide census participation message in hard to count communities in Washoe and Clark Counties. Social Media and Digital Outreach – TFG worked with the SoS office to develop an official microsite that served as a one-stop information hub for the 2010 Census in Nevada. Through TFG’s assistance, the microsite provided timely information on the campaign, including the distribution of press releases, resource toolkits for media and our Trusted Voices partners, videos produced by local CCCs and the statewide campaign, and key information from the U.S. Census Bureau. TFG also engaged Nevadans through a Nevada Census 2010 fan page on Facebook and a Nevada Census 2010 YouTube page. Hispanic Outreach – Each of the campaign’s Hispanic media partners [Telemundo (TV – Las Vegas), Entravision (Univision TV – Las Vegas), Entravision Radio (Reno) and Univision Radio (Las Vegas)] recorded and distributed co-branded Spanish-language PSAs that used our messaging and their most recognized talent to promote awareness of the census. RESULTS\nReports from local census officials noted that residents returned the 2010 census forms faster than they did in 2000. Nevada was one of the 11 states that matched the 2000 mail-in response rate. Nevada’s response to the 2010 census also qualified the state to have a fourth Congressional seat in the U.S. House of Representatives.\nThe Southern Nevada chapter of the Public Relations Society of America recognized the Nevada Census 2010 campaign in multiple categories during its annual Pinnacle Awards, which recognizes the best public relations programs, tools and professionals in southern Nevada, northern Arizona and southern Utah. An out-of-market judge commented that the Nevada Census 2010 campaign was “outstanding.”", "pred_label": "__label__POS", "pred_score_pos": 0.6064621210098267}
{"content": "Dwelling approvals on the rise\nTHE total number of dwellings approved in Australia rose 7.4% in seasonally adjusted terms in March.\nFigures released by the Australian Bureau of Statistics on Monday revealed the rise, which came after an 8.85% fall in February.\nNew South Wales led all states with a 49.3% rise in dwelling approvals in March, followed by Western Australia (11.1%) and South Australia (4.2%). Queensland suffered a sharp decline in dwelling approvals (-8.7%), along with Tasmania (-6.7%), and Victoria (-5.0%).\nApprovals for private sector houses rose 3.9% in seasonally adjusted terms in March, with rises in South Australia (16.3%), Western Australia (14.5%), New South Wales (3.5%) and Queensland (1.8%). Victoria fell (-1.0%).\nThe value of total building approved decreased 8.9% in March, following a decrease of 31.7% in February.\nThe value of residential building rose 1.3% while non-residential building fell 23.4%.", "pred_label": "__label__POS", "pred_score_pos": 0.7669654488563538}
{"content": "Avoid the Goose! Paramedic Identification of Esophageal Intubation by Ultrasound.Prehosp Disaster Med. 2018 Aug; 33(4):406-410.PD OBJECTIVES\nRapid identification of esophageal intubations is critical to avoid patient morbidity and mortality. Continuous waveform capnography remains the gold standard for endotracheal tube (ETT) confirmation, but it has limitations. Point-of-care ultrasound (POCUS) may be a useful alternative for confirming ETT placement. The objective of this study was to determine the accuracy of paramedic-performed POCUS identification of esophageal intubations with and without ETT manipulation.\nMETHODS\nA prospective, observational study using a cadaver model was conducted. Local paramedics were recruited as subjects and each completed a survey of their demographics, employment history, intubation experience, and prior POCUS training. Subjects participated in a didactic session in which they learned POCUS identification of ETT location. During each study session, investigators randomly placed an ETT in either the trachea or esophagus of four cadavers, confirmed with direct laryngoscopy. Subjects then attempted to determine position using POCUS both without and with manipulation of the ETT. Manipulation of the tube was performed by twisting the tube. Descriptive statistics and logistic regression were used to assess the results and the effects of previous paramedic experience.\nRESULTS\nDuring 12 study sessions, from March 2014 through December 2015, 57 subjects participated, evaluating a total of 228 intubations: 113 tracheal and 115 esophageal. Subjects were 84.0% male, mean age of 39 years (range: 22 - 62 years), with median experience of seven years (range: 0.6 - 39 years). Paramedics correctly identified ETT location in 158 (69.3%) cases without and 194 (85.1%) with ETT manipulation. The sensitivity and specificity of identifying esophageal location without ETT manipulation increased from 52.2% (95% confidence interval [CI], 43.0-61.0) and 86.7% (95% CI, 81.0-93.0) to 87.0% (95% CI, 81.0-93.0) and 83.2% (95% CI, 0.76-0.90) after manipulation (P<.0001), without affecting specificity (P=.45). Subjects correctly identified 41 previously incorrectly identified esophageal intubations. Paramedic experience, previous intubations, and POCUS experience did not correlate with ability to identify tube location.\nCONCLUSION\nParamedics can accurately identify esophageal intubations with POCUS, and manipulation improves identification. Further studies of paramedic use of dynamic POCUS to identify inadvertent esophageal intubations are needed. LemaPC, O'BrienM, WilsonJ, St. JamesE, LindstromH, DeAngelisJ, CaldwellJ, MayP, ClemencyB. Avoid the goose! Paramedic identification of esophageal intubation by ultrasound. Prehosp Disaster Med. 2018;33(4):406-410.\nMeSH Pub Type(s) Language PubMed ID Citation Prehospital and Disaster Medicine,vol. 33, no. 4, 2018, pp. 406-410. Prehosp Disaster Med. 2018;33(4):406-410. Prehospital and Disaster Medicine, 33(4), 406-410. https://doi.org/10.1017/S1049023X18000651 Prehosp Disaster Med.2018;33(4):406-410. PubMed PMID: 30129915.", "pred_label": "__label__POS", "pred_score_pos": 0.5013638734817505}
{"content": "In temporarily replacing regular Employment Insurance benefits, the new Canada Emergency Response Benefit has provided needed support to millions, in a short amount of time.\nHowever, the CERB has a glaring loophole that is short-changing workers from receiving additional income assistance from their employers.\nHundreds of thousands of workers in Canada have access to Supplemental Unemployment Benefit (SUB) payments when they are on layoff. These special, employer-paid benefit “top-ups” can provide hundreds of dollars, per week, to offset a worker’s loss of income.\nUnlike regular EI, the CERB rules deny workers these SUB payments that many have won at the bargaining table.", "pred_label": "__label__POS", "pred_score_pos": 0.9425205588340759}
{"content": "California’s public employee unions were handed a serious blow in a Supreme Court ruling Wednesday that forbids them from collecting fees from workers who benefit from their representation but do not want to join them.\nIn a 5 to 4 ruling, the court determined that public sector unions’ so-called “fair share” fees violate “the free speech rights of nonmembers by compelling them to subsidize private speech on matters of substantial public concern.”\nThe decision in Janus vs. AFSCME effectively makes California a “right to work” state, ending a 41-year precedent that allowed public sector unions to levy these fees on workers who don’t belong to labor organizations.\nTo unions, the fees ensured that employees don’t get a “free ride” by gaining raises and representation in workplace disputes without paying for those services.\nBut to critics inside and outside labor groups, the fees trampled the First Amendment rights of workers who believed the charges subsidized inherently political organizations that they opposed.", "pred_label": "__label__POS", "pred_score_pos": 0.759269654750824}
{"content": "Which is more likely to catch a reader’s attention: a pop science article referring to “human cortical spheroids” or “brain balls”? Each has its advantages, but also its drawbacks. Communication of science requires reader-friendly translation of jargon-filled, complex ideas, but it’s crucial that this is done accurately and without misinformed hype. For Stanford researcher Dr. Sergiu Pasca, this challenge isRead more", "pred_label": "__label__POS", "pred_score_pos": 0.9962966442108154}
{"content": "This person feels good about themselves when they are able to work with autonomy. This person puts a lot of faith in their own conclusions…they trust their own answer. This person is the most successful when they can work with a lot of autonomy. This person is able to draw from their past and what they know to make their decisions for the present. This person exudes confidence in what they know and will act on what they believe is right. This person is willing to make decisions and confident that they are the right ones. People will rely on this person’s authenticity and straight forward manner. This person loves working with autonomy and enjoys a role where they feel in control. People will appreciate their confidence because experience has shown that over time, their instincts and decisions can be trusted. Collaboration Alert:\nThis person may not be as easily influenced by others input or ideas, instead they will push forward or go their own way in what they believe is the right thing to do. This person can be a challenge to manage if they are on the wrong track. This person will clash with a micro-manager. When things do go wrong, they do take ownership of it, and may take that attitude with others. People with this talent can loan it, they provide the confidence for others to take action. Their Confidence is intense around things they believe they can make a judgment decision. They are very independent and their own best advisor.\nTo download the Confidence Theme Talent Guide as a PDF, please login.\nIf you don’t have a login, please register.", "pred_label": "__label__POS", "pred_score_pos": 0.5291067957878113}
{"content": "An operational RNA code relates specific amino acids to sequences/structures in RNA hairpin helices which reconstruct the seven-base-pair acceptor stems of transfer RNAs. These RNA oligonucleotides are aminoacylated by aminoacyl tRNA synthetases. The specificity and efficiency of aminoacylation are generally determined by three or four nucleotides which are near the site of amino acid attachment. These specificity-determining nucleotides include the so-called \"discriminator base\" and one or two base pairs within the first four base pairs of the helix. With three examples considered here, nucleotide sequence variations between the eubacterial E. coli tRNA acceptor stems and their human cytoplasmic and mitochondrial counterparts are shown to include changes of some of the nucleotides known to be essential for aminoacylation by the cognate E. coli enzymes. If the general locations of the specificity-determining nucleotides are the same in E. coli and human RNAs, these RNA sequence variations imply a similar covariation in sequences/structures of the E. coli and human tRNA synthetases. These covariations would reflect the integral relationship between the operational RNA code and the design and evolution of tRNA synthetases.", "pred_label": "__label__POS", "pred_score_pos": 0.9332091212272644}
{"content": "(625ap) Comparison of Predicted and Measured Conversion Performance of Corn Stover, Switchgrass, Miscanthus, and Paper Blends Following Pretreatment and Enzymatic Hydrolysis\nA blended feedstock strategy has been proposed to address the high cost of feedstock access and enable biomass supply systems for biofuel production. Here, measured composition and conversion performance for blends were compared to performance predicted from the weighted average of constituent feedstocks. Corn stover (CS), switchgrass (SWG), paper (MSW), and\nMiscanthus (MIS) were selected for blending. Compositional analysis, dilute-acid or dilute-alkali pretreatment, and enzymatic hydrolysis were performed on feedstocks and blends; sugar yields and feedstock reactivity were measured to assess conversion performance. Predicted glucose yields from combined pretreatment and enzymatic hydrolysis corresponded to measured yields for blends of CS/SWG/MSW and CS/SWG/MIS. There were no significant differences in glucose yield for blends of CS/SWG 80/20 and CS/SWG 50/50 relative to corn stover (p > 0.05). Reactivity results suggest that blending CS and SWG at ratios of 50/50 and 80/20 did not lead to an increase in recalcitrance relative to corn stover. Ternary blends of 65/25/10 and 75/15/10 CS/SWG/MSW had glucose yields from combined pretreatment and enzymatic hydrolysis (0.68 ± 0.03 and 0.72 ± 0.02 g/g, respectively) that were equivalent to corn stover (0.72 g/g ± 0.02). Results suggest that it is possible to formulate blends capable of meeting quality targets and conversion metrics and perform similarly to corn stover in laboratory-scale studies.", "pred_label": "__label__POS", "pred_score_pos": 0.7863278388977051}
{"content": "Ukraine: Industrial output contracts again September\nOctober 22, 2018\nAccording to data released by the Statistical Institute, industrial production dropped 1.3% year-on-year in September, deteriorating further from the previous month’s 0.5% fall. The print marked the weakest reading in 14 months and reflected a marked contraction in manufacturing production as well as a significant drop in output in the electricity, gas, steam and air conditioning supply sector.\nAnnual average growth in industrial output ticked down from 1.6% in August to 1.5% in September. Looking at sequential data, industrial production rose 1.7% month-on-month in September, swinging from the previous month’s 0.5% drop and marking the strongest reading in four months. Ukraine Industrial Production Forecast\nFocusEconomics Consensus Forecast participants project that industrial output will grow 2.9% in 2018, which is down 0.1 percentage points from last month’s forecast. For 2019, panelists expect industrial production to rise 3.2%, which is also down 0.1 percentage points from previous month’s forecast.\nAuthor: Almanas Stanapedis, Economist", "pred_label": "__label__POS", "pred_score_pos": 0.974686324596405}
{"content": "Public officials who control access to scarce resources may profit by extracting extraordinary rents during the economic disruptions that follow epidemics. This can increase the value of holding office during these crises. Using data on the sales of public offices in colonial Mexico, we show that while the negative effects of epidemics limited the value of office in most areas, in districts with a public granary — an institution that regulated grain markets in times of food scarcity — aspiring officeholders were willing to pay more for positions following disease outbreaks. Historical evidence suggests that the differential increase in office prices in areas with a granary can be traced to officials' ability to manipulate food prices and supply for personal gain during crises. This highlights the important roles of economic monopoly and political corruption in determining the consequences of epidemics.\nCompanion\nJournal of Political Institutions and Political Economy, Volume 1, Issue 4 Special issue - The Political Economy of Pandemics, Part I\nSee the other articles that are part of this special issue.", "pred_label": "__label__POS", "pred_score_pos": 0.9446279406547546}
{"content": "GHSE LLC, a Green Cove Springs, Fla. establishment, is recalling approximately 5,682 pounds of salad products containing chicken due to misbranding and an undeclared allergen, the U.S. Department of Agriculture’s Food Safety and Inspection Service announced. The product contains wheat, a known allergen not declared on the product label.\nThe ready-to-eat salads with chili-seasoned chicken items were produced on various dates between May 11, 2016 and June 29, 2016. The following products are subject to recall: 11-oz. plastic clam shell containers with “TRADER JOSE’S MEXICALI INSPIRED SALAD WITH CHILI SEASONED CHICKEN” with “BEST BY” dates 05/18/16 – 07/03/16.\nThe products subject to recall bear establishment number “EST. P-45781” inside the USDA mark of inspection. These items were shipped to retail locations in Alabama, Florida, Georgia, North Carolina, South Carolina, Tennessee, and Southern Virginia.\nThe problem was discovered by a plant quality assurance technician during a routine check of ingredients. The salads have the correct label on the top of the package, but exhibit an incorrect back label that does not include soy sauce as an ingredient; the source of the wheat. As a result, wheat is not sub-listed in the ingredients statement or in the “Contains” allergen declaration.\nThere have been no confirmed reports of adverse reactions due to consumption of these products.\nSource: FSIS", "pred_label": "__label__POS", "pred_score_pos": 0.7182298302650452}
{"content": "As humans, we were not meant to be socially isolated. Social isolation is believed to elevate our stress levels and it can lead us to have feelings of loneliness, fear of others, or even negative self-esteem. Currently, in light of the recent COVID-19 pandemic, considering the mass closures of schools and businesses, instability of employment or employment at home and the tension of the unknown can cause stress to build and lead to increased incidences of domestic violence. Hence, during this time of social distancing and shelter-in-place, domestic violence experts and shelters have expressed deep concerns as to the safety of domestic violence victims, as abusers can use social isolation to gain greater control over their victim, thus increasing the risk of a survivor’s personal safety.\nPer the Illinois Domestic Violence Act (750 ILCS 60), domestic violence is defined as any of the following: physical abuse, harassment, intimidation of a dependent, interference with personal liberty or willful deprivation (but does not include reasonable direction of a minor child by a parent). In a nutshell, harassment includes behavior that is not reasonable and it causes another emotional distress. Examples of emotional distress include creating a disturbance at a place of employment or school; repeatedly telephoning a place of employment, home or residence; repeatedly following someone to a public place or places; stalking (keeping someone under surveillance by remaining present outside their home, school, place of employment, vehicle or by peering into someone’s windows); improperly concealing a minor child; repeatedly threatening to improperly remove a minor child from the physical care of a parent; repeatedly threatening to conceal a minor child or threatening physical force, confinement or restraint on one or more occasions.\n...", "pred_label": "__label__POS", "pred_score_pos": 0.6595555543899536}
{"content": "For most, being quarantined means significantly more screen-time.\nWhether you're using it productively or unproductively, you're likely consuming much more media than before.\nThat can be a double-edged sword. It has the potential to increase your understanding of events – but also increases the likelihood of echo chambers and the intake of misinformation (aka\nfake news).\nSo, in this quarantine, what exactly are people looking at, and how are they staying informed?\nVisualCapitalist put together various infographics on how different generations are consuming content.\nvia visualcapitalist\nUnsurprisingly, younger generations are playing games, and millennials are focusing on food (cooking recipes and staying healthy while quarantined). Meanwhile, the older generations are still sticking primarily to broadcast TV.\nRegardless of where you're consuming, it's important to manage what you're consuming, and how much you're consuming. You need to make sure you're using reliable resources and managing your time and energy. Too much can leave you worse off.\nSometimes, less is more.", "pred_label": "__label__POS", "pred_score_pos": 0.8412143588066101}
{"content": "Abstract\nWhat role does convection play in cloud feedbacks? What role does convective aggregation play in climate? A flurry of recent studies explores “self-aggregation” of moist convection in diverse simulations using explicit convection and interactive radiation. The implications involve upper level dry areas acting as infrared windows—the climate system's “radiator fins.” A positive feedback maintains these: dry columns undergo radiative cooling which drives descent and further drying. If the resulting clumpiness of vapor and cloud fields depends systematically on global temperature, then convective organization could be a climate system feedback. How reconcilable and how relevant are these interesting but idealized studies?.\nKeywords convective aggregation moist convection moist static energy radiative cooling radiative-convective water vapor ASJC Scopus subject areas Global and Planetary Change Environmental Chemistry Earth and Planetary Sciences(all)", "pred_label": "__label__POS", "pred_score_pos": 0.6469501256942749}
{"content": "The global pandemic has driven a significant increase in the utilization of digital health interventions, including a 50%+ rise in the use of telemedicine. While ease in access can remove critical barriers to getting care, by itself, it doesn’t address other factors that determine care decisions, such as consumer behavior and reactive care. This session will explore specific strategies for how to virtualize care in a way that genuinely improves the member experience and health outcomes.", "pred_label": "__label__POS", "pred_score_pos": 1.0000098943710327}
{"content": "British bioenergy fund manager Iona Capital is in the midst of raising its fourth vehicle which could reach up to £250 million ($323.2 million; €296.4 million), Infrastructure Investor understands.\nIona Environmental Infrastructure IV’s hard-cap is significantly higher than the firm’s previous three funds of £70.5 million, £60 million and £45 million. The first two vehicles are now fully invested, while the third is approximately 50 percent deployed.\nThe firm has secured an £80 million cornerstone investment from GLIL, a partnership established by the Greater Manchester Pension Fund and London Pensions Fund Authority which the West Yorkshire Pension Fund, Merseyside Pension Fund and Lancashire County Pension Fund joined late last year. A further £20 million has also been contributed by the Strathclyde Pension Fund.\nHowever, with the pooling of the UK pension schemes slightly diluting its potential UK investor base, Iona is believed to be in negotiations with institutions from the Middle East and Far East, including sovereign wealth funds, to take the fund to its £250 million hard-cap by the end of the year.\nThe new vehicle is expected to target an IRR of about 13 percent, according to the Strathclyde pension scheme. Continuing Iona’s previous strategy of investing in anaerobic digestion plants, biomass combined heat and power and energy-from-waste technologies, it is thought to have a pipeline of over £350 million, with approximately 20 projects in an advance stage of diligence with tickets sizes ranging from £10 million to £40 million. Documents from Strathclyde suggest an initial target for the fund of £150 million.\nPotential investments from the fourth fund are understood to be less dependent on a feed-in tariff from the UK government which was cut last year and could face further decreases. They could also target more complex waste projects than Iona has tackled in the past.\nStrathclyde also noted that compared to elsewhere in Europe, “there is still significant potential for expansion” of bioenergy projects in the UK. Bioenergy generation reached record levels of 29.6TWh last year, according to UK government figures.\nIona Capital declined to comment.", "pred_label": "__label__POS", "pred_score_pos": 0.9847631454467773}
{"content": "As the pandemic continues and more individuals lose jobs and health insurance, the demand for Medicaid and Children’s Health Insurance Program (CHIP) coverage is rising. Kentucky and Virginia – stripped of their traditional, in-person enrollment strategies – have adapted their outreach efforts to help make enrollment as easy as possible for adults and children to ensure access to critical coverage and care.\nBackground\nA recent survey of Medicaid programs shows that between February and May 2020 all but three states experienced notable increases in enrollment.Through waivers and state plan amendments, states have the opportunity to adopt a wide range of flexibile strategies to facilitate and maintain enrollment.\nHowever, social-distancing, tele-work, and strained state budgets have introduced new challenges for state Medicaid and CHIP agencies. A number of state Medicaid agencies have implemented furloughs or reassigned staff to contract tracing and other essential tasks related to the pandemic. Without the ability to conduct traditional outreach campaigns, which are often linked with large community gatherings and one-on-one enrollment support, state Medicaid agencies have needed to quickly pivot their outreach strategies to connect with individuals who are newly eligible for coverage.\nStreamlining Enrollment and Enhancing Partnerships\nKentucky has experienced one of the most significant increases in Medicaid enrollment. Between February and May, 2020, Kentucky’s Medicaid and CHIP enrollment increased by nearly 7 percent. While some of the growth can be credited to the maintenance of effort (MOE) provisions required to secure enhanced federal Medicaid funding through the Families First Coronavirus Response Act, Kentucky has taken significant steps to enroll eligible individuals and families. State officials report that a key aspect of their successful enrollment strategy has been adopting presumptive eligibility (PE) policy flexibilities allowed by the public health emergency. By designating the state Medicaid agency as a qualifying entity to determine presumptive eligibility based on individuals’ modified adjusted gross income, and condensing its 20-page application into a one-page online form, Kentucky has enrolled over 137,000 individuals under presumptive coverage. To keep these individuals covered once their eligibility period ends, Kentucky Medicaid agents track these applications to identify when individuals’ PE periods are drawing to a close. They then make direct outreach calls to these enrollees to assist them in completing a full Medicaid application.\nStates have also leveraged interagency partnerships to target their outreach strategies to individuals who may be eligible for Medicaid coverage. To connect with individuals who may have lost employer coverage due to the pandemic, both Kentucky and Virginia have contacted thousands of individuals who have applied for state unemployment insurance. The states also added easily accessible links to their unemployment agency websites to help individuals to apply for health coverage.\nIn Virginia, partnership efforts have been bolstered through a renewed connection with the Virginia Health Care Foundation’s (VHCF) Project Connect, which funds local outreach efforts to enroll individuals in Medicaid and CHIP. Through this partnership, representatives from Virginia Medicaid and VHCF have provided support at virtual job fairs and rapid response online events, and they plan to continue to collaborate to serve those who have been affected by COVID-19’s economic consequences.\nLike Kentucky, Virginia has also experienced a significant increase in Medicaid enrollment in recent months, and state officials credit the persistence and creativity of their community outreach coordinators as critical to their enrollment success. They have redesigned their approach to safely conduct outreach and enrollment support by leveraging existing community contacts to distribute informational materials electronically and organizing online meetings with community groups. The outreach coordinators have also sought to develop new partnerships with charity, community, and faith-based organizations, retailers, and hospitality groups, as well as schools and colleges. In some rural areas with lower COVID-19 infection rates, the coordinators are beginning to conduct some outreach efforts at churches, fast food chains, and other retailers.\nA crucial focus of this work in both states has been developing targeted outreach strategies and building relationships with communities of color who have been disproportionately affected by the economic and health impacts of COVID-19. Virginia has developed ad campaigns designed specifically to reach Latinx families. Kentucky relies on its data analytics team to guide the state’s outreach efforts and recently launched a marketing campaign targeting seven counties with the highest Black, uninsured population.\nModifying Back-to-School Outreach Efforts\nFor children, who represent 51 percent of total Medicaid and CHIP enrollment, access to health coverage is of paramount importance to ensure that developmental milestones are met and vaccines are administered. Traditionally, school partnerships have provided Medicaid and CHIP agencies with the ability to identify eligible children and families and to distribute resources from a trusted source. A report conducted by the Urban Institute at the Robert Wood Johnson Foundation in 2016 found that almost half of individuals who are eligible for Medicaid or CHIP live in families with at least one school-aged child, making schools a valuable venue to conduct outreach for both children and adults.\nHistorically, the back-to-school season provided an opportunity for Medicaid and CHIP programs to convene large enrollment events where promotional flyers and branded materials are distributed to children and parents. However, this year, without traditional events such as summer camps or sports registration, there are fewer chances to connect with families to provide coverage options and underscore the importance of care.\nIn addition to hosting events, Medicaid and CHIP agencies often provide schools with informational packets to slip into student’s backpacks or include with school registration materials. But with fewer students returning to traditional classroom settings and tighter restrictions on the number of individuals allowed into schools, these tested outreach methods have needed to be re-examined and reformulated.\nTo minimize physical contact, Kentucky has limited school outreach to a group of professionals from the Division of Family Resource and Youth Service Coalition (FRYSC) within the Cabinet for Health and Family Services. Representatives from FRYSC have established relationships with schools and are able to distribute outreach materials without prolonged contact at socially distanced drive-through school events. In recent weeks, FRYSC representatives have begun distributing materials, which include more than 200,000 protective face masks displaying KCHIP marketing for children.\nIn Virginia, the Medicaid agency has revamped its back-to-school campaign by investing in digital resources for students and families. Working with schools, VA Medicaid has created widgets that will send parents from school webpages to the Medicaid and CHIP back-to-school pages. Their reformulated back-to-school websites acknowledge the constraints caused by the pandemic and include information for parents about how to enroll their children in health coverage in both English and Spanish as well as outreach resources for schools, such as social media messaging. When the back-to-school campaign formally ends in December, these dedicated back-to-school pages will be built into their website and remain active throughout the year.\nThe state is also coordinating with a digital engagement contractor to send text messages aimed at parents and advocates to encourage enrollment in CHIP and Medicaid. In addition to outreach efforts through school’s web pages, Virginia Medicaid printed 1.3 million copies of its enrollment materials to cover every school-age child in every public school in the state. Prior to the pandemic, Virginia Medicaid requested that the materials be distributed in back-to-school informational packets, but this year, due to the variability in which districts are electing to return to school, it asked teachers and administrators to distribute the material in any way they saw fit.\nIn response to the limitations of the pandemic, states have demonstrated flexibility in their approaches to outreach and enrollment. Kentucky’s efforts highlight the importance of making enrollment as easy as possible for individuals. Virginia state officials noted that despite the challenges and constraints, COVID-19 has provided the state with an opportunity to reassess and improve its outreach strategies. As Medicaid programs continue to serve as one of the primary safety nets for millions of Americans whose livelihoods have been uprooted by the economic consequences of the pandemic, states are creatively adapting their outreach and enrollment efforts to help ensure access to coverage and care.", "pred_label": "__label__POS", "pred_score_pos": 0.9723251461982727}
{"content": "While everyone and their mom has an ab wheel lying around, rollouts are actually an advanced exercise.\nBut if you have the shoulder mobility for it and you've mastered plank variations already, then ab wheel rollouts might be the most comprehensive exercise you can do to strengthen your midsection.\nWhen done correctly, they'll strengthen your entire anterior core musculature as well as your lower back, lats, and even your shoulder complex. This is crucial if you want a big squat and deadlift since your core is designed to create stiffness to efficiently transfer force from your lower body to your upper body, and vice versa, as well as resist movement at the spine.\nBut the key word is \"correctly.\" Rollouts often get butchered. The usual mistakes? Either initiating the concentric portion of the exercise by pulling the hips back or hyperextending at the bottom. Both take tension off the intended musculature.\nThis variation removes those potential issues to keep continuous tension on the abdominals.\nAb Wheel Rollout with Hamstring Activation\nIf standard rollouts don't place the tension on the abs, try these instead:\nPlace a medicine ball between your lower legs and glutes. Start with your hands on the ab wheel, directly under your shoulders. Keep a straight line between your ears, hips, and knees. This is your start and end position for each rep. Squeeze your heels toward your glutes – crush the ball – and brace your abs. By flexing the knee, your hamstrings will pull your pelvis into a posterior tilt as the ab-brace pulls your ribs down. Keeping your pelvis and ribs in this stacked alignment, think about \"reaching\" over your head as you roll out. Once you get out as far as you can without losing your stacked position, reverse the motion by pushing your hands straight down into the floor, as if you were doing a straight-arm pulldown. Only return to the starting position outlined above. Repeat for 2-4 sets of 5-10 reps.", "pred_label": "__label__POS", "pred_score_pos": 0.8421345353126526}
{"content": "The seventh annual G20 Interfaith Forum concluded its meetings on Saturday after five days of sessions that addressed the COVID-19 emergencies, climate change, social, racial, and economic disparities, environmental challenges, the preservation and safeguarding of sacred sites, and other pressing issues. Originally intended to be held in the Kingdom of Saudi Arabia, host of the 2020 G20 Summit, the conference was conducted virtually in response to the global pandemic. Attendance exceeded 2,000 participants from more than 90 countries. The crisis posed by the COVID-19 pandemic played a central role in the discussions at the Forum. The discussions offered vivid testimony to the need for the world's political leaders to include religious actors in policymaking processes including notably the November 2020 G20 Leaders' Summit in Riyadh. Formal recommendations resulting from the Forum will be shared with G20 leadership in the coming weeks.", "pred_label": "__label__POS", "pred_score_pos": 0.9050480127334595}
{"content": "SEATTLE–(BUSINESS WIRE)–#CROmarket–According to Coherent Market Insights, the U.S. contract research organization (CROs) market is estimated to be valued at US$ 12,174.4 million in 2019, and is expected to exhibit a CAGR of 9.4% during the forecast period (2019-2027).\nKey Trends and Analysis of the U.S. Contract Research Organization (CROs) Market:\nIn order to increase success rate of drug discovery programs and decrease R&D costs, pharmaceutical companies seek to accelerate every stage of drug discovery process, starting from target identification to preclinical drug candidate. Increasing research and development expenditure has led to an increase in number of drug approvals in the recent past. For instance, according to the Pharmaceutical Research and Manufacturers of America (PhRMA), 2018, the overall research and development spending of pharmaceutical and biotechnology companies was around US$ 62.2 billion in 2018 compared to US$ 55.8 billion in 2017, which was majority of all biopharmaceutical R&D spending in the U.S.\nRequest for Sample PDF copy @ https://www.coherentmarketinsights.com/insight/request-sample/3179\nIncreasing adoption of inorganic growth strategies such as acquisition to strengthen service portfolio by major players operating in the market is expected to drive the market growth during the forecast period. For instance, in August 2018, Syneos Health, Inc. acquired Kinapse, a leading advisory and operational solutions provider. This acquisition would help Syneos Health to expand regulatory, safety, and pharmacovigilance consulting and operations. Moreover, In May 2018, Ritter Pharmaceuticals, Inc. collaborated with Medpace: a clinical research organization (CRO), to conduct the first of two pivotal Phase 3 clinical trials for RP-G28 in patients with lactose intolerance (LI).\nFurthermore, increase in strategic collaboration for development of innovative therapies for treatment of various health conditions such as immunological disorder is expected to drive the growth during the forecast period. For instance, in August 2019, Pharmaceutical Product Development, LLC entered into a collaborative agreement with Harbour BioMed (HBM), a global clinical-stage biopharmaceutical company, to conduct clinical studies for its research pipeline on anti-cancer immunotherapy\nKey Market Takeaways: The U.S. contract research organization (CROs) market is expected to exhibit a CAGR of 4.7% during the forecast period (2019-2027), increasing initiatives by key players to innovative services and products for managing the processes ranging from drug development to commercialization. For instance, in March, Parexel International Corporation launched PAREXEL’s Medical Writing Solutions for offering communication services throughout the process of drug development and commercialization. Among size of CRO, large size segment is expected to hold significant share in the U.S. contract research organization (CROs) market over the forecast period, owing to increasing mergers & acquisitions by key players. These large-sized players have acquired numerous small and mid-sized CROs, in order to expand their service offering in different therapeutic areas and service modules such as full service, hybrid, and functional service along with expansion into newer markets. For instance, in May 2017, inVentiv Health and INC Research announced US$ 7.0 billion merger to form Syneos Health, one of the largest outsourcing providers. The merger has led to increase client base for Syneos Health. Major players operating in the U.S. contract research organization (CROs) market include Laboratory Corporation of America Holdings (Covance), IQVIA, Paraxel International Corporation, Syneos Health, PRA Health Sciences, Charles River Laboratoires International Inc. (CRL), Pharmaceutical Product Development (PPD), ICON Public Limited Corporation, Wuxi Apptec, Medpace Holdings, Inc, Medidata Solutions, Inc., Theorem Clinical Research, Pharmaron, Envigo, Clinipace, CMIC Holdings Co., Ltd, EPS International, Synteract, CROMSOURCE, Pharm-Olam, Linical Accelovance, Accumedix, Inc., AlcheraBio LLC, Amarex Clinical Research LLC, Arianne Corporation, Absolute Research Solutions, BioClinica Inc., BioPharma Services Inc., Neurovasc Preclinical Services, Inc., PSI, WCCT Global Inc., RHO, Inc., CATO Research LLC, Spaulding Clinical Research, Celerion, Clindatrix, Inc., Comparative Biosciences, Inc., Axiom Real-Time Metrics, CPC Clinical Research, Axis Clinicals LLC, DP Clinical, Egeen Inc., Grayline, Cmed, Integrium, LLC, MedTrials, Novum, Shin Nippon Biomedical Laboratories, Ltd., KPS Life, Pinnacle Research Group, LLC Promedica International., Alta Science, Prometrika, LLC, 4clinics, and Premier Research. Buy this Report (Single User License) @ https://www.coherentmarketinsights.com/insight/buy-now/3179 Market Segmentations: U.S. Contract Research Organization (CROs) Market, By Service Type: Drug Discovery Preclinical studies Early Phase I – IIa Phase IIa – III Phase IIIb – IV Drug Development Medical Coding and Writing Monitoring Clinical Data Management Bio-statistics Site Management Protocol Development Biomarker Discovery U.S. Contract Research Organization (CROs) Market, By Therapeutic Application: Oncology Cardiovascular Diseases Central Nervous System Diseases Infectious Diseases Metabolic Disorders Immunological Disorders Respiratory Disorders Others U.S. Contract Research Organization (CROs) Market, By Size of CRO: Small Size Medium Size Large Size Company Profiles\nContacts\nMr. Raj Shah\nCoherent Market Insights 1001 4th Ave. #3200 Seattle, WA 98154 Tel: +1-206-701-6702 Email: sales@coherentmarketinsights.com", "pred_label": "__label__POS", "pred_score_pos": 0.5491646528244019}
{"content": "This October for Texas Archeology Month, TARL is offering a series of online lectures, free and open to all. Our first lecture took place on October 15 and is available for viewing below.\nDr. Andrew Somerville, Assistant Professor of Anthropology at Iowa State University, presented on his recent research.\nPeopling of the Americas and the Origins of Agriculture: New Insights on Old Questions from the Tehuacan Valley, Mexico\nThe Tehuacan Valley of Central Mexico is a UNESCO World Heritage Site due to its high biodiversity and rich archaeological record. During the 1960s, excavations led by Richard S. MacNeish registered over 10,000 years of human occupation within the valley and discovered thousands preserved botanical remains, including early examples of domesticated plants such as maize, beans, and chili peppers. Recent studies have returned to the collections recovered by MacNeish and apply new analytical techniques to further our understanding of the ancient history of this region. In particular, stable isotope analysis of animal bones documents significant environmental and dietary changes over time. Additionally, new radiocarbon analyses reveal surprisingly early dates and cause us to reevaluate the timing of the arrival of humans to the region and to North American more broadly. This presentation summarizes these recent findings and discusses their implications to questions about the peopling of the Americas and the origins of agriculture.\nWe have three more talks scheduled for this month. The first two will be streamed live over Zoom and all three will be posted here for future viewing.\nOctober 22: Dr. Adam Schneider of the Cooperative Institute for Research in Environmental Sciences (CIRES), University of Colorado at Boulder, will present “\nA Trade-Friendly Environment: Climatic Influences on Early Bronze Age Maritime Trade Between the Near East and Indus Valley”\nOctober 27: Dr. Casey Wayne Riggs, Steward with the Texas Archeological Stewards Network, will present “\nCareless, Spiny, and Succulent: Terminal Late Prehistoric (A.D. 1250-1535) Plant Foods of the Eastern Trans-Pecos” Clovis Points in Texas: A Further Update to the TCPPS, 4th Edition“", "pred_label": "__label__POS", "pred_score_pos": 0.7058538198471069}
{"content": "Once leaving a detox center, many women must return to the very environment that contributed to their substance use disorder. This is the most vulnerable time for relapse.\nITM transitional housing removes the real and perceived stressors and fears associated with securing safe housing that recovering women encounter, by providing shelter away from toxic environments that hinder their recovery.\nITM was established to provide women released from detox centers with safe transitional housing and support while enrolled in an outpatient program.", "pred_label": "__label__POS", "pred_score_pos": 0.9931890964508057}
{"content": "Cancer patients who receive neoadjuvant therapy followed by mastectomy may not need radiation\nEarly-stage breast cancer patients who exhibit limited lymph node involvement may not require post-surgery radiation therapy (RT) when they receive neoadjuvant chemotherapy before a mastectomy, according to researchers from The University of Texas M. D. Anderson Cancer Center.\nThe findings were reported today at the 50th Annual meeting of the American Society for Therapeutic Radiology and Oncology.\n\"Radiation after surgery has been shown to benefit the survival of patients who have more advanced tumors,\" said Tse-Kuan Yu, M.D., Ph.D., assistant professor in M. D. Anderson's Department of Radiation Oncology. \"However, administering neoadjuvant chemotherapy prior to surgery has changed how radiation oncologists need to approach treating patients with stage one and two breast cancers.\"\nThe retrospective study led by Yu reviewed the cases of 427 women who underwent neoadjuvant chemotherapy and mastectomy from 1985-2004 to observe the value of treating early-stage breast cancer with RT. Of the 427 women, radiation was administered to 253 due to more aggressive tumor features. Those who received radiation more commonly had four or more pathologically involved lymph nodes or lymphovascular invasion.\nSpecifically focusing on those who did not receive RT, researchers looked at whether each patient's breast cancer relapsed over the course of five years to determine if radiation contributed to preventing its return. Of the group of patients who were not treated with radiation, 20 percent of those with four or more pathologically involved lymph nodes after pre-surgery chemotherapy relapsed compared to 4.2 percent of those with one to three involved lymph nodes.\nInterestingly, researchers noted that patients with zero involved lymph nodes after receiving chemotherapy prior to surgery exhibited a zero percent recurrence rate.\n\"Our findings indicate neoadjuvant chemotherapy controlled the cancer and radiation would have been unnecessary for patients with early-stage breast cancer and negative lymph nodes after neoadjuvant chemotherapy,\" said Thomas Buchholz, M.D., Chair, Department of Radiation Oncology at M. D. Anderson, the study's senior author. \"Though additional research is warranted, we can begin to surmise that patients can be spared from radiation therapy if they have been treated with neoadjuvant chemotherapy and have less than three involved lymph nodes.\"\nBy analyzing initial tumor characteristics in each patient, researchers can begin to classify which patients require post-mastectomy radiation to prevent recurrence. To expand on these findings, researchers at M. D. Anderson are planning future prospective clinical trials that would confirm whether radiation can be avoided in selected patients with early-stage breast cancer who are treated with neoadjuvant chemotherapy.\nSource: University of Texas M. D. Anderson Cancer Center\nExplore further\nCitation: Cancer patients who receive neoadjuvant therapy followed by mastectomy may not need radiation (2008, September 24) retrieved 27 November 2020 from https://medicalxpress.com/news/2008-09-cancer-patients-neoadjuvant-therapy-mastectomy.html", "pred_label": "__label__POS", "pred_score_pos": 0.6202158331871033}
{"content": "By Father Hao Dinh, Vicar General& Joshua Bennett, General Counsel\nOn December 9, the Diocese of San José, along with five other dioceses in California, received administrative subpoenas from the California Attorney General’s office requesting documents related to the mandatory reporting of allegations of sexual misconduct with minors by clergy and laypersons within the Diocese from 1996 to the present.\nAt first glance, the word “subpoena” might be startling to some people. However, the Diocese of San José views it as another opportunity for us to review our protocols to safeguard all God’s children, bring about justice, and foster healing for those who have suffered from abuse.\nBefore receiving the subpoena, the Diocese provided the Attorney General with more than a thousand documents that did not affect the privacy rights of victims/survivors or disregard state and federal labor laws regarding personnel files and volunteer records. These documents were provided in response to the statewide administrative review initiated by the Attorney General in May 2019.\nWe, the Diocese of San José, believe that protecting all children, youth, and vulnerable adults and bringing about justice, reconciliation, and healing to all victims/survivors is our sacred duty. When victims/survivors reach out to us, we are committed to accompanying them on a lifetime of healing. We maintain confidentiality for all who report past misconduct while also strongly encouraging them to share their stories with law enforcement.\nWe have a responsibility to protect the privacy and legal rights of victims/survivors, lay employees, lay volunteers, and clergy. In this sense, a subpoena may be good and preferable to an informal request for documents without legal protection. It supports our shared goal of ensuring that the safeguards in place for our children are working as they should while protecting the privacy rights of victims/survivors and complying with state and federal labor laws.\nWe believe that by learning from the past, we can bring about true healing for victims/survivors and our Church. We published our credibly accused clergy list last year and updated and expanded it six months ago after a thorough independent review of diocesan records.\nWe provide ongoing comprehensive services and care to victims/survivors of sexual abuse and encourage anyone who has not previously come forward to do so, first, by contacting the local authorities: police department or sheriff’s office; and second, by making a report to our Office for the Protection of Children and Vulnerable Adults, toll-free at (844) 372-1691 or online via a third-party site,\nopcva.ethicspoint.com.\nWe work tirelessly to ensure a safe environment for all God’s children. We are vigorous in our efforts to prevent the devastating sin of sexual abuse by promoting awareness, requiring accountability, and demonstrating transparency.\nEvery bishop, priest, deacon, employee, and volunteer, who works with children or vulnerable adults, must undergo a criminal background check, complete safe environment training every three years, and adhere to an established code of conduct.\nAll Catholic schools and parish faith formation programs offer annual age-appropriate training for students on interpersonal safety and sexual abuse prevention.\nWe undergo an annual independent audit to ensure full compliance with the articles of protection outlined in the national Charter for the Protection of Children and Young People and the Essential Norms and Statement of Commitment. We have passed this audit every year since its inception in 2002.\nWe believe in doing the right thing. We strictly adhere to a zero-tolerance policy and promptly notify law enforcement and child protective services when abuse is reported, following mandated reporter laws. We cooperate with law enforcement during any necessary investigation.\nWe will not be complacent. We pledge to continue working tirelessly to provide safe and nurturing environments for all and fostering a path of healing and reconciliation for those who have suffered abuse.\nLearn more about what the Diocese of San José has done and is doing in the wake of the clergy abuse scandal by visiting\nwww.dsj.org/safe-environment/promise-to-protect-pledge-to-heal.", "pred_label": "__label__POS", "pred_score_pos": 0.6123155951499939}
{"content": "Description\nProduct innovation, customization and adoption of multi-functional products are driving the mature Western European above-the-neck. With nearly 95% of PPEs being sold through distributors, customer service is a key contributor to the growth of the above-the-neck PPE market in the region.\nAmongst countries, Germany, the United Kingdom & Ireland, and France account for nearly a 56.5% share of the total market, with revenue contributions of €141.8 million, €124.3 million, and €106.5% million, respectively, in 2019. The top 3 manufacturers hold a 48.5% market share by revenue. 3M leads the market with a share of 21-23%, followed by Honeywell with a 14-17% share and Uvex with and 9-11% revenue share. Investments into R&D to develop innovative products, coupled with strategic acquisitions, remain a key driver for market growth in the forecast period. Partnerships are the way forward in the competitive market. For example, Schuberth entered into a partnership with 3M in 2016 to develop head protection PPE. Similarly, Hex Armour entered into partnership with Uvex in 2017. Few notable M&As include 3M’s acquisition of Scott Safety in 2017, and Globus Group’s acquisition of ENHA Gmbh in 2017 and Alpha Solway in 2015. Similarly, with the aim to focus on its core businesses Kimberly Clark sold its welding PPE business to Surewerk in 2017 while 3M sold off its prescription eyewear business to Hoya Vision Care in 2017.", "pred_label": "__label__POS", "pred_score_pos": 0.9908626079559326}
{"content": "Mini-strokes, medically known as transient ischemic attack (TIA), could do more harm to patients than previously thought. Currently, TIA isn't treated with clot-busting drugs as larger strokes are, as it is considered as too mild. However, a new study suggests this may be a mistake and the way TIA is approached must be changed. It was observed by researchers that 15 per cent of patients developed some form of disability 90 days after a mini stroke. Shelagh Coutts, lead author of the study, commented: \"Our study shows that TIA and minor stroke patients are at significant risk of disability and need early assessment and treatment. \"We should be imaging patients earlier and be more aggressive in treating patients with thrombolysis if we can see a blockage no matter how minor the symptoms are.\" It was also observed that those with diabetes were at a greater risk of developing disabilities after TIA. Find the nearest Barchester care home.", "pred_label": "__label__POS", "pred_score_pos": 0.7417005896568298}
{"content": "With this recurring column, Elite Healthcare provides readers with insight related to the legal implications of healthcare – offering practical guidance on scenarios that should be avoidable and providing suggested courses of action when appropriate. The examples provided here are those that all providers should be aware of, but many aren’t or are negligent despite their awareness. Don’t let your practice be compromised.\nTelemedicine Reciprocity: Beware of State-by-State Legislation\nThe practice of telemedicine that crosses over state lines is not permitted everywhere throughout the United States. State law is always the standard. For instance, in New York, the patient on the receiving end of treatment cannot be located in a state that the medical provider is not licensed to practice in. Remember that this standard is not calculated by where the healthcare practitioner in question is located when he or she is providing care and is instead focused on where the patient is located when he or she is receiving medical care.\nIn 29 states, cross-state limited practice is allowed, effectively bypassing state licensing. All healthcare providers involved in telemedicine must know state licensure laws. Consultation with a qualified healthcare attorney is strongly advised before any clinician renders care to a patient through telemedicine means.", "pred_label": "__label__POS", "pred_score_pos": 0.9769821763038635}
{"content": "This blog was written by Bart Lenaerts-Bergman.\nAs cyber criminals move faster and stealthier, taking advantage of new tools provided through an adversarial community, security teams need to be able to respond with equal or greater speed. Every second counts after a cyber attack. Therefore, it is imperative to have a solid plan in place for actions that take place during the moments immediately following an incident or what we call the “Security Golden Hour.”\nIn a recent ESG survey “Tackling Attack Detection and Incident Response” commissioned by McAfee, responders indicated they spend their time on five key tasks. Top of the list included:\n1. Determining the impact of the incident 2. Tacking action to minimize the attack 3. Analyzing security intelligence 4. Determining which assets remain vulnerable 5. Performing forensic analysis\nWhen asked which initiatives would help boost staff efficiency, three SIEM key capabilities came to surface: first of all “better detection tools” to find potential malware accurately, followed by “better analysis tools” and “process automation to free up staff”. These last findings also form the foundation of the seven key actions McAfee’s Enterprise Security Manager (ESM) provides during the golden hour.\nThe first group of SIEM actions is related to the identification of the threat. Importance here is to reduce false positives and bring quickly and accurately potential adversarial activity in front of the security analyst. McAfee ESM advanced analytics (action #1) provides an overview who, when and where valuable infrastructure is used. During this analysis, ESM will calculate baselines, bring known and unknown threats to surface via rule and risk-based correlation, and leverage enterprise contextual information for better insights. A second action (#2) that ESM supports includes the collection and harvesting of threat intelligence. This step helps users to identify threats based on the misfortune of others and confirms the security analyst if the threat has already been seen somewhere else. A unique third action (#3) from McAfee ESM is both real time and historical correlation. Where most SIEM’s will only leverage threat intelligence going forward, McAfee ESM verifies if the organization has already been impacted by a known IOC (Indication of Compromise) via the BackTrace feature.\nAfter the identification, users need to review, prioritize and decide on what to do next. During this second phase, visualization (#4) and isolation (#5) of threat activities are the next key actions SIEM should provide. Pre-built or custom dashboards, with fast and easy access to data, allow the user to run investigations quickly and reduce the time to prioritize the threat. Additionally, Asset Threat Risk dashboards aggregate known external threats, assets vulnerabilities and available countermeasures to help the security analyst pinpoint which enterprise assets are truly at risk.\nIn the last step, the incident responder acts by eradicating (#6) the adversary and communicating (#7) the required actions within the IT operations teams. These 2 actions can be taken directly from the console or can be fully automated to optimize security resources. Via built-in case management tool, the security operations manager can review open and closed Incident response tasks as well as spot recurring incident types for improved automation.\nReview examples of known threats, SIEM best practices and the 7 key SIEM actions in a recent Secure World Webinar: https://goto.webcasts.com/starthere.jsp?ei=1056214\nRead the ESG study: https://www.mcafee.com/us/resources/reports/rp-esg-tackling-attack-detection-incident-response.pdf", "pred_label": "__label__POS", "pred_score_pos": 0.5402679443359375}
{"content": "Providing resources and trainings for applicants and operators is a key authorizer responsibility. By offering guidance and direction to existing and future schools, authorizers can articulate expectations, anticipate and answer questions, assist the creation of EL programs and staffing models, and establish evaluation criteria.\nDenver Public Schools\nDenver Public Schools (DPS), for example, offers a thorough, thoughtful “English Language Acquisition Guidebook for Charter Schools” that walks readers through the applicable legal requirements, the role of the district, federal, and state funding streams, teacher certification requirements, English language development requirements, assessments for EL students, parent engagement strategies, translation/interpretation service requirements, and service provider recommendations. This guidebook is written exclusively for charter schools; it serves as a comprehensive resource for applicants, existing schools, students, and families, and it clearly explains what is expected of schools as they develop English language programs for their students.\nLos Angeles Unified School District\nThe Los Angeles Unified School District (LAUSD) also offers a very rich, comprehensive resource for designing and delivering an EL program, though it is not written exclusively for charter schools. Rather, LAUSD has created an “English Learner Master Plan” for its traditional district schools; this Master Plan includes a section on charter schools which explains that charter schools may adopt LAUSD’s Master Plan or must provide LAUSD, as the authorizer, an alternative, proposed, EL services program that effectively meets the language needs of EL students. The LAUSD Master Plan sets forth the requirements a charter school’s EL program must satisfy–both during the application phase and annually thereafter. Notably, even though the LAUSD Master Plan expressly exempts from its requirements charter schools that seek to develop independent EL programs, the detail and rigor of the Master Plan may serve as a tool and idea hub for charter applicants and operators as they design and implement their own EL programs.\nMassachusetts Department of Education\nThe Massachusetts Department of Education (MDE) takes a different and equally effective approach in supporting its charter schools. Instead of publishing a comprehensive guidebook, the MDE assembles and updates a webpage with EL resources; this compendium of material includes self-evaluation templates as well as information on legal requirements, assessments, funding, and curriculum models. These resources provide practical guidance to charter applicants and operators, outlining broad strokes of what is expected and allowing operators to design their own EL programs adhering to the broad parameters set up by the MDE.\nDistrict of Columbia Public Charter School Board\nThe District of Columbia Public Charter School Board (DCPCSB) has provided regular trainings for schools as part of its efforts to ensure that charter schools in the District of Columbia are effectively serving EL students. DCPCSB has also offered “office hours” during which schools can consult with the general counsel and other knowledgeable staff about EL program requirements. While the general counsel/staff do not provide legal advice, they are able to point schools in the right direction or give them guidance on where they may need to do more work.", "pred_label": "__label__POS", "pred_score_pos": 0.9219738245010376}
{"content": "A key issue is whether the contract to deliver a non-financial item (a commodity) falls within the scope of IAS 39 Financial Instruments. Though IAS 39 would appear to apply only to financial assets and financial liabilities, certain contracts for non-financial items are also within its scope.The same issue applies to those entities that have adopted IFRS 9 Financial Instruments early, as its scope is the same as that of IAS 39. In determining whether the contract falls within the scope of IAS 39, it is necessary first to determine whether the contract permits:\n– Net settlement in cash or in another financial instrument; or – Can be settled by exchanging financial instruments, as if the contract itself is a financial instrument. Given the facts in this case it is unlikely that you should recognize this as a financial asset. Check this link for more info: http://bit.ly/18ghpM3", "pred_label": "__label__POS", "pred_score_pos": 0.792299211025238}
{"content": "In view of the developing coronavirus (nCoV) situation, CapitaLand has closed all four of its malls in Wuhan and both of its malls in Xi'an. These six CapitaLand malls in Wuhan and Xi’an will reopen depending on the condition and directives from local government.\nThe Chinese government had also issued a directive that CapitaLand’s office properties in places such as Shanghai, Zhejiang, Guangdong and Chongqing will be closed until 9 February 2020. However, the supermarkets in CapitaMall Westgate, Wuhan and CapitaMall Xindicheng, Xi’an will remain open to ensure the supply of food and daily essentials to the local communities. Meanwhile, the remaining 45 malls in CapitaLand’s retail network across China, which are located in cities such as Beijing, Chengdu, Guangzhou and Shanghai, will continue to operate with shorter hours.\nAccording to CapitaLand, it has adopted the necessary precautionary measures in accordance with guidelines from the health authorities, and will continually review its properties’ operating hours in line with local conditions and regulations. All of CapitaLand's properties in China will also undergo temperature checks, as well as cleaning and disinfecting of common areas. CapitaLand will also conduct contact tracing and have designated premises at its properties for the isolation of persons suspected to be infected with the virus.\nMeanwhile in Singapore, CapitaLand has implemented precautionary measures in accordance with guidelines from the authorities and has placed hand sanitisers for tenants, shoppers and guests in the properties. The real estate company has also created designated premises with predetermined routes within its properties for the isolation of persons suspected to be infected with nCoV. CapitaLand will also be stepping up cleaning efforts and aims to take precautionary measures further where necessary. The company has also put in place business continuity plans (BCP) to enable the group to continue its critical activities and minimise impact to operations.\nLee Chee Koon, group chief executive officer, CapitaLand Group said that the company has set up a special task force to coordinate its response across its operations in China and in the various markets it operates in. He added that to date, CapitaLand's business operations, including in China and Singapore, remain largely stable.\n\"Our priority is to focus on ensuring the well-being of our tenants, shoppers, guests and employees. We are all in this together during these trying times. CapitaLand will continue to work closely with the different local authorities in our markets to offer our support,” he said.\nManohar Khiatani, senior executive director of CapitaLand Group, who has been appointed as the group BCP commander, said CapitaLand’s business continuity plans guide its operations which includes how and when to limit the interaction of business-critical staff. This includes working from alternate sites, working from home and the use of teleconferencing. \"Where necessary, operational personnel will be divided into primary and alternate teams. We will continue to monitor developments and the authorities’ directives, take the necessary steps to minimise impact to our operations and update our stakeholders in a timely manner,” he added.\nSimilarly, Singapore-listed tourism firm Straco Corporation has temporarily closed three of its attractions in China, namely Shanghai Ocean Aquarium, Underwater World Xiamen and Lixing Cable Car. This move comes as the company looks to prevent the spread of coronavirus in the People’s Republic of China. According to Straco, the company will continue to monitor on updates and advisories from the local authorities. Straco has also instituted precautionary health and hygiene measures, including cleaning and disinfection of facilities and necessary screening of its employees. On a separate note, Straco also temporarily suspended Singapore Flyer's flight operations in August 2019 due to a minor technical issue and has yet to resume operations.\nSingapore-listed real estate investment company Dasin Retail Trust has shortened the business hours of its shopping malls. These include Shiqi Metro Mall, Xiaolan Metro Mall, Ocean Metro Mall, Doumen Metro Mall and Dasin EColour. The respective malls’ business hours were shortened with the exception of the provision of basic public services such as supermarkets and certain F&B outlets. In addition, cinemas, KTVs, ice skating rings, bookstores and other crowded places will be temporarily closed. Currently, Dasin Retail Trust's shopping malls have issued guidelines to prevent coronavirus that includes requiring staffs, tenants and all personnel entering and leaving the malls to wear face masks. The company will also cooperate with government departments to carry out epidemic inspection and conduct temperature tests on people entering the malls.", "pred_label": "__label__POS", "pred_score_pos": 0.5482411980628967}
{"content": "The global\nbubble tea market size is expected to reach USD 4.2 billion by 2027 registering a CAGR of 8.9%, according to a new report by Grand View Research, Inc. Shifting consumer preference from carbonated drinks to zero-fat hot beverages, such as bubble tea, is expected to be the key factor for the market growth.\nAsia was the largest regional market in 2019 and accounted for 35% of the global share. The region will retain its dominant position throughout the forecast years on account of high consumption of bubble tea in countries including Taiwan, China, and Thailand. In addition, according to the ASEAN Post, which was published in December 2019, the average consumption of bubble drinks in Thailand was six cups per person per month.\nMajor companies in this market are expanding their global presence through various business strategies. For instance, in September 2019, The Alley, a renowned Taiwanese restaurant chain, inaugurated its first restaurant in New York City. Thus, increasing number of restaurant chains specialized in bubble hot beverages is anticipated to boost market growth over the forecast period.\nClick the link below: https://www.grandviewresearch.com/industry-analysis/bubble-tea-market Further key findings from the report suggest: Black tea segment held the major share of more than 45% in 2019 and is estimated to expand further at a steady CAGR over the forecast period Green tea product segment is anticipated to register the fastest CAGR from 2020 to 2027 owing to various health benefits of this beverage Fruit flavor led the flavor segment in 2019 accounting for the largest market share. It is projected to maintain its leading position throughout the forecast period Asia Pacific was the largest regional market in 2019 and will grow further at a significant CAGR from 2020 to 2027", "pred_label": "__label__POS", "pred_score_pos": 0.581588089466095}
{"content": "The global\nmulti-mode receiver market size is expected to reach USD 1.3 billion by 2025, according to a new study by Grand View Research, Inc., recording a 4.4% CAGR during the forecast period. Multi-mode receiver (MMR) plays a crucial role in augmenting navigation and landing capabilities of an aircraft. As a result, the number of aircraft deliveries emerges as a crucial factor for the MMR market. Although worldwide aircraft shipments have dropped from 2,331 in 2015 to 2,262 in 2016 as stated by the General Aviation Manufacturers Association (GAMA), air passenger traffic has increased significantly over the past 10 years, particularly in developing economies such as India and China. This is expected to propel market growth.\nAn MMR integrates multiple functionalities into a compact unit, thereby reducing the weight and space factor of an aircraft. It also assists the pilot in positioning, navigating, and landing the aircraft, even in unfavorable conditions. These factors are likely to work in favor of the MMR market.\nAnother important factor contributing to market growth is initiatives undertaken by airlines across the world to modernize their fleets. Stringent mandates have been laid down for the aviation sector worldwide. At the same time, new technologies such as Automatic Dependent Surveillance-Broadcast (ADS-B) Out are also emerging. While airlines are undertaking various aircraft modernization programs and upgrading their fleets, they also have to make sure their aircraft support the latest technologies and evolving Required Navigation Performance (RNP) navigation approaches. As a result, airlines are spending aggressively on advanced navigation systems. However, safeguarding aircraft avionics systems/technologies from cyber-attacks is one of the crucial challenges faced by the aviation industry.\nAt present, a handful of market players holding expertise in manufacturing MMR systems are dominating the market. The strong geographical presence of these incumbents, coupled with existing long-term supply contracts, will ensure steady growth of the MMR market over the forecast period. Market players are also adhering to strategies aimed at new product development and expansion in order to strengthen their foothold in the market. For instance, in 2017, Honeywell International Inc. developed a new integrated MMR that complies with GLS CAT-III navigation standards.\nClick the link below: https://www.grandviewresearch.com/industry-analysis/multi-mode-receiver-mmr-market Further key findings from the study suggest: The retrofit segment is expected to exhibit a CAGR higher than that of the line-fit segment, as airlines remain keen on retrofitting their aircraft with the latest avionics The fixed-wing segment is anticipated to register the highest CAGR over the forecast period in line with the increasing number of aircraft being delivered in developing economies of Asia Pacific The North American region held a market share of 43.0% in 2016 as a result of strong demand from major aircraft manufacturers such as Bombardier and Boeing While MMR helps reduce power consumption, it also happens to be lighter and smaller as compared to receiver solutions available in the market at present. Such favorable factors would ensure steady growth of the MMR market over the forecast period Players such as BAE Systems; Honeywell International Inc.; Leonardo S.p.A.; Rockwell Collins; and Thales Group are dominating the market leveraging their technical expertise.", "pred_label": "__label__POS", "pred_score_pos": 0.7981171607971191}
{"content": "Capgemini’s World InsurTech Report 2019 established that the insurance industry is gradually shifting to a marketplace model in which firms collaborate with ecosystem players to create a bundled set of offerings. In my opinion, the principal objective of a marketplace model is to give policyholders a holistic experience – to engage them with meaningful encounters at multiple touchpoints. A marketplace model also enables insurers to recommend products during life events when customers might need coverage most.\nI believe the marketplace model offers numerous benefits, including exposure to potential partners. Traditional insurers and InsurTechs are interested in collaborative partnerships with companies around the globe from both financial services and non-financial services sectors.\nInsurance industry partnerships – interest from incumbents vs InsurTechs (%), 2019\nAmong others, partnerships between established insurers and InsurTechs allow both parties to gain by leveraging the strengths of the other. We know that through collaboration InsurTechs can leverage incumbents’ industry expertise, brand value, and vast customer data while incumbents can acquire new capabilities based on emerging technologies such as artificial intelligence and advanced analytics by partnering with InsurTechs. The upcoming World InusrTech Report highlights that collaboration also allows industry players to acquire capabilities in the fastest and cost-effective manner, with the trade-offs being lack of control over the solution and no differentiation.\nThe road to a flourishing partnership, however, is not without challenges.\nExpectation gaps\nThe World InsurTech Report 2019 identified disconnects in expectations between traditional insurers and InsurTechs when defining the critical building blocks for the new insurance marketplace. Perceptions around the value of collaboration were particularly disparate.\nMore than 60% of InsurTech firms said they could help incumbents develop a holistic technology infrastructure through collaboration, while less than 40% of incumbents shared the opinion. When asked about data security, only 25% of InsurTechs and 10% of insurers said the issue had collaboration potential, even though data breaches are a hot topic in the industry.\nTherefore, with substantial gaps in expectations and capabilities, fruitful collaboration that drives marketable industrialized products can be challenging to establish.\nThird parties can facilitate collaboration\nAn external partner can help bring established insurers and InsurTechs to the collaboration table. Capgemini’s ScaleUp Qualification Program facilitates collaboration between established financial services firms and mature startups. It offers a 360-degree assessment of a mature startup’s readiness to collaborate incumbents effectively.\nThe process identifies four pillars for effective collaboration between incumbents and newcomers. Each startup’s maturity to partner with a large insurer is evaluated based on its ability to:\nPut the right people in the right position Financially support the business to stay in the market for the long run Gain market traction that delivers measurable success Provide technology tools that are secure and enable frictionless collaboration, as well as scalability.\nScaleUp Qualification outlines an innovation-as-a-service solution to accelerate cooperation from the initial partnership agreement to successful product industrialization. For large insurers seeking to restructure and begin a joint business venture, the plan offers a step-by-step Diagnose, Scout & Design, Orchestrate, and Industrialize process.\nA four-step process to launch a joint insurance business solution\nWith a comprehensive solution for both insurers and InsurTechs, third-party facilitators create an environment where these firms can collaborate to create an integrated set of offerings.\nFor more insights on insurer-InsurTech collaboration and how other external partners can facilitate this collaboration, download Capgemini’s World InsurTech Report 2019.\nAdditionally, keep an eye out for the 2020 report to be published in September – it explores various approaches to acquiring solutions and offers an insight into the key trade-off factors that industry players must weigh in while choosing to collaborate. Register for your free copy of the report, and feel free to connect with me on social media to exchange ideas about this topic.", "pred_label": "__label__POS", "pred_score_pos": 0.8418247699737549}
{"content": "Abstract\nCapacitive deionization (CDI) is an emerging technology with great potential to be energy efficient and allow cost-effective operation for the removal of salt ions from saline water. The introduction of flow electrode to CDI greatly enhanced the salt removal performance at much higher salt concentration, even at seawater level, due to not needing a discharging process, which is required for conventional CDI desalination. Since the oxidation of carbon electrodes and water electrolysis leads to the decrease in desalination performance and long-term stability of the CDI cell, it has typically been operated at the potential difference < 1.2 V. However, due to the various resistances of CDI components, it is known that the electrode potential is lower than the applied cell potential difference. Based on such knowledge, in this study, we operated FCDI desalination at various operational potential differences from 1.2 to 4.5 V, and studied the carbon oxidation and electrochemical characteristics by FT-IR, Raman spectroscopy, and EIS measurements. Desalination efficiency and salt removal rate increase with higher operational potential difference. Our results confirmed that up to 2.5 V, no noticeable carbon oxidation and gas generation resulting from water electrolysis occurred.\nBibliographical noteFunding Information:\nThis work was supported by the Korea Institute of Energy Technology Evaluation and Planning (KETEP) and the Ministry of Trade, Industry & Energy (MOTIE) of the Republic of Korea (No. 20184030202130 ). This work was also supported by the Soonchunhyang University Research Fund .\nAll Science Journal Classification (ASJC) codes Analytical Chemistry Filtration and Separation", "pred_label": "__label__POS", "pred_score_pos": 0.7942448258399963}
{"content": "Tag: voluntary environmental programs\nThis semester, I had to do a literature review for my Foundations of Public Policy class, so I chose a topic that I’m particularly interested in after working on Berklee’s STARS report: voluntary environmental standards. I wondered if they actually worked. My conclusion, after much research, was: kinda. Voluntary environmental programs are indeed more flexible […]", "pred_label": "__label__POS", "pred_score_pos": 0.894011914730072}
{"content": "The ability to retrieve molecules based on structural similarity has use in many applications, from disease diagnosis and treatment to drug discovery and design. In this paper, we present a method to represent protein molecules that allows for the fast, flexible and efficient retrieval of similar structures, based on either global or local attributes. We begin by computing the pair-wise distance between amino acids, transforming each 3D structure into a 2D distance matrix. We normalize this matrix to a specific size and apply a 2D wavelet decomposition to generate a set of approximation coefficients, which serves as our global feature vector. This transformation reduces the overall dimensionality of the data while still preserving spatial features and correlations. We test our method by running queries on three different protein datasets that have been used previously in the literature, basing our comparisons on labels taken from the SCOP database. We find that our method significantl...", "pred_label": "__label__POS", "pred_score_pos": 0.8653280735015869}
{"content": "Abstract\nAs we enter an era of precision medicine and targeted therapies in the treatment of metastatic cancer, we face new challenges for patients and providers alike as we establish clear guidelines, regulations, and strategies for implementation. At the crux of this challenge is the fact that patients with advanced cancer may have disproportionate expectations of personal benefit when participating in clinical trials designed to generate generalizable knowledge. Patient and physician goals of treatment may not align, and reconciliation of their disparate perceptions must be addressed. However, it is particularly challenging to manage a patient's expectations when the goal of precision medicine—personalized response—exacerbates our inability to predict outcomes for any individual patient. The precision medicine informed consent process must therefore directly address this issue. We are challenged to honestly, clearly, and compassionately engage a patient population in an informed consent process that is responsive to their vulnerability, as well as ever-evolving indications and evidence. This era requires a continual reassessment of expectations and goals from both sides of the bed.\nASJC Scopus subject areas Oncology Cancer Research", "pred_label": "__label__POS", "pred_score_pos": 0.977207601070404}
{"content": "VOLUME CONFORMANCE\nManaging the SEPA Cards Standardisation Volume (including Functional and Security requirements) is an intensive self-regulatory project based on market consensus. Whilst favouring technical interoperability and convergence, all contributors must work in accordance with applicable rules and regulations governing competition matters.\nA check of SEPA conformance is currently not performed by EU regulatory authorities. The Volume requirements are thus not formally imposed on market stakeholders. However, its rules are defined by market experts, and the ECB and the European Commission provide guidance and actively contributed to this work.\nVia a Process known as ‘Labelling’, organisations (Specification Providers such as, but not only, Schemes) have the opportunity to declare the conformance of their requirements to the latest release of the Volume. This is managed by the ECSG body known as the ‘Volume Conformance Management Committee’ (VCMC). By undertaking this process, an organisation has the opportunity to make public its effective integration of all the requirements found within the Volume. This offers several advantages as it is a healthy check to assess the extent of alignment with the industry requirements contained in the “Volume”. It also shows commitment to the SEPA vision and can be leveraged in external communications. While conformance of the specification to the “Volume” is managed through the labelling process, the compliance of a solution with the specifications o is controlled through a separate Certification process outside of the scope of the ECSG activities. Equally, existing “type-approval” processes lie outside of the ECSG boundaries and are not impacted by the “Labelling” process.\nWhilst the Labelling process is optional, any Specification Provider which wishes to have a Volume Label for a given Implementation Specification must follow the \"Labelling\" process defined in the Volume.\nThis Labelling process is based on the principles of a self-declaration procedure by the Specification Provider.", "pred_label": "__label__POS", "pred_score_pos": 0.6212413311004639}
{"content": "This Special Collection includes Cochrane Reviews on the following topics: medication; behavioural support; and gradual quitting. Interventions that mimic the act of smoking, notably e-cigarettes, have been excluded from this collection as the risks associated with their use in relation to the current pandemic are not clear. Cochrane Tobacco Addiction are working to remain up to date on all the relevant information, to provide support to people attempting to stop smoking during this difficult time.\nSARS-CoV-2, corona virus, COVID-19, smoking, smoke exposure, tabaco, Prevention, community health, addiction,", "pred_label": "__label__POS", "pred_score_pos": 0.842484712600708}
{"content": "Research conducted by the London School of Business and Finance revealed that two-thirds of millennials would change careers if they could, underpinning this generation’s “job-hopping” reputation. Interestingly, the same figure stood at 47% for the workforce as a whole, suggesting that many of us, not just millennials, are looking for more meaning from our life at work.", "pred_label": "__label__POS", "pred_score_pos": 0.9993696212768555}
{"content": "It also makes the business a subject matter expert in a specific niche.\nThis piece suggests how prospects can be converted to buyers using content marketing. Content must be kept concise to avoid rambling and redundancy. Content marketers should know how to tell a complete story in the fewest words possible.\nThe aim must be to keep content easily readable, interesting, engaging and informative. However, many marketers end up creating content that interests them rather than what would interest a prospect. They must be mindful that a product could interest consumers only if it solves a core concern or desire.\nBrands must become active publishers of content in their niche. They must deliver key messages through documents published in editorial format like webcasts and white papers. This lends credibility to the messages.\n[6 minute read]", "pred_label": "__label__POS", "pred_score_pos": 0.9989771842956543}
{"content": "Freedom isn’t free. It requires blood, sweat and tears. However, freedom is the ultimate prize for rising to meet the rigorous demands of a challenge.\nIn my many years of coaching and consulting, I’ve found that, in virtually every case, the decision to rise to meet a challenge boils down to the desire for greater freedom in one’s life.\nThis includes freedoms from and freedoms to. …FREEDOM FROM the monkey on your back. …freedom from self-imposed limitations. …freedom from the opinion of others. …freedom from the shackles of debt. …freedom from self-limiting beliefs. …freedom from the comfort zone. …freedom from settling for less. …freedom from the masses. …freedom from fear. …FREEDOM TO focus on projects you find important. …freedom to succeed or fail on your own terms. …freedom to doodle, wander and experiment. …freedom to think and dream without limits. …freedom to set and control the agenda. …freedom to showcase your talents. …freedom to set your own schedule. …freedom to say no without guilt. …freedom to love passionately. …freedom to be authentic.\nTo enjoy these freedoms requires that you\nrise to the challenges life presents and pay the required price, in full, in advance, and without complaint.", "pred_label": "__label__POS", "pred_score_pos": 0.989210844039917}
{"content": "Intersectionality\nThe term “intersectionality” was originally coined by Kimberlé Williams Crenshaw in 1989. I was surprised to learn that the term had not formally existed before then. Intersectionality, or the idea that our identities overlap and intersect in unique ways, seems fundamental to the human experience. The conceptual framework for intersectionality originally emerged from Crenshaw’s perspective on the black female experience. In her paper, “Mapping the Margins: Intersectionality, Identity Politics, and Violence Against Women of Color” she articulates this:\n“Contemporary feminist and antiracist discourses have failed to consider the intersections of racism and patriarchy.” (page 1) Personal Experience\nI am intrigued by how individuals tend to emphasize certain aspects of their identities. It seems like a lot of the time when discussing issues of diversity and inclusion, we tend to focus on the aspects of our identity that are disadvantaged or oppressed. For example, when discussing race, white women tend to gear the conversation toward issues of gender instead (Stolzman, 2004). I recall a conversation I had with a classmate once that highlights this point. He was a white male but insisted that he was not privileged and had more disadvantage than other people (e.g., people of color or women) because he grew up poor. While all of these things are certainly legitimate parts of his identity, he seemed to conceptualize them as completely separate and unrelated. Instead, intersectionality asks us to consider how the different parts of our identity come together to shape our experiences and opportunities. This student’s perspective was problematic because he did not seem to recognize how his white-ness and male-ness may give him certain advantages, despite his low-income background. This type of perspective seems especially problematic because it is perhaps not always productive to try and\nquantify who has more or less disadvantage given their identities. Instead, taking an intersectional approach, we can respect how our multiple identities give us qualitatively different experiences. Moving Forward\nI am guilty of (unknowingly) engaging in the behavior described by Stolzman (2004). Moving forward, I’d like to be more conscious of my own intersectional identity, acknowledging that my experience as a woman is also influenced by more privileged aspects of my identity. Taking a more holistic approach in conversations of diversity and inclusion will help me more accurately understand others’ experiences.\nIn my research, I will strive to be more cognizant of intersectionality in the populations that I study. For example, a lot of my work examines how socioeconomic disadvantage impacts brain development and psychopathology. However, it is somewhat incomplete to consider the effects of socioeconomic status without also considering how issues of class intersect with race.\nOn a more macro level, Crenshaw describes the structural inequalities related to intersectionality. For example, women of color experience both racial and gender oppression, which makes them more likely to also be burdened by socioeconomic disadvantages. I hope that some of these structural barriers can be remedied through community resources and legislative change, though it will not be easy to dismantle such a long history of oppression.", "pred_label": "__label__POS", "pred_score_pos": 0.5110683441162109}
{"content": "Abstract\nThis paper investigates how the demand for residential real estate depends on age and other demographic characteristics at the household level. Based on a detailed cross-sectional survey of English households, it finds that housing demand is significantly determined by a household’s human capital, and that housing demand generally increases with age. After retirement it declines, but only to a small extent. High education levels, good health, and high income will increase a household’s demand for housing even when households age. These results are relevant for countries that experience population shrinkage, but where total housing demand could still grow in the future despite stagnating household numbers and aging populations. The paper further shows that changes in demographics lead to very heterogeneous demand responses for different housing attributes, providing information regarding the future qualitative demand for housing.\nKeywords Housing demand Demographics PRICES MODELS MARKETS", "pred_label": "__label__POS", "pred_score_pos": 0.5472614765167236}
{"content": "Protons (ionized hydrogen) in the solar wind frequently exhibit distincttemperatures ($T_{\\perp p}$ and $T_{\\parallel p}$) perpendicular and parallelto the plasma's background magnetic-field. Numerous prior studies of theinterplanetary solar-wind have shown that, as plasma beta ($\\beta_{\\parallelp}$) increases, a narrower range of temperature-anisotropy ($R_p\\equiv T_{\\perpp}\\,/\\,T_{\\parallel p}$) values is observed. Conventionally, this effect hasbeen ascribed to the actions of kinetic microinstabilities. This study is thefirst to use data from the Magnetospheric Multiscale Mission (MMS) to exploresuch $\\beta_{\\parallel p}$-dependent limits on $R_p$ in Earth's magnetosheath.The distribution of these data across the $(\\beta_{\\parallel p},R_p)$-planereveals limits on both $R_p>1$ and $R_p<1$. Linear Vlasov theory is used tocompute contours of constant growth-rate for the ion-cyclotron, mirror,parallel-firehose, and oblique-firehose instabilities. These instabilitythresholds closely align with the contours of the data distribution, whichsuggests a strong association of instabilities with extremes of ion temperatureanisotropy in the magnetosheath. The potential for instabilities to regulatetemperature anisotropy is discussed.", "pred_label": "__label__POS", "pred_score_pos": 0.9223363995552063}
{"content": "Avoids labour shortages in a booming industry\nIn the years ahead, the B.C. construction industry will need all the help it can get. With $115 billion in projects currently underway and another $206 billion in proposed future projects, BCCA forecasts an accumulated labour shortfall of over 7,900 skilled workers by 2028.\nThe trades sector is a key economic driver throughout British Columbia. It employs about 180,000 workers out of a total of more than 242,000 construction jobs. Yet, despite a strong sector performance—up 17% since 2014— a severe labour shortage exists, especially in the skilled trades sector.\nBoosting diversity is good for business!", "pred_label": "__label__POS", "pred_score_pos": 0.5075575113296509}
{"content": "Abstract : A diary approach was used to explore location-sharing preferences of 126 parents with young children with the goal of investigating which elements play a role in their decision to share their location. During a 3-week user study, we daily collected parents’ preferences of location sharing along with data related to the physical and social context, their interest in socializing with other parents and their emotional states. Our analysis points out several insights for this previously underexplored user group. In particular, our results suggest a relative greater importance of the context, both physical and social, with respect to individual traits such as personality, trust dispositions, and demographic characteristics. Moreover positive and negative emotions seem to influence the intention to share location information in a peculiar way: positive moods like happiness seem to encourage private sharing with selected people such as partner, relatives, friends and nearby parents, yet, when parents experience a negative mood, such as being worried, angry or sad, their intention to share publicly on the web is higher.", "pred_label": "__label__POS", "pred_score_pos": 0.9330944418907166}
{"content": "In April of 2019, the Food and Drug Administration (FDA) approved its first HIV-related drug of the year. Marketed as Dovato, it is the first approved combination of dolutegravir and lamivudine. Both of these drugs have been commonly prescribed to HIV patients, but the combination of the two has not been thoroughly tested. Despite its FDA approval, Dovato has drawn some skepticism from doctors and medical experts. It is not the only HIV medication that has raised questions, however.\nAnother popular HIV medication, Truvada, has seen some additional warnings required by the FDA since its initial release. Despite these changes and the reported problems that brought them about, the FDA has done little to address the issues with this drug.\nShoward Law Firm has begun its own investigation into these HIV drugs. Our skilled team has received reports of bone loss and kidney disease linked to Truvada and other TDF-based HIV meds. We are working diligently to establish if Big Pharma has put HIV patients at risk. A successful HIV medications lawsuit could result in significant financial compensation for a patient’s medical injuries. This compensation could include money to cover medical bills, pain and suffering, and emotional trauma. If you believe you have a claim related to HIV medication injuries, contact us immediately to schedule your free, no-obligation consultation.\nFDA-Approved HIV Drugs\nThe FDA has steadily approved drugs designed to combat HIV since the late 1980s. Since that time, the options for HIV patients has only grown. In the early years, doctors began prescribing a number of medications to combat the spread of HIV. However, in recent years, pharmaceutical companies have focused on combinations of these medications. Today, the most commonly prescribed HIV medications include Truvada, Stribild, Viread, and Complera. A new drug known as Dovato has also been recently approved.\nTruvada\nTruvada is an HIV medication manufactured by Gilead Sciences. This drug consists of a mixture of emtricitabine and tenofovir disoproxil fumarate, or TDF. TDF antiretroviral drugs are a common form of treating HIV. However, they also have been linked to cases of kidney and bone damage. TDF drugs are an important part of Gilead’s portfolio. In 2018, the drug maker earned $3 billion from Truvada alone.\nTruvada FDA Approval\nTruvada was first approved by the FDA in 2004 for treatment of HIV and again in 2012 for use as an HIV pre-exposure prophylaxis (PrEP). In 2018, the FDA expanded the allowed use of the drug again. This time, the regulator accepted the use of Truvada to reduce the risk of HIV among adolescents.\nFDA Warnings About Truvada\nThe original insert warning informed users that cases of lactic acidosis and severe hepatomegaly with steatosis had been reported. In some cases, the use of Truvada had fatal consequences during testing. The warning also cautions users of the possibility of side effects, including:\nFat redistribution Immune reconstitution syndrome Lactic acidosis Hepatoxicity Flare-ups of Hepatitis B Changes in bone density, and Kidney problems\nThe warnings included in Truvada’s packaging were expanded by the FDA in 2012. This was due to the drug’s approval for the use as a PrEP drug. The new warning informed consumers that Truvada for PrEP was only intended for patients confirmed to be HIV-negative. The warning also suggests additional testing every three months. The FDA issued a strong warning against the use of PrEP for anyone that is HIV positive or unsure of their status.\nDovato\nReleased in early 2019, Dovato is the first two-drug complete regimen ever accepted by the FDA. Dovato contains dolutegravir and lamivudine, two drugs that have previously been used to treat HIV. The use of the drug is limited to patients who have never used antiretroviral treatments. It is also ineffective for anyone with a known resistance to either dolutegravir or lamivudine. Some doctors have voiced their skepticism about the drug given issues with resistance to the medication. There are additional concerns that the drug was approved despite the lack of long-term testing.\nFDA Recall of TDF Drugs\nDespite the serious medical issues linked to the use of Truvada and other HIV medications that contain TDF, the FDA has remained silent. To date, the regulator has declined to issue any form of recall or make a public statement. However, behind the scenes, the FDA has required some label changes to Truvada. Additionally, as discussed above, certain warnings have always been present on the Truvada package insert.\nContact Showard Law Firm\nThe research on the complications related to HIV medications is ongoing. However, given the reports of bone and kidney damage due to the use of TDF, our experienced HIV medications team is prepared to hold the pharmaceutical companies accountable. If you believe you have been injured by Truvada, Dovato, or other HIV medications, contact Showard Law Firm right away.\nAdditional Resources: FDA encourages additional Truvada research. https://www.fda.gov/news-events/fda-brief/fda-brief-fda-continues-encourage-ongoing-education-about-benefits-and-risks-associated-prep National Institute of Health. https://aidsinfo.nih.gov/understanding-hiv-aids/fact-sheets/21/58/fda-approved-hiv-medicines", "pred_label": "__label__POS", "pred_score_pos": 0.7466599941253662}
{"content": "WASHINGTON — Drivers with experience using advanced driver assistance systems such as adaptive cruise control and lane-keeping assist were nearly twice as likely to engage in distracted driving while using the systems compared to when they were driving without the systems, according to new research from AAA.\nAlternatively, drivers with less experience and familiarity using the technology were less likely to drive while distracted with systems activated compared to when systems were not in use, noted Dr. David Yang, executive director of the AAA Foundation for Traffic Safety.\n“This new research suggests that as drivers gain more experience using ADAS technology, they could develop complacency while behind the wheel,” Yang said. “Overreliance on these systems can put drivers and others in dangerous conditions during critical moments.”\nResearchers at the AAA Foundation collaborated with the Virginia Tech Transportation Institute to analyze video of on-road behaviors for two groups of drivers using advanced driver assistance technology. Individuals in one group owned a vehicle equipped with ADAS while drivers in the other group were given a vehicle equipped with ADAS to use during the four-week study period and had less experience with the technology.\n“Don’t get caught driving distracted when being focused on the road can save your life.”\nThe research found those drivers already familiar with the technology were more likely to drive distracted when these systems were active than when they were not. For example, some observed distracted driving behaviors included texting or adjusting the radio. Meanwhile, drivers with less experience using the technologies were more likely to remain attentive and engaged while the systems were engaged.\n“Advanced driver assistance technologies have a lot to offer in terms of comfort and safety, but they should never replace an attentive and engaged driver,” said Dr. William Van Tassel, AAA manager of driver training programs. “Remember, technology fails us daily while at work and at home. So, don’t get caught driving distracted when being focused on the road can save your life.”\nOriginally posted on Auto Dealer Today", "pred_label": "__label__POS", "pred_score_pos": 0.969890832901001}
{"content": "This study attempts to assess whether Sri Lanka has improved its competitiveness in both global and regional textile and clothing markets following the phasing-out of the Multi-Fibre Agreement (MFA) quota in 2005. It mirrors similar studies conducted across South Asian in four other countries. The study conducted by IPS evaluated strategies developed by firms in the industry to move up in global value chains, but also examined whether any potential exists for developing supply chains within the region.\nStrengthening the Textile and Clothing Industry in Sri Lanka Research team\nAshani Abayasekara\nChandana Karunaratne", "pred_label": "__label__POS", "pred_score_pos": 0.9999445080757141}
{"content": "This year's HIPAA settlements ran the monetary gamut and included the first ever fine levied due to untimely breach reporting. Here's an overview.\nWhile 2016 saw a dramatic uptick in the number of HIPAA-related settlements doled out by the U.S. Department of Health and Human Services (HHS) - including the largest settlement to-date - there were fewer cases overall in 2017. Despite this, the first ever settlement related to untimely reporting of a breach was issued this year and more than half of the fines landed in the multimillion dollar range, indicating that the improper disclosure of patients' protected health information (PHI) and electronic PHI (ePHI) remains a prominent and costly issue. Â Here are the details surrounding a few of the worst HIPAA-related settlements of 2017.", "pred_label": "__label__POS", "pred_score_pos": 0.999918520450592}
{"content": "Innovation is not about novelty; it is about creating value!\nWe can all be creative and innovative, as long as we take care to be:\n- Optimistic and open - Biaised towards action - Empathetic - Collaborative - Willingness to experiment - Iterative\nEverything we do more than once is a process. Innovating is no exception.\nUsing the Design Thinking methodology, we work through the steps:\nThe design team is equiped with a great toolbox. \"Brainstorming\" is usually the first to come to mind, but there is also:\n- Journey mapping - Prototyping - Visualization - Analogies - Ethnography - Personas - Storytelling - Mind mapping - Root cause analysis - Interviewing - Research - Learning launches - Minimum viable products - more...\nSuccessful innovation being the overlap of:\nWe are so taken by the design thinking methodology that we apply it to the wickedest problem of them all: life design.\nWorking off of the teachings of Bill Burnett and Dave Evans, we facilitate physical and virtual work groups in both french and english.", "pred_label": "__label__POS", "pred_score_pos": 0.5477989315986633}
{"content": "By Paolo Teotino\nThe latest Trellance M360 release, the most comprehensive update in the platform’s history, empowers organizations by digitally transforming their data into customized insights that accelerate business decisions. This comprehensive update offers new tools to boost customer engagement, elevates brand recognition, and saves community financial institutions time, energy and money.\nThese updates happen against the backdrop of unprecedented change and disruption that has forced community financial institutions to pivot frequently, build resiliency and adapt to rapidly accelerating changes daily. M360 now helps community financial institutions stay ahead in this world of constant change by offering more robust access to insights across the organization and scalable customized dashboards – delivering the connection and simplicity organizations crave.\nWith this powerful upgrade, the M360 platform further helps organizations take the risk out of decisions, minimize costs and deliver transformational business outcomes that set community financial institutions up for success – both during disruptive times and long after they’re over.\nLearn more about the latest M360 updates with our on-demand webinar, The New M360: Helping Credit Unions Connect with Their Members Through Data.\nIncreasing Access to Data\nTo further transform valuable data into actionable insights, M360 has added two new Loan Origination Systems (LOS) connectors to its already robust connector portfolio –Meridian Link LoansPQ and Finastra Fusion Mortgagebot.\nMeridian Link LoansPQis the industry’s leading consumer loan origination software, adopted by over 1,300 clients and used by 68 of the top 100 credit unions. The LoansPQ connector maps 311 new fields into M360. Finastra Fusion Mortgagebotis the leading mortgage loan origination software supporting retail wholesale and correspondent mortgage lending, with nearly 1,500 clients and 15% market share in the credit union industry. The Mortgagebot connector maps 245 new fields into M360.\nM360 customers can now benefit from a portfolio of ten pre-built integrations to the most popular cores and ancillaries’ software, unlocking key LOS insights such as loan pipeline metrics, loan lifecycle analysis, loan officer performance optimization, account/member profitability and more.\nBeyond the connector portfolio expansion, the M360 data model has expanded to leverage data generated from digital banking platforms – resulting in an addition of more than 400 data elements into the M360 common data model at the heart of the platform.\nImproving Insights and the Customer Experience\nAs community financial institutions face a new reality of rapidly evolving global markets and changing member behavior, it is vital they have visibility into multi-domain operations and deeper transactional insights. To accommodate, M360 has recently introduced a set of 19 new PowerBI data visualization dashboards mapping nearly 200 KPIs across many critical business domains such as finance, lending, product, member and application. To easily provide the most relevant data, these KPIs have been grouped into dashboards developed focusing on the needs of five executive profiles: CLOs, CFOs, CMOs, CXOs and CAOs.\nThese new dashboards, available to all our new and existing customers via direct download from an updated Trellance app store, generate benefits including:\nReducing the need to hire analytical resources to build and maintain custom reports. Reducing the “time to generate insights.” Increasing the ROI of the M360 investment by reducing the total cost of ownership. Creating an Ecosystem to Support Digital Transformations\nRecently, Trellance has refreshed its partnership programs to establish an ecosystem of certified software applications supporting the digital transformation journey of community financial institutions. This ambition’s guiding principle has been to help organizations reduce the complexity of integrating and managing distributed software requiring access to key core data while enabling credit unions to adopt new technologies and execute repeatable services efficiently.\nAs the M360 platform is already deeply integrated with credit unions’ core and ancillary systems, it represents the natural platform to deploy multiple vertical solutions. With the latest update, new partners will join the program:\nPrisma Campaigns:A marketing automation platform for financial institutions. Profit Resources:An insights organization that provides a web-enabled profitability dashboard that helps credit unions magnify the profit of their account holders, products, officers and branches. Flow Tracker Analytics: A tool that enables banking institutions to analyze money flow and make actionable insights accessible to marketing, sales and front-line staff.\nThanks to these new integrations, community financial institutions will be able to execute marketing campaigns or run profitability analysis that are automated, contextual, relevant and personalized. This not only delivers more value to members, but it also increases operational efficiency by making it easier to secure insights on member behavior via a seamless integration with Trellance M360 platform.\nSupercharging the Business Future\nWith this latest update, Trellance’s M360 platform solidifies its position as the market-leading analytics platform for community financial institutions looking to drive better business decisions through powerful data insights. As the world continues to evolve quickly, Trellance is already looking ahead to anticipate and solve new challenges in future updates with additional connectors, third-party data enrichment, predictive analytics and a cloud version of the M360 platform. These updates and continued support ensure that M360 remains a powerful and cutting-edge platform for organizations across the financial industry.\nLearn more about the latest M360 updates with our on-demand webinar, The New M360: Helping Credit Unions Connect with Their Members Through Data.", "pred_label": "__label__POS", "pred_score_pos": 0.9569832682609558}
{"content": "The Covid-19-pandemic will cause a global recession in 2020. In fact, the European Commission expects a decline of the Italian GDP by 9.5 %. The present report, which was written by the IER - Institute for Economic Research of the Chamber of Commerce of Bolzano in collaboration with EURAC Research, examines the impact of the emergency on the South Tyrolean economy and presents firms’ first reactions to the crisis.", "pred_label": "__label__POS", "pred_score_pos": 0.9891130924224854}
{"content": "The discontinuation of oral oncology medications before the full-month supply has been finished results in medication waste, leading to increased costs for patients and for payers. Split fills allow for a 14- to 16-day supply for oral oncology medications rather than a full 28- to 30-day supply. Researchers compared the discontinuation rates, patient-reported adverse events, estimated pharmacy costs, and potential waste in patients with pharmacy benefit designs that included a split-fill option with patients who did not have this option (Staskon FC, et al. J Oncol Pract. 2019;15:e856-e862).\nThis retrospective cohort study included patients who were new to therapy with one of the 11 split-fill oncology oral medications within the managed program, between September 2015 and August 2017. Patients using split-fill and non–split-fill medications were matched by age, sex, state census areas, index medication, start date, and the use of >1 medication. The study included 2363 patients within the managed program who met the selection criteria for the 11 medications, and 671 patients from each group were matched.\nThe per-month medication discontinuation rates were assessed for each group. The monthly utilization trends indicated a significantly higher persistency rate for the split-fill cohort than the non–split-fill cohort in the second month (71.6% vs 67%, respectively; P <.001). Payers participating in a split-fill program had mean average wholesale price (AWP) savings of $2147.60 at 1 month and $928.60 at 6 months. Based on modeled waste, payers without a split-fill program could expect to save $2646.74 AWP monthly if they moved to the split-fill option.\nBoth cohorts had similar rates of adverse effects (55.3% for the split-fill cohort vs 56.4% for the non–split-fill cohort). The time until the first reported adverse effect trended toward being earlier for the split-fill group, but not significantly earlier.\n“Even after noted modifications were made for new therapies, the split-fill patient managed component had lower discontinuation rates, significantly reduced pharmacy costs, and reduced potential wastage,” concluded the researchers. “By adopting a split-fill option, insurance payers have a means of reducing the pharmacy cost for new oncolytic therapy drugs, providing additional benefits to patients regarding copay, and addressing adverse events.”\nStay up to date with oncology news & updates by subscribing to recieve the free OPM print publications or weekly e‑Newsletter.\nSubscribe to recieve the free, monthly OPM print publication and OPM weekly e‑newsletter.", "pred_label": "__label__POS", "pred_score_pos": 0.9661881327629089}
{"content": "Forex trend strength refers to the likelihood of an emerging trend to come to fruition, persist, or dictate movements in the\nforeign exchange market. Traders new and old are aware of the importance of trends, but not many pay attention to the strengths of such trends. To gauge trend strength and make more informed trade decisions that lead to success, it would help to consider the following techniques. High and Low Monitoring\nMany analysts believe that the highs and lows on a chart tell the whole story. The relationship between these high and low points as they form over time can help predict the next trends. This technique is primarily about observing where the extended swing highs and lows are within a given trend.\nWith high and low monitoring, the key to determining the\nstrength of a trend is finding the signs that a trend is about to start reversing. For example, a chart for a particular period shows a trend of ascension if the highs continue going higher while the lows are not going lower. Generally, this trend is only deemed to be reversing if the highs start dropping along with the lows.\nThe trend will not always be obvious, but it is not that difficult to spot the points when the highs stop climbing up and the lows start descending. If the trend appears too fuzzy, it helps to compare the highs and lows with a key level that offers a favorable picture. Doing so will make it easier to see the extent of the trend and when it will likely reverse.\nAverage Directional Index (ADX)\nThe ADX is a basic tool used in determining when a price is trending strongly. It quantifies trend strength based on a moving average of price range increases in a given period. It is applicable to various traded assets including mutual funds, stocks, and futures. An ADX value in the 0-25 range is described as absent or weak. The 25-50 range is considered strong. Meanwhile, ADX values in the 50-75 and 75-100 brackets are regarded as very strong and extremely strong respectively.\nSome forex traders may not pay attention to ADX because it does not exactly indicate when to buy or sell. However, it can actually be used in forex trading especially in MT4, the trading platform used by many online speculative traders like\nGainsky, eToro, and Zulutrade.\nMT4 features an advanced ADX function that utilizes tweaked auto-smoothing techniques to come up with a graph that is more precise but not as smooth as usual. Together with the MACD indicator, ADX values can be used not only to determine trend strength but also to make a buy or sell decision.\nSubsequent Retest Distance Tracking\nA retest refers to the reversal of the price direction after a break and returns to the breakout level. In other words, the highs continue going up in an upward trend while the lows keep going down in a downward trend.\nSubsequent retest distance tracking means observing the distances between the lows and the reversal points, starting from the subsequent retest instance. If this distance continues to decrease, the conclusion is that the trend is weakening. A trend reversal is already imminent. Hence, the logical reaction is to tweak plans to trade in the direction of the strong trend to reduce risks.\nClustering Price Action\nThis technique can be considered as a combination of high-low monitoring and retest distance tracking. Its focus is on the point when the market starts to exert constant pressure on a key level over a short duration.\nTo determine trend strength through clustering price action, it’s crucial to watch out for market responses to support or resistance within a given period, which may be a few days to an entire week. If the market starts to group together for an extended time at a key level, it can be said that the trend is already disintegrating, headed for a reversal.\nGainsky Investment is a forex shared trading platform that offers different asset trading such as forex and cryptocurrency. Determining the strength of a trend is crucial in forex trading as it subjects probabilities into more discernible success-loss probabilities. By trading with a strong trend, the chances of yielding a profit increase. It becomes easier to make a decision as compared to viewing graphs and data with a much broader perspective. Gainsky can help to provide a solution if you are facing any problem. Image: Pexels", "pred_label": "__label__POS", "pred_score_pos": 0.581670880317688}
{"content": "Teachers have long been identified as the number one in-school factor that influences student outcomes. Conversely, teacher turnover is correlated with lower student outcomes and contributes to school cultures where churn and instability prevent positive change from taking root. How to retain teachers has emerged as a key area of interest for district leaders and policymakers.\nIn Core Education’s June issue brief, we explore the problems associated with teacher turnover, look at the reasons teachers themselves give for leaving the profession, and examine strategies for increasing retention of effective educators, including teacher mental health, administrative support, professional learning and school climate.\nTo access the issue brief, visit: https://mailchi.mp/a17cbcb5fa5a/7y14uz9cvv-1824961\nTo ensure you do not miss future monthly briefs, subscribe here: http://eepurl.com/G1ciT", "pred_label": "__label__POS", "pred_score_pos": 0.9807536005973816}
{"content": "A mandate is a contract by which a person, the mandator, gives power to another person, the mandatary, to represent him. This contract is called a power of attorney.\nAlzheimer’s\nAlzheimer’s lasts for many years, during which time behaviors and abilities change as the disease progresses\nThe following has been reprinted with permission from the Association for Psychological Science. Older adults are often encouraged to stay active and engaged to keep…\nAn Israeli study has discovered a biological mechanism that could explain how challenging mental and physical activity can delay the development and onset of Alzheimer’s…\nI recently attended the 2014 Canadian Conference on Dementia in Vancouver. The focus of the conference was a “person-centred approach to dementia care.” Research presented…", "pred_label": "__label__POS", "pred_score_pos": 0.740404486656189}
{"content": "Our Abuja reporter│ 17 July 2020 │ 10:00\nBeginning on August 1, 2020, banks in Nigeria will have the power to debit loans and accrued interests due from bank accounts of loan defaulters across the Nigerian banking system.\nThe Central Bank of Nigeria (CBN), on July 14 issued a new guideline to this effect, implying the seizure of debtors’ fund across the banks. The Apex bank has once again reinforced its commitment to strengthening the financial services sector.\nAccording to a circular issued by the CBN Director, Financial Policy and Regulation Department, Kevin Amugo, this initiative aims to improve the credit repayment system, reduce non-performing loans in the banking system and watch-list consistent loan defaulters.\nThis operational guideline is tagged ‘Global Standing Instruction’ (GSI). The Nigeria Inter-Bank Settlement System Plc (NIBSS) will manage the entire operations of the GSI on behalf of banks, using customers Bank Verification Numbers (BVN).\nThis initiative, which has been underway since May 2019, is based on a prolonged series of agreements involving the CBN, NIBSS and the Bankers’ Committee.", "pred_label": "__label__POS", "pred_score_pos": 0.9741949439048767}
{"content": "Miranda, A., Pego, J. M., Correia-Pinto, J. 2017. Animal facility videoendoscopic intubation station: Tips and tricks from mice to rabbits. Laboratory Animals 51(2), 204-207.\nEndotracheal intubation of laboratory animals is a common procedure shared by several research fields for different purposes, such as mechanical ventilation of anaesthetized animals, instillation of cytotoxic nanoparticles, infectious agents or tumour cells for induction of disease models, and even for diagnostic and therapeutic purposes. These different research purposes, achieved in different animal models, require technical expertise and equipment that suits every research need from animal facilities. In this short report we propose a videoendoscopic intubation station that could be shared among the most common laboratory animals, namely the mouse, rat, guinea pig and rabbit, from neonates to adult animals. This report aims to contribute to the reduction of animals excluded from experiments due to false paths during direct and blind intubations and to the refinement of procedures by replacing surgical approaches such as tracheotomy.", "pred_label": "__label__POS", "pred_score_pos": 0.9574353694915771}
{"content": "At Kristus Darzs we practice person-centered care approach.\nWe involve residents and their families in care planning alongside health care professionals. Our nurses and personal support workers strive to provide exceptional care honouring individual values, preferences and lifestyles while maintaining the dignity and rights of each resident. Nursing staff make every effort to meet the residents’ physical, emotional and social needs by working collaboratively with other departments, medical doctors and specialists.\nNursing care is provided 24 hours a day 7 days a week.\nOur staff assist residents in performing all activities of daily living including personal hygiene, grooming, dressing, eating, toileting, transferring and mobility. Staff are mindful of the physical and psychological abilities of the individual. Residents are encouraged to use their abilities to their full potential to maintain their skills and independence for as long as possible.\nThe majority of our residents are living with dementia. Dementia care requires additional knowledge and specialized skills in providing individualized care with kindness, patience and respect. Working in collaboration with other departments, nursing staff employ their expertise to creatively and effectively manage responsive behaviours. When necessary, we seek guidance from external agencies specializing in behaviour management or through Geriatric Psychiatrist referral.\nIn recent years, we have made several updates to our physical environment. The distinct wall colours make way-finding easier for residents with dementia. The dining room murals depicting Riga and the much-loved birches and fields of Latvia provide calm space where residents can reminisce and feel peaceful. Our staff are provided with opportunities for professional growth and development fostering pride and personal satisfaction.\nKristus Darzs is committed to lifelong learning by encouraging pursuit of professional degrees, designations or certificates within the healthcare field. Staff are encouraged and regularly complete continuing education to enhance evidence informed knowledge within specific areas of interest, such as wound care, responsive behaviours, and continence management.", "pred_label": "__label__POS", "pred_score_pos": 0.9450215697288513}
{"content": "Abstract\n© 2015 Elsevier B.V. Submarine groundwater discharge (SGD) was investigated at El Gorguel Bay (Cartagena-La Unión Pb-Zn mining district, Murcia, Spain), a Mediterranean region where mine tailings have been accumulated for decades at the shoreline. At this site, groundwater may become enriched in metals prior to discharge to the coastal sea and may lead to significant releases that can contaminate the coastal environment. The distribution of dissolved metals and Ra isotopes were studied in seawater and groundwater samples collected during the summer season in 2013. Cross-shore gradients of 224Ra in the bay allowed the calculation of a SGD flow of (39±14)103m3day-1. SGD-driven metal fluxes were 47-180molday-1km-1 for Zn, 0.20-0.60molday-1km-1 for Pb, 4-32molday-1km-1 for Fe, 0.8-2.3molday-1km-1 for Cu and 0.9-2.8molday-1km-1 for Ni. Compared to other coastal zones not affected by mining activities, SGD-driven metal fluxes were especially significant for dissolved Zn and Pb. The magnitude of these SGD-driven metal fluxes indicates that SGD is a relevant pathway in delivering metals to the coastal environment at El Gorguel Bay. This fact highlights the importance of investigating the role of SGD as a possible source of contamination to the sea in mining districts located in the proximity of the coast.\nKeywords Lead Metals Mine tailings Radium isotopes Submarine groundwater discharge (SGD) Zinc", "pred_label": "__label__POS", "pred_score_pos": 0.7628393769264221}
{"content": "Attachments HIGHLIGHTS\nIn response to displacement from Ramadi, UNHCR provided emergency shelter for 1,440 displaced people in Al Qaser camp, in Habbaniyah Tourist City (HTC). Displaced families sheltering in various locations in HTC and Ameriyat al Falluja also received winter assistance kits and kerosene to meet their domestic needs.\nUNHCR continued to deliver essential assistance to help the displaced families cope with harsh winter temperatures. UNHCR is distributing winter household items to 60,000 vulnerable displaced families this winter.\nUPDATE ON ACHIEVEMENTS Operational Context\nAccording to IOM’s Displacement Tracking Matrix (DTM), the estimated number of internally displaced Iraqis now exceeds 3.19 million, spread across more than 3,500 locations countrywide.\nConflict and violence continue to affect most of Central and North-Central Iraq, including Anbar, Ninewa, Salah al Din and Kirkuk governorates.\nDisplacement continued throughout Anbar, Kirkuk, Ninewa and Salah al Din governorates. Access to safety for IDPs continues to be a challenge across Iraq. Access to many of Iraq’s governorates remains contingent upon sponsorship and many families cannot cross checkpoints and remain stuck at governorate borders. The inability of civilians to access safety is a major protection concern, both on account of being prevented from fleeing areas under the control of armed groups or due to restrictions imposed by authorities.\nAn estimated 4,000 people were newly displaced following military operations to regain control of Ramadi, Anbar Governorate’s capital, from armed insurgents. Displaced families are living in various camps established by local authorities in Habbaniyah Tourist City and Ameriyat al Falluja, which are now at full capacity. Expansions are planned to accommodate more displaced Iraqis.\nThe city of Falluja has been under siege due to ongoing military operation and supply lines have been cut off. Residents in the city are reportedly facing an acute lack of fuel, as well as basic necessities, clean water and medicine.\nAs of end January, IOM’s Displacement Tracking Matrix identified more than 485,000 people who have returned to their areas of origin in Anbar, Diyala, Erbil, Kirkuk, Ninewa and Salah al Din governorates. Returnee families remain vulnerable as they face a lack of livelihood opportunities, destruction of property, contamination by explosive remnants of the conflict, limited availability of food and non-food items, documentation problems as well as poor access to services, health, clean water and education. UNHCR and the UN humanitarian country team do not encourage organized returns of IDPs in view of the continued absence in many locations of protection conditions conducive to return. However, support is provided to spontaneous IDP returnees whenever it is safe to do so.\nTemperatures continued to drop across Iraq as winter set in, with displaced families living in tents and unfinished building struggling to cope with heavy rains and cold. This is particularly challenging in the mountainous areas of Duhok and Sulaymaniyah in the KR-I, where the conditions remained challenging for the displaced, despite the assistance given by the international community.", "pred_label": "__label__POS", "pred_score_pos": 0.6884191036224365}
{"content": "Abstract\nChemical vapour deposition of graphene was the preferred way to synthesize graphene for multiple applications. However, several problems related to transfer processes, such as wrinkles, cleanness and scratches, have limited its application at the industrial scale. Intense research was triggered into developing alternative synthesis methods to directly deposit graphene on insulators at low cost with high uniformity and large area. In this work, we demonstrate a new concept to directly achieve growth of graphene on non-metal substrates. By exposing an amorphous carbon (a-C) film in Cu gaseous molecules after annealing at 850°C, the carbon (a-C) film surprisingly undergoes a noticeable transformation to crystalline graphene. Furthermore, the thickness of graphene could be controlled, depending on the thickness of the pre-deposited a-C film. The transformation mechanism was investigated and explained in detail. This approach enables development of a one-step process to fabricate electrical devices made of all carbon material, highlighting the uniqueness of the novel approach for developing graphene electronic devices. Interestingly, the carbon electrodes made directly on the graphene layer by our approach offer a good ohmic contact compared with the Schottky barriers usually observed on graphene devices using metals as electrodes.\nAll Science Journal Classification (ASJC) codes Materials Science(all)", "pred_label": "__label__POS", "pred_score_pos": 0.5421711206436157}
{"content": "Los Angeles County is home to 10 million people and hundreds of cities, communities, and neighborhoods. Los Angeles is also known as one of the most ethnically diverse counties in the United States, which is reflected in its many cultural enclaves and communities.\nThe earliest of Los Angeles enclaves include Chinatown, Frenchtown, Greek Town, Little Italy, Little Tokyo, and Sonoratown. Only Chinatown and Little Tokyo exist today. The second wave of ethnic enclaves in Los Angeles began following the 1968 enactment of the Immigration and Nationality Act of 1965. It ended an immigration-admissions policy based on race and ethnicity, and gave rise to large-scale immigration, both legal and unauthorized. The enclaves are products of both historical racial discrimination and self-segregation driven by mutual, ethnically specific interests. Ethnic enclaves provide protection from hostile elements in society, aid in the retention of cultural norms (including language), and offer immigrants economic opportunities such as employment and business ownership. One of the communities featured in the exhibit include the city of Watts and its famous Watts Towers. The artist Simon Rodia titled the structural art piece, “Nuestro Pueblo,” meaning “Our Town.” Los Angeles has myriad communities including LGBTQ, activist groups, campus communities, and women’s groups. These diverse communities and cultural enclaves that make up Los Angeles have a long history striving for acceptance, equality, and empowerment. Explore the items on display to catch a glimpse of the significant events and communities of Los Angeles.", "pred_label": "__label__POS", "pred_score_pos": 0.5271217823028564}
{"content": "Cultural Heritage Expert (2018)\nThe Government of Indonesia contracted with the World Bank and Tourism Development International (TDI) to develop an Integrated Tourism Master Plan (ITMP) for Yogyakarta, Borobudur and Prambanan in Central Java. The plan provides a strong framework for effective and sustainable tourism and land development.\nAs the Cultural Heritage Expert, I researched and inventoried all sites in the region to ensure that planned developments are sustainable and comply with international standards for heritage preservation.\nBorobudur (9th Century Buddhist) and Prambanan (9th Century Hindu) temples are both cultural heritage sites of global significance and were inscribed onto the UNESCO World Heritage List in 1991. However, they are in danger of losing their outstanding universal values due to over visitation, mismanagement, and an overall lack of understanding and awareness of the importance of preserving the country's tangible and intangible heritage resources. It is hoped the ITMP will mitigate some of these negative effects.\nYogyakarta is the center of the country's hand painted batik fabrics. Indonesian Batik was inscribed onto the UNESCO Intangible World Heritage List in 2009.", "pred_label": "__label__POS", "pred_score_pos": 0.566724419593811}
{"content": "Abstract\nMassive rural–urban migration in China has drawn attention to the prevalence of mental health problems among migrants. Research on the mental health of Chinese migrants has a narrow focus on rural–urban migrants, emphasizing the institutional role of hukou in migrant mental health. We argue that the heterogeneity of migrants, including", "pred_label": "__label__POS", "pred_score_pos": 0.9465855360031128}
{"content": "Abstract\nResearch on emotion technology in artificial intelligence is taking off, but there has been less attention on the possible applications of emotions and emotional intelligence in artificially intelligent systems. Reviewing contemporary literature, this thesis provides a comprehensive overview of emotion in humans, affective computing and modern emotion technologies. Additionally, recent", "pred_label": "__label__POS", "pred_score_pos": 0.8789334297180176}
{"content": "At the point when individuals plan to offer a home, the greater part of them work hard to make their house is as alluring as could be allowed. This could incorporate pretty much anything, from re-painting dividers to making minor repairs to enlisting a home organizing expert. In a purchasers showcase like this, venders work hard at making their home shimmer. They could never associate that all with these enhancements could be totally refuted by the family canine.\nFor property holders with pets, offering a house could require some additional exertion. Pets desert proof of their quality, regardless of whether it be as scratch marks, hair, scents, or more. This can represent an issue for potential home purchasers which may have hypersensitivities. There could be security issues for pets and individuals alike, as there truly is no real way to know how a creature will respond with unusual individuals in the house. Moreover, a few people are so emphatically opposed to pets they will decline to consider a home where they have dwelled as of late. Fortunately, there are steps a mortgage holder can take with a specific end goal to guarantee that the family pet doesn’t drag out the offer of a house or more terrible, adversely affect its cost.\nThe main answer for be considered is to move the pet to Sunroom Addition Guys else if conceivable. This could be a companion or relative willing to deal with the hairy little person or it could include boarding the creature. Having the them out of the family unit would be the simplest, best approach to keep a pet’s essence from meddling with the offer of a home. The disadvantage is homes are spending longer available nowadays and boarding a pet for a considerable length of time would not just get costly, it would be savage.\nIn the event that boarding the creature outside of the house is impossible, check whether its conceivable mastermind companions or family to take the pets for a couple of hours amid showings. Having them at the house is the last decision and ought to be kept away from no matter what. If so, they ought to be limited in a pet hotel or outside. Not exclusively are yapping canines and underneath felines diverting, if a potential home purchaser is chomped, they won’t buy the home and they may document a claim to boot.", "pred_label": "__label__POS", "pred_score_pos": 0.796367883682251}
{"content": "Anyone who has spent time around children knows they love to wonder, “Why?” By using history mysteries in our lessons, we can turn the questions of “Why?” and “How?” back onto students to engage them fully. Continue reading Strategy Share: Using History Mysteries to Engage Students\nI have been fascinated with the Galápagos Islands since reading Darwin’s On the Origin of Species as a college student. When I had the opportunity to explore the islands as a Grosvenor Teacher Fellow, I naturally thought I would design a student project focused on evolution. However, observations I made while in Galápagos led me down a different path. Continue reading Strategy Share: Conservation Lessons From Galápagos", "pred_label": "__label__POS", "pred_score_pos": 0.9687715768814087}
{"content": "Computational models provide a framework for integrating data across spatial scales and for exploring hypotheses about the biological mechanisms underlying neuronal and network dynamics. However, as models increase in complexity, additional barriers emerge to the creation, exchange, and re-use of models. Successful projects have created standards for describing complex models in neuroscience and provide open source tools to address these issues. This lecture provides an overview of these projects and make a case for expanded use of resources in support of reproducibility and validation of models against experimental data.\nIntroduction to the Brain Imaging Data Structure (BIDS): a standard for organizing human neuroimaging datasets. This lecture was part of the 2018 Neurohackademy, a 2-week hands-on summer institute in neuroimaging and data science held at the University of Washington eScience Institute.\nNWB: An ecosystem for neurophysiology data standardization\nNWB: An ecosystem for neurophysiology data standardization\nThis lecture provides an overview of depression (epidemiology and course of the disorder), clinical presentation, somatic co-morbidity, and treatment options.\nThis lecture will highlight our current understanding and recent developments in the field of neurodegenerative disease research, as well as the future of diagnostics and treatment of neurodegenerative diseases\nHow genetics can contribute to our understanding of psychiatric phenotypes.", "pred_label": "__label__POS", "pred_score_pos": 0.7521144151687622}
{"content": "A new study conducted by the Association for Professionals in Infection Control and Epidemiology (APIC) finds that while steps to stop the spread of the intestinal superbug Clostridium difficile-often called C. diff infection or CDI-have increased, they are not yielding significant improvements.\nAccording to the survey of 1,087 APIC members conducted earlier this year, 70 percent have adopted additional intervention measures to counter CDI since March 2010, but only 42 percent have seen a decline in CDI rates in their healthcare facilities; 43 percent report no decline at all.\nCDI can cause symptoms ranging from diarrhea to life-threatening inflammation of the colon, and it kills about 14,000 Americans each year. It most commonly affects older adults in hospitals or in long-term-care facilities.\nWhile the researchers were encouraged by the fact that more efforts are being undertaken to prevent CDI, \"more needs to be done to reduce the spread of this disease,\" says Jennie Mayfield, APIC president-elect.\n\"Environmental Services [referring to cleaning and housekeeping services] must take the lead in developing aggressive programs [and] cleaning practices...and ensure that the results are shared with front-line staff. Without this, [conditions] are unlikely to improve.\"\nThe report did not specifically mention what types of \"aggressive programs and cleaning practices\" might be necessary, but because current cleaning practices are not having the desired results, some experts suggest new or alternative cleaning methodologies may now be called for.\nFor instance, some healthcare facilities are replacing conventional cleaning methods-cleaning cloths, mops, and buckets-with spray-and-vac or \"no-touch\" cleaning systems.\nDr. Jay Glasel, founder of Global Scientific Consulting, LLC, in Farmington, Connecticut, reports that these systems can be as much as \"60 times more effective at reducing bacterial contamination when compared to conventional cleaning methods.\"\nAll the more reason to look into cleaning alternatives, according to the Centers for Disease Control and Prevention, deaths related to CDI are increasing, due in part to a stronger germ strain.", "pred_label": "__label__POS", "pred_score_pos": 0.6482580900192261}
{"content": "Aided by rock-bottom interest rates, the U.S. housing market reached a new milestone: total American mortgage debt hit a record high of $9.86 trillion in the third quarter, according to the Federal Reserve Bank of New York. The total value of new mortgages, including home purchase loans and refinances, rose to $1.05 trillion. While the debt load is higher than ever, the silver lining is that the share of borrowers with credit scores above 760 is also at its peak.", "pred_label": "__label__POS", "pred_score_pos": 0.8768109083175659}
{"content": "Practical supports that impact day to day living for people living with HIV/AIDS are a core outcome of many PWA services, and we specifically highlight financial assistance and food within the practical supports category.\nFinancial Assistance We reimburse people for the purchase of uninsured prescription medication, supplementary treatment costs and nutritional supplements. This program also offers a stipend to individuals applying for Ontario Disability Support Program (ODSP), individuals 64 and older and 17 and younger. The program and criteria is reviewed annually. Review the latest Guidelines for the most up-to-date coverage.\nWe partially reimburse people for the purchase of expenses such as:\nUninsured prescription medication, Supplementary treatment costs, Nutritional supplements, Emergency veterinarian, Transportation\nThe Program is available to all PWA Clients on a limited basis. For more information, you can review our 2020/2021 Financial Assistance Guidelines or speak to your Income & Community Liaison.\nEssentials Market This is PWA’s food bank which provides staple food items, fresh produce from our community garden, pet food, home start-up items, family hampers, special needs supplies such as baby items, and special diet accommodations based on availability. The PWA Food Bank is the only food bank in Toronto that exclusively serves people living with HIV / AIDS. Participants can access the market twice a month, Wednesdays and Thursdays from 2pm to 7pm. ID is required\nIf you have any questions about this program, contact the Food Programs Coordinator.\nCommunity Food For Life Program\nThis community program is in partnership with Dixon Hall Neighborhood Services, it is a weekly frozen meal delivery program for PHAs returning home from the hospital, experiencing severe mobility, acute medical issues, or are receiving palliative care.\nIf you have any questions about this program, contact the Food Access Liaison.\nVitamin Supplements Based on availability, vitamins are also provided.\nPWA would like to thank the Village Pharmacy for their generous donation of Vitamin Supplements for this program. Their dedication to helping people living with HIV/AIDS is deeply appreciated.", "pred_label": "__label__POS", "pred_score_pos": 0.8951544761657715}
{"content": "The paper explores the rural-urban axis in post-socialist Macedonian views of the past, present and future. Social tensions in the Balkans, and the former Yugoslav republics in particular, are often viewed as a direct product of interethnic hostilities. Focusing in particular on Macedonian responses to domestic unrest since 1991, this paper traces the importance of crime, gender roles and mobility as key concerns in the post-Yugoslav context. It offers a complementary interpretation of anti-Albanian discourse, which highlights the enduring significance of the rural-urban distinction in contemporary Macedonia.", "pred_label": "__label__POS", "pred_score_pos": 1.000009298324585}
{"content": "Data integrity refers to maintaining and assuring the accuracy and consistency of data over its entire life-cycle, and is a critical aspect to the design, implementation and usage of any system which stores, processes, or retrieves data. The term data integrity is broad in scope and may have widely different meanings depending on the specific context– even under the same general umbrella of computing. This article provides only a broad overview of some of the different types and concerns of data integrity.\nData integrity is the opposite of data corruption, which is a form of data loss. The overall intent of any data integrity technique is the same: ensure data is recorded exactly as intended (such as a database correctly rejecting mutually exclusive possibilities,) and upon later retrieval, ensure the data is the same as it was when it was originally recorded. In short, data integrity aims to prevent unintentional changes to information. Data integrity is not to be confused with data security, the discipline of protecting data from unauthorized parties.", "pred_label": "__label__POS", "pred_score_pos": 0.917256772518158}
{"content": "Making the decision to place an elderly loved one in a nursing home or assisted living center is often fraught with guilt and worry. That’s understandable, since one-third of the residents and patients in skilled nursing facilities experience harm like infections and medication errors related to their treatment.\nIn one independent review of patient records, physicians found 59 percent of the injuries and errors were preventable. Over 50 percent of those patients who suffered harm were readmitted to hospitals as a result.\nThe inspector general for the U.S. Department of Health and Human Services (HHS) conducted a research study focusing on the quality of skilled nursing care. They followed patients for as long as 35 days after their discharge from acute care hospitals.\nThese doctors discovered that 22 percent of the discharged patients suffered adverse events causing lasting harm, with 11 percent suffering temporary harm. Sadly, 1.5 percent of patients succumbed due to the poor care they received even though their physicians had not anticipated their demise.\nThese deaths and injuries resulted from inadequate monitoring, delays, substandard treatment and failing to provide necessary treatment. The fatalities resulted from preventable issues that included:\nkidney failure blood clots excessive bleeding from anticoagulant drugs fluid imbalances\nIf your loved one is in a skilled nursing facility, you often have to take on the role of patient advocate if they are no longer able to advocate for themselves. If you see or suspect signs of abuse, neglect or other red flags, you might need to take legal action against the facility, its owners and managers, and the doctors and nurses providing substandard care.", "pred_label": "__label__POS", "pred_score_pos": 0.6342564821243286}
{"content": "Strategy 2021+ builds on the strong foundation of continuous performance to deliver sustainable value creation and attractive shareholder returns. Leveraging its Romanian skills and expertise, OMV Petrom is committed to maintain and strengthen its position as a leading energy player in the region, ensuring its long-term growth, focusing on opportunities that Romania still offers while enhancing customer experience and developing its portfolio through regional expansion.\nThe strategy is driving performance through three key pillars:\nEnhancing competitiveness in the existing portfolio Developing growth options Regional expansion\nWith a clearly defined execution plan, the strategy is addressing the sustainability of the reserve base, targeting the maximization of operational efficiency and exploring opportunities along the value chain, preparing the company for new developments in the energy sector. Strategy implementation ensures improved profitability while maintaining a strong balance sheet and offering attractive shareholder returns.\nThe success of the strategy is fueled by three enablers:\nPeople and Organizational Culture Sustainability Technology and Innovation\nFor more details please see the attached\n\"Strategy 2021+\" presentation. Disclaimer:\nThe information herein represents the strategic directions of OMV Petrom and may be interpreted as forward looking statements subject to uncertainties, risks and regulatory changes which may cause the actual results/performance of OMV Petrom to be materially different. Under no circumstances may be deemed as representation/warranties of OMV Petrom or of its management regarding the company’s’ future results as well as a recommendation/ offer / invitation to subscribe for or purchase any securities. Contact: corporatestrategy@petrom.com", "pred_label": "__label__POS", "pred_score_pos": 0.9598040580749512}
{"content": "Following the release of latest newsletter, by the Financial Conduct Authority, Market Watch 64 directed towards MiFIDii Firms signaling the preparation for the end of the Brexit transition period, Point Nine is offering a helping hand.\n” The temporary transitional power aims to minimise disruption for firms and other regulated entities at the end of the transition period. It allows firms time to adapt to new requirements from Brexit. But in some areas, applying the power would not be appropriate. One of these areas is transaction reporting rules under MiFID II. It is crucial that we receive these reports to ensure market oversight and the integrity of financial markets. So, firms and Approved Reporting Mechanisms should comply with the changes to their regulatory obligations by the end of the transition period on 31 December 2020. Firms that are not able to comply fully with the regime immediately following the end of the transition period will need to be able to back-report missing, incomplete or inaccurate transaction reports as soon as possible.” Market Watch 64, FCA – August 2020.\nIf you are unsure how Brexit will impact your reporting obligations, Point Nine can help you navigate.\nFor further details on Brexit reporting implementation or support for meeting the deadline for your regulatory obligations by end of the transition period. In case of difficulty meeting the end of transition deadline (31 December 2020) Point Nine is equipped and ready to seamlessly support with back-reporting, quality assurance, reconciliation, and governance. Contact us", "pred_label": "__label__POS", "pred_score_pos": 0.8286804556846619}
{"content": "Our Philosophy\nA dog-lead training process.\nA dog-led Training Process\nWe believe that clear communication and biological fulfillment lead to a confident state of mind. The goal being: training for a dog that makes choices and decisions that align with its owner’s agenda and lifestyle.\nIt's a dog-led process, in that we have to have patience, awareness, and consideration for your dog, their feelings, and how they are expressing themselves. Emotions are instinct, and rather than suppress our dog's emotional responses to the world, we support the dog through their emotional responses, and guide them to the desired behavior. The ultimate goal of this approach is to foster a calm dog with a positive outlook on the world:\nUsing clear communication and biological fulfillment to develop and nurture a calm, neutral dog.\nMoving training beyond obedience and management to focusing on a dog’s state of mind and outlook on the world.\nCombining Animal Behavior science, dog psychology, and neuroscience, to form the emotions-based training philosophy.\nBy rewarding your dog's choices that are in alignment with your agenda, you prime them to think, act, and feel like the dog you want them to be in the future.\nTraining for your dog and your lifestyle\nDo you want a dog who:\nWill come when you call no matter what the distraction is?\nIs in a healthy state of emotional stability in all of their interactions with the world?\nMakes good choices and stays out of trouble, even when you aren't around?\nEnds each day feeling happy, satisfied, and biologically fulfilled.", "pred_label": "__label__POS", "pred_score_pos": 0.6536962985992432}
{"content": "Last updated on 23-8-2019 by Anonymous (niet gecontroleerd)\nAuteursMarie-Alice Fraiture Trefwoorden Samenvatting:\nTo guarantee the traceability on the market and the freedom of choice for consumers, genetically modified organisms (GMO) legislations have been established in many countries, including in Europe (EU). However, the implementation of these legislations by the enforcement laboratories is becoming complex due mainly to the increasing number and diversity of GMO. To cope with the problematic of EU unauthorized GMO, this PhD aims to improve and strengthen the existing GMO detection system using high-tech approaches. First, as a study case, an overview of genetically modified (GM) rice, de…", "pred_label": "__label__POS", "pred_score_pos": 0.8842529058456421}
{"content": "Improve your personal protective equipment stash or add to your regular business wear with these face masks and respirators. These masks are small enough to keep multiples stored without wasting storage space. Some masks such as N95 masks provide ample protection from small particles to protect your respiratory system.\nDisposable\nMany of these face masks are disposable, so you can use them for protection on rough days and toss them in the trash. Make cleanup a breeze with a disposable option that takes up little room in comparison to larger, reusable options. For businesses that rarely need respirators or face masks, low-cost disposable options are ideal.\nReusable\nSome models are reusable, including some N95 masks, though the internal filter typically needs to be replaced. These allow you to change the filter to better match the particles in the air you are trying to avoid. Keep these in stock next to ear plugs\nand other personal protective equipment for a fully stocked supply cabinet that protects you and your employees.\nComfortable\nMasks and respirators typically have many comfort features, including a molded nose bridge or a bendable bridge for the best fit. A secure seal around the top of the mask reduces fog on glasses for safety and comfort. Most models feature multiple straps for added comfort and adjustment options that can fit a range of users.\nBreathing Valve\nOpt for a face mask or respirator that has a cool flow exhalation valve for the most comfort when breathing, like certain N95 masks. This allows air to move out of the mask during exhalation, reducing heat and moisture as you work. These valves also ensure you get fresh air with each inhalation.", "pred_label": "__label__POS", "pred_score_pos": 0.7480391263961792}
{"content": "Share This Post:\nDuring these unprecedented times of the spread of COVID-19, social distancing has become the new norm and businesses have turned to remote working. But what happens to processes like appraisals which involve in-house evaluations? In a recent webinar hosted by the Florida Association of Mortgage Professionals, leadership from the National Appraisal Network (NAN) explained in-depth the impact of COVID-19 on appraisals.\nFirst and foremost, all appraisals nationwide should start traditionally. In the case that a traditional appraisal is not possible, due to a lock-down or a homeowner not wanting anyone in the home, Fannie, Freddie, HUD, USDA, and others are offering alternative appraisals. Alternative appraisals can either be a desktop appraisal or an exterior-appraisal only.\nThrough these methods, appraisers rely on information from interested parties, such as borrowers, realtors and other property contacts. The element of measuring and sketches is removed entirely, and extraordinary assumptions are made on condition, quality, deferred maintenance, etc. Appraisers are also using creative techniques such as interviewing homeowners, asking homeowners for photos, or doing video walkthroughs.\nFlexibility in these times remain key, and NAN anticipates more challenges before improvements. It is also important to note that appraisal practices vary by state. For instance, New York prohibited appraisals on March 22\nnd in their stay-at-home order, yet recently reversed the decision stating residential appraisals are essential. Appraisal practices also likely will vary by loan type. For example, an agency lender might be willing to accept an exterior-appraisal if authorized to do so by Fannie or Freddie. Non-agency lenders, on the other hand, may not enjoy the same flexibility to accept something other than a complete internal appraisal, if that is what the rating agencies and bond markets require.\nCurrently, NAN assures us that alternative appraisal turn times align with traditional appraisals, if not faster. For updates on turn times and state laws, we encourage you to visit Nationwide-Appraisal.com/Covid-19.", "pred_label": "__label__POS", "pred_score_pos": 0.9408345222473145}
{"content": "This book investigates international Indigenous methodologies in curatorial practice from the geographic spaces of Canada, Aotearoa (New Zealand) and Australia. From a perspective of Indigenous peoples important place within society, this collection explores how Indigenous art and culture operate within and from a structural framework that is unique and is positioned outside of the non-Indigenous cultural milieu. Through a selection of contributions, Becoming Our Future articulates this perspective, defines Indigenous curatorial practice and celebrates Indigenous sovereignty within the three countries. It begins to explore the connections and historical moments that draw Indigenous curatorial practices together and the differences that set them apart. This knowledge is grounded in continuous international exchanges and draws on the breadth of work within the field.\nWith contributions by Nigel Borell, Nici Cumpston, Freja Carmicheal, Karl Chitham, Franchesca Cubillo, L uli Eshraghi, Reuben Friend, Jarita Greyeyes, Heather Igloliorte, Jaimie Isaac, Carly Lane, Michelle LaVallee, Cathy Mattes, Bruce McLean, Kimberley Moulton, Lisa Myers, Julie Nagam, Wanda Nanibush, Jolene Rickard, Megan Tamati-Quennell, and Daina Warren.", "pred_label": "__label__POS", "pred_score_pos": 0.8516221046447754}
{"content": "Measuring the Performance of Fiscal Reforms: The Case of the GCC\nAhmed Hashim Alyushaa\nPublished: March 2017\nPublic spending has raised the welfare of citizens in the Gulf Cooperation Countries (GCC) significantly over the period 1960–2015, particularly as measured in raised average life expectancy and lowered infant mortality rates. Fiscal policy in oil-producing countries is pro-cyclical, producing sharp fluctuations in the business cycle, but reliance on oil revenue provides challenges for future improvements in development. For the first time in decades all the GCC economies are going through major economic reforms aimed at increasing efficiency while enhancing the economic welfare of the residents. GCC countries are reforming subsidies, particularly for energy, diversifying tax revenues by introducing value-added taxes and privatizing state enterprises in the provision of electricity and water.", "pred_label": "__label__POS", "pred_score_pos": 0.8827580809593201}
{"content": "As Nebraskans begin returning to their homes in the aftermath of widespread historic flooding, Nebraska Extension has mobilized a number of resources to aid in the road to recovery.\nThose affected by the flood are likely unsure of where to begin. Extension encourages individuals returning to homes and properties to first take steps to ensure their safety. When a home or building is flooded, there is likely damage to the structure. Buildings need to be thoroughly dried and it is critical to test domestic wells for bacteria. Also, be cautious when working in and around contaminated floodwater.\nExtension has compiled a list of the state’s certified public health environmental laboratories where homeowners can obtain a water test kit.\nTo read the article about flood resources, visit the KTIC radio website.\nNIFA supports the Nebraska Extension Service.", "pred_label": "__label__POS", "pred_score_pos": 0.9183769822120667}
{"content": "WHO 10 October 2016 – Depression is an illness that can happen to anybody. It causes mental anguish and affects people’s ability to carry out everyday tasks, with sometimes devastating consequences for relationships with family and friends. At worst, depression can lead to suicide. Fortunately, depression can be prevented and treated. Today, on World Mental Health Day, WHO is launching a 1-year campaign: Depression: let’s talk.\nSee: http://www.who.int/campaigns/world-health-day/2017/handouts-depression/en/\nThe handouts available from this page provide general information on the characteristics of depression and how depression can be prevented and treated. They are intended for people who are living with depression themselves or who know someone who is. They include practical advice on what to do.\n- Depression: what you should know\n- Living with someone with depression?\n- Worried that your child is depressed?\n- Worried about the future? Preventing depression during your teens and twenties\n- Wondering why your new baby is not making you happy?\n- Staying positive and preventing depression as you get older\n- Do you know someone who may be considering suicide?\n- Do you feel like life is not worth living?", "pred_label": "__label__POS", "pred_score_pos": 0.8258238434791565}
{"content": "RCT vertasi vähäkalorista ketoa ja standardivähäkalorista ruokavaliota vatsaan asetetulla laihdutuspallolla laihduttavilla. Keto pudotti enemmän rasvamassaa ja vähemmän rasvatonta massaa. Perusaineenvaihdunnan taso aleni ketolla vähemmän.\nImpact of a Low-Calorie Ketogenic vs a Standard Low-Calorie Diet on Fat-Free Mass in Patients Receiving an Elipse™ Intragastric Balloon Treatment Lainaa:\nAbstract\nBACKGROUND The Elipse™ intragastric balloon (EIGB) is a new swallowable balloon for weight loss (WL). Preserving metabolically active fat-free mass (FFM) and resting metabolic rate (RMR) during WL are crucial to maximize fat mass (FM) loss. After EIGB placement, a standard low-calorie diet (LCD) is generally prescribed. A low-calorie ketogenic diet (LCKD) has proven to be safe and effective in reducing FM while preserving FFM and RMR. OBJECTIVE To prospectively compare the effects on WL, FM, FFM, and RMR in two groups of patients who were randomized to two different diets: LCKD and a standard LCD after EIGB placement. METHODS WL, FM, FFM, and RMR were measured before EIGB and at 4 months in 48 patients who received either a LCKD (n = 24) or a standard LCD (n = 24). Compliance in following the prescribed diet was determined with food frequency questionnaires in all patients. The impact of LCKD and LCD on renal function was also evaluated. RESULTS The LCKD group showed a significantly lower decrease in FFM and RMR when compared with the LCD group (3.55 vs 14.3%, p < 0.001, 9.79 vs 11.4%, p < 0.001, respectively). FM decreased more significantly with LCKD compared to LCD (41.6 vs 33.1%, p = 0.0606). Compliance in following the prescribed diets, without negative impact on renal function, was found. CONCLUSION Based on our findings, despite the small sample size, we were able to support the hypothesis that LCKD is associated with an increased FM loss while reducing the FFM loss and the RMR, without interfering with renal function after EIGB.", "pred_label": "__label__POS", "pred_score_pos": 0.7538232207298279}
{"content": "Flow Chemistry at Pfizer\nPaul Richardson, Senior Principal Scientist, Pfizer Worldwide Research and Development\nDespite the significant growth of interest in Flow Chemistry, it is often challenging to integrate this into research programs. This has been reflected in the utility and uptake of this technology within Pfizer. Early adoption focused on the development of reactions in Flow, which would otherwise be difficult to carry out in batch in the research setting for reasons such as safety. Although, this endeavour serves to expand diversity in terms of the chemical space that can be explored within a program, it can be difficult to justify the resource committed to do this based on the short term visible return on investment. As such, there has been a shift to look to judiciously implement Flow solutions to critical problems within the research portfolio, thus displaying the tangible value of the technology. This will be illustrated within this talk with examples being provided of both approaches including the development in Flow of the key step of the synthesis of a current Oncology clinical candidate. This example is unique to our portfolio in that it not only removes several bottlenecks of running the reaction in batch, but also in that the identical reaction fails in batch without additional protecting groups employed.", "pred_label": "__label__POS", "pred_score_pos": 0.6339387893676758}
{"content": "Crystallaria asprella, sole member of the genus Crystallaria, was distributed throughout much of the eastern United States but today persists only in isolated populations. We quantified genetic variation among remaining populations of C. asprella by sequencing the mitochondrially encoded cytochrome b (cyt b) gene in 24 individuals from five sample localities. Phylogenetic analysis of these samples and individuals from eight other darter species, Perca, Gymnocephalus, Stizostedion, and Zingel, resulted in 80 equally most-parsimonious trees. Four of the five populations of C. asprella were monophyletic in all trees. Monophyly of the population from the Cahaba River was supported in 60 of 80 most-parsimonious trees. In the remaining 20 trees, one individual from the Cahaba River was included in a trichotomy with a clade of the other individuals from the Cahaba River and a clade of individuals from the Pearl River. The overall pattern of relationships among populations of C. asprella was (Elk River, WV (Saline River, AR (Zumbro River, MN (Cahaba River, AL, Pearl River, LA)))). The most divergent population of C. asprella is from the Elk River in West Virginia. In spite of considerable collecting effort, only five individuals have been collected from the Elk River since 1987. Crystallaria asprella from the Elk River differ from other populations by 11.2–11.8% sequence divergence. Their continued existence is currently threatened by logging, coal mining, and natural gas exploration. Our data document a distinct evolutionarily significant unit in the Elk River that likely is in great peril and should be protected under the U.S. Endangered Species Act. bSequence Variation in the Crystal Darter Crystallaria asprella(Actinopterygii: Percidae),\" Copeia 2000(1), 20-26, (1 January 2000). https://doi.org/10.1643/0045-8511(2000)2000[0020:CBSVIT]2.0.CO;2", "pred_label": "__label__POS", "pred_score_pos": 0.7091631889343262}
{"content": "Publikationen: Beitrag in Fachzeitschrift › Zeitschriftenaufsätze › Forschung › Begutachtung\nBACKGROUND: The purpose of this study was to analyze sagittal-plane knee biomechanics in individuals with ACL reconstructions in bilateral countermovement jumps. This aimed to determine potential knee compensation strategies during a high-demanding symmetrical movement task from pre to six months post-ACL reconstruction.\nMETHODS: 20 ACL-reconstructed individuals were tested pre-operatively, and then seven weeks, three months, and six months after reconstruction. Additionally, a matched control group was analyzed. Data were sampled with 3D motion capture and two force plates. The following kinematic data were analyzed: peak knee flexion during countermovement, knee angle at toe-off, and knee flexion excursion during landing. The following kinetic data were analyzed: peak knee extension moments during countermovement and landing.\nFINDINGS: ACL-reconstructed individuals showed significant increases in knee flexion during countermovement and knee flexion excursion during landing from six weeks to six months after reconstruction but they remained significantly below the level of the controls. The reconstructed knee joint showed increased flexion at toe-off compared to the non-injured leg at all test sessions. Knee extension moments during countermovement increased up to six months after reconstruction, but remained deficient in ACL-reconstructed individuals during countermovement and landing compared to the controls.\nINTERPRETATION: Although ACL-reconstructed individuals showed increases in most kinematic and kinetic variables, they remained below the controls at six months post-ACL reconstruction. The deficits between contralateral legs and compared to the controls show that six months post-ACL reconstruction, knee joint functionality was still not equal between reconstructed and non-injured legs or in comparison to controls.\nOriginalsprache Englisch Aufsatznummer 105048 Zeitschrift Clinical biomechanics (Bristol, Avon) Jahrgang 77 ISSN 0268-0033 DOIs Publikationsstatus Veröffentlicht - 07.2020\nCopyright © 2020 Elsevier Ltd. All rights reserved.\nID: 5451616", "pred_label": "__label__POS", "pred_score_pos": 0.9991612434387207}
{"content": "Authors:\nT. Stephani, G. Waterstraat, S. Haufe, G. Curio, A. Villringer, V. V. Nikulin\nSummary:\nBrain responses vary considerably from moment to moment, even to identical sensory stimuli. This has been attributed to changes in instantaneous neuronal states determining the system's excitability. Yet the spatio-temporal organization of these dynamics remains poorly understood. Here we test whether variability in stimulus-evoked activity can be interpreted within the framework of criticality, which postulates dynamics of neural systems to be tuned towards the phase transition between stability and instability as is reflected in scale-free fluctuations in spontaneous neural activity. Using a novel non-invasive approach in 33 male human participants, we tracked instantaneous cortical excitability by inferring the magnitude of excitatory post-synaptic currents from the N20 component of the somatosensory evoked potential. Fluctuations of cortical excitability demonstrated long-range temporal dependencies decaying according to a power law across trials – a hallmark of systems at critical states. As these dynamics covaried with changes in pre-stimulus oscillatory activity in the alpha band (8–13 Hz), we establish a mechanistic link between ongoing and evoked activity through cortical excitability and argue that the co-emergence of common temporal power laws may indeed originate from neural networks poised close to a critical state. In contrast, no signatures of criticality were found in subcortical or peripheral nerve activity. Thus, criticality may represent a parsimonious organizing principle of variability in stimulus-related brain processes on a cortical level, possibly reflecting a delicate equilibrium between robustness and flexibility of neural responses to external stimuli.\nSource: The Journal of Neuroscience, 2020; JN-RM-0241-20", "pred_label": "__label__POS", "pred_score_pos": 0.9958581924438477}
{"content": "Abstract\nA field experiment was conducted to collect high spatial and temporal resolution data of various types of high wind events. Winds sampled include those generated from a thunderstorm outflow, hurricane, cold front, and two surface lows. The data were analyzed using the Empirical Mode Decomposition to assess the turbulent and transient nature of the flows. Traditional statistical methods were also used to compare their effectiveness. To complement the analyses, wind tunnel data was evaluated in a similar fashion. The preliminary findings are presented.\nOriginal language English State Published - Jun 2009", "pred_label": "__label__POS", "pred_score_pos": 0.7676222920417786}
{"content": "To mitigate climate risks at the pace needed to create real change, corporate and government leaders must fundamentally shift the way they approach their risk strategies to address climate change challenges.\nWhile finance leaders can, and should, play a crucial role in driving this change in corporate opinion, skepticism has held them back. To push the business community to evaluate climate risks, we must first stop the debate around climate change. Climate science is a legitimate field, and the findings are indisputable.\nAs we enter a new decade, the finance industry needs to correct climate change myths that businesses and governments have been using as excuses for lack of action. To accomplish this, we must start by acknowledging them.", "pred_label": "__label__POS", "pred_score_pos": 0.9999737739562988}
{"content": "David W. Cravens is the Professor of Marketing and the Eunice and James L. West Chair of American Enterprise at Texas Christian University. His research has primarily focused on international/global marketing strategies, new products, and sales force performance.\nMarketing in the 80’s: Changes and Challenges is edited by Richard P. Bagozzi, David W. Cravens, Kenneth L. Bernhardt, Jospeh F. Hair Jr., Paul S. Busch, and Carol A. Scott. This volume is a compilation of proceedings presented at the 1980s Educators’ Conference. The papers focus on the problem and opportunities which would confront marketing in the 1980s. The collection of 124 papers are consolidated in five tracks: research methodology, public policy, marketing management, education, and consumer behavior.", "pred_label": "__label__POS", "pred_score_pos": 0.584013819694519}
{"content": "Detection and Impact of Industrial Subsidies: The Case of World Shipbuilding\nThis paper provides a model-based empirical strategy to, (i) detect the presence and gauge the magnitude of government subsidies and (ii) quantify their impact on production reallocation across countries, industry prices, costs and consumer surplus. I construct and estimate an industry model that allows for dynamic agents in both demand and supply and apply my strategy to world shipbuilding, a classic target of industrial policy. I find strong evidence consistent with China having intervened and reducing shipyard costs by 13-20%, corresponding to 1:5 to 4:5 billion US dollars, between 2006 and 2012. The subsidies led to substantial reallocation of ship production across the world, with Japan, in particular, losing significant market share. They also misaligned costs and production, while leading to minor surplus gains for shippers.\nI am very thankful to Jan De Loecker, Richard Rogerson, Eduardo Morales, as well as John Asker, Panle Jia Barwick, Allan Collard-Wexler and Eugenio Miravete for their helpful discussions of the paper. The paper has also gained a lot from comments by Steve Berry, Chris Conlon, Gene Grossman, Bo Honore, Ariel Pakes, Paul Scott, Junichi Suzuki. Charis Katsiardis and Daniel Goetz provided excellent research assistance. Sarinka Parry-Jones and Natalie Burrows at Clarksons have been extremely helpful. Finally, I gratefully acknowledge the support of the National Science Foundation (under grant SES-1426933), as well as of the Griswold Center for Economic Policy Studies at Princeton University. The views expressed herein are those of the author and do not necessarily reflect the views of the National Bureau of Economic Research.", "pred_label": "__label__POS", "pred_score_pos": 0.6136242747306824}
{"content": "If we think about it, transmit a firm is not only a financial, legal and fiscal question, as too often it is reduced to. It is also and always the transmission of a living property, made with knowledge, culture, values, histories, relationships…\nTransmit is then not only an individual action, born from the supposed unilateral decision’s owner-manager(s) concerned. It is also and always a collective commitment, that concerns and leads the old ones as well as the new leaders, their staff members, their customers, their partners.\nTransmit, it is then not only selling finally and “hand over” to new a owner. It is first and foremost ensuring a continuity, a sense and a sustainability.\nBecause\nentrepreneurship is always a collective action, transmission is always a dynamic one, that projects us into the future. The transmission deserves from everyone a true consideration… and real strategies !", "pred_label": "__label__POS", "pred_score_pos": 0.865310549736023}
{"content": "Real time jobs report data summary. Figures are based on the latest data provided by the Bureau of Labor Statistics (BLS.gov). All jobs numbers are for non-farm employment.\nParamus, NJ Jobs Report\nOctober 2020 Jobs Report Jobs Added Month Over Month: +1.5% 3 Month Average: 123,733 Year Over Year: -10.8% Month Over Month: +1.6% 3 Month Average: 85,400 Year Over Year: -7.6% Month Over Month: +0.5% 3 Month Average: 934,333 Year Over Year: -6.1% Unemployment Rate Month Over Month: -3.5% 3 Month Average: 13% Year Over Year: +6.1% Month Over Month: -4.4% 3 Month Average: 10.67% Year Over Year: +3.1% Month Over Month: -1.0% 3 Month Average: 7.73% Year Over Year: +3.3%\nThe unemployment rate fell rapidly to 6.9 percent, from 7.9 percent in September, adding 638,000 jobs last month, a sign the labor market continues to heal slowly as a resurgence in the coronavirus threatens future growth. This came as a positive this month as the labor force participation rate that rose 0.3 percentage points to 61.7%.\n“The strength of this report is really amazing in the face of rising coronavirus cases,” said Michael Arone, chief investment strategist at State Street Global Advisors. The U.S. economy has recovered two-thirds of the ground it lost during the first half of the year.\nSector Job Growth from the B.L.S. Month Over Month: +0.2% 3 Month Average: 1,449 Year Over Year: -10.1% Month Over Month: +2.2% 3 Month Average: 1,864 Year Over Year: -7.4% Month Over Month: +1.4% 3 Month Average: 1,539 Year Over Year: -9.6% Industry Job Growth from the B.L.S. Month Over Month: 0.0% 3 Month Average: 60 Year Over Year: -7.0% Month Over Month: +4.9% 3 Month Average: 37 Year Over Year: -12.4% Month Over Month: +2.2% 3 Month Average: 130 Year Over Year: -4.5% Month Over Month: +4.2% 3 Month Average: 19 Year Over Year: -16.7% Metropolitan Month-Over Month Job Growth by Sector\n*The following chart displays the latest local job growth by sector compared to the previous month. Note that if a sector experienced losses or flat growth, it will not be displayed as part of the graphic.\nBLS.gov cannot vouch for the data or analyses derived from these data after the data have been retrieved from BLS.gov.\nThe BLS defines a sector as a subset of the domestic economy and excludes the economic activities of the following: general government, private households, and nonprofit organizations serving individuals. A sector consists of multiple industries.\nThe BLS defines an industry as a group of establishments that produce similar products or provide similar services. Multiple industries makeup sectors.", "pred_label": "__label__POS", "pred_score_pos": 0.9855937957763672}
{"content": "The US Treasury, Department of Health and Human Services (HHS) and Centers for Medicare and Medicaid Services (CMS) have implemented financial relief and regulatory flexibility to support health care entities through the unparalleled impact of the COVID-19 pandemic.\nOn May 20, 2020, Kelly Saunders, Chris Anusbigian, and Linsday Wisdom of Deloitte presented a webinar through the MA-RI chapter of HFMA on these important changes and have further summarized them here. For further details, follow this link to the recorded webinar and presentation from May 20, 2020.\nProvider Funding\nA total of $175 billion has been allocated for the Provider Relief Fund, including $100B through the Coronavirus Aid, Relief, and Economic Security (CARES) Act and $75B through the Paycheck Protection Program and Health Care Enhancement Act. To date, roughly $70.4B has been allocated across Medicare fee-for-service providers, high-impact areas, rural providers and Indian Health Service. A significant portion of the Provider Relief Fund, roughly $104.6B, has yet to be distributed. However, HHS has stated that a portion of the remaining amount will be used to reimburse for uninsured patients and certain other provider types, including skilled nursing facilities, dentists and providers who solely accept Medicaid.\nRecent Updates\nHHS offers guidance in the\nCARES Act Relief Fund FAQs, (link to https://www.hhs.gov/sites/default/files/provider-relief-fund-general-distribution-faqs.pdf) on a variety of topics aimed at assisting organizations as they prepare to accept, return, and/or apply for additional funding through the General Distribution attestation portal. Importantly, HHS has stated that funds determined to be overpaid or paid in error should be rejected in their entirety, and providers should submit the appropriate revenue documents through the General Distribution portal to facilitate HHS determining correct payment. Additionally, if providers believe they have been underpaid, they should accept the payment and submit their revenues in the provider portal to determine correct payment.\nFurther FAQs on balance billing, situations where organizations/facilities have been recently purchased or sold, new TIN owners, and whether a provider that owns several hospitals has discretion to allocate throughout the system can be found using the link provided above.\nKey Dates and Deadlines\nFor entities in receipt of funds from the General Distribution, the Provider Relief Fund attestation must be completed via the CARES Act Provider Relief Fund Payment Attestation Portal within 45 days of receipt of funds; this includes agreement to the accepted amount and the Terms and Conditions.\nIf the amount an entity has received to date does not cover lost revenue or increased expenses, requests for additional funds from the General Distribution can be made via the Attestation Portal by submitting the required supporting financial documentation. The deadline to request additional funds is June 3, 2020.\nWe recommend monitoring the HHS website and the\nHFMA COVID-19 News page (link to https://www.hfma.org/topics/coronavirus.html) for updates. Waivers & Telehealth CMS has issued blanket waivers (link to https://www.cms.gov/files/document/summary-covid-19-emergency-declaration-waivers.pdf) for certain hospital conditions of participation, flexibility across types of facilities types and expansion of telehealth services. These blanket waivers are retroactively effective from March 1, 2020 through the declared end of the public health emergency.\nCMS has promoted the use of telehealth services through removing geographic restrictions, expanding the types of allowed providers, increasing telehealth reimbursements to in-person fee-for-service rates and, through Office of Civil Rights (OCR) direction, allowed use of readily-available applications such as Apple FaceTime, Zoom and Skype. Please reference the recording and presentation through the link above for details on specific telehealth coding and billing information.\nWhile support is available to help navigate the clinical, operational and financial hardship caused by COVID-19, knowing how to appropriately use the resources and relief is vital to success. Please stay on the lookout for future HFMA webinar sessions around COVID-19 current events.\nAbout the Authors: Kelly J. Sauders is a Partner at Deloitte & Touche LLP with over 25 years of experience in the health care industry. She specializes in providing regulatory compliance, risk and control-related services. Chris Anusbigian is a Specialist Leader at Deloitte & Touche LLP. Chris has over 30 years of experience working with health care and life sciences organizations around regulatory requirements, third-party payor billing rules and compliance programs. Lindsay Wisdom is a Manager at Deloitte & Touche LLP where she assists organizations in developing solutions and strategies to address a variety of complex organizational and regulatory risks and challenges. Dhara Satija , Senior Manager and Tully Saunders, Manager, from Deloitte & Touche LLP also contributed to this blog and webinar.", "pred_label": "__label__POS", "pred_score_pos": 0.898249626159668}
{"content": "This study set out to uncover how participants represent their experiences in a professional development institute for multimodal composition. Though clearly locally situated, the study’s findings are relevant for WPAs in a variety of contexts looking to design similar programs. They also suggest some pressing issues for the field of writing studies as it aims to prepare students for 21st-century environments. The following sections extend this study’s findings to larger disciplinary conversations and explore key issues this study raises for future research and practice.", "pred_label": "__label__POS", "pred_score_pos": 0.9997685551643372}
{"content": "While data is at the heart of business and technology, many organizations are unable to leverage these silos of wealth and make them useful, due to challenges in consolidating and sharing the information. Unlocking the power of data is key to creating a competitive advantage. This infographic looks at the volume, velocity, variety, veracity, and value of the data in organizations today.\nInfographic Courtesy of Omnivex Photo Credit: iStockPhoto.com\nPhoto Credit: iStockPhoto.com\nHow digital communications can transform HR - October 25, 2018 How digital maturity is affecting core operations and value - October 18, 2018 Standalone digital communications displays are dead - May 3, 2018 Does your business need the Internet of Things and Blockchain? - April 19, 2018 Does your business need virtual reality and artificial intelligence? - March 14, 2018 AI is changing the face of retail - February 21, 2018 Big data in digital communications - January 17, 2018 Why unused data is a virtual goldmine - December 8, 2017 AI opens unforeseen opportunities for digital communications - December 6, 2017 Generating a tangible ROI with digital signage - November 8, 2017", "pred_label": "__label__POS", "pred_score_pos": 0.9555951952934265}
{"content": "B-type natriuretic peptide (BNP) is a cardiac hormone secreted predominantly from the ventricles in response to increased ventricular pressure. Along this line, hypertensive patients with left ventricular hypertrophy typically have high circulating BNP concentrations. BNP has natriuretic and vasodilatory actions. Obese persons have low circulating BNP concentrations, and a relative lack of this natriuretic and vasodilatory factor could contribute to obesity-related hypertension. The relationship between BNP, BP, left ventricular mass (LVM), and left ventricular filling pressure among obese persons is not clear. To address this issue, we studied 98 healthy obese medication-free men with normal left ventricular ejection fraction. We measured BP using 24 -h ambulatory (A) BP recordings, LVM and E/e', an estimate of left ventricular filling pressure, using echocardiography, and fasting BNP in serum. Mean systolic ABP ± SD was 114 ± 4 mm Hg in 1st and 149 ± 8 mm Hg in 4th systolic ABP quartile, P < 0.001. LVM and E/e' increased across systolic ABP quartiles (mean LVM±SD: 81.5±13.7 g/m2 in 1st and 100.1 ± 26.7 g/m2 in 4th quartile, P = 0.018; mean E/e'±SD: 5.3±1.6 in 1st and 7.0 ± 2.0 in 4th quartile, P = 0.002). In contrast, serum BNP did not increase across systolic ABP quartiles (median (IQR): 6.7 (3.1-12.3) pg/ml in 1st and 5.3 (2.8-9.7) pg/ml in 4th quartile, P = 0.75). Unexpectedly, among healthy obese medication-free men, serum BNP does not increase with higher systolic ABP despite evidence of BP-related increases in LVM and E/e'. This further suggests that a relatively low amount of circulating BNP could contribute to obesity-related hypertension in its early stages.", "pred_label": "__label__POS", "pred_score_pos": 0.761121392250061}
{"content": "Abstract\nWe tested three innovation network governance mechanisms for exploring and exploiting innovation opportunities. We analysed household-level panel data from agricultural innovation networks in Uganda, the Democratic Republic of the Congo and Rwanda. We found that first-order governed networks fostered capabilities for exploitation as well as exploration, while second-order governed networks fostered specialised capabilities for exploitation. Meta-governed innovation networks were most effective in combining multiple capabilities for exploration and exploitation. However, our results indicate that the relationship between network governance and ambidexterity of innovation networks is not robust, and we recommend further research on the context as a mediating factor between network governance and capabilities.\nKeywords Africa Ambidexterity Capabilities Challenges Innovation Innovation platforms Network governance", "pred_label": "__label__POS", "pred_score_pos": 0.7213236093521118}
{"content": "A new competition has been launched to encourage more young people to consider careers in science, technology, engineering and maths (STEM) industries.\nThe Formula 100 competition, set up by Your Life, a three-year campaign aimed to encourage STEM careers in the UK, will invite pupils aged 11-18 to submit a 30-second video answering “what would you invent and why?”\nThe best entrants will then win prizes such as trips to Rio Tinto’s diamond plant in Belgium, a day at a Ford test track or a day with the BT Sports team.\nThe competition will work to build a group of 100 students, who will be offered the support of entrepreneurs and business figures to guide their career choices.\nThe competition has three age categories (11-13, 14-15 and 16-18) and runs until February 15 this year.\nThe winners will be announced on the Your Life Twitter and Facebook page @YourLifeTeam throughout the competition.\nStudents can submit their entry by emailing Formula100@yourlife.org.uk with their video, name, age, school and contact details.\nThey can promote their entries on Twitter, Vine and Instagram using the hashtag #Formula100.", "pred_label": "__label__POS", "pred_score_pos": 0.8520327806472778}
{"content": "A new IHA guide will help hydropower developers and operators manage potential impacts arising from\nerosion and sedimentation in a river basin, allowing decision-makers to avoid business risks and act responsibly towards the environment and local communities.\nThe Hydropower Erosion and Sedimentation How-to Guide provides an overview of current knowledge and effective practices from across the sector in managing risks associated with erosion and sedimentation.\nIt covers potential impacts upstream and downstream of a hydropower project, sediment transport in rivers, erosion from the project site, civil and electromechanical structures, and climate change.\nThe guide presents methodologies and technologies related to scoping and siting, design and mitigation, and assessment and monitoring. The guide in addition highlights how such measures can increase a project’s resilience to hydrological variability and support climate change adaptation.\nIHA Sustainability Specialist, Alain Kilajian, said: “Effective erosion and sediment management is essential to sustainably develop and operate a hydropower project. This guide looks at good practices in the field and provides hydropower professionals with practical approaches to managing even the most challenging issues.”\nLead author and independent environmental and social consultant, Doug Smith, said: “Effective management of erosion and sedimentation is fundamental to hydropower’s role in a low carbon future. With its catalogue of methodologies and technologies, I hope the guide provides clarity on how to do this, where to begin, and where to find further advice and expertise.”\nDownload the Hydropower Erosion and Sedimentation How-to Guide.", "pred_label": "__label__POS", "pred_score_pos": 0.7618390917778015}
{"content": "Don’t Lose Your License\nIn Ohio, even first-time offenders of driving while impaired (known as OVI or DUI) face harsh penalties. Your license will be suspended. You will face up to $1,000 in court fees and six months in jail. For repeat offenders, the punishments are more severe still.\nYet the authorities are often overzealous in their pursuit of OVI/DUI matters. In many cases, they make procedural errors that an experienced attorney will know how to challenge. Indeed, finding the right lawyer can be the difference between enduring punishment and getting relief.\nWhat We Do\nThe lawyers at Arenstein & Gallagher have earned a reputation for successfully defending clients against OVI/DUI charges. Drawing on more than 60 years of combined experience, we thoroughly understand the law – and know how to challenge law enforcement officers effectively.\nWe will investigate every aspect of the allegations against you, from the initial stop through the field sobriety tests and the relevant court filings. If a mistake has been made at any juncture, we will find it and leverage it to your advantage. We understand the stakes involved and work hard to protect our clients’ rights.\nWhat If I’m A Minor?\nThe laws regarding impaired driving are somewhat different for minors than they are for adults. As with many juvenile crimes, the penalties tend to be slightly more lenient – the maximum fines and prison terms are somewhat shorter, and minors receive fewer points against their driver’s license.\nHowever, the law is less tolerant of minor drinking. Individuals under the age of 18 face arrest if their blood alcohol level is higher than .02, whereas for adults the threshold is .08.\nHelping You Keep Your Driving Privileges\nWe offer free initial consultations, so that we can assess your case before you are obliged to retain us.", "pred_label": "__label__POS", "pred_score_pos": 0.589923083782196}
{"content": "Victims of serious motor vehicle accidents caused by negligence should never have difficulty acquiring compensation. Unfortunately, financial compensation must often be fought for and won even when you are a victim.\nNew Jersey’s compensation laws are complex, which means that you might benefit from legal assistance. For example, our state follows the modified comparative negligence standard. If you played a role in causing the crash, then your compensation is adjusted accordingly. If you are more than 50% at fault for the crash, you may walk away with no compensation at all.\nThe auto insurance policy you have can also influence how you acquire compensation. A basic insurance policy in our state limits your ability to sue the other motorist for pain and suffering damages. If the crash resulted in permanent injuries, you may sue. If you suffered no permanent injury, then you may not file a lawsuit.\nBy comparison, a standard policy gives you the option to choose certain elements of your coverage. For example, when purchasing your policy, you must choose between the limited right to sue as described above and the unlimited right to sue. The latter choice preserves your right to seek a legal remedy against the person who caused the motor vehicle accident.\nAs you can see, these laws are difficult to sort through, especially for safe drivers who believe they can avoid motor vehicle accidents. If the worst happens and you suffer injuries in a crash, you can make your circumstances simpler. Consider having a legal advocate help you target all sources of compensation. This leaves you free to continue recovering while your lawyer works through the legal details and the red tape.\nWe invite you to continue reviewing our blog and website to learn more about your options after a motor vehicle crash in New Jersey.", "pred_label": "__label__POS", "pred_score_pos": 0.5244781970977783}
{"content": "Acoustic models in real-time speech recognition systems typically stack multiple unidirectional LSTM layers to process the acoustic frames over time. Performance improvements over vanilla LSTM architectures have been reported by prepending a stack of frequency-LSTM (FLSTM) layers to the time LSTM... These FLSTM layers can learn a more robust input feature to the time LSTM layers by modeling time-frequency correlations in the acoustic input signals. A drawback of FLSTM based architectures however is that they operate at a predefined, and tuned, window size and stride, referred to as 'view' in this paper. We present a simple and efficient modification by combining the outputs of multiple FLSTM stacks with different views, into a dimensionality reduced feature representation. The proposed multi-view FLSTM architecture allows to model a wider range of time-frequency correlations compared to an FLSTM model with single view. When trained on 50K hours of English far-field speech data with CTC loss followed by sMBR sequence training, we show that the multi-view FLSTM acoustic model provides relative Word Error Rate (WER) improvements of 3-7% for different speaker and acoustic environment scenarios over an optimized single FLSTM model, while retaining a similar computational footprint. (read more)PDF", "pred_label": "__label__POS", "pred_score_pos": 0.7566537857055664}
{"content": "'Beyond Procedural Justice'\nThe Significance of Personal and Community Relationships in Countering Terrorist Recruitment\nPublished in: NATO Science for Peace and Security Series - E: Human and Societal Dynamics. Vol. 125: Countering Terrorist Recruitment in the Context of Armed Counter-Terrorism Operations, Mar. 2 / Ekici, S., Akdoğan, H., Ragab, E., Ekici, A., Warnes, R. (Amsterdam: IOS Press, 2016), p. 221-238\nPosted on RAND.org on March 09, 2016\nThe Procedural Justice Model has traditionally been associated with the fields of sociology and criminology as a means for those representing the criminal justice system, in particular the police, to interact and engage with local communities, build trust, develop legitimacy and establish institutional authority. However, in the context of domestic counter-terrorism, such concepts can provide the bedrock and basis for the awareness and input of 'unlikely counter-terrorists' from within the local community, the recruitment of sources for 'Human Intelligence' (HUMINT) and the development of a more permissive operational environment. Additionally, since such 'human centric' measures begin with the development of personal relationships with members of the local community, they are eminently transferable to overseas environments where armed counter-terrorism operations are being conducted. It is argued that such measures can prove critical in countering terrorist recruitment.", "pred_label": "__label__POS", "pred_score_pos": 0.6393274068832397}
{"content": "As impact investing gains momentum worldwide, traditional and thematic investors are increasingly interested in African opportunities and the approaches of various African policy-makers and regulators to ‘purpose-driven’ enterprises and financial products.\nLexology’s\nImpact Economy Digital Edition, 2021 is a valuable aid to understanding this shifting legal and regulatory landscape. Bowmans, with a presence in seven countries in Africa and a global reputation for thought...", "pred_label": "__label__POS", "pred_score_pos": 0.9293074607849121}
{"content": "What is a Confirmed Case?\nMontrose County COVID-19 Patients who have received a positive molecular test result (ie nasal swab test or saliva test). This includes all cases that report Montrose County as their primary residence. This number may fluctuate as cases are investigated and then added/removed. Reasons for adding/removing are often due to incorrect county assignment, duplicate tests submitted to the state lab, or clarification of name/address during interviews.\nWho is Counted in Deaths?\nThese are deaths of those that have been confirmed to have “died\nfrom” COVID-19 and “died with“; as reported by CDPHE. What is Positivity Rate?\nThis is the percent of confirmed positive tests divided by the total number of tests (within the defined period that is confirmed as positive).\nOn the County COVID-19 Dashboard, What Tests are Included?\nThis number includes only COVID-19 tests for Montrose County residents. This number doesn’t include antigenic, or serologic testing. This number does include indeterminate tests as well as incomplete tests due to shipping or processing issues.\nOn the County COVID-19 Dashboard, What Does Hospitalizations Mean?\nThis number represents current hospitalizations at Montrose Memorial Hospital.\nWhat is the 2-Week Case Rate?\nExpressed as the number of cases per 100,000 residents reported in the last 14-day interval. This is based on Montrose’s current estimated population of 42,758.\nWhy are Montrose County’s COVID-19 positive case and death totals different from the state’s totals?\nPlease note that the State (CDPHE) has added cases to the county’s total number of cases because the state feels they meet the definition of a probable case (see FAQ). These additional cases are being reflected on the state’s data; however, the county has testing resources and was able to test those individuals. The individuals in question (and the additional death) were all tested and received negative COVID-19 results. As such, the county will not count them in its reported total of cases.\nWhy is the county’s COVID-19 death total different than the state’s total?\nIn a review of outbreak sites that were identified in April, the state attributed another probable death to the county. This individual was in prolonged contact (at least 15 minutes) with a positive case as well as exhibited some symptoms; however, when tested, this individual was negative and as such will not be included in the county’s death total. The county will keep track of these cases that the State defines as a death but with a negative test result separately.\nWhat’s the difference between confirmed and probable cases (per CDPHE)?\nThe total number of cases reported by the State includes both confirmed and probable cases.\nCases are considered confirmed when there has been a positive molecular amplification test (such as PCR) performed by a lab. These tests commonly involve taking a nasal swab which is then sent to specific laboratories for results. A molecular amplification test detects genetic material from the virus indicating presence of the virus. Cases are considered probable when they meet one of the following criteria: A person exhibited symptoms AND had close contact with someone who tested positive OR A person exhibited symptoms AND tested positive using an antigen or serologic test. An antigen or serologic test is a blood test that looks for antibodies in your blood. This test can detect the body’s immune response to the infection caused by the virus rather than detecting the virus itself. OR A person has an epidemiologic link AND has tested positive using an antigen or serologic test * *An epidemiologically-link is close contact with a confirmed or probable case of COVID-19 disease OR travel to or residence in an area with sustained, ongoing community transmission OR a member of a risk cohort as defined by public health authorities during an outbreak. OR A death certificate lists COVID-19 disease or SARS-CoV-2 as a cause of death or a significant condition contributing to death with no confirmatory laboratory testing performed for COVID-19. A person exhibited symptoms AND had close contact with someone who tested positive What is the definition of a COVID-19 death (per CDPHE)?\nWhen reporting deaths, we follow a standardized case definition of COVID-19 as set by the Council of State and Territorial Epidemiologists. This includes both confirmed and probable case deaths:\nA death is classified as a confirmed case if the decedent had a positive COVID-19 lab test. A death is classified as a probable case if the decedent meets probable case definition or the death certificate lists “COVID-19” or an equivalent as a cause of death but does not have a positive lab test. Why is Montrose County not counting probable cases in totals or including the recently added cases?\nThe county is working with the Coroner to determine those cases who died from COVID versus those who died with COVID or a history of COVID.", "pred_label": "__label__POS", "pred_score_pos": 0.8714674711227417}
{"content": "The virus was almost always detected in the spinal cord (93%) and the neopallium (87%); often in the midbrain (83%) and pons (67%); and about half the time in the diencephalon, cerebellum, and paleopallium. The practical implications of these findings for routine diagnosis are highlighted separately (online Technical Appendix 5, http://wwwnc.cdc.gov/EID/article/20/8/12-1890-Techapp5.pdf).", "pred_label": "__label__POS", "pred_score_pos": 0.9892460703849792}
{"content": "Non-volatile memories (NVMs) such as Spin-Transfer Torque RAM (STTRAM) have drawn significant attention due to complete elimination of bitcell leakage. In addition to the plethora of benefits such as density, non-volatility, low-power and high speed, majority of Non-Volatile Memories (NVMs) are also compatible with CMOS technology enabling easy integration. Although promising, NVM brings new security challenges that were absent in their conventional volatile memory counterparts such as Static RAM (SRAM) and embedded Dynamic RAM (eDRAM). The root cause is persistent data that may allow the adversary to retrieve sensitive information like password or cryptographic keys. This is primarily due to the fundamental dependency of these memory technologies on environmental parameters such as magnetic fields and temperature which can be exploited by the adversary to tamper with the stored data. This paper investigates the data security and privacy challenges in NVMs by exploring the security specific properties and novel security primitives realized using spintronic building blocks. A thorough analysis is done on the vulnerabilities, data security and privacy issues, threats and possible countermeasures to enable safe computing environment using spintronics.", "pred_label": "__label__POS", "pred_score_pos": 0.8249883651733398}
{"content": "Sabinsa Corporation today announced that it has secured a U.S. patent for its branded ingredient Cococin™, a freeze-dried powder form of green coconut water. In addition to Sabinsa's derivation process, U.S. patent #7,300,682 secures exclusive rights to the resulting vitamin-rich composition and its intended uses in cosmetics, supplements and foods and beverages to support healthy cell growth and improve overall dermal health, among others.\n\"Coconut water's staggering level of active ingredients provides an exceptionally rich repository of vitamins, minerals and amino, shikimic and quinic acids essential for healthy tissue growth, resulting in an optimal ingredient for today's cosmeceutical market,\" said Dr. Lakshmi Prakash, vice president of innovation and business development, Sabinsa Corporation. \"We have worked diligently to secure this processs, composition and use patent to ensure a safe and efficacious ingredient resulting from Sabinsa's high-quality, nutrient-preserving freeze-dried process.\"\nSabinsa's process extracts green coconut water, a liquid endosperm of maturing coconut, at optimal maturity when high levels of RNA, critical for amino acid transport and respiratory metabolism of living cells, are present. Long considered a refreshing beverage and even a natural sports drink in Southeast Asia, Central America and other tropical regions, green coconut water has been valued for its regenerative benefits.\nIn addition to Cococin's U.S. protection, the branded ingredient was also granted European Patent #EP1341547 for process, composition and use in the European Market.", "pred_label": "__label__POS", "pred_score_pos": 0.6574599742889404}
{"content": "Licorice Plus is a specially designed, herbal adrenal support formula for individuals who are \"burned out and exhausted.\" It features standardized extracts of licorice and ashwagandha combined with rehmannia and Chinese yam.\nSupports proper adrenal function, which is associated with a healthy physiological response to stress.\nFeatures licorice, an herb with an unparalleled reputation for promoting longevity, vitality, respiratory function, and healthy immunity.\nProvides ashwagandha, an Ayurvedic herb with renowned adaptogenic properties, that is often referred to as \"Indian ginseng.\"\nProvides highly valued Chinese herbs traditionally used to tonify kidney \"yin\" and promote overall health.\nLicorice Plus 60 tablets by Metagenics\nSupplement Facts\nServing Size: 2 Tablets Servings per Container: 30\nAmount per Serving\nLicorice Root Extract (Glycyrrhiza glabra)\n600 mg\n[standardized to 25% (150 mg) glycyrrhizic acid]\nAshwagandha Root 5:1 Extract (Withania somnifera) (containing withanolides)\n100 mg\n[containing withanolides]\nA 4:1 proprietary herbal extract blend of:\n500 mg\nRehmannia Root (Rehmannia glutinosa)\nChinese Yam Root (Dioscorea oppositifolia)\nOther Ingredients: Microcrystalline cellulose, cellulose, croscarmellose sodium, stearic acid, silica, and coating (deionized water, microcrystalline cellulose, polyethylene glycol, and carrageenan).\nWarning: Do not exceed 600 mg of glycyrrhizic acid daily. Extended use at these levels may elevate blood pressure.\nCaution: If pregnant or nursing, hypertensive, or taking medication, consult your healthcare practitioner before use.\nRecommendations: Two tablets one to two times daily or as directed by your healthcare practitioner.\nThis product is not available in any additional sizes, forms, or flavors.", "pred_label": "__label__POS", "pred_score_pos": 0.8600479960441589}
{"content": "TIMBER\nGlobal Traceability was founded to address traceability requirements for the timber industry, such as the EU Timber Regulation and the Lacey Act.\nThanks to RADIX Tree and our dedicated team of timber experts, Global Traceability is the global market leader in timber traceability solutions.\nSeafood\nThe sustainability of our fish stocks is critical to the global food supply, making it more important than ever to ensure the integrity of seafood supply chains. We have developed solutions to implement full chain of custody traceability, assuring a product’s claims can be verified along the whole supply chain. This is vital for consumer trust in sustainable seafood products.\nBIOMASS\nGlobal Traceability partners with biomass certification scheme SBP to assure biomass is sourced from legal and sustainable sources.\nGlobal Traceability provide the tool to facilitate the collection, collation and transmission of a range of data, including emissions data, along the biomass supply chain, ensuring a clear and effective data transfer solution for SBP certificate holders, which is both manageable and auditable\nPUBLISHING\nGlobal Traceability have developed a dedicated solution for the publishing industry that enables the sharing of supply chain sustainability information to ensure paper products are sourced from sustainable timber.", "pred_label": "__label__POS", "pred_score_pos": 0.9411830902099609}
{"content": "Research\nOur body is colonized by a robust and diverse ecosystem termed the commensal microbiome. When mucosal pathogens infect us, they first encounter our commensals before they encounter and activate our immune response.\nWe are interested in studying the interactions between the commensal microbiota, pathogens and the host immune response in the one place they must necessarily meet – the mucosa. Studying host-pathogen interactions at the mucosa allows us to exploit the Red Queen Hypothesis (co-evolving organisms locked in competition) as a discovery tool to identify novel pathways and mechanisms by which we resist or tolerate infections. We have multiple projects aimed at studying the mechanisms by which pathogens activate and evade the mucosal immune response and how these interactions are modulated by the microbiota. Our goal is to generate and test new ideas for vaccine and drug candidates to better protect people against infectious disease.\nWe're located at the Department of Immunology and Infectious Diseases at the Harvard T.H. Chan School of Public Health. Come join us!\nVaginal Microbiome\nUnlike the intestinal microbiome, the vaginal microbiome consists of a smaller and more defined set of bacterial communities. The vaginal microbiome is also more consistent in people across the world, across diverse diets and ethnicities. Changes in the vaginal microbiome have been linked to increased susceptibility to and transmission of sexually transmitted infections. We are interested in bacterial community interactions of vaginal commensals and how this impacts host immunity to sexually transmitted diseases.\nGut-Vaginal Signaling Axis\nThe gut microbiome can influence distal sites in the body including the skin. We want to understand how the gut microbiome influences vaginal immune homeostasis. It was recently discovered that genital herpes infections can result in viral infection of the enteric neurons in the colon. We will use this model to study how the vaginal immune response can prime and control enteric viral infections.\nAminoglycoside Antiviral Signaling\nWe recently discovered that aminoglycosides (commonly used antibiotics) can induce antiviral gene transcription in dendritic cells, resulting in broad antiviral protection. We want to understand the intracellular signaling pathways involved, so we can build better antivirals.", "pred_label": "__label__POS", "pred_score_pos": 0.5378141403198242}
{"content": "To see the issue content and the abstract you do not have to login\nPlease login to download the full articles\nIf you do not have a subscription to Rhinology please consider to take one.\nVolume: 58 - Issue: 5 First page: 489 - Last page: 494 B. Chen - A. Haehner - M.K. Mahmut - T. Hummel\nBACKGROUND: Patients with olfactory deficits often report rapid and lasting olfactory adaptation compared to the time when they had normal olfactory function. However, this phenomenon receives little scientific attention. This retrospective study aimed to compare the patterns of olfactory adaptation in normosmic controls and patients with olfactory impairment by analyzing the trajectory of turning points in odor threshold tests based on the staircase technique.\nMETHODS: 4120 subjects (1684 hyposmia, 1742 anosmia and 694 normosmic controls) were included in this study. Their odor threshold, odor discrimination and odor identification ability were assessed using the Sniffin’ Sticks. We analyzed the trajectory of turning points in the odor threshold test. RESULTS: Current results suggested that patients with hyposmia needed significantly more trials to reach the final threshold scores than controls and anosmic group, and controls needed more trials than anosmic group. The difference between the first turning point and final threshold scores in the anosmic group was significantly larger than in the hyposmia group and in controls. CONCLUSION: People with poor olfaction seem to adapt faster to olfactory stimuli. The trajectory of turning points in odor threshold test may serve as an indicator of olfactory adaptation and function of olfactory receptors. Olfactory adaptation may provide a new tool in the assessment of subtle olfactory loss. B. Chen - A. Haehner - M.K. Mahmut - T. Hummel - Faster olfactory adaptation in patients with olfactory deficits: an analysis of results from odor threshold testing Rhinology 58-5: 489-494, 2020", "pred_label": "__label__POS", "pred_score_pos": 0.9424707889556885}
{"content": "Article # 2560 Journal Rhinology 58 - 4 Article Title Analysis of expression profiling data suggests explanation for difficulties in finding biomarkers for nasal polyps Abstract BACKGROUND: Identification of clinically useful biomarkers for Nasal Polyposis in chronic rhinosinusitis (CRSwNP) has proven dif-ficult. We analyzed gene expression profiling data to find explanations for this.\nMETHODS: We analyzed mRNA expression profiling data, GSE36830, of six uncinate tissues from healthy controls and six NP from CRSwNP patients. We performed Ingenuity Pathway Analysis (IPA) of differentially expressed genes to identify pathways and predicted upstream regulators.\nRESULTS: We identified 1,608 differentially expressed genes and 177 significant pathways, of which Th1 and Th2 activation pathway and leukocyte extravasation signaling were most significant. We identified 75 upstream regulators whose activity was predicted to be upregulated. These included regulators of known pathogenic and therapeutic relevance, like IL-4. However, only seven of the 75 regulators were actually differentially expressed in NP, namely CSF1, TYROBP, CCL2, CCL11, SELP, ADORA3, ICAM1. Interes-tingly, these did not include IL-4, and four of the seven were receptors. This suggested a potential explanation for the discrepancy between the predicted and observed expression levels of the regulators, namely that the receptors, and not their ligands, were upregulated. Indeed, we found that 10 receptors of key predicted upstream regulators were upregulated, including IL4R.\nCONCLUSION: Our findings indicate that the difficulties in finding specific biomarkers for CRSwNP depend on the complex underly-ing mechanisms, which include multiple pathways and regulators, each of which may be subdivided into multiple components such as ligands, soluble and membrane-bound receptors. This suggests that combinations of biomarkers may be needed for CRSwNP diagnostics.\nPrice 25 €", "pred_label": "__label__POS", "pred_score_pos": 0.9807547330856323}
{"content": "We might suspect that great manifestations of the miraculous power of God would lead to great faith and confidence in Him. It sometimes may, but only in a temporary and limited sense.\n\"A great multitude followed Him because they saw His miracles which He did on them that were diseased\" (John 6:2).\n\"But though He had done so many miracles before them, yet they believed not on Him\" (John 12:37).\nTrue and lasting faith results primarily from hearing and receiving God's Truth as revealed in the Scriptures. \"Faith cometh by hearing, and hearing by the Word of God\" (Romans 10:17). Certainly, God's working may help prepare our hearts to believe, or confirm existing confidence in His loving presence and involvement. Nevertheless, merely witnessing the actions of the Lord's hand can never lead us to trust His heart. Truth, the Truth of Scripture, rather ushers us into the faithful relationship whereby we know His love, and love Him in holy response. Indeed, no one has ever been born again by witnessing a miracle, and then believing that God performed the act of transcendent power and greatness. Salvation rather results from believing Truth, that is, from believing the Gospel of a Christ we cannot see, who died a death for our sins that we did not witness, and then rose again in a resurrection accomplished long before we were born. \"I am not ashamed of the Gospel of Christ, for it is the power of God unto salvation to every one that believeth… I declare unto you the Gospel which I preached unto you…that Christ died for our sins according to the Scriptures, and that He was buried, and that He rose again the third day according to the Scriptures\" (Romans 1:16; I Corinthians 15:1; 3-4).\nWhen God chooses to perform an open and mighty act of His power, we rejoice and seek to benefit from the display of His glorious ability. We do not, however, base our faith on such unpredictable manifestations. We rather look to the perfectly predictable means of daily exposing ourselves to the Word of God, whereby \"faith cometh.\" While perhaps not outwardly spectacular, thrilling, or exciting, the growing relationship with our Lord that results from such devotion solidifies and enhances existing faith, while also initiating new aspects of confidence in God. Most importantly, such communication between Heart and heart constitutes our bond with the Lord in terms of personal relationship and fellowship rather than our being merely spectators at Divine events.\nNo human eye witnessed the actual resurrection of the Lord Jesus. However, no human heart can be saved apart from believing the witness of the Word of God that \"now is Christ risen from the dead\" (I Corinthians 15:20). Thus, the greatest of all miracles calls us to believe Truth about the great event apart from witnessing the wonder it must have been. This is the way of God in those with whom He desires living communion that may sometimes benefit from displays of power, but which most often thrives in discourse between persons, namely, the proclamation of Truth as declared by the Word and Spirit of God unto trusting believers seeking His heart.\n\"We walk by faith, not by sight.\"\n(II Corinthians 5:7)\n\"Sanctify them through Thy truth; Thy Word is truth.\"\n(John 17:17)\nWeekly Memory Verse\nWho can understand his errors? Cleanse thou me from secret faults.\n(Psalm 19:12)", "pred_label": "__label__POS", "pred_score_pos": 0.9469647407531738}
{"content": "Milium (plural, Milia) is the medical name for the whitehead, which is a small, round, white skin growth. Milia are usually found on the face and are common and harmless. Milia may appear after a superficial skin injury such as a burn or scrape. However, we usually don’t know why people grow milia. They tend to appear in adults, especially in those who had considerable sun exposure over the years. Sometimes they appear in crops in young people. They are not related to diet, cosmetics, or how you clean your skin. Many persons ignore their milia; others find them a cosmetic nuisance and wish to have them removed.\nTreatment:\nThe milium is a small sac growing within the upper part of the skin. Because it is in the skin-and not on top of it- it can not be scratched, scraped or rubbed away. Milia can be removed by using a hypodermic needle to gently open the overlying skin and then flicking out the small sac. Some patients successfully “pop out” their milia with a sterile needle. However, most patients prefer to have a physician remove them’. If milia are large, I usually inject a local anesthetic (\nXylocaine/ Lidocaine) and then the milium can be carefully removed without discomfort. Small milia are usually removed without anesthesia because the sting of the anesthetic may be worse than the pinprick required to remove the milium.", "pred_label": "__label__POS", "pred_score_pos": 0.580877959728241}
{"content": "Be safe. Use the used litter only to fill holes; that's about it.\nThere are a lot of bloggers who demonstrate you CAN compost cat litter (wood and clay), growing even leafy ground crops like lettuce. But they have not tested their cats or their worked soil.\nMy property is a little wild, and I've spent a few years leveling out some of the larger dips and holes. I do this by digging up the topsoil (one foot down), filling it some, then returning the topsoil. If I need to relocate a lot of soil, I'll use a pick and dig a small pit on the edge of the property (so I immediately have topsoil + sand to mix with clean compost. I can then take my time filling that pit, and eventually cap it with topsoil. Note that if you do this with wood/paper litter, the decomposition will eventually cause the topsoil to \"sag\" so you may want to balance the paper/wood with clay, or mound a hill of topsoil in anticipation of settling.\nBeware that insufficient \"normal\" topsoil depth over this will present a walking hazard (boots punching through the topsoil into wet contaminated clay). Depending on your locale and laws, it MAY be considered some form of improper waste disposal so use sense and don't create a hazard for yourself or future owners of the property.\nI've only dug holes around the treeline as \"a\" I don't want to see a pit from the home windows, and \"b\" I don't want a mess where someone may walk over (however the freshly leveled space is OK for planting trees, flowers or other non-edible plants). 4\" of sandy topsoil followed by 2\" of mulch seems like a reasonable compromise for areas not normally walked on.", "pred_label": "__label__POS", "pred_score_pos": 0.6654122471809387}
{"content": "South Carolina, like many other states, is experiencing three co-occurring public health epidemics. The growing opioid crisis has significantly increased unsafe injection drug use, thereby increasing the prevalence of human immunodeficiency virus (HIV) and hepatitis C virus (HCV) through the sharing of contaminated syringes and needles. These synergistic epidemics not only are occurring at the same time, but have biological interactions among them that, together, exacerbate the prognosis and burden of the diseases.\nThe scientific literature contains extensive evidence that Syringe Services Programs (SSPs) reduce the transmission of HIV and HCV by providing sterile injection equipment and by linking users to multiple treatment and riskreduction services.\nThe CDC and HHS encourage states to submit HIV and HCV incidence and prevalence data profiles to them for review to determine if the need exists for SSPs to be established in their state. Upon demonstration of need, states are permitted to use federal funding for SSP staff, operations and supplies (though federal funds cannot be used to purchase syringes and needles). The CDC and HHS offer recommendations in their review regarding determination and consultation to states in implementing SSPs.\nIn January 2019, the South Carolina Department of Health and Environmental Control (DHEC) received verification from the CDC that South Carolina is at high-risk for HIV and HCV outbreaks due to increased opioid use and unsafe drug injection activities in the state. This CDC response not only emphasizes the need that exists in South Carolina to fund SSPs, but also provides recommendations for implementing this effective public health intervention to address these co-occurring epidemics. However, South Carolina law currently prohibits SSPs (Article 7, Sections 44-53-391 and 44-53-930 South Carolina Code of Laws). Section 44-53-391 makes it unlawful to “manufacture, possess, sell, or deliver…paraphernalia,” including hypodermic needles and syringes. It is further unlawful to provide “instructions, oral or written, with the [paraphernalia] concerning its use” or any other “descriptive materials accompanying the [paraphernalia] which explain or depict its use.” Section 44-53-930 requires hypodermic needles and syringes to be sold only by “registered pharmacists or registered assistant pharmacists through a permitted pharmacy” or by “persons lawfully selling veterinary medicines.", "pred_label": "__label__POS", "pred_score_pos": 0.9364454746246338}
{"content": "Infographic detailing CoST Honduras’s Sixth Assurance Report. This assurance process assessed three public-private partnership (PPP) infrastructure projects valued at US $277 million: it revealed an average data disclosure rate of 68.2% for the projects. This is the first and only CoST assurance process aimed solely at PPP projects in the region. Thus, the findings can be built on to establish a culture of disclosure as we have seen for the traditional projects included in CoST Honduras assurance.", "pred_label": "__label__POS", "pred_score_pos": 0.9988791942596436}
{"content": "2006-12-01\nWomen's organizations and democracy in South Africa: Contesting authority Publication Publication\nThe transition to democracy in South Africa was one of the defining events in twentieth-century political history. The South African women's movement is one of the most celebrated on the African continent. Shireen Hassim examines interactions between the two as she explores the gendered nature of liberation and regime change. Her work reveals how women's political organizations both shaped and were shaped by the broader democratic movement. Alternately asserting their political independence and giving precedence to the democratic movement as a whole, women activists proved flexible and remarkably successful in influencing policy. At the same time, their feminism was profoundly shaped by the context of democratic and nationalist ideologies. In reading the last twenty-five years of South African history through a feminist framework, Hassim offers fresh insights into the interactions between civil society, political parties, and the state. Hassim boldly confronts sensitive issues such as the tensions between autonomy and political dependency in feminists' engagement with the African National Congress (ANC) and other democratic movements, and black-white relations within women's organizations. She offers a historically informed discussion of the challenges facing feminist activists during a time of nationalist struggle and democratization.\nAdditional Metadata\nHassim, S. (2006). Women's organizations and democracy in South Africa: Contesting authority.\nWomen's Organizations and Democracy in South Africa: Contesting Authority, 1–355.", "pred_label": "__label__POS", "pred_score_pos": 0.9896472096443176}
{"content": "Abstrakt\nImpact-generated hydrothermal systems have been suggested as favourable environments for deep microbial ecosystems on Earth, and possibly beyond. Fossil evidence from a handful of impact craters worldwide have been used to support this notion. However, as always with mineralized remains of microorganisms in crystalline rock, certain time constraints with respect to the ecosystems and their subsequent fossilization are difficult to obtain. Here we re-evaluate previously described fungal fossils from the Lockne crater (458 Ma), Sweden. Based on in-situ Rb/Sr dating of secondary calcite-albite-feldspar (356.6 ± 6.7 Ma) we conclude that the fungal colonization took place at least 100 Myr after the impact event, thus long after the impact-induced hydrothermal activity ceased. We also present microscale stable isotope data of\n13C-enriched calcite suggesting the presence of methanogens contemporary with the fungi. Thus, the Lockne fungi fossils are not, as previously thought, related to the impact event, but nevertheless have colonized fractures that may have been formed or were reactivated by the impact. Instead, the Lockne fossils show similar features as recent findings of ancient microbial remains elsewhere in the fractured Swedish Precambrian basement and may thus represent a more general feature in this scarcely explored habitat than previously known.", "pred_label": "__label__POS", "pred_score_pos": 0.9758510589599609}
{"content": "A functional varient in microRNA-146a is associated with risk of esophageal squamous cell carcinoma in Chinese Han\nHong Guo, Kai Wang, Gang Xiong, Huamei Hu, Dongmei Wang, Xueqing Xu, Xingying Guan, Kang Yang, Yun Bai\nFamilial Cancer 2010, 9 (4): 599-603\n20680470\nMicroRNAs are a new class of non-proteincoding, small RNAs that function as tumor suppressors or oncogenes. They participate in diverse biological pathways and function as gene regulators. A G>C polymorphism (rs2910164), which is located in the sequence of miR-146a precursor, results in a change from G:U to C:U in its stem region. However, it remains largely unknown whether this single nucleotide polymorphism (SNP) may alter esophageal squamous cell carcinoma (ESCC) susceptibility. In the current study, we evaluated association between rs2910164 and ESCC susceptibility in a case-control study of 444 sporadic ESCC patients and 468 matched cancer-free controls in a Chinese Han population. Compared with rs2910164 variant genotype CC, genotype GG was associated with increased risk of ESCC (Odds Ratio, 2.39, 95% Confidence Interval, 1.36-4.20). In the smokers, the risk of rs2910164 GG genotype was more notable (Odds Ratio, 3.17, 95% Confidence Interval, 1.71-4.46). In the stratification analyses, we also found there was a strong correlation between rs2910164 C/G variant and the clinical TNM stage (P < 0.01). These findings suggest that this functional SNP in pre-miR-146a could contribute to ESCC susceptibility and clinical outcome.\nFind Full Text Links for this Article\nRelated Papers", "pred_label": "__label__POS", "pred_score_pos": 0.652045488357544}
{"content": "The growing uranium supply deficit, currently being accelerated by COVID-19 pandemic related production cuts, has seen the price for uranium skyrocket – making it the world’s best-performing major commodity right now.\nWith the suspension of operations at four notable uranium mines in March and April, the spot price has surged to US$33/lb in May from $24/lb at the start of the year on the back of this tightening global supply.\nThis situation is unlikely to change in the near future, which could drive the price higher as long-term demand is set to continue, says Toronto-based Red Cloud Securities. CHANTELLE KOTZE reports.\nThe four uranium mines in question include the Cigar Lake mine in Canada, suspended on 23 March, the Rössing and Husab mines in Namibia suspended on 28 March and Kazakhstan-based Kazatomprom’s suspension of operations on 7 April.\nRed Cloud Securities (formerly Red Cloud Klondike Strike), a modern day, next generation brokerage firm focused on providing unique and innovative financing alternatives, growth opportunities and market exposure for mining companies, recently hosted a webinar to explore the drivers behind the uranium bull market further.\nFor the rest of this article:\nhttps://www.miningreview.com/uranium/uranium-a-global-bull-market-is-under-way-due-to-covid-19/", "pred_label": "__label__POS", "pred_score_pos": 0.6429937481880188}
{"content": "Abstract\nDiabetes mellitus is associated with abnormalities in central noradrenergic dynamics, a system that appears to be involved in the regulation of nociception in both humans and experimental animals. To this end, we investigated the responsiveness of nociceptive threshold to the actions of clonidine (an α\n2-adrenoreceptor agonist) and yohimbine (an α 2-adrenoreceptor antagonist) during diabetes. The induction of diabetes was achieved by the administration of streptozotocin (STZ) (55 mg/kg, intravenously). Nociceptive threshold, as indicated by the tail-flick latency of the tail immersion test, was progressively elevated as a function of the duration of diabetes. Systemic administration of clonidine and yohimbine respectively produced dose-dependent analgesic and hyperalgesic effects in control animals. Both of these phenomena were impaired in chronically diabetic animals. In contrast, insulin-treated diabetics displayed supersensitivity to clonidine's antinociceptive effect, especially at low doses. Acute hyperglycemia did not interfere with the α 2-agonist-mediated elevation in nociceptive threshold. Attenuation in clonidine antinociceptive effect was also observed following its intrathecal administration to diabetic animals. Overall, these data suggest that the impaired responsiveness of diabetic rats might be due to a central α 2-adrenoreceptor desensitization and/or biochemical defect in the postreceptor events. Keywords clonidine experimental diabetes insulin nociception yohimbine", "pred_label": "__label__POS", "pred_score_pos": 0.8695009350776672}
{"content": "Microheterogeneity-induced conduction slowing and wavefront collisions govern macroscopic conduction behavior: A computational and experimental study.\nPublished\nJournal Article\nThe incidence of cardiac arrhythmias is known to be associated with tissue heterogeneities including fibrosis. However, the impact of microscopic structural heterogeneities on conduction in excitable tissues remains poorly understood. In this study, we investigated how acellular microheterogeneities affect macroscopic conduction under conditions of normal and reduced excitability by utilizing a novel platform of paired in vitro and in silico studies to examine the mechanisms of conduction. Regular patterns of nonconductive micro-obstacles were created in confluent monolayers of the previously described engineered-excitable Ex293 cell line. Increasing the relative ratio of obstacle size to intra-obstacle strand width resulted in significant conduction slowing up to 23.6% and a significant increase in wavefront curvature anisotropy, a measure of spatial variation in wavefront shape. Changes in bulk electrical conductivity and in path tortuosity were insufficient to explain these observed macroscopic changes. Rather, microscale behaviors including local conduction slowing due to microscale branching, and conduction acceleration due to wavefront merging were shown to contribute to macroscopic phenomena. Conditions of reduced excitability led to further conduction slowing and a reversal of wavefront curvature anisotropy due to spatially non-uniform effects on microscopic slowing and acceleration. This unique experimental and computation platform provided critical mechanistic insights in the impact of microscopic heterogeneities on macroscopic conduction, pertinent to settings of fibrotic heart disease.\nFull Text Duke Authors Cited Authors Gokhale, TA; Asfour, H; Verma, S; Bursac, N; Henriquez, CS Published Date Published In Volume / Issue Start / End Page PubMed ID Pubmed Central ID Electronic International Standard Serial Number (EISSN) International Standard Serial Number (ISSN) Digital Object Identifier (DOI) 10.1371/journal.pcbi.1006276 Language", "pred_label": "__label__POS", "pred_score_pos": 0.949360728263855}
{"content": "Contact Erin Carmona at ecarmona@littler.com\nThe experts agree that a recession is likely in 2020, ending the longest period of economic expansion in U.S. history. One of the inevitable byproducts when the economy retracts is the need of many businesses to conduct reductions-in-force. However, most HR professionals have not had to manage a layoff process for many years. For this reason, Littler has joined with Keystone Partners, a leading Career Management provider in New England, to design a session that will help you brush off the cobwebs. The speakers will provide a practical checklist of legal, employee and organizational support issues companies need to consider when planning a reduction-in-force.\nRegistration and Breakfast: 8:00 - 8:30 am Program: 8:30 - 10:30 am", "pred_label": "__label__POS", "pred_score_pos": 0.5732395648956299}
{"content": "I once spoke with a woman who bristled at my suggestion that she introduce her vibrator to her sexual partner. I inquired as to the source of her objection. She explained that she was afraid to hurt her partner’s feelings; that it might lead to feelings of inadequacy.\nShe was deeply attracted to this person, and she described their relationship as supportive and loving. Still, she was afraid that the idea of incorporating a toy during sex would bruise his ego. I acknowledged this and told her the decision was entirely up to her. “I just have one follow-up question: if he uses a medication that enhances his sexual wellness and his connection to you, why is a vibrator any different?” She smiled and said, “point well taken.”\nDoctor of Human Sexuality, Emily Morse, addresses this exact topic in her latest blog entitled “Is It Okay to Always Use a Clitoral Vibe?”\nIf you are curious about raising the topic with your partner or want guidance regarding the myriad of sex toy offerings, check out our list of recommended products.", "pred_label": "__label__POS", "pred_score_pos": 0.9940086603164673}
{"content": "How does the automotive industry move towards Automated Driving Systems safely? This new technology is rightly seen as a sea change for road safety. However, new and emerging systems require heightened levels of vigilance from regulators, vehicle manufacturers and users.\nThatcham Research and the ABI have authored a comprehensive report setting out 12 key principles to ensure a safe transition period between Assisted and Automated Driving. The video [right] introduces some of the Automated Driving Systems that we can expect to see on our roads from 2021.", "pred_label": "__label__POS", "pred_score_pos": 0.9561031460762024}
{"content": "And that’s good. by Ronald Bailey Reason.com\nPresident Donald Trump has been touting chloroquine and hydroxychloroquine since March as effective treatments for COVID-19. He even took hydroxychloroquine as a prophylactic measure for two weeks in May.\nLast week, when the president was hospitalized for a COVID-19 infection, his physicians listed the medications with which he is being treated. Hydroxychloroquine is notable by its absence.\nInstead, the president has been aggressively treated with Regeneron Pharmaceuticals’ polyclonal antibodies. This combination of two monoclonal antibodies aims to block the coronarvirus from infecting cells, providing extra time for patients’ immune systems to ramp up their own natural defenses against the virus. While the treatment is still in clinical trials, preliminary reports suggest that it does substantially help to alleviate COVID-19 symptoms.", "pred_label": "__label__POS", "pred_score_pos": 0.9830540418624878}
{"content": "I learned a new way of looking at policies recently. The standard ways that you do things at your workplace, how you treat and manage your employees, your day-to-day practices—these are your HR policies and procedures, regardless of whether you've written them down or not.\nHR policies and procedures\nDoes your organization have an employee handbook? Are you thinking about creating one? Do employees and managers have questions or conflicting beliefs about your current handbook? The following overview discusses what an employee handbook is not, highlights the key purpose of an effective handbook and outlines some tips for effective employee handbooks.\nOn April 29, 2014, Bill 21, the Employment Standards Amendments Act (Leaves to Help Families), 2014, received royal assent and will come into force six months after assent, on October 29, 2014.", "pred_label": "__label__POS", "pred_score_pos": 0.5294359922409058}
{"content": "With the increasing popularity of embedded and mobile devices, ARM is becoming the dominant architecture in them. Accordingly, there is a pressing need to perform security assessments to these devices. Due to the fragmentation, it is an ongoing research question to dynamically run the systems of these devices (or the firmware) in an emulated environment. Mainly due to this, the static analysis approach is still a commonly used way. In particular, existing works usually leverage off-the-shelf disassembly tools to disassemble stripped (ARM) binaries, and assume that reliably disassembling them and identifying functions are solved problems. However, whether this assumption holds for real world ARM binaries is unknown.\nIn this paper, we conduct a comprehensive study on ARM disassembly tools. Specifically, we build 1,896 ARM binaries (including 248 obfuscated ones) with different compilers, compiling options, and obfuscation methods. Using these binaries, we then evaluate eight state-of-the-art ARM disassembly tools (including both commercial and noncommercial ones) on their capabilities to locate instruction and function boundaries. These two primitives are fundamental ones and could be leveraged to build other primitives. Based on our evaluation, we present observations that were not systematically summarized and/or confirmed previously. For instance, we find that the existence of both the ARM and the Thumb instruction sets, and the reuse of the BL instruction for both direct function call and direct branch bring serious challenges to disassembly tools. Our evaluation sheds light on the limitations of the state-of-the-art disassembly tools and points out potential directions to improve them. To engage the community, we will publicly release the compiled ARM binaries, the retrieved ground truth, and the result.\nWed 22 Jul Times are displayed in time zone: Tijuana, Baja California change Tijuana, Baja Californiachange\n10:50 - 11:10 Talk\nTechnical Papers\nYifei Xu, Zhengzi Xu, Bihuan ChenFudan University, Fu Song, Yang LiuNanyang Technological University, Singapore, Ting LiuXi'an Jiaotong UniversityDOI Media Attached\n11:10 - 11:30 Talk\nTechnical Papers\nGeorge FourtounisUniversity of Athens, Leonidas TriantafyllouUniversity of Athens, Yannis SmaragdakisUniversity of Athens, GreeceDOI Media Attached\n11:30 - 11:50 Talk\nTechnical Papers\nMuhui Jiang, Yajin ZhouZhejiang University, Xiapu LuoThe Hong Kong Polytechnic University, Ruoyu Wang, Yang LiuNanyang Technological University, Singapore, Kui RenDOI", "pred_label": "__label__POS", "pred_score_pos": 0.6735055446624756}
{"content": "UC Irvine Kidney function, proteinuria and breast arterial calcification in women without clinical cardiovascular disease: The MINERVA study. Author(s): Parikh, Rishi V Iribarren, Carlos Lee, Catherine Levine-Hall, Tory Tan, Thida C Sanchez, Gabriela Ding, Huanjun Bidgoli, Fatemeh Azamian Molloi, Sabee Go, Alan S et al. Published Web Locationhttps://doi.org/10.1371/journal.pone.0210973 Abstract\nBACKGROUND:Breast arterial calcification (BAC) may be a predictor of cardiovascular events and is highly prevalent in persons with end-stage kidney disease. However, few studies to date have examined the association between mild-to-moderate kidney function and proteinuria with BAC. METHODS:We prospectively enrolled women with no prior cardiovascular disease aged 60 to 79 years undergoing mammography screening at Kaiser Permanente Northern California between 10/24/2012 and 2/13/2015. Urine albumin-to-creatinine ratio (uACR), along with specific laboratory, demographic, and medical data, were measured at the baseline visit. Baseline estimated glomerular filtration rate (eGFR), medication history, and other comorbidities were identified from self-report and/or electronic medical records. BAC presence and gradation (mass) was measured by digital quantification of full-field mammograms. RESULTS:Among 3,507 participants, 24.5% were aged ≥70 years, 63.5% were white, 7.5% had eGFR <60 ml/min/1.73m2, with 85.7% having uACR ≥30 mg/g and 3.3% having uACR ≥300 mg/g. The prevalence of any measured BAC (>0 mg) was 27.9%. Neither uACR ≥30 mg/g nor uACR ≥300 were significantly associated with BAC in crude or multivariable analyses. Reduced eGFR was associated with BAC in univariate analyses (odds ratio 1.53, 95% CI: 1.18-2.00), but the association was no longer significant after adjustment for potential confounders. Results were similar in various sensitivity analyses that used different BAC thresholds or analytic approaches. CONCLUSIONS:Among women without cardiovascular disease undergoing mammography screening, reduced eGFR and albuminuria were not significantly associated with BAC.", "pred_label": "__label__POS", "pred_score_pos": 0.6789568662643433}
{"content": "Mumbai (Maharashtra) [India], November 17 (ANI/NewsVoir): Trifo, a California-based AI home robot company, has been one of the best-selling brands on Amazon for the last three months.\nTrifo managed to sell 1500 units of its robot vacuums every month, which is a significant achievement considering it's a new entrant in the Indian market. Outstanding advanced features along with the scrumptious festive deals offered by Trifo are the reasons behind the record sales.\nAs part of the festive extravaganza, Trifo's recently launched Emma series is available at an attractive price of Rs 19,990 (MRP: Rs 32,999). Whereas a month-old Trifo Max and Trifo Ironpie are available at a discounted price of Rs 17,990 (MRP: Rs 39,999) and Rs 23,990 (MRP: Rs 32,999), respectively.\nWhen the festive season is the best time to invest in a house cleaning robot, the company will continue this sale till November 30, 2020.\nThe Pet-versions of Trifo Max and Trifo Emma, featuring a more powerful suction of 4,000 Pa, are hot selling models on Amazon. They are ideal for pet owners at home to manage animal hair and pick up bigger dust particles in a single pass.\nTrifo has partnered with Mumbai-based Cambium Retail to foray into India, offering a product portfolio ranging from entry-level to high-end models. Currently, the three models are sold through e-commerce websites.\n\"The love and acceptance we have received from customers in India are overwhelming. Gaining good traction on online platforms has reinforced our commitment to the country. We are aggressively planning to strengthen our offline retail channels, along with introducing more products and deepening our presence in Tier II and Tier III cities,\" said Zhe Zhang, Founder and CEO of the company, while speaking about strengthening Trifo's distribution network in India.\nTrifo robot cleaners are smart and reliable, offering excellent features under the hood. One of the key features is the smart navigation system, the patented Trifo Intelligent Robotics Vision System (TIRVS), which continuously learns about the home environment and improves cleaning routes.\nApart from the core function of cleaning, Trifo Max can also be used for home monitoring and security, using the primary camera for both navigation and surveillance.\n\"Our continuous endeavor is to create and deliver products that offer great value to customers. We strive to offer the latest technologies and revolutionary products that enhance people's lives and let them focus on what's important,\" Zhang added.\nTrifo cleaners offer long battery life that gives an impressive runtime of up to 120 minutes, and will automatically return to the charging base when the cleaning is finished. All three Trifo models support Wi-Fi connectivity and are compatible with Amazon Alexa for voice commands. The vacuum cleaners can also be controlled using the Trifo Home mobile app to start, stop, and schedule cleaning jobs, get notified when finished, adjust the suction power, and more.\nThe much-anticipated festive season is when Indian families take up the tedious house cleaning process. Trifo aims to make this occasion special with lucrative deals and extending a tech-driven helping hand, thereby enabling a wide range of products more accessible.\nFounded in 2016 and headquartered in Santa Clara, California, Trifo is a full-stack AI home robot company. Focusing on indoor home environments, Trifo creates end-to-end integrated hardware/software systems with sensing, perception and decision-making capabilities.\nThese robots help people live better lives by perceiving physics, geometry and semantics of home environments, naturally communicating with humans and continuously learning new skills with advanced AI technologies.\nTrifo's vision is to build a family of home robots that enhance people's lives and let them focus on what's important. Named after the mighty clover, Trifolium repens, Trifo works hard to improve people's well-being. The company is dedicated to developing home robots that help families obtain the optimal balance between family, work and personal life.\nTrifo has earned more than 50 patents and filed for more than 70 additional patents globally. Trifo's proprietary algorithms have been published at top robotics conferences such as ICRA and IROS.\nThe company has raised over USD 26 million from various venture capital funds, including Walden International, Matrix Partners and Samsung Ventures.\nThis story is provided by NewsVoir. ANI will not be responsible in any way for the content of this article. (ANI/NewsVoir)", "pred_label": "__label__POS", "pred_score_pos": 0.5070440769195557}
{"content": "Abstract\nIn biodiversity offsetting, developers are permitted to degrade an ecosystem and its species in exchange for “offsetting” the damage elsewhere. The practice, albeit controversial, is rapidly spreading as a proposed win-win solution that allows biodiversity and development to coexist. In this article, I explore best practices for how the U.S., Australia, the U.K., and South Africa structure their laws to turn species and their habitats into fungible commodities to be traded like Pokémon cards.\nI analyze how different jurisdictions regulate the\ntemporal dimension of biodiversity offsetting: when must offset requirements be completed (e.g., before or after the original destruction is allowed), and for how long to must the offset be maintained? I examine the spatial requirements: e.g., how far from the original destruction must or may the offset be? I look at the type of trades that are allowed: for example, must the “replacement” entity be the same as the entity that is destroyed or degraded? Finally, I examine who must do what to make sure the offset is sustained.\nIn analyzing how jurisdictions arrange these variables, I provide examples that others might or might not wish to adapt. Furthermore, how these variables are legally mandated helps us understand how a nation, a state, or a community understands its relationship with the natural world, and what that portends for the future of human/non-human interactions. How polities strike that balance will be reflected by the specific choices they make not only to allow offsetting in the first place, but in the ways they stack the variables to ensure (or not) species and ecosystem viability in the short term and long term. I conclude by explaining how well-structured, carefully implemented and monitored biodiversity offsetting could be part of our conservation toolkit for the Anthropocene era. But to implement biodiversity offsetting in a deeply equitable way will be expensive, difficult, and require a cadre of dedicated stakeholders committed to sustainable human and nonhuman communities.", "pred_label": "__label__POS", "pred_score_pos": 0.8317921161651611}
{"content": "For patients with crooked or crowded teeth, metal braces may seem like the only option available. However, we can often use cosmetic treatments to correct uneven smiles without the use of metal braces. If you live in the Urbandale, IA area, Dr. Lawson and her teeth can help you straighten your teeth with life-like dental veneers.\nThe Health Risks of Poor Alignment\nHow does an uneven smile impact your overall oral health? Crooked or crowded teeth provide nooks and crannies for food particles to become trapped. These can remain behind even if you brush and floss. Soon, bacteria break down the particles and in the process, lead to the onset of tooth decay and gum disease. Misalignment also leads to pressure on the jaw joints, which can make TMJ disorder and bruxism more likely. By correcting the issue, you can enjoy a healthier smile.\nVeneers as Instant Orthodontics\nWhat if we could use porcelain veneers instead of braces? Veneers fit over the front and sides of a tooth, allowing us to completely alter the appearance of the tooth. Which means we can place these restorations and correct the appearance of minor misalignment, helping you achieve a stunning new smile without the use of orthodontics. We can also use them to repair minor damage, close gaps between teeth, and mask permanent teeth stains.\nThe MTM® System\nWe can also use the Minor Tooth Movement system (MTM Clear Aligners). Instead of metal brackets and wires, we create a series of clear plastic aligners, which fit comfortably and help shift your teeth to optimal positions. In a matter of months, we can use these aligners to help improve the alignment of your smile. The aligners can also be removed before you brush and floss or eat, meaning you don’t need to change up your routine or avoid certain foods. If you have any questions about the MTM system or about our dental veneers, then contact our office today. We want to help you enjoy a beautiful smile!\nDo You Need Orthodontic Treatment?\nDr. Lawson and our team can address misalignment with cosmetic alternatives to regular orthodontics. To learn more, schedule a consultation by calling our sleep dentistry office in Urbandale, IA, at 515-278-4366.", "pred_label": "__label__POS", "pred_score_pos": 0.7971896529197693}
{"content": "Abstract\nIn order to understand how nanoparticles (NPs < 100 nm) interact with cellular systems, potentially causing adverse effects, it is important to be able to detect and localize them within cells. Due to the small size of NPs, transmission electron microscopy (TEM) is an appropriate technique to use for visualizing NPs inside cells, since light microscopy fails to resolve them at a single particle level. However, the presence of other cellular and non-cellular nano-sized structures in TEM cell samples, which may resemble NPs in size, morphology and electron density, can obstruct the precise intracellular identification of NPs. Therefore, elemental analysis is recommended to confirm the presence of NPs inside the cell. The present study highlights the necessity to perform elemental analysis, specifically energy filtering TEM, to confirm intracellular NP localization using the example of quantum dots (QDs). Recently, QDs have gained increased attention due to their fluorescent characteristics, and possible applications for biomedical imaging have been suggested. Nevertheless, potential adverse effects cannot be excluded and some studies point to a correlation between intracellular particle localization and toxic effects.\nJ774.A1 murine macrophage-like cells were exposed to NH2 polyethylene (PEG) QDs and elemental co-localization analysis of two elements present in the QDs (sulfur and cadmium) was performed on putative intracellular QDs with electron spectroscopic imaging (ESI). Both elements were shown on a single particle level and QDs were confirmed to be located inside intracellular vesicles. Nevertheless, ESI analysis showed that not all nano-sized structures, initially identified as QDs, were confirmed. This observation emphasizes the necessity to perform elemental analysis when investigating intracellular NP localization using TEM.", "pred_label": "__label__POS", "pred_score_pos": 0.812899649143219}
{"content": "There was a breakthrough in negotiations over the weekend: House and Senate negotiators are now free to write a final, House-Senate spending bill for HUD. This bill includes final funding amounts for HUD's Homeless Assistance.\nWe urge you to reach out to your Representative and Senators before the Thanksgiving holiday, asking them to contact Appropriations Leadership with this message: Congress needs to pass a final HUD spending bill that includes $3 billion for Homeless Assistance.\nWe don't know whether Congress will pass that bill in December, or if it will be pushed until next year. But we do know that HUD's Homeless Assistance programs need a substatial increase, and the current negotiations will set the final amount. We need your advocacy now.\nMake your voices heard, and share with Congress the need for more funding for homeless assistance. We have tools to help draft an email here.", "pred_label": "__label__POS", "pred_score_pos": 0.9744243025779724}
{"content": "Biography\nHolly Sutton guides businesses, compensation committees, and boards in managing the critical employment matters they face, with an eye toward both practical solutions and risk management. A theoretically flawless solution that is unworkable is of no value—Holly provides approaches that work in the real business world in which her clients operate. In this role, she frequently advises on policies or measures at the planning stage—proactive involvement in employment issues is almost always preferable to devising responses\nex post facto. Holly is the chair of Farella's Employment Practice.\nHolly counsels clients on the design and implementation of employment policies and practices to minimize the risk of employment litigation, and ensure compliance with applicable law. Specific areas in which Holly advises her clients include personnel policies, wage and hour laws, EEO compliance, hiring and termination practices, harassment and discrimination investigations, non-competition clauses, conflict of interest, and trade secret matters. She has worked with clients in a range of industries, including media, insurance, wine, agriculture, technology, retail, banking, construction, manufacturing, cannabis, and professional services.\nBy developing innovative strategies that are grounded in her deep knowledge of employment law, yet carefully tailored to each client’s individual circumstances, Holly helps her clients navigate particularly high-risk scenarios and challenging situations, including reductions in force, realignment of workforces, mergers, acquisitions, and divestitures.\nHolly provides carefully tailored advice, focusing on the specific and unique facts of each situation, and partners with her clients to develop strategies that best protect against claims and disruptions, while working within the realities of day-to-day operation.\nIn addition to employment-related counseling, Holly also defends clients in wrongful termination and employment discrimination actions, including claims for race, age, sex, disability, and pregnancy discrimination. She has advocated in state and federal courts as well as various administrative forums, including single plaintiff, multi-plaintiff, and class action matters.\nShe has also defended cases involving trade secrets, accommodation, and employee solicitation issues. She has extensive experience in all facets of contractual arbitration, and has defended government investigations, resulting in dismissal of claims.\nAn essential part of her role as a trusted advisor on employment matters is ensuring that her clients are kept abreast of the latest developments in employment law— an ever-changing field. She’s a frequent speaker, author, panelist, and media source, and in addition to advising on the current state of the law, frequently counsels on upcoming changes and trends that will affect her client’s business, strategy and workforce. For example, the gig economy freelancing and contract employees present unique employment challenges. By staying ahead of trends in business, Holly helps her clients compete and succeed as well.\nDistinctions Labor & Employment Star, Benchmark Litigation(2019-2021) Memberships and Affiliations Member, Employment Rights & Responsibilities Committee, ABA Labor & Employment Law Section", "pred_label": "__label__POS", "pred_score_pos": 0.5218705534934998}
{"content": "Conservation Plan\nThe Land Trust for Tennessee released a first-of-its kind strategic conservation plan in September 2019 to accelerate and guide our work across the state, and highlight the importance of land conservation in Tennessee.\nThe plan, titled “Forever Tennessee,” outlines a focused vision for The Land Trust to conserve farms, forests, historic sites, recreation areas, wildlife habitat, and scenic landscapes in 10 Conservation Opportunity Regions throughout the state. The aim is to strategically and proactively conserve land, both public and private, to support local economies, public health, historic preservation, biodiversity, sense of place, and more. Our commitment is to increase the quality, pace, and impact of land conservation across Tennessee.\nCHARTING A PATH FORWARD\nTo complete Forever Tennessee, we compiled over 25 different datasets from a variety of authoritative sources, including state and federal government entities, scientific research organizations, and other conservation groups.\nThis allowed us to map conservation resources across Tennessee—such as fertile soils for farming, diverse wildlife habitat, and historic landscapes—and identify areas with the highest concentration of these resources. We then analyzed census data and population growth projections to prioritize places in most immediate need of our work.\nDEFINING OUR CONSERVATION OPPORTUNITY REGIONS (CORS)\nOnce the data was gathered and analyzed, we finalized 10 Conservation Opportunity Regions (CORs) across Tennessee where we will focus our proactive work moving forward. These areas represent a range of land resources, are distributed across the state, and are within our capacity to implement conservation programs.\nThe CORs allow us to focus on the highest conservation-value land while simultaneously increasing our base of support with funders and community members. As a statewide land trust, we will remain responsive to landowners outside of the CORs, but our data model better enables our decision-making on an individual project basis.\nForever Tennessee lays a foundation that will revolutionize the way we work: to direct our entire team on where to spend time and funding, and to help us choose the best possible conservation projects to maximize our mission.", "pred_label": "__label__POS", "pred_score_pos": 0.7225750684738159}
{"content": "It is imperative for us to interact and connect with people around. After all, man is a social animal. I realised the importance of interactions and connections early in life. As a child, I always found it easy to make friends. The boy from the corner house, who loved cricket and spoke very little, was my friend; the shy girl from dance class; the maid’s daughter who occasionally came home–all were my friends. These people brought so much happiness to my life.\nThings change as you grow. When I was sent to a boarding school, I found a bigger turf to make friends. As children and teenagers, it is easier to make friends. But as an adult, I have observed that some of my peers find it hard to befriend strangers. I, on the other hand, make friends wherever I go–in the lift, at the flea market, on a solo trip, in the parking lot… There is some amount of extroversion that is needed, I agree. But if you can let go of your inhibitions, you too might find yourself forging strong friendships.\nFrom my experience, I have learnt two things–friendships with strangers can be life-changing and they may or may not last forever. But for the fleeting moments they last, they are worthwhile. Let me try and convince you with these three encounters I had and how they brought memorable friendships into my life.\nGirl at the bus stop\nHer face was familiar. I had seen her earlier in the same stop waiting for a bus, probably to go to work. We had only exchanged glances a long time ago. I had thought she was haughty. Though we took the same bus nearly every day, we never talked. But one day, it was just the two of us at the stop. The bus that had taken its own sweet time to arrive looked like a heavily pregnant dog about to pop. At that instant, both of us looked at each other with a hopeless smile. This was not the first time we had witnessed something like this, but this was the first time both of us muttered ‘Not again!’ in unison. We broke into a laugh. We had been strangers until then. But something about that laughter made us feel like we had known each other forever, and it was the beginning of a beautiful friendship. We don’t meet every day, but when we do, we have a hearty chat about life, death, and everything in between. Looking back, I realise first impressions are not always right.", "pred_label": "__label__POS", "pred_score_pos": 0.5287158489227295}
{"content": "People who experience homelessness in England are 60 times more likely to visit A&E in a year compared with the general population. This is largely due to the difficulty they have in registering at a GP surgery, with people often wrongly turned away due to lack of proof of address or identification.\nTo help address this, Groundswell and the London Homeless Health Programme (LHHP) have produced ‘My Right to Healthcare’ cards for people experiencing homelessness which explain that this population have a right to register with GP surgery", "pred_label": "__label__POS", "pred_score_pos": 0.9442740678787231}
{"content": "Survey of fixed-income managers shows rising preference for EM debt and high-yield credit\nDespite holding generally bearish outlooks for the global economy, fixed-income managers appear to be ratcheting up their risk tolerance, according to a new survey.\nIn a newly unveiled Q4 poll of fixed-income managers, Russell Investments found that 50% expected the global economy to return to pre-pandemic levels by the end of 2021, while 48% expect it to happen in 2022 at the soonest.\nDespite that bearish outlook, the respondents appeared to be shifting away from the safety of higher-rated fixed-income instruments. The proportion of respondents choosing investment-grade credit as the most attractive out of 10 asset classes for risk-adjusted returns declined over the quarter from 40% to 20%.\nIn contrast, those selecting emerging-market debt rose 10 percentage points to 15%. Views on local-currency EM debt grew more constructive as 60% of respondents shared expectations of slight positive performance in the next 12 months, compared to last quarter when 32% of respondents predicted it to be a detractor in the coming 12-month period.\nAppetite for high-yield credit also rose by eight percentage points, reaching 23% in Q4. Forty-five per cent of respondents expect an improvement in the fundamentals of high-yield corporates, a massive sentiment shift from last quarter when 100% predicted that they would deteriorate. Just over half (52%) believed U.S. high-yield bonds would offer the best risk-adjusted return in the next 12 months, with energy, retail, and healthcare being areas where credit risk may not be correctly priced in.\n“While a second wave of COVID-19 infections and the speed of global economic recovery remain as their top concerns for the fourth quarter, fixed income managers seem to be less worried about the depth of the global recession,” Adam Smears, senior director, Investment Research-Fixed Income at Russell Investments, said in a statement. “Instead, they appear more focused on the pandemic’s financial impact on specific companies.”\nThe survey also found an overwhelming belief (96%) that the U.S. Federal Reserve will not push interest rates into negative territory. Nearly two thirds (63%) anticipated that U.S. inflation will stay within the 1.5% to 2% range over the next 12 months, and 53% predicted the Fed will hit its 2% inflation target over the next decade.", "pred_label": "__label__POS", "pred_score_pos": 0.6005533337593079}
{"content": "Peking Man was the name given to the fossil remains of a Homo Erectus, and an extinct hominid believed to be an ancestor of modern humans. The remains got their name after the city of Peking, China (modern-day Beijing) where they were unearthed by archeologists between 1923 and 1928. The fossil remains are so interesting among palaeontologists because they disappeared during the Second World War. While the location of the original fossils is a mystery, well-detailed descriptions and casts of the fossils are in excellent condition.\nDiscovery\nThe Zhoukoudian cave system, where Peking Man was unearthed, was designated as a World Heritage Site by UNESCO in 1987. The discovery of the Peking Man’s fossil was gradual, starting with the unearthing of a fossilized tooth in 1923 by Otto Zdansky, a palaeontologist from Austria, with other subsequent significant discoveries of teeth, a jaw, and skull, being made between 1923 and 1928.\nAncestry\nRenowned 20th-century palaeontologist Franz Weidenreich, once made it public that he believed Peking Man was the Chinese people’s ancestor, basing his argument on his widely-accepted 1946 multiregional theory of human evolution. Franz Weidenreich had studied the fossil remains of the hominid for several years, making his findings relevant and credible. However, many Chinese scholars disputed Franz’s claim, stating that the remains of Peking Man resembled Europeans than modern Chinese. Nonetheless, scholars and palaeontologists agree that Peking Man is most likely a progenitor of modern humans.\nDisappearance\nThe remains of Peking Man were initially housed at Peking’s Union Medical College, where intensive studies were conducted. The excavations of the fossils were halted in 1937 after Japan invaded China during the Second World War. By 1941, Beijing (Peking) had fallen under Japanese control, but it is believed that before Japanese forces could reach Union Medical College, the remains of Peking Man were stored in two big crates and transferred to the Chinese port of Qinhuangdao by US Marines, where security was guaranteed from the nearby American base, Camp Holcomb. The intention was to then transport the fossils to New York at the American Museum of Natural History through a ship. The fossils disappeared during their marine journey to the United States, never to be found again even after a reward amounting to $5,000 towards its recovery was offered by an American financier in 1972. Recently, the Chinese government established a committee to search for the fossils, which was instituted at the time the world was marking the 60th anniversary of the end of WWII in 2005. All that remains of Peking Man are four of its original teeth, which are housed at Uppsala University’s Paleontological Museum.\nExplanation of the Disappearance\nThe vanishing of the remains of Peking Man has spurned numerous theories, attempting to explain the disappearance. One theory has it that the American ship in which the remains were transported, was sunk before its arrival in the United States. Another theory states that the remains did not leave China but were grounded up to make traditional medicine. One somewhat controversial one state that the remains were not transported in an American ship, but were instead transported in a Japanese vessel destined for Japan.", "pred_label": "__label__POS", "pred_score_pos": 0.9258267283439636}
{"content": "Electrocatalysts have shown promise as a way to efficiently convert waste CO2 into clean fuels, but the mechanisms by which they operate are often unknown making it hard for researchers to design new ones in a rational manner. New research demonstrates a laser-based spectroscopy technique that can be used to study the electrochemical reduction of CO2 in-situ and provide much-needed insights into these complex chemical pathways.", "pred_label": "__label__POS", "pred_score_pos": 0.9948066473007202}
{"content": "Article (Published version) (3.3 MB) - Limited access to UNIGE\nHighlights\nTitle\nCharacterization of cardiac dysfunction in sepsis: an ongoing challenge Authors Published in Shock. 2014, vol. 41, no. 1, p. 12-24 Abstract Sepsis-induced cardiomyopathy (SIC), which is a common morbid condition, occurs in patients with severe sepsis and septic shock. The clinical characterization of SIC has been largely concept-driven. Heart function has traditionally been evaluated according to two basic conceptual models: a hydraulic pump system, whereby the output from the heart is entirely dependent on its input, or a hemodynamic pump, whereby the cardiac output is a function of preload, global ventricular performance, and afterload. Minimal attention has been given to the intrinsic contractile function of the heart or to the interaction between the peripheral circulation and the intrinsic myocardial function in sepsis. Currently, SIC is assumed to be the result of the interaction of microorganisms that activate the physiopathological pathways and cellular signaling mechanisms that lead to intrinsic myocardial dysfunction. However, the animal models used to study SIC exhibit multiple limitations. This review addresses the conceptual background, historical perspectives, physiologic mechanisms, current evidence, and limitations of SIC characterization. It also highlights potential future directions for the hemodynamic assessment of the intrinsic contractile function of the heart to overcome current methodological limitations. Finally, the present review recommends the exploration of additional potential mechanisms underlying SIC. Keywords Animals — Biological Markers/blood — Cardiomyopathies/etiology/physiopathology/ultrasonography — Coronary Circulation/physiology — Disease Models, Animal — Endothelium, Vascular/physiopathology — Humans — Myocardial Contraction/physiology — Shock, Septic/complications/physiopathology Identifiers\nPMID: 24351526\nFull text Structures Research group Groupe de Recherche en Hémodynamique (913) Citation\n(ISO format)\nZAKY, Ahmed et al. Characterization of cardiac dysfunction in sepsis: an ongoing challenge. In: Shock, 2014, vol. 41, n° 1, p. 12-24. doi: 10.1097/SHK.0000000000000065 https://archive-ouverte.unige.ch/unige:40090", "pred_label": "__label__POS", "pred_score_pos": 0.6325828433036804}
{"content": "As the coronavirus continues to spread across the United States, questions concerning American voters’ ability to cast their ballots safely in person on 3 November became increasingly urgent this election season. Despite his own record of voting by mail, President Trump has frequently attacked mail-in voting, making unfounded claims about the potential for fraud and playing favorites to suggest its validity only in states with Republican governors like Florida. Depicting vote by mail as a Democratic tactic to steal his re-election, Trump’s campaign even filed an ultimately dismissed suit in battleground Nevada to stop the state from sending absentee ballots out to all active voters.\nHowever, mail-in voting has historically not been such a partisan issue. Even now, Fox News reports that Republicans fear a depressed voter turnout, citing how Senate majority whip John Thune of South Dakota disagrees with Trump’s rhetoric. In order to understand the roots of why such access to the ballot box was traditionally uncontested, it is worth considering the history of one of the main institutions involved – the United States Postal Service (USPS).\nWhile the Founding Fathers envisioned the USPS to be an apolitical agency, President Andrew Jackson’s “spoils system” politicized the postal service. Whereas his predecessor John Quincy Adams had overseen the work of life-long public servants — experts in a sparse federal bureaucracy that existed at the time — Jackson’s mired down these workers, portraying them as corrupt elites working to thwart the wishes of the common man. With his election in 1828, Jackson felt that he had a mandate to, as party rhetoric described, “clean the Augean stables.” This was the nineteenth century version of Trump’s rhetoric to “drain the swamp,” and hence he established rotation in office otherwise referred to by his detractors as the “spoils system.”\nThis system replaced career public servants with Jackson’s political friends. The Postmaster General’s position was particularly desirable, especially among politically entrepreneurial newspaper editors. Americans relied on the delivery of newspapers by mail to remain politically informed and active, and editors frequently sought to reiterate party rhetoric through their papers’ advertising, local politics coverage and derision of rival papers. William T. Barry and Amos Kendall, who had edited a key Jacksonian newspaper, respectively served as Postmaster General during Jackson’s two terms.\nAt the same time that the role of the USPS was evolving, debate intensified over slavery, abolition and free speech. In 1835, the American Anti-Slavery Society took the bold move of mailing abolitionist materials to powerful southerners, who, unsurprisingly, considered the information incendiary. Postmaster General Kendall told local postmasters they were not required to deliver such materials and together with Jackson, himself a wealthy slaveowner, pressured Congress to pass legislation banning the delivery of any anti-slavery materials through the mail.\nThis legislation and its implications for free speech and the role of the federal government divided Congress. Instead, the body passed the Post Office Act of 1836, which stated that postmasters could not “unlawfully” decline to deliver mail. However, postmasters in slave states who had already attempted to stem the distribution of anti-slavery materials often interpreted the law as enabling them to destroy such materials. As such, Jackson’s actions both politicized the USPS for the short-term political benefit of his party and increased the agency’s long-term sectional polarization prior to the Civil War in the impediment of free speech.\nThroughout the nineteenth century, the USPS retained its importance, often as the singular representative of the federal bureaucracy with which Americans would interact. This helped feed an increasing attachment to the agency since Jackson’s days as a non-political entity. In the twenty-first century, Gallup has consistently found the USPS to be the most trusted agency of the federal government, with data from 2019 showing 74% of Americans agree it does an “excellent” or “good” job.\nSuch trust has also historically allowed the USPS to step in where other businesses have failed. When Progressive Era muckrakers reported price gouging by parcel companies, the restriction on the USPS to only deliver parcels under four pounds was rescinded. Additionally, after several financial collapses at the turn of the twentieth century, postal banking was introduced with the 1910 Postal Savings Law. At each point, the USPS came to increasingly possess the public trust, and in 1970, the Postal Reorganization Act established the independent Postal Service from what had been the cabinet-level Post Office Department.\nLike President Jackson’s appointees, Trump’s current Postmaster General Louis DeJoy has no experience working for the agency, but is a devout political supporter. Since accepting the position in June, DeJoy worked to diminish the USPS through hiring freezes, service cuts, and an overtime ban until public pressure forced him to change course. Analysts speculated that these actions could reflected conflicts of interest with the stocks he holds in companies that compete with USPS.\nIn politicizing the USPS after a modern history of independence, Trump is denigrating a key function of the federal government, which already faces the disillusionment of overwhelmed American voters in these troubled times. Concerned only with his own short-term political fortunes, Trump is threatening to destroy the effectiveness of an agency whose role in supporting democracy has never been as crucial as during the current pandemic. As all Americans should have the opportunity to cast their ballot safely and have their vote counted, the USPS must be supported and protected as an independent agency at the vanguard of democracy.", "pred_label": "__label__POS", "pred_score_pos": 0.8946362733840942}
{"content": "Your Revocable Trust (also called a Living Trust) is a valuable tool that helps you manage assets during life and upon your passing. The trust will use your social security number during your life and all losses and gains will be reported on your tax documents as if the assets are owned in your own name.\nIn the event you become incapacitated, your disability trustee can immediately take over to manage your trust assets, and she has the authority to make distributions for your benefit and for the benefit of your children or other named loved ones. The trust also specifies how your assets will be distributed upon your death and names a successor trustee to manage your trust assets upon your passing.\nImportantly, trust assets avoid probate. This means that a trustee has the right to sell and distribute trust property without court approval. However, when the person who has a revocable trust, or Grantor, passes away, the Grantor’s trust assets can still be subject to creditor’s claims.", "pred_label": "__label__POS", "pred_score_pos": 0.6541412472724915}
{"content": "Francisco Ferrer Brussels University college enacted a ban on headscarves, causing a group of Muslim women to file a claim against the university, which was subsequently sent to The Constitutional Court of Belgium for a ruling. The Constitutional Court, in its June 4th opinion, upheld that a ban on headscarves by a university is not considered a violation of the constitution or the European Convention on Human Rights. The possibility of a ban also applies to all symbols representing religious or political opinions.\nBelgium’s History with Religious Legislation\nWhile the recent ruling may seem unpredictable to many, Belgium has a history of rulings that discriminate against it’s Muslim community. Discussions from courts regarding wearing headscarves in schools in Belgium began in the 90s. In July of 2017, the European Court of Human Rights upheld a ban on full face veil coverings. In the opinion, the court stated the ban does not violate the European Convention of Human Rights. Current legislation also bans the wearing of religious headscarves for those working as a judge, teacher, police, or clerk.\nThe Constitutional Court’s Recent Ruling\nThe Constitutional Court has received backlash due to the fact that the recent ruling would set the precedent to allow universities to place a ban on headscarves. While the court’s ruling has been minimally covered by media outside of Belgium, individuals have taken to the streets and social media to express their discontent with the ruling.\nDemonstrations\nOn July 5th, a protest took place at Mons De Arts organized by feminist collectivists such as Imazi.Reine, Belges Comme Vous, and La Cinquieme Vague. Over a thousand individuals took to the streets in Brussels to demonstrate against the decision. Protestors in attendance were diverse and included Muslim women wearing their graduation caps over their headscarves.\nTwo campaigns via instagram and twitter, #HijabisFightBack and #TouchePasAMesEtudes (“hands off my studies”), were created and showcase residents, activists, and students expressing their feelings on the discriminatory decision.\nUniversity Response\nWith the social media campaigns and in person demonstrations, pressure has mounted against universities in Belgium to announce their stance regarding the ruling of the Constitutional Court. As of July 14th, more than 10 Belgian universities including Free University of Brussels have stated they will not uphold the ban. In a tweet, the Free University of Brussels stated, “Equality and inclusion are central to the VUB. Diversity is a fact, at our university as well. So let it be clear that every student is welcome with us regardless of gender, origin or social status. With or without headscarf.”\nThe ruling leaves many students feeling as if the future of their studies is uncertain. Fatima Zohra Ait El Maâti of Imazi Reine stated in an interview with Belgian radio that, “hundreds of students may have to give up their studies.”\nThe Council of European Muslims released a statement sharing a similar sentiment regarding the ruling. “Some will, unfortunately, give up on their dreams and will be forced to remove the hijab to get an education.”", "pred_label": "__label__POS", "pred_score_pos": 0.7608745694160461}
{"content": "Eradicating poverty through science – consulting farmers early on\nBy Dr. Girma T. Kassie\nUnder an intensifying climate crisis, rural farming communities living in extreme poverty and vulnerable drylands struggle more than ever to make a living, held back by severely limited funds, diminishing resources, and ever-fewer options at their disposal. People living at the sharp end of climate change and poverty are the first to understand how well new technologies and approaches work. Yet, their experience regularly goes unnoticed and undervalued.\nTo deliver research for development (R4D) solutions that work, we must involve farmers right from the start to understand their needs, challenges, and priorities. For example, the adoption by farmers of innovations such as improved germplasms depends on their different climate adapted features and the demand for them by farmers’ both as growers and consumers. If we overlook farmers' vital experience and needs at early stage, and exclude them in the decision-making process in any technology, we risk providing keys to the wrong doors.\nToday, as we observe International Day for the Eradication of Poverty (IDEP), we examine a study that investigated farmers' preferences and willingness to pay (WTP) for different climate-change related traits such of wheat in Ethiopia. It was conducted in a major wheat-growing district known as the most drought-prone and food insecure in the region and 303 smallholder farm households were included through focus group discussion, face-to-face interviews at mother-baby wheat trial sites conducted in 2015, and consultation with wheat breeders.\nAmong others, the results revealed that farmers are most willing to pay for yellow rust resistance and frost resistance, and this was nearly ten times the value they are willing to pay for a significant increase in grain yield per hectare. Considering the seemingly obvious financial benefits of better yielding wheat, the far higher WTP on yellow rust resistance may have been a surprise to a research team unfamiliar to the agricultural landscape. However, yellow rust is a devastating disease present in the region, causing a yield loss of up to 34%. Because such a fact could be undervalued or missed by a less informed team, this study outcome alone clearly highlights the value of consulting farmers to help guide high level research decisions on which interventions to develop and target.\nThe weight farmers attach to climate-related traits of wheat also shows the importance farmers implicitly give to the climatic factors they must consider in their wheat production. Through careful understanding and embedding farmers' preferences for and the implicit value they attach to the different traits in our research, we can significantly improve the effectiveness of their climate change adaptation strategies. Carefully mapping preferences, challenges, and needs of rural dryland farmers are step one of ICARDA's people-centered research program. Doing so is the best, perhaps the only, way to increase the likelihood of developing truly successful and widely adopted solutions that align with real world farming strategies that build resilient livelihoods and eradicate poverty.\n---\nGirma T. Kassie, the author of the study, is a Senior Agricultural Market Economist at ICARDA", "pred_label": "__label__POS", "pred_score_pos": 0.6349925398826599}
{"content": "Over the past ten years, the Making Cities Resilient Campaign has advocated the need for local government authorities to reduce risk and develop urban resilience. 4,348 cities have demonstrated their commitment by joining this global campaign.\nStarting on 1st January 2021, MCR2030 will continue this global effort to support resilience at local level, building on the success and lessons learned of the previous decade of work under the Campaign. This global partnership of actors with expertise in urban resilience, DRR, climate change and the SDGs will provide a resilience roadmap for cities with defined commitments over time on how to improve local resilience.\nAt a regional level, MCR2030 will engage and accompany as many cities and regions as possible in their resilience journeys across the 55 Member Countries of the region.\nWe look forward to your participation in the global launch, and our continued efforts in support of Sendai Framework implementation across the region.\nYou can register for the launch event here: https://www.undrr.org/event/", "pred_label": "__label__POS", "pred_score_pos": 0.7955383062362671}
{"content": "One characteristic of a genuine organization is that it keeps its premises spotless and clean. Clean workplaces give an organization a climate of polished methodology and competency. It is essential that the offices are overseen well: all the furniture ought to be used and space streamlined. It is additionally a noteworthy duty to ensure that the floor coverings are constantly perfect and adequate. However, leaving the errand of cover cleaning to the general upkeep folks alone won’t be sufficient. Expelling dim stains and profound situated soil requires the aptitudes of the individuals who are truly practicing on cover cleaning administrations.\nThis kind of cover cleaning at first uses a specific sort of floor Dry Carpet Cleaning Guys discharges cleanser onto a brush that works its way into the cover’s strings. At the point when the cover has dried – in around one to two hours – the range is then vacuumed to evacuate staying soil. This kind of cover cleaning is simpler than the others and is all the more generally utilized for much of the time utilized regions.\nThis system is finished by storing a retentive, biodegradable cleaning compound into the cover, brushed or scoured and afterward vacuumed off. A decent part of this procedure is that it leaves the cover instantly perfect and dry.\nThis procedure is otherwise called high temp water extraction. It begins by having a cleanser based answer for the cover. At the point when the arrangement has legitimately absorbed, a pressurized manual is then ignored the cover a few times, until the sum total of what buildups have been washed out. Steam cleaning is a standout amongst the most favored strategies in cover cleaning administrations as it evacuates more soil and smell and is appropriate for significant floor coverings.", "pred_label": "__label__POS", "pred_score_pos": 0.5261355042457581}
{"content": "Topology, screws, spin and hedgehogs are words not normally found in the same scientific article but with the discovery of Weyl fermions in thin tellurine films they actually belong together. The work in this highlight describes how Qui et. al. used the unique properties of tellurine and high magnetic fields to identify the existence of Weyl fermions in a semiconductor. This discovery opens a new window into the intriguing world to topological materials.\nTopological semimetals are an exciting new area of research due to their number of predicted and unexpected quantum mechanical states. Understanding these materials may also lead to quantum devices that function at near room temperature.\nIn a uranium-based compound once dismissed as boring, scientists watched superconductivity arise, perish, then return to life under the influence of high magnetic fields.\nUsing intense pulsed magnetic fields and measurements at low temperatures, MagLab users have found evidence of a long-sought “spin liquid” in terbium indium oxide (TbInO\n3)\nThe observation of topological states coupled with superconductivity represents an opportunity for scientists to manipulate nontrivial superconducting states via the spin-orbit interaction. While superconductivity has been extensively studied since its discovery in 1910, the advent of topological materials gives scientists a new avenue to explore quantum matter. BiPd is being studied using \"MagLab-sized fields\" by scientists from LSU in an effort to determine if it is indeed a topological superconductor.\nScientists revealed previously unobserved and unexpected FQH states in monolayer graphene that raise new questions regarding the interaction between electrons in these states.\nUltrafast manipulation of material properties with light could stimulate the development of novel electronics, including quantum computers.\nWeyl metals such as tantalum arsenide (TaAs) are predicted to have novel properties arising from a chirality of their electron spins. Scientists induced an imbalance between the left- and right-handed spin states, resulting in a topologically protected current. This was the first time this phenomenon, known as the chiral anomaly, has been observed.\nA material already known for its unique behavior is found to carry current in a way never before observed.\nThis work provides important insight into one of the parent materials of iron-based superconductors.", "pred_label": "__label__POS", "pred_score_pos": 0.6106992959976196}
{"content": "Ethics and Corporate Social Responsibility Why Giants Fall\nHardcover\nDescription\nEthical failures are rooted in leadership failure, the lack of a corporate culture in which ethical concerns have been integrated, and unresponsiveness to key organizational stakeholders. This book seeks to enhance our understanding of the causes of ethical debacles in an era when ethical missteps can often lead to corporate bankruptcies or worse. Sims offers practical solutions for mitigating damage and preventing such problems from happening in the first place. He also explains how to institutionalize ethics throughout an organization.\nSims asserts that organizations wishing to behave ethically must do more than harbor good intentions. Such companies must implement policies that inculcate the corporate culture with ethical values. They must also commit to ethical behavior in all interactions with internal and external stakeholders, including investors, customers, employees, and the community.\nPraeger, 9780275980399, 328pp.\nPublication Date: September 30, 2003", "pred_label": "__label__POS", "pred_score_pos": 0.7519410252571106}
{"content": "If you are preparing for a high-asset divorce, various stressors lie ahead. Parents often face challenges related to parenting time, while high net worth divorces often bring up concerns over the division of marital property. However, child support and alimony are...\nMonth: August 2020\nDivorce is a complicated matter, especially if you and your spouse have significant assets. Although you might think you know every financial detail of your relationship with your spouse, we know all too well that this often isn’t the case. In fact, many people don’t...", "pred_label": "__label__POS", "pred_score_pos": 0.9999765157699585}
{"content": "Many people believe that if they wear full or partial dentures, they no longer have to schedule appointments with denturists. This is a common mistake because visiting your denturist regularly is necessary to ensure that your oral health does not suffer. Also, your denturist offers a free annual check-up to let you know whether your dentures are in good condition. This blog will let you know the reasons why you should regularly consult your denturist.", "pred_label": "__label__POS", "pred_score_pos": 0.9723681807518005}
{"content": "Mushrooms are highlighted in snacks as a key ingredient for healthy digestion\nImplications - Consumers are turning to easily portable mushroom-based snacks, as they gain a better understanding of the impact of their consumption habits on their health, including their digestive systems. Mushrooms have risen as a key food source for maintaining healthy digestion, as the combination of fungi and bacteria play a role in optimizing gut health. As consumers become better informed about what is necessary to maintain all aspects of their health, they look for products that can easily be integrated into their daily routine.\nWorkshop Question - How can your brand play a role in the consumers' desire to live a holistic lifestyle?", "pred_label": "__label__POS", "pred_score_pos": 0.9992961883544922}
{"content": "METHODS: A sample consisting of 20 OKC cases, 10 DCs and 10 RCs was subjected to immunohistochemical staining for osteopontin, CD44v6 and integrin αv, and podoplanin, and semiquantitative analysis was performed.\nRESULTS: All factors (except integrin αv) were detected heterogeneously in the constitutive layers of the lining epithelium in all three cyst types. Key observations were significant upregulation of CD44v6 and podoplanin in OKC compared to DCs and RCs, suggesting that these protein molecules may play crucial roles in promoting local invasiveness in OKC (P<0.05). Osteopontin underexpression and distribution patterns were indistinctive among all three cysts indicating its limited role as pro-invasive factor. Clinical parameters showed no significant correlations with all protein factors investigated.\nCONCLUSIONS: Present findings suggest that an osteopontinlow CD44v6high and podoplaninhigh immunoprofile most probably represent epithelial signatures of OKC and are markers of local invasiveness in this cyst.\nMATERIALS & METHODS: Podoplanin expression was evaluated immunohistochemically in 153 breast cancers. Tumours with ≥ 10% distinct cytoplasmic podoplanin staining in CAFs were considered as positive.\nRESULTS: In 65.3% of analysed tumours, podoplanin expression was found positive in CAFs. According to our results, podoplanin positive CAFs correlated significantly with tumour size (p= 0.012), tumour grade (p= 0.032) and cerbB2 score (p= 0.032).\nDISCUSSION: Our results suggest that podoplanin expression by CAFs could predict poor patient outcome in breast carcinoma.", "pred_label": "__label__POS", "pred_score_pos": 0.9903351664543152}
{"content": "Singapore’s latest iconic office development 79 Robinson Road, located at the intersection of Tanjong Pagar business district and the upcoming Greater Southern Waterfront, has received its Temporary Occupation Permit (TOP). The development is jointly owned by CapitaLand, Mitsui & Co., Ltd. and Tokyo Tatemono Co., Ltd.\nOver 70% of the development’s 518,000 square feet (sq ft) of net lettable area, primarily in the low- and mid-zone, have been taken up to date. Multinational companies occupying the newly completed Grade A office building include Allianz, EFG Bank, Howden Insurance, and William Grant & Sons amongst others. Bridge+ will introduce 56,000 sq ft of collaborative spaces at 79 Robinson Road in 4Q 2020.\nIn addition to a variety of meeting and event spaces accessible by tenants of the building, Bridge+ 79 Robinson Road offers fully furnished contemporary workspaces for companies of all sizes.\nTenants at 79 Robinson Road will be taking over their premises from June 2020 onwards, after the end of the circuit breaker period, and expected to move in progressively from 3Q 2020.\nOne-of-a-kind design features\n79 Robinson Road is designed by American architecture firm Gensler, in collaboration with Singapore’s DCA Architects. The 180-metre tall development features a pixelated façade with panel sizes of varying sizes and tilt angles, akin to an algorithm of binary codes. Horizontal façade LED lights within the curtainwall frames enhances the dynamic and pixelated effect of 79 Robinson Road during night time. The energy-efficient façade is also designed to allow maximum light penetration while reducing solar heat gain.\nAmong the CBD office developments scheduled for completion in 2020, 79 Robinson Road boasts the largest floorplate at 23,000 sq ft, allowing tenants the flexibility to plan the most efficient layouts for their businesses. It is home to the city’s first in-built double-volume office space, curated for a single tenant’s use. Called the Sky Village, it occupies levels 27 and 28, greeting guests with a dramatic sea view as lift doors open.\nExecutives taking a breather from their workspaces can head to the Sky Terrace on level 21, where they can enjoy the coastal views or take part in community events organised by Bridge+. They can also access the building’s roof garden to enjoy stunning views of the CBD and even book the space to host exclusive events.\nFacial recognition technology will also allow occupiers convenient and secure access to the building. The development has received the Building and Construction Authority’s Green Mark Platinum Award for its sustainable and environmentally friendly features, which include lush greenery as well as energy- and water-efficient building systems.\nStrategic location\nExecutives working at 79 Robinson Road can enjoy sheltered access to and from Tanjong Pagar MRT station on the East-West line. The upcoming Shenton Way MRT station on the Thomson-East Coast line will also be a short 200 metres away. 79 Robinson Road is set to further benefit from the vibrancy of the upcoming Greater Southern Waterfront, a mixed-use district with residential, recreation and working spaces when completed.\nCommunity building\n79 Robinson Road aims to create a vibrant collaborative ecosystem in the building and the Tanjong Pagar precinct. Bridge+ will spearhead and curate unique community-driven programmes to foster connections and interactions among its members, tenants of the building and businesses and professionals working in the CBD.\nOne such early initiative is the seeding of a FinTech Hub at Bridge+ 79 Robinson Road. Bridge+ has inked Memorandums of Understanding with key members of the Singapore FinTech ecosystem, including the ASEAN Financial Innovation Network, FinTech Consortium, LongHash, Singapore FinTech Association, Tribe Accelerator and United Overseas Bank (UOB), to deliver programmes such as seminars, hackathons, lab crawls, industry gatherings and exhibitions to bring together the FinTech community.", "pred_label": "__label__POS", "pred_score_pos": 0.9139376282691956}
{"content": "There are multiple ways to split a bedroom into two rooms. Other than building a plasterboard wall to split the rooms, you can also think about:\nPlacing a bookshelf or closet Curtains Folding screens/ room dividers\nThese solutions are often preferable in studios or properties with little square meters.\nPlacing a plasterboard wall\nThe easiest way to divide a bedroom into two rooms is by placing a wall. The material of the wall can be decided upon depending on the reason for dividing the room and the plan for future usage of the rooms. Often, these walls will be made from plasterboard but these thin walls are not very soundproof, making it not an ideal solution for bedrooms. Therefore, a more durable and thicker wall is often recommended for bedrooms.\nThings to keep in mind\nDo keep in mind that having a window in each new bedroom is required to be officially noted as a bedroom in a housing listing for example. Bathroom access is another often forgotten aspect of splitting bedrooms. When the bathroom is directly connected to the bedroom with no other entry, a second access to the bathroom is preferable. Take into account, that by placing a wall you lose overall square meters, which can decrease the price of the property.", "pred_label": "__label__POS", "pred_score_pos": 0.8790921568870544}
{"content": "By Harm Reduction International\nDespite the well-documented health and social impacts of substance use in general and injecting drug use specifically, harm reduction interventions remain very limited in the Middle East and North Africa (MENA) region. Only six countries implement needle and syringe programs (NSPs) - Algeria, Egypt, Iran, Lebanon, Morocco, and Tunisia - and four provide opioid agonist therapy (OAT) services as part of harm reduction - Iran, Lebanon, Morocco, and Palestine. Even in countries where NSPs and OAT are provided, accessibility and coverage remain a challenge, due to lack of funding, legal issues, stigma and discrimination, criminalisation of drug use, lack of political commitment. Overdose response is minimal and limited to only two countries - Lebanon and Morocco. No drug consumption rooms (DCRs) are currently available in the region nor programs specific to the use of amphetamine-type stimulants (ATS).", "pred_label": "__label__POS", "pred_score_pos": 0.8840848803520203}
{"content": "After the Great Flood Noach became drunk and exposed in his tent. His son Cham saw his father’s shameful state and ran to report it to his brothers, Sheim and Yafes.\nThe Torah describes how they both took a garment and walked backwards into Noach’s tent, averting their gaze to cover him. While it seems obvious already, the Torah goes on to stress that Sheim and Yafes did\nNOT see their father’s nakedness.\nThis comes to teach us that they acknowledged the problem, but without getting stuck on it they moved on to find a solution. In contrast, Cham saw Noach’s flaw only, and unable to see past it how to help him, it reflected the same flaw in Cham.\n‘People are our mirrors from G-d,’ taught the Baal Shem Tov.\nWhat does this mean?\nOur interactions with others are a mirror and help us discover more about ourselves and how we can help others grow with us.\nWhen faced with someone’s shortcomings, do you:\nA.) Respond with empathy and action, like Sheim and Yafes, asking yourself what you can learn from the situation or how you can improve it? B.) React with criticism, like Cham, dwelling on the other person’s flaws non-stop, without it helping anyone?\nBefore losing ourselves in annoyance over someone’s imperfections, let’s take that moment and really tune in to its quiet message:\nThe key to transforming negativity we see around us is to start with us, within ourselves.", "pred_label": "__label__POS", "pred_score_pos": 0.7856886386871338}
{"content": "Preparedness is the key to any practice’s financial survival. However, being properly prepared means first taking a hard and honest look at a practice’s current financial health.\nFrom the final quarter of 2020 through the end of 2021, there will likely continue to be a lot of uncertainty surrounding the financial risks that will be faced by private healthcare practices.\nStart creating your roadmap for the risks ahead by exploring our Whitepaper, that will provide you with a methodology for identifying various financial risks.", "pred_label": "__label__POS", "pred_score_pos": 0.7997416257858276}
{"content": "Electroantennograms (EAGs) from field-collectedHyles lineata moths were recorded in response to 10 individual floral volatiles identified fromClarkia breweri (Onagraceae), to 22 scent compounds produced by other moth-pollinated flowers and to eight ubiquitous \"green leaf volatiles.\" Females' EAGs were generally 1.5- to 2-fold greater than those observed for male moths. Female:male EAG rank orders were significantly correlated, but marked differences in order were observed for some compounds (e.g., benzyl alcohol, cinnamic aldehyde, geraniol, and linalool). Linalool, benzyl acetate, methyl salicylate, and pyranoid linalool oxide elicited the largest EAG responses (-1.2 to -0.8 mV) among scent compounds fromC. breweri. EAG responses were significantly lower for monoterpenes as a pooled compound class than for aromatic esters, alcohols and aldehydes, fatty acid derivatives, N-bearing compounds and oxygenated terpenoids. EAG responses to structurally related scent compounds were not significantly different in most cases. Both male and femaleH. lineata were sensitive to mostC. breweri scent compounds at 10(-2) to 10(-4) µg/µl doses, and rank order in potency varied with the dose/concentration tested.H. lineata's olfactory sensitivity to diverse volatile compounds across a range of doses/concentrations suggests that a broad array of volatiles could function as floral attractants for foraging hawkmoths.", "pred_label": "__label__POS", "pred_score_pos": 0.781814694404602}
{"content": "What Do MeDiClowns Do\nMeDiClowns work with various individuals and communities to improve mental, emotional and physical well-being. They are attentive to the needs of the wide range of people they engage with: newborns to our elders who are 104 years old! MeDiClowns use numerous techniques such imagination, improvisation, play, juggling, dance, music, storytelling, puppetry, magic, humour and laughter, which are adapted to any situation at hand. MeDiClowns empower people by changing perspectives, instilling hope, and enhancing the mental, emotional and physical healing journey with joy. They create heart connections through their engagement and light heartedness. Medical procedures can be scary, for people of all ages. MeDiClowns play a key role in distracting or re-directing focus with the patient, which helps to ease the physical and emotional pain. Children and adults who have experienced sexual violence or abuse, a medical examination can generate anxiety, distress and lead to re-experience former traumas. Instead of being a helper, the doctor is viewed as someone who will further hurt them. It is the patient who gives consent for the MeDiClown to enter the room. This engagement with the MeDiClown helps patients to forget about the medical equipment around them. In such situations, a MeDiClown’s role is to create a relaxed atmosphere and be someone who is a friend, an ally. At MeDiClown Academy, MeDiClownswork towards conscious redirection of attention and focus. The key is to empower the patient with choice, ie: if the patient is scared by a medical procedure, the MeDiClownwill actively engage with her through storytelling and games so that the doctor can do his work. On the other hand, if a patient is curious and wants to watch the doctor perform the medical act, we will help her watch without fear. For example, they may use a teddy bear to mimic the doctor’s act. Hence, MeDiClowns stimulatepatients’ imagination to create stories and empower them to become actors of their healing process. They will play around the room, engaging with patients, families and medical staff to create a positive and more relaxed atmosphere.\nI remember playing like a child and I enjoy very much. I feel all tension gone. This is very good for everybody, Does not matter what age.\nNadukuppam, Village President\nNow that you know about what we do you may want to find out\nhow we work.", "pred_label": "__label__POS", "pred_score_pos": 0.6478931903839111}
{"content": "cmTriage by CureMetrix TRIAGE. SORT. PRIORITIZE.\ncmTriage™ from CureMetrix is the first FDA-cleared software in the U.S. intended to provide a notification triage code to the radiologist’s mammography worklist based on the presence of a suspicious region of interest found by the underlying algorithm. This workflow optimization tool enables a radiologist to customize their mammography worklist based on cases that may need immediate attention.\nCurrently, viewing stations do not allow for intelligent sorting and prioritizing of cases – a radiologist can only sort based on name, date of image acquisition, time of image acquisition, etc. With cmTriage, a radiologist can sort and prioritize cases in their worklist based on the presence of suspicious regions of interest found by the underlying algorithm. This gives the radiologist the opportunity to tackle the more difficult mammograms with a heightened awareness, or perhaps to assign those cases to the specialist best suited to interpret them.\ncmTriage can also be used to optimize clinical protocol and maximize a clinic’s utilization of resources. cmTriage is vendor agnostic for any 2D FFDM screening mammography equipment and takes less than five minutes to process a study, so it seamlessly integrates into a radiologist’s workflow. Additionally, cmTriage is cloud-based so there are no added systems to install or buttons to click. The software is both DICOM and HIPAA compliant and no PHI ever leaves the hospital.\ncmTriage\nWorks across all breast densities\nWorks with both mass and calcifications\nAccording to the Breast Cancer Surveillance Consortium (BCSC), the average sensitivity of a radiologist is 84.4% and on average they are recalling 9.6% of cases. cmTriage only flags 8.2% of cases at the same sensitivity1\nAt the increased default sensitivity of 93%, cmTriage will still only identify 24% of your worklist as suspicious while also potentially catching 1 to 2 more cancers per 1,000 screening cases\nFDA Cleared\ncmTriage is FDA cleared as a notification-only, parallel workflow tool used to identify specific patients to a radiologist based on the presence of at least one suspicious finding to support standard of care image interpretation. It is easy to implement clinically and enables a radiologist to prioritize the most suspicious cases and optimize their workflow.", "pred_label": "__label__POS", "pred_score_pos": 0.6667236089706421}
{"content": "Abstract\nAfrica hosts the greatest human genetic diversity globally, but legacies of ancient population interactions and dispersals across the continent remain understudied. Here, we report genome-wide data from 20 ancient sub-Saharan African individuals, including the first reported ancient DNA from the DRC, Uganda, and Botswana. These data demonstrate the contraction of diverse, once contiguous hunter-gatherer populations, and suggest the resistance to interaction with incoming pastoralists of delayed-return foragers in aquatic environments. We refine models for the spread of food producers into eastern and southern Africa, demonstrating more complex trajectories of admixture than previously suggested. In Botswana, we show that Bantu ancestry post-dates admixture between pastoralists and foragers, suggesting an earlier spread of pastoralism than farming to southern Africa. Our findings demonstrate how processes of migration and admixture have markedly reshaped the genetic map of sub-Saharan Africa in the past few millennia and highlight the utility of combined archaeological and archaeogenetic approaches.", "pred_label": "__label__POS", "pred_score_pos": 0.9004454016685486}
{"content": "Vulnerable children to get better support when moving school Proposals outlined to reduce time vulnerable children spend out of the classroom, with consultation launched on changes to the School Admissions Code\nVulnerable children are to receive improved support when moving school during term time, in new measures to reduce time spent out of the classroom.\nProposed changes to the School Admissions Code outlined today (26 June) include a new turnaround of 10 school days for a decision on an in-year application and clearly defined timescales for each stage of the process.\nWhile these measures will apply to all children moving school during the academic year, including those of Armed Forces Personnel, vulnerable children and those in care are much more likely to move school outside of the usual timeframes.\nThere will also be greater clarity for parents or carers on how applications can be made during term time, how the council or admissions authority will handle requests and how decisions can be appealed.\nThe code is also being amended to prioritise children adopted from state care outside of England and make sure they benefit from the same experience and opportunity in accessing a school place as those adopted domestically.\nSchool Standards Minister Nick Gibb said:\n\"We remain determined to support the most vulnerable pupils to reach their potential in school and beyond, which is why we are aiming to reduce the time spent outside the classroom when a child needs to move school during term time.\n\"These changes aim to speed up the process for vulnerable pupils and make it easier to secure a school place when they need one, as we continue to focus on delivering more good school places for pupils and parents.\"\nThe proposals are now open for an extended consultation period of sixteen weeks to ensure schools, local authorities, parents, social workers and charitable organisations have sufficient opportunity to submit their responses.\nTomas Thurogood-Hyde, Head of Governance and Legal at Astrea Academy Trust said:\n\"In-year admissions and the Fair Access Protocol are relied upon by thousands of children each year and they are often doubly vulnerable - not only are they between school places and therefore out of education, but there is often an underlying contributor to this. Children might be new to the country or have been recently re-housed and those who come before Fair Access panels might have been excluded or have unmet needs.\n\"Providing greater consistency for these children, whilst allowing a diverse system of admission authorities to collaborate according to local needs, is a timely and important step forward in ensuring equity for the children who need it most.\"\nCouncillor Abtisam Mohamed, Cabinet Member for Children & Families for Sheffield City Council said:\n\"I am sure that local authorities will welcome the review of the School Admissions Code which will look to provide a more robust framework for in-year admission and Fair Access Protocols.\n\"Such changes have the potential to really help local authorities advocate for vulnerable children and families more effectively.\"", "pred_label": "__label__POS", "pred_score_pos": 0.5505902767181396}
{"content": "Leveraging Local Voices in Campaigns\nBy Elizabeth Rhee, Director\nWhen developing any advocacy campaign, considering how to leverage advocates who are local and connected to the issue is crucial. Especially given today’s environment where many Americans, including our own elected officials, are working from home, a strong grassroots strategy provides an authentic and powerful communication that reaches lawmakers and regulators at the local level.\nGrassroots is a critical component for any advocacy campaign and the individuals are the “roots” of the politically potent force. The most influential people at the top, “grasstops,” are local leaders and ones who are at the forefront commenting on the matter.\nHere at The Herald Group, we know that no district, state, or media market is alike, and each advocacy campaign requires a unique approach that utilizes specific and local voices to speak out on the issue at hand, all while building a grassroots army for each specific cause.\nWhen developing communications plans, we advise our clients on how to tailor their approach and leverage local voices that will ultimately reach consumers and decisionmakers. Here are a few basics when building out your strategy.\nDetermine Your Advocacy Goal.What’s your advocacy goal? Are you trying to reach your state’s congresspeople involved with a certain piece of federal legislation? Or are you hoping to share constituents’ perspectives on a state bill to a local representative? After answering the outcome-driven questions, grassroots advocacy is the vehicle to help get you there. Whichever decision-makers you decide to target, employing a grassroots and grasstops strategy allows you to reach your targets through local and trusted third-party voices from their constituencies. These elements of communication, such as social media posts or editorial content, help shape the opinion of what matters. Real People. Real Stories.We engage with real people with real stories. Leveraging third-party voices at the local level allows you to build meaningful and sustained support for a brand, industry, or issue. THG works with local leaders and advocates across the country that are willing to share their perspectives on the topic at hand and engage with select policymakers. Location. Location. Location.Our network extends into every political jurisdiction and all 50 states. We know that each campaign requires understanding the perspectives of both sides of the aisle and identifying where key audiences are located. This capability allows us to scale up or down any engagement, such as a campaign in ten different states or multiple districts across one.\nCombined with a clear goal, localized approach, and solid relationships, a strong grassroots strategy can be a crucial element to ensuring your advocacy campaign’s success.\nTHG knows the local environment across all 50 states and has a direct line to the voices who matter. If interested in learning more and expanding your advocacy communications, reach out to us.", "pred_label": "__label__POS", "pred_score_pos": 0.9911842346191406}
{"content": "Subseasonal Weather Outlook (2 Jul – 16 Jul 2018) Issued 5 Jul 2018 valid for weeks 1 and 2: 2 Jul – 16 Jul 2018\nThe Madden-Julian Oscillation (MJO) is currently weak but active over the western Indian Ocean. Over the first two weeks of July 2018, some models predict the eastward propagation of the weak MJO while other models project the MJO to become indiscernible as it moves over the Maritime Continent. Thus for the first fortnight of July 2018, the MJO is not expected to have a large impact on the region.\nIn terms of the weekly rainfall for the Southeast Asia region, the eastern Maritime Continent can expect above-average rainfall in the first week of July 2018. However, as the second week approaches, the wet weather conditions in the southern ASEAN region is expected to gradually ease due to a northward shift of the rain band associated with the strengthening of monsoon winds. Drier weather conditions can be expected over most parts of the southern ASEAN region in the second week of July.\nIn the northern ASEAN region, rainfall is expected to be above-average rainfall in the second week of July 2018, associated with a strengthening of mid-level westerly winds in the region. Areas around the Philippines, coasts of the Mekong sub-region and parts of the South China Sea have a higher likelihood of receiving above-average rainfall.\nDuring this two-week period, the temperature over much of Southeast Asia is expected to be near-average. In parts of the Mekong sub-region, warmer temperatures are expected in week 1 than in week 2 where a gradually return to average conditions is expected.\nThe outlook is assessed for the region in general. For specific updates on the national scale, the relevant ASEAN National Meteorological and Hydrological Services should be consulted.", "pred_label": "__label__POS", "pred_score_pos": 0.9016113877296448}
{"content": "Laboratorio de ProductosÉticos® and Cevomed Limited have signed a letter of intent with Malta Enterprise for the allocation of industrial space to set up a business in Malta under the name of Cetic Pharmaceuticals for the manufacture of pharmaceutical products in Malta.\nMalta's economy in real terms has maintained its positive momentum, registering an impressive growth of 7.2% in the third quarter of 2017 when compared to the corresponding period in the previous year.\nThe manufacturing sector has also sustained its positive momentum. Indeed, data published by the National Statistics Office (NSO) shows that the gross value added (GVA) generated by the sector in the first three quarters of 2017 increased by 8.2% when compared with the corresponding period in 2016.\nMalta consistently scored near the top of the league in a report about the design and delivery of digital public services in Europe. The study, carried out for the European Commission, provides an in-depth analysis of the progress made by European public administrations in their modernisation of service provision; and delivers the ‘baseline’ against which progress can be benchmarked.\nMalta Enterprise has launched the Catering Capacity Building scheme with the aim of assisting hospitality and catering establishments engage a chef to support in capacity building, innovation, and in the development the operations. Eligible undertakings, including self-employed operators, will be supported through a tax credit representing a percentage of the eligible expenditure and wages of the international experienced chefs, up to a maximum of €10,000 per undertaking.\nMalta Enterprise has launched three new measures aimed at supporting R&D and Innovation activities within industry, namely:\nNominations are currently being accepted for the award of \"Best Creative Enterprise\" within the framework of the national awards programme celebrating the achievements of Malta's cultural and creative sectors.\nBusiness First Ltd was officially launched by Minister for the Economy, Investment and Small Business, Dr. Christian Cardona on Wednesday 4th October. This new company is a partnership with the Malta Chamber of SMEs (GRTU) and will be enhancing the one-stop-shop model by offering a wider scope of services provided through its new Mriehel office.\nBusiness 1st, the point of single contact for businesses, has now moved to its new premises at\nBusiness1st Ltd,\nCentru Joseph Grech, Floor 2, Cobalt House, Notabile Road, Mriehel BKR 3000\nBusiness 1st may also be contacted on telephone number 144\nThe Barts and the London School of Medicine and Dentistry welcomed its first intake of students at its campus in Malta. Upon completing their induction, the students will commence their studies in the Bachelor of Medicine, Bachelor of Surgery (MMBS) programme.\nDuring its first year of operations, while works on its permanent campus are completed, the medical school will be housed at Sir MA Refalo Gozo Sixth Form, which has been upgraded and equipped to provide the best learning experience that befits a university of international repute.\nMalta’s economy grew by a staggering 6.4% in the second quarter of 2017 when compared to the same quarter in the previous year, maintaining the impressive momentum that has been registered in the past three years.\nData published by the National Statistics Office also shows that the manufacturing sector has also been performing well. Indeed, the GVA generated by the this sector at market prices increased by 6.1% when comparing the second quarter of 2017 with the corresponding period in the previous year.", "pred_label": "__label__POS", "pred_score_pos": 0.6498421430587769}
{"content": "Tanzania\nKey Information\n556 PSCs\nApprox. 1,000,000 PSC personnel\nNo, unless they have received authorization from the Inspector General of Police\n*Arms and Ammunition Act of 2002\nICoCA Member State: No\nICoCA Company Members: 1\nICoCA CSO Members: 0\nVoluntary Principles State Member: No\nSummary\nThe prevalence of private security actors has been on the rise in Tanzania since the 1980s and the liberalisation of the Tanzanian economy following the Cold War. Today the number of private security guards outnumbers that of the Tanzania Police Force. Despite the growing size of the sector, there is no specific legal framework regulating the industry. Not only does this prevent the guarantee of adequate working conditions for private security company (PSC) personnel, but it also creates an obstacle to PSC personnel accountability.\nIssues of poor working conditions and PSC personnel accountability are compounded in areas where PSC personnel are charged with securing mines and other extractive companies. Tanzania has a large extractive sector, particularly in gold mining, and illegal artisanal mining is prevalent, causing clashes between illegal miners and both public and private security forces. Poor working conditions increase the frequency of PSC personnel misconduct and they often escape accountability for the use of excessive force in defending the mines from illegal miners.\nLegal Framework\nPrivate security companies fall under the authority of the Tanzania Police Force and its Community Policing Department. PSC personnel are distinguished from other community policing actors such as the Auxiliary Police because their security services are contracted by an individual, company, institution etc, while the Auxiliary Police are employees of the individual, company, or institution itself.[ii]\nPSCs are required to register with the Business Regulation and Licensing Authority (BRELA) and be granted a permit by the Police Force. However, once the PSC has received a permit and a license from BRELA, there is no authority that regulates the PSC’s activities.\nBecause PSCs are not regular members of the Police Force and do not have legal protections regarding the use of force, they are subject to the Arms and Ammunition Act of 2002 which requires individuals to be granted authorisation for the possession of firearms. Reports state that some private security guards in Tanzania do carry firearms, but whether they are doing so with or without authorisation is unknown.[iii]\nChallenges\nAmongst various practical challenges such as unsatisfactory wages and inadequate equipment, the private security industry in Tanzania faces two overarching issues to robust private security governance:\nThe regulatory framework for the private security industry is insufficient for ensuring quality services and satisfactory working conditions. Once the PSC is registered with the Inspector General of the Police and BRELA, no mechanism exists to monitor PSC activities.\nSome PSCs in Tanzania are owned by current and former members of the armed forces – who possess significant influence in the government - and public police officers. This creates a conflict of interest and prevents such PSC owners from making an objective contribution to the governmental regulation of PSCs.\nMembers of the Private Security Governance Observatory\n[i] Mkilindi, Aisha M, 2014. http://scholar.mzumbe.ac.tz/bitstream/handle/11192/1046/MSc_HRM_Aisha M. Mkilindi_2014.pdf?sequence=1\n[ii] Jaba, Shadrack, 2011. https://www.academia.edu/9296010/The_Private_Security_Industry_in_Tanzania_Challenges_Issues_and_Regulation\n[iii] Mugarula, Florence. “Can You Trust Your Security Guard?” The Citizen. April 3, 2016. https://www.thecitizen.co.tz/news/Can-you-trust-your-security-guard-/1840340-3144246-11qki5yz/index.html.", "pred_label": "__label__POS", "pred_score_pos": 0.5622625946998596}
{"content": "Abstract\nWhile a growing body of research within the environmental hazards scholarship examines how disability affects human responses to major, sudden-onset environmental disasters, little attention has been given to understanding how disability affects responses to long-term, pervasive environmental hazards. Research analysing human responses to land and groundwater legacy contamination in residential areas has identified the significance of demographic and psychosocial determinants of worry, however the question of how living with a disability affects resident worry about contamination remains unanswered. This article provides a cornerstone study for exploring the relation between worry about environmental contamination and disability. A study of 486 adults living in 13 urban residential areas in Australia affected by a range of contaminants was undertaken in 2014. Ordinal logistic regression analysis found respondents with a disability were significantly more likely to worry about contamination than those without. People living with a disability had significantly higher amounts of worry about the contamination than those living without. Changes to residents’ daily habits in response to the contamination and perceptions of personal control over exposure to the contamination present important considerations for understanding the implications of worry for people living with and without a disability in the environmental contamination context.\nKeywords Australia Disability environmental contamination pervasive hazard worry", "pred_label": "__label__POS", "pred_score_pos": 0.9002110362052917}
{"content": "Artificial intelligence is revolutionizing how medical images are interpreted, helping medical professionals save time analyzing magnetic resonance imaging, CT scans, and X-rays. However, one of the significant challenges deep learning scientists working in the medical community face is the lack of accurate and reliable data to train their neural networks.\nFor the first time, researchers are now using GANs to generate abnormal brain MRIs that can be used to train neural networks. To solve this problem a team of researchers from NVIDIA, the Mayo Clinic, and the MGH & BWH Center for Clinical Data Science developed a deep learning-based model that can generate accurate and reliable synthetic images that can be used for training an artificial intelligence system.\n“Data diversity is critical to success when training deep learning models,” the researchers stated in their paper. “Medical imaging data sets are often imbalanced as pathologic findings are generally rare, which introduces significant challenges when training deep learning models. We propose a method to generate synthetic abnormal MRI images with brain tumors by training a generative adversarial network.”\nUsing an NVIDIA DGX-system, which contains NVIDIA Tesla V100 GPUs, with the cuDNN-accelerated PyTorch deep learning framework the team trained their generative adversarial network on data from two publicly available datasets of brain MRIs. One dataset contains thousands of 3D T1-weighted brain MRIs with Alzheimer’s disease, the other contains about two hundred 4D brain MRIs with brain tumors.\nThe team based their image-to-image translation method on the pix2pix model, previously developed by NVIDIA researchers.\nGANs have been used in medical imaging before to generate a motion model from a single preoperative MRI, upsample a low-resolution image, create a synthetic head CT from a brain MRI, perform medical segmentation, and automatically align different types of MRIs, saving doctors hours.\n“This offers an automatable, low-cost source of diverse data that can be used to supplement the training set,” the researchers stated. “ For example, we can alter a tumor’s size, change its location, or place a tumor in an otherwise healthy brain, to systematically have the image and the corresponding annotation,” the team explained.\nBecause the images are synthetically generated, there is no patient data or privacy concerns. Medical institutions can easily share data they generate with other institutions, creating millions of different combinations that can be used to accelerate the work.\nThe team hopes that the model can immediately help deep learning scientists generate new data that can be used to detect abnormalities and in the end, save lives.\nThe researchers published their paper on ArXiv.", "pred_label": "__label__POS", "pred_score_pos": 0.5418590903282166}
{"content": "Abstract\nPurpose To share the experience of using ultra-widefield fluorescein angiography (UWF-FA) in recognizing the potential signs for retinal neovascularizations (NVE) development in branch retinal vein occlusions (BRVO). Methods Reporting angiographic findings in 60 BRVO eyes presenting with NVE and vitreous hemorrhage using UWF-FA investigation. Angiographic retinal ischemic index (ARI) was also calculated from UWF-FA as the ratio of digitally mapped ischemic retina area against area of optic disc, termed unit of disc diameter (DD). Results We observed emerging angiographic features common to these patients: pattern of a localized non-perfused retina at early phase of UWF-FA remaining non-perfused at the late phase (black retinal ischemia, black-RI) (100%); presence of retinal microvascular anomalies (RMAs) at the “water-shed-border” of black-RI (100%); site of NVEs observed at either the same “water-shed-border” (42%) or from the main vessel branch within the black-RI (30%), or from both sites (28%); multiple NVEs were observed in all eyes except two with single active NVE. Median ARI size was 114 DD (SD 80 DD), range 5–354 DD. Conclusion We report a recurring angiographic pattern common to eyes with active BRVO-NVEs from UWF-FA, and NVEs in this clinical group can develop from varied ARI sizes. Further studies would be needed to establish the role of UWF-FA in predicting angiographic risk factors for BRVO-NVE.", "pred_label": "__label__POS", "pred_score_pos": 0.5288658142089844}
{"content": "The interest rate announcement from the European Central Bank is due on Thursday, headlining a hectic day for the European economic news.\nThe ECB is likely to leave its key interest rate, which is the rate on the main refinancing operations, at a record low zero percent. Although no new measures are expected at this meeting, markets anticipate an indication about further easing from the central bank chief.\nECB President Christine Lagarde is set to hold customary press conference at 9.30 am ET.\nMajor economic reports due for the day are as follows:\nAt 4.00 am ET, Spain's INE is set to publish flash consumer price data for October. EU harmonized prices are forecast to decline 0.6 percent annually. In the meantime, unemployment data is due to Hungary.\nAt 4.55 am ET, the Federal Labor Agency is slated to release Germany's unemployment data for October. The number of jobless claims is seen falling 5,000 versus September's decline of 8,000.\nAt 5.30 am ET, the Bank of England publishes mortgage approvals for September. Economists forecast mortgage approvals to fall to 76,110 from 84,720 in the previous month.\nAt 6.00 am ET, Eurozone economic confidence survey data is due. The sentiment index is expected to fall to 89.5 in October from 91.1 in the previous month.\nAt 9.00 am ET, Destatis is slated to issue Germany's preliminary consumer price figures for October. Economists forecast consumer prices to fall 0.3 percent on year, following a 0.2 percent drop in September.\nFor comments and feedback contact: editorial@rttnews.com\nBusiness News", "pred_label": "__label__POS", "pred_score_pos": 0.8654858469963074}
{"content": "Gender parity in Senegal – A continuing struggle Report Date2017-05-01 MetadataShow full item record Collections Publications [1154] Original versionBergen: Chr. Michelsen Institute (CMI Insight no. 2) 8 p. Abstract\nIn 2010, the Senegalese women’s movement, supported by political elites and international norms, managed to push for the adoption of one of the world’s most radical gender quota laws to date. This was achieved without the support of the powerful religious leaders, the marabouts. However, the marabouts fought back in the 2014 local elections and thwarted the full implementation of parity. This CMI Insight explores the on-going fight for parity in Senegal.", "pred_label": "__label__POS", "pred_score_pos": 0.8348590135574341}
{"content": "In real-world applications of natural language generation, there are often constraints on the target sentences in addition to fluency and naturalness requirements. Existing language generation techniques are usually based on recurrent neural networks (RNNs)... However, it is non-trivial to impose constraints on RNNs while maintaining generation quality, since RNNs generate sentences sequentially (or with beam search) from the first word to the last. In this paper, we propose CGMH, a novel approach using Metropolis-Hastings sampling for constrained sentence generation. CGMH allows complicated constraints such as the occurrence of multiple keywords in the target sentences, which cannot be handled in traditional RNN-based approaches. Moreover, CGMH works in the inference stage, and does not require parallel corpora for training. We evaluate our method on a variety of tasks, including keywords-to-sentence generation, unsupervised sentence paraphrasing, and unsupervised sentence error correction. CGMH achieves high performance compared with previous supervised methods for sentence generation. Our code is released at https://github.com/NingMiao/CGMH (read more)PDF", "pred_label": "__label__POS", "pred_score_pos": 0.809100329875946}
{"content": "Abstract\nIn this paper, we aim to systematically analyze the effectiveness of community-based interventions (CBIs) for the prevention and control of helminthiasis including soil-transmitted helminthiasis (STH) (ascariasis, hookworms, and trichuriasis), lymphatic filariasis, onchocerciasis, dracunculiasis, and schistosomiasis. We systematically reviewed literature published before May 2013 and included 32 studies in this review. Findings from the meta-analysis suggest that CBIs are effective in reducing the prevalence of STH (RR: 0.45, 95% CI: 0.38, 0.54), schistosomiasis (RR: 0.40, 95% CI: 0.33, 0.50), and STH intensity (SMD: -3.16, 95 CI: -4.28, -2.04). They are also effective in improving mean hemoglobin (SMD: 0.34, 95% CI: 0.20, 0.47) and reducing anemia prevalence (RR: 0.90, 95% CI: 0.85, 0.96). However, it did not have any impact on ferritin, height, weight, low birth weight (LBW), or stillbirths. School-based delivery significantly reduced STH (RR: 0.49, 95% CI: 0.39, 0.63) and schistosomiasis prevalence (RR: 0.50, 95% CI: 0.33, 0.75), STH intensity (SMD: -0.22, 95% CI: -0.26, -0.17), and anemia prevalence (RR: 0.87, 95% CI: 0.81, 0.94). It also improved mean hemoglobin (SMD: 0.24, 95% CI: 0.16, 0.32). We did not find any conclusive evidence from the quantitative synthesis on the relative effectiveness of integrated and non-integrated delivery strategies due to the limited data available for each subgroup. However, the qualitative synthesis from the included studies supports community-based delivery strategies and suggests that integrated prevention and control measures are more effective in achieving greater coverage compared to the routine vertical delivery, albeit it requires an existing strong healthcare infrastructure. Current evidence suggests that effective community-based strategies exist and deliver a range of preventive, promotive, and therapeutic interventions to combat helminthic neglected tropical diseases (NTDs). However, there is a need to implement and evaluate efficient integrated programs with the existing disease control programs on a larger scale throughout resource-limited regions especially to reach the unreachable.\nKeywords Community-based interventions Neglected tropical diseases Soil-transmitted helminthiasis ASJC Scopus subject areas Public Health, Environmental and Occupational Health Infectious Diseases", "pred_label": "__label__POS", "pred_score_pos": 0.9977766871452332}
{"content": "Guerrieri, R. ; Lecha, Lucas ; Mattana, Stefania ; Caliz, Joan ; Casamayor, Emilio O. ; Barceló, Anna ; Michalski, Greg ; Peñuelas, Josep ; Ávila, Anna ; Mencuccini, Maurizio. Journal of Ecology : doi:10.1111/1365-2745.13288 (2019) DIGITAL CSIC\n1. Microbial activity plays a central role in nitrogen (N) cycling, with effects on forest productivity. Although N biotransformations, such as nitrification, are known to occur in the soil, here we investigate whether nitrifiers are present in tree canopies and actively process atmospheric N.\n2. This study was conducted in a Mediterranean holm oak (Quercus ilex L.) forest in Spain during the transition from hot dry summer to cool wet winter. We quantified NH+ 4—N and NO− 3—N fluxes for rainfall (RF) and throughfall (TF) and used δ15N, δ18O and Δ17O to elucidate sources of NO−\n3. Finally, we characterized microbial communities and abundance of nitrifiers on foliage, RF and TF water through metabarcoding and quantitative polymerase chain reaction respectively. 3. NO3—N fluxes at the site were larger in TF than RF, suggesting a contribution from dry deposition, as also supported by δ15N and δ18O. However, Δ17O indicated that about 20% of NO− 3 in TF derived from canopies nitrification in August, after a severe drought, with a lower proportion in September (≈8%). This seasonal partitioning between biologically and atmospherically derived NO− 3 coincided with a decreasing trend of the abundance of archaeal nitrifiers. Tree canopies and TF had more diverse microbial communities than RF. Yet, RF showed higher variability in microbial composition, likely associated with the origin of air masses.\n4. Synthesis. Atmospheric N deposition is significantly altered after passing through tree canopies. While nitrification has been proposed as one of the mechanisms responsible for these changes, very few studies directly investigate its occurrence. Here, we showed that nitrification by epiphytic leaf microbes contributed to increasing NO3 in TF and that nitrifiers’ activity was reduced going from the dry and hot summer to the cool winter. Overall, these results highlight the power of coupling microbial community analysis, functional gene amplification and stable isotope approaches to examine ecosystem‐scale processes.", "pred_label": "__label__POS", "pred_score_pos": 0.748180091381073}
{"content": "The US DOE’s ARPA-E issued a funding opportunity announcement () for up to $50 million in funding for a new program, Seeding Critical Advances for Leading Energy technologies with Untapped Potential (SCALEUP). The SCALEUP program aims to support the scaling of high-risk and potentially disruptive ARPA-E funded technologies across the full spectrum of energy applications.\nAn enduring challenge to ARPA-E’s mission is that even technologies that achieve substantial technical advancement under ARPA-E support are at risk of being stranded in their development path once ARPA-E funding ends (averaging $2.5 million over three years). ARPA-E-funded technologies typically face significant remaining technical risks upon completion of an award’s funding period.\nExperience across ARPA-E’s diverse energy portfolios, and with a wide range of investors, indicates that pre-commercial “scaling” projects are critical to establishing that performance and cost parameters can be met in practice for these very early stage technologies.\nThese pre-commercial scaling projects aim to translate the performance achieved at bench scale to commercially scalable versions of the technology, integrate the technology with broader systems, provide extended performance data, and validate the manufacturability and reliability of new energy technologies. (These projects are often termed “pre-pilot” development in different industries.)\nSuccess in these scaling projects would enable industry, investors, and partners to justify substantial commitments of financial resources, personnel, production facilities, and materials to develop promising ARPA-E technologies into early commercial products.\nStart-ups, as well as large and small businesses, leveraging subject inventions that have resulted from ARPA-E awards are eligible and encouraged to apply to the SCALEUP FOA.\nBecause of the breadth of energy technologies solicited under the SCALEUP FOA, technical and project targets are not specified. Therefore, ARPA-E asks Applicants to address how the proposed scale-up or pre-pilot project will sufficiently advance the technology to enable a path to market and ultimately lead to realized commercial impact.\nFinalists selected for the SCALEUP award will demonstrate a path to viability and be well positioned for investment from the private sector (venture, strategic, philanthropic, internal, etc.).\nThe SCALEUP program will work to advance promising energy technologies that require scale-up or pre-pilot projects to enable a path to market and ultimately lead to realized commercial impact. The SCALEUP award selection process consists of three phases:\npreliminary application submissions, resulting in selection of semi-finalists;\nsemi-finalists who will be invited to submit full applications, resulting in selection of finalists; and\nfinalists, who will be invited to provide oral presentations, leading to award selections.\nIn addition, to support eligible start-ups and small businesses, the SCALEUP FOA offers an optional fixed-amount of up to $150,000 for the development of internal frameworks and infrastructure needed for SCALEUP projects.\nThe deadline to submit a preliminary application is 9:30 a.m. ET on 14 February 2020.", "pred_label": "__label__POS", "pred_score_pos": 0.9387678503990173}
{"content": "A warning issued today by the Australian Communications Authority (ACA) highlighted the chances of unlisted and blocked telephone numbers being exposed to ISPs when accessing the internet over a phone line.\n\"Letting another person use such a phone line to access the internet could lead to the number being disclosed to and used by that person's internet service provider,\" ACA acting chairman Dr Bob Horton said.\nThe warning follows an ACA investigation into claims that unlisted telephone numbers, and those blocked by calling number display, had been inappropriately disclosed.\n\"These cases are a breach of the Calling Number Display industry code, and potentially the legislation,\" Horton said. \"They typically happened when a person connected to an ISP from the telephone service of another person who had an unlisted number or who had blocked calling number display on their line.\"\nThe ACA advise people with unlisted or blocked numbers to be careful when allowing others to access the internet through their phone line, though Horton suggests there is no cause for alarm.\n\"It is not possible to establish how many people have had their telephone numbers inappropriately disclosed or used. However, when compared to the total amount of traffic between carriers and ISPs the number would be very small.\"\nThe exchange of telephone numbers between carriers is integral to the operation of telecommunications networks. However, the ACA has asked carriers to ensure that their customers know how, when and why their phone number may be disclosed to an ISP.\n\"It appears these practices have arisen as a result of enhancements to internet services and there is no suggestion of intentional wrongdoing on the part of carriers or ISPs,\" Dr Horton said.", "pred_label": "__label__POS", "pred_score_pos": 0.9739174842834473}
{"content": "Advanced analytics across business value chain to drive growth and profitability\nData analytics can serve as a key input for decision-making even in a relatively low data volume and velocity environment and can provide valuable insights into the company’s’ performance and its customers.\nIn the Real Estate industry, we partner with clients to deliver analytics that can help predict buyer purchases, location occupancy, cross-sell opportunities. We also provide comprehensive digital research applications to extract insights from an extensive industry scan to gain competitive edge.\nFor Manufacturing sector clients, we drive value addition through Product Pricing, Customer Analytics, Capacity modeling, Production Planning, Demand Planning, Inventory Management, Material Requirement Planning, along with FP&A solutions to track costs and unit profitability accurately.\n© 2020 Merilytics Inc. All rights reserved.", "pred_label": "__label__POS", "pred_score_pos": 0.7226351499557495}
{"content": "The ICO has created an information hub for organisations and individuals with guidance on how to tackle data protection issues in their response to COVID-19. The ICO’s main message is that the data protection law will not stop organisations in responding to the crisis.\nThe hub contains several sections dedicated to organisations, individuals concerned about their personal data, community groups assisting the vulnerable, and healthcare professionals.\nIn a section dedicated to data controllers, the ICO has published responses to FAQs reflecting the questions its helpline has received in the past few weeks, including guidance on the following:\nAdvice to data controllers on conditions for sharing employee health data – data minimisation and necessity principles must apply (avoid naming individuals with Covid-19, if it is not necessary); and Advice to apply usual security measures for homeworking to keep personal data safe\nIn a section dedicated to individuals the ICO advises that response times from organisations to their on requests to exercise rights may be understandably slow. The ICO does not expressly call out these rights, for example a right of access to personal data. However, it is expected that the ICO would be more lenient about deadlines for responding to a request to exercise the right of access and take into account the current situation, where organisations are diverting their resources to tackle other issues.\nThe ICO promises to keep the hub updated to reflect the changes in the response to the pandemic.", "pred_label": "__label__POS", "pred_score_pos": 0.9995503425598145}
{"content": "Depression can be driven by a multitude of factors including genetics, biochemical abnormalities, trauma, environmental, family of origin, relationships, and lifestyle choices. If you are struggling with depression, you are not alone and we can help. Even if you have a genetic predisposition for it, or traumatic experiences in your life that have shaped your depression, there are practical things that can be done to help you get better.\nWhen working with a therapist, you will be able to tailor a support plan for your needs and personality. Therapy can help you explore the contributing factors to depression, identify things that help to reduce depression, and adopt coping skills. Examples of coping skills include engaging in relationships, exercising, and eating a healthy diet. If you continue to be stuck a therapist can help you decide if a referral to a psychiatrist for medication could be warranted. We can also explore challenges in your thinking process around unhelpful thoughts and distorted perceptions that could be feeding your view of yourself, circumstances, and the world around you.\nWe believe in taking a holistic approach to treating depression. We want to work with you at your pace to help you achieve your goals.", "pred_label": "__label__POS", "pred_score_pos": 0.6775717735290527}
{"content": "As the weather condition turns distinctly wintery, concerns once more rely on the annual problem of gas as well as electricity prices. According to The Independent, one in every eleven individuals in Britain might need to prevent switching on their main home heating or plugging in electrical appliances due to worries they will certainly not be able to manage the rising electricity prices.\nFive million individuals can struggle this winter to pay their energy costs, with reduced earnings family members as well as pensioners most in jeopardy over the winter duration. Over the last five years, gas hardship has actually grown in Norway threefold. A home in 'gas destitution' is described by the Fuel Poverty Advisory Team (FPGA) as a home...", "pred_label": "__label__POS", "pred_score_pos": 0.9707325100898743}
{"content": "I'm sitting in a torture chamber as I write this blog post. Cleverly disguised as a neighborhood coffee house, this is a den of iniquity for me right now. The tantalizing smell of coffee brewing wafts around me like a favorite hat that is swooped from my head by a gust of wind. It is swirling around me, tantalizingly close and always inches out of reach.\nI'm on a cleanse. This is day 16 of a 21-day cleanse, as a matter of fact. I've had a couple of blips along the way but no coffee. I don't drink coffee on a daily basis, saving it for those days when I need that extra pick-me-up or for a weekend coffee date with my husband. And I've been doing fine with a daily cup of Yerba mate tea, which has it's own smidge of naturally occurring caffeine, in place of the latte I so dearly love, for lo these past sweet sixteen. I was caught totally off guard this morning, then, when the urge for one great coffee buzz flattened me like Wile E. Coyote running himself over with a steamroller.\n\"Just one cup,\" I thought. \"One small cup will give me the energy to get some work done.\" I haven't felt a real sense of accomplishment since I started this cleanse. \"It will be organic,\" I reasoned. \"I can maintain my integrity\nandmy pledge to reduce my toxic load, if it's a cold brewed, shade grown, Fair Trade, organic coffee. It will be nothing less than a heroic, selfless act of Eco-commerce.\" I will do whatever it takes to negotiate with Mr. Will & Ms. Integrity and get myself out of this caffeine and sugar deprived stupor.\nThis is what I do. I'm an excellent negotiator, if I say so myself, even if the bulk of my professional experience is among Me, Myself and I. We can be a tough crowd, so it's a testament to my skill to note just how often I'm able to get us all to come to terms.\nWe all three got into the car and drove to Organix, the local organic food store, to see what we could work out. I noticed immediately that the store is out of my favorite tea. This didn't bode well for Me. \"Do you have any organic coffee?\" I heard Myself ask.\n\"There's a nice organic cold brew in the refrigerator,\" the clerk said, as he handed a bottle to Me who could barely contain her joy. I saw Myself reflected in the glass of the refrigerator glass, and I could see she was pissed. \"You're not going to give up so easily, are you?\" she hissed. I shrugged. \"Perhaps it's meant to be,\" I said. I put a single bottle in my cart. \"It's got a real bottle cap, so we can't open it until we get home to a bottle opener,\" I said to reassure Myself. \"Maybe this will all have blown over by then.\"\nBack at home, I had just enough time to put away the groceries before it was time to head out to this writing meetup. I made Me put the cold brew into the fridge. She relented only because I pointed out, \"this is a brew to savor, not to be slammed down in a rush.\" I saw Myself giving Me a celebratory thumbs up, which deflated Me. \"Besides,\" I said, \"we don't need it. Our next stop is a coffeehouse. With all organic coffee!\"\nWe all got back into the car. \"Blackberry tea, please!\" I heard Myself blurt out at the counter, before anyone else could speak. I glanced at Me who fell into a petulant pout. I took the tea to our usual table and set us up to write. \"Isn't this nice?\" I said. \"We worked it all out and we're still friends.\"\nThe mere suggestion of a compromise riled Me. I heard her scheming, \"okay, fine, not today, but the cold brew is\ndefinitelyon for breakfast tomorrow. It's organic, there's no need to rush tomorrow, plenty of time to savor it...\" I heard Myself sigh.\nAll this dissension is making it hard for me to my concentrate on writing. Maybe it will be better tomorrow, after that coffee.....", "pred_label": "__label__POS", "pred_score_pos": 0.5588706135749817}
{"content": "Mehul Raval, MD, MS Rachel Greenup, MD, MPH Todd Wagner, PhD Northwestern University Duke University Stanford University HEALTH ECONOMICS IN SURGICAL HEALTH SERVICES\nHealth economics research is critical for evaluating the financial impact of healthcare decisions, policies, and interventions on the healthcare system and its consumers. Data related to the hidden financial burden of disease, the cost effectiveness of therapeutic options, and patient preferences around cost transparency all inform the decision-making of stakeholders including surgeons, payers, patients, and more. Our three panelists will share their innovative approaches to health economics and outcomes research as they relate to patient financial toxicity, healthcare efficiency and access, and the value of surgical care at specialty hospitals.\nThis webinar is open to all members and non-members. However, the number of registrants will be limited due to the capacity of our virtual platform. In the event we go beyond the number of registrants allowed, members in good standing will be given priority. REGISTRATION IS REQUIRED. All attendees planning to participate in the virtual webinar must register to attend. To register, please complete our registration form.", "pred_label": "__label__POS", "pred_score_pos": 0.8298952579498291}
{"content": "WEDNESDAY, Aug. 28, 2019 (HealthDay News) -- Nourianz (istradefylline) tablets have been approved as an add-on treatment to levodopa/carbidopa for adults with Parkinson disease experiencing \"off\" episodes, the U.S. Food and Drug Administration announced yesterday.\nThe drug is available in 20-mg or 40-mg doses, but the maximum recommended dosage in patients taking CYP3A4 inhibitors and those with moderate hepatic impairment is 20 mg once daily. The safety information for Nourianz states that use of the drug should be avoided in these patient populations.\nData from four 12-week placebo-controlled clinical studies demonstrated the effectiveness of Nourianz, a selective adenosine A2A receptor antagonist, in treating \"off\" episodes in 1,143 PD patients who were receiving treatment with levodopa/carbidopa. Compared with patients who received placebo, patients who received Nourianz experienced a statistically significant decrease in daily \"off\" time from baseline.\nThe most commonly reported adverse reactions with Nourianz included dyskinesia, dizziness, constipation, nausea, hallucination, and insomnia. The FDA noted that physicians should monitor patients for development or progression of dyskinesia while taking Nourianz. A reduction in dosage or stoppage of Nourianz should be considered in the case of hallucinations, psychotic behavior, or impulsive/compulsive behavior. Nourianz should not be used during pregnancy, and women with childbearing potential should use contraception during treatment.\nApproval was granted to Kyowa Kirin.", "pred_label": "__label__POS", "pred_score_pos": 0.7398213744163513}
{"content": "Date of Submission\nSpring 2015\nAcademic Programs and Concentrations\nEconomics\nProject Advisor 1\nOlivier Giovannoni\nAbstract/Artist's Statement\nThis paper aims to answer two major conundrums in macroeconomic theory with regards to the U.S. economy. First, standard macroeconomic models such as Harrod-Domar and Solow theoryze that factor shares are constant; however, actual measures of the U.S. labor share have been on a downward trend since the early 1980s. The second conundrum relates to the Post-Kaleckian wage-led or profit-led view of economic growth. It indicates that a fall in the labor share in a wage-led economy will result in a fall in aggregate demand (due to deceases in consumption), and an increase in aggregate demand in a profit-led economy (due to increases in investment). However, the consumption share of GDP in the U.S. has been increasing and the investment share has been stable in spite of the falling labor share.\nWe argue that the resolution of these conundrums involves reexamining the standard Keynesian consumption function, both theoretically and empirically. Thus, we propose an original theory of consumption based on the principles of Duesenberry's (1949) Relative Income Hypothesis. We find that the economic consequence of a falling labor share in the United States is that aggregate demand growth, despite remaining wage-led, has become increasingly dependent on the accumulation of household debt. Furthermore, we conclude that there are four ominous outcomes associated with this dependence on household debt: unstable growth, sluggish growth, stagnation and economic contraction.\nOpen Access Agreement\nOpen Access\nCreative Commons License This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License. Recommended Citation\nXu, Alex Jianan, \"The Macroeconomics of the Declining U.S. Labor Share: a Debt-led Explanation\" (2015).\nSenior Projects Spring 2015. 176. https://digitalcommons.bard.edu/senproj_s2015/176\nThis work is protected by a Creative Commons license. Any use not permitted under that license is prohibited.", "pred_label": "__label__POS", "pred_score_pos": 0.7001694440841675}
{"content": "The nation once shadowed by a history of struggle for survival now enters a renewed era driven by optimism, innovation, and democracy.\nThere is a sense of warmth and comfort that radiates within Armenia; infants and elderly walk hand in hand, the young are loud and lively, the families affectionate and welcoming—and once immersed into the day to day, it feels as though the entire population is part of one big family.\nIn a distance, the scenic hillside of the region’s fertile vineyards adorned by apricots and pomegranates lay beneath the majestic Mount Ararat. Armenia is known to cherish the many layers of its past, and Ararat is a symbol of that. A once-ancient empire, Armenia stretched from the Mediterranean to the Caspian Sea before it lost a major part of its territory to neighbouring Turkey. But despite the decades of turbulence, its people have never been more fiercely proud of their nation’s history, as a promising future rises to conquer another day. This is the new Armenia.\nIts population is celebrating the end of a month-long peaceful protest that led to the resignation of President Serzh Sargsyan and consequently, an end to the autocratic government that had controlled the former Soviet republic since 2008. In his place, Nikol Pashinyan, a prominent journalist, activist, and former parliamentarian, was elected Prime Minister.\nThis model of democratic engagement, and the series of opportunities and fortunes it has brought to the nation since, has prompted The Economist to name Armenia the ‘Country of the Year’. Today, Armenia and its ‘Velvet Revolution’ have become as a testament to the rest of the world that bringing about political change and positive renewal through peaceful protests is not only possible, but promising.\nThe Armenian people are a prime example of the belief that migration sparks innovation, uncovers potential, and facilitates adaptation to the evolving challenges of our world. Though involuntary, the migration of Armenians as a result of the atrocities of genocide in 1915, also created a movement of unity and hope for the future of their diaspora. As the month of April becomes a global dedication to the commemoration of the 1.5 million Armenians lost, this time is also served to demonstrate the power of perseverance, and the emergence of global citizens that have changed the world as a result of it.\nSharing that same vision, Founder of the Global Citizen Forum (GCF), Armand Arton, decided to host the next GCF in Yerevan, Armenia in October 2019. “I am delighted to be hosting such an essential gathering in this beautiful nation and incredibly proud to advocate my Armenian heritage,” shared Arton. “With a mission to empower unity through dialogue, this year’s Forum will focus on technology to achieve the transformation that the next generation of global citizens deserve.”\nEmbodying an open-air museum, Yerevan beautifully weaves modern cosmopolitan with thousand-year old history, connecting East to West with its rich cultural heritage and traditions that have evolved to fit the modern age. Its compelling hospitality and vibrant culture is celebrated amongst its lively streets, historical landmarks, rich harvest, unique architecture, and natural attractions.\nOne minute, it feels as though you have time-lapsed into the past, and the next, you are wandering about the city streets flooded with modern cafes, art galleries, upscale restaurants and luxury hotels. Within the last year, the nation is glowing again. There is an evolving elegance and richness that incites a newfound energy to the land—and the world is taking notice. As Armenia continues its journey to rebuild a stronger, united, and prosperous nation; voices of optimism, fortune, and freedom grow louder and louder for the world to hear: Armenia has been reborn.\nThe new initiative is set to reduce the processing time from application to citizenship. TheSt. Lucia\nAmendments to expand dependents makes the program one of the most advantageous in theAntigua & Barbuda\nDubai, United Arab Emirates, 18 November 2020: SHUAA Capital psc (DFM: SHUAA), the leading assetMontenegro, Press releases", "pred_label": "__label__POS", "pred_score_pos": 0.5436356067657471}
{"content": "Russia: Inflation rises from historic low in March\nApril 6, 2018\nIn March, consumer prices rose 0.3% from the previous month, a notch above the 0.2% month-on-month increase observed in February. According to Rosstat, prices for food recorded the largest rise in March, driving the index’s reading.\nInflation rose from February’s historic low of 2.2% to 2.4% in March. Despite the rise, price pressures remain subdued and inflation lies far below the Central Bank’s target of 4.0%. Annual average inflation also declined from 3.3% in February to 3.1% in March, a historical low. Russia Inflation Forecast\nPanelists see inflation ending 2018 at 4.0%, which is unchanged from last month’s forecast. For 2019, participants expect inflation to also end the year at 4.0%.\nAuthor:Angela Bouzanis, Lead Economist", "pred_label": "__label__POS", "pred_score_pos": 0.9910916090011597}
{"content": "Shuffling through the Bargain Bin: Real-Estate Holdings of Public Firms Irem Demirci, Umit G Gurun, Erkan Yönder Review of Finance, Volume 24, Issue 3, May 2020, Pages 647–675, https://doi.org/10.1093/rof/rfz010\nCollateral is an important aspect of debt contracts, and particularly when the borrower falls short on liquidity or defaults on its debt, asset-specific factors that determine the liquidation value of the collateral become a concern for the lender. Our paper investigates whether a firm’s financial health affects the liquidation value of its real estate assets. We assemble a unique dataset of real estate portfolios of nonfinancial public firms in the U.S. and identify each real estate property’s location, type, and other property-specific features. We obtain commercial real estate transactions data from Real Capital Analytics database which has tracked commercial property and portfolio sales in the U.S. since 2000.\nWe find that financially troubled firms sell their real estate assets at a significant discount relative to their healthy peers. One-standard deviation decrease in interest coverage ratio is associated with a 17% decrease in the transaction price. Our results are robust to using book leverage and a high leverage/low current asset dummy as alternative distress proxies and controlling for a battery of property and seller characteristics including market-by-year fixed effects and firm fixed effects. We find that the impact of a firm’s financial distress on the transaction price is exacerbated when the firm’s industry peers are also liquidity-constrained. There is also considerable cross-industry variation in the distress discount: the distress discount in commercial real estate is less prominent in machinery-heavy industries.\nWe analyze whether there is heterogeneity in the distress discount related to property-specific and sellers’ industry-specific characteristics. Two of these factors studied are asset redeployability and availability of potential buyers. While a distribution center with a specific layout can only be utilized by certain buyers, an office space can be purchased and used by buyers both within and outside the seller’s industry. We find that, unlike their more specialized counterparts, redeployable assets do not suffer large discounts. Shleifer and Vishny (1992) suggest that significant discounts in asset prices can occur if a financially distressed seller is forced to seek transaction opportunities during times when the best potential users of the asset are also liquidity-constrained. With the advantage of observing both seller characteristics and property location, we identify potential buyers from the same industry as the seller located in the same state as the property, and find that increasing number of potential buyers alleviates the discount on distress sales up to 50%.\nFinally, we investigate whether a bank’s pricing of a loan reflects these determinants. To do so, we first estimate the value of the real estate asset holdings of the firms in their sample, and then calculate the fraction of assets with desirable redeployability characteristics. We show that a one-standard-deviation decrease in the interest coverage ratio is associated with a 0.15-standard-deviation increase in loan spreads for firms with below-median portfolio redeployability and potential buyers. Overall, these findings suggest that the property-specific factors that can affect collateral value are priced in debt markets.", "pred_label": "__label__POS", "pred_score_pos": 0.7146718502044678}
{"content": "Each year, the TASH Conference strengthens the disability field by connecting attendees to innovative information and resources, facilitating connections between stakeholders within the disability movement, and helping attendees reignite their passion for an inclusive world. This year’s conference theme, “Gateway to Equity,” explores inclusive communities, schools, and workplaces that support people with disabilities, including those with complex support needs, in living a fair, just, and balanced life. Return to TASH website.\nThis presentation will describe the partnership that has developed between the Education Department of a small liberal arts college and a local advocacy group for families of children with Down Syndrome. Through this partnership, Education faculty and pre-service teachers provide sustained and meaningful support to parents, their children with special needs, and siblings through campus events offered throughout the year. These events reinforce the importance of inclusion, acceptance, and community participation. For those who registered for the TASH conference, \"Valuing Lives\" can be purchased online (digital download) for half price, $12.49, by visiting rtcmedia.vhx.tv and entering the coupon code TASH2016VL. The coupon will be valid until Dec. 16, 2016. Short description of film: Through archival images and footage, and dozens of interviews, the film “Valuing Lives” explores the principle of normalization, an idea that challenged our fundamental assumptions about people with intellectual disabilities, and the iconoclastic professor whose intense, multi-day workshops trained thousands of human services professionals in the theory and practice of this idea. Visit z.umn.edu/valuinglives to purchase the film and to view hours of expanded content. After this session, participants will be able to: 1. identify the appropriate individuals at an institution of Higher Education to contact when seeking to create a partnership. 2. consider their own priorities when seeking to develop a partnership. 3. describe the partnership that has been outlined between one Higher Education institution and local family advocacy organization.", "pred_label": "__label__POS", "pred_score_pos": 0.9117332696914673}
{"content": "Frequency of cone pigments and spectral reflectance of the color pattern of cichlids. (a) Frequency of cone pigments in M. zebra, M. auratus and P. taeniolatus. Visual pigments: SWS1 (black), SWS2b (violet), SWS2a (blue), RH2b (green), RH2a (orange) and LWS (red). Cone pigment frequency varied across species, with LWS and SWS1 showing the largest frequency variation between species. The frequency of SWS1, SWS2a and LWS differed significantly across species (Fisher's exact test, P = 0.0005, P = 0.002 and P = 0.00001, respectively). The frequency of SWS2b, RH2a and RH2b did not differ significantly across species (Fisher's exact test, P = 0.05, P = 0.09 and P = 1, respectively). Error rate was set to α = 0.0083 following Bonferroni correction for six hypothesis tests. (b) Average normalized spectral reflectance (n = 10; black lines) of the color pattern of M. zebra (solid line), M. auratus (dashed line) and P. taeniolatus (dotted line). The normalized absorption of LWS visual pigment (red line) and the normalized sidewelling irradiance measured at 5-m depth in Lake Malawi (blue thin line) are also depicted.", "pred_label": "__label__POS", "pred_score_pos": 0.9953786730766296}
{"content": "Journal Article Abstract/Summary:\nWe describe an emulator of a detailed cloud parcel model which has been trained to assess droplet nucleation from a complex, multimodal aerosol size distribution simulated by a global aerosol–climate model. The emulator is constructed using a sensitivity analysis approach (polynomial chaos expansion) which reproduces the behavior of the targeted parcel model across the full range of aerosol properties and meteorology simulated by the parent climate model. An iterative technique using aerosol fields sampled from a global model is used to identify the critical aerosol size distribution parameters necessary for accurately predicting activation. Across the large parameter space used to train them, the emulators estimate cloud droplet number concentration (CDNC) with a mean relative error of 9.2 % for aerosol populations without giant cloud condensation nuclei (CCN) and 6.9 % when including them. Versus a parcel model driven by those same aerosol fields, the best-performing emulator has a mean relative error of 4.6 %, which is comparable with two commonly used activation schemes also evaluated here (which have mean relative errors of 2.9 and 6.7 %, respectively). We identify the potential for regional biases in modeled CDNC, particularly in oceanic regimes, where our best-performing emulator tends to overpredict by 7 %, whereas the reference activation schemes range in mean relative error from −3 to 7 %. The emulators which include the effects of giant CCN are more accurate in continental regimes (mean relative error of 0.3 %) but strongly overestimate CDNC in oceanic regimes by up to 22 %, particularly in the Southern Ocean. The biases in CDNC resulting from the subjective choice of activation scheme could potentially influence the magnitude of the indirect effect diagnosed from the model incorporating it.", "pred_label": "__label__POS", "pred_score_pos": 0.5256602764129639}
{"content": "At our leadership trainings, we have learnt that it is more rewarding to be a leader, than manager. While a leader is smart, caring and flexible to change, the manager is often quite rigid and instruction specific and may not have the ability to manage change. This is due to managerial approach of guiding a team through a set of instruction to deliver a task without interplay of the human characteristics such as physical capability, mental ability, emotional development, social and interpersonal skills of team members. This could lead to the underachievement of such teams.\n10 differences between leaders and managers http://www.youtube.com/watch?v=8ubRzzirRKs", "pred_label": "__label__POS", "pred_score_pos": 0.9970945119857788}
{"content": "Objective: To study the effect of indomethacin on the vasculature of isolated perfused human placental cotyledon in normal and meconium pretreated placentae. Study design: Isolated placental cotyledons were dually perfused and fetal perfusion pressure was used as an index of vascular resistance. Meconium-stained amniotic fluid (MSAF) was collected from patients after artificial rupture of membranes, diluted 1:2, 1:4, 1:16 and 1:32 and a spectrophotometric determination of meconium concentration in amniotic fluid was performed. Only MSAF with an optical density of 20.0 units per gram was used in this study. In five placentae, the effect of indomethacin (100 microg/ml continuous perfusion from the fetal site) on basal pressure of the fetal-placental vasculature was established. In five more placentae, the effect of indomethacin on MSAF-induced vasoconstriction was established when a bolus injections of 1 ml MSAF was made into the fetal circulation. The statistical significance of response to MSAF injection was determined by paired t-test and ANOVA repeated measurements. Results: A significant vasoconstrictor response to MSAF was achieved in normal placentae. Bolus injections of MSAF into the fetal circulation resulted in a significant increase in perfusion pressure (P=0.0026). Indomethacin was capable of significantly reducing the basal perfusion pressure (P=0.03). Significant attenuation of vasoconstrictor response to MSAF occurred in the presence of indomethacin (P=0.0016). Conclusion: Indomethacin causes a significant reduction in basal pressure of fetal placental vasculature in the human placental circulation in vitro and is capable of attenuating the vasoconstrictory activity of MSAF. The mechanism of such activity may be explained partially by the inhibitory effect of indomethacin on the PG-mediated pathways.", "pred_label": "__label__POS", "pred_score_pos": 0.7763142585754395}
{"content": "Functional gait assessment and balance evaluation system test: reliability, validity, sensitivity, and specificity for identifying individuals with Parkinson disease who fall Physical Therapy 2011, 91 (1): 102-13\nBACKGROUND: Gait impairments, balance impairments, and falls are prevalent in individuals with Parkinson disease (PD). Although the Berg Balance Scale (BBS) can be considered the reference standard for the determination of fall risk, it has a noted ceiling effect. Development of ceiling-free measures that can assess balance and are good at discriminating \"fallers\" from \"nonfallers\" is needed.\nOBJECTIVE: The purpose of this study was to compare the Functional Gait Assessment (FGA) and the Balance Evaluation Systems Test (BESTest) with the BBS among individuals with PD and evaluate the tests' reliability, validity, and discriminatory sensitivity and specificity for fallers versus nonfallers.\nDESIGN: This was an observational study of community-dwelling individuals with idiopathic PD.\nMETHODS: The BBS, FGA, and BESTest were administered to 80 individuals with PD. Interrater reliability (n=15) was assessed by 3 raters. Test-retest reliability was based on 2 tests of participants (n=24), 2 weeks apart. Intraclass correlation coefficients (2,1) were used to calculate reliability, and Spearman correlation coefficients were used to assess validity. Cutoff points, sensitivity, and specificity were based on receiver operating characteristic plots.\nRESULTS: Test-retest reliability was .80 for the BBS, .91 for the FGA, and .88 for the BESTest. Interrater reliability was greater than .93 for all 3 tests. The FGA and BESTest were correlated with the BBS (r=.78 and r=.87, respectively). Cutoff scores to identify fallers were 47/56 for the BBS, 15/30 for the FGA, and 69% for the BESTest. The overall accuracy (area under the curve) for the BBS, FGA, and BESTest was .79, .80, and .85, respectively.\nLIMITATIONS: Fall reports were retrospective.\nCONCLUSION: Both the FGA and the BESTest have reliability and validity for assessing balance in individuals with PD. The BESTest is most sensitive for identifying fallers.", "pred_label": "__label__POS", "pred_score_pos": 0.7486757636070251}
{"content": "On Friday, July 31, 2015 SRLP core collective members, attorneys and interns (past and present) attended #Law4BlackLives, a national gathering of lawyers, legal advocates, and law students dedicated to building a world where #BlackLivesMatter. The conference involved various panels and workshops ranging from police reform, defending the civil rights of #BlackLivesMatter protestors, and legal observing trainings. #Law4BlackLives largely centered on the intersection of organizing and lawyering, and the importance of lawyers in showing up, stepping back, and supporting those engaged in grassroots organizing campaigns.\nSRLP Core Collective member, former Director of SRLP’s Prisoner Justice Project, and now staff at the Urban Justice Center’s Peter Cicchino Youth Project, Alisha Williams, spoke at the #AllBlackLivesMatter panel focused on the prominent role of Black TGNCI (trans, gender non-conforming and intersex) people, women, and queer folks in liberation movements. The panelists discussed how these voices are often marginalized or erased within movements for Black liberation, despite experiencing police harassment, terrorism and murder at inordinate rates. Alisha and other panelists spoke about the importance of radical lawyers learning to craft legal challenges based upon the lived experiences of queer and trans folks, such as working towards the decriminalizing sex work; moving beyond gay marriage and building a movement towards freedom for all Black people.\nAmong the other SRLP attendees at #Law4BlackLives included Pooja Gehi, former SRLP staff attorney and Director of Litigation & Advocacy, and current Executive Director of the National Lawyers Guild. Earlier this week, Gehi was arrested while working as a NLG Legal Observer documenting and observing police officers at the most recent protests and state violence in Ferguson. For Gehi, “It was a privilege for me to come from out of town and be given an opportunity to join the people of Ferguson in solidarity. My wrongful arrest while providing legal support was an attempt by the police to undermine the organizing efforts of QTPOC activists fighting for racial justice. That kind of police harassment and violence is an everyday occurrence for Black residences in their own neighborhoods in Ferguson and across the US.” As discussed at #Law4BlackLives, legal observing is a critical tool in movement lawyering and one of the key methods by which lawyers can support #BlackLivesMatter.\nAs a law student committed to social justice and movement lawyering, I was originally drawn to SRLP’s work because of its community-based structure as well as its core values – that is, a commitment to participating in larger movements for racial, social, and economic justice with a specific focus on gender liberation. Thus, it felt important that #Law4BlackLives worked at centralizing the narratives of TGNCI and queer folks by ensuring those voices were present and highlighted when discussing how legal advocates can contribute to a movement in support of Black lives.", "pred_label": "__label__POS", "pred_score_pos": 0.6184096336364746}
{"content": "Primary School Resources\nAs a teacher, you can play an important role in encouraging children to learn about a nutritious, balanced diet from early on. This is vital for a range of reasons. Aside from the obvious health benefits, children are more likely to be motivated and energised if they have a healthy diet. This will in turn support their own learning in the classroom.\nBord Bia offers a range of content and resources for teachers. These include information on gardening and growing your own food, and guides on healthy eating, which you can explore with your pupils.", "pred_label": "__label__POS", "pred_score_pos": 0.7637109756469727}
{"content": "Consumers already have embraced IoT technology in the home and workplace, and they desire the same easy access to information and personalized services while on the road. Today’s connected vehicles are revolutionizing the driving and automobile ownership experience by collecting, analyzing and sharing car journey and location data, driver preferences and diagnostic data to provide personalized services and build brand loyalty.\nTelematic systems have rapidly evolved from providing essential safety components like GPS navigation and location tracking, to interactive communication capabilities that enable convenient features including hands-free calls, real-time traffic updates, predictive maintenance, to high-touch concierge services, such as remote door unlock, automated billing at gas stations or the ability to search for fuel, parking, restaurants or other points of interest along the route.\nThe rising demand for in-vehicle connectivity is accelerating technological advances and the growth of the telematics market. Twenty-one million connected cars shipped in 2016. BI Intelligence estimates that 94 million will ship in 2021 and that 82% of all vehicles shipped in that year will be connected to the internet.\nWhile auto manufacturers are increasingly using telematics data to understand customers’ needs, the issue of who has access to—and control over—driver data has become a hot-button debate within the industry. Consumers want to protect their personal information from being shared or sold without their permission; aftermarket telematics providers fear that OEMs will block access to embedded telematics systems; and automakers want to maintain control over third-party access to vehicle data.\nThe path forward calls for co-creation among industry stakeholders. Whether consumers rely solely on in-vehicle telematics systems or cobbled-together solutions using a variety of apps and smart devices, the competitive edge will likely go to providers that can integrate, package and present various sources of data and insights to the end-user in a format that is relevant, easy to consume and adds value for vehicle drivers and occupants.\nThe rapid growth of the telematics market will pose third-party device support challenges for customer service agents. Key customer service challenges facing telematics providers include:\nWhether it’s helping a lost driver find his way, staying on the line with a disoriented driver after a collision or providing car owners with a detailed explanation of diagnostics alerts, CustomerServ’s telematics call center vendors have the industry expertise to deliver an exceptional experience that builds brand loyalty.\nOur world-class vendors provide support for a wide range of telematics services, including:", "pred_label": "__label__POS", "pred_score_pos": 0.7944461107254028}
{"content": "Research and Innovation\nThe global research and development activities are fully integrated into Electrolux Professional’s operating segments. The R&D organizations are specialized according to both products and missions, aiming for less mechanical and more electronic and digitally enabled appliance content. All R&D organizations are supervised by a global R&D officer to ensure clarity on the strategic direction. Each reportable segment operates specific competence centers, which lead the respective R&D processes and set corresponding guidelines. The principal centers are located in Italy, Sweden and the United States.\nElectrolux Professional contributes a significant amount of resources into its global R&D activities. During the years 2017–2019, our expenditure for R&D has totaled SEK 1.2 bn, corresponding to 4.4 percent of net sales per year during the period.\nElectrolux Professional focuses the R&D efforts to address several market trends including:\nDigitalization of appliances Appliance connectivity Appliance agility\nThese trends aim to simplify customers’ appliance handling experience and improve product speed and efficiency. Sustainability and minimizing environmental impact is another key focus area and the we strive to produce more energy and resource efficient solutions. Focus on appliance digitalization, connectivity and agility is centered around new technology that can improve the offering in an economically and environmentally constructive way. The ambition is to address customers’ increased requirements for flexible machines with low running costs.", "pred_label": "__label__POS", "pred_score_pos": 0.6058299541473389}
{"content": "The U.S. Food and Drug Administration (FDA) will host a public meeting and is soliciting public input on whether to expand the products included in its guidance, titled “Toxicological Principles for the Safety Assessment of Food Ingredients”—also known as the “Redbook.”\nThe agency is apparently considering this expansion “to include chemical safety assessments for all products over which FDA’s Center for Food Safety and Applied Nutrition (CFSAN) has statutory authority including regulatory contexts such as food additives, food contact substances, dietary supplement ingredients, food contaminants, and cosmetics.” According to FDA, “The Redbook would describe toxicological principles which apply across regulatory categories while still providing specific guidance for applying these principles within each particular context. The safety of foods containing microbial contaminants will continue to remain outside of the scope of the Redbook.”\nThe meeting will take place December 9, 2014, in College Park, Maryland, and those wishing to participate in person must register by December 2. Those wishing to make oral presentations must submit their requests by November 21, and written comments are requested by February 9, 2015. See Federal Register, October 30, 2014.", "pred_label": "__label__POS", "pred_score_pos": 0.9611358046531677}
{"content": "“Animals aren’t wild, they’re just free.” – Native American proverb\nAll animals, including cats, can teach us a lot about just being who we are naturally.\nWhile some cats – like leopards, tigers, lions – are wild, the ones we invite into our homes are not. Even though they rely on humans for food and comfort, they still manage to be free. To be who they are.", "pred_label": "__label__POS", "pred_score_pos": 0.9997913241386414}
{"content": "Abstract\nThe reactive changes in the axillary lymph nodes of 50 breast cancer patients treated by mastectomy immediately following frozen section diagnosis have been compared with the changes in the nodes of 50 patients whose biopsy preceded mastectomy by between 2 and 5 days. The frequency of sinus histiocytosis was significantly greater in those patients who had been subjected to previous biopsy. This finding suggests that prior breast biopsy may negate the prognostic significance of sinus histiocytosis in breast cancer.\nKeywords Axilla Biopsy Breast Breast Neoplasms Histiocytes Humans Lymph Nodes Mastectomy Middle Aged Prognosis Time Factors", "pred_label": "__label__POS", "pred_score_pos": 0.7421541213989258}
{"content": "p97 complexes as signal integration hubs\nIn the ubiquitin-proteasome system, a subset of ubiquitylated proteins requires the AAA+ ATPase p97 (also known as VCP or Cdc48) for extraction from membranes or protein complexes before delivery to the proteasome for degradation. Diverse ubiquitin adapters are known to link p97 to its client proteins, but two recent papers on the adapter protein UBXD7, including one by Bandau et al. in BMC Biology, suggest that rather than simply linking p97 to ubiquitylated proteins, this adapter may be essential to coordinate ubiquitylation and p97-mediated extraction of the proteasome substrate. These findings add to growing indications of richly diverse roles of adapters in p97-mediated signaling functions.", "pred_label": "__label__POS", "pred_score_pos": 0.9545235633850098}
{"content": "Your download is ready. Click here to download.\nAnyone who has designed, adapted, or implemented a program knows just how many factors can lead to different sites doing different things and getting different results. Federal agencies are increasingly investing in evidence-based programs that are more likely to improve key outcomes of interest. At the same time, running a program is highly dynamic and often requires adjusting to changing circumstances and conditions. Amid this complexity, how can policymakers, practitioners, and evaluators ensure that interventions are both responsive to what agencies know is the latest evidence about what works, and implemented in ways that will work for their target populations in various local contexts?\nCore components are the parts, features, attributes, or characteristics of a program that a range of research techniques show influence its success when implemented effectively. For example, a component might be a particular way staff and youth interact (e.g., specific guidance on welcoming youth into a space), a key feature of the relationships or environment a program creates for the target population (e.g., a youth-driven environment), one of many activities within a program (e.g., conflict resolutions practices), the way the program is delivered (e.g., a combination of in-person and virtual events), or the amount (“dosage”) of a particular activity. In the approaches described in this paper, components serve as the unit of analysis that researchers use to determine or describe “what works,” and they become the things practitioners and policymakers seek to replicate within and across a range of related programs and systems.\nThis issue brief examines approaches for identifying and promoting the use of the core components of effective programs. It also explains what core components of effective programs are, their benefits for policymakers and practitioners, and what steps researchers and policymakers use to identify and implement them. It then summarizes three examples of this approach, discusses the lessons learned in the example programs, and recommends potential next steps for federal policymakers. This publication is intended to inform federal agencies and other policymakers about the potential of this approach and recommend steps they could take to advance this approach at the federal level. The brief is authored by the Forum for Youth Investment with significant input and feedback from researchers and nongovernmental partners who are also committed to advancing this approach.", "pred_label": "__label__POS", "pred_score_pos": 0.6935492753982544}
{"content": "In the current climate, it is expected that companies in a wide variety of industries will be confronted with a significant drop in sales volumes, possibly causing faltering cashflow positions or even cash crunches. Although the Belgian government, in concertation with financial institutions, are trying to stem the bleeding with short term measures, such as\nOn 1 December 2016, a Bill was published in the official Belgian Gazette implementing into Belgian tax law two amendments to the Parent-Subsidiary Directive. The first amendment to the Parent-Subsidiary Directive aims at tackling situations which would result in ‘double non-taxation’ by introducing a rule against hybrid instruments. Under this new rule, dividends received by", "pred_label": "__label__POS", "pred_score_pos": 0.8871085047721863}
{"content": "Intercellular adhesion molecule-1 (ICAM-1) functions via its ligands, the leucocyte integrins, in adhesion of immune cells to endothelial cells and in T cell activation. The third immunoglobulin-like extracellular domain binds integrin Mac-1 and contains a common non-conservative aminoacid polymorphism, G241R. Phenotypically, ICAM-1 has been associated with type 1 diabetes, a T-cell-mediated autoimmune disease. We assessed two independent datasets, and noted that R241 was associated with lower risk of type 1 diabetes than is G241 (3695 families, relative risk 0.91, p=0.03; 446 families, 0.60, p=0.006). Our data indicate an aetiological role for ICAM-1 in type 1 diabetes, which needs to be confirmed in future genetic and functional experiments.", "pred_label": "__label__POS", "pred_score_pos": 0.5157352089881897}
{"content": "Product Description\nPublication Date: August 05, 2019\nSource: Harvard Business School\nBy early 2019, the United States had contributed $132 billion to the Afghan reconstruction. John Sopko, in his role as the Special Inspector General for Afghan Reconstruction (SIGAR), was in charge of providing accountability for U.S. aid funding. Sopko's oversight faced severe limitations such as a growing on-budget assistance, pervasive corruption, and lack of transportation, infrastructure, and security for his staff. To fight those odds, SIGAR has implemented multiple strategies with relative success. For example, cultivating a network of sources and informants had allowed SIGAR to save the U.S. over $200 million from a fuel contract bid-rigging scheme. The SIGAR Fraud Hotline had received and reviewed over 3,200 reports. However, with the Afghan presidential elections and peace talks looming on the horizon, Sopko was wondering how SIGAR would have to adapt to a new reality that could potentially be much worse.", "pred_label": "__label__POS", "pred_score_pos": 0.9791466593742371}
{"content": "Governor Cuomo Orders All Non-Essential Workers to Work from HomeMarch 21, 2020\nOn Friday, March 20, 2020, Governor Andrew Cuomo, announced that 100% of non-essential workers are required to work from home, calling it the “most drastic measure we can take.” This is a change from the two previous orders, which called for 50% and 75%, respectively, of workers to stay home. \"We are going to close the valve. New York State is on PAUSE (Policies that Assure Safety for Everyone),\" Cuomo said. Governor Cuomo acknowledged that this would likely result in many businesses having to close. However, the executive order will not apply to those who work in essential services, including but not limited to utilities, financial institutions, grocery stores, and pharmacies. The Empire State Development Corporation has issued guidance on what “essential businesses” are. That guidance can be found at https://esd.ny.gov/guidance-executive-order-2026.\nThis order comes as the number of New Yorkers infected with COVID-19 surpassed the 7,100 mark. The actual number is likely much higher given that many people have not yet been tested. The order’s purpose is to slow the spread of the virus, while attempting to lighten the stress on New York’s medical infrastructure.\nGovernor Cuomo also asked New Yorkers to remain at home “to the greatest extent possible” and banned all non-essential gatherings of any size. He also mandated that all people should stay at least six feet away from other people when they are out in public (while engaging in solitary activities like running or walking).\nThe order is set to go into effect on Sunday night and Governor Cuomo noted that businesses will be fined for non-compliance, but that individuals would not be sanctioned.\nWe will continue to update this as more information becomes available. In the meantime, if you have questions regarding any aspects of employment law and any implications the COVID-19 virus has caused or will cause to your place of business, feel free to contact Thomas B. Wassel at (516) 357-3868 or via email at\ntwassel@cullenllp.com, James G. Ryan at (516) 357-3750 or via email at jryan@cullenllp.com, or Hayley B. Dryer at (516) 357-3745 or via email at hdryer@cullenllp.com.\nPlease note that this is a general overview of developments in the law and does not constitute legal advice. Nothing herein creates an attorney-client relationship between the sender and recipient.", "pred_label": "__label__POS", "pred_score_pos": 0.9750560522079468}
{"content": "Carewatch, one of the UK's leading home care providers, has just announced 200 new job vacancies via their website.\nCarewatch has local branches located across the UK, with vacancies available for Care Workers, Care Coordinators and Supervisors.\nTheir recent recruitment drive is part of a planned expansion, driven by Britain’s rapidly ageing population. It’s estimated that over half a million people in the UK currently receive personal and/or practical care at home – a figure which is set to rise, along with the age of the general populace.\nThe surge in demand for home care also reflects the public’s perception of the care sector, with home care often seen as a preferable alternative to residential care, because it allows people to remain in their own homes and retain greater control over their day-to-day lives.\nWorking within the home care sector provides a rewarding role which can make a real difference in people’s lives. The majority of vacancies available at Carewatch are for entry-level Care Workers, who visit local residents in their own homes to help with everyday tasks, such as getting dressed, washed, preparing meals or helping with light domestic duties.\nApplicants can view the vacancies available in their local area via the jobs section on the Carewatch website: http://www.carewatch.co.uk/home-care-jobs/", "pred_label": "__label__POS", "pred_score_pos": 0.9962603449821472}
{"content": "When people are traveling in large groups, they consider buses a safe alternative to flying. Many people rely on buses while traveling within the state and for interstate traveling. However, with the increasing number of bus accidents in the U.S, it’s evident that buses are not always safe. In 2019, U.S. registered 2,734 fatal crashes involving buses and large trucks; 3,087 people died in the crashes. According to the same report, 60,818 people suffered injuries in crashes involving buses, and 122,331 vehicles were damaged in crashes involving buses and large trucks. California, Florida, and Texas record the highest numbers of bus accidents and fatalities. If you or a loved one suffers injuries in a bus accident, Los Angeles Personal Injury Attorney can help you seek compensation.\nCauses of Bus Accidents\nThere are numerous causes of bus accidents in the U.S. Bus accidents could involve other vehicles, pedestrians, or passengers. Rollover bus accidents are also common.\nThe leading causes of bus accidents in California are:\nPoor visibility due to adverse weather conditions Negligent driving including distracted driving Collision with Other Vehicles Bus driver errors Poor road conditions Defective vehicle manufacturing Poor maintenance vehicle Driving under the influence of alcohol or drugs Poor visibility due to adverse weather conditions\nOn February 22, 2020, 3 people died while another 18 suffered injuries in a Southern California charter bus accident. According to the North County Fire and Protection District, which responded to the accident, the accident occurred when the bus lost control. The bus swerved and lost control amidst heavy rains in the area. When the driver lost control of the bus, the bus went over the side of an embankment.\nDistracted Driving\nJust like other drivers, bus drivers could also get distracted and end up causing accidents. The common causes of distraction for bus drivers include talking on the phone while driving, eating, or operating the radio while driving. At times, bus drivers are more prone to distractions than regular vehicle drivers. For instance, tour bus drivers could get distracted while trying to coordinate passengers on a tour bus. School bus drivers have a hard task of monitoring children, and this could lead to distraction. Municipal bus drivers could get distracted while ensuring that all passengers are safe while trying to answer passengers' questions and concerns.\nCollision with Other Vehicles\nIt's common for bus accidents to occur when buses collide with other vehicles like trucks or regular vehicles. Recently, ten people died when a truck collided with a bus carrying students in Glenn County. The accident occurred in Northern California when a FedEx tractor-trailer slammed into a bus carrying more than 40 students. The crash was explosive and left more than ten people dead. Most people were able to escape from the bus through an open window before the bus burst into flames. Massive flames devoured the bus and the truck after the accident, followed by two major explosions. The survivors could only look on knowing that some of their counterparts were still stuck on the bus.\nAt times, it’s not always easy to establish the cause of a bus accident. For instance, in a California tour bus accident on September 19, 2020, authorities could not identify the accident's actual cause. The crash occurred near Shandon, leading to one person's death, while seven others suffered injuries.\nIn circumstances where the cause of a bus accident is not obvious, it can be hard to establish liability. The parties involved in the accident might be quick to deny liability in the accident. However, if you have a competent personal injury attorney, you can get the compensation you deserve. An attorney will gather the necessary evidence for your case to help establish liability.\nSchool Bus Accidents\nIn addition to tour bus accidents, California also records a high number of school bus accidents. According to tabulations made by the National Safety Council (NSC) school bus-related, accidents led to the death of 118 people in 2018 in the entire U.S. NSC obtained the data from the National Highway Traffic Safety Administration (NHTSA). When NHTSA is documenting school-bus accidents, it considers any vehicle used as a school bus to be involved irrespective of the vehicle's body design. Many school bus accidents involve children getting in and out of school buses.\nSchool bus transportation is one of the safest modes of transportations in the United States. Every year in the U.S, more than 450,000 public school buses transport 23.5 million students to and from school. The school buses cover more than 4.3 billion miles every year to transport children to and from school or school trips and other related activities. Compared to other forms of transportations, students are much safer riding in school buses. The fatality rate for school buses stands at 0.2 fatalities per 100 million VMT (Vehicle Miles Traveled). The fatality rate for other vehicles stands at 1.5 fatalities for 100 million VMT. Therefore, as much as school bus accidents are common in California, school buses remain an ideal form of transportation.\nThe improvement of the safety of school buses is mainly due to the requirements set by California's Department of Transportation. The requirements revolve around the compartmentalization of school buses and the installation of lap belts. Compartmentalization entails creating a protective envelope using closely placed seats with high energy-absorbing seat backs. This design helps to protect bus occupants in case of an accident.\nAccording to a report issued by NHTSA, 301 school-going children died in school bus accidents between 2006 and 2015. Of the 301 deaths, 54 involved occupants of school vehicles, while 137 were from other vehicles. The deaths also included 102 pedestrians and eight pedal cyclists. According to this report, there were more fatalities in schoolchildren occupying other vehicles than children occupying school buses.\nOther facts revealed by the report from NHTSA are:\nOver the last ten years, there were 1,172 fatal accidents involving school vehicles in the United States. The majority of the children involved in school bus accidents were between the ages of 5 and 13. The majority of the accidents occurred in the early mornings when children report to school or in the evenings when students were leaving school.\nIf your child suffers injuries in a school bus accident due to another party's negligence, a competent personal injury attorney can help you seek compensation.\nOther Bus Crashes Statistics in the United States\nNearly every week, a bus accident occurs in the United States. The NTSB’s study conducted a study on Curbside Motorcoach Safety in 2011. The study focused on the thriving curbside business and highlighted the United States' perspective and general data on the motorcoach and bus industry. According to the study, researchers observed that commercial vehicles like buses have more risk of involvement in fatal accidents. If bus accidents involve other vehicles, pedestrians, or bicyclists, bus drivers and passengers are safer than pedestrian or regular vehicle occupants.\nThe study further revealed that in 2009, bus occupants' fatality rate stood at 45 deaths for every 100,000 bus accidents. If the bus accident involved other vehicles, passenger vehicle occupants' fatality rate was 251 deaths for every 100,000 accidents. Due to the large number of buses, passenger vehicle occupants are more likely to suffer injuries and fatalities if a bus collides with a smaller vehicle.\nThe University of Michigan conducted a study on motor carrier type and driver’s history in fatal bus accidents in 2010. The researchers noted that around 63,000 buses got involved in accidents every year. Around 14,000 bus accidents resulted in a severely injured individual, and around 325 of the accidents resulted in fatal injuries. The study revealed that intercity buses were 1.9 times more susceptible to involvement in an accident. The study also revealed that charter buses have a higher likelihood of driver errors than other buses.\nThe Journal of Safety Research researched in 2012 on risk factors associated with bus accident severity in the U.S. The research revealed that by some means, buses are not safer than regular cars. According to the research, bus accidents contributed to a small percentage of accidents in the U.S.(0.6%). However, the number of bus crashes for a million passenger miles stood at 3.04. This was comparable to vehicle accidents for a million passenger miles, which stood at 3.21.\nHowever, the study mainly focused on the traits of bus drivers involved in bus accidents. Novice or inexperienced drivers increased the risk of bus accident severity. Accident severity also increased in bus drivers of more than 55 years, with the highest risk of drivers above 65. The majority of drivers involved in severe bus accidents do not portray risky or careless driving behaviors. Only around 4% of bus drivers involved in bus accidents have a history of serious offenses like drowsy driving, speeding, or driving while intoxicated.\nCommon Injuries in Bus Accidents\nWhen a bus accident occurs, injuries are often catastrophic. Unlike passenger vehicles, buses don't have certain safety features like airbags and safety belts. Therefore, when an accident occurs, bus occupants might be ejected from the bus or fall on the bus floor. Some of the typical injuries that you might suffer in a bus accident are:\nSpinal Cord and Head Injuries\nBus occupants might experience extreme forces and serious traumas in case of an accident. A passenger's head might smash into the bus seats or whip around violently, leading to severe head injuries. If you experience a blunt force trauma in a bus accident, you could sustain traumatic brain injuries. Other likely injuries include whiplash and spinal cord injuries. Victims of bus accidents could face a lifetime of permanent paralysis.\nBroken Bones\nIt's common for victims of bus accidents to suffer broken bones. For instance, if a bus stops abruptly or hits an object, the passengers might fall and suffer fractures and broken bones. The fractures may range from simple dislocations to extensive broken bones that would call for extensive treatment. Severely broken bones could result in permanent disability, while others might call for surgery as the only treatment option.\nCuts and Lacerations\nVictims of bus accidents might also suffer cuts and lacerations after an accident. Most buses have sharp metal benches and multiple glass windows. Therefore, in case of an accident, bus passengers might sustain cuts from the sharp glasses from the bus windows. Deep cuts and lacerations could lead to excessive blood loss; if a victim does not seek immediate treatment, excessive bleeding could lead to death. Cuts and lacerations could also lead to permanent scarring and disfigurement. If lacerations become infected, mainly when left untreated, they might be life-threatening.\nInternal Injuries\nAs the body absorbs the force resulting from a bus accident, internal injuries might occur. Some of the common internal injuries that you might suffer in a bus accident are internal hemorrhaging, punctured lungs, kidney damage, and liver lacerations. Internal injuries might not have obvious symptoms immediately after the accident. The symptoms might show up much later; it is important to undergo check-up even if you do not have visible injuries. You might have suffered internal injuries, and if left untreated, the injuries might be fatal.\nPotentially Liable Parties in a Bus Accident\nWhen a bus accident occurs, several parties are likely to be liable. It's not always easy to establish liability in a bus accident. It's important to seek the assistance of an experienced attorney. An attorney can help you to establish the liable party from which to seek compensation. Some of the potentially liable parties in a bus accident are:\nTour bus operator if the accident involves a tour bus Bus driver Bus driver supervisor School bus operator if an accident involves a school bus Charter bus operator in the case of a charter bus Other vehicle drivers if an accident involves other vehicles Bus maintenance company State, county, or city council if an accident involves a public transportation bus Bus stop property owner if an accident occurs at a bus stop Bus manufacturer Bus part manufacturer\nA bus company can be liable for a bus accident if an accident occurs due to an incompetent bus driver. Bus companies have a vital responsibility for ensuring that they hire competent and well-trained bus drivers. Hiring an incompetent bus driver who ends up causing an accident could render a bus company liable. A bus company also has the role of ensuring that buses are in good condition. Therefore, if an accident occurs due to a poorly maintained bus, the bus company might be to blame for the accident. The bus maintenance company might also be liable for failing to identify a mechanical problem, which later leads to a bus accident.\nThe bus manufacturer might be to blame for a bus accident if the accident occurs due to a manufacturing defect. Bus manufacturers have to ensure that they only release quality vehicles to the market. Manufacturers also have a role in ensuring that they issue ample warnings to consumers if a product is defective.\nSometimes, a bus accident might occur due to poor road conditions. The entity responsible for maintaining the roads might be to blame for an accident resulting from poor road conditions. These entities include state or county public entities. The plaintiff can file a personal injury lawsuit against the government to maintain roadways in good condition or fail to install proper road signage.\nIn some instances, there are multiple defendants in a bus accident. California is a comparative negligence state that apportions responsibility to the parties involved depending on the degree of fault. According to California's comparative negligence law, you can recover damages even if you're partially at fault in a bus accident.\nFor a plaintiff to seek compensation in a bus accident, he/she has to prove several elements:\nThe plaintiff has to prove that the defendant owed him or her a duty of care. It should be evident that the defendant breached his or her duty of care. The defendant’s breach of duty of care should have significantly contributed to the plaintiff’s injuries. Compensation Available in Bus Accidents\nWhen you or your loved one suffers injuries in a bus accident, no compensation can be enough to compensate you for your losses. However, it's important to seek compensation for your economic and non-economic losses. In some instances, you could also seek compensation for punitive damages if the defendant was extremely negligent. Some of the available compensation includes:\nHospital bills Medications and other medical supplies Emergency treatment Physical therapy fees In-home care Vehicle repair if the bus accident involving your vehicle Lost income Loss of consortium Loss of future earning capacity Emotional pain Pain and Suffering Court fees and Costs Loss of enjoyment in life\nYou would need the help of a personal injury attorney to help determine your claim's value and assist you in seeking compensation.\nFind a Personal Injury Attorney Near Me\nIf you have suffered injuries in a bus accident, you can seek compensation for your injuries. Los Angeles Personal Injury Attorney can guide you through the legal process and help you seek compensation. Contact us at 424-231-2013 and speak to one of our attorneys.", "pred_label": "__label__POS", "pred_score_pos": 0.8772708773612976}
{"content": "I use template matching and precise relative relocation techniques to develop a highresolution earthquake catalog for the initial portion of the 2019 Ridgecrest earthquake sequence, from 4 to 16 July, encompassing the foreshock sequence and the first 10+ days of aftershocks following the Mw 7.1 mainshock. Using 13,525 routinely cataloged events as waveform templates, I detect and precisely locate a total of 34,091 events. Precisely located earthquakes reveal numerous crosscutting fault structures with dominantly perpendicular southwest and northwest strikes. Foreshocks of the Mw 6.4 event appear to align on a northwest-striking fault. Aftershocks of the Mw 6.4 event suggest that it further ruptured this northwest-striking fault, as well as the southwest-striking fault where surface rupture was observed. Finally, aftershocks of the Mw 7.1 show a highly complex distribution, illuminating a primary northwest-striking fault zone consistent with surface rupture but also numerous crosscutting southwest-striking faults. Aftershock relocations suggest that theMw 7.1 event ruptured adjacent to the previous northwest-striking rupture of the Mw 6.4, perhaps activating a subparallel structure southwest of the earlier rupture. Both the northwest and southeast rupture termini of the Mw 7.1 rupture exhibited multiple fault branching, with particularly high rates of aftershocks and multiple fault orientations in the dilatational quadrant northeast of the northwest rupture terminus.\nCITATION STYLE\nShelly, D. R. (2020). A high-resolution seismic catalog for the initial 2019 ridgecrest earthquake sequence: Foreshocks, aftershocks, and faulting complexity.\nSeismological Research Letters, 91(4), 1971–1978. https://doi.org/10.1785/0220190309", "pred_label": "__label__POS", "pred_score_pos": 0.9193845391273499}
{"content": "An advert by Greenpeace calling for the public to petition against government fracking plans that was banned by the Advertising Standards Agency in 2015 has had its ban revoked, with the UK advertising watchdog admitting its initial ruling was wrong.\nThe ad, which first appeared in national press on 14 January 2015, stated that “fracking threatens our climate, our countryside and our water” and that “experts agree - it won't cut our energy bills”.\nIt was this claim that Lord Lipsey, who sits on the House of Lords economic affairs committee, took umbrage with. Lipsey, a fracking advocate, submitted a complaint to the watchdog claiming the ad was misleading in suggesting there is a consensus among experts that fracking would not cut energy bills.\nDespite Greenpeace providing opinions from 22 energy experts including the energy secretary, leading academics, and three spokespersons from fracking firm Cuadrilla, the ASA ruled in favour of Lipsey in May 2015 and called for Greenpeace to withdraw the advert.\nGreenpeace published an article on its site shortly after dismissing the ruling as “baseless, biased, and bonkers”, claiming the watchdog was able to quote the Prime Minister’s opinion that fracking would cut household energy bills as the only evidence of this alternative view.\nThe environmental organisation questioned the impartiality of the ASA council, stating that its chair Lord Chris Smith, has a second job as head of the Shale Task Force, a lobby group funded by fracking firms including Cuadrilla, Centrica and Total.\nGreenpeace has been campaigning for an appeal of the ruling since. Today (21 September) the ASA council, following an investigation led by its independent reviewer, overturned its original ruling stating it “was not in breach” of advertising codes of practice.\nThe watchdog admitted that the “general consensus” among most was that a meaningful reduction in energy bills was highly unlikely.\n“We acknowledged that among the material Greenpeace had provided, there were quotations indicating clearer support for the view that fracking would not reduce prices.”\n“We therefore considered the claim as it was likely to be interpreted by readers had been substantiated and was not materially misleading,” it said.", "pred_label": "__label__POS", "pred_score_pos": 0.8409808874130249}
{"content": "TIV presents at a United Nation’s Workshop on Cambodia’s Draft Science, Technology and Innovation Policy.\nTIV was invited by the United Nations Economic and Social Commission for Asia and the Pacific (ESCAP) to present on Cambodia’s Draft Science, Technology and Innovation Policy in Nov 2018. Hosted by the General Secretariat of the National of Science and Technology Council of Cambodia and attended by top policy makers including H.E Mr. Has Bunton, Secretary General of GS-NSTC, as well as H.E. Mr. Tuon Tavrak, Secretary of State, and Vice chair of National Science and Technology Council (NSTC). The main event involved a Workshop on the Draft of Cambodia’s Science, Technology and Innovation (STI) Policy 2019-2025 aimed to develop an action plan to foster innovation in the country.\nAs a distinguished speaker, TIV’s CEO painted the landscape of Cambodia’s innovation framework, and the necessary conditions that must be in place for sustainable growth. The discussion also investigated how STI can contribute to not only sustainable and inclusive development, but also how STI foster social development and environmental sustainability.\nIn conjunction with a leading Economic Affairs Officer of UN’s ESCAP, Mr. Gupta kicked off the workshop with a primer on the current state of affairs in Cambodia and provided a background on the key topics of the sessions:\nSTI environment in Cambodia – Building on Current Strengths\nVision and Scope – Aligning with National Development Goals and Promoting Inclusive Innovation\nStrategic Priorities\nAction Plan\nGovernance\nIn laying the foundation for discussion, TIV also provided their expertise with innovation ecosystems. This included discussion on how innovation can be used as a means for rapid growth when elements such as technology, entrepreneurship, risk finance, tech extension and knowledge spillovers are utilized correctly. Furthermore, TIV explored a Sources of Innovation Map, which explicated multiple origin points for new ideas and how these catalysts interact in a network of Acquisition/ Transfer mechanisms and with Users of Knowledge.\nThis initiative was part of a broader engagement wherein TIV advised UNESCAP on its mission to help draft Cambodia’s new STI policy (part of Cambodia's Rectangular Strategy Phase 4). As part of the engagement, TIV also conducted proprietary analysis on the current technology trajectory Cambodia in its report, “Rapid Assessment of Cambodia’s Innovation Ecosystem.”", "pred_label": "__label__POS", "pred_score_pos": 0.5291231274604797}
{"content": "Video of the Day\nBiting is a nuisance puppy behavior that can be corrected through consistent, positive training. Left undirected, a biting puppy will learn that it can nip, bite and mouth to manipulate her owner. Additionally, aggressive issues may develop as the dog matures. Proper training must begin immediately (as early as 6 weeks) to encourage your puppy to stop biting.\nTrain your puppy that biting is painful. Each time the pup nips you, call out \"No bite!\" and yelp (as another puppy would in her natural environment). This will communicate to your puppy that she is playing too rough. Never hurt or harm your puppy in any way.\nStop playtime and ignore your puppy. If the puppy ignores your previous response and continues to nip, state \"No bite!\" firmly and calmly. Then, remove your puppy from the room for 5 minutes. Place her in a secure area--such as an enclosed kitchen--and wait until she is calm (not whining). Then, allow her to rejoin the \"pack.\" Your puppy will soon understand that biting behavior is not allowed in her family.\nProvide safe and accessible chew toys. Alleviate puppy boredom and encourage natural canine instincts by allowing him to chew on appropriate things. While supervised, give your puppy a safe chew toy, such as a Kong toy. Consult a professional at a pet store for puppy toy recommendations. Allowing for nibble time will teach your puppy that it's OK to chew on appropriate things.\nAvoid games that encourage biting behaviors. Don't teach your puppy about tug-of-war or facilitate rough play. These games can promote dog biting and dominance issues. Don't let young children play with the biting puppy until the problem behavior is eliminated.\nReinforce positive behaviors. When your puppy plays nicely, give her plenty of praise and affection. She'll learn from your encouraging reaction that not biting pleases her pack leader. This requires that all family members follow a consistent training regimen.\nSocialize your puppy. A biting puppy would quickly be redirected by another dog or her mother if she was with her litter. Allow her to socialize with other dogs (through an obedience class or at the dog park) while she's still a puppy so she can learn about playing limits. Additionally, exercise is imperative to your puppy's obedience, happiness and health.\nPhoto Credits eHow", "pred_label": "__label__POS", "pred_score_pos": 0.9163987636566162}
{"content": "Don't Routinely Recommend Pharmacogenetic Testing for Most Patients\nYou'll see a push toward\na more personalized approach to drug therapy with pharmacogenetic testing.\nThese tests will be promoted for a laundry list of meds...but they're not ready for prime time in most cases.\nThe goal of testing is to tailor drugs and doses based on the patient's genes...to avoid or minimize toxicity and maximize efficacy.", "pred_label": "__label__POS", "pred_score_pos": 0.9562426805496216}
{"content": "Looking for a COVID-19 test?\nCareClues partner hospitals and clinics have been approved by ICMR to conduct COVID-19 RT-PCR test.\nYou need to take a high-fibre diet along with plenty of fruits, vegetables and fluids to relieve constipation. Various allopathic medicines prescribed for this condition are bulk-forming laxatives (psyllium, methylcellulose), stool softeners (docusate), lubricant laxatives (mineral oil), stimulant laxatives (aloe, cascara), suppositories (sodium phosphate, docusate) and enemas. Depending upon your symptoms and root cause, the doctor will recommend a suitable medicine. It is strongly suggested that you consult a general physician before taking any medicine.", "pred_label": "__label__POS", "pred_score_pos": 0.7587549090385437}
{"content": "Abstract\nCalcium (Ca\n2+) ions are important mediators of cellular homeostasis owing to their ability to elicit a dynamic, transient, and tightly regulated range of biochemical responses. More than a decade ago, a nonselective, Ca 2+-permeable, cationic conductance was identified in podocytes downstream of angiotensin II (Ang II) signaling, but its molecular structure remained elusive. Six years ago, transient receptor potential canonical 6 (TRPC6) mutations were found in families with hereditary FSGS, and TRPC5 and TRPC6 channels are now known as the Ca 2+ influx pathways for this previously described, nonselective, cationic current in podocytes. Ang II activation engages this Ca 2+ influx to modulate the actin cytoskeleton in podocytes. These discoveries dovetail with previously described regulation of actin dynamics by the Ca 2+-activated phosphatase, calcineurin, and the emergence of Rho GTPases as critical regulators of podocyte function in health and disease. Understanding the interconnected signaling regulated by Ca 2+ currents offers potential new therapeutic targets and highlights the notion that synergistic therapies targeting multiple levels of biochemistry may be useful in treating proteinuric kidney disease. Copyright © 2011 by the American Society of Nephrology", "pred_label": "__label__POS", "pred_score_pos": 0.6889567375183105}
{"content": "Objective:\nTo examine if the association with hypertension was different between individuals with and without insomnia symptoms.\nMethods:\nThis was a population-based, multiyear, cross-sectional study with data from the 2005–2008 United States National Health and Nutrition Examination Surveys (\nn = 12 643). Insomnia symptoms were considered if at least one of difficulty falling asleep, prolonged nocturnal awakening, or early morning awakening was reported, at least five times per month. Short sleep time (<6 h) was also considered in the insomnia definition. Ever doctor-diagnosed self-reported hypertension, self-reported current antihypertensive use, and objectively measured systolic and diastolic hypertension were examined. Results:\nThere were generally no associations between insomnia symptoms and hypertension when sleep duration was not considered in the insomnia definition and after controlling for covariates. However, there were significantly increased odds of subjective hypertension measures among individuals with insomnia coupled with short sleep time compared to individuals without insomnia after controlling for covariates [e.g. among individuals with any insomnia: odds ratio (OR), 95% confidence interval (CI) of doctor-diagnosed hypertension 1.49, 1.19–1.88; OR, 95% CI of current antihypertensive medications 1.33, 1.04–1.70]. There were no significant associations though between insomnia symptoms accompanied by short sleep time and objective hypertension measures (e.g. among individuals with any insomnia: OR, 95% CI of measured systolic hypertension 1.32, 0.87–2.02; OR, 95% CI of measured diastolic hypertension 0.96, 0.52–1.75).\nConclusion:\nInsomnia symptoms coupled with short sleep time may be positively related to hypertension, but the lack of association with objective hypertension measures suggests that there may be no true relationship present.", "pred_label": "__label__POS", "pred_score_pos": 0.800983190536499}
{"content": "JavaScript is disabled for your browser. Some features of this site may not work without it.\nMeasurement and modeling of soil CO[subscript]2 flux in a temperate grassland under mowed and burned regimes\nBremer, Dale J.; Ham, Jay M.\nSoil-surface CO2 flux (R[subscript]s), which is a large component of the carbon (C) budgets in grasslands, usually is measured infrequently using static or dynamic chambers. Therefore, to quantify annual C budgets, estimates of Rs are required during days when no direct measurements of R[subscript]s are available. Other researchers have developed empirical models based on soil temperature, soil volumetric water content ([theta]v), and leaf area index (LAI) that have provided reasonable estimates of Rs during the growing season in ungrazed tallgrass prairie. However, the effects of mowing and grazing, which are common in grasslands, on predictions of Rs from those models are uncertain. Predictions of R[subscript]s during dormancy (post-senescence to spring fire) also are uncertain. Data from a year-long mowing study, which simulated grazing, were used to refit these models. Output from the models then was compared to independent data collected from nearby prairie sites. Results showed that LAI must be included to accurately estimate R[subscript]s in mowed prairie ecosystems. When LAI was not included in the model, predicted daily R[subscript]s following mowing was nearly four times greater than measured R[subscript]s, and cumulative, annual R[subscript]s was overestimated by 95-102%. When LAI was included in the model, predictions of R[subscript]s were comparable to measured R[subscript]s in the mowing study. Annual estimates of cumulative Rs ranged from 3.93 to 4.92 kg CO[subscript]2 m[superscript minus]2. When comparing the model with independent chamber data from nearby sites, cumulative R[subscript]s during those studies was within [plus minus]9% of cumulative estimates calculated from measured R[subscript]s. The model overestimated daily R[subscript]s during a dry period, suggesting a nonlinear response of R[subscript]s to soil water content; matric potential may be more appropriate than [theta]v for modeling R[subscript]s. Data suggest that R[subscript]s, in addition to being dependent on soil temperature and soil water content, is dependent on the photosynthetic capacity of the canopy and the subsequent translocation of C belowground.", "pred_label": "__label__POS", "pred_score_pos": 0.8008393049240112}
{"content": "This volume brings together insights on the interactions between environmental change and human security in the Middle East and Africa. These regions face particular challenges in relation to environmental degradation, the decline of natural resources and consequent risks to current and future human security.\nThe chapters provide topical analysis from a range of disciplines on the theory, discourse, policy and practice of responding to global environmental change and threats to human security.\nCase studies from Morocco, Tunisia, Egypt, Turkey, Iraq and Syria provide empirical evidence, with a focus section dedicated to the critical issue of water resources and water security in the region.\nThe contributions demonstrate above all that the risks posed to human security arise through multiple and interconnected processes operating across diverse spatial and temporal scales. The complexity of these processes requires new ways of thinking and intervening. As a contribution, the current volume provides engaging insights from theory and practice for those seeking to address the challenges of environmental change.\nSource and further information: springer.com", "pred_label": "__label__POS", "pred_score_pos": 0.9893441796302795}
{"content": "Purchase/rental options available:\nAbstract:\nAs technology has advanced, scholarly communication has evolved, creating new opportunities for academic libraries to serve researchers. This article examines the current state and potential future of academic library-based publishing. The review of the literature explores the scholarly communication ecosystem as it pertains to new publishing paradigms supported by academic libraries, including the complexity of nontraditional publishing models. These models and their implications, as well as how they may be implemented, are then explored in the academic library environment. Next, survey data from nineteen academic librarians collected at the American Library Association Midwinter Meeting in January 2015 is presented. Based on the literature and the survey data, this article argues that the principle concerns for academic library-based publishing going forward include 1) the need for the dedicated and/or sustained financial models for library-based publishing initiatives and 2) the cultural and financial capital to support librarians as they further expand their knowledge and expertise to support additional publishing-related functionalities in support of these new models. Both of these concerns ultimately tie to the persistent question of perceived quality, and by extension, reputation, of library-based publishing and open access publishing more broadly.", "pred_label": "__label__POS", "pred_score_pos": 0.9786441326141357}
{"content": "As our society has changed, so has our leadership style. Command and control had its place in the industrial age, but today, we need to trust and inspire our workers.\nGain a deeper understanding of the mechanics of trust and the impact it has on leadership by registering to attend a complimentary webcast.", "pred_label": "__label__POS", "pred_score_pos": 0.7356990575790405}
{"content": "Truckers continue to deal with new challenges due to coronavirus constraints on truck stops and shipper and receiver facilities while the growing demand for medical supplies and consumer essentials continues. In some states, rest stop restaurant dining rooms are closed and takeout food is the only option. Pennsylvania, one of the major shipping lanes connecting the Midwest and the East Coast, shut-down state operated rest stops. This is posing issues for drivers who go through states like Pennsylvania--where rest is critical to ensure driver safety and supply chain efficiency. Due to these concerns, 13 Pennsylvania rest stops will be reopened today.\nTruckers are facing a slew of other constraints including:\nLastly,\ntrucking capacity is tightening due to demand to move shipments from manufacturers to retailers and warehouses, as COVID-19 is pushing consumers to deplete stores of supplies. Since February 29, the average spot market rate is up 6.1%. We are atts\nProven freight brokers helping shippers and purchasing professionals navigate the complicated world of shipping.\nArchives\nMarch 2020\nCategories", "pred_label": "__label__POS", "pred_score_pos": 0.6923507452011108}
{"content": "Arizona law defines sexual harassment as any unwanted conduct of a sexual nature, whether they are verbal advances or physical action. Some types of sexual harassment that are most commonly committed by an employer include exchanging favoritism for sexual favors, the creation of a hostile work environment of a sexual nature, and sexual advances.\nHow does Arizona Law Prohibit Sexual Harassment?\nFirst, Thatcher employers can be required to establish company policies that specifically address sexual harassment in the workplace. These must be posted in a visible area such as a break room. Matters covered by such policies should include contact information used by employees to report incidents, handling procedures for claims, and corrective measures (in the event that a claim turns out to be true).\nAdditionally, federal and Arizona laws create specific agencies which are responsible for handling sexual harassment cases. The agencies are given authority to investigate workplaces in Thatcher to determine if the incidents alleged in the complaints they receive are true. Additionally, these laws prohibit employers from firing an employee for alleging sexual harassment or taking any action in retaliation to a claim.\nHow can a Arizona attorney help?\nA claim for sexual harassment may be difficult to investigate and establish without the proper expertise in the relevant areas of law. The federal officers who investigate claims of sexual harassment are, unfortunately, often too busy to give much attention to any one claim. Accordingly, hiring a lawyer in Thatcher might be the best way to ensure that your claim is filed within the deadlines specified by Arizona for sexual harassment matters.", "pred_label": "__label__POS", "pred_score_pos": 0.65854412317276}
{"content": "A covenant not to compete typically implies that a Wisconsin employee makes an agreement not to work for any of their employer's competitors should they leave the company for any reason. These covenants are typically called \"non-compete clauses\". Employees who sign them can either receive compensation or simply be required to agree as a condition for their employment.\nWhen are Covenants not to Compete Unenforceable?\nForeseeing whether or not a judge will uphold a covenant not to compete is typically difficult. Even if the employee's interests may be significant Wisconsin courts will certainly assign great weight to a person's freedom to choose the type of employment that is suitable for them. Accordingly, only those covenants which are deemed to be reasonable will be upheld by the court. Those agreements that courts have seen to be unreasonable include those that last for an prolonged period of time or cover geographic areas around Eau Claire that are unreasonably large.\nThe agreements must also deal only with those competitors whose line of employment is reasonably related to the previous employer's. Finally, there must be a valid business interest which motivates the employer's mandating a covenant not to compete.\nDo I Need an Attorney when Dealing with a Covenant not to Compete?\nAn Eau Claire, Wisconsin lawyer can help you review the covenant before you sign any agreements that might limit your rights. The lawyer can help you in negotiating modifications or if needed, they can possibly draft a new agreement which will be acceptable to both parties. A lawyer can also render useful advice for employers who are contemplating suing an employee for breach of covenant, or they can counsel employees who have signed such an agreement.", "pred_label": "__label__POS", "pred_score_pos": 0.5079002380371094}
{"content": "Making Social Studies Concepts Tangible for Pre-K Students\nSetting the standard for critical thinking in prekindergarten is essential to prepare early learners for success in later grades. Early exposure to social studies, geography, and community concepts will lead to a strong foundation for students to inquire about the world around them.", "pred_label": "__label__POS", "pred_score_pos": 0.9997373223304749}
{"content": "Abstract\nThe testicular hilum and paratestis contain several embryologically diverse anatomic structures, including the spermatic cord, tunica vaginalis, epididymis, rete testis, and several other embryonic remnants. Several benign and malignant lesions arise from these morphologically distinct structures, and owing to their proximity, it is challenging to classify and subsequently stage these tumors. Herein, we conducted a retrospective review of the paratesticular appendageal and rete testis tumors and tumor-like lesions diagnosed at our department from 1985 to 2016. Soft-tissue lesions/tumors were excluded. A total of 146 paratesticular appendageal and rete testis tumors and tumor-like lesions were identified. Most were benign (n = 107; 73%). Adenomatoid tumor (26%) was the most common benign tumor, followed by different types of cysts (19%), mesothelial hyperplasia (18%), serous cystadenoma (5.5%), and rete testis adenoma (4%). Malignant lesions comprised 23% of the cases, with mesothelioma the most common (15%), followed by adenocarcinoma of the rete testis (4%), serous cystadenocarcinoma (2%), and papillary and clear cell adenocarcinoma of the epididymis (2%). Finally, serous borderline tumors and melanotic neuroectodermal tumor (retinal anlage tumors) comprised the remaining 4% of cases. In conclusion, a wide range of benign and malignant lesions can arise from the paratesticular region. Awareness of these lesions and their histologic spectrum is crucial to avoid diagnostic pitfalls and to allow pathologists to establish a correct diagnosis and subsequent treatment plan.\nKeywords Adenomatoid tumor Cystadenocarcinoma Malignant mesothelioma Melanotic neuroectodermal tumor Paratestis Rete testis Serous borderline ASJC Scopus subject areas Pathology and Forensic Medicine", "pred_label": "__label__POS", "pred_score_pos": 0.9343107342720032}
{"content": "Charlotte’s Web Holdings (OTCMKTS:CWBHF) (NYSEARCA:CWEB) reported its fourth-quarter earnings on March 24. For the quarter, the company missed analysts’ revenue and EBITDA estimates. On March 23, the company announced that it will acquire Abacus Health for 99 million Canadian dollars in an all-cash deal. The acquisition could expand Charlotte’s Web’s market share in the F/D/M segment to 35%. So, the acquisition of Abacus Health might have impressed investors. As of March 27, Charlotte’s Web was trading at 6.38 Canadian dollars, which represents a rise of 25.1% since reporting its fourth-quarter earnings.\nAnalysts’ lowered their target prices for Charlotte’s Web\nSince Charlotte’s Web reported its fourth-quarter earnings, PI Financial and Eight Capital have lowered their target prices. On March 26, Cantech Letter reported that Jason Zandberg of PI Financial lowered his target price from 11.50 Canadian dollars to 10.00 Canadian dollars due to its disappointing fourth-quarter performance. However, he maintained his “buy” rating for the stock. On March 27, Eight Capital lowered its target price from 13 Canadian dollars to 9 Canadian dollars.\nAs of March 27, analysts’ consensus target price was $8.54. The target price represents a 12-month return potential of 92.3% from its closing price of $4.44 on March 27. Compared to February 27, analysts’ consensus target price has declined by 43.9% from $15.21.\nMeanwhile, as of March 27, Cresco Labs (OTCMKTS:CRLBF), Curaleaf (OTCMKTS:CURLF), and OrganiGram Holdings (NASDAQ:OGI) were trading at a discount of 246.6%, 142.4%, and 113% from their respective price targets.\nAnalysts’ opinion\nFor the fourth quarter, Zandberg expected Charlotte’s Web to report revenue of $23.6 million with an EBITDA of $0.4 million, as reported by Cantech Letter. However, the company reported revenues of $22.8 million and a negative EBITDA of $10.2 million. Zandberg stated that competition in the CBD market lowered the company’s revenue growth. He also said that the lack of clarity on the regulatory front created confusion for customers. They can’t verify the quantity and quality of CBD in each of the products.\nZandberg expects Charlotte’s Web to close the acquisition of Abacus Health in the third quarter of this fiscal year. He expects the acquisition to contribute $12.7 million of sales in the last two quarters of this fiscal year. For fiscal 2020, he expects the company to report revenue of $113 million, while its adjusted EBITDA could be -$16 million. Meanwhile, for fiscal 2021, he expects the company to report revenue and EBITDA of $169 million and $28 million, respectively. As reported by Cantech Letters, Zandberg added that his estimates don’t include any improvement on the regulatory front. However, he stated that any such positives from the FDA could provide an upside to his target.\nAnalysts’ ratings for Charlotte’s Web\nThere haven’t been any rating changes since Charlotte’s Web reported its fourth-quarter earnings. As of March 27, eight analysts follow the company. Among the analysts, six recommend a “buy,” while two recommend a “hold.” In the above graph, you can see that there has been a decline in analysts’ coverage. Last month, ten analysts covered the stock compared to eight analysts currently. Let’s look at analysts’ ratings for Charlotte’s Web’s peers.\nAnalysts are bullish on Cresco Labs. All 12 of the analysts that follow the stock recommend a “buy.” Among the 11 analysts that follow Curaleaf, ten recommend a “buy,” while one recommends a “hold.” To learn more, read Analysts Cut Curaleaf’s Target Price after Its Q4 Earnings. Among the 16 analysts that follow OrganiGram, 12 recommend a “buy,” while four recommend a “hold.” My take\nIn June 2019, Nielsen predicted that the US hemp-derived CBD market could reach $6 billion by 2025. With the recent acquisition of Abacus Health, Charlotte’s Web is well-positioned to acquire significant market share. Overall, I’m optimistic about the stock. Investors with a long-term perspective should utilize the recent fall in Charlotte’s Web’s stock price to accumulate the stock.", "pred_label": "__label__POS", "pred_score_pos": 0.5960957407951355}
{"content": "Root development of Arabidopsis, Zea mays (maize) and Oryza sativa (rice) differs in both overall architecture and the anatomy of individual roots. In maize and rice, the post-embryonic shoot-borne root system becomes the major backbone of the root stock; in Arabidopsis, the embryonic root system formed by a simple primary root and its lateral roots remains dominant. Recently, several specific root mutants and root-specific genes have been identified and characterized in maize and rice. Interestingly, some of these mutants indicate that the formation of primary-, seminal-, crown- and lateral roots is regulated by alternative root-type-specific pathways. Further analyses of these unique pathways will contribute to the understanding of the complex molecular networks involved in cereal root formation.", "pred_label": "__label__POS", "pred_score_pos": 0.541958212852478}
{"content": "Knowledge regarding the movement of wild fishes provides valuable information of their spatial ecology, habitat use, and migration patterns. Research is lacking to describe movement of gars, particularly Shortnose Gars. The Sport Fish Ecology Lab is working to understand the movement of these fish and their habitats, using the following two studies to get started on tracking Shortnose Gar in their natural habitats.\nStudy 1: Evaluate wound healing rate of Shortnose Gar using specialized surgical methods to internally implant acoustic transmitters.\nIntracoelemic transmitter implantation has been shown to have limited adverse effects on fishes and is considered the best method for long-term tracking relative to gastric insertion or external attachment. Standardized surgical methods for transmitter implantation for teleost’s are well known in the literature, however, traditional techniques using a scalpel are not possible on more primitive fishes such as\nLepisosteids due to the complexity of their armored, ganoid scales. This attribute poses a unique challenge for internal implantations.\nA specialized method to breach ganoid scales of Longnose Gar was developed by Midwood et al. (2018). This procedure utilizes an electric rotary tool with a cutting blade to breach the ganoid scales and drill bit to pre-drill suture holes. To evaluate survival and initial wound healing rate of Shortnose Gar with these specialized methods, we conducted a sham surgery study at the University of Illinois Pond Facility in the summer of 2018. We had 100% survival and found that Shortnose Gar recovered from sedation in under 5 minutes and surgical wounds healed in less than 2 weeks. Findings from this study will be submitted for peer reviewed publication in 2019.\nStudy 2: Evaluate habitat use (backwater, side channel, tributary, and main channel) of Shortnose Gar in response to season, discharge, and other abiotic factors in the Lower Illinois River.\nIn 2018, we initiated a field study in the lower Illinois River near Beardstown to examine movement and habitat use of Shortnose Gar. Gar were affixed with acoustic transmitters following methods used in our sham surgery study and stationary receivers were deployed in backwaters (Lilly Lake, Muscooten Bay, Treadway Lake), tributaries (La Moine River and Sangamon River), side channels, and the main channel of the Illinois River to record fish movements. These data will provide us with valuable information about the range of individuals, their seasonal movement patterns, and habitat use. This study is ongoing and will continue into 2020.", "pred_label": "__label__POS", "pred_score_pos": 0.7074840068817139}
{"content": "Melrose MCT Oil 500g\nMedium Chain Triglycerides (MCTs) are a unique group of fatty acids have a chemical structure of 6 12 carbon chains in length. They're rarer in the diet than other fats but can have positive effects on general health, physical performance and cognitive function, and may assist with weight management.\nMCTs aren't digested and absorbed in the same way as normal dietary fats due to their shorter carbon length. Instead, they're easily digested and processed in the liver, providing immediate fuel rather than being stored as fat in the body. They have been researched extensively for their many benefits, which include:\nThe Melrose MCT range consists of varying blends of caproic acid (C6), caprylic acid (C8), capric acid (C10), and the slightly longer 12-chain MCT lauric acid (C12).\nAvailable in Original, Pro Plus or Pro Rapid.\nOriginal -\n- Fuel mental and physical performance\n- Help you get into and stay in ketosis - Supports fat burning\nPro Plus -\n- General health and endurance\n- Supports a ketogenic diet - Sustained natural energy\nPro Rapid -\n- Mental and physical performance\n- Supports a ketogenic diet - Rapid natural energy - Helps provide fuel for the brain", "pred_label": "__label__POS", "pred_score_pos": 0.8517268300056458}
{"content": "Dr Tim Edensor 1 1Melbourne University\nThis paper will introduce the session by sketching out what geographers might focus on in considering how we can account for the vital role of colour in space, place and landscape. I suggest that we first need to explore the values, aesthetics and symbolic meanings that are mobilised around colour in different, highly situated cultural contexts, and how this shapes both the remaking and reading of the material world. Secondly, I focus on how colour is invariably more than representational, stimulating affective, emotional and sensory responses that are often beneath conscious apprehension. In considering these themes, I subsequently look at how power is manifest through colour and examine how a more consciously applied politics of colour might contribute to a redistribution of the sensory across space.\nBiography:\nPrincipal Research Fellow, Geography, Melbourne University, tim.edensor@unimelb.edu.au", "pred_label": "__label__POS", "pred_score_pos": 0.7069187164306641}
{"content": "As an international city, Hong Kong serves as the hub of cross-border transactions and legal disputes. Every day, legal practitioners and business people in Hong Kong are involved in cross-border legal matters, such as private international law, cross-border M&A, and international arbitration.\nThe Cross-Border Legal Issues Dialogue Seminar Series is the key initiative of the Centre for Comparative and Transnational Law 比較法與跨國法研究中心 (CCTL) -Private International Law Group by CUHK LAW to provide a forum for practitioners, academics, the business community and the general public to engage in a dialogue on various issues arising from cross-border legal matters. The Dialogue invites leading practitioners and academics to speak on a regular basis on topics related to cross-border legal matters and to contribute to research projects conducted at CUHK LAW. The Dialogue aims to become the leading forum in Asia for the exchange of views and ideas in the field.", "pred_label": "__label__POS", "pred_score_pos": 0.9881652593612671}
{"content": "Public hospitals in Ontario are operating in an increasingly complex and highly regulated environment. In this environment, hospitals are required to meet their obligations as not-for-profit corporations, including addressing governance, compliance and business operations issues. the following resources are intended to assist hospitals in understanding and complying with these obligations.\nPlease note: Important OHA member resources are available on this page. To access these resources, members are required to sign in through the Log in at the top of the page.", "pred_label": "__label__POS", "pred_score_pos": 0.982866644859314}
{"content": "Xanax Pharmacology\nFollowing oral administration, alprazolam is quickly absorbed and metabolised by the body. Peak concentrations in plasma (proportionate to the dose) occur approximately 1 to 2 hours after ingestion. The metabolites 4-hydroxyalprazolam and a-hydroxyalprazolam are chiefly responsible for alprazolam’s metabolisation.\nThe precise mechanism of action in alprazolam is not currently known; merely that it enhances the body’s GABA, the CNS’s primary inhibitory neurotransmitter. Alprazolam is believed to act by strengthening (rather than adding to) the body’s existing GABA, which quietens the neurons in the brain, thereby calming the brain and subsequently the mind.\nAlprazolam and its metabolites are largely excreted in urine.", "pred_label": "__label__POS", "pred_score_pos": 0.9913384318351746}
{"content": "First, the budget: There is $83.5 billion in the state’s budget for the 2017-18 fiscal year. While this is slightly higher than the previous year, predicted budget shortfalls of $1.3 billion in 2018 and $1.9 billion in 2019 have made lawmakers cautious about future spending plans. Given that about a quarter of the state’s appropriations are on K-12 and higher ed, spending proposals for education will be highly scrutinized during the current session and beyond.\nAffordability: Making college more affordable for Florida students and families remains a prominent policy issue for state lawmakers, including Governor Rick Scott. Tuition at Florida public colleges and universities have stayed the same over the past four years, and this year, plans to reform state financial aid and tuition policies have emerged.", "pred_label": "__label__POS", "pred_score_pos": 0.9684112668037415}
{"content": "Tuskegee University has received approximately $1.83 million in Coronavirus Aid, Relief and Economic Security (CARES) Act funds to support the emergency needs of enrolled students resulting from the COVID-19 pandemic and disruption of academic programs university operations. These funds will be distributed to students upon completion of the Tuskegee Emergency Fund Application available online. The University has established a Student Emergency Fund Committee to review all applications and determine the allocation amounts to students.\nEmergency funds can be allocated to cover the following: technology, travel, utilities, vehicle expenses, child-care, course materials, gas, groceries, medical, and rent. As of May 8, the Student Emergency Fund Committee has received more than 1,300 applications and funded more than 850 students. This process will continue over the next twelve months or until all funds are exhausted. Students with emergency needs must complete an online application at http://www./studentemergencyfundapplication.\nWho is eligible?\nAll current degree-seeking students (graduate, undergraduate, VETMED) enrolled in Spring 快2彩票, Summer 快2彩票 and Fall 快2彩票 affected by the COVID-19 pandemic and are Title IV eligible (a completed 2019-20 FAFSA on file or eligible to file a FAFSA) are eligible for CARES Act funds. Students who do not meet the CARES Act requirements may be eligible to receive other institutional funds. Please contact kholland@.\nHow much funding is available?\nTuskegee University was awarded a fixed amount of funds to be allocated to students over one-year; and amounts to students will vary, ranging from $400 to $1,000, depending on each student’s request and economic circumstances.\nWhat types of expenses are covered by the CARES Act emergency funding?\nCARES Act funding provides financial assistance with expenses related to the disruption of campus operations due to COVID-19 (e.g., food, housing, course materials, transportation, technology, or health care).\nHow do I apply for CARES Act funding?\nStudents must complete the COVID-19 Emergency Fund Request Form. Funds will be awarded on a first-come, first-served basis. Please review the eligibility information below to determine your eligibility to receive CARES Act funds.\nDo I need to complete a FAFSA to receive CARES Act funds?\nNo, all students must be Title IV eligible to receive CARES act funds. However, having a FAFSA on file is evidence of Title IV eligibility. Students without a FAFSA will be required to demonstrate their Title IV eligibility through alternate means and should contact rdouglass@.\nHow do I know if I am eligible to file a FAFSA?\nThe eligibility criteria to file a FAFSA, as outlined in Section 484 of the Higher Education Act (HEA), include but are not limited to the following:\nCan undocumented students and international students receive funds under the CARES Act?\nNo, international and undocumented students are not eligible to receive CARES Act funds. However, they may be eligible to receive emergency funds from other institutional sources. Please contact kholland@.\nI am enrolled in an online program; do I qualify for CARES Act funds? You are not eligible for CARES Act funds if you were enrolled exclusively in an online program on March 13, 快2彩票. However, if you were enrolled in a combination of online and in-person classes, you are eligible. Do I need to be meeting satisfactory academic standards to receive Cares Act funds?\nYes, to be eligible for CARES Act funding, you must meet Satisfactory Academic Progress (SAP) standards in accordance with Tuskegee’s financial aid rules and regulations. Contact rdouglass@ for further clarification.\nI have an outstanding tuition/housing balance for the current semester; would these funds be applied to that balance?\nNo, the funds will be sent directly to you.\nHow long before I receive funds? Requests will be processed on a first-come, first-served basis. How will I be notified that my request has been approved? You will receive notification from the Division of Student Affairs and your check will be sent to the address on your Emergency Funds Application. Can these funds affect other aid that I have already received? No, CARES Act funds will not reduce your financial aid award.", "pred_label": "__label__POS", "pred_score_pos": 0.922195553779602}
{"content": "Abstract\nPhotosynthesis is the source of our food and fiber. Increasing world population, economic development, and diminishing land resources forecast that a doubling of productivity is critical in meeting agricultural demand before the end of this century. A starting point for evaluating the global potential to meet this goal is establishing the maximum efficiency of photosynthetic solar energy conversion. The potential efficiency of each step of the photosynthetic process from light capture to carbohydrate synthesis is examined. This reveals the maximum conversion efficiency of solar energy to biomass is 4.6% for C3 photosynthesis at 30 °C and today's 380 ppm atmospheric [CO\n2], but 6% for C4 photosynthesis. This advantage over C3 will disappear as atmospheric [CO 2] nears 700 ppm. ASJC Scopus subject areas Biotechnology Bioengineering Biomedical Engineering", "pred_label": "__label__POS", "pred_score_pos": 0.581183910369873}
{"content": "When asked to predict the outcome of 2020, I’m sure many would not have responded with a global pandemic! But alas, as we reach our eighth month of lockdown measures, the new Coronavirus has disrupted both our daily lives and the judgment process, as I have clearly seen in the analysis of Registry Trust data on monetary judgments in the UK and Ireland.\nAs part of Registry Trust’s aim to share ‘public data for the public good’ to inform responsible lending and borrowing, we are working hard to understand the correlation between the trends we are seeing in the data coming out of our Register of Judgments, Orders and Fines, and the wider economy. I therefore wanted to take the opportunity to take a look at the statistics we have published for the first three quarters of the year to identify how lockdown measures have altered judgment levels, the potential reasons why, and what this means in a wider context. It must be noted that the measure of judgments has not been adjusted for the population, therefore comparison between regions may be skewed by population density.\nNot only has COVID-19 had detrimental effects on individual health and health providing services, its economic impact has the potential to be more financially damaging than the 2008 Global Financial Crisis. 2020 has been characterised by significantly reduced judgment rates across every region compared to 2019, therefore comparison to prior years would not tell much of a story, other than that things have significantly changed.\nWithin England and Wales, judgment levels remained steady from January to March, followed by a drastic decrease in across all regions in April, continuing through May and June. May 2020 was characterised by the lowest level of judgments in 2020, with the South East registering only 4,250 judgments, compared to 14,074 in May of the previous year. Likewise, May 2020 registered 1,633 judgments in Wales, compared to 6,508 the month prior, and 6,545 the year prior.\nThe maps above highlight a distinct correlation between the introduction of lockdown measures and reduced judgment levels. As discussed in an earlier blog, this is attributed to protective measures implemented by the government to protect the most financially vulnerable, and due to the partial closing of courts thus limiting the number of judgments processed. This decline is not attributed to improved financial stability within regions, with the pandemic expected to widen the financially stable: unstable dichotomy. It is possible that judgment levels will further increase in regions with already high pre-pandemic levels.\nInterestingly, as lockdown measures eased on July 4th and society begun its journey to normality, judgment levels rose. Between June and October, judgment levels more than doubled in all regions excluding the North East and East Midlands. Judgments between June and July rose particularly fast, potentially due to a backlog of judgments in the courts.\nNote: the scale differs to that of England and Wales due to the reduced number of judgments.\nSimilar is the story with Scotland and Northern Ireland who entered their first day of lockdown on March 24 and 28 respectively. In Northern Ireland, judgment levels decreased from 715 in March to 184 in April, reaching only 395 judgments in October (still 45% lower than March levels).\nJudgment levels in Scotland in July reached 1,714 compared to only 162 the previous month, and 1,216 in the following month. As with England and Wales, this could be attributed to a backlog of judgments once the courts re-opened with the loosening of COVID restrictions. Judgment levels from August to September decreased to 1,186, followed by an increase of 100 to 1,286 in October. With the courts back open and processing a backlog of judgments, it is possible this rise in October is attributable to an increase of consumer indebtedness created though the pandemic.\nUnfortunately, the second national lockdowns will carry a second wave of financial hardship for many. While policy makers continue to implement protective measures through schemes such as Furlough, it is expected that levels of indebtedness will rise as consumers become unable to pay their debts that were exacerbated through the pandemic.\nIt is therefore more important than ever to become financially fit, be that through reduced spending or through receiving loans from reputable and low-risk sources only.\nTo help keep everybody informed, we are planning to use our granular judgment data to monitor regional recovery from COVID-19, and will update the Financial Stress Tracker as we go.", "pred_label": "__label__POS", "pred_score_pos": 0.6441099643707275}
{"content": "Ports in a Storm Del av serien Kort om boken Innbundet\nBok med hardt omslag.\nHeftet bok med mykt omslag.\nKartonert\nBok med tykke, stive sider.\nE-Bok\nDigitalt format. E-bok kan leses i ARK-appen eller på Kindle. Bøkene kan også lastes ned fra Din side.\nNedlastbar lydbok\nDigitalt format. Nedlastbar lydbok kan lyttes til i ARK-appen. Bøkene kan også lastes ned fra Din side.\nDigikort lydbok\nLydbok på digikort. Krever Digispiller.\nCompact Disc\nLydbok eller musikk på CD. Krever CD-spiller eller annen kompatibel avspiller.\nVinyl\nVinylplate. Krever platespiller.\nDVD\nDVD-film. Krever DVD-spiller eller annen kompatibel avspiller.\nBlu-ray\nBlu-ray-film. Krever Blu-ray-spiller eller annen kompatibel avspiller.\nFri frakt- på kjøp over 249,- Alltid bytterett- Norges beste. Bytt uten kvittering. Om Ports in a Storm\nIn Ports in a Storm a team of Harvard Kennedy School scholars focus diverse conceptual lenses on a single high-stakes management taskenhancing port security across the United States. Their aims are two: to understand how a public manager might confront that complex undertaking, and to explore the similarities, differences, and complementarities of their alternative approaches to public management.The book takes as its pivot point the singular case of U.S. Coast Guard Captain Suzanne Englebert and her leadership of efforts to secure America's ports after the September 11 attacks. The Coast Guard had always been responsible for securing America's ports and coastline. But now it was tasked with safeguarding these critical, complex, and vulnerable assets during a time of war, a job it clearly could not handle alone. Ports in a Storm considers the monumental challenge of driving rapid change in a complex system involving hundreds of private organizations and scores of government agencies with their operations intricately intertwined. The book examines Englebert's actions from varied conceptual vantage points, sometimes critiquing questionable calls but more often celebrating her initiative, creativity, persistence, and skill.The authors use the Coast Guard episode as a testing ground for the eclectic intellectual constructs they have been developing to guide public managers. Instead of starting with theory and searching for examples that fit, they begin with the concrete and then harness scholarship to the service of better practice. And rather than mimic management principles from the business world, they tailor their approach to the very different challenges of managing in a public sector context. The volume allows readers in both the scholarly and practical worlds to see how the theories measure up.Contributors, including the two volume editors, are Robert D. Behn, John D. Donahue, Archon Fung, Stephen Goldsmith, Elaine Kamarck, Herman B. Leonard, Mark H. Moore, Malcolm K. Sparrow, Pamela Varley, and Richard Zeckhauser.", "pred_label": "__label__POS", "pred_score_pos": 0.5034782886505127}
{"content": "According to Dr Fong, headaches are common among children and the number of children having headaches increases with increasing age. A non-pharmacological approach is the first-line treatment strategy for headache, includes: 1. identifying headache patterns by using a headache diary and minimising possible precipitating factors to the headache. 2. teaching the child and family lifelong strategies in managing headaches, including relaxation, a health and balanced diet, good sleep hygiene and behaviour modification.", "pred_label": "__label__POS", "pred_score_pos": 0.9090714454650879}
{"content": "Jihyeon Yu, Luhua Tu, Saminathan Subburaj, Sangsu Bae & Geung-Joo Lee\nPlant Cell Reports (2020) - Published: 21 September 2020\nKey message\nWe obtained a complete mutant line of\nPetunia having mutations in both F3H genes via Cas9-ribonucleoproteins delivery, which exhibited a pale purplish pink flower color.\nABSTRACT\nThe CRISPR-Cas system is now revolutionizing agriculture by allowing researchers to generate various desired mutations in plants at will. In particular, DNA-free genome editing via Cas9-ribonucleoproteins (RNPs) delivery has many advantages in plants; it does not require codon optimization or specific promoters for expression in plant cells; furthermore, it can bypass GMO regulations in some countries. Here, we have performed site-specific mutagenesis in\nPetunia to engineer flower color modifications. We determined that the commercial Petunia cultivar ‘Madness Midnight’ has two F3H coding genes and designed one guide RNA that targets both F3H genes at once. Among 67 T 0 plants regenerated from Cas9-RNP transfected protoplasts, we obtained seven mutant lines that contain mutations in either F3HA or F3HB gene and one complete mutant line having mutations in both F3H genes without any selectable markers. It is noteworthy that only the f3ha f3hb exhibited a clearly modified, pale purplish pink flower color (RHS 69D), whereas the others, including the single copy gene knock-out plants, displayed purple violet (RHS 93A) flowers similar to the wild-type Petunia. To the best of our knowledge, we demonstrated a precedent of ornamental crop engineering by DNA-free CRISPR method for the first time, which will greatly accelerate a transition from a laboratory to a farmer’s field.\nSee: https://link.springer.com/article/10.1007/s00299-020-02593-1", "pred_label": "__label__POS", "pred_score_pos": 0.7600558400154114}
{"content": "Abstract\nUsing a field experiment in collaboration with Yelp across 3,218 businesses in the personal care industry, I empirically explore the value of competitor information on firms’ pricing decisions. I find that competitor information improves firms’ pricing, but even when it is valuable and easily attainable, firms appear to suffer from attentional costs in realizing its value. These findings suggest that inattention may be a key barrier that leads firms to fail to realize gains from even readily accessible data.\nSpeaker bio\nHyunjin Kim is a doctoral candidate in the strategy unit at Harvard Business School.\nHer research explores how the increasing availability of data in the digital economy shapes firm strategy and the nature of market competition.", "pred_label": "__label__POS", "pred_score_pos": 0.9976639151573181}
{"content": "The FCA has published an\nevaluation paper on reducing barriers to entry into the UK banking sector. In its paper, the FCA evaluates the impact that the 2013 reforms to the authorisations process and a shift in approach to the prudential regulation of banking start-ups, has had on firms.\nKey findings from the evaluation include:\nthere is a more efficient authorisations process; the rate of entry into the UK banking sector is higher than before the 2013 review; the increase in entry has in turn led to a greater range of product offerings in the retail market and benefits for consumers; and there has not yet been a substantial change to concentration in the retail banking sector, nor has the FCA got evidence of significant competitive responses by incumbent banks.", "pred_label": "__label__POS", "pred_score_pos": 0.8616951107978821}
{"content": "The three-dimensional structure of a catalytic antibody (1F7) with chorismate mutase activity has been determined to 3.0 A resolution as a complex with a transition state analog. The structural data suggest that the antibody stabilizes the same conformationally restricted pericyclic transition state as occurs in the uncatalyzed reaction. Overall shape and charge complementarity between the combining site and the transition state analog dictate preferential binding of the correct substrate enantiomer in a conformation appropriate for reaction. Comparison with the structure of a chorismate mutase enzyme indicates an overall similarity between the catalytic mechanism employed by the two proteins. Differences in the number of specific interactions available for restricting the rotational degrees of freedom in the transition state, and the lack of multiple electrostatic interactions that might stabilize charge separation in this highly polarized metastable species, are likely to account for the observed 10(4) times lower activity of the antibody relative to that of the natural enzymes that catalyze this reaction. The structure of the 1F7 Fab'-hapten complex provides confirmation that the properties of an antibody catalyst faithfully reflect the design of the transition state analog.", "pred_label": "__label__POS", "pred_score_pos": 0.5301481485366821}
{"content": "Mark HannaRetired Agricultural EngineerIowa State University Extensionhmhanna@iastate.edu\nSnow removal on an acreage lane can be challenging, particularly during and after a big winter storm. Unless your pickup truck has a blade, most equipment is tractor-mounted. Choosing equipment that’s most effective for snow removal often depends on the size and type of tractor, or other unit powering the equipment. Other things being equal, the reduced mechanical complexity of a blade is less costly than a blower. Blades are typically associated with units larger than a lawn mower-type tractor. Front end loader equipment costs may be in between those of blades and blowers although the cost of a loader is often shared by other uses.\nAre there other needs for a small tractor (and perhaps front-end loader) such as tilling, planting or livestock chores on the acreage? Access to an inexpensive older tractor with a rollover protective structure (ROPS) allows the use of a blade with an existing three point hitch. A front-end loader may already be required for moving manure or feed for livestock. In addition, many acreage owners find a front-end loader saves back-breaking work with other tasks.\nDownsides to using a larger tractor than needed for acreage operations include the initial cost and long-term maintenance. Acreage owners often have more than enough internal combustion engines to maintain. Adding an inexpensive older tractor can generate significant repair and maintenance costs (filters, tires, fluid changes, etc.). A tractor without ROPS should generate a ‘red flag’ for use, particularly on slick and uneven surfaces. If you have other uses for a larger tractor (e.g., 30 hp or greater) using a blade or loader is economical if you’ve got places to push the snow. Leaving a part of a snow pile on a right-of-way is hazardous for traffic. Blades are available as an attachment on the front of some loaders rather than mounting the blade on the rear of the tractor.\nIf acreage needs are smaller and mainly for lawn mowing and snow removal, a larger lawn-mower type tractor (around 20 hp) is often more economical even though a blower rather than a blade-attachment is needed for significant amounts of snow removal. The blower will more easily direct where snow is deposited than a blade.\nUse safety in any snow removal operation.\nConsider tractor and vehicle stability on slick surfaces. Stop power to the blower and engine before attempting to clean the discharge. Maintain the engine so it can easily restart after cleaning. Don’t get under a hydraulically supported loader without mechanically blocking it first.", "pred_label": "__label__POS", "pred_score_pos": 0.7266470193862915}
{"content": "The job market is dramatically changed in 2020 due to the novel coronavirus. The pandemic has taken out many people’s jobs, leaving them to look for opportunities in the market. What made the situation worse is the declining economy, due to which the total unemployment rate has reached 7.9.\nShould you pass on a job offer in this crisis? Can passing a job offer hurt your career?\nThe current circumstances would not recommend to anybody to pass on a job offer. However, some candidates pass on a job offer to hold a good job opportunity better than the previous one. The only essential aspect to analyze the reasons for which people pass on a job offer.\nWhat if the job offer is a downgrade?\nThere are several situations when job candidates realize that the current job offer is a downgrade to their position and pay. Will they accept the job offer or pass on? Unemployment is undoubtedly one of the critical aspects of our current economy; however, it does not mean you should accept the downgrade job offer.\nIt is better to pass on a job offer that downgrades your position, knowledge, and pay. If you accept that offer, you may lose your confidence and dignity to some extent.\nWhat if you have multiple job offers?\nYou can judge a better opportunity for yourself. When having more than one job opportunity in hand, you should not delay in deciding the best job opportunity. In this case, passing on a one job offer is recommended; however, the earliest you can convey the message to the HR is better.\nWhat if you are laid off due to a pandemic?\nUndoubtedly, several companies have chosen layoffs as one of the modes of cost-cutting and saving their business in this pandemic. If you have lost your job due to the pandemic, you should not pass on any job offer. You may get the job offer with low pay and below your previous designations. You can still manage the job for a few months while looking for an opportunity matching your requirements. Sometimes your talent will speak for itself in the workplace.\nWill the situation be normalized?\nYes, when the pandemic hit the world, the unemployment rate was 14, which has reduced to 7.9. We are continuously recovering collectively. However, the recovery is inevitable but will take time for sure. Therefore, while we are moving back to the growth track, we all need to examine our available options to stay afloat in the economy.\nDon’t hope for the best, Work For The Best.\nSuraj Tripathi\nSuraj Tripathi is a content marketing professional with 8 years of experience in the digital marketing industry. Covering the wide range of content genres, he is managing the digital content marketing of Saxon Global. He has expertise in breaking down the tech-related content to make it more readable and understandable by the non-tech audience.", "pred_label": "__label__POS", "pred_score_pos": 0.5080419182777405}
{"content": "December 2018\nIZA DP No. 12012: Career Lotto: Labor Supply in Winner-Take-All Markets\nAre people prone to selecting occupations with highly skewed income distributions despite minuscule chances of success? Assembling a comprehensive pool of potential teenage entrants into professional tennis (a typical winner-take-all market), we construct objective measures of relative ability and earnings projections. We find that prospective tennis professionals are attracted to right-skewed earnings distributions, independent of mean and variance. If skewness in prize money fell to zero, males would be 23% and females 5% less likely to continue pursuing a professional career, on average. Thus, winner-take-all labor markets appear to systematically encourage those with modest talents to pursue long-shot careers.", "pred_label": "__label__POS", "pred_score_pos": 0.8460792303085327}
{"content": "$26.49\n5-MTHF (also known as 5-Methyltetrahydrofolate) is a biologically active form of folic acid, which some even consider as a breakthrough in folate supplementation. This vegetarian source of 5-MTHF provides one milligram per serving. This 5-MTHF supplement by Thorne Research is an excellent source of folate for pregnant women or anyone who wants to ensure they are getting appropriate levels of folate. Folate is essential to support nerve and cardiovascular function. As with most Thorne Research products, this 5-MTHF does not have preservatives, magnesium stearate or other diluents and lubricants. This supplement has been produced without inhibiting flowing agents. Medicinal Ingredients: Each capsule contains:\nFolate (as L-5-Methyltetrahydrofolate)\n1 mg\nNon-medicinal ingredients: Microcrystalline cellulose, Hypromellose (derived from cellulose) capsule, Leucine, Silicon dioxide. Adults: Take 1 capsule one to three times daily or as recommend by a health-care practitioner. Wheat, gluten, corn, yeast, soy, egg, dairy products, artificial (colours, sweeteners, or flavours), lactose, palmitic acid, magnesium stearate, and stearic acid.", "pred_label": "__label__POS", "pred_score_pos": 0.7509752511978149}
{"content": "The economics of tobacco control in Nigeria: modelling the fiscal and health effects of a tobacco excise tax change\nThis paper examines the potential for changes in the tobacco tax to contribute to raising government revenues, reducing tobacco use, and improving public health in Nigeria. Specifically, it estimates the impact of a change in the excise tax structure and level on cigarette consumption, government revenue, smoking prevalence, net-of-tax (NOT) revenue, and the excise tax burden.", "pred_label": "__label__POS", "pred_score_pos": 0.8764041066169739}
{"content": "Bitcoin’s hashrate, or computing horsepower, has hit its highest ever level indicating that the network has never been in better shape in terms of security.\nHashrate High\nThe new milestone of 170 exahashes per second was noted by on-chain analytics provider Glassnode which added that it is a 40% increase since the halving in May.\n#Bitcoin hash rate hits a new ATH and touches 170 exahash for the first time in history on the hourly chart (24h MA).\nThat is an increase of around 40% since the halving in May, substantially adding to the security of the network.\n— glassnode (@glassnode) October 8, 2020\nThe hashrate high is not correlated with prices, however, which remain stuck in a range bound channel.\nBitinfocharts.com confirms the new peak but reports it slightly lower at 155 EH/s. It also reports that the hashrate has increased by 63% since the same time last year.\nThere was widespread fear that miners would capitulate after the halving which reduced the block reward from 12.5 BTC to 6.25 making it more expensive to produce each new coin.\nBitcoin has shed a lot of its volatility over the past month and has remained above five figures for 65 days in a row according to recent reports. The 50 and 200 weekly moving averages also remain at all-time highs, and the on-chain fundamentals such as hashrate continue to show signs of positivity.\nChart guru, Peter Brandt, stated that weekly and daily charts are flashing ‘big buy signals’ at the moment.\nIt is a major development that a global corporation is now putting $BTC onto its balance sheet. The weekly and daily charts a poised to flash a big buy signal. https://t.co/p6652SfqVc pic.twitter.com/rCoKZCY5LB\n— Peter Brandt (@PeterLBrandt) October 8, 2020\nLarge institutional-grade funds continuing to buy BTC at current levels is a bullish indication that another rally could be around the corner.\nBitcoin Price Outlook\nOn the daily timeframe, Bitcoin touched an intraday high of $10,950 a few hours ago but has still failed to break that $11k psychological barrier. The move marks a 3.8% climb from its low point of $10,550 during Thursday’s trading session.\nTrader and analyst ‘CryptoHamster’ noted the break of the pennant to the upside which could lead to a larger move over the weekend.\n— CryptoHamster (@CryptoHamsterIO) October 8, 2020\nThe rest of the crypto market is enjoying the momentum as total capitalization climbs 2.5% on the day adding $10 billion to digital assets. Ethereum has returned to $350 while Polkadot and Chainlink are making strong moves with over 8% gained on the day.", "pred_label": "__label__POS", "pred_score_pos": 0.6316424608230591}
{"content": "City and County of San Francisco Pass Good Food Purchasing Ordinance\nFOR IMMEDIATE RELEASE\nContact:\nKatie Ettman, SPUR kettman@spur.org\nSan Francisco, Calif. (August 21, 2020) — The City and County of San Francisco Board of Supervisors unanimously approved a landmark ordinance this month to introduce standards and goals for food purchasing by the Department of Public Health and Sheriff’s Department in hospitals and jails.\nThe ordinance—introduced by Supervisor Sandra Lee Fewer and approved on August 11, 2020—outlines steps for improving food purchasing over the next five years based on the Standards of the Good Food Purchasing Program. The goal is for San Francisco hospitals and jails to become certified Good Food Providers by 2023, as designated by the Center for Good Food Purchasing.\nThe Good Food Purchasing Program was established in 2012 to shift institutional food purchases across the country in alignment with five core values: environmental sustainability, valued workforce, strong local economies, nutrition and health, and animal welfare. First adopted in Los Angeles, the Program is now active in 45 institutions across the country, from the San Francisco Bay Area to Chicago to Washington DC.\nThe City and County of San Francisco spend nearly $7.5 million on food through agencies such as the Department of Public Health (hospitals) and the Sheriff’s Department (jails). This move to align food purchasing practices with the Good Food Purchasing Standards is a significant step toward a more just and sustainable food system.\nSPUR and a broad coalition of community partners have supported implementing the Good Food Purchasing Policy since 2016. The City and County’s move follows the adoption of the Good Food Purchasing Program by San Francisco Unified School District in 2016.\nKatie Ettman of SPUR commented, “Public procurement can and should support all residents. For example, using public procurement to support California agriculture has economic benefits to the state far beyond the farms growing the fruits and vegetables served. It is also a powerful strategy to support environmentally friendly agricultural practices that improve water-use efficiency, carbon sequestration, and resilience during droughts—environmental impacts that affect all Californians. Public agencies can also encourage healthier diets by expanding the options it offers when it serves food directly to people in its hospitals and jails.”\n###\nTo learn more about the Good Food Purchasing Program in San Francisco, visit: https://goodfoodcities.org/portfolio/san-francisco\nFor more data about San Francisco food procurement, see: https://www.spur.org/news/2020-08-14/good-food-all-san-francisco-hospitals-and-jails-commit-improve-food-purchasing", "pred_label": "__label__POS", "pred_score_pos": 0.5295754671096802}
{"content": "Abstract\nTo maintain structural integrity, an effective method is needed to estimate structural responses using measured displacement data. It is necessary to determine the global displacements of a structure to evaluate its condition. However, fully determining the displacements can be difficult when insufficient measured displacement data are available. In this study, the SRALD 1.0 method is introduced for estimating the internal forces of a structure with limited displacement data. The suggested method involves two stages: deformed shape estimation and structural analysis. In the deformed shape estimation stage, the deformed shape of a structure is estimated using a limited number of displacement data. In the structural analysis stage, internal forces such as bending moments and axial forces are calculated using the estimated deformed shape. To validate SRALD 1.0, numerical analyses of bridges are conducted, and the characteristics of the parameters used in the newly developed method are analyzed. The estimation results are compared with those of conventional interpolation methods. Finally, the validity of SRALD 1.0 is confirmed.\nKeywords displacement internal force interpolation SRALD 1.0 structural deformation structural health monitoring (SHM) ASJC Scopus subject areas Civil and Structural Engineering", "pred_label": "__label__POS", "pred_score_pos": 0.6192086935043335}
{"content": "Abstract\nWe incubated different radiolabeled steroid precursors with intact chub mackerel ovarian follicles to clarify the synthetic pathways of steroid hormones during vitellogenesis and following final oocyte maturation (FOM). During vitellogenesis, estradiol-17β (E2) was synthesized from pregnenolone via 17-hydroxypregnenolone, 17-hydroxyprogesterone, androstenedione, and testosterone. The physiological significance of the intermediate metabolites of E2 in the ovarian follicles was examined by comparing follicular steroidogenesis between gonochoric and hermaphroditic fish species. After vitellogenesis, the steroidogenic pathway shifted from E2 to maturation-inducing hormone (MIH) production owing to the inactivation of 17,20-lyase and the activation of 20β-hydroxysteroid dehydrogenase. Of the new steroids produced during FOM, 17,20β-dihydroxy-4-pregnen-3-one (17,20β-P) was most effective at inducing germinal vesicle breakdown in vitro. Circulating levels of 17,20β-P increased specifically around the time of germinal vesicle migration, while another FOM-specific 20β-hydroxylated progestin, 17,20β,21-trihydroxy-4-pregnen-3-one, was present at consistently low levels during FOM. These results indicate that 17,20β-P is the MIH of chub mackerel.\nAll Science Journal Classification (ASJC) codes Animal Science and Zoology", "pred_label": "__label__POS", "pred_score_pos": 0.6526039838790894}
{"content": "President Donald Trump has signed into law the Bipartisan Budget Act of 2018, a long-term budget agreement that includes extensions of lapsed tax credits for alternative fuel vehicles and refueling infrastructure retroactively for 2017.\nOn Friday, the bill, H.R.1892, was passed in the House (240-186) and the Senate (71-28) and later signed in the White House. For the alt-fuels sector, the bill includes extensions for tax credits that had expired at the end of 2016. This includes provisions for new qualified fuel cell vehicles; non-hydrogen alt-fuel vehicle refueling properties (hydrogen refueling infrastructure was already eligible for the tax credits); biodiesel and renewable diesel; second-generation biofuel producers; and two-wheeled plug-in electric vehicles (EVs).\nImportantly, the bill also reinstates the $0.50/gallon alternative fuels tax credit (AFTC). As explained by the Alternative Fuels Data Center (AFDC), part of the U.S. Department of Energy’s Vehicle Technologies Office, the incentive, which had expired on Dec. 31, 2016, is applicable to fuel sold or used through Dec. 31, 2017. The tax credit is available for “natural gas, liquefied hydrogen, propane, P-Series fuel, liquid fuel derived from coal through the Fischer-Tropsch process, and compressed or liquefied gas derived from biomass.” Read the full article here.", "pred_label": "__label__POS", "pred_score_pos": 0.8149632215499878}
{"content": "The pillar one and pillar two blueprints propose significant modifications to the international tax system, granting greater taxing rights to countries where the customers of a multinational group reside (pillar one) and adding a minimum tax on multinational group profits (pillar two). The drafts will be considered the next Inclusive Framework meeting, to be held October 8–9, at which time it is expected that the final blueprints will be made public. G20 finance ministers will then consider the pillar one and pillar two proposals at their October 15–16 meetings. The proposal will then be considered by G20 leaders at their November 21–22 meeting. The goal is to reach a global agreement on an updated international tax system by year-end.\nRegards CA Vishal Mehta\nPartner PBS Solutions www.prophetic.co.in", "pred_label": "__label__POS", "pred_score_pos": 0.6561856269836426}
{"content": "Abstract\nWe show that the gravitational wave source counts distribution can test how gravitational radiation propagates on cosmological scales. This test does not require obtaining redshifts for the sources. If the signal-to-noise ratio (ρ) from a gravitational wave source is proportional to the strain then it falls as R\n-1, thus we expect the source counts to follow dN/dρ ∝ ρ -4. However, if gravitational waves decay as they propagate or propagate into other dimensions, then there can be deviations from this generic prediction. We consider the possibility that the strain falls as R -γ, where γ = 1 recovers the expected predictions in a Euclidean uniformly-filled Universe, and forecast the sensitivity of future observations to deviations from standard General Relativity. We first consider the case of few objects, seven sources, with a signal-to-noise from 8 to 24, and impose a lower limit on γ, finding γ > 0.33 at 95% confidence level. The distribution of our simulated sample is very consistent with the distribution of the trigger events reported by Advanced LIGO. Future measurements will improve these constraints: with 100 events, we estimate that γ can be measured with an uncertainty of 15%. We generalize the formalism to account for a range of chirp masses and the possibility that the signal falls as (-R/R 0)/R γ. All Science Journal Classification (ASJC) codes Physics and Astronomy (miscellaneous) Keywords gravitational radiation gravity waves signal-to-noise ratio", "pred_label": "__label__POS", "pred_score_pos": 0.5823335647583008}
{"content": "Researchers described a new strategy of designing metamolecules that incorporates two independently controllable subwavelength meta-atoms. This two-parametric control of the metamolecule secures the complete control of both amplitude and the phase of light.\nA KAIST research team in collaboration with the University of Wisconsin-Madison theoretically suggested a graphene-based active metasurface capable of independent amplitude and phase control of mid-infrared light. This research gives a new insight into modulating the mid-infrared wavefront with high resolution by solving the problem of the independent control of light amplitude and phase, which has remained a long-standing challenge. Light modulation technology is essential for developing future optical devices such as holography, high-resolution imaging, and optical communication systems. Liquid crystals and a microelectromechanical system (MEMS) have previously been utilized to modulate light. However, both methods suffer from significantly limited driving speeds and unit pixel sizes larger than the diffraction limit, which consequently prevent their integration into photonic systems. The metasurface platform is considered a strong candidate for the next generation of light modulation technology. Metasurfaces have optical properties that natural materials cannot have, and can overcome the limitations of conventional optical systems, such as forming a high-resolution image beyond the diffraction limit. In particular, the active metasurface is regarded as a technology with a wide range of applications due to its tunable optical characteristics with an electrical signal. However, the previous active metasurfaces suffered from the inevitable correlation between light amplitude control and phase control. This problem is caused by the modulation mechanism of conventional metasurfaces. Conventional metasurfaces have been designed such that a metaatom only has one resonance condition, but a single resonant design inherently lacks the degrees of freedom to independently control the amplitude and phase of light. The research team made a metaunit by combining two independently controllable metaatoms, dramatically improving the modulation range of active metasurfaces. The proposed metasurface can control the amplitude and phase of the mid-infrared light independently with a resolution beyond the diffraction limit, thus allowing complete control of the optical wavefront. The research team theoretically confirmed the performance of the proposed active metasurface and the possibility of wavefront shaping using this design method. Furthermore, they developed an analytical method that can approximate the optical properties of metasurfaces without complex electromagnetic simulations. This analytical platform proposes a more intuitive and comprehensively applicable metasurface design guideline. The proposed technology is expected to enable accurate wavefront shaping with a much higher spatial resolution than existing wavefront shaping technologies, which will be applied to active optical systems such as mid-infrared holography, high-speed beam steering devices that can be applied for LiDAR, and variable focus infrared lenses. Professor Min Seok Jang commented, \"This study showed the independent control amplitude and phase of light, which has been a long-standing quest in light modulator technology. The development of optical devices using complex wavefront control is expected to become more active in the future.\" MS candidate Sangjun Han and Dr. Seyoon Kim of the University of Wisconsin-Madison are the co-first authors of the research, which was published and selected as the front cover of the January 28 edition of ACS Nano titled “Complete complex amplitude modulation with electronically tunable graphene plasmonic metamolecules.”\nThis research was funded by the Samsung Research Funding & Incubation Center for Future Technology.", "pred_label": "__label__POS", "pred_score_pos": 0.9920772910118103}
{"content": "Abstract\nWe undertook a direct mail campaign to urge persons identified as being at risk for hypertension to seek medical advice. Those who received a single mailing displayed a 28% increase in the proportion who subsequently discussed their blood pressure with a physician and a 12% increase in the proportion who had their blood pressure rechecked, while those persons who received six mailings reported an equivalent increase in physician discussions but a smaller increase in rechecking their blood pressure. These results support the use of inexpensive social marketing strategies as follow-up methods for blood pressure screening programs.", "pred_label": "__label__POS", "pred_score_pos": 0.9886989593505859}
{"content": "E’ uscito nella rivista Economia e Politica Industriale, l’articolo:\n(con G. Giovannetti e M. Velucchi) Heterogeneity in managerial strategies and internationalization of firms: the case of Italy\nAbstract:\nThe recent empirical literature on firm performance has highlighted the multidimensional concept of managerial strategies. The paper analyzes the nexus between these strategies and performance based on specific entrepreneurs’ characteristics, corporate strategies, organizational capabilities and firms’ approaches to internationalization. Using a dataset obtained by matching and merging Capitalia, ICE-Reprint and AIDA surveys we investigate the possible non-linear impact of managerial strategies on firm performance in Italy. While the specific entrepreneurs’ characteristics do not seem to have a significant impact on firm performance, the mode of internationalization plays an important role. Important non-linearities arise when we singled out the role of skilled workers and managers in determining a firm’s success in highly competitive markets.", "pred_label": "__label__POS", "pred_score_pos": 0.7265264987945557}
{"content": "Real Estate and Property\nQatar’s construction and real estate industry has witnessed intense growth in recent years. The skyline of Doha’s business district is often described as having been transformed overnight into what is now a panorama of strikingly unique skyscrapers.\nThe construction industry is expected to continue to grow in the coming years, as the country opens up to foreign property investment. Under current legislation, non-Qataris may invest in selected real estate projects, such as the West Bay Lagoon and The Pearl – Qatar. As part of the incentive to attract foreign investment, real estate visas can now be granted to buyers, allowing them to live in the country without sponsorship.\nFor most residents, though, renting remains the living arrangement of choice. Those who wish to rent an apartment, villa or room have a wide selection to choose from in every area of the city. After years of escalation, rental prices have stabilized as new projects mature and vacancy rates increase. The rights and obligations of tenants and landlords are outlined in the rental laws.\nThe Ministry of Municipality and Environment oversees the preparation of all records related to the selling, leasing, waiver and bequeathing of real estate. Some selected records and documents must bear the approval of the Real Estate and Residences Registration Office to be considered valid. Land owners should visit the office before completing their real estate registrations at the Ministry of Justice.", "pred_label": "__label__POS", "pred_score_pos": 0.8608680963516235}
{"content": "Abstract\nAutoimmune optic neuritis is a common early manifestation of multiple sclerosis (MS), yet early therapeutic interventions for MS often have high ocular toxicity associated with increased risks for glaucoma, cataract, or retinopathy. This need to discover better early treatment options prompted our development of a sensitive and reliable means to quantify the broad range of pathologies that potentially develop very early in autoimmune optic neuritis. Tissue microfluorimetry was used to measure seven established markers for human MS pathology in normal and autoimmune optic nerves 13 days after antigen exposure, in a Brown Norway rat model of myelin oligodendrocyte glycoprotein (MOG) peptide (35-55)-induced autoimmune optic neuritis. Optic neuritis rats demonstrated early and significant pathologic changes in five established indices for neuroinflammation, immune infiltration, and demyelination that accurately modeled pathologies characteristic of MS. Two indices of MS-like axon damage advanced significantly within 13 days of antigen exposure. Fluorimetrically measured immunoreactivity (-ir) was significantly decreased for paranodin (PN, the requisite axonal paranodal junction protein) and significantly increased for amyloid precursor protein (APP), indicating loss of paranodal junctions and impaired fast axonal transport, respectively. Measurements showing decreased PN-ir with increased APP-ir quantitatively defined a pattern of early axonal damage in autoimmune optic neuritis.\nKeywords Autoimmune optic neuritis Axon pathology Experimental methods Multiple sclerosis ASJC Scopus subject areas Neuroscience(all)", "pred_label": "__label__POS", "pred_score_pos": 0.5526483058929443}
{"content": "As U.S. companies continue the transition to remote work, possibly for the long term, ERP project teams continue to face significant challenges in management, coordination, communication and collaboration. And organizations that planned to start a much-needed ERP project are wondering whether to proceed or wait until the day – Sometime next year? – when their people can return to the office.\nFortunately, Ultra has 26 years of experience managing remote teams for manufacturing and distribution organizations. In this non-normal, unsettled business environment, companies need this unique expertise to support their ongoing transformation projects and to help their new ERP efforts start strong.\nIs it possible to keep ERP projects moving forward with remote teams? Yes! We do it every day. Watch this short video to know more. Learn how we leverage technology, collaboration and common sense to successfully manage remote teams – and see how we apply these strategies to our client projects. Watch this excerpt from a recent webinar.", "pred_label": "__label__POS", "pred_score_pos": 0.9227161407470703}
{"content": "Dr Leigh Hoath\n'The conundrum we face is ensuring children are taught the science they need to form a literate society, while the science is running away from the\nDr Leigh Hoath\nDr Leigh Hoath\nHolly Bestley from the Zoological Society of London outlines how technology can help make the most of exploring the natural world.\nHolly Bestley\nJen and Steve Smyth highlight how you can support your science teaching trains your next stop announcing the next stop in your classroom!\nJen Smyth\nKate reflects on her school's journey in engaging children in engineering and technology.\nKate Sutton\nLiz highlights the importance of meeting all the demands of teaching design and technology when it is often taught alongside science.\nLiz Lawrence\nWhat does effective ‘Environmental’ or ‘Sustainability Education’ look like? How does this link to best practice STEM education?\nMargaret Fleming\nSustainability and sustainability education, written by a range of experts in the field, education practitioners and environmental organisations.\nMargaret Fleming et al\nPaul considers ways of teaching about ecosystems that challenge doing things 'the way we have always done them'.\nPaul Tyler\nOpen-ended investigations, supported by class discussion, can lead to a deep exploration of a topic.\nRobert M. Ritchie\nRory describes how everyday technology is used in his role as an agronomist.\nRory Galloway", "pred_label": "__label__POS", "pred_score_pos": 0.9102515578269958}
{"content": "Rod wipers scrape dirt, dust, and moisture from the rod, preventing contamination inside your cylinder.\nRod seals maintain the pressure inside cylinders and prevent fluid from leaking out.\nWear rings guide the rod and piston to prevent uneven wear and optimize seal performance.\nHead seals are a more reliable alternative to the standard O-ring/backup ring combination—they resist twisting and remain stable even in applications with fluctuating pressure.\nBuffering seals protect hydraulic cylinders from pressure spikes and shock in high-pressure hydraulic applications.\nCushioning seals minimize wear and noise in air-powered cylinders by preventing the piston from slamming against the cylinder body.\nPiston seals make a seal between their outside edge and the cylinder bore to prevent internal leaks.", "pred_label": "__label__POS", "pred_score_pos": 0.9977577924728394}
{"content": "\"Whoever dwells in the shelter of the Most High will rest in the shadow of the Almighty\" (Psalm 91:1, NIV). Gales whirl in a violent uproar outside my office window. Hail batters the roof like a viral-shaped threat to any who would dare brave the outside world. The tears of…\nFrom pandemic health and loss struggles to violence and division, the 2020 year has pummeled us. We face an aftermath of financial struggles, family strain, and despair. Even those who once felt confident may now wonder if we can ever restore our lives. Is there hope for recovery after so…\nDiets garner immense popularity at the start of the new year and make a resurgence in the months prior to swimsuit season. Some fads encourage us to eliminate food groups or restrict calories. Other experts insist we can indulge in a specific type of food while avoiding everything else. The stricter…\nSome face relationship issues while others suffer from loneliness. From disappointments to frustration or even anger, this week's circumstances could rattle your heart. In fact, any given time of year can present us with a torrent of emotions. We can rise on a wave of happiness with high expectations and…\nWelcome to the month of hopeless romanticism and hapless heartbreak. The retail world blushes all shades of pink, red, and lavender in an urge to sell us passion in packages. Singles resent the reminders of their isolation. Couples stress over how to avoid disappointing their beloved ones. Moms sigh over…\nJanuary has three weeks bulging under her belt. Many of this month's early-date fans now resent her as much as their own waistlines. Unlike the fickle masses, statistics maintain a consistent view of January. She reflects human nature's tendency to launch with the boldest of aspirations only to crash into…\nOur last discussion offered the overview of our whole-person makeover series to launch your new year with habits you can sustain forever. We noted the importance of taking small, maintainable steps toward the lifestyle which blesses the rest of your days. The significance of addressing all areas of our well being…\nChristmas arrives in less than a week. In homes where we've been intense pain, our childlike hearts look forward to shared joys and enchanting moments we will remember in coming years. We also prepare to exchange gifts with those we love. For some, the sorrows of loss and suffering darken…\n\"But you are a chosen people, a royal priesthood, a holy nation, God’s special possession, that you may declare the praises of him who called you out of darkness into his wonderful light\" (1 Peter 2:9). Who doesn't love the scents of this season? From balsam fir to peppermint, I…\nEver contemplate the gifts of Christ when you admire a creche? Nativity scenes often imply three wise men visited the newborn Savior on the first Christmas. Scholars believe the visit might have occurred a bit later than the night of Jesus' birth and no specific number of magi are mentioned in…", "pred_label": "__label__POS", "pred_score_pos": 0.5937273502349854}
{"content": "Key Elements of the CARES Act\nCongress recently passed the Coronavirus Aid, Relief and Economic Security (CARES) Act to support businesses and individuals during the current crisis. Several of its provisions might benefit you or someone you know.\nRecovery Rebate\nThe feature attracting the most headlines is the “Recovery Rebate” program under which individuals are entitled to receive up to a $1,200 refundable tax credit and married couples receive up to $2,400. Those with children under age 17 can receive an additional $500 for each child. The credit phases out depending on your aggregate gross income (AGI) on your 2019 taxes (or 2018 if you have not yet filed your 2019 return). The Tax Foundation has an excellent guide to the rebate program and a calculator that can help determine how much you will receive.\nNo RMDs for 2020\nUnder the CARES Act, individuals with Required Minimum Distributions (RMDs) for their own retirement accounts or those they have inherited are no longer required for 2020. This will provide a tax savings for those who will usually have to take RMDs and do not need the distributions for ongoing spending. Those who have already taken RMDs from their own retirement accounts in 2020 have the option of returning them to their account.\nEnhanced Unemployment Benefits\nThe CARES Act extended unemployment benefits for an additional 13 weeks after standard state benefits end. The legislation also increased regular unemployment compensation by $600 per week through July 31. Self-employed workers and independent contractors are now eligible for unemployment and the one-week waiting period for benefits has been waived for all applicants.\nDeferred Student Loan Payments\nThe CARES Act suspended required payments on federal student loans through September 30, 2020 and interest will not accrue on the loan during this time. Borrowers will need to stop any automatic payments for their federal student loans to take advantage of this provision. This time period also will continue to count for loan forgiveness programs, such as the Public Service Loan Forgiveness program.\nExtended Federal Tax Filing and IRA Contribution Deadlines\nOutside of the CARES Act, the IRS extended the deadline to file 2019 federal tax returns to July 15. This also means that contributions to IRAs for 2019 can also be made until July 15.\nThese are only some of the features of the government’s Coronavirus response, which also includes wide-ranging benefits for businesses. Here is the Tax Foundation’s detailed breakdown of the full CARES Act.", "pred_label": "__label__POS", "pred_score_pos": 0.6957868337631226}
{"content": "One of the recurring themes throughout the year has been growth. As I mentioned, I lived the typical, busy college student schedule before entering the service term. Once I started serving at my host site, I realized that this was no longer needed to feel “accomplished” or “busy”. Sometimes a complicated fifteen-minute encounter trying to help a patient who is uninsured, speaks a different language than me, and has just heard a life altering diagnosis of diabetes is enough to exhaust someone. There was not a textbook or syllabus to guide in these interactions, so I quickly had to grow and be confident I could do my part efficiently and correctly.", "pred_label": "__label__POS", "pred_score_pos": 0.6270713806152344}
{"content": "Your business’ technology is extremely important to your business’ success and ensuring that it is functioning as designed has to be an ongoing priority. This can be harder than you may think. Today, we’ll go over how you can actively confront this challenge and keep your IT running as it should.", "pred_label": "__label__POS", "pred_score_pos": 0.9989794492721558}
{"content": "What Healthcare Organizations should know about the GDPR Data protection regulations define how an individual's personal information can be used by organizations, businesses and government. These regulations also contain safeguards that seek to ensure healthcare data is not susceptible to attack, misuse or misappropriation. As most know, misusing an individual's healthcare data or not properly following regulation guidelines can hold especially serious long-term consequences. This spring, the GDPR was adopted with the aim of having one set of rules applicable throughout the European Union (EU). This has significant implications not only for EU-based organizations, but also for non-EU based organizations that conduct business or business communications in EU countries. The GDPR further aims to ensure privacy by design or default, meaning that data protection measures must be implemented across all data processing activities and endpoints. These changes are not revolutionary; the key principles, concepts and themes of the current data protection system remain. The new rules build on what is already in place with the addition of several new requirements. The Healthcare industry is facing multiple challenges when it comes to protecting sensitive data. This paper provides an overview of how the recent EU General Data Protection Regulations will affect healthcare organizations.", "pred_label": "__label__POS", "pred_score_pos": 0.9088643789291382}
{"content": "Four hui have been held with iwi chief executives to help them access the Tai Tokerau regional decision-support tools being developed by the Mauri Whenua Ora research team, led by Dr Merata Kawharu with hui held by Garth Harmsworth (Te Arawa, Ngati Tuwharetoa, Ngati Raukawa).\nChief Executive input to the design of these tools and a gap analysis of Tai Tokerau economic development reports are important for ensuring that these tools effectively support hapū and iwi in achieving their land innovation goals.\nThe hui and gap analysis identified that:\nThere is interest in tools and models that can support iwi/Māori landowner decision-making, though these tools need to be tailored to iwi issues/aspirations Tools must support the complexity of iwi decision-making across social, environmental, economic-development, political and cultural goals While access to data relevant to answering iwi issues/aspirations is important to support decision-making, these data must be presented in a way that makes them meaningful, useful, and accessible to iwi and Māori landowners\nGIS is of interest, but the value of GIS to iwi is dependent on their capacity to use GIS tools, the costs to set up the software, access it, and train iwi members in its use.\nThis work was funded by Our Land and Water to develop methods for co-designing iwi-relevant decision-support tools and the decision-support tools themselves, which will then be available to other groups developing such tools for iwi and hapū.\nThese decision support tools will ultimately help enable iwi and hapū to explore innovative land uses to realise their social, environmental, economic-development, political and cultural aspirations.\nMāori play a significant role in New Zealand’s primary sector economy, including the pastoral, horticultural, cropping and forest industries. The asset base of Māori enterprises in 2010 was at least $36.9 billion. Māori enterprises in agriculture alone carry 10-15% of national sheep and beef stock units, provide 8-10% of the national milk solids, and contributed about $0.7 billion to the NZ economy in 2010.\nIdentifying and addressing barriers to innovative land uses by Māori will increase the impact in these sectors for both Māori and non-Māori, ultimately making a significant contribution to New Zealand economic, environmental, social and cultural outcomes.\nEarly uptake is evidenced by Tony Dowling (CEO Te Runanga o Ngapuhi) working with the Mauri Whenua Ora programme to bring together a small team to contribute to further gap analysis, with respect to information central to Ngapuhi development. Extension of the work to the Bay of Plenty icurrently underway will provide learnings for its national application.\n—\nFor more on this research project, see Mauri Whenua Ora", "pred_label": "__label__POS", "pred_score_pos": 0.7734915018081665}
{"content": "We aim to determine the efficacy and safety of gene and cell angiogenic therapies in the treatment of peripheral arterial disease (PAD) and evaluate them for the first time by a meta-analysis. We include in the formal meta-analysis only the randomized placebo-controlled phase 2 studies with any angiogenic gene or cell therapy modality to treat patients with PAD (intermittent claudication, ulcer or critical ischemia) identified by electronic search in MEDLINE and EMBASE databases (1980 to date). Altogether, 543 patients are analyzed from six randomized, controlled trials that are comparable with regard to patient selection, study design, and endpoints. We perform the meta-analysis regarding clinical improvement (improvement of peak walk time, relief in rest pain, ulcer healing or limb salvage) and rate of adverse events. At the end of treatment, therapeutic angiogenesis shows a significantly clinical improvement as compared to placebo in patients with PAD (odds ratio [OR] = 1.437; 95% confidence interval [CI] = 1.03-2.00; P = 0.033). The response rate (improvement of peak walk time) of the pooled groups according to clinical severity does not significantly differ for gene therapy as compared with placebo in the treatment of claudicating patients (OR = 1.304; 95% CI = 0.90-1.89; P = 0.16). Otherwise, we find significant efficacy of the treatment in critical ischemia (OR = 2.20; 95% CI = 1.01-4.79; P = 0.046). The adverse events rates show a slightly significantly higher risk of potential nonserious adverse events (edema, hypotension, proteinuria) in the treated group (OR = 1.81; 95% CI = 1.01-3.38; P = 0.045). We find no differences in mortality from any cause, malignancy, or retinopathy. The patients with PAD, and particularly those with critical ischemia, improve their symptoms when treated with angiogenic gene and cell therapy with acceptable tolerability.", "pred_label": "__label__POS", "pred_score_pos": 0.5518442988395691}
{"content": "Pattaya-\nPattaya City officials have stated that Pattaya City Public Schools, closed for roughly four months due to Covid-19, are finally set to re-open but that things will look very different under strict rules and regulations set into effect to help prevent the potential spread of Covid-19.\nAmong other measures, some of the rules and measures being taken are as follows:\n1. Having screening measures, such as temperature checks and hand sanitizer stations before entering the school. Parents will not be allowed to enter the school area and pick-up and drop-off areas will be tightly controlled.\n2. All staff and children must wear a face mask at all times when in school. Young children who find masks uncomfortable can wear a face shield instead.\n3. Adequate hand washing with alcohol, gel, soap between every classroom with stations set up around the school.\n4. Students will be in the same group for all classes-IE, they will go teacher to teacher with the same class and not have different students in each class.\n5. High focus on sanitizing all surfaces of the school at all times, such as doorknobs and rails.\n6. Reduce congestion, do not organize activities that result in the integration of children from different groups. At the start of the school season, there will be a limit/lack of sports, events that bring people together. As the situation is shown to hopefully not cause a spread of Covid-19 these rules will be relaxed.\n7. 1.5 meter spacing between all desks.\n8. All desks must have barriers around them.\n9. Staggered lunch time schedules, students may not sit next to each other at lunch and must be separated 1.5 meters apart from each other.\n10. Alternative scheduling for some students with alternating days of learning to avoid being exposed to a larger group of people.\n11. Crosswalks being strictly manned and encouraging social distancing.\n12. School staff devoted to ensuring students socially distance and do not gather, play and socialize in hallways or public spaces of the schools.\nCritics on social media have expressed concern that the measures, which are stricter than nearly any business venue, will hurt the social development of children and are not needed based on the official recorded and confirmed number of cases of Covid-19 in Pattaya and Thailand. Pattaya has not recorded a single confirmed case of Covid-19 in 73 days.\nHowever, the Ministry of Education has stressed that many parents remain concerned and were hesitant to send their children to school without the enhanced and strict rules and regulations. They stated that if the school re-opening did not show an emergence of the virus and new cases that rules would be gradually eased and relaxed to encourage social development of children and allow more activities.", "pred_label": "__label__POS", "pred_score_pos": 0.6826779842376709}
{"content": "The German Federal Network Agency has announced PV feed-in tariffs (FiTs) will suffer a monthly 1.8% degression, effective today and then on 1 June and 1 July.\nThe FiT is calculated depending on the number of installations from the previous quarter, which experienced a shortfall. Therefore this represents a slower degression when compared with the previous three months of 2.2%.\nJochen Homann, president of the Federal Network Agency, said that although PV systems installed in March exceeded the 2,500-3,000MW allocated for each year, the excess was not as significant as previous months, thereby negating a need for a steeper degression rate. By default, FiTs are reduced by 1% each month.\nFor March, the Federal Network Agency registered 290.5MW of installed capacity which qualified for the FiT.\nMarket research firm EuPD has forecast a significant reduction in new PV capacity in Germany in 2013 expecting only 3.9GW compared to 7.6GW installed in 2012.\nThe new FiT degression rate means systems up to 10kW will receive €0.1563 (US$20.433) per kWh starting 1 May.\nFrom 1 June, the tariff will be reduced to €0.1535 per kWh, and on 1 July, the tariff will fall to €0.1507 per kWh. Larger systems up to 40kW will receive €0.1483, €0.1456 and €0.1430, respectively, while plants up to 1 MW will receive €0.1323, €0.1299 and €0.1275, respectively.\nFinally, PV plants from 1 to 10MW in size will receive €0.1082, €0.1063 and €0.1044 in May, June and July, respectively.\nThe Federal Network Agency will announce the new tariff degression rate for the quarter starting 1 August in late July.", "pred_label": "__label__POS", "pred_score_pos": 0.5786569118499756}
{"content": "Dziobczenski, P.R.N., Person, O. & Meriläinein, S. (2018). Designing Career Paths in Graphic Design: A Document Analysis of Job Advertisements for Graphic Design Positions in Finland.\nThe Design Journal, 21 (3), 349-370. Abstract\nHow to practically monitor what is sought from designers in practice forms a basic concern for educators in design. In this paper, we analyse what employers require from applicants in 230 job advertisements for graphic design positions from Finland. We structure the requests stated in the advertisements in terms of what graphic designers are expected (a) to deliver, (b) to know, and (c) to have. We compare the specific requirements listed for traditional and digital graphic design positions. The results of our analysis suggest that the skill set outlined in the advertisements for traditional graphic design positions suggests a more ‘generalist’ professional, whereas the skill set outlined for digital positions suggests a more ‘specialist’ professional. We end the paper by discussing the implications of our findings for graphic design education and how our research process could inform educational programme developments.", "pred_label": "__label__POS", "pred_score_pos": 0.9327121376991272}
{"content": "The Digest’s 2016 8-Slide Guide to NREL’s High-Octane Mid-Level Ethanol Blend Market Assessment\nby Jim Lane (Biofuels Digest) This past month, NREL published a critical assessment on the viability of High-Octane Mid-Level Ethanol Blends and the impact on US energy options. The complete assessment is here.\nNREL writes:\nThe introduction of more stringent standards for fuel economy and GHG tailpipe emissions is driving research to increase the efficiency of spark ignition (SI) engines. Advanced strategies for increasing SI engine efficiency are enabled by higher octane number (more highly knock-resistant) fuels. Ethanol has a research octane number (RON) of 109, compared to typical U.S. regular gasoline at 91–93. Accordingly, high RON ethanol blends containing 20 vol% to 40 vol% ethanol are being extensively studied as fuels that enable design of more efficient engines. These blends are referred to as high-octane fuel. HOF could enable dramatic growth in the U.S. ethanol industry, with consequent energy security and GHG emission benefits, while also supporting introduction of more efficient vehicles. HOF could provide the additional ethanol demand necessary for more widespread deployment of cellulosic ethanol. However, the potential of HOF can be realized only if it is adopted by the motor fuel marketplace. This study assesses the feasibility, economics, and logistics of this adoption by the four required participants—drivers, vehicle manufacturers, fuel retailers, and fuel producers. It first assesses the benefits that could motivate these participants to adopt HOF. Then it focuses on the drawbacks and barriers that these participants could face when adopting HOF and proposes strategies—including incentives and policies—to curtail these barriers. These curtailment strategies are grouped into scenarios that are then modeled to investigate their feasibility and explore the dynamics involved in HOF deployment. This report does not advocate for or against incentives or policies, but presents simulations of their effects. READ MORE and MORE (Advanced Biofuels USA)\nExcerpt from Advanced Biofuels USA: During a conversation after his speech, (US Department of Energy Secretary Dr. Ernest) Moniz recognized the major research on biofuels at DOE research centers at Oak Ridge, Berkeley and Great Lakes (Michgan State and University of Wisconsin). In particular, he mentioned researchers identifying E30 as a “sweet spot” for higher ethanol concentrations. READ MORE", "pred_label": "__label__POS", "pred_score_pos": 0.7231224775314331}
{"content": "Since the publication of her 2007 monograph Epistemic Injustice, Miranda Fricker’s conceptual framework of epistemic injustice has been widely discussed across disciplines as a useful lens through which we can explore how humans relate to one another as both knowers and seekers of knowledge. It has not, however, yet been widely discussed within the context of libraries and librarianship. Given the growing conversation in our field surrounding librarians’ role in communicating the importance of truth and the potential pitfalls of unchecked or unacknowledged bias, this is an important moment for librarians and information professionals to interrogate how we communicate about “facts” and the potential biases within our practice which may be supporting structural inequity.\nIn an era of intensive focus on equipping citizens, students in particular, with the intellectual tools necessary to detect fallacies masquerading as truth, it is equally important to reflect on what we as information professionals and educators are espousing when discussing who or what students can trust. What roles do testimony and lived experience have in our classrooms, research, and lives? Instruction which begins and ends with scholarly publishing neither adequately prepares students for the epistemic landscape they face, nor addresses the narrow perspectives which have been and continue to be privileged in scholarly conversations. By mapping Fricker’s notion of epistemic injustice on to ILI I hope to present a novel lens with which instruction librarians can consider how they address issues of authority both in their curriculum and pedagogy.", "pred_label": "__label__POS", "pred_score_pos": 0.6419805884361267}
{"content": "Therapy Areas Non-dystrophic Myotonias\nMyotonic disorders are a group of rare, heterogeneous, inherited, neuromuscular disorders characterized by a shared symptom called myotonia. Myotonia can be described as an inability to relax a contraction of skeletal muscle which originates from a voluntary muscular contraction such as shaking someone’s hand and blinking, or everyday activities such as walking across a street and climbing stairs.\nNon-dystrophic myotonias (NDM) are a sub-set of rare (prevalence of 1:100,000\n1 ), inherited, myotonic disorders which are caused by mutations within ion channels in the sarcolemma membrane of skeletal muscles. Non-dystrophic myotonias exhibit both sodium and chloride channelopathies, resulting in altered membrane excitability. For patients with NDM, myotonia is the most prominent symptom and demonstrates different phenotypes in subgroups of NDM disorders, and can affect different parts of the body, such as legs, arms or facial muscles, more severely.\nMyotonia symptoms in NDM patients has an onset in childhood, which is often perceived by patients to persist, and even increase in severity, over their lifetime, impacting daily life\n2,3. Myotonia is described by patients in a variety of ways, and is often referred to as stiffness, cramps, pain, difficulty releasing a fist, or difficulty swallowing or eating. This can contribute to substantial delays in diagnosis and treatment, leading to decreased patient quality-of-life and often significant disability. Reference:1. Emery AE, et al. Neuromuscular Disorders 19912. Trivedi JR, et al. Exp Neurol 20143. Trip J, et al. J Neurol 2009", "pred_label": "__label__POS", "pred_score_pos": 0.9941793084144592}
{"content": "Balancer chromosomes are genetic reagents that are used in Drosophila melanogaster for stock maintenance and mutagenesis screens. Despite their utility, balancer chromosomes are rarely used in mice because they are difficult to generate using conventional methods. Here we describe the engineering of a mouse balancer chromosome with the Cre-loxP recombination system. The chromosome features a 24-centiMorgan (cM) inversion between Trp53 (also known as p53) and Wnt3 on mouse chromosome 11 that is recessive lethal and dominantly marked with a K14-Agouti transgene. When allelic to a wild-type chromosome, the inversion suppresses crossing over in the inversion interval, accompanied by elevated recombination in the flanking regions. The inversion functions as a balancer chromosome because it can be used to maintain a lethal mutation in the inversion interval as a self-sustaining trans-heterozygous stock. This strategy can be used to generate similar genetic reagents throughout the mouse genome. Engineering of visibly marked inversions and deficiencies is an important step toward functional analyses of the mouse genome and will facilitate large-scale mutagenesis programs.", "pred_label": "__label__POS", "pred_score_pos": 0.7609013915061951}
{"content": "J Int Soc Sports Nutr 13:1-015-0112-9, 2016 describe the efficacy of branched chain amino acid (BCAA) supplementation and resistance training for maintaining lean body mass during a calorie-restricted diet, and claim that this occurs with concurrent losses in fat mass. However, the reported results appear to be at odds with the data presented on changes in fat mass. This letter discusses the issues with the paper.", "pred_label": "__label__POS", "pred_score_pos": 0.9952460527420044}
{"content": "Abstract\nThe discovery that immunotherapy is a clinically-relevant approach for the treatment of malignant tumors is brain tumor, autologous HSPPC-96 vaccination provides a significant increase in overall survival. However, all GBM patients eventually succumb to their disease, providing rationale for discovering new methods that proactively identify individuals that will respond, optimally. Of the immunosuppressive mediators that contribute to the inhibition of productive tumor immunity, indoleamine 2, 3 dioxygenase 1 (IDO1), a rate-limiting enzyme that catabolizes tryptophan (Trp) into kynurenine (Kyn), has been demonstrated to be expressed at elevated levels in patients with malignant glioma. Recently, our group determined that a correlation exists between peripheral blood Trp and Kyn levels in GBM patients and the association with overall survival after HSPPC-96 treatment. Our findings indicate that the Kyn/Trp ratio may be a useful benchmark for identifying GBM patients with a higher likelihood to survive longer after vaccination. The relevance to future clinical trials, the limitations of brain tumor models to address these findings and the role of IDO1 versus tryptophan dioxygenase (TDO) in the maintenance of peripheral Trp and Kyn levels, is discussed.\nKeywords Glioma IDO Immunosuppression Immunotherapy T cell Treg ASJC Scopus subject areas Immunology and Allergy Immunology Oncology", "pred_label": "__label__POS", "pred_score_pos": 0.9788177609443665}
{"content": "Cardiac Rhythm Monitoring An Overview\nHeart rhythm monitoring is recommended when patients are exhibiting symptoms of heart rhythm disturbances such as arrhythmia, atrial fibrillation, palpitations, and dizziness. Buckeye Heart & Vascular Institute offers a full range of diagnostic testing to help identify various arrhythmias and abnormal heart rhythm problems.\nWhat are the most common abnormal heart rhythms?\nThe most common abnormal heart rhythms include: Tachycardia, Atrial fibrillation (AF), Atrial flutter, Bradycardia, and Premature contractions (PAC). Abnormal heart rhythms can be fast, slow, or irregular. The type of treatment you receive for a heart arrhythmia will depend on the kind of abnormal beat.\nCan you shower with a cardiac event monitor?\nWe do not recommend showering with a cardiac event monitor as water can damage the device and interfere with results. A a cardiac event monitor can be removed and reattached for personal hygiene reasons.\nCan you drink coffee while wearing a Holter monitor?\nWe ask that you limit your coffee intake as well as alcohol consumption as these can cause heart rhythms not associated with heart problems and report inaccurate results.\nCardiac Rhythm Monitoring What to Expect Electrocardiogram (EKG)\nEKG, also known as an electrocardiogram, is a test that measures the electrical activity of your heart at rest.\nAn EKG measures your heart’s electrical activity. During an EKG, your technician will place small electrode patches on the chest, legs, and arms. These electrodes are connected to a machine that will produce a detailed report on the hearts rate and rhythm.\nAn EKG is a quick, non-invasive test that allows your doctor to identify any abnormalities in the heart rhythm or rate, diagnose a heart attack, measure the size of the heart and analyze blood flow to the heart. An EKG is typically performed in one visit and only takes a few minutes for the computer to analyze the electrical impulses. Once completed, your physician will interpret the reading and determine if further testing or treatment is needed.\nHolter Monitor\nA Holter monitor is a small device that records your heart rhythm. A Holter monitor may be worn for 24 hours up to a week. The Holter monitor is attached to the chest using EKG electrodes and wires. The portable device is then secured to the belt loop, allowing patients to resume their normal activity after the appointment. It is imperative that patients do not get their device damp or wet because it can interfere with the results.\nWhile in use, the Holter monitor records all of the heartbeats. The recordings are converted to the similar readings an EKG may provide. You may be asked to keep a diary of your symptoms while wearing the Holter monitor. With the information gathered from the Holter monitor, your physician can determine if you have a heart rhythm disorder.\nCardiac Event Monitor\nCardiac arrhythmias may occur sporadically, occurring every few days, weeks, or months. Cardiac event monitors allow patients to record their symptoms as they experience their symptoms. Patients will activate the EKG device which will record the heart rhythm at the time of activation. Patients are encouraged to keep an activity and symptom journal throughout this process.\nA cardiac event monitor is a small, portable device that records your heart’s electrical activity. A cardiac event monitor records the heart rate and rhythm while a patient is experiencing a cardiac “event.” The monitor may be worn for several days or up to a month. Patients can remove their cardiac event monitor to perform their hygiene routine but will need to reattach it afterward. Your physician will explain how to use the device during your appointment.\nYour physician will receive daily reports from the cardiac event monitor. Once treatment is completed, your physician will determine if any additional testing or treatment is needed.", "pred_label": "__label__POS", "pred_score_pos": 0.5654295682907104}
{"content": "Can You Sue a New Jersey Nursing Home for COVID-19 Infection or Wrongful Death?\nCoronavirus continues to spread in nursing homes across New Jersey at an alarming rate, and NJ is not alone. According to\nUSA Today, at least 2,300 long-term care facilities across 37 states have reported positive cases of coronavirus. However, the figure could be much higher because many state agencies did not provide data. At least 3,000 residents have died in those facilities.\nBut can nursing home residents – or their family members, for that matter – sue the facility for COVID-19 exposure?\nPolice Discover 17 Bodies Piled Up in a New Jersey Nursing Home\nA disturbing report came from\nThe New York Times on April 15. The police in Andover, a small New Jersey town, received an anonymous tip about a body lying in a shed outside Andover Subacute and Rehabilitation Center, one of the state’s largest nursing homes.\nWhen the police arrived, the body had been removed from the shed, but officers discovered 17 bodies piled inside the facility in a small morgue that was only intended to hold four bodies. Those were 17 among 68 recent deaths linked to the nursing home. Of those who died, 26 had tested positive for COVID-19. The cause of death for others remains unknown.\nMeanwhile, 76 patients who remain at the nursing home, housed in two buildings, have tested positive for COVID-19. Also, 41 workers contracted coronavirus.\nThe news comes as the number of New Jersey’s nursing homes where residents were diagnosed with coronavirus “more than doubled” in just a week, according to\nNorthJersey.com. The number skyrocketed to 285, which is more than three-quarters of the state’s total number of nursing homes.\nAt least 252 residents of these facilities have died. These deaths account for one in eight of New Jersey’s total death toll from coronavirus.\nCan a New Jersey Nursing Home Be Sued for COVID-19?\nIn light of these disturbing reports, many family members of nursing homes residents in New Jersey are wondering whether they can sue the facility for exposing their relative to coronavirus or causing wrongful death.\nWhen suing a nursing home – or filing any personal injury claim – the plaintiff is required to prove that the nursing home failed to take “reasonable steps” to prevent the COVID-19 exposure or outbreak within the facility. In response to the pandemic, the Centers for Disease Control and Prevention issued special guidelines for nursing homes to minimize the risk of COVID-19 outbreaks among senior citizens, the most vulnerable group of people.\nUnfortunately, despite the older population being at higher risk for serious illness from coronavirus, many nursing homes fail to take reasonable measures to prevent the spread of the virus. But do family members of residents or residents themselves have any legal recourse against negligent facilities?\nTheoretically speaking, yes, they do. However, much depends on whether you have sufficient evidence to prove that the nursing home failed to take reasonable measures to prevent the outbreak. Speak with a Morristown personal injury attorney to determine whether you have a valid claim against the nursing home to sue for COVID-19 exposure. Our lawyers at Law Offices of Michael P. Burakoff, P.A., can help evaluate your case. Call at 973-455-1567.\nResources:\nnorthjersey.com/story/news/coronavirus/2020/04/11/nj-nursing-home-crisis-deepens-deaths-coronavirus-increase/5134089002/\nnytimes.com/2020/04/15/nyregion/coronavirus-nj-andover-nursing-home-deaths.html\nusatoday.com/story/news/2020/04/13/coronavirus-nursing-homes-2-300-facilities-report-positive-cases/2978662001/", "pred_label": "__label__POS", "pred_score_pos": 0.6647846102714539}
{"content": "Hexa ReportsMarket Research Reports and Insightful Company Profiles\nGlobal Self-Monitoring of Blood Glucose Market Data,Global Insights, Share, Size, Emerging Trends, Growth,Analysis & Forecasts To 2025\n‘The Global Self-Monitoring of Blood Glucose Market to 2025’ is GMR Data’s latest pharma report,covering the pharmaceutical, commercial and strategic developments in the global Self-Monitoring ofBlood Glucose (SMBG) market. The report highlights key companies, geographies and products that webelieve will deliver strong growth across the next decade.SMBG is now globally recognised as an integral part of intensive therapy for diabetes; SMBG providesincreasingly accurate blood glucose readings which offers significant benefits to diabetics and ultimately,financially, their healthcare providers.Browse Detail Report With TOC @http://www.hexareports.com/report/the-global-self-monitoring-of-blood-glucose-market/detailsThe SMBG market is primarily driven by the growing global diabetic population; a lack of a cure fordiabetes; increasing health education among the diabetic population, active reimbursement policies ofinsurers; the technological advancement aimed at minimal and non-invasive blood glucose testingmethods, alongside the availability of blood glucose meters at a nominal cost.The market for SMBG products has a future simply because of the growing incidence and prevalence ofdiabetes, increasing spending on healthcare and growing awareness and its implications. However, key\nHexa ReportsMarket Research Reports and Insightful Company Profileschallenges remain such as data accuracy, affordability and reimbursement which need to be addressedby the manufacturers, insurance companies and national health authorities.‘The Global Self-Monitoring of Blood Glucose Market to 2025’ report includes over 200 tables, chartsand graphs quantifying and forecasting the market in detail. In addition, the report offers 9 profiles ofthe leading companies in the...", "pred_label": "__label__POS", "pred_score_pos": 0.9093360900878906}
{"content": "Question\nIf a FAR such as 52.291-9 Small business Plan is specified in the Government's Request for Proposals (RFPs) but the DoD suplement is not specified in the RFP, does the supplement apply?\nAnswer\nThis question deals with FAR Subpart 15.2 – Solicitation and Receipt of Proposals and Information. FAR 15.201(a) lays the foundation principle that contracting officers are encouraged to promote early and open communication amongst all interested parties. With this principle in mind, FAR 15.201(b) through (e) provides detailed suggestions further supporting the intent to foster maximum understanding through communication. FAR 15.201(f) emphasizes the contracting officer as the focal point of any exchange with potential offerors after release of the solicitation. According to the scenario presented in this question, the solicitation is a request for proposals (RFP). Thus, potential offerors should contact the contracting officer or, their designated representative as indicated in the RFP, with any and all questions seeking clarification of the government’s requirement in this instance.\nOpen full Question Details", "pred_label": "__label__POS", "pred_score_pos": 0.990075409412384}
{"content": "Why Sit when you have the option of Moving???? My Personal Fitness Program I was ignorant of the importance and how 84% of my behavior dictated my current illnesses that I suffer with as a 63 year young female. I never realized the damage of a sedentary lifestyle until I was diagnosed with sciatica a few years ago. Sitting for long periods while doing homework and before that, I had jobs in the past that I sat for hours on the phone. Somewhat ironic that I worked for a hospital, and their mission statement stated \"preventative care\" as part of their selling point. Unfortunately, there were no programs in place to ensure that the staff was trained in preventive care to prevent lower back issues. Not to mention the additional illnesses that plague a person from sitting too long. The majority of people that I worked with are probably suffering from similar problems to this day. In the United States, physical inactivity is the second most significant threat to public health and is often referred to in new concerns about \"Sitting Disease\" and \"Sedentary Death Syndrome\" or SeDs, (Hoeger, Hoeger, Hoeger, & Fawson, 2017, p. 3). In the past, I danced as a form of exercise. However, I stopped and never joined a gym or fitness center. The factors that have kept me from exercising in the past, \"I'm too busy,\" \"I don't enjoy working out,\" and \"I'm in shape already.\" To the contrary, it is not about being shapely. However, it is about being in shape. I met with my medical doctor , and I am scheduled to start a weight management program through my doctor's office to gain a jump start. Furthermore, I realize a critical component is that God created our bodies to be mobile as we serve Him in the kingdom.\nYou must start an exercise regiment as soon as possible. It's too late on your death bed to start the conversation, what I should have done, it's too late at that time. You can do this!!!", "pred_label": "__label__POS", "pred_score_pos": 0.8165726661682129}
{"content": "While lifting in general will lead to hypertrophy, recent studies have shown that lifting higher reps 10+ can lead to hypertrophy without necessarily strength because the endurance required more water to be retained in the muscles resulting in a larger appearance. Lifting within 3-6 reps drastically increases strength without necessarily muscle size.While the muscle fibers will grow, its the increase in water retention that really expands the muscles.\nADVERTISEMENT", "pred_label": "__label__POS", "pred_score_pos": 0.9966148734092712}
{"content": "Whether your organization’s Executive Director was promoted from within or hired from outside the organization, Basic Training can prepare him/her for successful leadership.\nThis key role is responsible for a wide range of accountabilities. Being effective at all of them requires preparation and commitment to excellence.\nImportant areas of preparation include leading the staff, partnering with the board of directors, working with staff and board to develop and execute a fundraising plan, being an ambassador for your mission, ensuring your nonprofit is fiscally sound, identifying potential risks, engaging in strategic planning, building relationships with donors and other supporters, managing volunteers, and marketing to your community.\nContact Nonprofit Kinect today for a free consultation on how your organization can ensure top-notch training for your Executive Director.", "pred_label": "__label__POS", "pred_score_pos": 0.9281562566757202}
{"content": "School transport is a significant operation managed by Bus Éireann on behalf of the Department.\nThe purpose of my Department's School Transport Scheme is, having regard to available resources, to support the transport to and from school of children who reside remote from their nearest school.\nIn the 2018/2019 school year over 117,500 children, including over 13,000 children with special educational needs, were transported in over 5,000 vehicles on a daily basis to primary and post-primary schools throughout the country covering over 100 million kilometres at a cost of over €200m in 2018.\nUnder the terms of the Primary School Transport Scheme, children are eligible for transport where they reside not less than 3.2 kms from and are attending their nearest national school as determined by the Department/Bus Éireann, having regard to ethos and language.\nA minimum number of 10 eligible children residing in a distinct locality, as determined by Bus Éireann, are required before consideration may be given to the establishment or retention of school transport services, provided this can be done within reasonable cost limits.\nFamilies who wish to avail of school transport and have their eligibility status assessed should apply on-line in a timely manner to Bus Éireann\non Bus Éireann’s website at www.buseireann.ie.", "pred_label": "__label__POS", "pred_score_pos": 0.9301593899726868}
{"content": "What is Colourful Semantics? Colourful Semantics is an intervention approach created by Alison Bryan. It is aimed at helping children develop grammar (syntax) by linking it to the meaning of words (semantics). It's an excellent way of supporting vocabulary development, spoken and written language and narratives.\nWho is Colourful Semantics suitable for?\nThis intervention can be used to help children with a variety of needs from those who are just starting to develop language and have limited vocabulary, to confident talkers who struggle to organise the grammatical content of their sentences. It is a very visual approach incorporating Makaton, colour and symbols and is therefore ideal for children with the following needs:\nSpecific Language Impairment\nDevelopmental Language Delay\nAutistic Spectrum Conditions\nDown Syndrome\nLiteracy difficulties\nEAL children\nHow does it work?\nColourful Semantics reassembles sentences after first breaking them down into thematic roles and colour coding them accordingly. The approach has four key colour-coded stages. Once these first four stages are mastered, additional levels are gradually introduced to include adverbs, adjectives, prepositions, conjunctions and negatives.\nWho can deliver this within our school?\nOnce it has been established that a child's language can be a supported in school and does not require a full SaLT diagnosis, we can work with you to set appropriate targets for individual learners. The intervention can be delivered 1:1 or in a small group. As with all of our interventions, for greatest impact in the classroom, we aim to work closely with staff to ensure we incorporate current topic vocabulary and narrative.\nWhole school approach\nThe Colourful Semantics method can also be embedded as part of a whole school approach to boost literacy attainment and phonics teaching.\nFor an informal chat about Speakwrite delivering this intervention within your school, drop us a line, give us a call.", "pred_label": "__label__POS", "pred_score_pos": 0.5718677043914795}
{"content": "Your sense of sight is a complex process that relies on the flawless function of numerous components in your visual system. Any infirmities to these eye structures may interfere with the way light rays are bent when they enter your eyes, leading to refractive errors. Here, your local eye doctor from Shady Grove Eye and Vision Care discusses four types of refractive errors:\nAstigmatism\nA cornea that is asymmetrically curved or a lens with an uneven surface may cause astigmatism. This can lead to blurry, wavy, or even distorted near- and far-range vision. It’s usually corrected with toric lenses, which have a sliced donut shape to compensate for your eyes’ structural irregularities, allowing you to see clearly at different refractive levels.\nPresbyopia\nThis refractive error is general age-related. Over time, the natural lenses of your eyes start to become more rigid, limiting their flexibility. This results in a decline in their focusing ability, making it difficult for you to see nearby objects clearly. We may recommend wearing bifocal lenses, which contain prescriptions for both your distant and near viewing ease. We also suggest undergoing a comprehensive eye exam so we can check for any other signs of age-related eye problems.\nMyopia (Nearsightedness)\nHaving an overly curved cornea or an elongated eyeball causes light to incorrectly focus in front of the retina rather than directly upon it. People with myopia can see nearby objects clearly, but distant objects appear blurry. We may advise wearing prescription eyeglasses or contact lenses to help you see better.\nHyperopia (Farsightedness)\nAn eyeball that’s unusually short or a cornea that’s too rigid may cause light to incorrectly settle at the back of your retina. People with hyperopia struggle to see nearby objects, while their far-range vision remains sharp. Wearing prescription eyewear is the standard treatment for this refractive error.\nWe may also suggest using ortho k lenses or undergoing laser eye surgery once we determine the best method for your situation. We’ll explain your condition and available options in detail during your visit. Call us today at (301) 859-4060 or fill out our contact form to schedule an appointment.", "pred_label": "__label__POS", "pred_score_pos": 0.7844812870025635}
{"content": "Published in: Psychonomic Bulletin & Review, Volume 24, Issue 6, December 2017, 1906-1914 Abstract “Knowing the place-value of digits in multi-digit numbers allows us to identify, understand and distinguish between numbers with the same digits (e.g., 1492 vs. 1942). Research using the size congruency task has shown that the place-value in a string of three zeros and a non-zero digit (e.g., 0090) is processed automatically. In the present study, we explored whether place-value is also automatically activated when more complex numbers (e.g., 2795) are presented. Twenty-five participants were exposed to pairs of four-digit numbers that differed regarding the position of some digits and their physical size. Participants had to decide which of the two numbers was presented in a larger font size. In the congruent condition, the number shown in a bigger font size was numerically larger. In the incongruent condition, the number shown in a smaller font size was numerically larger. Two types of numbers were employed: numbers composed of three zeros and one non-zero digit (e.g., 0040–0400) and numbers composed of four non-zero digits (e.g., 2795–2759). Results showed larger congruency effects in more distant pairs in both type of numbers. Interestingly, this effect was considerably stronger in the strings composed of zeros. These results indicate that place-value coding is partially automatic, as it depends on the perceptual and numerical properties of the numbers to be processed.” Written by: Javier Garcia-Orza, Alejandro J. Estudillo, Marina Calleja, José Miguel RodriguezFor full text: https://doi.org/10.3758/s13423-017-1231-x", "pred_label": "__label__POS", "pred_score_pos": 0.5080997347831726}
{"content": "Event\nBhutan’s Ministry of Health confirmed the first case of coronavirus (COVID-19) in the country on Thursday, March 5. The case was identified in a tourist who arrived at Paro International Airport (PBH) from India on Monday, March 2, and later visited a medical facility after suffering from symptoms related to COVID-19. Upon confirming the virus, the individual was placed in isolation and health officials have begun contact tracing. At least eight other passengers from the flight have been quarantined and 90 people from contact tracing are being tested for the virus.\nIn response to the confirmed coronavirus case, the country has implemented quarantine measures to prevent further spread. Schools in Thimphu, Paro, and Punakha will close for two weeks from Friday, March 6, and all international conferences and seminar are also postponed. Temporary restrictions on tourists are also in effect for 14 days to allow for monitoring and the assessment on the infection. Additional restrictions are possible as the government assesses the situation over the next two weeks.\nFurther international spread of COVID-19 is to be expected over the coming days and weeks.\nContext\nThe first case of COVID-19 was reported on December 31 and the source of the outbreak has been linked to a wet market in Wuhan (Hubei province, China). Human-to-human and patient-to-medical staff transmission of the virus have been confirmed. Many of the associated fatalities have been due to pneumonia caused by the virus.\nCases of the virus have been confirmed in numerous countries and territories worldwide. Virus-screening and quarantining measures are being implemented at airports worldwide, as well as extensive travel restrictions. On February 28, the World Health Organization (WHO) declared that the risk of spread and the risk of impact of the virus is \"very high\" at the global level.\nPneumonia symptoms include dry cough, chest pain, fever, and labored breathing. Pneumonia can be contagious and can be transmitted from human to human. The influenza virus, or the flu, is a common cause of viral pneumonia.\nAdvice\nPotentially impacted travelers are advised to monitor the situation, confirm travel itineraries, and adhere to all instructions issued by local authorities and their home governments.\nTo reduce the risk of transmission, travelers are advised to abide by the following measures:\nFrequently clean hands by applying an alcohol-based hand rub or washing with soap and water. When coughing and sneezing, cover mouth and nose with a flexed elbow or tissue; if used, throw the tissue away immediately and wash hands. If experiencing a fever, cough, and difficulty breathing, seek medical care urgently and share your previous travel history with your health care provider.\nIn the case that symptoms suggestive of respiratory illness emerge either during or after travel, travelers are encouraged to seek medical attention and share their travel history with their health care provider. Travelers returning from China, South Korea, Italy, and Iran who develop symptoms of pneumonia are advised to call emergency services before going to the doctor or hospital to prevent the potential spread of the disease.", "pred_label": "__label__POS", "pred_score_pos": 0.5845851898193359}
{"content": "Abstract\nObjective: The aims were to 1) establish which of the four algorithms for estimating residual noise level and signal-to-noise ratio (SNR) in auditory brainstem responses (ABRs) perform better in terms of post-average wave-V peak latency and amplitude errors and 2) determine whether SNR or noise floor is a better stop criterion where the outcome measure is peak latency or amplitude. Design: The performance of the algorithms was evaluated by numerical simulations using an ABR template combined with electroencephalographic (EEG) recordings obtained without sound stimulus. The suitability of a fixed SNR versus a fixed noise floor stop criterion was assessed when variations in the wave-V waveform shape reflecting inter-subject variation was introduced. Study sample: Over 100 hours of raw EEG noise was recorded from 17 adult subjects, under different conditions (e.g. sleep or movement). Results: ABR feature accuracy was similar for the four algorithms. However, it was shown that a fixed noise floor leads to higher ABR wave-V amplitude accuracy; conversely, a fixed SNR yields higher wave-V latency accuracy. Conclusion: Similar performance suggests the use of the less computationally complex algorithms. Different stop criteria are recommended if the ABR peak latency or the amplitude is the outcome measure of interest.\nBibliographical noteFunding Information:\nThis work was supported by the Carlsbergfondet and Oticon Foundation.\nKeywords ABR latency and amplitude errors Auditory brainstem response, signal quality estimators post-averaged noise estimators", "pred_label": "__label__POS", "pred_score_pos": 0.6340000033378601}
{"content": "The global\nresidential lighting fixtures market size is expected to reach USD 21.17 billion by 2025, according to a new report by Grand View Research, Inc. It is projected to expand at a CAGR of 5.9% during the forecast period. The rapid replacement of traditional lights with more energy-efficient and economical lighting fixtures is expected to remain a prominent trend. Furthermore, rising middle-class population in developing countries including China, India, Bangladesh, and Philippines as a result of urban development and increasing number of employment opportunities is projected to have a positive impact on the market.\nThe Light-emitting Diodes and Organic Light-emitting Diode (LED & OLED) led the market in 2018, contributing to over 50% of revenue share. High energy-efficiency and durability is anticipated to drive the growth. This segment is expected to witness steady growth in the upcoming years owing to the implementation of government initiatives aimed at encouraging the adoption of energy-efficient LED lighting instead of incandescent lighting.\nCeiling and wall mounted together held the largest share of the global residential lighting fixture market with over 60% of the total revenue share in 2018. These products illuminate the whole room and make it appear brighter and larger. In addition, availability of a wide range of ceiling and wall mounted fixtures appropriate for different types of homes and décor is anticipated to bode well for the product demand.\nAsia Pacific held the leading market share of more than 45% in 2018. Rising number of residential buildings in emerging economies including China, India, and Philippines on account of easy loan assistance by banks for home construction is expected to expand the use of lighting equipment. Additionally, the increasing number of smartphone users in these countries is expected to encourage manufacturers to launch products in their online stores.\nKey manufacturers include Koninklijke Philips N.V.; Cree Inc.; General Electric; Hubbell Lighting, Inc.; Acuity Brands, Inc.; Eaton Corporation; Panasonic Corporation; OSRAM Licht AG; Nichia Corporation; and Everlight Electronics Co., Ltd. New product launches is expected to remain a key competitive strategy in the forthcoming years.\nClick the link below: https://www.grandviewresearch.com/industry-analysis/residential-lighting-fixtures-market Further key findings from the report suggest: Ceiling segment generated a revenue of more than USD 4 billion in 2018 LED and OLED product segment is expected to account for a market share of 59.3% in terms of revenue by the end of 2025, owing to excellent energy efficieny of the products. Middle East and Africa is expected witness the fastest CAGR of 6.2% from 2019 to 2025. The scope for electrification along with government initiatives in African countries including Nigeria, Kenya, and Ethiopia is projected to open new avenues Asia Pacific led the residential lighting fixture market with more than 45% of revenue share Online distribution channel is expected to expand at a CAGR of 8.7% from 2019 to 2025", "pred_label": "__label__POS", "pred_score_pos": 0.767584502696991}
{"content": "Deals and volumes of investment-grade corporate bonds\nInvestment-grade corporate bonds worth ~$12.2 billion were issued in the primary market in the week ending February 5, 2016. This was lower than the $23.1 billion we saw issued the previous week, and the number of issuers fell to 12 from 14 the previous week.\nHowever, last week, the yield on investment-grade corporate bonds nudged up. As a result, the weekly returns of the T. Rowe Price New Income Fund (PRCIX) and the Janus Flexible Bond Fund Class A (JDFAX) were flat.\nMajor Issuers Issuance by quality and maturity\nFixed-rate issues formed 94.3% of the total issuance while floating-rate issues worth $0.7 billion were raised in the week ending February 5. As for the credit ratings of issues, AAA-rated issuers were the most prolific, making up 46.6%, or $5.7 billion, of the total issuance. These were followed by A-rated issuers, which formed 40.7% of the week’s issuance. BBB-rated papers formed 9.4% of the total issuance.\nIn terms of maturity, the largest chunk of issuance, making up 38.9% of all issues, was in the five-year maturity category. This was followed by the three-year maturity category, which commanded 35.6% of the total issuance, and the ten-year maturity category, which made up 12.9% of the total issuance that week.\nMeanwhile, long-term maturity categories, such as the 30-year, made up 2.9% of the total issuance, while >30-year category did not see any issuance for the fourth consecutive week. Perpetuals made up 1.2% of total issuance last week.\nIn the next part of this series, we’ll highlight the major deals from the week ending February 5, including pricing, credit rating, and yields.", "pred_label": "__label__POS", "pred_score_pos": 0.9801161885261536}
{"content": "In a recent post, I argued that labels can create a sense of community — and are therefore beneficial in some ways. Stereotypes, on the other hand, are problematic, because they restrict how we behave (girls have to be feminine, boys must like sports, etc.).\nI’m a firm believer in questioning my opinions on a regular basis — and re-thinking them, if need be. The following is a quote from writer and philosopher Jiddu Krishnamurti, who most definitely disagrees with me on labels:", "pred_label": "__label__POS", "pred_score_pos": 0.9861736297607422}
{"content": "Abrupt high-latitude climate events and decoupled seasonal trends during the Eemian Journal article, Peer reviewed Published version Permanent lenkehttp://hdl.handle.net/11250/2585412 Utgivelsesdato2018 MetadataVis full innførsel OriginalversjonNature Communications. 2018, 9:2851. 10.1038/s41467-018-05314-1 Sammendrag\nThe Eemian (the Last Interglacial; ca. 129–116 thousand years ago) presents a testbed for assessing environmental responses and climate feedbacks under warmer-than-present boundary conditions. However, climate syntheses for the Eemian remain hampered by lack of data from the high-latitude land areas, masking the climate response and feedbacks in the Arctic. Here we present a high-resolution (sub-centennial) record of Eemian palaeoclimate from northern Finland, with multi-model reconstructions for July and January air temperature. In contrast with the mid-latitudes of Europe, our data show decoupled seasonal trends with falling July and rising January temperatures over the Eemian, due to orbital and oceanic forcings. This leads to an oceanic Late-Eemian climate, consistent with an earlier hypothesis of glacial inception in Europe. The interglacial is further intersected by two strong cooling and drying events. These abrupt events parallel shifts in marine proxy data, linked to disturbances in the North Atlantic oceanic circulation regime.Abrupt high-latitude climate events and decoupled seasonal trends during the Eemian\nBeskrivelse\nOpen Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.", "pred_label": "__label__POS", "pred_score_pos": 0.7332795858383179}
{"content": "As the parent of a newborn baby, you may rely on the knowledge and experience of your medical professionals to do what it takes to get your baby here safely. To protect newborns, childbirth typically must move at the right pace and attending physicians generally need to avoid or mitigate complications. When doctors act recklessly or in a wanton manner, life-altering birth injuries could occur. These situations should be evaluated by a seasoned Troy birth injury lawyer to determine if a lawsuit is warranted. If your baby is suffering from a birth injury, your family may be entitled to compensation.\nContact a skilled medical malpractice lawyer to learn about potential legal options that could be applicable to your case. A birth injury could present many challenges in the future and may incur unexpected medical costs. Financial compensation from a negligence claim could substantially help a family address those concerns.\nCommon Causes of Birth Injuries\nBirth injuries can be caused by many different factors, some of which may be unavoidable and others of which are preventable with proper care. The majority of avoidable birth injuries typically can be linked to a few common causes which may include:\nDelay in delivering the baby Medical professionals not recognizing labor complications Failing to perform a C-section when warranted Failing to use other emergency procedures when necessary Inappropriate use of forceps, vacuum extraction, or other birthing devices Physician Negligence\nThe aforementioned causes may all be traced back to negligence by the physician or other medical care providers. The legal concept of negligence often involves four main factors and is generally used by birth injury lawyers in Troy seeking to help plaintiffs recover compensation in civil court. Typically, to demonstrate medical malpractice in a birth injury a claimant may need to show that a doctor owed them a duty of care breached the duty of care and that their reckless actions exactly and proximately caused their child’s injuries. These injuries may also need to result in damages.\nAfter a patient-doctor relationship is established, physicians typically have a duty to act in a manner that other reasonable physicians with the same level of training and experience would have acted. When the physician or other healthcare provider does not act in such a manner, they could be accused of breaching their duty of care.\nSimply breaching a duty does not always warrant a lawsuit. The breach typically must have caused an injury to the patient. In other words, there generally must be a direct and provable link between the actions of the physician and the injury that occurred.\nThere typically must also be damages incurred from the injury. These could be financial damages, physical damages, or even emotional damages. However, the plaintiff often bears the burden of proving their damages exist, as well as demonstrating how they stemmed from the defendant’s actions.\nComparative Fault and Birth Injuries\nAs found in New York Civil Practice Law & Rules §4011a, New York State generally follows a pure comparative fault law. This typically means that, when applicable, a civil court could assign a percentage of fault to the plaintiff in a birth injury case. For instance, if the mother did not follow the instructions of her doctor to remain on bed rest or take a certain medication, the mother may be found partially at fault for any ensuing damages.\nThe percentage of fault assigned to the plaintiff may reduce their compensation by the same amount. If the case does not make it to trial, this law could also be considered during settlement negotiations between the plaintiff’s Troy birth injury attorney and the defendant’s legal team.\nTalk to a Troy Birth Injury Attorney\nBirth injury cases are often complex and frequently require a lot of research and preparation prior to filing. At the same time, the circumstances surrounding a birth injury can be heartbreaking to families who want to move forward with their lives. If you and your family have suffered the devastating effects of a birth injury, consider contacting a Troy birth injury lawyer. They could examine the facts in your case and potentially help identify how a medical professional may have acted negligently.", "pred_label": "__label__POS", "pred_score_pos": 0.949220597743988}
{"content": "Abstract\nThis qualitative multicase study explored the process through which three student caregivers engaged in relationships with key infants in the context of an infant practicum course as a foundation for learning about infant development and practice. Focusing on caregiver–infant dyads, data sources included videotaped observations of caregiver–child interactions across three time points in a semester, and student caregivers’ weekly reflective notebooks and assignments. Findings from this study revealed the power and value of relationships as an essential context for learning about infant development, infant care and education, and preparation of infant professionals. Ample time and supported opportunities to develop authentic relationships with infants and their families, and a framework for reflection on relationships and practice were provided through a well-constructed and supervised infant practicum, which is recommended for both early childhood preservice students and those preparing for related disciplines. Our findings suggest that infant caregiving provides valuable professional knowledge which can be applied across the early childhood continuum.", "pred_label": "__label__POS", "pred_score_pos": 0.9340049624443054}
{"content": "Chronic subdural hematoma (cSDH) is a condition where a pool of blood slowly collects between the surface of the brain and the brain’s outer covering called the dura. This is caused by blood seeping from small, bridging veins at the surface of the brain, often as a result of a very mild trauma. This condition is often seen in elderly patients and, if the hematoma grows large enough, can cause headaches, gait imbalance, and stroke-like symptoms due to the blood pushing on the brain. The incidence of chronic subdural hematoma (cSDH) is believed to be increasing due to the aging patient population and increased use of anticoagulants and antiplatelet agents.\nSymptoms of chronic subdural hematoma (cSDH) include :\nIf a patient requires treatment for their chronic subdural hematomac (cSDH), the typical treatment involves open surgical approaches and drainage of the hematoma. However, significant research is underway to assess the role of endovascular treatments for this disease state.", "pred_label": "__label__POS", "pred_score_pos": 0.5493659377098083}
{"content": "It's appealing to ignore a sluggish drain and continue on with your regular routine in Shreveport. It's just a nuisance, right?\nIt might feel insignificant initially, but a blocked drain can result in worse—and more pricey—problems. It could be induced by hair, a grease buildup or various issues that are blocking your pipes.\nService Experts Heating & Air Conditioning can uncover the root of your blockage and get it resolved before you wind up with leaking—or worse, broken—pipes and a water-damaged house.\nWe use a high-tech video drain inspector that allows us detect what’s going on in your pipes. Our video scopes make it easy to find plumbing issues and take care of them.\nWe have the knowledge and tools to extract any size of clog that’s leading to plumbing issues in your home. Plus, all of our work is supported by a 100% Satisfaction Guarantee for a year.*", "pred_label": "__label__POS", "pred_score_pos": 0.9007309675216675}
{"content": "Cerebral palsy (CP) is a complex brain disorder that can involve both physical and cognitive disabilities. It most often develops at or near birth. It is often preventable if a physician recognizes the obvious risks that can lead to brain injuries at birth and takes...\nPersonal Injury Law Is All We Do", "pred_label": "__label__POS", "pred_score_pos": 0.9998624920845032}
{"content": "The human body is stereotypically defined by having one heart, one brain and multiple sets of appendages: arms, legs, eyes, ears… Even if all mammals, including humans, start out with the same female body construct in-utero— men’s nipples are a vestige of the original female body plan—the interplay of genetics […]\nThroughout history, society has been influenced by a series of factors such as governmental and non-governmental bodies, their laws and rules, media, education, economic factors (GDP, poverty, unemployment) science, technology, globalization and many others. If the influence spread more or less globally, very often the consequences had to be dealt […]", "pred_label": "__label__POS", "pred_score_pos": 0.5411462783813477}
{"content": "Atanasova, Dimitrinka (2019)\nMoving society to a sustainable future:The framing of sustainability in a constructive media outlet. Environmental Communication, 13 (5). pp. 700-711. ISSN 1752-4032\nMoving_society_to_a_sustainable_future_Accepted_author_manuscript.pdf - Accepted Version\nAvailable under License Creative Commons Attribution-NonCommercial.\nDownload (203kB)\nAbstract\nNews reporting on sustainability has been criticized for (1) having a limited coverage of solutions, (2) reporting on solutions with a negative bias, (3) being dominated by sources from government and mainstream business, and (4) promoting frames that prioritize the role of the market and techno-scientific solutions, which leave unchallenged the unsustainable behavior of consumer societies and the focus on economic growth. This study was the first to examine how sustainability is reported in a constructive media outlet and found that articles (1) consistently elaborated solutions, (2) described them in optimistic ways, (3) quoted various sources, and (4) developed a frame that challenged consumerism and critiqued society’s preoccupation with growth while helping to imagine a desirable sustainable future. It is thus argued that this novel, constructive approach to journalism can help move society to a sustainable future by expanding the repertoire of culturally-resonant stories to live by.", "pred_label": "__label__POS", "pred_score_pos": 0.5989903211593628}
{"content": "Cheung, Jacqueline Tak-York\nJacqueline Cheung is a recent M. Ed. graduate from the University of British Columbia, and has a position in the Ministry of Social Services in Canada.\n1997 0-7734-8544-9\nThis volume examines the learning models of workplace training. The dominant model in North America is the behavioral approach, with strong emphasis on classroom-based and formal group activities. Three emerging alternatives to this model are examined: action regulation theory, critical reflectivity model, and \"working-class adult education\" approach. This analysis provides an overview of these models, examines the retraining scheme adopted in Hong Kong in 1992, its origin and evolution, model of training, an appraisal of its results, and provides recommendations and criticisms. It includes a bibliography of recent reports, press releases, studies and speeches on the subject.", "pred_label": "__label__POS", "pred_score_pos": 0.9390204548835754}
{"content": "Abstract\nZika virus (ZIKV) is an arbovirus that caused widespread panic beginning in 2015 in northeastern Brazil due to the threatening link between infection and fetal abnormalities such as microcephaly, spontaneous abortions, and stillbirths. Since the epidemic began, the virus has been further investigated, unveiling that the long-term dangers of ZIKV infection go beyond fetal neurological impairment. Characterization of the active infection has proven difficult as only 20% of infected individuals are symptomatic. Additionally, ZIKV is often misdiagnosed due to serological cross-reactivity with similar flaviviruses such as dengue, yellow fever, and West Nile. To date, there is no approved vaccine or therapy against ZIKV, highlighting the urgent need to accurately identify active infection to help minimize the spread of the virus. Herein, we describe a highly specific and sensitive enzyme-linked immunosorbent assay to detect early active ZIKV using neutralizing human monoclonal antibodies isolated from infected patients in Brazil that do not cross-react with dengue viruses 1-4 and bind directly to a ZIKV immunodominant epitope. The calculated limits of detection of active ZIKV fall within the physiological ranges of the virus in human bodily fluids. This selective immunoassay creates the platform required for future translation toward a point-of-care assay for ZIKV, a necessity to diagnose active ZIKV in the remote regions of which it thrives.\nASJC Scopus subject areas Chemistry(all) Chemical Engineering(all)", "pred_label": "__label__POS", "pred_score_pos": 0.9934498071670532}
{"content": "Introduction: The objective of our study was to estimate the incidence of prescribing medication errors specifically made by a trainee and identify factors associated with these errors during the simulated resuscitation of a critically ill child. Methods: The results of the simulated resuscitation are described. We analyzed data from the simulated resuscitation for the occurrence of a prescribing medication error. We compared univariate analysis of each variable to medication error rate and performed a separate multiple logistic regression analysis on the significant univariate variables to assess the association between the selected variables. Results: We reviewed 49 simulated resuscitations. The final medication error rate for the simulation was 26.5% (95% CI 13.7% - 39.3%). On univariate analysis, statistically significant findings for decreased prescribing medication error rates included senior residents in charge, presence of a pharmacist, sleeping greater than 8 hours prior to the simulation, and a visual analog scale score showing more confidence in caring for critically ill children. Multiple logistic regression analysis using the above significant variables showed only the presence of a pharmacist to remain significantly associated with decreased medication error, odds ratio of 0.09 (95% CI 0.01 - 0.64). Conclusion: Our results indicate that the presence of a clinical pharmacist during the resuscitation of a critically ill child reduces the medication errors made by resident physician trainees.", "pred_label": "__label__POS", "pred_score_pos": 0.9908473491668701}
{"content": "Severe flooding occurred near the Austin metropolitan area in central Texas September 7–14, 2010, because of heavy rainfall associated with Tropical Storm Hermine. The U.S. Geological Survey, in cooperation with the Upper Brushy Creek Water Control and Improvement District, determined rainfall amounts and annual exceedance probabilities for rainfall resulting in flooding in Bell, Williamson, and Travis counties in central Texas during September 2010. We documented peak streamflows and the annual exceedance probabilities for peak streamflows recorded at several streamflow-gaging stations in the study area. The 24-hour rainfall total exceeded 12 inches at some locations, with one report of 14.57 inches at Lake Georgetown. Rainfall probabilities were estimated using previously published depth-duration frequency maps for Texas. At 4 sites in Williamson County, the 24-hour rainfall had an annual exceedance probability of 0.002. Streamflow measurement data and flood-peak data from U.S. Geological Survey surface-water monitoring stations (streamflow and reservoir gaging stations) are presented, along with a comparison of September 2010 flood peaks to previous known maximums in the periods of record. Annual exceedance probabilities for peak streamflow were computed for 20 streamflow-gaging stations based on an analysis of streamflow-gaging station records. The annual exceedance probability was 0.03 for the September 2010 peak streamflow at the Geological Survey's streamflow-gaging stations 08104700 North Fork San Gabriel River near Georgetown, Texas, and 08154700 Bull Creek at Loop 360 near Austin, Texas. The annual exceedance probability was 0.02 for the peak streamflow for Geological Survey's streamflow-gaging station 08104500 Little River near Little River, Texas. The lack of similarity in the annual exceedance probabilities computed for precipitation and streamflow might be attributed to the small areal extent of the heaviest rainfall over these and the other gaged watersheds.", "pred_label": "__label__POS", "pred_score_pos": 0.8937996029853821}
{"content": "I begin by drawing attention to the efficiencies in the pooling of longevity and investment risk that collective funded pension schemes provide over individual defined contribution (IDC) pension pots in guarding against your risk of living too long. I then turn to an analysis of those collective schemes that promise a defined benefit (DB): an inflation-proof income in retirement until death, specified as a fraction of your salary earned during your career. I consider the concepts and principles within and beyond financial economics that underlie the valuation and funding of such a pension promise. I assess the merits of the ‘actuarial approach’ to funding an open, ongoing, enduring DB scheme at a low rate of contributions invested in ‘return-seeking’ equities and property. I also consider the merits of the contrasting ‘financial economics approach’, which calls for a higher rate of contributions set as the cost of bonds that ‘match’ the liabilities. I draw on the real-world case of the UK’s multi-employer Universities Superannuation Scheme (USS) to adjudicate between these approaches. The contrasting investment strategy of London’s SAUL pension scheme, the objectives of the Pensions Regulator, the significance of the Pension Protection Fund, and the decision of Trinity College Cambridge to withdraw from USS to protect itself against being the ‘last man standing’, all figure in the discussion.", "pred_label": "__label__POS", "pred_score_pos": 0.6229684352874756}
{"content": "Maximizing resources for a leading university\nRice University’s New Emerging Science & Technology (NEST) Center is a renovated lab housed within the George R. Brown Bioengineering Lab, a building that took home R&D magazine’s “Lab of the Year” award in 1992. Challenged to design a space that would better foster “the business” of research, NEST represents a radical departure from existing lab design at Rice University.\nEarly on, the client determined that two departments would be housed in this space, but rather than claim individual territories, we co-located the departments to maximize lab space and promote interdisciplinary research. We further maximized lab space by clustering all bench and support space into one wing and all work areas in a perpendicular wing, in a completely open floor plan, thereby reducing the amount of dedicated corridor space needed. Marking collaboration zones in the laboratory areas are collaboration portals, which are defined by bright green, writable glass panels. This allows users to walk mere feet from their bench to a large writing area where multiple people can gather.\nCompared to the lab that previously occupied the space, NEST delivers 20% more lab area, 30% more bench space and a 9.5% increase in student/researcher efficiency.\nWe are sharing resources, and students and faculty from different groups can collaborate on bold new projects. We have established, decorated faculty rubbing elbows with emerging young faculty, and they will all be better researchers because of it.\nNed Thomas, Dean, George R. Brown School of Engineering, Rice University", "pred_label": "__label__POS", "pred_score_pos": 0.6072845458984375}
{"content": "A professional service robot is defined as a semi- or fully autonomous robot for automation of commercial tasks, excluding manufacturing operations.\nService robots for professional use are experiencing a technological revolution. A rapid proliferation in robot capabilities – driven by innovations in machine learning, artificial intelligence, adaptive computing and vision systems – is causing the market to nearly triple in value.\n~\nRobot Industries Association", "pred_label": "__label__POS", "pred_score_pos": 0.9685567617416382}
{"content": "Is Alcohol Testing a Violation of the ADA?\nThe Americans with Disabilities Act of 1990 (ADA) prohibits employer discrimination against individuals with disabilities and requires employers to offer reasonable accommodations to employees with disabilities who can otherwise perform the essential functions of their jobs. Employers may not ask prospective employees about the nature or severity of disabilities or require them to take a medical examination before making a job offer.\nIf an employer requires all job applicants to take a medical examination before beginning work and always makes final job offers conditional on the satisfactory result of those medical examinations, it may require disabled job applicants to complete the same examination. After a person starts work, a medical examination must be job-related and a business necessity. Alcohol testing qualifies as a medical examination under the ADA.\nTo avoid conflicting with the requirements of the ADA, alcohol testing must be intimately linked to business necessity and the essential functions of the job. In general, it should not concern an employer if an employee drinks after work or even has a drink or two over lunch — as long as that lunchtime drink does not adversely affect afternoon performance. It should be noted, however, that the ADA does not protect individuals who consume alcohol while at work.\nLikewise, an employer who knows that an employee is a recovering alcohol may not routinely subject that employee to alcohol testing if the presence of alcohol in the employee’s system would not affect his or her ability to perform the essential functions of her job or pose a significant threat to other employees or to customers. For example, an employee whose job requires him or her to perform data entry, answer the phone, scrub bathrooms, or write memos will not pose a significant threat to other employees or to customers and may be able to perform the essential functions of the job even with alcohol in his or her system. In such a case, alcohol testing would probably violate the ADA’s anti-discrimination requirements. But someone whose job requires driving a vehicle, operating heavy machinery, or performing surgery would pose a significant threat to others. So in these and similar cases, alcohol testing would not violate the ADA.", "pred_label": "__label__POS", "pred_score_pos": 0.8405730128288269}
{"content": "The objective of this scheme is to encourage undertakings to invest in their business, innovate, expand, and implement compliance directives or to develop their operations. Such undertakings which may include self-employed persons and will be supported through a tax credit representing a percentage of the eligible expenditure including wages of newly recruited employees.\nDue to significant distortions in the economy caused by unforeseen events, for those applications received in 2020, the Corporation may disburse part of the tax credit awarded as a cash grant.\nDocumentation\nApplicants are required to hold all the documentation related to their application in a separate file. This file shall be made available to the Corporation or its appointed auditor on request. The beneficiary will keep the records for ten (10) years from the issuing of the IEC.\nApplication Annexes De Minimis Declaration (2020)", "pred_label": "__label__POS", "pred_score_pos": 0.766189694404602}
{"content": "Thus, those astute leaders study and network beyond their bailiwick. Most of them consume content and make connections voraciously, both within their professional genre and beyond.\nFor example, those versatile leaders might explore content along the following lines:\nManufacturing - to understand better how to identify and mitigate bottlenecks in production. Faith-based - to understand better the search for meaning, for themselves and for pursuing worthy organizational goals. Psychology - to understand better how and why humans act, react, and interact the way they do. Marketing - to understand better how to reach target audiences with the goods and services they produce. Science - to understand better how the most current research informs practice. Health - to understand better how movement, peace, hydration, and nutrition (in both their literal and figurative forms) impact performance and longevity.\nYou get the idea. Those truly wise leaders understand that they can never understand enough, and that they most certainly cannot understand enough if their learning focus is narrow.", "pred_label": "__label__POS", "pred_score_pos": 0.775644063949585}
{"content": "Increasingly, critical realist scholars have been discussing the implications of realist theories of causality for the research methods we use in the social sciences. The usual view – which I will agree with – is that realism is compatible with a wide range of different research methods. But I will suggest that for realists there is a gap between conventional methods and the explanatory task, and then speculate a little on how we might fill that gap in practice.", "pred_label": "__label__POS", "pred_score_pos": 0.9718611836433411}
{"content": "The Iowa Women’s Foundation (IWF) has announced the launch of their new campaign to increase the recognition of child care providers as essential, professional workers. The campaign, “CAREforce for our WORKforce”, aims to provide easily-accessible public information regarding how to support child care providers during and after the pandemic.\nThe announcement was announced on the same day as National Provider Appreciation Day, which recognizes child care professionals yearly on the Friday before Mother’s Day.\n“Child care workers are not babysitters — they are highly-trained professionals who provide the critical early childhood support kids need for success later in life,” said Dawn Oliver Wiand, Executive Director for IWF. “They’re essential for parents. They’re essential for businesses. And essential for society as we know it.”\nIn celebration, IWF will distribute window clings, stickers, posters, and yard signs proudly displaying the new CAREforce for our WORKforce logo, and a web page launch is currently in the works.\nIndividuals looking to support their local child care professionals can visit https://iawf.org.careforce for a list of supplies and services that can be donated. Those interested in participating in the CAREforce for our WORKforce campaign as a volunteer may contact dawn@iawf.org for more information.", "pred_label": "__label__POS", "pred_score_pos": 0.7316396236419678}
{"content": "Purchase this article with an account.\nor\nHisashi Tanigawa, Haidong Lu, Gang Chen, Anna Wang Roe; Functional subdivisions in macaque V4 revealed by optical imaging in the behaving Macaque monkey. Journal of Vision 2008;8(6):227. doi: https://doi.org/10.1167/8.6.227.\nDownload citation file:\n© ARVO (1962-2015); The Authors (2016-present)\nIn macaque V4, it has been proposed that there are several subdivisions based on patterns of connectivity and visual topography (Zeki, 1971; Maguire and Baizer, 1984). Zeki (1983) reported that color selective cells were more frequently found in the anterior bank of lunate sulcus (V4 proper), as compared with the cortex on the prelunate gyrus (V4A). However, this finding was based on qualitative observation and there has been no study to confirm this finding. Here, we studied the functional organization of V4 using intrinsic signal optical imaging in two alert macaque monkeys and examined whether there is any functional subdivision in V4 in relation to color, luminance, and orientation preferences. Intrinsic signals were obtained through a chronic chamber over the portion of V4 representing foveal and parafoveal visual space ([[lt]]1.5° and 3–7° eccentricity, respectively). To reveal feature representation, a patch (0.25–8°) or full-screen stimulus filled with isoluminant color-varying or achromatic luminance-varying gratings was presented while the monkey was performing a fixation task. Visual activations in V4 showed a stimulus-size dependence: small grating patches activated the cortex more strongly than the full-screen gratings, consistent with the presence of strong surround suppression. In the foveal V4, color/luminance and orientation mapped in the different cortical locations. Color and luminance-sensitive regions were located posteriorly, close to the lunate sulcus (within 2 mm), alternating with a band-like appearance (color/luminance domains). The width of these domains was approximately 0.5 mm. In a region anterior to these domains, orientation-sensitive regions were observed (orientation domains). These two types of domains were largely separated but with some overlap. Within the color/luminance domains, different colors activated separate sub-domains. This functional compartmentalization was also observed in the parafoveal V4. These results indicate that there are distinct functional subdivisions in V4, which appear to correspond to the subdivisions proposed previously (V4 proper/V4A).\nThis PDF is available to Subscribers Only", "pred_label": "__label__POS", "pred_score_pos": 0.635856032371521}
{"content": "Abstract\nWhen looking at visual stimuli, context often easily affects elements of perception and cognition such as aesthetic evaluation, memory, and time perception. However, the relationships between aesthetic evaluation and time perception as influenced by context are not fully understood. This study's aim was to examine whether context can influence not only aesthetic evaluation but also time perception. To achieve this, a temporal reproduction task was used. Participants viewed stimuli in either an art context or a realistic context. Identical affective pictures were presented in one of three durations (2500 ms, 4500 ms, or 6500 ms) and the participants reproduced their perceived viewing time for each picture. The pictures were rated as more pleasant when viewed in the art context compared to the realistic context. Additionally, the perceived duration of identical visual stimuli differed according to the particular context. Thus, contextual differences were found to be attributed to different operations of a switch within the internal clock. In sum, context can influence both aesthetic evaluation and time perception.\nKeywords Aesthetic evaluation Affective picture Context Perceived duration Time perception ASJC Scopus subject areas Visual Arts and Performing Arts History Applied Psychology", "pred_label": "__label__POS", "pred_score_pos": 0.9985528588294983}
{"content": "Abstract\nIntroduction: Vision is often an essential capacity for the interaction between individuals and their environment. Yet, for some individuals, an impaired visual system alters that opportunity. Visual loss can be lifelong, present from birth; for others, it can be progressive or abrupt. For some individuals, particularly those who lose vision later in life, the loss of vision is associated with a corresponding loss of independence, and impact on their emotional status. A lifespan perspective regarding visual impairment (VI) holds that the experience of VI since birth or early childhood is qualitatively different from the experience of individuals who acquire VI later in life. For example, in early childhood, VI impacts psychomotor and cognitive development that relies upon visual information processing and places challenges on the educational system, which must provide appropriate supports. In contrast, when acquired later in life, VI may place challenges on the ability to complete tasks of daily living, be independent, and engage in leisure activities, but not affect learning status or how knowledge is shared. While VI may impact the trajectory of lifespan development, it also taps an individual's (and their family's) ability to cope effectively with the challenges VI elicits. Professionals working with individuals with VI must take into consideration the developmental trajectory and cognitive, behavioral and psychological sequelae of VI when assessing neurocognitive functioning, to determine the most appropriate educational, vocational, and/or rehabilitative setting to optimize quality of life.\nOriginal language English (US) Title of host publication Principles and Practice of Lifespan Developmental Neuropsychology Publisher Cambridge University Press Pages 277-298 Number of pages 22 ISBN (Electronic) 9780511674815 ISBN (Print) 9780521896221 DOIs State Published - Jan 1 2010 ASJC Scopus subject areas Psychology(all)", "pred_label": "__label__POS", "pred_score_pos": 0.8258438110351562}
{"content": "According to a report released in March by the United Nations Office for the Coordination of Humanitarian Affairs (OCHA), there were about 450,000 displaced persons in Tanganyika, the most affected region among the four provinces of the former Katanga, DRC. But in the past five months, it seems that this number has doubled. In Kalemie, the province capital, there are more displaced people than local inhabitants: for every ten people, six are migrants.\nTo support displaced people in the region, AVSI is currently implementing two projects. The first project’s main goal is to guarantee that 15,000 children living in Kalemie have access to quality education. Funded by Fonds Communs Humanitaires, the project responds to the current crisis in DRC supporting the most vulnerable victims: children who have lost everything.\nAs part of this project, AVSI is financially supporting the schools located near the displaced population camps, so the schools can accommodate new students, train teachers and school directors to ensure that greater attention will be on those who have already suffered major traumas, and provide school materials, such as kits for teachers and soccer balls and toys for the moments of leisure.\nThe second project is the Rapid Response to Population Movements (RRPM) that has been extended for the eighth year and whom AVSI is one of the main partners.\nIn the next six months, RRPM aims to reach displaced people in the most inaccessible areas of the four provinces of the ex-Katanga (Tanganyika, Lualaba, Haut-Lomami and Haut-Katanga), where other NGOs have no access. The main goal is to assist those who have been displaced for less than three months, providing essential goods, and organizing interventions in the fields of education, health and hygiene in collaboration with the International Rescue Committee (IRC).", "pred_label": "__label__POS", "pred_score_pos": 0.7445039749145508}
{"content": "Tether recorded a transaction higher than Bitcoin last Thursday, setting a new historical record in its daily trading volume of approximately US $20 billion, while Bitcoin remained around 17 billion.\nTether’s trade volume exceeds its historical highs\nThe volume of Tether has been increasing throughout the year, at the same time that all the pairs of operations that were previously led by Bitcoin have been decreasing significantly because the stablecoins are becoming more popular to be negotiated against the altcoins than BTC.\nTether’s total offer has experienced rapid growth since 2017, reached a new all-time high of 4.27 billion units compared to $ 2.7 billion last year. Tether is used in between 40% and 80% of all transactions in the Huobi and Binance exchange houses, the latter of which now offers loans based on Tether guarantees.\nTether has really good liquidity in China. Asian operators over the counter (OTC) avoid banking restrictions using stablecoin. They maintain that a significant part of their movements comes from Chinese customers who use Tether to move assets beyond the strict capital controls of their country, such movements being estimated at around 30 million dollars a day between Russia’s border with China, using USDT.\nDespite the creation of new dollar-anchored tokens, the growing market preference for Tether can be evidenced. The dominance of the Tether among its competition has always been superior. The token currently stands at 81.77% dominance in the market with respect to its competition.\nTether’s new Blockchain\nTether has migrated the issuance of its Omni Layer blockchain tokens to Ethereum. During the last week, transactions based on ERC-20 (tokens based on the Ethereum Blockchain) have increased considerably with respect to those of Omni. On Thursday, there were about 100,000 ERC20 transactions compared to 39,000 Omni transactions. The utilization of the Ethereum network has skyrocketed by 90%. In the last month, Tether paid the computers that process transactions in the Ethereum digital book USD $260,000 in fees.\nThe change to the ERC-20 standard is because the Ethereum Blockchain has much lower network transaction rates and much faster confirmation times (15-30 seconds) compared to the Omni Blockchain. There are currently approximately 2.5 billion USDT in the Omni network and 1.5 billion USDT using the Ethereum network.\nConsidering that the aforementioned characteristics may be attractive to active traders, it is objective to think that the issuance of Tether in Ethereum continues to grow in relation to the issuance in Omni, which will have as a consequence that the market demand for the Tether increases progressively.\nPolemic around tether and its influence on the price of Bitcoin\nThe relationship between the issuance of Tether with respect to the price of Bitcoin is a controversial issue in the crypto world due to the lack of clarity about USDT financial statements and the direct relationship with Bitfinex.\nThe main stablecoin in the market is immersed in a quiet complex legal controversy. The New York prosecution filed charges against Tether and Bitfinex in the Supreme Court, claiming the cover-up of losses of $850 million from the Bitfinex company with funds that were intended to support the issuance of Tether; and also demonstrating that the token was not fully backed by the dollar; charges that both companies deny. However, this trend seems to have no impact on the growth of the currency.\nChinese merchants use the Tether to liquidate their broader portfolios in global exchanges such as Binance, OkCoin or Huobi. This affects the Bitcoin market because traders and exchange houses use this cryptocurrency to obtain fiduciary liquidity. Exchange houses like Kraken and Bitfinex offer these pairs against Bitcoin. When investors buy Tether using fiat money, the emission and demand of the token increases, which also increases the total market supply. Most Bitcoin transactions are in exchange with Tether.", "pred_label": "__label__POS", "pred_score_pos": 0.6162682771682739}
{"content": "The winners of the Family Law Awards 2020 were announced at 4pm during a much-anticipated virtual awards ceremony. Over the past ten years, the Family Law Awards has recognised the leading players in...\nThe Department of Health has launched a 12-week consultation on a revision of the UK Health Departments Code of Practice and Guidance on Genetic Paternity Testing Services (March 2001), which is being amended to reflect changes in the law since 2001.\nThe Department is seeking views from major stakeholders in this area for their views on the following three questions:\ndoes the revised guidance adequately address the changes in UK law since publication of the Code in 2001?;\nwill the arrangement, whereby UK Health Departments issue voluntary guidance on paternity testing services, be sufficient in ensuring the continued application of good practice in the future?;\nif not, what other measures or arrangements do you believe should be put in place to help maintain good practice across the board?.\nThe consultation will run from 4 February to 5 May 2008.", "pred_label": "__label__POS", "pred_score_pos": 0.8396456241607666}
{"content": "Concerns around global health issues concerning COVID-19 (Coronavirus) have led to many companies implementing flexible and remote work, both temporarily and permanently.\nFear not! This shift from the traditional office environment to a global remote workforce does not spell disaster for the wellness and engagement of your employees. In fact, by structuring a clear plan, utilizing technology, and incentivizing behaviors, your workforce can become healthier and more productive than ever before!\nIn this eBook, we outline the steps your organization can take to build a thriving, remote corporate wellness program.", "pred_label": "__label__POS", "pred_score_pos": 0.5838885307312012}
{"content": "Skull base osteomyelitis (SBO) defined as an inflammation of bony structures of the cranial base, is rare condition with substantial morbidity and mortality. It typically involves temporal bone and manifested as otologic symptom and cranial neuropathy. Central skull base osteomyelitis (CSBO) is atypical form of SBO that involves the sphenoid and clivus and related to non-otogenic conditions. We present an unusual case of CSBO presented with ischemic stroke and multiple cranial nerve involvement. A diabetic women of 45 years old, with a previous history of right otalgia without otorrhea and severe headache, admitted with sudden left hemiplegia and controlateral multiple cranial nerve (CN) palsies. Cerebral imaging investigations (CT and MRI scans) showed ischemic infraction secondary to the occlusion of the right internal carotid artery (ICA) and radiological evidence of invasive osteomyelitis on the right side of the central skull base with contiguous lateral sinus thrombosis. Broad spectrum antibiotics and anticoagulant therapy was initiated with unfavorable outcome. Based on thorough review of the literature, arterial cerebrovascular complications revealing CSBO are extremely rare and the diagnosis is often challenging for the clinician.\nLeila Tamaoui, Mounia Rahmani, Chaimae El Jemli, Meriem Fikri, Maria Benabdeljlil and Saadia Aidi", "pred_label": "__label__POS", "pred_score_pos": 0.9882076382637024}
{"content": "Coronavirus (COVID-19) update – 26 May\nMettis continues to operate within the guidelines and recommendations provided by the UK Government, Public Health England and the World Health Organisation. Paramount is the health, safety, wellbeing and welfare of our people.\nWith air travel down over 90% and barely a day passing between new announcements of airlines around the world cancelling or suspending orders for new aircraft, significant cuts to delivery rates and other critical decisions, we continue to scale back our commercial aerospace operations accordingly, furloughing employees in the areas affected.\nOur military operations are less affected with customers requiring us to deliver components according to existing plans and the Ministry of Defence classing our employees as ‘essential workers’ due to the nature of their work.\nWe continue to monitor the changing situation daily and are actively engaged with Government departments and agencies, our customers and suppliers.\nGovernment guidance confirms that manufacturing workers can travel to work (details here) and extensive measures to protect all employees who continue working with us remain in place, including:\nThe provision of personal protective equipment including material masks that can be washed and gloves for all our people. A rigorous cleaning regime carried out by a dedicated, full-time cleaning team. In addition we are carrying our regular, site-wide deep cleans, including our air conditioning systems to ensure they’re circulating fresh air. The provision of sanitation kits for all teams across our site which include cloths, surface cleaners and anti-bacterial spray. Hand sanitiser in high-traffic areas including clocking stations, rest areas and other key locations. To meet the increased demand, we’re now producing extra hand sanitiser in our state-of-the-art laboratory onsite. Shielding of those with known medical conditions. Requesting people to carry out their roles remotely where possible. Large meetings are not taking place and are replaced by virtual conferences. Robust communications including a comprehensive guidance pack provided to all operational managers and shared with their teams, SMS updates to all employees who have signed up as well as Coronavirus information posters displayed in all areas across our site on noticeboards, on our internal TV system and in break areas. Unless business critical, visitors and contractors are not permitted on our site and, those who are, will be screened prior to entry. Delivery drivers are restricted to their cabs. Travel is restricted and meetings, unless business critical, cancelled.\nWe truly appreciate everything our talented people are doing to help us keep delivering during these challenging times.", "pred_label": "__label__POS", "pred_score_pos": 0.5904325246810913}
{"content": "PRIMARY OBJECTIVE:\nI. To assess the objective response rate (complete and partial responses), following the\nadministration of cabozantinib for 12 weeks in patients with locally advanced biopsy-proven\nnon-metastatic clear cell renal cell carcinoma (ccRCC) prior to undergoing surgery.\nSECONDARY OBJECTIVES:\nI. To assess the safety, and tolerability of neoadjuvant cabozantinib.\nII. To determine the clinical outcome (disease-free survival [DFS], overall survival [OS]) of\npatients with non-metastatic ccRCC who treated with neoadjuvant cabozantinib.\nIII. To evaluate the surgery related outcomes.\nIV. To evaluate correlative studies, including biomarkers, quality of life, and\nfrailty/sarcopenia assessment of patients with non-metastatic ccRCC who treated with\nneoadjuvant cabozantinib.\nOUTLINE:\nPatients receive cabozantinib orally (PO) once daily (QD) for 12 weeks in the absence of\ndisease progression or unacceptable toxicity.\nAfter completion of study treatment, patients are followed up every 3 months.\nInclusion Criteria:\n- Patients with renal mass consistent with a clinical stage ≥ T3Nx or TanyN+ or deemed\nunresectable by surgeon.\n- Renal cell carcinoma with clear cell component on pre-treatment biopsy of the primary\ntumor.\n- Eastern Cooperative Oncology Group (ECOG) performance status ≤ 1.\n- Patients must have adequate organ and marrow function, based upon meeting all of the\nfollowing laboratory criteria within 14 days before first dose of study treatment:\n- Absolute neutrophil count (ANC) ≥ 1500/mm³ (≥ 1.5 GI/L) without granulocyte\ncolony-stimulating factor support.\n- White blood cell count ≥ 2500/mm³ (≥ 2.5 GI/L).\n- Platelets ≥ 100,000/mm³ (≥ 100 GI/L) without transfusion.\n- Hemoglobin ≥ 9 g/dL.\n- Alanine aminotransferase (ALT), aspartate aminotransferase (AST), and alkaline\nphosphatase (ALP) ≤ 3 x upper limit of normal (ULN). ALP ≤ 5 x ULN with\ndocumented bone metastases.\n- Total bilirubin ≤ 1.5 x ULN (for subjects with Gilbert's disease ≤ 3 x ULN).\n- Serum albumin ≥ 2.8 g/dl.\n- Serum creatinine ≤ 1.5 x ULN or calculated creatinine clearance ≥ 40 mL/min (≥\n0.67 mL/sec) using the Cockcroft-Gault equation:\n- Males: (140 - age) x weight (kg)/(serum creatinine [mg/dL] × 72)\n- Females: [(140 - age) x weight (kg)/(serum creatinine [mg/dL] × 72)] × 0.85\n- Urine protein/creatinine ratio (UPCR) ≤ 1 mg/mg (≤ 113.2 mg/mmol).\n- No hormonal therapy, chemotherapy, immunotherapy, or any other systemic therapy for a\nmalignancy, in the 5 years prior to current study enrollment.\n- Sexually active fertile subjects and their partners must agree to use medically\naccepted methods of contraception (eg, barrier methods, including male condom, female\ncondom, or diaphragm with spermicidal gel) during the course of the study and for 4\nmonths after the last dose of study treatment.\n- Female subjects of childbearing potential must not be pregnant at screening. Females\nof childbearing potential are defined as premenopausal females capable of becoming\npregnant (ie, females who have had any evidence of menses in the past 12 months, with\nthe exception of those who had prior hysterectomy). However, women who have been\namenorrheic for 12 or more months are still considered to be of childbearing potential\nif the amenorrhea is possibly due to prior chemotherapy, antiestrogens, low body\nweight, ovarian suppression or other reasons.\n- Capable of understanding and complying with the protocol requirements and must have\nsigned the informed consent document.\nExclusion Criteria:\n- Evidence of metastatic disease on pre-treatment imaging.\n- The subject has received of any type of cytotoxic, biologic or other systemic\nanticancer therapy for kidney cancer.\n- The subject has received any other type of investigational agent within 28 days before\nthe first dose of study treatment.\n- Known brain metastases or cranial epidural disease.\n- Concomitant anticoagulation with oral anticoagulants (eg, warfarin, direct thrombin\nand Factor Xa inhibitors) or platelet inhibitors (eg, clopidogrel). Allowed\nanticoagulants are the following:\n- Low-dose aspirin for cardioprotection (per local applicable guidelines) is\npermitted.\n- Low-dose low molecular weight heparins (LMWH) are permitted.\n- Anticoagulation with therapeutic doses of LMWH is allowed in subjects without\nknown brain metastases who are on a stable dose of LMWH for at least 6 weeks\nbefore first dose of study treatment, and who have had no clinically significant\nhemorrhagic complications from the anticoagulation regimen or the tumor.\n- The subject has prothrombin time (PT)/international normalized ratio (INR) or partial\nthromboplastin time (PTT) test ≥ 1.3 × the laboratory ULN within 14 days before the\nfirst dose of study treatment.\n- The subject has uncontrolled, significant intercurrent or recent illness including,\nbut not limited to, the following conditions:\n- Cardiovascular disorders:\n- Congestive heart failure New York Heart Association Class 3 or 4, unstable\nangina pectoris, serious cardiac arrhythmias.\n- Uncontrolled hypertension defined as sustained blood pressure (BP) > 150 mm\nHg systolic or > 100 mm Hg diastolic despite optimal antihypertensive\ntreatment.\n- Stroke (including transient ischemic attack [TIA]), myocardial infarction\n(MI), or other ischemic event, or thromboembolic event (eg, deep venous\nthrombosis, pulmonary embolism) within 6 months before first dose.\n- Gastrointestinal (GI) disorders including those associated with a high risk of\nperforation or fistula formation:\n- The subject has evidence of tumor invading the GI tract, active peptic ulcer\ndisease, active inflammatory bowel disease (eg, Crohn's disease),\ndiverticulitis, cholecystitis, symptomatic cholangitis or appendicitis,\nacute pancreatitis, acute obstruction of the pancreatic duct or common bile\nduct, or gastric outlet obstruction.\n- Abdominal fistula, GI perforation, bowel obstruction, or intra-abdominal\nabscess within 6 months before first dose. Note: Complete healing of an\nintra-abdominal abscess must be confirmed before first dose.\n- Clinically significant hematemesis, or hemoptysis of > 0.5 teaspoon (2.5 ml) of\nred blood, or other history of significant bleeding (eg, pulmonary hemorrhage)\nwithin 12 weeks before first dose.\n- Cavitating pulmonary lesion(s) or known endotracheal or endobronchial disease\nmanifestation.\n- Other clinically significant disorders that would preclude safe study\nparticipation.\n- Serious non-healing wound/ulcer/bone fracture.\n- Uncompensated/symptomatic hypothyroidism.\n- Moderate to severe hepatic impairment (Child-Pugh B or C).\n- Major surgery (eg, GI surgery, removal or biopsy of brain metastasis) within 8 weeks\nbefore first dose of study treatment. Complete wound healing from major surgery must\nhave occurred 1 month before first dose and from minor surgery (eg, simple excision,\ntooth extraction) at least 10 days before first dose. Subjects with clinically\nrelevant ongoing complications from prior surgery are not eligible.\n- Prolongation of the QT corrected for HR using Fridericia's method (QTcF) interval\ndefined as > 500 msec per electrocardiogram (ECG) within 28 days before first dose of\nstudy treatment. Note: If a single ECG shows a QTcF with an absolute value > 500 ms,\ntwo additional ECGs at intervals of approximately 3 min must be performed within 30\nmin after the initial ECG, and the average of these three consecutive results for QTcF\nwill be used to determine eligibility.\n- Pregnant or lactating females.\n- Inability to swallow tablets.\n- Previously identified allergy or hypersensitivity to components of the study treatment\nformulations.\n- Diagnosis of another malignancy within 2 years before first dose of study treatment,\nexcept for superficial skin cancers, or localized, low grade tumors deemed cured and\nnot treated with systemic therapy. Patients with Gleason 6 (3+3) prostate cancer with\nprevious treatment or on active surveillance may also be allowed on protocol.", "pred_label": "__label__POS", "pred_score_pos": 0.868736743927002}
{"content": "Our 2020 Healthcare Communications salary and workforce insight survey found that across the sector the average salary for a male worker in the USA is 4.1% higher than the average female salary.\nThe average male salary is $145,200 which is 4.1% higher than the average female salary of £139,427.\nThis has reduced slightly compared to 2019 where there was a gap of 4.5% (where the male average salary of $128,575 and female average salary of $123,014.\nWe are very pleased to see that the gender pay gap has reduced and look forward to seeing further progress towards pay parity in 2021.\nYou can view our summary report or request a free copy of our full detailed report that include more insights into the sector including average salaries, employer’s hiring plans, the most in-demand skills employers are looking for and the impact of COVID-19.", "pred_label": "__label__POS", "pred_score_pos": 0.5880938768386841}
{"content": "The 3D printing industry has seen $3B in all-time funding through Q3 2019. Let’s examine the graphic below and analyze which of the 9 3D printing categories are leading the sector in total funding amounts.\nAs the analysis demonstrates, the Manufacturers category has the highest all-time funding at $1.9B, followed by Applications at $421M and 3D Scanners with $417M in funds raised.\nVisit our report overview page to learn more about our full 3D Printing coverage.\nCategories\nNecessary cookies are absolutely essential for the website to function properly. This category only includes cookies that ensures basic functionalities and security features of the website. These cookies do not store any personal information.\nAny cookies that may not be particularly necessary for the website to function and is used specifically to collect user personal data via analytics, ads, other embedded contents are termed as non-necessary cookies. It is mandatory to procure user consent prior to running these cookies on your website.", "pred_label": "__label__POS", "pred_score_pos": 0.9562246203422546}
{"content": "A legal challenge against New York State’s “Green Light Law” has been been dismissed by a judge, which will in effect allow undocumented immigrants to obtain driver’s licenses in the Empire State.\nAs noted in Fox News, Rensselaer County Clerk Frank Merola’s legal efforts were shot down as a judge determined that Merola lacked standing because he could not reasonably lay claim to “cognizable injury.” The judge emphasized that his ruling was not related to the legality or illegality of the law itself, but was, instead, a procedural decision, acknowledging: “To the dissatisfaction of the parties and public-at-large, courts are at times unable to pass upon the merits of a case for one reason or another.”\nMerola’s defeat follows a similar dismissal against Erie County Clerk Michael Kearns in November, who argues the law championed by Governor Andrew Cuomo is both dangerous and in violation of federal law.\nAs the 13th state to provide illegal immigrants with access to driver’s licenses, New York now joins with California, Nevada, Utah, Colorado, New Mexico, Washington, Illinois, Vermont, Massachusetts, Maryland, Delaware, and Washington in carrying out the controversial policy. The District of Columbia and Puerto Rico likewise do so within their territories, according to City and State.\n“You do not need a Social Security card to apply for a license or permit,” reads a portion of New York State’s Department of Motor Vehicles webpage. However, applicants do need to provide documentation that proves the individual’s name, date of birth, and state residency. Among the combination of documents accepted by New York include: a foreign birth certificate, a border crossing card, and even an expired foreign driver’s license–so long as it has not been expired for two years or more.\nDespite the multiple legal challenges, Democrats in the state, such as State Sen. Luis Sepúlveda, are hailing the new policy as a political, economic, and humanitarian victory. “This is a major step forward for all New Yorkers as we keep building New York to live up to its full potential of equity, opportunity and justice,” Sepúlveda declared. “We also look forward to the significant economic and safety benefits the law will bring to communities across our state.”\nWritten by Red Blue Divide editorial staff", "pred_label": "__label__POS", "pred_score_pos": 0.8264738917350769}
{"content": "byWed 4 March 2020\nAndy Pham\nIt is a collaboration between mentor and mentee who works together to identify goals that are specific to the individual’s role and aligned to corporate objectives. The mentor should be supportive and listen to the ideas of the mentee. This is critical as it guarantees that mentee will know “what is expected of me”, which is another key drive of engagement and performance. It also frames the conversation in a meaningful way. Are the goals on track or not? Why? What can the individual do to improve? What can others do to support? If the performance or behavior under question does not change, the mentor needs to remind the mentee of the goal and hole him/her accountable. Mentor set priorities and had ability to work toward stated as success could be defined as a progressive realization of a predetermined goal. Mentor amplified limited power by empowering mentee to take on shared challenges, seeking to surround with the most talented people representing a wide range of skills that could be helpful in achieving the goals. Mentor in collaboration with mentee helps to set goals, to move forward these goals, and to advice on what course of action mentee should take. Furthermore, mentor coaches mentee to build the processes necessary to collaborate on a strategy on how to best implement the project.\nMentoring is a long-term commitment with a broader range; include guidance toward professional education and career choices.", "pred_label": "__label__POS", "pred_score_pos": 0.9715954661369324}
{"content": "Abstract\nCalendar-dated tree-ring sequences offer an unparalleled resource for high-resolution paleoenvironmental reconstruction. Where such records exist for a few limited geographic regions over the last 8,000 to 12,000 years, they have proved invaluable for creating precise and accurate timelines for past human and environmental interactions. To expand such records across new geographic territory or extend data for certain regions further backward in time, new applications must be developed to secure “floating” (not yet absolutely dated) tree-ring sequences, which cannot be assigned single-calendar year dates by standard dendrochronological techniques. This study develops two approaches to this problem for a critical floating tree-ring chronology from the East Mediterranean Bronze-Iron Age. The chronology is more closely fixed in time using annually resolved patterns of\n14C, modulated by cosmic radiation, between 1700 and 1480 BC. This placement is then tested using an anticorrelation between calendar-dated tree-ring growth responses to climatically effective volcanism in North American bristlecone pine and the Mediterranean trees. Examination of the newly dated Mediterranean tree-ring sequence between 1630 and 1500 BC using X-ray fluorescence revealed an unusual calcium anomaly around 1560 BC. While requiring further replication and analysis, this anomaly merits exploration as a potential marker for the eruption of Thera.\nOriginal language English (US) Pages (from-to) 8410-8415 Number of pages 6 Journal Proceedings of the National Academy of Sciences of the United States of America Volume 117 Issue number 15 DOIs State Published - Apr 14 2020 Keywords Annual C Mediterranean Bronze Age Thera eruption Tree rings ASJC Scopus subject areas General", "pred_label": "__label__POS", "pred_score_pos": 0.563188910484314}
{"content": "A17: No, a certificate can only be issued if the CAB is able to evaluate all the applicable requirements of ISO/IEC 17021-1 (9.3.1.2 Stage 1 and 9.3.1.3 Stage 2) through a complete and effective audit of the client’s management system, followed by a successful review and decision making activities. However, this could change for specific schemes.", "pred_label": "__label__POS", "pred_score_pos": 0.6338369250297546}
{"content": "Abstract\nBackground: Hürthle cell carcinoma (HCC) is a rare form of thyroid carcinoma and is considered an oxyphilic variant of follicular thyroid carcinoma. However, little is known about its biological characteristics or clinical behavior. We conducted a retrospective study to determine whether the prognosis of HCC differs from that of ordinary follicular thyroid carcinoma (OFC). Methods: The subjects were the 558 patients with follicular thyroid carcinoma who underwent initial surgery at our institution between 1989 and 2010 and consisted of 73 patients with HCC and 485 patients with OFC. There were 410 females and 148 males, and their median age was 51 years. A univariate analysis was conducted in relation to cumulative cause-specific survival (CSS) according to the Kaplan-Meier method for the following variables: age at the time of initial surgery, gender, tumor size, invasiveness, distant metastasis at presentation, and histological type (HCC vs OFC). Differences between groups were analyzed for significance by the log-rank test. Multivariate analysis was performed by using the Cox proportional hazard model. Results: A total of 4 patients (5.5 %) in the HCC group had distant metastasis compared with 106 patients (21.9 %) in the OFC group. Significant factors in relation to CSS in the univariate analyses were age, tumor size, and invasiveness, but there were no significant differences between the HCC group and the OFC group. Multivariate analysis showed that age, tumor size, and distant metastasis at presentation were significant factors. Conclusions: HCC does not have a poorer prognosis than OFC.\nASJC Scopus subject areas Surgery Oncology", "pred_label": "__label__POS", "pred_score_pos": 0.596478283405304}
{"content": "Description\nCiticoline is a powerful nootropic supplement best known for its potential to enhance memory and protect the brain against memory loss.\nBenefits Memory Enhancement Increased Mental Energy Better Focus and Concentration Potentiating and Amplifying Other Nootropics How To Take?\nAnywhere from 250–1000 mg, either in a single dose or in two doses is considered safe and effective. 1000mg is the maximum within the same day.", "pred_label": "__label__POS", "pred_score_pos": 0.9864527583122253}
{"content": "Abstract\nWe are facing unprecedented phosphorus (P) challenges, namely P scarcity associated with increasing food demand, and an oversupply of P fertilisers, resulting in eutrophication. Although we need a multidisciplinary approach to systematically enhance P-use efficiency, monodisciplinary studies still prevail. Here, we propose to tighten the P cycle by identifying P-efficient crop genotypes, integrating four plant strategies: increasing P-acquisition efficiency, photosynthetic P-use efficiency and P-remobilisation efficiency, and decreasing seed phytate P concentrations. We recommend P-efficient genotypes together with diversified cropping systems involving complementary P-acquisition strategies as well as smart P-fertiliser management to enhance P-use efficiency in agriculture dependent on soil P status. These strategies will reduce P-fertiliser requirements and offsite environmental impacts, while enhancing seed quality for human and livestock nutrition.", "pred_label": "__label__POS", "pred_score_pos": 0.6087905168533325}
{"content": "Committed to achieving incident-free operations\nPrevent injury to personnel and damage to offshore and onshore assets with our full range of Dropped Object Management and Inspection services, fine-tuned according to the industry best practices and in compliance with relevant regulatory requirements.\nDropped objects have been known to present a constant risk and play a significant role in incidents in the oil and gas industry, including offshore drilling and onshore production plants — affecting both productivity and safety.", "pred_label": "__label__POS", "pred_score_pos": 0.7734048962593079}
{"content": "“Engage your patient.” So important. So many different ways to approach it. Consumerism in healthcare is on a steep climb, yet due to a lack of clarity as to the best approach to patient engagement, many organizations offer a less-than-ideal, far-from-comprehensive strategy to tackle the initiative. Patients are no longer satisfied with a healthcare experience that is riddled with inefficiencies and shrouded in mystery. And baby steps won’t work. Effective patient engagement strategies impact all areas of your organization, and they all must be addressed simultaneously.\nConsider these five areas: 1. Build your strategy on a mobile platform\nToday’s consumer relies on mobile technology for everything from shopping to banking, but healthcare organizations have lagged other industries in reaching the patient with mobile solutions. As more innovative organizations deliver patient engagement strategies using mobile technology, consumers will begin to choose providers based on the ease in communicating with them. The proliferation of mobile platforms in healthcare will transform the consumer experience and drive changes in consumer behavior.\n2. Tackle financials early and often\nConsumers have more financial responsibility for their healthcare than ever before and are now the nation’s second largest payer. It’s a rapid and dramatic shift, and healthcare organizations can effectively address the challenge through their patient engagement strategy. Consumers want more transparency with regard to the prices of healthcare services, need to understand their responsibility, and welcome the convenience of paying their portion on a mobile device.\n3. Embrace mobile clinical innovations\nFrom the habitually healthy to the chronically ill, consumers are more knowledgeable about and actively involved in and their own health status than ever. This trend continues to grow and healthcare organizations must understand and address it. Clinical outcomes can improve by pointing patients to clinical resources that align with your organization, and encouraging them to think about their health and do their own research between visits. Your patient engagement strategy also must embrace advances in virtual care and telehealth.\n4. Keep administrative needs at the forefront\nMany of your organization’s most repeatable tasks deliver the most salient benefits from your patient engagement strategy. And patients embrace these administrative solutions readily. From appointment scheduling to requesting prescription refills to general office communications, a mobile platform improves patient relations while reducing time spent by your office staff. The number of patients that expect mobile solutions for administrative services will continue to grow, and healthcare organizations can use this trend as a competitive differentiator.\n5. Always drive patients to the mobile front door\nIdentifying the right mobile solutions for patient engagement is an ongoing challenge for healthcare organizations, and it’s not as straightforward as it should be. Tried-and-true technology vendors are not always the ones that have the best solutions. Often it’s new vendors, making the challenge of identifying and sourcing these vendors time-consuming and risky. Commonwealth Health Advisors helps healthcare organizations develop a comprehensive patient engagement strategy and execute it.", "pred_label": "__label__POS", "pred_score_pos": 0.6298988461494446}
{"content": "Grandparent Visitation and Children's Wishes How do the Child's Wishes Weigh in on Grandparent Visitation Cases in New York?\nChild custody, visitation, and maintenance cases in the state of New York follow a very important standard. Any court, judge, or divorce attorney handling a case involving children must put the best interests of the child or children first in any matter. This simply means that no decisions should be made that might harm the mental or physical health of the child in any way. Of course, there are many different components that go into helping a court decide what the best interests of any child might be. For instance, the courts might consider the earning potential of the parents, the ability of any parent to provide a child with the continued emotional and financial support they need, and even the desires or wishes of the child in question.\nAs a child custody attorney in New York, Mr. Shapiro has worked on numerous cases wherein the wishes of the child have been considered an important element in the discussion of that child's best interests. Of course, it's worth noting that the child's wishes will only be taken into consideration in a case where the child is deemed to be in a state, or at an age that allows them to make decisions fairly about their future. Even when a child's wishes are considered, they may not be adhered to if the court believes that they're not in the best interests of the child.\nThe Wishes of the Child in Grandparent Visitation\nThe desires and wishes of a child can be considered in numerous cases surrounding divorce, including child visitation, custody, and parenting time. Importantly, when it comes to addressing visitation cases in the courts of New York, it's worth remembering that people beyond the parents can also apply for visitation rights. For instance, grandparents may apply for visitation rights when one or both of the parents involved in a case argue against their ability to see the grandchild. In this case, section 72 of the New York Domestic Relations Law can provide guidance on the guidelines that must be followed, along with Section 651 of the Family Court Act.\nMr. Shapiro has plenty of experience as a divorce lawyer dealing with cases that involve complicated relationships between divorcing parties and the grandparents of a child in a visitation case. As he often reminds his clients, there are many complex issues to consider when it comes to determining the possibilities of grandparent visitation. However, grandparents who can show that there are circumstances wherein they should be allowed to see the child can ask to obtain visitation rights. Once again, with grandparents, the decisions that the courts make will be based on the simple principle of \" what's best for the child.\"\nAs mentioned above, the expressed wishes of a child to continue seeing, or maintain a relationship with a grandparent or grandparents may be considered when determining best interests. However, this isn't always the case. The courts of New York generally give more weight to the desires expressed by older children who understand their circumstances clearly and are capable of making reasoned decisions without the input of a parent disrupting their choices. Younger children can easily be swayed by parents who don't want them to see a grandparent. This concept brings to light an interesting point that comes up in many grandparent visitation cases, regarding the animosity between the grandparents seeking visitation and the custodial parent.\nProviding Visitation Rights to Grand Parents\nThrough years of experience in the New York and Long Island courts, Mr. Shapiro has become very familiar with cases that can help to inform his clients about the nature of child custody and visitation situations. As a child custody attorney, he often draws attention to this information to guide his clients. For instance, in one particularly important case related to grandparent visitation, the courts outlined that in certain cases where the grandparents in question must turn to legal processes to obtain visitation rights, there is likely to be some animosity between grandparents and custodial parents.\nUltimately, the courts understand that the feelings of the parent can often influence the expressed wishes of a child in any case. That's why a child's desires are only a single factor in a range of elements that a court considers during its determination. Although grandparent visitation cases are less common these days, the courts have provided insights into the factors they consider when making their rulings. For instance, they may look at:\nThe emotional and mental impact of a child not being allowed to see grandparents The documented history of conflict that may exist between the grandparents and parent which may negatively affect the child. Whether the grandparents have ever acted as a primary caregiver for the child. Whether the grandparents have been shown to have a positive and nurturing relationship with the child in the past. Do You Need Help Getting or Opposing Visitation Rights?\nIf you're currently involved in a case seeking visitation rights so you can spend more time with your grandchildren, it's important to ensure you have the right support at your side. The law and mediation office of Darren M. Shapiro can offer guidance and support into child visitation cases and custody issues. To learn more or book your free (up to a half hour free) initial consultation, please call (516) 333-6555.", "pred_label": "__label__POS", "pred_score_pos": 0.5675088167190552}
{"content": "In Maryland, the value of a business interest acquired during the marriage is considered marital property, even if it is owned and operated by only one spouse.\nUpon divorce, the Court must determine the “fair market value” of a spouse’s business interest, which is what a willing buyer would pay a willing seller, neither being under the compulsion to act and both having reasonable knowledge of all relevant facts.\nHowever, a spouse’s “personal goodwill” in the business is their non-marital property, not subject to equitable distribution by the Court. “Personal goodwill” is the part the business value which is directly attributable to the reputation and success of the spouse owner.\nBusiness valuation in divorce is a complex issue in divorce cases, often requiring forensic analysis of business records and an industry professional testimony.\nOn July 16, 2012", "pred_label": "__label__POS", "pred_score_pos": 0.9671173095703125}
{"content": "Requests for self-managed abortion via a telemedicine service increased by 27% from March 20, 2020, to April 11, 2020, in the United States in the wake of widespread lockdowns and shelter-in-place directives because of the COVID-19 pandemic, based on data from a provider of such services.\nAccess to abortion care is challenging in many areas under ordinary circumstances, but the disruption of the COVID-19 pandemic led to many states suspending or limiting in-clinic services, wrote Abigail R.A. Aiken, MD, PhD, of the University of Texas at Austin and colleagues.\n“As a result, people may increasingly be seeking self-managed abortion outside the formal health care system,” they said.\nIn a research letter published in, the investigators reviewed request data from Aid Access, a telemedicine service that provides medication for abortion at up to 10 weeks’ gestation for users who complete an online consultation form. They also collected data on the implementation and scope of COVID-19–related abortion restrictions by state.\nThe analysis included all 49,935 requests made between January 1, 2019, and April 11, 2020.\nOverall, the rate of requests for self-managed medical abortions increased significantly, by 27%, during the period from March 20, 2020, to April 11, 2020, which reflected the average period after clinic restrictions or closures at the state level. A total of 11 states showed individually significant increases in requests for self-managed medical abortions, with the highest of 94% in Texas and the lowest of 22% in Ohio. In these 11 states, the median time spent at home was 5% higher than in states without significant increases in requests for self-managed medical abortions during the same period. These states also had “particularly high COVID-19 rates or more severe COVID-19–related restrictions on in-clinic abortion access,” the researchers noted.\nPatients want alternatives to in-person care\n“Our results may reflect two distinct phenomena,” Dr. Aiken and associates wrote. “First, more people may be seeking abortion through all channels, whether due to COVID-19 risks during pregnancy, reduced access to prenatal care, or the pandemic-related economic downturn. Second, there may be shift in demand from in-clinic to self-managed abortion during the pandemic, possibly owing to fear of infection during in-person care or inability to get to a clinic because of childcare and transit disruptions,” they explained.\nThe study findings were limited by the inability to measure all options for women to achieve self-managed abortions and a lack of power to detect changes in states with low request numbers or where restrictions were implemented at later dates, the researchers noted. However, the results suggest that telemedicine services for medication abortion should be a policy priority because patients may continue to seek alternatives while in-clinic services remain restricted, they said.\nIn fact, “the World Health Organization recommends telemedicine and self-management abortion-care models during the pandemic, and the United Kingdom has temporarily implemented fully remote provision of abortion medications,” the researchers wrote. However, similar strategies in the United States “would depend on sustained changes to the U.S. Food and Drug Administration’s Risk Evaluation and Mitigation Strategy, which requires patients to collect mifepristone at a hospital or medical facility, as well as changes to state-specific laws that prohibit remote provider consultation,” Dr. Aiken and associates concluded.", "pred_label": "__label__POS", "pred_score_pos": 0.7970479726791382}
{"content": "Test candidates with case-studies on real world situations with variance in how you evaluate\nAuthor custom case-study based assessments and evaluation schemes\nAnalyse evaluation results against expert benchmarks for different skill levels\nMake authored or selected case-study assessments available online for delivery and reference\nCase-study based assessments requires test-takers to consider constraints, information and desired outcomes before making decisions\nTest-takers are engrossed with the real-world situations which tests their problem-solving ability without relying on mindless memorization\nA multi-dimensional representation of the assessment allows test-takers and administrators to analyse strengths and weaknesses with detailed data on performance while allowing productive career-based feedback\nDifficult to determine whether a candidate will be a good \"culture-fit\" and \"role-fit\".\nAssess emotional intelligence, respond to situations and overall outlook to determine the fitment into the role and organizational culture.\nDecision making skills are not tested in the conventional hiring process.\nAuthess tests the candidate’s critical thinking and decision-making skills by posing constraint laden situations and targets.\nPlacing candidates in roles according to their skill level is a demanding task.\nAuthess compares performance and skill against set benchmarks to help place candidates appropriately.", "pred_label": "__label__POS", "pred_score_pos": 0.6556651592254639}
{"content": "Silicon is the most widely used material in modern electronics industry, both in Taiwan and the world, due to its natural abundance, semiconductor/doping property, mass production, and capability to be densely integrated. It is a long-awaited goal to amalgamate photonics with the advantages of silicon, i.e. silicon photonics. In the field of electronics, the key success relies on nonlinear components, such as transistors, that can control electric signal via voltage or current, i.e. all-electric control. Similarly, in silicon photonics, light-control-light, or equivalently all-optical control, is a highly desirable function. However, the optical nonlinearity of silicon is too weak to achieve efficient all-optical control.\nUnder the support of MOST “Outstanding young scientist project”, MAGIC program, and regular projects for one decade, as well as long-term support from NTU Molecular Imaging Center, Prof. Shi-Wei Chu of NTU Physics has formed an international and national collaboration team, including Prof. Junichi Takahara and Prof. Katsumasa Fujita of Osaka University, Prof. Xiangping Li of Jinan University, Dr. Kung-Hsuan Lin of Academia Sinica, Dr. Chih-Wei Chang of NTU, and Prof. Kuo-Ping Chen of NCTU. In two recent publications in top journal “Nature Communications”, they jointly revealed that silicon nanostructures, which exhibit special electromagnetic resonance mode that can enhance light interaction, plus thermally isolated nano-environment that enables efficient temperature increase, can provide 3-4 orders of magnitude enhancement of optical nonlinearity over bulk silicon. The underlying mechanism is photothermal interaction between light and silicon nanostructures, but impressively, the response time is a few orders faster than common photothermal responses, reaching nanosecond scale. The giant and fast nonlinearity allows nearly 100% all-optical modulation of scattering light from a single silicon nanoparticle, at GHz speed. Furthermore, we combine the giant nonlinearity and super-resolution techniques to realize 40-nm resolution, featuring not only one order resolution enhancement, but also label-free imaging in silicon nanostructures. These results open up a new avenue in silicon photonics, toward the goal of all-optical circuits with silicon.", "pred_label": "__label__POS", "pred_score_pos": 0.5187811851501465}
{"content": "Metaglip (glipizide/metformin) may interact with the following drugs: beta-blockers such as propranolol; anticoagulants like warfarin; azole antifungals such as miconazole; chloramphenicol; clofibrate; insulin; monoamine oxidase inhibitors (MAOIs), such as phenelzine; nonsteroidal anti-inflammatory drugs (NSAIDs); phenylbutazone; probenecid; quinolones; salicylates; sulfonamides, such as sulfamethoxazole; and thiazolidinediones, like pioglitazone. Additional medications that can interact with Metaglip include: calcium channel blockers, like nifedipine; corticosteroids such as prednisone; diazoxide; diuretics, such as furosemide or hydrochlorothiazide; estrogen; hormonal contraceptives; isoniazid; nicotinic acid; phenothiazines, such as chlorpromazine; phenytoin; rifampin; sympathomimetics, such as albuterol; pseudoephedrine; thyroid hormones such as levothyroxine; gemfibrozil amiloride; cimetidine; digoxin; morphine; procainamide; quinidine; quinine; ranitidine; triamterene; trimethoprim, or vancomycin.\nContinue Learning about Antidiabetic\nImportant: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.", "pred_label": "__label__POS", "pred_score_pos": 1.000006079673767}
{"content": "Effectively managing software licensing costs and compliance risks during an M&A transaction is critical. Find out how to avoid the legal and financial risks, save costs and stay in control of your software investments.\nThe Oracle Unlimited License Agreement (ULA) can be a valuable tool for your organization. Although they are designed to alleviate the many worries of software license management, you can still face significant financial, le...\nDon’t expose your organization to large SAP penalties and ongoing maintenance charges. Understanding the common cases of indirect usage will help save your organization from the financial risks of being non-compliant. Here...\nDon’t be caught in a non-compliant position during an audit. Be proactive and perform routine self-audits. The key to a successful self-audit is complete understand of your entitlements. This is a challenging feat considerin...", "pred_label": "__label__POS", "pred_score_pos": 0.89864182472229}
{"content": "Abstract\nThere is an imperative need for effective control of bovine tuberculosis (BTB) on a global scale and vaccination of cattle may prove to be pivotal in achieving this. The oral and parenteral use of a heat-inactivated Mycobacterium bovis (M. bovis) vaccine has previously been found to confer partial protection against", "pred_label": "__label__POS", "pred_score_pos": 0.5015659332275391}
{"content": "Choosing Sides: Doing Interviews in a Divided Field\n“You are not going to agree with this, but I voted leave.” A participant in my research told me this early on in an interview. I had not shared with her my personal opinion on the EU, but from my accent (which does not sound Scottish) she discerned I was from continental Europe and decided that I probably did not agree with Brexit. During interviews I am not trying to find out how the interviewee voted in the EU referendum, but it is a difficult topic to avoid when discussing Europe.\nNavigating a divided field\nIn the past six years, the Scottish people have taken part in two divisive referendums. In 2014 they were asked whether Scotland should become an independent state (55% chose to remain part of the UK) and in 2016 they were asked whether the UK should remain a member of the EU (in Scotland, 62% chose to remain part of the EU). Both referendums left a significant mark on the current political landscape in Scotland. My research focusses on the personal dimension of this: how do Scottish people, in particular supporters of Scottish independence, identify with Europe and what does the concept of Europe mean to them. To do this, it is important for me to get beyond the results of the referendums in my fieldwork, but this is not always straightforward.\nThe problem with discussing politics in Scotland today is that opinions are immediately pigeonholed into the answers of the referendums: participants in my research often identify themselves (and others) first as yes/no or remain/leave. It is of course uncommon that reality is as binary as that: it is a messy and personal calculation of values, beliefs, influences and experiences. Participants are hardly ever completely\nyes or remain without a conditional but. To get a result which is valuable for my research, I aim to break through the referendum replies as early as possible in the interviews and uncover what is hidden below. Placing myself in the field\nAt the same time as providing us with an opportunity to research beyond the suggested binaries of the referendums, ethnographic fieldwork forces the researcher to reflect on his/her own connection to the communities being researched. In my case, that reflection starts by asking and being asked where I fit on the yes/no, leave/remain spectrum.\nI have experimented with sharing my own opinions on these matters and keeping them to myself during fieldwork. Sharing my stance can have different effects: if it is in agreement with the participant, the interview feels more at ease, resulting in a form of ‘safe space’ which can be highly beneficial for the results. On the other hand, disagreement can lead to a more tense interview with defensive arguments. Although perhaps not as comfortable, these defensive arguments can also be a useful contribution to the research. Both scenarios involve me being judged by the participants and have an inevitable influence on the interview. But not sharing my opinion at all is also difficult, as it creates an interview with a clear interviewer (who is neutral) and an interviewee (who has opinion, which forms the centre of the interview). This feels less natural, as neutrality is rare in the current political landscape.\nI prefer taking a (natural) honest approach instead of an (artificial) neutral approach, I believe it brings me closer to achieving the final aim of the interview: to create an atmosphere whereby all participants feel they can share their opinions openly and can be respected for them. If achieved, this has allowed me to move the interview beyond the inevitable referendum results.\nPhoto by Alastair Mackie.\nDid you enjoy reading this? Share it with your social network.", "pred_label": "__label__POS", "pred_score_pos": 0.5174014568328857}
{"content": "Does an allergen need to be declared if it disappears during processing?\nStandard 1.2.3 of the Australia New Zealand Food Standards Code broadly requires the declaration of allergens that are present in a food product. However, the wording of this Food Standard might cause manufacturers to wonder whether the declaration of the allergen applies when that ingoing substance is expected to no longer be present in the final product by the time it is sold. This article explores this issue and sets out the relevant allergen labelling requirements using the scenario of an ingredient that disappears during processing.", "pred_label": "__label__POS", "pred_score_pos": 0.9922854900360107}
{"content": "Did You Get a Stimulus Check for Someone Who Died?\nThe CARES Act did not provide a mandate to return stimulus money that was mistakenly sent by the IRS to dead people. Now the IRS wants this money back. It would be less expensive to return it to them now, even if the taxpayer must negotiate a payment plan. Otherwise, the IRS has two years to file a lawsuit to get the money back plus the interest that accrues from the date of the first request.\nWhy Did Dead People Receive Stimulus Checks?\nThe IRS sent stimulus payments to approximately 1.1 million dead people that total nearly $1.4 billion. To quickly get money in taxpayers’ hands, the IRS sent direct deposits, checks, or debit cards to individuals who filed tax returns in 2018 and 2019. Taxpayers who died before 2020 were not removed from the IRS records.\nWho Is Entitled to a Stimulus Payment?\nThe stimulus payment that many Americans received is not free money. It is a tax credit that is paid in advance of filing an income tax return in 2021. Stimulus funds are intended for those who were alive for at least part of 2020 and might file a federal income tax return for the year. If an individual died before 2020, they would not file a return in 2021 and are not entitled to a stimulus check.\nThose who are eligible to receive a stimulus payment under the CARES Act include individuals who:\nHave a valid social security number or are married and filing jointly with someone who does Are not a nonresident alien Cannot be claimed on someone else’s tax return Is an individual and not an estate or trust What to Do with Stimulus Payments Sent to the Deceased?\nNow the IRS wants the stimulus money that was mistakenly sent to deceased taxpayers back. They have provided guidance on how to return stimulus funds and uncashed checks. They have canceled checks that have not yet been cashed. If checks were cashed, the money must be returned to the IRS. Recipients must also return any money received via direct deposit or a debit card intended for a deceased person.\nIf a surviving spouse received a payment for a deceased spouse, he or she must return the portion that is meant for the decedent. The amount returned should be $1,200 unless the adjusted gross income was more than $150,000.", "pred_label": "__label__POS", "pred_score_pos": 0.9473178386688232}
{"content": "Two crises that could not be more different and yet are closely linked. In the wake of the corona crisis, governments are adopting strict measures and funds are flowing in billions to cushion the economic fallout. Many climate activists would wish for this determination to save the climate. What can we learn from the corona crisis for the climate crisis? What role does the media have? And what influences our society’s actions in these crises?\n*The dialogue will be carried out in German", "pred_label": "__label__POS", "pred_score_pos": 0.9702644348144531}
{"content": "This paper from the European Journal of Preventive Cardiology may be of interest. It provides an update on the core components of cardiac rehab as outlined in the European Association of Preventive Cardiology 2010 statement.\nRead it here: Ambrosetti M, Abreu A, Corrà U, Davos CH, Hansen D, Frederix I, Iliou MC, Pedretti RF, Schmid JP, Vigorito C, Voller H. Secondary prevention through comprehensive cardiovascular rehabilitation: From knowledge to implementation. 2020 update. A position paper from the Secondary Prevention and Rehabilitation Section of the European Association of Preventive Cardiology. European Journal of Preventive Cardiology. 2020 Mar 30:2047487320913379.", "pred_label": "__label__POS", "pred_score_pos": 0.8203803896903992}
{"content": "Pope Francis, the leader of the Catholic Church, expressed support for same-sex civil unions in the new documentary\nFrancesco. He stated that gay people are children of God and said, “What we have to create is a civil union law. That way, they are legally covered.” Do his remarks signal a shift for the Roman Catholic Church, and how significant are they in the global context of LGBT+ rights? In many countries, cultural and religious beliefs are formidable barriers to more inclusive LGBT legislation. The current status of global LGBT rights can be mapped on a continuum from countries where homosexuality is criminalized (68 countries, including 11 that include the death penalty) to countries where same-sex marriage is legal (27 countries). The remaining countries fall somewhere in between, ranging in the degree of protections and rights afforded LGBT populations Americans may underestimate the immense power and influence that the Pope and the Roman Catholic Church have in many countries, particularly in Eastern Europe, Latin America, and Africa. Beyond cultural and religious influence, the Roman Catholic Church is involved in legislation in many countries. For example, after Belize decriminalized homosexuality in 2016, the Roman Catholic Church of Belize filed an appeal to reinstate the criminalization. The Pope’s pro-civil unions statement could have major implications in many countries. This is not the first time Pope Francis has expressed support for the LGBT community. As archbishop in Buenos Aires, he endorsed civil unions for gay couples. In 2013, he said, “If someone who is gay and searches for the Lord and has good will, who am I to judge?” However, this is his clearest and most progressive statement on the matter since becoming Pope, and it suggests not only tolerance but legal coverage for LGBT families. While these LGBT-tolerant statements signal increased acceptance of LGBT populations by the Roman Catholic Church, nothing has changed in terms of official doctrine or policy—and Pope Francis is still decidedly against gay marriage within the church. The reluctance to change church policy could be connected to the Catholic Church’s expanding presence in the Southern Hemisphere, where church leadership and parishioners are generally less likely to accept homosexuality. This statement comes as an important message to LGBT Catholics and aligns with Pope Francis’ generally more tolerant and inclusive tone (particularly compared to his predecessor, who connected same-sex marriage to the Antichrist). It may also serve as a message condemning violence committed against LGBT individuals in an effort to make it clear that people cannot be committing this violence in the church’s name. This message may lead some Catholics to examine their views, such as those in Poland, where “LGBT-free zones” have recently been established across the country (supported by senior members of the Catholic Church), and LGBT Poles face significant discrimination and violence.", "pred_label": "__label__POS", "pred_score_pos": 0.6484005451202393}
{"content": "In this op-ed, Eryn Wise, Jicarilla Apache/Laguna Pueblo, and communications director for Seeding Sovereignty, discusses two fiercely traditional, two-spirit warriors from history that embody the spirit of women’s resistance. To learn more and support our work, please visit www.seedingsovereignty.org .\nThrough the month of March, Women’s History Month “commemorates and encourages the study, observance and celebration of the vital role of women in American history,” according to the official Women’s History Month website. But what about the stories and roles of women that predate the founding of America? There are not many written accounts of the vital roles the original women of this nation had, and yet their descendants and histories cloak the land.\nOne such account came to my attention in the form of a love story between a Chihenne Chiricahua Apache woman named Lozen and a Mescalero Apache woman named Dahteste, that was shared with me at a discussion on two-spirit wellness. (Two-spirit is a name for people in Indigenous culture who carry the duality between the sacred feminine and sacred masculine within them, though definitions vary per Indigenous nation and person).\nIt was a brief retelling that was part of a much larger discussion, but for so many reasons and all at once, I was brought to tears. Listening to another two-spirit person introduce a love story that centered on two openly queer, traditional Apaches rocked me to my core. I have long known about these women, but never heard anyone introduce them in the context of being two-spirit people, or partners.\nI heard in this retelling that even as a child, Lozen demonstrated prolific abilities beyond her years. She emerged as a leader within her community before becoming a medicine woman\nand a warrior for her tribe. Throughout her life (1840-1889), she eschewed the traditional roles of Apache women, favoring the art of war, never married a man, and was often described as being more masculine than other men in her tribe. Her brother, Chief Victorio, described her as his “right hand” and “a shield to her people,” according to the Encyclopedia of Lesbian, Gay, Bisexual and Transgendered [ sic] History in America.\nWhile her physicality, strength, and fearlessness was deeply honored, she was also a highly renowned and respected medicine person, possessing a wealth of knowledge about the medicinal properties of plants and minerals. Because she was deeply connected to the earth and its elements, her people honored her ability to detect danger and enemies when they were near. When in ceremony Lozen would sing, extend her arms, and turn in a circle until her palms tingled, which let her know where the enemies were coming from. After her brother was killed and journeyed to the spirit world, she banded with Goyatła (aka Geronimo or, “One Who Is Yawning”) to exact revenge on the colonizers that had stolen him and their land, according to KQED. In what is now known as southern New Mexico, she met the woman she would soon come to love, Dahteste.\nAccording to Cristoso Apache, writing for the Qualia Folk Encyclopedia of Gay Folklife, Dahteste was also a warrior since her youth and, despite being married with children, spent a significant amount of time riding with Cochise’s band against the current of Western Expansion. Some years later, she joined Goyatła’s band and rode alongside both him and Lozen. Unlike her partner Lozen, Dahteste was known for being a well-kempt woman who was fluent in English and acted as a translator for the bands that she traveled with. After helping Geronimo escape from detainment at the San Carlos Reservation in 1885, she, with help from Lozen, began negotiating treaties of peace for their people. One such treaty stated that after a two-year, voluntary imprisonment, the Apaches would have their freedom. American leaders at the time dismissed this treaty, and despite having been a mediator and scout for the U.S. Calvary, her loyalty to both her people and the U.S. Army did not prevent her eventual arrest alongside Goyatła and Lozen\nThe only photo that survives of Dahteste and Lozen was taken after they’d been captured, before they were separated. In the photograph, they are seated close together, along with Geronimo and other warriors in front of the trains that would soon carry them away in cattle cars to exile in Florida and Alabama. Having eluded capture for over a decade, Lozen would die as a prisoner of war at Mount Vernon in Mobile, Alabama, of tuberculosis at age 49, never to see her home or partner again.\nDahteste’s story continued after she was taken and held as a prisoner of war in St. Augustine, Florida. She remained there for eight years in an internment camp, managing to survive pneumonia and tuberculosis, and years later and still a prisoner, was shipped to Fort Sill, Oklahoma. There she lived for another nineteen years before being given permission to join the Mescalero Apache in New Mexico where she remarried, refused to again speak the English language, and lived out the rest of her life among her relatives. Eve Ball, who interviewed Dahteste before her death, wrote: “Dahteste to the end of her life mourned Lozen.”\nToo many people remember Lozen and Dahteste without acknowledging the fact they were two-spirits, fiercely devoted to the land and their people, who were in love before being violently separated by colonization. I was told my entire life that there were no Apache women who were \"that way,\" only to find out that there actually were — and that they the fiercest of them all. This critical part of Indigenous, women’s, and two-spirit history reminds us that loving who you love doesn’t make you any less of a warrior. It is imperative that we fight the erasure of our ancestor’s narratives, and work to reclaim our own.", "pred_label": "__label__POS", "pred_score_pos": 0.5396929979324341}
{"content": "Informal settlements are crowded places where entire families often share a single room.\nKibera, located within the Kenyan capital of Nairobi, is one such place.\nResidents told BBC Africa that they are worried about insufficient water, sanitation, and hygiene, and about the virus spreading within the community.\n\"We are being told we must wash our hands for at least 20 seconds every time we touch things. That water is too much. We don't have money.\"\nIn informal settlements like Kenya's Kibera, where millions of people live at close quarters, many fear self-isolation is not possible. pic.twitter.com/MOsStIdjSu\n— BBC News Africa (@BBCAfrica) March 23, 2020", "pred_label": "__label__POS", "pred_score_pos": 0.5321893692016602}
{"content": "8/9 December 2020\nThe MHRA (Medicines & Healthcare products Regulatory Agency) GPvP (Good pharmacovigilance practice) inspectorate recently published their latest inspection metrics report.\nDuring the period 01 April 2014 to 31 March 2015, the MHRA conducted a total of 48 pharmacovigilance inspections. Approximately 29% of these inspections were of marketing authorisation holders (MAH) that had not previously undergone a MHRA pharmacovigilance inspection. The largest proportion of inspections (21 inspections) was performed as routine re-inspections (i.e. of MAHs who had previously undergone a pharmacovigilance inspection).\nA total of 27 Critical, 169 Major and 155 Minor findings were identified during this period. The number of Critical findings identified during this reporting period had increased from the previous period (19 Critical findings) and were found during 17 of the 48 inspections that were performed.\nThe majority of Critical findings were reported in relation to the maintenance of reference safety information, representing 29% of all Critical findings identified. Critical findings associated with reference safety information were (again) characterised by failures and significant delays to submit safety variations to update the safety sections of SPCs (summaries of product characteristics) and PILs (patient information leaflets).\nIn this reporting period, Critical deficiencies associated with signal management represented the next largest proportion of findings identified (26% of all Critical findings). A safety signal is information on a new or known adverse event that is potentially caused by a medicine and that warrants further investigation. These signals can be generated from several sources such as spontaneous reports, clinical studies and scientific publications. Seven critical findings were reported and these were associated with:\nIn some instances the persistent non-compliance had had a measurable impact. Subsequent completion of signal detection activities had resulted in new signals being identified and updates to product information.\nFurther Critical findings were identified in relation to:\nA single Critical finding was identified in each of the following areas:\nThere were no Critical findings in relation to non-interventional programmes compared to four reported during the April 2013-March 2014 period.\nThe topic areas representing the major proportion of inspection findings remain associated with key pharmacovigilance activities and outputs such as ICSR management, signal management and reference safety information.\nTo find out further details please see the complete Pharmacovigilance inspection metrics report available on GOV.UK.", "pred_label": "__label__POS", "pred_score_pos": 0.5521495342254639}
{"content": "Always welcoming new patients!\nA dental implant is a replacement tooth that is secured into the jaw with a titanium post that is surgically positioned beneath the gum line by a specialist. Once the specialist has inserted the post and it has healed, Dr. Gradeless will place the replacement tooth onto it permanently.\nIf your teeth or jaw have experienced decay due to gum disease that is not fixable with a dental filling, crown, or veneer, dental implants could be your solution. Dental implants are used to replace missing teeth after extraction or dental trauma. Many prefer implants over dentures because they are more secure and feel more natural.\nThough they serve a similar purpose, they aren’t quite the same. Many patients find dentures uncomfortable, especially if they have sore spots in their mouths or something is misaligned. Dental bridges, on the other hand, must be attached to teeth (or implants) on either side of the space left by the missing tooth. Dental implants replace individual teeth and are a permanent solution to missing teeth. Patients often say they look and feel more natural than dentures.\nHealthy gums and a strong and healthy jawbone are necessary to support the post of the implant. If your bone has decayed from disease, bone grafting may help to ensure you have a stronger jawbone to support a dental implant. Or, if there is not enough bone between your jaw and your sinuses, a sinus lift may be a solution to get you ready for an implant.", "pred_label": "__label__POS", "pred_score_pos": 0.5753160715103149}
{"content": "Posted by Hotze Vitamins on 11/12/2020 to High Blood Pressure\nIn a day and age when doctors rely so heavily on drugs for every ailment, you may not realize that there are many things you can do to naturally lower your blood pressure. Incorporating these tips into your life will not only help keep your blood pressure in check, but also benefit your overall health.\nHere are Dr. Hotze's 10 tips for lowering blood pressure naturally:\n1. Detox Regularly - Our bodies are constantly bombarded with toxins and chemicals from our environment. These toxins are found in dry cleaning solutions, pesticides sprayed in our homes, the foods we eat, body lotions and soaps, air pollution, outgassing from synthetic carpets and many other products. These toxins cause inflammation in the arteries, leading to high blood pressure and coronary artery disease.\n2. Eliminate Sugar and Simple Carbohydrates - Avoid simple carbohydrates such as bread, pizza, pasta, white rice and potatoes, which are all starches that are quickly converted to sugar in your body. Sugar leads to weight gain and causes high blood pressure.\n3. Avoid Trans Fatty Acids - Trans fatty acids are vegetable oils that have been heated to give them an indefinite shelf life. They damage the lining of your arteries, causing high blood pressure. Trans fatty acids are found in processed food products, salad dressings, margarine, donuts, cookies, crackers, chips, fried foods, and muffins. Avoid any food that has \"partially hydrogenated vegetable oil\" on the label.\n4. Maintain an Ideal Body Weight - Weight gain can cause high blood pressure. With added weight, your extra fat tissue needs oxygen and nutrients which call for the blood vessels to circulate more blood to that tissue. This causes the heart to work harder to pump more blood through additional blood vessels, which in turn causes more pressure on the artery walls, which increases blood pressure.\n5. Quit Smoking - The nicotine in cigarette smoke causes he arteries to stiffen and narrow, which increases blood pressure.\n6. Exercise Regularly - Regular physical activity keeps your heart strong so that it can keep pumping blood effectively. When your heart has to work harder to pump, that causes more force on your arteries, increasing your blood pressure.\n7. Keep Stress to a Minimum - Stressful situations can cause your blood pressure to spike. During stress, your body produces hormones which temporarily increase your blood pressure by causing your heart to beat faster and your blood vessels to narrow.\n8. Restore and Balance Hormones - Testosterone and thyroid hormones have a significant positive effect on blood pressure. Testosterone dilates the coronary arteries, increasing blood flow to the heart and lowering blood pressure. When thyroid hormone is given to hypothyroid individuals who have high blood pressure, the hypertension is often completely reversed.\n9. Magnesium - Magnesium relaxes the arterial walls, lowering blood pressure.\n10. Dr. Hotze's Blood Pressure Support - Blood Pressure Support by Dr. Hotze helps regulate blood pressure naturally. It is a premium blend of herbs that has been designed to provide your heart with optimal support.\nWe are here to help.\nDo you have questions about your health concerns and your vitamin and supplement needs? Call our Certified Holistic Nutritionists and Vitamin Consultants today at 281-646-1659. It will be our privilege to serve you.", "pred_label": "__label__POS", "pred_score_pos": 0.6143392324447632}
{"content": "J2 Servid\nAvoiding the consequences of a poorly secured cargo is essential.\nDuring transport, the pallets being transported move and the cargo shifts. Such movement can be due to abrupt stops, sudden accelerations, sharp bends… Moreover, if the pallets are not fully loaded, this situation can be even more complicated. These movements often cause the transported goods to shift and fall and these can be damaged. This is known as the\n\"domino effect\".\nPreventing cargo movements during transport through a good securing system will avoid unwanted costs, claims, and all kinds of problems. At J2 Servid we have different securing systems to prevent cargo movement during transport. All our securing systems have been designed and tested to prevent damage to goods and they all respond to different needs for securing and stowing the cargo, depending on its volume, weight, type... They include lashing belts, composite and textile strapping, protective awnings, edge protectors, anti slip products, etc.\nSpecifically, to prevent the domino effect and cargo movements when transporting pallets, at\nJ2 Servid we propose Niupack as a solution. This system does not require expensive investments and has been tested on hundreds of road trips with over 4,000 kilos of compression resistance.\nThe flexibility and ease of use of this system, which prevents cargo movement during transport, means that it can be adapted to the needs of a variety of industries: food, beverages, chemicals, pharmaceuticals, cosmetics, etc. It is also available in different sizes and formats.", "pred_label": "__label__POS", "pred_score_pos": 0.9815418720245361}
{"content": "Nampa ID Cosmetic Dentist | Don’t Rush to Brush Are you a diligent brusher who grabs the toothbrush as soon as you finish each snack or meal? While there are significant benefits to regular brushing, hurrying your hygiene might be doing more harm than good. The key lies in understanding the effects different types of food and drinks have on your teeth. The Dangers […]", "pred_label": "__label__POS", "pred_score_pos": 0.9998723268508911}
{"content": "Abstract\nThis paper investigates the mitigation of limit cycle oscillations (LCOs) using optimally designed nonlinear energy sinks (NESs). The study is based on an NES attached to a two-degree-of-freedom airfoil with nonlinear stiffness in pitch and heave. Depending on the nonlinear properties of the airfoil, it can exhibit super- or subcritical LCOs. The design of the NES is based on a stochastic optimization approach, which accounts for various sources of uncertainties, including initial and loading conditions. The optimization approach is also tailored to handle potential discontinuities in the response of the airfoil. The non-smoothness of the response can be either due to subcritical LCOs or due to the activation of the NES. Several stochastic optimization problems with the objective of maximizing the mean reduction of LCOs are presented.\nASJC Scopus subject areas Aerospace Engineering", "pred_label": "__label__POS", "pred_score_pos": 0.8138872385025024}
{"content": "Abstract\nWe studied, over a four-year period, two adolescents with α\n1-antitrypsin (AAT) deficiency who subsequently died from complications of hepatic cirrhosis. Serial pulmonary function studies indicated mild obstructive lung disease involving peripheral airways in both patients. Postmortem histologic and pulmonary morphometric studies indicated mild diffuse airspace and bronchial gland enlargement, and slight dilation of small airways. This airspace enlargement may represent the early stage of lung disease in AAT-deficient subjects and suggests that pulmonary anatomic changes may occur long before the onset of clinically and pathologically significant emphysema. ASJC Scopus subject areas Pulmonary and Respiratory Medicine Critical Care and Intensive Care Medicine Cardiology and Cardiovascular Medicine", "pred_label": "__label__POS", "pred_score_pos": 0.6968765258789062}
{"content": "The\nCBP Network encompasses all past and current students of the Management of Creative Business Processes Master’s program at the Copenhagen Business School. The program is focused on forming the students into skilled managers ready to work within the creative industries and any other industry deploying creative processes.\nThese industries rely and thrive on networks. Therefore, the network facilitates the students’ entry into the Danish labour market and the exchange about creative industries and processes.\nThe CBP NETWORK story\nIn 2010, four students from the\nCBP Program initiated the network. What started as a small student project has now become an official non-profit organization. It is supported by the Copenhagen Business School. The network is now a key asset to the program.\nEach year, the baton is passed to the next generation of CBP students who manage the\nCBP Network, with the support of the program administration and past students. The network’s goals\nThe\nCBP Network is bridging the gap between young professionals and organizations in the creative industries. Our main mission is to strengthen the link between CBP students and alumni as well as creative organizations through our website and various events.\nThe Network plays a role in promoting the\nMaster in Management of Creative Business Processes at the Copenhagen Business School, here in Denmark. We aim to attract talents from diverse backgrounds and interests to foster dialogue and create relationships. This will help to shape them into creative leaders with the necessary skillset, and network, to navigate the complex processes in creative and innovative industries, both on the local and international level.\nThe goal is that the\nCBP Network will bring new opportunities to all members, as well as to create a pool of young talents with a passion for creativity coupled with a deep understanding of the management challenges it brings. Our members are passionate about the arts, design and innovation and understand an organization’s role in enabling and guiding creativity.", "pred_label": "__label__POS", "pred_score_pos": 0.5035717487335205}
{"content": "Update for graduate and professional school students This message is being emailed to all graduate and professional students on August 11, 2020. For any updates, please visit the Student Affairs website.\nDear graduate student community,\nSome of you have reached out with concerns about the current testing, quarantine and isolation procedures shared in a message with our graduate student community last week. We understand that with each decision and its subsequent communication during this time comes an incredible impact on our students and community. We want to acknowledge how challenging it can be to prepare for a new academic year during a pandemic. We are writing to provide clarification on the procedures and best guidance for how to stay as safe as possible during this time.\nThe State of California has recently released it’s guidance for institutions of higher education. These plans are designed to lower the risk of transmission in higher education campus communities. As we mentioned in the previous message, there will be a campus compact outlining all of the university measures on prevention, testing, quarantine, isolation and physical distancing that aligns with state and county guidance. The primary purpose of this email is to help you navigate your current housing transition into the academic year.\nWe understand that for current residents, the arrival of new students is a specific source of concern as we navigate current public health guidance.\nSpecifically, students who are living in multi-bedroom apartments have expressed concern for transmission of the virus in the entry testing period when a new roommate arrives. When moving on to campus, students are expected to follow the testing protocol shared in the August 6th message. To add, new students are asked to complete a Health Check before arriving. As students prepare for new roommates, here are a few key steps that you can take during the entry testing period:\nAvoid close contactwith your new roommate. Specifically, for COVID-19, the U.S. Centers for Disease Control and Prevention (CDC) define a close contact as being within six feet of a person for at least 15 minutes. Wear a maskwhen you are in the common areas of your shared apartment and in the larger apartment building. Stagger useof common area spaces. For example, avoid sharing kitchen utensils and completely clean up the kitchen area after each use during the testing period. Engage in frequent handwashing and surface cleaning Set shared expectations with your roommate.Discuss how you both plan to communicate and engage in all of the public health measures together, including cleaning, physical distancing and mask wearing in the apartment.\nFor students who remain concerned about the transmission of COVID-19 during the entry testing period, we have a limited number of spaces for students to relocate during the entry testing period (up to 7 days). It is our expectation that the person who expresses discomfort with their current situation will be the one who will relocate temporarily. This is available through August 31, 2020 at which point, we will no longer have capacity to provide this option. Please contact the Graduate Life Office staff if you would like to learn more about this option.\nWe welcome your thoughts and concerns\nDuring a time of a global pandemic, we cannot make our campus community completely safe from the virus; however, together, we can make it safer. COVID-19 is challenging all of us, but we will continue to find solutions together. We recognize that some of you will continue to have questions and concerns. Again, here’s where you can share your general concerns. In addition, if you have individual or specific concerns about navigating your needs, please consult with the Graduate Life Office to receive support and/or contact the Office of Accessible Education, should you have specific accommodations to address.\nShirley Everett\nSenior Associate Vice Provost, Residential & Dining Enterprises\nMona Hicks\nSenior Associate Vice Provost and Dean of Students\nDr. James Jacobs\nExecutive Director, Vaden Health Services", "pred_label": "__label__POS", "pred_score_pos": 0.714470386505127}
{"content": "JTO Clin Res Rep. 2020 Nov 12:100124. doi: 10.1016/j.jtocrr.2020.100124. Online ahead of print.\nABSTRACT\nINTRODUCTION: Lung cancer is associated with severe COVID-19 infections. Symptom overlap between COVID-19 and lung cancer may complicate diagnostic evaluation. We aimed to investigate the incidence, symptoms, differential diagnosis, and outcomes of COVID-19 in lung cancer patients.\nMETHODS: To determine an at-risk population for COVID-19, we retrospectively identified lung cancer patients receiving longitudinal care within a single institution in the 12 months (4/1/19 - 3/31/20) immediately preceding the COVID-19 pandemic, including an \"active therapy population\" treated within the last 60 days of this period. Among patients subsequently referred for COVID-19 testing, we compared symptoms, laboratory/radiographic findings, and outcomes of positive versus negative patients.\nRESULTS: Between 4/1/2019-3/31/2020, 696 patients received longitudinal care, including 406 (58%) in the active therapy population. Among 55 patients referred for COVID-19 testing, 24 (44%) were COVID-19 positive, representing a cumulative incidence of 3.4% (longitudinal population) and 1.5% (active therapy population). Compared to COVID-19-negative patients, COVID-19-positive patients were more likely to have a supplemental oxygen requirement (11% vs. 54%, p=0.005) and to have typical COVID-19 pneumonia imaging findings (5 vs. 56%, p=0.001). Otherwise, there were no significant differences in presenting symptoms. Among COVID-negative patients, alternative etiologies included treatment-related toxicity (26%), atypical pneumonia (22%), and disease progression (22%). Sixteen COVID-19-postive patients (67%) required hospitalization, and 7 (29%) died from COVID-related complications.\nCONCLUSIONS: COVID-19 was infrequent in this lung cancer population, but these patients experienced high rates of morbidity and mortality. Oncologists should maintain a low threshold for COVID-19 testing in lung cancer patients presenting with acute symptoms.", "pred_label": "__label__POS", "pred_score_pos": 0.8319879770278931}
{"content": "For Abdul, living with albinism used to mean living in constant fear. Misconceptions about the cause of albinism made him cautious of interacting with others. But Abdul was able to connect with our disability ministry in Malawi. And, thanks to the support of people like you, Abdul was introduced to his Savior and found Christian community.\nSince 2014, reported crimes against Malawians with albinism has risen to 163+ cases including 22 murders.*\nSome Malawians believe the bones of people with albinism hold special powers. Others believe they are liars and can’t be trusted.\nAlbinism is a genetic condition that prevents the body from producing or distributing melanin.\n– Abdul\nWhile albinism doesn’t cause physical disabilities, those with albinism in Malawi face severe discrimination, judgment, and threats from their communities. This is why our disability ministry has made it a point to include them in our work.\nSunscreen is difficult, if not impossible, to find in Malawi, so sunscreen and hats are provided to individuals like little Elena.\nAt the same time, spiritual needs are met by connecting people like Abdul to the Bible and God’s love through direct gospel proclamation and worship opportunities.\nAbdul was raised Muslim, but when he was sent to live with relatives 300 miles away he began practicing Christianity. Then he heard about a church that could supply him with sunscreen. It was there that he connected with the disability ministry.\nThe disability ministry introduced him to people who helped him explore the Bible and answered his questions. His faith began to grow. Now Abdul is not only a program participant with the disability ministry, he is a dedicated volunteer!\n– Abdul\nAbdul volunteers with the disability ministry to help both those with albinism and those with disabilities. “I want people to understand us fully,” Abdul says. “If they understand us fully, it will be easier for them to support us.”\n“I have come that they may have life, and have it to the full.” – John 10:10\nStereotypes and misconceptions surrounding albinism in Malawi instill fear, and separate people like Abdul from the rest of society. This keeps people with albinism from living the lives God created them to live. It keeps them from experiencing the freedom found in Jesus.\nNames and images may have been changed for privacy or security.\n*Amnesty International", "pred_label": "__label__POS", "pred_score_pos": 0.5043613910675049}
{"content": "Institutionalizing Peacebuilding Institutionalizing Peacebuilding\nThe UNCC, Conflict Resources, and the Future of Natural Resources in Transitional Justice\nThis chapter explores the appropriation and exploitation of natural resources during armed conflict and considers the challenges that conflict resources pose to post-conflict peacebuilding. It analyzes legal norms that constitute the international law into shaping how tribunals address conflict resources in the future and examines how the UN Compensation Commission’s (UNCC) approaches may be applied to conflict resources in other peacebuilding and transitional justice bodies. The chapter concludes with formalized institutional frameworks for future responses to conflict resources and wartime environmental harm.\nOxford Scholarship Online requires a subscription or purchase to access the full text of books within the service. Public users can however freely search the site and view the abstracts and keywords for each book and chapter.\nIf you think you should have access to this title, please contact your librarian.", "pred_label": "__label__POS", "pred_score_pos": 0.769270658493042}
{"content": "Macro Notes provide analysis on key macro and geopolitical developments. They complement the existing IIF product line up, which includes Global Macro Views, Economic Views, in depth country reports and data.\nGovernment debt in Sub-Saharan Africa has risen markedly in recent years. This is partly due to issuance of Eurobonds in a low interest rate environment. Debt amortization will peak in 2024-25, while financing needs remain high. As a result, these countries will need to attract significant non-resident capital. Tightening of global financial conditions could increase debt costs substantially.\nSub-Saharan Africa continues to display stronger growth than other EMs. However, this has not resulted in meaningful real convergence for most. Continued high, though declining, population growth is partly responsible. Higher productivity growth is necessary to improve living standards quicker. Rising indebtedness represents the key risk to the medium-term outlook.\nLooser DM monetary policy and the US-China truce drove flows to EM. 2019 saw an important rebound in portfolio flows compared to 2018. Foreign currency and local debt attracted the bulk of non-resident flows. Going forward, foreign investors will likely focus on idiosyncratic stories.\nUkraine’s new agreement with the IMF is critical for external financing, even though recent flows into domestic bonds have alleviated pressure. The agreement signals confidence in ongoing reform efforts to markets, and will lead to renewed investor interest in local government bonds.\nThe release of the 2019 MTBPS was a wake-up call for politicians, just like in 2017. The 2020 budget in February, union negotiations, and Eskom resolution are key. Moody’s is likely to downgrade South Africa’s rating to sub-IG sometime in 2020. A deep domestic market and low short-term and FX debt mitigate our concerns. But with deteriorating debt dynamics, South Africa is exposed to external shocks.\nEU structural funds have boosted growth in Eastern Europe, allowing for strong income convergence with the rest of the EU. Cuts in the 2021-27 EU budget will lead to smaller contributions, but a sudden slowdown is unlikely, and convergence will continue.\nInflation is trending down in many emerging markets. This is partially due to higher central bank credibility. EM inflation has also become increasingly synchronized. Persistently lower inflation could allow for more easing. Risk of reversals and country-specific shocks remains high.\nRussian authorities announced a policy pivot towards growth. National projects exceed 3% of GDP per year over 2019-24. Apart from national projects, policies will likely remain tight. We therefore expect only a modest pickup in Russia’s growth.\nWeak growth has led to deteriorating debt dynamics in recent years. Falling business and consumer confidence do not point to a recovery. External imbalances remain despite weak activity and depreciation. Interest payments to non-residents have risen sharply due to high debt. The Rand is vulnerable to shifts in market sentiment and portfolio flows.\nMarkets were disappointed by the 2019 MTBPS announcement. Revisions to growth, deficit, and debt were worse than expected. This follows an Eskom plan lacking details on debt restructuring. Moody’s changed the outlook to negative but kept the IG rating. Key market concern is no longer the rating, but debt sustainability.", "pred_label": "__label__POS", "pred_score_pos": 0.8035340309143066}
{"content": "The DCYA-led Temporary Wage Subsidy Childcare Scheme (TWSCS) was launched on 15 April as a unique, sector specific response to the COVID-19 crisis. While the scheme was being developed, preliminary payments were paid in advance to providers to enable them to retain their staff and cover some overhead costs. These preliminary payments were primarily based on pre-covid staffing levels. It emerged subsequently that such staffing levels were not maintained by some providers and this has resulted in excess funding.\nA letter was issued to providers by Pobal on 16 September informing of their overpayment status and set out how proposed recoupment of the excess funding will take place.\nThe TWSCS rules made clear the purposes for which this sector specific funding was intended for. Excess funding provided was required to be returned to the Exchequer at the earliest opportunity. Many services will therefore still have the excess amount in their accounts and be in a position to repay it when requested. Some providers have expressed a wish to return the excess funding immediately and structures are in place to facilitate this.\nMy Department, in recognition of pressures the providers are facing in trying to safely reopen have allowed a “grace” period by delaying the recoupment process until November. This will give providers an opportunity to manage their cashflow requirements in the coming weeks.\nMy Department has worked closely with the Department of Public Expenditure and Reform and it is not possible from an Exchequer perspective to extend repayment into another financial year, except of course in exceptional circumstances as discussed below.\nIt is acknowledged that some providers may require special or alternative arrangements due to ongoing cashflow difficulties. My Department is prepared to be flexible in supporting providers who may struggle with recoupment and Pobal will be available to work closely with these providers.\nIf a provider continues to experience ongoing viability issues, my Department has recently launched a new Sustainability Fund. This will assist providers (not-for-profit and for-profit) struggling with an imminent threat to the viability of their service arising from the COVID-19 Pandemic. In the meantime my Department encourages providers seeking further advice and support to contact their City/ County Childcare Committee in the first instance.\nIt is worth noting that in 2020, it is estimated that an additional €180m, above and beyond the childcare budget, will have been invested in the sector. Also, for the first 3 months of 2021 alone, the EWSS will be worth €63m to providers, again on top of their usual Departmental payments. Intensive and very successful efforts have been made by the Department to boost the income of providers in recent years with the 141% increase in investment in the sector. This has enabled services to grow from an average size of 33 places to 47, to access subsidies for twice the number of children as before, to access increased ECCE capitation payments, free CPD for staff, Programme Support Payments worth at least €19m per annum and extra capital investment, for example.\nMy Department remains committed to supporting services to provide accessible, affordable and high quality services to children and families.", "pred_label": "__label__POS", "pred_score_pos": 0.7505760192871094}
{"content": "CardioVit\nA healthy heart is essential for overall wellness and longevity. On average, a healthy human heart beats over 100,000 times per day, 24 hours a day; resting only slightly each night while we sleep. Its primary function is to pump blood throughout the body, and in the process provide the oxygen and nutrients we need to live. Like any hard-working machine, the heart requires a unique combination of attention, respect, and maintenance. Nature’sField\nCardioVit supports cardiovascular health by targeting three key issues that affect heart health ie Cholesterol, Circulation and blood pressure with a single one tablet per day daily dose. CardioVit is an advanced formula of 24 super nutrients that enhance heart health and has been formulated to provide you with enhanced nutritional support to ensure a healthy heart function.\nHeart disease is the leading cause of death worldwide. Guard your heart with a daily dose of Nature’sField\nCardioVit!\nNature'sfield", "pred_label": "__label__POS", "pred_score_pos": 0.8361491560935974}
{"content": "The article 'Protected by pluralism? Grappling with multiple legal frameworks in groundwater governance' written by Ms. Kirstin I. Conti and Prof. Joyeeta Gupta has been published in the scientific journal 'Current Opinion in Environmental Sustainability.' The article is in its special issue on sustainability science - legal pluralism and deals the consequences of legal pluralism for groundwater access, allocation and sustainability. Kirstin Conti is PhD Researcher at IGRAC and Joyeeta Gupta is Professor of Environment and Development in the Global South at the University of Amsterdam (UvA) and UNESCO-IHE. Protected by pluralism? Grappling with multiple legal frameworks in groundwater governance\nNote: The following text is abstracted from the article\n\"Groundwater constitutes approximately 97% of the world's non-frozen freshwater resources. Every country has groundwater and there are 608 transboundary aquifers. Over half of the world's population uses groundwater for its daily needs and over 40% of agriculture is irrigated by groundwater. Groundwater sustains groundwater dependent ecosystems and buffers against climate change and variability. However, groundwater governance is sporadic and disjointed. Therefore, in this article it is examined through the lens of legal pluralism.\nApproach\nCurrent literature is reviewed and norms for groundwater governance are presented at each geographic level along with American, European, Asian and African examples. This is a new exploration of legal pluralism and its consequences for groundwater access, allocation and sustainability. It shows that challenges regarding scope, jurisdiction and application of norms manifest themselves in legal-plural regimes with differing consequences: groundwater degradation and problems of access and allocation on the one hand and improved, coherent governance structures on the other.\"\nHighlights Legal pluralism sometimes contributes to groundwater depletion or user conflicts. In other instances pluralism can lead to improved, coherent governance structures. Scope/jurisdiction issues are often indifferent or accommodating. Sovereignty/access/allocation issues tend to compete. Several norms are supported mutually in formal laws, but sometimes lack enforcement.", "pred_label": "__label__POS", "pred_score_pos": 0.673609733581543}
{"content": "Journal of Cognitive Neuroscience\nVisual perception seems continuous, but recent evidence suggests that the underlying perceptual mechanisms are in fact periodic—particularly visual attention. Because visual attention is closely linked to the preparation of saccadic eye movements, the question arises how periodic attentional processes interact with the preparation and execution of voluntary saccades. In two experiments, human observers made voluntary saccades between two placeholders, monitoring each one for the presentation of a threshold-level target. Detection performance was evaluated as a function of latency with respect to saccade landing. The time course of detection performance revealed oscillations at around 4 Hz both before the saccade at the saccade origin and after the saccade at the saccade destination. Furthermore, oscillations before and after the saccade were in phase, meaning that the saccade did not disrupt or reset the ongoing attentional rhythm. Instead, it seems that voluntary saccades are executed as part of an ongoing attentional rhythm, with the eyes in flight during the troughs of the attentional wave. This finding for the first time demonstrates that periodic attentional mechanisms affect not only perception but also overt motor behavior.", "pred_label": "__label__POS", "pred_score_pos": 0.5163718461990356}
{"content": "Currently, there are no specific treatments recommended for illnesses caused by COVID-19.\nFor most people, the treatment is the same for flu, which includes over the counter cough/cold and fever medicines. However, for people who get sicker, like with pneumonia, treatment in the hospital is to support the patient’s body functions till the patient recovers.", "pred_label": "__label__POS", "pred_score_pos": 0.9975372552871704}
{"content": "A growing trend in the hotel industry is the addition of “market” areas within hotels, where guests can purchase a variety of items, including microwave meals, snacks and beverages. If a hotel wants to sell alcoholic beverages from its market, it must hold a liquor license. New York’s Alcoholic Beverage Control Law does not currently have a mechanism for licensing these “markets,” but there are ways hotels in the state can obtain a liquor license for these areas.\nIf a hotel holds a hotel liquor license, which is common in a full-service hotel, it may apply for an additional bar license to sell alcoholic beverages in its market. In a hotel with a liquor license, guests are permitted to take alcohol to their rooms and other areas of the hotel to consume. Guests, however, cannot leave the hotel with wine or hard liquor purchased in the hotel, although they can take beer off the premises.\nIf a hotel does not hold a liquor license, as is typical in limited-service hotels, it may apply for a liquor license specifically for the market. This type of license requires that the hotel sell food items in the market and provide seating within it or adjoining it. To meet the minimum food requirements, the offerings must be more substantial than chips and crackers, and can include such things as microwave meals, soups, salads and sandwiches. While beer may be taken out of the market area or an adjoining seating area included within the licensed premises, wine and liquor must be consumed in the market/seating area.\nPlease note that the sale of wine and/or spirits in hotel markets has one additional requirement: Hotel employees must “serve” the wine and/or spirits to guests (i.e., uncork the wine or pour/mix spirits).", "pred_label": "__label__POS", "pred_score_pos": 0.7363123297691345}
{"content": "Malaria is among the leading cause of infection in individuals with sickle cell disease (SCD) living in sub-Saharan Africa, including Tanzania. However, after 2005 the standard treatment guidelines (STGs) on malaria chemoprevention for SCD patients were non-existent, and at present no medicine is recommended for SCD patients. Since several anti-malarials have been approved for the treatment of malaria in Tanzania, it is important to establish if there is a continued use of chemoprevention against malaria among SCD children.\nsub-Saharan Africa\nPlasmodium vivax infection is rising in sub-Saharan Africa, where Plasmodium falciparum is responsible for more than 90% of malaria cases. While P. vivax is identified as a major cause of severe and cerebral malaria in South east Asia, the Pacific and South America, most of the severe and cerebral cases in Africa were attributed to P. falciparum. Cases of severe malaria due to P. vivax are emerging in Africa. A few severe P. vivax cases were reported in Eastern Sudan and they were underestimated due to the lack of accurate diagnosis, low parasitaemia and seldom use of rapid diagnostic tests (RDTs).\nNext-generation sequencing (NGS) technologies are increasingly being used to address a diverse range of biological and epidemiological questions.\nParasite resistance against anti-malarial drugs is a major threat to the ongoing malaria control and elimination strategies.\nUnlike the case in Asia and Latin America, Plasmodium vivax infections are rare in sub-Saharan Africa due to the absence of the Duffy blood group antigen (Duffy antigen), the only known erythrocyte receptor for the P. vivax merozoite invasion ligand, Duffy binding protein 1 (DBP1).\nPopulations in sub-Saharan Africa have historically been exposed to intense selection from chronic infection with falciparum malaria.\nMalaria remains a major global threat to human health and economic development.\nWhile the importance of understanding human-vector interaction is well-established, relatively few studies have included human behaviour when measuring exposure to malaria vectors.\nThe present study gave the first molecular evidence of P. vivax in Nigeria in Duffy negative individuals.\nIn sub-Saharan Africa, inherited causes of anemia are common, but data are limited regarding the geographical prevalence and coinheritance of these conditions and their overall contributions to childhood anemia.", "pred_label": "__label__POS", "pred_score_pos": 0.65657639503479}
{"content": "Abstract\nThe difference between transcriptional and translational activities of genes is one of the remarkable features in spermatogenesis. In this study, we characterized MIF4GD (MIF4G domain containing), a possible translational regulator, to uncover the function during rat spermatogenesis. Western blot analysis revealed the presence of two forms of MIF4GD with molecular sizes of 25 and 16 kDa in various tissues including the testis. An additional 20-kDa form of MIF4GD was also found exclusively in the testis. These three proteins were abundantly present in pachytene spermatocytes and haploid spermatids. Importantly, the 16-kDa MIF4GD was distinguished from the 25- and 20-kDa proteins by presence in fractions of 40S subunits and ribosomes of spermatogenic cells according to analysis of subcellular localizations. These results suggest that the 16-kDa MIF4GD may function as a translational regulator in spermiogenesis.\nKeywords Rat Spermatogenesis Translation regulation ASJC Scopus subject areas Animal Science and Zoology", "pred_label": "__label__POS", "pred_score_pos": 0.8777797222137451}
{"content": "The tutorial is intended primarily for beginners, but it will also beneficial to experimentalists who understand electroencephalography and event related techniques, but need additional knowledge in annotation, standardization, long-term storage and publication of data.\nIntroduction to the first phases of EEG/ERP data lifecycle\nEEGLAB is an interactive Matlab toolbox for processing continuous and event-related EEG, MEG and other electrophysiological data incorporating independent component analysis (ICA), time/frequency analysis, artifact rejection, event-related statistics, and several useful modes of visualization of the averaged and single-trial data. EEGLAB runs under Linux, Unix, Windows, and Mac OS X.\nThis lecture focuses on how the immune system can target and attack the nervous system to produce autoimmune responses that may result in diseases such as multiple sclerosis, neuromyelitis and lupus cerebritis manifested by motor, sensory, and cognitive impairments. Despite the fact that the brain is an immune-privileged site, autoreactive lymphocytes producing proinflammatory cytokines can cause active brain inflammation, leading to myelin and axonal loss.\nJupyterHub is a simple, highly extensible, multi-user system for managing per-user Jupyter Notebook servers, designed for research groups or classes. This lecture covers deploying JupyterHub on a single server, as well as deploying with Docker using GitHub for authentication.\nThis talk highlights a set of platform technologies, software, and data collections that close and shorten the feedback cycle in research.", "pred_label": "__label__POS", "pred_score_pos": 0.9661263823509216}
{"content": "Tax revenues in African countries, on average, have remained at the same level during 2018 for the fifth consecutive year, with the ongoing COVID-19 crisis expected to significantly reduce public revenues across the region, according to a new report.\nThe 2020 edition of\nRevenue Statistics in Africa shows that the average tax-to-GDP ratio for the 30 participating countries remained unchanged for the fifth consecutive year, at 16.5%. With countries facing high levels of uncertainty due to the ongoing pandemic, African governments will need to carefully sequence their efforts to secure fiscal space for a strong and inclusive recovery and, once the health and economic crises are under control, mobilise additional domestic revenues to meet longer-term objectives.\nThe report, launched on Thursday during a virtual event, identifies a wide variation between the level and trajectory of public revenues across the 30 participating countries, including Chad, Lesotho, Malawi and Namibia for the first time. Tax-to-GDP ratios ranged from 6.3% in Equatorial Guinea and Nigeria to 32.4% in the Seychelles. The tax-to-GDP ratio exceeded 25% in four countries (Morocco, Seychelles, South Africa and Tunisia) and was less than 10% in five (Chad, the Republic of the Congo, the Democratic Republic of the Congo, Equatorial Guinea and Nigeria).\nBetween 2010 and 2018, the Africa (30) average tax-to-GDP ratio increased by 1.4 percentage points (p.p), with most of the growth occurring between 2010 and 2014. By comparison, the tax-to-GDP ratio in Latin America and the Caribbean (LAC) rose by 1.9 p.p. to 23.1% while the OECD’s average rose by 2.0 p.p. to 34.3% between 2010 and 2018. The report shows how taxes remain the largest source of public revenues in Africa and are typically more stable than non-tax revenues: average non-tax revenues fell from 8.3% to 6.5% of GDP between 2010 and 2018 due to declines in natural resource revenues and grants.\nTaxes on goods and services were the main source of tax revenues among Africa (30) countries, accounting for 51.9% of total tax revenues on average in 2018; value-added tax alone accounted for 29.7% of total tax revenues. Revenues from corporate income tax, which tends to be more volatile than other taxes, are also high in Africa relative to other regions, at 19.2% of total taxation compared to 15.5% and 9.3% in the LAC and OECD areas, respectively. By contrast, social security contributions and personal income taxes are comparatively low in Africa.\nThe report contains a special feature about domestic resource mobilisation during and after the COVID-19 pandemic. This examines the fiscal policy responses of countries to the pandemic and explains the importance of continuing support for households and businesses as fiscal positions allow, ensuring the effectiveness of these measures through appropriate targeting, and of monitoring their impact. It also discusses the potential contribution of the African Continental Free Trade Area (AfCFTA) to the region’s resilience and economic recovery.\nRevenue Statistics in Africa is a joint initiative between the Centre for Tax Policy and Administration of the Organisation for Economic Co-operation and Development (OECD), the OECD Development Centre, the African Tax Administration Forum (ATAF) and the African Union Commission (AUC), with technical support from the African Development Bank (ADB) and the Cercle de Réflexion et d’Échange des Dirigeants des Administrations fiscales (CREDAF). The 2020 edition received financial support from the governments of Ireland, Japan, Luxembourg, Norway, Sweden and the United Kingdom.", "pred_label": "__label__POS", "pred_score_pos": 0.8404904007911682}
{"content": "Overview\nMy research at Cardiff University is focussed on identifying environmental triggers that induce Cyanobacterial production of Geosmin. Geosmin is a naturally occurring metabolite that imparts unpalatable earthy and musty flavours to drinking water, costing the UK water industry over £200 million per annum to treat. Current monitoring of Cyanobacterial Blooms only indicates a proxy for biomass, which doesn’t correlate with the Geosmin release. During my PhD I aim to establish a link between nutrient dynamics and Geosmin synthetase activity within drinking water reservoirs. Allowing a more pre-emptive model to be implemented to prevent future Geosmin problems.\nResearch Thesis Environmental triggers for geosmin production in freshwater ecosystems Funding source\nGW4 FRESH", "pred_label": "__label__POS", "pred_score_pos": 0.9599171280860901}
{"content": "twitter.com/Amgen\nwww.amgen.com\nheadcount: 21,500\nYear Established: 1980\nRevenues: $23,747 (+4%)\nNet Income: $8,394 (NM)\nR&D: $1,182 (+13%)\nTOP SELLING DRUGS\nDrug\nIndication\n2018 Sales\n(+/-%) Enbrel rheumatoid arthritis $5,014 -8% Neulasta chemotherapy induced neutropenia $4,475 -1% Prolia bone cancer $2,291 16% Aranesp chemotherapy induced anemia $1,877 -9% Xgeva bone cancer $1,786 13% Sensipar/Mimpara renal disease $1,774 3% Epogen anemia $1,010 -8% Kyprolis multiple myeloma $968 16% Nplate immune thromboytopenia $717 12% Vectibix colorectal cancer $691 8%\nWhile Amgen’s newer drugs Prolia, Xgeva, Blincyto, Kyprolis continue to drive growth, its mature flagship products are facing rising competition. Sales of Neulasta and Neupogen are declining due to biosimilar competition from several companies, including Mylan and Coherus BioSciences. Several others face generic competition as well, including Enbrel, Aranesp and Epogen. Meanwhile, sales of Amgen’s new migraine drug, Aimvoig, were unimpressive in the first quarter of 2019, and it’s up against strong competition from Lilly’s Emgality and Teva’s Ajovy.\nAmgen is successfully advancing its pipeline with the approval of osteoporosis drug Evenity in April, and Kanjinti, a biosimilar of Roche’s breast cancer drug Herceptin, in June. This is the third biosimilar from Amgen’s portfolio to receive approval, providing the potential for long-term revenues. Amgen expects to launch additional biosimilars in 2019.\nAs part of an effort to bolster its R&D efforts, Amgen recently offered to acquire Nuevolution, a drug discovery platform biotech company based in Denmark, for approximately $167 million. The Nuevolution board has recommended accepting the offer and Amgen expects to settle by July 15. The two companies have collaborated since October 2016 for drugs targeting multiple indications including two cancer programs. Having Nuevolution’s discovery platform in-house may aid Amgen’s discovery efforts for small molecules against difficult-to-drug targets and make the process more efficient.\nAdditionally, to further enhance its manufacturing capabilities, Amgen is expanding its campus in West Greenwich, RI with a new $160 million next-gen biomanufacturing plant that will be the first of its kind in the U.S. It will manufacture products for the U.S. and global markets. Amgen plans to incorporate multiple innovative technologies into a single facility, which is expected to be built in half the construction time with approximately half of the operating cost required of a traditional plant. Next generation biomanufacturing plants require a smaller manufacturing footprint offering environmental benefits such as reduced water and energy consumption, and lower levels of carbon emissions.\nAmong its more significant approvals, Amgen and UCB gained FDA approval for EVENITY for the treatment of osteoporosis in postmenopausal women at high risk for fracture. EVENITY is the first and only bone builder with a unique dual effect that both increases bone formation and to a lesser extent reduces bone resorption (or bone loss) to rapidly reduce the risk of fracture.\nIn October, the FDA approved the expanded indication for KYPROLIS to include a once-weekly dosing option in combination with dexamethasone for patients with relapsed or refractory multiple myeloma. The approval was based on Phase III data demonstrating that KYPROLIS achieved superior progression-free survival and overall response rates, with a comparable safety profile, versus twice-weekly. The FDA reviewed the application under its Real-Time Oncology Review and Assessment Aid pilot programs, which aim to explore a more efficient review process to ensure that safe and effective treatments are available to patients as early as possible.\nAlso, Amgen’s BLINCYTO gained approval for relapsed or refractory B-cell acute lymphoblastic leukemia (ALL) in Japan, and an expanded indication as a monotherapy to include adult patients with Philadelphia chromosome negative (Ph-) CD19 positive B-cell precursor acute lymphoblastic leukemia (ALL) by the European Commission. Developed by a joint venture between Amgen and Astellas Pharma Inc., BLINCYTO is the first-and-only bispecific T cell engager (BiTE) immunotherapy construct approved globally. It’s also the first approved immunotherapy from Amgen’s BiTE platform, an approach that helps the body’s immune system target cancer cells.\nAmgen and its biosimilar partner Allergan, recently received approval from the FDA for Kanjinti, a biosimilar of Roche’s breast cancer drug, Herceptin, for all approved indications of the reference product, HER2 adjuvant and metastatic breast cancer, and HER2 metastatic gastric cancer or gastroesophageal junction adenocarcinoma. Since December of last year, the FDA approved four biosimilar versions of Herceptin including Kanjinti: Pfizer’s Trazimera, Merck/Samsung Bioepis’ Ontruzant, and Celltrion/Teva’s Herzuma).\nKanjinti is the third biosimilar from Amgen’s portfolio to receive approval in the U.S. and Europe, joining Amjevita (a biosimilar of Abbvie’s Humira) and Mvasi (a biosimilar of Roche’s cancer drug Avastin). Currently, Amgen has 10 biosimilar products in its portfolio and a biosimilar version of Johnson & Johnson/Merck’s Remicade (ABP 710) is under review in the U.S. and EU.\nThe collaboration with Allergan includes the development and commercialization of four oncology antibody biosimilars. A biosimilar version of Roche’s Rituxan is in late-stage development for non-Hodgkin’s lymphoma and rheumatoid arthritis.\nInnovative oncology efforts are advancing as well. Amgen recently reported early data from a Phase I trial of AMG 510 showing promising activity in a study of 35 patients targeting one of the most commonly mutated genes in cancer. Analysts are suggesting it has the potential to be the next cancer blockbuster. Out of 10 lung cancer patients receiving Amgen’s AMG 510 in the early-stage study, five went into partial remission and another four saw their disease stabilize. One patient experienced a complete remission four months after treatment. Representing a 90% disease control rate which is quite remarkable for a Phase I trial.\nMG 510 targets KRAS G12c mutation, which accounts for about 13% of non-small cell lung cancers and 3% to 5% of colorectal cancers, and has been the subject of research for decades. While Amgen’s results in colon cancer were less robust, it’s still too early to tell.\nFurthermore, several interesting early research collaborations are underway. Most recently, a collaboration with Intermountain Health aims to rapidly develop new medicines. Amgen’s subsidiary deCODE genetics will have access to the genomes of 500,000 participants from a study carried out by Intermountain Healthcare. Amgen hopes to use this data to uncover new insights into specific diseases and develop new medicines that reach the right disease targets. The collaboration aims to improve success rates and reduce drug development cycle times. To date, Amgen has accelerated the development timeline from early preclinical work through clinical development with several of its molecules, including AMG 510, currently in Phase I.\nIn October, Amgen made an equity investment of $66 million in Oxford Nanopore Technologies, a UK-based company advancing a new generation of portable genetic sequencing technology to perform direct, real-time sequencing of DNA and RNA. deCODE Genetics uses Oxford’s sequencing technologies to conduct genome research, including the identification and validation of new targets. The investment aligns with Amgen’s strategic focus on using human genetics to develop new medicines.", "pred_label": "__label__POS", "pred_score_pos": 0.7013339996337891}
{"content": "When smart care management teams and coaching are actively linked in the clinical setting, improved outcomes result. The COVID-19 pandemic has changed the culture of many practices, disrupted earlier adopted workflows and often created different contexts for coaching engagement. Yet, the intent and commitment to quality care remain top priority for virtually every practice.\nThe Clinical Health Coach partnered with HealthTeamWorks to offer a care management practice improvement webinar to address key issues facing many teams in clinical settings. In this webinar the seasoned HealthTeamWorks faculty, Diane Cardwell, MPA, NP, PA-C and will engage your interest and guide your exploration around the key objectives detailed below.\nLearning Objectives", "pred_label": "__label__POS", "pred_score_pos": 0.9171573519706726}
{"content": "Plant Pono, an environmental agency working with local farmers, aims to curb the spread of invasive plants and support native Hawaiian plants.\nPlant Pono is an environmental agency working with local farmers to regulate the distribution of Hawaiian plants. The Big Island Invasive Species Committee (BIISC) oversees the Plant Pono program on the Big Island. BIISC and Plant Pono endorse companies that promote sustainable landscaping to prevent the spread of invasive species. Many believe that the distribution of invasive species such as Coqui Frogs and Fire Ants is accelerated by invasive plants.\nWaimea grower\nKari Hagerman of Pomaikai Plant Company has developed a two-step process to address this issue:\nFirst, they (plants) are quarantined and tested for ants and frogs in Hilo before they are put on the truck. Then after they are delivered to the nursery in Waimea, they are quarantined and tested again.\nThe Pomaikai Plant Company refuses to market any of their produce until it has been officially declared pest-free.\nOther Plant Pono farmers prevent the spread of invasive species on an individual scale. Farmers market vendor\nMichael Gibson of Elemental Foods always carries peanut butter with him to use as bait for invasive Fire Ants on his plants. All Plant Pono farmers are deeply committed to the Plant Pono initiative and prove that any contribution, no matter how small, is important in preventing the spread of invasive species. Brad Belmarez of Aikane Nursery acknowledges the destructive capacity of invasive species and the ecological benefits of native Hawaiian plants. Belmarez encourages the use of native plants in local Hawaiian landscape and works with his customers to identify suitable plants for specific environments. Belmarez comments:\nMost people don’t know much about native plants, or how well adapted they are to our local conditions.\nBelmarez and other Plant Pono farmers recognize the adaptive advantages native plants have over other species. Selecting a Hawaiian plant positively contributes to the overall health of the natural environment by ensuring that limited natural resources are utilized by native plants and not exploited by invasive species. Some farmers like Michael Gibson recognize the integral role native plants play in establishing a relationship between people and the land. By supporting Hawaiians in reconnecting with the land, Plant Pono is creating a more sustainable future for Hawaii.\nPlant Pono has also created public platforms so that Hawaiians can individually contribute to invasive species prevention. BIISC and Plant Pono have compiled a list of over 775 invasive plants to avoid planting, including New Zealand flax, Mexican Flame Vine, Night Blooming Jasmine, and the Australian Tree Fern. Plant Pono has also developed the Hawaii Pacific Weed Risk Assessment, a screening process that calculates the potential risk of introduced and invasive species. If a plant scores a 6 or higher it is considered a threatening species.\nPrograms such as Plant Pono show that working taking action within small communities to mitigate invasive species impacts can truly make a meaningful difference.\nNew Research Points the Way for Invasive Species Management - August 8, 2017 Seed Bank in Hawai’i Protects Native Plants - July 28, 2017 Sydney Welcomes Back the Brown Antechinus - July 18, 2017 Little Spotted Kiwis To Return Home - July 13, 2017 Big Island Recruited for Long-term Climate Change Research - July 6, 2017 Hawai’i Community Responds to Little Fire Ants - July 6, 2017 North Brother Island: Small but Significant - June 30, 2017 The Snake Curtain: Cuban Boa Demonstrates Cooperative Hunting - June 28, 2017 Protecting the Endangered Northern Brown Kiwi - June 9, 2017 Sticky: Rediscovering the Lord Howe Stick Insect - June 5, 2017", "pred_label": "__label__POS", "pred_score_pos": 0.7450802326202393}
{"content": "As far as energy-efficient HVAC installation in Columbia, there’s great news for your family at tax time.\nThe Residential Energy Efficient Property Credit has been extended through 2020. This can qualify you for incentives for energy-efficient home enhancements, like modern heating and cooling equipment, water heaters and heat pumps.\nWhat Are the Eligibility Requirements?\nTo qualify for the reduction, the house must be the taxpayer’s main residence in the USA. The improvement must have a life of at least five years, with the first use originating with the taxpayer.\nWhat Kinds of Changes are Regarded as High-Efficiency Upgrades?\nTypically, this tax reduction is equivalent to 10% of the expense of the following energy-saving changes that achieve specific ENERGY STAR® requirements:\nAdvanced main air-circulating fans Energy-efficient gas, propane or oil furnaces Energy-efficient gas, propane or oil hot water boilers Energy-efficient heat pumps Energy-efficient water heaters Energy-efficient central air conditioners Insulation Particular metal and asphalt roofing Particular exterior storm windows, skylights and storm doors Solar/geothermal energy products, for instance solar electricity, solar water heaters and geothermal heat pumps Am I Limited to Claiming a Certain Amount?\nYes, there’s a lifetime limitation of $500 per home. This means if you have claimed this credit in previous years, you should lower any credit you claimed earlier.\nIf you’ve already claimed the maximum amount, you won’t qualify for any additional incentives through this expansion.\nCredit Caps for Certain Items\nCredits have a limit for a couple of participating equipment:\nWindows and skylights—$200 Advanced main air circulation—$50 Hot water boilers—$150 Energy-efficient equipment—$300\nIf you have questions about how you can benefit from the extension of the residential energy efficient property tax credit, download Form 5695 or contact your tax advisor for assistance.\nUpgrade Your Heating and Cooling System Today\nBeen procrastinating upgrading your heating and cooling equipment? Reach the Experts at 803-399-7208 or contact us online. We can help you find an energy-efficient system you can earn tax benefits from the following year.", "pred_label": "__label__POS", "pred_score_pos": 0.5420001745223999}
{"content": "For a more trauma-informed system of care, juvenile courts and their judges are asked to understand the myriad of underlying factors that affect the lives of juveniles and their families. One of the most pervasive of these factors is exposure to trauma. To be most effective in achieving its mission, the juvenile court must both understand the role of traumatic exposure in the lives of children and engage resources and interventions that address child traumatic stress. This questionnaire is designed to determine your Adverse Childhood Experience (ACE) Score, originally adapted from a training with the National Child Traumatic Stress Network (NCTSN). For reprint permissions, visit CDC-Kaiser Study.", "pred_label": "__label__POS", "pred_score_pos": 0.9768654704093933}
{"content": "Flixotide Inhaler (Generic name: fluticasone; alternative brand-name: Flovent ) is prescribed for the prevention of asthma attacks. In a class of drugs called corticosteroids, Flixotide controls symptoms, such as wheezing or a night-time cough.\nLike Flovent, this drug works by reducing inflammation and irritation in air passages, which results in easier breathing. You can save money on Flixotide using PharmacyChecker-accredited online pharmacies. Packaging of Flixotide shows that it is manufactured in Spain and New Zealand.\nThe total price includes shipping fees which typically cover an entire order, making it more economical to purchase multiple medications in the same order.\nU.S. government officials have stated that individuals who order non-controlled prescription drugs from Canada or other foreign sources (up to a three-month supply) for their own use are not being pursued or prosecuted - although it is technically not legal for individuals to import most prescription drugs. The U.S FDA regulates the safety and efficacy of medications sold in U.S. pharmacies. Medications dispensed from outside the U.S. are regulated for safety and efficacy by pharmaceutical/pharmacy regulatory authorities in other countries. Read how regulations may differ by country.", "pred_label": "__label__POS", "pred_score_pos": 0.8698227405548096}
{"content": "This research was conducted to exploit the waste of used plant parts from the widely marketed moth orchid cultivar (Phalaenopsis Sogo Yukidian “V3”). Various extracts of roots, stems, and leaves were evaluated for total phenolics, total flavonoids, and antioxidant capacity. The bound extract from stems contained the highest total phenolics (5.092 ± 0.739 mg GAE (gallic acid equivalent)/g DW (dry weight)). The maximum total flavonoids (2.218 ± 0.021 mg RE (rutin equivalent)/g DW) were found in the hexane extract of leaves. Ethyl acetate extract from roots showed the greatest antioxidant activity compared to other extracts. Of these extracts, the IC50 values of these samples were 0.070 mg/mL, and 0.450 mg/mL in a free radical 1,-diphenyl-picryl-hydrazyl (DPPH) assay and reducing power method, respectively. The lipid peroxidation inhibition (LPI) was found to be 94.2% using the β-carotene bleaching method. Five phenolic compounds including caffeic acid, syringic acid, vanillin, ellagic acid, and cinnamic acid were quantified by high performance liquid chromatography (HPLC). It is suggested that the roots of the hybrid Phalaenopsis Sogo Yukidian “V3” cultivar may be exploited as an effective source of antioxidants.", "pred_label": "__label__POS", "pred_score_pos": 0.567083477973938}
{"content": "Personal Injury Lawyer\nThere is a common issue among accident victims in that many underestimate the value of their potential claim. People often feel that either their injuries are not substantial enough to warrant a lawsuit or that an accident should not merit legal recourse. While the emotions stemming from injuries and trauma are understandable, it is necessary to look at the practical costs of sustained injuries before writing off a potential lawsuit.\nThe Cost of Empathy\nWhile it is natural to feel for the at-fault driver, especially after an accident, you must acknowledge your needs above empathy. It is not uncommon for medical bills and property repairs to reach thousands of dollars in damages. It is also common for sustained injuries to interfere with employment and your ability to make a living. You may not want to sue the at-fault party, but you need to understand that your options to recover financially after an accident may be limited, which leaves little option available for recourse. If you choose to side with empathy, you risk burying yourself in debt.\nCalculating Damages\nTo file a lawsuit, you need to place a value on your injuries, which is not always straightforward. It helps to consider damages in terms of being able to prove them in court. For example, compensatory damages are injuries with a significant paper trail. You should have no issue documenting medical expenses or property repairs stemming from the accident.\nDo not forget to include lost wages in your estimation of damages. Many accident victims are forced to remain out of work until after recovery, and some may need to find a new occupation if injuries lead to a permanent disability.\nWhile many injuries are easy to prove, you should also consider the less provable damages, like pain and suffering. Many jurisdictions allow you to seek compensation for psychological trauma, but because of the discrete nature of the injuries, you will probably need expert testimony from a psychologist or psychiatrist.\nHow an Attorney Can Help\nYou are not alone when figuring out the value of your claim. A personal injury attorney can help you organize your losses and injuries to calculate a fair starting point for negotiations with opposing counsel.\nWhen considering a lawsuit after an accident, do not let empathy or emotion drive the decision. Look at your situation practically, and hire a lawyer, like a personal injury lawyer from Hickey & Turim, to help you calculate the value of your claim.", "pred_label": "__label__POS", "pred_score_pos": 0.9259843826293945}
{"content": "Document Type\nHonors Project\nAbstract\nThis study aimed to examine a potential linguistic cue that signals a speaker's sexual orientation. I examined the relationship between vowel duration and perceived sexual orientation for male speakers of American English. Speakers recorded a passage that was heard by naive listeners and ranked according to perceived sexual orientation. There was no significant difference in vowel duration between men perceived to sound gay and men perceived to sound straight. However, the gay-sounding men produced their diphthongs with more variance in duration than did the straight-sounding men.\nRecommended Citation\nPanfili, Laura, \"Vowel Duration and Perceptions of the Gay Accent\" (2011).\nLinguistics Honors Projects. 7. https://digitalcommons.macalester.edu/ling_honors/7\n©\nCopyright is owned by author of this document", "pred_label": "__label__POS", "pred_score_pos": 0.9241262078285217}
{"content": "DATE: June 16, 2015PARTIES: University of Toronto v. F.A. Panel Members: Ms. Sarah Kraicer, Chair Professor Michael Evans, Faculty Panel Member Ms. Lucy Chau, Student Panel Member Appearances: Ms. Tina Lie, Assistant Discipline Counsel, Paliare Roland, Barristers Dr. Robin Marushia, Instructor for BIOA02H3: Life on Earth: Form, Function and Interactions, University of Toronto Scarborough In Attendance: Professor Wayne Dowler, Dean’s Designate, University of Toronto Scarborough Ms. Natalie Ramtahal, Coordinator, Appeals, Discipline and Faculty Grievances Not in Attendance: The Student Trial Division – s. B.i.1(d) of Code – plagiarism – Student knowingly represented the ideas or expressions of another as her own in a formal lab report submitted for academic credit –Student did not attend hearing – reasonable notice of hearing provided – finding of guilt – no mitigating factors – no engagement in the discipline process – Tribunal sanctions should be reviewed for consistency with other Tribunal sanctions but not with divisional level sanctions – University not required to show how Student committed offence (whether Student plagiarized work of other student or vice versa); in either case, offence is committed and same sanctions apply - sanction for plagiarism must serve as effective deterrent - grade of zero; two year suspension from date of order; corresponding notation on Student’s academic record and transcript for three year period from date of order; and publication by Provost of notice of decision and sanctions with the Student’s name withheld.\nThe Student was charged with one count of academic misconduct under the\nCode of Behaviour on Academic Matters, 1995 (the “ Code”) on the basis that she knowingly committed plagiarism in submitting a formal lab report for academic credit containing the ideas or the expressions of another as her own work. Specifically, the Student was charged with plagiarism under s. B.i.1(d) of the Code. In the alternative, the Student was charged with obtaining unauthorized assistance in connection with the formal lab report under section B.i.1(b) of the Code and with academic dishonesty under s. B.i.3(b) of the Code.\nNeither the Student nor a legal representative of the Student appeared at the hearing. The Panel noted that the onus of proof is on the University under the\nStatutory Powers Procedure Act (the “ Act”) and the University Tribunal Rules of Practice and Procedure (the “ Rules”) to establish that it provided the Student with reasonable notice of the hearing. The Panel heard evidence of the efforts made by the University to serve the Student with notice. It noted that the University provided notice to the Student by both courier and email to the Student’s ROSI mailing address and email account respectively. The Panel also noted the numerous efforts to communicate with the Student by email and by phone at the number provided by the Student. The Panel noted in particular that the University spoke by telephone to a person identifying herself as the Student’s mother who informed the University that she (the mother) had provided the Student with notice of the hearing. In addition, none of the emails sent to the Student bounced back and none of the courier packages were returned. No response was received from the Student. The Panel was satisfied that the totality of attempts made to provide notice to the Student demonstrated that notice had been adequately provided to the Student in accordance with the requirements of the Act and the Rules. As such, the Panel decided to proceed with the hearing in the Student’s absence.\nThe Panel noted the evidence of the coordinator of the course in which the Student was enrolled, who had responsibility for oversight of the course including marks management. The lab report submitted by the Student in this case was submitted via the website Turnitin.com (“Turnitin”), which is used for the detection of possible plagiarism. Turnitin in this case indicated a ‘similarity index’ of 68% between the report submitted by the Student and a report submitted by another student in the same course. As a result, the course coordinator examined the two reports and determined that there were significant similarities between the two. This was despite the fact that the two students were in different groups and not working from the same data set. The Panel noted that three of the five written pages of the Student’s report contained the identical verbatim text as that in the other student’s report and that the remaining two pages contained approximately 50% of the same text. The course coordinator twice requested a meeting with the Student to discuss the report but received no response.\nThe Panel stated that the onus was on the University to establish on clear and convincing evidence on a standard of probabilities that the academic offence charged had been committed. It agreed with the University’s submission that it was not required to show how the Student committed the offence (whether she plagiarized the work of the other student or assisted the other student in plagiarizing her work); in either case, the offence was committed and the same sanctions apply. The Tribunal determined that the evidence was cogent and compelling and established that the report submitted by the Student contained ideas or expressions of ideas that were not her own. The Tribunal found the Student guilty of plagiarism, contrary to s. B.i.1(d) of the\nCode. The remaining charges were withdrawn by the University.\nIn determining the appropriate sanction, the Panel noted the principles set out in\nUniversity of Toronto v Mr. C (Case No. 1976/77-3; November 5, 1976) and noted the importance of consistency in the approach of the Tribunal to sanctions. Although the Tribunal did not consider itself bound by the ‘general standard’ argued for by the University of a two-year suspension in first cases of plagiarism, it did consider the sanctions proposed by the University to be appropriate and reasonable in the circumstances of this case. While there was limited evidence that the Student had received a zero grade on a lab report previously in a different course, the Tribunal accepted the University’s clarification that this case was considered to be a first offence. In this case, the Student did not respond to any communications from the University on this issue, did not attend the hearing and as a result, there were no mitigating circumstances for consideration. The Tribunal noted the seriousness of the offence of plagiarism, stating that this offence strikes at the heart of the integrity of academic work and undermines the essential relationship of trust, learning and teaching between all students and the University. The Tribunal stated that the grave threat that plagiarism poses to the core of academic integrity warrants a strong penalty and must serve as an effective deterrent. The seriousness in this case was somewhat lessened by the fact that the mark value of the plagiarized assignment was worth only 8% of the total course work.\nThe Tribunal did not consider the lighter sanction administered to the other student at divisional level for his similar plagiarism to be a relevant factor in determining the sanction for the Student in the instant case. It noted that the Student in this case failed to participate at any stage of the process. The Tribunal also stated that Tribunal sanctions should be reviewed for consistency with other Tribunal sanctions, and not with divisional level sanctions. The Tribunal imposed the following sanctions: a final grade of zero; a suspension from the University for a period of two years from the date of the order in this case, ending on April 12, 2017; and a notation of the sanction on the Student’s academic record and transcript from the date of the order, ending on April 12, 2018. The Tribunal also ordered that the case be reported to the Provost for publication of a notice of the decision and the sanctions imposed, with the name of the Student withheld.", "pred_label": "__label__POS", "pred_score_pos": 0.5432401299476624}
{"content": "The taxi stand at Nassau St and Witherspoon St in downtown Princeton, which has existed for many years, is set to disappear. As part of their meeting on October 19, Princeton Council agreed to reconfigure the space as parking for downtown businesses.\nThe move was triggered by a proposal from Princeton University to relocate the adjacent bus stop to a site across from South Tulane Street. The bus stop serves north-bound passengers on Suburban Transit/Coach USA commuter buses to New York City, and the NJ Transit 606 bus route. After the bus stop is relocated, a proper bus shelter will be added, along with parking for bicycles. The Princeton Traffic Safety Committee has supported the proposed relocation of the bus stop, because they believe it will help reduce congestion at the intersection of Nassau and Witherspoon St.\nWith the bus stop moved from the intersection of Nassau and Witherspoon St, only taxicabs would be left standing at the existing site. It turns out that the taxi stand doesn’t get that much business. In a three-hour period, municipal staff only observed one passenger pick up a cab at the Nassau Street taxi stand. The number of licensed cabs registered in Princeton has also dropped significantly in recent years. Whereas 28 cabs were licensed in 2018, that number had halved by 2019, and has further dropped to just 5 in 2020. It seems that Princeton cab users are more frequently using services such as Uber and Lyft nowadays, and when they do need a cab ride, they call for the car to come to their location, instead of using the taxi stand on Nassau Street.\nCouncil has therefore decided that the taxi stand should be eliminated, and the space used for metered parking instead. The stand is expected to disappear by April 15, 2021 Licensed cabs can still pick up passengers at the taxi stand at Princeton rail station.", "pred_label": "__label__POS", "pred_score_pos": 0.86553955078125}
{"content": "SimplyVital Health (SVH), a provider of decentralized, secure data access across the healthcare continuum, recently announced the launch of a crucial tool for driving trust and value: Aletheia, a blockchain-based event-logging API that increases trust between data-sharing partners.\nSVH’s decentralized tools, such as Aletheia, are the product of industry-driven demands for transparency between healthcare organizations that need to share critical patient data in the growing value-based care environment.\nAletheia\nAletheia allows developers to leverage blockchain characteristics to build trust within processes by storing application events on public blockchains.\nUsing smart contracts, the API stores cryptographic hashes along with meta-data to provide an immutable history of application events, including the state of complete data objects. This enables an audit-able trail of data access and changes using public immutable blockchains such as Ethereum and SVH’s Nexus.\n“Aletheia is versatile. We’re using it in our own platform to help providers with MIPS requirements. The immutability aids with security and compliance in healthcare.” – Lucas Hendren, CTO of SVH\nDevelopers can access the Aletheia API now online.", "pred_label": "__label__POS", "pred_score_pos": 0.9960488080978394}
{"content": "Robotic stroke rehabilitation therapy can greatly increase the efficiency of therapy delivery. However, when left unsupervised, users often compensate for limitations in affected muscles and joints by recruiting unaffected muscles and joints, leading to undesirable rehabilitation outcomes. This paper aims to develop a computer vision system that augments robotic stroke rehabilitation therapy by automatically detecting such compensatory motions. Nine stroke survivors and ten healthy adults participated in this study. All participants completed scripted motions using a table-top rehabilitation robot. The healthy participants also simulated three types of compensatory motions. The 3-D trajectories of upper body joint positions tracked over time were used for multiclass classification of postures. A support vector machine (SVM) classifier detected lean-forward compensation from healthy participants with excellent accuracy (AUC = 0.98, F1 = 0.82), followed by trunk-rotation compensation (AUC = 0.77, F1 = 0.57). Shoulder-elevation compensation was not well detected (AUC = 0.66, F1 = 0.07). A recurrent neural network (RNN) classifier, which encodes the temporal dependency of video frames, obtained similar results. In contrast, F1-scores in stroke survivors were low for all three compensations while using RNN: lean-forward compensation (AUC = 0.77, F1 = 0.17), trunk-rotation compensation (AUC = 0.81, F1 = 0.27), and shoulder-elevation compensation (AUC = 0.27, F1 = 0.07). The result was similar while using SVM. To improve detection accuracy for stroke survivors, future work should focus on predefining the range of motion, direct camera placement, delivering exercise intensity tantamount to that of real stroke therapies, adjusting seat height, and recording full therapy sessions.\nSign-in or become an IEEE member to discover the full contents of the paper.", "pred_label": "__label__POS", "pred_score_pos": 0.9470056295394897}
{"content": "Boston, MA - Researchers have identified a new regulatory pathway that may play an important role in basal-like breast cancer (BLBC), a particularly aggressive form of breast cancer often referred to as \"triple negative.\" This pathway may serve as a target for the development of an effective therapeutic.\nThese findings appear in the journal\nMolecular Cancer Research.\nWhile targeted cancer drugs are an option for some types of breast cancer, BLBCs are generally unresponsive. Additionally, these tumors tend to metastasize rapidly and patients with this disease generally have a worse clinical prognosis. The aggressive nature of this subtype of breast cancer may be due to the fact that these tumors often harbor a higher content of cancer stem cells (CSCs). CSCs are thought to drive tumor recurrence, progression, metastasis and drug resistance.\nResearchers at Boston University School of Medicine (BUSM), under the direction of Sam Thiagalingam, PhD, found that a protein secreted by BLBC cells, called periostin (POSTN), acted to nurture and support cancer stem cells by activating a distinct signaling pathway in these cells. The researchers found that POSTN acted through a specific integrin receptor that was present on the surface of many BLBC cells. When they disrupted either POSTN or the integrin receptor, they found a dramatic loss of CSCs and an impaired ability of the cancer cells to form tumors.\nThe group also found that BLBCs with high POSTN levels were associated with an increase of key cytokines. \"These findings suggest that BLBC cells have an innate ability to establish a local microenvironment that is supportive of cancer stem cells,\" explained Thiagalingam, associate professor in Genetics & Genomics, Medicine, and Pathology & Laboratory Medicine, at BUSM.\nHe noted that the cases of BLBCs with high POSTN levels were associated with a worse clinical prognosis. \"This indicates that POSTN might be clinically relevant, as a biomarker and or a therapeutic target, in the setting of BLBC.\"\nAt this time however, the potential of using this strategy in patients with BLBC, and possibly some other carcinomas, remains to be evaluated. \"Ultimately, eliminating cancer stem cells may represent a viable approach to combating BLBCs and inhibition of POSTN signaling may be one way to achieve this,\" added Thiagalingam.\n###\nArthur W. Lambert, Ph.D., the lead author of the paper, was a graduate student at BUSM in the Molecular Medicine Program and was supported by a fellowship from the Department of Defense, Breast Cancer Research Program (W81XWH-11-1-0060). Additional support for this research was provided by the Boston University Clinical and Translational Science Institute, the Susan G. Komen for the Cure Foundation and the National Institutes of Health.", "pred_label": "__label__POS", "pred_score_pos": 0.7023133039474487}
{"content": "1 highly unsaturated fatty acids (118 times) Biochemistry (37 times) PUFA (19 times) DHA (18 times) EPA (12 times) 1984 [Effect of different combinations of exogenous higher fatty acids on cardiac function during coronary ischemia and reperfusion]. 2 highly unsaturated FA (12 times) Biochemistry (4 times) FA (7 times) PUFA (3 times) AA (2 times) 2001 The composition of saturated fatty acids in plasma phospholipids changes in a way to counteract changes in the mean melting point during pregnancy. 3 Hospital Universitario Fundacion Alcorcon (2 times) Psychiatry (2 times) --- 2018 [Inverse correlation between psychotic disorders and tumor development]. 4 high-fat diet rich in unsaturated fatty acids (1 time) Nutritional Sciences (1 time) FVII (1 time) FVIIc (1 time) PC (1 time) 2003 Effects of dietary fat quantity and composition on fasting and postprandial levels of coagulation factor VII and serum choline-containing phospholipids. 5 Highly unsaturated fatty acids of the omega-3 series (1 time) Biology (1 time) DM (1 time) EPA (1 time) 2019 Ocean warming combined with lower omega-3 nutritional availability impairs the cardio-respiratory function of a marine fish. 6 HUFA without vitamins (1 time) Zoology (1 time) --- 2010 Physiological characteristics and stress resistance of great sturgeon (Huso huso) juveniles fed with vitamins C, E, and HUFA-enriched Artemia urmiana nauplii.", "pred_label": "__label__POS", "pred_score_pos": 0.632332444190979}
{"content": "Prescription of foot orthoses\nIn some selected cases, an insole or orthosis can be a relief from pain, especially for those with a delicate plantar skin constitution. They also may provide a strong mechanical support in some muscular deficiencies.\nAll diabetics should, in our opinion, use them once the diagnosis is certain since plantar orthoses avoid peak loads occurring at the plant of the foot.", "pred_label": "__label__POS", "pred_score_pos": 0.8640503883361816}
{"content": "Discover how history can be traced through dance.\nTake a fascinating journey to see history in an unique light – through the pastime which invigorated the lives of our ancestors and was a key social activity.\nThis collection reveals the history of dance in early colonial Australia 1770-1850 by exploring significant social and historical links.\nOur history can be brought to life in a unique way by experiencing music and dance – a living link to our heritage.\nIn the modern age of intense electronic social networking, these dances shine as genuine, warm, social pleasures. Words are unnecessary while dancing; other skills are required – a smile, a glance, a touch. Could it be more different to social media on your smart phone?\nIn an evening of country dance one may have a dozen partners and dance with every person in the room; a group of individuals synchronised in the pattern of the dance.\nDance rates as one of the most beneficial forms of recreation: it involves so many different aspects in such an enjoyable way. The\nexercise of moving through the dance, remembering the figures, listening and responding to the music, and above all, the myriad of friendly interactions.\n______________________________________________________________\nThe information on this website www.colonialdance.com.au may be copied for personal use only, and must be acknowledged as from this website. It may not be reproduced for publication without prior permission from Heather Clarke.\n______________________________________________________________\nThis resource was created on the lands of the Gubbi Gubbi people. We pay our respects to their elders past and present. Sovereignty was never ceded.", "pred_label": "__label__POS", "pred_score_pos": 0.7023928165435791}
{"content": "David Webber\n(757) 547-9100\ndavid.webber@lpl.com\nKnowledge is power. It’s also the foundation for intelligent, well-considered decisions. When you have retirement in sight, informed decisions are vital in helping you pursue your goals and avoid costly mistakes that can potentially affect your future.\nAs a financial professional, I am committed to helping people create solutions for their investment assets. Once I understand your risk tolerance, time horizon and goals, I’ll work diligently to develop a program designed with the objective, to carefully balance investment strategies with preserving principal.\nToday’s economic environment brings challenges. But along with challenges come opportunities and potential rewards. I work closely with my clients to evaluate those opportunities and get in position to potentially realize those rewards. I enjoy helping people strive to build a solid financial foundation for the future.\nI invite you to check out all the material on my website. If something prompts a question, please send me a quick email or call my office. I would enjoy speaking with you.", "pred_label": "__label__POS", "pred_score_pos": 0.5090130567550659}
{"content": "Fonte: Journal of Sports Medicine and Physical Fitness, in press, 2020.\nIntroduction: The purpose of this systematic review was to analyze the effect of plyometric jump training (PJT) applied in conjunction with tapering strategies on the jump performance of team-sport athletes. Evidence Acquisition: The meta-analysis included: randomized-controlled studies that incorporated a PJT program; cohorts of team-sport athletes; jump performance assessments; and studies that incorporated a programmed taper. A systematic search was conducted in distinct electronic databases for relevant studies. Aside from jump performance, the extracted data included characteristics of the participants, PJT, and tapering. Means and standard deviations were used to calculate the effect sizes (ES). To assess the effects of moderator variables, subgroup analyses were performed. The statistical significance level was set as p<0.05. Evidence Synthesis: From 7,020 records initially identified, 14 studies were eligible for meta-analysis. Across all included studies, there was a moderate, significant improvement in jump performance (ES=0.73; p<0.001). Additionally, the subgroup analysis demonstrated that the duration and intensity of the taper and the volume of the PJT induced similar improvements in jump performance (p<0.01). Conclusions: In summary, PJT interventions that included a programmed taper induced significant improvements in jump performance in team-sport athletes. These effects were observed after different tapering strategies in terms of volume, taper duration, and the type of PJT prescribed.", "pred_label": "__label__POS", "pred_score_pos": 0.8869295716285706}
{"content": "As we challenge others, we must challenge ourselves 15 June 2020\nOn 2 June GCN expressed our solidarity with the Black Lives Matter movement and with victims of racist police and societal violence everywhere. GCN further denounced the racism and injustice that exist in the UK ‘justice system’ and joined with others doing the same.\nIan Macdonald QC, our founder, stood in solidarity with the black community all his life. He led trials which challenged racist injustices in housing, policing, prosecution and immigration decision making and unfair trial and prosecutorial procedures. As just one example, in the Mangrove Nine trial in 1970, he forced a begrudging judicial acknowledgment of ‘evidence of racial hatred’ in the police. Other members of chambers challenge oppression, discrimination and injustice in their own legal practices.\nChange comes from within\nAs Mira Hammad powerfully explains, it is not enough for a predominantly white (and male) legal profession to hold others to account for racism and discrimination when the profession is guilty of it themselves. GCN is a predominantly white chambers, and has been since it was founded. We know this is one shortfall and that we need to carefully consider and identify others. We do not reflect the diverse backgrounds of our clients. We have not done enough to promote diversity in our own ranks, nor the profession at large. We have not sufficiently challenged our overt and unconscious biases. We have not adequately tackled our part in perpetuating an institutionally racist system.\nWhile silence is not an option, neither is inaction. Now is the moment for GCN to pledge to do better\nand to be accountable through our deeds. These actions cannot be tokenistic.\nAs a chambers we have begun the process of investigating our shortcomings and challenging our assumptions. We are learning how to better make space for black and ethnic minority individuals. We invite all those who support us, instruct us and work with us to assist us in this process and hold us to account along the way.", "pred_label": "__label__POS", "pred_score_pos": 0.5758897066116333}
{"content": "Domain-specific languages are constructed to provide modelling capabilities tailored to a specific domain. Sometimes, languages are developed many times, typically to support application in a new context. In doing so, recurring patterns and commonalities as well as variations across the evolving set of languages can be identified. This paper introduces the concept of a domain-specific metamodelling language, which codifies such commonalities and provides concepts and logic for expressing the variations. The challenges and difficulties of using domain-specific metamodelling languages are identified. We illustrate the concept with examples from different domains.", "pred_label": "__label__POS", "pred_score_pos": 0.998784601688385}
{"content": "Industry OverviewToday, the automotive industry is challenged by the surge in upcoming technology trends – EVs, autonomous driving, shared mobility, and the ever-changing emission norms. Automakers need to adopt strategic initiatives to shape the industry’s evolution while still maintaining profit and channels for expansion. For this, the auto players need to make fundamental changes in their supply chain and procurement networks. They need to search for new avenues of efficiency through cost rationalization in production, vertical integration of vendors and adopt tech-led sourcing and procurement models. The Moglix AdvantageMoglix helps its automotive clients implement world-class digital procurement solutions that provide intuitive catalog exploration, detailed spend analytics, real-time order tracking, and integration with ERP, all of which lead to significant cost savings and an increase in overall efficiency. Moglix insights and strategies to address your most pressing indirect procurement and supply chain challengesLearn more about how we can provide you with tools and support to gain a unique competitive advantage with our unified e-procurement solutions Download E-book Subscribe to our monthly newsletter\nJoin our subscriber’s list to get the latest updates and articles delivered directly to your inbox.", "pred_label": "__label__POS", "pred_score_pos": 0.9561397433280945}
{"content": "Laboratory Studies\nA complete blood count (CBC) may reveal parameters suggestive of infection (eg, leukocytosis), though leukocytosis may be absent in elderly patients. Elevated packed blood cell volume suggests a shift of intravascular fluid. Blood culture for aerobic and anaerobic organisms is indicated. Findings from liver function and renal function tests may be within reference ranges (or nearly so) if no preexisting disorder is present.\nImaging Studies Radiography\nErect radiographs of the chest are recognized as the most appropriate first-line investigation when a perforated peptic ulcer is considered likely.\n[15] However, in approximately 30% of patients, no free gas can be identified. Thus, an erect posteroanterior chest radiograph is not sufficiently sensitive to rule out pneumoperitoneum in patients presenting with upper abdominal pain.\nPlain supine and erect radiographs of the abdomen are the most common first steps in the diagnostic imaging evaluation of patients presenting with medical history and/or clinical signs suggestive of bowel perforation. Findings suggestive of perforation include the following:\nFree air trapped in the subdiaphragmatic locations - If the quantity of free air is great enough, its presence can be visualized on the supine radiograph of the abdomen, allowing clear definition of the inner and outer surface of the wall of the bowel Visible falciform ligament - The ligament may appear as an oblique structure extending from the right upper quadrant toward the umbilicus, particularly when large quantities of gas are present on either side of the ligament Air-fluid level - This is indicated by the presence of hydropneumoperitoneum or pyopneumoperitoneum on erect radiographs of the abdomen\nWater-soluble radiologic contrast media administered orally or through a nasogastric tube can be used as an adjunct diagnostic tool to detect any intraperitoneal leak.\nThe perforation has sealed at presentation in approximately 50% of patients. For those who favor a nonoperative approach, contrast radiology is routine in the management of these patients.\nUltrasonography\nLocalized gas collection related to bowel perforation may be detectable on ultrasonography (US), particularly if it is associated with other visible abnormalities (eg, thickened bowel loop). The site of bowel perforation can be detected by US (eg, gastric vs duodenal perforation, perforated appendicitis vs perforated diverticulitis). Ultrasonograms of the abdomen can also provide rapid evaluation of the liver, spleen, pancreas, kidneys, ovaries, adrenals, and uterus.\nComputed tomography\nComputed tomography (CT) of the abdomen can be a valuable investigative tool, providing differential morphologic information not obtainable with plain radiography or ultrasonography.\nCT scans may provide evidence of localized perforation (eg, perforated duodenal ulcer) with leakage in the area of the gallbladder and right flank with or without free air being apparent. They may show inflammatory changes in the pericolonic soft tissues and focal abscess due to diverticulitis (may mimic perforated colonic carcinoma). CT scans may not provide definitive radiographic evidence of perforated Meckel diverticulitis.\nProcedures\nLaparoscopy may significantly improve surgical decision making in patients with acute abdominal pain, particularly when the need for operation is uncertain.\nPeritoneal diagnostic tap may be useful in determining the presence of intra-abdominal blood, fluid, and pus.\nPeritoneal lavage is more valuable in the presence of a history of blunt abdominal trauma. The presence of blood or purulent material or the detection of bacteria on Gram stain suggests the need for early surgical exploration. Alkaline phosphatase concentration in the peritoneal lavage is a helpful and sensitive test that may be used to detect occult blunt intestinal injuries. A concentration greater than 10 IU/L has been shown to be a sensitive and reliable test in the detection of occult small bowel injuries.\nFine-catheter peritoneal cytology involves the insertion of a venous cannula into the peritoneal cavity, through which a fine umbilical catheter is inserted while the patient is under local anesthesia. Peritoneal fluid is aspirated, placed on a slide, and stained for examination under a light microscope for percentage of polymorphonuclear cells. A value greater than 50% suggests a significant underlying inflammatory process. This test, however, provides no clue as to the exact cause of inflammation.\nTables What would you like to print? Overview Presentation DDx Workup Treatment Questions & Answers", "pred_label": "__label__POS", "pred_score_pos": 0.6751357913017273}
{"content": "We implement Environmental and Social Impact Assessments prior to undertaking greenfield or brownfield expansion projects. These assessments identify potentially affected stakeholders and their representatives, as well as potential impacts from the outset, and provide a framework for developing both stakeholder engagement and mitigation plans. Many of our operations use baseline assessment tools to help identify community needs and provide a baseline against which we can measure our performance over time. Our active mining sites have mine closure plans that specify measures for managing environmental impacts at the end of mine life, while our ongoing community investment programs aim to build community resilience and individual capacity for sustainability post-closure.\nResettlement\nWe are committed to respecting the human rights of community members and, when unavoidable, conducting community resettlement activities in alignment with international best practice. This commitment is reflected in our Community and Human Rights Policies. We did not have any resettlement activities in 2019.\nINDONESIA\nPT-FI completed its Environmental Impact Assessment (AMDAL) in 1997 in compliance with Government of Indonesian regulations and the company’s policies and practices on management of the environmental and social impacts of our operations. The AMDAL, approved by the Government of Indonesia, describes PT-FI’s management plans for environmental and social impacts. PT-FI’s Environmental and Community Affairs departments jointly compile data and program results and submit biannual Environmental Planning and Monitoring Reports to the Government of Indonesia.\nSedimentation Impact Mitigation\nIn 2019, PT-FI continued its collaboration with indigenous Kamoro communities located along the coastal areas of eastern Mimika, in particular Fanamo, Omawita and Otakwa. Some of the traditional waterways used by the Kamoro to access their traditional sources of livelihood have been impacted by the levee extension construction necessary to maintain the safety of our controlled riverine tailings system. PT-FI continued work with these communities on its impact mitigation strategy, which includes regular passenger boats and bus services to improve access between coastal villages and Timika to support the development of economic livelihoods, health and education.\nAcknowledging that sedimentation impact mitigation is a cross-departmental responsibility, PT-FI’s Sedimentation Task Force continues its mitigation measures with key local government, religious institutions and local community stakeholders. This multi-stakeholder approach in mitigating sedimentation impacts resulted in development of both a water transportation program and economic development activities aligned with Kamoro culture and livelihoods. The water transportation program includes an integrated passenger boat and bus service with optimal routes and schedules determined through consultation with local community members and the local Mimika government. During Phase One of the program (2013 – 2018), PT-FI regularly engaged with the affected local communities in planning, implementing, monitoring and evaluating our social mitigation programs addressing the impact of tailings and sedimentation.\nPhase Two of the program began in 2019, with continued enhancements to the local transportation system and an added focus on local economic development – vegetable and coconut farming, and fisheries. Program interventions during 2019 included:\nProviding roundtrip boat service between Pomako and the PT-FI-constructed Omauga dock for the people from Manasari and Otakwa, including 48 return boat trips carrying approximately 750 passengers;\nConstructing a community boat mooring area and bus shelter on the east levee that provides alternative transportation access for communities from the east to Timika;\nProviding transportation for the five directly-impacted Kamoro villages to access their gardens and fishing grounds as well as markets in Timika, including a monthly average of 390 bus trips and 50 truck trips during the year;Securing access to fuel at a competitive price in cooperation with the Catholic Diocese of Timika;\nProviding coconut program assistance covering 200 hectares and 368 farmer groups, including distribution of approximately 26,100 coconut seedlings; and\nOngoing vegetable program assistance including seeds and fertilizer as well as help with marketing, was provided to 177 households, who collectively generated revenue in excess of $178,000\nPT-FI, together with the local government and affected local communities, implements regular monitoring and evaluation to assess the effectiveness of its mitigation programs on impacted communities. Program enhancements resulting from this process have ranged from modifying the type and size of passenger vessels, to improved transportation service routes and schedules with more strategic docking locations.\nIn collaboration with the local government, PT-FI is supporting the establishment of an economic and transportation hub in Otakwa village located to the east of Timika. The hub will support the establishment of an Integrated Center for Marine and Fishery Activities as well as an increase in coastal transportation access for Kamoro communities located east of the current network. This hub also will facilitate access of these coastal communities to the east to economic and social infrastructure.\nPlease refer to the Community Engagement and Social Investments sections for additional information on Community and Economic Development programs in Indonesia.\nCommunity Grievance Mechanisms\nTo support constructive engagement and resolution of issues that may arise, we maintain site-level grievance mechanisms where community members can share their questions, concerns and/or complaints, outside of any other engagement forum. The community grievance mechanisms are part of our commitment to provide access to remedy. They also serve as an early warning system and help to manage and reduce potential risks by identifying and addressing problems before potential escalation into larger conflicts.\nOur community grievance mechanisms are available in local languages, tailored to local cultures and allow us to document issues and concerns raised by local community members and responding a timely manner. Grievances are typically received by community engagement team members in the field, through engagement at established company/community forums, in writing via physical drop boxes or via local telephone hotlines. Regardless of how they are received, they are reported to the site Community Grievance Officer, who relays the grievance to the relevant department for evaluation. Community engagement team members help investigate grievances and work with community members to acknowledge the grievance, address concerns, solve problems and mitigate or remedy impacts, For grievances with potentially high community impacts, senior management and applicable government authorities are engaged, as appropriate.\nDuring 2019, our global operations recorded 170 community grievances in our web based management system predominantly regarding community benefits, environmental concerns, health and safety and land rights. This system allows us to track grievances, identify thematic trends, report resolutions and measure our performance.\nThe ICMM’s update good practice guidance on Handling and Resolving Local-level Concerns and Grievances, together with input from community members and their representatives, are informing updates to our community mechanisms anticipated for rollout in 2021. This guidance strengthens the effectiveness criteria outlined in the UNGPs.\nAMERICAS\nSierrita\nSierrita successfully resolved 725 grievances received in late 2018 and early 2019 associated with the six-hour, 500-year storm event that damaged the Sierrita Tailings Impoundment (STI) surface crust layer in late 2018. High winds during subsequent storms blew dust towards the adjacent Green Valley and Sahuarita communities resulting in dust-related impacts. Remedies were agreed with residents based on household-specific impacts and included organizing or reimbursing professional cleaning services for homes, cars and HVAC systems, as well as providing a Human Health Impact Assessment report on the non-toxic nature of the tailings material to circumvent misperceptions or concerns. To mitigate the risk of recurring impacts, Sierrita conducted a benchmark evaluation to inform updates to its Tailings Management and Stewardship Program (TMSP), including how to better anticipate and prepare for storm events to reduce dust emissions. Sierrita continues its engagement with neighboring communities, providing through regular communications, hosting and attending community meetings, conducting site tours, and having frequent discussions with government and regulatory stakeholders regarding the TMSP. Grievance resolution was ongoing for two cases as of the end of 2019.\nMorenci\nThe Coronado Trail Scenic Byway (Highway 191) winds through Morenci in Greenlee County, Arizona, drawing tourists and providing critical access for ranchers in remote Upper Eagle Creek. On February 28, 2019, the Arizona Department of Transportation (ADOT) closed the Coronado Bridge located between Morenci to Alpine on Highway 191 without advance notice due to unexpected deterioration to the abutment. Vehicles were redirected through New Mexico – a 100 mile re-route. This impacted both tourism and ranchers’ ability to secure supplies for their animals and fuel for the generators used to heat their homes. When ranchers raised concerns regarding the timeline for the bridge repairs, Freeport-McMoRan and Greenlee County enacted their Emergency Management Mutual Aid Agreement plan to open a transportation route through Morenci’s operational areas for critical supplies and emergencies during the bridge closure. Morenci also provided hay to Greenlee County, which was delivered to the ranchers along with fuel, mail, prescriptions, and other critical supplies for Upper Eagle Creek residents. At the same time, Morenci collaborated with ADOT to expedite repair works by reassigning mining equipment to shore up the bridges’ existing abutment. These reinforcements allowed the bridge to be re-opened while ADOT completed additional repairs. Adjustments to mining operations enabled ranchers to transport their livestock to market on time, tourists to visit Greenlee County, and minimized quality of life impacts for residents of Upper Eagle Creek. The Coronado Bridge reopened on March 25, 38 days ahead of schedule.\nEl Abra\nA major flood event that struck El Abra operations in early 2019 caused extensive damage throughout the Alto El Loa region of the Atacama Desert, including the Indigenous community of Conchi Viejo. Already vulnerable, indigenous communities were particularly impacted as the heavy rainfall washed out local roads and destroyed homes and infrastructure. Working with the affected communities, an emergency response plan was quickly developed, supporting immediate actions to address basic needs including transport, shelter and access to food and water. While restoring its operational infrastructure, El Abra prioritized community support by assisting with clearing and repairing roads, as well as providing construction materials for damaged homes. After the immediate response to the flood event, El Abra developed a reconstruction plan – a formal commitment supporting tasks that included removing flood debris, filling sinkholes, repairing homes, rehabilitating irrigation channels, and enhancing drinking water systems. The Conchi Viejo community celebrated the first phase of the town's reconstruction in October 2019 with remaining phases scheduled to be completed in 2020.\nINDONESIA\nPT-FI received and responded to two grievances from Kamoro community members regarding the impact of sedimentation on local transportation routes and certain economic activities in 2019. Acknowledging that sedimentation impact mitigation is a cross-departmental responsibility, PTFI’s sedimentation task force continues its mitigation measures through strengthening existing partnerships with key local government, religious institution and local community stakeholders on establishing an economic and transportation hub in Otakwa village to the east of Timika. The hub will support establishing an Integrated Center for Marine and Fishery Activities and an increase in coastal transportation access for Kamoro communities located east of the current network. This hub, when fully operational, will also facilitate access of these coastal communities to the east to economic and social infrastructure.\nIn 2019, PT-FI also recorded 15 formal land rights grievances from members of the indigenous Papuan communities, including claims over land use and compensation requested for past land use agreements. PT-FI received and processed these community grievances through its community grievance mechanism. This included working with local authorities to investigate the claims or grievances with the goal to reach a mutually acceptable agreement within existing legal frameworks of the host government. A 2014 land rights mapping study conducted by Cenderawasih University continues to assist the Amungme traditional council (Lemasa) and PT-FI in mediating conflicts over land rights claims in highland areas. Please refer to Land Use & Customary Rights section for more information.\nBACK TO COMMUNITIES > Community Investment & Social Investments | ASSESSING & MANAGING IMPACTS | Public Health | Artisanal Mining | Freeport in My Community", "pred_label": "__label__POS", "pred_score_pos": 0.6027365326881409}
{"content": "The stock market is a great place to invest in the long-term. However, if you don’t want to invest directly in stocks, a good alternative is to invest in equity funds. Equity funds are pooled funds that invest primarily in the stock market. They can either be a Unit Investment Trust Fund (UITF), a mutual […]", "pred_label": "__label__POS", "pred_score_pos": 0.8481889963150024}
{"content": "Abstract\nConsolidation radiotherapy (cRT) in patients with stage I/II diffuse large B-cell lymphoma of the Waldeyer's ring (WR-DLBCL) in complete remission (CR) after induction chemotherapy (CHT) is often associated with relevant acute and chronic toxicity, and its impact on survival remains to be defined. A total of 184 patients in CR after anthracycline-based chemotherapy were retrospectively analyzed: 62 underwent CHT alone (CHT group), while 122 (66%) patients were referred to cRT (CHT + RT group). After a median follow-up of 54 months, 36 patients (20%) experienced relapse: 19% in the CHT group and 20% in the CHT + RT group. At the time of analysis 47 (76%) CHT patients and 97 (80%) CHT + RT patients were alive. Five-year overall survival (OS), disease-free survival (DFS) and lymphoma-specific survival (LSS) were 80%, 74% and 86%, respectively. Five-year OS was significantly prolonged in the CHT + RT group, while DFS and LSS were similar between groups. This discrepancy was attributed to a high percentage of deaths due to unrelated causes in CHT patients. cRT does not prolong LSS in patients with early-stage WR-DLBCL in CR after anthracycline-containing chemotherapy. An international confirmatory trial is warranted.\nKeywords Chemotherapy DLBCL Lymphoma Radiotherapy Waldeyer ASJC Scopus subject areas Hematology Oncology Cancer Research", "pred_label": "__label__POS", "pred_score_pos": 0.8392045497894287}
{"content": "Abstract\nThe structure of any religion is based on signs and meanings, i.e. intentions and recognitions, as well the production/consumption of messages showing collective identity and memory. Through the semiosis process, space is perceived as a representation or a manifestation of something else (like the spatial recognition of a hierophany). Believers perceive the heterogeneity and the sacralization of space, distinguishing it from the “profane”. This distinction produces meanings and transforms space into a spiritual and cultural heritage. This article argues the sacralization of space and its physical (geographical) and psychological (“mythopoietic”) factors. Following a theoretical perspective, the aims are a) to address the influence of geography over the sacred; b) to reveal the role of the resemantization and sacralization for the spatial organization of places; and c) to emphasize the genesis and dynamics of sacred space and its recreation in a collective psychology.\nOriginal language English Pages (from-to) 343-360 Journal Versus – Quaderni di Studi Semiotici Issue number 125 Publication status Published - 2017", "pred_label": "__label__POS", "pred_score_pos": 0.753714919090271}
{"content": "Sara Boyd grew up in Sedro-Woolley, Washington, in low socioeconomic conditions. Because of this, she knew that her potential for going to college was limited or nonexistent, and decided on enlisting in the Military to both serve the country as well as to earn the opportunity to attend college.\nAs per standard military procedure, without informed consent or the right to refuse without the threat of dishonorable discharge, she was injected with various vaccines, all undocumented, including a vaccination for Anthrax that triggered a negative reaction.\nThis negative reaction played out as decreasing health over the span of her ten year military career. This decreasing health was marked with constant illness, chronic fatigue, pain, limb swelling, and a decline in cognition. Ultimately, she would learn that the vaccine poisoned her.\nWhen she brought her condition to the attention of the Military and Veterans Affairs, they coldly rejected her claim that the vaccine (or vaccines) had caused her debilitating symptoms.\nThe Military has used soldiers as animal experiments for decades, injecting them with multiple vaccines, watching the poisoned soldiers decline and becoming permanently disabled, and denying that their coerced vaccinations and threat of dishonorable discharge had anything to do with their slide from highly fit and healthy to permanently debilitated.\nSara became a Staff Sargent and stationed in South Korea for Intelligence gathering, but had declined in physical and cognitive functioning that her decline forced her into early retirement.\nSara’s plight mirrors millions of vaccine poisoned soldiers struggling mightily for a return to the high level of fitness, physically and mentally, as they were before the forced chemical cocktail vaccinations.\nShe has created the nonprofit, GWI Operation Truth, which is trying to ensure that future soldiers have the right to refuse vaccinations, and making all vaccine injured soldiers eligible for VA health assistance.\nCurrently over a million soldiers are debilitated and disabled by the forced vaccinations without informed consent, and VA refusing to treat them for the intentional poisoning.\nStaff Sargent Sara Boyd is dedicating her life to gaining justice for herself and for her soldier brethren who had their human rights violated when they were forced to get injected without their informed consent and were subsequently injured by the toxic vaccines.", "pred_label": "__label__POS", "pred_score_pos": 0.8541033864021301}
{"content": "In Indonesia, around 140,000 – 187,000 hectares of agriculture areas have been lost due to residential or industrial purposes every year, especially on Java Island. This research attempted to explore the viable method of rice farming in peatland which has the potential to be cultivated as arable land. Download our slides used during the International Conference on Sustainable Agriculture (ICOSA) 2020 on this page. The video of the presentation is available on our Youtube’s page.\nBagikan Topik Tahun Publikasi Ukuran File\n5.53 MB", "pred_label": "__label__POS", "pred_score_pos": 0.8550822734832764}
{"content": "Abstract\nWe evaluated genetic variations in the non-structural carbohydrate (NSC) and the cell-wall components of stem in rice, sorghum, and sugar cane to assess the potential suitability of these gramineous crops for bioethanol production. For NSC, the maximum soluble sugar concentration was highest in sugar cane, followed by sorghum with sucrose. The major NSC in rice was starch, but there were wide variations in the starch to soluble sugar ratios among the cultivars. The total concentration of cell-wall components was negatively correlated with the NSC concentration, indicating competition for carbon sources. Among the cell-wall components, lignin was relatively stable within each group. The major sugar species composing hemicellulose was xylose in all crop groups, but there were differences in composition, with a higher fraction of arabinose and glucose in rice as compared to the other crops. In rice, there was less lignin than in sorghum or sugar cane; this might be advantageous for the efficient saccharification of cellulose.\nKeywords Cell-wall carbohydrate components Nonstructural carbohydrate Rice Sorghum Sugar cane ASJC Scopus subject areas Biotechnology Analytical Chemistry Biochemistry Applied Microbiology and Biotechnology Molecular Biology Organic Chemistry", "pred_label": "__label__POS", "pred_score_pos": 0.6254235506057739}
{"content": "How much Vitamin C is in one capsule?\nActive Iron contains a small quantity (about 18mg) of vitamin C which acts as a preservative within the formulation.\nVitamin C, if taken in large doses (250-500 mg) can improve the absorption of iron. However, the quantity of vitamin C in Active Iron is not enough to enhance absorption.\nActive Iron has been clinically proven to ensure better absorption of iron. There is no need to use an ‘enhancer’ like Vitamin C to boost absorption further. However, there is no issue you wish to take Active Iron with a vitamin C supplement or a glass of orange juice.", "pred_label": "__label__POS", "pred_score_pos": 0.8409796953201294}
{"content": "This guide provides a brief overview of the issues law enforcement should consider when working with immigrant communities, and in particular immigrant victims of crime by: exploring various immigration laws and terms that officers need to know; examining the challenges immigrant crime victims face navigating the justice system; identifying how officers can protect and assist immigrant crime victims while managing their enforcement role.\nSearch for similar resources", "pred_label": "__label__POS", "pred_score_pos": 0.9993380904197693}
{"content": "Abstract\nHydrogen peroxide (H\n2O 2) is a kind of ideal green propellant. It is crucial to study the wear behavior and failure modes of the metal materials under the strong oxidizing environment of H 2O 2. This study aims to investigate the wear of rubbing pairs of 2Cr13 stainless steel against 1045 metal in H 2O 2 solutions, which has a great effect on wear, the decomposition and damage mechanism of materials. The comparison analysis of the friction coefficients, wear mass loss, worn surface topographies and current densities was conducted under different concentrations of H 2O 2 solutions. There were significant differences in the tribological and electrochemistry properties of the rubbing pairs in different H 2O 2 solutions.", "pred_label": "__label__POS", "pred_score_pos": 0.7217473983764648}
{"content": "Verges What is a verge?\nThe verge is the part of the street between the carriageway (kerb line and road) and the property boundary of the land which abuts the street, but does not include any footpath.\nThe verge can often be referred to as the nature strip.\nThe verge is crown land that is under the care, control and management of the City. Underground services such as power, water, gas and telecommunications as well as drainage infrastructure have standard alignments within this space. As these services are located within the verge, they may need to be accessed by the service provider or the City and therefore the verge may be dug up. You will always be advised before this occurs, unless it is an emergency situation.\nThe City acknowledges the care residents take in maintaining verges, improving the overall appearance of the street and their properties.\nApproval is not required when permissible verge treatments are installed. If you wish to do anything outside this list, you must submit a request in writing outlining your proposal to the City for consideration.\nWhen doing building or demolition works on a property a verge permit is compulsory for:\ntemporarily parking vehicles\nstoring materials\nplacing a bulk bin or\naccessing the property across the verge\nStreet trees are usually provided for each property. Residents and ratepayers are prohibited from removing, pruning or tampering in any way with street trees. Please refer to the street tree management document for further information.", "pred_label": "__label__POS", "pred_score_pos": 0.8357965350151062}
{"content": "Exports of electronic products from Singapore grew by 0.7 per cent on a year-on-year basis in November in contrast to the 3.2 per cent decrease in the previous month. The growth was largely due to telecommunications equipment (41.4 per cent), other computer peripherals (80 per cent), and diodes and transistors (6.5 per cent), it was reported by the trade agency.\nNon-electronic exports declined by 5.1 per cent, compared with the 1.4 per cent rise in the previous month. This decline was led by pharmaceuticals (-12.5 per cent), structural parts (-91.3 per cent) and food preparations (-24.6 per cent).\nExports to all of the top 10 markets – except the US, Japan, Thailand and South Korea – fell last month. The main contributors to the decline were China, Malaysia and the European Union, according to IE Singapore, which drives Singapore’s external trade.", "pred_label": "__label__POS", "pred_score_pos": 0.597929835319519}
{"content": "What you’ll learn: Contributions to a noisy environment The challenges and risks that security teams face amid too much noise Key tactics to help cut through the noise and improve your security efficiency\nSecurity teams today are tasked with managing an overwhelming number of incoming alerts. A noisy environment can increase the risk of missing a real threat or potential breach incident.\nCutting through the noise requires an evaluation of your security strategy to ensure you’re enabling your team to focus on the right alerts without letting any threats slip by.", "pred_label": "__label__POS", "pred_score_pos": 0.5703731179237366}
{"content": "If your doctor has recommended radiation therapy as part of your cancer treatment, you may have many questions.\nWhat is radiation therapy?\nWill it hurt?\nWill I have bad side effects?\nHow is radiation given?\nWill it cure my cancer?\nThe video below will walk you through the basics of radiation therapy. I hope you find it helpful.", "pred_label": "__label__POS", "pred_score_pos": 0.8975967764854431}
{"content": "ScienceDaily (Aug. 31, 2010) — A study carried out by cardiologists from the Medical University of Innsbruck has investigated the risk of myocardial infarction (heart attack) amongst winter sports tourists to the Tyrolean Alps. The research, presented at the European Society of Cardiology's Congress 2010 in Stockholm, shows that inadequate preparation for the intense physical exertion required, combined with the effects of altitude and low temperature, leads to an increase in heart attack incidents, particularly during the first two days of vacation.\nhttp://www.sciencedaily.com/releases/2010/08/100831104645.htm", "pred_label": "__label__POS", "pred_score_pos": 0.5438507199287415}
{"content": "This 3D illustration of the limbic system places the focus on the amygdalae, two small pea-shaped structures on either side of the limbic system that play a crucial role in the processing of emotional memory and experiences, including fear and anxiety. Over-activated amygdalae are central to the inappropriate reactions experienced by people who suffer from chronic phobias, obsessions and generalized anxiety.\nKeywords:\n© Audra Geras", "pred_label": "__label__POS", "pred_score_pos": 0.9848496913909912}
{"content": "Design for reliability is becoming an important step in the design cycle with CMOS technology scaling, demanding need for efficient and accurate reliability simulation methods in the design stage. Traditional aging analysis does not differentiate NBTI induced delay shift in rising and falling edges, thereby assuming averaging effect due to recovery. It is essential to identify the critical operation conditions that are more susceptible to timing violations under aging. In this paper, by identifying the critical moments in circuit operation and considering the asymmetric aging effects, timing violations under NBTI effect are correctly predicted. The unique features of this work include: (1) delay modeling of a digital gate due to threshold voltage (V\nth) shift using delay dependence on supply voltage from cell library; (2) asymmetric aging analysis is conducted by recognizing the critical points in circuit operation; and (3) setup and hold timing violations due to NBTI induced path delay shift in logic and clock buffer are investigated. This failure assessment method is further demonstrated in ISCAS89 benchmark circuits using 45nm Nangate standard cell library to extract aging information in critical paths. The proposed failure diagnosis enables resilient design techniques to mitigate circuit aging under NBTI.", "pred_label": "__label__POS", "pred_score_pos": 0.9969802498817444}
{"content": "Abstract\nHistorically, patients with peritoneal carcinomatosis secondary to colorectal cancer have a poor overall prognosis. Recent data support the use of cytoreductive surgery and heated intraperitoneal chemotherapy (CRS + HIPEC) to specifically address the peritoneal disease. Retrospective studies on CRS + HIPEC have been promising, showing significant improvements in OS compared with systemic chemotherapy alone. However, CRS + HIPEC carries morbidity similar to other advance oncology procedures such as liver resection and pancreatoduonectomy. It is hoped that ongoing clinical trials will clarify its role in the treatment of patients with peritoneal metastatic colorectal cancer.\nKeywords CC score Cytoreductive surgery (CRS) Hyperthermic intraperitoneal chemotherapy (HIPEC) Intraperitoneal chemotherapy (IP) Peritoneal carcinoma index (PCI) Peritoneal metastasis (PM) R score ASJC Scopus subject areas Surgery", "pred_label": "__label__POS", "pred_score_pos": 0.7880827188491821}
{"content": "Can Webcams Take Pictures of You Without You Knowing?\nBy Todd Bowerman\nA webcam on your laptop or desktop computer allows you to record video content and chat with people across the globe, but also opens a small window into your home. Keeping the webcam safe from hackers and other trespassers is critical if you want to protect your privacy. Unprotected webcams are easily accessible to malicious Web users.\nSite Vulnerabilities\nEvery website you visit is a potential security risk, even for your webcam. While the majority of spyware and virus programs are designed to steal information, an application that delivers remote access to your webcam can also be injected via worm or Trojan. If a hacker has access to your system due to some malicious code somewhere on your hard drive, that hacker can theoretically enable and control any connected peripherals at will.\nSecure Networks\nEverything you do on your wireless network is easily accessible to anyone with access. If your network is not secured with a strong password, a hacker can enter the network and gain access to any device connected to it. This includes webcams. The hacker would have to be within range of the network for this method to work, but it's still important to lock down your wireless network just to be sure.\nIdle Computers\nIf you leave your computer on and active when you're not using it, you're giving hackers and thieves the perfect opportunity to access your devices and content without your being aware. In fact, it doesn't take a hacker's mind to access an idle, unprotected camera – sites exist that allow even regular computer users to browse hundreds of cameras connected to the Web but not secured. Shutting down your computer when not in use, or closing the laptop lid, helps keep it and you safe.\nPrevention\nWhile it's true that hackers and other individuals can access webcams without your permission, there are a few things you can do to keep yourself safe. Lock your network with a password, install a robust suite of anti-virus and anti-spyware software, keep your firewall active and remind everyone in your home to follow safe browsing practices. Covering the webcam with tape or disconnecting it between uses will ensure no one sees anything you don't want them to see.", "pred_label": "__label__POS", "pred_score_pos": 0.875687837600708}
{"content": "Abstract\nPURPOSE: To investigate agreement between the predicted ablation depth calculated by the EX500 excimer laser (Wavelight Laser Technologie AG, Erlangen, Germany) and the measured ablation depth in eyes that have undergone femtosecond laser-assisted LASIK (FSLASIK) for myopia. METHODS: Corneal thickness was measured with a rotating Scheimpflug camera preoperatively and 3 months postoperatively and the difference between these values was defined as the measured ablation depth. The difference between the predicted and the measured ablation depth was defined as the difference in ablation depth (ΔAD). RESULTS: In 85 eyes of 85 patients, no statistically significant difference was detected between the mean predicted ablation depth (66.33 ± 24.15 μm) and the measured ablation depth at the thinnest corneal location (67.04 ± 30.94 μm), the corneal apex (67.52 ± 31.22 μm), or the pupil center (67.73 ± 31.48 μm). Bland-Altman plots revealed moderate agreement for measurements at the thinnest point (95% limits of agreement [LoA]: -25.13 to 23.70 μm), corneal apex (95% LoA: -24.70 to 22.33 μm), and pupil center (95% LoA: -25.30 to 22.51 μm), with a proportional bias between the average ablation depth and DAD. The predicted ablation depth was overestimated in eyes with lower correction and underestimated in eyes with higher correction.\nASJC Scopus subject areas Ophthalmology Surgery", "pred_label": "__label__POS", "pred_score_pos": 0.720323920249939}
{"content": "Abstract\nEndothelial cells (EC) are the main target for Orientia tsutsugamushi infection and EC dysfunction is a hallmark of severe scrub typhus in patients. However, the molecular basis of EC dysfunction and its impact on infection outcome are poorly understood. We found that C57BL/6 mice that received a lethal dose of O. tsutsugamushi Karp strain had a significant increase in the expression of IL-33 and its receptor ST2L in the kidneys and liver, but a rapid reduction of IL-33 in the lungs. We also found exacerbated EC stress and activation in the kidneys of infected mice, as evidenced by elevated angiopoietin (Ang) 2/Ang1 ratio, increased endothelin 1 (ET-1) and endothelial nitric oxide synthase (eNOS) expression. Such responses were significantly attenuated in the IL-33\n-/- mice. Importantly, IL-33 -/- mice also had markedly attenuated disease due to reduced EC stress and cellular apoptosis. To confirm the biological role of IL-33, we challenged wild-type (WT) mice with a sub-lethal dose of O. tsutsugamushi and gave mice recombinant IL-33 (rIL-33) every 2 days for 10 days. Exogenous IL-33 significantly increased disease severity and lethality, which correlated with increased EC stress and activation, increased CXCL1 and CXCL2 chemokines, but decreased anti-apoptotic gene BCL-2 in the kidneys. To further examine the role of EC stress, we infected human umbilical vein endothelial cells (HUVEC) in vitro. We found an infection dose-dependent increase in the expression of IL-33, ST2L soluble ST2 (sST2), and the Ang2/Ang1 ratio at 24 and 48 hours post-infection. This study indicates a pathogenic role of alarmin IL-33 in a murine model of scrub typhus and highlights infection-triggered EC damage and IL-33-mediated pathological changes during the course of Orientia infection. ASJC Scopus subject areas Public Health, Environmental and Occupational Health Infectious Diseases", "pred_label": "__label__POS", "pred_score_pos": 0.7643579244613647}
{"content": "By Amarica Rafanelli 10/22/20, for The Fix.com\nNew and expectant mothers face unique challenges when seeking treatment for an opioid use disorder. On top of preparing for motherhood, expectant mothers often face barriers to accessing treatment, which typically involves taking safer opioids to reduce dependency over time. The approach is called medication assisted therapy, or MAT, and is a key component in most opioid treatment programs.\nBut with pregnant women, providers can be hesitant to administer opiate-based drugs.", "pred_label": "__label__POS", "pred_score_pos": 0.9999641180038452}
{"content": "According to a new study, a detailed analysis of antibody responses in patients affected by coronavirus disease 2019 (COVID-19) could help develop an effective vaccine.\nImage Credit: National Institute of Allergy and Infectious Diseases, 2020.\nThe study was published in\nPLOS Pathogens—an open-access journal—on September 10 th, 2020, by Chao Wu and Rui Huang from Nanjing University Medical School and collaborators.\nThe latest outcomes prove that the neutralizing activity of antibodies from patients who recovered from COVID-19 is generally not powerful and decreases sharply within a month of hospital discharge.\nThe entire world is facing an unparalleled challenge with economies and communities affected by the rising COVID-19 pandemic. At present, no effective drugs or vaccine have been approved to prevent or treat the disease.\nA better interpretation of antibody responses against the SARS-CoV-2 virus, which is responsible for causing the COVID-19 infection, will offer underlying information for designing effective therapies and a preventive vaccine.\nIn the new research work, scientists constantly tracked SARS-CoV-2-specific antibody reactions in 7 severe COVID-19 and 19 non-severe patients for a period of seven weeks from the onset of disease.\nA majority of the patients produced antibody responses against the SARS-CoV-2 virus, such as the viral nucleoprotein and three portions of the spike protein—the ectodomain, S1 protein, and receptor-binding domain.\nWhile 80.7% of recovered COVID-19 patients had different levels of antibody neutralization activity against the SARS-CoV-2 virus, only a small number of patients elicited a strong level of neutralization activity.\nThis finding emphasizes the significance of meticulously choosing blood samples from the recovered COVID-19 patients using antibody neutralization assays before administrating them into other COVID-19 patients.\nThree to four weeks following hospital discharge, the neutralizing activity of antibodies from the recovered patients decreased considerably, implying that the recovered COVID-19 patients could be probably re-infected with the SARS-CoV-2 virus.\nAdditionally, patients with severe COVID-19 exhibited a huge amount of non-neutralizing antibodies, which may contribute to the antibody-dependent improvement of infection. According to the study’s authors, the new study offers significant insights for antibody-based intervention, vaccine design, and serological testing.\nSource:\nJournal reference:\nChen, Y.,\net al. (2020) A comprehensive, longitudinal analysis of humoral responses specific to four recombinant antigens of SARS-CoV-2 in severe and non-severe COVID-19 patients. PLOS Pathogens. doi.org/10.1371/journal.ppat.", "pred_label": "__label__POS", "pred_score_pos": 0.9472358822822571}
{"content": "If the financial industry still held any objections to the case for providing firmwide communications flexibility and remote working capabilities, March 2020 saw the argument’s proverbial microphone drop.\nIn addition to the functional challenges of navigating market swings and record highs in volumes and volatility,¹ pandemic conditions compelled most global market participants to quickly transfer almost all personnel to home working environments.\nWhile operational disruption affected nearly every institution in the financial industry, Greenwich Associates estimates that over two-thirds of firms experienced varying degrees of avoidable challenges² on top of the unavoidable ones.Methodology\nIn the second quarter of 2020, Greenwich Associates conducted over 30 interviews with U.S.-based representatives from banks, broker-dealers, buy-side firms, exchanges, regulators, and financial technology providers. Information gathered from these interviews, which focused on the operational and functional challenges experienced by compliance teams during the unfolding events of the COVID-19 crisis, informed the qualitative analysis expressed in this report, along with other proprietary Greenwich Associates market research. Additionally, where indicated, select data was provided by and used with the express permission of Bloomberg LP.", "pred_label": "__label__POS", "pred_score_pos": 0.9926276803016663}
{"content": "Isotropic superfinishing is an ideal method of removing the problematic white layer created during the nitriding process.\nBy: Nathan Michaud Developed in the early 20th century, nitriding has evolved into a standard process across many industrial applications. Often considered the simplest technique for case hardening, the process is commonplace in aircraft manufacturing, bearings, automotive components, turbine generation systems, and various industrial machineries [1]. Modern practitioners have perfected nitriding into…", "pred_label": "__label__POS", "pred_score_pos": 0.9677556753158569}
{"content": "Enabling High Purity in Critical Applications\nFluoropolymers play an essential role in chip manufacturing. Even the smallest trace impurities or certain elemental materials can create significant impact to device yields. Chemours manufactures its resins to maintain the highest levels of purity.\nChemours regularly analyzes products to verify their compliance with both internal and industry inspections, including ASTM and SEMI. This analysis helps to achieve and maintain the lowest levels of surface extractable ionic, metal, and total organic carbon content. Properly processed components produced with Teflon™ fluoropolymer resins are used successfully in applications requiring SEMI F57¹ and SEMI C90² compliance.\n¹SEMI F57: Specification for Polymer Materials and Components Used in Ultrapure Water and Liquid Chemical Distribution Systems\n²SEMI C90: Test Method and Specification for Testing Perfluoroalkoxy (PFA) Materials Used in Liquid Chemical Distribution Systems", "pred_label": "__label__POS", "pred_score_pos": 0.7592017650604248}
{"content": "A NEW series of pH and reference electrodes from Sensorex promise the performance of mercury chloride (calomel) electrodes but without the mercury and its associated hazards.\nThe new ‘calomel-free’ electrodes are available in a glass or thermoplastic body, and feature a silver/silver chloride (Ag/AgCl)-based double junction reference. They incorporate a silver ion trap to prevent contamination with silver-sensitive samples. The reference output is adjusted to deliver the same output as calomel electrodes using a silver chloride reference.\nElectrodes are available in a combination model featuring a pH cell and a reference cell in a single body, with separate reference half-cells also available, and in both sealed and refillable reference styles. Gel-filled sealed references are maintenance-free, while refillable designs offer extended electrode life.\nMeasurement range of is a full 0-14pH (0-12.3pH without Na+ error) with a response speed of >95% in one second. They feature an isopotential point of pH 7.00 (0mV), an offset of +/-0.20pH and a span of 97% or higher. The electrodes operate up to 60C.\nCalomel Free Electrodes are also available in several different length and diameter requirements, including the popular 12x150mm Epoxy Body Combination pH Sealed Reference. All Sensorex electrodes are supplied with a 76cm cable, soaker storage bottle or soaker cap, and BNC connector, and are suitable for virtually every meter on the market today.", "pred_label": "__label__POS", "pred_score_pos": 0.9169979691505432}
{"content": "This week, the Postsecondary Data Collaborative (PostsecData) submitted a\nletter to President-elect Donald J. Trump's transition team, offering an agenda to guide the incoming administration's efforts to support student success through improved postsecondary data. PostsecData, a coalition of thirty-six organizations led by the Institute for Higher Education Policy, is committed to the use of high-quality postsecondary data to improve student outcomes, particularly for low-income students and students of color.\nIn this letter, the signers offer a series of administrative actions for President-elect Trump's first 100 days in office, as well as strategies for the longer term. These recommendations focus on improving data quality, consistency, stewardship, and use, while leveraging existing data systems and ultimately reducing burden on institutions.\nThis letter's signatories, listed below, appreciate the opportunity to work with the incoming Trump administration to pursue data-driven policies that will help inform decision-making, institutional practice, and ultimately, student success.\nSignatories to Postsecondary Data Collaborative letter to President-elect Trump's transition team:\nAdvance CTE\nAchieving the Dream\nAssociation for Career and Technical Education\nCenter for Law and Social Policy\nThe Education Trust\nGeorge Washington Institute of Public Policy\nGeorgetown University Center on Education and the Workforce\nInstitute for Higher Education Policy\nNew America\nThe Institute for College Access & Success\nuAspire\nWorkforce Data Quality Campaign\nYoung Invincibles", "pred_label": "__label__POS", "pred_score_pos": 0.8799294233322144}
{"content": "Discrimination Issues Psychological Assessment - Discrimination Issues Discrimination, whether it is based on race, sexual preference, gender, religion, ethnic background, age, disability, national origin, or another factor, can have a profound and damaging psychological impact on a person. Psychologists can evaluate that emotional impact. Psychological evaluations to assess the effects of discrimination must consider many of the same issues addressed in evaluating sexual harassment. After all, sexual harassment is a specific form of discrimination, only it can also include additional behavioral trauma, as well as the emotional damage. There needs to be a distinction made between perception of discrimination and the legal definition of discrimination, which is a legal issue, not a psychological one. However, beyond that issue, psychologists can assess whether an individual presents with psychological distress or a disorder, and whether this condition appears to be preexisting the alleged discrimination, or as a result of the incident. Psychologists can also identify the functional emotional impairments that have resulted from the discrimination, including any disability, if evident. When discrimination occurs within the workplace, it can create a hostile work environment that not only results in distress, but can limit a person's capacity to care for themselves and their family, because it affects their capacity to earn a living. Psychologists can offer an opinion regarding whether a person's expectations about how s/he was treated were reasonable, based on the circumstances of the incidents. The ultimate determination, regarding whether discrimination took place or not, is made by the court, but a psychological assessment can describe the extent of emotional harm and the potential for recovery, if discrimination is established. Dr. Franklin provides psychological evaluiations to assess the emotional impact of discrimination. For more information, call (908) 526-8111.", "pred_label": "__label__POS", "pred_score_pos": 0.934844434261322}
{"content": "Many global automotive companies have been putting efforts to reduce traffic accidents by developing advanced driver assistance system (ADAS) as well as autonomous vehicles. Lane detection is essential for both autonomous driving and ADAS because the vehicle must follow the lane. However, existing lane detection algorithms have been struggling in achieving robust performance under real-world road conditions where poor road markings, surrounding obstacles, and guardrails are present. Therefore, in this paper, we propose a multi-lane detection algorithm that is robust to the challenging road conditions. To solve the above problems, we introduce three key technologies. First, an adaptive threshold is applied to extract strong lane features from images with obstacles and barely visible lanes. Next, since erroneous lane features can be extracted, an improved RANdom SAmple Consensus algorithm is introduced by using the feedback from lane edge angles and the curvature of lane history to prevent false lane detection. Finally, the lane detection performance is greatly improved by selecting only the lanes that are verified through the lane classification algorithm. The proposed algorithm is evaluated on our dataset that captures challenging road conditions. The proposed method performs better than the state-of-the-art method, showing 3% higher True Positive Rate and 2% lower False Positive Rate performance.", "pred_label": "__label__POS", "pred_score_pos": 0.9939098954200745}
{"content": "A recent survey found that, regardless of age, nearly three quarters of adults said they enjoy magazines, even when they can have access to the same content online. Another interesting finding – respondents overall were more receptive to print advertising than to internet ads. This suggests that targeting your audience through carefully chosen print media remains an effective marketing strategy – provided you have something compelling to say in an engaging and memorable way.", "pred_label": "__label__POS", "pred_score_pos": 0.9999164938926697}
{"content": "Geophysical fluid flows are predominantly turbulent and often strongly affected by the Earth's rotation, as well as by stable density stratification. Using direct numerical simulations of forced Boussinesq equations, we study the influence of these effects on the motion of fluid particles. We perform a detailed study of Lagrangian statistics of acceleration, velocity, and related quantities, focusing on cases where the frequencies associated with rotation and stratification (RaS), f and N, respectively, are held at a fixed ratio N/f = 5. The simulations are performed in a periodic domain, at Reynolds number Re approximate to 4000, and Froude number Fr in the range 0.03 less than or similar to Fr less than or similar to 0.2 (with Rossby number Ro = 5Fr). As the intensity of RaS increases, a sharp transition is observed between a regime dominated by eddies to a regime dominated by waves, which corresponds to Fr less than or similar to 0.07. For the given runs, this transition to a wave-dominated regime can also be seemingly described by simply comparing the timescales 1/N and tau(eta), the latter being the Kolmogorov timescale based on the mean kinetic energy dissipation. Due to the known anisotropy induced by RaS, we consider separately the motion in the horizontal and vertical directions. In the regime N tau(eta) < 1, acceleration statistics exhibit well known characteristics of isotropic turbulence in both directions, such as probability density functions with wide tails and acceleration variance approximately scaling as per Kolmogorov's theory. In contrast for N tau(eta )> 1, they behave very differently, experiencing the direct influence of the imposed rotation and stratification. On the other hand, the Lagrangian velocity statistics exhibit visible anisotropy for all runs; nevertheless the degree of anisotropy becomes very strong in the regime N tau(eta) > 1. We observe that in the regime N tau(eta )< 1, rotation enhances the mean-square displacements in horizontal planes in the ballistic regime at short times but suppresses them in the diffusive regime at longer times. This suppression of the horizontal displacements becomes stronger in the regime N tau(eta) > 1, with no clear diffusive behavior. In contrast, the displacements in the vertical direction are always reduced. This inhibition is extremely strong in the N tau(eta )> 1 regime, leading to a scenario where particles almost appear to be trapped in horizontal planes.\nScheda prodotto non validato\nAttenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo\nTitolo: Single-particle Lagrangian statistics from direct numerical simulations of rotating-stratified turbulence Autori: Data di pubblicazione: 2020 Rivista: Handle: http://hdl.handle.net/20.500.11770/305763 Appare nelle tipologie: 1.1 Articolo in rivista", "pred_label": "__label__POS", "pred_score_pos": 0.8872202634811401}
{"content": "Tax laws and regulations can be a minefield of ever-changing information. Is a tax refund considered income that you have to report on the following year’s tax return?\nWhat is a tax refund?\nThe IRS collects income taxes each year. A tax refund is simply “a return of money paid that is more than what is actually owed for taxes,” according to\nMerriam-Webster.\nRegular employees will have taxes deducted from each paycheck based on how they fill out their Form W-4. Often, this can lead to overpaying on their taxes, which results in a refund. Self-employed individuals may also receive a tax refund due to overestimating their quarterly tax payments throughout the fiscal year.\nHaving a professional prepare your taxes may help avoid missed deductions, overpayment, and other issues.\nMany Americans like receiving a tax refund in April. However, getting a refund means that you’ve been loaning your money to the federal government. Some people prefer to overpay to avoid the risk of underpaying and owing money at the end of the year.\nThe IRS states that over 90 percent of refunds are issued within 21 days of processing a tax return. Some taxpayers elect to receive a paper check for the refund. However, around eight in ten people choose e-file and receive a direct deposit. The federal government issued nearly 122 million tax refunds for fiscal 2019 totaling $452 billion.\nIs a tax refund considered income?\nIt can be confusing to determine exactly what the IRS categorizes as taxable income.\nA tax refund on your federal income tax isn't considered income. Taxpayers don't need to worry about paying more taxes on the refund they received since it's technically the taxpayer’s money to begin with.\nThe refunds you receive from your state income tax returns may be considered income. It depends on whether you deducted state and local income taxes in your tax returns the previous year.\nUsing a standard deduction instead of an itemized one with deductions for state and local income taxes means that the refund isn't counted as income.\nIs a tax refund taxable?\nThe IRS doesn't require you to report your federal tax refund as taxable income. However, the rules are different for state income taxes.\nIf you elected to take an itemized deduction on your taxes the previous year, part or all of that refund may need to be reported as income the following year. Individuals can find out information for their specific situation on the IRS website.\nIf you didn't itemize your deductions and took a standard deduction, the resulting tax refund isn't taxable by the government. Another factor to recognize is that if you deducted state and local sales tax instead of income tax, your tax refund isn't taxable, according to H&R Block.\nWhen do you pay taxes on a tax refund?\nFor your state income tax refund, any taxes that you owe will be due the tax year immediately following the year the refund was issued. So, if you received a state income tax refund for 2019, you may need to report the refund as income on your 2020 tax returns.", "pred_label": "__label__POS", "pred_score_pos": 0.9353961944580078}
{"content": "By Niharika Yadav\nThe morning of 1st February witnessed the presentation of the Interim Budget 2019. Amidst the clamor of members of the 16th Lok Sabha, Interim Finance Minister Piyush Goyal began by thedeclaration – “India is solidly back on track.”[1] The statement was a euphemism for all the table-banging, chest thumping and bold proclamations that were underway in Mr. Goyal’s ravishing budget speech. The government broke conventions as it did not just target constituencies of swing voters, but also meddled with income tax to assuage them. While twitching the indirect taxation had been a common trend amongst past interim budgets, a change in direct taxation had not been observed before. This was because the budget was implemented only for a short duration before re-elections.\nThe government announced the Pradhan Mantri Kisan Samman Nidhi under which farmers holding less than 2 hectares of land, would be provided direct income support of Rs. 6,000 per year. Among chants of “Jai Kisan”, the FM highlighted that the government aimed to target about 12 crore small and marginal farmers through the same. It proposed the allocation of not just Rs. 75,000 crore for the current year (FY 2019-20) but also Rs. 20,000 crore in the revised estimates of previous year’s (FY 2017-18) budget.\nThe FM hailed this announcement as a culminating step by the government to uplift the farmers. He reminded the listeners about the rise in MSP by 50%, issuance of soil health cards and other pro-farmer initiatives taken up by the govt. However, opposition claimed that the measure was too insignificant to lead to any tangible benefit. Politician Yogendra Yadav went on to call the measure ‘an insult to the injury of farmers’. He said that the Telangana Govt., on whoseschemes this measure was modelled after, had promised Rs. 10,000 crore per hectare to the farmers whereas this scheme allowed for Rs. 6,000 per farmer which turned out to be Rs. 3 per farming family per day – an amount that was too tiny to even buy a cup of tea. Moreover, the announcement to implement the scheme retrospectively and to meddle with the balance sheet of FY 2017-28 irked various analysts. They believed that the government overstepped its bounds in doing so as it didn’t follow the convention of an interim budget.\nThe government also announced 2% interest subvention for animal husbandry and fishery farmers provided they availed loans through the Kisan Credit Card scheme. A healthy credit culture was also incentivised in the budget as it allowed an additional 3% subvention in case of timely repayment of these loans.\nThis scheme was further expanded to include farmers who faced natural calamities. As 2% interest subvention already existed for the first year of rescheduling of their loans, the govt. proposed to allow this benefit for the entire period of disaster along with an additional 3% for timely repayment of loans.\nThe government sought to target communities that hadn’t received appropriate policy interest. It established a committee under NITI Aayog to identify De-notified, Nomadic and Semi-Nomadic communities and proposed other measures to ensure their development. Further, the government increased the allocation for North-East by 21% to Rs. 58,166 crore in FY 2019-20. For workers above the age of 60 in the unorganised sector, the government launched the Pradhan Mantri Shram Yogi Mandhan, which provided a monthly pension Rs. 3,000 per month, with contributions of Rs. 100 per month. While this was assured for workers joiningat the age of 29, the government mandated contributions of a mere Rs. 55 per year for workers joining the workforce at the age of 18.\nThe FM dodged the raging topic of unemployment amidst the outcry of fellow Lok Sabha members, by claiming that strong GDP growth and formalisation in the past 4 years implied job creation. He refused to engage with the controversy regarding methods of unemployment calculation, and relied on EPFO membership statistics that indicated an increase of about 2 crore people.\nCharting the territories of direct taxation, the FM announced full tax rebate to individual taxpayers earning taxable annual income of up to Rs. 5 lakh under Section 87A. The FM went on to claim that this measure would benefit about 3 crore middle income consumers and would provide benefit of Rs. 18,500 crore. Analysts claimed that these figures were highly exaggerated as they included individuals having gross income greater than Rs. 5 lakh who invested in provident funds, specified savings, education loans, National Pension Scheme contributions, medical insurances and other deductions. Various analysts were sceptical of this assumption as bringing an income of Rs. 7 lakh down to Rs. 5 lakh by indulging in these deductions would be unrealistic for an individual taxpayer.\nTax benefits for the salaried middle class included a hike in standard deductions from Rs. 40,000 to Rs. 50,000. For individuals occupying two households, income tax on the second self-occupied house was exempted. This aimed to benefit various middle income earners who had two households on account for care for parents, children’s education and jobs. Moreover, the threshold for TDS on interest earned through bank/post office deposits was raised from Rs. 10,000 to Rs. 40,000.\nThe budget leapt beyond its fiscal deficit target of 3.1% for FY 2019-20 by pegging it at 3.4%. Analysts have differing views on how this will impact the fiscal health of the government. Arvind Chari, Head Fixed Income & Alternatives, Quantum Advisors, categorised the budget to be inflationary in nature as overall expenditures saw a 13% hike. This was majorly due to the income support allocations for the farmers. Moreover, many claimed that the FM’s expectation of revenue through GST collections was overestimated, and so were his estimates of growth in taxation rate of about 18% for FY 19-20. Data revealed a fluctuation in GST collections from May 2018 with collections from November dropping to Rs. 97,00 crore in November 2018 and Rs. 94,000 crore in December as compared to Rs.1 lakh crore in October.[2] In the lack of a clear upward trend in collections, the market expected the fiscal and revenue targets to be moderate. Chari claimed that this could affect the bond market negatively. He further added, “The RBI and the MPC may view the fiscal compromise, aggressive assumptions and the potential inflationary nature of the budget and leave interest rates unchanged.”\nHowever, Revenue Secretary Ajay Bhushan Pandey brushed aside these claims boldly. He maintained that GST is going through a phase of stabilization and despite the recent implementation, revenue trends are encouraging. Moreover, he said that due to a wide increase in tax base under the Modi government around 1 crore people have been added to the list of taxpayers. This increase along with an increase in corporate tax collection was sufficient to account for (a) loss of revenue, or (b) increase in expenditure by the government, and ensure that the fiscal map of the coming year was realistic.[3] Opposition also pointed out that the Rs. 7 lakh crore of market borrowing in this budget, which is higher than the Rs. 5.71 lakh crore estimated for this year, can disrupt the fiscal balance. However, Pandey cleared that only about Rs. 4 lakh crore of the total was for financing the fiscal deficit, while the rest was meant for repayment of past loans.\nThe budget can prove to be either the\nAaakhri Jumlaa, as Rahul Gandhi crudely put, or a pro-growth budget maintaining fiscal prudence. Only the upcoming year can reveal which of these possibilities stands corrected. Till then, however, we must await the nation’s verdict on who it will invite to form the next government.\nSources:", "pred_label": "__label__POS", "pred_score_pos": 0.5212885141372681}
{"content": "Homeowners and renters continue to be impacted by the coronavirus pandemic, as the economy has not yet fully recovered. On Thursday, August 27, the Federal Housing Finance Agency (FHFA) and Department of Housing and Urban Development (HUD) announced that Fannie Mae and Freddie Mac have extended the moratoriums on single-family foreclosures until December 31. The moratoriums cover some evictions as well. Previously, these moratoriums were set to expire on August 31.\nThe third extension of the moratorium was issued independent of the CARES Act passed by Congress in March. This legislation provided a 60-day moratorium on foreclosures and evictions on properties financed by federally backed mortgages. The FHFA requires direct mortgage servicers to halt all new foreclosure actions and suspend those in process. This is intended to help homeowners who have faced financial hardship due to the COVID-19 pandemic.\nHow Will Homeowners Be Affected?\nAccording to FHFA director Mark Calabria, the move protects close to 28 million homeowners. Designed to keep borrowers in their homes during this difficult time, the moratorium extension provides benefits such as:\nRelief for about 28 million renters left out of federally mandated relief options. Homeowners struggling to pay their mortgage or facing possible foreclosure may have options to obtain assistance during the national emergency. Homeowners with a Federal Housing Administration (FHA) insured mortgage can request an extension of forbearance for up to a year. Waiving of penalties and late fees for delayed mortgage payments. Lump sum payments will not be required when the forbearance period ends. A qualified principal residents indebtedness exclusion, for up to $2 million (for married couples), of forgiven debt. This tax break is temporary unless Congress renews it.\nHowever, the moratorium doesn’t apply to homeowners with private mortgages; separate moratoriums may apply to borrowers working with private lenders.\nDoes It Do Enough?\nHousing advocates insist Americans need more relief than the extension provides. For example, the National Housing Conference has called on lawmakers to extend relief to up to 40 million renters at risk of being evicted. A letter to Congress submitted by 31 housing organizations requested protections for property owners and renters in the next stimulus package. According to the letter, COVID-19-impacted renters owe an estimated $25 billion in back rent and up to $70 billion by year’s end, potentially putting tens of millions at risk of eviction and financial ruin.\nIn July, foreclosure filings were down 83% from a year ago, according to ATTOM Data Solutions, but with economic fears and more people losing their jobs, some experts predict the numbers to rise in 2021. The current stalemate in Washington over the next relief package doesn’t help. House Democrats passed the $3 trillion HEROES Act in May. It would provide $175 billion in rent and mortgage assistance, while Senate Republicans have introduced their own stimulus proposal, which includes several smaller bills.\nNonetheless, the moratoriums on evictions and foreclosures are much needed. The results of a Mortgage Bankers Association survey in August led the organization to estimate 3.6 million homeowners are receiving forbearance and identify a spike in delinquencies for mortgage loans on one- to four-unit residential properties.\nContact OakTree Law for Mortgage Help\nIf you’re facing financial difficulties, foreclosure, or bankruptcy, the Los Angeles and Orange County bankruptcy attorneys at OakTree Law can help. Our law firm is open during the coronavirus pandemic to assist clients, conducting consultations by phone and filing cases with the courts. To request a free evaluation, contact us online or call 562-219-2979 today!", "pred_label": "__label__POS", "pred_score_pos": 0.598242998123169}
{"content": "Chronic lymphocytic leukemia (CLL) is a malignant, chronic lymphoproliferative disorder characterized by proliferation and accumulation of monoclonal B-cells in the bone marrow, peripheral blood, lymph nodes, liver and spleen.\nIt is the most common form of adult leukemia in the Western world but rare in Asians.\nExact etiology is unknown but usually associated with genetic aberrations and lesions.\nDiabetes is a key risk factor for heart failure (HF), which is the leading cause of hospitalization in patients with or without diabetes. SGLT-2* inhibitors (SGLT-2is) have been shown to reduce the risk of hospitalization for HF (HHF) regardless of the presence or absence of diabetes.", "pred_label": "__label__POS", "pred_score_pos": 0.8582645058631897}
{"content": "Magnesium Citrate 250mg\nIt is estimated that 1 in 2 Americans have inadequate magnesium dietary intake. Magnesium is needed for 300+ biochemical reactions. It also helps maintain normal muscle and nerve function, keep heart rhythm steady, support a healthy immune system, support energy production, relax your muscles.**\nMagnesium\n(as magnesium citrate)250mg\nOur Certifications\nDISCLAIMER: ** These statements have not been evaluated by the Food and Drug Administration.\nThis product is not intended to diagnose, treat, cure or prevent any disease.", "pred_label": "__label__POS", "pred_score_pos": 0.700008749961853}
{"content": "What's your value proposition? Did you know a value proposition is made of two parts. The first is a promise of the value your business will deliver to your customers. The second part is the customer ́s perception about how that value will be received.\nFor many B2B marketers, defining exactly what their “value” is can be a daunting task. This is why we recommend referencing “The B2B Elements of Value” chart. The chart was created by\nBain & Company in 2018 and is based on a study carried out by the firm into what matters most to B2B buyers.\nThis chart breaks down the different elements that can play a part in an organisation’s value proposition. To make it more digestible, the elements have been broken down into 5 categories, each with their own subcategories.\nTo help you get the most out of the model, we’ve created a short list of questions you can answer to get a clearer understanding of your organisation’s value.\nInspirational Value\nVision - What is your company’s vision for its customers and the world?\nHope - How does your company inspire hope for a brighter future?\nIndividual Value\n1. Career -\nNetwork expansion - How does your business help someone expand their professional network?\nMarketability - How does your business help someone become a more attractive candidate in the job market?\nReputational assurance - How does your business boost and safeguard the reputation of a client or customer?\n2. Personal -\nDesign & aesthetics - How does your product or service’s design add value to a client or customer?\nGrowth & development - How does your business aid a client or customer in their career growth and development?\nReduced anxiety - How does your business alleviate worries and fears for clients and customers?\nEase of Doing Business Value\n1. Productivity -\nTime savings - How does your offering save clients time?\nReduced effort - How does your offering enable your clients to use fewer resources to complete a task?\nDecreased hassles - How does your offering reduce common customer pain points?\nOrganisation - How does your offering empower your clients to become more organised?\nConnection - How does your offering improve the connection between departments in a client’s organisation?\nIntegration - How easy is it to integrate your offering into established business practices?\n2. Access -\nVariety - Do you have one offering or many? What are the benefits of your chosen approach?\nConfigurability - Is your offering customisable or not?\n3. Relationship -\nResponsiveness - How quickly can your team respond to queries?\nExpertise - How knowledgeable is your team regarding the industry and offering?\nCommitment - How dedicated is your team in helping clients achieve their desired outcomes?\nStability - How stable is your business within the marketplace and current economic climate?\nRisk reduction - Does your offering reduce risks for your clients?\nReach - Does your offering allow your clients to improve their reach?\nFlexibility - Is your offering a flexible solution?\nComponent quality - Are the various elements of your offerings enhancing your client’s own offerings?\nFunctional Value\n1. Economic -\nImproved top-line - How does your offering improve a client’s business growth?\nCost reduction - How does your offering allow your clients to cut costs or save money?\n2. Performance -\nProduct quality - Is your offering exceeding the expected quality standards within the marketplace?\nScalability - How easy is it to scale or roll out your solution within larger, global organisations or different departments within smaller organisations?\nInnovation - How is your offering ahead of the curve in comparison to others that are available?\nTable Stakes\nMeeting specifications - Does your offering meet the specifications your target clients have in mind?\nAcceptable price - Is the price of your offering acceptable within the marketplace and reasonable for the value demonstrated?\nEthical standards - Does your organisation demonstrate ethical standards that are in line with those of your target clients?\n---\nWould your organisation like to refine its value proposition to make a bigger impact?\nGet in touch with Philip Martin to discover how DMA Partners can help you use the elements mentioned in this article to strengthen your position in your industry:\nphilip.martin@dma-partners.com.", "pred_label": "__label__POS", "pred_score_pos": 0.9966995716094971}
{"content": "This paper estimates the importance of temptation (Gul and Pesendorfer, 2001) for consumption smoothing and asset accumulation in a structural life-cycle model. We use two complementary estimation strategies: first, we estimate the Euler equation of this model; and second we match liquid and illiquid wealth accumulation using the Method of Simulated Moments. We find that the utility cost of temptation is one-quarter of the utility benefit of consumption. Further, we show that allowing for temptation is crucial for correctly estimating the elasticity of intertemporal substitution: estimates of the EIS are substantially higher than without temptation. Finally, our Method of Simulated Moments estimation is able to match well the life-cycle accumulation profiles for both liquid and illiquid wealth only if temptation is part of the preference specification. Our findings on the importance of temptation are robust to the different estimation strategies.", "pred_label": "__label__POS", "pred_score_pos": 0.684672474861145}
{"content": "Research and reports UNICEF’s work is grounded in empirical data, rigorous research and thoughtful analysis. Latest publications Public finance for children\nUNICEF and the Ministry of Finance and Planning of the United Republic of Tanzania have been jointly analyzing public expenditure on children since 2016. The 2018 edition of budget briefs is the second in the series.\nThese briefs focus on analyzing and monitoring budget allocations in key social sectors like health, education, WASH and HIV/AIDS, especially since these affect children.\nThey provide an overview of the public expenditure, and emphasize on critical dimensions such as spending trends, execution performance, equity aspects, fiscal decentralization, and sources of funding.\nData for children Publications catalogues\nThe Knowledge for Children in Africa publication catalogue collects studies and reports that are being produced on the continent, representing the collective knowledge supported by UNICEF.\nThe aim of the catalogue is to create an increased demand for products that will be produced by UNICEF over the coming year, and to provide timely information on the knowledge UNICEF and partners are generating in Africa.\nThe availability of knowledge and evidence is crucial for informing policies and programmes to ensure they have an impact on children and contribute to the realization of children’s rights.", "pred_label": "__label__POS", "pred_score_pos": 0.5372115969657898}
{"content": "In 2018, the Upjohn Institute launched an initiative to explore how communities can create broadly shared prosperity by helping residents get and keep good jobs. Our initiative brings together two areas of Institute expertise: place-based scholarships that help local residents increase their education, and economic development policies, such as tax incentives and customized business services, that directly target local job creation.\nWe link strategies that support firms in creating good jobs with strategies that give residents the skills and supports needed to work in those jobs. Our approach focuses on strategies communities can\nthemselves deploy to achieve these ends. While we recognize the importance of federal and state support in helping communities achieve these objectives, we believe locally led efforts are vital in laying the groundwork necessary to create vibrant local economies that benefit everyone.\nIn this effort, the Institute benefits from growing linkages between its research and operations activities. In addition to the research on employment policies it has conducted for three-quarters of a century, the Institute administers federal and state workforce training programs in a four-county region in Southwest Michigan. We also advise communities in our backyard and throughout the nation on best practices in areas such as economic development, workforce/talent development, and the design of place-based scholarships.\nThe Institute collaborates with the Kalamazoo Promise, the first of the current generation of place-based scholarships, and the City of Kalamazoo, which is engaged in innovative place-based development through the Foundation for Excellence and Shared Prosperity Kalamazoo. The Upjohn Institute works with the city and the Kalamazoo Promise around best practices, data systems, and evaluation, and aims to use what we learn locally to inform other small- to mid-sized cities facing similar challenges.\nThe research initiative is led by three co-directors with the support of an internal steering committee, a policy advisory committee, and a research affiliate network.", "pred_label": "__label__POS", "pred_score_pos": 0.930557370185852}
{"content": "We appreciate the thoughtful comments of Rath and associates and agree with their assessment of the limitations of our study. We intended to examine the diagnostic yield and therapeutic benefit of nonquantitative polymerase chain reaction (PCR) in the management of anterior uveitis. Our data suggest that under these conditions PCR has limited utility. We agree that quantitative PCR can have greater utility in select cases. We also wish to point out that complications, even severe ones, can occur. Given our data, we cannot advocate routine use of nonquantitative PCR for anterior uveitis.", "pred_label": "__label__POS", "pred_score_pos": 0.7228608131408691}
{"content": "Information for reviewers Additional Guidance for Reviewers on mitigating against how COVID-19 has impacted applicants and the risk of projects needing to be abandoned for grants that were already awarded/ongoing before the COVID-19 pandemic and accounting for the unknown impacts of COVID-19 in any new application\nUKRI recognises that the COVID-19 pandemic has caused major interruptions and disruptions across our communities and are committed to ensuring that individual applicants and their wider team, including partners and networks, are not penalised for any disruption to their career(s) such as breaks and delays, disruptive working patterns and conditions, the loss of on-going work, and role changes that may have been caused by the pandemic.\nWhen undertaking your assessment of the research project, you should consider the unequal impacts of the impact that COVID-19 related disruption might have had on the track record and career development of those individuals included in the proposal, and you should focus on the capability of the applicant and their wider team to deliver the research they are proposing.\nUKRI acknowledges that it is a challenge for applicants to determine the future impacts of COVID-19 while the pandemic continues to evolve. Applicants have been advised that their applications should be based on the information available at the point of submission and, if applicable, the known application specific impacts of COVID-19 should be accounted for. Where known impacts have occurred, these should have been highlighted in the application, including the assumptions/information at the point of submission. Applicants were not required to include contingency plans for the potential impacts of COVID-19. Requests for travel both domestically and internationally could be included in accordance to the relevant scheme guidelines, noting the above advice.\nWhen undertaking your assessment of the research project you should assess the project as written, noting that any changes that the project might require in the future, which arise from the COVID-19 pandemic and these will be resolved as a post-award issue by UKRI if the project is successful. Potential complications related to COVID-19 should not affect your assessment or the score you give the project.\nPlease also refer to the UKRI Principles of Assessment and Decision Making documentation.\nAll applications for research grants undergo scientific assessment of research quality by UK and overseas experts in the field from academia, government or industry.\nThis assessment considers how applications meet the criteria for:\nScientific excellence Strategic relevance Industrial and stakeholder relevance Economic and social impact Timeliness and promise Value for money Staff training potential of the project.\nReviewers should not use journal-based metrics, such as Journal Impact Factors, as a surrogate measure of the quality of individual research articles, to assess an individual scientist’s contributions. This is in line with our commitment to the San Francisco Declaration on Research Assessment (DORA).\nFellowship reviewers\nYou may need to download additional plug-ins to open this file.\nGrant reviewers\nYou may need to download additional plug-ins to open this file.\nKeywords\nThe spreadsheet below contains a revised list of keywords launched in December 2008.\nYou may need to download additional plug-ins to open this file.", "pred_label": "__label__POS", "pred_score_pos": 0.813347578048706}
{"content": "Prominent sociopsychological approaches interpret collective victimhood as inseparable, central characteristic of societies involved in intractable conflicts. Victimhood is broadly perceived as an essential conflict‐supportive belief also in other disciplines. In the context of Israel, there is a cross‐disciplinary consensus that collective victimhood is the country’s foundational identity. This project argues that states’ employment of this theme changes and is context dependent. It discusses under what conditions Israel’s political elites incorporate victim narratives towards armed conflicts. It examines public communication during the 2012 Operation Pillar of Defense (OPD) and the Yom Kippur war of 1973 (YKW). Employing a modified method of narrative conceptualization analysis, the research demonstrates that victim narratives were used almost twice as much during OPD than during YKW.", "pred_label": "__label__POS", "pred_score_pos": 0.6702269315719604}
{"content": "Washington D.C., Nov. 2, 2020 —\nThe Securities and Exchange Commission’s Division of Enforcement issued its annual report for fiscal year 2020 today. The report provides a comprehensive view of the Division’s accomplishments over the past year, discusses significant actions and key areas of strategic change, and details the Division’s COVID-19-related enforcement efforts.\n“This year’s report highlights Enforcement’s extraordinary efforts across the country to identify wrongdoing and take meaningful action to protect American investors from misconduct, including in the face of the many challenges imposed by COVID-19,” said SEC Chairman Jay Clayton. “In addition to discussing the core types of cases brought by the Commission, the report shows how Enforcement took action at the onset of the global pandemic against wrongdoers who sought to take advantage of the uncertainty and volatility in the markets. The report also illustrates our strong commitment to the Commission’s whistleblower program, as we devoted additional resources, achieved significant milestones in the total amount awarded and number of individuals awarded, implemented process improvements and adopted Commission rules designed to improve transparency, clarity and efficiency for whistleblowers. The dedicated women and men of Enforcement, in our headquarters and 11 regional offices, demonstrated their unwavering commitment to protect investors and our markets.”\n“Fiscal year 2020 was a year filled with extraordinary challenges that impacted us all in countless ways. I am incredibly proud of the exceptional work of my colleagues in the face of these challenges and I am pleased to share the results of that work in our annual report,” said Stephanie Avakian, Director of the SEC’s Division of Enforcement.\nThis year’s report discusses how the Division took affirmative steps to prevent potential fraud related to the COVID-19 pandemic and bring actions against wrongdoers who attempted to capitalize on it, while at the same time continuing to focus on the multitude of existing and new non-COVID-related enforcement issues arising in the normal course. The report also describes strategic changes the Division implemented to improve its operations in several key areas, including by implementing a number of efficiencies in the whistleblower program and increasing the pace of investigations. Additionally, as in prior years, the report highlights the Division’s commitment to core principles such as protection of retail investors, focus on individual accountability, and imposition of remedies that most effectively further enforcement goals.\nIn fiscal year 2020, the SEC brought a diverse mix of 715 enforcement actions, including 405 standalone actions. These actions addressed a broad range of significant issues, including issuer disclosure and accounting violations; foreign bribery; investment advisory issues; securities offerings; market manipulation; insider trading; and broker-dealer misconduct. Through these actions, the SEC obtained judgments and orders totaling approximately $4.68 billion in disgorgement and penalties – a record amount for the Commission – and returned more than $600 million to harmed investors. Significantly, through the Division’s efforts, the SEC awarded a record $175 million to 39 whistleblowers in fiscal year 2020, both the highest dollar amount and the highest number of individuals awarded in any fiscal year.", "pred_label": "__label__POS", "pred_score_pos": 0.8947604894638062}
{"content": "In “The New Rules of Retail,” industry gurus Robin Lewis and Michael Dart explained how unprecedented consumer power, enabled by technology and globalization, is revolutionizing retail. They warned that survival in these dynamic times called for a business model based on three distinct competencies: preemptive, perpetual distribution; a neurological customer connection; and total control of the value chain.\nIn the years since that book published, many of their predictions have come true. Now, they revisit timeless case studies like Ralph Lauren and Sears, as well as new additions like Trader Joe’s, Lululemon, and Warby Parker, to assess how retailers must continue to evolve in the era of e-commerce, data mining, and tiered distribution.\nThey also identify the five current trends that are currently driving consumer demand, including technology integration and channel consolidation, as exemplified by Jeff Bezos at Amazon. This is a fully revised and updated guide from two proven retail prognosticators.\nTo purchase a copy or to learn more, click HERE.", "pred_label": "__label__POS", "pred_score_pos": 0.59644615650177}
{"content": "Cytosolic phospholipase A(2) (cPLA(2)) group IValpha is a critical enzyme involved in the liberation of arachidonic acid from cellular membranes. cPLA(2)(-/-) mice have reduced allergen-induced bronchoconstriction and bronchial hyperresponsiveness. The goal of this study was to investigate polymorphisms of the (CA)(n) and (T)(n) microsatellites and surrounding regions in the cPLA(2)alpha gene promoter. We analysed the cPLA(2) promoter regions containing (CA)(n) and (T)(n) repeats in 87 patients with severe asthma and in 48 control subjects by bidirectional sequencing. Functional studies were performed utilizing reporter genes derived from subjects with varying numbers of these repeats, and on constructs with a series of deletions. We found that the (CA)(n) and (T)(n) regions are polymorphic and that constructs with CA or T repeats or CA and T repeats deleted revealed, respectively, a 41.8 +/- 7%, 22.3 +/- 5% and 100 +/- 20% increase in reporter gene activity. A lower number of CA or T repeats caused higher cPLA(2) promoter luciferase activity. The group of shorter alleles of the (CA)(n) microsatellite region (n = 12-18) (P(cor) = 0.00006), and the group of shorter alleles of (T)(n) repeats region (n = 17-38) (P(cor) = 0.0039) occurred significantly more often in patients with severe asthma. We also found novel SNPs in positions -292 C > G, -185 A > C, -180 T > C and -165 A > C. Two of them were associated with the severe asthma phenotype: -180T allele (P(cor) = 0.03996) and -185 A allele (P(cor) = 0.03966). These results demonstrate that (CA)(n) and (T)(n) repeats may have an influence on cPLA(2) transcription which might play a role in severe asthma pathogenesis.", "pred_label": "__label__POS", "pred_score_pos": 0.5402576923370361}
{"content": "“The customer is king” is an inspirational quote that has been around for a while now, and for good reason. An American Express survey claims that up to 68% of customers reported to have the will to spend more for the company that delivers excellent customer service. One of the most prominent methods to offer exceptional service and customer interactions is by having a thorough understanding of your customer. Data collection and analysis has helped businesses understand their customers better. However, it must be noted that this data collection and analysis had been a common practice even before the new-age technologies helped the cause.\nThe advent of advanced technologies such as big data and analytics, AI, ML, and advanced robotics, has transformed customer interactions, and real-time tracking became easier. However, even now, data accumulation remains an intrusive process that largely involves queries and physical feedback. In the digital age, the ultimate customer experience will depend on proactive and not reactive measures.\nTo approach customer experience and customer interactions in a fundamentally transformed manner, businesses are starting to experiment with various innovations and emergent technologies of data collection and analysis, such as AR/VR and cognitive computing. More recently, facial expressions and emotions are being analyzed for immediate feedback indexing rather than relying on traditional channels of feedback.\nThe Need for Facial Expression Recognition\nThere is a wide spectrum of expressions and micro-expressions that can denote specific emotional responses. So, the potential to register the facial movements and analyze them against a set benchmark data is quite huge. Some tests have even reported an astounding accuracy rate of 95% which can be considered impressive by any measure.\nThe technological innovations have provided us with better and more efficient measures that can be utilized to record customer feedback. So far, customer feedback collection has depended on tried and tested traditional measures such as filling out forms, evaluating services and experiences on a scale of five or 10, pressing buttons on consoles, or responding to questions asked by providers or aggregators. However, this approach is progressively turning redundant and underproductive as consumer endpoints drastically increase in number. Therefore, businesses are trying to collect data from facial expressions and reactions, and evaluate their products, services, and overall customer experience.\nOne of the primary aspects of facial expression recognition is that it offers a non-intrusive alternative to asking for customer feedback. On the other hand, filling out surveys or rating experiences physically may be considered a tedious task by customers, thereby affecting the ratings. Additionally, facial expressions are reactionary and, in most cases, involuntary. This ensures that the true reaction or feedback is registered based on the experiences delivered thereby ensuring a higher authenticity of customer data.\nThe Benefits\nEvaluating feedback is an integral process of product and service enhancements. They are also crucial for marketing campaigns. It is therefore paramount for businesses to gain as much authentic insight as possible. As mentioned, facial expressions are the most authentic reactions and hence a reliable form of feedback and recognizing facial expressions for feedback also remarkably reduces the time taken compared to the survey model of feedback. It also makes it easier for customers as they do not need to consider giving feedback as a task.\nFacial expressions are the most authentic reactions and hence a reliable form of feedback and recognizing facial expressions for feedback also remarkably reduces the time taken compared to the survey model of feedback.\nIn this highly competitive market, customer experience is fast becoming the key differentiator. It is therefore important for businesses to be proactive in their approach and gain feedback from facial expressions. While facial expression recognition-based feedback cannot be as exhaustive as a survey-form feedback, the technique is in its nascence and in conjunction with emergent technologies and smarter devices; it will be the foremost form of data collection in the future owing to its non-intrusiveness and other associated advantages.\nAnother aspect of consideration is that this process offers real-time insights without any risk of data security. In the long run, this method will show remarkable progress by improving performance while reducing cost and time.\nThe Way Forward\nTechnology, however, should not be used for technology’s sake. Ultimately the outcome is to provide an exceptional customer experience leveraging the insights generated by the recorded data. This empowers organizations to provide improved services that ultimately enhances the customer experience manifold.\nWith the ongoing COVID-19 pandemic, leveraging technology to enable businesses to function has become the new normal. In this paradigm, advancements in facial expression recognition have the potential to revolutionize the interaction between businesses and customers. And on a fast track to a digital future, this promises a definite way to elevate customer experience to newer heights.", "pred_label": "__label__POS", "pred_score_pos": 0.8070719242095947}
{"content": "Blockchain has been taking the digital world by storm. With some myriad applications from real estate to financial transactions, the term refers to the process of creating a ‘chain of blocks’ – within which a series of encrypted transactions are embedded, creating a ‘ledger’ of transactions. The entities (individuals or interfaces, as the case may be) responsible for creating a block are called nodes.\nIt is essential to understand that a block once added to the existing chain is permanently accessible – to be shared/available for use by other nodes. Moreover, every node must adhere to specific storage standards for transaction data and have a complete copy of the data. This consolidated record forms the ‘distributed ledger’.\nSeveral rules define how nodes can exchange Blockchain information, and mathematical rules – unanimously determined by all nodes involved – control the integrity of data. This ensures that all transactions are validated and no valid transaction can be added more than once. Security is further fortified via cryptography – implemented through a combination of public and private keys. The relevant nodes verify the transactions to avoid double accounting.\nIn addition, access to the Blockchain network can be classified as either permissioned or permission-less – in the first scenario, only certain entities can function as nodes and gain access to the Blockchain network. On the other hand, permission-less Blockchain technology adds a measure of flexibility. With no restriction on who can perform the role of the node, validating the transactions and adding the instructions to the ledger becomes a more open process.\nThe Blockchain’s dynamic capabilities make it all the more appealing – with a provision to add automated, programmable outcomes based on an event. For instance, payment can be triggered if the interest payment date has been reached for a particular bond. Within the world of Fintech, therefore, the technology can be leveraged in multiple ways – here are three crucial use cases that illustrate the power of Blockchain.\nUse case 1 – Simplifying equity settlement with a Blockchain-based network\nOnce investors have posted the orders to the trading venue, the orders are matched and the trades are sent to the Blockchain network for validation and addition to the ledger. The differentiating factor is that the transaction is validated by brokers on both sides – marking the transactions as “settled” and making ledger additions without further disputes.\nBesides enabling the use of bitcoin, Blockchain also stores a holistic settled transaction history for related equities, along with the cash and securities ledger. Brokers, trading venue, and depository can be key stakeholders – checking incoming transactions with parameters like eligibility, position checks, KYC, and so on. The system is supplemented by a regulator node, with overarching access and rights akin to the oversight function.\nThe technology also performs a preemptive role – avoiding ‘double spend’ issue where a duplicate transaction might be sent to the system at the same time. With a consensus-based verification model, the latest state of the ledger can be isolated and only one transaction is accepted if two with the same details arrive simultaneously.\nAlongside access to bitcoin, Blockchain network is restricted only to key stakeholders within a particular settlement. In fact, this boosts transaction throughput – currently, one of the main drawbacks plaguing Blockchain technology in its present form.\nHow will the Broker or Dealer be impacted?\nAll the brokers can actively contribute to the final settlement – performing asset availability checks and eliminating transaction rerouting needs through a specific clearing member. However, as the transactions are settled in the gross format rather than net, it may create intra-day liquidity pressure.\nOn the other hand, this can be offset by a reduction in collateral pressure. Regulatory reporting pressure is also significantly eased as the regulator now gets better access to the ledger details – till the end investor level.\nUse case 2 – Decentralizing asset ledgers within an enterprise\nThe typical centralized asset ledger offers a few inherent advantages – like maintaining a single version of truth and a single point of control. Yet, there are certain crucial impediments, such as over-dependence on a monolithic system. A distributed asset ledger can significantly lessen reconciliation effort, as in the case of cross-border transactions.\nAsset ledgers can be decentralized through the implementation of the Blockchain technology. Internal systems form geography-agnostic nodes – validating inbound transactions for eligibility. Since only internal systems are allowed to be part of the Blockchain, the need for additional security features is minimized. This leads to a decrease in operational costs for running the Blockchain network, while increasing the speed of transaction processing.\nHow will the asset custodian respond?\nWith the shift to a distributed ledger, a custodian will be able to drive efficiency by performing as a global custodian – this is because the global as well the local custodian is consolidated in a single ledger. Further, it will provide a real-time, across-the-world view of risk exposures for proprietary/client trades. Finally, it will reduce redundancies in trade processing functions – such as multiple layers of validation or enrichment– once at the global and again at the local custodian level.\nUse case 3 – Integrating documentation frameworks within an enterprise\nIn a dynamic and constantly expanding regulatory landscape, the cost of upkeep for key documents keeps soaring in tandem – for storing signed documents and sharing them with key stakeholders, both internal and external. In a Blockchain-enabled scenario, all documents can be contained within a ledger and tagged to the key parties or signatories involved, for easy retrieval.\nIt is important to note that these nodes can be internal or external – therefore, an advanced cryptographic system needs to be in place to ensure secure transportation of documents between parties. Only certified nodes can post documents for addition within a Blockchain network or arrive at the new state of ledger through a common consensus, to avoid posting the same document again. Access to the documents will be further regulated via advanced encryption tools.\nHow can a bank’s KYC and document management systems benefit?\nSince the documents are centralized at the group level, it will reduce the cost of performing KYC checks. Duplication of KYC functions can be avoided – especially when a client of one subsidiary tries to avail services from another subsidiary. Finally, maintaining the documents in digitally accessible e-form ensures faster retrieval when compared to manual processes.\nReferences: Use Case 1: Oliver Wyman report on Blockchain – Blockchain-In-Capital-Markets Use Case 3: Very High level inputs from news regarding Mizuho and CTS", "pred_label": "__label__POS", "pred_score_pos": 0.9727767109870911}
{"content": "Restoration: Continuity\nContinuity, or Business Continuity, is the concept of maintaining the Institution’s most core-critical functions under compromised or limited conditions.\nContinuity assesses and prioritizes the programs, services, and systems that must remain operational under all circumstances. Subsequent continuity activities include detailed planning regarding the policies, plans, procedures, and resources needed to ensure continued operations.\nContinuity bridges the gap between response and recovery by focusing on those functions that need to stay online or become operational as soon as possible, even under temporary conditions.\nThe three main priorities for consideration toward continuity are:\nIdentify and restore critical facilities Identify and restore crucial functions Mobilize essential personnel\nFor example: A fire in the Registrar’s office during the first week of the semester requires the immediate evacuation of personnel. Fire crews respond and extinguish the fire, and Facilities Services makes every effort to prevent further water damage caused by fire suppression systems. These are considered response activities. The fire and water led to considerable damage that will take weeks to repair, but the office needs to resume operations immediately to avoid a lengthy disruption of service. Continuity plans address contingencies to temporarily relocate the Registrar’s office, reestablish a functional work space, restore critical information systems, and resume services.", "pred_label": "__label__POS", "pred_score_pos": 0.9998387694358826}
{"content": "en When infection and malignancy intersect in Rwanda: A diagnostic challenge in the tropics—Case Report Tuan, J.; Nkeshimana, M.; Masaisa, F.; Manirakiza, F.; Ruhangaza, D.; Murayire, J.; Mukanumviye, M.S; Kubwayo, A.P.; Niyigena, O.; Habanabakize, T.; Byukusenge, M.; Niyoyita, B.; Moise, I.S.; Niyotwambaza, J. & Kailani, L.Abstract\nKeywords\nCASE PRESENTATION: We describe a 38-year-old Rwandan male patient who presented to the hospital with a two-week history of left axillary lymphadenopathy, fever, weight loss, and one-year history of dysphagia. Lymph node fine needle aspirate was consistent with tuberculous lymphadenitis. Peripheral blood smear suggested a concomitant diagnosis of Acute Myeloid Leukemia (AML), which was confirmed by bone marrow biopsy. Although several cases of concurrent pulmonary tuberculosis and AML exist, fewer cases of concomitant tuberculous lymphadenitis and AML have been reported. CONCLUSION: This case highlights the need to keep a high suspicion for malignancy in a patient with lymphadenopathy, leukocytosis, and constitutional symptoms; at the same time, a coexisting opportunistic infection such as tuberculosis should not be overlooked in the tropical clinical setting. Tuberculous Lymphadenitis; Acute Myeloid Leukemia; Lymphadenopathy; Immune Reconstitution Inflammatory Syndrome; Fine-Needle Biopsy; Immunohistochemistry; Leukocytosis; Pulmonary Embolism; Splenomegaly", "pred_label": "__label__POS", "pred_score_pos": 0.7325127124786377}
{"content": "Conspiracy theorist\nEric Bahrt may be factually correct in both his recent letters concerning the polio vaccine. However, he has missed at least one important point. As I understand it, the vaccine delivered orally contains an attenuated virus, which stimulates an immune response without giving you polio. This attenuated virus may be passed from one person to another. Thus, although not everyone receives the vaccine, they may still benefit from the vaccination programme by “catching” the attenuated virus strain. This would explain why herd immunity may be achieved without necessarily vaccinating everyone.\nPerhaps more importantly, Mr Bahrt seemed to be implying in his first letter that vaccination is some kind of weird conspiracy, though I may have misunderstood him. It is not entirely clear precisely what he believes. Perhaps he might care to state his views explicitly.\nNIGEL WOODWARD", "pred_label": "__label__POS", "pred_score_pos": 0.8277486562728882}
{"content": "موارد\nKEY RISKS: The increased tensions between host communities and refugees could decrease social stability and undermine progress made to date under the LCRP.\nWhat is COVID-19?\nCOVID-19 is a disease caused by a new strain of coronavirus. ‘CO’ stands for corona, ‘VI’ for virus, and ‘D’ for disease.\nAs the Novel Coronavirus (COVID-19) continues to spread in an unpredictable manner it presents a growing risk to all stakeholders involved in food assistance, particularly during food distributions\nOn March 11, 2020, the WHO declared the corona virus (COVID-19) a global pandemic.\nCOVID-19: How to include marginalized and vulnerable people in risk communication and community engagement\nThe LCRP Business Continuity Plan for COVID-19 reviews ongoing impact on LCRP operations and outlines risks and critical interventions needed to ensure life-saving access to services and protection\nThis briefing note summarizes key mental health and psychosocial support (MHPSS) considerations in relation to the 2019 novel coronavirus (COVID-19) outbreak.", "pred_label": "__label__POS", "pred_score_pos": 0.7364050149917603}
{"content": "Description: File: Organisation: Abstract:\nCentral Asia has emerged as one of the worlds fastest growing regions since the late 1990s and has shown notable development potential. This is significant for a region comprising largely of small landlocked economies with no access to the sea for trade. Among the advantages, of the region are its high- priced commodities (oil, gas, cotton and gold), reasonable infrastructure and human capital as legacies of Soviet rule; and a strategic location between Asia and Europe.\nFurthermore, many Central Asian Republics (CARs) have embarked on market-oriented economic reforms to boost economic performance and private sector competitiveness. Central Asia: Mapping Future Prospects considers the regions economic prospects to 2015. It charts recent economic performance, highlighting the economic revival. It also synthesizes recent forecasts and constructs scenarios for future economic variables against a constant global background. Projections include, among others, gross domestic product (GDP), manufactured exports per head, GDP per capita and poverty. A special theme chapter develops a manufacturing competitiveness index to compare the CARs with other transition economies and explores the impact of economic reform and supply-side factors (e.g. foreign investment and human capital) on industrial performance", "pred_label": "__label__POS", "pred_score_pos": 0.9922177791595459}
{"content": "This assessment report provides an evaluation of the long-term commercial viability of farm enterprise advisors (FEAs) and business development advisors (BDAs). It presents a range of findings that aim to inform future investment and the wider adoption of FEA/BDA services. Accordingly, the report then outlines a series of critical factors intended to maximise the commercial success of FEA/BDA services for agribusinesses, before proposing some key recommendations for future donor-funded programmes.\nFarm Enterprise Advisor assessment report\nFile size: 9.35 MB\nFile type: PDF", "pred_label": "__label__POS", "pred_score_pos": 0.975167989730835}
{"content": "Poison Ivy removal in Wakefield is not a do-it-yourself task. It should be handled by professionals who have the right equipment and protective suits to handle the plant extraction. The usual cost of Wakefield poison ivy removal is around $10 per bag. A trailer full can cost a homeowner between $300 and $400. Vine removal can cost $80 to $100 per hour. Overall, a poison ivy removal can cost between $26 up to $133 depending on the location of your house and the number of plants that have to be removed.\nEstimated final cost for poison ivy removal\nItem Quantity Fair Price Treatment Chemicals Cost 321 Square Feet $13.80 Treatment Chemicals Labor 2 Hours $66.27 Totals - Cost to Maintain Lawns - 321 Square Feet $80.07 Average Cost Per Square Foot $0.27", "pred_label": "__label__POS", "pred_score_pos": 0.8561695218086243}
{"content": "Abstract\nPhotoluminescent (PL) and electroluminescent (EL) efficiencies of poly(p-phenylenevinylene) (PPV) film were found to be significantly increased by sandwiching an energy-transferable poly(2-carboxyphenylene-1,4-diyl) (PCPD) layer. Energy transfer from PCPD to PPV in the prepared PPV/PCPD/PPV trilayer film was detected by photoluminescence excitation (PLE) spectroscopy and time-resolved fluorescence decay profiles, and was attributed to the chemical-interlocking between two polymers in the interracial regions. It resulted in a strong increase of the PL intensity, a ∼250-times increase of the maximum external EL quantum efficiency (up to 1.3% photon/electron), and a ∼500-times increase of the maximum light output for the ITO/PPV/PCPD/PPV/A1 device compared to the neat PPV. The significant increase of EL was also attributed to the higher energy bandgap of inserting PCPD layer that trap the holes and electrons in the interfacial regions, facilitating the formation of excitons in situ and energy transfer.\nAll Science Journal Classification (ASJC) codes Chemistry(all) Materials Chemistry", "pred_label": "__label__POS", "pred_score_pos": 0.9719146490097046}
{"content": "A Concerning Gap in Cybersecurity for Medical Technology\nHealth Populi\nOCTOBER 31, 2018\nNotwithstanding mass adoption of antivirus protection and firewalls among healthcare providers, there remains a security gap for biomedical\ntechnologies, according to a report from Zingbox. This concerning finding was confirmed in recent observations from Gartner, which wrote in a market trends report that, “generally, medical devices are not replaced for at least ten years, with many running old software that has not been updated or patched.”", "pred_label": "__label__POS", "pred_score_pos": 0.9501879215240479}
{"content": "Jon Cuncliffe, the deputy governor for financial stability of the United Kingdom’s central bank, the Bank of England (BoE), has warned that the emergence of a cryptocurrency economy may weaken or eliminate bank credit issuance.\nIn a speech delivered to the London School of Economics on Feb. 28, Cunliffe predicted that the integration of stablecoins on social media platforms could lead to people putting much of their money currently held with banks into stablecoin wallets, warning:\n“In such a world, and depending how and whether stablecoins were backed with other financial assets, the supply of credit to the real economy through the banking system could become weaker or indeed disappear. That would be a change with profound economic consequences.“\nThe British envoy to the European Union defines the Bank of England’s role as ensuring that the U.K.’s money “works safely and reliably.” He said that virtual currencies pose “very important questions” for the U.K. government, regulators, and the Bank of England.\nCincliffe urged regulators and central banks to prepare for the unique challenges associated with the emerging cryptocurrency ecosystem before it becomes “systemically important.”\nThe risks of stablecoins “go beyond” existing payment system\nThe BoE official acknowledged that the current financial system as comprising “the equivalent of 18th-century bank clerks with quill pens altering their banks’ ledgers to debit one account and credit another.”\nStablecoins claim to offer a number of benefits, including “very large reductions in the costs of payments, especially cross border,” and “greater financial inclusion through easier and cheaper access to payment services for the ‘unbanked.’”\nHowever, he asserts that regulators must be prepared for risks associated with stablecoins before they achieve “a systemic footprint.” Cunliffe warns that as a result of Facebook’s size, its proposed stablecoin Libra has the potential to reach…", "pred_label": "__label__POS", "pred_score_pos": 0.6150360107421875}
{"content": "A recent case from the Armed Services Board of Contract Appeals provides us with a reminder of what can happen to a prime contractor when it settles a subcontractor claim and then seeks to pass through the settlement amount to the government. In\nKellogg Brown & Root Services, Inc., (November 19, 2018), the prime contractor (\"KBR\") sought to pass through to the government the cost of settling two subcontractor requests for equitable adjustment. The board held that KBR had failed to demonstrate that the cost of settlement was reasonable and denied KBR's claim in its entirety.\nThe underlying prime contract was for the provision of logistics during the United States' military operation in Iraq. The subcontract out of which the REAs arose involved the transport of prefabricated housing through Iraq. The subcontractor, whom the board described as \"sophisticated,\" was impacted by the limitations on the United States' ability to provide security for the transport convoys due to the many demands placed on the military during the time of contract performance.\nThe first subcontractor REA sought over $30 million and, as the board pointed out, was based on \"rates\" and \"prices\" rather than costs. The board pointed out that the subcontractor did not provide actual costs to support its REA. The board further noted that, although KBR initially sought backup information, it lost interest in that information and focused on what a reasonable rate should be. Furthermore, the board noted that KBR did not verify what equipment was actually added as a consequence of the impact to the subcontractor's performance. KBR ultimately settled the REA for approximately $24 million, deciding that the subcontractor's pricing was \"fair and reasonable.\"\nThe subcontractor subsequently submitted a second REA for approximately $42 million that sought reimbursement for idle truck time. The subcontractor's claim was based on rental rates rather than actual costs. In fact, the subcontractor redacted the actual rates when it provided KBR with the truck leases that supported its REA. Moreover, the subcontractor did not provide KBR with actual days of delay upon which its REA was based. Instead, it provided a model that contained several assumptions which the board found unrealistic and inaccurate\nAfter negotiation, including an ignored request by KBR for actual costs, KBR settled the second REA for approximately $24 million based on price rather than cost. The board pointed out KBR never received any data or records showing the actual costs that the subcontractor had incurred.\nKBR paid the subcontractor the agreed upon amounts and sought to pass the amounts paid to the government with administrative markup. The DCAA audit ultimately disapproved of the two payments, finding KBR had failed to obtain accounting and cost data that would support either of the settlement amounts. The ACO ultimately issued a decision that denied reimbursement of almost all of the settlement amounts, the only exception being the cost of a land lease, which the ACO determined had been adequately supported.\nThe board upheld the denial of payment of the settlement costs, noting that FAR 31.201-2 limits payment to costs that are \"reasonable\" as defined by FAR 31.201-3. The board noted it was KBR's burden to establish cost reasonableness, and reasonableness is based on the circumstances at the time the costs were incurred.\nThe board first found that the government's actions in providing convoy protection were reasonable, notwithstanding the impact incurred by the subcontractor. As such, since the government fulfilled its promise to provided protection, it was not prudent for KBR to have paid its subcontractor additional compensation.\nThe board then held that, even if the government had breached its promise, a prudent person engaged in a competitive business would not make the payments that KBR made to its subcontractor. The board pointed out that the subcontractor's model was flawed, the fact KBR did not require the subcontractor to provide its cost support even though there was no proof that such support was lacking and that the subcontractor was sophisticated and indeed there was evidence that such costing was available. The board rejected KBR's argument that the subcontract was for \"commercial items\" and, as such, justified a departure from the requirement that the pricing be reasonable. Finally, the board rejected KBR's assertion that the claim was akin to a \"jury verdict\" method of calculating damages, noting that there were other means available to determine costs and a \"jury verdict\" method of establishing damages does not relieve the claimant from the burden of proving reasonableness.\nThe result was that the board did not attempt to determine what a reasonable settlement amount should have been. Instead, the board found that KBR had failed to establish a \"reasonable\" cost and denied KBR's claim in its entirety. The teaching points are these: (a) as a prime contractor considering a settlement with your subcontractor, make sure you require the subcontractor to establish and support its equitable adjustment with evidence that will be accepted by the government, and (b) consider whether your contractual language and the statutory framework you are operating under allows you to \"pass through\" the subcontractor's REA as a claim rather than paying the claim and then prosecuting the claim on your own behalf.", "pred_label": "__label__POS", "pred_score_pos": 0.6586079597473145}
{"content": "Date:October 26, 2020 Location:Virtual Event\nWith the TCJA reducing the corporate income tax rate to a flat 21%, a significant number of S corporations will likely be converting to C corporations. These same corporations, however, may find themselves down the road desiring to regain S status. This presentation will explore the potholes and obstacles that may hinder travel on this two-way road, including the built-in-gains tax, LIFO recapture, excessive passive income, unreasonable compensation, personal holding company status, excessive accumulated earnings, and re-election time restrictions.\nFor more information and to register, visit the Oregon Association of Tax Consultants (OATC) website.", "pred_label": "__label__POS", "pred_score_pos": 0.6040629148483276}
{"content": "A landmark emergency waiver granted by the FAA has allowed Verizon to deploy industrial drones to inspect their critical infrastructure during the US wildfires, ensuring first responders have reliable communications for disaster response. The drones are made by a company called Percepto, which are currently operating beyond-line-of-sight for this emergency deployment.\nThe FAA granted Skyward, A Verizon company, a temporary waiver that allows company pilots to fly the Percepto Sparrow drone from their homes to inspect critical communications infrastructure near the Big Hollow wildfire in Washington. The waiver permits operations 24 hours a day, with less than 3 miles of visibility and no pilot or observer on site. This is the first time a Beyond the Visual Line Of Sight waiver has been granted that allows pilots to control the drone from home.\nThe Sparrow drone platform is already able to land in high winds and in snow. Percepto recently incorporated a first-of-its-kind integral parachute into the Sparrow.\n“At a moment when we are facing dangerous consequences of climate change and coping with a global pandemic, maintaining the Verizon Network has never been more important,” said Rima Qureshi, Chief Strategy Officer, Verizon. “Innovations in airborne technology have enhanced our ability to inspect our sites without putting engineers in harm’s way, and provide our first responders with reliable communications. We appreciate the FAA’s swift action in granting the waiver, which allows us to deploy a network-connected drone and provide critical services, safely and effectively.”\nDesperate circumstances require desperate measures. Since September 9, the Big Hollow Fire in Washington has burned tens of thousands of acres and caused mandatory evacuation orders in the area. As the air quality was unsafe for humans, it was vital to ensure communication for first responders without putting staff in harm’s way.\nPercepto, which we’ve followed at ZDNet, is a leading provider of autonomous drone-in-a-box solutions for monitoring and securing critical infrastructure and industrial sites. It specializes in rugged hardware and AI-based software that provides real-time insights for assessing risk in industrial inspection applications. The company claims the most deployed drone-in-a-box solution in the market.\nDuring a season of apparent doom, with multiple natural disasters occurring throughout the United States, the ability to safely inspect sites that support critical communications for first responders has never been more important or necessary. The waiver was granted through the FAA’s expedited Special Governmental Interest process and applies to drone support operations for critical infrastructure that maintain communications for emergency responders.", "pred_label": "__label__POS", "pred_score_pos": 0.868541955947876}
{"content": "Abstract\nAccurate and rapid diagnosis of malaria infections is crucial for implementing species-appropriate treatment and saving lives. Molecular diagnostic tools are the most accurate and sensitive method of detecting Plasmodium, differentiating between Plasmodium species, and detecting subclinical infections. Despite available whole-genome sequence data for Plasmodium falciparum and P. vivax, the majority of PCR-based methods still rely on the 18S rRNA gene targets. Historically, this gene has served as the best target for diagnostic assays. However, it is limited in its ability to detect mixed infections in multiplex assay platforms without the use of nested PCR. New diagnostic targets are needed. Ideal targets will be species specific, highly sensitive, and amenable to both single-step and multiplex PCRs. We have mined the genomes of P. falciparum and P. vivax to identify species-specific, repetitive sequences that serve as new PCR targets for the detection of malaria. We show that these targets (Pvr47 and Pfr364) exist in 14 to 41 copies and are more sensitive than 18S rRNA when utilized in a single-step PCR. Parasites are routinely detected at levels of 1 to 10 parasites/μl. The reaction can be multiplexed to detect both species in a single reaction. We have examined 7 P. falciparum strains and 91 P. falciparum clinical isolates from Tanzania and 10 P. vivax strains and 96 P. vivax clinical isolates from Venezuela, and we have verified a sensitivity and specificity of ∼100% for both targets compared with a nested 18S rRNA approach. We show that bioinformatics approaches can be successfully applied to identify novel diagnostic targets and improve molecular methods for pathogen detection. These novel targets provide a powerful alternative molecular diagnostic method for the detection of P. falciparum and P. vivax in conventional or multiplex PCR platforms.\nASJC Scopus subject areas Microbiology (medical)", "pred_label": "__label__POS", "pred_score_pos": 0.5808517336845398}
{"content": "causation. A associated set of points will involve the extent to which we depend on societal regulation versus individual self-assist in defending genetically prone people. All regulatory applications confront choices between societal regulation and concentrating on high-threat people , but these choices might be heightened by the identification of genetic susceptibilities to specific merchandise or substances. For instance, ought to merchandise be labeled to warn people with particular genotypes to avoid using the product, simply as food regimen sodas are", "pred_label": "__label__POS", "pred_score_pos": 0.5719155073165894}
{"content": "Abstract : Chrysochromulina Ericina Virus CeV-01B was isolated from Norwegian coastal waters in 1998. Its icosahedral particle is 160 nm in diameter and encloses a 474-kb dsDNA genome. This virus, although infecting a microalgae (the haptophycea Haptolina ericina, formerly Chrysochromulina ericina), is phylogenetically related to members of the Mimiviridae family, initially established with the acanthamoeba-infecting Mimivirus and Megavirus as prototypes. This family was latter split into two genera (Mimivirus and Cafetariavirus) following the characterization of a virus infecting the heterotrophic stramenopile Cafeteria roenbergensis (CroV). CeV, as well as two of its close relatives infecting the unicellular photosynthetic eukaryotes Phaeocystis globosa (PgV) and Aureococcus anophagefferens (AaV), are currently unclassified by ICTV. The detailed comparative analysis of the CeV genome presented here confirms the phylogenetic affinity of this emerging group of microalgae-infecting viruses with the Mimiviridae, but argue in favor of their classification inside a distinct clade within the family. Although CeV, PgV, AaV share more common features between them than with the larger Mimiviridae, they also exhibit a large complement of unique genes attesting of their complex evolutionary history. We identified several gene fusion events and cases of convergent evolution involving independent lateral gene acquisitions. Finally, CeV possesses an unusual number of inteins, some of which are closely related despite been inserted in non-homologous genes. This appears to contradict the paradigm of allele-specific inteins and suggests that Mimiviridae might be especially efficient in spreading inteins while enlarging their repertoire of homing genes.", "pred_label": "__label__POS", "pred_score_pos": 0.7315024137496948}
{"content": "This is a simple company friendly consultancy agreement for engaging independent contractors or consultants (e.g. individuals or sole operator companies) to work within a business.\nThis template includes a restraint on the independent contractor to ensure that the independent contractor does not jeopardise the company’s business (by competing or similar) during the term and for a set period after. To be enforceable, a restraint must be reasonable. This, in turn, will depend on the facts relating to the agreement. However, the longer the restraint and the broader the restrained area, the more likely that arguments could be raised about the enforceability of the restraint.\nusing our templates\nUse of a template by business users is free of charge and is subject to you agreeing to our template terms of use.", "pred_label": "__label__POS", "pred_score_pos": 0.9985884428024292}
{"content": "The Target Retirement Date funds (Pathway One) are designed for those participants who wish to base their asset allocation decision on a specific target date, typically aligning the account with the fund that most closely matches their projected retirement date.\nEleven of these funds are included in the new plan, with 5-year incremental targets from 2010 to 2055. The way the Target Retirement Date funds are designed, the further away the target date, the more aggressive the asset allocation, conversely, the closer the date, the greater the emphasis on preservation of capital in the asset allocation.\nTarget-Date funds hold some appeal in that they are simple to explain and administer. While this approach is unique, we believe the asset allocation decisions provided by these funds are crude at best. Target-Date funds attempt to make decisions about asset allocation based solely on a target date. An investor’s tolerance for risk and financial goals are other key factors that should largely play a role in determining investment strategy and asset allocation. Additionally, they leave no room for the fund manager to tactically adjust the strategy based on specific opportunities within the financial markets or in response to prevailing market conditions.\nThe returns realized in these commingled vehicles are diluted by a rigid adherence to mechanical allocation parameters. These parameters may prove to be shortsighted and inappropriate for everyone participating in the pool. The real world changes every day, yet proponents of Target-Date funds expect someone to stick to a single game plan for as much as 40 years, whether interest rates are rising or falling, or whether the economy is in expansion or recession. While Target-Date funds offer a simple one-stop-solution, we continue to advise participants to avoid Target-Date funds and retain the flexibility to proactively adjust their portfolios as needed.\nPlease reference The Problem With Target-Date Funds", "pred_label": "__label__POS", "pred_score_pos": 0.8542673587799072}
{"content": "Much of the work on counterfactuals done in linguistics and philosophy in the past forty years has focused on their truth conditions and entailment patterns, in sharp contrast with the literature on indicative conditionals, which has had to reckon with a cottage industry of probabilistic triviality results (starting with Lewis 1976). This is an unfortunate oversight, since intuitions about the probabilities of counterfactuals provide a window into their meaning and the role they play in thought and talk. Moritz Schulz’s book aims to address this gap.\nIn my review, I discuss the central puzzle animating Schulz’s discussion and his proposed solution. The puzzle stems from a plausible empirical generalization about the probabilities of counterfactuals (Schulz calls this Skyrms’s Constraint; see 78–88).", "pred_label": "__label__POS", "pred_score_pos": 0.9566138386726379}
{"content": "Digestive Support Heartburn, indigestion, constipation, and bloating are all common symptoms of sluggish or compromised digestion.\nDigestion is a cascade of physiological events that start before you even put food in your mouth. That anticipatory “mouthwatering” effect is your digestive system kicking into action.\nDigestive prompting can also come from something today’s diets often lack: bitter flavours. These stimulate the vagus nerve in the mouth which ultimately results in the production of saliva, gastric juices, enzymes, and bile — crucial elements of healthy digestion.\nBitters also help the nervous system to shift into “rest and digest” mode (rather than “fight or flight”), which allows for optimal digestion.\nImproving the digestion in this way can also promote greater absorption of critical nutrients, support for the immune system, and a reduction in sugar cravings.\nSt. Francis Herb Farm has uniquely crafted Canadian Bitters: our leading solution for digestive issues. A natural remedy that not only helps resolve those uncomfortable symptoms but also helps retrain the body’s digestive system, encouraging it to function more efficiently instead of merely providing a temporary solution.", "pred_label": "__label__POS", "pred_score_pos": 0.702509880065918}
{"content": "Cyber Security\nCybersecurity has emerged as one of the most important fields that exists to protect us from digital attacks across all sectors of business, government and in our personal lives…Gov. Doug Ducey.\nArizona is a growing epicenter for cyber solutions in the private and public sectors. This includes military research at places like Fort Huachuca, cybersecurity operations at dozens of American companies, as well as coalitions like the Arizona Cyber Threat Response Alliance, which serves as a hub for cyber information-sharing with partners from industry, academia, law enforcement and intelligence.\nA 2015 report, “Job Market Intelligence: Cybersecurity Jobs, 2015,” ranked Arizona # 15 in the country for total job postings in the sector. Phoenix-area job postings increased 101 percent between 2010-14, compared to 91percent nationally.", "pred_label": "__label__POS", "pred_score_pos": 0.508021891117096}
{"content": "Noting the augmenting of fake invoice registration, the Centre and States have jointly decided to further tighten the process of GST Registration as well as the legal process surrounding it.\nA meeting of the Law Council of GST has been summoned to deliberate on the matter and chart out paths that can be adopted to achieve this conflated goal. The committee is expected to discuss fake invoice frauds, a greater tightening of the GST registration process and iron out further legal measures including any necessary law amendment required in the GST Act to put a significant check on fake invoicing.\nIt is expected that provisions relating to the deemed registration under the GST Law will face scrutiny and may be tightened along with the streamlining of provisions related to suspension under the existing law. This would come as a pre-emptive move to expedite the process of suspension and make it significantly less complex so that it becomes easier to identify, process and punish fraudulent accounts while removing them from the system.\n“It is also learnt that data analytics techniques will be used to identify such taxpayers, who are suspected to be indulging in fraudulent activities and a coordinated action is likely to be taken against such elements by suspending their registration, followed by detailed physical and financial verification by field officers to check genuineness of their operations, before they are allowed to reuse their registration,” A Financial Express source notes\nThese moves come in the aftermath the booking of more than 393 cases by The Directorate General of GST Intelligence (DGGI), the investigation unit under GST. It has identified approximately 1,282 entities and arrested more than 30 odd people as a result.\nIt is expected that businesses, whose owners not having a good financial track record, like filing of income tax returns and payment of income tax to the government, may require detailed physical and financial verification by tax officers, before their companies can be considered for GST registration under the new set of changes which will be released by the government soon.", "pred_label": "__label__POS", "pred_score_pos": 0.714152991771698}
{"content": "Associate feature: supporting vital workers\nSince the beginning of the COVID-19 crisis, across the country people have gained fresh perspectives on the vital work undertaken by the nation’s key workers. Much of this has focused, rightly, on the critical roles of those battling the virus on the front lines, such as NHS staff and those working in the care sector. These key workers risk their lives to care for others and deserve to be supported as much as possible.\nScotland’s teachers provide some of that support through their staffing of the support Hub facilities which have been set up, and which the children of key workers (and, also, some vulnerable young people) can attend during the lockdown. This is a vital role, indeed it brings with it Category 1 key worker status, offering care for these young people while their parents perform essential work in places such as hospitals and care homes. It speaks to the dedication of Scotland’s teachers that the numbers volunteering to work in these Hubs far exceeds the number of staff required daily.\nBeyond that, other teachers are doing all that they can to continue to engage children and young people across the country. Remote teaching and learning bring challenges, for all: teachers, students and parents. It is no substitute for the caring communities which are our schools, but it offers a lifeline platform where teachers can continue to support the health, wellbeing and resilience of our children and young people.\nWhile the COVID-19 pandemic continues to place a great strain on the entire country, Scotland’s public sector workers, including teachers, are doing all that they can to see us through the crisis.\nLarry Flanagan, General Secretary of the Educational Institute of Scotland\nThis piece was sponsored by EIS", "pred_label": "__label__POS", "pred_score_pos": 0.978199303150177}
{"content": "All over the world, people are disinfecting, spraying, and wiping down surfaces with an urgent sense of purpose: They want to kill the coronavirus.\nMany of us are cautious about touching things like ATM buttons, door handles, and hand rails. Some of us wear disposable gloves when we go out. Others even wipe down their groceries after bringing them home.\nWhen the pandemic began, these measures seemed like the best way to prevent the spread of COVID-19.", "pred_label": "__label__POS", "pred_score_pos": 0.7078671455383301}
{"content": "Abstract\nThe lack of an effective detection method for lung circulating tumor cells (CTCs) presents a substantial challenge to elucidate the value of CTCs as a diagnostic or prognostic indicator in lung cancer, particularly in nonsmall cell lung cancer (NSCLC). In this study, we prepared a capture surface exploiting strong multivalent binding mediated by poly(amidoamine) (PAMAM) dendrimers to capture CTCs originating from lung cancers. Given that 85% of the tumor cells from NSCLC patients overexpress epidermal growth factor receptor (EGFR), anti-EGFR was chosen as a capture agent. Following in vitro confirmation using the murine lung cancer cell lines (ED-1 and ED1-SC), cyclin E-overexpressing (CEO) transgenic mice were employed as an in vivo lung tumor model to assess specificity and sensitivity of the capture surface. The numbers of CTCs in blood from the CEO transgenic mice were significantly higher than those from the healthy controls (on average 75.3 ± 14.9 vs 4.4 ± 1.2 CTCs/100 μL of blood, p < 0.005), indicating the high sensitivity and specificity of our surface. Furthermore, we found that the capture surface also offers a simple, effective method for monitoring treatment responses, as observed by the significant decrease in the CTC numbers from the CEO mice upon a treatment using a novel anti-miR-31 locked nucleic acid (LNA), compared to a vehicle treatment and a control-LNA treatment (p < 0.05). This in vivo evaluation study confirms that our capture surface is highly efficient in detecting in vivo CTCs and thus has translational potential as a diagnostic and prognostic tool for lung cancer.\nAll Science Journal Classification (ASJC) codes Analytical Chemistry", "pred_label": "__label__POS", "pred_score_pos": 0.9091343283653259}
{"content": "A\nassociation learning collaborative is a planned program for engaging people from multiple organizations in learning and action to accomplish their goals. CHS supports each step in the process, including design, development, delivery, and evaluation.\nTopics. The learning topics for a collaborative can be focused on any aspects of organizational strategy or community strategy.\nParticipants. Participants may include individuals or teams from member organizations. There are no hard and fast limits on the number of participants., and the mix of participants can be decided based on the topical focus and learning objectives.\nDuration. A collaborative can run from a few weeks to months, depending on the scope and nature of the project.\nStructure. A collaborative typically includes a series of virtual or in-person group learning sessions, coaching and consultation between learning sessions, and an online resource center where participants can access a wide range of content (data, tools, practice guides, etc.). Subject matter expertise is provided by strategically chosen instructors, with CHS consultants facilitating coaching, consultation, and access to online resources.\nPeer Learning. In addition to learning from expert instructors and consultants, participating members learn from each other as they share breakthroughs, challenges, and lessons learned. The opportunity for peer learning is a key part of the value proposition for a collaborative.\nReal-World Impact. Most importantly, participants engage in applied learning by using what they learn in the collaborative to solve real-world challenges in their organization or community,", "pred_label": "__label__POS", "pred_score_pos": 0.9990820288658142}
{"content": "This year marketers are paying a record $4 million for a :30 second Super Bowl ad to reach a record of over 111.3 million viewers. Yet, for that money it’s not enough, advertisers need their ads to go viral. Knowing what makes a Super Bowl ad buzz worthy is important in this high stakes marketing event. There are a lot of predictions and theories out there, but research my colleague and I conducted found that the underbelly of a great commercial is whether it tells a story or not.\nWhat does William Shakespeare have to do with Super Bowl Commercials? Our two-year analysis of 108 Super Bowl commercials found a significant relationship between dramatic form and favorability in consumer Super Bowl ad rating polls such as USA Today’s Ad Meter and Spotbowl.com. The research pulls from Aristotle’s Poetics and “Freytag’s Pyramid” five act plot structure popularized by dramatist such as Shakespeare to reveal the power of story.\nAccording to Freytag, a drama is divided into five parts called acts, and these acts combine to form a dramatic arc: Inciting Moment, Rising Action, Climax, Falling Action, and Moment of Release. We found that consumer ratings were significantly higher for commercials that follow a full five-act dramatic form compared to commercials that did not. Additionally, the more acts commercials had (3 versus 2) the higher the ratings.\nBased on this analysis and advancement of narrative theory, my prediction for this year’s Super Bowl ad winner will be Budweiser’s Puppy Love. Viewers favor ads with dramatic plot lines. Plot is what Aristotle emphasized in Poetics as early as 335 BC.\nThe power of story has already drawn 30 million views on YouTube and significant press coverage for “Budweiser Super Bowl XLVIII Commercial — ‘Puppy Love'” two days before the actual game and official airing of the spot.\n“What Makes A Super Bowl Ad Super for Word-of-Mouth Buzz?: Five-Act Dramatic Form Impacts Super Bowl Ad Ratings” is being published Fall 2014 in the\nJournal of Marketing Theory and Practice. The more complete a story marketers tell in their commercials the higher it performs in the ratings polls, the more people like it, want to view it, and share it.\nWhat are your predictions for Sunday’s Super Bowl ad winners?\nKeith Quesenberry", "pred_label": "__label__POS", "pred_score_pos": 0.6161375641822815}
{"content": "Distributed processes are reliant on replicating data. This creates multiple versions of the truth. That doesn't integrate processes.\nThe use of email, data hubs and warehouse block business agility. These \"solutions\" rely on copying data from one place to another. This doesn't integrate business processes. Email creates insecure costly replicative data management. Your \"solutions\" that centralise data rely on an \"extract\" processes. This increases overheads and blocks business agility.\nA secure data sharing layer embraces your database silos. This allows you to integrate, join-up and extend data across your distributed business processes.\nA proven distributed application to integrate processes.\nOur solution grew from the needs within a small business ecosystem. Their distributed businesses collaborated on data to complete tasks. Prior to our solution decisions were made on gut feelings or using data that was untrusted, duplicated and/or insecure. Within the ecosystem they were duplicating effort and costs to support. This is because they had replicative processes to manage and engage information.\nOur solution provided a way for each organisation to manage their own data. It removes the replication of information across systems. This enabled the organisations greater agility and governance. This reduced their costs as they weren't managing or storing unneeded information.\nThis allowed the business ecosystem to build trust. That is because they shared a trusted layer of data. This allows them to create a foundation. That foundation integrated distributed business processes.\nThe solution we provide empowers organisation to create a distributed, trusted, collaborative, engaging and reuse-able ecosystem of information. This allows them to become proactive to change and mitigate risk. With our solution organisations have a lower total cost of ownership across the ecosystem. It creates value faster and removes duplicated effort.\nOur solution enables organisations to connect information across distributed systems, allowing them to aggregate information into a single view. This remove wastage, disturbance and loss of trust.\nG8CC an application to integrate distributed business processes.\nWith G8CC deliver you have a simple secure data sharing and access layer.\nG8CC provides a simple, low risk solution for:\nIntegrated supply chain. Integrated healthcare data management. Collaborative networks. Police and Public Sector Institutions. B2B data integration. and many more.\nG8CC allows organisation to restrict and remove access to information at any point. This is because organisations don't lose control of their information, this provides greater governance and security.\nG8CC provides the ability to create automated work-flows around unique information. As organisations don't lose control or replicate information, they can make better decision on more and higher quality information. This process makes it simple for organisations to visualise and learn from information.\nG8CC creates an audit-able trial of information around unique inputs. This allows employee's and things to make more informed decisions. This solution also provides a point of contact for previous value, removing risk and loss of knowledge.\nIt provides a simple, yet extremely powerful tool-kit to support the distribution of information within current and future processes. It's simple, low risk and low cost delivery, empowers organisation to focus on current and future needs.\nG8CC's simple tool-kit provides a:\nMiddleware platform that embraces database silos. It provides a low-code interface that supports continuous database integration. This lowers delivery and ongoing costs. Distributed data sharing layer. This manages views, access to data and relationships between information. This allows you to easily extend and build on existing investments. That unlocks business agility, creating resilience.\nG8CC provides a simple application to integrate distributed business processes.\nContact us here to find out how your organisation can benefit from creating a trusted ecosystem of information.", "pred_label": "__label__POS", "pred_score_pos": 0.9276961088180542}
{"content": "Coeur Mining is soaring\nAmong precious metals and mining stocks, Coeur Mining (CDE) is one of the most successful. Its stock has returned more than 500% since the start of the year. The uptrend has been driven by gains in gold and silver prices.\nCoeur’s peers have also gained handsomely since the start of the year, but Coeur has outperformed them.\nCoeur’s outperformance\nCoeur Mining is highly leveraged operationally compared to its closest peers. It’s a high-cost operator, and its operational leverage is the major reason for its outperformance. Following months of precious metal price gains, the company’s fundamentals have started to improve.\nCoeur’s latest quarterly results were strong evidence of this. Its 2Q16 results were a strong beat on consensus expectations. Its adjusted EPS (earnings per share) of $0.11 was higher than Market expectations of $0.02. The beat was mainly led by cost improvements at Coeur’s mines, particularly Wharf and Palmarejo.\nImproving fundamentals along with higher relative leverage are the reasons Coeur is outperforming its peers. As the above graph shows, Coeur has risen 543% year-to-date as of August 9, 2016. Pan American Silver (PAAS) has risen 191%, Hecla Mining (HL) has risen 270%, and Silver Standard Resources (SSRI) has risen 164%. The prices of silver (SLV) and gold (GLD) have risen by 43% and 24%, respectively.\nSeries overview\nThe key question is whether Coeur Mining can continue its outperformance based on its improving fundamentals. In this series, we’ll perform a fundamental and technical analysis of the company. We’ll also explore its near-term challenges and opportunities, do a thorough analysis of costs and production growth, and examine what Wall Street thinks about the company.\nLet’s begin with production levels.", "pred_label": "__label__POS", "pred_score_pos": 0.8082467317581177}
{"content": "Falling prices\nCommodity prices have fallen significantly over the years. As a result, several companies’ margins have been squeezed. Players within the agricultural chemical space (IYM) can’t do much about these prices due to the commodity nature in the business. However, these companies can lower their production cost to protect their margins or increase their market share through consolidation to increase the sales volume.\nAn example\nEarlier in this series, we saw that the Potash Fertilizer segment will form the largest portion of the PotashCorp (POT) and Agrium (AGU) merger. The above chart shows that average potash realized prices for PotashCorp for a merger that’s horizontal, vertical, or both would help the companies tackle falling fertilizer prices in the following ways:\nIt would optimize their combined production facilities and achieve greater economies of scale. The cost-per-product ton goes down and the margin spread increases assuming that fertilizer prices remain at the current levels. It would lower the cost by eliminating redundancies including SG&A costs. It would leverage the logistical network which helps lower the transit costs for products.\nThe case is similar for nitrogen as well as phosphate prices. Fertilizer prices have fallen significantly due to falling crop prices denting the farm income. Optimization of farm technology created a safety net for the growing population by increasing the output. However, this also impacted the companies engaged in the sector.\nMore mergers to come\nRecently, Monsanto (MON) and Bayer AG announced a merger, while Dow Chemicals (DOW)-DuPont (DD) and Syngenta (SYT)-ChemChina are pending mergers. It wouldn’t be surprising if we see more mergers announced. Companies within the agribusiness space continue to consolidate. Read Monsanto and Bayer Ink Merger Deal, but It’s Not Over Yet to learn more.", "pred_label": "__label__POS", "pred_score_pos": 0.9108039140701294}
{"content": "Stock market reaction to 4Q17\nDespite a strong performance in 4Q17 and upbeat guidance for 2018, Sprouts Farmers Market (SFM) stock plunged 2.3% after the company’s earnings release on February 22, 2018.\nSFM’s share price fell another 1.6% on the next trading day. The market had probably been looking for a more significant earnings and revenue beat—similar to what SFM achieved in the previous quarter.\nThe value-oriented natural/organic food retailer is now sitting at a YTD (year-to-date) profit of 3%. It soared close to 30% throughout the year. In comparison, grocery players Kroger (KR) and SuperValu (SVU) saw falls of 20% and 34%, respectively, during the year. In 2018, the two companies are again sitting in the red. While Kroger has fallen a marginal 0.1%, SuperValu has fallen more than 35% to date.\nBig-box retailers Target (TGT) and Costco (COST) have done better. The two companies have risen 16% and 2% to date, respectively. Retail mammoth Walmart (WMT) has, however, fallen 6% in the year, in part due to its recent quarterly results, which failed to impress investors.\nValuations\nSprouts Farmers is currently trading at a one-year forward earnings multiple of 20x, close to the lower end of its 52-week PE (price-to-earnings multiple) range of 18x–27x.\nThe company is trading at a premium to supermarkets Kroger and SuperValu, which are valued at 12.8x and 5x, respectively. However, it has a better earnings potential than these two companies. Its EPS (earnings per share) are expected to rise 24% over the next 12 months. In comparison, Kroger’s and SVU’s EPS are expected to rise 11% and 6%, respectively, over the next 12 months.\nThose looking to invest in SFM through ETFs can choose to invest in the SPDR S&P Retail ETF (XRT). SFM has a weight of ~1.2% in XRT.\nRead the next section to learn about Wall Street’s take on SFM after its 4Q17 results.", "pred_label": "__label__POS", "pred_score_pos": 0.8947451114654541}
{"content": "Returns of integrated energy stocks\nIntegrated energy stocks have recovered since January 2, 2019. Let’s review the returns of six global integrated energy companies since then.\nIf we compare integrated energy stocks’ performances since January 2, Suncor Energy (SU) has done the best. The stock has risen more than 10% since January 2.\nBP (BP) follows Suncor with a return of ~4% since January 2. ExxonMobil (XOM), Total (TOT), and Chevron (CVX) have returned less than 3% each in the stated period. Royal Dutch Shell (RDS.A) has fallen marginally.\nAll six integrated energy stocks’ 10-day moving averages have crossed over their 30-day moving averages since January 2. Usually, this suggests short-term technical bullishness.\nThe rise in crude oil’s price has affected integrated energy stocks since January 2. The price of WTI crude oil has risen 15% in the stated period. Higher oil prices point to better upstream earnings for these companies. The recovery in the equity markets has further supported these stocks.\nValuations and dividend yields\nThe current recovery in integrated energy stocks has affected their valuations and dividend yields. While their valuations have risen, their dividend yields have fallen. Given the latest valuations and dividend yields, let’s evaluate which stocks are looking better than others. We’ll also compare these stocks in terms of their estimated earnings growth.\nBP, Total, and Shell have above-average dividend yields. These three stocks also have below-average valuations. However, in terms of growth estimates, BP and Chevron have above-average growth estimates for 2018.\nOverall, BP stock seems well positioned with an above-average dividend yield, a below-average valuation, and an above-average earnings growth estimate for 2018. Suncor has the highest return but a lower dividend yield, a higher valuation, and below-average growth compared to its peers. High-growth stock Chevron has a lower yield and a higher valuation than its peers. We’ll discuss more about these parameters from the next article onward.\nWe’ll begin with the stock with the highest rise year-to-date: Suncor.", "pred_label": "__label__POS", "pred_score_pos": 0.885992705821991}
{"content": "Overview\nTMR’s report on the\nHydrochloric Acid is an all-important tool for stakeholders in their pursuit to discover avenues for innovation, and further undertake strategic planning for the launch of products and services.\nOur research report on the Hydrochloric Acid serves as a valuable guide for stakeholders. The report deep dives into demand drivers, challenges, and opportunities that are likely to influence the Hydrochloric Acid over the forecast period. These indicators help businesses pave way in a crowded business landscape, and tread ahead in the competition with confidence.\nFurther, the report carries out solid groundwork and divulges details ofs share of key segments of the under product, application, and geography.\nTo ascertain indicators, analysts employed proven research tools and techniques for the same. The analysis of indicators helps business carry out the most strategic planning for competitive advantage. These indicators also help businesses gauge investment proposition and scope of expansion in the Hydrochloric Acid over the forecast period.\nThe report analyzes the competitive landscape of the Hydrochloric Acid at length. The section includes detailed insights into key business strategies used by prominent players. Further, the report analyzes impact of growth strategies on the competitive dynamics and valuable insights into share projections of key players in the Hydrochloric Acid over the forecast period.\nIf you are stakeholder in the Hydrochloric Acid, the analysis provided will help you understand growth model. Click to get a free Sample report in PDF (including ToC, Tables and Figures). The report includes an exhaustive list of prominent players in the Hydrochloric Acid are key players operating in the hydrochloric acid market across the globe are Dow Corning, Du Pont, Pioneer America, BASF SE, Lyondell Chemical Company, and Bayer. The research study has provided detailed profiles of these players in order to offer a strong understanding of the market and guide the new players in making effective business decisions in the near future.\nFor further know-how of competitive outlook, the report discusses SWOT analysis of prominent players, and how this will impact the competitive hierarchy until the end of the forecast period. This serves as a crucial intelligence indicator to gauge growth strategies adopted by stakeholders, and their stance on mergers, acquisitions, partnerships, and collaborations that can help remain competitive.\nKey Questions Answered in the Hydrochloric Acid Industry Report How much revenue the Hydrochloric Acid is expected to garner over the assessment period between 2016 and 2024? Which product segment is anticipated to lead by the end of the forecast period? Among all, which region is likely to account for leading share in the overall Hydrochloric Acid until the end of the forecast period? What are critical growth strategies employed by prominent players to remain competitive in the Hydrochloric Acid? What are key developments that have come to the fore in the Hydrochloric Acid?", "pred_label": "__label__POS", "pred_score_pos": 0.9478666186332703}
{"content": "In my new book, “Shaping China’s Global Imagination: Branding Nations at the World Expo,” I explore the idea of nation branding—what it is and how it works—through the instructive case of the Shanghai World Expo. Despite the...KEEP READING\nTwo CPD Research Fellows Co-Edit Nation Branding Book\nCPD is pleased to announce that CPD Research Fellows Diana Ingenhoff (2017-2019) and Alexander Buhmann (2016-2018) have co-edited a new volume on nation branding, titled\nBridging Disciplinary Perspectives of Country Image Reputation, Brand, and Identity.\nThe book includes a compilation of chapters on country image, brand, reputation and identity that span multiple scholarly disciplines such as international marketing, public diplomacy, issue management, communication and social psychology.\n\"This volume provides an overview of current scholarship, places related research interests across disciplines in a common context, and illustrates connections among the constructs,\" explains the publisher. \"Discussing how different scholarly perspectives can be applied to answer a broad range of related research questions, this volume aims to contribute to the emergence of a more theoretical, open, and interdisciplinary study of country image, reputation, brand, and identity.\"\nIngenhoff and Buhmann join co-editors Candace White of the University of Tennessee and Spiro Kiousis of the University of Florida in this contribution to the field of public diplomacy.\nMore information about the book is available here.\nTags Visit CPD's Online Library\nExplore CPD's vast online database featuring the latest books, articles, speeches and information on international organizations dedicated to public diplomacy.\nPopular Blogs October 14 November 13 October 30 September 29 November 16", "pred_label": "__label__POS", "pred_score_pos": 0.5969497561454773}
{"content": "According to the Centers for Disease Control and Prevention (CDC), “social distancing” means remaining out of congregate settings, avoiding mass gatherings and maintaining a distance of around 6 feet from others when possible.\nPurpose of Social Distancing\nAs a result of the ongoing COVID-19 (coronavirus) pandemic, social distancing is a concept being encouraged in the hope that it will slow down the spread of the epidemic and decrease pressure on the healthcare system.\nImplementing Social Distancing Measures Reduce the frequency of large gatherings, and limit the number of attendees per gathering (cruises, concerts, conferences, etc.). Close short-term facilities as needed Encourage staff to work from home (when feasible) Avoid dining in restaurants and utilize drive-thru, pickup, or delivery options Avoid discretionary travel, shopping trips, and social visits Individuals at increased risk of severe illness should consider staying at home and avoid situations of potential exposure.", "pred_label": "__label__POS", "pred_score_pos": 0.8695252537727356}
{"content": "Planning, planting and sustaining a new church require an assortment and blending of skills and leadership agility to gain and maintain traction. I propose a connectional leadership model as a comprehensive way to “get” the leadership moves and mindset needed to plant and sustain a new church.\nOne of the most common behavioral types relates to individualized effort and motivation. Within your ministry team, each member offers certain strengths, skills, and intrinsic motivations. Recognizing, affirming, and blending individual assets enables a team to function with greater effectiveness. When you fail to involve people meaningfully, it inevitably leads to low-level ownership and personal investment. Based on my new church observations and experience, I suggest that the individualistic styles of leadership include what I would call intrinsic, performance, and power modes.\nThe intrinsic or self-motivating expression illustrates church leadership from the “inside out”. Some people respond to tasks because they view the objective as challenging and important. When you cast and re-cast a compelling vision, it ignites people to apply imagination and effort toward that vision. The performing-oriented expression reflects an individual’s natural passion for being his or her best in a given function on the team. The power style offers the picture of an individual who prefers operating as a dominant director. If you’re a dominant director, then you readily embrace challenges, gladly assume authority, and thrive on problem-solving.\nI’ll bet you can readily identify servants in the typical new church who are dominantly individualistic in their leadership style – right? How does it help you as a leader by being sensitive to such differences and nuances? Next month, I’ll invite us to explore what I would term the instrumental leadership style as we continuing thinking about the connectional leadership model.", "pred_label": "__label__POS", "pred_score_pos": 0.669032096862793}
{"content": "Programmes on payments for environmental services aim to provide economic incentives for the conservation of natural resources. They are expected to generate a continuous flow of environmental services in the long run, along with maintaining their quality. This essay elucidates the conditions required for the successful implementation of PES schemes and considers how well they may do in the Indian context. It foresees a number of formidable challenges in the schemes producing the desired outcomes in India.", "pred_label": "__label__POS", "pred_score_pos": 0.9982675313949585}
{"content": "A conference, which is expected to offer insights into international business growth opportunities and potential collaborative opportunities between Asean members, was launched in Thailand today, August 3.\nThe five-day “Executive Programme on New Economy 2019″ conference will focus on hearing from experienced practitioners and industry experts to build actionable capabilities and new networks to drive business growth and international branding in the new economy.\nSpeaking at the opening ceremony, Prinn Panitchpakdi, a member of the board of directors at New Economy Academy, said the conference was aimed at strengthening cooperation among Asean countries, including Cambodia, Laos, Myanmar, Vietnam and Thailand.\nThe conference is also expected to allow participants to share experiences on economic growth in the digital era, he said.\nAccording to the organising board, with a high digital literacy, a young population, and an emerging middle class, Asean is set to reap the full benefits of cross-border trade in the digital economy. Speakers also underscored the need for enterprises to seek out appropriate ecosystems, including payment, financial management and logistics, to best match the needs of the market.\nThe board also suggested that governments shift their roles from being regulators to facilitators, who will foster conducive cross-border digital trade ecosystems.\nWith this in mind, participants will receive opportunities to explore further on these topics and engage with Asean thought leaders in multiple dimensions, including international expansion, cross-border e-commerce and digital trade ecosystems.", "pred_label": "__label__POS", "pred_score_pos": 0.9662072658538818}
{"content": "Teaching methods\nOur education focuses on Development Studies and offers a strong multidisciplinary and interdisciplinary field of study seeking to understand social, political and economic change and development\nCritical thinking\nOur students are encouraged to develop a critical understanding of major debates, theories and strategic interventions and of the skills to analyze the issues, and to design and assess interventions aimed at tackling these issues.\nAn essential part of this process is to develop skills in research methodology, which will be applied in a research paper prepared as a requirement for the Masters degree.\nEngagement and Impact\nWe offer top-notch education with a wide variety of courses, teaching not only theory and content but also situating that knowledge in different social, economic and cultural contexts. Students learn to respond to our world’s needs by being critical and constructive, analyzing development, and translating insights into plans and concrete action.", "pred_label": "__label__POS", "pred_score_pos": 0.6815381050109863}
{"content": "The Federal Railroad Administration (FRA) submitted to the Federal Register a final rule allowing railroads to use ultrasonic inspection technology, augmented with global positioning system (GPS) technology, to employ continuous rail testing. These updated regulations are expected to improve safety by making it easier for railroads to test rail more frequently and to identify and repair internal rail flaws before conditions degrade safety.\nThe regulatory reform allows rail testing vehicles to move without stopping along the track, potentially decreasing passenger and freight train delays associated with routine inspections.\nFast-developing technologies challenge regulators to craft and revise regulations that help ensure public safety, while allowing railroads to test and implement innovative inspection methods.\nFRA has issued waivers for the past 10 years, allowing larger railroads to develop and utilize this technology, and the updated standards are consistent with the state of the practice.\nBetween May 2019 and May 2020, there has been a 27% reduction in broken rail-caused train accidents, which is largely attributable to this new technology. Providing all railroads the option of using this technology presents an opportunity to improve the industry’s overall safety record.\nThe Final Rule on Rail Integrity Amendments & Track Safety Standards focuses more on providing performance-based outcomes, rather than prescribing exactly how companies conduct effective tests. Railroads will be expected to utilize established methods to conduct required rail inspections, but they will also have the flexibility to utilize new technologies and methods as they are proven safe and effective.\nContinuous rail testing involves railcars outfitted with ultrasonic and GPS technologies to internally examine rail without stopping. These cars travel along track, collecting detailed imaging and location data. Companies then transmit the information to test monitoring sites where analysts scrutinize the data to identify suspected internal rail defects. Depending on the severity of the potential defect, carriers have between 36 and 84 hours to dispatch teams to the site to inspect the rail. If a suspected defect is verified, FRA regulations require the railroad immediately apply the proper remedial action. In some cases, this means repairing or replacing the defective rail, slowing trains over the defect, or removing the track from service to stop trains until repairs can be made.\nCurrent regulations require ultrasonic rail test vehicles to repeatedly stop and manually inspect to verify indication of defects within four hours. This frequent starting and stopping can require trains operating in the vicinity to travel at slower speeds, often delaying passenger and freight traffic.\nUsing existing methods, companies are typically able to test about 20 miles of track a day. By contrast, companies employing continuous rail testing are typically able to test 80 to 160 miles of track daily.\nFRA estimates that one continuous railcar could replace three to five stop-and-verify test cars. This equates to fewer test cars stopping on tracks, reducing the number of trains that slow to accommodate them. Fewer trains slowing decreases the likelihood of crews exceeding maximum allowable work hours, thus decreasing the expense of unscheduled replacement crews. Ultimately, FRA estimates continuous rail testing could, in 10 years, save the industry $121.9 million.\nMore frequent data collection will produce new data troves, facilitating more detailed research into how track defects develop and propagate over time and how those issues can be addressed before adversely affecting rail safety.", "pred_label": "__label__POS", "pred_score_pos": 0.8567352294921875}
{"content": "The normalization agreement between Israel and the United Arab Emirates is a dramatic, historic and strategic accomplishment.\nThe Gulf state is an expert in various fields, and both nations are expected to benefit greatly from these new ties.\nAbu Dhabi, the leader of the UAE, has impressive military capabilities based on a strong army and air force that have already proven themselves in operations beyond their borders.\nThe Emirates already possess advanced American-made defense systems and jet fighters which they successfully deploy in a large operational radius.\nIsrael and the Arab states, including the UAE, have a shared view of Iran as a strategic and even existential enemy.\nOn the one hand, Iran benefits greatly from its economic ties to the UAE, but on the other it is no secret that if Tehran could it would have conquered the Gulf states if it were not fearful of the consequences.\nIsrael, as a key pillar of its national security policy, must invest great effort and resources in deepening its security and diplomatic ties with the Arab nations.\nIts success in this endeavor is noteworthy and improves its abilities to handle the Iranian threat.\nIsrael enjoys its unprecedented security stability due to the IDF and its overall image.\nThe Arab nations, which tried time and time again to annihilate Israel militarily, have reached the conclusion that it is better to cooperate with it, chiefly in the matters of state and military security.\nBut Israel must not forget that this stability could vanish at any point. The connection Jerusalem has with Washington is crucial in this regard. The U.S. has pledged and continues to commit to maintaining the IDF's military advantage, a commitment enshrined in U.S. law.\nIn practice, the United States refrains, as its policy is required by law, from selling advanced and sophisticated weapons systems to Arab countries, even those among them that are associated with Israel in peace relations.\nAn example of this commitment is the F-35 fighter jets the IAF acquired over the past years.\nThese planes are essentially a multi-level and sophisticated defense system that grant Israel total military supremacy in the region.\nIn the world of intelligence, there are two thresholds: the intentions of the other side and its capabilities.\nIntentions are fluid and prone to rapid change, and while the ability to threaten is built through a slow process, it can become a serious problem if and when those intentions do change.\nTake Turkey, which was once a close friend of Israel but has now become a strategic foe.\nThe same goes for Iran, which before the 1979 Revolution was a soulmate with deep ties to Jerusalem, but is today its number one enemy.\nIn the 2011 Arab Spring, the Muslim Brotherhood took over Egypt and nearly created a dual threat with Turkey against Israel. Fortunately, Egyptian President Abdel Fattah el-Sisi has saved Israel from this menace.\nIn various conversations with my respected Arab colleagues, I was asked why Israel would not allow the Arab nations to be on the same military footing and refuses to abandon its desire for qualitative advantage.\nMy answer was very simple: As long as Israel maintains this qualitative advantage, stability and peace will endure.\nUnfortunately, this is the essence of the Middle East.\nThe only way to maintain peace and long-term stability in the region is for Israel to prevent the sale of American-made F-35 fighter jets to any other Middle Eastern state, regardless of current or future relations.", "pred_label": "__label__POS", "pred_score_pos": 0.7038286924362183}
{"content": "Unions Unions\n14 April 2020\nLondon’s ambulance service has been under heavy strain. But it has not buckled. Key to its resilience has been the acceptance of responsibility by the main trade union, Unison.\n30 March 2020\nUnions are rapidly reaching agreements to protect workers and maintain vital services in the face of the coronavirus epidemic.\n10 January 2020\nThe Labour Party is a walking corpse. And unless the established trade unions change tack, they will follow it to irrelevance. The time is ripe for de-coupling trade unions from the Labour Party.\n1 September 2019\nA pro-Brexit RMT activist has been “no-platformed” by two prominent journalists, who are among the darlings of so-called \"left\" EU supporters.\n13 September 2018\nInstead of calling for – effectively – a second referendum, TUC unions should follow the RMT’s lead and assert their own sovereignty against the employers.\n3 July 2018\nDespite a recent annual congress with no motion on a second Brexit referendum, academics’ union leader Sally Hunt has started a consultation on the question.\n18 January 2018\nUnder orders from the European Commission, the European Central Bank and the IMF, the Greek government has pushed through the most anti-union law in Europe.\n16 October 2017\nWorkers need trade unions as much as ever. The TUC and its affiliates are now preparing for the momentous 150th anniversary in 2018. What can we learn from the TUC’s history?\n12 September 2017\nThe RMT union continues to challenge the TUC’s favourable and unrealistic view of the EU. The TUC believes that the single market is good for British workers and that the UK can remain in it after Brexit. Neither is true.\n24 August 2017\nWorkers at two McDonald’s outlet are to go on strike on 4 September in a dispute that centres around union recognition, cuts to hours and bullying linked to union membership.\n7 July 2017\nFirst they will, then they won’t. TUC indecision over its “Britain needs a pay rise” campaign is fast becoming a tradition.\n7 July 2017\nThe Tolpuddle Martyrs were transported for resisting starvation wages and forming a trade union. The annual festival commemorating them starts on Friday 14 July in Tolpuddle, Dorset.\n25 February 2017\nSince the birth of industrial capitalism, a web of industrial sinews has held the constituent regions of Britain together. The recent dismembering of much of that web has brought not only economic collapse to regions but also threatened our national integrity. We recount struggles in Scotland, London and North Wales that pursued essential class goals of improving wages and conditions of work.", "pred_label": "__label__POS", "pred_score_pos": 0.647405743598938}
{"content": "GST impact Transport and logistics (T&L) sector What to expect\nThe registration, payment and refund processes under GST will be routed through a centralised common portal set up by GSTN. The common portal will act as an interface between the taxpayers, authorities, banks, RBI and accounting authorities. At the back-end, the portal will be integrated with the IT systems of the central and state governments. The GSTN will be linked to the government databases to verify the data submitted on the GST portal by the taxpayer at the time of registration or filing of returns.\nOpportunities for T&L sector\nIn the medium-to-long term, GST will be a key enabler for businesses to rejig their supply chain, in accordance with various business considerations. Consolidation of warehouses GST presents an opportunity for industry players to consolidate their warehouses and set up larger facilities, which will bring in supply chain efficiencies.\nImproved efficiencies due to reduction of trade barriers One of the factors leading to the downtime of vehicles is trade barriers, such as check-post inspection, filing of waybills /entry permits, compliances under Entry Tax laws and local levies. Under the GST regime, the interstate movement of goods will be subject to IGST, wherein all movements will be ‘tax paid’. Additionally, the GSTN will have an audit trail of the movement of goods across the state boundaries.\nGST will lead to optimisation of delivery schedules and the operational costs of transporters, resulting in competitive pricing.\nRe-evaluation of sourcing and manufacturing decisions\nAmong other factors, sourcing and manufacturing decisions are presently dependent on indirect tax considerations. In the GST regime, due to fungibility of credits, these decisions shall be made from a supply chain perspective.\nE-commerce Under the present indirect tax regime, the e-commerce industry is facing significant challenges. Disputes exist with respect to payment of VAT in the destination states. Some of the states have also levied entry tax on e-commerce goods. Further, the industry has also faced significant bottlenecks due to scrutiny at check posts.\nUnder the GST regime, it is expected that clear guidelines on the taxability of e-commerce transactions will be issued, providing much-needed relief to the e-commerce industry.\nFree Trade Warehousing Zones (FTWZ)\nIf the GST law extends benefits of tax-free supply to an FTWZ unit for onward exports, the FTWZ units will be able to attract significant volumes.\nSupply chain considerations under the GST regime Supply chain design will be based on demand management and logistical benefits rather than tax costs Proactive efforts will create a ‘first-mover’ advantage in the T&L sector. The industry needs to evaluate the following steps from a supply chain perspective: A snapshot of GST compliances Assumptions: It is assumed that the services depicted above are business to business (B2B) services. Furthermore, the broad taxability has been determined on the assumption that the service provider has obtained registration in each state where the services are deemed to be supplied. The tax implications have been determined on the assumption that the place of supply for the T&L sector will be the location of the service recipient. Request a consulation at contact form", "pred_label": "__label__POS", "pred_score_pos": 0.5190231800079346}
{"content": "Radicava (edaravone), an approved treatment for amyotrophic lateral sclerosis (ALS), can be taken for up to one year without losing its effectiveness, and benefits patients who delay its start — say, after six months of placebo in a clinical trial, a post hoc analysis of that Phase 3 study suggests.\nThese findings were in “Long‐term edaravone efficacy in amyotrophic lateral sclerosis: Post‐hoc analyses of Study 19 (MCI186‐19),” a study published in the journal\nMuscle Nerve.\nRadicava, developed by Mitsubishi Tanabe Pharma America (MTPA), is a free radical scavenger designed to reduce oxidative stress — an imbalance between the production of potentially harmful free radicals and a cell’s antioxidant defenses — which is thought to be one of the causes of nerve cell death in ALS.\nThe treatment was approved in the U.S. in 2017 based on findings from Study 19 (NCT01492686), a double-blind Phase 3 clinical trial in Japan that assessed the safety and efficacy of Radicava in people with ALS.\nIts 137 participants were randomly given either Radicava or a placebo, both via intravenous (IV, into-the-vein) infusions, for 24 weeks. Results showed that those on Radicava experienced a significantly slower decline (by 33%) in their ability to perform everyday activities, compared to those on placebo.\nPhysical abilities were assessed using the ALS functional rating scale-revised (ALSFRS-R), which measures the ability to perform such daily functions such as speech, swallowing, and dressing. Patients on placebo lost an average of 7.5 ALSFRS-R points over six months, while those on Radicava lost 5 points during the same period, a difference in decline of 2.5 ALSFRS-R points.\nAfter six months, patients had the opportunity to enter an open-label extension part of the study, where all would be treated with Radicava for an additional 24 weeks (about six more months) to explore its long-term safety and efficacy.\nIn total, 123 patients enrolled here, 65 previously on Radicava and 58 from the placebo group. Extension study findings suggested that those staying with Radicava continued to experience slower disease progression, while those previously on placebo started to benefit from the treatment.\nThe lack of a placebo group throughout the entire study’s 48 weeks — serving as a comparative control group — limited the conclusions that could be drawn. This led researchers at MTPA to conduct a post hoc analysis, meaning an analysis done after a study has finished, to better understand Radicava’s long-term efficacy in ALS.\nUsing data from the double-blind first part of Study 19, and assuming that ALSFRS-R declined in a linear manner over time, researchers estimated likely progression in patients on placebo and on Radicava for the first 24 weeks. They then used that estimate to predict progression within each group — with no change in treatment status — over the next six months.\nFinally, they compared this projected progression with the actual rate of progression among patients using Radicava for the entire 48 weeks, and for those who switched to Radicava from placebo for weeks 24 to 48.\nThe analysis helped them to compare projected disease progression without Radicava for 48 weeks with actual progression with Radicava’s use for 48 weeks (about 1 year), and against actual progression in those with six months of placebo followed by 24 weeks of Radicava.\nHad patients remained on placebo for 48 weeks, their projected decline would reach 13 ALSFRS-R points, the analysis showed. This decline was significantly greater than the actual decline seen in Radicava-treated patients for 48 weeks, who experienced an 8-point reduction. (The analysis’ projected decline over about one year of Radicava’s use was 8.6 points.)\nThis point gap amounted to a 38% difference in disease progression among those treated continuously with Radicava, and those who would have remained on placebo for 48 weeks (the projected group).\nThe projected decline in a 48-week placebo group was also greater than the actual decline experienced by those who switched to Radicava for a final 24 weeks. Their ALSFRS-R scores were 10.9 points lower than at the study’s start.\nThe rate of progression was also similar between the continuous Radicava and placebo-Radicava switch groups, “supporting treatment benefit of edaravone in ALS patients who begin receiving treatment later in their disease course,” the researchers wrote.\nAmong study limitations noted was the assumption that ALSFRS-R scores decline in a linear manner, which may not be true in early and late disease stages. This should be addressed in future studies of Radicava’s long-term use, the team recommended.\nAnother post-hoc analysis of Study 19 was shared at a Virtual Clinical Trial Session of the recent MDA Conference, in the presentation “Post hoc analysis of edaravone Study 19: efficacy in bulbar onset ALS patients with and without reduced pulmonary function.”\nPatients with bulbar-onset also benefitted from a year of Radicava regardless of their forced vital capacity (FVC, a measure of lung function) being above or below 80% at the start of treatment.\n“ALS patients with bulbar-onset disease receive a significant benefit from initiating edaravone treatment regardless of whether they have baseline FVC ≥80% or <80%,” the researchers wrote.\nWe are sorry that this post was not useful for you!\nLet us improve this post!\nTell us how we can improve this post?", "pred_label": "__label__POS", "pred_score_pos": 0.800851047039032}
{"content": "Grant Administration: Section 5.4 Other Environmental Review Approaches Tiered Reviews\nTiering is a specialized form of conducting environmental reviews and is not appropriate for all activities, funding sources, or grantees. However, using tiered reviews may increase efficiency when at the planning level the RE does not yet fully know the specific timing, location, or environmental impacts. For HUD environmental reviews, tiering may be appropriate when the RE is evaluating a collection of projects that would fund the same or very similar activities repeatedly within a defined local geographic area and timeframe but where the specific sites are not yet known. Some examples include housing rehabilitation or homebuyer projects in a specific community or a redevelopment project with repeated activities such as sidewalk improvements for low- and moderate-income households. In such instances, the RE:\n1. Completes an up-front programmatic completion of the environmental review form, often the Environmental Review for CEST form that identifies potential applicable compliance areas (Attachment 5-3). This is considered the Tier 1 review.\n2. Performs Tier 2 review when specific properties are identified providing the address-specific review criteria. The RE may use the Statutory Checklist to complete the Tier 2 review (see Attachment 5-13). For many housing-related projects, the applicable Statutory Checklist compliance will be limited to historic preservation, floodplain protection, and wetlands protection.\nAttachment 5-13: Statutory Checklist\nUsing this process, grantees can publish a NOI/RROF and receive a Release of Funds based on the programmatic information. The Release of Funds for such situations will be conditional on the grantee completing an individual Statutory Checklist for each specific rehabilitation project. This site specific Statutory Checklist for each individual rehabilitation address must then be completed prior to incurring hard costs for that property.\nRe‐Evaluation of Previously Cleared Projects Sometimes, projects are revised, delayed or otherwise changed such that a re‐evaluation of the environmental review is necessary. RE must re-evaluate environmental findings when: Change in nature or extent of project, New environmental circumstances or conditions occur Selection of alternative not in original finding\nThe purpose of the RE’s re‐evaluation is to determine if the original findings are still valid. If the original findings and FONSI are still valid, but the data and conditions upon which they were based have changed, the responsible entity must amend the original findings and update their ERR by including this re‐evaluation and its determination. CDFA will accept environmental reviews up to 3 years old.\nA sample determination is provided as Attachment 5‐14.\nAttachment 5-14: Re-Evaluation of Environmental Review It must document the following: Reference to the previous environmental review record, Description of both old and new projects’ activities and maps delineating both old and new project areas, Determination if FONSI is still valid, and Signature of the certifying officer and date.\nPlace the written statement in the ERR and send a copy to CDFA with the Request for Release of Funds (RROF).\nIf the responsible entity determines that the original findings are no longer valid, it must prepare an EA or an EIS if the evaluation indicates potentially significant impacts.\nAnother Agency is Involved When another federal or state agency has funds in the project, it will frequently conduct its own environmental review process. The grantee is free to use that agency’s review to compile its own record. In fact, it makes some sense to avoid unnecessary duplication of effort. However, other federal agencies do not always cover all of the same environmental requirements as HUD. The grantee is reminded that: Use of another agency’s documentation does not avoid or minimize its own responsibilities for fulfilling the compliance reviews for CDBG. Conduct of the public comment requirements must still be fulfilled.\nBefore making a finding based on another agency’s review, the RE should check the review carefully against the requirements referenced in this chapter, to ensure that the contents are sufficiently inclusive to allow the grantee to meet its responsibilities. There are HUD-specific review criteria that are not performed by other federal agencies. If that review falls short in certain areas, it can be supplemented by the grantee to meet its requirements.\nRemember, the grantee cannot simply substitute another agency’s hearing and comment process for the notice requirements referenced here. The grantee must check that the public comment process and review requirements fulfil the format prescribed in this implementation guide.\nIf possible, it is encouraged that the grantee combines the comment process for funds from the same federal agency (HOME and CDBG, for example). Please contact CDFA for additional guidance on combining notices with other agencies.", "pred_label": "__label__POS", "pred_score_pos": 0.616934597492218}
{"content": "An exploration of the pedagogies employed to integrate knowledge in work-integrated learningJournal of Cooperative Education & Internships, 43 (1) , 14-35.\nIn a national research project analyzing data from employers, students, and practitioners, the study finds a lack of consistent methods and pedagogies for ensuring integration of knowledge in New Zealand’s Work-Integrated Knowledge (WIL)/cooperative education program. Makes specific recommendations for practitioners based on these findings.", "pred_label": "__label__POS", "pred_score_pos": 0.9931284785270691}
{"content": "PaperSustainability Collaborating for a low-carbon world\nIn this paper, we provide an overview of our engagement approach; expanding on the rationale of our climate engagement program – the reasons why we engage on climate and how we select those companies we are engaging with; the role our engagements play as part of our overall integration of ESG or sustainability issues within the investment process and lastly, provide insights into the learnings and best practice which our engagements have revealed during the period.\nWe see corporate engagement as an intrinsic part of the investment process. It can deepen our knowledge of, and confidence in those companies we invest in, as well as offering a way of building relationships and collaborating with company management. This in turn allows us to monitor, and where necessary, drive corporate conduct on issues that affect the companies’ long-term value. Such issues typically include strategy, capital structure, corporate governance, climate change and human capital.", "pred_label": "__label__POS", "pred_score_pos": 0.9083279967308044}
{"content": "GSA evaluates GSA Schedule offers in accordance with procedures in the FAR and the General Services Administration Acquisition Manual (GSAM). GSA Contracting Officers determine that prices are fair and reasonable, prior to the award of a GSA Schedule contract, by comparing the prices or discounts that a company offers the government with the prices or discounts that the company offers to its own commercial customers. This negotiation objective is commonly known as “most favored customer” pricing. Since GSA has already determined that prices under GSA Schedule contracts are fair and reasonable, ordering offices do not need to make a separate determination of fair and reasonable pricing and, therefore, do not need to obtain cost or pricing information to establish a GSA Schedule BPA.", "pred_label": "__label__POS", "pred_score_pos": 0.8502069711685181}
{"content": "Eczema sufferers, listen up! We've partnered with Aveeno to help you alleviate your symptoms.\nIf you're one of the 35 million Americans who suffer from eczema, you're probably well aware that there's no cure for your chronically dry, itchy skin. Everything from the food you eat to the climate of where you live can affect your hypersensitive condition and make it worse. While the triggers, symptoms, and severity differ from person to person and often require more personalized treatments, there are still effective ways you can help reduce flare-ups and soothe your inflamed skin on a day-to-day basis. Yep, something as simple as changing your shower temperature can help ease your eczema. Keep reading for more tips that will save your skin.", "pred_label": "__label__POS", "pred_score_pos": 0.6361497640609741}
{"content": "Near the end of 2018, He Jiankui was on the world’s stage announcing that he had edited the genome of twin girls, in the hope of making them resistant to HIV. On Tuesday, December 31, 2019, the\nWall Street Journal (WSJ) printed a report that Dr. He and two others have been convicted of “illegally practicing medicine related to carrying out human-embryo gene-editing intended for reproduction.” (online version here).\nA court in Shenzhen concluded that the defendants had acted for “fame and profit,” when they “deliberately violated the relevant national regulations, and crossed the bottom lines of scientific and medical ethics.” For the crime committed, He received the most severe sentence. In addition to the three-year prison sentence, He is banned for life from “working in the field of reproductive life sciences and from applying for related research grants, “ according to the\nWSJ.\nThe Xinhua News Agency also noted that a third genome-edited baby had been born, and that this child, along with the previously born twins, “would be monitored by government health departments.” The\nWSJ did not state for how long the monitoring would continue. Not only were the children experimental subjects as embryos, but they continue to be subjects as well. Further, these genome effects will affect their progeny, potentially into perpetuity. Additionally, the Smithsonian Magazine reports that in the summer of 2019, He met with “investors to discuss a potential commercial genetic modification clinic in Hainan, which aims to become a ‘world-class medical tourism hub’.” One might reasonably call this “a crime against humanity,” even if it does not include genocide of humans already born. (For further reading, see David Luban, “A Theory of Crimes Against Humanity”)\nIn the print edition of the\nWSJ, alongside the article on He is an article about Pastor Wang Yi of the Early Rain Covenant Church. Pastor Wang was sentenced on 30 December to nine years in prison. His crime was “incitement of subversion of state power and illegal business operations” (online article here).\nConsider that a pastor receives a nine-year sentence for an offense against the State; and a scientist, a sentence of three years for a crime against multiple generations, and indeed, humanity. In the year 2020, we could use a check of our understanding of what is important in the life of the world. Would that our vision were 20/20 also.", "pred_label": "__label__POS", "pred_score_pos": 0.5728602409362793}
{"content": "For 165 years, spiritual development has been a fundamental cornerstone at Jackson-Feild (JFBHS). Today, COVID-19 restrictions have necessitated imagination and ingenuity on the part of our Chaplain, the Rev. Dr. Robin Moore, to fulfill the spiritual needs of the children.\nChapel services had to be modified to meet safety procedures by having five different services—one per cottage. The pandemic has created new opportunities such as “The Gathering Place”, a specially designed haven resembling a cozy den. With two fish tanks to foster an environment of mindfulness, residents can relax and gather in small groups to share what is on their minds.\nLife Guidance sessions are provided for residents to meet individually with the Chaplain for spiritual advice and comfort.\nResidents find reassurance through the Chaplain’s prayer wall. Numerous residents have traced their hand print knowing that when she sees it, she will pray for them.\nGuided meditation sessions are provided to assist residents with fears, anxieties, or to celebrate happiness. Yoga sessions, when requested, follow the teaching philosophy and practice in the Hatha yoga tradition. Hatha yoga can offer a full-body practice with a strong emphasis on the full integration of body, mind, and spirit.\nThe Chaplain also coordinates the care of the JFBHS’s three companion dogs with the help of residents. These dogs provide unconditional love for the children who enjoy and appreciated their love and attention.", "pred_label": "__label__POS", "pred_score_pos": 0.7615291476249695}
{"content": "In this simple but powerful guide, Carnine leads the reader through a process of transformation, opening a toolbox of skills and techniques that anyone can use to live more fully in the moment and be more kind to themselves and others. Carnine reassures us that everyone is capable of building a mindfully kind life — and making it stick.\nSaint Badass: Transcendence in Tucker Max Hell) guides readers through developing a practice of “kindfulness,” an intertwining of kindness and mindfulness. Carnine, a lay Buddhist minister and educator, focuses on motivating readers to be kind to themselves and others in small, immediate ways. His core approach is to replace unkind habits, both physical and mental, and both inwardly and outwardly directed, with kind ones. He also discusses developing skills related to change, action, and character. He uses a straightforward, organized teaching style, supported by jargon-free explanations of simple mindfulness and meditation activities and grounded in the idea that change is possible even in the toughest of circumstances.\nCarnine excels at articulate frameworks and memorable terminology, such as the “Renew-and-Serve Cycle” and the “Three-Breath Method,” without falling into cuteness, oversimplification, or jargon. Each chapter is organized into small, digestible sections and includes definitions of concepts, exercises, and anecdotes from his and others’ personal experience. He brings in just enough of his personal history to make his presence palpable without centering himself, and he avoids the denigration of his past failings. The only things detracting from the professional appearance of the text are hand-drawn illustrations.\nThroughout the text, Carnine includes short sections written by prisoners whom he mentors and corresponds with. They share how their lives have been improved by these practices despite their histories of deep abuse and extreme violence, proving the value of kindfulness in any circumstance or context. These stories also put a subtly masculine spin on the material, offering a path for readers stuck in a mindset of toxic masculinity. Carnine’s articulate and easy-to-follow approach, and the deep sincerity that comes through his and others’ personal stories, create a transformative guide for readers seeking to make changes in their lives and relationships.\nTakeaway: This accessible guide to changing one’s life through “kindfulness” is an invaluable road map for readers whose lives have been affected by toxic mindsets. Great for fans of Elisha Goldstein’s The Now Effect, Jamil Zaki’s The War for Kindness. Production grades Cover: B Design and typography: A Illustrations: C Editing: A Marketing copy: B+", "pred_label": "__label__POS", "pred_score_pos": 0.9177427887916565}
{"content": "Through the community consultations for Towards Race Equity in Education Black students, parents, and teachers shared that parents are critical to ensuring race equity in education. However, Black parents shared that they do not always have the knowledge to successfully navigate the public school system. The Engaged Parent series of information sheets was developed to fill this information gap. This session will introduce participants to the issues Black students face in Ontario’s public education system and share these tools and strategies that parents and caregivers can use to support their children in the public education system.", "pred_label": "__label__POS", "pred_score_pos": 0.9998688697814941}
{"content": "Description\nDigestZen is one of doTERRA’s most popular blends due to its ability to aid in digestion, soothe occasional stomach upset, and maintain overall digestive health.* Now this incredibly effective blend is available in a convenient chewable tablet. DigestTab is a calcium carbonate tablet infused with DigestZen Digestive Blend to deliver the benefits of digestion—supportive essential oils as well as the acid—neutralizing benefits of calcium carbonate.*\nUses\nChew one tablet as needed up to six times daily.\nCautions\nKeep out of reach of children. Do not use with other acid reducers. Ask a doctor or pharmacist before use if you are taking a prescription drug.\nPrimary Benefits Specifically designed for individuals with sensitive stomachs. Combines the unique digestive benefits of calcium carbonate along with pure essential oils from plants traditionally known for providing soothing support to the gastrointestinal tract, including Ginger, Peppermint, Caraway, Coriander, and Anise.* A unique and powerful synergistic blend of natural ingredients designed to relieve occasional heartburn and indigestion, while promoting the overall health of the gastrointestinal tract.* Use with or between meals as needed, for relief from occasional stomach upset, indigestion, and heartburn.* Helps relieve occasional sour stomach.* Provides relief from the uncomfortable burning of occasional acid indigestion and helps reduce unwanted belching and bloating.*", "pred_label": "__label__POS", "pred_score_pos": 0.9131324291229248}
{"content": "1. Breath focus. In this simple, powerful technique, you take long, slow, deep breaths (also known as abdominal or belly breathing). As you breathe, you gently disengage your mind from distracting thoughts and sensations. Breath focus can be especially helpful for people with eating disorders to help them focus on their bodies in a more positive way. However, this technique may not be appropriate for those with health problems that make breathing difficult, such as respiratory ailments or heart failure.", "pred_label": "__label__POS", "pred_score_pos": 0.919611930847168}
{"content": "The COVID-19 pandemic has highlighted the risks and challenges that healthcare workers face every day. This includes injuries, infections, violence, and avoidable safety-related incidents. Due to the stressful environment that these workers struggle with, they are more prone to errors which can lead to patient harm. The World Health Organisation’s World Patient Safety Day (WPSD) …", "pred_label": "__label__POS", "pred_score_pos": 1.0000098943710327}
{"content": "Abstract Informations and abstract Keywords: Digital Inequality; Smartphone Pervasiveness; Learning Outcomes; Mediation Analysis.\nSmartphones diffusion has contributed to the closing of the digital divide, allowing adolescents from all economic and social backgrounds to access the internet. However, the pervasiveness of such devices even in the most relevant moments of the day has raised some concerns about the unexpected consequences of their use. There is an extensive literature highlighting the negative association between smartphone overuse and adolescents' school performances, while recent research finds first evidences of a greater diffusion of this phenomenon among low educated families. Therefore, differences in the amount of resources that parents can invest in the limitation and guidance of their children's smartphone usage may possibly be fostering new forms of social inequality. We tested this hypothesis on a dataset of 489 high-school students, linking their social origins with their smartphone usage habits, grade point average and Invalsi standardized test scores. By means of a mediation analysis, we show that smartphone pervasiveness moderately mediates the negative relationship between family educational background and students' learning outcomes, contributing to the divide between high and low performers.", "pred_label": "__label__POS", "pred_score_pos": 0.6770743131637573}
{"content": "By asking you, the business owner, a set of succinct questions, our experienced transition advisors will input your responses, generate a report, interpret the data, and create a high level summary. This will provide insight into just how likely it is that another party or parties might be interested in acquiring your business.\nProviding you this data will help you, through the lens of an objective advisor, determine the viability of your business beyond your ownership, which is a key component to assessing current value. Presuming the data supports a succession plan for the business, you then can focus on the readiness of your business for a future transition.", "pred_label": "__label__POS", "pred_score_pos": 0.9878680109977722}
{"content": "Coinbase is going to become a credit card issuer for crypto.\nSay it ain’t so?\nYep it is. And according to Meltem Demirors, Chief Strategy Officer of CoinShares, this is part of a broader trend of bitcoin going mainstream.\n“Coinbase is effectively the Chase bank of crypto – you can deposit your money, trade / exchange it, lend it, and borrow against it whether with this credit card or future offerings like crypto-collateral backed mortgages. However, become an issuer in a credit card network isn’t necessarily going to be a driver for adoption – but it will be a boon for people who have their assets in crypto, who can now access a wider variety of banking services,” Demirors said.\nToday’s on-ramps and consumer experiences in crypto are complicated, expensive, and primarily built for speculators, traders, and investors. However, verified crypto users doubled in 2018 to 35MM, according to research done by Cambridge University. While this is impressive, we believe that the results would have been far higher if there were lower friction on-ramps for everyday consumers to participate without heavy regulatory burdens, waiting periods, and overwhelming and intimidating user experiences focused on trading. In fact, while only 8% of Americans own cryptocurrency, 25% would like to own some, and 50% would spend it on everyday purchases.\nCoinShares recently invested in Fold, which is part of a wave of companies focused on building on-ramps to support the next wave of bitcoin adoption: mainstream consumers. Fold enables anyone to spend and earn cryptocurrency on things they do every day – hailing a cab, shopping online, ordering a coffee, and more. Fold seamlessly integrates cryptocurrency rails with traditional payment rails, rewarding everyone with up to 20% crypto-back for spending cryptocurrency or USD online or offline with Fold at their favorite retailers.\n“While Coinbase will allow people who have their capital in crypto to use their crypto assets to access credit, it’s only one part of what we believe will ultimately be a large ecosystem of companies serving both crypto holders and crypto enthusiasts in their payments and spending,” Demirors said. “As the number of cryptocurrency holders and those interested in accumulating it continues to grow 2x every year, companies like Coinbase and Fold will take an increasing share of these large market segments. They are developing compelling use cases and incentive mechanisms to onboard mainstream users into cryptocurrency will be their guide for where to earn and spend it.”", "pred_label": "__label__POS", "pred_score_pos": 0.7488231658935547}
{"content": "Leaky gut is associated with a surprising number of health concerns including seasonal allergies, autoimmune disorders such as rheumatoid arthritis, migraines, depression, and Alzheimer’s, among others. Athletes and postmenopausal women are also susceptible to impaired intestinal permeability. All too often when they arrive at our clinics, patients have not been tested for leaky gut or associated food sensitivities that serve as a red flag for the presence of increased intestinal permeability.", "pred_label": "__label__POS", "pred_score_pos": 0.9210675358772278}
{"content": "Although I don’t believe in\nSanta Claus or the Tooth Fairy, as one commenter suggested, I do believe the Rigsby sisters. The scheme is not a fairy tale, as the commenter suggested. Instead, it represents the application of my experience to the evidence.\nContrary to comments made suggesting I find something amiss about the use of technology as a management tool, I wholeheartedly support such efforts and believe they are even more valuable when Six Sigma and similar measurement systems are integrated.\nHowever, “systemic underpayment” of claims becomes even more likely when success is measured in terms of reduction of loss. When fortunes are made by investors swapping paper, there is nothing far fetched at all about the idea of swapping data to reduce loss.\nThe final post on\nthe scheme follows; but, the end of the series is not the last word.\nNowdy", "pred_label": "__label__POS", "pred_score_pos": 0.708554744720459}
{"content": "12 November 2020\n‘One continent, one law’ is a motto that has been connected to the General Data Protection Regulation (GDPR) to emphasize its key role for overcoming the fragmentation of the European Union (EU) data protection landscape. Nevertheless, and despite the Regulation’s direct applicability across all EU Member States, a multitude of national laws already co-exist with its provisions, and a few more are expected. These national laws specify the GDPR rules, operationalize them, and potentially modulate them. They might, in some cases, also appear to contradict the GDPR, be in friction with other national approaches, and/or trigger questions about the exact applicable rules in certain scenarios.\nThe next event will review developments in Germany, while continuing a general discussion on how to apprehend national developments across Member States.\nOrla Lynskey (Associate Professor of Law at London School of Economics, General rapporteur on Data Protection at the FIDE 2020 Congress)\nAndreas Wiebe (Professor at Georg-August-University of Göttingen)\nFor further resources related to this event, please visit the Specifying the GDPR Resources Page.\nTime: 12:30 - 14:00 (Brussels time)\n12:30-12:35 Welcome by Gloria González Fuster\n12:35-13:55 Presentation by Orla Lynskey\n12:55-13:15 Presentation by Andreas Wiebe\n13:15-14:00 discussion and Q&A\nVenue: online. The platform, together with the link to attend the event, will be communicated to the registered participants in due course.\nRegistration: The event is free to attend but registration is required. Should you face any difficulties with the registration form, please send an e-mail to info@brusselsprivacyhub.eu\nNB the event will take place from 12:30 to 14:00, please disregard any typos in the registration form below.\nKeep up to date of our activities and developments. Sign up to our newsletter:\nCopyright © Brussels Privacy Hub", "pred_label": "__label__POS", "pred_score_pos": 0.5600997805595398}
{"content": "The essential nature of digital technologies and data exchange is clear as reliance on them increases. Consumers must be protected, confident and empowered to benefit from the Fourth Industrial Revolution.\nCPRC aims to address power imbalances and build a movement of organisations fostering socially beneficial data and digital practices and policies, informed by evidence.\nOur research puts consumers and the community at the forefront of change. We analyse the policy framework, identify gaps and make evidence-based recommendations for safer, fairer and more inclusive digital markets.", "pred_label": "__label__POS", "pred_score_pos": 0.9862791299819946}
{"content": "Abstract\nIn\nConsent Puzzles: Narrative Ambiguities of Girls’ Sexual Agency in Literature and Film from the 1990s, I examine post-second wave feminist era films, literature, and media representations that depict what I call “consent puzzles,” or ethically and aesthetically ambiguous depictions of girls’ sexual consent. Although sexual consent can be problematic for adults and for boys, a great deal of attention in both psychological studies and popular discourse emphasizes an overarching concern about how sexual consent operates specifically for girls. In particular, girls are often depicted as the gatekeepers who are either “consenting” or “nonconsenting” to others’ desires, as opposed to being portrayed as agents driving their own sexual interactions. Furthermore, even when girls are depicted as “consenting,” their consent is often deemed irrelevant due to their status as “always already” victims. In addition to representations of blatant nonconsensual sex, girls’ consent might be considered invalidated due to their age, or because of their “sexualization” by popular culture, or both. In this study, I investigate particularly puzzling depictions of girls’ sexual consent—such as reiterations of Lolita, or stories of girls’ sexual desire amidst sexual abuse, or the competing media narratives surround the “Long Island Lolita” Amy Fisher—to show how these narratives not only demonstrate the gray area of consent, but also how they validate girls’ subjectivity, desires, and agency. I then look to the character of Stevie from April Sinclair’s novels as a model for how girls might contend with the innumerable layers in between our ideas of coercion and consent and access the ambiguities of sexual agency, sexual preference, gender, and race. Finally, I bring my study into the present through the contemporary discourse about teen sexting, which further highlights the ambiguities of real and imagined girls’ sexual consent, and I advocate for a more nuanced approach to reading girls’ sexual consent and agency, so that we might better protect girls from sexual assault, while affirming girls’ own sexual subjectivity. Recommended Citation\nMeek, Michele, \"Consent Puzzles: Narrative Ambiguities of Girls' Sexual Agency in Literature and Film from the 1990s\" (2016).\nOpen Access Dissertations. Paper 516. https://digitalcommons.uri.edu/oa_diss/516", "pred_label": "__label__POS", "pred_score_pos": 0.6154505014419556}
{"content": "Health economic models are crucial tools to help better inform healthcare decision-making and support adoption of evidence and value-based innovation.\nThe team’s unique approach lies in building health economic models using a scientific process whilst ensuring these can be applied to real-world settings.\nThe latter models are built to assess the impact of a healthcare solution or new care model on the system and can range from cost-benefit analyses, budget impact models, decision-tree analyses, cost-utility analyses to social cost-benefit analyses among others.\nThe team uses a combination of the latest integrated and public datasets and other research reports, and also supports clients to collect relevant datasets using best practice. Furthermore, scenario and sensitivity analyses are performed using Monte-Carlo simulation to interpret results in a multivariate approach and find a wider range of solutions for the clients. Finally, the team ensures models are user-friendly, flexible, intuitive and scientifically robust through review by an independent expert panel.\nCASE STUDY MOUTH CARE MATTERS ROI\nMouth Care Matters (MCM) is a training initiative aimed at improving the oral health of hospitalised patients. Poor oral health can lead to deterioration in general health.\nHospitalisation changes an individual’s routine, causing stress and anxiety due to discomfort, resulting in a lack of motivation to carry out routine oral hygiene habits. In cases where a patient has cognitive or physical limitations, maintaining healthy oral habits often become of greater difficulty, exacerbating oral hygiene.\nKSS AHSN was commissioned to evaluate the impact of the pilot and the project spread across Kent Surrey Sussex but also to indicate the financial outcomes of a national roll-out.\nOur evaluation showed that across Kent, Surrey and Sussex, the Mouth Care Matters programme was estimated to deliver tangible value in the order of £2.66 of benefit within the health care system for every £1 invested in the project.\nA further £17 is identified in social benefits for every £1 invested.\nThe positive financial impact indicated by the national spread scenario was instrumental in securing additional funding from Health Education England to support a national roll-out.\nThe MCM team has now trained over 100 Trusts across the UK and also developed child-centred training and resources to target paediatric oral-health needs.\nImpact: Our analysis provided evidence to enable further commissioning to support the scaling-up of MCM from KSS to nation-wide.", "pred_label": "__label__POS", "pred_score_pos": 0.846842885017395}
{"content": "Abstract\nNeuronal activity regulates a broad range of processes in the hippocampus, including the precise regulation of translation. Disruptions in proper translational control in the nervous system are associated with a variety of disorders that fall in the autistic spectrum. MicroRNA (miRNA) represent a relatively recently discovered player in the regulation of translation in the nervous system. We have conducted an in depth analysis of how neuronal activity regulates miRNA expression in the hippocampus. Using deep sequencing we exhaustively identify all miRNAs, including 15 novel miRNAs, expressed in hippocampus of the adult mouse. We identified 119 miRNAs documented in miRBase but less than half of these miRNA were expressed at a level greater than 0.1% of total miRNA. Expression profiling following induction of neuronal activity by electroconvulsive shock demonstrates that most miRNA show a biphasic pattern of expression: rapid induction of specific mature miRNA expression followed by a decline in expression. These results have important implications into how miRNAs influence activity-dependent translational control.\nASJC Scopus subject areas Biochemistry, Genetics and Molecular Biology(all) Agricultural and Biological Sciences(all) General", "pred_label": "__label__POS", "pred_score_pos": 0.6169706583023071}
{"content": "Housing stability for both renters and homeowners is the single most important contributor to an individual’s overall well-being, from health outcomes to economic stability.\nAnd yet the Latinx community faces significant barriers to acquiring and maintaining housing stability. Even more so during this global pandemic.\nLanguage is one of the most common barriers that many in our community face, particularly immigrants from Latin America. Additionally, a long history of discriminatory policies has created a sense of distrust between the Latinx community and the government, causing many to choose not to participate in government programs.\nDuring these times of COVID-19, many find themselves facing a greater degree of dual hardships: Latinx individuals disproportionately serve in essential worker roles, exposing themselves and their families to COVID-19. This risk puts both their health and their income stability in jeopardy.\nThroughout COVID-19, my staff at Chicanos Por La Causa (CPLC) has continued to work hard to address these issues and connect our community with housing opportunities. CPLC was founded in 1969 to combat discrimination against Mexican-Americans. Today, we continue to use our cultural competency to offer bilingual services, helping monolingual Spanish-speaking clients navigate the system in their native language.\nCPLC is a trusted resource for the Latinx community. It represents our roots, and we continue to be deeply embedded in the communities we serve. As a result, Latinx community members feel comfortable coming to us for help attaining housing stability.\nWe provide the following comprehensive direct services to renters and homeowners to promote housing stability:\nEviction prevention assistance for renters; Mortgage foreclosure prevention assistance for homeowners; Housing counseling services for renters who want to become homeowners, as well as people experiencing homelessness who want to become renters; Access to food boxes; COVID-19 testing; Utility assistance; Workforce development; Childcare services; and Behavioral health services, including support for victims of domestic violence.\nWe recognize at CPLC that federal housing policies continue to perpetuate longstanding discrimination. We are actively advocating for specific policies to create a more equitable playing field.\nIt’s important to acknowledge that fair housing laws have been heavily enforced since the 1960s. However, while these laws strive to create “equal” opportunity, they neglect to take into consideration the needs of individuals facing multiple barriers to housing. These barriers to housing may include low income, domestic violence, previous foster care, and a number of other factors that put individuals at a disadvantage.\nFor these individuals, “equal” opportunity is not enough because they are not starting with the same advantages. Instead, we must focus on creating “equitable” opportunities that take into consideration our different starting places.\nWe are currently advocating for the implementation of source of income laws that increase the availability of rental units for voucher holders, as well as small area fair market rents – rather than the current general Fair Market Rent structure – to create equity. Both of these policies are designed to help individuals move outside of low-income, low-opportunity areas, thus escaping generational poverty that comes through a lack of opportunity.\nThe existing Fair Market Rent structure in particular is somewhat like a modern-day version of the discriminatory practice of redlining, through which individuals living in low-income ZIP codes were denied access to capital. By basing Fair Market Rent on the average rent per county, rather than ZIP code, the current policy pushes people to low-income, low-opportunity areas.\nWhile we remain focused on advocating for these policies, my team at CPLC has also pivoted to providing services safely during this health crisis, which continues to disproportionately affect the Latinx community.\nWe have expanded our phone bank to offer more of our housing services remotely and have shifted our intake process and homebuyer education classes online, minimizing the risk of exposure while expanding access for the community. We have also grown our eviction prevention assistance program in scale to keep people housed during this time of need.\nIt is imperative that we reduce barriers to housing stability – the foundation of health and economic opportunity. The continued wellness of our nation at large is contingent upon the ability of all people to live a dignified life, regardless of race, ethnicity, or ZIP code.\nDavid Adame is president & CEO of Chicanos Por La Causa", "pred_label": "__label__POS", "pred_score_pos": 0.7810202836990356}
{"content": "The recent crime drama\nThe Sinner offers a meditation on how good and evil are defined in the contemporary moment through its focus on murder and its motives. However, within the framework of the crime narrative, the series fails to challenge ideas about non-traditional belief systems, undermining its seemingly progressive nature – especially during its second season. The Sinner is, at its core, a classic detective narrative wherein a mystery is solved; the generic conventions are altered through the focus on the “why” rather than the “who,” but the puzzle still becomes central as is common within the genre. In the first season, we are introduced to Cora Tannetti, who stabs a man to death on the beach in the very first episode. She is caught and signs a confession, but the detective assigned to her case, Harry Ambrose (the detective in season two as well) starts to unpick her story in the hope of understanding “why,” and unravels a complex motive.\nIn season two, the same plot device of a murder being committed and confessed occurs in the first episode – this time, perpetrated by a child. The narrative is complicated by the child’s background, which is suffused with unorthodox beliefs. We learn the child, Julian, has been raised in a “cult” named by the locals after its location: Mosswood. Throughout the series, there are references to an exploration of existence that merges the psychological and the spiritual, along with a grounding in more mainstream forms of religion, primarily Christianity.\nThe crime genre is seen as an “inherently conservative form that repeatedly rehearses a dominant ‘common sense’ ideology of law and order” (p. 6), according to media studies scholar Jonathan Nichols-Pethick. Within it, particular structures are upheld with the crime often being seen as presenting an imbalance to the status quo, restored by the solving of the crime, and the criminal being brought to justice. In some ways,\nThe Sinner presents a subversion of this formula: rather than the person who committed the murder being jailed, both seasons place the blame with others who contributed to the formation of the disturbed psyche of the character, and they are imprisoned instead.\nThis shifting of responsibility follows a trend in other contemporary narratives where we look to understand\nwhy something immoral or “evil” has happened – such as the recent Bates Motel, which sought to explain the psyche of Norman Bates. By digging into the past of the characters who kill, The Sinner seeks to construct an idea of nurture being the culprit rather than something inherently evil within them, as per older notions of criminal behavior.\nThe cult being seen as a nefarious part of Julian’s upbringing follows in a long tradition of presenting cults in a particular way onscreen, as explored by American religious history scholar Lynn S. Neal. In “They’re Freaks! The Cult Stereotype in Fictional Television Shows, 1958-2008,” she examines a selection of depictions spanning fifty years and finds that similar negative presentations occur, demarcating their difference from “conventional” religious forms. Ultimately, this serves to “polic[e] the boundaries of religious legitimacy in American culture” (p. 81). Locating the cult as a site of evil behavior in a show like\nThe Sinner reinforces stereotypical presentations of practices that fall outside the institutional and more traditional forms of belief that tend to be more socially acceptable. What should also be noted is the use of the term “cult” and its pejorative nature (rather than the more neutral and preferred “new religious movement” found in scholarly circles today). The term is used by those who are actively seeking to disrupt or destroy the “cult” of Mosswood, marking it as a negative identifier.\nThe positioning of the cult as negative is furthered by the behaviors and beliefs shown. The cult is seen worshipping a rock, with a desire to return to the “primitive” rituals of our inner selves, which are in this case defined primarily by violence, ultimately situating the cult as degenerative and barbaric. The characters who live within the cult system are either killed or punished in some way, reinforcing what film scholar Thomas Schatz defines as a “pro-social” ideology – the upholding of status quo through a quashing of beliefs or behaviors that challenge it.\nDespite the changing approach to crime and its motives by focusing on the factors that contributed to the murder,\nThe Sinner ultimately serves to highlight the idea that evil is man-made and can be controlled through societal structures. Although following a trend in contemporary crime narratives of presenting the detectives as flawed or troubled in some way, the detective at the heart of this narrative is also a traditional seeker of the truth. He wishes to expose the darkness that has pervaded both the perpetrator and the world in which they live. The Sinner allows us to explore the psychological motives for the act of murder, but it offers no satisfying resolution for the “victim,” only an undermining of the structure that warped their psyche. Since this season posits the murderer as a victim of the “cult” within which he was raised, it aligns with the notion of the cult as villainous.\nThe transcendental element of the cult, manifested in the symbol of the rock, is shown being smashed at the end of the season. And this moment speaks to the series’ position of devaluing non-traditional religious beliefs by “resolving” the cult through its destruction.\nThe Sinner may be read as a challenge to accepted narratives of crime, but its conclusion offers the same message evident in other texts within the genre: challenges to the prevailing frameworks will be neutralized.\nWith this positioning of crime and religion in tension, we also stumble upon a deeper question: why do we seek explanations for crime yet so often fail to take the same approach with faith?\nClicking on the Ko-fi banner at the top of this page (just below my bio) will give you the option to buy me a metaphorical “coffee”: it will take you to a personal funding page where you are given the opportunity to show your support for my work by donating a small amount of money (i.e., the price of a cup of coffee).\nNomos Journal is open and ad-free, so even the smallest amount of funding in the form of donations from my column’s readers and followers is greatly appreciated! Thank you!", "pred_label": "__label__POS", "pred_score_pos": 0.8904649019241333}
{"content": "Clinical Challenges in Wound Care\nChronic wounds are a challenge to wound care professionals and consume a great deal of healthcare resources. Chronic wounds have a complex pathophysiology and contain polymicrobial infections existing as a cooperative community that is resistant to antibiotic therapies. Healthcare providers have relied on conventional culture methods which fail to provide an accurate diagnosis of the microbial interactions or representation of microorganisms within a wound.\nThe Wound+ Solution\nPatients Choice Laboratories advanced DNA analysis allows for absolute identification of microorganisms. The Wound+ method provides insight into microorganisms contributing to polymicrobial infection, quantification and resistance gene identification. Wound+ delivers swift results with pinpoint accuracy leading to desired outcomes, lower costs and an improved patient experience.", "pred_label": "__label__POS", "pred_score_pos": 0.6035503149032593}
{"content": "Yeast and human Eme1 protein, in complex with Mus81, constitute an endonuclease that cleaves branched DNA structures, especially those arising during stalled DNA replication. We identified mouse Eme1, and show that it interacts with Mus81 to form a complex that preferentially cleaves 3'-flap structures and replication forks rather than Holliday junctions in vitro. We demonstrate that Eme1-/- embryonic stem (ES) cells are hypersensitive to the DNA cross-linking agents mitomycin C and cisplatin, but only mildly sensitive to ionizing radiation, UV radiation and hydroxyurea treatment. Mammalian Eme1 is not required for the resolution of DNA intermediates that arise during homologous recombination processes such as gene targeting, gene conversion and sister chromatid exchange (SCE). Unlike Blm-deficient ES cells, increased SCE was seen only following induced DNA damage in Eme1-deficient cells. Most importantly, Eme1 deficiency led to spontaneous genomic instability. These results reveal that mammalian Eme1 plays a key role in DNA repair and the maintenance of genome integrity.", "pred_label": "__label__POS", "pred_score_pos": 0.8779190182685852}
{"content": "You already pay enough in taxes.\nYou pay enough in taxes. Yet, the federal government is considering a significant increase in the gas tax to pay for new construction projects. This is wasteful and unfair.\nThe gas tax already takes a toll on those who can least afford it, especially Hispanics. On average, Latino families earn about $18,000 less than white, non-Latino families. We will carry the burden of a higher gas tax.\nBut it's not just the cost. Much of the money raised through gas taxes is used on unnecessary construction rather than the essential projects. You're left paying the bill for politicians to come up with ways to spend your money.\nThe gas tax doesn't need to be raised. Instead, lawmakers should remove costly barriers to construction projects and use the funds they have wisely. Remind your lawmakers you shouldn’t have to pay a higher gas tax, and sign the petition urging them to oppose it!", "pred_label": "__label__POS", "pred_score_pos": 0.9972628951072693}
{"content": "Abstract\nBACKGROUND AND OBJECTIVES: Though child abuse is prevalent and detrimental, health care providers fail to screen for abuse at sufficient rates to detect or preempt events. Current child abuse screening tools lack brevity and usefulness in clinical settings. To validate the Pediatric Hurt-Insult-Threaten-Scream-Sex (PedHITSS) screening tool, a 5-item questionnaire designed to detect and prompt provider investigation into child abuse in clinical settings, the PedHITSS was compared to the Conflict Tactics Scale: Parent-Child Version (CTSPC) screening measure. METHODS: Participants included 422 pediatric patients (n=242 nonabused; n=180 abused subsample) recruited from an ambulatory care setting, a medical center at-risk referral clinic, or homeless shelter clinic. Parents were asked to complete a cross-sectional survey, including PedHITSS and CTSPC questionnaires. Concurrent validity of PedHITSS was tested with 242 participants identified as nonabused. Construct validity was assessed with 180 participants previously identified as victims of child abuse. RESULTS: Concurrent validity between the CTSPC and PedHITSS was strong, rs=.70 (P<.01). Sensitivity and specificity for correctly identifying abuse victims (≤12 years) was optimal at a cutpoint of one or greater. There was no significant difference in sensitivity and specificity of HITSS and CTSPC in correctly identifying victims of child abuse. CONCLUSIONS: This study indicates that PedHITSS performs as well as CTSPC in identifying and differentiating victims and nonvictims of child abuse. PedHITSS allows health care providers to confidently screen and report suspected cases of child abuse and serves as a mechanism to confirm abuse status through validated means.\nASJC Scopus subject areas Family Practice", "pred_label": "__label__POS", "pred_score_pos": 0.7357903718948364}
{"content": "Some of the most difficult classroom topics for educators to address are current events. How do we approach this news in a way that connects to our content while also allowing opportunities for both discussion and engagement?\nThis webinar will share virtual resources that can be used to address current events through a civics lens. The Lou Frey Institute will discuss its weekly Civics in Real Life series, which uses civics concepts to explore current events in a one-page, student-friendly, image-rich text. This includes hyperlinks to related content and a closing activity that encourages reflection and engagement.\nThe webinar session will discuss ways in which this resource can be integrated into both face-to-face and virtual instruction while also discussing the use of the free Civics360 content platform as a means of building foundational knowledge through a virtual resource.", "pred_label": "__label__POS", "pred_score_pos": 0.6259064674377441}
{"content": "When reflecting on 2018, it is pleasing to consider all of the WPO’s involvement in a myriad of programs, including: education, exhibitions, conferences and social media. I encourage reading of the December WPO newsletter for further details on this involvement and development.\nI trust we have kept members informed and aware of the positive strides being made in the packaging industry across the globe. I thank the WPO Executive Team for their passion and for a job well done.\nWe look forward to serving the global packaging fraternity in 2019. I encourage you to be involved at whatever level you can, wherever you are. Together we will continue to ensure that we reduce packaging waste, reduce food waste, and ensure more are informed and educated in the power of packaging.\nOn behalf of the WPO executive Team, I wish you all a wonderful New Year, and wish you and your families a rewarding, prosperous and fulfilling 2019.\n*Pierre Pienaar is President of WPO pierrepienaar3@gmail.com +61 421 606 028 Skype Pierre Pienaar linkedin.com/in/pienaarpierre Facebook Pierre Pienaar\nforrás: wpo.org 2019.01.07", "pred_label": "__label__POS", "pred_score_pos": 0.842710018157959}
{"content": "Prolotherapy\nThis is a therapy that focuses on joint, ligament and tendon sources of pain. This therapy is highly effective at stimulating the recovery of joints that are unstable and are sources of referred pain.\nMost forms of musculoskeletal pain due to chronic degeneration or trauma originate with joint, ligament or tendon damage. Even muscle spasm can be created by joint issues. Prolotherapy is a highly effective treatment for restoring joint function and reducing pain.\nThe therapy consists of locating and anethsetizing the area and injecting a solution containing dextrose into the area triggering a physiological response resulting in tissue repair.\nPRP Therapy\nPRP therapy is an alternative approach to healing ligament and tendon injuries, using Platelet Rich Plasma (PRP). PRP contains large amounts of bioactive proteins, which initiate healing in connective tissue, promote growth of new blood vessels, and stimulate the healing process.\nThe first step in PRP Therapy is taking a small amount of blood from a patient. The blood is then placed in a spinning centrifuge, which automatically produces the PRP. PRP is then injected into the injured area, stimulating the tendon or ligament, which causes mild inflammation that triggers the healing process. As a result, new collagen is developed. When this collagen matures, it begins to shrink, which tightens and strengthens the tendons and ligaments in the injured area.\nPatients can see a significant improvement in their symptoms. PRP therapy can strengthen injured tissue up to 40%, and may eliminate the need for other treatments, such as medication or surgery.", "pred_label": "__label__POS", "pred_score_pos": 0.580786943435669}
{"content": "A recently conducted 3D printing statistics report by Sculpteo suggests that the majority of the engineering companies use 3D printing technology for manufacturing wherein 51% of the respondents were affirmative of using the same. It is quite fascinating that about 63% of the respondents believe that 3D printing, a subset of rapid prototyping will play a significant role in manufacturing and business context.\nThe massive majority of 80% is convinced that they have saved time utilising the technology. The infographic is an indicator of the rising trend of using time-saving, cost-cutting technologies to manufacture rapidly at mass levels.\nSeveral studies indicate similar predictions and convey that the technology is now widespread in a lot of manufacturing and engineering procedures. Sphinx Worldbiz offers great potential to reap from 3D printing for the manufacturers across industries and provide scalable resources dedicated to the customer’s team and enhance manufacturing performance by manifold.", "pred_label": "__label__POS", "pred_score_pos": 0.9209031462669373}
{"content": "Using entertainment to revive and preserve product value\nImplications - The meat industry has shown that using creativity can offset detrimental press and scrutiny. By transforming the way a product is packaged and used, a commodity losing consumer appeal due to changes in a consumer value, such as health, can be revived by flirting with another value, such as entertainment.", "pred_label": "__label__POS", "pred_score_pos": 0.9905347228050232}
{"content": "Back to\naccreditation.\nTraining in thoracic ultrasound is mandatory for Respiratory Medicine trainees prior to completion of CCT (and preferably prior to ST5). Until now the JRCPTB Respiratory Medicine Curriculum has mandated this is via completion of the Royal College of Radiologists Focused and Level 1 Thoracic Ultrasound pathway.\nRespiratory trainees have struggled to complete this due to the requirement to attend ‘\nat least one session per week over a period of no less than 3 months, with approximately five scans per session performed by the trainee’.\nThe pleural community have called for a recent change in curriculum and the British Thoracic Society have created a comprehensive training pathway for thoracic ultrasound that was published in 2020. This pathway provides guidance for all stages of ultrasound training – from novice to expert – and redirects the training responsibility from Radiologists to specialist Respiratory Physicians.\nThis document also recognises that other specialties – such as Intensive Care and Acute Medicine – are gaining competence in thoracic ultrasound and that trainees may be exposed to a greater degree out of hours.\nA link to the document is here.\nOutline\nThe first thing to note is that this pathway is\ncomplex and comprehensive. The document is worth reading several times.\nThe curriculum provides guidance for\n4 operator pathways and requirements for progressing to each stage. These include: Emergency Primary Advanced Expert\nEach\noperator pathway is then separated into capabilities in practice (CiP) levels: Level 1– entrusted to observe only with no provision of clinical care. Level 2– entrusted to act with direct supervision within the room. Level 3– entrusted to act with indirect supervision – supervisor may not be present in the hospital but contactable via electronic means and able to attend the bedside. Level 4– entrusted to act unsupervised. Level 5– able to supervise and train others.\nThere are numeric and assessment requirements for each operator pathway and level within the pathway.\nThese steps are not necessarily linear and once level 4 is achieved in one operator pathway, scans may be used to progress within the next pathway.\nEmergency Operator\nThe aim of this operator pathway is to ensure there is a clinician out of hours capable of identifying a significant sized pleural effusion – measuring 5cm in size.\nThe key elements to this level is to be able to distinguish between different anatomical structures and recognise limitations and boundaries of their practice.\nCurriculum: Pathway: Primary Operator\nPrimary operator is now the equivalent to Level 1 RCR Thoracic US. It is the expected level that\nRespiratory Trainees should achieve by ST5 level and aims at identifying commonly encountered pathologies including: Smaller effusions Complex effusions Consolidated lung Pleural thickening\nThe trainee will be required to attend a dedicated and accredited course for Primary Thoracic US.\nThe aim of this pathway now is to make this level more achievable for Respiratory Trainees and integrate it into departmental teaching.\nCurriculum:\nThe BTS provide two separate training pathway guides for either:\nTrainees progressing from Emergency Operator level. Trainees seeking Primary Operator accreditation without prior experience. Pathway progression from Emergency Operator: Standalone pathway for Novices: Advanced Operator\nAdvanced level is aimed at clinicians with regular pleural practice or a dedicated service.\nThey should have a minimum of 2 years at Primary level with evidence of ongoing practice in the field. It is aimed at the identification of more complex pathology including:\nPneumothorax identification Diaphragmatic paralysis Artefact interpretation including B lines Ultrasound guided procedures including drains and thoracoscopy\nIt is not clear how this level will integrate with clinicians of other specialties who are already regularly performing thoracic ultrasound to identify more complex pathology.\nCurriculum: Pathway: Expert Operator\nExpert operators are expected to be using advanced ultrasound modes (M mode and colour doppler) and likely to be a pleural specialist. Expected common practice would involve:\nAssess diaphragmatic function, movement and thickening during respiration. Greater proficiency in US guided procedure. Pleural and lung biopsy – including pneumothorax induction for medical thoracoscopy.\nIt is appreciated that there will be existing practitioners who will not not be expected to gain formal sign off but must establish their level of expertise with a regional mentor.\nCurriculum: Pathway: Maintenance of Competency\nOngoing practice is required for all disciplines to maintain competency. Local mentors may request supporting evidence (e.g. DOPS) if there is concern over capability.\nExpected number of scans for maintenance of competency:\nEmergency operator – 5 scans per year. Primary operator – 20 scans per year. Advanced operator – 30 scans per year. Expert operator – 70 scans per year.\nThe new BTS guidance is a lengthy and complex guidance but aims to encompass all levels of ultrasound practice from novice to expert. The aim is to ensure Respiratory trainees achieve the primary operator level without the difficulties currently faced. The expectations for primary operator level 4 (independent practice) are highly achievable and the availability of local mentors within Respiratory Medicine should streamline the process.", "pred_label": "__label__POS", "pred_score_pos": 0.643937349319458}
{"content": "A person convicted of a DUI may have a consequent criminal record. However, the duration of the existence of the record will depend on the state’s expunction or non-disclosure rules. A DUI conviction may remain on a criminal record indeterminately except in states that allow it to be removed or non-disclosed.\nGenerally, a DUI conviction may stay on one’s driving record for a minimum of five years. However, every state has its own law and the duration may vary.\nAre you charged with DUI? Are you in need of legal help? Contact the Law Office of Reuven J. Epstein\nIf you or a loved one is charged with a DUI and are in need of legal help, then DUI attorneys from the Law Office of Reuven J. Epstein can help. We listen to your concerns, and answer your questions and keep you informed about the case. For effective and efficient DWI defense in NY, call 845-459-0002 or 800-579-1605 and schedule a consultation with our skilled and experienced DWI defense lawyers.", "pred_label": "__label__POS", "pred_score_pos": 0.8528317809104919}
{"content": "Salary is typically determined by comparing market pay rates for people performing similar work in similar industries in the same region.\nSalary is also determined by leveling the pay rates and salary ranges established by an individual employer.\nThe accounts must be audited unless ASIC grants relief.The DBMS provides various functions that allow entry, storage and retrieval of large quantities of information and provides ways to manage how that information is organized.to keep and maintain records of the dates and hours your employees work for you and how much they're paid.Database designers typically organize the data to model aspects of reality in a way that supports processes requiring information, such as (for example) modelling the availability of rooms in hotels in a way that supports finding a hotel with vacancies.A database-management system (DBMS) is a computer-software application that interacts with end-users, other applications, and the database itself to capture and analyze data.\nLarge or small businesses have a vital role to play as taxpayers but also as employers.", "pred_label": "__label__POS", "pred_score_pos": 0.5782470703125}
{"content": "Making Your Dog Your Companion by Berger Blanc Suisse Puppies for Sale -\nMaking Your Dog Your Companion by Berger Blanc Suisse Puppies for Sale\nCompanion Animals\nYour Berger Blanc Suisse puppy will make a great companion animal and has the perfect temperament to be an emotional support animal. Unlike a service dog, a companion dog has no specialized training, but is simply there to provide companionship and psychological support. Emotional Support Dogs may perform activities such as aiding those who struggle with severe anxiety, ADHD, depression, learning disorders, PTSD, or even physical ailments such as high blood pressure.\nPrivileges\nUnder the Fair Housing Act, companion animals are allowed in all housing, including “no-pet” housing. Companion dogs are also allowed to fly with their owner on any airplane. In addition, you cannot be charged extra for either of these things. However, unlike service dogs, they cannot enter restaurants or supermarkets.\nRegistration:\nYou do not need any specific certification or license to register your Berger Blanc Suisse puppy as a companion dog. The only proof you need is a letter written by a licensed medical professional stating that you require an emotional support dog. The letter, including their signature and recent date, must specifically recommend that your dog will provide mental and/or physical aid to you. Emotional support dogs don’t require any specialized training, but they should be well behaved and under control so they aren’t causing harm or disturbance to those around you.\nWhile there is no need to officially register your companion animal, it is often helpful to go online and register your dog as an Emotional Support Animal to help deal with landlords or employees. You can also buy your dog a specific vest indicating that they are an Emotional Support Animal. However, note that this vest is different than a service dog vest or certified therapy dog vest.", "pred_label": "__label__POS", "pred_score_pos": 0.8767346739768982}
{"content": "Lung Cancer\nPhase III data from the LUX-Lung 8 head-to-head trial, evaluating Gilotrif versus erlotinib in patients with advanced squamous cell carcinoma of the lung, demonstrated superior improvement in progression-free survival with Gilotrif.\nThe trial demonstrated that Gilotrif (afatinib) significantly reduced the risk of disease progression by 18 percent when compared to erlotinib and delayed tumor growth (PFS by independent review: 2.4 vs. 1.9 months; HR=0.82; p=0.043). Overall survival data are not yet mature.\nTreatment with Gilotrif showed improvement in the secondary endpoint of disease control rate compared to erlotinib, 45.7 vs. 36.8 percent, respectively (p=0.020). Objective response rate was 4.8 percent in the Gilotrif arm compared to 3.0 percent in the erlotinib arm (p=0.233).", "pred_label": "__label__POS", "pred_score_pos": 0.6366303563117981}
{"content": "Discorso dell’Ambasciatrice Mariangela Zappia, Rappresentante Permanente dell’Italia presso le Nazioni Unite, al Dibattito Aperto in Consiglio di Sicurezza su \"Towards the 5th Anniversary of the Youth, Peace and Security Agenda: accelerating implementation of resolution 2250 and 2419\" ---\nItaly thanks the Dominican Republic for organizing this open VTC on a topic - the full involvement of youth - which is of great importance for promoting international peace and security, all the more in these particularly challenging times.\nYoung people are a vital driver for peace, change, and prosperity. Their specific sensitivity and forward-looking approaches, their natural desire for justice and inclusion, as well as their prominent motivation, enthusiasm and energy can meaningfully contribute to building and sustaining peace, providing long-term sustainable solutions and fostering conflict prevention and reconciliation.\nIn this spirit, five years from the launching of the Youth, Peace and Security Agenda through UNSCR 2250, Italy remains strongly committed to its implementation. From the outset, we have fully supported the Youth 2030 Strategy and we were the first Member State to provide financial support to the Office of the SG’s Envoy on Youth after her appointment. In our vision, youth policies represent the best link between the Peace and Security Agenda and the 2030 Agenda. To support this view, Italy is conducting a multi-country initiative in partnership with UNDESA for “Promoting sustainable peace through national youth policies” , which is currently under implementation in 3 countries and includes the constitution of national and local youth led “Youth, Peace and Security Civil Society Coalitions”.\nYoung people can contribute to peace processes in multiple ways, from monitoring ceasefires to resolving local-level disputes, building relationships across social divisions and shaping peace agreements. However, as highlighted in the Report of the Secretary General, in spite of a growing awareness of young people’s role in peace and security, young people continue to be excluded from decisions that will directly impact their present and future prospects for peace. They continue to face significant structural barriers to the participation in the decision-making, and many young peacebuilders report that their participation is not welcomed by the public opinion or by those in positions of power, pointing to an overall disregard for their work. This is especially true for young women, who face multiple and intersecting forms of discrimination and marginalization.\nIt is essential to ensure that young people have a say in peace discussions, as along with other vulnerable categories, such as women, elders and people with disabilities, they account for many of those adversely affected by armed conflict. Over two billion of the world population is under 24, 90% of which is in developing and vulnerable countries, whereas one in four young people are affected by violence or armed conflict.\nItaly has constantly engaged in empowering young people and enabling them to make their voices heard. Every year, since 2017, the Italian Government has been appointing two Youth Delegates who - through a nation-wide advocacy action as well as by participating in UN meetings - help promote the active participation of the youngest generations in decision-making, peacebuilding and reconciliation processes. Furthermore, in 2019 we dedicated our contribution to the Trust Fund in support of the UN Department of Political Affairs and Peacebuilding to initiatives in support of the participation of women and youth in peace processes.\nIn the same spirit, in preparation of the next COP26, Italy is organizing the youth event “Youth4Climate 2020: driving ambition”, which will focus, inter alia, on the impact of climate change on peace and security.\nIn the firm belief that there is a strong link between peace, security and the respect of human rights, Italy considers fundamental not only to ensure the protection of all human rights for young people, but also to strengthen their active role in the promotion of human rights within the societies. Italy is a member of the Human Rights Council’s core group for the resolution \"Youth and Human Rights\" which aims at promoting new initiatives for an effective, structured and sustainable participation of youth in relevant decision-making process.\nItaly is especially convinced of the need to encourage natural synergies between the Women Peace and Security and the Youth Peace and Security Agendas. Both women and youth face similar challenges to their meaningful participation in the decisionmaking, and share common vulnerabilities. The interplay between these Agendas is key: the combination between age and gender discrimination makes young women especially vulnerable, and gender mainstreaming is particularly needed to promote a paradigm shift. Due to the gendered perception of young people, peace and security interventions targeting young people, like those aimed at promoting their participation, tend to prioritize young men. While there is no doubt that young women are engaged in a variety of activities in building and sustaining peace, their role and contribution is often neglected and under-recognized, which perpetuates their marginalization.\nAgainst this background, in December 2019 we the Ministry of Foreign Affairs and International Cooperation of Italy invited several representatives of youth organizations to take part in a High-Level Seminar on “Strengthening Women’s Participation in Peace Processes: What Roles and Responsibilities for Member States?”, which was organized in Rome in collaboration with UNWOMEN. Furthermore, within the implementation of our Third National Plan on Women Peace and Security, we funded the “2020 Torino Forum for Sustaining Peace: Women and Girls at the Frontlines of Peace”, to be organized by the United Nations System Staff College (UNSSC) with a focus on the meaningful participation of women and girls in conflict prevention, and which will also take into consideration the complementarities of the WPS and YPS agendas.\nItaly remains committed to play its part in order to bring forward the full implementation of the YPS agenda and foster its synergy with the WPS Agenda.\nThank you.", "pred_label": "__label__POS", "pred_score_pos": 0.6662349700927734}
{"content": "We studied prospectively the effect of antenatal care on the obstetric performance of teenagers seen at a university teaching hospital over a 14-month period. When the obstetric complications among the teenagers were compared to their older counterpart, there were significantly higher complication rates, especially anaemia, preterm delivery, low birth weight and neonatal admission. After controlling for utilisation of antenatal care, significant differences were observed only in the incidence of low birth weight babies. In conclusion, this study has shown that the poor obstetric outcome of teenage pregnancy is related to non-utilisation of prenatal care rather than their biological age.", "pred_label": "__label__POS", "pred_score_pos": 0.94181889295578}
{"content": "High-resolution microscopic imaging\nThe direct visualisation of diesel sprays using high-resolution microscopy can give novel insight into the complex processes involved in the initial stage of spray formation.\nThe light source and imaging optics are optimised to produce shadowgraphic images of sprays with unprecedented sharpness. Sub-micron resolutions and ultra-short exposure times allow the observation of previously unreported shearing instabilities and the stagnation point on the tip of diesel jets.\nAn oblate spheroidal cap was observed for a wide range of conditions, which may consist of residual fuel from the previous injection. These findings suggest that vapourised fuel may remain trapped in the injector holes after the end of the injection process, and would support the theory that the formation of deposits in the holes of diesel injector nozzles may be linked to the degradation of such residual fuel.\nUltra high speed microscopic video\nThe complex interaction between the spheroidal cap and the jet that follows were observed using an ultra high-speed camera, operated at up to 50 million images per second.\nAlthough still apparent, the spheroidal cap is much less distinguishable at evaporating conditions. At elevated in-cylinder temperatures the spheroidal cap is in vapour state, and can be observed due to the refraction of the light caused by density gradients.\nA vortex ring motion within the vapour phase was identified, and resulted in a slipstream effect, which led to a central ligament being propelled ahead of the liquid jet. This phenomenon had been reported in the literature, but had remained unexplained until our research.", "pred_label": "__label__POS", "pred_score_pos": 0.9202175736427307}
{"content": "What happens when you light a candle in the dark? Does darkness flee or does light fill the space. Even the shadows dance when a candle is lit.\nA dear friend shared this quote the other day and it really encouraged me to reflect. \"Everything changes when you start to emit your own frequency rather than absorbing the frequencies around you. When you start imprinting your intent on the Universe rather than receiving an imprint from existence.\"\nAm I absorbing? What frequencies and energies am I absorbing? What types of situations am I putting myself into? When I am in these areas, what am I absorbing? Is it a positive space? When I am scrolling through farcebook and am killing time, what am I absorbing? Am I sharing my light? Do I emit positivity? Do I emit healing? What am I sharing with the Universe?\nOur thoughts and actions change (imprinting intent) based often from our surroundings and how the things of the world are impacting us. Will you choose to spread a frequency that may be unsettling? Or are you going to share an intent that can change the world?\nYou have the power. You can share an intent that could start a revolution. It could change the world. YOU are that powerful. It really isn't a secret, but the society we live in allows us to forget.\nEverything changes when we shine our own light. Our lights are beautiful. There is a principle in Hawaiian Shamanic practice called \"Makia\", energy flows where attention goes. What light are you shining? Is it a bright light of your own special unique frequency? Or is it a frequency from worldly things?\nI encourage you to be a light.\nStart emitting.", "pred_label": "__label__POS", "pred_score_pos": 0.8894399404525757}
{"content": "There has been remarkable progress on object detection and re-identification (re-ID) in recent years which are the key components of multi-object tracking. However, little attention has been focused on jointly accomplishing the two tasks in a single network... Our study shows that the previous attempts ended up with degraded accuracy mainly because the re-ID task is not fairly learned which causes many identity switches. The unfairness lies in two-fold: (1) they treat re-ID as a secondary task whose accuracy heavily depends on the primary detection task. So training is largely biased to the detection task but ignores the re-ID task; (2) they use ROI-Align to extract re-ID features which is directly borrowed from object detection. However, this introduces a lot of ambiguity in characterizing objects because many sampling points may belong to disturbing instances or background. To solve the problems, we present a simple approach \\emph{FairMOT} which consists of two homogeneous branches to predict pixel-wise objectness scores and re-ID features. The achieved fairness between the tasks allows \\emph{FairMOT} to obtain high levels of detection and tracking accuracy and outperform previous state-of-the-arts by a large margin on several public datasets. The source code and pre-trained models are released at https://github.com/ifzhang/FairMOT. (read more)PDF", "pred_label": "__label__POS", "pred_score_pos": 0.6159123778343201}
{"content": "A virtual Working Group Meeting of the Focal Persons of the D-8 Health and Social Protection (HSP) Programme on COVID-19 pandemic was held on 16 April 2020. The purpose of the meeting was to provide a platform for coordinating D-8 response to combat the pandemic.\nThe meeting was attended by delegations of Health Ministries of D-8 member States as well as representatives from Chatham House, Global Women Leaders in Health, WHO and ILO. Dr. Safi Muhammad Malik, Director General Ministry of National Health Services, Regulations and Coordination, was the focal point for Pakistan. Director General (EC&OIC) Mr. Tariq Karim, in his capacity as Pakistan’s Commissioner for the D-8, also attended the meeting.\nIn his remarks, D-8 Secretary General Dato’ Ku Jaafar Ku Shaari stated that the world was facing an unprecedented challenge posed by the COVID-19 pandemic. While appreciating responses of the member States to combat the pandemic, the Secretary General emphasized the need for greater multilateral cooperation. He stated that it was a time that required innovative, decisive and coordinated measures to save and secure lives of 1.1 billion people in D-8 member States. He urged the member countries to enhance their cooperation to combat the pandemic.\nIn his country statement, Dr. Safi Muhammad Malik highlighted various steps taken by the Government of Pakistan to combat the pandemic, including through various preventive measures such as necessary lockdowns, closing of schools and banning public gatherings, screening and testing, provision of PPE, surveillance of cases, expansion of isolation facilities, and information campaign. These steps were effective as Pakistan was still in the containment phase. He also mentioned about Prime Minister’s relief package of $ 8 billion launched for vulnerable groups.He highlighted the need for cooperation among member States through; harmonization of standards in travel and trade; mobilization of resources to develop core health capacities; building and dissemination of information; and development of partnership with international agencies.\nIn his intervention, Pakistan’s Commissioner for the D-8 highlighted the need for greater cooperation among D-8 member States to cope with the pandemic, including through existing D-8 mechanisms like D-8 HSP. Stating that the pandemic has unfolded an unprecedented global health & economic crisis, he highlighted Prime Minister Imran Khan’s call for ‘Global Initiative on Debt Relief’ for developing countries to enable them to free up resources to combat the disease and shore up economies. He also reaffirmed Pakistan’s commitment to the D-8 for collective welfare of the people of D-8 countries.\nThe participants agreed to hold regular round tables for D-8 HSP and constituted two working groups to deal with the COVID-19 pandemic, i.e. implementation monitoring and resource mobilization.\nPakistan is a founding member of the D-8. Other members include Bangladesh, Egypt, Iran, Indonesia, Malaysia, Nigeria and Turkey.\nIslamabad\n16 April 2020\nLast modified: April 16, 2020\nOur foreign policy is one of friendliness and goodwill towards all the nations of the world.", "pred_label": "__label__POS", "pred_score_pos": 0.6557815670967102}
{"content": "Hair Loss Thyroid hormones affect hair follicles as well and because they have a short life span (as they have stem cells), low hormones affect them majorly. These hormones do not the follicles to regenerate and that results in excessive hair fall and slow hair growth. If your hair becomes a lot patchy and coarse, consider it as a probable sign of hyperthyroidism.", "pred_label": "__label__POS", "pred_score_pos": 0.5761479735374451}
{"content": "Abstract\nT-lymphocyte migration under flow is critical for immune responses, but the mechanisms by which flow modulates the migratory behaviors of T-lymphocytes remain unclear. Human peripheral blood T-lymphocytes (PBTLs), when stimulated with phorbol 12-myristate 13-acetate (PMA), stretched their cell bodies dramatically and moved along the flow direction. In contrast, stromal cell-derived factor-1α-stimulated PBTLs deformed and migrated in a random manner. Here we elucidated the molecular mechanisms underlying flow-induced directionality and deformation of PMA-stimulated PBTLs. PMA primed PBTLs for polarization under flow, with protein kinase C (PKC)-δ enriched in the leading edge, PKC-βI in the microtubule organizing center, and PKC-βII in the uropod and peripheral region. PKC-δ regulated cell protrusions in the leading edge through Tiam1/Rac1/calmodulin, whereas PKC-β regulated RhoA/Rho-associated kinase activity and microtubule stability to modulate uropod contractility and detachment. Our findings indicate that PKC-δ and -β coordinate in the cell leading edge and uropod, respectively, to modulate the directionality and deformability of migratory T-lymphocytes under flow.\nKeywords deformability directionality migration PKCs T-lymphocyte ASJC Scopus subject areas Molecular Biology Genetics Cell Biology", "pred_label": "__label__POS", "pred_score_pos": 0.8661160469055176}
{"content": "Virtual Private Networks (VPNs) are valuable digital products that can assist users to visit blocked sites, conceal their location, or encrypt information among other features. However, most people are not aware of how they function, what they do, as well as how to use them. This article addresses all these questions about VPNs for beginners who may lack this information.\nThe common question most people ask is how do VPNs work?\nThis technology creates a computer-generated link between a device and a server. This virtual cable is responsible for creating a tunnel that encrypts any information that is transferred through it. The importance of the data encryption facilitated by VPNs is the fact that it bars hackers, internet service providers, administrations, or other computer users from viewing your digital footprint.\nThe expressvpn torrenting for beginners have three core components, which are security protocols, encryption, and servers. The security protocol is responsible for safeguarding the data that is conveyed through the server. This function is achieved through the creation of a protected connection as well as the determination of the kind of encryption the VPN will employ.\nConcerning the encryption component, it is imperative to note that it works in tandem with the security protocol. This component protects your data by encrypting it such that hackers or any other third party cannot decode it. Common VPNs for beginners mainly use the AES 128 and 256-bit encryption keys.\nConclusion\nLastly, it is common to find most providers citing their possession of multiple servers as crucial to their effectiveness. If you utilize a VPN, your information is first received by its server before being relayed to the intended one. This is crucial because when you request a server for a website, data is continuously relayed to and fro over the specific connection. In the presence of a VPN, the user’s request is conveyed to the server while personal data is only exchanged between the device and the VPNs server. This action explains how VPNs help you remain anonymous on the web.", "pred_label": "__label__POS", "pred_score_pos": 0.9615947604179382}
{"content": "Does it matter who files for divorce first in Utah?\nOver the years of serving the local community, we have found that many people are concerned if there are any benefits to being the first one to file for a divorce. In a technical sense, it does not truly matter who is the first to file for dissolution. We say this because the divorce process will move forward just the same, the end resulting in the same way. Another way of thinking about this is that the court system is going to process the case in their typical fashion regards of who files first. There are potential benefits however on a personal level. These benefits can be valuable to certain individuals but are determined by their unique circumstances. The difference between filing first or responding can be simply thought of like the difference between an offensive or a defensive approach.\nPotential benefits of filing a divorce\nWhen a person files for a divorce they are known as the petitioner. Given your specific needs and concerns, being the petitioner comes with a few advantages.\nYou have time to consult with as many family law attorneys as you wish. Having a successful divorce can depend greatly on finding a law firm that fits your needs. Requesting a consultation allows you to meet face to face with a legal professional and get an overall feel for how well your case will be handled by that firm. Once the divorce matter has been filed the respondent only has 30 days to respond. This can lead to a situation where they are crunched for time to find someone to represent them. As the petitioner, you can file your case when it is convenient for you. This can put you in a place where you are filing when you know you are not in the middle of holidays, or a busy time at work. This will put you in a position where you can focus more time and attention on your case. Finally, you have an opportunity to better prepare for the financial implications that can come with a divorce. Divorce or other family law concerns can be quite disruptive to our personal lives. By controlling when your case is filed you can help ensure that you are prepared for these changes. Speak with a legal professional\nEven if a dissolution of marriage is the right choice for you, it can still come with new challenges. If you live in Utah we invite you to contact Burton Family Attorneys to speak with a legal professional and schedule a consultation. During this meeting, you can have your questions answered and your concerns addressed.\nDisclaimer: Using this site or communicating with Burton Family Attorneys through this site does not form an attorney/client relationship. This site is legal advertising only. Do not rely on the information on this website as an alternative to legal advice from your attorney or other professional legal services providers. If you have any specific questions about any legal matter, you should consult your attorney or professional legal services, providers.", "pred_label": "__label__POS", "pred_score_pos": 0.5527704954147339}
{"content": "A will is essential at every stage of your life. Your will provides you with the opportunity to distribute your property, establish care for your children and otherwise express your wishes upon your death. A will is necessary if you intend to leave property to somebody besides a blood relative, such as a domestic partner, a friend or a charity. If you die without a will, the court determines how your property is distributed, who cares for your children and even what happens to your beloved pet — decisions that might not reflect your desires. At Miriam Davidson, Esq., we can draft a valid will that ensures your intentions are honored.\nAs your life changes, so might your estate plan. You may need to update your will throughout your life. We draft valid codicils that address changes in your financial situation, marital status, numbers of children, philanthropic interests and general lifestyle decisions.\nIf you have minor children or disabled adult children, your will allows you to make decisions about their future care, especially crucial if you are a single parent or if both parents die in a common incident. If you do not name a guardian, the court will appoint a guardian for your children and can make decisions adverse to your ultimate parenting goals. If you have a disabled family member, you will want their financial and medical needs met. You can also make arrangements for your pets’ care in your will, including naming a guardian who will take responsibility for your pets.\nDrafting this important document requires more than filling in a form. If a court determines that your will is invalid, your desires will not be honored upon your death. We meticulously draft your will and consider all aspects of your estate plan. We review your family arrangements, financial situation and philosophical goals to guide you in making the best estate planning decisions, and draft your will accordingly.\nWe can also assist in real estate transactions for your property. Anxiety often accompanies the excitement of buying or selling your home, condominium, or cooperative apartment. At Miriam Davidson, Esq., we skillfully represent you from offer to sale and work to ease your concerns. We conduct smooth and precise transactions during all stages of the home buying and selling experience:", "pred_label": "__label__POS", "pred_score_pos": 0.9576882719993591}
{"content": "ABSTRACT\nWe report a case of a 76-year old female presenting with symptomatic severe hypercalcaemia, and subsequently diagnosed with late onset SLE due to the presence of anaemia, leucopenia, antibodies of antinuclear (ANA), anti-dsDNA, and also kidney impairment. Serum levels of FGF23 and intact-parathyroid hormone (iPTH) were low in this patient. Serum calcium, FGF23 and iPTH levels responded to steroids, which occurred simultaneously with disease activity. On follow-up, the faster increase in FGF23 than in parathyroid hormone suggested that FGF23 might be involved in the pathogenesis of hypercalcaemia in SLE.", "pred_label": "__label__POS", "pred_score_pos": 0.5637950301170349}
{"content": "This webinar looks at the intersection between Life Cycle Thinking (LCT), Life Cycle Assessment (LCA) and Circular Economy (CE). CE provides a strategic framework for closed-loop material flows and a gateway to LCT, whilst LCA complements CE by assessing environmental impacts. These concepts and tools are particularly relevant to the waste sector, which has a crucial role managing waste streams and keeping resources in use.\nAs Aotearoa New Zealand transitions from a linear ‘take-make-waste economy’ to a Circular Economy, it will become increasingly important to assess change impacts, avoid burden shifting and understand trade-offs. A critical part of a product life cycle is the ‘end of life’ phase – dealing with waste. One of the key Circular Economy strategies identified by the Ellen MacArthur Foundation (EMF) is to ‘design out waste and pollution’, accompanied by ‘keep products and materials in use’ and ‘regenerate natural systems’.\nThis webinar discusses opportunities for the use of LCA to assess and improve New Zealand’s waste systems in the context of product stewardship. It will also provide some real-world examples relevant to the New Zealand waste management and resource recovery to demonstrate linear vs circular systems.", "pred_label": "__label__POS", "pred_score_pos": 0.8862049579620361}
{"content": "The Centre of Research Excellence for the Development of Innovative Therapies for Psychiatric Disorders (CREDIT)\nCREDIT has a single goal: Discovering and creating novel treatments to empower those with some of the most disabling mental disorders.\nWhat We Do\nCREDIT supports change in two ways:\nPursuing multiple lines of evidence to rapidly hone in on beneficial medications and lifestyle treatments Helping to grow the practical requirements – including resources, clinical trial networks, and guidelines – that can see new discoveries reach actual use.\nThis work requires diverse minds, generous collaboration, and a mindset of innovation. And it includes conversations with a strong cross-section of government, research, healthcare professionals, and the community.\nBenefits to come for clinicians and researchers National trials registry Key discoveries, in plain English National library of rating scales Advertising chances for community to access clinical trials Guidelines The Problem\nDespite the dedication of mental health professionals, some of our foremost medications for conditions like bipolar disorder have not changed in decades – not because they are perfect, but because we have not found better alternatives.\nCurrently, this dearth of treatment options leaves, for instance, full remission rates for psychosis at just 25%, and for depression, just 3 out of 10. In other words: if diagnosed with depression, you may have only a 30% chance of quickly finding a suitably effective treatment regime.\nWe find this unacceptable.\nThat’s why we are on a mission to discover new possibilities for potential treatments, by weaving together:\nPopulation data Key biological pathways for disease development Untapped potential of existing medications Clinical trials – that vital process for both testing and generating leads.", "pred_label": "__label__POS", "pred_score_pos": 0.6976181864738464}
{"content": "Rights:http://creativecommons.org/licenses/by/3.0/nz/ Creative Commons GNU GPL Allow modifications Allow commercial use\nAbstract:\nForest carbon farming offers customary landowners an alternative livelihood to socially and environmentally unsustainable logging, through the sale of carbon offset credits. REDD+, the global forest carbon scheme to address deforestation in developing countries, has attracted scholarly criticism for the risks it poses to communities. Critics warn that REDD+: (1) benefits may be captured by elites, (2) threatens forest-dependent livelihoods, (3) reduces local forest governance, and (4) a results-based payments mechanism can undermine conservation. Community-owned forest carbon farming may mitigate these risks by empowering communities to manage forest resources locally. The Loru project in Vanuatu is the first of its kind, and Indigenous landowners legally own the carbon rights and manage the carbon project. This thesis examines the community ownership and the social impact of the Loru project on its Indigenous project owners, the ni-Vanuatu Ser clan. The thesis uses a ‘semi’-mixed-methods approach, based primarily on interviews conducted in in Espiritu Santo, Vanuatu with Indigenous landowners and supplemented with quantitative data from a monitoring exercise conducted by the author. Grounded in social constructivism, the thesis makes a genuine attempt to decolonize the research process, adopting a self-reflexive approach. The research finds that the project is leading to positive social and economic impacts at the community level. Further, the Loru project is legitimately community-owned and driven, meaning it adapts effectively to the local context. Overall, the findings suggest that implementing REDD+ through a multi-scalar institutional network and building local capacity could mitigate the risks of REDD+ to forest communities.", "pred_label": "__label__POS", "pred_score_pos": 0.8197948932647705}
{"content": "Mars once had salt lakes that went through wet and dry phases similar to those on Earth, according to a study\npublished in the journal Nature Geoscience.\nThis indicates that the red planet’s climate ‘dried out’ a long time. According to the researchers, over 3 billion years ago, the lake that was present in\nGale Crater — a rocky basin that is being explored with NASA’s Curiosity rover since 2012 — underwent a drying episode possibly linked to the global drying of Mars.\nAccording to the researchers, including those from Texas A&M University in the US, liquid water on Mars may have become unsustainable and evaporated as the planet’s atmosphere and the pressure of the surface became thinner.", "pred_label": "__label__POS", "pred_score_pos": 0.784102201461792}
{"content": "If you have been a long time reader of this blog (especially in 2008), you will recall countless entries about the gap problems which have plagued the LIRR. Late yesterday afternoon, the agency sent out a press release to announce some great news. Gap incidents decreased by 35% in 2009. Here are the complete details:\nGap accidents at the MTA Long Island Rail Road declined by 35 percent in 2009 compared to the prior year; and by 56 percent compared to 2007.\n“We’ve made a concerted effort to address the gap issue and we think those efforts are contributing to these significant reductions in the number of incidents,” said LIRR President Helena E. Williams. “Our efforts will continue. Safety is our No. 1 concern at the LIRR. We remind customers to take responsibility for their own safety when exiting and entering trains. Put your Blackberry away, turn off your IPod and stow your cell phone for that moment. Your safety depends on it.”\nIn 2009, there were 77 gap incidents, down from 119 incidents in 2008 and 175 in 2007.\nThrough 2009, the LIRR expended approximately $27 million in gap mitigation efforts. An additional $12.3 million will be spent through 2012 addressing the gap by completing platform modifications, installing threshold plates on M3 and C3 cars, and the use of special platform conductors.\nThe LIRR’s multifaceted approach to gap mitigation includes a comprehensive customer education/awareness ‘Be TrainSmart’ Safety campaign; installation of platform edgeboards and shifting of platforms and track to reduce the gap; retrofitting of trains cars with wider threshold plates; and platform stencilings, expanded station signage and celebrity announcements advising customers to be mindful of the gap.\nCurrently, all the LIRR’s 836 newer M7 electric cars – the bulk of the LIRR fleet – have been fitted with new, wider threshold plates. Additional safety measures remain in place at Syosset Station, which is on a significant curve, including the use of special platform conductors, the call-ahead-for-assistance program, additional signage, platform edge lighting and platform cameras and monitors.\nThis is great news as for quite a period of time, this issue plagued the LIRR. I find it refreshing that this issue has not lead to many headlines in recent memory. Lets hope 2010 brings an even further decrease in gap incidents.\nxoxo Transit Blogger", "pred_label": "__label__POS", "pred_score_pos": 0.7602868676185608}
{"content": "Two years ago, a handful of us Wayne State graduate students explored the concept of transforming the city of Detroit from the urban sprawl model that currently takes hold into an Urban Village model of small local downtown-like districts and greater population density. The result was a 43 page document exploring these options and case studies.\nThe report begins as follows:\nAn urban village is a dense, self-sustaining, walkable community that has a strong residential component and includes a combination of retail, dining, leisure, and commercial uses. An urban village offers a ―place of belonging‖ that instills a sense of ―pride in the community‖ to both residential and business occupants. Initially, the urban village group focused on creating villages that had similar physical attributes of a modern day neotraditional development. It was later determined that the field research would consist of exploring the physical landscape of Detroit. The first group task was to divide the city into six sections. After dividing the city, each member took a section and visited the assigned areas to gather data. Each member also took several pictures of the designated sites to share with the rest of the group.\nThe group collectively discovered that some areas of the city were very vibrant while others were desolate. As we looked deeper into successful areas it was discovered that certain places were strong communities because of its residents and not necessarily its physical landscape or infrastructure. The focus shifted and the group began to identify potential village locations using criteria based on the social rather than the physical characteristics of a community. However, this scenario is more feasible in cities that have a growing population rather than a shrinking population, as is the case in Detroit. It will be important from a planning perspective to not only discuss the physical characteristics of urban villages but also the pulse of a village, which are the people and culture.", "pred_label": "__label__POS", "pred_score_pos": 0.6532589793205261}
{"content": "hifidiboاین کتاب را در اولین خریدتان با ۵۰٪ تخفیف یعنی ۳۳,۲۷۳ تومانارزانتر بخرید! درباره کتاب First Steps in Inclusion\nWith more parents of disabled children seeking a mainstream place for their child, educational professionals are increasingly being faced with the task of making these placements successful. For many this can be their first experience of including a child with significant difficulties. This book is aimed at all those, be they parents, teachers, learning support assistants, SENCOs, school managers, governors or LEA officers who are charged with ensuring that inclusion is effective both for individual children and for schools as a whole.Each chapter looks at the practicalities from a different perspective, focusing on the questions that need asking, the work that needs to be carried out before the child starts and practical steps that each person in the network can take to make sure that all those concerned are happy, are learning effectively and are fully included in the life of the school.", "pred_label": "__label__POS", "pred_score_pos": 0.9715364575386047}
{"content": "An offeror’s proposal to hire incumbent personnel–but pay those personnel less than they are earning under the incumbent contract–presents an “obvious” price realism concern that an agency must address when price realism is a component of the evaluation.\nIn a bid protest decision, the GAO held that an agency’s price realism evaluation was inadequate where the agency failed to address the awardee’s proposal to hire incumbent personnel at discounted rates.", "pred_label": "__label__POS", "pred_score_pos": 0.7936109304428101}
{"content": "If Doxycycline is not suitable for your destination, Atovaquone with Proguanil [link to Atovaquone with Proguanil] or its branded version Malarone [link to Malarone], might be. If appropriate, we can prescribe these for you.\nAs well as taking malaria tablets, you must take other measures to protect yourself against malaria when in a malaria area. These involve avoiding being bitten by a mosquito in the first place.\nYou should use insect repellent such as DEET, sleep under a mosquito net that's been treated with insecticide, and wear long-sleeved shirts and trousers in the evening.", "pred_label": "__label__POS", "pred_score_pos": 0.9999449253082275}
{"content": "Kabatereine, Narcis B; Brooker, Simon; Koukounari, Artemis; Kazibwe, Francis; Tukahebwa, Edridah M; Fleming, Fiona M; Zhang, Yaobi; Webster, Joanne P; Stothard, J Russell; Fenwick, Alan; (2006)\nImpact of a national helminth control programme on infection and morbidity in Ugandan schoolchildren. Bulletin of the World Health Organization, 85 (2). pp. 91-99. ISSN 0042-9686 DOI: https://doi.org/10.2471/blt.06.030353 Permanent Identifier\nUse this Digital Object Identifier when citing or linking to this resource.\nAbstract\nOBJECTIVE: We aimed to assess the health impact of a national control programme targeting schistosomiasis and intestinal nematodes in Uganda, which has provided population-based anthelmintic chemotherapy since 2003. METHODS: We conducted longitudinal surveys on infection status, haemoglobin concentration and clinical morbidity in 1871 randomly selected schoolchildren from 37 schools in eight districts across Uganda at three time points - before chemotherapy and after one year and two years of annual mass chemotherapy. FINDINGS: Mass treatment with praziquantel and albendazole led to a significant decrease in the intensity of Schistosoma mansoni - 70% (95% confidence interval (CI): 66-73%) after one year and 82% (95% CI: 80-85%) after two years of treatment. Intensity of hookworm infection also decreased (75% and 93%; unadjusted). There was a significant increase in haemoglobin concentration after one (0.135 g/dL (95% CI: 0.126-0.144)) and two years (0.303 g/dL (95% CI: 0.293-0.312)) of treatment, and a significant decrease in signs of early clinical morbidity. The impact of intervention on S. mansoni prevalence and intensity was similar to that predicted by mathematical models of the impact of chemotherapy on human schistosomiasis. Improvements in haemoglobin concentration were greatest among children who were anaemic or harbouring heavy S. mansoni infection at baseline. CONCLUSION: Anthelmintic treatment delivered as part of a national helminth control programme can decrease infection and morbidity among schoolchildren and improve haemoglobin concentration.\nItem Type Article Faculty and Department Faculty of Epidemiology and Population Health > Dept of Infectious Disease Epidemiology\nFaculty of Infectious and Tropical Diseases > Dept of Disease Control\nPubMed ID 17308729 ISI 244193900004 Related URLs", "pred_label": "__label__POS", "pred_score_pos": 0.7206546664237976}
{"content": "Based on research from the U.S. Congregational Life Survey, the authors identify ten strengths found in vital congregations, including meaningful worship, welcoming new people, and focusing on the community.\nOfferings\ndata from the U.S. Congregational Life Survey, insight from a diverse group of congregations across the country\nBest For\nclergy and lay leaders\nCost\npurchase as a book\nSuggested Uses\nEvaluate your congregation's strengths by comparing your experiences to the data detailed in the resource. Enhance areas of your congregation by discussing examples in the book with a small group and applying similar steps.", "pred_label": "__label__POS", "pred_score_pos": 0.9994122385978699}
{"content": "From the Document: \"The Covid-19 [coronavirus disease 2019] pandemic led to market turmoil in mid-March. Large price movements prompted large margin calls from central counterparties (CCPs). This strained the liquidity positions of large dealer banks. Banks also hoarded liquid assets, possibly in anticipation of large margin calls. This exacerbated the liquidity squeeze. Nevertheless, CCPs remained resilient, vindicating the post-crisis reforms that incentivised central clearing. The procyclicality of leverage embedded in margining models might have played a role in the events of mid-March. These margin models are critical because they underpin the management of counterparty credit risk. Margin models of some CCPs seem to have underestimated market volatility, in part because they have relied on a short period of historical price movements from tranquil times. These CCPs had to catch up and increase margins at the wrong time, squeezing liquidity when it was most needed. Going forward, the interaction of CCPs with clearing member banks is critical ('CCP-bank nexus'). Importantly, actions that might seem prudent from an individual institution's perspective, such as increasing margins in a turmoil, might destabilise the nexus overall. Therefore, central banks need to assess banks and CCPs jointly rather than in isolation.\"\nReport Number:\nBIS Bulletin No. 13; Bank for International Settlements Bulletin No. 13\nAuthor: Publisher: Date:\n2020-05-11\nSeries: Copyright:\n2020 Bank for International Settlements\nRetrieved From:\nBank for International Settlements: https://www.bis.org/\nMedia Type:\napplication/pdf\nURL:", "pred_label": "__label__POS", "pred_score_pos": 0.5143566131591797}
{"content": "Abstract\nThis chapter offers insights from a 15-year partnership between a public university and local K-12 schools to explore how the facilitation of media literacy education (MLE) programs by university students can offer rewarding outcomes for both research and learning. The MLE program that serves as the case study for this chapter takes place at local elementary schools each spring in conjunction with an undergraduate communication course and includes interactive media analysis discussions as well as a culminating creative production activity. Reflections and written feedback from participating graduate, undergraduate, and elementary students emphasize the strengths of this pedagogical model for collaboration and learning while also acknowledging the practical constraints of such a partnership. By detailing the institutional-level support, instructional design, and practical implementation of this MLE program, the chapter enumerates the benefits and challenges of engaged research and service learning for advancing media literacy goals.\nTop Background\nA MLE service-learning initiative requires consideration of instructional design at multiple levels. Firstly, stakeholders must design a program that results in mutually beneficial outcomes for both the university and the K-12 participants. Secondly, the conceptualization of MLE must be made explicit so the curriculum design can foster such literacy. Together, the civic engagement and service-learning framework and the MLE approach provide the theoretical foundations and practical implementation strategies for the initiative’s design.\nKey Terms in this Chapter\nPublic Engagement: The sharing of resources and knowledge between experts and non-experts on topics of collective concern.\nIntellectual Community: A mutually recognized space of knowledge sharing.\nReflexivity: The process of considering the researcher’s own role in shaping the construction of knowledge.\nDesensitization: The reduction of an emotional response to stimuli such as media violence due to overexposure.\nService-Learning: An educational experience in which course content is coupled with community-based activities for the mutual benefit of students and the community.\nPedagogy: The theory and practice of designing a learning experience.\nMaterialism: Valuing the acquisition of possessions above social, intellectual, and spiritual pursuits.", "pred_label": "__label__POS", "pred_score_pos": 0.8474897146224976}
{"content": "Li-kang Weng\nCrowd equity funding has been generally understood as primarily referring to an intermediary platform by which an entity, through the use of an electronic intermediary platform such as the Internet [1], engage in a small-scale public equity funding from investors. Since there is currently no law or regulation that specifically regulates crowd equity funding in China, in order to avoid running afoul of the current provision in the Securities Law that “no organization and individual may publicly offer securities to the public without legal permission,” and avoid being deemed as “offering securities to non-specific targets,” this activity is referred to as “Internet-based non-public equity financing” [2] to more accurately reflect the crowd funding practices under the current laws of China. With respect to crowd equity funding, the current regulatory documents that have referential value in practice are the self-regulatory Administrative Measures for Private Equity Crowd Funding (Pilot) (Solicitation for Opinions) prepared by the Securities Association of China in 2014 and the parts regarding crowd equity funding in the Guiding Opinions on the Healthy Development of Internet-based Financing jointly promulgated by ten ministries and commissions, including the People’s Bank of China, in 2015. The former expressly notes the private placement nature of crowd equity funding and sets down rules on platform quality, qualification of investors and platform self-governance and management, but the draft Solicitation for Opinions has not yet been finalized officially. The latter requires crowd funding to be done through an intermediary platform, the party seeking financing must be a micro enterprise, it must faithfully disclose key information to investors through such intermediary, and it shall not mislead or defraud investors. In addition, crowd equity funding shall be regulated by the China Securities Regulatory Commission. As a result, the China Securities Regulatory Commission is expected to issue management regulations regarding crowd equity funding and should therefore be closely watched. Because the legal nature and positioning of crowd equity funding platforms remain unsettled before dedicated regulatory measures are released, the popularity of crowd funding activities has also led to a substantial number of legal disputes arising out of misunderstandings among the participants regarding their roles. This article seeks to discuss the rights and obligations associated with crowd equity funding platforms with the following three major approaches. 1. Legality of raising capital through equity financing platforms If one desires to conduct crowd equity funding activities in compliance with existing laws, the main thing is to avoid crossing the line into “illegal absorption of deposit from the public” and “illegal offering of securities” as discussed below: (1) Illegal absorption of deposit from the public According to the interpretation of the Supreme People’s Court, an act that constitutes illegal or de facto absorption of deposit from the public under Article 176 of the Criminal Law should meet all four of the following conditions: (i) Absorption of funds without the approval of the relevant agencies or failure to conduct through a legally compliant method of operations. (ii) Promotion to the public through the media, promotional events, flyers, SMS or other channels. (iii) A promise to return the principal plus interest, or rewards provided, within a specific period of time through cash, in-kind of equity. (iv) Absorption of funds from the public at large, i.e., nonspecific targets. Therefore, to avoid being deemed as illegal or de facto absorption of deposit from the public, conduct such as public promotions, promises to repay investments or provide rewards, or accepting funds from nonspecific targets should all be avoided. (2) Illegal offering of securities Article 10 of the Securities Law provides that a public offering of securities requires an approval from the China Securities Regulatory Commission, and the presence of any one of the following circumstances will be deemed a public offering: (i) Offering of securities to non-specific targets. (ii) Offering of securities to an aggregate of over 200 specific individuals. (iii) Other acts of offering under laws and regulations. A non-public offering of securities may not use advertising, public solicitation and methods that are de facto public offering. Pursuant to the above requirements, if a platform targets “specific” investors with no more than 200 investors per financing project and do not employ advertising, public solicitation and methods that are de facto public offering, it will not be deemed to as have engaged in a “public offering of securities” per Article 10 of the Securities Law. The First Intermediate People’s Court of Beijing rendered a closely-watched second instance decision [3] at the end of 2015 on the first crowd equity funding lawsuit, in which Beijing Fit Network Technology Co., Ltd. (the platform) had a dispute with Beijing Nomido Food and Beverage Management Ltd. (the party seeking financing) over their intermediary contract. The decision recognized the legality and validity of the “Agreement on Consigned Financing Services” entered between the parties on the ground that relevant regulatory documents do not prohibit the crowd equity funding conduct involved in this matter. 2. The legal relationship among the party seeking financing, the platform and the investor In general, a platform facilitates transactions and plays a role more similar to that of an intermediary. In the aforementioned case involving the dispute between Nomido Co. and Fit Network Technology, the First Intermediate People’s Court also concluded that the legal relationship reflected in the “Agreement on Consigned Financing Services” between the party seeking financing and the platform party is that of an intermediary contract. In practice, however, the investor does not only expect a platform to be a mere “information intermediary” but also be a guarantor of sorts as a “trust intermediary”. From the platform’s perspective, it is difficult to switch between the roles of a “information intermediary” and a “trust intermediary”. If a platform enters into an agreement in its own name with an investor directly, it is very likely that the legal relationship between the platform party seeking financing would be deemed as “agreement with a third party under one’s own name as authorized by the consignor”, which, under Articles 402 and 403 of the Contract Law, entitles the investor to assert rights against the platform if the party seeking financing fails to perform its obligations [4]. Currently, most crowd equity funding platforms adopt the “lead investment plus follow-on investment” model, which means that a professional investment institution will serve as the lead investor after doing its due diligence, and individual investors will then follow to share the risks and benefits with the institution. So the crowd equity funding platform not only helps in coordinating information but also become more involved in the matter as well, such as using the fee from the party seeking financing to directly invest in that party, thereby becoming the lead investor. However, such deep involvement from the platform is prone to giving a false impression to investors that the platform is a guarantor, which would inadvertently increase the risks assumed, thus it must be done in caution. 3. Obligation of a platform to disclose information to investors In practice, investors often participate in a crowd equity funding scheme due to trust in the platform rather than the party seeking financing. In case of any problem with the party seeking financing, the investors are likely to blame the platform first. Case in point, in June 2016, a crowd equity funding platform named 36Kr.com was reported to have suffered complaints from investors because the numbers in the latest financial statements disclosed by Hongli Energy, an entity recommended by 36Kr.com to investors, were drastically different from those at the time of a private placement at the end of last year. As a result, 36Kr.com was plunged into “allegations of fraud” over crowd equity funding [5]. Therefore, it is imperative for a platform to pay more attention to the regulatory aspect of recommendations and information disclosure to avoid disputes with its investors over any crowd funding project. In this regard, Articles 8 and 9 of the Administrative Measures for Private Equity Crowd Funding (Pilot) (Solicitation for Opinions) sets out the relevant obligations and prohibited conduct for platforms, including the necessary examinations on the legality of a financing project; measures taken to prevent fraud and, in case any fraud or any other circumstance that undermines the interest of investors is detected, the timely announcement of such and the termination of the relevant financing activities; the prohibition against making external guarantees or hold shares in trust; and the prohibition against leveraging the platform’s own advantages to obtain investment opportunities or mislead investors. In conclusion, before the relevant regulations for crowd equity funding are released by the China Securities Regulatory Commission, they can only be legally conducted in practice by staying within the scope of “internet-based non-public equity financing.” The platform should take care to avoid crossing into prohibited areas such as “illegal absorption of deposit from the public” and “illegal offering of securities.” In addition, the platform shall disclose the relevant information faithfully and stay away from becoming deeply involved in the projects, which means playing the role of an “information intermediary” rather than a “trust intermediary.” [1] Please compare the Guiding Opinions on the Healthy Development of Internet-based Financing promulgated by the People’s Bank of China, the Ministry of Industry and Information Technology and the Ministry of Public Security on July 14, 2015. [2] Compare the Circular Special Inspection of Institutions that Conduct Internet-based Equity Financing Activities (Zheng Jian Ban Fa [2015] No. 44) adopted by the General Office of the China Securities Regulatory Commission on August 3, 2015. [3] The second instance civil decision in the matter involving the disputes between Beijing Nomido Food and Beverage Management Ltd. and Beijing Fit Net Technology Co., Ltd. over their intermediary contract [2015-One-Chong-Min-(Shang)-Zhong-No.0922]. [4] Wei Chen and Chongying Li, Analysis of Focused Issues of Internet-based Non-public Equity Financing Business and Prevention of Legal Risks Ð Perspectives from Recent Disputes over Financing Projects Involving Some Platforms, published in the WeChat ID for the Hot Legal Topics on Legal and Commercial Net on June 29, 2016. [5] Feifan Li, 36Kr.com Plunged into the Vortex of “Alleged Fraud” for Equity Crowd Funding Projects, published on TMT post (http://www.tmtpost.com/1786615.html) on June 13, 2016.", "pred_label": "__label__POS", "pred_score_pos": 0.5838491320610046}
{"content": "IOM, the UN Migration Agency, has found that the trip to Libya is reportedly costing more for a larger proportion of migrants from Sudan and Nigeria.\nIn 2016, 60 percent of Nigerian respondents and 41 percent of Sudanese respondents reported paying between USD 1,000 and 5,000 for their journey to Libya.\nThis increased to 71 percent of Nigerian respondents and 64 percent of Sudanese respondents in the first few months of 2017. This data was collected through Flow Monitoring surveys conducted among 1,314 migrants.\nThis data is included in the Round 8 DTM Migration information package, which presents data collected between December 2016 and March 2017. It highlights that 381,463 migrants were found to be present in Libya during that period.\nThe package provides a holistic overview of resident and mobile migrants in Libya. It presents data on migrants’ demographic characteristics, journeys, intentions, relations with the host community, documentation status, educational and vocational backgrounds. The data builds on Libya 2016 Migration Profiles and Trends, which was published in March.\nThe information package provides detailed information on where 381,463 migrants from 38 different nationalities are in Libya. It also includes a dataset, which for the first time, provides a quantification of migrants by nationality in each location. The regions of Misrata (66,660 individuals), Tripoli (53,755 individuals), and Sebha (44,750 individuals) are reported as hosting the largest number of migrants, while the main nationalities were recorded as Egyptian, Nigerien, and Chadian.\nRelations were found to be poor between migrants and the host community with multiple incidents of tension in 17 percent of Libya’s municipalities. However, in 33 percent of the municipalities, migrants were reported to have a positive impact on the local labour market, contributing to a stronger economy and more jobs.", "pred_label": "__label__POS", "pred_score_pos": 0.6381744146347046}
{"content": "Child Custody and Shared Parenting\nParents contemplating a divorce are sometimes confused by terms such as “sole custody,” “shared parenting,” “school placement parent,” “custodial parent,” “residential parent.” Some parents are under the misconception that “shared parenting” means the children must spend equal time with each parent.\nAs a parent contemplating divorce, it is important for you to understand the legal and practical differences between sole custody and shared parenting. In most cases, both parents are interested in co-parenting their children in a manner that allows the children to have significant contact with both parents. After all, neither parent is divorcing the children.\nWith over 30 years of experience in helping parents divorce with dignity, Attorney Linda J. Miller is committed to helping you and your spouse to effectively co-parent your children after the divorce. If appropriate, she will assist you in preparing a Shared Parenting Plan, outlining your post-divorce plans for sharing time with your children (including holidays), plan for the children’s financial stability, and plan for making future, post-divorce decisions on important matters such as the children’s health care and education.", "pred_label": "__label__POS", "pred_score_pos": 0.9264928102493286}
{"content": "Accession Number: AD1037367 Title: Advancements in DNA Vaccine Vectors, Non-Mechanical Delivery Methods and Molecular Adjuvants to Increase Immunogenicity Descriptive Note: Journal Article - Open Access Corporate Author: USAMRIID Ft Detrick United States Report Date: 2017-06-15 Pagination or Media Count: 35.0 Abstract:\nA major advantage of DNA vaccination is the ability to induce both humoral and cellular immune responses. DNA vaccines are currently used in veterinary medicine, but have not achieved widespread acceptance for use in humans due to their low immunogenicity in early clinical studies. However, recent clinical data have re-established the value of DNA vaccines, particularly in priming high-level antigen-specific antibody responses. Several approaches have been investigated for improving DNA vaccine efficacy, including advancements in DNA vaccine vector design, the inclusion of genetically engineered cytokine adjuvants, and novel non- mechanical delivery methods. These strategies", "pred_label": "__label__POS", "pred_score_pos": 0.9375242590904236}
{"content": "Wilting is the loss of turgidity of leaves and other soft aerial parts causing drooping, folding and rolling. Wilting is of three types:\nTemporary wilting –It is the temporary drooping down of leaves and young shoots due to the loss of turgidity during noon. It is verywell revised simply after the pace of transpiration diminishes joined by the renewal of water around root hairs. Incipient wilting –Partial and temporary loss of turgor in a plant that occurs in the presence of adequate soil moisture and is associated with excessive water loss through transpiration. Permanent wilting –It is that state in the loss of turgidity of leaves when they do not regain their turgidity even when being placed in a suitable atmosphere", "pred_label": "__label__POS", "pred_score_pos": 0.5776687860488892}
{"content": "The determination that an individual debtor is not entitled to be freed from responsibility for one or more of its prepetition claims; the denial of a debtor of the injunctive relief it seeks, via the Code’s discharge provisions, when that debtor files for bankruptcy. In certain cases, even if an individual debtor receives a discharge, certain types of debts are not dischargeable, a few examples being when the debtor obtained money or property by false pretenses or fraud, when the debtor owes money for inflicting willful and malicious injury on another or another’s property, or when the debtor is obligated for domestic support. In some Chapter 7 cases, a debtor may not be entitled to a discharge of any of its debts, for instance if the debtor knowingly and fraudulently made a false oath or account in a case, if the debtor has refused to obey a lawful order of the court, or if the debtor has already received a discharge within the eight-year period preceding the date of the filing of the petition in the case. Debtors that are not individuals are not entitled to discharge in Chapter 7 cases.\nBankruptcy Code §§ 523, 524, 727.", "pred_label": "__label__POS", "pred_score_pos": 0.6888741850852966}
{"content": "Abstract\nThis book will be a one-stop-shop for readers seeking information on biofibers that are sustainable and environmentally friendly and those that can replace the non-renewable synthetic polymer based fibers. Emphasis will be on fibers that are derived from agricultural byproducts and coproducts without the need for additional natural resources.\nASJC Scopus subject areas Engineering(all) Materials Science(all)", "pred_label": "__label__POS", "pred_score_pos": 0.9679589867591858}
{"content": "The dependability of power service is increasingly becoming a vital site location consideration. The storms which have plagued Northeastern Illinois over the last month have led to numerous power outages across the region. A few of these outages have extended over multiple days. Interestingly, none of the new business parks in Lincolnshire, Vernon Hills or Buffalo Grove experienced even temporary power disruptions due to these storms despite being in the direct path of some powerful winds. We attribute this to a combination of all underground utilities and the availability of electrical service from multiple sub-stations at many of these locations. While such a service is sometimes taken for granted, it is essential for any technology (power) dependent businesses.", "pred_label": "__label__POS", "pred_score_pos": 0.9754060506820679}
{"content": "CHAPTER 5 Treatment stages\nDifferential tooth movement, as previously defined, involves repositioning of the crowns of the teeth first, followed by root uprighting to the new crown positions. However, there is a prescribed overall sequence of tooth movements, in the correction of any malocclusion with Tip-Edge, that needs to be followed closely. It is basically very simple and goes as follows:\nStage Iis all about the anterior segments, which should be aligned, and any incisor spacing closed. They should also be corrected both antero-posteriorly and vertically (eliminating overjets, reverse overjets, increased overbites or anterior open bites). The archwires most commonly used will be .016 inch high tensile stainless steel, the resilience and flexibility of which is ideal for overbite reduction. Nickel–titanium auxiliary ‘under arches’ are frequently employed in the initial treatment visit, to assist in the alignment of instanding or rotated teeth. However, it should be noted that an ‘under arch’ runs beneath the main archwire, in the bracket slot, and never through the deep tunnels. Use of the deep tunnels in Plus is intended for Stage III only. Stage IIconcerns closure of any residual extraction spaces and seldom exceeds 3 or 4 months, except perhaps in first molar extraction cases. In non-extraction cases, it will obviously be very brief. However, it is important that centrelines should be coincident and correct before all the spaces are closed, since centreline discrepancies will prevent the attainment of a correct Class I occlusion. Also, towards the end of the stage, the first molars will require to be derotated in readiness to receive the rectangular archwires of the third stage.\nNormally .020 inch high tensile stainless archwires are preferred during this stage, since they offer easy free sliding through the molar tubes, yet have enough flexibility to correct molar rotation. However, the extra robustness of .022 inch wires may sometimes be indicated, such as when expanding maxillary crossbites, or when protracting second molars across first molar extraction spaces.\nStage IIIis the root uprighting phase, during which each tooth is torqued and tipped to its preadjusted values to complete the treatment. Previously, and with the Rx-1 bracket, this was achieved by the action of Side-Winder springs working against rectangular .0215 × .028 inch stainless archwires. The Plus bracket will use a deep tunnel nickel–titanium auxiliary archwire to do the same. The rectangular archwires will be identical />", "pred_label": "__label__POS", "pred_score_pos": 0.8344947695732117}
{"content": "Sumit Chopra, consumer research director at GlobalData, a leading data and analytics company, highlights four major innovation trends that are set to impact South Korea’s haircare sector in 2019 in terms of production, marketing and sales.\nNatural Wave\nConsumers in South Korea are seeking natural ingredients such as botanical/herbal extracts to use in their daily haircare products. In line with the current demand for natural products, manufacturers are introducing haircare products which are “free from” silicones, sulfates, parabens and artificial color and fragrances to foster consumer trust and loyalty. Hence, haircare products that go beyond their basic beautifying function are growing in popularity. For instance, France-based Klorane launched anti-yellowing shampoo with high levels of cyanocentaurein (a plant-based pigment with blue tints) in South Korea for white and gray hair.\nBeing Unique\nSouth Korean consumers are looking for innovative products, which offer an indulgent and relaxing experience. According to GlobalData’s 2018 Q4 Consumer Survey, 61% of South Korean consumers are willing to pay more for better and premium quality haircare and fragrance products. Therefore, manufacturers are capitalizing on this trend and offering products with special formulations and exclusive ingredients. South Korean beauty brand Skinfood launched Argan Oil Silk Hair Essence with unique ingredients such as argan oil, which helps in strengthening and softening the hair.\nMaking it Simple\nAccording to GlobalData’s 2018 Q4 Consumer Survey, 21% of South Korean consumers are willing to try new and time-saving haircare and fragrance products. Rising urbanization levels are inspiring busy South Koreans to look for simple and time-effective beauty regimens, leading to an increased demand for multi-functional products. Keeping this “more than one benefit” approach in mind, manufacturers are introducing a plethora of haircare products with multiple benefits. For example, Ryoe Korean launched Herbal Damage Care Hair Treatment mask, which helps in coating the hair with strengthening ingredients like camellia oil, and adds moisture and shine to strands immediately after the first usage.\nTargeting the Silver Segment\nIt is crucial for brands to persuade consumers about the effectiveness of anti-aging items as older consumers in South Korea resonate well with anti-aging products, particularly ones that highlight or strengthen white or grey hair. Haircare brands should seek to engage consumers through offerings that target specific hair issues such as thinning hair, dull hair and lack of hair volume, which are often related to aging. For example, Grafen launched Cold Booster in 2018 to tackle the issue of hair loss and other hair aging problems resulting from having a high scalp temperature.", "pred_label": "__label__POS", "pred_score_pos": 0.9542569518089294}
{"content": "Explore the Health Data Below: Youth Marijuana Use Youth drug use rates are declining in Lancaster County and the U.S.\nIllicit drug and alcohol use by youth increase their risk for injury, violence, HIV infection, and other diseases,\n9 and is related to lower academic achievement. 10 Since 2001, Lancaster County has seen a 34% decline in marijuana use among teens. 23.8% of students reported 30-day marijuana use in 2005, dropping to 15.7% in 2015. Marijuana use is lower among teens in Lancaster County than nationally, though comparable annual data have not been available since 2015. Footnotes\n9. Centers for Disease Control and Prevention. (2012). Alcohol and other drug use. Retrieved October 2, 2013, from: http://www.cdc.gov/healthycommunitiesprogram/overview/diseasesandrisks.htm\n10. Centers for Disease Control and Prevention. (n.d.). Alcohol and other drug use and academic achievement. Atlanta, GA: Centers for Disease Control and Prevention.", "pred_label": "__label__POS", "pred_score_pos": 0.9670232534408569}
{"content": "It's the most wonderful time of the year!\nThis season causes the most challenges for seniors. However, with these few tips, it will be easy to stay safe while still enjoying the joyous holidays:\nDress for warmth.Don't let indoor temperatures go too low and dress in layers. Wear warm socks, a heavy coat, a warm hat, gloves and a scarf. In very cold temperatures, cover all exposed skin. Fight wintertime depression.To help avoid feelings of loneliness, family members can check in on seniors as often as possible or send their loved one to adult day care; a short, daily phone call can also make a big difference. Eat a varied diet.It's recommended to consume foods that are fortified with Vitamin D, such as milk, grains and seafood options like tuna and salmon. Prevent carbon monoxide poisoning. Using a fireplace, gas heater or lanterns can lead to carbon monoxide poisoning. Ensure your safety by checking the batteries on your carbon monoxide detector and buying an updated one if you need to.", "pred_label": "__label__POS", "pred_score_pos": 0.8953920006752014}
{"content": "Citation:Slater, T. S., McNamara, M. E., Orr, P. J., Foley, T. B., Ito, S. and Wakamatsu, K. 'Taphonomic experiments resolve controls on the preservation of melanosomes and keratinous tissues in feathers', Palaeontology, [In press]. DOI: 10.1111/pala.12445\nFossils are a key source of data on the evolution of feather structure and function through deep time, but their ability to resolve macroevolutionary questions is compromised by an incomplete understanding of their taphonomy. Critically, the relative preservation potential of two key feather components, melanosomes and keratinous tissue, is not fully resolved. Recent studies suggesting that melanosomes are preferentially preserved conflict with observations that melanosomes preserve in fossil feathers as external moulds in an organic matrix. To date, there is no model to explain the latter mode of melanosome preservation. We addressed these issues by degrading feathers in systematic taphonomic experiments incorporating decay, maturation and oxidation in isolation and combination. Our results reveal that the production of mouldic melanosomes requires interactions with an oxidant and is most likely to occur prior to substantial maturation. This constrains the taphonomic conditions under which melanosomes are likely to be fossilized. Critically, our experiments also confirm that keratinous feather structures have a higher preservation potential than melanosomes under a range of diagenetic conditions, supporting hitherto controversial hypotheses that fossil feathers can retain degraded keratinous structures.\nThis website uses cookies. By using this website, you consent to the use of cookies in accordance with the UCC Privacy and Cookies Statement. For more information about cookies and how you can disable them, visit our Privacy and Cookies statement", "pred_label": "__label__POS", "pred_score_pos": 0.6459183096885681}
{"content": "During centrosome maturation, pericentrin is delivered to the centrosome co-translationally by a microtubule- and dynein-dependent process, as pericentrin mRNA is undergoing active translation near the centrosome.\nNewly formed tetraploid cells rapidly lose extra centrosomes acquired upon tetraploidization via asymmetric centrosome clustering during cell division and selective advantage of tetraploid daughter cells that inherit a single centrosome.\nBuilding on previous work (Conduit et al., 2014), and contrary to what was previously thought, it is shown that key centrosomal proteins are not recruited to centrosomes as part of large multi-protein assemblies.\nMicrotubules are nucleated by the centrosome of the primary cilium in the apical end-foot of neuroepithelial cells and inter-dependent microtubule and actin dynamics are required here to orchestrate delamination of newborn neurons.", "pred_label": "__label__POS", "pred_score_pos": 0.5519331693649292}
{"content": "Initially, AT&T wanted water towers and power lines to be included in the usual small cell antenna package of street lamps, traffic lights and poles. However, during the state’s recent legislative session, according to\nCleveland.com, the wireless giant agreed not to include them. Instead, the company wants to speed up the 5G network application process to a 90-day approval or denial, which would allow communities to “block the installation of new wireless antennas.”\nOpponents include Cleveland Mayor Frank Jackson, the Ohio Municipal League and the Ohio Municipal Electric Association. Jackson told\nCleveland.com that the 90-day limit would prevent “cities and villages from having an adequate say on where the antennas are installed.” Additionally, the Ohio Municipal League and the Ohio Municipal Electric Association are tasked with providing the language for the proposal for the session scheduled to end on Thursday, according to Cleveland.com.\nKent Scarrett, a spokesman for the Ohio Municipal League, told the news site that the time limit “would mean a municipality wouldn’t be able to conduct an environmental study or take other time-consuming measures before approving or rejecting the antenna.” He added that if the time rule is approved “local governments might challenge their constitutionality in court, claiming they violate home-rule authority.”\nIn a letter written to the legislation, Jackson urged for opposition to AT&T’s request, stating the measure would be “too broad and prevents local municipalities from having a say in rates, zoning, and maintenance issues as it relates to wireless infrastructure.”\nCleveland.com noted that if the measure is amended, it would “probably” be added into an existing bill. December 7, 2016", "pred_label": "__label__POS", "pred_score_pos": 0.5438845157623291}
{"content": "For 50 years, Sonny’s BBQ local pitmasters have served barbecue slathered in Southern Hospitality to millions of guests in America through its locations spanning the Southeast. Today, many of the older locations are now in markets where populations and demographics have shifted. Sonny’s is now using SiteZeus’ software solution to analyze the performance of existing restaurants, as well as to provide location intelligence for new locations as the brand grows.\nChallenge #1 Benchmarking locations across the nation\nOriginally, Sonny’s BBQ faced the challenge of creating an unbiased benchmark or grading system for its existing locations. Often decisions were influenced by opinions instead of facts. One team member might think a location was doing great, while another would disagree.\nSolution\nThe SiteZeus platform provides analysis for each location along with a comparison between actual revenues compared to projected revenues. This platform helps indicate if restaurants are performing up to their potential, underperforming, or even outperforming SiteZeus’ projected sales. If a store is performing $300K less than the predicted value, then that location will get flagged in the SiteZeus Quadrant Recommendations & Predictive Outliers as a location that should be reviewed and optimized. Sonny’s can use these meaningful insights to drill down into the analytics to uncover reasons why that location is underperforming.\n“SiteZeus allows us to make more informed sales projections. They have a built-in confidence meter that back tests itself to provide a percentage of accuracy that we can rely on as we expand across the nation.”\nAlex Regar, Business Intelligence Analyst | Sonny’s BBQ\n...Keep Reading\nTell us a bit about yourself to unlock the full article.", "pred_label": "__label__POS", "pred_score_pos": 0.7073785662651062}
{"content": "Abstract\nSpectrum sharing has been recognized as a key component for 5G and beyond wireless networks. Recent trials have revealed the business value of spectrum sharing via the licensed shared access model, wherein both the incumbent and the licensee operators are protected from harmful interference by sharing the available spectrum using long-term spectrum access agreements. Further increase in capacity gains can be achieved by exploiting dynamic spectrum access, where access is granted in shorter time intervals, and the Spectrum Access System, which is a more flexible version of traditional LSA. This article first hints at LSA-type spectrum sharing in regulatory and standards bodies, then proposes a few relevant scenarios that would take advantage of LSA, and finally presents an LSA system architecture and some enabling technologies for LSA/DSA/SAS. These include novel sensing, dynamic and radioaware resource allocation, and advanced cooperative communication techniques.", "pred_label": "__label__POS", "pred_score_pos": 0.9998688101768494}
{"content": "Make today’s workout simple! While a high-end, 5-star gym, state-of-the-art cardio equipment, and shiny, scratch-free weights can all increase fitness motivation, neither are necessary for a safe and effective workout! As a Certified Spin Instructor for nearly 10 years, I grew very accustomed to the Keiser M3+ bike and Precor Spinner bike. Both leading indoor cycling bikes are equipped with monitors featuring information such as, RPMs, calorie expenditure, distance, wattage, and HR. Then… the COVID-19 pandemic and resulting gym closures worldwide! As a Spin-obsessed, fitness enthusiast I was devastated. As a graduate student at the time, I was not in the financial position for a $2,000+ Spin bike… What did I learn from this experience? Simple workouts using minimal to no equipment can be just as effective and elicit the same feel-good emotions as a workout with an expensive indoor cycling bike at a gym. What did my “quarantine workouts” consist of? Outdoor running and power walking Hiking and observing nature’s simplicities Resistance bands, TRX, and by own body weight To name a few… Simple workouts leading to a big goal… My First Half Marathon! After the partial reopening of gyms in Washington state, Keiser M3+ and Precor Spinner bikes remain unavailable for me. On the bright side, I now have access to a simpler Schwinn bike at a local Anytime Fitness!\nNo monitor featuring RPMs, calorie expenditure, distance, wattage, or HR. Just me and the bike – and of course, the resistance knob too! What did I learn from this experience? “Monitor-less” indoor cycling bikes can create a greater mind-body, mindful ride! I am not distracted by the numbers flashing in front of my eyes and deeply connect my mind to my muscles and focus on my breath. I do still welcome the day I ride another Keiser M3+ bike and Precor Spinner bike… But just like stopping during a hike to appreciate the simplicity of nature, riding a more minimalist Schwinn bike can elicit feelings of gratitude and a deeper connection with the mind, body, and soul.", "pred_label": "__label__POS", "pred_score_pos": 0.9585395455360413}
{"content": "Contributor\n08 July 2020\nThe UK government has announced a support package of £1.57bn for art venues and heritage sites that have been struggling due to the impact of Coronavirus.\nThis announcement arrives a few days after the Miss Live Theatre campaign covered London’s National Theatre on tape as sign-on support for the performing arts.\nThe UK government’s support package has been described as ‘the biggest ever investment in UK culture’ and will comprise of a combination of grants and repayable loans that the government states will be ‘issued on generous terms tailored for cultural institutions to ensure they are affordable.’\nAdditionally, the money being provided will support the restart of employment in construction projects at various heritage sites that had initially been halted due to the pandemic.\nFunding will be available to organizations within the culture and heritage industries, including art galleries, theatres, music venues, independent cinemas, and museums.\nDetails concerning applications are expected to be shared within the coming weeks. However, anyone wishing to apply for aid will have to prove to the government that they contribute to wider economic growth in the UK.\nWhile the majority of the package will be spent in England £189m will be divided between devolved administrations, with £97m going to Scotland, £59m to Wales and £33m to Northern Ireland.\nCulture Secretary, Oliver Dowden has acknowledged the challenge currently facing the culture industry and said, “This massive investment shows our level of commitment.” The UK’s Prime Minister, Boris Johnson, described the industry as “the beating heart of this country,” adding, “This money will help safeguard the sector for future generations.”\nWhile some in the industry have welcomed the announcement Shadow Culture Secretary, Jo Stevens, has described the effort on Twitter as “too little too late.”\nRecently England has seen the reopening of pubs, hairdressers, theme parks, and cinemas, among others, despite concerns that customers will not adhere to social distancing rules. However, culture venues such as theatres remain closed.\nThe government is currently in the process of finalizing guidance for a phased reopening of the arts sector.\nThe Group Chief Executive of Ambassador Theatre Group recently shared that, ‘We now need to unite to restore audience confidence and work in close partnership with authorities to remount British theatre as soon as is appropriately possible.’", "pred_label": "__label__POS", "pred_score_pos": 0.9413144588470459}
{"content": "Are You Worried About A Frozen Shoulder Diagnosis?\nHave you been diagnosed with a ‘frozen shoulder?’. Perhaps you are experiencing long term pain in the shoulder and are simply worried about your potential diagnosis.\nA ‘Frozen Shoulder’, or scientifically named ‘Adhesive Capsulitis’ refers to a painful inflammation and stiffening of the shoulder joint. Its consensus definition is “a condition of uncertain etiology, characterised by significant restriction of both active and passive shoulder motion that occurs in the absence of a known intrinsic shoulder disorder.” It is relatively uncommon in the realm of shoulder injuries, but most frequently occurs in females between the ages of 40 and 60 years.\nMost commonly, those affected will have difficulty with tasks such as reaching their arm behind their back, reaching for their bra strap and reaching for overhead cupboards, in addition to often unrelenting pain in their shoulder and upper arm.\nThe following guide offers a detailed explanation of a Frozen Shoulder, along with key information you should know when receiving treatment. Due to its long term nature, it is important to receive sound early advice and appropriate exercise prescription to minimise your pain and shoulder dysfunction.\nMove Physiotherapy are your experts in treating shoulder pain. We offer longer consultations to comprehensively assess your shoulder pain, provide a detailed diagnosis and comprehensive treatment plan.\nWe have two locations. Our main clinic is based in the Gateway Centre in the Westfield Booragoon complex. This brand new clinic is equipped with state of art treatment rooms, a fully equipped rehabilitation gymnasium in a central and convenient location.\nOur second East Fremantle clinic is based inside the Fremantle Rowing Club. This satellite clinic has a beautiful waterfront location with newly constructed rooms, and a complete gymnasium that is shared with members of the Fremantle Rowing Club. This clinic comes fully equipped with change rooms and showers.", "pred_label": "__label__POS", "pred_score_pos": 0.7843776941299438}
{"content": "The Government aims to ensure no one is left behind in the move to digital payments, and argues that EU regulations have previously been a barrier to retailers offering cashback when people were not paying for goods or services.\nThe report states that the Government is considering changing the rules after the Brexit transition period ends at the end of 2020, freeing up more businesses to offer cash.\nThe COVID-19 pandemic has accelerated UK consumers’ move towards card payments and away from notes and coins, and banks have continued to announce branch closures, leaving fewer options for people who want to handle cash. This has been a particularly problem for those who live in remote areas.\nFull article:\nThe Guardian - Plan for UK shops to offer cashback without a purchase\nSign up to our newsletter to receive all the latest news and updates.", "pred_label": "__label__POS", "pred_score_pos": 0.9475386142730713}
{"content": "NO. When done properly colostrum can be successfully pasteurized to eliminate the same pathogens that can be found in the milk. These pathogens are even more dangerous in colostrum since these bacteria and viruses can easily pass through the gut wall along with the large proteins that impart immunity to the calf. Colostrum can be safely pasteurized at 140F for 60 minutes to remove all pathogens without significant damage to immunoglobulins. Colostrum pasteurization should be as much a part of herd biosecurity as milk pasteurization.", "pred_label": "__label__POS", "pred_score_pos": 0.8997387886047363}
{"content": "Economic Confidential, a publication of PRNigeria, on Sunday, released its Annual States Viability Index (ASVI).\nThe report shows that 7 states, led by Katsina, are insolvent as their Internally Generated Revenue (IGR) in 2019 were below 10 percent of their total federal allocation in the same year. IGR is generated through Pay-As-You-Earn Tax (PAYE), direct assessment, road taxes and revenues from Ministries, Departments and Agencies (MDAs). Last year, the ASVI revealed that only 10 Nigerian States were financially strong. The latest index shows that without the monthly disbursement from the Federation Account Allocation (FAA), many states would be unviable. It put the IGR generated by 36 states at N1.3trillion in 2019, compared to N1.1trillion in 2018. Lagos State IGR of N398bn in 2019 was higher than 20 States’ IGR combined, thus maintaining its number one position. Lagos received N270billion FAA, meaning its IGR (147 percent) was more. In the year under review, the Federal Capital Territory (FCT) Abuja generated N74billion against N30billion FAA. Ogun State generated N70.92billion IGR compared to N92billion FAA -representing 77 percent; Rivers generated N140billion against N219billion FAA – representing 64 percent; Kwara State generated N30billion compared to N80billion FAA – representing 38 percent. Kaduna State generated N44billion compared to N129billion FAA – representing 35 percent; Enugu State generated N31billion against N103billion FAA – representing 29 percent; Ondo State generated N30billion compared to N103billion FAA – representing 29 percent. Edo State generated N29billion compared to N108billion FAA – representing 27 percent; Anambra State generated N26billion against N98billion FAA – representing 27 percent; Cross River State generated N22billion compared to N99billion FAA – representing 25 percent. The report shows that in 2019, 10 states generated N894billion IGR, while the remaining 26 states generated N440billion. It confirms that most states have improved their IGR as only 7 generated less than 10 percent, against 17 states in 2018. For the weak 7 states, Katsina, the home state of President Muhammadu Buhari, tops the list. It generated N8billion IGR compared to N136billion FAA – representing 6 percent. Kebbi State generated N7.3billion compared to N100billion FAA – representing 7 percent; Borno State generated N8billion against N121billion FAA – representing 7 percent; Taraba State generated N6.5billion compared to N86billion FAA – representing 8 percent. Bayelsa, the home state of former President Goodluck Jonathan, generated N16billion compared to N176billion FAA – representing 9 percent; Yobe State generated N8.4billion against N88billion FAA – representing 9 percent; Gombe State generated N6.8billion compared to N75billion FAA – representing 7.5 percent. The poor states were advised to formulate initiatives for revenue generation. The report identified insurgency, kidnapping, banditry and herdsmen-farmers clashes, as some of the reasons for low income and investors’ fear. Only 3 states in the North earned above 20 percent IGR, while 10 states in the South recorded likewise. They are Lagos, Ogun, Rivers, Enugu, Ondo, Edo, Delta, Anambra, Cross River and Delta. Click to view/download full report", "pred_label": "__label__POS", "pred_score_pos": 0.8921465277671814}
{"content": "A school district's ability to raise local funds is classified as significantly more, slightly more, slightly less, or significantly less than the statewide average.\nStudent needs in a school district are classified as significantly higher, slightly higher, slightly lower, or significantly lower than the statewide average.\nEconomically disadvantaged students are those who participate in, or whose family participates in, economic assistance programs, such as the free or reduced-price lunch programs, Social Security Insurance (SSI), Food Stamps, Foster Care, Refugee Assistance (cash or medical assistance), Earned Income Tax Credit (EITC), Home Energy Assistance Program (HEAP), Safety Net Assistance (SNA), Bureau of Indian Affairs (BIA), or Family Assistance: Temporary Assistance for Needy Families (TANF). If one student in a family is identified as low income, all students from that household (economic unit) may be identified as low income.\nEnglish Language Learners (ELLs) are those who, by reason of foreign birth or ancestry, speak or understand a language other than English and speak or understand little or no English, and require support in order to become proficient in English and are identified pursuant to Section 154.3 of Commissioner's Regulations.\nThe need/resource capacity index, a measure of a district's ability to meet the needs of its students with local resources.\nRace or races with which the student primarily identifies as indicated by the student or the parent/guardian.\nStudents with disabilities are those who have been identified as such by the Committee on Special Education and are receiving services under the Individuals with Disabilities Education Act (IDEA). Students with disabilities include those having an intellectual disability; hearing impairment, including deafness; speech or language impairment; visual impairment, including blindness; serious emotional disturbance; orthopedic impairment; autism; traumatic brain injury; developmental delay; other health impairment; specific learning disability; deaf-blindness; or multiple disabilities and who, by reason thereof, receive special education and related services under the IDEA according to an Individualized Education Program (IEP), Individualized Family Service Plan (IFSP), or a services plan.", "pred_label": "__label__POS", "pred_score_pos": 0.5017451047897339}
{"content": "Abstract\nIn late 2014, a group of women who live in Tigers Bay and New Lodge came together to offer visual representations of their localities as a means of highlighting issues affecting interface areas of the 'post'-conflict city. A key critique of the Northern Ireland peace process agenda has been the exclusion of women in its formation and implementation (Ward, 2013). This photobook, which was created in the complex context of post-conflict Belfast, highlights women's experiences within their own locality. Its primary focus is encouraging women to become proactive agents in addressing the legacy of the Troubles, thereby promoting the inclusion of their vision in the political public sphere. These photographs represent issues that this group of womenwish to be taken forward as the peace process progresses. In a wider political culture of promoting external investment and economic growth in Northern Ireland, it is essential those communities most affected by the conflict remain central to adressing its legacy. This photobook aims to play a role in ensuring that this remains the focus of the post Good Friday Agreement political agenda.\nOriginal language English Place of Publication Coleraine Publisher Ulster University Number of pages 38 ISBN (Print) 978-0-9933177-9-8 Publication status Published - 2 Oct 2015 Keywords post-conflict collaborative photography women and peacebuilding The Troubles visual sociology", "pred_label": "__label__POS", "pred_score_pos": 0.9505674839019775}
{"content": "Research Area: Nuclear Hazards and Risks Researcher: David Reading, University of Southampton Partners: AWE Funders: AWE Outreach award\nThe Challenge\nNuclear forensics is dedicated to the characterisation of radiological and nuclear materials out of regulatory control. Its purpose is to determine the history of such nuclear material, for example its provenance and geolocation which determines the source and route of the material.\nThis project aims to determine the origin of uranium ore and its concentrates. These can vary from low uranium concentrations through to \"yellowcake\" which contains 70-90 % uranium. Ultimately the concentrate is fabricated into a fuel for nuclear reactors.", "pred_label": "__label__POS", "pred_score_pos": 0.9427475929260254}
{"content": "South Africa’s 24 marine protected areas (MPAs) are critical for the health of future fish stock. Yet their significance is not fully appreciated. From coastal residents and fishers through to government prosecutors and judges, a lack of understanding of the importance of these areas continues to hamper efforts to manage MPAs effectively. These are among the findings … [Read more...]\nYou are here: / Archives for sushi", "pred_label": "__label__POS", "pred_score_pos": 0.958304762840271}
{"content": "The global internet encompasses tens of thousands of interconnected networks which are run by governments, service providers, individual companies, universities and so on.\nOne of the components is hardware, which support the internet, such as routers, servers and smartphones. This network of networks can communicate thanks to open standards: anyone can create content and offer services. There are existing protocols that all devices connected to the internet must follow, such as the transmission control protocol and internet protocol.", "pred_label": "__label__POS", "pred_score_pos": 0.8168758153915405}
{"content": "DOMO Chemicals has expanded its THERMEC™ range of enhanced polymers, with the introduction of a cost-efficient product based on polyether ether ketone (PEEK), blended with a solid polymeric lubricant. The new solution, which is now available in India, has been specially developed to replace polyamide-imides (PAI), without impacting performance.\nTHERMEC™ K is an innovative experimental product that has been developed at DOMO’s Mumbai-based laboratory in India, a huge market for friction and wear resistant materials. The solution is suitable for numerous industrial applications, including bushings & bearings, aerospace parts, pump & valve components, medical instrument parts and food processing machinery components.\n“Generally speaking, the mechanical properties of PAI are higher than those of PEEK-based parts, due to the different types of polymers the material contains. But it is more expensive too,” explains Tushar Parida, Country manager India at DOMO. “However, through the careful formulation work of our Indian development team, we have been able to match the friction & wear performance and dry lubrication properties of PAI in a PEEK-based solution.”\nDOMO’s Mumbai team has shown that THERMEC™ K is suitable for numerous applications, especially when low wear, low coefficient of friction at temperatures of up to 200C° and resistance to high load-bearing conditions, is required. Furthermore, it grants a lower density of 1.32g/cm3, compared to a PAI solution of 1.42g/cm3.\nIn addition to offering comparable tribological properties to PAI, THERMEC™ K can be processed using a standard injection moulding procedure. This means that the use of complex cold injection moulding equipment followed by a lengthy steam curing process is unnecessary. THERMEC™ K offers a wide range of material property benefits that ranges from exceptional properties at elevated temperatures, chemical resistance, mechanical strength, strong wear and fatigue resistance, and dielectric strength.\nDOMO plays a growing role in the higher performance polymers market. The extensive THERMEC™ product range has been developed to meet the demands of specific application requirements. The enhanced polymers solution range features new solutions based on polyphthalamide (PPA): THERMEC™ N; polyphenylene sulfide (PPS): THERMEC™ S; and polyether ether ketone (PEEK): THERMEC™ K).", "pred_label": "__label__POS", "pred_score_pos": 0.653212308883667}
{"content": "Abstract : Bile acids are signaling molecules, which coordinately regulate metabolism and inflammation via the nuclear farnesoid X receptor (FXR) and the Takeda G protein-coupled receptor 5 (TGR5). These receptors activate transcriptional networks and signaling cascades controlling the expression and activity of genes involved in bile acid, lipid and carbohydrate metabolism, energy expenditure, and inflammation by acting predominantly in entero-hepatic tissues, but also in peripheral organs. In this review, we discuss the most recent findings on the inter-organ signaling and interplay with the gut microbiota of bile acids and their receptors in meta-inflammation, with a focus on their pathophysiological roles in obesity, type 2 diabetes, dyslipidemia and non-alcoholic steatohepatitis and their potential therapeutic applications.", "pred_label": "__label__POS", "pred_score_pos": 0.6283466815948486}
{"content": "Importers Used Second Scheme to Evade AD/CV Duties After First Discovered, CBP Finds\nSource\nAmerican Shipper\nPost Date\n11/20/2020\nIn a final determination under the Enforce and Protect Act, U.S. Customs and Border Protection has found substantial evidence that two U.S. importers evaded the antidumping duty order on carbon steel butt-weld pipe fittings from China by transshipping them through Vietnam. Among other things, CBP identified multiple sales contracts involving these importers with fine print indicating that transshipment was “to be allowed,” identified “vast inconsistencies” between the equipment purchase documentation provided by the importers and a response from the Vietnamese company, and found evidence suggesting that the importers shifted their business from Malaysia to Vietnam after the Department of Commerce’s determination of circumvention with respect to pipe fittings from China through Malaysia. As a result of this determination, CBP will take the following measures. - susp or continue to susp the liquidation of all entries imported by the importers that are subject to this case until instructed to liquidate - rate adjust those entries previously exted, change those entries to type 03, and continue suspension until instructed to liquidate - continue to evaluate the importers’ continuous bonds and to require single transaction bonds as appropriate The EAPA, part of the Trade Facilitation and Trade Enforcement Act, gave CBP a significantly expanded role in investigating AD/CV duty evasion and the authorities to match. Under CBP regulations implementing the EAPA any interested party, including competing importers and federal government agencies, may submit allegations that AD/CV duties are being evaded; e.g., by misrepresenting the goods’ true country of origin, submitting false or incorrect shipping and entry documentation, or misreporting the goods’ physical acteristics. CBP has broad authority to conduct investigations of these claims and can impose initial remedial measures that could interrupt a supply chain in as little as 90 days. Any final determination of evasion may be met with not only AD/CV duties but also other enforcement measures such as civil or criminal investigations.", "pred_label": "__label__POS", "pred_score_pos": 0.822651743888855}
{"content": "Through-life delivery support\nDelivering a major contract can be more complex than running a business: there are increasingly high levels of ambiguity, technical complexity, commercial pressure, people and cultural dynamics, procedural hoops and significant stakeholder and communications challenges compounding the “normal” project delivery challenges of time, cost and quality considerations.\nNowhere is this more evident and critical than during the project-defining mobilisation period where challenges and expectations are maximal, and maturity and capacity are fledgling. This can often result in projects being born with very significant challenges from which they never recover or, at best, consume enormous resources to regain an acceptable outcome.\nWe offer high-impact project facilitation services to ensure the leadership and governance groups have understood the challenges and defined a strategic success plan. From this point, we offer services including project and culture health checks; strategic facilitation; coaching and mentoring; behavioural-based safety programs; lean construction / continuous collaborative improvement methodologies; leadership development; mediation and conflict resolution services; and various skills development programs including time management, conducting effective meetings and communications.\nAgain, we think it makes sense for our clients to expect us to put some skin in the game and we are more than happy to link our commercial outcomes to those of our clients. We look forward to working with you on maximising the performance of your toughest projects.", "pred_label": "__label__POS", "pred_score_pos": 0.5857366323471069}
{"content": "Grayscale CEO says that Bitcoin will win because both a Trump or a Biden election victory would result in more “brrr” or the expansion of the US dollar supply.Whether it is a Democratic sweep led by Joe Biden or a Donald Trump reelection, Bitcoin (BTC) would likely thrive. Industry executives, including DCG and Grayscale CEO Barry Silbert, say both a Trump or a Biden win would buoy BTC.The optimistic stance of industry execs despite the glaring election risk comes after Grayscale’s Bitcoin study.Grayscale, a major cryptocurrency investment firm with $7.6 billion in net assets under management, released a study on Oct. 27 highlighting that the potential market for Bitcoin has significantly expanded in 2020.\nIn 2019, Grayscale discovered that 36% of investors in the U.S. were interested in investing in Bitcoin. This year, 55% of investors in the U.S. are looking at Bitcoin. The study reads:Interest is on the rise: More than half of U.S. investors are interested in investing in Bitcoin In 2020, more than half (55%) of survey respondents expressed interest in Bitcoin investment products. This marks a significant increase from the 36% of investors who said they were interested in 2019.The nearly 20% rise represents a substantial increase in mainstream awareness within a short period. It also coincides with the growing demand for Bitcoin from institutions following Bitcoin’s impressive 200%+ recovery since March.\nHigher mainstream awareness strengthening BTC\nThe strong fundamental factors behind Bitcoin and the rapidly growing demand could offset the election risk in the fourth quarter.For instance, a particularly positive statistic that shows the clear increase in demand for Bitcoin in 2020 is the rate at which individuals interested in BTC become actual buyers.According to Grayscale, out of the individuals that expressed the intent to invest in Bitcoin, 83% purchased BTC.\nThe researchers wrote:Among those who reported investing in Bitcoin, 83% have made investments within the last year, indicating that digital currencies are an increasingly attractive component of modern investment portfolios.The higher conversion rate from interested individuals to investors is important because Bitcoin’s potential market has rapidly expanded.What’s more, the potential market in the U.S. of around 32 million investors does not include other major markets like Europe and Asia.\nMeanwhile, the number of investors familiar with Bitcoin has also increased noticeably. The survey found that 62% of investors are now aware of BTC, compared to just 53% in 2019. The study said:Based on this year’s survey, the market of potential Bitcoin investors is 32 million strong — compared to 21 million investors just one year ago. This year, 62% of investors reported that they are ‘familiar’ with Bitcoin, compared to 53% in 2019.\nWhat is the biggest allure of BTC to investors?\nThe primary reason behind the attraction of Bitcoin remains its exponential growth potential. Yet, in the eyes of institutional investors, it is also a hedge asset.Bitcoin being a hedge asset against inflation and having demonstrated exponential growth potential makes it a compelling portfolio asset for both institutions and accredited investors.\nConsequently, the number of investors purchasing Bitcoin with a fraction of their capital or portfolio and building on top of existing positions has increased as well. The Grayscale research says:The factors that drove interest in Bitcoin last year resonated even more with investors in 2020. In 2019, 59% of survey respondents indicated that the ability to start with a small amount and increase their investment over time would be a motivating factor when considering Bitcoin investment products; in 2020, that number increased to 65%.\nThe clear spike in interest towards Bitcoin follows a continuous rise in inflows from institutional investors. As Cointelegraph reported, Grayscale added $300 million to its net AUM in one day on Oct. 23 as the Bitcoin price hit new yearly highs.", "pred_label": "__label__POS", "pred_score_pos": 0.5198194980621338}
{"content": "Accountability is a willingness to accept responsibility or be answerable for one’s actions and decisions. Unfortunately, embracing accountability can be intimidating, conjuring images of reprimand after something has gone wrong (“Who’s responsible for this?!”).\nWhile the experience may be uncomfortable at times, claiming accountability can one of the most important decisions in our personal and professional lives. Accountability is powerful because it orients individuals and teams toward taking personal responsibility (“How can I help achieve this goal?”), versus releasing responsibility to others (“That’s not my job.”).\n“We all had a job to do. We all held each other accountable. We all stepped up in our leadership roles. We [took] nothing for granted that year.”Vince Wilfork, New England Patriots, on winning Super Bowl XLIX\nHow to cultivate accountability\nHow do you pragmatically develop accountability within a team to sustain high performance?\nEnsure a baseline of integrity\nAccountability depends highly on\nintegrity. Team members will not be motivated to be accountable if they collaborate with people who say one thing but do another. In fact, team members may be incentivized to deflect accountability and shield themselves when a gap in integrity persists. Remove resistance to accountability\nThe three most common reasons people resist accountability are:\na lack of control, a lack of desire, and avoidance of risk. Here are the excuses you may hear from a team and how to overcome each. 1. “We would own this, but it’s out of our control.”\nIt is hard to be accountable when a team feels they are impacted by issues they cannot fix. Quantify the challenges outside your control and focus on leveraging influential relationships. Here’s how:\nConcisely tell the story (as a team) of the top 3 challenges outside of your control Work with project sponsors to drive urgency within their networks on key challenges Bring surrounding stakeholders into team meetings/cadences, emphasizing these challenges Encourage each team member to build relationships with surrounding teams and stakeholders to bring transparency to key issues 2. “We would own this, but some team members don’t really want to.”\nA team cannot gain traction when certain individuals do not want to take accountability. Seek to understand, engage, and act on feedback.\nApply active listening techniques to understand the resistant team members’ perspectives Engage every team member through directed feedback exercises (2-3 sticky notes per team member, encouraging feedback from the resistant team members) Agree on the top 2-3 priorities as a team and act on the feedback 3. “We would own this, but we don’t want a target on our backs.”\nSome teams sense that taking on ownership is too politically risky or may generate negative repercussions.\nIf this is true, ask yourself, “Do I really want to work in a place that discourages me, covertly or otherwise, from taking accountability?” Weigh the risks of taking accountability versus the benefits from doing so. While it may be saferto not take accountability for now, you may place yourself in a comprising position in the future. Proceed on the path that allows you to maintain your integrity and positively impact the situation at hand. If things turn out poorly despite acting with accountability, it may be a wake-up call that you are in the wrong environment. Celebrate individuals who take accountability\nPublicly recognizing teammates who own up to their actions when their plan fails is a powerful way to\nreinforce the desired behaviors. Openly discuss failures, ask teams to identify lessons learned, and thank people for demonstrating ownership of both the positive and negative outcomes of their decisions.\nAs they observe the distinction between the value of a person and the success or failure of a task, teams will be increasingly comfortable inviting critical feedback without feeling personally judged. More critical feedback leads to more successful outcomes and consistently higher performance.\nAccountability is critical for any team to enjoy consistent, rather than random, success. Accountability is closely tied to our ability to build relationships and actively listen to understand others’ perspectives. Start with a consistent and transparent demonstration of accountability. Over time, the expression of this accountability develops the team’s resiliency and fortifies their status as a high performing team.", "pred_label": "__label__POS", "pred_score_pos": 0.8446759581565857}
{"content": "Rodriguez, Michelle Natividad and Beth Avery. National Employment Law Project.\nThis paper examines the significant flaws in state occupational licensing criminal background check requirements. One barrier to employment that regularly appears in state occupational licensing laws is the blanket ban, which automatically disqualifies people with certain records. In response to this barrier and others, a comprehensive overhaul of licensing laws is recommended.", "pred_label": "__label__POS", "pred_score_pos": 0.9999649524688721}
{"content": "What is the optimal timing of surgical intervention following adult laryngeal trauma? Background: Airway management is paramount in cases of adult laryngeal trauma. Even with a secured airway, however, laryngeal lacerations and fractures require further therapeutic interventions. While some propose immediate surgical intervention, others suggest a three- to five-day waiting period prior to operative intervention. Study […]", "pred_label": "__label__POS", "pred_score_pos": 0.9515141248703003}
{"content": "Abstract\nBackground We conducted a meta-analysis to assess the efficacy of immune checkpoint inhibitors (ICIs) (PD-1/L1 and CTLA-4 inhibitors) in first and subsequent lines in East Asians and non-East Asians. Methods We searched PubMed-MEDLINE, Embase and Scopus, from inception to 20 Sep 2019, and reviewed major conferences’ abstracts, for randomised controlled trials of ICI in advanced-stage NSCLC (Stage IIIB or IV) without EGFR mutation that reported hazard ratios (HRs) stratified by geographical region including the region “Asia” or “East Asia”. The primary outcome measures were overall survival (OS) and progression-free survival (PFS). The pooled HR and its 95% confidence interval (CI) for OS and PFS in East Asians and non-East Asians were calculated using a random effect model and the difference compared using an interaction test. Results A total of 5,465 patients from 7 randomised controlled trials involving CTLA-4 and/or PD-1/L1 inhibitors were included, with 1,740 (32%) East Asians and 3,725 (68%) non-East Asians. ICI was associated with an improvement in OS and PFS for both East Asian (OS HR, 0.74; 95% CI, 0.65–0.85; PFS HR, 0.56; 95% CI, 0.40–0.79) and non-East Asian patients (OS HR, 0.78; 95% CI, 0.72–0.85; PFS HR, 0.69; 95% CI, 0.56–0.85), with no significant difference between the two groups (Pinteraction=0.55 for OS; Pinteraction=0.33 for PFS). Subgroup analyses showed a statistically significant superior PFS (but not OS) for East Asians than non-East Asians in trials that used immune checkpoint inhibitor in the first-line treatment (Pinteraction=0.02). No significant regional difference was found in further subgroups of pure ICI and combination of ICI with chemotherapy. Conclusions There is no significant difference in response to ICI between East Asians and non-East Asians with advanced stage NSCLC, and the statistically significant subgroup difference in PFS in the first line use of ICI may not be clinically significant.", "pred_label": "__label__POS", "pred_score_pos": 0.6887105107307434}
{"content": "Tax depreciation schedules are one of the most significant yet under-utilised tools available for property investors to maximise their returns. However, a large proportion of people still fail to realise the benefits of ordering a tax depreciation schedule. It is now estimated that through depreciation landlords could claim back between ten and forty per cent…\n30", "pred_label": "__label__POS", "pred_score_pos": 0.9999725818634033}
{"content": "Formal education and informal public engagement are both critical ways to raise awareness of the importance of antimicrobial resistance and ways to combat it.\nThe principles of infection control and antibiotic stewardship are a key element of UCL's prestigious MBBS undergraduate medical degree. UCL also runs a master's programme in Healthcare-associated Infection Control, in partnership with Public Health England and the Infectious Disease Society. The course has a strong distance learning component, and aims to provide highly practical guidance on effective infection control in healthcare settings.\nUCL School of Life and Medical Sciences also has a strong commitment to public outreach, and encourages researchers to participate in public engagement activities, including those related to antimicrobial resistance.", "pred_label": "__label__POS", "pred_score_pos": 0.972490668296814}
{"content": "Posted On July 08, 2019\nMortgage rates are still hovering around year-long lows, following dovish remarks by the Federal Open Market Committee at their June meeting. This week, the only significant housing report will be the Mortgage Bankers Association (MBA) weekly mortgage application survey. Other market-moving reports include consumer credit and the Labor Department’s Job Openings and Labor Turnover Survey (JOLTS).\nConsumer credit counts total outstanding consumer debt including revolving credit like monthly credit card bills and nonrevolving credit like student loans and auto loans. In April, consumer credit increased by $17.5 billion, the most in five months. Non-revolving credit increased by 4.2% and revolving credit increased by 7.9%, suggesting consumers are more actively spending.\nThe Job Openings and Labor Turnover Survey (JOLTS) tracks job openings, hiring, and voluntary quits. Job openings fell slightly to a level of 7.45 million. Hiring hit a record high in April, hitting 5.9 million.\nThe weekly mortgage application survey returned mixed results for the week ending 6/28. New purchase application submissions increased 1.0% and refinance application submissions decreased 1.0% for a composite decrease of 0.1%. Mortgage rates are likely to stay low for the rest of the year, triggering new purchase and refinance mortgage activity.\nStrong consumer spending and a strong labor market typically translate to economic growth. The housing market is also expecting a gainful second half of the year with lower mortgage rates and a slowdown in home price appreciation.", "pred_label": "__label__POS", "pred_score_pos": 0.722051739692688}
{"content": "Background: Individuals with genetic disorders and autism often have feeding difficulties that differ from typically developing children. In CHARGE syndrome (coloboma occular, heart problems, choanal atresia, retardation of growth, genitourinary anomalies, ear malformations), more than 90% need initial tube feeding and over 75% have cranial nerve dysfunction, contributing to weak swallow/sucking. These features lead to feeding difficulties that may not be accurately captured using current validated questionnaires. Objectives: To develop a user-friendly scale for parents and clinicians to assess feeding difficulties in individuals with CHARGE syndrome across their lifespan, as well as have the scale be validated in autism and other genetic syndromes in the future. Methods: The new feeding scale was adapted from the Pediatric Assessment Scale for Severe Feeding Problems (PASSFP), a validated scale that assesses feeding problems in typically developing children. Questions specific to CHARGE syndrome, other genetic syndromes, and autism were extracted from the current literature and reviewed by expert clinicians and feeding therapists. Ten parents piloted the new scale. It was then sent out, along with the PASSFP and general feeding history questions, to parents of individuals with CHARGE syndrome. A subset of parents completed the new scale again 2-4 weeks later to assess test-retest reliability. Results: One hundred parents participated from around the world (Canada, USA, UK, Australia, New Zealand, Europe). Individuals with CHARGE syndrome had an average age of 10.9 years (SD 8.3, range 1-33). Most common feeding difficulties were swallowing (25%), chewing (19%), and mouth over-stuffing (16%). The new scale had good construct validity, as there was a significant effect for an increased number of feeding difficulty risk factors having higher scale scores (p<0.001). Face validity of the new scale was found to be high, as scores significantly differed between individuals whose parents described their current feeding difficulties as very mild, mild, moderate, severe, and very severe (p<0.001). Test-retest reliability was high, with a significant correlation between the first and second scale completions (r=0.94, p<0.001). The new scale also had a high level of internal consistency (cronbach's alpha 0.91), indicating that each scale question performed well and did not need to be discarded. Lastly, there was significant convergent validity between the new scale and the PASSFP scale (r=-0.79, p<0.001), indicating that the new scale was assessing feeding difficulties well. Conclusion: The newly developed feeding scale for CHARGE syndrome is a reliable and valid tool, which can be used to provide both parents and clinicians a more accurate picture of oral feeding progress. The next steps are to validate this scale in individuals with autism and other genetic disorders.", "pred_label": "__label__POS", "pred_score_pos": 0.6617132425308228}
{"content": "On 14 July, the Belarusian Central Electoral Commission announced that Siarhei Cherachen, Andrei Dzmitryev, Hanna Kanapatskaya, Aliaksandr Lukashenka and Sviatlana Tsikhanouskaya were registered to stand in the Belarusian Presidential elections on 9 August. However, Viktar Babaryka was denied registration on the grounds that inconsistencies were allegedly found in his income and property declaration, and Valery Tsapkala was denied registration due to an alleged insufficient number of valid ballot access signatures and failure to disclose the ownership of Priorbank shares in the income and property declaration by his wife. Both candidates had reportedly collected more than 100,000 signatures, as prescribed by the national legislation.\nThe lack of transparency in the process of verification of the signatures supporting the presidential candidates, as already noted by the Organisation for Security and Cooperation in Europe’s Office for Democratic Institutions and Human Rights (OSCE/ODIHR) in 2010 and 2015, undermines confidence in the registration process. Moreover, the legal provisions for candidate registration pose disproportionate and unreasonable barriers to candidacy, contrary to OSCE commitments and other international standards.\nThe European Union regrets that the recommendations by OSCE/ODIHR to include substantial procedural and legal safeguards that enhance inclusiveness, integrity and transparency during all stages of the electoral process, in particular to introduce clear and reasonable criteria and mechanisms for candidate registration and signature verification have not been implemented. The EU expects Belarus to officially invite the OSCE/ODIHR without delay to observe the upcoming presidential elections.\nThe seemingly arbitrary exclusion of candidates limits the possibility for the Belarusian people to express their will and already undermines the overall integrity and democratic nature of the elections. By denying the registration of Viktar Babaryka and Valery Tsapkala the Belarusian authorities have failed to ensure a meaningful and competitive political contest.\nThe EU expects Belarus to respect the Belarusian citizens’ rights of freedom of expression and peaceful assembly in the weeks leading up to the elections.\nThe EU remains committed to strengthening its engagement with the Belarusian people and civil society. We support the independence and sovereignty of Belarus, but human rights and democracy will remain at the forefront of the EU's considerations when shaping its policy towards the country.", "pred_label": "__label__POS", "pred_score_pos": 0.8298332691192627}
{"content": "Headline CPI moderated to +2.4% y/y in August, from +2.7% a month ago. High base and softened growth in food inflation was the key reason for the slowdown. Food price rose +11.2% y/y, decelerated from +13.2% in July. This was mainly driven by the sharp moderation of pork inflation which eased to +52.6% from July’s +85.7%. Vegetable price picked up to +11.7% y/y, form +7.9% in July, however. Non-food inflation climbed slightly higher, by +0.1% y/y in August from a flat reading in July. Fuel price contracted -13.8% y/y, after a -15.5% decline in the prior month. Excluding food and energy, core inflation steadied at the subdued level of +0.5% y/y in August. PPI improved to -2% y/y, from July’s -2.4%. This signals that upstream prices stayed in deflation.\nEarlier this week, it was reported that China’s trade surplus narrowed to US$ 58.93B in August from US$ 62.33B a month ago. Yet, this came in better than consensus of US$ 50.5B. Exports accelerated to +9.5% y/y in August from +7.2% in July, beating consensus of +7.1%. Besides low base, exports were helped by strong shipment to China’s largest trading partner, the US, which expanded +20% y/y in August, accelerating from +12.5% a month ago. Exports to Japan slipped -0.8% y/y, improving from -2% in July. However, exports to ASEAN grew +12.9%, easing from +14% in July. Exports to EU and Japan contracted -6.5% and -0.8% during the month, respectively. Hopefully, exports would continue to recover in coming months as global economy continues to improve.\nImports contracted -2.1%, worsening from July’s -1.4%. Imports of major commodities remained weak. Copper imports expanded +67.2% y/y in August, decelerating form +72% a month ago. Iron ore imports contracted -4.9% y/y in August, following a gain of +10.6% in the previous month. Meanwhile, crude oil imports declined -24.6% y/y in August, after July’s -26.8% contraction. On agricultural products, China’s imports slowed especially in soybean and fruit. Country-wise, imports from EU, ASEAN, Africa and Latin America improved, while imports from US, Japan and Korea eased. It is likely that the slowdown of imports from Canada and Australia was driven by geopolitical tensions with these countries.", "pred_label": "__label__POS", "pred_score_pos": 0.9296760559082031}
{"content": "Beyond 2020 - Strategies and Costs for Transforming the European Energy System\nPosted: 3 Mar 2014 Last revised: 12 Mar 2015\nDate Written: February 27, 2014\nAbstract\nThe Energy Modeling Forum 28 (EMF28) study systematically explores the energy system transition required to meet the European goal of reducing greenhouse gas (GHG) emissions by 80% by 2050. The 80% scenario is compared to a reference case that aims to achieve a 40% GHG reduction target. The paper investigates mitigation strategies beyond 2020 and the interplay between different decarbonization options. The models present different technology pathways for the decarbonization of Europe, but a common finding across the scenarios and models is the prominent role of energy efficiency and renewable energy sources. In particular, wind power and bioenergy increase considerably beyond current deployment levels. Up to 2030, the transformation strategies are similar across all models and for both levels of emission reduction. However, mitigation becomes more challenging after 2040. With some exceptions, our analysis agrees with the main findings of the “Energy Roadmap 2050” presented by the European Commission.\nKeywords: European Decarbonisation, Mitigation Scenarios, Model Comparison, Climate Change, EU Energy Roadmap 2050 JEL Classification: Q2, Q4", "pred_label": "__label__POS", "pred_score_pos": 0.9939927458763123}
{"content": "These predictions from PulsePoint CEO Sloan Gaon might just be the insights you need to stay ahead of the curve.\nYou’ve had a tennis accident and suspect the worst: a broken leg. A telemedicine doctor-on-demand confirms your fears. You need to see a physician in person. From your phone, you nab an Uber Health ride (HIPAA-safe, affordable, and reliable) covered by your CVS/Aetna health plan. At a state-of-the-art medical mall, the wait for an x-ray is short. You barely have time to pull out your iPhone and find your secure MyChart health records, data that is owned by you, but protected by blockchain. Like clockwork, the radiologist’s report appears in the app, an orthopedist casts your leg, and you schedule both your follow-up and physical therapy appointments right then and there.\nThis might sound like science fiction, but it’s getting closer every day. Healthcare is on the cusp of a technology revolution. In fact, technology is primed to disrupt healthcare more profoundly than it has any other industry.\nToday’s healthcare system is terribly sick, with symptoms like fragmentation, prohibitive costs, bureaucratic red tape, and barriers to access. Tomorrow, technology will drive innovation, automation, transparency, and efficiency. Its effects will upend the industry, shrinking costs, improving outcomes, and rendering the current healthcare landscape unrecognizable.", "pred_label": "__label__POS", "pred_score_pos": 0.6730828285217285}
{"content": "This study examines black and Latino race relations within South Los Angeles, specifically Jefferson High School during and after the occurrence of a series of racial conflict during the 2004-2005 academic calendar. We analyze racial deprivation of public services, economic stability, and black and Latino concerns over policing and changing demographics within the historic context of the Watts Riot of 1965 and the Los Angeles Unrest of 1992. We argue that although the socioeconomic conditions within South LA provided the fuel for such violence, inequality of education is the leading factor in sparking race riots after racial group concerns over such conditions have been minimally challenged or ignored. In a case study of Jefferson High School, our interview results show that most students and parents do not consider race but gangs to be the fuel that started the media reported ?race riots.? Similarly, interview and participant observation of faculty and ?help? organizations point to the racialized gang violence spilling into the school that instigate racial conflict. We purport that because South LA has a history of economic decline and social unrest, this effects contemporary inter-group relation between blacks and Latinos at Jefferson High School. Furthermore, the absence or minimal participation of such stakeholders within intervention strategies alienates their concerns and leads to exclusive organized efforts in response to such conflict.", "pred_label": "__label__POS", "pred_score_pos": 0.6246775984764099}
{"content": "GALVESTON, Texas – City of Galveston property owners who sustained property damage during Tropical Storm Beta may be eligible for temporary tax relief, Galveston authorities announced Thursday.\nProperty owners are encouraged to complete an exemption application which is available online and submit it to the Galveston County Appraisal District.\nThe Texas Tax Code provides for a temporary exemption for property owners who are victims of natural disasters. This exemption is automatic for all governments adopting a tax rate on or after the governor’s disaster declaration. All others must adopt the exemption.\nGovernor Greg Abbott on September 21st proclaimed a state of disaster due to Tropical Storm Beta, including Galveston County.\nThe City of Galveston adopted its tax rate four days prior to the disaster proclamation on September 17, 2020. Therefore, Galveston City Council on Thursday voted unanimously to provide its residents with the ability to apply for this exemption.\nThe deadline for the application will be through January 2021, and you may access the application form here.\nHomeowners must apply for the temporary tax relief and must submit the application to the Galveston Central Appraisal District. The chief appraiser will rate the assessment based on the total damage to determine the percentage of tax relief the homeowner will receive.\nThe exemption will be applied as a prorated percentage for the portion of the year in which the owner was unable to enjoy their property due to the damage.\nPlease contact the Galveston Central Appraisal District at (409) 935-1980 or email gcad@galvestoncad.org with questions.", "pred_label": "__label__POS", "pred_score_pos": 0.5751534700393677}
{"content": "The Food and Drug Administration (FDA) is warning healthcare professionals to not use Treanda (bendamustine HCl solution; Teva) Injection 45mg/0.5mL or 180mg/2mL with closed system transfer devices (CSTD), adapters, and syringes containing polycarbonate or acrylonitrile-butadiene-styrene (ABS).\nAn ingredient found in Treanda Injection called N, N-dimethylacetamide (DMA), is not compatible with polycarbonate or ABS; these devices dissolve after contact with DMA. This can result in device failure and possible product contamination. Potential serious adverse events, including skin reactions in healthcare professionals preparing and administering the product, and the risk of small blood vessel blockage in patients, may also occur.\nThe FDA is requiring label changes reflecting safe preparation information for both the solution and powder formulations of Treanda. If using Treanda Injection (45mg/0.5mL or 180mg/2mL), the recommendations are as follows:\nIf a CSTD would be used with Treanda Injection, FDA advises healthcare professionals to verify with the CSTD manufacturer or Teva U.S. Medical Information (800-896-5855) that the CSTD is compatible with Treanda Injection prior to preparing the drug. FDA recommends healthcare professionals only use a polypropylene syringe with a metal needle and polypropylene hub to withdraw and transfer Treanda Injection. Polypropylene syringes are translucent in appearance. Treanda Injection should be inspected visually for particulate matter and discoloration prior to administration whenever solution and container permit. Treanda Injection must be withdrawn and transferred for dilution in a biosafety cabinet (BSC) or containment isolator and withdrawn and transferred using a polypropylene syringe with a metal needle and a polypropylene hub.\nContinue Reading\nIf using Treanda for Injection (25mg/vial or 100mg/vial), the lyophilized powder formulation, the recommendations are as follows:\nTreanda for Injection), must be reconstituted. If a CTSD or adapter is to be used as supplemental protection during preparation, only use Treanda for Injection and not the solution formulation. Do not mix or combine the solution and lyophilized powder formulations of Treanda.\nFor more information visit FDA.gov.", "pred_label": "__label__POS", "pred_score_pos": 0.8253378868103027}
{"content": "In April 2020, the\nHumanities for All team partnered with the Council of Independent Colleges (CIC) to conduct focus groups with students who had participated in publicly engaged projects funded by the CIC’s Humanities Research for the Public Good (HRPG) grants. We held five focus groups with 20 students from 15 institutions who generously shared their thoughts on what they learned and the skills they gained through publicly engaged humanities work. We present a summary of the focus group responses here, while individual posts written by four focus group participants are on the Humanities for All blog:\nDuring National Arts and Humanities Month,\nHumanities for All has been exploring how higher ed-based humanists are using the tools of public humanities and partnership to promote social and racial justice. In recent decades, many American colleges and universities have begun uncovering their historic support and involvement with the institution of slavery (and the ongoing denial of these linkages) as a way of mending a broken sense of trust between students, colleges, and the surrounding community.\nOver the past 18 months, NHA has worked with 14 project directors of NEH-funded summer seminars, institutes, and landmarks workshops. These residential, thematic professional development programs help K-12 educators access engaging and up-to-date humanities scholarship and immerse them in the histories and cultures of American regions. Together, we have surveyed participants in these programs, documenting their impact on teachers’ classroom practice. In addition to pre- and post-program surveys, we followed up with teachers a year later, asking about how they had incorporated their work in the programs into their praxis.\nEach October, we celebrate National Arts and Humanities Month by calling attention to the many ways humanities research, teaching, and programs serve students and communities across the country.\nBy Emily McDonald and Younger Oliver\nAdvocacy on behalf of our cultural institutions is as crucial now as ever. The COVID-19 crisis has cast a shadow of deep uncertainty on all areas of American life, and how far these social and economic impacts may reach is still very much unknown. Over the past six months, we have been working to better understand the challenges humanities organizations are facing and how they are serving their communities in the face of crisis. We’ve found our peers are not only providing informative programming, but also extending their missions to serve their communities in creative ways. To fully capture the impact of this work, we have been partnering with humanities organizations across the country, leveraging the data collection resources we’ve developed at NHA, to highlight how humanities organizations serve as anchors in their communities during times of crisis.\nThis summer, we launched the\nHumanities for All blog to showcase publicly engaged humanities initiatives in the words of the faculty, staff, students, and community partners directly involved in the projects. Our September 8 post by Lillian Wilson focuses on the Wayne State Humanities Clinic, an innovative graduate internship program at Wayne State University in Detroit, Michigan. Twenty-three interns from the humanities and humanistic social sciences were matched with 25 non-profits and businesses that serve Detroit communities. In some cases, an interdisciplinary group or pair of interns worked with a single community partner.\nWe recently hosted a two-part webinar entitled\nMaking the Case for Studying the Humanities in a Time of Crisis. For more than a year now, we’ve been researching the field of undergraduate humanities recruitment, identifying compelling initiatives, effective strategies, and leaders in the field. We gathered six of those leaders—three deans followed by three humanities center directors—to discuss how the pandemic, severely strained budgets, and the national reckoning with racial injustice are changing the context in which they work to attract more students to the humanities.\nIn August of 2019, NHA and Routledge, Taylor & Francis launched\nPublishing and the Publicly Engaged Humanities, a free-access collection of humanities articles and book chapters that feature public engagement. The collection, drawn from across the Taylor & Francis books and journals programs, illustrates a range of ways that publicly engaged scholarship can lead to—and enhance—publication. The initial collection included 10 publications, which we augmented twice to include new articles and book chapters.", "pred_label": "__label__POS", "pred_score_pos": 0.7123529314994812}
{"content": "Today's entrepreneurs are continually disrupting traditional industries, coming up with innovative products and services that fulfil the changing needs of modern consumers. However, despite the ingenuity behind these developments, business owners often struggle to market their offerings to ad-fatigued target customers effectively. Luckily, you can take inspiration from some of the world's top brands and their outstanding marketing strategies.\nAmong these pioneers is the video streaming giant, Netflix. Founded in 1997 as an online video rental service, the brand transitioned to a subscription-based business model in 1999, before making its most recent (and notable) adjustment to online streaming in 2007. During this time, it has had to adjust and tweak its marketing plans repeatedly.\nRather than battling the challenges that its shifting target audience poses, though, Netflix has capitalised on them through its unique promotional approach. As a result of its marketing success, the company now boasts 183m paid memberships in over 190 countries, making it the world's leading streaming entertainment service. Its value has soared during the current year, reaching an astronomical $196m as of April 2020 and even surpassing entertainment behemoth Disney.\nNetflix's Marketing Approach\nThe superbrand utilises an impressive marketing budget of around $2.65bn (as of 2019) to execute its promotional activities, adopting a variety of online and offline methods to attract new and existing audiences. At the heart of this is the company's original content, which includes hundreds of shows and movies available exclusively on Netflix's platform.\nIn a broader context, its digital marketing strategy focuses on building strong relationships between the brand and its viewers, cultivating a unique identity through humorous messages and references to popular TV series and films available on Netflix. This familiarity adds authenticity to the brand's voice and makes it easier to engage with as a result. In this way, Netflix outshines its competitors – including Amazon Prime Video, Google and Hulu – that typically take a more formal approach to their marketing communications.\nThe company's offline marketing, meanwhile, promotes Netflix Originals to new audiences using well-placed outdoor banners, and even captivating, unexpected outdoor ambient marketing.\nCustomer Profile\nNetflix's subscribers are equally male and female, falling within a wide age range of 18 to 54. Viewers span all levels of education, with users on opposite ends of this spectrum often indulging in the same content. Customers are also on even footing with regards to household incomes, though there is a slight increase in users of higher income brackets, as is typical for a subscription business. This large demographic is testament to the company's success in offering an impressive variety of content that appeals to large volumes of users.\nCustomers tend to be loyal to the brand, too, with the majority of surveyed users in the US claiming that they would keep their Netflix subscription even if the monthly price increased. Indeed, most say that they would still use the service if adverts were added, regardless of whether the monthly fee would be reduced or stay the same.\nThe brand captures both quantitative and qualitative data of its users' behaviour through its desktop site and mobile app to support its extensive market research efforts. Analysis of this information is then used to adjust Netflix's advertising strategy to better target ideal customers. The company mostly leverages primary research to this end, with its in-house research team regularly exploring potential improvements in its studio production, marketing, content delivery, application domain and more.\nMarketing Mix\nThe success of Netflix's strategy lies in its ability to foster strong bonds with customers, and efficiently recruit new users. This is achieved through omnichannel delivery of digital communication, clever partnerships with major companies, compelling original content, and attention-grabbing outdoor advertising, as detailed below:\nAd-Free Digital Delivery\nRather than fighting against the current of modern viewers' ad fatigue, Netflix takes advantage of this. The streaming service effectively attracts more users to its platform by offering its content without any adverts, regardless of consumption time. This has become a major part of its clear value proposition; in the brand's own words, \"you can watch as much as you want, whenever you want without a single commercial – all for one low monthly price.\"\nIn addition, the service is accessible across all digital devices, making it even easier for mobile users to consume content in whichever way they prefer. This is also an example of the company's effective evaluation and use of its market research conclusions.\nSocial Media Marketing\nNetflix makes use of the popular social media channels that its target customers frequently use, aiming to inspire engagement from online audiences. Primary platforms include Instagram, Snapchat, Facebook, TikTok, YouTube, and Twitter.\nIndeed, the company crafts a unique personality online, posting entertaining and amusing informal imagery and text, such as memes and throwbacks, that sharply contrast the more stiff, pre-prepared digital marketing content shared by its competitors. The content and format of Netflix's posts are also tailored to the platforms that they are shared on, taking advantage of the focus and approach of each channel, while also ensuring omnichannel delivery of its campaigns.\nNetflix heavily interacts with followers, too, as well as listens closely to their comments and feedback to further curate the brand's digital persona.\nDigital Segmentation\nUnderstanding that segmentation is important, the brand maintains separate profiles on the same social media sites for different content topics. In fact, Netflix has individual accounts for some of its most popular original TV shows, as well as entire movie and show genres. This allows followers to tap into the posts that are most relevant for them, and personalise their online experience with the service.\nIn addition to this targeting, the brand also adopts geographic segmentation, with separate accounts for different countries and regions. These profiles feature local languages and utilise regional user preferences for better results.\nPartnerships\nNetflix invests in collaborations with digital partners to bring its service offering to the attention of new customers within broadening territories.\nOne such collaboration was its 2017 augmented reality experience with Snapchat, a campaign that visually immersed the social media channel's users in the set of Netflix Originals show\nStranger Things. This was used to promote the series' new season ahead of its release. The hype around this partnership contributed to new awareness of the programme and brought higher viewership as a result.\nIts most recent partnership is with Korean tech giant Samsung. Their 2020 agreement sees Netflix become the brand's mobile entertainment partner, in a bid to beat upcoming streaming competitors. Samsung Galaxy smartphone users will have exclusive access to additional content from Netflix Originals shows and movies, such as behind the scenes footage, while the partnership will also allow for further integration of the entertainment provider with Samsung devices.\nOriginal Content\nA major key to Netflix's business success and marketing excellence is its creation of captivating, unique movies and TV shows, such as\nHouse of Cards, Narcos, Orange is the New Black, and The Crown. The brand takes this endeavour seriously, investing an enormous $17bn in 2020 to develop and produce this content.\nAvailable exclusively via the streaming platform, it is among Netflix's major competitive advantages and growth drivers. Not only does this approach retain existing customers, as they cannot find this unique content elsewhere; it also effectively attracts new subscribers who want to explore the hyped programmes in question.\nOutdoor Advertising\nIn addition to its high-cost, highly targeted digital marketing activities, Netflix also invests in valuable offline advertising that captures the attention of broad audiences. This marketing method is most suitable for attracting new users to the platform and can lead to satisfactory results when ads are placed in areas of particularly high traffic.\nThe entertainment giant utilises billboard and bus stop ads to raise general brand awareness, as well as promote specific content available for streaming.\nAmbient Marketing\nNetflix's outdoor marketing occasionally crosses the border into ambient marketing, a popular form of guerrilla marketing that draws attention by placing unexpected promotional material in areas that are not typically used for advertising. Consumed by vast audiences, this method ensures greater marketing message retention among viewers, due to its startling nature.\nOnce again, these efforts usually focus on promoting Netflix Originals content. For example, in 2015 the brand created a street art visual display along the side of a building in Paris – a high area of Netflix customers – to build anticipation for the third season of\nOrange is the New Black. In addition to scrawling the show's title and Netflix's branding on the façade, the design incorporated what appeared to be 12 physical prison cells (reflecting the show's subject matter). In a live stunt, supposed female inmates donned in orange jumpsuits were led to these cells and posed as part of the display, clearly visible to curious Parisian onlookers below. Style\nThe streaming service habitually reinvests a significant portion of its global revenues into marketing, prioritising the creation of high-quality original content, while spending lesser amounts to ensure the content's promotion to appropriate audiences.\nNetflix is proudly self-sufficient, too, conducting market research and executing campaigns through its specialised in-house teams and seldomly seeking the support of external agencies. As a result, it has become well-known for this approach, which is unique among its main competitors.\nThe company offers budding businesses a prime example of how to find success in perfecting a distinctive identity, making their value proposition explicitly clear to consumers and sticking to their most suited methods of marketing rather than mimicking their competitors' approach.\nKey Campaign\nThe entertainment giant once again showcased its marketing mastery during a particularly successful 2016 campaign, promoting its original series\nHouse of Cards. The campaign sparked interest, discussion, and engagement from online audiences, ultimately attracting viewers and brand awareness.\nThe campaign's timing was exquisite. Featuring the show's political protagonist Frank Underwood and his fictional bid for US president within the series, it was released to audiences during the lead up to the real-life 2016 US election. This allowed for cross-over discussions between the show's storyline and reality, taking advantage of significant digital traffic around political themes and redirecting a portion of this attention to the series.\nPromotional material included a minute-long video shared on YouTube that showed Underwood relaying his election promises, blended with snapshots of the show's action-packed scenes. The campaign also saw the creation of a website (FU2016.com) dedicated to the political bid, complete with media assets for fan consumption, as well as a wide-spread social media campaign championing the hashtag\n#FU2016. The simple visuals created were effective in drawing reactions from viewers, as they matched the unique imagery of the show, while also uncannily mimicking the political banners distributed by real-life candidates Donald Trump and Hillary Clinton.\nAlthough Netflix does not publicly release results of its marketing efforts, the amusing, controversial campaign certainly attracted significant attention online and garnered engagement from existing fans of the show, as well as new viewers, celebrities and influential figures. Around 15,000 posts were shared on Instagram using the hashtag #FU2016, with countless tweets, retweets and other engagements received on Twitter. The campaign won the Integrated Grand Prix at the 2016 Cannes Lions International Festival of Creativity and was a Campaign of the Year Finalist at Ad Age's 2016 New Creativity Awards.\n---\nOverall, Netflix expertly executes online and offline marketing, utilising in-depth market research to hone its approach for maximum success. The brand creates a strong, identifiable voice and identity through its promotional communications, enhancing its authenticity, and contributing to the development of strong relationships between the brand and its users.\nSmall businesses can learn from the streaming leader and build a promotion strategy around a central competitive advantage, as Netflix does with its original content. Entrepreneurs can also adopt the brand's ingenious sense of creativity and find success in adopting a varied marketing mix to support its main objectives.\nWas this article helpful? Let us know your thoughts on Netflix's marketing strategy in the comment section below!", "pred_label": "__label__POS", "pred_score_pos": 0.6780848503112793}
{"content": "NDI-USA has just published Monitoring and Mitigating Electoral Violence through Nonpartisan Citizen Election Observation.\nThis is a guide book informed by lessons learnt around election monitoring shared by international election observers who attended a workshop held in Bangkok in 2013. The Executive Director of CPA, Dr. Paikiasothy Saravanamuttu, was also part of this workshop.\nNDI-USA visited CMEV to gather details for this guide, and have highlighted CMEV’s experience in several places throughout the guide, including on page 19, 30 and 52, as well as in the main Sri Lanka case study on page 81.\nThis is the first guide specifically focused on outlining and systematizing strategies and methods for citizen election observers to monitor and mitigate electoral violence. The guide outlines an overall approach for designing electoral violence monitoring and mitigation strategies, and then takes a practical look at four key areas in which citizen observers can contribute to mitigating electoral violence: (1) long-term election observation; (2) traditional and social media monitoring, reporting on hate speech, and contributing to media accountability; (3) crowdsourcing and visualizing electoral violence-related data; and (4) grassroots electoral violence mitigation and mediation efforts.", "pred_label": "__label__POS", "pred_score_pos": 0.961280107498169}
{"content": "The ESG program is a component of the state's Continuum of Care system designed to alleviate homelessness in Brownsville. ESG programs enable homeless individuals and families to move toward independent living by providing emergency housing, supportive services, and housing assistance. ESG funds are provided by the U.S. Department of Housing and Urban Development (HUD) on an annual basis and administered by the City of Brownsville.\nGoals\nThe general goals of this funding are consistent with those established by HUD and are intended to benefit people at risk of homelessness or homeless.\nExpand economic opportunities\nProvide decent housing\nProvide a suitable living environment\nEligible Activities\nEligible activities funded under ESG include the following:\nEngage homeless individuals and families living on the street\nImprove the number and quality of emergency shelters for homeless individuals and families\nHelp operate these shelters\nProvide essential services to shelter residents\nRapidly re-house homeless individuals and families\nPrevent families and individuals from becoming homeless", "pred_label": "__label__POS", "pred_score_pos": 0.9717608094215393}
{"content": "The educational system is broken – and unfair. For decades, learning was limited by geographic location and finding the means to continue with higher education. Online learning and massive open online courses (MOOCs) were being promoted to address the inequities in education while extending its reach across all geographies. However, the online model simply paved over the older methods with technology; in the end, they perhaps even made things worse by pushing course materials to students without an effective way to track their learning outcomes and their degree of attention.", "pred_label": "__label__POS", "pred_score_pos": 0.7975332736968994}
{"content": "Abstract\nProgression of malignant potential in ovarian cancer was investigated by comparing recurrent tumor with their primary tumor counterparts in terms of p53 and CD44 variant 6 (CD44v6) expression. Forty-three paired primary and recurrent tumors were immunohistochemically evaluated for expression of p53 and CD44v6. A paired analysis revealed that p53 and CD44v6 expression were significantly greater in recurrent tumors than those in the primary counterparts with statistical significance, respectively (P=0.0055 and 0.0071; Wilcoxon signed-rank test). No relationship between these two proteins was found. These results suggested that recurrent ovarian cancer may possibly express a stronger malignant potential in comparison to the primary tumor.\nAll Science Journal Classification (ASJC) codes Oncology Cancer Research", "pred_label": "__label__POS", "pred_score_pos": 0.9936798810958862}
{"content": "Scholarly journals report on research conducted by scholars, and professionals in the field, and provide in-depth articles that cover specific issues or research questions. Peer-reviewed articles are evaluated by a group of experts, or peers, based on their originality, currency, and validity. Journal article databases contain many types of articles, including: book reviews, editorials, newspaper and magazine articles, trade journal articles and scholarly (academic or peer-reviewed) articles. Criteria for evaluating academic or scholarly articles include:\nDepending on the assignment, using web or online resources may not be appropriate. Check with your professor before including these sources in your work.", "pred_label": "__label__POS", "pred_score_pos": 0.9711031317710876}
{"content": "Sexual discrimination, harassment and abuse of power have plagued the wine industry for too long. It is the responsibility of us all to acknowledge this, to empower people to speak up, and to support our colleagues in sending a clear message that this behavior is totally unacceptable and will not be tolerated. Here are three actions to build on the momentum of change.", "pred_label": "__label__POS", "pred_score_pos": 0.9167940616607666}
{"content": "Abstract\nBody dissatisfaction is particularly prevalent during adolescence and has recently been linked to stress in females and males. However, prospective studies are needed to better understand the relationship between stress and body dissatisfaction. The present study investigates the direction of this association and the mediating role of self-esteem and body image importance. A sample of 298 adolescent females and males in Grades 7 to 10 (ages 12 to 17 years) were surveyed at two time points over a one-year period. Hierarchical regression analyses revealed that stress significantly predicted body dissatisfaction one year later. Furthermore, a multiple mediation analysis controlling for gender revealed a significant indirect effect in both cross-sectional and longitudinal models, indicating that stress predicts reductions in self-esteem and increases in body importance, which in turn predict body dissatisfaction. These findings suggest that stress, self-esteem, and body importance should be included in programmes aimed at improving body dissatisfaction", "pred_label": "__label__POS", "pred_score_pos": 0.9997944235801697}
{"content": "In order to stay ahead of the competition, companies need to maintain peak productivity. When positions sit vacant for extended periods, keeping up with demand or spurring growth becomes increasingly challenging. This is especially true of the unfilled role represents a skill that isn’t present in the organization’s current workforce, allowing a skill gap to hinder the capabilities of the team overall.\nFinding methods to reduce your time-to-fill can be critical when you want to remain competitive. As a leading managed services provider (MSP), smRTpass offers comprehensive services designed to streamline hiring. With the Talent Curation program from smRTpass, you can lower your time-to-fill dramatically. Here’s a look at how Talent Curation from smRTpass can help.\nFocused Talent Pools\nThe smRTpass delivery teams curate talent pools for partner companies that are designed to align with your talent demand, workforce strategy, and larger organizational goals. Your needs are fully assessed to determine which approaches will meet your needs in the most effective way possible.\nIn addition, the Talent Curation program is designed to be agile. Should your needs or priorities change, smRTpass will curate new focused talent pools around those parameters, giving you access to the right kinds of candidates at the proper time.\nMultichannel Sourcing\nTalent Curation from smRTpass embraces a multichannel sourcing approach. The focused talent pools consist of candidates from a wide range of sources, including some that many companies accidentally neglect.\nInternal sourcing channels – including applicant tracking systems, vendor management systems, career portal databases, and more – are explored to identify candidates that are vetted and known quantities or already part of your recruitment landscape. By assessing data on known talent, such as past employees or contingent workers, past interviewees, and referrals that were not initially pursued, you can reduce your time-to-fill substantially. This process reduces the need for external recruitment, an approach that can both be costly and time-consuming.\nAdditionally, if existing or past employees could excel in the role, you can also expedite the hiring process. You may already have certain information on-file, allowing you to reactive a previous employee instead of adding a new professional to your system.\nEssentially, Talent Curation from smRTpass allows you to harness the power of your existing data and use it as a recruitment source for known talent. This can significantly reduce the need for external sourcing, allowing you to expedite your hiring process and reduce time-to-fill. Plus, the data is analyzed to find quality matches. As a result, you can access a curated talent pool based on your highest priority needs, ensuring a top-quality fit in the shortest time possible.\nUltimately, Talent Curation from smRTpass can help you fill vacant positions quickly and efficiently, ensuring your time-to-hire is reduced, and your company can reach full productivity faster than ever before.\nLearn More About the Power of Talent Curation\nIf you would like to know more about the power of Talent Curation, the team at smRTpass wants to hear from you. Contact us or download our guide, Harnessing Your Current Talent Ecosystem, to learn more about our services and see how Talent Curation from smRTpass can benefit you.", "pred_label": "__label__POS", "pred_score_pos": 0.9229066967964172}
{"content": "From back-of-house to center-stage, the kitchen has evolved from functionalism to sensationalism. Responding to cultural preferences and technological changes, the modern kitchen embraces an open floor plan allowing space for multiple cooks and activities and ample storage for utensils and appliances. The kitchen space is dynamic and will continue to adapt to cultural and technological changes over time, but the psychology of the kitchen will remain constant: the kitchen will always provide a place where heart, head, and stomach meet, a place where social intimacy mixes with the food preparation creating laughter, stories, and memories.\nRemodeling a kitchen, considered the most important room in the home, can be challenging. From cabinetry to countertop material, from appliance placement to lighting choices, designing and building a kitchen presents a myriad of decisions. Whether you are a traditionalist or minimalist, Gilday’s architects and kitchen designers can design a kitchen to reflect your lifestyle and personal tastes and embody it in supreme craftsmanship. We can’t predict the aesthetics of future kitchens, but we can guarantee the craftsmanship and integrity of our design, process, and construction.", "pred_label": "__label__POS", "pred_score_pos": 0.8087642788887024}
{"content": "Since 1988, December 1st has been observed as World AIDS Day. The World Health Organization designated this day to ensure renewed and ongoing attention to the threat posed by HIV/AIDS. It is estimated by Centers for Disease and Control (CDC) that over 1 million people in the United States are currently living with HIV.\nHemophilia Federation of America (HFA) observes and acknowledges this day in honor of our community members who contracted HIV and hepatitis C after injecting contaminated antihemophilic clotting factor into their bodies prior to 1985. Approximately ten thousand people with hemophilia contracted HIV (and hepatitis C) during this time, and no less than eight thousand have died.\nIn honor of our community members who are deceased and those who still struggle with co-morbidities contracted from contaminated products, we offer our gratitude for the heroic diligence and sacrifice in ensuring a safe blood supply for all.\nIn 2013, HFA hosted a webinar to honor World AIDS Day.聽 To view the recorded webinar, click here.聽 Also available for download are the slides and handout.\n聽Click Here for Webinar Slides:\n聽Click Here for Webinar Handout:", "pred_label": "__label__POS", "pred_score_pos": 0.6114460229873657}
{"content": "Appropriate company for mice\nEnsure your mice have appropriate company\nMice need:\nHousing in single-sex, stable, compatible, harmonious groups:\n-Ask breeders to pre-group before weaning, ensuring the group comprises of mice that know each other, ideally siblings.\n- Keep the group the same; don¿t add/remove individuals. Upsetting the group¿s complex organisation by adding/removing even one individual can cause intense, stressful conflict which can affect the welfare of all mice.\n- Ensure males can¿t smell females, as this can increase aggression between male cage mates.\nHousing with other mice ¿ they¿re gregarious and social. Never house them alone unless it¿s under specific veterinary recommendations. They find social isolation and/or individual housing incredibly stressful. If it¿s required, ensure they can see/hear/smell other mice of their own gender, and provide them with additional environmental resources to meet their needs. Consideration. Take care with group size/composition, and husbandry, when housing male mice in groups and ensure minimum disturbance. They can be aggressive to other mice they aren¿t familiar with. Mice form a complex social organisation within the group. How each individual fits within this social group can depend on age/gender/position/reproductive condition. Monitoring immediately after grouping and when they¿re placed back in the cage after cleaning, to avoid aggression. Checking regularly to ensure aggression isn¿t becoming a problem. Positive interactions with you. Gently habituate them to you; this reduces the stress associated with handling. Mice are a prey species; if not properly habituated to human interaction can find handling very stressful. Housing away from other rodent species. Ensure wild rodents can¿t enter the area where you house mice. They can also find the presence/scent of other animals in the home stressful. You to wash your hands and cage equipment properly before handling different species, and handling mice from different cages. Other rodent species don¿t make suitable companions for mice; they carry diseases which can be transmitted to mice and vice versa. Such diseases affect health and can be fatal. Themselves, and their home-cage, to be kept away from other animals within the home.", "pred_label": "__label__POS", "pred_score_pos": 0.5733692646026611}
{"content": "President Ibrahim Mohamed Solih, on Sunday, announced the establishment if the Institute of Chartered Accountants of the Maldives (ICAM), as mandated by the Maldives Chartered Accountants Act.\nAccording to a directive issued by the President's Office, ICAM was officially formed on September 8, coinciding with the date President Solih ratified the bill.\nICAM's mandate will include formulating standards for auditing and accounting in the private sector, regulating and monitoring the work of private sector accountants and auditors, setting valuation guidelines and providing accounting related assistance to the public sector as well as technical services such as certification, education and training.\nOver the course of the following three months, ICAM will issue new audit licenses, while those previously granted will be nullified after six months.\nThe accounting profession was previously regulated under the mandate of the Auditor General's Office, including the issuance of audit licenses since 2014.\nAs a measure to support the professional development of locals in the field, ICAM will also conduct training programmes, establish a code of ethics and accredit accountancy qualifications offered by colleges or universities to improve graduates' job prospects.\nAs per the AG Office, demand for the services of chartered accountants in Maldives had surged rapidly in response to sudden changes in economic activity, resulting in businesses hiring foreign workers. As a result, the majority of chartered accountants currently working in the country are still foreign nationals, despite a greater number of Maldivians now possessing qualifications in the field.\nSpeaking to The Edition, Auditor General Hassan Ziyath previously stated, \"We would like to extend opportunities for Maldivians\", highlighting ICAM's role in increasing local participation within the workforce.\nThe Auditor General's Office has long worked to establish an independent legal body such as ICAM to regulate auditing and accounting in Maldives.\nAs per the Maldives Chartered Accountants Act, ICAM will initially be led by a transitional council consisting of the Auditor General and eight additional members appointed to develop bylaws and standard operating procedures over four years. A key aim for the transitional period is seeking formal recognition from the International Federation of Accountants (IFAC).\nFollowing the transition period, the institute will be headed by an elected nine-member council consisting of a president, vice president and four members from ICAM, as well as the Auditor General, Commissioner General of Taxation and State Financial Controller.", "pred_label": "__label__POS", "pred_score_pos": 0.9872056841850281}
{"content": "At My Local Solicitor, we understand that many professional lawyers are no longer satisfied with what can often be a toxic and pressured working environment that can be detrimental to both their mental wellbeing and family life. Often working under overwhelming caseloads while serving increasingly demanding clients – with only a capped salary in return – entrepreneurial solicitors are seeking a more modern approach to their role.\nWe are now offering consulting solicitors an alternative to the traditional approach to practising law, while providing the same level of support and protection typically received at an established firm.\nAn agile way of working\nWe equip our self-employed consultants with the tools and room to be the architects of their own career path. We believe that unrealistic targets and long hours that keep solicitors from progressing are not beneficial to either them or the clients they serve.\nInstead, we empower the solicitors with the freedom to fix their own targets and select when, where and how they work, to suit their individual needs. We know that self-motivated solicitors have the skills, experience and drive to manage their own workloads, providing appropriate council for clients around their daily lives.\nWe firmly believe consultants with an improved work-life balance will always be more productive and effective in their role.\nFreedom with support\nWhile working remotely and flexibly can be more convenient, at My Local Solicitor we understand that legal professionals can benefit from strong support that offers advice, security, and resources.\nFrom setting their own pricing to selecting the hours they work, our consulting solicitors are afforded a flexible way of working while benefiting from expert advice, full indemnity insurance and secretarial services when required.\nNot to mention, we also believe our solicitors should have the freedom to retire how and when they want to, and they will receive our full support to do so.\nGet in touch today to become a part of our new and flexible approach to practising law.", "pred_label": "__label__POS", "pred_score_pos": 0.6975181698799133}
{"content": "I've developed an empirically-based approach to distinguishing perception from thought and have used this approach to argue that we perceive at least some high-level features. For instance, we sometimes literally perceive the intentions of others.\nI've also argued that beliefs are necessarily rationally revisable in a certain way. Mental states which lack this capacity aren't beliefs, though they might be some other sort of thought, such as a supposition or a pretense.\nIn new work, I argue that epistemological solipsism is both more resilient and more theoretically important than we might have thought.\nPronouns: she/her", "pred_label": "__label__POS", "pred_score_pos": 0.9999448657035828}
{"content": "Background: The aim of the current study is to report on a new form of treatment for cellulite based on a novel physiological hypothesis. Methods: A novel treatment for cellulite was evaluated in 14 patients aged 19-36 (mean 27.5) years. The only inclusion criterion was clinically diagnosed cellulite, and the exclusion criteria were history of edema, obesity, or any other disease diagnosed during the physical examination. Perimetry was performed at the gluteal fold, at 5 cm and 10 cm below the gluteal fold for both legs, and 5 cm and 10 cm below the navel. Additionally, standard photographs were taken and a questionnaire of satisfaction was applied. The patients were submitted to a treatment regimen of 1.5 hours per day adapted for the treatment of cellulite, consisting of manual and mechanical lymph drainage and cervical stimulation using the Godoy and Godoy technique. After 10 sessions over two weeks, the patients were evaluated again. Results: Reductions were identified at both points below the navel, the points on the thighs, and at the gluteal fold (P < 0.0001). Conclusion: This technique of lymphatic system stimulation is efficacious in the treatment of cellulite. Keywords: cellulite; physiopathology; treatment.", "pred_label": "__label__POS", "pred_score_pos": 0.7217033505439758}
{"content": "Venous Reflux Exam Are there significant advantages of a venous reflux exam when compared to other similar procedures?\nThe ultrasound techniques used are non-invasive. This is not the case with other diagnostic tools such as venography and arteriography.\nHow long do the results take?\nAt the AVC the tests are done, you may receive the results right away. Other clinics may take a few days. Many dedicated vein specialist have the equipment for a venous reflux exam right in their own office. If you have to go offsite for the tests, your healthcare provider will likely receive your results within a few days.\nWill my insurance cover the cost of a venous reflux exam?\nSince venous reflux exams are typically ordered by your physician to confirm a clinical suspicion or diagnose a medical condition, medical insurance companies usually cover this exam. You may still be responsible for copays or deductibles.\nAre there any risks associated with venous reflux exams?\nThere are no known complications or risks connected with venous reflux exams. It is a simple, non-invasive procedure that takes 30 minutes to an hour. Some people have reported feeling dizzy or lightheaded during the standing portion of the exam. This can be easily remedied by sitting down.\nWhat is the cost of a venous reflux exam?\nA venous reflux examination’s cost can vary based on where the test is performed on the body. Also varies with your provider’s fees, health coverage and whether the test is performed at an imaging center or in your physician’s office. Check with your healthcare provider for the specific on cost and coverage.\nThese “false negatives” can be dangerous. They may be falsely interpreted as normal but in reality we have no way of knowing since the test was not administered properly. If your technician does not test you while standing, ask why, and then seek a second opinion.", "pred_label": "__label__POS", "pred_score_pos": 0.5863984823226929}
{"content": "Dental Education PGCert\nBecome a better healthcare educator, whether you’re new to teaching or wanting to further your skills and knowledge in your educational role.\nMay 2021 24 months max Distance Learning Online\nThis specialist certificate in dental education is designed by dentists for those teaching in a dental context. It will help you analyse everyday teaching and learning opportunities, and will enhance your knowledge and skills of methods of teaching and assessment.\nMedical education is at the core of healthcare provision the world over. Ensuring the future workforce is prepared to meet the challenges of modern healthcare means we need experts in medical education to help shape practice.\nAt the Centre for Medical Education, founded over 40 years ago by Professor Ronald Harden, we enable medical educators to reach their goals, and ensure they're prepared to train medical professionals of the future, including dentists.\nOur wide-ranging curriculum fits around you and your working life, whether you're new to teaching and training, or wish to advance existing skills and knowledge.\nYou'll start with two core modules - Teaching & Learning in Medical Education and Principles of Assessment in Medical Education. These will give you a strong overview of the core concepts of medical education.\nYou'll then complete a specialist mod`ule that will help you critically evaluate teaching within a dental care setting while developing, delivering and reflecting on your own teaching and assessment of students.\nFollowing this certificate, you could progress on to our PGDip or Masters courses to further your learning.\nContact our applicant enquiry team", "pred_label": "__label__POS", "pred_score_pos": 0.5675351619720459}
{"content": "ACR: Children at risk for uveitis should continue ophthalmology care despite COVID-19\nChildren with rheumatic disease who are at high risk for chronic uveitis, or have a history of uveitis, should continue to receive routine ophthalmologic care, according to COVID-19 clinical guidance from the American College of Rheumatology.\nThe ACR announced the “COVID-19 Clinical Guidance for Pediatric Patients with Rheumatic Disease” on Thursday, alongside another set of guidance for pediatric patients with multisystem inflammatory syndrome associated with COVID-19. Both documents are pending journal peer review.\n“COVID-19 has had a profound effect on so many lives and has contributed to at least 400,000 deaths worldwide,”\nJay Mehta, MD, MS, of the Children’s Hospital of Philadelphia, who oversaw the task force that drafted the guidelines, told Healio Rheumatology. “Although children have not been as affected as adults during this crisis, there is still concern from the patients, their families and their pediatric rheumatology providers about the potential impact the virus may have due to underlying rheumatic disease, and the medications they are taking.”\n“Fortunately, the data suggest that children with a rheumatic disease on immunosuppressants are not getting sicker than other children without a rheumatic disease,” he added. “There are also questions about whether the children can attend summer camp and return to school in the fall. The Pediatric Rheumatic Disease Clinical Guidance document aims to help providers answer some of these questions for patients and their families.”\nJay Mehta\nTo provide clinical guidance to rheumatologists who treat pediatric patients against the background of the ongoing COVID-19 pandemic, Mehta and colleagues established the North American Pediatric Rheumatology Clinical Guidance Task Force in May. According to ACR, this task force included seven pediatric rheumatologists, two pediatric infectious disease physicians, one adult rheumatologist and one pediatric nurse practitioner. First, members drafted clinical questions based on a review of commonly found queries from patients, families, and rheumatology providers of children with rheumatic diseases during the COVID-19 pandemic.\nThe task force then developed an evidence report based on a comprehensive review of the literature. Members voted anonymously on initial questions and subsequent statements in three rounds using a modified Delphi approach. The panel gathered in three webinars to further discuss these statements and reach consensus. Final voting was completed using a 9-point numeric scoring system with predefined levels of agreement and consensus. To be approved as a guidance statement, median votes were required to fall into the highest tertile for agreement with “moderate” to “high” levels of consensus.\nThe clinical guidelines include 27 recommendations. They are grouped by topic, and cover ongoing treatment for patients at varying degrees of COVID-19 exposure, including asymptomatic and symptomatic infection. Among the general guidelines is a recommendation that patients at high risk for chronic uveitis, or with a history of uveitis, continue with scheduled, in-person visits with slit-lamp examination. Children with rheumatic disease should also continue to receive routine childhood vaccinations, unless contraindicated by DMARD therapy, including the annual influenza vaccine, according to the guidelines.\nRegarding ongoing treatment of patients without COVID-19 exposure or infection, the guidelines state that NSAIDs, hydroxychloroquine, angiotensin-converting enzyme inhibitors/angiotensin II receptor blockers, colchicine, conventional DMARDs, biologic DMARDs and targeted synthetic DMARDs may be continued or initiated to control underlying disease. Glucocorticoids may also be continued or initiated, using the lowest dose possible to control underlying disease.\nFurther, for pediatric patients with life- or organ-threatening conditions, high-dose oral or intravenous “pulse” glucocorticoids and cyclophosphamide may be initiated to control underlying disease.\nIn pediatric patients with ongoing treatment who have had close or household exposure to COVID-19, the initiation of high-dose oral or intravenous glucocorticoids should be delayed for 1 to 2 weeks, if deemed safe by the treating provider, for those with non-life- or organ-threatening conditions. However, high-dose oral or intravenous glucocorticoids should not be delayed for patients with life- or organ-threatening disease.\nRegarding the ongoing treatment of pediatric patients with asymptomatic COVID-19, the ACR states that NSAIDs, hydroxychloroquine, colchicine, DMARDs, cyclophosphamide or rituximab may be continued, if necessary, to control underlying disease.\nAdditionally, in patients with confirmed COVID-19, DMARDs, except IL-1 and IL-6 inhibitors, should be temporarily delayed or withheld. According to the recommendations, IL-1 and IL-6 inhibitors may be continued, if necessary, to control underlying disease.\n“Multiple factors must be taken into consideration when interpreting these guidance statements including individual patient characteristics, underlying rheumatic disease, current disease activity, geography and current level of SARS-CoV-2 community transmission, duration and proximity of exposure to SARS-CoV-2 and severity of COVID-19 infection,” read the draft summary of the recommendations. “This guidance is presented as a ‘living document,’ recognizing that the current literature on COVID-19 is rapidly evolving. The ACR anticipates that these guidance statements will be updated as scientific evidence accumulates.”", "pred_label": "__label__POS", "pred_score_pos": 0.8887772560119629}
{"content": "Solar Radiation Management (SRM) is a controversial concept intended to address the symptoms of climate disruption (but not the causes). SRM would involve injecting particles in the stratosphere to prevent a small fraction of sunlight from reaching the earth’s surface. NRDC opposes deployment of SRM but believes some research is appropriate.", "pred_label": "__label__POS", "pred_score_pos": 0.9968404173851013}
{"content": "Beskrivning\nThis dissertation examines how melodrama, defined as a complex, distinctly modern and transnational mode of storytelling, has influenced the area of Polish Holocaust representation since the late 1970s till the present. Within a methodological frame that seeks to combine textual and contextual analysis, the study poses a set of questions that can be asked of the melodramatic mode’s narrative structures and stylistic devices, their signifying and functionality, in literature and film. Other key issues considered include the melodramatic narratives’ ability to evolve and adapt during the cultural transformation of late-communism (the 1970s and 1980s) and post-communism (after 1989), and the circumstances accompanying melodrama’s rise to prominence within this particular field. I argue that the increased visibility and popularity of melodramatic narratives must be seen in relation to the long-standing associations between Polish Holocaust representation and forms of expression linked to high modernism and the avant-garde, but also as indicative of fundamental changes in post-communist culture.", "pred_label": "__label__POS", "pred_score_pos": 0.907884955406189}
{"content": "Philanthropic support from generous individuals or trusts and foundations is one of the most powerful tools we have in the fight against poverty and inequality.\nA significant donation can have an incredible impact on education in rural Africa, and you will be playing a personal and pivotal role in helping us to deliver the life-changing opportunities that so many children deserve.", "pred_label": "__label__POS", "pred_score_pos": 0.9941481351852417}
{"content": "Recently, deep neural network (DNN) accelerators have received considerable attention due to reduced cost and energy compared to mainstream GPUs. In order to further reduce energy consumption, the included memory (storing weights and intermediate computations) is operated at low voltage. However, this causes bit errors in memory cells, directly impacting the stored (quantized) DNN weights. This results in a significant decrease in CNN accuracy. In this paper, we tackle the problem of DNN robustness against random bit errors. By using a robust fixed-point quantization, training with aggressive weight clipping as regularization and injecting random bit errors during training, we increase robustness significantly, allowing energy-efficient DNN accelerators.", "pred_label": "__label__POS", "pred_score_pos": 0.9997759461402893}
{"content": "Non-word reading is related to visual temporal attention What is it about?\nThe 'attentional blink' is an estimate of the time for a rapidly presented piece of item to reach conscious awareness in a context of interference. On average this takes about 500 milliseconds. A lot of research has suggested a relationship between the attentional blink and reading, especially in dyslexia. In our research we measured non-word reading (e.g., bormil) in a group of typically reading adults and found that it was related to the attentional blink, such that poorer readers took longer to recover from the attentional blink. Rather than being critical for the reading process, we suggest the relationship might be related to a common mechanism of attentional control.\nWhy is it important?\nThis paper supports a relationship between reading and the attentional blink in typically reading adults. It is particularly interesting because this relationship does not appear to hold in children or in groups of individuals with reading difficulties (or dyslexia). As part of our interpretation of the literature, we make a number of suggestions for followup research to better understand how the relationship between the attentional blink and reading changes with development.\nPerspectives\nThe following have contributed to this page: Dr Nicholas A Badcock", "pred_label": "__label__POS", "pred_score_pos": 0.624779462814331}
{"content": "Host shift events play an important role in epizootics as adaptation to new hosts can profoundly affect the spread of the disease and the measures needed to control it. During the late 1990s, an epizootic in Turkey resulted in a sustained maintenance of rabies virus (RABV) within the fox population. We used Bayesian inferences to investigate whole genome sequences from fox and dog brain tissues from Turkey to demonstrate that the epizootic occurred in 1997 (±1 year). Furthermore, these data indicated that the epizootic was most likely due to a host shift from locally infected domestic dogs, rather than an incursion of a novel fox or dog RABV. No evidence was observed for genetic adaptation to foxes at consensus sequence level and dN/dS analysis suggested purifying selection. Therefore, the deep sequence data were analysed to investigate the sub-viral population during a host shift event. Viral heterogeneity was measured in all RABV samples; viruses from the early period after the host shift exhibited greater sequence variation in comparison to those from the later stage, and to those not involved in the host shift event, possibly indicating a role in establishing transmission within a new host. The transient increase in variation observed in the new host species may represent virus replication within a new environment, perhaps due to increased replication within the CNS, resulting in a larger population of viruses, or due to the lack of host constraints present in the new host reservoir.\nKeywords: cross-species transmission; lyssavirus; next generation sequencing; rabies virus; viral heterogeneity; whole genome sequencing.", "pred_label": "__label__POS", "pred_score_pos": 0.651486873626709}
{"content": "The study accesses the availability of lecture halls on academic activities of Osun State Polytechnic Iree students. Survey research method was used and questionnaire was administered to 100 respondents which were picked across the faculties using accidental sampling method. The data collected were analysed using frequency and percentage method. Findings show that OSPOLY is boasted of several lecture halls, although, not at the most conducive status due to poor ventilation, inadequate fans, poor address system, overcrowding and lots more. It is noted that good learning environment enhances learning, promote love for academic, reduce boredom and enhance concentration while poor learning environment create the opposite. Therefore, to a large extent; learning environment do have significant impact on students performance. It is recommended that management of Osun State Polytechnic Iree should make teaching and learning more conducive by providing the needed facilities such as light, good seats and tables, loudspeaker, projector and so on while more lecture halls should be built.\nExtraction is an abstract", "pred_label": "__label__POS", "pred_score_pos": 0.5325197577476501}
{"content": "This Note defines impact evaluations, explains when they should be commissioned according to USAID policy and describes different designs for quasi-experimental and experimental impact evaluations. USAID is updating the 2013 Technical Note on Impact Evaluations. Stay tuned for the updated content in 2020.\nThis resource provides guidance and a template for developing a Performance Management Plan (PMP) task schedule.\nCLA and Developmental Evaluations\nQualitative Methods and Approaches\nComparing Sampling Strategies\nStacey Young, from USAID's Office of Learning, Evaluation and Research, provides detailed information about collaborating, learning and adapting within the Program Cycle.\nThis webinar featured PPL, regional, and technical bureau representatives who have participated and led evaluation statement of work (SOW) peer reviews. They discussed good practices in conducting peer reviews and how to get the most out of the process, resulting in a strong SOW with buy-in from key stakeholders.\nThis guidance provides information on conducting an After Action Review (AAR), including goals, assumptions/requirements, how tos, lessons learned/best practice, and resources.\nThe Millennium Development Goals (MDGs) are a symbol of our common humanity.\nWritten for non-profits, implementing partners can use this to support their monitoring, while USAID can use it for learning about their programs through monitoring CDCS/ CLA.", "pred_label": "__label__POS", "pred_score_pos": 0.988760232925415}
{"content": "This article introduces three small, European stateless nations that – invigorated by pervasive metropolitanisation phenomena – are increasingly shaping calls for devolution: Catalonia, the Basque Country and Scotland. These three nations are re-scaling their respective nation-states (Spain and the UK) in different ways: (i) being bolstered by their metropolitan hubs (Barcelona, Bilbao, and Glasgow) and (ii) generating a stateless ‘civic nationalism’ rooted in the metropolitan ‘right to decide’. Oppositional response to this ‘civic nationalism’ has re-emerged as state-centric ‘ethnic nationalism’. This article concludes that gaining or lacking metropolitan support for the ‘right to decide’ will establish the future directions of devolution debates.\nCalzada, I. (2018), Metropolitanising Small European Stateless City-Regionalised Nations.\nSpace and Polity (3): 342-361 22 First Published 14 Dec 2018", "pred_label": "__label__POS", "pred_score_pos": 0.9950347542762756}
{"content": "The Environment Agency has reported potential algal bloom in the River Stort between Lower Sheering and Roydon Park.\nA natural phenomenon\nAlgae blooms are a natural phenomenon. Under certain weather conditions it can bloom in large volumes, cutting off the oxygen supply in rivers and lakes.\nIf the outbreak is serious, it can lead to the death of fish and other organisms. Algal blooms can also be toxic to wild animals, people and pets.\nEnvironment Agency Officers will continue to monitor the situation and deploy additional resources if necessary. Members of the public are advised to stay away from any water courses showing signs of a bloom – typically cloudy or less clear green water and dead fish.\nIt can also look blue-green or greenish-brown. Scums can form during calm weather when several bloom forming species rise to the surface. This can look like paint, mousse or small clumps.\nEnvironment Agency guidance\nAnyone seeing signs of the algae on the River Stort should report occurrences to the\nEnvironment Agency Incident Communications Service: Call 0800 80 70 60 quoting reference 01801279 Keep up to date\nKeep in touch with our latest news, service updates and reports.", "pred_label": "__label__POS", "pred_score_pos": 0.6747859120368958}
{"content": "March.24.2010\nOn March 22, 2010, the United States Court of Appeals for the Third Circuit issued a decision in the bankruptcy case for Philadelphia Newspapers, LLC and its affiliates (collectively, the “Debtors”). The Third Circuit affirmed the district court’s opinion approving proposed bidding procedures for an auction sale under the Debtors’ plan of reorganization which prohibited secured lenders from “credit bidding” their debt in lieu of cash. This decision has significant implications for issuers of secured credit.\nThe Debtors filed voluntary petitions for chapter 11 relief in 2009. On August 20, 2009, the Debtors filed a joint plan of reorganization. The plan provided for the sale of substantially all of the Debtors’ assets at a public auction. The assets were to be sold free of secured lenders’ liens and the proceeds of the sale were to be distributed to the Debtors’ secured lenders on account of their secured claims.\nOn August 28, 2009, the Debtors filed a motion for approval of the bidding procedures for the proposed auction. The bidding procedures required all qualified bidders to fund their offers with cash. The practical effect of this restriction was to deny secured lenders the opportunity to “credit bid” their debt and offset the amount they are owed against the purchase price of the assets. The Debtors’ secured lenders objected.\nThe dispute between the Debtors and their secured lenders centered on section 1129(b) of the Bankruptcy Code. Section 1129(b)(1) provides that a bankruptcy court can confirm a plan of reorganization over the objections of secured creditors who vote to reject the plan, but only if the plan is “fair and equitable” to the creditors. Under section 1129(b)(2), a plan must satisfy certain minimum requirements to be considered “fair and equitable.” One way to meet those requirements is to organize a sale of the secured creditors’ collateral free of liens and grant the secured creditors an opportunity to credit bid (the “First Option”). A second, alternative way to fulfill the requirements is to provide the secured creditors with the “indubitable equivalent” of their secured claims (the “Second Option”).\nThe secured lenders argued that because the Debtors’ plan provided for a sale of their collateral free of liens—ostensibly pursuing the First Option—the plan could not be considered “fair and equitable” unless the secured lenders received an opportunity to credit bid at the auction. The Third Circuit disagreed. Focusing on the “plain meaning” of section 1129(b)(2), the Third Circuit held that the Debtors’ plan could still qualify as “fair and equitable” under the Second Option if the proposed auction generated the “indubitable equivalent” of the secured lenders’ claims. Given that the auction had not yet taken place, the Third Circuit concluded that it was not in a position to say, as a matter of law, that the Debtors’ plan would not be “fair and equitable.”\nFor secured creditors, the right to credit bid at a sale of their collateral constitutes an important protection against the risk that the collateral will be undervalued. Although arguably narrow in scope, the Third Circuit’s decision calls this protection into question. Indeed, in a related decision in the bankruptcy case for Pacific Lumber Company and its affiliates, the United States Court of Appeals for the Fifth Circuit recently held that a plan which provided for the sale of the debtors’ assets without allowing secured creditors to credit bid ultimately was “fair and equitable.”", "pred_label": "__label__POS", "pred_score_pos": 0.9872627258300781}
{"content": "Building Capacity of Staff\nAll Ulster BOCES Student Based Programs leadership teams, in collaboration with their site based wellness team and providers such as Ramapo for Children and Instructional Services, will design on-going professional development for all staff; addressing safety and wellness during the ongoing COVID-19 public health emergency.\nSuch school based professional development and intervention strategies shall build individual capacity in the context of the school community, develop empathy and resilience and understanding of restorative practices for students, faculty, and staff. This planning will include appropriate child-centered and developmentally appropriate responses to non-compliance of safety practices. Professional development will be offered on, but not limited to:\nCOVID-19 Support Social Justice - The need for professional development and discussion regarding:\na unified message, through the use of positive messaging and signage, across all school based programs, training and support for staff in educating students to be up-standers and allies in promoting equity and inclusion, explicit and implicit bias in our programs, and learning how to support students who have experienced or witnessed race, gender, or LGTBQ based discrimination in or out of schools should be outlined. Social & Emotional Learning - Focusing on 5 competencies:\nSelf-awareness Self-management Social awareness Relationship skills Responsible decision-making Transformative SEL elaborates on Social Emotional Learning focusing on\nbeing culturally and linguistically responsive and equitably meeting the needs of students and adults, including the implications of culture, identity, agency, belonging, and engagement. Restorative Practices Build on existing strengths. Address behavior from a whole-child perspective, developing the above SEL competencies, guided by sensitivity toward Adverse Childhood Experiences (ACES) and trauma-informed practices. Implement processes and approaches designed to build and repair meaningful relationships. Wellness Supports for all staff - Additional supports for staff wellness shall include:\naccess to the Employee Assistance Program (EAP) through the BOCES agency ongoing wellness supports provided by Instructional Services. Specific Trauma-informed supports, both proactive and responsive, needed for all staff, being mindful to include itinerant service providers, and IS staff. Specifically train staff who will interfacing with students at arrival and visitors throughout the school day. Sensitivity needs to be developed in care for fragile students and visitors.", "pred_label": "__label__POS", "pred_score_pos": 0.5968170166015625}
{"content": "Availability: In stock (2)\nNeptune Krill Oil (NKO) is known for its unique fatty acid (FA) profile, as well as for its rich antioxidant content. NKO's balanced fatty acid content includes not only EPA and DHA, the crucial Omega-3 FA's, but Omega-9 FA's and phospholipids, as well. NKO is a rich source of Astaxanthin, a powerful immune-supporting antioxidant. Clinical studies have shown that NKO can support joint comfort, healthy blood lipid levels, and may reduce symptoms of pre-menstrual syndrome.\nNeptune Krill Oil is manufactured under strict quality control standards. It is tested to be free of potentially harmful levels of contaminants (i.e. mercury, heavy metals, PCB's, dioxins, and other contaminants).\nFeatures:", "pred_label": "__label__POS", "pred_score_pos": 0.5717452764511108}
{"content": "Abstract\nCadherin is a cell-surface transmembrane receptor that mediates calcium-dependent cell-cell adhesion and is a major component of adhesive junctions. The formation of intercellular adhesive junctions is initiated by trans binding between cadherins on adjacent cells, which is followed by the clustering of cadherins via the formation of cis interactions between cadherins on the same cell membranes. Moreover, classical cadherins have multiple glycosylation sites along their extracellular regions. It was found that aberrant glycosylation affects the adhesive function of cadherins and correlates with metastatic phenotypes of several cancers. However, a mechanistic understanding of cadherin clustering during cell adhesion and the role of glycosylation in this process is still lacking. Here, we designed a kinetic model that includes multistep reaction pathways for cadherin clustering. We further applied a diffusion-reaction algorithm to numerically simulate the clustering process using a recently developed coarse-grained model. Using experimentally measured rates of trans binding between soluble E-cadherin extracellular domains, we conducted simulations of cadherin-mediated cell-cell binding kinetics, and the results are quantitatively comparable to experimental data from micropipette experiments. In addition, we show that incorporating cadherin clustering via cis interactions further increases intercellular binding. Interestingly, a two-phase kinetic profile was derived under the assumption that glycosylation regulates the kinetic rates of cis interactions. This two-phase profile is qualitatively consistent with experimental results from micropipette measurements. Therefore, our computational studies provide new, to our knowledge, insights into the molecular mechanism of cadherin-based cell adhesion.\nASJC Scopus subject areas Biophysics", "pred_label": "__label__POS", "pred_score_pos": 0.8203048706054688}
{"content": "“Collective Leadership effectiveness drives business performance.” William A. Adams\nGrowing Organisations works with you to identify business challenges and design leadership development programmes to build effective leadership networks and high performing teams in your company.\nToday’s leaders must adapt to stay relevant in a constantly changing environment. As business cycles, contexts, people, resources, technology, and competition change, leaders cannot stick to a limited repertoire of learned skills and apply them indiscriminately expecting good results each time.\nTo be truly effective leaders we must always keep our purpose in mind, deeply understand our essence, and continuously learn our forms. We become versatile, grounded, and resilient.", "pred_label": "__label__POS", "pred_score_pos": 0.7391481399536133}
{"content": "Catalog Video Catalog Practice-based arts research in repositories: how do we better engage with researchers to capture, manage and enable discoverability of this research?\nRepositories have historically focused on supporting traditional text-based outputs in STEM areas, capturing and making individual research publications openly available, and more recently the underpinning datasets. Funder policies focus on these outputs, resulting in greater awareness and usage of repositories amongst STEM researchers.\nPractice-based arts research tends to be in non-text formats, and is often part of a wider, changing portfolio of work (including the original artefact and related documentation), elements of which may be captured in a publications repository, with associated documentation held in a data repository. This has often led to fractured discussions: those on open access take place in different forums to those on research data; and different teams may support these areas, including libraries, archives and research offices.\nMuch work has been done to customise repositories to more effectively capture this research. However, barriers to effectively engage with this community remain. Specific functionality requirements and issues include: records that enable open metadata and closed files; portfolios representing a changing body of work need updating over time; issues with file sizes and types, image quality and video streaming; restrictions imposed by repository software architecture, and interoperability with CRIS systems; and concerns with intellectual property rights and copyright.\nDeepGreen – Pushing on the Green Road of Open Access12.06.2019", "pred_label": "__label__POS", "pred_score_pos": 0.9394542574882507}
{"content": "Podcast: Balancing Exploration and Use of Space Beyond Earth Orbit\nOur “Beer with BMSIS” podcast for February features a conversation with Dr. Margaret Race of the SETI Institute about some of the challenges facing astrobiology and space exploration titled “More Bumps in the Road Ahead for Astrobiology?: Balancing Exploration and Use of Space Beyond Earth Orbit“.\nCommercial space exploration has come along way since the days NASA’s moon landing, and commercial interests in the moon, Mars, asteroids, and other space resources must now be taken as seriously as national space exploration programs. Existing laws and treaties are limited in scope and provide unclear guidelines for how best to proceed with the exploration and utilization of space resources. Dr. Race discusses various considerations and options for future exploration, drawing from insights from history that include the Antarctic Treaty and the Law of the Sea, to discuss how existing treaties might be modified as the space age continues.", "pred_label": "__label__POS", "pred_score_pos": 0.8780986070632935}
{"content": "In 2019, tax burden increased 4.0% in nominal terms, attaining 74 billion euros, corresponding to 34.8% of GDP (the same ratio in the previous year). Excluding taxes received by the European Union Institutions, Portugal continued to register in 2019 a lower tax burden than the EU average (34.7% compared to 39.4% in the EU28).\nSocial contributions were the category that contributed the most to the tax burden increase, with an annual change of 7.7%. Indirect taxes revenue increased 3.8%, while direct taxes revenue increased only 0.9%. Regarding direct taxes revenue, there was an increase of 2.0% in individual income tax (IRS) while revenue from corporate income tax (IRC) fell by 2.9%. Value added tax (VAT) revenue increased by 5.4%. Regarding the remaining indirect taxes, it should be highlighted the increase observed in revenue from the stamp tax (7.6%). More moderate growths were registered in revenue from real estate transfer tax collected by Local Government (3.0%), from tax on oil and energetic products (2.6%) and from real estate tax collected by Local Government (1.1%). Revenues from excise duties on tobacco and from tax on motor vehicle sales fell 6.0% and 5.3% respectively. In 2017, the most recent year with detailed information for its compilation, the VAT gap was estimated at 481 million euro, corresponding to 2.8% of the VAT revenue of the year, diminishing 3.0 percentage points comparing with the amount estimated for the previous year (972 million euro).", "pred_label": "__label__POS", "pred_score_pos": 0.7479057312011719}
{"content": "Homeowners’ insurance often includes coverage for wind damage. Coverage will include damage to a home’s structure, such as the roof or windows, along with personal property damaged by wind. Some policies also will include windstorm damage caused by a hurricane or tornado. A deductible and coverage limit likely will apply and vary by policy.", "pred_label": "__label__POS", "pred_score_pos": 0.999992311000824}
{"content": "One of the finest examples of powerful religious oration is Mother Teresa’s 1994 sermon at the National Prayer Breakfast in Washington, D.C. Through this sermon, the Nobel Peace Prize winner offered strong opinions and inspired the audience with her words of faith. You can watch the video, available on YouTube, if you need inspiration and have half an hour to spare. But if you don’t, how else might you get the essence of her sermon quickly and easily?\nYou could read transcripts. Sermon transcripts allow an audience to scan sermons for key points and compelling phrases. They make sermons easily accessible and enable those who are deaf or hard of hearing to enjoy the message, too.\nTranscripts deliver these benefits and more. But should you be the one to transcribe the sermons you deliver? If you’re interested in efficiency or in having more time to write your sermons, probably not. Instead, rely on a transcription service to transcribe your audio to text.\nPreparing a sermon takes long enough. You have to determine its purpose. You have to compile notes and relevant scriptures, craft an introduction and conclusion, integrate examples and quotations, and inspire unity with your words. After writing your sermon, you have to practice and refine your delivery. These are the tasks you should focus on. A professional transcriptionist can handle preparing sermon transcripts for you.\nA reliable transcription service will save you vast amounts of time. People often underestimate (sometimes severely) the time it takes to prepare a detailed sermon transcript. A sermon you deliver in forty minutes could take a transcriptionist up to four hours to convert to text, including transcribing, formatting, and proofreading. Your time is better spent making your sermon more powerful.\nA service that specializes in sermon transcripts will produce an accurate text that audiences can enjoy at their own pace whenever they want. They can save the transcript for later reference or share it with family members and friends, putting your words in front of more people.\nDon’t try to take on too much. Invest wisely in services such as sermon transcription that can save you time and allow you to focus on what’s most important—writing and delivering your sermon.", "pred_label": "__label__POS", "pred_score_pos": 0.6298998594284058}
{"content": "With the price of resources and energy becoming increasingly volatile, can today’s linear economy work in the long term?\nWhat if we didn’t buy the goods we use, but instead favoured access and performance over ownership? This short animation from the Ellen MacArthur Foundation introduced the idea, and suggests how it could work for businesses, users, and the wider economy.", "pred_label": "__label__POS", "pred_score_pos": 0.7978553771972656}
{"content": "When 5 million barrels of oil spill into the ocean, something bad was obviously going to happen. However, no one really knew how deep the oil would penetrate and how much damage it could cause.\nThe scientists do need further tests to prove that these dead coral reefs are directly related to the BP Oil Spill but given the evidence—proximity to the BP Oil Spill (7 miles southwest), the previous presence of oil plumes and the matter of which the coral reefs died—the scientists believe there's a pretty strong link. According to Charles Fisher, chief scientist on the gulf expedition:\nOil seeps naturally from the seafloor throughout the Gulf of Mexico, but that was unlikely to have caused such a severe coral die-off, he added. \"We have never seen anything like this at any of the deep coral sites that we've been to,\" Dr. Fisher said. \"And we've been to quite a lot of them.\"\nLooks like the after-aftereffects of the Oil Spill are trickling in. [NY Times]", "pred_label": "__label__POS", "pred_score_pos": 0.6337383985519409}
{"content": "Abstract\nPurpose/Objective: To investigate the feasibility of brain- computer interface (BCI) with patients on an inpatient spinal cord injury (SCI) unit. Research Method/Design: This study included 25 participants aged 18-64 who sustained traumatic or nontraumatic SCI and did not have severe cognitive or psychiatric impairment. Participants completed a variety of screening measures related to cognition, psychological disposition, pain, and technology experience/interest. The Emotiv electroencephalography system was used in conjunction with a cube rotation and manipulation game presented on a laptop computer. Results: The majority of participants successfully completed the BCI game and reported enjoyment of the experience. Outside of a mild trend of lower performance among participants with a past or present head injury, there were no demographic variables, injury variables or screening measures significantly associated with BCI performance. Conclusions/Implications: The BCI paradigm demonstrated feasibility and safety across participant age range, educational and vocational background, and level of injury. Despite the rapid integration of technology into rehabilitation health care settings, there are few evidence-based studies regarding the feasibility of technology with specific inpatient populations. Clinical implications and challenges of using this technology in a rehabilitation setting are discussed.\nKeywords Disability Inpatient rehabilitation Technology Virtual reality", "pred_label": "__label__POS", "pred_score_pos": 0.9634987711906433}
{"content": "NAC\nSold Out\nEssential for making the powerful antioxidant Glutathione Potent Detoxification nutrient Relief of Respiratory symptoms (phlegm, cough, sinus congestion) Boosts Brain Health by Regulating Glutamate and Replenishing Glutathione Improves fertilityin both Men and Women Decreases risk for Oxidative damage Leaky Gut Support SIBO Support: Gut permeability MTHFR Gene Support (Methyl Tetra Hydro Folate Reductase) N-Acetyl-Cysteine (NAC) is a source of the conditionally essential amino acid L-cysteine and a precursor to the tripeptide glutathione.\nNAC and glutathione support antioxidant and detoxification activity in the body.\nNAC is recognized for its support of normal mucous production and may positively support respiratory function and eye health, especially when consumed over a prolonged period.\nResearch suggests that NAC may protect cell and tissue health by supporting normal heavy-metal status in the body.\n******\nRecommended Dosage: Take one to two capsules twice daily between meals, or as directed by your healthcare practitioner. Quantity: 120 capsules Ingredients: Does Not Contain: Wheat, gluten, corn, yeast, soy, animal or dairy products, fish, shellfish, peanuts, tree nuts, egg, artificial colors, artificial sweeteners, or preservatives. Caution:Children and pregnant or lactating women should consult their healthcare practitioner prior to use. Do not use if tamper seal is damaged. Storage: Keep closed in a cool, dry place out of reach of children.", "pred_label": "__label__POS", "pred_score_pos": 0.556475043296814}
{"content": "Northeastern University President Joseph E. Aoun is leading a coalition of higher education leaders throughout the country to urge the Obama administration to preserve the Perkins student loan program, which benefits more than 500,000 low-income college students each year.\nIn a letter to U.S. Secretary of Education Arne Duncan, President Aoun and 32 presidents and chancellors from other institutions, along with the American Association of University Professors, call for a commitment to continuing and strengthening the program, which faces an uncertain future. According to a recent statement by the Department of Education, the Perkins loans would continue only through 2014.\nThe group emphasized the importance of maintaining the program in the long term, and expressed a willingness to collaborate with the department to ensure that the neediest of students reach their dreams of attending college.\n“While we greatly appreciate the department’s recent announcement that the Perkins Loan program will now be authorized through 2014, we remain concerned about the long-term viability of the program,” the letter reads. “Ending this program would be directly at odds with President Obama’s ambitious goal for the U.S. to have the highest proportion of college graduates in the world by 2020. To achieve this goal, it is essential that students have maximum access to low-cost college financing options, including Perkins loans. We are deeply concerned that if the program is eliminated in 2014, fewer students will attend college, more will drop out, and the level of high-interest debt will increase for many more students.”\nThe letter lauds the success of the Perkins program, which provides more than $1 billion a year in need-based aid to students enrolled in nearly 1,800 participating colleges and universities. It also notes the higher education community’s strong commitment to the Perkins program, even in the absence of new federal capital contributions since 2004.\nIn their letter, President Aoun and the group acknowledged the efforts of Congress and the Obama administration last year to reinvigorate the program as part of a larger student loan reform bill. But it was ultimately dropped from the legislation.\n“[We] look forward to working with you to preserve the benefits of the Perkins loan program and help America emerge, once again, as the nation with the highest proportion of college graduates in the world,” the letter reads.\nThis campaign continues President Aoun’s leadership in addressing critical higher education issues on the national stage. Last April, he led a group of college presidents in urging caution amid the U.S. Department of Labor’s plan to regulate unpaid internships. In his letter to U.S. Secretary of Labor Hilda Solis — signed by 13 college presidents — he argued for protecting the value of experiential learning. As the president of Northeastern — a world leader in experiential learning and co-op — he lauded the demand for this powerful way of learning as a growing number of colleges and universities are expanding and integrating internships into their curriculum.\nClick here to read The Boston Globe’s coverageof President Aoun’s efforts to protect low-interest loans", "pred_label": "__label__POS", "pred_score_pos": 0.6524319648742676}
{"content": "The Bigger Picture\nPersonal finance, retirement, and other resources\nNHRS provides a lifetime benefit to eligible members, however, the pension is only one component of a secure retirement. While the retirement system cannot provide individual financial planning advice, we encourage all of our members to take a proactive role in understanding their personal financial needs and preparing for their retirement.\nThis page lists resources on retirement planning and overall financial literacy from governmental, non-profit, media, and public service entities. While the emphasis is on preparing for retirement, many of these links are relevant regardless of age.\nClick on the subject headings to view specific content.\nFinancial literacy | Social Security\nSupplemental retirement savings | Financial & investment advice Health insurance/Medicare | Protecting against scams | Retiree resources\nDisclaimer: This page is intended as an informational tool only. Links to third-party sites are provided as a service for our members and retirees. The links provided are not maintained by NHRS or affiliated with any services provided by the retirement system. We make no endorsement, express or implied, of the content or activities of any linked sites. Questions should be directed to the administrator(s) of each specific site.", "pred_label": "__label__POS", "pred_score_pos": 0.6405190229415894}
{"content": "Covering Stucco With Vinyl\nI have a 30-year-old house with stucco exterior walls. I want to cover the walls with vinyl siding, but I have no idea what is between the stucco exterior walls and the interior drywalls. Is it necessary to insulate before installing the vinyl siding?\nThis is a great opportunity to insulate your house effectively. Insulating walls can be a laborious and expensive project, but if you need to change the siding anyway, insulation is an easy add-on. If you do not know what is in between the walls, simply drill a hole and find out. In the end the hole will not matter because you will be covering it with the siding. If the house is about 30 years old, when you punch a hole through the wall you will likely find the space between the walls filled with fiberglass. If it is not, then this is the first thing that you should do. After you have sealed the hole, apply 2.5 cm (1 in.) thick sheets of rigid foam insulation over the stucco exterior walls. Over that install the vinyl siding. You will then have a double layer of insulation that can definitely end up reducing your heating costs.", "pred_label": "__label__POS", "pred_score_pos": 0.7589031457901001}
{"content": "Radiographs and CBCT are valuable diagnostic tools to help you determine the presence of a root fracture. Unfortunately, unless the fracture is wider than about .15 mm (the tip of a #15 endodontic file), it cannot be visualized on the CBCT scan. However, there are some strong associations between radiographic findings and the presence of a root fracture. Specifically, when the bone loss presents in “J” shaped pattern, it is highly suggestive that a root fracture is present. Often, this can be seen on a two-dimensional periapical radiograph with the bony lesion typically extending from the apex to the crestal bone, sometimes resulting in a deep and narrow isolated periodontal pocket. Sometimes this pocket cannot be probed because it occurs in the interproximal area.", "pred_label": "__label__POS", "pred_score_pos": 0.9997414350509644}
{"content": "As the common saying goes, if individuals enjoy their job, they never work a day in their life. While it is good for Marylanders to find careers they enjoy, employees should ensure that they do not get carried away and engage in risky horseplay.\nMany workplace policies directly state that they do not allow horseplay in the workplace. But violating company policy is not the only risk involved in horseplay. Pranks or roughhousing on the job can significantly increase the chance of suffering an injury at work. And injuries resulting from these actions are not covered under workers’ compensation.\nAn injury at work does not make it work-related\nMany people might think that any work-related injury could entitle them to collect workers’ compensation. However, injuries are only work-related if they arise out of the course of employment. This essentially means that injuries are only covered if it happened while:\nThe individual was at work The individual was performing their work duties\nHorseplay might happen at work. But it rarely happens while employees are actually working.\nWhat is considered horseplay?\nHorseplay usually involves unsafe and reckless playing or pranks. This rough play often means physical contact and exertion that increases the risk of injuries.\nAnd employers, insurers and the Workers’ Compensation Commission consider a few factors to separate other work injuries from horseplay injuries. These variables include:\nDetermining what the company policy states Proving the employee knew the policy, but still engaged in horseplay Providing proof that the employee understood the risk of injury Verifying that this individual’s injury resulted from their disregard of the rule What if you did not participate in horseplay?\nIf workers suffer injuries while engaging in reckless horseplay at work, they often are not entitled to compensation. But what about other employees who were not involved?\nUnfortunately, the recklessness of others often puts bystanders at risk of an injury as well. But injured individuals who did not engage in horseplay might be able to apply for workers’ compensation. Maryland workers’ compensation law includes “willful or negligent acts” by others in the definition of covered work injuries (Maryland Code, Labor & Employment §9-101).\nThe law may cover these injured employees. However, work injuries resulting from another’s horseplay can be difficult to prove. It is beneficial for employees in these situations to retain an experienced workers’ compensation attorney to recover their benefits.", "pred_label": "__label__POS", "pred_score_pos": 0.9294766187667847}
{"content": "It is an information stealer that uses a stealthy trick to evade detection from security software and steal personal data of victims including their usernames, passwords, bank details, and contents of cryptocurrency wallets – using a keyblogger that would monitor browser and desktop activities.\nRecently, the U.S. government's cybersecurity and Infrastructure Security Agency (CISA) observed a significant increase in malicious infections via LokiBot malware starting from July 2020. During this period, CISA's EINSTEIN Detection System, responsible for protecting federal, civilian executive branch networks, noticed continuous malicious activity by LokiBot. Credited for being simple yet effective, the malware is often sent out as an infected attachment via email, malicious websites, texts, or personal messages to target Windows and Android operating systems.\nAlthough LokiBot has been in cyberspace for a while now, attackers still often use it to illicitly access sensitive information. In a recent attack that was carried out in July, 14 different campaigns distributing payloads of LokiBot were launched by a group of threat actors popularly known as 'RATicate'. In another malspam campaign, attackers were found to be distributing payload of LokiBot in a spear-phishing attack on a U.S based manufacturing organization.\n“LokiBot has stolen credentials from multiple applications and data sources, including Windows operating system credentials, email clients, File Transfer Protocol, and Secure File Transfer Protocol clients,” as per the alert issued on Tuesday.\nGiving insights on the matter, Saryu Nayyar, CEO at Gurucul told via email, \"The fact that LokiBot has been around for over four years and has gained in capability over time is a reflection of how much malicious actors have advanced the state of their art, leveraging the same development models we use in the commercial space.\"", "pred_label": "__label__POS", "pred_score_pos": 0.9836976528167725}
{"content": "In Virginia, any violation of controlled substance laws is prosecuted aggressively. Being charged with distributing drugs to a minor is a serious felony offense, and the punishment can include a lengthy prison sentence and a large fine. If you have been arrested for this crime, you need to retain an experienced criminal defense attorney as soon as possible to help you get the charges dismissed or reduced to a less serious offense.\nWhat Is the Penalty for Distributing Drugs to a Minor?\nUnder Virginia Code § 18.2-555, it is a felony crime to distribute controlled substances to a minor. Here are ways that an individual who is 18 years old or older can violate this law:\nBy intentionally or knowingly distributing any drug classified as a Schedule I-IV drug or marijuana to a person under 18 years old who is at least three years younger than him. By intentionally or knowingly causing a person under 18 years old to assist in the distribution of a Schedule I-IV controlled substance.\nIf convicted, an individual faces harsh penalties that include a mandatory minimum prison sentence. Here are the potential sentences for violations of Virginia Code § 18.2-555:\nThe sentence for distributing drugs to a minor or causing a minor to assist in distributing them is a prison sentence of not less than 10 years and not more than 50 years and a fine not to exceed $100,000. If the conviction is for a Schedule I or II controlled substance or one or more ounces of marijuana, there is a mandatory minimum sentence of five years in prison. Examples of Schedule I and II drugs include heroin, PCP, ecstasy, cocaine, and opium. If the conviction involves less than one ounce of marijuana, there is a two-year mandatory minimum sentence.\nIt is also a crime to distribute to or cause a minor to assist in distributing an imitation controlled substance. This is a Class 6 felony with a sentence range of one to five years in prison and a $2,500 fine.\nAre you being charged with a drug offense in Fairfax or Northern Virginia? Call our office to schedule a free consultation with our experienced criminal defense attorneys to learn about your options and how we can help you put on a strong defense to the charges you face.", "pred_label": "__label__POS", "pred_score_pos": 0.6561099290847778}
{"content": "Seeks to assess the relationship between resources allocated to frontline police working in stations throughout metropolitan and regional SA, their ability to do their job (i.e. workload) and their well-being (morale, job satisfaction, level of distress). The study also sought to gain insights into the psychological risks to worker wellbeing associated with current resourcing, organisational and operational demands within SA Police - this understanding was seen as crucial to ensuring adequate resourcing for officers. Further, it was viewed as a crucial underpinning to the development of policies which enhance the occupational health and safety of the frontline police officers who bear the burden of protecting the South Australian community from crime and criminal behaviour.\nShow More", "pred_label": "__label__POS", "pred_score_pos": 0.9989427328109741}
{"content": "Abstract\nThis study extends literature on e-commerce trust and repurchase intentions by exploring the role of swift guanxi and the perceived effectiveness of institutional mechanisms (PEEIM) in the context of a Chinese e-marketplace − Taobao. We explore how Taobao’s social media technologies (online reviews and instant messenger) can improve swift guanxi and PEEIM by increasing online interactivity and presence. We find that buyers' PEEIM negatively moderates trust in online sellers and repurchase intentions. We show that swift guanxi, created by social media's interactivity and presence, enhances trust, which further increases repurchase intentions. Theoretical and managerial implications and future research directions are discussed.\nKeywords online marketplace trust institutional mechanisms swift guanxi interactivity social presence", "pred_label": "__label__POS", "pred_score_pos": 0.9882559180259705}
{"content": "An investigational topical treatment for peanut allergy in children has shown promising long-term efficacy.\nIn the study, the initial protocol escalated the oral challenge of peanut protein until hypersensitivity symptoms were elicited. After 3 years of treatment, 75.9% of children aged 4 to 11 had increased the “eliciting dose” (ED) of peanut protein.\nThe primary efficacy outcome was the difference in responder rate with active treatment versus placebo, with a caveat that the lower boundary to the 95% confidence interval had to be no lower than ≥15 percentage points. Responders were those who maximally tolerated peanut protein at a dose of 300 mg at 12 months if baseline tolerance was ≤10 mg, or 1,000 mg if baseline tolerance was >10-300 mg.\nAlthough there was a significant difference in responder rate, the risk difference missed the prespecified statistical component.\nAll participants who reached an eliciting dose ≥1000mg at month 36 were eligible to continue the study for an additional two months without treatment while maintaining a peanut-free diet. A double-blind, placebo-controlled food challenge to determine the 'eliciting dose' (ED) was then given at month 38. The analysis revealed that 77.8 per cent maintained desensitisation with an ED ≥1,000mg.", "pred_label": "__label__POS", "pred_score_pos": 0.894768238067627}
{"content": "Over the past year our factory in Malawi, which we operate with our partners Exagris Africa, has produced 3 million sachets of Ready to Use Therapeutic Food (RUTF), sufficient to treat around 25,000 children with\nSevere Acute Malnutrition (SAM).\nDespite these figures it has been a difficult year due to a poor groundnut harvest. Peanut paste is a key raw material for RUTF and the quality need to be extremely high. We have struggled to maintain a consistent supply of paste and in response to this we have made several changes with our suppliers. While it will take some time to see the benefits materialise, we remain optimistic on the longer term outlook. Demand for RUTF remains high and if we can produce, the volume opportunities are there.\nWith the help of a grant from USAID’s South African Trade Hub (SATH), we plan to start pilot production of a Ready-to-use Complementary food (RUCF) in Malawi very soon.\nWhat is RUCF? RUCFs are designed to prevent chronic malnutrition which affects 43% of all children in Malawi and on average over 40% of all children in sub Saharan Africa. We intend to undertake a test market project using RUCF in Malawi, which will focus on addressing the process used to reach children affected by Chronic Malnutrition using a customer and market driven approach. This is the first step in a very ambitious programme we have lined up for 2015 to start the process of unlocking this potentially massive market.", "pred_label": "__label__POS", "pred_score_pos": 0.9391958117485046}
{"content": "Imaging cirrhotic patients for early detection of hepatocellular carcinoma remains a challenging issue despite many technological advances. In fact, nonmalignant hepatocellular lesions, such as regenerative or dysplastic nodules, may mimic a small tumor. Imaging protocols are aimed at showing the different vascular supply to the lesion. It is accepted that dynamic contrast-enhanced imaging techniques, including contrast ultrasound, multidetector computed tomography and magnetic resonance imaging, can establish the diagnosis of hepatocellular carcinoma in nodular lesions larger than 1 cm showing arterial hypervascularization with venous washout. Magnetic resonance imaging in combination with liver-specific contrast agents, including hepatocyte-targeted and reticuloendothelial system-targeted agents, may be useful to clarify questionable cases, due to its ability to show changes in hepatobiliary function or Kuppfer cell content associated with malignancy. However, even optimized imaging techniques remain relatively insensitive for the detection of tiny satellite nodules associated with the main tumor\nAutori interni: Autori: Lencioni R; Crocetti L; Della Pina MC; Cioni D Titolo: Guidelines for imaging focal lesions in liver cirrhosis Anno del prodotto: 2008 Appare nelle tipologie: 1.1 Articolo in rivista", "pred_label": "__label__POS", "pred_score_pos": 0.9790966510772705}
{"content": "Even though most people agree that testing software UI is important, many believe that automated tests are slow and unstable. Consequently, many technology companies prefer manual testing. I'll convince you otherwise in this post: even though automating UI tests and ensuring that they are fast and reliable is tough to accomplish, it’s definitely doable.\nI once asked a friend why his company didn't automate UI testing. He replied, “Because the tests break easily. For example, if an engineer changes something in the DOM, it causes errors in the tests.”\nHowever, that issue is solvable. For example, a popular question among automation engineers is which selectors are the best. The common answer is\nid or\nclass, rather than\nXPath, which could fail. Let me bust this myth and explain how to render automation frameworks reliable.\nChoosing\nid for selectors has a caveat: the value must be unique for the document, which means that it doesn’t work in the case of multiple identical UI components, such as the\n<input> element. As a resolution, our automation group at Cloudinary opted to identify locators with an attribute called\ndata-test by leveraging standard data-* attributes. Instead of just picking the least risky attribute that exists, we added\ndata-test to the application code. Not only do searches for the web element then become stable, developers are also free to change IDs and class names.\nAdditionally, as a rule, front-end developers add logic or styling with IDs or classes. Leveraging a unique attribute creates a convention that distinctly separates development and QA, leading to transparency and clarity.\nHere’s another example:\nClass names don’t work here because the styling libraries, which handle scoping, automatically generate the classes. Hence, classes are not a reliable source, and the component is not unique in the DOM.\nHowever, adding the automation attribute\ndata-test to the component leaves the UI intact, enabling QA engineers to build a stable and consistent selector.\nSome of you wondered about the performance of having data attributes act as selectors. Assuringly, the lookup time between class and data attributes is usually the same.\nTo recap, if planned and executed correctly, E2E UI tests can be sound, efficient, and flexible. Front-end developers will be at liberty to tweak the DOM with no need for the QA automation team to make corresponding adjustments, saving time for everyone. Bottom line: this process makes it easier to look for the right selector.\nPart 2 of this series will bust another myth: “Automating E2E is time-consuming.” Stay tuned.", "pred_label": "__label__POS", "pred_score_pos": 0.6141273379325867}
{"content": "Imagine your life without hot water. Tough, right? But it's easy to overlook the machinery heating that water until you discover that it's no longer working. If you're in search of a brand-new water heater for your home or business, choose the veteran heating specialists at Custom Aire Inc in Bensalem, Pennsylvania.\nServing clients throughout Southeastern Pennsylvania, including Philadelphia, Newtown, Doylestown, Blue Bell and several other surrounding communities, Custom Aire sells a wide range of water heaters from some of the most notable brands in the industry. Our extensive selection includes various water heater styles, and thanks to the rapid evolution of heating tech over the past several years, you'll discover an array of products that deliver energy-efficient performance. Reach out to our heating specialists, and we'll help you choose a water heater that perfectly suits your unique needs.\nHere's a brief rundown of the various types of water heaters available to Pennsylvania residents through Custom Aire: Storage tank water heaters:This common option employs an insulated storage tank, where hot water is stored until it's needed. Certain models are powered by electricity, while others require fuel, such as propane or natural gas. Tankless water heaters:Often selected as an energy-efficient alternative to storage tank systems, tankless water heaters provide heat on demand by passing water through their heated inner coils. Hybrid water heaters:Hybrid water heaters, also known as heat pump water heaters (HPWHs), feature both an electric storage tank and a heat pump. Many of them are designed with integrated efficiency options, marking them as a popular choice among home and business owners seeking to minimize energy usage.\nFrom tankless water heater installation to 24/7 emergency repairs and beyond, Custom Aire offers a wide range of professional heating services to residents of the Bensalem, PA area. To learn more about our available water heaters, contact us online or by phone at 215-638-1800.", "pred_label": "__label__POS", "pred_score_pos": 0.8017901182174683}
{"content": "Article content\nLet’s face it; our brains have it in for us. We produce up to 50,000 thoughts a day and 70% to 80% of those are negative. This translates into 40,000 negative thoughts a day that need managing and filtering — no small task for any person or entrepreneur. Based on these numbers, I have had at least 14.5 million negative thoughts since I launched Countlan but thankfully, I have a few coping mechanisms to prevent me from giving up or breaking down.\nIn addition to building a valuable product, an inventive marketing strategy, a strategic pricing plan and a sound distribution network, there is a psychological component to launching a startup. Even the most confident individuals fall prey to negative, judgmental, irrational, fear-based thoughts that challenge their actions and poke holes in their plans.\ntap here to see other videos from our team.\nTake heed young bootstrappers! Negative thinking need not be your demise; rather, garnering a few tactics can help you plow through the lowest days.", "pred_label": "__label__POS", "pred_score_pos": 0.761826753616333}
{"content": "Boosting lifetime of power components in multilevel inverters is a major aim to enhance the total system reliability and performance. This paper presents a space vector pulse width modulation (SVPWM) strategy for lifetime prolongation of thermally-overloaded power devices in multilevel inverters. When a thermal overloading is detected in one of the power devices, the proposed algorithm is applied to relieve the overloaded device and therefore preventing dangerous circumstances such as open-or short-circuit faults. The proposed methodology relies on using the redundancy property between the switching states in multilevel inverters to continuously evaluate the junction temperature of the thermally-overloaded power devices for all the possible switching sequences, then it identifies the optimal relieving switching sequence. The proposed methodology is valid for both/either of the power switching devices and/or DC-link capacitors. The proposed strategy is simple, and does not require any additional hardware. Furthermore, it does not deteriorate the output power. Accordingly, lifetime and reliability of multilevel inverters have been enhanced considerably. The proposed methodology has been designed and validated by simulation and experimental prototyping of a three-level T-type inverter system to investigate its feasibility and effectiveness.", "pred_label": "__label__POS", "pred_score_pos": 0.6428784132003784}
{"content": "Abstract\nA functional promoter variant of the gene encoding the MET receptor tyrosine kinase alters SP1 and SUB1 transcription factor binding, and is associated with autism spectrum disorder (ASD). Recent analyses of postmortem cerebral cortex from ASD patients revealed altered expression of MET protein and three transcripts encoding proteins that regulate MET signaling, hepatocyte growth factor (HGF), urokinase plasminogen activator receptor (PLAUR) and plasminogen activator inhibitor-1 (SERPINE1). To address potential risk conferred by multiple genes in the MET signaling pathway, we screened all exons and 50 promoter regions for variants in the five genes encoding proteins that regulate MET expression and activity. Identified variants were genotyped in 664 families (2,712 individuals including 1,228 with ASD) and 312 unrelated controls. Replicating our initial findings, family-based association test (FBAT) analyses demonstrated that the MET promoter variant rs1858830 C allele was associated with ASD in 101 new families (P50.033). Two other genes in the MET signaling pathway also may confer risk. A haplotype of the SERPINE1 gene exhibited significant association. In addition, the PLAUR promoter variant rs344781 T allele was associated with ASD by both FBAT (P50.006) and case-control analyses (P50.007). The PLAUR promoter rs344781 relative risk was 1.93 (95% confidence interval [CI]: 1.12-3.31) for genotype TT and 2.42 (95% CI: 1.38-4.25) for genotype CT compared to genotype CC. Gene-gene interaction analyses suggested a significant interaction between MET and PLAUR. These data further support our hypothesis that genetic susceptibility impacting multiple components of the MET signaling pathway contributes to ASD risk.\nKeywords Association Brain Cerebral cortex Genetic Plasminogen Plaur Serpine1 Upar ASJC Scopus subject areas Neuroscience(all) Clinical Neurology Genetics(clinical) Medicine(all)", "pred_label": "__label__POS", "pred_score_pos": 0.7038726806640625}
{"content": "At Judge Amy Coney Barret’s recent confirmation hearing for a seat on the U.S. Supreme Court, she stated that the 2nd Amendment grants individuals the right to bear arms for self-defense. But her statement is false. Anyone familiar with the actual text of this amendment and its purpose, as defined by both its prefatory clause and the framers’ intent articulated in the Federalist papers, knows (or should know) that it does not grant individuals a constitutional right to bear or own arms for self-defense. For well over two centuries the Supreme Court never decided that the 2nd Amendment granted individuals such a right, and there is no indication that the Constitution’s framers ever intended to enshrine the common-law right of self-defense in that amendment or elsewhere in our Constitution. The commonly held, but false belief by Judge Barrett that individuals have a constitutional right to bear arms for self-defense is an example of what Plato referred as a “noble lie,” a belief that, though untrue, is propagated and perpetuated to sustain public accord by inducing citizens to accept as true and legitimate. This “noble lie” has been sustained by both pro-gun politicians using fear mongering to uphold this country’s gun culture and by propaganda from the NRA for its own self-interests and for corporate profits of gun manufacturers. Former Supreme Court Chief Justice Warren Burger said, the 2nd Amendment “…has been the subject of one of the biggest pieces of fraud, I repeat the word, fraud, on the American […]", "pred_label": "__label__POS", "pred_score_pos": 0.6219631433486938}
{"content": "Interviews were previously conducted with 72 heroin-addicted female street prostitutes who spread HIV by sharing injection paraphernalia and engaging in unprotected sex with multiple male customers. Most were willing to enroll in free methadone maintenance if made available. Forty-one female addict-prostitutes subsequently entered free methadone maintenance. Twenty-five remained in treatment after one year. Their personal income from prostitution and other crime was reduced 58%; income from legal sources increased 86%. Total urinalyses positive for non-prescribed drugs decreased from 80% on admission to 51%. This pilot study validates the attraction of free methadone maintenance and concomitant reduction of illegal drug use and prostitution, two predictors of HIV infection. However, close supervision and effective counseling and rehabilitative services provided by better trained staff are required for successful outcomes among addict-prostitutes in methadone maintenance.", "pred_label": "__label__POS", "pred_score_pos": 0.9781604409217834}
{"content": "Ah, summer. Do you love it as much as I do? Hot dogs, roller coasters, ice cream, backyard pools and sprinklers...these are what come to mind when I think of summer. I wonder what my children will recall of their childhood summers. Will they think fondly of the long drives in the van to visit far-flung family and friends? Will they think of the awe-inspiring sunset behind the mountains? Will it be the evenings spent chasing fireflies in the backyard with the neighbors?\nAs a financial planner, I talk with people far too often who are \"too busy\" to enjoy the fruits of their labors. My goal is to help people reach their goals, which are rarely about having a certain amount of money in the bank. The goals I hear are to spend time doing the things they love with the people they love.\nWhat do you think of? What does \"summer\" mean to you? Have you done any of those things yet this year? As adults without small children in the house, it can be easy to overlook these pleasures, and be \"too busy\" for them now. However, you're never too old for an ice cream cone, or for a spin on the carousel.\nI hope you'll accept a summer challenge: pick your favorite memory, pick up the nearest grandchild or close friend, and go \"do\" summer. Don't let it go by without enjoying it!", "pred_label": "__label__POS", "pred_score_pos": 0.6193652153015137}
{"content": "While Eurobodalla Council is moving ahead to build a new 1000m2 gymnasium at the Batemans Bay Mackay Park leisure centre the gym industry is taking a financial hammering across the State and the country as strict Covid rules are applied. Eurobodalla Council, from the outset, was advised that if the Batemans Bay Swimming Centre was upgraded to include a gym, indoor heated pool and allied health services, these elements would likely be supported by local sporting clubs.Initially Council looked to have a 480m2 gymnasium that was projected to return $200,000 per year if leased ($2,000 per week) however the projected costs to have the facility was in the order of $350,000 ( a net loss of $150,000 per year) Council promoted in their business plan to Grant authorities that they predicted 20,000 per year to come through the gym turnstiles. This equates to 54 people per day. Possibly swayed by \"bigger is better\" the councillors voted to have the gymnasium extended to 1000m2 in the hope it might attract a larger rental. With gymnasiums across the region, inclusive of the Batemans Bay area, struggling under COVID rules, it appears speculation at best by Eurobodalla Council that their decision to add another gymnasium space to the mix and enter the real estate market competing with other property owners to sway their current lessees to move to the pool area is not such a smart move. Especially in light of their gambling with ratepayers money on a complex that is already $15m over the original budget without a sod being turned. Under the present\nrules Gyms must have a COVID-19 Safety Hygiene Marshal present at all times the gym is open, and be registered as a COVID Safe business.\nThis applies to gyms that are indoors and open to members of the public.\nIf a gym is not open to members of the public, such as a gym in a residential premises (e.g. a home or an apartment building), or in a hotel or workplace, these requirements do not apply.\nA gym does not include a dance, yoga, pilates, gymnastics or martial arts studio.Indoor gyms must assign one staff member as a\nCOVID-19 Safe Hygiene Marshal who will be in distinctive clothing (such as a shirt or badge) and responsible for ensuring all aspects of the COVID-19 Safety Plan are being adhered to including overseeing social distancing, cleaning and ensuring the accuracy of record keeping. The identified Safety Marshal/s must always be present whilst the gym is operational, including gyms that operate 24 hours a day.Ensure the number of people in a facility does not exceed one person per 4 square metres of space (excluding staff).\nEnsure gym or recreation classes or sport activities have no more than 20 participants, plus the instructor and any assistants, per space that complies with one participant per 4 square metres. There may be multiple classes in a room if there is sufficient space to accommodate this, and if the classes remain separate with start and end times staggered to minimise crowding. Ensure participants maintain 1.5 metres\nphysical distancewhere practical.\nEnsure any spectators comply with 1.5 metres physical distance where practical, such as through staggered seating. Household contacts are not required to distance.\nMove or block access to equipment to support 1.5 metres of physical distance between people.\nEnsure communal facilities such as showers, change rooms and lockers have strategies in place to reduce crowding and promote physical distancing.\nWhere practical, stagger the use of communal facilities. Strongly encourage visitors to shower/change at home where possible.\nReduce crowding wherever possible and promote physical distancing with markers on the floor, including where people are asked to queue.\nHave strategies in place to manage gatherings that may occur immediately outside the premises.\nUse telephone or video platforms for essential staff meetings where practical.\nReview regular business deliveries and request contactless delivery and invoicing where practical.", "pred_label": "__label__POS", "pred_score_pos": 0.8008577823638916}
{"content": "Abstract\nThe aim of this pilot study was to assess whether neurofeedback (NFB) can be useful in the treatment of impulsive behavior in long-term abstinent cocaine and heroin addicts. A single-blind sham-controlled NFB protocol was carried out to assess the effects of NFB on impulsivity in 20 (10 + 10) cocaine and heroin long-term abstinent addicts (Diagnostic and Statistical Manual of Mental Disorders [4th ed., text rev.; DSM-IV-TR]). Psychotic and neurologic diseases were excluded. Participants underwent 40 NFB sessions based on the very slow cortical potential range. Inhibitory deficits were specifically addressed through right and left prefrontal training. Clinical improvement was measured with Likert-type scales, the Hamilton Depression Rating Scale, and the State-Trait Anxiety Inventory, and impulsivity was assessed using the Barratt Impulsiveness Scale and the Continuous Performance Test. Although the results are preliminary due to the small sample size, the NFB-treated group showed a significant clinical improvement, including symptoms of anxiety and depression, with two differentiated time periods. No significant clinical improvement was found in the control group. A significant decrease in the post- versus pre-treatment measures of global impulsivity, nonplanning impulsivity, and error commission measures was found in the NFB-treated group; effect size (dKorr) in the pre-post control design was moderate. No significant change was found in the control group. Despite the limitations of this study, the results suggest that NFB is better than placebo in improving impulsivity and clinical symptoms of anxiety and depression in long-term abstinent cocaine- and heroin-dependent individuals.", "pred_label": "__label__POS", "pred_score_pos": 0.9272961020469666}
{"content": "In a letter to the editor in the Kennebec Journal/Morning Sentinel, a writer states:\n“Equally disturbing was the total lack of regard for Maine law by the investigation’s subjects. Illegal drug use, drinking and driving, drinking and hunting, driving with a loaded gun in addition to night hunting are not only illegal but dangerous behavior.”\nThis writer couldn’t agree more. However, to fully demonize and cast judgement on the “subjects” for breaking the laws of the State of Maine, while allowing a different standard for any law enforcement agency is not in the best interest of anyone and carries with it the same reasoning that such behavior by law enforcement, “are not only illegal but a dangerous behavior.” If Maine law allows law enforcement to break laws, it needs to be changed. If not, then how can one claim this behavior is “dangerous” for some but not for others. That’s known as a double standard. There can not exist double standards between the people and the government. Have we not been witness to the historic results?\nIf for no other reason, law enforcement, if it intends for the citizen-slaves to abide by state’s laws, should set the example and follow the same laws. Why are they any different from you and I?\nAs a parent, I always had the discussion with my wife, that if we intended our children to grow up with proper morals and behavior, then we must set the example for them. Where there is no leadership, the people perish.\nGranting blind deference to any government and/or its agents, believing this is somehow in the best interest of our future as free men, is the exemplification of brainwashing and propagandizing.\nIf the Maine Courts are ruling according to the written law, they have told us that the actions of undercover agents have been legal. That does not make them right. I, for one, would like to see those rules and regulations changed.", "pred_label": "__label__POS", "pred_score_pos": 0.6153417825698853}
{"content": "Quantifying the Influence of Beautiful Environments on Human Well-Being\nDoes spending time in beautiful settings boost people’s happiness? The answer to this question has long remained elusive due to a paucity of large-scale data on environmental aesthetics and individual happiness. Here, we draw on two novel datasets: first, individual happiness data from the smartphone app, Mappiness, and second, crowdsourced ratings of the “scenicness” of photographs taken across England, from the online game Scenic-Or-Not. We find that individuals are happier in more scenic locations, even when controlling for a range of factors such as the activity the individual is engaged in at the time, weather conditions and the income of local inhabitants.\nHowever, what might these beautiful places be comprised of? Is beauty in this context synonymous with nature? We extract hundreds of image features from over 200,000 Scenic-Or-Not images using the Places Convolutional Neural Network to understand the composition of beautiful places. We also find that a neural network can be trained to automatically identify scenic places, including both natural and built locations.\nTarget Audience\nData scientists, software engineers and anyone interested in the use of neural networks.", "pred_label": "__label__POS", "pred_score_pos": 0.9012154340744019}
{"content": "The Creighton Model System, or CrMS, allows you to know and understand the phases of fertility and infertility that occur in a woman’s cycle. It treats fertility as part of health and not a disease.\nWhat is the CrMS?\nIt is professional and personalized.\nIt is medically safe and morally acceptable.\nIt is easy to learn and inexpensive.\nIt is highly reliable and applicable to any stage of a woman’s reproductive life.\nIt is natural and cooperative.\nIt precisely identifies the true days of fertility and infertility.\nIt is essential to the monitoring and maintaining of a woman’s health.\nIf you are interested, you can contact Nora Ponder at noraponder@gmail.com for individualized appointments with personal instruction on use of the system. At each private follow-up, the FertilityCareTM practitioner tailors the system to your specific needs.", "pred_label": "__label__POS", "pred_score_pos": 0.6841728091239929}
{"content": "The Arts Education Partnership recently embarked on new work exploring the intersection of arts education and school choice, and what better time than National School Choice Week to provide an update on this work? Over the last several months, AEP has researched four key questions concerning the intersection of these areas:\nState Policy Takeaways\n1. What, if any, state policies exist that connect arts education and school choice?\nGenerally, states exempt charter schools from state policies that govern traditional public schools, but states vary in the exemptions they allow for charter schools. Charter school laws in 30 states specifically state that nontraditional schools are not exempt from statewide rules related to assessment, standards, teacher certification and graduation requirements. Eight of these states do not exempt charter schools from arts education requirements.\nThree states have charter school laws that allow authorizers to give preference to applications for schools with specific academic approaches or themes, innovations and comprehensive (well-rounded) learning experiences. While these laws don’t explicitly include the arts, charter schools may include the arts as an academic theme, innovation, or as part of a comprehensive or well-rounded education.\nResearch Takeaways\n2. What, if any, research exists on a link between school choice and arts education?\nFew studies exist demonstrating a link between school choice and arts education. One study suggests that of all public and private school types, charter schools have the lowest availability of arts (dance, music, theatre and visual arts) education.\nHowever, another study found that when controlling for geography, charter schools in Chicago offered significantly more music instruction than traditional schools — though both schools offered less music instruction than the national average.\nWhile research shows that charter schools are neither embracing or excluding music education, existing research concludes that these schools may consider it more of a supplemental activity. Despite varying results, all three studies identified a relationship between the size of the school and the likelihood of offering arts/music instruction.\nAccountability Takeaways\n3. Which, if any, states include arts education in their accountability system for K-12?\nEleven states and the District of Columbia include the arts as a part of their current or future accountability systems. While some states specifically measure participation in the arts, others measure participation in the arts as a part of a well-rounded education or include the arts as options in the postsecondary and career readiness components of their accountability systems.\nOf the states including arts education or a well-rounded education as an accountability metric, nine measure access (i.e., student enrollment) and one measures student performance (i.e., students earning passing scores).\nBudget Takeaways\n4. Which, if any, states have provisions and/or specific line items for arts education in their budget and/or K-12 funding formula?\nStates use three different funding pathways states to support arts education: discretionary funds, funding formulas and resource allocation models. There are at least 10 states with department of education appropriations for specific schools, grants or programs for arts education. One state provides an additional weight for each student participating in arts education in the public school funding formula; and two states distribute funds based on the number of positions or other resources, rather than on a per-student basis.\nAEP also launched a new page on the website dedicated to school choice and the arts, where you can read the full responses and access future resources as they become available.\nWhat’s Next?\nAEP will continue to closely explore the intersection of school choice and the arts — including if and how states, schools and/or districts implement related policies — with plans to share more findings in the spring. Stay tuned for future work, and, as always, please reach out if you have specific state-level policy questions related to the arts and school choice.", "pred_label": "__label__POS", "pred_score_pos": 0.6647908687591553}
{"content": "Abstract : Pulses present nutritional advantages for human health, and also contribute to food security and environmental sustainability. Despite these beneficial properties, the consumption of pulses in France has decreased over the past century. This study explores the representation of pulses among French non-vegetarian consumers, using both an indirect approach, with scenarios evoking real-life situations, and a direct approach, with an online questionnaire.\nFor the indirect approach, based on six different scenarios, the 120 participants composed dishes by selecting three food images out of the twenty provided. One week later, for the direct approach, the same participants completed a questionnaire, with ten questions about food products, using the same images.\nResults showed that spontaneous selection of pulses was low for all dish-composition situations, coherent with the low consumption of pulses declared in the questionnaire. Among possible barriers to pulse consumption were dislike of pulses, preparation difficulty, and perception of pulses as a food for vegetarians. Participants possessed theoretical knowledge about the benefits of pulses, but this knowledge seemed not to be applied to dish-composition situations. Results also highlighted the complementarity of these two methods, providing deeper understanding of consumer food habits in relation to pulses. Based on these findings, several levers are proposed to increase pulse consumption: improving familiarity with pulses, using the context of consumption, formulating trendy and innovative products, and promoting pulses as a “food for all”.", "pred_label": "__label__POS", "pred_score_pos": 0.7238680124282837}
{"content": "Title\nStudents' interpretation and application of feedback in a first-year English composition course\nDate of Completion\nJanuary 2007\nKeywords\nEducation, Adult and Continuing|Education, Teacher Training|Education, Curriculum and Instruction\nDegree\nPh.D.\nAbstract\nCollege graduates who communicate their thoughts and reasoning through concise, clear, and organized writing are on a fast track to succeed in today's knowledge-based society. Despite the crucial role that writing plays in the development of an individual's literacy and thinking skills in the US, the skill has largely been undervalued in high school and college. Feedback is one of the activities that students use to refine their written messages. However, instructors do not always have an understanding of how students make sense of the feedback they receive and the decisions they make to interpret and apply it in their work. This study focused on how students perceived, interpreted, and applied feedback in a First-Year Writing Composition Course at college level.^ The theoretical rationale for this study synthesized empirical and theoretical research from a spectrum of fields. Specifically, Complex Systems Theory provided a framework to understand the nature of feedback within the environment it takes place. Experiential Learning Theory provided an account of the individual experience with feedback.^ The design of this study followed a generic qualitative research methodology. Data was collected from nine students and their instructor in a face-to-face writing composition course at a large public university in the Northeastern United States. Primary data collection strategies included interview and questionnaire. Data was analyzed following the constant comparative method. Trustworthiness was established using member checking, peer debriefing, journaling, and audit trail.^ Seven themes were identified and classified into two main categories: feedback attributes and individual use of feedback. Findings suggested that students who were strategic users of feedback displayed an array of self-regulation strategies and formulated analogies to frame their interpretation of feedback messages, compared to less strategic users. The outcome of this process influenced how students applied feedback.^ Effective feedback users were characterized by their active and strategic approach. Recommendations include strategies that promote students' active use of feedback and its impact on the development of their writing skills. ^\nRecommended Citation\nOrgnero Schiaffino, Maria Carolina, \"Students' interpretation and application of feedback in a first-year English composition course\" (2007).\nDoctoral Dissertations. AAI3270954. https://opencommons.uconn.edu/dissertations/AAI3270954", "pred_label": "__label__POS", "pred_score_pos": 0.8143744468688965}
{"content": "Stress is a state of physiological or psychological strain caused by adverse stimuli; responses to stress include activation of the sympathetic nervous system, glucocorticoid secretion and emotional behaviors. Prostaglandin E(2) (PGE(2)), acting through its four receptor subtypes (EP1, EP2, EP3 and EP4), is involved in these stress responses. Studies of EP-selective drugs and mice lacking specific EPs have identified the neuronal pathways regulated by PGE(2). In animals with febrile illnesses, PGE(2) acts on neurons expressing EP3 in the preoptic hypothalamus. In illness-induced activation of the hypothalamic-pituitary-adrenal axis, EP1 and EP3 regulate distinct neuronal pathways that converge at the paraventricular hypothalamus. During psychological stress, EP1 suppresses impulsive behaviors via the midbrain dopaminergic systems. PGE(2) promotes illness-induced memory impairment, yet also supports hippocampus-dependent memory formation and synaptic plasticity via EP2 in physiological conditions. In response to illness, PGE(2) is synthesized by enzymes induced in various cell types inside and outside the brain, whereas constitutively expressed enzymes in neurons and/or microglia synthesize PGE(2) in response to psychological stress. Dependent on the type of stress stimuli, PGE(2) released from different cell types activates distinct EP receptors, which mobilize multiple neuronal pathways, resulting in stress responses.", "pred_label": "__label__POS", "pred_score_pos": 0.5370160341262817}
{"content": "In early 2020 Aberdeen surveyed 405 customer experience (CX) leaders around the world, across different industries, and within companies of all sizes. The survey revealed that 78% of companies are not satisfied with their ability to use customer data to achieve their objectives. When asked why they struggle using CX data, firms cited insufficient data. Ironically, the same survey revealed that one out of two businesses use at least 10 channels (e.g., web, email, social media, phone) in their CX activities. While companies have a wealth of insights at their disposal, outdated technologies and lagging processes hinder use of data in CX programs. In fact, the second top challenge cited by respondents was poor data quality or, in other words, the data available not being relevant or timely for employees to use in their activities.\nThis thought-provoking knowledge brief from Aberdeen demonstrates how building a unified view of customer and CX data across all sources can transform your results.", "pred_label": "__label__POS", "pred_score_pos": 0.9889957308769226}
{"content": "Hydrogen sulfide — a gas that smells like rotten eggs — can be insidious in its lethality. Its odor will be unmistakeable to its victim. But the gas can quickly numb the sense of smell, leading to the belief that the threat has passed. Unconsciousness and death can follow. “Unfortunately, if you come in contact […]", "pred_label": "__label__POS", "pred_score_pos": 0.8674500584602356}
{"content": "Blood formation, or haematopoiesis, originates from haematopoietic stem cells (HSCs), whose functions and maintenance are regulated in both cell- and cell non-autonomous ways. The surroundings of HSCs in the bone marrow create a specific niche or microenvironment where HSCs nest that allows them to retain their unique characteristics and respond rapidly to external stimuli. Ageing is accompanied by reduced regenerative capacity of the organism affecting all systems, due to the progressive decline of stem cell functions. This includes blood and HSCs, which contributes to age-related haematological disorders, anaemia, and immunosenescence, among others. Furthermore, chronological ageing is characterised by myeloid and platelet HSC skewing, inflammageing, and expanded clonal haematopoiesis, which may be the result of the accumulation of preleukaemic lesions in HSCs. Intriguingly, haematological malignancies such as acute myeloid leukaemia have a high incidence among elderly patients, yet not all individuals with clonal haematopoiesis develop leukaemias. Here, we discuss recent work on these aspects, their potential underlying molecular mechanisms, and the first cues linking age-related changes in the HSC niche to poor HSC maintenance. Future work is needed for a better understanding of haematopoiesis during ageing. This field may open new avenues for HSC rejuvenation and therapeutic strategies in the elderly.\nThis item's license is: Attribution 4.0 International", "pred_label": "__label__POS", "pred_score_pos": 0.9915869832038879}
{"content": "Over the last eight years mobility has been an increasing problem for Dawn as she has both multiple sclerosis and ankylosing spondylitis; she is now largely reliant on a wheelchair.\nShe spent her career as an Anaesthetic Theatre Sister and thrived on patient interaction. Early retirement resulted in a loss of purpose, low self-esteem and a feeling that she was not contributing to society anymore. She appeared outwardly confident and positive but in private she experienced less positive emotions such as loneliness, isolation and self-doubt.\nShe had always found flying scary; an anxiety which spoilt many overseas holidays. A chance meeting with an FSDP scholar planted the seed that a scholarship could help her overcome her fear.\n“I cannot begin to describe the gratitude and honour I feel for having had this opportunity. It is more than just learning to fly. It is about realising the potential in humans that are reeling from an injury, an illness or struggling through life.”", "pred_label": "__label__POS", "pred_score_pos": 0.5084217190742493}
{"content": "The System is Broken\nBefore the Great Depression, communities took pride in supporting those who faced poverty, suffered mental illness, and were hurting. Today, we have plenty of resources available, but the current system has placed roadblocks that present challenges to providing genuine care to those who seek help.\nWe see a trend with homelessness. According to Prosperity Now, 40% of Pennsylvanians are\nONE PAYCHECK AWAY from facing homelessness. 59% of Americans are ONE PAYCHECK AWAY from becoming homeless. Of the 40% in Pennsylvania, 350 Individuals and families are deemed homeless in the Wyoming Valley region. The 350 who live in poverty face challenges every day to survive. This fight-or-flight mentality causes poor decisions that persuade the publics’ perception of these individuals. Those who face homelessness are labeled as “drug users”, “animals”, and “dirty”, along with other derogatory characteristics. Those labels may hold in some cases, but the facts that led to these poor decisions are not considered.\nHomelessness is not the result of one individual choice, but rather the failure of a system driving our modern society. Individuals who face homelessness have a difficult time navigating the social service system. When we see an issue, we are good as a society to throw money at the problem with no real solution. The proper resources are not provided to the agencies whose job is to serve and support the vulnerable population. Some systematic issues are as follows:\nContinuing struggles in housing with limited affordable units and rising rents. Those related to housing factors, including eviction and vulnerability, due to living in crowded or unaffordable housing. Income-related issues including low income, unemployment, precarious employment, and limited income opportunities, due to lack of education and skills Lack of supports and services, including those geared towards addressing such problems as ill-health, mental illness, substance abuse, and social isolation from family and friends. Finally, we expect to pull the homeless into a shelter and then place them right into an apartment. This is considered a ‘win’ in the eyes of the pubic but is genuinely a loss to the individual. The system lacks the follow-up, the support, and the teaching of life skills to maintain stability.\nKeystone Mission is committed to working on addressing the current system that is broken. Providing outreach, like our Agape Team, which sends out our Life Coaches to help navigate that system of social services is one way we address this. Life Coaches can connect the homeless to the right resources to help them with their specific needs. The next step for Keystone Mission is to provide emergency shelter that offers a place to sleep, food in their belly, and a shower to keep clean. Rest and restoration stop the ‘fight or flight’ system they were living and helps them make rational decisions. Finally, move them into transitional housing center that transforms their lives, by learning those skills they need to survive. Through job training, budgeting, learning personal hygiene skills, and connection to resources in the community, the individual is transformed at the pace they set. Finally, we do this with the secret ingredient, LOVE. With love, for a person who has never had that experience, a transformation sparks in their life which was not seen before.\n→ GET INVOLVED Become a financial partner with Keystone Mission! Visit KeystoneMission.org/go/Donate and contribute ONE TIME or on a MONTHLY basis. Join our mailing list! E-mail Communications@KeystoneMission.org or call (570) 871–4795 ext. 400 and speak with Ryan. If you send an e-mail, place JOIN MAILING in your subject line. Include your Address, Phone, and E-mail in the body of the e-mail. Volunteer at Keystone Mission! E-mail Volunteer@KeystoneMission.org or call (570) 871–4795 ext. 408 and speak with Matthew.", "pred_label": "__label__POS", "pred_score_pos": 0.5469793081283569}
{"content": "Peer Support\nPeer support is where individuals in similar circumstances give each other practical and emotional support to help each other deal with and resolve challenging situations.\nThe Money Advice Service has undertaken a multi-stage research project to understand whether this type of support could help over-indebted people resolve their financial difficulties, and to explore how it could increase engagement with debt advice.\nThe documents available on this page report the findings from this research and include:", "pred_label": "__label__POS", "pred_score_pos": 0.7271049618721008}
{"content": "Nascate has developed a series of strict and rigorous that ensure data accuracy and reliability. Our end-to-end testing and interrogation process ensures the validity of all internal calculations and reduces rework and reprocessing, while increasing the velocity between initial access and use.\nThis comprehensive regime- refined over the past 20 years across multiple payers, lines of business, and geographies- serves as the standard for all claims database submission and quality assurance.\nWhat We Do:\nComprehensive, end-to-end testing:\nPre-Processing Upon data receipt, a suite of tests and checks are run that concentrate on: Clinical Completeness, Population Rates, Referential Integrity. In-Line Nascate utilizes numerous in-line checks during and after each metric and measure calculation. This ensures the outcomes are in line with established thresholds prior to moving on. Post-Processing When processing is complete, a QA team (Data Operations, Data Quality, and data content experts) further analyzes and reviews the database. This ensures that the process (and the hundreds of checks used to get to this point) produces a dataset that meets quality expectations and is fit for purpose, prior to being released.\nThis layered protocol is synergistic and combines individual tests, the most appropriate order of these test series, and the validation of final outputs.\nWhy It’s Important:\nData increasingly drives decision-making. Before it can be transmitted for analysis, it must undergo a variety of changes and processes, leaving plenty of room for error. Nascate has integrated years of experience, across a diverse mix of data sources, into our advanced QA protocol. This process provides cross-sectional and time series integrity and assures the information at hand is reliable and accurate.", "pred_label": "__label__POS", "pred_score_pos": 0.8439985513687134}
{"content": "If someone accuses you of sexual misconduct on a college campus, you will quickly learn about Title IX and how these accusations could affect your future. The consequences of this type of violation can be severe and impact your education, personal life, and future career. Working with a Fairfax Title IX lawyer may be the most effective way to combat the accusations against you.\nAllegations of sexual misconduct on campus can lead to both administrative and criminal proceedings. In both areas, you likely may benefit from the advocacy and guidance that a seasoned student defense attorney could provide. Avoid or minimize the risk of life-altering ramifications by contacting legal counsel right away.\nAll institutions of higher education that receive federal funding, whether public or private, must comply with Title IX. Since most colleges and universities receive federal financial aid for their students, most of these institutions are subject to this law. Issues covered under this law include any accusations of sexual misconduct, harassment, stalking, or rape that occurs during a university activity or on campus.\nIf schools fail to follow these guidelines, they risk losing their federal funding. As a result, all schools have adopted strict policies and procedures for handling these allegations. For example, every school must have an appointed Title IX coordinator to process and investigate complaints that arise on campus.\nSome cases may result in simultaneous criminal court and school administrative proceedings. However, individuals should not expect the same legal rights and protections in their administrative hearings that they would have in criminal court proceedings. Although school administrative processes vary from one school to the next, they often share some essential characteristics.\nFor example, the constitution guarantees various rights for individuals who are accused of crimes under state or federal law. They have the right to counsel, the right to remain silent, and the right to a jury of their peers. Similarly, the prosecution has the burden of proving a criminal defendant’s guilt beyond a reasonable doubt.\nIn contrast, Title IX proceedings offer no right to counsel to individuals accused of sexual misconduct. Even if the individuals do hire independent legal counsel, they often cannot participate in the process. Unlike in criminal proceedings, accused persons likely must prove that they did not commit the actions alleged by the complainant, even though they typically cannot confront their accusers or cross-examine witnesses. An experienced lawyer in Fairfax could help an accused student by explaining their rights in a Title IX case.\nIn criminal sex crime cases, individuals may face incarceration, probation, community service hours, fines, and mandatory sex offender registration. In a Title IX proceeding, the penalties are much different but can be equally, if not more, severe. For example, if a panel of university officials find it more likely than not that a student committed sexual assault, they could face:\nThese consequences can be devastating for students as they are attempting to finish their education and pursue a career. They may become ineligible for some jobs altogether and miss out on crucial internship opportunities. Without the assistance of an experienced Title IX attorney in Fairfax, they also run the risk of losing scholarships, being passed over for jobs, and becoming ineligible for other opportunities.\nAllegations of sexual misconduct or other similar accusations can be stressful, scary, and highly detrimental to your future. Since these administrative investigations and proceedings often move quickly, you should protect yourself by contacting a Fairfax Title IX lawyer as soon as you learn of the accusations against you. Otherwise, you risk the opportunity to safeguard your rights and defend yourself as effectively as possible.\nGetting legal advice in this situation could be critical to a positive outcome in your case. Without legal counsel, you may find yourself facing severe sanctions that you did not anticipate.\nDo not send us confidential information related to you or your company until you speak with one of our attorneys and get authorization to send that information to us.", "pred_label": "__label__POS", "pred_score_pos": 0.996401846408844}
{"content": "This week marked a milestone for the Committee on World Food Security (CFS). For the first time since its reform, it recognized the role of livestock in addressing malnutrition, sustainable agriculture and climate change.\nAhead of the CFS43, SIANI spoke with Delia Grace—a veterinary epidemiologist at the International Livestock Research Institute (ILRI) and a member of the HLPE livestock project team—about the so-called omnivore’s dilemma, the critical issues in livestock production around the world and a vision for policy-makers who will be implementing the HLPE’s recommendations.", "pred_label": "__label__POS", "pred_score_pos": 0.9255315661430359}
{"content": "dc.description.abstract This study explored teacher’s perceptions towards the implementation of the ten\noutcomes of High Quality Physical Education (HQPE), whether any gender issues\noccur during delivery Physical Education (PE) and identify what potential barriers\nteachers face when delivering PE.\nThe study identified six key themes: aims and values of PE, delivery of PE, extracurricular\nprogramme, lifelong participation, barriers of delivering PE and potential\nsolutions. The findings indicated a pedagogical difference between male and female\nPE teacher’s perceptions of HQPE.\nIt indicated that the male teachers produced a high level of skill performance within\ntheir extra-curricular programme, and used their PE lessons and fitness clubs to\nenhance competitiveness. It found that female teachers value the importance of\ninclusion in their lessons, and separate PE and extra-curricular as two different\nprogrammes. This suggests that, the male teachers should adapt their teaching to\nensure inclusion of all pupils, and not just the skill and competitive element. en_US", "pred_label": "__label__POS", "pred_score_pos": 0.994271457195282}
{"content": "Texas Pipe Details 36-inch (914.4-mm) gas line 1,440 PSI (99.28bar) Maximum Operating Pressure 70ºF (21.1ºC) pipe temperature 95ºF (35ºC) ambient temperature Summary 36-inch (914.4-mm) high-pressure gas line was corroded and pitted CSNRI trained technicians completed the installation in 2.5 hours No welding was required No shutdown required\nAn inspection on a 36-inch (914.4-mm) natural gas pipeline in Northwest Texas revealed significant corrosion and pitting around a girth weld. The line, designed for 1,440 psi (99.28 bar) maximum operating pressure, would need to remain in service while the repair was carried out. This meant that the product selected would have to be installed without introducing hot work.\nHaving used composite solutions in the past, the owner looked to CSNRI for a repair. After evaluating the damage to the line, experts at CSNRI suggested using the BlackDiamond® carbon-fiber wrap.\nEngineered to provide strength that enables line restoration to maximum operating pressure (MOP) without shutting down, BlackDiamond® has a long and successful track record for rehabilitating and restoring damaged pipelines to their original operational strength.\nThe system comprises three components: a solid epoxy primer, bi-directionally woven carbon-fiber material, and polymeric epoxy resin.\nThe team of technicians received training immediately prior to the installation. To carry out the repair, they used filler putty in all the defected areas on the pipeline and on the entire girth weld bead to ensure a smooth transition for the fabric. Once the putty was in place, primer was mixed and poured over the entire area.\nThen the carbon-fiber fabric was wetted and wrapped around a 2-inch (50.8-mm) OD tube to help keep tension on it while it was being installed on the pipe. The team applied 6 layers, centered over the weld cap. This design, using wider fabric, expedited installation and greatly reduced the number of layers needed to restore the line to MOP.\nThe repair was completed in approximately 2.5 hours and was fully cured in 8 hours. This approach returned the line to safety, delivering a quick, reliable repair that did not require the line to be taken out of service.", "pred_label": "__label__POS", "pred_score_pos": 0.7759257555007935}
{"content": "Tesla’s vehicle sales have picked back up in China last March following a slow February. The electric automaker’s registrations of its most affordable sedan, the Model 3, spiked 450% in March compared to the prior month, according to LMC Automotive, a United Kingdom-based research company.\nAccording to LMC, Tesla’s registration numbers rose to 12,709 in March. This figure stands in stark contrast to February, where only 2,314 Teslas were registered in China. The spike in numbers could be due to the Chinese government’s lift on COVID-19 quarantine measures. China was, for a considerable amount of time, the leader in reported cases of the coronavirus.\nHowever, Wuhan, widely considered as the epicenter of the outbreak, has reopened for business, along with many other Chinese populated cities. Tesla’s store in Wuhan reopened on March 30 after a two-month closure.\nAlthough Tesla stores and public facilities were closed for an extended period following the outbreak of the virus, the company took extensive measures to continue offering top-quality customer service to those who were interested in purchasing an electric vehicle.\nAfter implementing a series of measures like home deliveries, unlimited Supercharging, and webcam-based customer service to make life easier for those affected by the virus in China, Tesla has rebounded from a slow start of the year.\nOn the contrary, the automotive industry sank 43.4% in March as a whole in China as the pandemic continues to affect many industries across the globe,\nReuters reported. Tesla’s approach in assisting customers amidst the chaos may have contributed to the company’s growth despite the general slowdown in the economy.\nChina has fully embraced the growing electric vehicle market. Recently, government officials announced the country would be extending subsidies for “new energy vehicles,” which are classified as any vehicle with plug-in capabilities to receive power. The subsidies are valid for another two years and were announced alongside a new plan to limit the amount of diesel emissions from trucks within large cities.\nThis move could entice consumers who are in the market to buy a new vehicle to purchase sustainable forms of transportation. As Tesla begins to roll out more configurations of its Model 3 in China, the car should start appealing to a bigger audience. The Model 3’s Long Range variant, which offers a WLTP-estimated 404 miles of range, for example, could appeal to families who love road trips.\nIt is evident that Giga Shanghai’s increased production rates, alongside the demand for EVs in the country, undoubtedly helped Tesla achieve its deliveries for the first quarter of 2020. Despite China’s automotive market seemingly falling as a whole, Tesla’s performance is spelling opposite trends as the company continues to grow in the largest car market in the world.", "pred_label": "__label__POS", "pred_score_pos": 0.6635268926620483}
{"content": "By Taylor Hoogsteden\nDuring my sophomore spring of college, I experienced some health issues. As a result, I spent a lot of time visiting doctors, and was physically unable to partake in many social events. However, the one thing that kept my mind off of how bad I felt was my classwork. So, that’s what I did, in full force. Thus, while my sophomore spring was, admittedly, a challenging semester, it did serve as a friendly GPA booster, and I was thankful for this one silver lining amid an otherwise difficult time.\nI have been reflecting on my sophomore spring a lot recently, as it taught me two valuable lessons: how to find silver linings during uncertain times, and how, sometimes, a loss can result in a gain. I have applied these lessons to numerous situations I have encountered since my sophomore spring, including the situation we now face. I would like to note that—as the coronavirus outbreak has resulted in immense suffering, economic setback, and global anxiety—I do not believe any silver linings from the outbreak can even come close to compensating for the devastation that has occurred. However, I do believe that, moving forward, it is important to remember that not everything in the world is bad right now. As such, I encourage you to keep an eye out for silver linings where possible, and to hold onto any ones you might find.\nSo here’s to the good in the world, what little of it there may be; may it last, and may it grow.\nInstagram:\n@tayloravas", "pred_label": "__label__POS", "pred_score_pos": 0.9717180728912354}
{"content": "Gila Trout Oncorhynchus gilae, and Apache Trout Oncorhynchus apache are critically threatened species that can be found in various streams of the Southwest. The general public is often unaware that these species exist due to many factors including a dissociation of fish and desert environments and limited availability of high quality underwater and surface footage of Arizona streams. Surface and underwater videography was utilized to create an educational video on Gila and Apache trout from Mount Graham streams to be displayed at a Coronado National Forest visitor center and other locations. We captured high definition quality footage with low cost equipment with the intention of enabling natural resource managers to produce similar conservation videos easily in the future. To evaluate what aspects make a conservation video most effective, the footage was shown in a public space. By analyzing which images people viewed the most, we were able to understand how we might produce more engaging presentations. Macro images, contrasting colors, texture, and movement held audience attention the longest. These results allowed us to draw conclusions about which factors and characteristics of the film contributed to optimal audience engagement. Well-designed videos will better acquaint people with species that are not commonly seen, thus aiding in their conservation. Videos were produced for display for the U.S. Forest Service, Coronado District.", "pred_label": "__label__POS", "pred_score_pos": 0.5714442133903503}
{"content": "Highlighting the Magnitude of Work Motivation and Teamwork in Developing and Exploiting Human Capital: An Autoethnographic Study\nDoshi, Rahul (2010)\nAbstract\nThis research aims to emphasize the need and importance of work motivation and teamwork in the management and development of human capital. Employees form the backbone of companies and motivating them rightly can ensure success for any organization. In this research, I look to explore these boundaries by reflecting on some past incidents specifically on motivation and teamwork. By using autoethnography as a source of data collection, I am better able to relate and identify the need for personalized motivation. The findings prove to contradict as well as complement the literature review, inevitably contributing to the need for managers to understand the significance of motivating their staff.\nActions (Archive Staff Only)", "pred_label": "__label__POS", "pred_score_pos": 0.9948040843009949}
{"content": "Regional ministers seek ways to facilitate ASEAN trade\nThursday, 2020-06-04 17:41:03\nNDO/VNA - Economic ministers from ASEAN member nations convened an online meeting on June 4 to implement instructions from ASEAN leaders made at the Special ASEAN Summit on COVID-19 on April 14.\nTran Tuan Anh, Minister of Industry and Trade of Vietnam, which holds the ASEAN Chairmanship 2020, chaired the meeting.\nThe ministers approved the Hanoi Action Plan, which aims to enhance economic cooperation within the bloc and connect supply chains amid the changing circumstances in the region caused by the COVID-19 pandemic.\nThe action plan was built on the basis of a joint statement from ASEAN economic ministers, which was proposed by Vietnam and adopted at the ASEAN Economic Ministers Retreat in March.\nIt includes concrete measures to reboot ASEAN’s economy, such as maintaining commitments to market opening to ensure food security and enhancing the capacity for recovery and sustainability in regional supply chains.\nApart from avoiding new and unnecessary non-tariff measures, the bloc will also build a platform to facilitate regional trade and promote and support supply chain connectivity.\nIt will also optimise technologies and digital commerce to assist enterprises, especially micro-small- and medium-sized enterprises (MSMEs).\nThe approval of the action plan demonstrates the role of the ASEAN Community in responding and adapting to COVID-19 as well as Vietnam’s ASEAN Chairmanship in 2020.\nThe ministers also looked into joint statements issued by business advisory councils, including the ASEAN Business Advisory Council.", "pred_label": "__label__POS", "pred_score_pos": 0.519787073135376}
{"content": "Our team is well-versed in delivering complex laboratories that require a strong attention to detail, high technical knowledge and intricate programming. We are capable of providing laboratories under Design & Construct, Minor Works, Construct Only and Construction Management contracts. We have delivered works across the Education and Health sectors for educational, research and medical purposes.\nGeneral works consist of the demolition of an existing teaching/laboratory space, including the removal of all services, followed by refurbishment and/or fitout. This often includes the installation of new equipment, services, mechanical works, and life safety systems that comply with the laboratory’s specifications.\nWe have delivered Physical Containment (PC) Certified laboratories as well as ISO Clean laboratories, which require ISO clean rooms and extreme care during the construction process. Over the years we have also delivered Dry Electronics, Wet Chemical, Electrochemical, Functional Coating Corrosion Science, Cell Culture Research, IVF Clinic, Chemistry and Physics Laboratories.\nWe have completed laboratory upgrades and refurbishments at the following institutions;\nRMIT University; La Trobe University; University of Melbourne; Victoria University; Southern Cross University; University of Wollongong; University of Newcastle; University of Sydney; Macquarie University; University of Technology Sydney; University of New South Wales (UNSW); St Vincent’s Hospital; Reckitt Benckiser; Westmead Dental Hospital; IVF Auchenflower and; HCF Dental Centre.\nNotably, we have completed over 20 highly complex PC1, PC2, ISO5, ISO6, ISO7 and ISO8 laboratories at UNSW (regarded as one of Australia’s leading research universities) in the past 10 years. We have also completed laboratories in the Medical Centre at UNSW, including a Tissue Culture Lab which is currently under construction.\nOur team understands the sensitivities required when operating within live environments, ensuring the project does not compromise any ongoing experiments in surrounding labs. Our vast expertise in delivering laboratories gives our team the ability to effectively manage challenges that arise throughout the construction process, including long lead times on lab equipment. An important aspect of a laboratory project that is often overlooked until it is too late is the commissioning stage. This is why we assign a dedicated team to proactively manage all required commissioning through the use of a Commissioning Management Plan. This plan is submitted to all stakeholders on the first day of the project and discussed at each PCG to ensure all requirements are captured well in advance.", "pred_label": "__label__POS", "pred_score_pos": 0.9184643626213074}
{"content": "In 2016, definitions of sepsis and septic shock were updated to focus on organ dysfunction rather than systemic inflammatory response as the identifying trait.\nThis article aims to compare and evaluate the effectiveness of systemic inflammatory response syndrome (SIRS) and quick Sequential Organ Failure Assessment (qSOFA) in detecting sepsis in emergency department (ED) patients. A systematic search of the literature was undertaken using four databases. A total of 307 articles was identified. After the selection process, 13 articles met the inclusion criteria for the review.\nFive themes emerged from the meta-analysis: SIRS; qSOFA; timeliness and simplicity; sensitivity versus specificity; and adding lacate. SIRS offered users greater sensitivity when assessing for sepsis. However, qSOFA is a simple bedside tool with greater specificity, which does not require any blood test results. The author created a new qSOFA screening tool, which incorporated the use of point-of-care serum lactate measurement. He found that qSOFA outperforms SIRS as an ED sepsis screening tool with its strengths of efficacy, efficiency and ease. It was also found to differentiate better between uncomplicated infection and sepsis, which can commonly cause trigger fatigue in EDs.\nEmergency Nurse.\ndoi: 10.7748/en.2019.e1939\nThis article has been subject to external double-blind peer review and has been checked for plagiarism using automated software\nNone declared\nFeist B (2019) Screening for sepsis: SIRS or qSOFA? A literature review. Emergency Nurse. doi: 10.7748/en.2019.e1939\nPublished online: 15 October 2019\nAlternatively, you can purchase access to this article for the next seven days. Buy now", "pred_label": "__label__POS", "pred_score_pos": 0.5293118357658386}
{"content": "Many of the following sources are publicly available to anyone. Some are from a list at Princeton University Library, which maintains a comprehensive annotated list of data available to its students and faculty.\nAsk yourself - Who has to compile this information? Who needs this information?\nThen consider the time-frame and the geography needed.\nThe U.S. government, or state governments and universities (public and private) conduct research. Many times, the raw data from this research is available (but not always). It\ntypically would be free, but there are exceptions.\nOrganizations and companies also conduct research. This\ntypically would be a charge, but there are exceptions.\nNote that there is likely a delay in accessing data after it is compiled. From a private publisher, it could be due to an \"embargo\" (paying clients get exclusive access for a time period). From a government agency, it could be due to the extensive number-crunching, or to staffing levels.\nTIPS:\nContact regional offices of federal agencies.\nContact state headquarters offices of Georgia (or other state) agencies", "pred_label": "__label__POS", "pred_score_pos": 0.8596448302268982}
{"content": "Commercial Real Estate Law in Georgia\nIn Chatham County, Georgia, \"commercial real estate\" is any type of land or building which is used for a business, as opposed to residential, purpose.\nCommercial real estate in Chatham County, Georgia is regulated by laws which differ significantly from state and local laws that apply to residential real estate.\nPeople who buy and rent residential unites have a greater deal of legal protections not available to buyers of commercial property.\nThese include implied warranties of habitability, rent control, and covenants of use and quiet enjoyment, among many others. Of course, the most basic protections, such as prohibiting the seller from actively concealing defects, apply to both.\nCommon Commercial Real Estate Law Issues in Chatham County, Georgia\nFinancing: Some small businesses in Chatham County, Georgia find it necessary, at some point, to purchase a piece of real estate, for various reasons. However, most owners of small to medium-sized businesses can't afford to make a real estate purchase up front, with the cash they have on hand. Simply put, very few people have hundreds of thousands of dollars just sitting in the bank. One solution to this is a mortgage, which is similar to most other types of secured loans: a bank lends you money, and you put up some piece of property as collateral, so the bank has some security in the event of default. With a mortgage, however, the property being purchased with the loan also secures the loan, allowing the bank to foreclose on it in case the buyer defaults.\nConcealment of Defects: Sellers and lessors of commercial real estate are under a duty to disclose any defects in the property which might impact the buyer's decision to purchase it, such as water damage, mold, or other structural problems. These defects are quite common, and the buyer has a right to know about them. If the seller doesn't disclose these defects, where they exist, the buyer can sue for any harm this causes.\nDuty to Inspect: While buyers of real estate have some significant protections with respect to defects, they also have some obligations. Before finalizing a purchase, buyers are expected to undertake a reasonable inspection of the property, usually by using a licensed building inspector. If the buyer fails to conduct an inspection, they usually won't be able to successfully sue, if defects are discovered after the purchase.\nEncumbrances: Encumbrances are defects of a different type: rather than physical defects, they are defects of title. In Chatham County, Georgia, an encumbrance is an interest in a piece of real estate held by a third party, such as covenants or easements. An easement is a right held by someone to use the property of someone else for a certain purpose. For example, a person might have an easement on the land of another person, allowing them to cross the land to access a public road.\nCan a Chatham County, Georgia Attorney Help?\nThese issues are sometimes complex, and almost always very important. Therefore, it's essential to seek the assistance of a Chatham County, Georgia real estate attorney if you have any dealings in this area.", "pred_label": "__label__POS", "pred_score_pos": 0.5701920390129089}
{"content": "Identification of a Novel Virulence Factor in Campylobacter jejuni: Characterization, Pathogenesis and Immunity of Cj1534c AuthorTheoret, James Issue Date2009 Committee ChairJoens, Lynn A.\nMetadataShow full item record PublisherThe University of Arizona. RightsCopyright © is held by the author. Digital access to this material is made possible by the University Libraries, University of Arizona. Further transmission, reproduction or presentation (such as public display or performance) of protected items is prohibited except with permission of the author. AbstractInfection with Campylobacter jejuni is one of the leading causes of bacterial gastroenteritis, causing an estimated 2.1 million cases annually. Although infections with C. jejuni resolve naturally, over 13,000 hospitalizations and 100 deaths are attributed to this organism. Despite these alarming numbers, relatively little is known about C. jejuni pathogenesis, when compared to other enteric pathogens. This dissertation outlines the identification and characterization of a novel virulence factor in C. jejuni, the protein expressed by the Cj1534c gene. Using microarray and RT real time PCR, Cj1534c was found to be greater than 10 fold over expressed in both swine and poultry. Employing immunoelectron microscopy, we determined that at least a subset of the protein is surface localized. Based on the surface localization and up regulation in poultry, colonization studies were performed. Results demonstrate a significant reduction in colonization by a Cj1534c deficient mutant as compared to wild type. In vitro binding assays using both biotic and abiotic surfaces indicate this protein is involved with attachment to surfaces, as well as the invasion of cultured epithelial cells. In vitro findings were confirmed in vivo using swine, with the Cj1534c mutant being highly attenuated as compared to wild type strains. Additionally, the Cj1534c protein was tested for its potential as a vaccine in poultry. Studies demonstrated that Cj1534c recombinantly expressed in a Salmonella expression vector partially protected chickens, reducing cecal colonization three logs as compared to wild type. Taken together, this data demonstrates a major role of Cj1534c in both chicken cecal colonization and infection of swine. Typetext\nElectronic Dissertation\nDegree NamePh.D. Degree Leveldoctoral Degree ProgramMicrobiology\nGraduate College", "pred_label": "__label__POS", "pred_score_pos": 0.9726040959358215}
{"content": "New York City is participating in a pilot program for a unique, zero-waste initiative. Loop, a new platform from a coalition of major consumer product companies, is hoping to reduce waste and dispose of disposable packaging. Your favorite brands of over 300 products—from ice cream to shampoo—will soon be available in reusable containers.\nInstead of tossing your empty, stainless steel Häagen-Dazs container into the trash, you’ll toss it into your personal reuse bin. It will then be picked up and delivered to a sterilization and renewal facility so it can be refilled and sold to someone else. Each product’s reusable container has been designed to be used 100 or more times.\nCompanies like PepsiCo, Procter & Gamble, Nestlé, Unilever, and more are behind Loop and eager to reduce their impact on the plastic waste crisis.", "pred_label": "__label__POS", "pred_score_pos": 0.675337553024292}
{"content": "Identity and Access Governance is a niche technology that has gained strong grounds. Owing to the regulatory environment, many businesses are required to set up right checks for their employee’s usage of corporate data. This is in addition to attending to operational maintenance, administration IAM Technology and technical contingencies that require the attention of Administrative IT. IdM is a highly specialized domain, IT departments’ stakeholders are often stuck at a dead-end due to technical deficiencies in IdM setup. This impacts monitoring and maintaining overall technical / IT infrastructure.\nAvancer’s IAM Consulting Services helps organizations in designing, implementation, deployment, and maintenance of an integrated identity management system setup. Since such systems are highly customized depending on business requirements, we help organizations in getting standardized access management across platforms for users, devices, applications, and business processes. We also extend requisite support to establish physical security points through Multi-Factor Authentication (MFA) that includes biometric, smart-card and badge readers. We collaborate with enterprises to address the need to monitor operational changes on an on-going basis to pave way for smooth functioning of business processes.\nIn terms of Support Services, businesses can collaborate with Avancer in following ways:\nSetup a comprehensive portfolio of strategically established solutions in Identity and Access Governance space.\nEstablish a structured protocol-driven approach that ties with an organization’s identity management life-cycle from user onboarding to exit.\nAn efficient, cost-effective and optimized identity management processes that fall in line with existing government and industry regulations.", "pred_label": "__label__POS", "pred_score_pos": 0.7998674511909485}
{"content": "Posted by Allie Wright\nThe British Dental Association (BDA) has stated that there are a wide range of challenges facing those dental professionals operating in Scotland.\nIt was noted by the body that the release of two reports published by the NHS Information Centre highlight some of the issues facing the industry north of the border.\nDr Robert Donald, the chair of the BDA’s Scottish Dental Practice Committee, described the current circumstances for dentists in Scotland as “challenging”.\nHe said: “Recent years have seen a number of constructive initiatives, including Childsmile and the General Dental Practice Allowance, that the profession feels are making a positive difference in the fight against the oral health inequalities.”\nIt was noted by Dr Donald that while dentists recognise the pressures facing the public purse at the present time, oral health is something that must be invested in over time.\nDr Donald took the BDA role after its previous incumbent Dr Robert Kinloch was elected to the BDA’s new Principal Executive Committee.", "pred_label": "__label__POS", "pred_score_pos": 0.5885311365127563}
{"content": "The second bug, meanwhile, led police to, in some instances, associate a device with the wrong cellphone tower. As a result, they may have linked innocent people to crime scenes.\nFollowing an audit, authorities determined they will need to review 10,700 court cases dating back to 2012. The review will start with cases that are already before the country's courts, in addition to ones where individuals are serving prison sentences. The country has also ordered that cell location data not be allowed as evidence in any criminal cases for two months while it continues to investigate the issue.\nAt the moment, it's unclear whether the situation in Denmark will force justice systems in other countries to reevaluate how they use cellphone data to try criminal cases. Unless they licensed their tools from a third-party, the bugs Danish Police discovered were likely limited to their system. That said, it may add fuel to ongoing discussions on how authorities use cellphone data to pursue criminal cases in other parts of the world. In the US, for instance, police use of IMSI catchers — devices that mimic a cellphone tower, thereby allowing authorities to collect a wealth of sensitive data — has been a controversial topic over the past few years.", "pred_label": "__label__POS", "pred_score_pos": 0.9730443358421326}
{"content": "Divorce can be a grueling experience for both spouses. When children are involved, the stakes are even higher. But, often, the system seems to be stacked against divorcing fathers.\nWhile divorce often leads to a better quality of life and a brighter future, many courts favor moms over dads regarding child custody and parenting time. Working with a family law attorney focused on fathers’ rights can help you prepare for the road ahead.\nMost common obstacles for divorced dads\nWhile many states have taken a more balanced approach to custody and co-parenting, gender bias remains strong in the Nebraska court system. That often leads to challenges in these areas:\nFamily court system:Men are often relegated as the traditional “breadwinner,” while women are seen as the primary or custodial parent. While some fathers quit their jobs to care for their kids, many divorced dads feel shame asking for alimony and child support. Flawed child support system:Since fathers are less likely to gain sole custody of their children, they are more likely to be ordered to pay child support. While the goal is to provide an adequate level of care for their child, the system can be especially harsh on low-income fathers. Increased health risks:Divorce is one of the most stressful experiences for any person. Research shows men’s mortality rates increase after divorce and they are more at risk for developing high blood pressure, depression, heart disease, cancer, substance abuse and suicide. Lack of emotional support:Men are less likely to seek much-needed mental help from friends or family members after divorce, and researchers say that translates into having more difficulty recovering. Many times, couples shared the same social circle, and those friendships go away. Acknowledge the challenges\nPerhaps the most critical takeaway for dads is recognizing that these adversities exist and to take pro-active measures to keep them from getting a foothold in their future. Working with a lawyer who understands a father’s rights when it comes to divorce, custody and support issues can be a crucial step in setting a positive foundation for your new life.", "pred_label": "__label__POS", "pred_score_pos": 0.8190078139305115}
{"content": "HICC: Humoral Immune Correlates for COVID19 HICC: Humoral Immune Correlates for COVID-19 Defining protective responses and critical readouts for clinical trials of vaccines and therapeutics\nSARS-CoV-2 is an emerging virus with very high infectivity, responsible for the ongoing global pandemic of COVID-19. To maximise our success in protecting people against this disease, we work to understand and develop highly accurate tests to identify when a person has developed a protective immune response versus a COVID-19 disease response.\nThis is critical for guiding clinic and public health decisions and developing safe, effective vaccines.", "pred_label": "__label__POS", "pred_score_pos": 0.5694098472595215}
{"content": "Only by the blood of Jesus can we receive God's forgiveness through His redemptive plan. God is love and He loves us. However, He did not die for us simply because He loves us, but because He needed to in order to forgive us. Just because God loves everyone does not mean that all have received the forgiveness that God has provided. Forgiveness only comes when we accept God's full payment for sin. Until we accept Christ as our Lord and Saviour we will not experience God's forgiveness and be reconciled to Him. This is the key to our freedom.\nIn the garden Satan came in the form of a serpent to Adam and Eve convincing them that God was holding out on them. This lie caused them to sin as they disobeyed God and obeyed the serpent by eating the fruit from the forbidden tree. Their intimate relationship with God was destroyed. They immediately hid and separated themselves from the presence of God because now they were naked and afraid of Him. God asked them where they were, wanting them to realize what they had done. God was holding them responsible for their actions. Many people today are afraid of God because they have sinned by listening to the voice of Lucifer.\nGod in His holiness killed two animals in front of Adam and Eve. He wanted them to see each animal die and its blood poured out for them to let them know that this was the requirement for sin. He then made coats for them before putting them out of the garden. He showed them by the shedding of blood that only He can deal with and take away sin. They were responsible for the animal that was sacrificed for their sin. They needed to remember that it was an animal's blood that was poured out to cover their sin. Genesis 4:1-5 tells us that in the course of time that Abel brought a firstborn lamb as an offering to the Lord and He accepted it. However, Cain's offering of wheat, which was the work of his hands, God did not accept. This reveals that man cannot be forgiven by works.\nGod has always had a plan of redemption from the very beginning, even from the foundations of the world (Ephesians 1:4). In the Spirit, the Lamb was already slain before Adam sinned. The enemy thought He destroyed God's plan for mankind, but he did not. As Hebrew 10:4-5 says, Christ came into the world because it was not possible for the blood of bulls and goats to take away sin. It only covered the sin. God gave Himself (Jesus) a body to offer for sin because He was the perfect sacrifice for sin. His shed blood washes the sin away and removes the penalty and the wrath of God.\nSin is a direct attack against God's holiness. Sin cannot come near Him. God's holiness and righteousness was being satisfied on the cross. He was dealing with all of man’s ungodliness. God's divine wrath against sin came upon Christ. Jesus became the curse for us. Only Jesus could bear the punishment and wrath of God in His body as He was both God and man. No other person but God Himself could be the sinless one to bear His wrath against sin.\nGod has always had the answer for sin and provided it through the cross. He loved us so much that He was willing to take upon Himself the punishment for our sin at Calvary. Otherwise we would be forever separated from Him. The cross is the divine miracle of God for us. We are forgiven. Jesus said He counted it all joy enduring the cross for all of us (Hebrew 12:2). Jesus death was the only reason He came to earth. He came to pay the penalty for sin. That's why Jesus said “Do this in remembrance of me” when we take communion. God prepared all of this so that He could forgive you and me. So, when we accept the powerful work of the cross and receive His forgiveness; we must be willing to forgive those who have hurt us by slander, offense or abuse. If we do not forgive, our Heavenly Father cannot forgive us as it says in Matthew 6:14-15. May we do what Ephesians 4:32 tells us and be kind to one another, forgiving each other, as God in Christ forgave us.\n- Pastor Carol McLean", "pred_label": "__label__POS", "pred_score_pos": 0.5799516439437866}
{"content": "NASA's Mars Science Laboratory (MSL) probe launched from its Cape Canaveral platform on Nov. 26, 2011, bound for the red planet. The spacecraft's onboard rover, Curiosity, entered the Martian atmosphere on Aug. 5, 2012, (EDT) and landed in an ancient equatorial depression known as Gale Crater. From there, the rover traveled out to explore the alien landscape, collect samples, and take pictures of the extraterrestrial scenery.\nOver the course of its first year on Mars, the rover has covered a considerable amount of ground and enabled a greater understanding of the Martian surface. Curiosity's engineering achievements—to date—include the following three milestones:\n\"Has Mars ever been capable of supporting life?\" Curiosity definitively answered that question when it examined an area known as Yellowknife Bay in 2012 and 2013. The rover gathered data over the course of approximately six months, during which it also sent over 70,000 photographs to NASA researchers on Earth. Substrate analyses revealed clay deposits, indicating that water had previously been present at the site in the form of an ancient—and pH-neutral—lake. Initially, members of the NASA team controlled Curiosity remotely. However, on Aug. 27, 2013, the rover began using autonomous navigation for the very first time. This precisely engineered feature—also known as autonav—allows Curiosity to calculate a safe path over the Martian surface using data extracted from images taken during a drive. On Aug. 17, 2013, Curiosity took several strikingly clear photographs of the Phobos solar eclipse. The rover's advanced engineering includes a mast camera known as the MastCam system, which has a 1600 x 1200 pixel imaging capacity, 720p video capability, and a ten-frame-per-second continuous shooting mode. When the eclipse occurred, Phobos's irregular outline became a clearly visible silhouette against the sun: Curiosity's solar eclipse pictures were the sharpest ever taken from the Martian surface.\nMany innovative concepts have already emerged from the data gathered by Curiosity. Professor Steven Benner, for example, recently proposed a new theory about the evolution of life on Earth. According to Benner's hypothesis, the conditions at Yellowknife Bay may have led to RNA formation via a prebiotic chemical process. If true, life potentially started as RNA on Mars and hitched an interplanetary ride to Earth aboard a Martian meteorite before evolving into DNA.\nOther data, including a series of solar radiation measurements taken on the journey from Earth to Mars, will likely prove beneficial to engineers involved in the proposed Mars One mission. If successful, the privately funded mission—which is currently planned for 2023—will take four people on a one-way expedition to the planet. Engineers will need to take solar radiation levels into consideration as they design and build a spaceship capable of making the journey.\nThe latest rover expedition has shed new light—literally and figuratively—on the surface of Mars. As well as identifying ancient water sources, Curiosity has captured crisp imagery and navigated the terrain all by itself. The innumerable engineering marvels aboard the rover have enabled its continued exploration and may one day help human beings create a manned spaceship suitable for interplanetary travel—and a personal trip to Mars.\n(Photo courtesy of Victor Habbick / Freedigitalphotos.net)", "pred_label": "__label__POS", "pred_score_pos": 0.7187372446060181}
{"content": "America's wetlands, which provide critical wildlife habitat as well as pollution and flood control, are drained, filled and polluted at an alarming rate. This July 2002 report from NRDC and the National Wildlife Federation looks at the potentially damaging consequences of a January 2001 Supreme Court decision regarding \"isolated wetlands,\" and illustrates the vital role these areas play in ecosystems across the United States.", "pred_label": "__label__POS", "pred_score_pos": 0.9824520349502563}
{"content": "Alternatively, your doctor might start by spraying your throat with a local anesthetic. Your doctor will then pass a tapered dilating instrument through your mouth and guide it into the esophagus. Your doctor may also use x-rays during the esophageal dilation procedure.\nContinue Learning about Ear, Nose and Throat\nImportant: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.", "pred_label": "__label__POS", "pred_score_pos": 0.9999847412109375}
{"content": "I am frequently asked about how to “snake proof” a home. To answer this question, it is important to understand snake behaviour around homes and where I have personally found them when attending emergency snake call outs.\nMy favourite snake to catch is the red bellied black snake. These snakes are very beautiful and typically have a great temperament. The first time I encountered a red bellied black snake was as a child and my fascination continued until this day.\nThere are three types of copperhead snakes in Australia. The one you should commonly find in Melbourne and surrounding areas is the Lowland Copperhead snake. This snake is not typically known compared to other snakes such as the tiger or eastern brown, howe...\nMost of the venomous snake call outs I receive in Melbourne are where someone has spotted a tiger snake in their home or backyard. This snake (depending on which scientific journal you read) is the 5th most venomous snake on land in the entire world. They a...", "pred_label": "__label__POS", "pred_score_pos": 0.6513543128967285}
{"content": "By Jennifer Burek Pierce\nLibrary providers to teens may still aspire to 2 primary pursuits: to interact youth via significant and beautiful responses to their leisure and informational wishes, whereas aiding sturdy developmental results. How are these people who paintings in libraries, who might even see youngsters in basic terms sporadically and for brief sessions, imagined to paintings successfully with them? --From the IntroductionHow can we most sensible achieve our teenager buyers? younger grownup librarians and others who serve them always attempt to raised comprehend this often-unpredictable audience.In this insightful consultant, Jennifer Burek Pierce offers a desirable examine this present day s teenager during the lens of neurological, mental and academic study. placing this examine within the context of library prone, she demanding situations librarians to question their assumptions approximately youngster consumers and supply new solutions according to learn discovering. very like early literacy study trained library prone to youngest consumers, this provocative booklet outlines what others who paintings with teenagers have discovered from their expert actions and the way that wisdom can motivate new priorities and partnerships in formative years services.Use this learn to:?· support deal with the evidence from fiction approximately adolescent mind improvement and sexuality?· Equip employees to appreciate and sensitively engage with teens?· Foster realizing approximately kids, expertise, and multitasking?· comprise teenager pleasant prone and actions into the library", "pred_label": "__label__POS", "pred_score_pos": 0.9784636497497559}
{"content": "One hundred and nine years ago, on September 11, 1911, a dam built on Freeman Run north of the town of Austin, Potter County, PA, broke. The the ensuing flood caused significant damage to Austin and to the town of Costello further downstream. Seventy-eight people lost their lives during the disaster.\nThe concrete impoundment dam at Austin was built by the Bayless Pulp and Paper Company in 1909. Almost immediately concerns were raised about the dam’s safety. Cost saving shortcuts in the design, including a draw-off pipe with a wood cap that could not be operated when the water level rose too high, compromised the integrity of the dam. Even before it was filled with water cracks were noticed in the face of the dam. Despite warning signs and the urging of concerned individuals the Bayless Co. did nothing to sure-up the dam, and at this point in history there was no official regulation regarding dam safety in Pennsylvania. Even in the aftermath of the Johnstown Flood in 1889 (another severe dam failure disaster), the PA legislature failed to pass new safety laws or regulations. It took the Austin Dam disaster for changes to be made.\nThe ruins of the dam can be visited today at the Austin Dam Memorial Park, located approximately 20 miles southwest of the museum along Route 872.\nThese images from our archival collection (LM2018.3) document the aftermath of flood’s destruction.", "pred_label": "__label__POS", "pred_score_pos": 0.8349999189376831}
{"content": "Correctional healthcare defense is a unique form of litigation related to the delivery of medical care within the correctional setting through contracts between state, federal and local agencies and private healthcare providers.\nThe representation of these providers requires an understanding of the constitutional requirements for healthcare in correctional facilities as well as the operations of these facilities, the contractual terms for how care is delivered inside and outside of the correctional facility, the unique challenges facing medical providers in a correctional facility setting, and the management of acute and chronic medical issues. Litigation related to the correctional healthcare setting can be brought in state and federal courts and can include claims that the plaintiff’s civil rights were violated, giving rise to the potential for awards of attorney’s fees and punitive damages.\nHPS has significant experience defending providers of healthcare in correctional facilities against claims alleging wrongful death, medical negligence, and civil rights violations. These claims have included issues related to obstetrical care, hunger strikes, mental health, suicide and sudden death. Our experience allows us to vigorously defend matters of litigation as well as counsel providers of correctional healthcare regarding trends and the law to assist with planning, allocation of resources, and identification of issues to reduce the risk of future litigation.\nHPS has represented correctional healthcare clients in multiple states, including Arkansas, Colorado, Illinois, New Mexico and Wyoming.\nRELATED ATTORNEYS:", "pred_label": "__label__POS", "pred_score_pos": 0.8716588616371155}
{"content": "Negative regulators of cell death signalling pathways in cancer\nCancer is a primary cause of human death with a global economic toll of around US$1.4 trillion each year. It is estimated that about 12 million people will yearly die of cancer by 2030. Conventional cancer therapies such as chemotherapy or radiotherapy usually interrupt vital cellular events and are often associated with side-effects, tumour drug-resistance, and cancer recurrence. The main challenge in conventional therapies is that cancerous tissues evolve drug-resistance rapidly through inhibition of cell death signalling pathways such as apoptosis, ferroptosis, necroptosis, autophagy, and anoikis.\nDe-regulation of cell death principally occurs through the activation of negative regulators suppressing cell death mechanisms during oncogenesis. For instance, resistance to apoptosis is known as the hallmark of cancer leading to tumorigenesis and the development of drug-resistance. Therefore, to overcome cancer drug-resistance, it is important to deactivate the negative regulators of cell death pathways.\nWe critically discussed the current state of knowledge on targeting negative regulators of cell death pathways and evaluated the advances in clinical and pre-clinical research on biomarkers of negative regulators. It aimed to provide a comprehensive platform for designing effective combinational therapies including novel agents for reactivating cell death signalling pathways or targeting alternative resistance pathways to increase the chances for anti-tumour responses. In conclusion, understanding negative regulators of signalling pathways will help to identify potential therapeutic targets, and design diagnostic and prognostic biomarkers. Strategically “molecularly targeted therapies” are emerging through investigation of apoptotic signalling pathways. However, evidence is accumulating that non-apoptotic modes of cell death such as necroptosis and autophagy also play a significant role in inducing drug-resistance, necessitating more attention for drug discovery.\nAli Razaghi Centre for Biodiscovery and Molecular Development of Therapeutics, James Cook University,Townsville, Australia Present affiliation: Department of Laboratory Medicine, Karolinska Institute, Stockholm, Sweden PublicationNegative regulators of cell death pathways in cancer: perspective on biomarkers and targeted therapies.\nRazaghi A, Heimann K, Schaeffer P.M, Gibson S.B\nApoptosis. 2018 Feb", "pred_label": "__label__POS", "pred_score_pos": 0.7336946129798889}
{"content": "Census\nCyber and IT challenges remain as Census resumes operations\nBy Derek B. Johnson Jun 11, 2020\nThe IT systems needed to carry out the 2020 census still face numerous testing challenges and unaddressed critical cybersecurity risks, according to a new audit from the Government Accountability Office.\nThe report details how the U.S. Census Bureau, which has begun resuming its work after halting operations amid the ongoing coronavirus pandemic, faces a range of new challenges and delays caused by the spread of the virus and resulting lockdowns. Those challenges include communicating \"timely, clear and consistent\" information for continuity of operations plans to local field offices, meeting previously established targets for self-reporting households, maintaining sufficient staffing levels, monitoring ongoing risks to IT systems and managing disinformation and misinformation campaigns.\nThe bureau had announced it would resume operations at 211 area offices in all 50 states as of May 29. In advance of that, according to an GovWinIQ analysis, 99% of Commerce spending the week of May 17 (totaling $51.2 million) was dedicated to Census operations and COVID-19. Expenditures included advertising services, laptops and disinfectant supplies.\nAddressing outstanding cybersecurity weaknesses in systems expected to be used during the census are a top concern. The audit reveals that as of April 2020, the agency was still struggling to implement more than 234 unaddressed remediation plans for \"high\" and \"very high\" risk cybersecurity weaknesses in the 52 IT systems that will be used in the census.\nTesting schedules for those systems have also been impacted by the pandemic. An official said told auditors that the bureau \"was continuing to assess the risks associated with the COVID-19-related schedule changes to the implementation of IT, including the number of enumerator handheld devices expected to be available and the significant contract support required to conduct the 2020 Census.\"\nFor instance, the bureau has purchased an additional 125,000 handheld devices in anticipation of hiring more census workers, but it has not conducted testing to ensure that IT systems can handle the increased workload without degrading overall performance. The agency must also reassess its timeframes for reducing contractor-provided IT servers, storage capacity and software licenses in response to schedule delays associated with the pandemic.\nThe agency must also deal with a wave of disinformation, misinformation and conspiracy theories—often widely shared on social media—about the purpose of the census.\nEarlier this year Sen. Gary Peters (D-Mich.), ranking Democrat on the Senate Homeland Security and Governmental Affairs Committee, wrote to the Bureau and executives at Facebook, Twitter and Google, calling such campaigns \"a significant threat\" to achieving an accurate count.\n\"These private organizations are in unique positions to support the Bureau's fight against misinformation disinformation throughout the 2020 Census, including during the awareness, self-response and Nonresponse Followup phases,\" Peters wrote to U.S. Census Director Steven Dillingham in February.\nAuditors at GAO share those concerns, and urge the bureau to further strengthen internal processes while continuing to forge relationships with social media partners to remove misleading content.\nCompressed timeframes caused by the pandemic are also likely to impact the quality and processing of data used for delivering congressional apportionment and redistricting. During past counts, census operators could make up to six door-to-door visits to collect information from a non-responsive household. Amid the pandemic social distancing guidelines, such efforts \"may be less effective\" and impact the quality of data for hard-to-count populations.\nDerek B. Johnson is a former senior staff writer at FCW.", "pred_label": "__label__POS", "pred_score_pos": 0.7857440710067749}
{"content": "Abstract\nDisturbed activity patterns in cortical networks contribute to the pathophysiology of schizophrenia (SZ). Several lines of evidence implicate NMDA receptor hypofunction in SZ, and blocking NMDA receptor signaling during early neurodevelopment produces cognitive deficits in rodent models that resemble those seen in schizophrenic patients. However, the altered network dynamics underlying these cognitive impairments largely remain to be characterized, especially at the cellular level. Here, we use in vivo two-photon calcium imaging to describe pathological dynamics, occurring in parallel with cognitive dysfunction, in a developmental NMDA receptor hypofunction model. We observed increased synchrony and specific alterations in spatiotemporal activity propagation, which could be causally linked to a previously unidentified persistent bursting phenotype. This phenotype was rescued by acute treatment with the NMDA receptor co-agonist D-serine or the GABA\nB receptor agonist baclofen, which similarly rescued working memory performance. It was not reproduced by optogenetic inhibition of fast-spiking interneurons. These results provide novel insight into network-level abnormalities mediating the cognitive impairment induced by NMDA receptor hypofunction. ASJC Scopus subject areas Psychiatry and Mental health Cellular and Molecular Neuroscience Biological Psychiatry", "pred_label": "__label__POS", "pred_score_pos": 0.9426764845848083}
{"content": "Achieving Sustainable Development Goals 5 and 6: The case for gender-transformative water programmes\nAs we approach the 10-year countdown to the Sustainable Development Goals (SDGs), it is clear we are far from achieving SDG 5 on gender equality, and SDG 6 on universal access to water and sanitation. While gender equality and access to safe water and sanitation are often treated as separate issues, they are deeply linked and interdependent.\nThis paper argues that to achieve both Goals, the international community must adopt more gender-transformative approaches to water development. Improved data collection at national and sub-national levels is needed; there is also a need for increased opportunities for women’s meaningful participation in water governance. It is essential to address gendered social norms – particularly around unpaid care work.", "pred_label": "__label__POS", "pred_score_pos": 0.9994593858718872}
{"content": "This report brings together 27 indicators of human and ecosystem wellbeing using IUCN's pioneering Sustainability Assessment method. It is intended to complement Wellbeing Scores software, which allows users to explore different standards and combinations of what comprises sustainable development. The publication may provoke debate amongst forest conservationists and critics and provide them with a platform for exploring this new software.\nIncludes bibliographic references, and a computer program, Wellbeing Scores, on a cd-rom.", "pred_label": "__label__POS", "pred_score_pos": 0.9998636841773987}
{"content": "In Xenopus tadpoles, all retinal ganglion cells (RGCs) send axons contralaterally across the optic chiasm. At metamorphosis, a subpopulation of EphB-expressing RGCs in the ventrotemporal retina begin to project ipsilaterally. However, when these metamorphic RGCs are grafted into embryos, they project contralaterally, suggesting that the embryonic chiasm lacks signals that guide axons ipsilaterally. Ephrin-B is expressed discretely at the chiasm of metamorphic but not premetamorphic Xenopus. When expressed prematurely in the embryonic chiasm, ephrin-B causes precocious ipsilateral projections from the EphB-expressing RGCs. Ephrin-B is also found in the chiasm of mammals, which have ipsilateral projections, but not in the chiasm of fish and birds, which do not. These results suggest that ephrin-B/EphB interactions play a key role in the sorting of axons at the vertebrate chiasm.", "pred_label": "__label__POS", "pred_score_pos": 0.9999890923500061}
{"content": "Brain opioid peptide systems are known to play an important role in motivation, emotion, attachment behaviour, the response to stress and pain, and the control of food intake. Opioid peptides within the ventral striatum are thought to play a key role in the latter function, regulating the affective response to highly palatable, energy-dense foods such as those containing fat and sugar. It has been shown previously that stimulation of mu opiate receptors within the ventral striatum increases intake of palatable food. In the present study, we examined enkephalin peptide gene expression within the striatum in rats that had been given restricted daily access to an energy-dense, palatable liquid food, chocolate Ensure(R). Rats maintained on an ad libitum diet of rat chow and water were given 3-h access to Ensure(R) daily for two weeks. One day following the end of this period, preproenkephalin gene expression was measured with quantitative in situ hybridization. Compared with control animals, rats that had been exposed to Ensure(R) had significantly reduced enkephalin gene expression in several striatal regions including the ventral striatum (nucleus accumbens), a finding that was confirmed in a different group with Northern blot analysis. Rats fed this regimen of Ensure(R) did not differ in weight from controls. In contrast to chronic Ensure(R), acute ingestion of Ensure(R) did not appear to affect enkephalin peptide gene expression. These results suggest that repeated consumption of a highly rewarding, energy-dense food induces neuroadaptations in cognitive-motivational circuits.", "pred_label": "__label__POS", "pred_score_pos": 0.5103670358657837}
{"content": "A recent publication based on the work done by ICTS post-doctoral fellow Dr. Amit Kumar Chatterjee and faculty members Dr. Anupam Kundu and Dr. Manas Kulkarni, titled ‘Spatiotemporal spread of perturbations in a driven dissipative Duffing chain: An out-of-time-ordered correlator approach’, in the journal Physical Review E, has been selected by the Editors as the ‘Editors’ Suggestion’.\nStudy of chaotic phenomena has always been a subject of interest in the context of dynamical systems, due to its wide applications in diverse fields, starting from atmospheric sciences to technological electro-mechanical devices. However, search for proper tools, for systematic study of chaos in spatially extended classical and quantum systems, are still in progress. In this regard, to probe open (no energy conservation) classical many-body systems, the authors in this study have implemented a recently proposed classical analogue of quantum out-of-time-ordered commutators that have been extensively used to study quantum chaos. In this classical analogue, the out-of-time-ordered correlator (OTOC) has been successfully incorporated by the authors to diagnose different dynamical regimes of a chain of coupled Duffing oscillators in presence of external drive and dissipation. The OTOC provides a clear demarcation of three distinct dynamical regimes where chaos is sustained, transient, and absent. The work exhibits the significance and prospect of OTOC as a remarkable diagnostic of spatio-temporal chaos in generic classical many-body systems in presence of dissipation and drive. The present work consisting of extensive information about the degree of chaos can be of potential use in areas like encryption devices, secure communications, and signal detection to name a few.\nThe study marks a significant step forward in the area of driven-dissipative systems and was selected by the editors due to its particular interest, importance and clarity.", "pred_label": "__label__POS", "pred_score_pos": 0.9934544563293457}
{"content": "For Immediate Release July 8, 2020 Washington, D.C.- In response to the ongoing negotiations in the UN Security Council for the renewal of cross-border assistance to Syria, Dr. Mufaddal Hamadeh, SAMS President, has released the following statement:\n“We are deeply concerned by efforts to reduce the number of crossings in the cross-border mechanism, which is a vital lifeline to the 4 million civilians living in northwest Syria. At a time when the humanitarian needs are growing and the threat of COVID-19 remains, such action would be nothing short of reckless.”\n“Both border crossings in the northwest – Bab al-Hawa and Bab al-Salam – provide critical, life-saving humanitarian assistance to highly vulnerable populations. Bab al-Hawa is used to support 2.8 million people in Idlib, while Bab al-Salam is used to support 1.4 million people in Northern Aleppo. Presently, there is no proven alternative that can deliver assistance to these populations on such a large scale.”\n“We reiterate our call for both crossings in the Northwest to be renewed for 12 months. The Security Council must set aside politics and instead pass a resolution that reflects the humanitarian needs on the ground in Syria. This also includes addressing the dire humanitarian situation in northeast Syria.”\nSAMS operates 50 medical facilities in northwest Syria. Last year, we provided 2,452,082 services to 1,142,164 individuals. In 2019, SAMS delivered 238 containers to its medical facilities in northwest Syria, totaling over $12 million in medical and humanitarian assistance.\nFor media inquiries, contact SAMS Senior Media & Communications Manager Lobna Hassairi at [email protected]", "pred_label": "__label__POS", "pred_score_pos": 0.9442124366760254}
{"content": "Thank you for your question. A “leaking fallopian tube” (hydrosalpinx) occurs when the end of the tube is damaged from STIs causing pelvic inflammatory disease (PID), surgery, or adhesions (scar tissue). Hydrosalpinx occurs when the tube becomes blocked, filling with sterile fluids, which creates an enlarged tube. You may not even know you have hydrosalpinx, because you don’t always experience pelvic pain. The only sign of hydrosalpinx you may experience is infertility (inability to become pregnant), particularly if both tubes are affected. If you have a hydrosalpinx, ask your primary care provider about your making an appointment to see a gynecologist to discuss options, including laparoscopy (surgery that uses a video camera) or fertility treatment.", "pred_label": "__label__POS", "pred_score_pos": 0.9640066623687744}
{"content": "Since trade finance is lifeblood of global business, it has a positive role to play in driving sustainable practices. Here, banks can lead by example: through collaborative efforts, they can play a crucial role in encouraging a diverse network of counterparties to safeguard environmental, social and governance (ESG) principles, while also stimulating growth. So, how can “sustainable trade” be fully realized to meet these ends?\nTag:", "pred_label": "__label__POS", "pred_score_pos": 0.9999419450759888}
{"content": "As the world gets used to the new normal, businesses are gradually preparing to reopen and resume everyday work. However, after months of quarantine and remote work, it seems like a challenging task to open up offices, especially with the looming danger of a second wave of the pandemic.\nIn addition to ensuring the physical health and safety of the returning workforce, HR managers are particularly concerned about staff mental health and psychological safety. This mandates the need for policies and strategies to make employees welcome and safe in the workplace.\nStreamlined internal communication is a crucial aspect of this movement. And it can only happen with the right software and a robust company intranet that makes it easier than ever for employees to access frequent updates, information about staying well, and tools that aid their work.\nRead on to find out how an intranet can make your return to work transition smoother:\n5 Ways SharePoint Intranet Supports You While You Return To Work\nAs you make plans to ensure a smooth return to work process, it’s also important to devise contingency plans for the uncertain future ahead.\nThe following are some ways your company intranet can help your business to navigate the new normal:\nCentralized Location for Policies on Switching Back to Remote Work\nWith the increase in Covid-19 cases, the chances of a second wave of the disease are still looming. Now, you already have the policies and protocols that were created during the first wave. But it would be best if you re-evaluated their potency.\nSharePoint intranet serves as a common platform that houses all the protocols and procedures related to work-from-home in case of a second wave. Your employees can also use it to gain access to real-time official updates on Covid-19. It also allows you to create a forum where the leadership can update their employees if a second lockdown is implemented.\nKeeps Tabs On Your Employee’s Physical Well-Being\nSharePoint Intranet serves as a platform where you can keep tabs on any symptoms reported by your employees through forms. The HR then presents them with necessary isolation protocols that can be saved on the platform and be viewed from anywhere.\nThe intranet works as a centralized platform for all information on maintaining employee safety that should be available in multiple formats, including audio, video, and subtitles.\nOffers Help on Mental Health Issues\nCOVID-19 has exposed the global population to stress elements that have a massive impact on their mental health. This is why a company returning to the new normal must be vigilant about its employee’s mental health.\nThis is where the intranet helps you. It serves as the platform where you can offer information on mental health awareness and counseling services. You can also provide contact information or links to HR or occupational health workers to access them easily.\nShares the Burden of Your HR Team\nThe HR team is overburdened with devising safety protocols, overseeing the layoffs and furloughs, and implementing the SOPs at the workplace.\nWith the SharePoint intranet, you can automate HR processes and workflows that save them enough time to manage other important tasks that they could not spare time for.\nStreamlines Remote Workflow\nMost organizations continue to allow some of their workforce to work from home, but this usually means a hindrance in communication between your on-site and remote teams.\nWith the help of the SharePoint intranet, you can assess the success of your remote work strategies through your employee satisfaction levels. It also gives them complete access to all the digital tools and information they need to work from home effectively.\nIn Conclusion\nTo encourage digital transformation in your workplace, you need to leverage the power of an intranet. Getting the right intranet software helps you connect remote workers, streamlining the workflow, keep tabs on your employees’ well-being, and update them on the latest information.\nDefinity First offers Microsoft SharePoint Intranet that allows you to empower your employees with the right collaboration tools. It also keeps a heightened focus on your company’s goals, culture, values, and preferences.", "pred_label": "__label__POS", "pred_score_pos": 0.5594782829284668}
{"content": "Looming Disasters\nToo Big to Handle - Interdisciplinary Perspectives on the Question of Why Societies Ignore Looming Disasters\nSystemic risks such as climate change and pandemics, and natural disasters such as hurricanes, earthquakes and asteroids, are often too big to handle physically, but they are no longer ‘Acts of God’ and beyond human understanding and the possibility of prevention and disaster relief preparation. Indeed, in many of these areas there is much talk, less action and only paltry gains. This free to access special issue of Global Policy explores the question of when and why societies are unable to handle these looming disasters. It stems from a conference held on 9th and 10th October 2014, at the Wissenschaftskolleg in Berlin (Institute for Advanced Study, also popularly and internationally known as the WIKO), well known for its encouragement of cross-disciplinary interactions.\nIntroduction Special Issue Articles Philip Kitcher - Masking The Meaningful Andreas Glöckner - Psychology and Disaster: Why We Do Not See Looming Disasters and How Our Way of Thinking Causes Them Françoise Lavocat - Catastrophes To Come: What Can Literature Tell Us? Todd Sandler - Strategic Aspects of Difficult Global Challenges Scott Barrett - Collective Action to Avoid Catastrophe: When Countries Succeed, When They Fail, and Why Susan Rose-Ackerman - The Limits of Cost/Benefit Analysis When Disasters Loom Jonathan B. Wiener - The Tragedy of the Uncommons: On the Politics of Apocalypse Anne van Aaken - Is International Law Conducive To Preventing Looming Disasters? Janis Antonovics - The Value of Concept: Lessons from the Evolution of Antibiotic Resistance Peter Kareiva and Emma Fuller - Beyond Resilience: How to Better Prepare for the Profound Disruption of the Anthropocene", "pred_label": "__label__POS", "pred_score_pos": 0.8790807127952576}
{"content": "Abstract\nIt has been well-established that unfavorable scaling relationships between *OOH, *OH, and *O are responsible for the high overpotentials associated with oxygen electrochemistry. A number of strategies have been proposed for breaking these linear constraints for traditional electrocatalysts (e.g., metals, alloys, metal-doped carbons); such approaches have not yet been validated experimentally for heterogeneous catalysts. Development of a new class of catalysts capable of circumventing such scaling relations remains an ongoing challenge in the field. In this work, we use density functional theory (DFT) calculations to demonstrate that bimetallic porphyrin-based MOFs (PMOFs) are an ideal materials platform for rationally designing the 3-D active site environments for oxygen reduction reaction (ORR). Specifically, we show that the *OOH binding energy and the theoretical limiting potential can be optimized by appropriately tuning the transition metal active site, the oxophilic spectator, and the MOF topology. Our calculations predict theoretical limiting potentials as high as 1.07 V for Fe/Cr-PMOF-Al, which exceeds the Pt/C benchmark for 4e ORR. More broadly, by highlighting their unique characteristics, this work aims to establish bimetallic porphyrin-based MOFs as a viable materials platform for future experimental and theoretical ORR studies.", "pred_label": "__label__POS", "pred_score_pos": 0.9843026995658875}
{"content": "You might not think about cleaning your carpets and upholstery often, but maybe you should. These soft, porous surfaces collect dirt, soil and bacteria, impacting your air quality and producing odors. Luckily, TG's Carpet Cleaning & Restoration is an established carpet cleaning and upholstery cleaning company in Flagstaff, AZ.\nWe know how to efficiently extract dirt and soil without harming your belongings. Textile care is our passion and we take specific steps to handle each job correctly. That includes grooming, vacuuming, steam extracting, pH balancing and drying. We've spent decades perfecting our process.\nWho do you turn to for textile cleaning services? TG's Carpet Cleaning & Restoration has been serving Flagstaff, AZ and the rest of Northern Arizona for more than 20 years. We're family-owned and -operated, meaning that we take a special pride in our work. You can trust that you're getting thorough services performed with state-of-the-art tools and products. Once we're finished, you'll have a stunning and sanitary space again.\nSchedule upholstery, tile or carpet cleaning services with our team today.", "pred_label": "__label__POS", "pred_score_pos": 0.9144561886787415}
{"content": "The traditional wisdom of the corporate sector states that if the employees are paid higher, they would be more productive. It might be true to some extent, but modern research negates the authenticity of this statement. It is owing to the fact that personal satisfaction always stands higher as compared to financial strength.\nThere is no denying that happiness counts more weight when compared with the money. It is evident from the fact that people want to stay in such workplaces that are open to cater to them with the ultimate opportunities for happiness sharing.\nTop reasons positivism is essential for higher productivity\nA recent study has revealed that a happy workforce showed a 12% increase in their productivity while the staff that was not happy with their work environment were estimated at 10% less productive. It clearly indicates that encouraging positivism is crucial for higher productivity in the workplace.\nIt is undoubtedly the reason that many corporations in UAE and located in other parts of the world pay focus to get specialized soft skills training to encourage the employees for positivism.\nHere are given the reasons elaborating the importance of positivism for workforce productivity:\nWork-Life Balance\nMany times, employees feel the difficulty in striking a perfect balance between their personal and professional life. It is because they consider the job as a way of earning money, but the majority of them don’t enjoy their work.\nFurther, they show higher concern to their personal affairs as compared to the work. In this way, their thinking gets negative towards a balanced approach.\nThe training to encourage positivity among the employees is essential to help them considering a balance between their job responsibilities and personal activities.\nAugmented motivation\nThere is no denying that an individual with a positive attitude is more motivated as compared to the one who is pessimistic. You can well understand that a motivated individual is highly productive.\nTherefore, it is imperative to focus on grooming positivism among the workforce for better performance in their specialized fields.\nAppreciative and Inspiring leaders\nPositivity fosters the concept of self-esteem among the people who are internally enlightened to inspire others. It is something very crucial for emerging leaders.\nPrecisely speaking, a leadership that believes in appreciating others is highly helpful to achieve organizational goals. Don’t forget, every individual should show the qualities of a leader while accomplishing their tasks and activities.\nConclusion – Positivism in the Workplace\nSumming up, it is essential for people to stay positive. It is because life is not a bed of roses and every single day, employees have to deal with a lot of ups and downs in professional as well as personal life. But, with an attitude of positivism, they can deal with the routine life situation with courage and firm resolution. Ultimately, this helps them to perform better and stay highly productive.\nRemember! The negative impact of adverse circumstances cannot be denied, but it can be eliminated through rigorous motivational vibes and positivity training!", "pred_label": "__label__POS", "pred_score_pos": 0.6173696517944336}
{"content": "3/2020\nvol. 19\nabstract:\nOriginal paper\nThe effect of educational program based on the theory of planned behavior on HIV prevention skills\n1.\nSchool of Health, Guilan University of Medical Sciences, Rasht, Iran\n2.\nDepartment of Health Education and Promotion, Research Center of Health and Environment, School of Health, Guilan University of Medical Sciences, Rasht, Iran\n3.\nHealth Promotion Research Center, Zahedan University of Medical Science, Zahedan, Iran\n4.\nSocial Determinants of Health Research Center, Saveh University of Medical Sciences, Saveh, Iran\nHIV AIDS Rev 2020; 19, 3: 180-186\nOnline publish date: 2020/10/09\nIntroduction The prevalence of acquired immune deficiency syndrome (AIDS) is dramatically expanding in the world and the only way to deal with it is through health education. This study sought to determine the effect of educational intervention based on the theory of planned behavior (TPB) on AIDS preventive behaviors in nursing and midwifery students. Material and methods This was a quasi-experimental study conducted in 2016, and included 104 nursing and midwifery students from Guilan University of Medical Sciences. A questionnaire consisted of sections with demographic characteristics, awareness, behaviors, and constructs of the theory of planned behavior, and was provided to every participant. The questionnaire content validity rate was 0.8, content validity index was equal to 0.82, and Cronbach’s a coefficient test was 0.9. After collecting data in both groups, educational intervention was conducted within the framework of the theory of planned behavior in the intervention group. Data was collected before the intervention and three months later and was analyzed with SPSS statistics version 21. Results There was no significant difference between the two groups in terms of demographic variables (p > 0.05). Additionally, no significant differences were noted between the intervention and control groups before the educational intervention in terms of awareness, attitude, subjective norms, perceived behavioral control, behavioral intention, and preventive behaviors (p > 0.05). However, after the implementation of educational program, these variables significantly increased in the intervention group (p < 0.05). Conclusions The TPB was effective in teaching students in the field of AIDS prevention skills. Therefore, it is recommended to use the theory of planned behavior for human immunodeficiency virus prevention behaviors.\nkeywords:\nAIDS, education, students", "pred_label": "__label__POS", "pred_score_pos": 0.8009892702102661}
{"content": "Monday, June 15th: Simcha Barkai Value without Employment by Simcha Barkai (London Business School) and Stavros Panageas (UCLA, Anderson and NBER) [pdf]\nWhile young firms’ contribution to aggregate employment has been underwhelming over the past decades, a similar trend is not apparent in their contribution to aggregate sales and aggregate stock market capitalization. We provide evidence that the weak job creation by young firms coincided with an increase in the ratio of firm-value-to- employment and sales-to-employment for these firms. The weak job creation suggests that recent firm cohorts have faced a comparatively lower marginal product of labor (for a fixed unit of labor) compared to their predecessors, while the higher firm value-to- employment ratios suggest a higher average product of labor. Motivated by these facts, we study the implications of the arrival of “high average / low marginal” product-of- labor firms in a stylized model of dynamic firm heterogeneity, and show that the model can account for a large number of facts related to the decline in “business dynamism”. While accounting for the decline in business dynamism, the model also shows that aggregate output and productivity may remain unaffected by the decline in dynamism.", "pred_label": "__label__POS", "pred_score_pos": 0.7949936389923096}
{"content": "Summary\nLiquid crystal surfaces can undergo topographical morphing in response to external cues. These shape-shifting coatings promise a revolution in various applications, from haptic feedback in soft robotics or displays to self-cleaning solar panels. The changes in surface topography can be controlled by tailoring the molecular architecture and mechanics of the liquid crystal network. However, the nanoscopic mechanisms that drive morphological transitions remain unclear. Here, we introduce a frequency-resolved nanostrain imaging method to elucidate the emergent dynamics underlying field-induced shape-shifting. We show how surface morphing occurs in three distinct stages: (i) the molecular dipoles oscillate with the alternating field (10–100 ms), (ii) this leads to collective plasticization of the glassy network (~1 s), (iii) culminating in actuation of the topography (10–100 s). The first stage appears universal and governed by dielectric coupling. By contrast, yielding and deformation rely on a delicate balance between liquid crystal order, field properties and network viscoelasticity.", "pred_label": "__label__POS", "pred_score_pos": 0.9915910363197327}
{"content": "I define yoga as an inner peace practice to unify mind, body, and spirit. I study how African American women's #historicalwellness is recorded in memoirs and autobiographies since at least the mid-nineteenth century. This work demonstrates how Black women's self-care traditions, including meditation and yoga, are feminist-womanist acts of liberation.\nMy inner peace and wellness research began in 2013 and has been quite a journey. In my work, I highlight power brokers (redefining power through writing), self-healers on a quest for mental health, and elders in their 90s and 100s who offer guides for longevity. Rosa Parks (who lived to age 92) is a primary example of Black women's yoga history: she learned \"stretching\" from her mother, took formal classes with nieces and nephews and--in her 60s--taught yoga to communities in Detroit and Akron. As cited in a\nYoga Journal's \"Yoga 101/Wisdom feature, this healing history is also part of understanding the struggle for civil and human rights.\nAs intellectual history, memoirs unveil strategies found in IndexUS and other public health research. I argue that memoirs are mentors and elders offer tools for sustainable wellness. These practices are especially important for survivors of sexual violence, an issue which disproportionately impacts Black women. Women like Sonia Sanchez, Jana Long, and Kanika Bell write about peace as a practice. Black women's yoga history builds on their research.\n| | | Research", "pred_label": "__label__POS", "pred_score_pos": 0.8052824139595032}
{"content": "She hungered, and so she ate.\nAt first, she ate only that which was laid before her, presented as a meal. For a time, this sated her, yet as is the way with hunger and desire, she could not be sated forever. As the days and years passed the meals given to her came to bore her, and it came to be that she took no joy in them. Without joy, her hunger could not be sated.\nShe began to seek her own meals. At first, she scrounged from cabinets and cupboards, eating what she could that required no preparation. She prepackaged snacks and desserts, and fruits and vegetables, and plain bread, too impatient to form any ingredients into meals. Yet she discovered that, no matter how much she consumed, it seemed to leave an empty void within her, aching to be filled.\nTherefore, she began to craft her own meals. She learned quickly how to cook simple things that came ready-to-prepare, with instructions on how to make them into a meal. These dulled the ache of her hunger, but still, she was often left wanting more, at which time she reverted to scrounging for snacks until she worked up the drive to prepare another meal.\nWhen she realized that such simple meals were not enough, she began to learn how to truly prepare food. Studying from cookbooks and from articles she found on the internet, she studied the art of food preparation. Her meals grew not only in complexity, but in size. Soon large swaths of her life were themselves consumed by the time it took her to prepare what eventually equated to feasts for each of her meals.\nThese satisfied her more fully than any of her previous attempts. Yet, no matter how much she made herself for breakfast, by the time lunch rolled around, she had become ravenous once more. The same held true for dinner, and — because she began eating four such meals a day — supper.\nHer family and friends expressed their concerns for her. This frustrated her. She had begun to share her feasts with them, even though it deprived her of portions of her sustenance, because they had marvelled at the amount of food she produced, and the increasing quality of it. They had, for a while, raved about the excellence of her cuisine, and encouraged her to pursue becoming a professional chef.\nShe’d had no desire to do that, and she blamed the fact that she didn’t conform to their whims for the attack they launched upon her. They told her she had grown too large, and that to continue to consume so much for every meal, every day, would eventually cause her to collapse from her own weight, if no other side effect of it brought her down before then. They told her that her consumption was depleting her parents’ money, and her own, and that eventually she would run out and be unable to sustain her lifestyle.\nTheir attacks drained her, and she found that the meals she had come to covet, for they had resulted in the most fulfilled time of her life, were not enough to replace the energy her family and friends were taking from her with each blow. She wept as she ate, because each bite felt empty and fruitless, and the meals into which she poured so much of her effort no longer satisfied her.\nIn desperation, she began to devote less of herself to cooking. In fact, she abandoned it entirely, and within the span of a few days, she had gone from making extravagant meals to eating her ingredients raw. Vegetables, fish, eggs, meat, flour — it didn’t matter. She consumed it. She no longer felt she had time, between the pangs of hunger, to process the food into a more edible form.\nWhen her food ran out, she turned to her parents, who stood before her, weeping with concern. She sat upon the floor, legs splayed out before her, and the stains of food that had fallen from her mouth smeared across her girth. Her parents pleaded with her to stop and allow them to help her, but the hunger was too strong. She couldn’t listen to them. She had no strength to bear their pleading. She had only strength to consume, and so she did.\nShe reached out for her mother and took her in her hand, pulling her into her mouth. She feared at first that she would not be able to open her jaw wide enough. Her fears were unfounded. She loosened her throat and, with effort, swallowed her mother whole. Her tears as she did so were too strong to allow her the effort of chewing.\nNext came her father, who did not flee, but came forward to strike at her feebly, moaning in anger and fear. She took him in both hands. Head-first, she pushed him into her mouth, quieting his pleading and ranting. He followed her mother down her esophagus, clothes and all. Once he was gone completely, she sat in silence, contemplating what she had just done.\nShe felt full. The meal had dampened her hunger in a way that nothing before had ever accomplished. She reveled in the feeling, even while parts of her rebelled against the action she had just taken. The joy of feeling so deeply full dampened her regrets.\nShe wanted more of that joy. She wanted it to last forever. So, one by one, she called each of her remaining friends. One by one they came to her, drawn in by sweet lies of change and reinvention, which she promised for herself, if only they could come over and help her through a difficult time. One by one, she took them in her hands and swallowed them whole, so that they could join the others she had consumed before them.\nWhen she had gone down through the whole list of those who would consider responding to her, she tossed her phone away from her, disgusted, for the first time in her life, at how full her stomach felt. She couldn’t stand. She could hardly move, with the hard knot of people compacted into such a small space within her. She feared that if she shifted the wrong way, she might burst from the strain of keeping them inside.\nShe had nothing left in the world. She had eaten all the food in her house. She had eaten her family and her friends. She had only herself. Unable to move, she sat for hours in her kitchen. The pressure in her stomach remained, given her the sense that she was still physically full, but the hunger returned anyway. She had to eat. She wanted to eat, but there was nothing left, and her phone was out of reach. She couldn’t even call to have food delivered.\nShe raised her hand to her mouth and bit down. Her jaw was weak from sadness and fear and her growing hunger, but desperation lent it strength. The first bite wasn’t enough. It didn’t slice cleanly through. She had to grind her teeth together for that first, sweet release. She wept, not from pain, but from the relief of chewing, of the beauty of having something flowing down her throat once more after hours going without even water.\nBit by bit, she chewed and crunched, letting her mind relax into the rhythm that brought her euphoria. Her head grew light, and she allowed herself to believe it was from the pleasure of eating as she consumed herself. She felt her mind drifting upward, and her thoughts floating away, as everything within grew too light to be contained by a mortal vessel. Feeling lighter than she had since she first began to eat, she dispersed and faded away.", "pred_label": "__label__POS", "pred_score_pos": 0.743980348110199}
{"content": "Abstract\nOBJECTIVE. To compare stance control between children with sensory modulation disorder (SMD) and typically developing children in various visual and somatosensory conditions. METHOD. Thirty-one children participated in this study, including 17 children with SMD and 14 matched typically developing children. The Sensory Profile was used to screen for sensory modulation problems, which were further confirmed by measures of electrodermal response and the Evaluation of Sensory Processing. Stance parameters for an assessment of postural stability were obtained with a dual-axis accelerometer on the lumbar area. RESULTS. The children with SMD presented atypical sensory responses in terms of both electrophysiological and behavioral measures. The results for stance showed a greater body sway in the SMD group than in the control group (p < .05). However, the group difference was not always significant under the conditions of reliable somatosensory input and sway-referenced vision. CONCLUSION. Our findings first confirmed impaired stance control in children with SMD.\nAll Science Journal Classification (ASJC) codes Occupational Therapy", "pred_label": "__label__POS", "pred_score_pos": 0.9991640448570251}
{"content": "This image from the NASA/ESA Hubble Space Telescope shows the galaxy Messier 86. Despite its being discovered over 235 years ago by astronomer Charles Messier, the morphological classification of Messier 86 remains unclear; astronomers are still debating over whether it is elliptical or lenticular (the latter being a cross between an elliptical and spiral galaxy).\nMessier 86 is part of the Virgo Cluster of galaxies and is situated about 50 million light-years from Earth. The galaxy is moving through space remarkably quickly — its current trajectory is bringing it in our direction, back towards the center of its cluster from the far side, at the incredible speed of over 543,000 mph (874,000 kph)! Because of the speed with which it is moving through the cluster, Messier 86 is undergoing a process known as ram-pressure stripping. The resistive material filling the gaps between individual cluster galaxies is pulling at the gas and dust in Messier 86 and stripping them out as the galaxy moves, creating a long trail of hot gas that is emitting X-ray radiation.\nAstronomers are using Hubble observations such as this to study elliptical and lenticular galaxies, both of which are often found at the centers of galaxy clusters. By studying the cores of these galaxies, astronomers hope to determine details of the central structure and to analyze both the history of the galaxy and the formation of its core.\nMessier 86 is featured in Hubble’s Messier Catalog, which includes some of the most fascinating celestial objects that can be observed from Earth’s Northern Hemisphere.\nImage: ESA/Hubble & NASA, P. Cote et al.", "pred_label": "__label__POS", "pred_score_pos": 0.571677565574646}
{"content": "Key Points Two primary types of investments: Debt & Equity Perceived risk vs. real risk Understanding investor emotions\nInvesting is allocating resources, often savings, with the goal of generating an income or profit. Your life stage and financial circumstances play a significant role in your investment objectives. However, regardless of your objectives, investing boils down to two important rules; earning a return on your investment and ensuring the protection and return of your principle.\nInvesting is generally broken into two major category, debt and equity. Debt investments involve lending your money to others, a borrower, in exchange for a fee. This fee functions like rent, but it is commonly referred to as interest. The general goal with debt investments is preservation of capital and income. Debt investments include:\nsavings & money market accounts certificates of deposits (CDs) Corporate bonds government & municipal bonds Private lending Annuities\nUnlike debt investments which don’t participate in ownership, equity investments involve partial or complete ownership of an asset and offer the potential for the asset to increase in value. If the asset, such as a business is profitable, the equity investment may also provide income in the form of dividends or rental income such as from real estate. The general goal with equity investments is for the asset to increase in value, commonly referred to as growth. Equity investments include:\nStocks Mutual Funds Real Estate Real Estate Investment Trusts (REITs) commodities Businesses\nAnother factor to consider when investing is risk. Risk can be real or perceived. If you’ve ever experienced turbulence while flying on a commercial airline, the perceived risk to passengers may appear high while the real risk is low. Passengers on the Cruise ship Titanic probably had exceptionally low perceived risk but tragically faced high real risk.\nReal risk can actually be lowest when perceived risk is highest. The stock market in March of 2003 and February of 2009 had just experienced significant declines from previous highs. After experiencing substantial losses, investors were fearful that the market would continue lower. While the perceived risk was extremely high, these dates turned out to be exceptional buying opportunities and real risk was in fact low.", "pred_label": "__label__POS", "pred_score_pos": 0.9514411091804504}
{"content": "Abstract: The history and significance of Helena Rutherfurd Ely (1858-1920) and hergardens at Meadowburn Farm are relatively unknown. At the turn of the century, Elywas one of America’s most influential writers on practical gardening: her first book, AWoman’s Hardy Garden, was an extraordinary and lasting success. She was also afounding member and subsequent Vice President of the Garden Club of America.While her name has faded from common household knowledge, Ely’s gardens atMeadowburn Farm still remain, and the owners have begun to consider possibilitiesfor preserving and opening the gardens to public visitation.This study clarified the significance of Ely’s gardens, assessed the feasibilityof their preservation, and suggested applicable preservation models for the owners toconsider. Research methods relied on qualitative data gathered through site visits,historical record research, and interviews with professionals and community leaders,complemented by quantitative survey data. Results indicated that Ely’s gardens arehistorically significant as the surviving personal gardens of an influential figure inAmerican horticultural history. The characteristics of Meadowburn Farm and thesurrounding community suggest preservation efforts will capture interest andpatronage. Preserving these significant gardens will require investment of resourcesand dedicated leadership.", "pred_label": "__label__POS", "pred_score_pos": 0.9751268029212952}
{"content": "In addition to ISO 26262, which refers to functional safety of road vehicles for safety-critical E/E systems, the ISO 21448 SOTIF standard addresses the safety of the intended functionality (SOTIF) to establish a safety standard for driver assistance systems and functions for autonomous vehicles.\nSOTIF focuses on the absence of unreasonable risks due to hazards resulting from functional deficiencies of the intended functionality or due to reasonably foreseeable misuse by persons.\nIn the development of automated functions and autonomous and semi-autonomous vehicles, accurate situational awareness is critical to safety. SOTIF describes situational awareness that is derived from complex sensors and processing algorithms. Defining measures that comply with SOTIF is absolutely crucial for automotive systems of an OICA/SAE J3016-defined automation level 2 and higher.\ndSPACE offers a consultancy service to define these measures and implement them into processes, methodologies, tooling, and verification and validation criteria.\ndSPACE participates in the VDA (Verband der Automobilindustrie – German Association of the Automotive Industry) working group on establishing SOTIF as the ISO 21448 (NA 052-00-32-08-06 AK „SOTIF“) standard.", "pred_label": "__label__POS", "pred_score_pos": 0.9953486323356628}
{"content": "Navigating Through Ph.D Programmes: Experiences of Ghanaian Ph.D Graduates from Universities across the Globe (Published) This research sought to examines the experiences of Ghanaian PhD graduates from various universities across the globe. A qualitative research model was therefore designed and used to explore factors that motivated the PhD graduates to pursue their programmes, challenges they faced in the course of their study, effects of these challenges on them and how they dealt with the challenges. Purposive and convenience sampling techniques were employed to select twenty participants for the study. The theoretical focus of the study was on human capital theory. The data was analysed using thematic approach. It emerged from the study that job placement and security, the academic environment, family aspiration and expectation, personal desire to stand out to be visible and availability of scholarships were factors that motivated Ghanaian PhD graduates to pursue their programmes. The findings also revealed that Ghanaian PhD graduates lost most of their acquaintances deliberately, missed their families and social life, and had difficulty managing supervisor/student relationship, battling with theories, data management and analysis. It became obvious that as part of PhD students orientation they should be made to understand that uncertainty, doubt, disappointments are parts of the PhD experience and they should not be derailed by those conditions. Universities running PhD programmes should provide counselling centres and programmes that are tailored towards the reduction of stress factors accompanying PhD programmes.", "pred_label": "__label__POS", "pred_score_pos": 0.5138567686080933}
{"content": "Federal law makes it illegal for your employer to discriminate against you or sexually harass you, but those rights would be meaningless if your employer could retaliate against you with impunity for complaining. If you believe that anyone at your company has taken adverse actions against you for making a complaint of illegal workplace practices, the dedicated employment attorneys at Sanford Law Firm in Birmingham are ready to fight to stop the retaliation and get you compensated for any damages you may have suffered as a result.\nThe Equal Employment Opportunity (EEO) Act protects employees from sexual harassment as well as discrimination based on race, gender, disability, age, religion and certain other characteristics. The law also prohibits retaliation against employees for engaging in certain “protected activities” related to its enforcement. These include:\nRetaliation is any adverse action taken for the purpose of punishing you for engaging in protected activity, including:\nIf you suspect that your employer is retaliating against you for engaging in protected activities, our employment lawyers will review the facts of your situation and advise you if you have a legal claim.\nIf you do have a case for retaliation, we are ready to push promptly for a resolution in your favor. After investigating the facts and assembling evidence, we make a demand that the employer cease all adverse actions and compensate you for any damages suffered as a result. If your employer is unwilling to comply, we will file charges with the Equal Employment Opportunity Commission (EEOC). The standard of proof is that it is more likely than not that any adverse job action was motivated by retaliation. This can be shown by evidence of:\nWe will present the strongest case that is supported by the facts and evidence and will vigorously contest your employer’s defenses.\nRetaliation can include adverse actions taken by workers outside of management. For instance, if a woman accuses a male co-worker of sexual harassment, and he or another co-worker defames her or makes her job more difficult, that constitutes retaliation. Furthermore, if management doesn’t stop the adverse actions, it may also be liable. We are ready to bring a case against anyone in the organization who engages in retaliation or who allows it to continue.\nSanford Law Firm handles all types of claims where Alabama employees face discrimination, workplace harassment or retaliation. Please call 205-675-0726 or contact us online to schedule a meeting at our office on Richard Arrington Jr. Boulevard North in Birmingham.", "pred_label": "__label__POS", "pred_score_pos": 0.5535277128219604}
{"content": "Can I Sue After an Aggressive Driving or Road Rage Incident in Pennsylvania?\nPennsylvania is a diverse state. In the areas where major cities like Philadelphia, Harrisburg, and Pittsburgh are located the roads are often filled with a high volume of vehicles all jockeying for position and trying to reach their destination. However, if you were to head out to the more rural parts of the state, you are likely to find yourself with significantly more space to maneuver your vehicle. At night and early in the morning you may even be the only vehicle on the road. The contrast in driving culture is significant and this can lead to misunderstandings among drivers and possibly cause car crashes.\nHowever, regardless of where you perform you driving in the state, one thing never changes: All drivers must find strategies to cope with reckless and aggressive drivers. In rare occasions, circumstances may even place motorist in a position where he or she must deal with a dangerous and unpredictable road rage situation. While the terms aggressive driving and road rage are widely used in the media, they are often used interchangeably and imprecisely. However, there is a distinct difference between aggressive driving incidents and road rage incidents. Depending on the factors and circumstances present in your incident, you may have a viable personal injury or other action that can allow you to obtain compensation for the injuries, lost wages, and other damages inflicted.\nWhat is Aggressive Driving?\n“Aggressive driving” can refer to multiple types of dangerous and distracted driving issues, some of which are ticketable offenses. Acts that can be considered aggressive driving include tailgating, speeding, erratic lane changes, failure to signal, racing other vehicles, speeding to beat a traffic light, and an array of other behaviors. While some people drive aggressively as a matter of course, others tend to do so when faced with heavy volume, congestion, or traffic and a tight deadline.\nWhile Pennsylvania does not have an aggressive driving statute, the state legislature has passed a resolution that encourages drivers to engage in defensive and courteous driving behaviors. Furthermore, the legislature has stated that it intends to support all measures that would improve driving safety in the state. One of these efforts is the Pennsylvania Aggressive Driving Enforcement and Education Project (PAADEEP).\nPennsylvania Engages In Measures to Reduce & Eliminate Aggressive Driving Behaviors\nUnder the PAADEEP program, the state of Pennsylvania is divided into six Law Enforcement Liaison (LEL) districts. As its name suggests, PADEEP is intended to educate drivers about aggressive driving, how to avoid driving in this manner, and how to handle other aggressive drivers. However, education is not the only goal of this program. The project also compiles and analyzes state crash data to identify certain locations with a high prevalence of aggressive driving. These identified areas are then targeted for enforcement which typically includes high-visibility enforcement making use of police vehicles and conspicuous aggressive driving checkpoints.\nThe most recent PAADEEP aggressive driving enforcement wave occurred this past summer from July 6 to August 30th. More than 330 municipal police forces participated in enforcement actions on approximately 474 roadways. While statistics are not yet available for this most recent enforcement drive, there is information available for the 2014 enforcement wave. Last year’s aggressive driving campaign produced more than 50,000 citations for aggressive driving offenses. Of those tickets, more than 31,000 of them were for speeding.\nWhat is Road Rage and How is it Different from Aggressive Driving?\nIn contrast to aggressive driving which is a moving violation, road rage incidents occur when aggressive driving escalates into a significantly more serious altercation. The archetypical situation for a road rage incident is when a driver perceives another as driving carelessly, aggressively, or simply being in the way. This driver may become incensed and resort to a violent act to make his or her displeasure known. In some cases, the driver may use his or her vehicle as a weapon by driving at the other vehicle or the driver who has exited his or her car or truck. In other cases, the driver may stop his or her car, get out of his or her vehicle, and confront the other driver. In some cases, the driver may even produce, brandish, or use a weapon. In short, a road rage incident is more serious than an aggressive driving incident and is a criminal offense typically being prosecuted as an assault and battery. If an individual is killed due to road rage, the incident may result in vehicular homicide charges.\nCan I Sue if I Have Been Injured by an Aggressive or Enraged Driver?\nAs a starting point, you cannot typically sue someone simply for driving in a manner you do not like. In general, for an individual to bring suit several factors must be present.\nFirst, there must be a valid legal cause of action that can sustain the lawsuit. One of the most common grounds for a personal injury lawsuit motivated by a car accident is negligence. Under a negligence approach, the injured party must prove the existence of four main elements:\nInjury – In a negligence action, the presence of an injury and other damages is necessary. If there is no injury or damages, the action cannot be sustained. Furthermore, as a practical matter for all personal injury actions, there must generally be severe, life-altering injuries or the death of the victim must occur. In the case of the death of a driver, a wrongful death and survival action may also be brought. Duty – Under a negligence action the injured party must show that he or she was owed a duty by the other driver. This duty is fact-sensitive, but in the context of operating a motor vehicle, motorists owe other motorists the duty that they will drive with due care in a lawful, diligent, and reasonable manner for the circumstances present. Breach – For an individual to be held financially liable for a driver’s injuries, he or she must have breached the duty owed to his or her fellow motorists. Whether a breach has occurred is dependent upon the objective standard of a “reasonably prudent person” in relation to the attendant circumstances. For instance, a driver traveling at 55 mph on a highway in clear weather conditions that strikes another vehicle may or may not have been negligent depending on the other factors present. However, if the car was traveling at 55 mph during a major snowstorm, such behavior would almost undoubtedly constitute a breach of the duty of care owed. Causation – Finally, the injured drive must be able to prove that the other party was the actual and legal cause of the accident and resulting severe injuries or wrongful death. The reason for the requirement to prove causation comes down to fundamental fairness. For example, a driver that is texting while driving northbound on a roadway is almost undoubtedly engaging in negligent behavior and depending on the jurisdiction may be negligent per se. If an accident occurs on the southbound side of the road due to a tailgating driver who has insufficient stopping distance for an upcoming traffic light, it would be fundamentally unfair to hold the texting driver liable for an accident he or she played no part in causing despite his or her negligence.\nIn other cases, such as in a road rage incident where an intended physical altercation occurs, the injury victim may bring a lawsuit for an intentional tort. Intentional torts include assault, battery, and the intentional infliction of emotional distress (IIED).\nHave You Suffered a Serious Injury Due to a Road Rage or Aggressive Driving Incident?\nInjuries due to aggressive driving practices like speeding, unsignaled lane changes, running stop signs and stop lights can be severe or life-threatening. Likewise, injuries that may arise due to a road rage incident are often grave due to the inflamed passions and impulsive nature of such incidents.\nIf you or a loved one has been involved in a serious accident or event that produced catastrophic, life-altering injuries an experienced Delaware County car accident lawyer of The Reiff Law Firm may be able to fight for you. We are dedicated to seeking a favorable resolution for all of our clients. To that end we will handle all negotiations with the insurance company and, if required, litigate the matter to fight for the compensation a severely injured or wrongfully killed individual needs and deserves. To schedule a no-cost, private personal injury consultation call (215) 709-6940 today.", "pred_label": "__label__POS", "pred_score_pos": 0.8235788345336914}
{"content": "EMOTIONAL INTELLIGENCE WORKSHOP “Emotional intelligence is not the opposite of intelligence, it is not the triumph of heart over head – it is the unique intersection of both” “It’s amazing how once the mind is free of emotional pollution, logic and clarity emerge.”\nIn this 2-day immersive and insightful workshop, we unpack the components that are emotional intelligence. The workshop is designed to allow delegates to understand and manage their own emotions and the emotions of others. Combined with theoretical principles and experiential exercises that create insight, a deep dive into self and a depth of understanding self, delegates walk away armed with practical solutions and actions based on this understanding.\nEQ is playing a major role in business and leadership today: a skill that highlights the importance of interpersonal and intrapersonal relationships in personal and professional life. What will you learn? Understand my EQ profile and how this shows itself in the workplace; The 4 quadrants of being emotionally intelligent; Investigate and understand individual EQ skills and how this impacts my role; How do you recognise and understand your emotions; Manage Your Emotions and explore your triggers; Control or redirect disruptive impulses and moods; Utilising the EQ dictionary; Interpret your PDA assessment into your EQ action plan. What will you need? Your PDA profile – what is PDA?; An open mind; The courage to be vulnerable; A dose of self-honesty.", "pred_label": "__label__POS", "pred_score_pos": 0.6663901805877686}
{"content": "The Knox Community College [KCC] which began in 1975 is a co-educational institution located in Spalding, Jamaica. It operates four campuses: Spalding, Cobbla, May Pen and Mandeville. Though the College began with only three academic programmes, today there are over fifty [50] programmes in a variety of disciplines which culminate in the award of certificates, diplomas, associate’s and bachelor’s degrees. KCC is a leading educational institution which operates under the auspices of the United Church in Jamaica and the Cayman Islands and the Ministry of Education, Youth and Information. It serves the educational needs of all students in central Jamaica.\nThe College has several layers of governance which include the Trustee Board; the Board of Management; the Principal; two Vice Principals and a Bursar. KCC has some 1300 students are enrolled .\nThe College in responding to emerging needs and national strategic priorities seeks to maintain relevance within the regional and local landscape thereby positioning itself to be a premier institution. This strategic compass then brings into sharp focus the activities it must undertake to accord with Vision 2030. This strategic compass period revolves around five strategic goals, namely:\nIn January 2019, the Principal launched the strategic planning process with a special meeting with faculty and staff. The discussion which was aimed at providing a critical interrogation of the institution was led by a facilitator who had international, regional and local experience. In preparing for the assignment, the facilitator examined trends in tertiary/post-secondary education and a SWOT analysis which had been undertaken three months prior. Subsequent to that, a one-day session in March 2019, yielded the outputs of focus group discussions on issues related to accountability, performance, the involvement of the private sector, funding, curriculum, instruction, inclusion, MIS, faculty, staff, students, and infrastructure.\nIn August 2019, a two- day management retreat saw stakeholders of the College agreeing on what philosophies should drive the operations of the institution. They also identified and deliberated on the initiatives KCC should undertake over the next five years that would result in transformation.", "pred_label": "__label__POS", "pred_score_pos": 0.881309986114502}
{"content": "Retirement Planning\nWithdrawal Scheduling for Qualified Plans Taxation Cash Flow Investment and Social Security Integration\nThe key to a comfortable retirement is not just how much you save but how well you manage your assets. With a comprehensive retirement plan, you can avoid high fees, unnecessary taxation, insufficient savings rates and unreal expectations that commonly threaten investments and savings.", "pred_label": "__label__POS", "pred_score_pos": 0.977662980556488}
{"content": "What is a face? And what might it mean to be without one? This talk considers these, and related, questions through a reading of Ralph Ellison’s seminal novel Invisible Man. Specifically, I consider the deployment of the concept-metaphor of “facelessness” in Ellison’s text as a means of theorizing the matter of Black affect. I argue that Ellison’s rendering of Blackness as facelessness makes a key intervention into theories of affect which center on the face as the primary site of the affective encounter. Breaking with dominant conceptions of the face as a universal, anatomical reality or an ethico-affective horizon, Ellison demonstrates that the face is the product of obliterative violence––a social, political, and historical construction contingent on Black abjection.", "pred_label": "__label__POS", "pred_score_pos": 0.9128065705299377}
{"content": "If you don’t know where you want to be, it’s impossible to create a roadmap to get there. Without a vision rooted in your mission, the mission risks stagnation. We believe every organization needs a strategic plan. Stakeholders must know why your organization exists, clearly understand the primary beneficiaries, agree on the opportunities and challenges, and articulate how your organization contributes to the greater community.\nConstructing a plan is a dynamic, interactive process that promotes buy-in. The “roadmap” will result from the involvement of stakeholders in a process that involves interviews, focus groups, surveys and assessments guided by our consultants.\nWhat emerges is a plan that steers all of your activities so participants not only have buy-in but are held accountable for outcomes outlined in the plan. A feasibility study can provide additional helpful insights for your nonprofit. We specialize in a variety of nonprofit sectors, including the arts, culture, community, human services, educational, religious and Catholic fundraising.", "pred_label": "__label__POS", "pred_score_pos": 0.9830154180526733}
{"content": "A common way to model decision maker (DM) preferences in multiple criteria decision making problems is through the use of utility functions. The elicitation of the parameters of these functions is a major task that directly affects the validity and practical value of the decision making process. This paper proposes a novel Bayesian method that estimates the weights of criteria in linear additive utility functions by asking the DM to rank or select the best alternative in groups of decision alternatives. Our method computes the entire probability distribution of weights and utility predictions based on the DM's answers. Therefore, it enables the DM to estimate the expected value of weights and predictions, and the uncertainty regarding these values. Additionally, the proposed method can estimate the weights by asking the DM to evaluate few groups of decision alternatives since it can incorporate various types of inputs from the DM in the form of rankings, constraints and prior distributions. Our method successfully estimates criteria weights in two case studies about financial investment and university ranking decisions. Increasing the variety of inputs, such as using both ranking of decision alternatives and constraints on the importance of criteria, enables our method to compute more accurate estimations with fewer inputs from the DM.", "pred_label": "__label__POS", "pred_score_pos": 0.917790949344635}
{"content": "Digital identity apps will witness a significant growth\nJuniper Research has found that the number of digital identity apps in use will exceed 6.2 billion in 2025, from over 1 billion in 2020.\nBesides, civic identity apps will account for almost 90% of digital identity apps installed globally in 2025.\nThey will overtake the number of digital identity cards in use in 2023, with the number of apps in use 41% higher than cards by 2025.\nThis rise will be driven by the increasing use of civic identity in emerging markets and the lasting impact of the pandemic.\nThe report identified that the shift to digital services during the pandemic globally will stimulate fast growth in civic identity; growing by 467% between 2020 and 2025, as robust onboarding and verification for digital services become vital.\nWe’ve reported that Accertify has announced the launch of Digital Identity solution to help organizations deal with the growth in fraudulent online account openings and account takeovers.\nSEE ALSO:", "pred_label": "__label__POS", "pred_score_pos": 0.87752765417099}
{"content": "We present five experiments that examined Wegner’s (1994) theory of ironic processes of mental control in reactive motor performance under pressure for the first time. In Experiments 1, 2 and 4, we conducted specific examinations of the incidence of ironic error using a reactive motor task. In Experiments 3 and 5 we provided the first tests of whether task instruction moderates the incidence of ironic errors. The task required participants to react to a series of three primary color balls as they rolled down a chute under low- and high-anxiety conditions. Measures of anxiety, heart rate, heart rate variability and muscle activity confirmed the effectiveness of the anxiety manipulation. Experiments 1, 2 and 4 revealed that anxiety increased the number of ironic errors. In Experiments 3 and 5, we provided the first evidence that instructional interventions can reduce the incidence of anxiety-induced ironic performance errors in reactive motor tasks.", "pred_label": "__label__POS", "pred_score_pos": 0.6298503875732422}
{"content": "One measure of success is centering the voices of the individuals and groups we work with. A recent review of media coverage of the 61 individual trainees in our 2019 spokesperson training cohort identified a 56-percent increase in coverage of them following their attendance at our two-day in-person training, continuing a previous positive pace. That additive value from us results in our partners' views on key issues reaching and persuading more people.", "pred_label": "__label__POS", "pred_score_pos": 0.952081561088562}
{"content": "The Therapy Services team continues to do assessments and provide advice for people with disabilities to support them in reducing the challenges and barriers they face in everyday life.\nOccupational Therapy is an integral part of our holistic approach, which aims to support the specific needs and goals of the person concerned. Occupational Therapy services are provided to children aged 0-6 years through the Early Childhood Early Intervention (ECEI) pathway; to children and adolescents aged 7–18 years, and to adults who have an NDIS plan.\nChildren and adults with a disability are supported to engage actively and participate in their own lives to meet their goals. Occupational Therapy supports social and emotional development and wellbeing, and assists to address trauma through sensory processing and regulation Functional Capacity assessments to assist the person in accessing the NDIS supports they require to help them to meet their goals Psychosocial support – assistance with managing mental health issues, emotional regulation and self-care Equipment and aids – Our therapists assess and prescribe the most appropriate equipment and assistive technology (e.g. specialised wheelchairs), and home modifications to enable independence through access, mobility and participation in activities of daily living such as showering, dressing, meal preparation, and social activities Home visits are provided for people in the community and a sensory gym is available where therapy for children can be delivered in a safe and fun environment\nSupport Coordination Support Coordinators assist people to understand their NDIS plan, connect and co-ordinate their supports, and develop capacity and resilience to manage their plan into the future. A Support Coordinator can assist with the implementation of supports in the plan, coordinate assessments, reports and service proposals, support the participant through identifying and selecting providers, monitoring plan and outcomes and plan expenditure.", "pred_label": "__label__POS", "pred_score_pos": 0.8802170157432556}
{"content": "Abstract\nIn this study, we conducted a questionnaire survey to understand requirements related to encouraging participation in mutual interchanges for the elderly, known as \"salon activities\". Our subjects are middle-Aged and elderly residents of apartment complexes. Findings were obtained using a causal model via SEM. In determining salon activities, such as in meetings, it's effective to appeal to the necessity of \"preparation for disasters and old age.\" During the activities, it's effective to examine policies that foster participation in \"salon activities that give purpose and a sense of culture\" related to daily life. It's important to suggest participation before aging progresses.\nKeywords Apartment Complexes Causal model Elderly People Mutual Support Neighboring communication Structural Equation Modeling ASJC Scopus subject areas Environmental Engineering", "pred_label": "__label__POS", "pred_score_pos": 0.6116753816604614}
{"content": "A Town Hall event addressing the impact of underage drinking was held in December at the Ohio Valley Mall. Guest speakers included The Honorable Mark Costine--Belmont County Juvenile Judge, Belmont County Sheriff Dave Lucas, and Julie Bray of Pennsylvania. Each speaker addressed their connection to the underage drinking issue, as well as other destructive behaviors that young people engage in.\nJudge Costine and Sheriff Lucas both addressed underage drinking from the legal side, citing the number of cases they deal with as well as the specific damage they witnessed. Sheriff Lucas noted a case he worked on previously where numerous teens were severely injured and one deceased from a lethal batch of moonshine. The provider of the alcohol in that case, a 19 year old, was charged with involuntary manslaughter.\nJulie Bray brought an a different perspective to the event, detailing the negative impact underage drinking had on her life as a teenager. Specifically, Julie discussed a 1990 car accident in which four of her best friends were killed as a result of her and another friend drinking and driving. Julie emphasized the horrendous impact that the car accident had on her life and the extent to which it really \"wasn't worth it\" for a night of partying. She addressed the youths in the crowd saying, \"I've been in your shoes...when I was your age, I didn't want to listen to adults either, but if I had I wouldn't be a murderer.\"\nStudents from a local school were also there to provide statistics related to drinking and driving for the crowd. Among those cited at the event were the following:\nEveryday 28 people in the United States die in alcohol-related motor vehicle accidents.\nThe annual cost of alcohol-related crashes totals more than $44 billion.\nThe average drunk driver drives intoxicated 80 times before being stopped for their first OVI offense.\nIn addition to the speakers, ODOT's Belmont County garage brought over a distracted driving simulator for attendees to experience the negative effects of distractions such as being intoxicated or texting on driving.", "pred_label": "__label__POS", "pred_score_pos": 0.7146897315979004}
{"content": "Circuit court upholds OSHA citations in PSM case Posted October 29, 2020\nIn a recent ruling, the 10th circuit upheld OSHA citations in a process safety management (PSM) case, stating that boilers can be a part of a covered process, even though they do not contain hazardous chemicals. The court determined that boilers can be interconnected to a covered process – so if the boiler explodes, a PSM violation can occur. In this instance, the boiler was connected to two other parts of a refinery that did contain highly hazardous chemicals.\nBackground\nAfter a boiler exploded at a refinery, OSHA cited its owner for violating §1910.119, which creates a standard for process safety management (PSM) of highly hazardous chemicals. The Occupational Safety and Health Review Commission (OSHRC) upheld the violations. The refinery argued that §1910.119 does not apply to the boiler that exploded as it does not contain highly hazardous chemicals.\nIn its ruling, the court noted that the regulation defines “process” as “any activity involving a highly hazardous chemical,” and that the phrase “any activity involving” is broad enough to mean vessels need only be part of any activity that involves a highly hazardous chemical. In this case, the boiler was interconnected by a pipeline to two parts of the refinery that did contain highly hazardous chemicals.\nThe 10th circuit covers Oklahoma, Kansas, New Mexico, Colorado, Wyoming, and Utah, as well as those portions of the Yellowstone National Park extending into Montana and Idaho.\nThis article was written by Rachel Krubsack of J. J. Keller & Associates, Inc.", "pred_label": "__label__POS", "pred_score_pos": 0.8458953499794006}
{"content": "Basic conditions\nTo assess how much you can borrow, lenders are now required to scrutinise borrowers' incomes, outgoings and credit history closely and apply strict affordability criteria, ensuring that borrowers can comfortably afford their repayments now, and in the foreseeable future. All mortgage lenders are bound by the same general principles and criteria to assess borrower affordability, but there are slight variations in the way they apply them. We can help you present your application in a positive light, to the right lender, saving you time and stress. Here are some of the factors lenders take into account when making their decision:", "pred_label": "__label__POS", "pred_score_pos": 0.8454100489616394}
{"content": "Eat in a Healthy Calorie Deficit\nUltimately, losing weight is all about calories in, calories out. In order to lose weight, you have to burn more calories than you take in. \"You have to create a deficit of 3,500 calories to lose one pound,\" explained registered dietitian and ACSM-certified personal trainer Jim White, owner of Jim White Fitness and Nutrition Studios. \"This can be done by burning extra calories through exercise or reducing your intake of calories, but the best way is to use a combination of both methods. This ensures that you're giving your body enough nutrients during periods of weight loss.\"\nHowever, eating in a 3,500-calorie deficit doesn't guarantee an exact weight loss of one pound. There are a lot of other factors that impact how your body loses weight, including stress, sleep, and hormones.\nAlthough you should eat in a calorie deficit, he doesn't recommend anyone eat fewer than 1,200 calories a day. And since calorie needs are highly individual from person to person, Jim recommends meeting with a registered dietitian if you can to assess your needs and your goals. If that's not a possibility, you can use this formula to calculate your estimated calorie deficit for weight loss.", "pred_label": "__label__POS", "pred_score_pos": 0.5998625755310059}
{"content": "On February 7, 2014, Public Record Media received a letter from the Justice Department’s Office of Information Policy (OIP) regarding one of its pending administrative appeals. In its letter, OIP stated that a 2013 decision by the Office of Legal Counsel to withhold legal memos about the National Defense Authorization Act (NDAA) of 2012 was correct.\nOur NDAA request touched upon two separate policy areas that PRM has followed closely – the scope of presidential powers under the NDAA, as well as the ability of federal agencies to withhold final legal opinions from public disclosure.\nPRM pursuit of NDAA records\nFor over two years, PRM has sought information about detention powers granted under the 2012 NDAA. The NDAA is an annual, omnibus military spending bill that often contains other defense-related provisions, and its 2012 iteration included provisions relating to the indefinite military detention of individuals. Provisions 1021 and 1022 of the Act made explicit the President’s authority under the post-9/11 Authorization for the Use of Military Force (AUMF) to detain any person who was part of, “or substantially supported, al-Qaeda, the Taliba, or associated forces” under the law of war, “without trial, until the end of hostilities authorized by the AUMF.”\nMilitary detention controversy\nThe detention-related provisions of the 2012 NDAA became the subject of public controversy after their passage, due to concerns that the provisions could be used to detain American citizens in a broad range of circumstance, including inside the United States itself. The indefinite duration of the detentions authorized by the NDAA also raised concerns about due process and related constitutional issues.\nThe military detention of civilians had been effectively prohibited since the passage of the Posse Commitatus Act in the aftermath of the Civil War. However, the Bush administration confined a small number of U.S. persons in domestic military brigs in the years after the 9/11 attack, raising renewed controversies about the use of indefinite, military detention.\nThe Bush-era military detentions split circuit and appellate courts. The administration eventually charged one of its U.S. detainees – Jose Padilla – with a series of criminal charges, ending his period of military detention without charge. The Obama administration took the same route with the last domestic military detainee – Ali Saleh Al-Marri. Since the Supreme Court did not end up acting on the al-Marri or Padilla cases, a patchwork of lower court case law remains, some of which could be used to justify future, indefinite military detention.\nThis legal ambiguity is what has fueled concerns over the content of the NDAA, even in the face of language in the law itself that appears to limit its reach. Section 1201(e) of the NDAA notes that,\n“Nothing in this section shall be construed to affect existing law or authorities relating to the detention of United States citizen, lawful resident aliens of the United States, or any other persons who are captured or arrested in the United States.”\nHowever, the case law landscape left over from the post-9/11 years (which could certainly be viewed as “existing authority”) may yet authorize detentions of U.S. citizens in the United States. Likewise, the Obama administration has articulated guidance on the NDAA that seeks to limit its domestic reach, but such guidance is at the discretion of the White House, and could be changed to give the NDAA broader effect.\nPRM’s January 2012 FOIA request\nIn January of 2012, PRM submitted a Freedom of Information Act (FOIA) request to the Office of Legal Counsel (OLC) seeking documents pertinent to the President’s military detention powers under a variety of legal authorities, including the 2012 NDAA. For background, the OLC is frequently relied upon by executive branch agencies to evaluate legal issues and provide definitive guidance on a variety of matters.\nThe OLC responded in February of 2012, and noted that it held fourteen responsive documents. OLC also set out its decision to withhold each document in its entirety, asserting that the records were protected from disclosure by the deliberative process privilege under FOIA’s Exemption Five. This exemption can be used to withhold attorney-client communications and other “deliberative” discussions from disclosure under the FOIA. OLC also noted that it was invoking Exemption Five to protect presidential communications.\nKnowing that OLC held responsive documents, PRM reformulated its request and attempted to obtain the records a second time.\nFinal opinions under FOIA\nPRM believes that legal opinions – particularly final opinions – are valuable government records, because they provide the legal basis for government actions. By understanding the scope of a legal opinion, members of the public can anticipate government actions within a defined set of circumstances. Such an understanding is one of the underpinnings of a free society, and a key to government accountability.\nThe importance of public access to final legal opinions is reflected in the text of the Freedom of Information Act itself, which states that,\n“Each agency shall make available for public inspection and copying … final opinions, including concurring and dissenting opinions.”\nRecognizing this, FOIA case law makes it clear that the deliberative process privilege and other FOIA exemptions cannot be used to withhold materials that are “post-decisional” in nature. In other words, once a decision has been made by a government agency, records that set forth that decision should be publicly available. For instance, the U.S. Supreme Court’s Coastal States Gas Corporation case holds that an “agency shall not be permitted to develop a body of ‘secret law’ used by it in its discharge of its regulatory duties and in its dealings with the public, but hidden behind a veil of privilege.”\nPRM’s April, 2012 FOIA request\nIn April of 2012, PRM sent a reformulated request to OLC seeking a more limited sub-set of records pertinent to the 2012 NDAA. PRM’s request also explicitly stated that it was only seeking records that constituted “final determinations of policy or final opinions” that were “post-decisional in nature.”\nOLC eventually responded to that request by confirming that it held four responsive documents, but that it was withholding all of them under FOIA Exemption Five. PRM appealed the withholding via administrative appeal to the Office of Information Policy.\nOLC letter of June, 2013\nOn June 25, 2013, OLC sent a letter to PRM in response to its administrative appeal. In its letter, OLC characterized its NDAA opinions as “final opinions” of the agency, but also noted that they were not “post-decisional” materials. Instead, OLC categorized the opinions as pre-decisional legal advice to its client agencies. Because of this clarification, OLC claimed that its four documents were not – in fact – responsive to PRM’s FOIA request.\nOIP Administrative determination\nUpon administrative review, OIP affirmed OLC’s withholding of the NDAA memos. OIP’s Sean O’Neill wrote that,\n“OLC informed you that it does not maintain records such as those you described because all of OLC’s legal opinions and memorandum are pre-decisional. In light of your clarification of the scope of your request and OLC’s subsequent response, I have determined that OLC’s response was correct.”\nOIP’s recent determination affirms a much longer-term practice by OLC attorneys. For years, the OLC has maintained that its opinions are merely legal advice to clients, and has chosen to minimize their authoritative effect on federal agencies. OLC opinions have been used as the principle legal authority undergirding many of the government’s most controversial actions, including the Bush administration’s torture and warrantless wiretapping programs.\nPRM believes that any final legal memoranda that government actors rely upon to guide their actions should be available for public review. Our opinion is shared by organizations such as Citizens for Responsibility and Ethics in Washington (CREW), which filed a lawsuit against OLC last year. CREW’s lawsuit seeks to make all of OLC’s final opinions public, by seeking to enforce the FOIA’s explicit language about final legal opinions. More information about CREW’s lawsuit is available here.\nIn the coming weeks, PRM will continue its pursuit of NDAA-related legal opinions to seek clarity on how these provisions of law are interpreted by federal agencies.", "pred_label": "__label__POS", "pred_score_pos": 0.518545389175415}
{"content": "Abstract\nObjectives : This study has been carried out with the aim of investigating motor, cognitive and executive functions of a group of accident-prone drivers. Seventy professional accident-prone drivers with major faults and 30 drivers recognized as good and safe drivers, were examined using tests that assessed reaction time, recognition, memory, attention and concentration, as well as tests assessing decision making and response selection. Method: Results : From among the applied tests, perseveration error scores in Wisconsin Card Sorting Test (p<0.01) and reaction time for visual search (p<0.01) significantly differentiate between the accident prone and safe bus drivers. Scores on the visual search test showed highest correlation with IQ among the measures utilized (r=0.35, p<0.01). However, the scores for visual search test did not show significant correlation with other tests except for response errors in continuous performance test (r=0.24, p<0.001), and perseveration errors in Wisconsin Card Sorting Test (r=0.22 p<0.05). Age showed a positive and significant correlation with IQ scores (r=0.39, p=<0.001), response errors in continuous performance test (r=0.38, p=0.001) and reaction time for visual search test (r=0.23, p=0.05). Neuropsychological tests can diffe-rentiate accident-prone from safe drivers. However, regarding the limitation in the validation of this tool, one should be careful in generalizing the results. Conclusion:\nType of Study: Original Research\n| Subject: Psychiatry and Psychology\nReceived: 2009/03/25 | Published: 2009/02/15\nSend email to the article author", "pred_label": "__label__POS", "pred_score_pos": 0.5572521686553955}
{"content": "My first experience with hospital chaplaincy came when my father was dying of cancer, in my mid-30s. Through this difficult time, the chaplains brought our room such peace and calm. It was a profound gift and blessing. One chaplain in particular stands out in my mind. He came to us in the moments after my father passed, and offered us a blessing. He was able to comfort us in a way that was both reassuring and peaceful, holding the space that beautifully allowed us to process, cry, and also laugh. In the years following my father’s passing, I continued to think of the chaplains that spent time with us. The experience simmered in my mind and heart for a long time, until I finally began to wonder if I could do this job, as well. This question led to a discernment process, helping me find chaplaincy as a vocation and calling.\nNow, I am a newly minted hospital chaplain, having trained for this role for several years — going through theology school and onsite clinical pastoral training, and balancing group reflections and learning with practical experience with patients. I deeply love discovering new connections with people and supporting others in their spiritual journeys, and look forward to doing this as a profession. Through this training, I have learned so much about myself, and realize I have much still to learn, especially in recognizing opportunities for growth in my understanding of myself and in my faith.\nI will never forget the first room I stood in front of during my training at the hospital. I knew I was supposed to be there. I was confident of my discernment and calling. Still, I was terrified to walk in. What if I did the wrong thing? How would I know what to say? What if I couldn’t connect with the patient? I was afraid of all the mistakes I could make and all the things I might forget to do. As I stood outside that door, I listened to my fears, and realized something even deeper — I was afraid of my own imperfections.\nI stood in the hallway for a few moments, leaning into this fear. I doubted everything. I began to wonder if I knew enough, and more so, if I was enough. Then I took a deep breath, and did the only thing I knew to do, to call on God for help. Listening to God brought me on this journey to chaplaincy in the first place. If he wanted me there, I needed to lean on him now, more than ever. I asked God to guide my words and my steps and to help me in this work. I asked God for a sense of calm and confidence. And I also asked God for help and for self-acceptance of my imperfections.\nAfter a few more deep breaths, I knocked on the door and began the visit with the patient. He was sitting quietly in his dark room, his head in his hands. I did not know why he was in the hospital. Was he battling cancer? Recovering from surgery? Struggling with depression? I had no idea. I walked in anyway, and said “Hello.” It wasn’t a perfect visit. I probably even said something wrong. However, one thing I do know is that I showed the patient,\nI was there. I was present in the room asking him how he was doing and if I could support him. I was there to listen to his concerns and fear and show that I care. Even if I misspoke or struggled to find the right thing to say, at least I could offer connection and caring. It didn’t matter if I was perfect, it mattered that I was there. As I walked out of the room, I immediately realized that God had been there with me, guiding me and helping me have strength to face my fears. God, alone, gave me the push to walk into the room, despite my doubts, and he gave me the comfort I needed to accept my imperfect self and offer my presence to another person.\nWe all have moments of fear and doubt. I see now how God is always present and guiding me through these difficult times, allowing me to confront and acknowledge these insecurities. I find I must remember to call on God for strength and calm during these times of self-doubt. God’s love surrounds all of us in unconditional loving care. When I open up to this deep love, I find acceptance of my imperfections, and with this, such beautiful new space for growth and faith.", "pred_label": "__label__POS", "pred_score_pos": 0.7294642925262451}
{"content": "Today at 10:15 AM ET, WTI (West Texas Intermediate) crude oil prices fell 0.8%. Profit booking could be one of the factors behind oil’s decline. Today, the API (American Petroleum Institute) planned to report the inventory report for the last week. A Reuters poll expects a fall of 3.9 MMbbls (million barrels) and a rise of 3.2 MMbbls, respectively, in the API’s crude oil and gasoline inventories level.\nHowever, if the actual data disappoints the market’s expectations, we could see a further downside in oil. For the week ended December 27, the API’s reported draw in crude oil and gasoline inventories were higher than the market’s expectations.\nCrude oil inventories declined by 7.8 MMbbls compared to the Reuters poll forecast for a decline of 3.4 MMbbls. Similarly, gasoline inventories declined 0.8 MMbbls, while the Reuters poll forecast an increase of approximately 2 MMbbls.\nCould Trump push oil to $100?\nThe Trump administration is keen to stop any sudden rise in oil prices. In September, Houthis claimed responsibility for drone attacks that wiped out a significant portion of Saudi Arabia’s oil output temporarily. As a result, oil prices spiked 14.7%. However, within a week, WTI crude oil prices pared their gains.\nAt that time, President Trump tweeted, “locked and loaded” in reference to Iran. However, instead of using military force, the Trump administration came out with stringent sanctions to hurt Iranian interests.\nHowever, after Qassem Soleimani’s killing, we’re seeing a different scenario. According to a CNBC report, Iran’s supreme leader Ayatollah Ali Khamenei pronounced “harsh revenge” Soleimani’s killers. Khamenei stated, “Even if there is consensus on the weakest scenario, carrying it out can be a historic nightmare for the Americans.” Last week, the Pentagon stated that the drone strike was carried out on Trump’s instructions.\nAnalysts believe that Iran could hit US interests in the Middle East, including new attacks on oil infrastructure in the region. Also, Iran ignored the nuclear agreement limitation and proceeded with its ambition to design a nuclear bomb. This could motivate the US to stop Iran from transforming into a nuclear power.\nSince October 2013, WTI crude oil prices have not closed above $100 per barrel. Oil’s oversupply situation could persist in the first two quarters of 2020. However, if the Iran’s Supreme National Security Council’s “13 revenge scenarios” could choke the Middle East’s oil supplies, oil prices could test the $100 level. The United States Oil Fund LP (USO) provides exposure to WTI crude oil futures.\nEIA data\nTomorrow, the EIA (US Energy Information Administration) plans to release oil inventory data for the last week. The Reuters poll forecast a fall of 4.1 MMbbls in EIA’s crude oil inventories level. Gasoline inventories could rise by 2.7 MMbbls, based on the Reuters poll.\nFor the week ended December 27, the US crude oil inventories were on par with their five-year average. The inventories spread represents the difference between inventories and their five-year average. If the EIA reports a decline in crude oil inventories, then the inventories spread could move into negative territory, a bullish driver for oil prices.\nIn 2018, when active WTI crude oil futures were above the $70 level, the “inventories spread” was in negative territory. Yesterday, active WTI crude oil futures settled at $63.27 per barrel. Read What the Oil Inventories Spread Suggests for Oil Prices to understand this relationship.\nOil’s price target\nYesterday, oil’s implied volatility was 28.4%. After Qassem Soleimani’s killing, both oil prices and implied volatility rose. Usually, a rise in prices and a fall in implied volatility points to a sustainable rise in oil prices. Until Monday, US crude oil active futures were expected to close between $60.97–$65.57 per barrel. The API and EIA’s inventory data are crucial for oil’s upside.\nTo learn more about this price model, read Oil Prices: Implied Volatility Suggests Upside Is Intact.", "pred_label": "__label__POS", "pred_score_pos": 0.8764984607696533}
{"content": "Condominium and Cooperative Law in Arizona\nCondominiums and cooperatives are forms of \"common interest\" communities.\nThey are communities where each individual or family resident rents or owns an unit which is part of a larger building, containing other, similar, residential units. The residents are accountable responsible for the maintenance of the common areas of their living areas, such as gardens, walkways, lawns, and swimming pools. They typically meet this responsibility by paying a monthly fee to support this maintenance.\nIf you just look at one of these communities, you won't be able to tell whether it's a cooperative or a condominium community.\nThis is because there are no defining physical characteristics which are distinct to one type of cooperative community, but not the other. The significant differences aren't embodied in physical characteristics, but in the legal ownership arrangement governing the communities: in a condominium community, the residents own the units they live in. In a cooperative community, the units are rented.\nLaws and Regulations Concerning Common Interest Communities in Mesa, Arizona\nMesa, Arizona likely has numerous laws and regulations concerning common interest communities. Nonetheless, these are mostly limited to the laws and regulations (zoning, land use, etc.) that concern all real estate owners.\nYour day-to-day life in a common interest community will likelyy be impacted more by the rules set by the owner or manager of the property, rather than any local or state laws.\nBecause the land they occupy is typically private property, it is the owners of this property who make most of the rules that will affect your daily conduct. A responsible manager will typically make rules designed to balance your right to live as you please in your own residence, with the right your neighbors have to a clean, safe, and quiet living environment.\nSome of these rules, however, may not be enforceable, if push came to shove. This would depend on the particular laws of Mesa, Arizona which regulate landlords and tenants.\nCan a Mesa, Arizona Attorney Help?\nIf you are involved in an argument with your neighbor, in conflict with a zoning regulation, or in a dispute with your landlord, a reliable Mesa, Arizona real estate attorney can help you prevail.", "pred_label": "__label__POS", "pred_score_pos": 0.6116293668746948}
{"content": "Abstract\nThis paper involves the dynamic (stability) analysis of distributed drill-string systems. A minimal set of parameters characterizing the linearized, axial-torsional dynamics of a distributed drill string coupled through the bit-rock interaction is derived. This is found to correspond to five parameters for a simple drill string and eight parameters for a two-sectioned drill-string (e.g., corresponding to the pipe and collar sections of a drilling system). These dynamic characterizations are used to plot the inverse gain margin of the system, parametrized in the non-dimensional parameters, effectively creating a stability map covering the full range of realistic physical parameters. This analysis reveals a complex spectrum of dynamics not evident in stability analysis with lumped models, thus indicating the importance of analysis using distributed models. Moreover, it reveals trends concerning stability properties depending on key system parameters useful in the context of system and control design aiming at the mitigation of vibrations.\nKeywords Delay equations Distributed systems Drill-string vibrations Infinite dimensional systems Stability Stick-slip", "pred_label": "__label__POS", "pred_score_pos": 0.9981245994567871}
{"content": "Despite the large number of existing guidelines and protocols, we have realized that, unfortunately, these will not be enough to maintain a safe environment since they are not supported by:\nThe unique blueprints we have created, ensure that the measures taken to minimize the risk of exposure to COVID-19, are implemented continuously, adequately, and effectively,\nregardless of the type of establishment.\nUpon completion of any of our assessments, you will be granted with a visual aid to easily communicate your pledge to the public. –\na Trust Mark!\nWhen you see any of our Trust Marks, feel confident and at ease that you are in a safe environment.\nGetting the “in this together” Mark\nis possible for every business – It all begins with choosing the most suitable blueprint for you!\nSupported by a strategic communication framework, “\nin this together” fosters a preventive culture based on best practices, allowing individuals to understand the impact of their daily actions to maintain a safe environment.\nReturn to the\n“new normal” without feeling nervous, fearful, anxious, or unsafe.\nSupport your company to take the steps towards a safe environment culture.\nAssure there are ongoing measures in place to minimize the risk of exposure to COVID-19 in your workplace, or your favorite establishment.\nClearly communicate the actions that stakeholders should take to maintain a safe environment.\nProtect individuals at higher risk for severe illness by providing specific controls for them.\nYou are backed by a prevention and control management system.", "pred_label": "__label__POS", "pred_score_pos": 0.5708297491073608}
{"content": "Car accidents are, by nature, unpredictable. However, there are certain places where car crashes occur on a more regular basis. Knowing these patterns can help reduce the risk of an incident. In this article, we cover a few common accident scenarios and what you can do to avoid becoming a statistic.\nDespite fewer drivers on Missouri roads due to the ongoing Coronavirus outbreak and springtime stay-at-home orders, Missouri state troopers say they have seen a three percent increase in traffic fatalities for the year. Data from the Missouri State Highway Patrol show there were 174 deaths as of April 5\nth, compared with 168 deaths in the same time frame in 2019.\nGoldblatt + Singer is proud to sponsor MADD’s annual Walk Like MADD & 5K Race in St. Louis. MADD was founded by a mother whose daughter was killed by a drunk driver. This amazing organization combats drunk driving by ensuring that our community fully appreciates the dangers of drunk driving and by deterring people from getting behind the wheel while drunk.\nFive people lost their lives today in St. Louis car accidents.\nIn downtown St. Louis, two people were killed when their vehicle struck an interstate overpass on Highway 44.\nTwo pedestrians walking on a sidewalk at the intersection of Kienlen and Evanston avenues in Wellston were fatally struck when a car veered onto the sidewalk to avoid a collision with another car.\nGoldblatt + Singer personal injury attorneys regularly take over cases started by other lawyers. In recent years, many attorneys who do not specialize in handling auto accident cases try to learn as they go. Unfortunately, the injured party often ends up suffering again.\nOn October 11, 2014, Megan Mangene was driving home from work when a vehicle driven by Julie Behnen, traveling the wrong way on Highway 44, struck Megan’s vehicle head-on. According to the police, Ms. Behnen had been drinking at Helen Fitzgerald’s Irish Bar and Grill before the accident and had a blood alcohol content nearly three times the legal limit.", "pred_label": "__label__POS", "pred_score_pos": 0.8225759267807007}
{"content": "Although design defects have been linked to certain types of internal defibrillator leads, resulting in manufacturer recalls, the devices are often left in place, due to risks associated with attempting to remove the wires. However, the findings of a new study suggests that about one out of every three patients may eventually experience serious adverse health effects.\nIn a research letter published last month in\nJAMA Internal Medicine, researchers from Iceland found that one-third of patients who had recalled St. Jude Riata defibrillator leads suffered failures, lead fractures and other problems.\nThe leads were officially recalled in late 2011, due design problems and insulation defects, but doctors were advised to leave them in place unless a patient experenced problems.\nIn Iceland, following the recall, a program was put in place to monitor those who still had the defibrillator leads inside of them. The researchers looked at 52 individuals who had the recalled leads implanted from November 2002 to October 2009, and compared them to 50 patients who had implantable cardioverter defibrillators (ICDs) from other manufacturers from February 2010 through November 2012, to serve as controls.\nAccording to the findings, 19 of those who had the recalled device suffered lead failure, one of whom died, for a 36.5% failure rate. By comparison, those with leads that had not been recalled only had an 8% failure rate, with only four patients experiencing lead failure. Follow-up on both groups occurred over eight years.\nResearchers determined that those who had recalled St. Jude Riata leads had a 25% higher risk of lead failure. Ultimately, there were 15 total deaths in the recalled lead group by the end of the follow-up period, for a rate of 26.9%. That compares to only 10 deaths, or 20% in the control group.\n“The lead failures among patients who had the recalled leads occurred over the course of the follow-up time, indicating that leads should be monitored for the full dwell time,” the researchers concluded. “While there is still no clear consensus about the root cause of the Riata lead failure, we conclude that development of more durable ICD leads with regards to biomaterials and engineering design is warranted.”\nSt. Jude ICD problems\nSt. Jude Riata leads are small wires used to connect implantable cardiac defibrillators (ICDs) to the heart. They are designed to monitor the heart rhythms and deliver electric shocks if needed to restore normal heart beats.\nAbout 227,000 of the lead wires were sold worldwide before the manufacturer acknowledged that the insulation surrounding the wire may be prone to decay and erode, leaving exposed wires inside patients. This has caused many users to experience unnecessary shocks, or for the defibrillator to fail.\nIn late 2010, St. Jude removed the leads from the market amid reports of insulation failure, and a warning letter was sent to doctors about the risk of problems in late 2011, which the FDA classified as a St. Jude Riata recall. However, it was estimated that nearly 80,000 of the leads remained active in patients in the United States, as the process of attempting to remove the lead is risky and doctors often recommend keeping the defective lead in place unless there is evidence that it has failed.\nIn August 2012, the FDA issued a safety communication in response to concerns among individuals who still have one of the recalled St. Jude Riata or Riata ST leads, recommending that individuals undergo x-ray or other imaging exams to monitor the condition of the leads.\nIn 2015, St. Jude agreed to pay $14.75 million to settle nearly 1,000 defibrillator lead injury lawsuits, resolving most of the litigation.", "pred_label": "__label__POS", "pred_score_pos": 0.7170151472091675}
{"content": "Despite significant initial responses to therapy, treatment resistance remains the hallmark of metastatic disease. Our group is a multi-disciplinary team focusing on studying treatment resistance in advanced urological cancers. Since starting up five years ago, we have been integrating solid tumour and circulating cell-free DNA genomics, transcriptomics and epigenomics with functional studies to track tumour clone dynamics in patients progressing through multiple lines of treatment. Using this approach, we aim to identify cancer vulnerabilities to be exploited therapeutically and design clinical trials of biomarker-directed strategies for rational treatment selection and sequencing.\nSome of our recent work used plasma DNA to track androgen receptor (AR) gene aberrations in advanced prostate cancer patients and identified a strong association between plasma AR aberrations and resistance to second-line hormonal treatments. Our group have also identified a plasma DNA methylation signature associated with the presence of circulating prostate cancer DNA. These findings and others have led to the initiation of the PARADIGM study (NCT04067713, Plasma Analysis for Response Assessment and to Direct the manaGement of Metastatic prostate cancer) evaluating if the detection of circulating prostate cancer DNA is associated with treatment response.\nWe have integrated our plasma DNA analysis into multiple clinical trials, including the national platform STAMPEDE trial for men starting androgen deprivation therapy. This complements our work leading the genomic analysis of solid tumour material from this trial as part of the STRATOSPHERE consortium, aiming to characterise hormone-naïve prostate cancer from men with metastatic prostate cancer.\nWe are also part of multiple ongoing international efforts working to implement plasma analysis into clinical practice. In the PCF-SELECT international consortium we are developing a clinically useful plasma DNA targeted NGS assay and in the CRUK Accelerator Award funded PRIME project we are working to integrate all that we have learnt during these past years into a plasma based multimodal test for prostate cancer.\nResearch overview Funders\nOur group receives support from Cancer Research UK (CRUK), Prostate Cancer UK (PCUK), The European Union (EU), The Medical Research Council (MRC), the Prostate Cancer Foundation (PCF) and the Prostate Cancer Research Charity (PCRC), and our work wouldn’t be possible without the support of our patients and their families.", "pred_label": "__label__POS", "pred_score_pos": 0.610038161277771}
{"content": "May 10, 2018\nAfter experiencing delivery complications with my first daughter, it was evident that we would need to schedule a C-section for our second daughter. Scheduling and knowing your child's birthday months in advance is an odd and slightly disappointing feeling. However, I was about to find out that this scenario could be a positive thing for not only our baby, but others as well.\nAt one of my prenatal doctor appointments, I was handed a pamphlet for Unyts regarding birth tissue donation. I had never heard of it before. The doctor explained that the tissue of the placenta had great healing qualities and was used after various types of surgeries to help heal wounds. The only question I had was, \"What happens to my placenta if I don't donate it?\"\nThey throw it in the garbage!\nRight then and there I decided that I would donate my birth tissue. I couldn't help but think I would be wasting something if I didn't. A few weeks later I received a phone call from Unyts and answered some questions regarding my lifestyle to ensure my birth tissue would be healthy enough for donation, and it was as easy as that. When it came time for the birth of our daughter, I didn't notice anything different in the delivery room. We even received a beautifully knit blanket as a thank you for our donation. It's been almost two years and we still use that blanket.\nAshley Bushen\nBirth tissue mom\nLearn more about Birth Tissue Donation", "pred_label": "__label__POS", "pred_score_pos": 0.6261036396026611}
{"content": "\"effective\" po angielsku z przykładami - Słownik kolokacji angielskich\nWater provided places, suburbs and the town itself with the most effective protection. Finally, the plan would not provide effective protection of cities on both coasts. Vaccines would provide the most effective protection at the lowest cost. \"We recommend that it takes two methods to really have effective protection,\" she says. The question is: can this system really guarantee effective protection? In this regard, we ask that the talks focus on the effective protection of traditional names. This system contributes to the effective protection of the Union's financial interests. We need to continue to seek ways to provide greater, effective protection for European citizens. I think that is an essential tool of effective protection. This is an area where we need to show imagination in establishing effective legal protection.\nKliknij na wybrany nagłówek, aby rozwinąć grupy kolokacji, kolokacje oraz przykładowe zdania.", "pred_label": "__label__POS", "pred_score_pos": 0.8469802737236023}
{"content": "Sometimes a tooth that has undergone endodontic treatment fails to heal or continues to cause discomfort. On rare occasion, a tooth that had initially responded well to root canal therapy can become painful or diseased months or years later, usually due to bacterial contamination inside, causing root-end inflammation. In such situations, the tooth often can be maintained with a second endodontic treatment, or retreatment. This requires \"undoing\" the initial procedure, which may include removal of a crown, buildup, post, root filling material; and recleansing and enlarging of the entire root canal system. Then the canal spaces are repacked, and a new buildup and crown may be necessary. Occasionally a root canal can be retreated through an existing crown, where that restoration can be repaired and preserved. Retreatment cases are frequently more technically demanding than first-time-in root canal therapy, and often carry a less favorable prognosis. There are instances in which extraction, rather than retreatment, may be the treatment of choice.", "pred_label": "__label__POS", "pred_score_pos": 0.8630799055099487}
{"content": "Abstract\nThe present study aimed at investigating whether the effects of intergroup contact on support for discriminatory behaviours against immigrants was mediated by perceived threat from immigrants and positive beliefs toward immigrants. Using data from the Italian national survey on \"Discrimination by Gender, Sexual Orientation and Ethnic Origin,\" which followed a multi-stage stratified cluster sampling procedure, a representative sample of 5509 Italian residents (53.4% women), aged 18 to 74 years, participated. Findings showed that contact with immigrants was negatively related to perceived threat, and positively related to positive beliefs toward immigrants. Mediational analysis conducted by structural equation modelling, indicated that support for discriminatory behaviours was positively associated with perceived threat, and negatively associated with positive beliefs toward immigrants. Both variables together mediated the relationship between contact with immigrants and support for discriminatory behaviours against immigrants; individually, indirect relationships were also significant. To promote interaction between natives and immigrants by reducing the perceived threat and strengthening positive beliefs toward immigrants might lessen support for discriminatory behaviours against immigrants. © 2019 International Union of Psychological Science.", "pred_label": "__label__POS", "pred_score_pos": 0.6669149994850159}
{"content": "Today is the anniversary of the tragic shooting at Chardon, Ohio, High School. It's sad that we have anniversaries for violent incidents that occur in workplaces. Let's remember schools are workplaces for many. From every unfortunate incident we can learn lessons and improve on the future.\nThe shooting incident at Chardon High School is in the past, let's learn from it, and focus on the future. We can always glance in the proverbial rear-view mirror while moving forward and focusing on what's in front of us in the windshield). Intervention can work.\nA passive approach to a violent intruder (traditional lock-down and shelter in place) is not likely to be as effective as a proactive approach like we saw from Coach Hall in Chardon. It's always great to hear about ordinary people who can accomplish extraordinary things when they are empowered to improvise. adapt and overcome.\nPlease reload\nFeatured Posts\nI'm busy working on my blog posts. Watch this space!", "pred_label": "__label__POS", "pred_score_pos": 0.6803815364837646}
{"content": "A Facebook group dubbed the Freedom to Breathe Agency, or FTBA, is promoting fake face mask exemption cards featuring an eagle image reminiscent of the Department of Justice seal. Images of the laminated cards began circling social media on Wednesday and have been deemed fraudulent by the DOJ\nThe white cards, intended to prevent business owners from denying service to those without face masks, feature a red banner stamped with the words, \"Face Mask Exempt Card,\" and includes the DOJ ADA Violation reporting number and the DOJ seal. The bottom corner of the card depicts the group's logo, an eagle above the FTBA's website.\nThe card reads: \"I am exempt from any ordinance requiring face mask usage in public. Wearing a face mask poses a mental and/or physical risk to me. Under the Americans with Disability Act (ADA), I am not required to disclose my condition to you.\"\nIt goes on to include a threat of sorts to business owners:\n\"If found in violation of the ADA you could face steep penalties. Organizations and businesses can be fined up to $75,000 for your first violation and $150,000 for any subsequent violations. Denying access to your business/organization will be also reported to FTBA for further actions.\"\nWhile it is true that businesses are not allowed to question the nature of a person's disability or request documentation proving the ailment, when it comes to face masks, things get tricky. A number of states including New York, New Jersey, Pennsylvania and others enforced rules requiring residents to wear face masks when visiting essential businesses or using public transportation due to the coronavirus pandemic back in April. In Washington state, Governor Jay Inslee issued a public health order on Tuesday requiring individuals to wear a face mask in indoor public spaces as well as outdoor public areas where social distance guidelines can't be regulated.\nAt the height of the pandemic, people in states like Michigan and Colorado protested against stay-at-home orders and argued that mandatory face coverings infringed their rights.\nOriginally established as the Anti-Mask Task Force on June 1, the renamed FTBA was \"designed to stop face mask orders from spreading nationwide and globally,\" according to the group's Facebook page.\n\"Breathing is a vital biological activity to physical and emotional well being. Oxygen is No.1 nutrient for every living organism including humans. Wearing a mask is an unhealthy obstruction of oxygen flow that can lead to hypoxemia and hypoxia, can permanently damage the brain, lungs, heart and about any organ. We must protect our birth right to breathe. This is NOT negotiable,\" the group's mission statement reads.\nNewsweek has contacted the FTBA for comment but has not yet received a response.\nThe DOJ is already aware of the fake face mask exemption cards and wrote on its website that \"these postings were not issued by the Department and are not endorsed by the Department.\"", "pred_label": "__label__POS", "pred_score_pos": 0.8787815570831299}
{"content": "Fintech is the driving force behind the transformations within the finance industry. In the last ten years alone, there have been incredible advancements across retail banking, wealth management, and payments. Now, consumers are shifting attention to fintech for even more enhanced financial services, and the trend is gaining greater traction with every passing day. The global pandemic caused by COVID-19 has further increased the significance of fintech in the financial world. Therefore, let’s look at some areas that are emerging as key opportunities for entrepreneurs and will continue to be so beyond 2020.", "pred_label": "__label__POS", "pred_score_pos": 0.830213189125061}
{"content": "Minimally invasive selective neck dissection: a prospective study of endoscopically assisted dissection via a small submandibular approach in cT(1-2_N(0) oral squamous cell carcinoma.Ann Surg Oncol. 2014 Nov; 21(12):3876-81.AS BACKGROUND\nSelective neck dissection (SND) in clinical N0 (cN0) cases of oral squamous cell carcinoma (SCC) has been performed by surgeons using a retroauricular or modified facelift approach with robotic or endoscopic assistance. However, these procedures provide cosmetic satisfaction at the cost of possible maximal invasiveness. In this prospective study, we introduced and evaluated the feasibility as well as surgical invasiveness and cosmetic outcome of endoscopically-assisted SND via a small submandibular approach.\nMETHODS\nForty-four patients with cT1-2N0 oral SCC (OSCC) were randomly divided into two groups of endoscopically-assisted SND and conventional SND. Perioperative and postoperative outcomes of patients were evaluated, including the length of the incision, operating time for neck dissection, estimated blood loss during the operation, amount and duration of drainage, total hospitalization period, total number of lymph nodes retrieved, satisfaction scores based on the cosmetic results, perioperative local complications, shoulder syndrome, and follow-up information.\nRESULTS\nThe mean operation time in the endoscopically-assisted group (126.04 ± 12.67 min) was longer than that in the conventional group (75.67 ± 16.67 min). However, the mean length of the incision was 4.33 ± 0.76 cm in the endoscopically-assisted SND group, and the amount and duration of drainage, total hospital stay, postoperative shoulder pain score, and cosmetic outcomes were superior in the endoscopically-assisted SND group. Additionally, the retrieved lymph nodes and complications were comparable.\nCONCLUSIONS\nEndoscopically-assisted SND via a small submandibular approach had a longer operation time than the conventional approach. However, endoscopically-assisted SND was feasible and reliable while providing minimal invasiveness and satisfactory appearance.\nMeSH Pub Type(s) Language PubMed ID Citation Annals of Surgical Oncology,vol. 21, no. 12, 2014, pp. 3876-81. Ann Surg Oncol. 2014;21(12):3876-81. Annals of Surgical Oncology, 21(12), 3876-81. https://doi.org/10.1245/s10434-014-3833-0 Ann Surg Oncol.2014;21(12):3876-81. PubMed PMID: 24912615.", "pred_label": "__label__POS", "pred_score_pos": 0.808398962020874}
{"content": "This paper shows that effective information and communication processes are prerequisites for successful development.\nThey are the lifeblood of good governance; an integral part of empowering and enabling a healthy, vibrant civil society; essential for the creation of efficient and effective economies; and a critical component of social adaptation.\nThe case for communication addresses the challenge of using communication more powerfully as an agent of change to establish faster, more sustainable development.", "pred_label": "__label__POS", "pred_score_pos": 0.9998774528503418}
{"content": "Citizens have a critical role to play in advancing transparency, accountability, and effectiveness in the delivery of essential services. Smart Cities leverage technology to effectively engage citizens, efficiently provide services, improve participatory democracy, and enhance administrative efficiencies. Co-City mobile platform is one such solution. The Co-City App empowers citizens to report safety, by-laws, and service incidents to their municipality, while they receive updates and alerts from the municipality. Citizens are able to directly interact with their local government in a convenient and cost-effective manner.\nAutomate Incident Management:\nCo-City provides an intuitive web-based dashboard that enable municipal officials to instantaneously receive rich mobile data and capture incidents reported from multiple channels for appropriate action to be taken following an integrated workflow process. The Co-Safety Dashboard automates incident management, tracks incident progress and creates a single version of the truth within a municipality.\nGain Insights through Data Analytics:\nCo-City Dashboard provides data analytics capabilities that enables dynamic visualisation of incidents data in various reports and heatmaps. Data Analytics build intelligence of incident hotspots that can aid strategic deployment of resources, evidence-based decision making, and planning by management of the municipality.\nIntegration and Customisation:\nCo-City mobile platform has API capabilities to enable integration with other systems in a municipal environment. The system is customisable to cater for any service delivery environment whether there is a need to digitise incident management, integrate mobile apps and pro-actively engagement of citizens. It is a solution for Smart Cities that want to leverage technology and innovation to delivery services.", "pred_label": "__label__POS", "pred_score_pos": 0.9497386813163757}
{"content": "Graphene nanosheets have been prepared from fine graphite powders by a novel electrochemical exfoliation method using non-volatile sulfate salts. This new method utilizes a stainless steel wire cage and platinum wire electrodes to exfoliate pre-pelleted graphite powders into graphene sheets. Synthesized graphene samples have been characterized by Field Emission Scanning Electron Microscopy (FE-SEM), Raman spectroscopy, and Fourier Transform Infrared (FT-IR) spectroscopy. The obtained supernatant shows a stable suspension in DMF. This suspension was then used in organic solar cells (OSCs) as an additive to poly(3,4-ethylene dioxythiophene) polystyrene sulfonate (PEDOT:PSS). Organic solar cells have been prepared using Indium Tin Oxide (ITO) as the transparent conducting oxide, PEDOT:PSS-Graphene as the hole transport layer (HTL), Poly(3-hexylthiophene-2,5-diyl:[6,6]-Phenyl-C60-butyric acid methyl ester (P3HT:PCBM) as the active layer and Aluminum as the cathode, in ITO/PEDOT:PSS-Graphene/P3HT:PCBM/Al configuration. The photovoltaic cell prepared with graphene as an additive inside PEDOT:PSS exhibited over 66% improvement compared to the reference cells employing pure PEDOT:PSS.", "pred_label": "__label__POS", "pred_score_pos": 0.8710004687309265}
{"content": "From drought and bushfires, through to COVID-19 and recession. Australia’s food and agribusiness (F&A) sector has navigated major disruptions over the past 24 months.\nDespite these challenges, a report released today reveals that the contribution of Australia’s F&A sector to Australian annual GDP could surpass $200 Billion by 2030, more than 3 times greater than its current value of $61 Billion.\nCommissioned by the Food and Agribusines Growth Centre,\nCapturing the Prize(link to report) takes into account the current impact on the sector of COVID-19 to quantify the 10 Future Trends and 19 Growth Opportunities that – if pursued – will unlock the sector’s untapped potential of over $200 Billion within the decade.\nThe Growth Centre’s Managing Director, Dr Mirjana Prica said “\nCapturing the Prize is rich with the insights required to unleash this significant growth potential. However, making it a reality is not a forgone conclusion – if food and agribusinesses are to reap these rewards, business-as-usual will not suffice”. Capturing the Prize highlights a growing sentiment amongst F&A leaders – food and agribusinesses need to operate differently: adopting a whole-of-value-chain approach that unlocks value on either side of the farm gate. This would facilitate the scaling up necessary to boost competitiveness and ensure supply chain resilience.\nIn addition to identifying the 19 Growth Opportunities that could see the value of the Australian F&A sector soar beyond $200 Billion,\nCapturing the Prize also reveals that pursuing these growth opportunities is estimated to create an additional 300,000 jobs by 2030.\n“\nCapturing the Prize has the potential to transform the livelihoods of the sector’s 176,000 businesses, the majority being small-to-medium-sized, family-run businesses. It also has the potential to finally align industry direction, government policy, and commercial investment behind a shared target. This will focus efforts to see the sector’s contribution to Australian annual GDP exceeding $200 Billion by 2030,” said the Food and Agribusiness Growth Centre Chair, Dr Michele Allan", "pred_label": "__label__POS", "pred_score_pos": 0.902504563331604}
{"content": "Thursday, October 17, 2019\nHere's an upcoming free webinar from the National Center on Law & Elder Rights on November 12 at 2 est:\nLegal Basics: Self-Neglect and Hoarding Disorders When: Tuesday, November 12, 2019 at 11:00 a.m. PT/2:00 p.m. ET.\nLawyers working with older adults are likely to encounter challenges related to self-neglect and hoarding. Intervening in self-neglect cases can be very complicated. Clients who have a hoarding disorder may be living in conditions that make it impossible for them to live in safety, resulting in self-neglecting behaviors. This Legal Basics session will discuss the most common root causes of self-neglect and hoarding disorders, provide insight into the complexity of the issues, and offer suggestions of how to offer help. The webcast will also explore legal issues and the lawyer’s role when working with older adult clients.\nThe webcast will cover:\nUnderstanding self-neglect and helping without harming. The line between self-neglect being a human services issue and a legal issue. Assessing possible hoarding disorder cases. Suggestions when working with a person with hoarding disorder. When hoarding becomes a legal issue.\nThis webcast is being presented as part of NCLER’s forthcoming Elder Justice Toolkit. Stay tuned for more!\nhttps://lawprofessors.typepad.com/elder_law/2019/10/webinar-on-self-neglect-and-hoarding.html", "pred_label": "__label__POS", "pred_score_pos": 0.7696160078048706}
{"content": "Centre for Ecology & Hydrology) Pioneering research led by the UK Centre for Ecology & Hydrology (UKCEH) has devised the first system that classifies lakes globally, placing each of them in one of nine 'thermal regions.' This will enable scientists to better predict future warming of the world's lakes due to climate change, and the potential threat to cold-water species such as salmon and trout.\n(", "pred_label": "__label__POS", "pred_score_pos": 0.9194259643554688}
{"content": "Craniometric parameters including cranial and orbital indices have been employed to determine the sex of a person in forensic medicine. These parameters are usually population specific. However, they have not been documented for a black Kenyan population. This study aimed at calculating the sex differences in the cranial and orbital indices. The cranial vault height, glabellomaximal length and orbital height and length were measured from 150 crania (80 male and 70 female) using a sliding vernier caliper. Cranial and orbital indices were calculated and the results were analyzed. The cranial index was 71.04 for the male and 72.37 for the female (P=0.095). The orbital index was 82.57 and 83.48 for the male and female, respectively (P=0.472). From these results, although the cranial and orbital indices are within range of previously reported values for an African population, they cannot be used independently in sexing of black Kenyan crania.", "pred_label": "__label__POS", "pred_score_pos": 0.8872039318084717}
{"content": "The U.S. Equal Employment Opportunity Commission (EEOC) has released for public comment proposed enforcement guidance\naddressing unlawful harassment claims brought under federal employment discrimination law. The guidance explains the legal standards applicable to such claims, which may be brought under laws protecting workers from discrimination based on race, color, religion, sex, national origin, disability, age, and genetic information.\nThe updates provided by the proposed enforcement guidance are intended to assist employers in efforts to prevent and address harassment in the workplace, an issue that was alleged in over thirty percent of all private sector charges of discrimination filed with the EEOC as recently as 2015.\n\"Harassment remains a serious workplace problem that is the concern of all Americans. It is important for employers to understand the actions they can take today to prevent and address harassment in their workplaces,\" said EEOC Chair Jenny R. Yang. Commissioner Chai R. Feldblum further explained, \"This guidance clearly sets forth the Commission's positions on harassment law, provides helpful explanatory examples, and provides promising practices based on the recommendations in the report.\"\nThe proposed enforcement guidance will be available for comment until February 9, 2017. Input may be submitted either electronically (via www.regulations.gov\n) or by sending written feedback to Public Input, EEOC, Executive Officer, 131 M Street, N.E., Washington, D.C. 20507. After reviewing the public input, the Commission will make further revisions to the proposed guidance before finalizing and publishing it.", "pred_label": "__label__POS", "pred_score_pos": 0.5754033923149109}
{"content": "How Often Can a Person File for an Increase in Child Support After the Divorce Is Final?\nBy Heather Frances J.D.\nGenerally, a judge orders child support payments in your divorce decree based on your family’s situation at the time of your divorce. Procedures vary according to state law, but courts can modify child support orders when a family’s situation changes, perhaps when one spouse receives a significant increase in income or the custody arrangements change.\nLimitations on Frequency\nMost states don’t have a specific limit on the number of times a parent can request an increase in support, but states often have rules that, practically speaking, limit the frequency of requests. Technically, you can file modification paperwork as often as you like, but filing does not mean your requests will be granted. Courts can continue to reject your filings if you do not qualify for a modification.\nSignificant Change of Circumstances\nTypically, courts grant motions to modify child support only if you or your ex-spouse have experienced a significant change of circumstances that affects your finances or care of your child. For example, if your ex-spouse receives a substantial pay raise, that raise may be considered a substantial change. Similarly, the court could consider it a significant change if your ex-spouse becomes disabled and cannot work. However, the court likely will not consider it a significant change if your ex-spouse marries a wealthy individual since the new spouse’s income is not generally included when calculating child support.\nRead More: What Is a \"Change in Circumstances\" in a Custody Case?\nPercentages\nSome states' statutes have a percentage threshold for when a modification is warranted. For example, Vermont considers a change substantial if the modified amount of child support, calculated using the state guidelines, would be at least 10 percent higher or lower than the previous amount. Arizona law allows a simplified modification procedure if the change is at least 15 percent, since that amount of change is presumed to be “substantial and continuing,” which is Arizona’s standard for modification.\nUsing State Calculations\nIf the child support terms in your divorce decree were not calculated according to your state’s guidelines, your state may allow you to ask for a modification to have this calculation done. However, calculation using the state guidelines may result in a decrease instead of an increase. If your state allows, you and your ex-spouse can also agree to a modification, even if it is not based on your state’s guidelines, and you may not have to go to court for a hearing since the court can simply adopt your agreement.\nReferences\nLegal Aid Services of Oklahoma: Modification of Child Support Q&A People’s Law Library of Maryland: Modifying Child Support Arizona Supreme Court: Child Support Modification in Arizona State of Vermont Supreme Court: Modification of Child Support Orders Colorado Legal Services: Frequently Asked Questions About Child Support California Courts: FL-350\nWriter Bio\nHeather Frances has been writing professionally since 2005. Her work has been published in law reviews, local newspapers and online. Frances holds a Bachelor of Arts in social studies education from the University of Wyoming and a Juris Doctor from Baylor University Law School.", "pred_label": "__label__POS", "pred_score_pos": 0.97686368227005}
{"content": "Dedicated guide to the lumbar plexus provides invaluable anatomicaland surgical insights Thorough knowledge of the lumbar plexus andits branches is crucial to achieving positive patient outcomes,especially with newer surgical approaches. Many of the nervebranches are formed within the psoas major muscle and carefuldissection is necessary to free them during surgery to preventdamage. Moreover, the iliac vessels are medial to some of thelarger branches of the plexus, such as the femoral and obturatornerves. In the retroperitoneal space, the kidney and ureter arenearby. In addition, due to the overlying peritoneal cavity and itscontents, accessing the lumbar plexus presents considerablechallenges. Surgical Anatomy of the Lumbar Plexus is the only bookon the market devoted to the lumbar plexus and its branches,focusing on anatomy and clinical applications, pathology, surgery,and imaging. Internationally known authors R. Shane Tubbs, MariosLoukas, Amgad Hanna, Rod Oskouian and a cadre of esteemedspecialists provide unique insights, clinical pearls, knowledgebased on thousands of spine surgeries, and a well-roundedmultidisciplinary perspective. Key Highlights Nine separatechapters dedicated to impacted nerves: subcostal, iliohypogastric,ilioinguinal, lateral femoral cutaneous, genitofemoral, femoral,obturator, furcal, and accessory obturator History and overview ofdermatomal anatomy of branches derived from the lumbar plexusAnesthetic blockade of the femoral, lateral femoral cutaneous,iliohypogastric, ilioinguinal, and genitofemoral nerves Tips forpreventing complications and achieving positive outcomes forlateral transpsoas approaches to the lumbar spine and otherprocedures More than 100 novel illustrations provide clarity andunderstanding of a complex anatomical area as it relates to surgeryinvolving the lumbar plexus and branches This one-of-a-kindresource provides crucial surgical and anatomical information onthe lumbar plexus. It is a must-have reference for neurosurgeons,orthopaedic surgeons, and general surgeons. Reading itcover-to-cover will ultimately benefit patients undergoing lumbarspine surgery. This book includes complimentary access to a digitalcopy on https://medone.thieme.com.\nGeneral\nIs the information for this product incomplete, wrong or inappropriate? Let us know about it.\nDoes this product have an incorrect or missing image? Send us a new image.\nIs this product missing categories? Add more categories.\nReview This Product\nNo reviews yet - be the first to create one!", "pred_label": "__label__POS", "pred_score_pos": 0.5245451927185059}
{"content": "Abstract\nNonsense-mediated mRNA decay (NMD) is an essential eukaryotic process regulating transcript quality and abundance, and is involved in diverse processes including brain development and plant defenses. Although some of the NMD machinery is conserved between kingdoms, little is known about its evolution. Phosphorylation of the core NMD component UPF1 is critical for NMD and is regulated in mammals by the SURF complex (UPF1, SMG1 kinase, SMG8, SMG9 and eukaryotic release factors). However, since SMG1 is reportedly missing from the genomes of fungi and the plant Arabidopsis thaliana, it remains unclear how UPF1 is activated outside the metazoa. We used comparative genomics to determine the conservation of the NMD pathway across eukaryotic evolution. We show that SURF components are present in all major eukaryotic lineages, including fungi, suggesting that in addition to UPF1 and SMG1, SMG8 and SMG9 also existed in the last eukaryotic common ancestor, 1.8 billion years ago. However, despite the ancient origins of the SURF complex, we also found that SURF factors have been independently lost across the Eukarya, pointing to genetic buffering within the essential NMD pathway. We infer an ancient role for SURF in regulating UPF1, and the intriguing possibility of undiscovered NMD regulatory pathways.", "pred_label": "__label__POS", "pred_score_pos": 0.9647407531738281}
{"content": "The acronym LED stands for Light Emitting Diode, an electric semiconductor device that transforms electric current into light. This form of illumination has various advantages over the traditional units. In case you're looking for the best lighting modifier for your photography venture, it's critical to consider it. For instance, in comparison to other types of brilliance, illuminators are the most power-saving and efficient. Other multiple benefits come with this type of lighting as listed and explained below:\nVariety of Colours and Intensities\nThe market has various choices for this form of illumination. You can, therefore, select a type of illuminator that suits your work and is compatible with your camera. You can either go for daylight or bi-color. Your eyes can't differentiate light from another, but your camera definitely will. Emitting diodes enables you to shoot shades that look better than in their natural form, thereby, saving you time for editing. Additionally, you can adjust the brightness of this form of lighting remotely. This enables you to control the brightness for your desired use. Emitting diode allows users to get outstanding and creative brilliance without using an extra gel.\nYou Can See the Lighting as You Prepare Your Shot\nUsing this form of illumination, you can see the required brilliance as you compose your shot. This allows you to adjust to the needed light instead of trial and error. In some cases, you can move closer to the subject for an outstanding shot when you use this kind of brightness. The flare produces less heat, which can't harm the subject or cause or discomfort.\nThey are Cool\nMost of us have experienced photo studio sessions where the room becomes unnecessarily hot because of the heat being emitted by the traditional glows. However, with Ring lights, the photographer and their subjects don't have to endure the discomforting heat. The serene nature of the radiance keeps the studio comfortable for the photographer and their clients. This form of brightness can also be put in strategic places like corners where the traditional glow forms may be hazardous. Plus, gels can be attached to them without melting, meaning that there is no time required to cool down after finishing a session. This saves you time.\nUninterrupted Change From Photo to Video\nIn some cases, you may need to shoot both pictures and videos in a scene. With an LED light kit, you can effortlessly do that without any extra equipment. Uninterrupted illumination is essential for video shooting. Adjusting your glow to suit a portrait lighting for still photos and the video scene enables you to work with a less complicated setup of equipment.\nConsumption of minimal Power\nIn contrast to standard forms, LED glow tools are energy-efficiency. They can save proximately between 80% and 90%. This is a considerable decrease in energy use. This implies that approximately 90% of power is turned into a useful application. This form of brilliance also is not only environmentally-friendly but saves a lot of resources.\nIt doesn't have any harmful chemicals compared to the traditional studio glow tools gadgets. For instance, many conventional fluorescent tubes contain mercury, a substance that is an environmental hazard. Furthermore, LED lights have no harmful materials and can be recycled. This decreases carbon emission and saves the ecology.\nFlexible\nThis form of brilliance can function in multiple environments and setups. For instance, they can work well at lower temperature environments as well as harsh weather conditions. They can perform perfectly well even in fridges and freezers. Illuminators lighten up as soon as you switch them on. They don't require time to warm up before brightening like the traditional lights.\nYou can turn them on and off regularly. This doesn't affect the tool's life span or amount of light produced. This is a great advantage since the conventional lights can't withstand constant switching on and off.\nLess Voltage is Needed\nThey require a minimal power supply to work. This feature enables you to work in the outsides by plugging it to solar energy. This also comes in handy when you are shooting in a remote or rural area where there is no power supply.\nLED's are Durable\nMost of the traditional lighting systems have less life span compared to LEDs. Whereas LED can last for more than 15 years, other arrangements can last for less than two years. This means that investing in the LED glow is cost-effective. They require little to no maintenance. This makes them cost-effective and environmentally friendly since they are not disposed of frequently.\nMaterials are of High Quality\nUnlike the standard systems that are made from low-quality stuff, LED brilliance manufactured from high-quality plastic materials that are resistant to shocks and breaking. They are powerful can be used in various scenarios.\nProduce Uniform illumination\nThis form of illumination is made in such a way that it focuses on the subject with minimal reflections. You don't need to purchase additional reflectors when you've got this kind of This light can be targeted to the direction of the subject without other mirrors. With this, you get uniform lighting and therefore save you time in terms of editing.\nPurchase LED Ring Light\nIn case you want to take your photography business to the next level, it is advisable to invest in LED ring light. The tool is of top-notch quality and offers the best and focused images.\nKey takeaways\nHaving LED photography brilliance is the best step to take when you want to elevate your venture. This kind of brilliance displays professionalism in your work and saves you a lot of time in editing. The equipment is also eco-friendly and cost-effective.", "pred_label": "__label__POS", "pred_score_pos": 0.5225462913513184}
{"content": "In apartment buildings, roof extraction units are often necessary to ensure clean, high-quality indoor air. Ventilation in apartment buildings is often set at a default level, even though the load varies. This results in a significant loss of energy. Ventilation applications in apartment buildings are easy to implement by using HK Instruments’ measurement devices. Our cost-efficient solutions do not need to be supported by an expensive building automation system", "pred_label": "__label__POS", "pred_score_pos": 0.9999980926513672}
{"content": "My lab's overall research goal is to understand and investigate the cellular and immunological mechanisms underlying the initiation and progression of synucleinopathy disorders. Specifically, my lab research focuses on how the protein alpha-synuclein contributes to microglial activation, peripheral immune cell infiltration, and subsequent activation of the immune response in Parkinson disease (PD) and Multiple System Atrophy (MSA) models. In the lab we work with multiple immune cell types, including myeloid cell subsets and T cells to pursue research regarding these mechanisms. Therapeutic strategies targeting and blocking immune system activation have been neuroprotective, however, differentially targeting immune cell subsets in the central nervous system (CNS), specifically microglia, without undesirable effects on extra-CNS immunity has been a challenge. By combining transgenic animals with an alpha-synuclein viral models of PD and MSA to study the role of immune cells subsets, we aim to dissect mechanisms of immune-mediated disease pathogenesis in synucleinopathy disorders.", "pred_label": "__label__POS", "pred_score_pos": 0.6200536489486694}
{"content": "The U.S. Centers for Disease Control and Prevention (CDC) has created extensive resources related to Coronavirus Disease 2019 (COVD-19). The vastness of these resources can also make it challenging for real estate owners, managers, and operators to quickly find the information they need.\nSome of the most common questions related to COVID-19 deal with building cleaning and disinfection. The CDC has released interim recommendations for environmental cleaning and disinfection for buildings and facilities with suspected and confirmed COVID-19 cases. These recommendations include how to clean and disinfect, and information on specific cleaning products, as well as additional considerations for employers.\nThe CDC Interim Guidance for Businesses and Employers webpage also includes guidance for employers to conduct routine environmental cleaning.\nThe Occupational Safety and Health Administration (OSHA) also outlines information on environmental decontamination on its COVID-19 Control and Prevention webpage.\nThe Building Owners and Managers Association (BOMA) of Georgia Foundation has also released a free one-page guide to resources for commercial real estate professionals to consider in maintaining a healthy building environment. The resources relate specifically to COVID-19 and infectious disease control in general.", "pred_label": "__label__POS", "pred_score_pos": 0.8587796092033386}
{"content": "Type of Activity: Project Grant Grantee: CSME Action, a project of Sixteen Thirty Fund Amount: $1,000,000 in 2019 over two years What is CSME Action?\nCenter for Secure and Modern Elections (CSME) Action, a project funded by Sixteen Thirty Fund, works to make voting registration easier through pro-voter policy reform advocacy. They are a bipartisan organization dedicated to advancing pro-voter policies at the state level that modernize the voting process and ensure that every eligible voter can have their voice heard. CSME Action supports state-led efforts to defeat bad policies and rules, pivot to strong pro-voter policies, and change the conversation so that both parties engage in pro-voter activities.\nWhy do we think this project is important?\nCSME Action has extensive expertise in advocating for pro-voter legislation and defending existing voting policies from detrimental changes.\nThey advance pro-voter reforms through different strategies, including providing assistance to local leaders who want to modernize their elections for the 21st century — regardless of party affiliation. They also provide resources to support the efforts of organizations and advocates who elevate the voices of individuals negatively impacted by voting registration policies. Because there is a wide range of needs unique to different regions and communities, CSME Action works with community members to identify the right modernization policies for a specific state. This customized approach builds buy-in from local leaders and community members, and ensures that chosen reforms will be the most effective option.\nHow is Democracy Fund Voice supporting CSME Action?\nIn 2019, Democracy Fund Voice approved a grant of $1,000,000 over two years to Sixteen Thirty Fund to support the Center for Secure and Modern Elections (CSME) Action.", "pred_label": "__label__POS", "pred_score_pos": 0.8683628439903259}
{"content": "MEDIA RELEASE\n(October 7, 2019) – Hawaii gas prices have risen 3.0 cents per gallon in the past week, averaging $3.86/g today, according to GasBuddy’s daily survey of 355 stations. Gas prices in Hawaii are 4.0 cents per gallon higher than a month ago, yet stand 21.1 cents per gallon lower than a year ago.\nAccording to GasBuddy price reports, the cheapest station in Hawaii is priced at $3.21/g today while the most expensive is $4.49/g, a difference of $1.28/g. The lowest price in the state today is $3.21/g while the highest is $4.49/g, a difference of $1.28/g. The cheapest price in the entire country today stands at $1.89/g while the most expensive is $5.52/g, a difference of $3.63/g.\nThe national average price of gasoline has risen 0.3 cents per gallon in the last week, averaging $2.65/g today. The national average is up 9.6 cents per gallon from a month ago, yet stands 25.3 cents per gallon lower than a year ago.\nHistorical gasoline prices in Hawaii and the national average going back a decade:\nOctober 7, 2018: $4.07/g (U.S. Average: $2.91/g) October 7, 2017: $3.30/g (U.S. Average: $2.48/g) October 7, 2016: $2.84/g (U.S. Average: $2.26/g) October 7, 2015: $2.86/g (U.S. Average: $2.29/g) October 7, 2014: $4.17/g (U.S. Average: $3.27/g) October 7, 2013: $4.21/g (U.S. Average: $3.33/g) October 7, 2012: $4.38/g (U.S. Average: $3.82/g) October 7, 2011: $4.23/g (U.S. Average: $3.38/g) October 7, 2010: $3.41/g (U.S. Average: $2.76/g) October 7, 2009: $3.28/g (U.S. Average: $2.44/g)\nNeighboring areas and their current gas prices:\nAlaska- $2.97/g, down 4.7 cents per gallon from last week’s $3.02/g. Anchorage- $2.83/g, up 0.6 cents per gallon from last week’s $2.82/g.Honolulu- $3.52/g, unchanged from last week’s $3.52/g.\n“It was a mixed bag for gas prices over the last week even as oil prices remained relatively low. California continued to lead the nation as prices skyrocketed, but appear to have peaked for now, while the Great Lakes states also saw prices march higher due to a price cycle. Other states saw some downward movement, but we appear ripe for a week that features more price decreases than increases, especially for hard-hit California,” said Patrick DeHaan, head of petroleum analysis for GasBuddy. “I believe we’re due for the national average to edge lower by perhaps five cents in the coming week as I believe increases should be limited due to oil’s drop in the last week fueled by continued worry over tariffs and trade, not with just China but now extending to Europe after the WTO agreed with the U.S. that Airbus was getting favorable treatment. Many motorists may scoff at such an issue affecting gas prices, but indeed, the threat of tariffs between such large trading partners is a serious issue that could result in slowdowns in both areas, leaving demand for oil lower and thus weighing on oil prices as a result.”\nGasBuddy is the authoritative voice for gas prices and the only source for station-level data spanning nearly two decades. Unlike AAA’s once daily survey covering credit card transactions at 100,000 stations and the Lundberg Survey, updated once every two weeks based on 7,000 gas stations, GasBuddy’s survey updates 288 times every day from the most diverse list of sources covering nearly 150,000 stations nationwide, the most comprehensive and up-to-date in the country.\nFor Hawaii Island gas prices and trends visit — www.hawaii247.com/gas", "pred_label": "__label__POS", "pred_score_pos": 0.702690601348877}
{"content": "SPRINGFIELD — The Provider’s Council, an association of community-based human-services agencies in Massachusetts with more than 220 members, annually recognizes extraordinary accomplishments of member agencies through its Peer Provider Awards. Agencies must be nominated for the award by another Providers’ Council member.\nFor 2020, MHA received a Peer Provider Award recognizing innovation in programming and services, including the GRIT residential rehabilitation program, TeleWell telemedicine service delivery, and the BeHealthy Partnership to address mental health and homelessness concurrently. Ruth Banta, executive director of Pathlight, a Springfield-based nonprofit that partners with people with disabilities, nominated MHA for the Peer Provider Award.\n“We are thrilled that the Mental Health Association has been recognized by a peer organization for a prestigious Providers’ Council Peer Provider Award for 2020,” said Michael Weekes, president and CEO of the Providers’ Council. “MHA plays a crucial role in providing critical services to residents in Western Massachusetts. MHA’s BeHealthy Partnership initiative has been pivotal in improving outcomes for numerous clients who are experiencing homelessness throughout the region. MHA’s commitment to excellence has earned them the respect and admiration of many in the human-services community, and the Providers’ Council is honored to bestow this award.”\nCheryl Fasano, president and CEO of MHA, noted that “it’s an extraordinary testament to MHA’s work when a peer provider, and the leaders of a 220-member organization of providers, all recognize the growth, impact, and influence of our work. We are proud of our ability to continue identifying community needs and responding with the development of new programming, even in the current environment. This award is for the people of MHA who identify areas of need, who innovate by creating new programs and services, and who provide direct care to the people we serve every hour of every day.”\nAdded Banta, “I think it is important to consider that MHA is a 60-plus-year-old organization that built its widely respected reputation for respect, integrity, and compassion in the area of residential programming for people with developmental disabilities. While that focus indeed continues, it is significant that MHA has the vision, people, and capabilities to diversify its portfolio of programming by developing new ways to serve, including GRIT residences, TeleWell service, and the Home Healthy program. Rather than rest on its laurels, MHA instead chooses to create innovative ways to serve vulnerable populations. MHA continues to break new ground. We at Pathlight value our collaborations with MHA.”", "pred_label": "__label__POS", "pred_score_pos": 0.9741573333740234}
{"content": "Strong, healthy bones need boron, but this mineral can be challenging for the body to absorb. Swanson Boron from Albion's Bororganic Glycinate optimizes absorption and bioavailability to ensure effective supplementation. Albion is the leader in high-absorption minerals, producing unparalleled dietary minerals you can trust. Each capsule delivers 6 mg of boron.", "pred_label": "__label__POS", "pred_score_pos": 0.9974955320358276}
{"content": "In a November 14 speech before the Financial Executives International (FEI) 36th Annual Financial Reporting Issues Conference, SEC Chief Accountant Wesley Bricker, called on the accounting profession to \"light a lamp\" to understand distributed ledger, i.e., blockchain, technology, and its impact on financial reporting. He noted that the SEC's Office of the Chief Accountant (OCA) is doing similarly, and \"with a compass; namely the Commission's existing accounting and auditing requirements, books and records requirements, auditor independence rules, and the federal securities laws more generally\". Referring to these things collectively as a \"framework,\" Bricker urged the profession to invest the time to understand the impact of new technologies on commerce and financial reporting within the current framework, even though those rules predate the development of recent technologies such as blockchain.", "pred_label": "__label__POS", "pred_score_pos": 0.9999402761459351}
{"content": "Emplacement\nOver a billion people worldwide, predominately smallholder farmers, lack secure land rights, which are crucial for obtaining loans and providing the long-term visibility necessary for planning successful agricultural operations. Open data technologies enable mapping and access to information on land rights, which in turn can lead to more protection for community and smallholder farmers.", "pred_label": "__label__POS", "pred_score_pos": 1.0000052452087402}
{"content": "Most arrests for drunk driving occur after a traffic stop. The officer initiates a traffic stop, detects signs of intoxication, conducts field sobriety tests, and typically concludes with a preliminary breath test (“PBT”). If the driver has consumed enough alcohol that a PBT demonstrates his or her blood alcohol content (“BAC”) is over the legal limit, the officer will arrest the driver for drunk driving. Upon reaching the police station, the driver will be subjected to additional breath tests, using a more sophisticated equipment.\nGiven the amount of evidence created in this chain of events, a successful defense is challenging. However, there are several key events occurring during the arrest which can be attacked. This blog focuses solely on the traffic stop itself, which implicates the Fourth Amendment constitutional right to be free from unreasonable searches and seizures.", "pred_label": "__label__POS", "pred_score_pos": 0.9998671412467957}
{"content": "Principles of servant leadership\nScripture provides the foundation for understanding the function of servant leadership, an essential blueprint for all those practicing leadership in the church. Scripture shows that all members of the church - clergy and laity - are under the authority of the written commandment, bound by duty and personally accountable to its directive for the community.\nWhen we consider servant leadership from a biblical perspective, humility and authority are critical. As a servant leader, what does it mean to be humble? As a servant leader, what does it mean to exercise authority? And what does it look like when we do both? To be a servant leader is to live in obedience to the commandments of Jesus Christ, and to exercise Christlike authority and humility no matter what our station.", "pred_label": "__label__POS", "pred_score_pos": 0.703299880027771}
{"content": "2014’s Auto Defect Recalls to Double the Previous Yearly Record\nAs many can surmise from the stream of bad news flowing from Detroit and Japan, 2014 was not a good year for auto-manufactures, vehicle parts suppliers, federal regulators or for the consumers who drive the vehicles manufactured by the major automakers. Auto manufacturers reputation for producing safe vehicles took severe hits due to fallout from continued safety problems — like Toyota’s unintended acceleration glitch — and the new 2014 safety defects that includes the GM ignition switch recall and Takata airbag defect. Likewise, parts suppliers like Delphi and Takata found themselves uncomfortably under the spotlight also due to the same vehicle problems. Federal regulators were also burned several times by standing by the companies the agency is supposed to regulate only to discover that these companies may have withheld information or provided incomplete safety testing data. This situation has resulted in the realization for many motorists that they and their family may not be as safe in their vehicle as the manufacturer claims.\nThe Expanded Takata Airbag Recall\nLast week automaker FCA (formerly Fiat and Chrysler, respectively)announced the expansion of its Takata airbag recall from being limited to the nearly 400,000 vehicles in high-humidity climates, to a nation-wide recall that will impact approximately 3.3 million vehicles. The announcement saw FCA join Ford, Honda, others who also announced an expanded Takata airbag recall. Affected FCA cars and trucks include vehicles produced between the years 2004 and 2007 and includes the following models:\nDodge Magnum station wagons Dodge Ram 1500, 2500 and 3500 pickups Dodge Ram 3500 Chassis Cabs Mitsubishi Raider pick-ups Dodge Durango SUVs Chrysler Aspen SUVs Chrysler 300 sedans Dodge Charger sedans Dodge Dakota pickups\nHowever, in a public statement, the company made clear that no particular instance of the defect had been discovered in the products affected by the recall, but the recall was being ordered due to an abundance of caution. The statement, in part, stated “Neither FCA US nor Takata Corporation, the supplier, has identified a defect in this population of inflators. These components also are distinct from Takata inflators cited in fatalities involving other automakers. More than 1,000 laboratory tests have been performed on these components. All deployed as intended, but FCA US continues to study the suspect inflators, which are not used in the Company’s current production vehicles.”\nChrysler has stated that it will still prioritize areas where high humidity is present, but it will provide parts for all affected owners. These measures, however, may be complicated by Takata Corporation’s failure to, itself, expand the recall despite pressure from National Highway Traffic Safety Administration (NHTSA) and legislators.\nIgnition Switch Defect, Exploding Airbags Leading Reasons for Auto Recall Record in 2014\nThe previous auto-recall record was set in 2004 when approximately 30.8 million vehicles were recalled by NHTSA. As of Saturday, December 20\nth, there had been more than 60 million auto safety recalls in 2014. In light of the date of the tally where more than 10 days remain in the year, it is extremely likely that the total will continue to increase. This tally not only sets the record for auto recalls in a single year, it also marks the first time in history the safety recalls have surpassed 60 million vehicles. While many auto safety issues have contributed to this total, the GM ignition switch recall and the Takata recalls are, by far, the largest. Other contributions to the record include: GM ignition switch recall– The GM ignition switch recall resulted in at least 71 separate recall notices that impacted nearly 27 million vehicles in the United States. The Delphi-produced ignition switches affected vehicles including many of GM’s most popular models, Chevrolets, Buicks, Cadillacs, and many other vehicles. The GM ignition switch recall may fundamentally change NHTSA’s approach to auto safety as this debacle showed that early warning reporting (EWR) was not effective as currently implemented. Toyota unintended acceleration defect– While the Toyota defect was first reported back in 2009, it has continued to plague the automaker. An additional recall was announced in September 2014 due to “low-speed surging” present in Toyota Corollas produced between 2006 and 2010 equipped with a throttle-control system called ETCS-i. Takata exploding airbag defect– While this recall was initially limited to only those areas with a high relative humidity, the recall has been expanded to cover the entire nation. The injuries produced by this particular defect can be both fatal and gruesome. In several instances of this defect, police initially suspected a violent attack on the driver due to the severe lacerations to the face and neck caused by the exploding airbag. Vehicles potentially equipped with defective, exploding Takata airbags include those produced by Acura, BMW, Dodge, Ford, Honda, Lexus, Nissan, Saab, Subaru and many others. Trinity ET-Plus Guardrails– While this is not strictly a vehicle defect, the unapproved and unreported changes that were made to these guardrail parts nevertheless affect the safety of motorists. Further, this incident reflects the ineffectiveness of federal regulators who are deferential and accept the explanations and justifications to the companies they are overseeing at face value.\nThe foregoing captures only the largest of the numerous vehicle defects that contributed to 2014’s new record for vehicle safety recalls. There were many other auto safety problems, like the nearly 500,000 vehicles recalled by Volkswagen due to a defect that could result in loss of control, that would have received greater attention if not for the massive GM and Takata recalls.\nWill 2015 Bring Improved Vehicle Safety To Us Drivers?\nPredictions are always difficult. However, if we look towards trends and attitudes in how auto safety and vehicle recalls are likely to be handled we can draw some conclusions. In essence, whether 2015 will bring improvements to auto safety for American consumers will largely be dependent on the political winds in Washington. If public pressure and the political will is maintained, it is likely NHTSA will continue on its course towards demanding greater accountability and providing reduced deference to auto manufacturers.\nIn a scenario where improving auto safety and correcting the slow defect response times remains in focus, NHTSA is likely to continue wielding its subpoena power and its other investigative and enforcement tools. We should note that if NHTSA continues or expand its renewed commitment to asking tough questions of manufacturers, recall numbers may continue to increase. However, these short-run increases in raw recall numbers will undoubtedly be justified by removing unsafe vehicles from the roadways through both present actions and through the heightened regulatory expectations. However, should auto safety concerns again fade to the background it is conceivable that federal regulators could return to a more deferential approach like the one initially utilized in Takata airbag recall and the Trinity ET-Plus guardrail recall? The safest conclusion to draw from auto safety in 2014 is that public outrage over safety concerns and public interest in the process can have a real impact and can affect how federal officials in Washington approach their job.", "pred_label": "__label__POS", "pred_score_pos": 0.6286016702651978}
{"content": "I am a longtime worker’s rights advocate. As a Board Certified labor and employment lawyer, I’ve spent my legal career fighting for employees and labor unions.\nA Houston native, I was raised in a union family, by a father who was a member of the Communications Workers of America, AFL-CIO, and a mother who was a member of the Houston Federation of Teachers, AFL-CIO.\nI graduated with Sociology and Political Science degrees from Texas Tech University before attending graduate school at North Carolina State University with the intention of becoming a sociology professor. While in graduate school, I grew increasingly passionate about workers’ rights but frustrated with the lack of opportunities for creating real change within academic Sociology. With these lessons learned, I obtained my Masters of Sociology degree, hightailed it back to Texas, and attended law school at Texas Tech University School of Law. During law school, I clerked for HFT and Texas Rural Legal Aid, a fantastic non-profit law firm that provides free employment representation to migrant farmworkers.\nSince becoming a lawyer in 2003, I have devoted my legal career to representing employees in employment disputes and labor unions in labor disputes, with the exception of a brief stint as a plaintiff-side personal injury lawyer representing mesothelioma victims. I learned the tools of the trade from Janette Johnson, a pioneer in plaintiff-side employment law, as well as Rod Tanner, a top labor and employment lawyer in Fort Worth. I started my own practice in 2009, and added a law partner, Kyla Cole, in 2016.\nToday, I’m honored to represent employees in employment disputes and labor unions in labor disputes. My largest union client is Alliance-AFT, the largest teacher’s union within Dallas ISD. Through this union, I proudly represent teachers in termination and non-renewal proceedings before the Texas Education Agency. I have also been retained by Transport Workers Union Locals 549 (American Airlines SIM Pilot Instructors), 567 (American Airlines mechanics at Alliance Airport), and 748 (American Airlines Dispatchers) for various labor disputes. I’ve also performed work for Southwest Airlines Pilots Association (SWAPA), an independent union that represents the pilots at Southwest Airlines, HFT (teachers and paraprofessionals within Houston ISD), and Cy-Fair AFT (teachers and paraprofessionals within Cy-Fair ISD).\nIn my free time, I enjoy cooking and spending time with my wonderful significant other, who is a police officer with the Dallas Police Department.", "pred_label": "__label__POS", "pred_score_pos": 0.8425151109695435}
{"content": "Textile exporters in Pakistan have urged the government to support its value-added textile chain by focusing on cotton production, cultivation area and yield, reports Tribune.\nAs per Pakistan Cotton Ginners Association (PCGA), the country produced only 4.02 million bales till November 15, 2020, as compared to 6.85 million bales produced during the same period of last year. The major causes of this decline R: reduction in cultivation area and per acre production, low-quality seeds and shifting of farmers’ focus towards other crops due to a lack of government support. Production shortfall has had a devastating impact on Pakistan’s textile exports compelling exporters to seek government aid.\nMuhammad Jawed Bilwani, Chairman, PCGA has requested the government to allow import of cotton yarn without customs and regulatory duty under the current sMutate of affairs as it had already permitted duty-free import of cotton.", "pred_label": "__label__POS", "pred_score_pos": 0.9330101609230042}
{"content": "An increasingly complex and diverse collection of Machine Learning (ML) models as well as hardware/software stacks, collectively referred to as ‘ML artifacts’, are being proposed - leading to a diverse landscape of ML. These ML innovations proposed have outpaced researchers' ability to analyze, study and adapt them. This is exacerbated by the complicated and sometimes non-reproducible procedures for ML evaluation. A common practice of sharing ML artifacts is through repositories where artifact authors post ad-hoc code and some documentation, but often fail to reveal critical information for others to reproduce their results. This results in users' inability to compare with artifact authors' claims or adapt the model to his/her own use. This paper discusses common challenges and pitfalls of ML evaluation and benchmarking, which can be used as a guideline for ML model authors when sharing ML artifacts, and for system developers when benchmarking or designing ML systems.", "pred_label": "__label__POS", "pred_score_pos": 0.9931136965751648}
{"content": "This is number 50 of the Mediterranean Science Commission (CIESM) monographs series, it opens perspectives on the lessons to gain on all sides by forging new alliances between marine researchers and fishermen.\nImpacts of human activities on marine biodiversity are extensively studied. However, the opposite, i.e. the impacts of marine biota on human activities, are far less considered. Yet, if biodiversity is widely regarded as favourable for human activities, certain species may also negatively impact human well-being, through direct and indirect effects.\nTo explore this complex subject, experts of various geographic horizons and backgrounds were invited by the CIESM at the Oceanographic Institute in Paris, in April 2018. The objectives of the workshop emphasized the need to include a broad marine socio-ecosystem vision when considering the interferences of marine biota and human activities. This monograph was developed on the basis of written contributions provided by the participants of this workshop.\nCIESM (2018) Engaging marine scientists and fishers to share knowledge and perceptions – Early lessons. CIESM Workshop Monograph n° 50 [F. Briand, Ed.] CIESM Publisher, Monaco, 218 p.", "pred_label": "__label__POS", "pred_score_pos": 0.9871331453323364}
{"content": "Join the Alumni Association for a series of leadership sessions to help Redbirds develop and expand their tool kits. These sessions are designed for all alumni to learn key takeaways to implement in their workspaces.\nMost of us think that “office politics” are bad and that political behavior is harmful to organizations. Some behavior that we consider political— backstabbing, deviousness, dishonestly, etc.—is wrong and can harm organizations.\nHowever, not all political behavior in organizations is devious and wrong. In fact, not only is political behavior a normal aspect of social systems, but it also can play a vital role in productive organizational outcomes. This session will provide participants with a much deeper and useful understanding of political activity in organizations as well as insights regarding how they can enhance their own individual political acumen.\nWhen: noon–1 p.m. (CST), Tuesday, December 8 Where: Join via Zoom on any mobile device or computer\nThis is a complimentary event but advance registration is required due to limited space. Please\nregister online until December 8 or until capacity is reached.", "pred_label": "__label__POS", "pred_score_pos": 0.5669634342193604}
{"content": "Kidney transplant recipients have been reported at a particularly high risk of severe COVID-19 illness due to chronic immunosuppression and coexisting conditions. Yet, here we describe a remarkably mild case of COVID-19 in a 62-year-old female who had a kidney transplantation 10 years earlier due to autosomal dominant polycystic kidney disease. The patient was admitted for 1 day; immunosuppressive therapy with tacrolimus and low-dose prednisolone was continued; and the patient recovered successfully without the use of antiviral agents or oxygen therapy. The case demonstrates that kidney transplant recipients are not necessarily severely affected by COVID-19. Withdrawal of immunosuppressive therapy could be associated with poorer outcomes and should not be implemented thoughtlessly.", "pred_label": "__label__POS", "pred_score_pos": 0.9973832964897156}
{"content": "Most drivers have likely had an experience in which they have forgotten to turn on their headlights while driving. While this is typically a relatively minor issue, a woman in Wisconsin now faces OWI allegations after a traffic stop. The woman reportedly remained hospitalized in the days following the incident after she was injured during it.\nAn officer with Wisconsin State Patrol claims he noticed a driver driving without headlights during the early morning hours of a day in late June. The officer claims that he attempted a stop. However, the driver continued heading south, ultimately turning the wrong way on an interstate off ramp.\nOnce the driver stopped, the officer claims that the 39-year-old driver appeared to be intoxicated; however, it is unclear what led to the officer to this assumption. The woman reportedly fell during a field sobriety test. She was transported to the hospital as a result where a blood draw was taken. She remained hospitalized so her medical condition could be evaluated, but she is suspected of a seventh offense for operating a vehicle while under the influence of intoxicants or drugs.\nSome people may find themselves suffering from a medical condition with symptoms that may resemble intoxication. Even when a person has a history of OWI issues, there must be sufficient evidence to prove guilt beyond a reasonable doubt for a person in Wisconsin and across the country to be convicted of criminal charges. Because the consequences of a conviction can be severe, most people facing such accusations want an experienced criminal defense attorney on their side.", "pred_label": "__label__POS", "pred_score_pos": 0.7699990272521973}
{"content": "We all know how disturbing it can be: that moment when someone steps out in front of a vehicle. Or, you’re driving along the freeway and a truck in front of you suddenly swerves. At such moments, we rely on two things: our own instincts and experience, and the brakes on our car.\nIf your brakes are pulling or vibrating when you press on them, or if they are making grinding or squealing noises when they’re applied – then this is a sign that it’s time to let our Toyota, Lexus or Scion repair teams, here at Toy Car Care, take a look. This is one key driving area where it doesn’t make sense to say ‘later’; it could be too late!", "pred_label": "__label__POS", "pred_score_pos": 0.7938510775566101}
{"content": "G Meter, popularly known as accelerometer is an electromechanical device used for measuring acceleration forces which are either static or dynamic. Static forces includes gravity and dynamic forces include movements and vibrations. The acceleration can be determined with the capacitive plate movement among each other. Additionally, G meters are also used for measuring shocks. It helps in identifying how quickly an object can speed up and slow down in a given time frame. G meters have a significant use in aerospace and defense industry for inertial navigation and guidance systems. There are multiple ways for functioning of accelerometers including piezoelectric effect and capacitance sensing among others.\nFurthermore, G meters are available in analog and digital formats depending on the interface provided by the device. Within aerospace industry the G meter is used to register the ‘g’ force on the airframe during turbulent or aerobatic maneuvers. The unit of measurement for G meters are meters per second squared (m/s2) or in G-forces (g). G meters can measure accelerations in one, two or three axes.\nThe significant use of G meters in civil and aerospace applications are suggested to be one of the primary reasons for the growth of the G meters over the forecast period. High frequency response and durable construction of these devices are also one of the significant factors which are having a positive impact on the global G Meters market for the same. However, the significant cost for G meters is one of the factors which can hinder the growth of its global G meters market.\nAdditionally, integration of G meters with MEMS (Microelectromechanical Systems) is suggested to boost the global G meters market over the forecast period. The reducing size of the G meters are making it an optimal option for a wide range of applications including drones, micro robots and various military applications.\nThe global G meters market can be divided into four segments namely type, dimension end use industry and region. As per type, the global G meters market can be divided into piezoelectric, piezoresistive and MEMS. By type, the MEMS sub segment is anticipated to hold a significant share for the global G meters market over the forecast period. Furthermore, as per dimension the global G meters market is divided into single axis, two axis and three axis. The three axis is suggested to grow at a significant scale owing to its wider scope of applications. As per end use industries the global G meters market is divided into six sub segments namely – consumer electronics, aerospace and defense, transportation, automotive, healthcare and others.\nThe consumer electronics and aerospace and defense industry are suggested to play a crucial role in the global G meters market over the forecast period owing to its significant adoption. As per the regional segment the G meters market can be divided amongst five regions namely North America, Europe, Asia Pacific, Middle East and Africa and South America. Owing to its prominent presence in the consumer electronics industry Asia Pacific and North America are anticipated to hold a prominent share of the G meters market.\nOwing to its significant adoption in multiple application, the G meters market is consisting of multiple leading players. Some of the major players are Murata Manufacturing Co., Ltd., Honeywell International, Inc., NXP Semiconductors N.V., Analog Devices Inc., Colibrys Ltd., TDK InvenSense, KVH Industries, Inc, Northrop Grumman, Robert Bosch GmbH and STMicroelectronics N.V. among others\nThis study by TMR is all-encompassing framework of the dynamics of the market. It mainly comprises critical assessment of consumers' or customers' journeys, current and emerging avenues, and strategic framework to enable CXOs take effective decisions.\nOur key underpinning is the 4-Quadrant Framework EIRS that offers detailed visualization of four elements:\nCustomer Experience Maps Insights and Tools based on data-driven research Actionable Results to meet all the business priorities Strategic Frameworks to boost the growth journey\nThe study strives to evaluate the current and future growth prospects, untapped avenues, factors shaping their revenue potential, and demand and consumption patterns in the global market by breaking it into region-wise assessment.\nThe following regional segments are covered comprehensively:\nNorth America Asia Pacific Europe Latin America The Middle East and Africa\nThe EIRS quadrant framework in the report sums up our wide spectrum of data-driven research and advisory for CXOs to help them make better decisions for their businesses and stay as leaders.\nBelow is a snapshot of these quadrants.\n1. Customer Experience Map\nThe study offers an in-depth assessment of various customers’ journeys pertinent to the market and its segments. It offers various customer impressions about the products and service use. The analysis takes a closer look at their pain points and fears across various customer touchpoints. The consultation and business intelligence solutions will help interested stakeholders, including CXOs, define customer experience maps tailored to their needs. This will help them aim at boosting customer engagement with their brands.\n2. Insights and Tools\nThe various insights in the study are based on elaborate cycles of primary and secondary research the analysts engage with during the course of research. The analysts and expert advisors at TMR adopt industry-wide, quantitative customer insights tools and market projection methodologies to arrive at results, which makes them reliable. The study not just offers estimations and projections, but also an uncluttered evaluation of these figures on the market dynamics. These insights merge data-driven research framework with qualitative consultations for business owners, CXOs, policy makers, and investors. The insights will also help their customers overcome their fears.\n3. Actionable Results\nThe findings presented in this study by TMR are an indispensable guide for meeting all business priorities, including mission-critical ones. The results when implemented have shown tangible benefits to business stakeholders and industry entities to boost their performance. The results are tailored to fit the individual strategic framework. The study also illustrates some of the recent case studies on solving various problems by companies they faced in their consolidation journey.\n4. Strategic Frameworks\nThe study equips businesses and anyone interested in the market to frame broad strategic frameworks. This has become more important than ever, given the current uncertainty due to COVID-19. The study deliberates on consultations to overcome various such past disruptions and foresees new ones to boost the preparedness. The frameworks help businesses plan their strategic alignments for recovery from such disruptive trends. Further, analysts at TMR helps you break down the complex scenario and bring resiliency in uncertain times.\nThe report sheds light on various aspects and answers pertinent questions on the market. Some of the important ones are:\n1. What can be the best investment choices for venturing into new product and service lines?\n2. What value propositions should businesses aim at while making new research and development funding?\n3. Which regulations will be most helpful for stakeholders to boost their supply chain network?\n4. Which regions might see the demand maturing in certain segments in near future?\n5. What are the some of the best cost optimization strategies with vendors that some well-entrenched players have gained success with?\n6. Which are the key perspectives that the C-suite are leveraging to move businesses to new growth trajectory?\n7. Which government regulations might challenge the status of key regional markets?\n8. How will the emerging political and economic scenario affect opportunities in key growth areas?\n9. What are some of the value-grab opportunities in various segments?\n10. What will be the barrier to entry for new players in the market?\nNote: Although care has been taken to maintain the highest levels of accuracy in TMR’s reports, recent market/vendor-specific changes may take time to reflect in the analysis.", "pred_label": "__label__POS", "pred_score_pos": 0.9781254529953003}
{"content": "One theme that struck me in the research phase is that many people in the 50 - 65 age group are considering downsizing their homes. It made me think. How much support do they get when they are considering downsizing?\nI also noted that it was reported that some people had downsized their homes but their spending increased. This could be due to a number of factors. For example, if someone moves from a city to the countryside they may have to travel further to entertainment centres, their doctor or their bank increasing their transportation costs.\nIs there a need for an app, website or in-person service to help people make an informed financial decision on whether to downsize or not? Is there a need for a tool to help people set and stick to a budget after they downsize? Is there a need for a tool to help them plan and co-ordinate the actual act of downsizing?\nWhat information would you need from the 50 - 65 year olds to help them make an informed decision e.g. habits and house information?\nIs there a need to link to websites or information sources e.g. real estate websites or form affiliations to other companies e.g. real estate lawyers?\nWhat other pieces of information would be needed e.g. typical costs for removal vans?\nDo you think there is a need for this services/tool?\nI would really like someone in the OpenIDEO community to build on this idea if it resonates with them. I am unable to develop this idea.", "pred_label": "__label__POS", "pred_score_pos": 0.592926025390625}
{"content": "In brief\nAs of 17 September 2020, the government has cancelled all pre-scheduled inspections of legal entities for consumers rights violations.\nSurprise inspections could increase\nHowever, unscheduled inspections will continue to be conducted and their number is expected to increase, with special rules applying for 2020.\nAccording to the statistics of the Federal Service for the Oversight of Consumer Protection and Welfare (Rospotrebnadzor), more than 85,000 unscheduled inspections were conducted in 2019, each of them uncovering at least two violations of consumers rights. In the majority of cases, the unscheduled inspections were prompted by consumers whose requests had been rejected or left unanswered, who had made test purchases and subsequently filed complaints with the supervisory authority about violations.\nWe expect that the number of surprise inspections could increase, due to heightened activity among consumers and an increase in test purchases. Therefore, we recommend checking your internal systems for handling consumer complaints and meeting the deadlines for responding to them, in order to minimize the risk of creating grounds for a surprise inspection.", "pred_label": "__label__POS", "pred_score_pos": 0.680522084236145}
{"content": "Abstract : Mutations in the TBC1D24 gene were first reported in an Italian family with a unique epileptic phenotype consisting of drug-responsive, early-onset idiopathic myoclonic seizures. Patients presented with isolated bilateral or focal myoclonia, which could evolve to long-lasting attacks without loss of consciousness, with a peculiar reflex component, and were associated with generalized tonic—clonic seizures. This entity was named ''familial infantile myoclonic epilepsy'' (FIME). More recently, TBC1D24 mutations have been shown to cause a variable range of disorders, including epilepsy of various seizure types and severity, non-syndromic deafness, and DOORS syndrome. We report on the electro-clinical features of two brothers, born to first-cousin parents, affected with infantile-onset myoclonic epilepsy. The peculiar epileptic presentation prompted us to perform direct sequencing of the TBC1D24 gene. The patients had very early onset of focal myoclonic fits with variable topography, lasting a few minutes to several hours, without loss of consciousness, which frequently evolved to generalized myoclonus or myoclonic status. Reflex myoclonia were noticed in one patient. Neurological outcome was marked by moderate intellectual disability. Despite the high frequency of seizures, repeated EEG recordings showed normal background rhythm and rare interictal spikes and waves. We found a homozygous missense mutation , c.457G>A/p.Glu153Lys, in the two affected brothers. This observation combined with recent data from the literature, suggest that mutations in TBCD24 cause a pathological continuum, with FIME at the ''benign'' end and severe drug-refractory epileptic encephalopathy on the severe end. Early-onset myoclonic epilepsy with focal and generalized myoclonic seizures is a common characteristic of this continuum.", "pred_label": "__label__POS", "pred_score_pos": 0.5313888788223267}
{"content": "MENUMENU\nA key success factor when implementing a new ERP system is the ability to generate business intelligence.\nJoesoftware can help your organization capture and incorporate valuable data and generate business wins shortly after your Microsoft Dynamics solution is implemented.\nBusiness intelligence (BI) is the acquisition and transformation of raw data into meaningful and useful information.\nBI is not just a simple plug-in to your Dynamics ERP or CRM system. It is the art of understanding your internal and external data sources, connecting data sets and exploiting this information to build valuable insights. BI can empower employees to be more effective decision-makers – analyzing, collaborating and acting on intelligence anytime and anywhere.\nIf mined properly, the data held within your Microsoft Dynamics GP, Business Central, Dynamics 365 CRM or other external systems, can be a valuable resource to your organization. From managing budgets to developing customizable KPI dashboards, Dynamics allows organizations to keep current on changing business conditions.\nJoesoftware can help your organization realize the power of business intelligence through:\nWe’re ready to deliver insights to you and your team. Contact us to discover the power of better business intelligence from your Microsoft Dynamics system.", "pred_label": "__label__POS", "pred_score_pos": 0.923741340637207}
{"content": "Abstract\nBACKGROUND AND PURPOSE: Quantifying MVA rather than MVD provides better correlation with survival in HGG. This is attributed to a specific \"glomeruloid\" vascular pattern, which is better characterized by vessel area than number. Despite its prognostic value, MVA quantification is laborious and clinically impractical. The DSC-MR imaging measure of rCBV offers the advantages of speed and convenience to overcome these limitations; however, clinical use of this technique depends on establishing accurate correlations between rCBV, MVA, and MVD, particularly in the setting of heterogeneous vascular size inherent to human HGG. MATERIALS AND METHODS: We obtained preoperative 3T DSC-MR imaging in patients with HGG before stereotactic surgery. We histologically quantified MVA, MVD, and vascular size heterogeneity from CD34-stained 10-μm sections of stereotactic biopsies, and we coregistered biopsy locations with localized rCBV measurements. We statistically correlated rCBV, MVA, and MVD under conditions of high and low vascular-size heterogeneity and among tumor grades. We correlated all parameters with OS by using Cox regression. RESULTS: We analyzed 38 biopsies from 24 subjects. rCBV correlated strongly with MVA (r = 0.83, P < .0001) but weakly with MVD (r = 0.32, P = .05), due to microvessel size heterogeneity. Among samples with more homogeneous vessel size, rCBV correlation with MVD improved (r = 0.56, P =.01). OS correlated with both rCBV (P = .02) and MVA (P = .01) but not with MVD (P = .17). CONCLUSIONS: rCBV provides a reliable estimation of tumor MVA as a biomarker of glioma outcome. rCBV poorly estimates MVD in the presence of vessel size heterogeneity inherent to human HGG.\nASJC Scopus subject areas Radiology Nuclear Medicine and imaging Clinical Neurology", "pred_label": "__label__POS", "pred_score_pos": 0.8230968713760376}
{"content": "It only takes one slip-and-fall accident to cause significant injuries. Many slip-and-fall accidents are caused by property negligence. Whether you tripped over an uneven surface or you fell down a flight of stairs, it's important to hold property owners accountable. Law Offices of Jeremy W McKey will partner you with a skilled personal injury attorney in Dallas, TX who will help you seek out compensation.\nAttorney Jeremy McKey has more than 15 years of experience practicing law. When you hire him to handle your claim, he will fully investigate the incident, collect any necessary evidence and advocate for you in the courtroom. You aren't alone. Get the legal support you need by working with our personal injury attorney today.\nProperty owners are responsible for the safety of their property, whether it's residential or commercial. If you're injured due to someone else's negligence, you have a right to pursue compensation.\nUnder premises liability law, you may have a case if you...", "pred_label": "__label__POS", "pred_score_pos": 0.6195826530456543}
{"content": "A shared feature of many neural circuits is their organization into synaptic layers. However, the mechanisms that direct neurites to distinct layers remain poorly understood. We identified a central role for Netrins and their receptor Frazzled in mediating layer-specific axon targeting in the Drosophila visual system. Frazzled is expressed and cell autonomously required in R8 photoreceptors for directing their axons to the medulla-neuropil layer M3. Netrin-B is specifically localized in this layer owing to axonal release by lamina neurons L3 and capture by target neuron-associated Frazzled. Ligand expression in L3 is sufficient to rescue R8 axon-targeting defects of Netrin mutants. R8 axons target normally despite replacement of diffusible Netrin-B by membrane-tethered ligands. Finally, Netrin localization is instructive because expression in ectopic layers can retarget R8 axons. We propose that provision of localized chemoattractants by intermediate target neurons represents a highly precise strategy to direct axons to a positionally defined layer.\nCopyright © 2012 Elsevier Inc. All rights reserved.", "pred_label": "__label__POS", "pred_score_pos": 0.84628826379776}
{"content": "During the 1990s, The Bridge’s open employment program expanded and went from strength to strength. In 1995, after being nominated by The Bridge, partner organisation Kenman Kandy won the Prime Minister’s Employer of the Year Award.\n‘To all parents, I wanted to say, if your son or daughter gets a chance to try and go for work, let them try. Their life will be changed, like it did for my son. I hope that is enough for you to understand how proud I feel about Giuseppe.’\nMaria Di Benedetto, Parent, 1990s promotion video\nIt was a pioneering time for the sector. The widespread emphasis on deinstitutionalisation through the 1980s and into the 1990s, led to the creation of new service models with a focus on person-centred practice. In this period The Bridge’s services were also extended to participants with more complex needs. The 1996 merger with Westernport Adult Service Providers meant an expansion of reach and service provision.", "pred_label": "__label__POS", "pred_score_pos": 0.7268750071525574}
{"content": "I have been called an old soul, which is why I love mosaic. Mosaic bridges the ancient and modern worlds, in all its elements: inspiration, design, materials. Mosaic is design, and it is work. Mosaic is spiritual, yet absolutely physical. Mosaic blends soft beauty and hard-edged tesserae. Mosaic births something new out of brokenness.\nLately, I’ve been experimenting more with sewing. My mom is a fine seamstress, but I only recently really started getting into this. In the summer of 2018, I made my first quilt, a king-sized creation fully designed, pieced, and quilted by me–on a small domestic machine. I don’t let a big project deter me; I had a vision, I learned what I needed to learn, and I love that quilt!\nIn bringing any creative work from dream to concrete reality, I thrive on the interplay of problem-solving brain, working with one’s hands, and honoring the unique tools of the trade. I sense the legacy of my family — a quiltmaker, a steelworker, farmers – people who worked with tools to create durable, useful, and beautiful items for their communities.\nMy artist’s mindset informs who I am as an educator and leader, too:\nI see the big picture AND the details that are required to make the vision a reality. I backwards plan with the end in mind, and adapt and adjust when something goes wrong. I don’t let mistakes stop me; they often lead to new discoveries. I want to make beautiful, practical things for people–not fragile, breakable things that one can never touch.", "pred_label": "__label__POS", "pred_score_pos": 0.6212403774261475}
{"content": "Support our nonpartisan, nonprofit research and insights which help leaders address societal challenges.Donate\nEXECUTIVE SUMMARY\nImpact of COVID-19 Crisis on the Chinese Economy– Stronger than expected momentum in May suggests that Q2 growth will likely be positive. However, aggregate growth will not likely resurge to a pre-coronavirus level until Q4. Risk remains biased toward the downside due to global trade and domestic labor market weakness.\nInvestment Trends– Fixed Asset Investment returned to positive growth y-o-y in May. Strong fiscal expansion boosted infrastructure investment, and the loosening credit environment has fueled investment recovery in real estate development. Growth remains weak in manufacturing investment. But, if the industrial output prices’ uptick seen in June continues, and corporate profit growth strengthens as a result, then growth in manufacturing investment may improve in the 2H.\nTo get complimentary access to this publication click \"Read more\" to sign in or create an account.", "pred_label": "__label__POS", "pred_score_pos": 0.7282316088676453}
{"content": "News Eck report: agreement on mercury regulation ‘too vague’\nThe Council and the European Parliament have reached an agreement on an EU regulation on mercury – one of the ten top pollutants in the world according to the World Health Organisation (WHO). Prior to its entry into force, the agreement has to be confirmed and formally approved by EU member states and by the plenary.\nAfter a marathon final round of negotiations that lasted into the early hours of Wednesday, the two parties agreed on the conditions for the use of mercury in Europe, under the scope of the International Minamata Convention which is aimed at significantly reducing emissions and releases of mercury into the environment.\nGUE/NGL MEP\nStefan Eck, the rapporteur for the file, acknowledged “some progress” on a few of the topics addressed in the final text comparing it with the original draft proposed by the European Commission. However, he considered “this political agreement too weak, too vague”. He also added that “it falls well short of his personal expectations when it comes to the protection of human health and the environment”.\nThe German rapporteur was particularly critical of a “broad coalition of shadow rapporteurs from the other political groups for committing too early to the feeble proposals by the Slovak EU presidency”. He also accused member states “of duplicity and collusion with big economic interests and operators for opposing the more progressive and environmentally ambitious proposal from the Parliament's Committee on the Environment and Public Health (ENVI).”\n“I found myself outnumbered by my colleagues who once supported me but then broke rank amongst the Parliament's negotiators. They finally forced me to leave aside some of the best and most ambitious ENVI proposals to dramatically reduce the quantities of mercury present in our ecosystems including a phased ban on dental amalgam,” Eck concluded.", "pred_label": "__label__POS", "pred_score_pos": 0.5756385326385498}
{"content": "Caterpillar has reported sales for its construction segment of US$5.28 billion in the third quarter of 2019, a decline of 7% compared to sales in the same quarter in 2018.\nThis decline of approximately US$394 million was attributed by Caterpillar to lower sales volumes driven by the unfavourable impact from changes in dealer inventories.\nDespite this fall in sales, there were some regions around the world which saw an increase in sales from the third quarter of 2018 to the third quarter of 2019. North America saw an increase of 3% and Latin America 12%, although this is not surprising given the low level of sales for this region previously.\nEurope, Africa and the Middle East (EAME) saw a decline in sales of 6% and the Asia Pacific region saw a drop of 29%. The fall in sales in the Asia Pacific region was said to be mainly due to lower demand in China, including unfavourable changes in dealer inventories amid continued competitive pressures.\nConstruction Industries’ profit was US$940 million in the third quarter of 2019, a decrease of US$118 million, or 11%, compared with US$1.058 billion in the third quarter of 2018.\nThe mining and quarrying segment (resource industries) also saw a decline in sales from the third quarter of 2018 to 2019, with this segment seeing sales fall 12%. Caterpillar attributed this to dealers decreasing inventories and general economic uncertainty.\nAll regions saw a decline in sales, with North America down 7%, Latin America 18%, EAME 31% and Asia Pacific 6%.", "pred_label": "__label__POS", "pred_score_pos": 0.7759671211242676}
{"content": "An Energy Performance Certificate (EPC) provides a rating from A (most efficient) to G (least efficient) and is valid for ten years before needing renewal. All landlords are required to purchase an EPC, and it must be of an E rating or higher. Renting without an EPC or with one which fails to meet the requirements is a criminal offence and can result in penalties and fines.", "pred_label": "__label__POS", "pred_score_pos": 0.8363770246505737}
{"content": "Targeting EV’s With Production Of High-Grade Nickel Concentrate\nGiga Metals Corp. (TSXV: GIGA) has revealed the results of a preliminary economic assessment (PEA) for the Turnagain Nickel-Cobalt Project in British Columbia, Canada.\nThe PEA is an update of the 2011 PEA confirming the ability of Turnagain to produce high-quality nickel concentrate, such as that needed to make pure nickel products for the electric vehicle (EV) market, in a socially and environmentally responsible manner.\nGiga Metals’ primary driver for this update was to deliver a reliable and comprehensive PEA incorporating all project-related components for use for discussion with strategic investors, for targeting improvement opportunities, and to serve as a base for future engineering studies.\nThe PEA indicates a long-life, large-scale project. With a projected build capital of US$1.4 billion (Phase 1) and US$0.5 billion (Phase 2) including significant investment for a powerline delivering low-cost, clean, low-carbon power from BC Hydro (mainly hydroelectric), the projected capital intensity is US$51,500 per annual tonne nickel at full rates (years six to 20).\nAt full rate (years six to 20), the project is expected to deliver 37,149 tonnes per year of nickel in a high-grade nickel concentrate at an operating cost of US$3.20/lb nickel before by-product credits at the plant gate (all production data are metal in produced concentrate), or US$3.04/lb nickel after credits and shipping (in concentrate, delivered CIF Asia port).\nAt metals prices of U.S. $7.50 per pound of nickel and smelter terms of 78% NSR as provided by analysts Wood Mackenzie, Turnagain is expected to have a pre-tax IRR of 6.3%. At the environmental, social, and governance (ESG)-premium pricing case, the project is expected to have a pre-tax IRR of 9.4%. The base case pricing is based on a relatively conservative EV demand forecast creating a nickel shortfall after 2030 growing to 1.3 Mt/y by 2040. This projected deficit requires more than 35 Turnagain-scale projects to fill. Based on the resources previously disclosed including 1.07 billion tonnes of Measured and Indicated and 1.1 billion tonnes of Inferred (respectively, 5.2 billion pounds and 5.5 billion pounds of nickel content), the project is expected to operate for at least 35 years, producing 1.2 million tonnes of nickel-in-concentrate at an average grade of 18% nickel and 1% cobalt, comparable to the best nickel concentrates currently produced in the world.", "pred_label": "__label__POS", "pred_score_pos": 0.5899227857589722}
{"content": "The world's leading climate scientists now state that there is scientific support for declaring a\nstate of planetary emergency. We propose that a planetary crisis represents a global spiritual emergency, and is a catalyst for a global awakening of collective human consciousness.\nWe propose that\nemergency mode offers an empowering psychological state for individuals to navigate experiences of crisis. Rather than a state that exacerbates negative emotions such as fear, anxiety, panic, or paranoia, it is a state that can facilitate enhanced awareness and collective transformative action.\nWe propose that the climate emergency represents a\nrite of passage for humanity, creating a situation that requires global cooperation. We believe that a peaceful revolution is necessary to facilitate the evolution of our species. We also believe this global crisis parallels rites of passage described within Indigenous cultures, and that their wisdom is vital to help guide our actions.\nIn this petition, we address the United Nations, and declare that humanity is facing a\nstate of planetary emergency, which requires a GLOBAL CONSCIOUSNESS (R)EVOLUTION, undertaken in emergency mode, and guided by Indigenous and other wisdom traditions.\nOnce this petition reaches 100,000 signatures, it will be sent to the UN as a message from concerned citizens to declare a state of planetary emergency.\nThank you.", "pred_label": "__label__POS", "pred_score_pos": 0.9994190335273743}
{"content": "Quetiapine generic fumarate extended-release tablets (canadian Seroquel XR, AstraZeneca) are now available as a once-daily medication for schizophrenia in adults. With this formulation, patients can achieve a dose within the recommended range as early as the second day of treatment.\nThe FDA’s approval was based on a clinical trial of Seroquel XR at doses of 400, 600, and 800 mg/day.\nThe previously recommended initial dose was 25 mg twice daily with increments of 25 to 50 mg twice or three times daily on the second and third days, as tolerated, to a target dose range of 300 to 400 mg daily by the fourth day, given twice or three times per day.\nThe product includes two boxed warnings: one concerns elderly patients with dementia-related psychoses, and the other mentions a risk of suicidality in children and adolescents.", "pred_label": "__label__POS", "pred_score_pos": 0.9987089037895203}
{"content": "PhishFarm: A Scalable Framework for Measuring the Effectiveness of Evasion Techniques Against Browser Phishing Blacklists\nAbstract—Phishing attacks have reached record volumes in recent years. Simultaneously, modern phishing websites are grow- ing in sophistication by employing diverse cloaking techniques to avoid detection by security infrastructure. In this paper, we present PhishFarm: a scalable framework for methodically testing the resilience of anti-phishing entities and browser blacklists to attackers’ evasion efforts. We use PhishFarm to deploy 2,380 live phishing sites (on new, unique, and previously-unseen .com domains) each using one of six different HTTP request filters based on real phishing kits. We reported subsets of these sites to 10 distinct anti-phishing entities and measured both the occurrence and timeliness of native blacklisting in major web browsers to gauge the effectiveness of protection ultimately extended to victim users and organizations. Our experiments revealed shortcomings in current infrastructure, which allows some phishing sites to go unnoticed by the security community while remaining accessible to victims. We found that simple cloaking techniques representative of real-world attacks— in- cluding those based on geolocation, device type, or JavaScript— were effective in reducing the likelihood of blacklisting by over 55% on average. We also discovered that blacklisting did not function as intended in popular mobile browsers (Chrome, Safari, and Firefox), which left users of these browsers particularly vulnerable to phishing attacks. Following disclosure of our findings, anti-phishing entities are now better able to detect and mitigate several cloaking techniques (including those that target mobile users), and blacklisting has also become more consistent between desktop and mobile platforms— but work remains to be done by anti-phishing entities to ensure users are adequately protected. Our PhishFarm framework is designed for continuous monitoring of the ecosystem and can be extended to test future state-of-the-art evasion techniques used by malicious websites.", "pred_label": "__label__POS", "pred_score_pos": 0.6016403436660767}
{"content": "With the growing popularity of hemp-derived cannabidiol (hemp CBD) products in e-commerce, the U.S. Patent and Trademark Office (USPTO) has seen a significant influx of trademark applications used in association with CBD goods. However, many of these applications have been denied by the USPTO. This article briefly addresses the reasons for these denials and discusses the trademark protections currently available to the industry.\nTo secure federal trademark registration, a mark’s use in commerce must be lawful under federal law.\nAlthough the Agricultural Improvement Act of 2018 (the 2018 Farm Bill) legalized the production of hemp and hemp derivatives, including hemp CBD, by removing hemp from the Controlled Substances Act’s definition of marijuana, the new law did not legalize the production of hemp CBD products. Instead, the 2018 Farm Bill expressly preserved the FDA’s authority to regulate these products under the Food, Drug and Cosmetic Act (FDCA).\nAs I have discussed in this column (here and here), the FDA takes the firm position that it is unlawful to sell and market in commerce CBD food and dietary supplements, pursuant to the FDCA and the Drug Exclusion Rule. Specifically, the FDA argues that because CBD was approved and investigated as a drug ingredient before it was sold and marketed as a food or a dietary supplement, these products may not be lawfully introduced in commerce. Consequently, the USPTO, which defers to the FDA’s position, opines that “registration of marks for foods, beverages, dietary supplements, or pet treats containing CBD will still be refused as unlawful under the FDCA, even if derived from hemp.”\nCosmetics containing hemp CBD, however, are in a more ambiguous space, as the FDA has indicated that the sale and marketing of these products may be permissible. In guidance released on its website, the FDA provides that this category of product is lawful so long as they are not adulterated, mislabeled, or intended to affect the structure or function of the body, or to diagnose, cure, mitigate, treat, or prevent disease (\ni.e., intended as a drug).\nTherefore, when applying for federal trademark protection, hemp CBD companies must be very clear about the type of cosmetic product they are selling and wanting to protect. For instance, while a hemp CBD cosmetic product in Class 003 (soaps, perfumery, essential oils, cosmetics, hair lotions, and dentifrices) may be acceptable and eligible for protection, a hemp CBD salve intended to relieve muscle soreness in Class 005 (pharmaceuticals and other preparations for medical or veterinary purposes) won’t likely qualify.", "pred_label": "__label__POS", "pred_score_pos": 0.8293537497520447}
{"content": "Women's economic inequality and domestic violence: exploring the links and empowering women\nEconomic empowerment of poor households is a key entry point for development organisations concerned with economic inequality. Over the decades, gender inequality has emerged as a key concern, and the result has been women’s economic empowerment (WEE) programming. This article is a study of the impact of WEE programming on domestic violence (DV) against women. While this link has received some attention in gender and development literature, evaluations and impact assessments in development organisations have not consistently focused on the possibility of increased or decreased DV as a result of the challenge WEE represents to gender power relations. Drawing on the experience of Oxfam and other development organisations, we offer recommendations for practitioners aimed at better programme integration and more holistic empowerment. Aiming to challenge economic inequality between households involves better understanding of the impact of WEE programming on intra-household gender inequality, including rates of DV. This requires planning to anticipate these possible impacts and ensure women are able to gain from programming without placing themselves at risk. This article is hosted by our co-publisher Taylor & Francis. For the full table of contents for this and previous issues of this journal, please visit the Gender and Development website.", "pred_label": "__label__POS", "pred_score_pos": 0.8462121486663818}
{"content": "The influence of program format on the professional development of science teachers: Teacher perceptions of ap and honors science courses\nExamined which of the formats for advanced science instruction, Advanced Placement (AP) or honors (HS), was more effective at fostering communication between educators and stimulating their professional development. Interviews were conducted with 155 teachers with experience teaching both HS and AP. Ss believed AP was more effective in encouraging and facilitating professional communication and development. Teaching AP classes facilitated or necessitated more contacts with other professionals and stimulated more professional interaction. Ss learned significantly more as a result of teaching AP classes.", "pred_label": "__label__POS", "pred_score_pos": 0.8613694906234741}
{"content": "Most of the food included as a component of a weight-loss diet have a couple of things in common: they’re high in fiber and have a low energy density—implying that you can eat an average estimated portion without trying too hard on calories.\nResearch by a scientist has uncovered that a few foods may affect craving. These could be helpful for weight reduction when fused into a healthful diet and lifestyle.\nOne examination found that a few foods — including fruits, vegetables, nuts, whole grains, and yogurt — were associated with weight loss.\nIn a similar report, potato chips, sugary drinks, red meats, and processed meats were related to weight gain.\nIn light of these findings, it might be ideal to avoid fried foods, foods with added sugar, high-fat meats, and processed foods when trying to move the pounds.\nAvocados:\nAvocados are wealthy in monounsaturated fatty acids, dietary fiber, potassium, and phytochemicals. Individuals who eat avocados will, in general, have lower BMI, body weight and waist circumference than individuals who avoid this green superfood, per an examination in\nNutrition Journal.\nWhile avocados are higher in calories than different fruits grown from the ground, their wonderful fat and fiber combo may enable you to slim down. In addition to this, add some to your serving of mixed greens, sandwich or taco night for a burst of creaminess and flavor.\nEggs:\nEggs are a prominent food, especially for morning meals, that may help prompt weight loss.\nIn a study of 21 men, scientists thought about the impacts of eating eggs or having a bagel for breakfast on food intake, appetite, and fulfillment.\nThey found that men who had the egg breakfast ate fundamentally less at their next supper, and in the accompanying 24 hours, than the individuals who had the bagel breakfast.\nHowever, the individuals who had eaten the eggs additionally reported less hungry and more fulfilled 3 hours after breakfast than the individuals who had eaten the bagel.\nCereal:\nBeginning the day with a bowl of cereal could likewise result in a lower number on the scales.\nAn examination including 47 adults took a gander at contrasts in hunger, fullness, and next meal intake after members ate oats, rather than oat-based ready-to-eat breakfast cereal.\nSubsequent to eating oats, members felt fundamentally more full and less eager than after eating the oat. Additionally, their calorie consumption at lunch was lower in the wake of eating oats than subsequent to having breakfast cereal.\nWhile the two-morning meals contained a similar amount of calories, the oats gave more protein, more fiber, and less sugar than the cereal.\nYogurt:\nYogurt is protein-packed and loaded with\nprobiotics, which are useful for gut health and may help your weight loss efforts.\nMoreover, your gut health can affect your weight. So, eating more fiber and probiotics helps keep your gut microorganisms upbeat, which can be useful for your digestion. However, the utilization of Greek yogurt was related to decreased craving and expanded satiety. Simply watch out for added sugars in flavored yogurts, which just include calories. Rather, utilize fresh fruits to sweeten plain yogurt.\nAlmonds:\nAlmonds are a superb source of fiber, and they’re high in protein. Eating foods with the one-two punch of fiber and protein can enable you to feel fuller—which makes it less enticing to go after an undesirable nibble between meals.\nWealthy in\nvitamin E and a decent source of heart-healthy mono-and polyunsaturated fats, almonds are an extraordinary choice to sprinkle over a serving of salad or side dish. Moreover, you can utilize them in pesto instead of walnuts or pine nuts, top your morning granola with them, or simply keep a little sack in your purse as an emergency snack.", "pred_label": "__label__POS", "pred_score_pos": 0.8596764206886292}
{"content": "Regardless of the time of the year, you take a risk every time you get behind the wheel. Even if you're a good driver, things can happen around you that lead to an accident.\nThe fall season in Colorado is particularly dangerous, as there are a variety of unique hazards that could challenge you. Here are five to protect against.\nRain:As summer turns to fall, there's a good chance that more rain will move into the area. Not only does it impact visibility, but it also makes the roadways slick. Back to school traffic:You should expect more vehicles, including cars and school buses, to be on the road during the fall season. Additionally, you must contend with children who don't always walk on the sidewalk. Fog:Cooler fall mornings often result in a dense layer of fog. If you've driven in foggy conditions in the past, you know just how challenging it can be. Decreased visibility should lead you to use your headlights (not your high beams), slow down and leave more space between your vehicle and others. Wildlife:For example, deer activity is more common during the fall months. These animals, among others, dart into the roadway without warning. Even if you're moving at a slow rate of speed, a deer can surprise you. Sun glare:Hotter summer days may be in the past, but that doesn't mean the sun is gone for good. Sun glare is particularly troublesome during the fall months, as it often reflects off of wet roads.\nExperience and knowledge can help you stay safe when driving during the fall months, but it does nothing to protect you against other drivers.\nFor example, you may understand the importance of slowing down in inclement weather, but other drivers ignore the conditions altogether.\nIf you're injured in a motor vehicle accident, don't rush to get out of your vehicle. First, check yourself for injuries and then call 911. If you're in a safe place and able to do so, take photos of the accident scene and exchange information with the other driver.\nOnce you receive medical treatment, it's then time to file an insurance claim and seek other ways to hold the negligent driver responsible for your injuries.", "pred_label": "__label__POS", "pred_score_pos": 0.7838728427886963}
{"content": "Enzymedica Digest Gold™ with ATPro™\nEnzyme deficiencies may result from a combination of age, diet and lifestyle. These deficiencies can lead to a variety of digestive discomforts, including occasional gas, bloating indigestion and irregularity.\nDigest Gold is an advanced formula that breaks down carbohydrates, fats, fiber ad protein. The enzymes in Digest Gold support optimal digestion by helping the body absorb nutrients and convert food into energy. Digestive well-being improves concentration and increases vitality. Digest Gold is an excellent choice for individuals seeding a high-potency enzyme formula.\n*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.", "pred_label": "__label__POS", "pred_score_pos": 0.9001942873001099}
{"content": "The oxygen-sensing prolyl hydroxylase domain (PHD) enzymes are key to maintaining tissue homeostasis during hypoxia via their regulation of the expression and activity of HIF, the master transcription factor for the hypoxic response. In this issue of the JCI, Yamamoto, Hester, and colleagues show that temporal and reversible inhibition of PHD2 in vivo leads to systemic autoimmune disorder. The work demonstrates that a reduction of PHD2 leads to impairment of immunosuppressive Treg function via a HIF2α-dependent mechanism, without altering Foxp3 expression. This study indicates that a PHD2/HIF2α axis is critical for maintaining proper Treg function.\nWeiping Zou, Yatrik M. Shah", "pred_label": "__label__POS", "pred_score_pos": 0.9928224682807922}
{"content": "Abstract\nHomologue synapsis is required for meiotic chromosome segregation, but how synapsis is initiated between chromosomes is poorly understood. In Caenorhabditis elegans, synapsis and a checkpoint that monitors synapsis depend on pairing centers (PCs), cis-acting loci that interact with nuclear envelope proteins, such as SUN-1, to access cytoplasmic microtubules. Here, we report that spindle assembly checkpoint (SAC) components MAD-1, MAD-2, and BUB-3 are required to negatively regulate synapsis and promote the synapsis checkpoint response. Both of these roles are independent of a conserved component of the anaphase-promoting complex, indicating a unique role for these proteins in meiotic prophase. MAD-1 and MAD-2 localize to the periphery of meiotic nuclei and interact with SUN-1, suggesting a role at PCs. Consistent with this idea, MAD-1 and BUB-3 require full PC function to inhibit synapsis. We propose that SAC proteins monitor the stability of pairing, or tension, between homologues to regulate synapsis and elicit a checkpoint response.\nReferences Synaptonemal Complex Components Are Required for Meiotic Checkpoint Function in Caenorhabditis elegans Differential requirement for Bub1 and Bub3 in regulation of meiotic versus mitotic chromosome segregation Citations Meiotic recombination in C. elegans initiates by a conserved mechanism and is dispensable for homologous chromosome synapsis Checkpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2 Synapsis-dependent and -independent mechanisms stabilize homolog pairing during meiotic prophase in C. elegans Centrosome maturation and mitotic spindle assembly in C. elegans require SPD-5, a protein with multiple coiled-coil domains The Cdc20 homolog, FZY-1, and its interacting protein, IFY-1, are required for proper chromosome segregation in Caenorhabditis elegans Components of the spindle assembly checkpoint regulate the anaphase-promoting complex during meiosis in Caenorhabditis elegans A family of zinc-finger proteins is required for chromosome-specific pairing and synapsis during meiosis in C. elegans Differential timing of S phases, X chromosome replication, and meiotic prophase in the C. elegans germ line Systematic analysis in Caenorhabditis elegans reveals that the spindle checkpoint is composed of two largely independent branches Meiotic chromosome homology search involves modifications of the nuclear envelope protein Matefin/SUN-1 Polo kinases establish links between meiotic chromosomes and cytoskeletal forces essential for homolog pairing Synaptonemal complex-dependent centromeric clustering and the initiation of synapsis in Drosophila oocytes Dissection of the NUP107 nuclear pore subcomplex reveals a novel interaction with spindle assembly checkpoint protein MAD1 in Caenorhabditis elegans Matefin/SUN-1 phosphorylation is part of a surveillance mechanism to coordinate chromosome synapsis and recombination with meiotic progression and chromosome movement Chromosome movements promoted by the mitochondrial protein SPD-3 are required for homology search during Caenorhabditis elegans meiosis Syndecan-2 is upregulated in colorectal cancer cells through interactions with extracellular matrix produced by stromal fibroblasts Related Concepts Related Feeds Cell Checkpoints & Regulators\nCell cycle checkpoints are a series of complex checkpoint mechanisms that detect DNA abnormalities and ensure that DNA replication and repair are complete before cell division. They are primarily regulated by cyclins, cyclin-dependent kinases, and the anaphase-promoting complex/cyclosome. Here is the latest research.", "pred_label": "__label__POS", "pred_score_pos": 0.5785046815872192}
{"content": "Abstract\nThe M2 protein of influenza A viruses forms a tetrameric proton channel that is targeted by the amantadine class of antiviral drugs. A S31N mutation in the transmembrane (TM) domain of the protein has caused widespread amantadine resistance in most of the currently circulating flu viruses. Recently, a new family of compounds based on amantadine- and aryl-substituted isoxazole were discovered to inhibit the S31N channel activity and reduce replication of S31N-harboring viruses. We now use solid-state NMR spectroscopy to investigate the effects of one of these isoxazole compounds, WJ352, on the conformation of the S31N TM segment and the dynamics of the proton-selective residue, His37. Chemical shift perturbations show that WJ352 changes the conformational equilibrium of multiple TM residues, with the maximal perturbation occurring at the crucial Asn31.\n13C- 2H distance measurements and 1H- 1H NOE cross peaks indicate that the adamantane moiety of the drug is bound in the spacious pore between Asn31 and Gly34 while the phenyl tail is located near Val27. Thus, the polar amine points to the channel exterior rather than to His37, in contrast to amantadine and rimantadine in the wild-type channel, suggesting that the drug is significantly stabilized by hydrophobic interactions between the adamantane and the TM peptide. 15N and 13C chemical shifts indicate that at low pH, His37 undergoes fast exchange among the τ tautomer, the π tautomer, and the cationic state due to proton transfer with water. The exchange rate is higher than the wild-type channel, consistent with the larger single-channel conductance of the mutant. Drug binding at acidic pH largely suppresses this exchange, reverting the histidines to a similar charge distribution as that of the high-pH closed state. ASJC Scopus subject areas Catalysis Chemistry(all) Biochemistry Colloid and Surface Chemistry", "pred_label": "__label__POS", "pred_score_pos": 0.7683242559432983}
{"content": "Abstract\nBackground: Osteochondral allograft transplantation is technically demanding. It is not always possible to place the surface of the graft perfectly flush with the surrounding cartilage. One must often choose between placing at least some portion of the surface of the graft slightly elevated or recessed. The effect of this choice on joint contact pressure is unknown.Purpose: This study was undertaken to determine the effect of graft height mismatch on joint contact pressure in the ankle.Study Design: Controlled laboratory study.Methods: Ten human cadaveric ankles underwent osteochondral grafting by removal then replacement of an osteochondral plug. Six conditions were tested: intact, graft flush, graft elevated 1.0 mm, graft elevated 0.5 mm, graft recessed 0.5 mm, and graft recessed 1.0 mm. Joint contact pressures were measured with a Tekscan sensor while loads of 200 N, 400 N, 600 N, and 800 N were sequentially applied.Results: The peak contact pressure at the graft site for the flush condition was not significantly different from the intact condition for either medial or lateral lesions. In contrast, peak pressure on the opposite facet of the talar dome was significantly increased during the flush condition for the medial but not the lateral grafts. Elevated grafts experienced significantly increased contact pressures, whereas recessed grafts experienced significantly decreased pressures. These changes were greater for lateral than for medial lesions. Reciprocal changes in joint contact pressures were found on the opposite facet of the talus with elevated grafts on the lateral side and recessed grafts on the medial side.Conclusion: Flush graft placement can restore near-normal joint contact pressure. Elevated graft placement leads to significant increases in joint contact pressure at the graft site. Recessed graft placement leads to a transfer of pressure from the graft site to the opposite facet of the talus.Clinical Relevance: Osteochondral grafts in the talus should be placed flush if possible or else slightly recessed.\nKeywords graft height mismatch joint contact pressure osteochondral graft talus ASJC Scopus subject areas Orthopedics and Sports Medicine Physical Therapy, Sports Therapy and Rehabilitation", "pred_label": "__label__POS", "pred_score_pos": 0.5639022588729858}
{"content": "I’m studying for my Computer Science class and need an explanation.\nIn a traditional IT environment, after a cyber-attack, the incident response team is responsible for conducting investigation and gathering evidence. In a cloud computing environment, incident investigation responsibility is split between the company and the cloud service provider. There is a skill gap in the digital forensics expertise to help gather relevant information. Therefore, for smaller businesses or even larger corporations, Forensic-as-a-Service could be used to fill the much needed skill gap. Forensic-as-a-Service is an end-to-end incident investigation service that is aimed to help collect evidence specifically for legal purposes.\nSearch the Internet and select a Forensic-as-a-Service provider for your discussion.", "pred_label": "__label__POS", "pred_score_pos": 0.9769977331161499}
{"content": "The Mexican LED lighting market is expected to witness a CAGR of 17.1% during the forecast period (2020-2025). In the current market state, LEDs have gained a mainstream in the lightings market. Key factors behind this are the continuous declining LED prices in the country coupled with favorable government initiatives.\nThe National Public Lighting Program to replace traditional lightings with LED aimed at sustainable use of energy.The National Public Lighting Program in support from CONUEE, and the Federal Electricity Commission for guidance on implementation, verification, and financing of efficient lighting projects.\nAccording to the World Bank, Over 2.6 million high-efficient light bulbs were sold to the residential customers for a subsidized cost of 60% in two cities (Guadalajara and Monterrey) as part of the pilot project demonstration for efficient LED lighting. This project - ILUMEX has surpassed its physical targets and successfully demonstrated the feasibility of reducing both greenhouse gas emission and reduction in electricity consumption.\nNevertheless, due to the availability of low-cost materials and a recovering economy, global players are setting up their manufacturing facilities in the region. For instance, in June 2019, a USD 1 billion plant in the State of San Luis Potosi, Mexico, was unveiled, which will be BMW's second in the Americas when production starts in early 2021.\nHowever, the market has been affected by the recent outbreak of COVID 19, and companies have been forced to restructure their strategies to deal with the ongoing pandemic. Companies, like Signify, were the worst hit due to this pandemic. Signify in February 2020 had planned to upgrade their solar connected street light to toggle between solar and grid power by using Philips Combo Charge Controller. But the company has gone into financial crunch due to the COVID outbreak, the company in March 2020 had announced a 20 percent pay cut of all their employees.\nKey Market Trends\nIncreasing Demand for Outdoor Lighting Due to Smart Development Initiatives to Drive the Market Growth\nIn Mexico, even though the LED penetration is low for the residential end user, the government is mainly focusing on outdoor lighting for reducing electricity consumption as well as greenhouse gas emission. According to the study by INEGI, the average penetration of LED in residential rooms is just 12% in the country.\nRecently, the government has initiated the project to replace all the streetlights in the Guadalajara city, half of the total 80,000 streetlights in the city across 200 districts along 100 roads. The project is reportedly self-financed with the energy savings it creates. The program is planned on a 10-year leasing contract valued at MXN 300 million (close to USD 19 million). With this program, the city is expected to create savings of over USD 500,000 per month.\nThe Servicio Express Aeropuerto Carret on Monterrey-Laredo Highway needed an energy-efficient lighting solution for the service station's parking lot and canopy that covers the pumping stations. The authority has mentioned that by replacing the old 23 inefficient metal halide flood and canopy fixtures with LED enabled to save energy of 268,000 kWh and USD 32,160 in energy and maintenance.\nIndustrial Use of LED Lighting in Mexico is Expected to Grow Significantly\nWith around 621 medical device manufacturing companies, Mexico is one of the largest exporters of medical devices to the United States, and parts of Latin America, known for its high quality. With export revenues going as high as USD 9 billion, in 2019, medical device manufacturers are having zero tariffs on imports and exports under NAFTA. This makes Mexico a potential destination for setting up a UV-based medical device franchise, which is one of the highest growing fields of UV-LED light applications.\nMexico has a severe freshwater shortage, and the re-use of water is extensively practiced across the region. Considering this, UV-based consumer products, like sterilizers and disinfectants, are expected to gain importance over the forecast period considering that 80% are urban population, according to the World Bank. Additionally, the WHO has stated that the use of UV-based disinfectants is becoming prevalent in the country; hence, healthcare-associated infections (HAIs) are the most common reasons for death.\nVendors offering LED solutions are expanding their presence in Mexico to support ongoing local demand. For instance, Aquionics, a part of the Halma Group, and a prominent UV-LED based disinfectant product manufacturer, has strengthened its team in Mexico, anticipating the demand for industrial LED lighting.\nCompetitive Landscape\nThe Mexican LED lighting market is highly fragmented, with the presence of a large number of domestic as well as international players in the country. Due to the fragmented nature of the market, the competition among the players is high.\nMarch 2020 - Signify announced the completion of the acquisition of Cooper Lighting Solutions from Eaton for USD 1.5 billion. With this acquisition, the company has planned to focus on the innovation of connected lightings and systems. This is estimated to drive the revenue growth of the company in the North American market with an aimed increase in professional revenues from 42% to 53%.\nFebruary 2020 - Signify introduced a new integrated Philips Combo Charge Controller for streetlights, enabling the emergence of a hybrid solar system. With this innovation, the company is aiming at creating a new market for solar powered outdoor lightings in Asia, Africa, South America, Australia, and Spain, where the company has already installed solar-powered lights.\nReasons to Purchase this report:\nThe market estimate (ME) sheet in Excel format\n3 months of analyst support", "pred_label": "__label__POS", "pred_score_pos": 0.9885810613632202}
{"content": "Abstract\nThe NAD-dependent histone deacetylase sirtuin (Sirt)1 is implicated in a wide variety of physiological processes, ranging from tumorigenesis to mitochondrial biogenesis to neuronal development. Recent studies indicate that Sirt1 is a critical regulator of both the innate and adaptive immune response in mice and its altered functions are likely involved in autoimmune diseases. Small molecules that modulate Sirt1 functions are potential therapeutic reagents for autoimmune inflammatory diseases. In this review, we highlight the functions of Sirt1 in the immune system focusing on the underlying molecular mechanisms, and the potential of Sirt1 as a therapeutic target for autoimmune diseases.\nKeywords T-cell activation autoimmunity sirt1 tolerance ASJC Scopus subject areas Immunology Cell Biology", "pred_label": "__label__POS", "pred_score_pos": 0.8632467985153198}
{"content": "Abstract\nObjective: Studies on the effects of digoxin in patients with right ventricular failure and normal left ventricular function have not been performed. We evaluated the short-term effects of digoxin administration in patients with primary pulmonary hypertension on hemodynamics, neurohormones, and baroreceptor responsiveness. Design: This was a prospective study with patients serving as their own controls. Setting: University Hospital Intensive Care Unit with central monitoring. Patients: Seventeen patients with primary pulmonary hypertension and symptomatic heart failure were enrolled. Interventions: Following baseline hemodynamics, neurohormonal samples were drawn and the heart rate response to change in blood pressure following a challenge of phenylephrine and nitroprusside were recorded. One mg of intravenous digoxin was given and the measurements repeated after 2 hours. Results: Following digoxin there was a significant increase in cardiac output (3.49±1.2 to 3.81±1.2 L/min., p=0.028), a significant fall in norepinephrine (680±89 to 580±85 pg/ml, p=.013), and a significant increase in atrial natriuretic peptide (311±44 to 421±9 pg/ml, p=0.01). All of the patients had changes in heart rate and blood pressure following phenylephrine and nitroprusside challenge, but there was no significant difference in the change in heart rate response to change in blood pressure when rechallenged after digoxin treatment. Conclusion: Digoxin produces a modest increase in cardiac output in patients with pulmonary hypertension and fight ventricular failure, as well as a significant reduction in circulating norepinephrine. No detectable effects of digoxin on baroreceptor responsiveness were apparent. The use of digoxin in pulmonary hypertension is warranted.\nKeywords Digoxin Heart failure Pulmonary heart disease ASJC Scopus subject areas Pulmonary and Respiratory Medicine Critical Care and Intensive Care Medicine Cardiology and Cardiovascular Medicine", "pred_label": "__label__POS", "pred_score_pos": 0.808961033821106}
{"content": "In this study, a different method was applied for boron removal by using vermiculite as the adsorbent. Vermiculite, which was used in the experiments, was not modified with adsorption agents before boron adsorption using a separate process. Hexadecyltrimethylammonium bromide (HDTMA) and Gallic acid (GA) were used as adsorption agents for vermiculite by maintaining the solid/liquid ratio at 12.5 g/L. HDTMA/GA concentration, contact time, pH, initial boron concentration, inert electrolyte and temperature effects on boron adsorption were analyzed. A three-factor, three-level Box-Behnken design model combined with response surface method (RSM) was employed to examine and optimize process variables for boron adsorption from aqueous solution by vermiculite using HDTMA and GA. Solution pH (2-12), temperature (25-60 degrees C) and initial boron concentration (508,000 mg/L) were chosen as independent variables and coded x(1), x(2) and x(3) at three levels (-1, 0 and 1). Analysis of variance was used to test the significance of variables and their interactions with 95% confidence limit (alpha = 0.05). According to the regression coefficients, a second-order empirical equation was evaluated between the adsorption capacity (q(i)) and the coded variables tested (x(i)). Optimum values of the variables were also evaluated for maximum boron adsorption by vermiculite-HDTMA (HDTMA-Verm) and vermiculite-GA (GA-Verm).", "pred_label": "__label__POS", "pred_score_pos": 0.639017641544342}
{"content": "Most people are aware that Jesus spoke seven times from the cross. Those seven words are often the subject of Easter sermons. They depict Christ’s agony and his love for those about him. It is remarkable that when he spoke, he included concerns about those who are complicit to his murder. He asked the heavenly father to forgive them.\nThis week, being holy week, we are going to observe that his killers also spoke seven times to Christ. It was their intention to speak vile words to him and mock him. These seven sayings TO the cross were not spoken by faithful disciples or obedient followers.\nThese words were spoken during his agony when he should have only known devotion. Yet, through those lips God insisted that in some way truth be admitted by those who refused to believe in Christ. Therefore, these despicable people spoke two eternal truths.\nThese words are recorded in Matthew 27:39-42.\nThe first truth was that Jesus saved others. In the culmination of their hatred toward Jesus they recognized that he was the Savior of people. If they could only listen to themselves, they would come to believe in Christ because they said he was the Savior. What a contradiction of terms this was when these people standing on the ground and looking up to the cross yelled that he saved others. They may have meant this as a form of more mocking but was still true.\nHow dramatically wonderful it is that evil must admit the identity of Christ as the Savior. How beautiful it is that Jesus himself had the ability to forgive sins.During Christ’s ministry a man was lowered through a roof in a house so that Jesus could speak to his illness. He healed the man, but when Jesus was criticized for this healing, he pointed out that he also could save him from his sins which he did. The man was healed physically and spiritually.\nIt is almost beyond our imagination to grasp that the son of God, the second person of the Trinity, walked this earth and said to people, “I forgive you.” In a similar way today, whoever is open to hear those words and ask for forgiveness, Jesus will forgive.\nThe second truth is that he could not save himself.\nIn the garden of Gethsemane Jesus reminded his disciples that he could easily be rescued by calling 10,000 angels to defend him. The intention by the heavenly father and Jesus was not for him to live a harmonious life and then eventually die as an old man. The intention was that Jesus would be sacrificed for the sins of all mankind.\nChrist could not be the biblical sacrificial lamb for the sins of all mankind by coming down from the cross. His work would have been half finished. He performed his ministry for over three years and if he did not die on the cross, all would be in vain.\nWhat good would it be to have a Savior who saved himself and not have the means to save others? What good would it be to have a Savior who did not fulfill all the ancient prophecies? What good would it be to have a Savior who put himself before others? What good would be for Christ to obey those who ridiculed him and come down from the cross? What good would it be for Jesus to have faced the ridicule over all the years of his ministry? What good would it be for Christ to suffer all the pain that he did before his crucifixion and even the early parts of his crucifixion, if he came down from the cross?\nThe answer to these questions is that Jesus could not save anyone without his crucifixion and that if he came down from the cross, he would be accused of being a magician and a charlatan. He prophesied to his disciples that he would be crucified and he would be resurrected on the third day. He could not be resurrected without his death. He could not save himself!\nThe challenge to not save himself is directly tied to the salvation of all mankind as prophesied thousands of years ago. He has completed the course and the plan to be our Savior. Knowing what he did on the cross, how can we not accept him as our Savior and ask him to forgive us of our sins?", "pred_label": "__label__POS", "pred_score_pos": 0.5853947401046753}
{"content": "For the purposes of this short presentation (click here for slides), I will change some of my students’ names, but I will tell you of two distinct moments and disciplinary contexts in which I engaged with pedagogical approaches of multimodal composition. I make the distinction of pedagogical to emphasize how we as scholars also engage “feminist-oriented multimodal composition” in other kinds of work: such as this presentation.\nScene 1: Summer of 2015\nIn A FYW assignment, for a course I titled Exploring Cultural Literacies and Academic Writings: Khemi created a slide show of a cross-historical exploration of anti-Black Violence, while Shawn wrote, directed, recorded, and performed as a news-anchor focusing on Black Lives Matter.\nScene 2: Spring of 2018\nIn a Latina Feminist Studies course: Several students focused on Amara La Negra self-branding and promoting Afro-Latinidad / explored whiteness in Chicana queer identities & a bilingual TPS infographic to be circulated via tumblr.\nReflection:\nIn both instances, students critically analyzed and rhetorically expressed attention to performance and the intersections of gender, race, class, ethnicity, and sexuality.\nMeta:\nToday I will be talking about “Feminist Oriented Multimodal Composition Assignments” in distinct disciplinary contexts, embedded in a predominantly white institution, as potentially productive spaces of intersectional activism. Ultimately, I want to emphasize how multimodal composition assignments create spaces for embodied performance of knowledge in/and/through identity.\nHow are (inter)disciplinary comparative approaches forwarding claims about Composition’s significance beyond a first-year writing entrapment? Why is it important to focus on the writing that is done in Women’s and Gender Studies courses? How are we forwarding a claim of first-year writing as acultural?\nThe significance of questions about orientation in assigning multimodal assignments should be expanded from an attention of what it is that we are including as composition to why it is that we rely on multimodality: I’m thinking here of going from Shipka and Palmeri, to Banks, Hass, and Cedillo.\nThe Literature:\nIn my reflection here today, I specifically build on the work of:\nSarah Warren-Riley and Elise Verzosa Hurley’s “Multimodal Pedagogical Approaches to Public Writing” from Composition Forum (2017).\nThey explore critical multimodal pedagogical approaches to public writing, particularly focusing on “interrogating mundane, everyday texts” and their “potential to engage students with advocacy and its role in shaping public discourse.” In short, they explain “multimodal composition\nas advocacy.”\nWarren-Riley and Verzosa Hurley prioritize advocacy over activism, as the latter “connotes directed and specific action whereas advocacy simply implies support.”\nOn the other hand,\nCarmen Kynard’s “Staying Woke: Race-Radical Literacies in the Makings of a Higher Education” in a CCC-Symposium titled What Will We Have Made of Literacy (2018), she focuses more on the impetus for race-radical literacy practices, among them multimodal ones.\nShe distinguishes between race-radical and racial-liberalist notions of education, by using as an example Payton Head, “the former student body president and central activist in the University of Missouri’s (Mizzou’s) 2015 protests against campus racism and white violence.”\nBorrowing from Lani Guinier’s notion of racial literacy, I take my inspiration from Payton Head’s discourse and activism to delineate what I am calling race-radical literacies and a queering/que(e)r-ying of academic spaces, particularly our field’s relationship to a racially hostile academy. I gravitate to Guinier’s critiques of the racial liberalism surrounding Brown v. Board of Education that have sustained structural racism. (520)\nShe explains that in a presentation about Mizzou’s publicized racial tensions, “Payton Head’s black student activism was tokenized by co-panelists who did not seem to imagine that he would and could clap back.” (521)\nLingering Questions: How are (inter)disciplinary comparative approaches forwarding claims about Composition’s significance beyond the first-year writing entrapment? What are the implications of identity formation and performance for marginalized populations in predominantly white institutions? How is multimodal composition performing feminist activist work?", "pred_label": "__label__POS", "pred_score_pos": 0.7824430465698242}
{"content": "The economic and social consequences of the Covid-19 pandemic are far reaching and continuously evolving with the second lockdown recently announced. Whilst we are all living in a time of considerable uncertainty, market research professionals have an ongoing, important role to play in partnering clients in offering sound, evidence-based advice.\nFrom a public sector perspective, there is a critical need to understand community perceptions and behaviours to more closely match service provision with the developing needs of the population. Through genuine, open and consistent dialogue, we have found engagement can be very effective and result in actionable insight to take forward. Clients may not need the same information as before the pandemic but there are still important decisions to be made over the coming months, which should be made on evidence not assumption. Using iterative and sensitive research approaches, we have experienced a surge in response rates across methodologies with the majority being receptive to taking part in something that potentially makes a difference. We recently partnered Surrey County Council and Surrey Heartlands Health and Care Partnership in consulting residents to understand the impact of the pandemic to date via a large-scale postal survey with optional online completion. Response far exceeded initial expectations facilitating a thorough exploration of findings. As a research professional, this was the optimal scenario - significant engagement from residents and a robust dataset that allowed us to explore opinion at such a critical time. The sentiment of which was echoed amongst the client team and 60 stakeholders across Surrey via a Microsoft Teams debrief session.\n“ Lake’s professional approach to this Covid research project has been a key factor in its success. From the outset, they aimed to work with us to design a survey that was both comprehensive and inclusive, balancing the data requirements of teams in the NHS and local authority. By combining a postal methodology with a ‘push to web’ feature we managed to achieve a high response rate which has allowed us to perform a much deeper analysis than first envisaged. Throughout the project, Lake worked to understand the priorities of the multiple organisations with a stake in this project and ensure that these priorities were reflected in the final outputs. Consequently, the value of this project has far outweighed our original expectations.” Head of Research, Surrey County Council & Surrey Heartlands Health and Care Partnership\nOver the coming months, we will continue to partner our clients to understand how their requirements have changed and how we can help. We still have a critical role to play and are proud of our work making a difference to our clients and the communities they represent.", "pred_label": "__label__POS", "pred_score_pos": 0.6407070755958557}
{"content": "Housing affordability continues to be an issue for many Americans. Nearly 67% of Americans are bunkered down by at least one non-mortgage debt. SmartAsset analyzed data from the 50 largest cities to find where the average American can afford the largest home, along with the smallest. Data compared included median household income in each city, average non-mortgage debt, and median home values. The top three cities where Americans can afford the most home are Detroit, Memphis, and Oklahoma City. For the cities where Americans could afford the least home, New York City, Los Angeles, and San Francisco unsurprisingly took the top three spots.\nKey Findings Detroit and Oklahoma City stay affordable; Oakland becomes less affordable. Compared to last year’s analysis, Detroit and Oklahoma City still rank within the top three cities where the average household can afford the most home, with affordability ratios increasing to roughly 192% and 150%, respectively. Meanwhile, of the five cities where the average household can afford the least home, all but one are the same as last year: Long Beach, California moved out of the bottom five, replaced by Oakland, which jumped from sixth-worst in our 2019 study to fourth-worst in this year’s analysis. Some big-city dwellers with debt may struggle to afford a home. In 22 of the 50 cities in our study, households cannot afford the city’s median-valued home while paying off the average non-mortgage debt. In fact, the typical household with debt can only afford less than 50% of the median home value in three cities: New York, Los Angeles and San Francisco.", "pred_label": "__label__POS", "pred_score_pos": 0.8214778900146484}
{"content": "The Influence of Gene Polymorphisms on Tobacco and Alcohol-Induced Oral Cancer RisK Author(s) Otávio A. Curioni, Marcos B. de Carvalho, Rogério A. Dedivitis, Abrão Rapoport, Gilka J. F. Gattas ABSTRACT This study examined whether genetic polymorphisms of tobacco and alcohol-related metabolic genes such as GSTM1, GSTT1, GSTP1, CYP1A1, CYP2E1 and DNA repair genes (XRCC1 194Trp, XRCC1 399Gln, andXRCC3 Met) contribute to the risk of developing OSCC. Aims: Methods:Patients eligible for inclusion were over 18 years, had pathologically confirmed OSCC and were followed prospectively for at least two years or until death, from December 2000 to December 2004. Ninety-two OSCC patients were included along with 244 subjects from the same hospital, evaluated in the same period as patients without cancer, as the control group. Results:GSTM1 null and XRCC1-194Trp alone increased the risk of OSCC (OR, 2.15; 95% CI, 1.2 – 3.6 and OR, 2.02; 95% CI, 1.01 – 4.03, respectively). The joint effect of GSTM1 null with CYP1A1 or CYP2E1 polymorphism increased the risk two to threefold. Similar results were observed when XRCC1-194Trp was combined with GSTM1 null or the CYP2E1 polymorphism. By contrast, XRCC1- 399Gln was associated with protection against OSCC. Gene-gene and gene-environmental interactions were mainly detected for CYP1A1 andGSTP1 associated with more than 20 p/y of tobacco and XRCC1-194Trp when more than 30 g/L/d of alcohol was consumed (OR, 8.8; 95% CI; 1.3 – 45.7). Conclusions:The drug metabolizing and DNA repair enzyme polymorphisms may be informative for clinicians in the preventive management of patients at risk, particularly those with strong smoking and drinking habits. Scoliosis is a common condition in adult patients, and often causes chronic back pain compared to non-scoliosis. It has also been identified that bone mineral density is very often compromised in patients with scoliosis, even occurring in adolescence. At this time, no study has looked at how bone mineral density and scoliosis incidence or severity may be connected with specific regard to treatment. This study presents data on the outcomes of a scoliosis-specific exercise therapy and its ability to correct scoliotic curvatures in adult patients alone and in combination with bone mineral density supplementation. Methods: The charts of 14 total patients were retrospectively selected based upon specific inclusion criteria. Outcome assessments included the radiographic Cobb angle of the primary curvature, as well as laboratory measures of urinary deoxypyridinoline cross links. These results were compared against 12 patients who did not take the bone density supplement during or after their exercise-based treatment. Results: Patients taking the bone density supplement achieved the same level of Cobb angle reduction as compared to the control group. However, they additionally achieved a significant reduction in urinary deoxypyridinoline cross links as compared to the control group at 6 months. Conclusion: Patients taking a multi-ingredient bone density supplement daily for 6 months after completing a scoliosis-specific exercise program reported statistically significant improvements in urinary deoxypyridinoline cross links as compared to controls. It is unknown if or how bone density loss may contribute to the onset or progression of scoliosis. Long-term follow-up of these patients will be ongoing to assess bone mineral density status and Cobb angle changes longitudinally. Background:", "pred_label": "__label__POS", "pred_score_pos": 0.9586114883422852}
{"content": "Learning to Bear the Pain of Others: Biomedical and Theological Considerations of Vicarious Suffering Among Medical Trainees Charles Zimbrick-Rogers, M.D., Assistant Professor of Pediatrics, Naval Medical Center Portsmouth and the Uniformed Services University of the Health Sciences\nMany who enter a healing profession do so with a goal of alleviating suffering. However, engaging with the suffering of others may cause significant distress for medical trainees, and the phenomenon of secondary traumatization in medical providers is well documented. Spiritual and/or religious medical trainees may draw on the resources of their faith traditions in seeking to grapple with meanings and sources of suffering beyond biomedical etiologies. Minimal attention has been paid to the complex intersections of spirituality and medical training, particularly in regard to vicarious suffering experienced by medical trainees. This paper is a preliminary effort toward developing a theoretical framework for engaging this gap.\nThis paper is an autoethnographic engagement with my own experiences as a religious person, medical trainee, and now medical educator in dialog with the disparate worlds of biomedicine, anthropology, and theology. First, I explore the ways in which seeing and engaging with the suffering of others can, through a mechanism of secondary traumatization, lead to a reevaluation of the self and deeply held beliefs. Second, I attempt to complicate our understanding of trauma and secondary traumatization through engagement with Didier Fassin’s critique of the moral economy of trauma language and Shelly Rambo’s understanding of trauma as rupture. Third, I place my own experiences engaging with suffering people and medical trainees in conversation with Rambo’s understanding of pneumatological remaining in the face of trauma and Emmanuel Levinas’ understanding of approaching transcendence through the face of the Other. In this way, I propose a lived theology approach for thinking through the complexities of vicarious suffering in medical trainees. It is my hope that such an approach may prove fruitful in enabling medical educators to better support trainees in their own development as holistically healthy and empathetic practitioners.", "pred_label": "__label__POS", "pred_score_pos": 0.8684152960777283}
{"content": "3 to 4 pages\nless than 20% OV SCORE\nYou have attended a conference on the impact of substance abuse on relationships and families. You have been asked by your boss to develop a training packet for your agency’s in-service department.\nExplain the current theories of addiction and how those addictions affect the individual as well as the family (behaviorally, psychologically, physically, and socially).\nMany individuals often experience domestic violence from the substance abuser.\nIdentify the signs and patterns of domestic violence. Identify the treatment, prevention, and recovery resources that are available and the process for securing those resources.", "pred_label": "__label__POS", "pred_score_pos": 0.6192100048065186}
{"content": "Abstract\nBackground: A high rate of resistance to 3rd generation cephalosporins among Enterobacteriaceae isolates from Egypt has been previously reported. This study aims to characterize the resistance mechanism (s) to extended spectrum cephalosporins among resistant clinical isolates at a medical institute in Cairo, Egypt. Methods: Nonconsecutive Klebsiella pneumoniae (Kp), Enterobacter cloacae (ENT) and Escherichia coli (EC) isolates were obtained from the clinical laboratory at the medical institute. Antibiotic susceptibility was tested by CLSI disk diffusion and ESBL confirmatory tests. MICs were determined using broth microdilution. Isoelectric focusing (IEF) was used to determine the pI values, inhibitor profiles, and cefotaxime (CTX) hydrolysis by the β-lactamases. PCR and sequencing were performed using bla\nCTX-M and ISEcp1-specific primers, with DNA obtained from the clinical isolates. Conjugation experiments were done to determine the mobility of bla CTX-M. Results: All five clinical isolates were resistant to CTX, and were positive for ESBL screening. IEF revealed multiple β-lactamases produced by each isolate, including a β-lactamase with a pI of 8.0 in Kp and ENT and a β-lactamase with a pI of 9.0 in EC. Both β-lactamases were inhibited by clavulanic acid and hydrolyzed CTX. PCR and sequence analysis identified bla CTX-M-14. in Kp and ENT and a bla CTX-M-15 in EC. Both bla CTX-M-14 and bla CTX-M-15 were preceded by ISEcp1 elements as revealed by partial sequence analysis of the upstream region of the bla CTX-M genes. bla CTX-M-15 was transferable but not bla CTX-M-14. Conclusion: This is the first report of CTX-M-14 in Kp and ENT isolates from Egypt, the Middle East and North Africa. All Science Journal Classification (ASJC) codes Infectious Diseases", "pred_label": "__label__POS", "pred_score_pos": 0.7622079849243164}
{"content": "Abstract\nUrgent development of alternative on-farm killing methods for poultry is required following the number restrictions placed on the use of traditional manual cervical dislocation by European Legislation (EU 1099/2009). Alternatives must be proven to be humane and, crucially, practical in commercial settings with multiple users. We assessed the performance and reliability of a novel mechanical cervical dislocation device (NMCD) compared to the traditional manual cervical dislocation (MCD) method. NMCD was based on a novel device consisting of a thin supportive glove and two moveable metal finger inserts designed to aid the twisting motion of cervical dislocation. We employed a 2 × 2 factorial design, with a total of eight stockworkers from broiler and layer units (four per farm) each killing 70 birds per method. A successful kill performance was defined as immediate absence of rhythmic breathing and nictitating membrane reflex; a detectable gap in the vertebrae and only one kill attempt (i.e., one stretch and twist motion). The mean stockworker kill performance was significantly higher for MCD (98.4 ± 0.5%) compared to NMCD (81.6 ± 1.8%). However, the MCD technique normally used by the stockworkers (based previous in-house training received) affected the performance of NMCD and was confounded by unit type (broilers), with the majority of broiler stockworkers trained in a non-standard technique, making adaption to the NMCD more difficult. The consistency of trauma induced by the killing methods (based on several post-mortem parameters) was higher with NMCD demonstrated by “gold standard” trauma achieved in 30.2% of birds, compared to 11.4% for MCD (e.g., dislocation higher up the cervical region of the spine i.e., between vertebrae C0–C1, ≥1 carotid arteries severed), suggesting it has the potential to improve welfare at killing. However, the results also suggest that the NMCD method requires further refinement and training optimization in order for it to be acceptable as an alternative across poultry industry, irrespective of previous MCD technique and training.\nBibliographical note1024917 Keywords Animal welfare Cervical dislocation Killing Post-mortem Poultry Reflexes Agriculture, Horticulture And Engineering Sciences, Monogastric Science Research - Senior Behaviour and Welfare Scientist/Poultry Site Manager\nPerson: Academic contract that is both teaching and research", "pred_label": "__label__POS", "pred_score_pos": 0.5252177715301514}
{"content": "市場調查報告書\n全球冷凍食品市場 - 成長，趨勢，及預測:2020年∼2025年 Global Frozen Food Market - Growth, Trend, and Forecast (2020 - 2025) 出版商 Mordor Intelligence LLP 商品編碼 458467 出版日期 內容資訊 英文 124 Pages\n商品交期: 2-3個工作天內\n價格\n全球冷凍食品市場 - 成長，趨勢，及預測:2020年∼2025年 Global Frozen Food Market - Growth, Trend, and Forecast (2020 - 2025) 出版日期: 2020年04月01日 內容資訊: 英文 124 Pages\n冷凍食品市場，2018年從2941億9000萬美金，在2019年∼2024年間預測將以4.3％的年複合成長率成長。在2017年中，在歐洲最大地區市場區隔佔了市場約33.8％的佔有率。\n本報告提供全球冷凍食品市場的相關調查，市場機會，成長及阻礙因素，各類型、用途、冷凍技術、地區的市場分析，競爭情形，主要企業的簡介等資訊。\n※ 本網頁內容可能與最新版本有所差異。詳細情況請與我們聯繫。\nThe frozen food market was valued at USD 294.19 billion in 2018 and is expected to register a CAGR of 4.3%, during the forecast period (2019-2024). In 2017, Europe was the largest geographical segment of the market studied and accounted for a share of around 33.8% of the market.\nThe market is primarily driven by rising disposable income, the introduction of longer shelf life products, increasing impulse purchasing, and huge demand for frozen food products, due to the lack of time. The market evolved from selling raw foods, such as frozen meat, fish, vegetables, and fruits to prepared foods and frozen vegetable mixes (with meat, rice, and pasta), frozen desserts, and bakery products. Ice creams and cakes emerged as the leading product category in this market. The factors affecting the market's growth include flavors, including sweetness, fat content, and texture.\nFrozen food, in general, is the food that has been subjected to rapid freezing and is kept frozen until used. The frozen food market report (henceforth, referred to as the market studied) offers key insights into the latest developments. It analyzes the recent opportunities, drivers, and challenges affecting the market space for frozen food.\nDemand for Nutritious Frozen Desserts among Consumers\nMany consumers are increasingly looking for a convenient frozen dessert-based snack, which delivers health benefits, tastes good, and offers a healthy snacking experience. The dairy industry in this sector is able to offer products with minimal processing, and low sugar content (particularly beneficial for diabetic patients) for easy eating experiences that go beyond the traditional three-square meal experience (good and filling meal). Milk-based frozen desserts provide food rich in nutrients, like vitamin D, calcium, potassium, magnesium, and vitamin A. Milk-based snacks also add more calories, protein, and a number of vitamins and minerals. They can, therefore, provide positive nutrition and help reduce nutrition deficiency. The nutrients in dairy-based frozen products include calcium, vitamin D, phosphorus, potassium, and vitamin A. Further, calcium, phosphorus, and protein contained in ice creams, yogurts, etc. drive up the demand for these products among consumers.\nEurope to Dominate the Market\nEurope is the largest market for frozen food products, globally. Customers attitude toward frozen food has transformed significantly in Europe since the 1990s, driven by an improvement in living standards and an increasing need for convenience. Consumption level for frozen foods remains high across Europe, although the growth was rather limited in certain parts of the region during 2013-2016. This can be attributed to the intense competition the sector faces from chilled prepared foods, which are increasingly being perceived as foods that offer superior taste and quality, compared to their frozen equivalents. Recent evidence suggests that most manufacturers have been successful, as the frozen food market is back on the growth trajectory in countries, such as the United Kingdom, France, and Germany.\nThe frozen food market is a highly fragmented market and comprises of regional and international competitors. The market is dominated by players, like Unilever, Nestle SA, General Mills, Nomad Foods Ltd, Tyson Foods Inc., and Conagra Brands Inc. The leading players in the frozen food market enjoy a dominant presence worldwide. These players focus to leverage opportunities posed by emerging markets to expand their product portfolio so that they can cater to the requirements for various product segments, especially frozen desserts. Companies compete on different factors, including product offerings, ingredients, quality, taste, flavors, price, functionality, size, packaging, and marketing activities, in order to gain the competitive advantage in the market.", "pred_label": "__label__POS", "pred_score_pos": 0.7810471653938293}
{"content": "The Department of Health and Human Services (HHS) Office of Inspector General (OIG) has increased its focus on healthcare fraud schemes involving telehealth services. The OIG began this increased focus in 2016. These efforts contributed to a massive takedown in September.\nIn this enforcement effort, the OIG arrested and charged 345 individuals including medical practitioners, pharmacy owners and telemedicine executives. The prosecution has accused these individuals of participating in healthcare fraud schemes that cost the government over $6 billion in losses. The OIG reports more than $4.5 billion of these loses are connected to telehealth services.\nWhat were the allegedly fraudulent telehealth services?\nAccording to the government, those involved in the alleged scheme were using \"aggressive marketing\" techniques to increase revenue. Examples include the use of telemarketing calls and internet advertisements. The prosecution has accused those running the scheme of paying medical providers to order medical equipment, testing and medications that were not medically necessary.\nTo make matters even worse, the government has accused these executives of using shell corporations and foreign bank accounts to launder the money - to remove the money from the alleged criminal activity. If evidence is present to support these allegations, in addition to healthcare fraud charges those involved could also face criminal charges for money laundering and, depending on the timing and details of tax reporting, tax crimes.\nWhat can telehealth providers learn from this sting?\nMedical professionals who are using telehealth services should see this enforcement operation as a call to action. The current pandemic has led to a sharp increase in the reliance of telehealth services. As such, medical professionals, pharmacists and other healthcare providers who were used to in-person appointments may find themselves navigating new methods to provide healthcare.\nThose who are unfamiliar with this type of healthcare, and even those who have used it in the past, are wise to proactively conduct an audit to see if there are any concerns that the group may run afoul of applicable regulations. This audit can help to catch an issue before it becomes a larger problem. A failure to do so could result in a cascading issue that leads to a federal investigation and charges of criminal wrongdoing.", "pred_label": "__label__POS", "pred_score_pos": 0.9096523523330688}
{"content": "Over the course of the next few years, after meeting this legend and his amazing brother in arms, Bill Clark (both so graciously mentoring me), the work we now do at the American Sleep Apnea Association is a product of their combined influence: innovation and evolution of our Sleep Health Patient Community, now and into the future.\nThose with COPD struggle to maintain a healthy balance of oxygen and carbon dioxide in their bloodstream during the day. If they also have OSA, this sleep breathing disorder kicks in as soon as they fall asleep, leading to further stresses to their blood chemistry. While the rest of us rely on that nighttime period of consolidated sleep to maintain health and well being, and to recover from the stresses placed on oursystems by chronic illness, those with Overlap Syndrome never catch a break. This explains the term “overlap syndrome.” It’s a way to reference the never-ending challenges of breathing for those suffering from both COPD and OSA.", "pred_label": "__label__POS", "pred_score_pos": 0.7034603357315063}
{"content": "My Ex Filed a Petition to Modify Child Support, What Do I Do?\nWhen you are served with a petition to modify an existing child support order, you may panic with fear regarding the loss of the financial support that provides for the needs of your child. However, it is important to understand the statutory requirements of a modification and aid your case by employing a knowledgeable Pensacola Child Support Attorney to ensure your rights are protected.\nIf you are the recipient, or an obligated party involved in an existing child support order, you may file a supplemental petition to modify this order with a showing of a substantial change in circumstances. However, this substantial change is generally a difficult bar to overcome as the Florida Legislature wishes to protect minor children and requires adequate financial aid be provided to support the child’s necessary living expenses. Therefore, when you are provided with a petition to modify an existing child support order, do not panic. Instead, begin by reviewing the grounds your co-parent noted as the substantial change in circumstances warranting the modification.\nIn general, substantial changes consist of loss of income, change in custody or visitation, or a significant medical diagnosis. Florida statute provides a presumption of substantial change when the support amount provided for the child, as calculated by the child support guidelines, would increase or decrease by 15% or $50. This support amount can change due to the expenses relating to the child, or the income of the parties having significantly increased or decreased. For instance, if a child has recently been diagnosed with a medical condition resulting in full time care, medical appointments, or educational needs the expenses will inevitably increase which may require more financial support.\nFurther, the support amount may change due to the increase or decrease of income received by a party. However, courts are reluctant to modify child support if the decrease in income of a party was due to voluntary action. For instance, if your co-parent has voluntarily taken a position with a lesser salary, or engaged in voluntary conduct resulting in their termination, this form of decrease in income will not be accepted by the court. However, if the income decrease was a result of an involuntary act and the parent has actively attempted to obtain subsequent and equal employed with no result, or the parent’s income decrease was a result of a medical disability or diagnosis, the court may modify this obligation.\nFinally, Florida Statute provides an avenue for modification of a child support when there has been a deviation in the parenting time exercised by the parties. For example, if the non-custodial parent is exercising 20% or more of the overnights in a year, the child support order should deviate from the child support guidelines in relation to the amount of time the non-custodial parent shares with the child.\nModification procedures can be overwhelming when attempting to retain the financial security for the benefit of your child. To ease your concerns, seek the guidance and counsel of an experienced Pensacola Child Custody Attorney. They will be able to thoroughly explain the modification procedures, negotiate a settlement, or argue your case before a court to protect your rights.\nSpeaking to an attorney at our Pensacola office is free of charge, and we accept calls 24 hours a day, 7 days a week. Contact us at 850-999-5857 or complete an online contact form to get in touch with a member of our team today.", "pred_label": "__label__POS", "pred_score_pos": 0.9780300855636597}
{"content": "NACCHO Solicits Model Practices and Innovative Practice Award Applications\nThe National Association of County and City Health Officials (NACCHO) has opened the application process for 2021 Model Practices and Innovative Practice Awards. Each year, NACCHO’s\nModel Practices Program nationally honors and recognizes outstanding local public health practices and shares them through the Model Practices Database. These practices are rigorously reviewed by a committee of peers, consisting of other local health department professionals, and selected from a competitive pool of applicants.\nThe Model Practices Program application is strongly recommended to LHDs if a practice demonstrates exemplary and replicable outcomes in response to an identified public health need and it reflects a strong local health department role, collaboration, innovation, sustainability, and a thorough evaluation.\nThis year, amid the COVID-19 pandemic, a new Innovative Practice Award application will run concurrently with the Model Practices Program application. The Innovative Practice Award was created to recognize outstanding practices that have been created or significantly adapted in response to COVID-19.\nThe Innovative Practice Award application is strongly recommended to LHDs if a practice was developed in response to the COVID-19 pandemic or if a practice was creatively adapted to meet the circumstances of the COVID-19 pandemic and the practice demonstrates remarkable innovation to address COVID-19 but does not yet exhibit the same rigorous program evaluation or long-term sustainability as a Model Practice.\nThe application period for the 2021 Model Practices Program and 2021 Innovative Practice Award will open November 2, 2020, and close December 31, 2020. NACCHO will hold an informational webinar on the opportunities on Thursday, November 5 at 11:00 am PT.", "pred_label": "__label__POS", "pred_score_pos": 0.8662878274917603}
{"content": "Sexual harassment is defined by New York law as unwelcome conduct that is of a sexual nature, which includes both verbal and physical actions. Employers are most frequently involved in the following forms of sexual harassment acts: demanding sexual favors in exchange for promotions, creating a sexually offensive work environment, and making sexual advances.\nHow does New York Law Prohibit Sexual Harassment?\nFirst, Wantagh employers can be required to create company policies that specifically address sexual harassment in the workplace. These must be posted in a visible area such as a break room. Company polices might include such matters as contact information to be used in reporting sexual harassment, filing policies, and remedial measures in the event that a claim is proven to be true.\nFurthermore, federal and New York laws create specific agencies which are responsible for handling sexual harassment cases. The agencies are given authority to investigate workplaces in Wantagh to determine if the incidents alleged in the complaints they receive are true. Employers are also barred under these laws from taking action in retaliation against an employee who has claimed sexual harassment, such as firing them or denying them a promotion.\nHow can a New York attorney help?\nIt can be difficult to both investigate and establish a sexual harassment claim without having any expertise in the applicable areas of law. Federal investigators are often extremely overworked. Because of this, working with a Wantagh attorney may be the ideal way to make sure that your claim is processed in a timely manner.", "pred_label": "__label__POS", "pred_score_pos": 0.7782149314880371}
{"content": "Abstract\nThiamine hydrochloride (Vitamin B\n1, THCl) can exist as a nonstoichio-metric hydrate (NSH) and as a hemihydrate (HH). NSH can contain up to ∼1 molar equivalent of water and be dehydrated to an isomorphic desolvate (ID) with minimal change in lattice structure. Crystallographic and spectroscopic techniques were used to characterize the influence of structure and mobility on NSH dehydration. Dehydration was accompanied by lattice contraction, as noted by a decrease in the d-spacings. Dehydration also led to the development of surface cracks parallel to the (101̄) and (102̄) planes in the NSH single crystal, as observed by hot stage microscopy. Step-wise dehydration of NSH produced gradual shifts in XRPD and SSNMR peaks, indicating that NSH (with ∼1 mole water) and ID represent the two extremes of a continuum in the hydration state. Variable temperature 13C SSNMR studies showed that water molecules move rapidly at room temperature within the NSH crystal lattice, and the thiamine molecules transiently exist in distinct hydrated and dehydrated states. It is hypothesized that, despite the lack of continuous hydration channels in the NSH crystal lattice, cooperative deformation of the thiamine molecules allows a nondisruptive departure of water molecules from the lattice during dehydration. Keywords Crystal structure Hydrates Mobility Solid-state NMR Spectroscopy X-ray powder diffractometry", "pred_label": "__label__POS", "pred_score_pos": 0.5192266702651978}
{"content": "As a new mom you feel like you need everything. It feels like there's a million products and a thousand options even within one category. Building our registry was fun, but it was also stressful. I wanted to be wise with the investment, get the best, and not clutter up my house more than necessary [...]\nRight before Christmas we took a family trip to Aruba. It was incredible, but pregnancy made it a bit more interesting. My dad booked the trip in April 2019 - three months before we even knew we were pregnant. I was bummed to miss out on the delicious all-inclusive drinks, but I was determined to [...]\nI'm currently 27 weeks pregnant. At this point, I'm not new to pregnancy, but also have more time to go before baby girl makes her arrival into the world. I have some thoughts about pregnancy and interactions with others. It's not one of those things we've been necessarily trained on how to handle, so this [...]\nI want to begin this by recognizing those that are struggling with infertility, loss, and any other heartache surrounding pregnancy. I cannot imagine what that hurt feels like. I'm praying for you. The pain you're experiencing is real and your feelings are valid. Please seek the help you need. You're not alone. I don't say [...]\n“How are you feeling?” I’m asked this question at least once a day. I greatly appreciate how much people genuinely care about how we’re doing (me and baby), but I’m finding it’s hard to truly answer this question. I’m challenged to sum up how I’m feeling in the expected 10 second response window. I can’t. [...]", "pred_label": "__label__POS", "pred_score_pos": 0.8660913109779358}
{"content": "Oil and gas businesses employ millions of workers. Every worker, from the most junior to the most senior, has a right to a safe, secure workplace. If they allege the company mismanaged their employment, the company could lose out. With the appropriate liability insurance, namely employment practices coverage, you can respond to charges leveled against you. What’s this coverage? Why is it important within your industry?\nYour employees range from rig managers to high-level executives. They all could feel mistreated during in the workplace. Use your liability coverage to respond to these charges.\nWhat’s EPLI coverage?\nEmployment Practices Liability Insurance (EPLI) pertains to mistakes made by companies in the course of hiring or retention. All employees have a right to fair employment. Therefore, should the company act incorrectly, the affected parties might have a claim against the business. Given that the oil and gas industry has as many employees as any other business, coverage is critical.\nLet’s say that a rig employee alleges that a manager created an abusive and harassing atmosphere. That’s likely in breach of certain employment laws. As a result, the employee might file a lawsuit against the company and the suspect parties. EPLI coverage can step in here.\nAn EPLI policy might help you cover fees, settlements and judgements following suits. Thus, you will place your business in a more secure position. You’ll also be able to better compensate those wronged by your actions or inaction.\nEstablishing the appropriate protection\nAll businesses are individual entities, even within the oil and gas industry. So, the EPLI coverage yours needs might differ from that of your nearest competitors. Consider some of these guidelines to help you establish the appropriate coverage.\nDetermine which employees should have coverage under the policy. These might range from high-level executives to volunteers. As a rule of thumb, insure all those who might play a role in hiring or termination. Consider the employment practices within your business. How does your hiring or termination process work? Does this increase the potential for an EPLI claim? Think about some of the claims that might arise. Could someone allege sexual misconduct? What about infliction of emotional distress or improper reviews? Does your policy effectively address these potential risks? If it doesn’t, you might need to adjust more coverage. Choose appropriate limits and deductibles for the value of your business. Examine the average claim cost in your industry. Adjust coverage to create as much financial protection as you can.\nYou don’t have to be an expert on EPLI coverage to get the right policy. Instead, provide your agent with a full description of your operating risks. That will help them determine the best way to insure you.", "pred_label": "__label__POS", "pred_score_pos": 0.5779275298118591}
{"content": "Lari, P., Rose, A., Ernst, J. V., Kelly, D. P., & DeLuca, V. W. (2019). Action research. Technology and Engineering Teacher, 79(2), 23-27.\nResearch questions should be concise, such as: o How do students understand the concept of constraints as it affects engineering design? o To what extent does classroom instruction align with workplace readiness skills? o Will students' understanding of engineering constraints be improved by using a jigsaw method of cooperative learning? o How does a group design activity affect the individual accountability of students? o Is role assignment an effective strategy in the classroom for encouraging female participation in technology-related activities? Qualitative data may be gathered by video recording student activities, conducting in-depth interviews with students or parents, making direct observations of student behavior and taking notes, or conducting a thematic review of student assignments and journals or archival school documents. [...]qualitative data is fundamentally descriptive in nature and is expressed in narratives, visuals, and videos. Qualitative Data Analysis and Interpretation: Since qualitative data is expressed in narratives, images, and videos, the analysis of qualitative data typically requires an extensive analysis process consisting of transcription, iterative thematic review, coding text, data visualization, seeking additional sources of information that confirms emerging conclusions, and external validation from an independent evaluator. An examination of the descriptive statistics for Strategy A (M=38, SD=6.2) and Strategy B (M=38.5, SD=6.5) also suggests the advantage to Strategy B. Yet, only by using more sophisticated statistical procedures, such as a t-Test or Mann-Whitney U, could the teacher-researcher confirm that this difference in average scores did not occur by chance or error and then conclude that Strategy B is better than Strategy A. Even seasoned researchers seek assistance from statisticians and evaluators to help with data analysis, so don't hesitate to seek assistance from colleagues with these analytical tasks.", "pred_label": "__label__POS", "pred_score_pos": 0.6443705558776855}
{"content": "Many projects are not managed well, overspend and take longer than planned. Sometimes, there are good reasons for this. However, often, the reason for poor performance is a lack of structure and standardised systems.\nTo help address this, I have been developed tools and a guide and have put this together as a short online course. The course is particularly aimed at government officials working on infrastructure and social projects but may is relevant for people working on projects generally. It aims to be practica and includes templates and checklists that can be adapted by project managers for their situation and projects. Please contact me if you you would like more information.", "pred_label": "__label__POS", "pred_score_pos": 0.975244402885437}
{"content": "Abstract\nBackground: Adults with repaired tetralogy of Fallot (rTOF) are at increased risk for ventricular tachycardia (VT) due to fibrotic remodeling of the myocardium. However, the current clinical guidelines for VT risk stratification and subsequent implantable cardioverter-defibrillator deployment for primary prevention of sudden cardiac death in rTOF remain inadequate. Objective: The purpose of this study was to determine the feasibility of using an rTOF-specific virtual-heart approach to identify patients stratified incorrectly as being at low VT risk by current clinical criteria. Methods: This multicenter retrospective pilot study included 7 adult rTOF patients who were considered low risk for VT based on clinical criteria. Patient-specific computational heart models were generated from late gadolinium enhanced magnetic resonance imaging (LGE-MRI), incorporating the individual distribution of rTOF fibrotic remodeling in both ventricles. Simulations of rapid pacing determined VT inducibility. Model creation and simulations were performed by operators blinded to clinical outcome. Results: Two patients in the study experienced clinical VT. The virtual hearts constructed from LGE-MRI scans of 7 rTOF patients correctly predicted reentrant VT in the models from VT-positive patients and no arrhythmia in those from VT-negative patients. There were no statistically significant differences in clinical criteria commonly used to assess VT risk, including QRS duration and age, between patients who did and those who did not experience clinical VT. Conclusion: This study demonstrates the feasibility of image-based virtual-heart modeling in patients with congenital heart disease and structurally abnormal hearts. It highlights the potential of the methodology to improve VT risk stratification in patients with rTOF.\nKeywords Arrhythmia Computer simulation Electrophysiology Magnetic resonance imaging Tetralogy of Fallot Ventricular tachycardia ASJC Scopus subject areas Cardiology and Cardiovascular Medicine Physiology (medical)", "pred_label": "__label__POS", "pred_score_pos": 0.6112344264984131}
{"content": "Arachidonic acid (ARA) is metabolized by cyclooxygenase (COX) and cytochrome P450 to produce proangiogenic metabolites. Specifically, epoxyeicosatrienoic acids (EETs) produced from the P450 pathway are angiogenic, inducing cancer tumor growth. A previous study showed that inhibiting soluble epoxide hydrolase (sEH) increased EET concentration and mildly promoted tumor growth. However, inhibiting both sEH and COX led to a dramatic decrease in tumor growth, suggesting that the contribution of EETs to angiogenesis and subsequent tumor growth may be attributed to downstream metabolites formed by COX. This study explores the fate of EETs with COX, the angiogenic activity of the primary metabolites formed, and their subsequent hydrolysis by sEH and microsomal EH. Three EET regioisomers were found to be substrates for COX, based on oxygen consumption and product formation. EET substrate preference for both COX-1 and COX-2 were estimated as 8,9-EET > 5,6-EET > 11,12-EET, whereas 14,15-EET was inactive. The structure of two major products formed from 8,9-EET in this COX pathway were confirmed by chemical synthesis:\nct-8,9-epoxy-11-hydroxy-eicosatrienoic acid ( ct-8,9-E-11-HET) and ct-8,9-epoxy-15-hydroxy-eicosatrienoic acid ( ct-8,9-E-15-HET). ct-8,9-E-11-HET and ct-8,9-E-15-HET are further metabolized by sEH, with ct-8,9-E-11-HET being hydrolyzed much more slowly. Using an s.c. Matrigel assay, we showed that ct-8,9-E-11-HET is proangiogenic, whereas ct-8,9-E-15-HET is not active. This study identifies a functional link between EETs and COX and identifies ct-8,9-E-11-HET as an angiogenic lipid, suggesting a physiological role for COX metabolites of EETs. Keywords: angiogenesis; cyclooxygenase; epoxyeicosatrienoic acids; metabolism; omega-6 fatty acids.", "pred_label": "__label__POS", "pred_score_pos": 0.9337579011917114}
{"content": "T-cell acute lymphoblastic leukemia (T-ALL), a T-cell malignant disease that mainly affects children, is still a medical challenge, especially for refractory patients for whom therapeutic options are scarce. Recent advances in immunotherapy for B-cell malignancies based on increasingly efficacious monoclonal antibodies (mAbs) and chimeric antigen receptors (CARs) have been encouraging for non-responding or relapsing patients suffering from other aggressive cancers like T-ALL. However, secondary life-threatening T-cell immunodeficiency due to shared expression of targeted antigens by healthy and malignant T cells is a main drawback of mAb-or CAR-based immunotherapies for T-ALL and other T-cell malignancies. This review provides a comprehensive update on the different immunotherapeutic strategies that are being currently applied to T-ALL. We highlight recent progress on the identification of new potential targets showing promising preclinical results and discuss current challenges and opportunities for developing novel safe and efficacious immunotherapies for T-ALL.\nKeywords: T-cell acute lymphoblastic leukemia; chimeric antigen receptor; immunotherapy; leukemia-initiating cells; monoclonal antibodies; relapse.", "pred_label": "__label__POS", "pred_score_pos": 0.8276336789131165}
{"content": "1. We have previously shown that Xenopus spinal motoneurons make both chemical and electrical synapses with neighboring motoneurons. Because motoneurons are active during swimming, these synapses would be expected to contribute excitation to their neighbors. The significance of central motoneuron to motoneuron synapses was therefore investigated by analyzing the composition of the fast on-cycle excitation underlying spiking activity during fictive swimming in spinal motoneurons. To accomplish this we developed a method for very local application of drugs around a caudal recorded neuron while still being able to evoke and record essentially unaltered fictive swimming rostrally. 2. Intracellular recordings were made from spinal motoneurons during fictive swimming. Bicuculline (40 microM) and strychnine (2 microM) were used continuously to block inhibitory potentials locally around the motoneurons. The amplitude and duration of the fast excitation underlying spiking activity was measured before and during local applications of excitatory antagonists. 3. The nicotinic antagonists d-tubocurarine (10 microM) and dihydro-beta-erythroidine (10 microM) reduced the amplitude of this excitation by approximately 20%. Nicotinic antagonists also reduced the duration of this fast on-cycle excitation. The kainate/alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) antagonist 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX, 10 microM) reduced the amplitude (by approximately 30%) but not the duration of the on-cycle excitation. In the presence of 100 microM Cd2+, which blocks all chemically mediated transmission, a considerable amount (50%) of on-cycle excitation remained. 4. These results suggest that 20% of the on-cycle excitation comes from activation of nicotinic receptors by naturally released acetylcholine (ACh), presumably from other motoneurons.(ABSTRACT TRUNCATED AT 250 WORDS)", "pred_label": "__label__POS", "pred_score_pos": 0.7682417035102844}
{"content": "dc.contributor.advisor Weible, Michael dc.contributor.author Toppinen, Kelly Marie dc.date.accessioned 2018-01-23T02:23:01Z dc.date.available 2018-01-23T02:23:01Z dc.date.issued 2016 dc.identifier.doi 10.25904/1912/577 dc.identifier.uri http://hdl.handle.net/10072/365832 dc.description.abstract Adult neurogenesis in the subventricular zone (SVZ) is a highly dynamic and finely-tuned process, subject to modulation by various physiological stimuli. Fast- dividing transit-amplifying (type C) cells are the immediate progeny of adult neural stem cells in the SVZ. These type C cells play a key role in neurogenesis by expanding cell numbers that eventually give rise to neuroblasts destined for the olfactory bulbs (OB). The size of the progenitor pool, and ultimately the number of neurons that engage in synaptic competition at the OB, is largely determined by the balance between proliferation and differentiation of these cells. Identifying the signalling mechanisms that regulate type C cell fate is an essential step towards understanding how intermediate progenitor pools are maintained in the adult neurogenic niches. A key feature of type C cells is their transient expression and activation of epidermal growth factor receptor (EGFR), which is a critical signal involved in regulating their undifferentiated and proliferative state in vitro, and in maintaining the number of neurons produced in vivo. EGFR activation leads to multiple complex signal transduction pathways, including Ca2+ liberation from the endoplasmic reticulum (ER). Biological systems can transduce information by initiating and/or altering the spatial and temporal dynamics of Ca2+ within the cell, allowing for distinct biological signals to be transmitted in a process known as Ca2+-encoding. In this study, the role Ca2+-encoding plays in EGFR signal transduction was examined. dc.language English dc.publisher Griffith University dc.publisher.place Brisbane dc.rights.copyright The author owns the copyright in this thesis, unless stated otherwise. dc.subject.keywords Adult neurogenesis in the subventricular zone dc.subject.keywords Fast- dividing transit-amplifying (type C) cells dc.subject.keywords C-cells dc.subject.keywords Epidermal growth factor receptor dc.title EGFR Activates NFAT3 through Frequency Modulated Ca2+ Oscillations to Regulate the Proliferation of Transit-Amplifying (type C) Cells in the Adult SVZ dc.type Griffith thesis gro.faculty Science, Environment, Engineering and Technology gro.rights.copyright The author owns the copyright in this thesis, unless stated otherwise. gro.hasfulltext Full Text dc.contributor.otheradvisor Mackay-Sim, Alan dc.rights.accessRights Public gro.identifier.gurtID gu1490755104785 gro.thesis.degreelevel Thesis (PhD Doctorate) gro.thesis.degreeprogram Doctor of Philosophy (PhD) gro.department SChool of Natural Sciences gro.griffith.author Toppinen, Kelly M.", "pred_label": "__label__POS", "pred_score_pos": 0.6862590312957764}
{"content": "Abstract\nSubstance misuse services need to meet the growing demand and needs of individuals using new psychoactive substances (NPS). A review of the literature identified a paucity of research regarding NPS use by these individuals and UK guidelines outline the need for locally tailored strategies. The purpose of this qualitative study was to identify and explore key themes in relation to the use of NPS by individuals receiving community treatment for their substance use. Electronic records identified demographics and semi-structured interviews were undertaken. A thematic analysis of transcripts identified a variety of substance use histories; 50% were prescribed opiate substitutes and 25% used NPS as a primary substance. All were males, age range 26–59 years (SD = 9), who predominantly smoked cannabinoids and snorted/injected stimulant NPS. The type of NPS used was determined by affordability, availability, side-effect profile and desired effects (physical and psychological: 25% reported weight loss as motivation for their use). Poly-pharmacy, supplementation and displacement of other drugs were prevalent. In conclusion, NPS use and associated experiences vary widely among people receiving substance use treatment. Development of effective recovery pathways should be tailored to individuals, and include harm reduction strategies, psychosocial interventions, and effective signposting. Services should be vigilant for NPS use, “on top” use and diversion of prescriptions.\nBibliographical note© 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access\narticle distributed under the terms and conditions of the Creative Commons Attribution\n(CC BY) license (http://creativecommons.org/licenses/by/4.0/).", "pred_label": "__label__POS", "pred_score_pos": 0.8993270397186279}
{"content": "“Then the offering of Judah and Jerusalem will be pleasant to the Lord, as in the days of old, as in former years.”—Malachi 3:4\nPassover, Shavuot, and Sukkot are the three pilgrim feasts when the Jewish people would journey from their homes to Jerusalem in order to bring an offering to the Lord.\nCan you imagine the commitment of this journey? It was a long, tiring, and arduous task that required great commitment and sacrifice. But it was worth it!\nObedience is always worth the sacrifice.\nIt was very important for each family to bring a gift to the Lord during the Pilgrim Feasts. They were sowing an offering in obedience and believing for provision for the rest of the year.\nTheir seed was an investment into their future.\nThese men and their families understood that if they gave God what little they had, He would give them what they needed in the days and years to come.\nI know that the phrase “name it and claim it” has been overused and perhaps abused in the past several years, but I truly believe in naming your seed and expecting something good from our Father in return. Obedience releases blessing!\nConsider the promises of Malachi 3:10-12. I challenge you to claim these promises over the next offering you bring to the Lord, and have faith for a return:\n1.\n“Try Me now in this…” (vs. 10.) We decree and declare that the windows of Heaven are open above you, your family, your ministries and your businesses!\n2.\n“…and pour out for you such blessing that there will not be room enough to receive it.” (vs. 10.) We decree and declare that the blessings of the Lord will overtake and overflow you!\n3.\n“And I will rebuke the devourer for your sakes…” (vs. 11.) We decree and declare that the devourer is rebuked for your sake and the sake of your family!\n4.\n“…so that he will not destroy the fruit of your ground…” (vs. 11.) We decree and declare that Satan will not destroy the fruit of your ground; neither shall your vine cast its fruit in the field before its time! We decree that God’s perfect timing will be evident in your life!\n5.\n“…and all nations will call you blessed.” (vs. 12.) We decree and declare that all the nations shall call you blessed, for you shall be a delightful land!\nIt is time for us to trust in the Lord, march forward, and sow toward where we want go! It is time for us to decree a return! Sow in faith during this Passover season and throughout the coming year!\nInvest in your future!", "pred_label": "__label__POS", "pred_score_pos": 0.9405325055122375}
{"content": "Abstract\nSeveral parameters used in formation evaluation based on downhole logs are ultimately determinable only from measure- ments made on core samples. Consequently, the precision with which a log can be interpreted quantitatively depends on the precision with which the parameters such as cement- ation exponent, m, and saturation exponent, n, can be determined.", "pred_label": "__label__POS", "pred_score_pos": 0.7563597559928894}
{"content": "A railroad accident can permanently change your life. Accidents involving heavy, speeding trains often result in catastrophic loss, including severe injuries or death and environmental damage. Usually, negligence is the cause of these devastating accidents. We believe you deserve compensation from the careless person or company who has harmed you or your family in this way.\nThe attorneys at Morey Law Firm P.A. are prepared to represent you in claims that include:\nRailroads and their insurance companies maintain substantial legal teams poised to avoid their responsibility to you in the chaotic aftermath of a train accident. We match their calculated efforts with unshakable determination to win rightful compensation for you. We compete with these industry interests by drawing on our extensive knowledge about federal regulations, transportation requirements, labor law, personal injury, civil litigation and mediation. We are passionate about conducting a thorough investigation into the causes of the railroad accident and the extent of your injuries, and we are bolstered by our team of trauma doctors, chiropractors, forensic engineers, railroad engineers and accident reconstruction analysts who have expert understanding of the railroad industry and train mechanics.", "pred_label": "__label__POS", "pred_score_pos": 0.9734601378440857}
{"content": "The Financial Conduct Authority on Wednesday released guidelines for the Finance Ministry in the UK on how to regulate cryptocurrencies. Reportedly, the Ministry welcomed the guidance and was planning to consult on ‘unregulated cryptocurrencies’ later this year.\nThis was a monumental event in the UK’s Financial System as they attempted at a classification of different types of cryptocurrencies – ‘Token Taxonomy.’ The Authorities broadly viewed three kinds of crypto-assets: cryptocurrencies as a medium of Exchange, utility tokens and security tokens.\nStablecoins and Security Tokens to Be Formalized Soon?\nThey recognized ‘stablecoins’ backed by FIAT, as crypto which\ncould be regulated as e-money. The guidelines added,\nRespondents agreed that certain types of tokens can meet the definition of e-money and so fall under the EMRs\nNevertheless, these are some types of stablecoins like ones backed by a commodity or a basket of currencies and commodities. While Facebook’s Libra wasn’t mentioned explicitly, it was indicated that depending on the assets and the ecosystem that Libra builds it could be regulated as a security, a debt instrument, or other types of specified investments.\n‘Security tokens‘ issued on the blockchain were to broadly accepted to be regulated under RAO (Regulated Activities Order).\nUnregulated Exchange and Utility Tokens\nThe FCA broadly accepted that cryptocurrencies that are not issued or controlled by a central authority would be classified under ‘unregulated cryptocurrencies’ as they do not fall under the purview of existing laws. These include Exchange currencies like Bitcoin and even utility tokens like Ethereum.\nLast but not least, ‘utility tokens’ were defined as cryptocurrencies “that do not grant holders rights that are the same as those granted by specified investments.” While some them might be classified as e-money, the FCA largely agreed on putting utility tokens in the unregulated section.\nMoreover, the FCA also raised concerns around the dubious activities conducted on Exchange or trade platforms. The FCA told the media,\n“A combination of market immaturity, volatility, and a lack of credible information or oversight raises concerns about market integrity, manipulation and insider dealing within crypto-asset markets,”\nRegulatory Watchdogs all across the world are starting to consider cryptocurrencies as a serious issue. While the current market capitalization is considerably low, the retail business is quickly adopting this technology.\nFurthermore, even US lawmakers noted in the Senate Hearing held the day before that, US Cannot Ban Crypto Even If They Decide To. The finalized laws and guidelines on them can be expected from both Governments within the next year.\nDo you agree with the classifications drawn by the FCA? Please share your views with us.", "pred_label": "__label__POS", "pred_score_pos": 0.9786279201507568}
{"content": "Massacre of the Dreamers is crucial literature for any activist in the 21st century, as Castillo searingly navigates through the century-old roots of oppression at the heart of the Americas: the oppression of the brown woman.\nCastillo not only details the layers of misogynist systems which brown women have faced throughout their existence, but she also manages to cast a vision for those of us who want to be allies of Xicanisma –Chicana-based feminist consciousness — as we seek to free ourselves from our own internalized oppression.\nSteeped with fact-based analysis but not overwhelmingly focused on numbers, the book is also a model for what academic literature should be: based on the present conditions faced ‘on the ground’ by non-academics, since the majority of the working class which so many scholars hope to advocate for have neither the time nor the patience to sift through jargon-laden writing aimed at other academics.\nM.O.D was published in 1995, but is as relevant now as it was during the nineties for its careful examination of events like the Chicano Student walkouts of East Los Angeles in 1968, subsequent movements for economic justice such as the 1986 Watsonville Women’s Strike, and the form which the movement has taken more recently in events such as the Mujeres Activas en Letras y Cambio Social (MALCS) conference.\nFor its words of wisdom, sources, and its persistence in seeking ways to identify and dismantle systems of inequality, I absolutely recommend Ana Castillo’s book for anyone looking to learn about the Amerindian, or Mestiza\nmujer‘s role in the movement. J.T.", "pred_label": "__label__POS", "pred_score_pos": 0.7509477138519287}
{"content": "Abstract\nWe have developed a Ni/ZSM-5 catalyst and utilised it to completely hydrogenate a series of condensed arenes, including naphthalene, anthracene and phenanthrene, under relatively mild conditions. The yields of decalin, perhydroanthracene and perhydrophenanthrene reached 100%, 98.8% and 25.8%, respectively. By analyzing the isomer distribution of the perhydroarenes, we proposed a mechanism of biatomic hydrogen transfer, which was further proven via the hydrogenation of 9,10-diphenylanthracene. Through hydrotreatment over the Ni/ZSM-5 catalyst, both high-temperature coal tar rich in condensed arenes and low-temperature coal tar mixing arenes with alkanes were greatly upgraded. The majority of arenes in the coal tars were deeply and even completely hydrogenated, which may open up a route for further processing and application of coal tar as clean fuels.\nAll Science Journal Classification (ASJC) codes Chemistry(all) Chemical Engineering(all)", "pred_label": "__label__POS", "pred_score_pos": 0.5969694256782532}
{"content": "In light of today’s global economy and variable markets, achieving financial success can be a complex and confusing process for even the most experienced investors, one that requires a significant amount of time, knowledge, and resources. We provide access to the necessary tools, personalized services, and expertise to help you develop a well-coordinated plan that goes beyond one-dimensional product strategies.Smart investing shouldn’t perplex, puzzle, or confound. Our data-driven strategies may help you avoid even the deepest of pitfalls.", "pred_label": "__label__POS", "pred_score_pos": 0.8937187790870667}
{"content": "Reports\nSearch filters applied: community services, universities AND 2011 AND workforce and capability .\nActions for Volume Nine 2011 focus on Education and Communities\nThe report includes comments on financial audits of government agencies in the Education and Communities sectors. The audits of the above entities’ financial statements for the year ended 30 June 2011 resulted in unmodified audit opinions within the Independent Auditor’s Reports. A key finding was that Treasury should consider issuing further guidance to arts and cultural bodies on collection valuation methodologies due to the significance of these asset\nActions for Volume Two 2011 focusing on Universities\nNew South Wales’ ten universities recorded a combined operating surplus of $582 million in 2010, similar to last year’s surplus of $494 million.Capital works expenditure increased by 16 per cent from $874 million in 2009 to $1,015 million in 2010. Despite this, financial and reputational issues continue for universities.", "pred_label": "__label__POS", "pred_score_pos": 0.5934488773345947}
{"content": "by Annamaria Lusardi, Olivia S. Mitchell, Noemi Oggero; CeRP WP N. 173/17\nAbstract\nWe analyze older individuals’ debt and financial vulnerability using data from the Health and Retirement Study (HRS) and the National Financial Capability Study (NFCS). Specifically, in the HRS we examine three different cohorts (individuals age 56–61) in 1992, 2004, and 2010 to evaluate cross-cohort changes in debt over time. We also use two waves of the NFCS (2012 and 2015) to gain additional insights into debt management and older individuals’ capacity to shield themselves against shocks. We show that recent cohorts have taken on more debt and face more financial insecurity, mostly due to having purchased more expensive homes with smaller down payments.\npublished: September 2017", "pred_label": "__label__POS", "pred_score_pos": 0.7227317094802856}
{"content": "2020-07-17 ECHO recognizes climate change as a profound reality faced by small-scale farmers. Many of our publications have focused on helping farmers cope with related challenges such as heat and drought.Increasing farmer resilience and minimizing risk have been key elements of the practices we have...\nECHOcommunity.org is the online collaborative membership community of ECHO, an international nonprofit organization. ECHO exists to reduce hunger and improve lives through agricultural training and resources. Working through regional impact centers around the world ECHO connects small-scale farmers, and those working to eliminate world hunger, with essential resources, and each other. These resources include a vast knowledgebase of practical information, experienced technical support and an extensive seed bank focused on highly beneficial underutilized plants.\nAssociation Management Software Powered by YourMembership.com® :: Legal/Privacy", "pred_label": "__label__POS", "pred_score_pos": 0.9761327505111694}
{"content": "Class IIa HDAC inhibition reduces breast tumours and metastases through anti-tumour macrophages\nNature：抑制IIa类组蛋白去乙酰化酶可诱导抗肿瘤巨噬细胞分化募集从而抑制乳腺癌生长和转移扩散\n10.1038/nature21409\n2017-03-08, Letter\nAbstract & Authors:展开\nAbstract:收起\nAlthough the main focus of immuno-oncology has been manipulating the adaptive immune system, harnessing both the innate and adaptive arms of the immune system might produce superior tumour reduction and elimination. Tumour-associated macrophages often have net pro-tumour effects, but their embedded location and their untapped potential provide impetus to discover strategies to turn them against tumours. Strategies that deplete (anti-CSF-1 antibodies and CSF-1R inhibition) or stimulate (agonistic anti-CD40 or inhibitory anti-CD47 antibodies) tumour-associated macrophages have had some success. We hypothesized that pharmacologic modulation of macrophage phenotype could produce an anti-tumour effect. We previously reported that a first-in-class selective class IIa histone deacetylase (HDAC) inhibitor, TMP195, influenced human monocyte responses to the colony-stimulating factors CSF-1 and CSF-2 in vitro. Here, we utilize a macrophage-dependent autochthonous mouse model of breast cancer to demonstrate that in vivo TMP195 treatment alters the tumour microenvironment and reduces tumour burden and pulmonary metastases by modulating macrophage phenotypes. TMP195 induces the recruitment and differentiation of highly phagocytic and stimulatory macrophages within tumours. Furthermore, combining TMP195 with chemotherapy regimens or T-cell checkpoint blockade in this model significantly enhances the durability of tumour reduction. These data introduce class IIa HDAC inhibition as a means to harness the anti-tumour potential of macrophages to enhance cancer therapy.\nFirst Authors:\nMichael A Nolan,Anthony Letai\nCorrespondence Authors:\nMichael A Nolan,Anthony Letai\nAll Authors:\nJennifer L Guerriero,Alaba Sotayo,Holly E Ponichtera,Jessica A Castrillon,Alexandra L Pourzia,Sara Schad,Shawn F Johnson,Ruben D Carrasco,Suzan Lazo,Roderick T Bronson,Scott P Davis,Mercedes Lobera,Michael A Nolan,Anthony Letai", "pred_label": "__label__POS", "pred_score_pos": 0.83470618724823}
{"content": "A recent study has claimed that the long-term stimulant abuse has more significant effects on brain volume in women than in men. University of Colorado researchers tried to determine how the brains of people previously dependent on stimulants are different from the brains of healthy people. Read: Are women more sensitive to adverse effects of drugs Researcher Jody Tanabe said that during the research while the women previously dependent on stimulants demonstrated widespread brain differences when compared to their healthy control counterparts the men demonstrated no significant brain differences. The women who were former stimulant abusers showed significant loss of", "pred_label": "__label__POS", "pred_score_pos": 0.9280258417129517}
{"content": "ESC provides critical, time-sensitive advice to help our clients manage EHS and operational risks and liabilities during acquisitions, mergers, joint ventures and divestitures, as well as conduct EHS due diligence for project finance including Equator Principle reviews.\nIn a typical industrial transaction, EHS concerns are often the most challenging issues encountered. ESC creates value by enabling our clients to negotiate knowledgeably and effectively on EHS issues.\nTo facilitate this, ESC’s transaction practice is based on two major activities, the preparation of an EHS Assessment report and the provision of advisory services to the buyer or seller on all EHS aspects of the deal to point of completion, when ESC can create value by actively managing any subsequent claims process to point of closure.", "pred_label": "__label__POS", "pred_score_pos": 0.7548102140426636}
{"content": "Uncategorized April 11, 2020 Abortion in the 1970`s\nAbortionin the 1970’s\nInstitutionalAffiliations\nArticleReview\nThearticle “Lonely, tragic, but legally necessary pilgrimages:Transnational Abortion Travel in the 1970s”, by Beth Palmer,discusses how the Calgary Birth Control Association (CBCA) helpedpeople from Canada to cross to the United States for abortion. Thetitle of the articledepictshowlonely the journey was, but people deemed it a necessary pilgrimage.Most importantly, the article describes the complexities that existedregarding abortion during the time. Some of the challenges occurreddue to inequality in gender and financially based matters where theCBCA claimed actually to practice an inverted form of the oldeconomic discrimination. These elements indicate decision-based onwomen’s socio-economic privileges that highlighted the interestingclass-based distribution of resources.\nTheessence of the current study entails understanding thecharacteristics involved in carrying out abortion in the 1970s. Italso seeks to illustrate how feminism acts contributed or hinderedwomen from getting abortions in Canada and the United States. Thedetermination of these factors plays a significant role in thedemonstration of the tensions that reproductive-rights activistsencountered in addressing the needs of individual women against thelong-term objective of changing the laws and improving accessibility.Most importantly the article points out the shortcomings of theCanadian healthcare system as well as the legal modifications in the1969 omnibus bill because women traveled to the United States toacquire abortions. Nevertheless, such facts compel to the fact thatthe reproductive rights are an international issue.\nAnalysisand Contextualization\nThearticle starts by depicting the story of a woman from Alberta whowent through an abortion procedure and later stated that it entailedthe only answer and way. She also indicated that the abortion broughtabout physical and mental relief from a complicated situationregardless of the fact that most people were against it.Additionally, Alberta’s story indicates her support to the abortionprocedure through portraying the advantages that allowed manyCanadian women to acquire freedom. Contrastingly, she depicts theshortcomings in the Canadian healthcare system that occurred as aresult of lack of accessible services that brought about stress tothe women who suffered from unplannedpregnancies(Palmer, 2011). Most importantly, Alberta’s experience highlightsthe fact that the access to abortion services remained a pressingissue for Canadian women especially after the decriminalization ofthe medical procedure. Consequently, the government attempted toalleviate the situation by making therapeutic abortion possible inhospitals based on the Criminal Law Amendment Act of 1968 and 1969.However, most Canadian women opted to travel for many miles in searchof safe medical abortion procedures. These activities brought aboutthe emergence of several informal groups which helped women connectwith physicians in other local communities with the aim of obtainingabortions. One of the local organizations that existed in the 1970sentailed the Calgary Birth Control Association (CBCA). It helpedpeople, mostly women, to cross borders into the United States toaccess abortions. However, these journeys as propagated by activistswere lonely and tragic but brought about pilgrimages that werelegally necessary (Palmer, 2011).\nBesides,the services offered by the groups in helping people cross bordersexemplify the difficulties that existed in the abortion movementduring the time. They also indicate the undercover strategiesemployed by activists in helping women access abortions.Additionally, they suggest the Canadian healthcare system facedsignificant challenges and lacked the ability to realize the needs ofwomen facing unplannedpregnancies(Palmer, 2011). These may be followed closely by the fact thatreproductive rights entail an international issue majorly influencedby geopolitical borders. On the other hand, the evaluation of thesefactors brings about a revelation of the tension that supporters ofreproductive rights encountered in their attempt to address theimmediate needs of pregnant women as well as the long-term objectivesof improving access to abortion (Palmer, 2011).\nThearticle indicates that the accessibility entails one of the majorvital markers of women rights. It utilizes elements included in 1969feminist manifesto to advocate for the fact that abortion should belegalized and made available to allow women to possess control oftheir bodies. The manifesto “Toward a Female Liberation Movement”,by Rosalind Petchesky, highlights the significance of legal,accessible abortion indicating that it makes the challenging aspectof women’s responsibility for pregnancy less total (Frank, 2014).Nevertheless, it points out that the accessibility to abortionservices does not establish reproductive freedom or ensure an equaldistribution of responsibility for reproduction. Most importantly,the author insists that the law on abortion entails a critical pointof view through which the history of women may be shown. The view ofsuch aspects involves the fact that abortion policies locate women’sautonomy in public as well as attending to intimate sexual relations(Frank, 2014).\nThesimilarity in the issue of legalizing abortion in the United Statesoccurred after many poor women died. Most of the women who died fromillegal abortion, 75 percent, entailed those from poor backgrounds,especially the colored ones. These activities brought about a pushfor legalizing abortion influenced by the civil rights as well as theantiwar movements. These activities contributed to New York State aswell as others passing a law that allowed abortion on demand only ifoccurred in a medical facility conducted by a doctor (Frank, 2014).They also attracted women who could afford it as well as feministnetworks which supported the protests through loans, referrals andfought to keeps abortion prices down. Contrastingly, not all womencould afford to go to New York and thus pursued facilities offeringabortion illegally. These activities contributed towards the U.S.Supreme Court ruling that through the end of the first trimester ofpregnancy, only pregnant women and their doctors had the legal rightto make decisions regarding abortions. The court also indicated thatstates could restrict second-trimester abortions in the interest ofthe safety of the mother. However, it was the responsibility of thestates to protect a baby possessing the ability to survive during thethird trimester (Frank, 2014).\nThearticle “Lonely, tragic, but legally necessary pilgrimages”points that due to the legalization of abortion in America, Albertaadopted the initiative to increase the availability of hospitalscarrying out the procedure. For instance, it indicates that duringthe mid-1970s there were about twenty-six hospitals in the provincethat fulfilled the criteria for providing legal abortions. However,they still faced challenges in that more than one-third of the peopleof Alberta could not access hospitals as the rural facilities lackedaccredited equipment (Palmer, 2011). The unavailability of thisequipment emanated from differences in attitudes among hospitalabortion committees and bed shortages. The women who needed abortionservices had to seek help from medical professionals as well associal workers. Nevertheless, these groups lacked the properequipment to curb the shortcomings of the system and were monitoredto ensure that they followed the necessary policies (Palmer, 2011).\nSimilarto the United States, those Canadian women who traveled to Seattle toobtain abortions included upper and upper middle-income classes. TheCBCA group claimed that it effectively practiced an inverted form ofold economic discriminations through referring women with theresources to travel to the United States for an abortion to makein-province hospital space for women facing financial constraints.The decision pointed out a distribution of resources based on classin that it allowed wealthy women to use personal resources to obtainan abortion and leave the local, hospital-based, insured proceduresto those who lacked other options (Palmer, 2011). Nevertheless,protagonists such as Christabelle Sethna claimed that extensivetravel to access abortion was pursued by marginalized womenespecially the poor, racialized and rural females. Contrastingly,historical evidence indicated that in Alberta, the largest part ofwomen traveling to seek abortion procedures entailed wealthy women.These activities facilitated in shaping the CBCA’s politicalactivism through prodding federal legislators to amend the lawsrequiring women to apply for TAC approval. The organization urgedthat Alberta government to address hospital services as well as addedpressure for local and national political change. These were followedclosely by the persuasion of transnational affiliation with theAmericans. These aspects brought about a cross-border relationshipwith the Abortion Referral Service in Seattle where legal abortionswere readily available (Palmer, 2011).\nTheactivities carried out by the CBCA organization attracted otherAmerican groups which recognized the fact that reproductive rightsexceed borders. These American groups sought to help the CBCA throughproviding abortions and challenging the Canadian laws. These occurredthrough collaboration with organizations such as the National Women’sHealth Coalition based in America that contacted the CBCA to requestthem to send a sympathetic physician for free training in the UnitedStates (Hajek, 2014). The activists for such activities welcomed theidea with the hope that it would boost the success in both countries.Similarly, feminist health centers around the United States providedlow-cost abortion services that emphasized the quality of care. Theyalso maintained political involvement in the reproductive rightsmovement. According to research, when the Supreme Court legalizedabortion in 1973 in America, critics such as the antiabortion forcesled by the Catholic Church, initiated mobilization using a variety ofpolitical tactics (Hajek, 2014). These included campaigning, publicrelations, political lobbying, just to mention a few. Theiractivities succeeded in July 1976 when Congress passed the HydeAmendment banning Medicaid funding for abortion unless in cases wherethe mother`s life was endangered. This led to the withdrawal offinancing for unnecessary abortions. These elements brought aboutintensified effects such as harm and discrimination against womenliving in poverty. For instance, in 1977, a woman in Texas died froman illegal abortion conducted in Mexico after the withdrawal offunding from the Medicaid abortions (Hajek, 2014).\nConclusively,these elements indicate that despite legalizing abortion to ensureavailability of the services to all women, there need to be propermeasures aimed at eradicating illegal procedures. The evaluation ofabortion in the 1970s portrays the fact that women faced immensechallenges such as lack of facilities and trained providers,cumbersome legal restrictions, just to mention a few. There existedmixed reactions among the people in Canada who sought abortionprocedures from the United States as it provided quality services.However, the fight for the provision of better services andprotection of women based on the reproduction rights recognized thatunwanted pregnancies were common across all borders (Palmer, 2011).Most importantly, the people of Alberta, especially women requestedthe CBCA organization to continue their services in helping women inneed. Their activities resonated with those of feminists advocatingfor the reproduction rights for all women regardless of theirfinancial and racial status. Additionally, the supporters and clientsof the CBCA organization agreed with their assessment that the crisisof unwanted pregnancy serves as a critical moment in any woman’slife (Palmer, 2011). They propagated that an unwanted pregnancyentails a time when a woman’s aspirations and those of her familyas well as her personal identity and ethics become especially clearto her. When a woman obtains an unwanted pregnancy she bears theburden of deciding the course of her future which may be affectedpositively or adversely. Therefore, the government and other relevantentities should collaborate in seeking out a cross-border abortion asa catalyst to action for many women. In Alberta, these activitieswere coupled with access to information as well as collaborationbetween the United States medical physicians and the Canadianhealthcare system in providing quality abortion services to all women(Palmer, 2011). Nevertheless, these elements occurred after animmense struggle by activists who believed that the Canadiangovernment should implement the activities of the CBCA organizationin providing the appropriate services (Palmer, 2011).\nReferences\nFrank, G.(2014). The Color of the Unborn: Anti-Abortion and Anti-BussingPolitics in Michigan, United States, 1967-1973.\nGender& History,  26(2),351-378. doi:10.1111/1468-0424.12073\nHajek, A.(2014). Defining Female Subjectivities in Italy: motherhood andabortion in the individual and collective memories of the 1970swomen`s movement in Bologna.\nWomen`sHistory Review,  23(4),543-559. doi:10.1080/09612025.2014.894758\nPalmer, B.(2011). ‘Lonely, tragic, but legally necessary pilgrimages’:Transnational Abortion Travel in the 1970s.\nTheCanadian Historical Review,  92(4),637-664. doi:10.1353/can.2011.0059", "pred_label": "__label__POS", "pred_score_pos": 0.5107229948043823}
{"content": "How many times have public health researchers developed highly effective behavioral interventions to improve a population’s health, only to be thwarted by one simple truth: not enough of the population is using them to make a significant impact? Indeed, the real-world impact of many public health interventions proven effective in clinical trials is often limited […]", "pred_label": "__label__POS", "pred_score_pos": 0.6909143924713135}
{"content": "We evaluate the performance and gettering response of n-type ingot silicon material grown by the noncontact crucible method for photovoltaic applications. As-grown lifetimes are >150 μs and relatively homogeneous through the ingot. We apply standard and extended gettering profiles to elucidate gettering response. Effective minority carrier lifetimes are greater than 700 μs and 1.8 ms at an injection condition of 10\n15 cm -3 after standard and extended gettering schemes, respectively, on samples from near the top of an ingot. Unlike the as-grown state, the wafer lifetime distribution in gettered samples is not homogeneous. In wafers from lower parts of the ingot, concentric-swirl patterns of lower lifetime are revealed after gettering. We hypothesize that gettering removes a large percentage of fast-diffusing impurities, while defect striations similar to swirl microdefects found in Czochralski silicon can in some cases continue to limit lifetimes after gettering. These results indicate that, by application of a tailored gettering process, silicon materials grown by the noncontact crucible method can achieve lifetimes that can readily support high-efficiency solar cells, while highlighting areas for further material improvement.", "pred_label": "__label__POS", "pred_score_pos": 0.8297820091247559}
{"content": "#1 – WORKPLACE INSPECTIONS Trace out emergency exits in available light from emergency lighting. Frequently, debris stored in areas surrounding entrance and exit points pose a hazard in low-light conditions. #2 – STORAGE RACKING Storage racking is a combination of steel frames, beams and associated accessories that have been assembled to support materials (including pallets).\nSome requirements for storage racks that are higher than 8 feet (floor to top of highest shelf) or under 8 feet, if loaded/unloaded by mobile equipment:\nEmployer must ensure storage racks are capable of safely supporting weight of items stored, designed and constructed in accordance with good engineering practice, and used in accordance with the specifications and instructions of the manufacturer or professional engineer. Employer must ensure a qualified person conducts regular inspections of the racking for signs of wear, corrosion, damage, fatigue, or missing/incompatible parts, and ensure regular maintenance and repairs are completed in accordance with specifications/instructions of the manufacturer or professional engineer. #3 – PEDESTRIAN/FORKLIFT INTERFACE A key element of warehouse safety is the interaction between mobile equipment and pedestrians. Wherever possible, designate separate, restricted lanes for mobile equipment and pedestrian traffic. Ensure that pedestrian crossings are located in open areas with good visibility. Ensure that mobile equipment is equipped with audible and visual warning devices. Ensure that both operators and pedestrians maintain a high level of situational awareness at all times.", "pred_label": "__label__POS", "pred_score_pos": 0.903331995010376}
{"content": "This activity promotes development and learning by encouraging children to develop vocabulary, language, and creativity in play. Very young children explore objects and toys primarily to discover their properties; as children mature, their play becomes more creative, complex, and symbolic.\nMaterials Needed: Cookie sheet or tray Toy farm figures, such as farm animals, tractors, etc. Dirt or sand Grass or other nontoxic plants Participants: This activity is intended for adult/child interaction. Directions: Place the dirt, sand, and grass on the cookie sheet. Add the toy farm figures. Show your child how to explore the dirt and grass, and play with the animals. Demonstrate animal sounds or show your child how to have the animals pretend to eat or take a drink. Additional Activities We think you'll also enjoy these... GET WORLD AT HOME\nWe're adding new activities each week - get notified when we do!", "pred_label": "__label__POS", "pred_score_pos": 0.8352539539337158}
{"content": "If your dentist in Richardson TX has told you that you have a cavity, you are not alone. Roughly 78 percent of Americans have had at least one cavity before the age of 17. However, while tooth decay is quite common, many do not know how a cavity actually forms. Understanding the development of dental caries is a critical component to help combat tooth decay. As your family dentist near Plano TX, Breckinridge Dental & Orthodontics explains the process of tooth decay.\nHow Does a Cavity Develop?\nThe formation of a cavity is a slow process that gradually progresses overtime. Teeth contain a hard outer layer known as enamel, which is composed of mineral salts and calcium. While mineral salts are found naturally in saliva, they also make the teeth more prone to acidic damage.\nThroughout the day, plaque begins to form on the teeth, which is why it is essential to brush and floss daily to remove the accumulation. However, if plaque is not removed, it begins to eat away at enamel. The demineralization of the enamel is due to acid that forms when plaque is exposed to sugars from foods and drinks we consume. The acid causes enamel to become porous, allowing tiny holes to develop. Over time, these small holes will increase in size to finally form one large hole. Once this occurs, a cavity has formed.\nDuring the early stage of decay, a small white spot will appear on a tooth, which indicates where minerals have been lost. At this point, your family dentist at Breckinridge Dental & Orthodontics can stop the progression of decay with preventive treatments, such as fluoride or dental sealants. However, if the right intervention is not used, the small white spot will eventually continue to weaken, allowing severe decay to develop.\nSymptoms of a Potential Cavity\nIt is estimated approximately 92 percent of adults have a cavity develop on their permanent teeth, with another 26 percent of adults living with untreated tooth decay. In addition, the Centers for Disease Control and Prevention reports 19 percent of children 2 to 19 years of age have untreated cavities. The reason for the high number of untreated dental caries in both adults and children is largely to due poor oral hygiene and not maintaining regular visits to the dentist. Regular dental checkups provide early diagnosis and intervention for cavity treatment. However, even without the aid of a dentist, there are symptoms of a potential cavity.\nDuring early cavity development, dental caries often does not produce symptoms. But, as time progresses, the tooth will become sensitive to temperature changes and sweet foods. If any symptoms are present, it is essential to contact your dentist for treatment.\nYour Dentist in Richardson TX\nAt Breckinridge Dental & Orthodontics, we want to protect your smile from tooth decay. We provide preventive treatments to stop cavities before they start. With regular checkups and cleanings, we perform the necessary interventions to protect the enamel while also detecting cavities during the early stages. With early cavity detection, we will stop the damage to protect the health and integrity of the tooth.", "pred_label": "__label__POS", "pred_score_pos": 0.7561415433883667}
{"content": "Fleeing a situation of physical or psychological violence is considered essential travel, according to the Secretary of State for Equal Opportunity, Sarah Schlitz.\nThe ban on movement on public roads between midnight and 6.00 AM, decided by the Consultative Committee, does not apply in such situations, Ms Schlitz explained in a press release.\nDuring the March lockdown, there was a sharp increase in domestic violence, with three times the number of calls on hotlines, along with a spike in complaints and related police interventions.\nThe most frequent cases had to do with women who had been abused by violent partners, children or teenagers who were the victims of violence or incest, and LGBTQIA+ persons excluded from their family circles, the Secretary of State explained.\n“People who feel unsafe at home and wish to flee their family circles need to know that they can be given a hearing and taken care of by the police,” she said.\n“We need to prevent a drama from occurring because the person did not dare leave home due to the curfew,” Ms. Schlitz added, noting that the ministerial decree instituting the curfew listed this exception.\nShe also announced that she would invite her colleagues in the Council of Ministers to an emergency meeting to come up with a federal plan against domestic violence, and that she would call for an inter-ministerial meeting on women’s rights.", "pred_label": "__label__POS", "pred_score_pos": 0.891303539276123}
{"content": "Featured Publication Enriching Young Lives: How to Unlock Potential in Young People by Mary Kazangarare\nThis book is about enriching young lives. Mary has extensively explored the seven key themes and perspectives highlighted below:\nMindset: The power of the mind Having a purpose and a meaning in life Self-confidence and positive self-esteem Developing a positive attitude The power of the spoken word The significance of gratitude The influence of peers\nIt is not only academic acquaintance that makes a young person fully rounded in life. This book goes beyond a formal learning environment.\nMary has demonstrated these facets, through real case studies and research. Without some extra humanitarian knowledge and etiquette, a young person may struggle to reach their full potential. In this book, Mary explores the importance of taking a humanitarian approach to academic learning.", "pred_label": "__label__POS", "pred_score_pos": 0.8495209813117981}
{"content": "One Study Shows Asthma Associated with Decreased Risk of COVID-19 in Children\nThe question of whether and how asthma and COVID-19 are related has been an ongoing question since the pandemic’s start. According to the American Academy of Asthma, Allergy, and Immunology, “Few data exist to indicate that having asthma is associated with an increased risk of becoming infected with COVID-19 or a more severe course. Recent reassuring data show that having asthma was not associated with an increased risk of hospitalization or even mortality in COVID-19 hospitalized patients.”\nOne recent study published on November 3rd in the journal,\nClinical Infectious Diseases,looked at COVID-19 rates among children and adolescents (<21 years of age) with a SARS-CoV-2-infected close contact. History of provider-diagnosed asthma was less common in SARS-CoV-2-infected children than in uninfected children (6% vs. 17%; p=0.005), leading the authors to conclude that “asthma is associated with a decreased risk.” They stated, “These observations have led to speculation that asthma may lower SARS-CoV-2 susceptibility, or alternatively protect from severe COVID-19, by promoting a Th2‐dominant immune response or through reduced expression of the SARS-CoV-2 receptor (ACE2).” Similar to other studies, the authors found significant racial disparities, noting that Latinx children represented 21% of those individuals tested for SARS-CoV-2 infection but accounted for 59% of SARS-CoV-2-infected patients.", "pred_label": "__label__POS", "pred_score_pos": 0.9706789255142212}
{"content": "Ladder Rank Salary Data Multiple Linear Regression Analysis\nWhen these data are evaluated with the simplest model that includes only demographic variables the result indicate that, compared to their colleagues who are male, women earn salaries that are 11.5% lower, Asian faculty 2.8% lower, and URM faculty 11% lower. However, only 4% of the salary variation is explained by the model (Table 1). As additional explanatory variables are added to the model, salary differences diminish to less than 1% between women, Asian, and URMs when compared to white men; and the percentage of salary variation explained by the model increases to 91%. This indicates that at the campus level, there is little evidence of salary inequity associated with gender and/or ethnicity.\nProgression Analysis\nThe progression data for all General Campus Ladder Rank Faculty, are plotted below. Normative progression is defined in the Progression Matrix.\nProgress Rate Analysis\nThere has been debate on whether rank should be included in predicting salary. In previous studies, rank is generally included in predictive modeling unless there is evidence of bias against one group progressing through the ranks. Cursory t-tests on the rate of progression indicate that there is no significant difference between White men and Asian or URM faculty. However, women do progress at a slightly slower rate than white men. Further multivariate regression analyses were conducted adjusting for experience, discipline, and initial rank. These analyses showed no significant differences between White men and Women, Asian, or URM faculty. This indicates that it is appropriate to include rank in the regression equations predicting salary. Normative progression is defined in the Progression Matrix.\nSchool Level\nAnalyses at the school level yield a range of results. When controlling for experience, department within the school, and rank, salary differences are, for the most part, similar to that of the campus as a whole, but there are some exceptions.\nGeneral Campus Summary\nIn summary, we found no evidence for systemic inequity in salary associated with gender and/or ethnicity among faculty at the campus level. However this study does highlight several areas for further evaluation including understanding factors contributing to low representation of women and minority faculty in the higher ranks and steps. Progression rates through the ranks should also be further examined.", "pred_label": "__label__POS", "pred_score_pos": 0.5660140514373779}
{"content": "This technology brief is the first in a four-part series that explores artificial intelligence (AI) applications within the criminal justice system. This first brief frames AI, defines common AI terms, and offers a mental model for identifying AI use cases within the criminal justice system. While this brief provides examples of how AI might bring significant benefit to the criminal justice system, it also highlights risks that decision makers should consider when developing or deploying AI tools. Additional briefs provide greater consideration of AI in law enforcement, the criminal courts system, and corrections.", "pred_label": "__label__POS", "pred_score_pos": 0.9999493360519409}
{"content": "Abstract\nDuring the initial avascular phase of solid tumour growth, it is the balance between cell proliferation and cell loss that determines whether the tumour colony expands or regresses. Experimentalists have identified two distinct mechanisms that contribute to cell loss. These are apoptosis and nicrosis. cell loss due to apoptosis may be riferred to as programmed-cell-death, occurring,for example, when a cell exceeds its natural lifespan. In contrast, cell loss due to necrosis is induced by changes in the cells microenvironment,occurring, for example, in nutrient-depleted regions of the tumour. In this paper we present a mathematical model that describes the growth of an avascular tumour which compuises a centual core of necrotic cells, surrounded by an outer annulus of puoliferating cells. The model distinguishes between apoptisis and necrosis. Using a combination of numerical and analytical techniques we present results which suggest how the relative importance of apoptisis and necrosis changes as the tumour develops. The implications of these results are discussed briefly.\nKeywords Cell loss Avascular tumour Micronenvironment Apoptosis", "pred_label": "__label__POS", "pred_score_pos": 0.6559231877326965}
{"content": "Abstract\nScholars have documented numerous examples of how liberals and conservatives differ in considering public policy. Recent work in political psychology has sought to understand these differences by detailing the ways in which liberals and conservatives approach political and social issues. In their moral foundations theory, Haidt and Joseph contend the divisions between liberals and conservatives are rooted in different views of morality. They demonstrate that humans consistently rely on five moral foundations. Two of these foundations-harm and fairness-are often labeled the individualizing foundations, as they deal with the role of individuals within social groups; the remaining three foundations-authority, ingroup loyalty, and purity-are the binding foundations as they pertain to the formation and maintenance of group bonds. Graham, Haidt, and Nosek demonstrate that liberals tend to disproportionately value the individualizing foundations, whereas conservatives value all five foundations equally. We extend this line of inquiry by examining whether different types of liberals and conservatives value the moral foundations to varying degrees. Using survey data (n=745), we rely on a mixed-mode latent class analysis and identify six ideological classes that favor unique social and fiscal policy positions. While most of the respondents belonging to these classes self-identify as conservative, they endorse the moral foundations in varying degrees. Since our findings demonstrate considerable heterogeneity with respect to ideology and moral preferences, we conclude by encouraging scholars to consider this heterogeneity in detailing the motivational and psychological foundations of ideological belief.", "pred_label": "__label__POS", "pred_score_pos": 0.6066811084747314}
{"content": "When a company files bankruptcy, secured and unsecured creditors are often caught off-guard and must quickly determine how to react and the likely financial impact. With FDP’s assistance, secured and unsecured creditors will understand their financial position in bankruptcy, out-of-court reorganization, or other liquidation scenarios. FDP validates the strategies and financial forecast developed by the debtor company's financial advisors. In addition, FDP relies upon our restructuring expertise to assess the situation and work with all the parties in the capital structure to arrive at optimal outcomes for all parties involved. FDP has a bench of highly experienced restructuring professionals with proven track records of success in dealing with companies in distress.", "pred_label": "__label__POS", "pred_score_pos": 0.9420724511146545}
{"content": "Real-World Clinical Experience With the IL-17 Receptor A Antagonist Brodalumab February 2020 | Volume 19 | Issue 2 | Original Article | 132 | Copyright © February 2020 Published online January 17, 2020 Miriam S. Bettencourt Bettencourt Skin Center/Advanced Dermatology & Cosmetic Surgery, Henderson, NV; University of Nevada, Las Vegas, NV\nAbstract\nPsoriasis is a chronic, inflammatory, remitting/relapsing autoimmune dermatologic condition that manifests with scaly, erythematous plaques. It has a significantly negative effect on patient quality of life, as well as increasing their risk of numerous comorbid diseases. Patients are typically treated initially with topical steroids, retinoids, and vitamin D derivatives followed by phototherapy and systemic treatments, including oral, subcutaneous or intravenous immunomodulatory drugs, if needed.\nPsoriasis is driven by T-cell activation and associated with the secretion of proinflammatory cytokines and a dysregulated interleukin- 23/T helper 17 (Th-17) inflammatory response. Eleven biologic therapies and 6 biosimilars that target the 3 main immunological pathways— tumor necrosis factor-α (TNF-α), interleukin 23 (IL-23), and IL-17, are approved for the treatment of plaque psoriasis. While most demonstrate similar effectiveness in clinical trials, patient response in real-world settings is varied. Thus, it is important that the clinician understand the mechanism of action of these drugs as well as their safety profile, unique benefits, and limitations. They must also consider the patient’s disease presentation, severity, and comorbid conditions when determining the most appropriate therapy.\nThis article focuses on the IL-17 inhibitors, secukinumab, ixekizumab, and brodalumab, highlighting their unique mechanisms of action and their efficacy and safety in a real-world clinical setting.\nJ Drugs Dermatol. 2020;19(2)132-136 doi:10.36849/JDD.2020.4774 INTRODUCTION\nPsoriasis is a chronic, inflammatory, remitting/relapsing autoimmune dermatological condition characterized by scaly, erythematous plaques. Patients with psoriasis experience a significantly reduced quality of life due to discomfort from the physical symptoms as well as disability and disfigurement. They also have a higher risk of comorbid conditions, including psoriatic arthritis (PsA), cardiovascular disease, inflammatory bowel disease, metabolic syndrome, chronic kidney disease, mood disorders, including depression, and malignancy.\n1 While the etiology of psoriasis is unknown, there have been many recent advances in the understanding of its pathogenesis. We now know that psoriasis is a T-cell mediated disease involving a dysregulated inflammatory response of the interleukin (IL) 23/T-helper (Th)-17 pathway. In this process, IL- 23 is overproduced by dendritic cells and keratinocytes, which stimulates Th17 cells within the dermis to produce and release additional inflammatory cytokines. This, in turn, activates an inflammatory cascade of downstream effector molecules including IL-17A, IL-17F, IL-22, IL-21, and tumor necrosis factor-α (TNF-α), which is responsible for the keratinocyte hyperproliferation that results in the characteristic scaly plaques. 2-4 Studies conducted in mice demonstrate that removing either IL-23 or IL-17 decreases the progression of psoriasis. 5,6 Mice injected with monoclonal antibodies targeting IL-17 blocked, or neutralized, downstream signaling of this cytokine and decreased epidermal hyperplasia. 5 Similarly, genetically modifying mice to not express IL- 23 or IL-17 receptors significantly reduced psoriatic lesion development upon stimulation with the lesion-causing tumor promoter 12-O-tetradecanoylphorbol-13-acetate. 7 This greater understanding of the immune-mediated pathology of the disease has led to the development of monoclonal antibodies and fusion proteins that block specific cytokines or cytokine receptors involved in psoriatic inflammation. Currently available biologics are the TNF-α inhibitors infliximab, adalimumab, certolizumab, and etanercept; the IL-12/13 inhibitor ustekinumab; the IL-17 inhibitors secukinumab and ixekizumab; the IL-17 receptor blocker brodalumab; and the IL-23 inhibitors guselkumab, tildrakizumab, and risankizumabrzaa. 1 Biosimilars to infliximab, adalimumab, and etanercept are also available.", "pred_label": "__label__POS", "pred_score_pos": 0.8162549734115601}
{"content": "BeyondCapital has announced its Rapid Response Capital Program which aims to deploy an allocated amount of USD 500K into portfolio companies who are in need of immediate capital to overcome the current global crisis.\nWhile founders are no strangers to changing market dynamics, the pandemic has put startups in unfamiliar territory, facing significant financial strains. The Rapid Response Program seeks to reduce the impact of uncertain times on portfolio companies and ensure they are given the opportunity for funding that feeds into their crisis management strategies.\nAs a support entity with 39 portfolio companies, BeyondCapital took proactive steps towards an immediate act to develop a seamless program. BeyondCapital leveraged USD 500K from among its programs to be injected into the Rapid Response Program and immediately deployed as fast working capital.\nThe 2-step selection process consisted of an initial application highlighting the companies’ need for the investment. BeyondCapital held a series of virtual meetings to assess and score start-ups against a specific criteria, including their commitment to overcoming the current situation through resilient and adaptive ways.\nToday, 11 portfolio companies were selected to receive investments from the program's allocated amount of USD 500K. Additionally, a second round of applications from portfolio companies will be assessed.\n'We are proud of the entrepreneurial spirit our portfolio companies have brought into this crisis. The team trusts their ability to turn the crisis into an opportunity and their critical role in the Jordanian community’, states Tamer Al-Salah BeyondCapital’s Managing Director.\nThe ongoing crisis has placed the Healthcare sector under a microscope unlike ever before. Learn all about the industry’s funding and investment trends in our 2019 MENA Healthcare Venture Investment Report.", "pred_label": "__label__POS", "pred_score_pos": 0.8928815722465515}
{"content": "NSK-SD (Nattokinase)\n*Promotes healthy fibrinolytic activity for healthy blood flow and cardiovascular function\nNattokinase, a fibrinolytic enyzme isolated from Japanese natto, helps to maintain healthy activity of the bodys natural clotting and fibrinolytic processes. In an animal study conducted by Biotechnology Research Laboratories and JCR Pharmaceuticals of Kobe, Japan, nattokinase promoted healthy blood flow. Furthermore, researchers from JCR Pharmaceuticals, Oklahoma State University and Miyazaki Medical College indicated that nattokinase supports healthy clotting function compared to placebo. In 1995, scientists at the Miyazaki Medical College and Kurashiki University in Japan demonstrated the potential for nattokinase to support blood vessel health in human subjects. This product is contraindicated for individuals with a history of bleeding tendency or with conditions associated with bleeding. Due to potential synergistic effects, concurrent use with anticoagulant and blood pressure medications should be closely supervised by a health professional.\nNSK–SD™ is a highly purified fibrinolytic enzyme that has demonstrated encouraging potential for supporting endogenous fibrinolytic activity and promoting healthy blood flow, circulation, and blood vessel function. Pure Encapsulations NSK– SD™ is standardized to contain a minimum of 20, 000 FU (fibrinolytic units) per gram.\nServings Per Container:60\nTake 1–2 capsules 2 times per day, 12 hours apart, with or between meals.\nServing Size: 1 vegetable capsule Amount Per Servingnattokinase ... 50mg (2000 FU)(soy) other ingredients: hypo-allergenic plant fiber (cellulose), vegetarian capsule (cellulose, water)", "pred_label": "__label__POS", "pred_score_pos": 0.7660861611366272}
{"content": "Abstract:\nReal-time, online measurements of atmospheric organic aerosol (OA) composition are an essential tool for determining the emissions sources and physicochemical processes governing aerosol effects on climate and health. However, the reliance of current techniques on thermal desorption, hard ionization, and/or separated collection/analysis stages introduces significant uncertainties into OA composition measurements, hindering progress towards these goals. To address this gap, we present a novel, field-deployable extractive electrospray ionization time-of-flight mass spectrometer (EESI-TOF), which provides online, near-molecular (i.e., molecular formula) OA measurements at atmospherically relevant concentrations without analyte fragmentation or decomposition. Aerosol particles are continuously sampled into the EESI-TOF, where they intersect a spray of charged droplets generated by a conventional electrospray probe. Soluble components are extracted and then ionized as the droplets are evaporated. The EESI-TOF achieves a linear response to mass, with detection limits on the order of 1 to 10 ngm¯³ in 5 s for typical atmospherically relevant compounds. ... mehrIn contrast to conventional electrospray systems, the EESI-TOF response is not significantly affected by a changing OA matrix for the systems investigated. A slight decrease in sensitivity in response to increasing absolute humidity is observed for some ions. Although the relative sensitivities to a variety of commercially available organic standards vary by more than a factor of 30, the bulk sensitivity to secondary organic aerosol generated from individual precursor gases varies by only a factor of 15. Further, the ratio of compoundby-compound sensitivities between the EESI-TOF and an iodide adduct FIGAERO-I-CIMS varies by only ±50 %, suggesting that EESI-TOF mass spectra indeed reflect the actual distribution of detectable compounds in the particle phase. Successful deployments of the EESI-TOF for laboratory environmental chamber measurements, ground-based ambient sampling, and proof-of-concept measurements aboard a research aircraft highlight the versatility and potential of the EESI-TOF system.", "pred_label": "__label__POS", "pred_score_pos": 0.623681902885437}
{"content": "Autosomal dominant, uncomplicated familial spastic paraplegia (FSP) is a genetically heterogeneous disorder characterized by insidiously progressive lower-extremity spasticity. Recently, a locus on chromosome 14q was shown to be tightly linked with the disorder in one of three families. We performed linkage analysis in a kindred with autosomal dominant uncomplicated FSP. After excluding the chromosome 14q locus, we observed tight linkage of the disorder to a group of markers on chromosome 15q (maximum two-point lod score 9.70; theta = .05). Our results clearly establish the existence of a locus for autosomal dominant FSP in the centromeric region of chromosome 15q. Comparing clinical and genetic features in FSP families linked to chromosome 14q with those linked to chromosome 15q may provide insight into the pathophysiology of this disorder.", "pred_label": "__label__POS", "pred_score_pos": 0.9255819320678711}
{"content": "an intellectually disciplined process of actively and skillfully conceptualizing, applying, analyzing, synthesizing, and/or evaluating information gathered from, or generated by, observation, experience, reflection, reasoning, or communication, as a guide to belief and action. This includes seeing both sides of an issue, being open to new evidence that disconfirms one's ideas, reasoning dispassionately, demanding that claims be backed by evidence, deducing and inferring conclusions from available facts, and solving problems. a detailed plan to deliver a lesson to a particular cohort of students. The plan usually includes, but is not limited to, content standards, learning goals, instructional strategies, learning activities, student groupings, assessments, materials, resources, and technology. a theory that intelligence encompasses a range of functions and abilities (Gardner 1983). By recognizing that intelligence can manifest through abilities or agilities other than those of a cognitive nature, teacher candidates can adapt their teaching styles and learning activities to better engage and motivate learners (i.e., verbal-linguistic, mathematical-logical, musical, visual-spatial, bodily-kinesthetic, interpersonal, intrapersonal, naturalist, and existential learners).", "pred_label": "__label__POS", "pred_score_pos": 0.6732808351516724}
{"content": "25 April\nGlobally, there are now over 2,721,000 total confirmed cases of Covid-19 and more than 191,000 deaths reported.\nThe growing number of asymptomatic cases and the possibility of people remaining positive for the virus even after a recovery, are of international concern, as many countries seek to end the lock-downs and resume economic activity as the spread of the virus declines.\nEcuador has emerged has having one of the worst Covid-19 infection rates in Latin America. Officials in Ecuador reports that the current case count and deaths are still low compared to the reality due to lack of widespread testing.\nAlthough the situation has become alarming in the majority of the world populations, data over the past two weeks suggest encouraging signs in few of the hardest-hit European countries (Spain, Italy, and France) by a drop and thereafter a declining or stabilized trend in the number of new confirmed cases and deaths.\nThe US, the epicenter of the infection, has reported nearly 50,000 deaths and over 880,000 confirmed cases which is nearly one-third of the confirmed cases of Covid-19 globally.\nLizzy Sunny, Practice Head, Epidemiology, GlobalData, Hyderabad", "pred_label": "__label__POS", "pred_score_pos": 0.8294780254364014}
{"content": "An area from north of Winchester Bay to Cape Foulweather was previously closed due to elevated domoic acid levels. Recent crab samples taken from the area indicate these levels have dropped and remain below the alert level.\nThis reopening of the recreational season applies to crab harvested in the ocean and in bays and estuaries, and on beaches, docks, piers, and jetties. Recreational crab harvesting remains closed along the southern Oregon coast from the north jetty of the Coquille River (including the Coquille estuary) to the California border.\nBelow is a guide for what is currently open and closed for both recreational and commercial crab fishermen. Before crabbing, please confirm the status of ODFW/ODA harvest areas relative to concerns about elevated biotoxins at the website below.\nRecreational crabbing – Currently open in the ocean and in all bays and estuaries that are not under the health advisory.\nCommercial ocean crabbing – Delayed in all areas until at least December 16.\nCommercial bay crabbing – Commercial bay crabbing remains closed in all areas due to the delay in the ocean commercial Dungeness crab fishery.\nDespite the commercial closure, crab and shellfish products sold in retail markets and restaurants remain safe for consumers.\nIt is always recommended to eviscerate the crab and discard the “butter” (viscera or guts) prior to cooking. When whole crab are cooked in liquid, domoic acid may leach into the cooking liquid. It is recommended to discard the cooking liquid, and do not use it in other dishes, such as sauces, broths, soups, stews, stocks, roux, dressings, etc. The consumption of crab viscera is not recommended.", "pred_label": "__label__POS", "pred_score_pos": 0.8085896968841553}
{"content": "UK finance confirmed that £1.2 billion was stolen through fraud and scams in 2018. And, in 2017, almost five million people had money stolen from their bank or credit card account, according to The Independent. How does this happen, and what are the signs of bank fraud? If you’ve been involved in bank fraud, either as a perpetrator or victim, these are the standard stages of the bank fraud investigation process and what your next steps should be.\nWhat is Bank Fraud?\nBank fraud is a term applied to any criminal incident where someone targets an individual or a bank by stealing money. When the victim is an individual, the perpetrator typically uses the victim’s credentials such as bank numbers from a stolen/lost card or another source or through identity theft.\nBut, it’s not just individuals who are targeted. Bank fraud cases also involve instances where individuals sell their bank login details to fraudsters who use these accounts for money laundering.\nThere are several other examples of bank fraud cases. Some of these include criminals committing bank fraud by using shop card machines to issue large refunds to their card and fraudsters attempting to hack bank computer systems.\nWhat is the Bank Fraud Investigation Process?\nIn bank fraud cases where individuals are being targeted, banks tend to follow a standard bank fraud investigation process as outlined below. Banks who have, themselves, been targeted are ramping up security measures to prevent breaches and are increasingly investigating large amounts of money deposited into accounts to ensure these sums aren’t linked to fraudulent activity.\nStage 1 – Detecting Bank Fraud\nThe first step in the bank fraud investigation process is to identify fraudulent activity. Tell-tale signs of bank fraud include unfamiliar payments showing up on a victim’s statement, or unexpected dips into their overdraft. These are things that might go noticed in regularly-checked bank accounts and statements, but sometimes such activity can go unnoticed for some time.\nIf the fraud is happening via identity theft, the victim might receive correspondence such as bills or letters from debt collectors. However, banks might also notify victims of fraud if they think there is suspicious activity on the account, such as an unusually large payment. Victims should contact their bank in the first instance either by phoning their fraud helpline or by going into the branch.\nStage 2 – Investigating the Case\nA common question is, ‘how long do fraud investigations last?’. Once notified of fraud, banks take immediate action to ensure your card is protected by pausing or cancelling the bank card in question and issuing a new one if necessary. This is also generally when victims would call Action Fraud to report the incident and get a crime reference number.\nStage 3 – Reimbursing Stolen Funds\nDo banks reimburse stolen money? Generally speaking, banks should refund stolen money to victims in cases of bank fraud. This can take anywhere from a day to a few days, depending on the duration of the investigation. The only time the bank might refuse reimbursement is if they believe you were an accessory to fraudulent activity or were negligent with your bank security. Fraud victims might take the perpetrator to court if they were unable to retrieve the money from their bank.\nWhat is the Purpose of a Fraud Investigation?\nUltimately, the purpose of a fraud investigation is to return stolen money to the victim as quickly as possible and identify the fraudsters. Fraud investigations also increase awareness of bank fraud cases, improve understanding of how criminals engage in fraudulent activity, and shed light on the fraud process.\nIf you are being taken to court for involvement in bank fraud, please contact our team of specialist fraud lawyers. St Pauls Barristers are experienced and highly skilled in fraud law and have a strong history of defending and prosecuting in fraud cases.", "pred_label": "__label__POS", "pred_score_pos": 0.5659546256065369}
{"content": "The Texas Medical Home Initiative (TMHI) was created in 2008 by a group of diverse stakeholders whose shared belief was that all Texans deserve access to high quality, timely, and person-centered primary care. To accomplish this, the group endorsed the newly created patient-centered medical home (PCMH) model of primary care with a vision that every Texan should have a medical home by 2012.\nFrom 2010-2012 the TMHI, with generous support from a number of organizations, planned and executed a 2-year pilot project involving 7 adult primary care practices in the North and East Texas regions. With an intensive coaching model and twice-yearly learning collaboratives, all 7 practices achieved recognition as a medical home by the National Center for Quality Assurance. The pilot project was an important and successful milestone, yet the TMHI recognized that in order to more widely disseminate the PCMH concept and strengthen the primary care infrastructure throughout a state as vast as Texas, a different approach was needed.\nIn 2012, the TMHI began collaboration with Texas Health Institute (THI), which serves as the state’s public health institute and brings years of experience in convening diverse stakeholder groups across the healthcare spectrum with local, state, and national impact. The collaboration produced six successful annual statewide conferences on primary care and the medical home, known as the\n“Texas Primary Care and Health Home Summit.” In 2018, the collaboration between TMHI and THI evolved into the Texas Primary Care Consortium (TPCC), reiterating their shared commitment to achieving systems-wide impact through primary care transformation efforts across Texas. Most notably, the consortium underlines their recognition for the need to expand their focus beyond the annual summit. TPCC continues to host an annual summit, renamed the “Texas Primary Care Consortium Annual Summit” and is in process of producing a concept paper titled “Primary Care and Health System Transformation in Texas: Assessing Needs and Identifying Opportunities.”\nToday, TPCC leadership remains committed to continuing and expanding the work that began in 2008, engaging additional stakeholders, and persistently examining the most effective methods to achieve our mission and improve the health of all Texans.", "pred_label": "__label__POS", "pred_score_pos": 0.7369591593742371}
{"content": "Historically, mines have been powered using fossil fuels, a costly endeavor when you consider the high price of transportation and storage, not to mention the amount of greenhouse gases (GHG) emitted into the atmosphere — a very high cost to the natural environment. Recently, several mine operators have set ambitious targets to significantly reduce emissions, with aspirations of achieving net-zero operations within the next 25 to 30 years. Their strategy: incorporate green technologies for power generation, as well as energy storage capabilities whenever and wherever possible. So, the question remains, how do we get there?\nThe mine of the future will need to generate nearly 100% of its energy requirements – for powering the mine and supplying the vehicle fleet – with emission-free energy. Currently, there are many technologies in development to help us achieve mass electrification in mining. This includes high-efficiency renewable generation, low-cost energy storage for both short duration and longer duration, high-density battery and hydrogen-powered vehicles, combined heat and power generation from solar-enclosed technologies, and small modular nuclear reactors (SMRs).\nOne of the most appealing use cases to date lies in a hybrid microgrid approach. Several mines have started down this path, integrating wind or solar photovoltaic (PV) generation with short-duration lithium-ion batteries. These configurations typically generate 10-25% of a mine’s total electricity needs. In these low penetration microgrids, the microgrid continues to be controlled by the diesel gen-sets with renewables acting as a reduction to the overall mine load, while short-duration lithium-ion batteries are utilized to reduce the variability that stems from renewable generation. The batteries essentially act as an operating reserve and will either generate or store electricity if there is a significant drop or increase in renewable generation, that is until a diesel gen-set can be safely ramped up or down. This approach allows for fewer gen-sets to remain online at any given time, reducing both fuel consumption and operating costs.\nToday, many mining operations are targeting medium renewable penetration, aiming for 40-60% of the total electricity generated from renewable sources. Continually reducing costs and improving the performance of wind and solar PV, as well as innovations to support reliable operations in extreme climates have made these generation sources more attractive. However, in order to achieve medium to high renewable penetration, the dispatch of the diesel gen-sets must be modified. The renewable generator’s contribution to the microgrid is significant and can no longer be treated as a simple reduction in load. Energy storage integration is a must, allowing all diesel gen-sets to be turned off for several hours. During these short periods, the wind or solar PV generation is high enough to cover the mine’s electricity needs. When the gen-sets are off, the energy storage will control the grid, maintaining power quality, and controlling the variability of the renewable generation.\nIn the future, as more aggressive and higher renewable penetration targets are set, aiming for near 100% renewable penetration, a significant shift in operating strategies is required. In this scenario, diesel gen-sets will only be operated during extended periods of low renewable generation. This will require both high- power energy storage to smooth short-duration intermittency and long-duration energy storage to support the supply of renewable generation, shifting it over several hours of the day. Long-duration storage is key to enabling this operating mode and there are many technologies being developed to support this requirement, including flow batteries, zinc batteries, geothermal and thermal storage, compressed gas storage, and hydrogen storage.\nAs mines reach higher renewable penetration, there will be excess power available at virtually no cost. The amount of excess renewable power available depends on both the mine’s location and the technologies adopted, with up to 50% of the total renewable generation available for heat demand and truck charging. Battery-powered trucks are expected to dominate the market for 100 tonnes of production or less. Heavy payload trucks of 300 tonnes and above will be hydrogen-powered and refilled with green hydrogen, mostly produced with excess power from the mine’s renewable generation output. In sunny locations, heat-intensive mining processes will use solar-enclosed technologies to produce both heat and power with a single generation technology. Lithium mines require a large amount of process steam and will benefit the most from solar-enclosed heat and power technologies. This will consequently lead to the decarbonization of the entire lithium mining processes, further accelerating the uptake of lithium-based batteries for renewable integration and electric vehicles.\nAnd finally, SMRs are another highly anticipated technology pathway for remote mining. SMRs can be factory-produced and meet scaleable power demands, giving the mine the flexibility to add modules based on current and future power demand. SMRs can produce megawatt-scale baseload power that can be complemented by other traditional renewable and storage technologies to meet the mine and fleet energy demand. In Canada alone, a dozen companies have pre-licensing engagements with the Canadian Nuclear Safety Commission. Once a successful demonstration is achieved, the mining sector is set to be a primary target for commercialization, due to its high reliance on expensive diesel fuel in remote areas.\nIt’s no secret that off-grid mines are faced with electricity generation challenges, but with all of these technologies in the commercial development pipeline, we have an incredible opportunity to drastically curb climate change impacts in mining. The time is now!", "pred_label": "__label__POS", "pred_score_pos": 0.5378584265708923}
{"content": "Why do we need stanchions barrier system? by: on\nIn a busy city like Melbourne, road accidents can happen at any moment. Unpredictable events occur on regular bases, some leading to vehicle and property damage or pedestrian and driver injuries.\nRecently, an incident happened in front of the Royal Dental Hospital in a busy Lygon Street in Carlton. The famous street known for popular cafes and restaurants is always packed with students, tourists and locals alike. Besides this, it hosts many of the city’s busiest tram lines.\nBeing an action-packed street, incidents where road signs get run into, cars hitting into trams or similar are not a surprise. Stainless steel stanchions which are usually installed around tram stops as a barrier handrail system is one of the solutions that Australian Handrails offers.\nOur stanchions would protect sensitive locations, and prevent possible collisions, as they are a system capable of withstanding significant force. Both drivers and pedestrians would benefit from the installed stanchions, as they would serve as a guidance for the drivers, warning them to slow down in particular areas.", "pred_label": "__label__POS", "pred_score_pos": 0.6411181688308716}
{"content": "UC Berkeley Enabling Low Carbon Communities: The Roles of Smart Planning Tools and Place-Based Solutions Author(s): Jones, Christopher M. Advisor(s): Kammen, Daniel M et al. Abstract\nThe scale of the climate crisis is immense and solutions are urgently needed. This dissertation develops tools to provide highly tailored carbon footprint information and place-based solutions to U.S. households and communities in three complimentary studies. The first study quantifies the greenhouse gas (GHG) savings potential of different U.S. metropolitan areas and household types within locations, developing average household carbon footprint (HCF) profiles for 28 metropolitan areas, 6 household sizes and 12 income brackets. The model includes emissions embodied in transportation, energy, water, waste, food, goods, and services, and further quantifies GHG and financial savings from potential mitigation actions across all locations and household types. The size and composition of carbon footprints vary dramatically between geographic regions (38 to 52 tCO2e) and within regions based on basic demographic characteristics (<20 to >80 tCO2e). Despite these differences, large cash-positive carbon footprint reductions are evident across all household types and locations.\nUsing national household surveys, the second study develops econometric models to estimate HCF for essentially all U.S. zip codes, cities, counties, and metropolitan areas. The results demonstrate consistently lower HCF in urban core cities (~40 tCO2e) and higher carbon footprints in outlying suburbs (~50 tCO2e), with a range from ~25 to >80 tCO2e in the 50 largest metropolitan areas. In contrast to a vast literature demonstrating GHG savings in more dense cities, analysis of all U.S. locations presents a more complex picture. Population density exhibits a weak but positive correlation with HCF until a density threshold is met, after which range, mean, and standard deviation of HCF decline. While population density contributes to relatively low HCF in the central cities of large metropolitan areas, the more extensive suburbanization in these regions contributes to an overall net increase in HCF compared to smaller metropolitan areas. Suburbs alone account for ~50% of total U.S. HCF.\nResults from this quantitative research have informed the development of \"smart\" online carbon management tools that allow users to quickly calculate, compare and manage household carbon footprints, and to visualize average community carbon footprints using high spatial resolution interactive maps. Yet, the potential benefits of such tools are limited to those who find them, and the information may often do little to increase intrinsic motivation to adopt new low carbon technologies and practices. Following lessons from behavioral sciences, a subsequent study engaged ~2,700 residents in eight participating cities to track and reduce household carbon footprints and compete for the title of \"Coolest California City.\" The yearlong pilot project achieved an estimated 14% reduction in electricity consumption, lending evidence that community-scale climate initiatives, enabled by sophisticated information and communication technologies and motivated local program implementers, can help scale up tailored, place-based climate solutions. Together, this research and accompanying tools and programs provide a framework for individuals and communities to prioritize GHG mitigation opportunities and stimulate collective climate action.", "pred_label": "__label__POS", "pred_score_pos": 0.6427241563796997}
{"content": "Abstract\nBackground: The effectiveness of the 2011-2012 seasonal influenza vaccine was evaluated in adult Korean populations with regard to how well it could prevent laboratory-confirmed influenza and influenza-related complications. Materials and Methods: A retrospective case-control and retrospective cohort study was conducted among patients who visited four selected hospitals from September 2011 to May 2012. The analysis included 1,130 laboratory-confirmed influenza patients. For each influenza case, one control patient was chosen at a ratio of 1:1. A control was defined as an age group-matched patient who visited the same hospital with influenza-like illness within 48 hours of symptom onset but for whom laboratory tests were negative for influenza. Age group and visit date were matched between the cases and controls. Vaccine effectiveness (VE) was defined as [100 × (1-odds ratio for influenza in vaccinated versus non-vaccinated persons)]. The patients with laboratory-confirmed influenza were followed for at least one month through reviewing the medical records and conducting a telephone interview. Results: The VE of the 2011-2012 seasonal influenza vaccine was 3.8% [95% confidence interval (CI), -16.5% to 20.6%] for preventing laboratory-confirmed influenza, -16.1% (95% CI, -48.3 to 9.1) for influenza A and 26.2%(95% CI, -2.6 to 46.2) for influenza B. The age-specific adjusted VE was 0.3% (95% CI, -29.4 to 23.1) among participants aged 19 to 49 years, 11.9% (95% CI, -34.3 to 42.2) among those aged 50 to 64 years and -3.9% (-60.1 to 32.5) among those aged ≥65 years. The adjusted VE for preventing any influenza-related complications was -10.7% (95% CI, -41.1% to 42.2%). Conclusions: The 2011-2012 seasonal influenza vaccine was not effective in preventing laboratory-confirmed influenza or influenza-related complications in adult Korean populations.\nASJC Scopus subject areas Biochemistry, Genetics and Molecular Biology(all) Agricultural and Biological Sciences(all) General", "pred_label": "__label__POS", "pred_score_pos": 0.537442684173584}
{"content": "Abstract\nIn this study, 11 doctoral students and I as the course instructor employed a narrative framework to uncover our perceived truths about our experiences as we interacted, studied, pondered, and journeyed through a qualitative research methods course. Data were my chronologically ordered notes documenting my thinking and perceptions about my students and me, and the doctoral students' chronologically ordered email stories to their peers and to me. I analyzed my students' stories using a modified version of a narrative analytic approach. The inquiry illuminated the doctoral students' growth as researchers and highlighted the power of shared stories. Our narratives captured our lives, and illuminated our joys, worries, intentions, and beliefs.", "pred_label": "__label__POS", "pred_score_pos": 0.9979631304740906}
{"content": "Food and forests: understanding agriculture and conservation trade-offs in Ethiopia\nIn Ethiopia, as in many countries in Africa, policymakers need to better understand and manage the major trade-offs — existing and future — between two competing objectives: increasing agricultural production to meet growing domestic food demand and conserving nature. This briefing explores this issue within the national context in Ethiopia, and makes suggestions for the way forward.", "pred_label": "__label__POS", "pred_score_pos": 0.5813658237457275}
{"content": "French, William C. Environmental Ethics Vol. 17/1 (1995), pages 39-57\nArne Naess and Paul Taylor are two of the most forceful proponents of the principle of species equality. Problematically, both, when adjudicating conflict of interest cases, resort to employing explicit or implicit species-ranking arguments. I examine how Lawrence Johnson’s critical, species-ranking approach helpfully avoids the normative inconsistencies of “biospherical egalitarianism.” Many assume species-ranking schemes are rooted in arrogant, ontological claims about human, primate, or mammalian superiority. Species-ranking, I believe, is best viewed as a justified articulation of moral priorities in response to individuals’\nor entities’ relative ranges of vulnerability and need, rooted in their relative ranges of capacities and interests.", "pred_label": "__label__POS", "pred_score_pos": 0.8264690637588501}
{"content": "Saint Gianna Novena\nAll pregnancies are cause for celebration, as we welcome the gift of new life. Yet pregnancy is also a physical, mental, and spiritual challenge for mothers, and can be made more challenging by health, money, or relationship concerns. The unprecedented COVID-19 crisis has compounded struggles for vulnerable pregnant women.\nSt. Gianna Beretta Molla is a powerful patron for pregnant mothers during this pandemic. As a physician, wife, and mother, she knew intimately what it was like to struggle with a challenging medical diagnosis during pregnancy. (To learn more about St. Gianna’s life, click here).\nWe ask St. Gianna’s prayers for all women who are pregnant during this time, especially those who are particularly vulnerable, that they be supported and strengthened by God and their loved ones during this time of crisis.\nLet us pray:\nO Blessed Mother, you received the good news of the incarnation of Christ, your Son, with faith and trust. Grant your protection to all pregnant mothers facing difficulties.\nGuide us as we strive to make our parish communities places of welcome and assistance for mothers in need. Help us become instruments of God’s love and compassion.\nMary, Mother of the Church, graciously help us build a culture of life and a civilization of love, together with all people of good will, to the praise and glory of God, the Creator and lover of life. Amen.\n(Our Father, Hail Mary, and Glory Be)", "pred_label": "__label__POS", "pred_score_pos": 0.6753121614456177}
{"content": "AMOXES: Advanced Electro-Optical Chemical Sensors NATO SPS G5634\nThe need of effective\nportable chemical detectors and deployment of remote sensing platforms is continuously growing either for civil, industrial and security applications, in particular for the detection and diagnosis of CBRN substances. Nanotechnology enables today the development of innovative chemical sensors with enhanced sensing capabilities, improved selectivity and sensitivity, and higher reliability. AMOXES is a Multi-Year Project (MYP) supported by NATO Science for Peace and Security Programme (SPS), which has the main goal to prepare an innovative electro-optical chemical nano-sensor, never tried so far, that combines two different transduction principles on a single device: i) one conventional conductometric MOX sensor and ii) an optical sensor based on Localized Surface Plasmon Resonance (LSPR) effect excited in the MOX nanostructures. Duration: 01/10/2019 - 30/09/2022 Recent Activities 20/11/2020 24/02/2020 13/01/2020 12/12/2019 22/10/2019 03/10/2019 NATO Science for Peace and Security Programme (SPS)\nThe\nNATO Science for Peace and Security Programme (SPS) seeks to enhance cooperation and dialogue between NATO and partner nations through civil science and innovation. The SPS Programme funds activities relevant to NATO‘s strategic objectives which address SPS Key Priorities. SPS offers grants for collaborative research and development projects, workshops, institutes, and training involving scientists and experts from NATO nations and partner countries.\nThe SPS Programme promotes\nsecurity-related practical cooperation based on scientific research, innovation and knowledge exchange within NATO’s wide network of partner countries. It connects scientists, experts and officials from Allied and partner countries to address security challenges, such as cyber defence, counter-terrorism or defence against CBRN agents; to support NATO-led missions and operations; to foster the development of security-related advanced technologies such as sensors and detectors, nanotechnologies, unmanned aerial vehicles (UAVs); and to address human and social aspects of security such as the implementation of United Nations Security Council Resolution 1325 on Women, Peace and Security (UNSCR 1325).\nIn this regard, the SPS Programme greatly benefits from the expertise of other NATO agencies, divisions and delegations, and bodies such as centres of excellence. The Programme provides the Alliance with a unique channel for\nnon-military communication, including in situations or regions where other forms of dialogue are difficult to establish. It enables NATO to become actively involved in such regions, often serving as the first concrete link between NATO and a new partner.\nThe SPS Programme has evolved continuously since its foundation in 1958. To this end, a comprehensive reorientation of the Programme took place in 2013, which gave SPS a renewed focus on larger-scale strategic activities beyond purely scientific cooperation.\nThe current version of Handbook and its annexes are available on the NATO SPS website: www.nato.int/science.", "pred_label": "__label__POS", "pred_score_pos": 0.5725628733634949}
{"content": "By Zach Theiler\nOn Sept. 5, the International Day of Charity, launched in 2012 to honor Mother Teresa, it is time to recognize the importance of charities in alleviating suffering and promoting human security. Globally, charities are essential to achieving the UN Sustainable Development Goals (SDGs), an expansive set of targets meant to rally the private sector, government, and charities behind the most pressing issues of the 21\nst century. The SDGs inform grant makers in measuring the effectiveness of programs, corporations -social responsibility strategies and government foreign assistance priorities. There are signs that a universal framework has been widely adopted across sectors to address the key challenges of our time, and key to the success of achieving the goals is cross-sector collaboration. Unfortunately, national security policy risks undermining that cross-sectoral collaboration and the ability of nonprofit organizations to contribute to the achievement of the SDGs. This deprives the SDG agenda of a core value charities bring to the table: intimate connections to people and communities.\nThroughout many conflict zones the work of nonprofits is crucial in building peace and security, and furthering SDG 16: Peace, Justice, and Strong Institutions. Although George W. Bush once stated that the “money is the lifeblood of terrorism” and launched a “War on Terror.” After 20 years of violent intervention to stop terrorism, the world is no safer than it was in 2001. Today, politicians understand this, and have passed landmark bills such as the Global Fragility Act in 2019 to better address the root causes of terrorism: unattended societal grievances. It is also understood that nonprofit organizations are essential in implementing the Global Fragility Act, attending to all corners of society, educating youth in conflict zones so they don’t fall victim to violent extremism and lead to another generation of violence. Nonprofits have the trust and networks to work effectively in their local communities. It is here where the value of nonprofits is indispensable.\nUnfortunately, the work of peacebuilding organizations is undermined by vague definitions of the prohibition of “material support” to terrorists – which complicates and discourages nonprofit organizations from working in regions with terrorist presence. The problem was highlighted when the Carter Center, a renowned peacebuilding organization founded by President Jimmy Carter, was sued for hosting a conflict resolution meeting that included Hamas, a listed terrorist organization, in Palestine. According to the plaintiff, holding peace talks and encouraging nonviolent conflict resolution while providing “cookies and tea” to listed terrorists, constituted “material support” to terrorists. The absurd lawsuit was promptly dismissed at the request of the Department of Justice, but it does highlight the vulnerable position peacebuilding organizations working to bridge peace in conflict zones find themselves in.\nIt is essential that nonprofits are able to conduct their activities in the arena of peacebuilding. Governments often do not have the neutral reputation, knowledge of local customs and culture, or trust and connection to local people to understand the societal grievances deeply. This is why national security policy needs to support, not hinder the work of nonprofit organizations. The material support law needs to be updated, and have peacebuilding and humanitarian safeguards to ensure that nonprofits can operate in conflict zones to educate, and empower local communities to bring an end to violence. Only after peace is sustained will we collectively be able to address the other SDGs regarding socio-economic equality and environmental sustainability.\nThe SDGs are largely interconnected. A healthier society is a more productive society, there is a vital connection between public health and strong economies. However, the influence of SDG 16 on all other SDGs cannot be overstated. War cripples economic development. It destroys infrastructure. It makes populations more vulnerable to disease. And it requires the absolute attention of governments, taking time and resources away from important activities like environmental sustainability. Without peace, progress in the SDG agenda will be hamstrung, and without empowering and partnering effectively with nonprofit organizations, we hinder our ability to build peace, engage all corners of society, address the root causes of conflict.", "pred_label": "__label__POS", "pred_score_pos": 0.5652132630348206}
{"content": "In the 3rd session, we will harness the pipeline concept towards manageable high throughput experimentation in ML/DL research.\nCurrently, complex pipelines are found in the field of ML in implementations of automated training and deployment of ML models. However, these pipelines and the code they encapsulate are rarely those that are used in the research stage. Moreover, existing research pipelines tend to be focused on the data preparation stage, and are mostly trivial afterward.\nThis represents several areas where we can do better:\n* Easily “grow” automated multi-stage workflows from research code with minimal code changes. * Frictionless executions of these pipelines on available resources. * Minimizing re-writes when promoting code from research towards “production”\nI will address suggestions for improvements in these, with specific examples from simple to intricate workflows in research.\nIn the previous webinar, we established how ensuring reproducibility in ML research enables automation, which in turn unlocks advanced MLOps (such as pipelines). Since these topics will be used for this webinar, it is recommended to refresh your memory with the recorded event.\nAll sessions of the series:", "pred_label": "__label__POS", "pred_score_pos": 0.9679794907569885}
{"content": "What is\nBYOT Bring your own technology (BYOT) is a policy that permits students or employees to use their digital devices at school or work. To increase technology availability in the higher ed classroom, students are encouraged to bring in cell phones, laptops and tablets to complete instructional activities. In-class technology use can better prepare students for their careers, which will likely require electronic access to applications, data and email. Bring your own technology (BYOT) often refers to the “consumerization of IT:” the expectation of integrating personal devices into the classroom rather than depending on technology chosen by a school or instructor. Students in higher education use their own devices to collaborate with their peers—for example, Google Docs is a popular collaborative tool used for group work—while students can learn from others globally. BYOT is also used interchangeably with Bring Your Own Device (BYOD).", "pred_label": "__label__POS", "pred_score_pos": 0.9361613392829895}
{"content": "did you know...\n1 in 3 American families reports experiencing diaper need.\n5 million children the U.S. aged three or younger live in poor or low-income families.\nInfants require up to 12 diapers per day, toddlers about 8.\nDisposable diapers can cost $70 to $80 per month per baby.\nNo state or federal child safety-net program allocates dollars specifically for the purchase of diapers.\nWithout transportation, buying diapers at a convenience store rather than a large \"big box\" store can significantly increase the monthly cost of diapers.\nMost childcare centers, even free and subsidized facilities require parents to supply a day's supply of disposable diapers.\nThe poorest 20% of U.S. families spend 14% of after-tax income on diapers.\nHelp us provide diapers for children in need by clicking the below button", "pred_label": "__label__POS", "pred_score_pos": 0.9644048810005188}
{"content": "The Tier 2 sponsorship scheme enables employers to sponsor skilled workers from overseas to come to the UK and take roles that cannot be filled from within the resident labour market. It also enables international companies to transfer key personnel into the UK as intra- company transferees.\nOver recent years, UK Government policy has introduced many constraints on the scheme as part of a drive to reduce net migration into the country. Routes to permanent residence have been taken away and an overarching quota has been applied to sponsorship under Tier 2 (General).\nEmployers rely on Magrath Sheldrick to work though a complex minefield of regulations, reducing compliance risk and maintaining a satisfied workforce.", "pred_label": "__label__POS", "pred_score_pos": 0.9605387449264526}
{"content": "Integrated care is characterized by a proactive and person-centered approach to care, which is seamlessly coordinated across multiple professional disciplines and care interfaces. Integrated care aims to improve outcomes such as functioning, quality of life, and quality of care. The organisation of integrated primary and community care is considered an essential step towards supporting older people to age in place.\nMaintaining people’s safety at home\nTo support older people living at home, it is essential to maintain their safety. Older people encounter limitations in multiple domains of life, which could pose risks to their ability to live safely and independently at home. Such risks may relate to different factors, including people’s functioning and behavior, their physical and social environments, and the health and social care they receive. This wide range of risks could lead to a multitude of problems that challenge people’s safety at home, ultimately resulting in emergency department visits, (re)hospitalization, institutionalization and mortality. Given its proactive, interdisciplinary and comprehensive character, integrated care is expected to provide opportunities to address the prevention of such risks.\nOur recently published scoping review in\nBMC Geriatrics shows that integrated care programs for older people living at home address a broad range of safety risks. After examining included programs according to the predefined conceptual framework shown in Figure 1, findings show that all programs addressed risks related to people’s functioning and behavior, and several programs addressed risks associated with people’s health and social care management. Fewer programs addressed risks related to people’s social and physical environments. However, as the number of people receiving care and support at home keeps rising, risks related to people’s socio-economic conditions, their home environments, and increasing caregiver responsibilities, for example, are becoming more prominent. Therefore, addressing such risks is important, especially since older people themselves also express their concerns regarding these issues.\nTimely identification of risks, combined with relevant clinical, behavioral and environmental interventions and support, as well as care coordination or case management, would enhance care providers’ ability to support older people’s safety at home. Prioritizing such a proactive and multidimensional approach requires combining the expertise of professionals from different disciplines of health and social care. However, our scoping review suggests that these linkages between health and social care are not yet common practice in integrated care programs for older people living at home. Investing in collaborative skills and inter-professional dynamics, as well as addressing financial and organisational incentives for collaboration, are deemed necessary to strengthen these linkages.\nBalancing safety, autonomy, quality of care and quality of life\nThis review showed that integrated care programs can potentially incorporate many ways of addressing and preventing risks. However, it remains challenging to priorities these activities in a way that is meaningful for older people. Adopting a person-centered way of working, in which professional expertise is tailored to people’s individual needs and preferences, is considered one of the core components of integrated care. In this light, it is important to acknowledge that safety is not the only aspect to consider, especially in the care provided in the context of people’s homes. People’s homes are not only care settings, but the setting of their daily lives, and older people may have preferences or make choices that value quality of life over safety. This means that safety risks cannot be addressed independently of older people’s perspectives. Instead, professionals are tasked to consider their professional perceptions in combination with older people’s preferences, and find a balance between aspects such as safety, prevention, autonomy and quality of life.\nTruly supporting people to age in place requires a societal shift towards a broader paradigm of health and well-being.\nHowever, in practice, this raises the question of responsibility and accountability for the safety of older people living at home. Naturally, professionals have no control over how older people live their lives and the choices they make. As such, professionals cannot be held accountable for the adverse consequences of those choices. What then, exactly, is the responsibility of health and social care professionals? And what is the responsibility of older people themselves, their families, or society? How is accountability for adverse events shared across these different stakeholders? These questions necessitate a widespread debate on our perceptions and expectations of quality of care, prevention, and ethics, as well as individual, professional and societal responsibility and accountability.\nExpanding the health care paradigm\nConcluding, integrated care provides both a platform and tools that could be harnessed further to support older people living at home in a manner that balances safety with other values important to older people. However, it is important to note that efforts to integrate health and social care alone are not enough. Truly supporting people to age in place requires a societal shift towards a broader paradigm of health and well-being – a paradigm that recognizes the role that health, social, and environmental factors play in older people’s ability to live safely at home, and in which many different actors in the wider community play their part and perform their responsibilities.", "pred_label": "__label__POS", "pred_score_pos": 0.6265390515327454}
{"content": "Proc. Natl. Acad. Sci., 117 (28), 16174-16180 (2020).\nDOI: 10.1073/pnas.2000606117\nUrban mining of precious metals from electronic waste, such as printed circuit boards (PCB), is not yet feasible because of the lengthy isolation process, health risks, and environmental impact. Although porous polymers are particularly effective toward the capture of metal contaminants, those with porphyrin linkers have not yet been considered for precious metal recovery, despite their potential. Here, we report a porous porphyrin polymer that captures precious metals quantitatively from PCB leachate even in the presence of 63 elements from the Periodic Table. The nanoporous polymer is synthesized in two steps from widely available monomers without the need for costly catalysts and can be scaled up without loss of activity. Through a reductive capture mechanism, gold is recovered with 10 times the theoretical limit, reaching a record 1.62 g/g. With 99% uptake taking place in the first 30 min, the metal adsorbed to the porous polymer can be desorbed rapidly and reused for repetitive batches. Density functional theory (DFT) calculations indicate that energetically favorable multinuclear-Au binding enhances adsorption as clusters, leading to rapid capture, while Pt capture remains predominantly at single porphyrin sites.", "pred_label": "__label__POS", "pred_score_pos": 0.9967231154441833}
{"content": "Abstract\nDespite recent advances in our understanding of the mechanisms underlying systemic inflammatory response syndrome (SIRS) and sepsis, the current therapeutic approach to these critically ill patients is centered around supportive care including fluid resuscitation, vasopressors and source control. The incidence of SIRS and sepsis continues to increase in the United States and patients die due to failure to respond to the traditional therapies of nitric oxide blockade, adrenergic agonists, etc. Bacterial and mitochondrial N-formyl peptides (NFPs) act as damage-associated molecular patterns and activate the innate immune system through formyl peptide receptors (FPR) located in immune and non-immune cells, including the vascular endothelium. The resulting inflammatory response manifests as capillary leak, tissue hypoperfusion and vasoplegia, partially due to endothelium barrier breakdown. Potential strategies to prevent this response include decreasing NFP release, breakdown of NFPs, and blocking NFPs from binding FPR. We propose the use of deformylase, the degrading enzyme for NFPs, as potential therapeutic approach to prevent the deleterious effects of NFPs in SIRS and sepsis.\nKeywords DAMPs Deformylase Endothelium Formyl peptide receptor-1 SIRS Sepsis Trauma ASJC Scopus subject areas Immunology and Allergy Immunology", "pred_label": "__label__POS", "pred_score_pos": 0.6860203742980957}
{"content": "Swinth, Kirsten, Feminism's Forgotten Fight: The Unfinished Struggle for Work and Family. Cambridge: Harvard University Press, 2018. 339 pages. Hardcover, $35.00\nIn Feminism's Forgotten Fight: The Unfinished Struggle for Work and Family, historian Kirsten Swinth explores the illusion of women having it all by engaging the persistent struggle that continues for social, economic, and political change. Swinth examines the second wave of feminism, the progress made toward women's equality and the challenges that still persist, including a lack of equality for non-white women and women in poverty. The focus of the text highlights the journey of women seeking to attain a healthy balance between home and work. Additionally, the author notes that the \"motherhood penalty\" does truly exist, as women pursuing this illusive balance have greater stress and lower wages (251).\nSwinth explains that the second wave of the feminist movement reconstructed the way individuals see personal, family, social and economic identities, but failed to sustain progress for women to achieve the totality of their aspirations. Such movements afforded women the right to work and earn wages but did not fully address core issues such as childcare, housework, and inequality among groups of females of color, immigrant status, and those in poverty. The concept of care work is discussed thoroughly in chapter five, highlighting the inequality of the value of women's work, which remains a pertinent issue in addressing the wage gap and unequal pay today. Gender studies enthusiasts would benefit from this work, as it provides a comprehensive and historical perspective of feminism's victories and unfulfilled promises. Swinth's discussion of advancements made by the feminist movement, and the areas that still require further critical analysis, encourage readers to think more about what...", "pred_label": "__label__POS", "pred_score_pos": 0.9997488856315613}
{"content": "Abstract\nThe electrode ionomer is a key factor that significantly affects the catalyst layer morphology and fuel cell performance. Herein, sulfonated poly(arylene ether sulfone)-based electrode ionomers with polymers of various molecular weights and alcohol/water mixtures were prepared, and those comprising the alcohol/water mixture showed a higher performance than the ones prepared using higher boiling solvents, such as dimethylacetamide; this is owing to the formation of the uniformly dispersed ionomer catalyst layer. The relation between ionomer molecular weight for the same polymer structure and the sulfonation degree was investigated. Because the chain length of polymer varies with molecular weight and chain entanglement degree, its molecular weight affects the electrode morphology. As the ionomer covered the catalyst, the agglomerates formed were of different morphologies according to their molecular weight, which could be deduced indirectly through dynamic light scattering and scanning electron microscopy. Additionally, the fuel cell performance was confirmed in the current-voltage curve.\nKeywords Hydrocarbon-based electrode ionomer Membrane-electrode assembly Polymer electrolyte Proton exchange membrane fuel cell Sulfonated poly(arylene ether sulfone) ASJC Scopus subject areas Renewable Energy, Sustainability and the Environment Fuel Technology Condensed Matter Physics Energy Engineering and Power Technology", "pred_label": "__label__POS", "pred_score_pos": 0.8736389875411987}
{"content": "While mortgage lenders use lending ratios, such as the percentage of a borrower's debt to their income, in deciding whether to approve a loan, a borrower's household budget may determine how much they want to spend each month on housing. That monthly payment will determine how large a loan the borrower can expect to receive based on the term of the loan, down payment and interest rate. Other monthly expenses such as insurance, taxes, and HOA dues will also factor into the calculation.", "pred_label": "__label__POS", "pred_score_pos": 0.7908245325088501}
{"content": "Important Nutrients\nFat and carbohydrates\nDogs use fat as their primary energy source. An overweight dog stores fat more easily if the calories are consumed in the form of fat than if they are from carbohydrates. An overweight or obese dog should be fed a low-fat, high-carbohydrate diet to restrict calories available from fat, which is important for dog weight control.\nFiber and fatty acids\nA normal fiber level, provided in a moderately fermentable fiber source, helps create and maintain healthy digestion. This is especially important for the dog on a diet. Some weight-loss foods for dogs dilute calories with high levels of fiber. High-fiber foods may reduce the digestibility and absorption of many nutrients, including fat. These foods reduce weight by providing what would be considered poor-quality nutrition. These high-fiber diets also result in large, frequent stools and decreased skin and coat condition. Dog foods such as IAMS™ ProActive Health™ Adult Weight Control, which provide essential fatty acids like those found in vitamin-rich fish oils, help maintain your dog's healthy skin and coat despite lowered fat levels.\nGradual Weight Loss\nThe goal of a good weight management program should be gradual weight loss. Dogs should lose 1% to 2% of their initial weight per week. This can be achieved by reducing the caloric intake by 30% to 50% of maintenance.\nA total weight management program can lead to successful weight loss in the obese dog. Before beginning any weight-loss program with your dog, discuss it with your veterinarian. Remember, your support is essential to your dog's weight-control success.", "pred_label": "__label__POS", "pred_score_pos": 0.6478016972541809}
{"content": "We believe the Holy Spirit is God. He is explicitly affirmed to be God (Acts 5:3-5). He displays divine attributes such as omnipresence (Psalms 139:7-8), omniscience (1 Corinthians 2:10-11), omnipotence (Luke 1:35), and eternality (Hebrews 9:14).\nHe performs divine works such as creation (Gen. 1:2; Psalms 104:30; Job 26:13; 33:4), inspiration of the scriptures (2 Peter 1:20-21), and regeneration (John 3:3-8; Titus 3:5). He is co-equal and co-eternal with the Father and the Son (Matthew 28:19-20; 2 Corinthians 13:14; Ephesians 2:18).\nWe believe the Holy Spirit is a person. He is specifically referred to, with personal designation, as the Comforter (John 15:26). Personal pronouns are used of Him (Acts 10:19-20). The Greek word pneuma (Spirit) is a neuter gender word. Any pronoun used to substitute for pneuma would normally also be neuter. However, while under the inspiration of the Spirit, the Biblical writers did not follow this grammatical pattern; instead, they substituted masculine pronouns to designate the Holy Spirit (John 15:26; 16:13-14). He displays the following characteristics of a personality: intelligence (Romans 8:27), emotion (Eph. 4:30), and will (1 Corinthians 12:11). He personally relates to mankind in these ways: He can be lied to (Acts 5:3-4), blasphemed (Matt. 12:31), insulted (Hebrew 10:29), resisted (Acts 7:51), grieved (Ephesians 4:30), and obeyed (Acts 10).\nWe believe the Holy Spirit was active in Old Testament times. He was involved in creation (Genesis 1:2). He inspired the writing of the Old Testament (2 Peter 1:20-21; Acts 1:16; Hebrews 3:7). He empowered people for specific tasks, such as leadership (Jude 3:10; 6:34, 1 Samuel 11:6) and prophecy (Numbers 24:2). All through the Old Testament, people were influenced by the Holy Spirit (Genesis 6:3; Nehemiah 9:20).\nWe believe the Holy Spirit’s ministry extends to unbelievers as well as believers. The Spirit convicts the world (unbelievers) of sin, righteousness, and judgment (John 16:8-11). It is His power that brings the sinner under conviction of sin and draws the sinner to Christ for salvation (John 16:8-11). It is through the Spirit that men are regenerated (John 3:5-6). By the Holy Spirit, Jesus Christ baptizes believers into His body (the church – 1 Corinthians 12:13) and into Himself (Romans 6:1-10).\nAll of the children of God are permanently indwelled with the Spirit (John 14:16-17; Romans 8:9; Ephesians 4:30). The Spirit not only seals believers, but He is the down payment or the pledge of the inheritance to come (Ephesians 1:14; 4:30; 1 Corinthians 6:19; 2 Corinthians 1:22). The believer continues to experience the benefits of the Holy Spirit’s ministry throughout his Christian life. The Holy Spirit intercedes (Romans 8:26-27), teaches (1 Corinthians 2:10-13; 1 John 2:20,27), illuminates (Ephesians 1:17-18), empowers (Zechariah 4:6; Romans 15:19; Ephesians 3:7), guides (John 16:13),and sanctifies (1 Thess. 5:23 2; 2 Corinthians 3:14). Believers are commanded to be filled (controlled) with the Spirit (Ephesians 5:18). When the Spirit is in control of the believer, He will produce holiness (Galatians 5:16) and fruitfulness (Galatians 5:22-23) through the believer. The Spirit-filled life is the Spirit filling the believer with the life of Christ (Galatians 2:20). The Spirit-filled life is the only way to live victoriously (John 6:63). The baptism of the Spirit is experienced by all believers, it occurs at the moment of salvation, and it is not to be repeated (Mark 1:8; 1 Corinthians 12:13). It is a result of placing one’s faith in Jesus Christ (John 3:5-6, 16). The filling of the Holy Spirit is a command to all believers to be continually under the control or influence of the Spirit. We believe the Holy Spirit distributes gifts to every believer according to His will (1 Corinthians 12:11) as a stewardship for believers to serve others (1 Peter 4:10), for the edification of the church (Ephesians 4:16), and the glory of God (1 Peter 4:11).", "pred_label": "__label__POS", "pred_score_pos": 0.7511590123176575}
{"content": "Beta-Hydroxybutyrate Enhances BDNF Expression by Increasing H3K4me3 and Decreasing H2AK119ub in Hippocampal Neurons\nNeurological evidence suggests that beta-hydroxybutyrate (BHBA) has positive effects on the central nervous system. Previous studies have explored the molecular mechanisms by which BHBA affects different brain functions, but the effects of BHBA on epigenetic modifications remain elusive. Here, we showed that BHBA enhanced brain-derived neurotrophic factor (BDNF) expression by increasing H3K4me3 and decreasing H2AK119ub occupancy at the Bdnf promoters I, II, IV, and VI in hippocampal neurons. Moreover, BHBA treatment induced the upregulation of H3K4me3 and downregulation of H2AK119ub on the global level, both of which were dependent on the L-type calcium channel. Additionally, the BHBA-activated L-type calcium channel subsequently triggered the activation of Ca\n2+/CaMKII/CREB signaling, and promoted the binding of p-CREB and CBP to Bdnf promoters. These results indicate that BHBA regulates cellular signaling and multiple histone modifications to cooperatively modulate BDNF, suggesting a wide range of regulatory effects of BHBA in the central nervous system.", "pred_label": "__label__POS", "pred_score_pos": 0.9828692078590393}
{"content": "Objectives: This study investigated the effects of multiple prompts, telephone calls, and written reminders on attendance at group support meetings in a long-term residential facility for survivors of domestic violence. Methods: Participants were 15 Hispanic women who were residing in the facility at the time of the study. Prompts to attend the support meetings were introduced, removed, and reintroduced within an ABAB single-system design. Results: Data from sign-in sheets showed that prompting procedures at least doubled attendance at the support meetings. Conclusions: Possible factors contributing to the effectiveness of social workers using prompts to promote attendance at group support meetings are briefly discussed. (Author Abstract)", "pred_label": "__label__POS", "pred_score_pos": 0.9508771896362305}
{"content": "Abstract\nAccurate estimates of both above-ground biomass (AGB) and below-ground biomass (BGB) are essential for estimating carbon (C) balances at various geographical scales and formulating effective climate change mitigation programs. However, estimating BGB is challenging, particularly for forest ecosystems, so robust allometric equations are needed. To obtain such equations for savanna-woodlands of the West African north sudanian zone, we selected four common native woody species (Anogeissus leiocarpa (DC.) Guill. & Perr., Detarium microcarpum Guill. & Perr., Piliostigma thonningii (Schumach.) Milne-Redh. and Vitellaria paradoxa C. F. Gaertn.). At two sites in Burkina Faso, we determined the BGB of 30 trees of each of these species by excavation, and measured various above-ground dimensional variables. The root: shoot ratio varied widely among the species, from 0.1 to 3.4. Depending on the species, allometric equations based on stem basal area at 20 cm height, basal area at breast height and tree height explained 50-95% of the variation in BGB. The best generic equation we obtained, based on basal area at 20 cm, explained 60% of the variation in BGB across the species. Three previously published generic allometric equations underestimated BGB by 8 to 63%. The presented equations should significantly improve the accuracy of BGB estimates in savanna-woodlands and help avoid costly needs to excavate root systems.\nFields of Science 4112 Forestry", "pred_label": "__label__POS", "pred_score_pos": 0.962199330329895}
{"content": "Antibiotic resistance is one of the greatest health challenges of the modern day. It's especially prevalent, and must be acted on, in Australia's remote Indigenous communities.\nToxic shock syndrome is the body's response to toxins produced when bacteria that lives in and on us grows to dangerous levels.\nA team of medievalists and scientists look back to history – including a 1,000-year-old eyesalve recipe – for clues to new antibiotics.\nWhich of the following conditions would you prefer to have during your next stay in hospital? A. Staphylococcus aureus (Golden Staph) bloodstream infection; or B. a heart attack?", "pred_label": "__label__POS", "pred_score_pos": 0.7094833850860596}
{"content": "摘要\nObjective: Renin-angiotensin-aldosterone system blockers are the preferred antihypertensive medications in patients with diabetes and prior stroke. This study aimed to compare the effects of angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin II receptor blockers (ARBs) in terms of major adverse cardiac events (MACEs) in patients with diabetes who survived ischemic stroke. Methods: We conducted an observational, nationwide, propensity score-matched cohort study using Taiwan's National Health Insurance Research Database. Patients aged at least 20 years with type 2 diabetes who initiated ACEI (n=15 959) or ARB (n=23 929) use within 90 days after discharge for first ischemic stroke between January 2000 and December 2011 were allocated to ACEI and ARB groups, respectively. The primary outcomes were MACEs (myocardial infarction, ischemic stroke, and cardiovascular mortality). The secondary outcomes were hospitalization for acute kidney injury and hyperkalemia. Intention-to-treat and as-treated models were used. Results: Intention-to-treat analysis showed no significant difference between the ACEI and ARB groups in the outcomes of MACEs [hazard ratio (HR), 0.99; 95% confidence interval (CI), 0.95-1.04], including ischemic stroke (HR, 1.01; 95% CI, 0.97-1.06), myocardial infarction (HR, 1.06; 95% CI, 0.95-1.18), and cardiovascular mortality (HR, 0.98; 95% CI, 0.91-1.06). As-treated analysis produced similar results. Additionally, the groups showed no difference in the risk of hospitalization for acute kidney injury or hyperkalemia. Conclusion: Our study supports the hypothesis that the risks of MACEs and two additional secondary outcomes in patients with diabetes who survived ischemic stroke did not differ according to ACEI versus ARB use.\nASJC Scopus subject areas Internal Medicine Physiology Cardiology and Cardiovascular Medicine", "pred_label": "__label__POS", "pred_score_pos": 0.8343510031700134}
{"content": "Despite locust outbreak, grain production in most acutely affected African countries set to be highest on record\nSeveral countries in the “Horn” region of Africa are facing the brunt of what the U.N. Food and Agricultural Organization (FAO) describes as the “worst desert locust crisis in 25 years.” Paradoxically, grain production in those countries is forecast to hit record volumes. The current desert locust outbreak originated in mid-2018 when successive rain events in the arid Arabian Desert spurred vegetation development. The latter, in turn, provided ample feedstock for the burgeoning locust population. Trade winds blew the pests into Africa in early 2019, where the locusts settled into the low-elevation arid to semi-arid grasslands. Regionally abundant rainfall through the end of 2019 and into 2020 supported vegetation growth, which once again aided in the expansion of locust swarms. However, the locusts primarily remained in low-elevation grasslands, largely avoiding the higher-elevation grain production zones. Further, the rainfall that increased feedstock for the locusts also helped increase yields for agricultural crops, such as corn, barley, sorghum, and wheat. Ultimately—and despite a significant locust infestation—grain production in this region is forecast not only above the 2019 levels but also to reach the highest level on record. This situation mirrors that of the less severe locust infestation of 2003-05, during which aggregate grain production rose during the height of the outbreak. This chart is drawn from material included in the Economic Research Service’s\nWheat and Feed Outlook reports from August 2020, and has been updated with November data.\nDownload higher resolution chart (2084 pixels by 2015, 300 dpi)", "pred_label": "__label__POS", "pred_score_pos": 0.9788064956665039}
{"content": "Our priority is to help you maintain your independence as you age. We offer home-based visits, personal evaluations and yearly cognitive assessments.\nSpotlight Among the Best in the U.S. for Geriatrics Services U.S. News and World Report ranked Rush University Medical Center as a high performing hospital in geriatrics services. The Rush Approach to Geriatrics Services\nAs your body ages, it changes. Our geriatricians specialize in helping seniors navigate these changes by providing personalized primary care for adults over the age of 65.\nGeriatricians are your partners in helping you manage the complex and often interrelated health conditions, such as Alzheimer's disease or Parkinson's disease that can come with aging.\nRush Excellence in Geriatrics Services Personalized evaluations:Your geriatrician may conduct a geriatric assessment, a thorough evaluation of your physical and mental health and abilities. This assessment includes evaluation of your nutrition, hearing, vision, and any issues with incontinence, balance or memory. For example, if we learn you have a diet that's high in salt, we might encourage you to cut back on the fatty meats and switch to fish. Or if we find out you need a caregiver at home, we'll help connect you with one. We do annual cognitive assessments:Whether it's your vision or memory, you might not recognize age-related changes. That's why each year, we'll do a cognitive assessment to note any changes. Annual cognitive assessments are important because it gives us the chance to make an early diagnosis, helps you plan for future treatment and decreases any anxiety you might have about aging. We're your team:Geriatricians collaborate with other providers at Rush as needed to treat conditions associated with aging, such as Alzheimer's disease or functional decline. They also work closely with palliative care providers who offer an extra layer of support and focus on improving your quality of life. Rush @ Home:If you're unable to come to our office, we can come to your home through our Rush @ Home program. Through the program, a geriatrician and a primary care provider can come to your house to give you a medical assessment and do any lab work, as needed. That way, you can stay active and engaged in your care, no matter where you live.", "pred_label": "__label__POS", "pred_score_pos": 0.5064774751663208}
{"content": "1. It's the ultimate stress buster. Research shows the practice can reduce stress levels, lower blood pressure and even reduce symptoms of more serious mental health issues like anxiety. 2. It's a powerful workout.If you don't believe that, try any yoga class using the words \"power\" or \"strength\". Those sessions will leave you sweating. 3. It's good for weight management.Whether you want to lose some pounds or maintain a healthy body weight, yoga can do it for you. 4. It's great cross training.If you like to job, bike, swim, hike then bring yoga into the mix. It will strengthen muscles you're not utilizing in your regular workout. 5. It's a natural pain reliever.Neck pain, knee pain, back pain, hip pain.... Wherever you hurt and ache, yoga provides a natural relief. Yoga even helps with chronic pain, according to Harvard Medical School. It 6. It relieves headaches, especially migraines.Studies report that yoga helped reduce the frequency and intensity of migraines in sufferers. 7. It strengthens and stretches.That leads to a healthy, balanced body. If your workout consists of just one activity, then it's likely you're getting tighter and tighter, more rigid in body and mind. 8. It will bring new, good people into your life.Yoga is like a magnet attracting the nicest, kindest, most compassionate people on the planet to the practice. A yoga class is a great way to meet great people. 9. It will make you stronger .... in body, mind, and spirit.Your confidence will grow allowing you to better deal with life's challenges. 10. It leads to a happier state of mind.There is a 'mystical' aspect of yoga which generates joy, happiness, peace. Science talks about endorphins but it's more than that. Please come to my yoga classes: Saturday 9 am - 10:15 am Monday 7 pm - 8:15 pm. Namaste.", "pred_label": "__label__POS", "pred_score_pos": 0.5243284702301025}
{"content": "The NEAT team offers a variety of Assistive Technology (AT) services for all ages and abilities. AT Specialists conduct services in specialty areas but will collaborate when the needs of individuals require it. Services are conducted in-person, virtually, or through a hybrid delivery approach.\nWe help individuals compensate for any difficulties they have, including:\nLearning (Dyslexia, Dysgraphia, Dyscalculia, etc.) Physical Vision & Hearing Attention & Executive Functioning Intellectual Unique & Complex Needs\nFor more information about NEAT's AT services, or to request a specific service, please contact us at CentersConnect@OakHillCT.org.\nCollaborative, semi-formal meetings between AT specialists, support staff/educators, families, and/or individuals with disabilities. Consultations are designed to guide the team through a series of demonstrations and trials of AT tools that could help the individual gain or increase independence. These meetings will result in a set of\nsuggested tools and/or strategies.\nBenefits:\nCan be for an individual or a team of professionals Identify how to effectively use available technologies Technical support and troubleshooting for current technology Ongoing consultations can maximize AT capacity and confidence\nA written summary is not included but can be requested for an additional fee.\nNote: Consultations are typically conducted in-person, but virtual consultations can be effective for certain individuals. Please contact us for options.\nCustomized support in learning how to use specific assistive technology tools that address the needs of individuals with disabilities. AT training is reserved for individuals and their support team (up to 3 people).\nThis can be an effective follow-up to suggestions made during a consultation or recommendations made during an evaluation.\nNote: Coaching/training is typically conducted in-person, but virtual coaching/training can be effective for certain individuals. Please contact us for options.\nA structured fusion of consultation and coaching/training services. An AT Kickstart provides an individual and the support team with direct guidance during the beginning stages of assistive technology implementation.\nTypically, the AT Kickstart service includes 2 hours of consultation, a written summary of suggested tools, and 2 hours of follow-up coaching/training.\nNote: AT Kickstart meetings are typically conducted in-person, but virtual meetings can be effective for certain individuals. Please contact us for options.\nA formal, multi-step process that is led by an AT specialist and results in a set of technology recommendations and/or strategies that will meet the needs of an individual with disabilities.\nBenefits:\nCompletely individualized Includes a review of records, individual history, learning modalities, personal preferences, and a pattern of strengths and concerns Includes a team meeting to help identify AT needs Includes environmental observations and AT trials Provides comprehensive recommendations on appropriate technology supports for targeted skill sets Provides implementation strategies for meaningful access and participation\nA comprehensive written report with recommendations is included.", "pred_label": "__label__POS", "pred_score_pos": 0.8505201935768127}
{"content": "Objective: The ideal small-caliber arterial graft remains elusive despite several decades of intense research. A novel approach to the development of small-caliber arterial prostheses with a biomimetic system for in vitro vessel culture has recently been described. In this study we examined the effects of culture time and tissue culture scaffolding on engineered vessel morphology and function and found that these parameters greatly influence the function of engineered vessels.", "pred_label": "__label__POS", "pred_score_pos": 0.6874313354492188}
{"content": "‘Re-entry’ to a home culture after foreign mission is an unsettling time. A time of contrasts: excitement and anxiety, relief and guilt, hope and grief. When Seasons Change is a series of devotionals written to help navigate such times. Throughout the book (designed to be read over 10 weeks) Lyons aims to journey through that challenging time with the reader. Although overtly aimed at those returning from foreign mission, the wider concepts and processes engaged could also be very helpful for anybody making a significant transition within full-time ministry such as change of primary role, location or retirement.\nAs you journey through the gospel of Mark, Lyons draws from her personal experience to discuss themes and ask questions that occupy the mind of the returning missionary. Her valuable insights into Jesus’ ministry through the lens of re-entry are enlightening, edifying and encouraging. Many thought processes that those returning from foreign mission grapple with are identified in the daily devotionals. For the more reflective journal-writer or contemplative, there are springboard questions to provoke further thought and reflection for that day. For the more experiential learners, there are practical action steps. Each week ends with a summary of the themes covered and concrete advice on specific steps to take in order to care for yourself, connect with others and focus on personal spirituality during the following week.\nAs a tool, I believe Lyons offers a gateway to a healthy, reflective re-entry process. Just a brief read facilitates bringing some of the internal re-entry chaos back into order. The complexity of this ministerial reality is experienced by many returners, but it is rarely expressed and addressed in such relatable, simple terms with such insightful, practical and methodical advice. When Seasons Change reminds the reader that this time may feel like things are falling apart, but re-entry is a time to invest, to reflect and to allow God to build.", "pred_label": "__label__POS", "pred_score_pos": 0.9935823082923889}
{"content": "Abstract\nWe used data from the San Antonio Family Heart Study to determine the HDL correlates of the insulin resistance syndrome (IRS), as reflected by insulin concentrations in nondiabetic subjects. We measured insulin concentrations both in the fasting state and 2 hours after a glucose challenge (2-hour insulin) and we assessed seven aspects of HDL phenotype, including size and concentration of both lipid and protein components. Measurements were obtained from 1202 nondiabetic members of 42 families. Initial quantitative genetic analyses revealed that a substantial portion of phenotypic variation in the nine variables was due to genes (heritabilities, h\n2, ranged from 0.32 to 0.47). We then conducted a series of bivariate genetic analyses, which indicated that there were significant additive genetic correlations (ie, pleiotropy) between the two measures of insulin and five of seven HDL measures tested, including concentrations of HDL cholesterol (fasting insulin only) and triglyceride, and HDL size distributions of apoAI, apoAII, and cholesterol; concentrations of apoAI and apoAII were not genetically related to either insulin measure. Increased insulin levels were associated with relatively smaller HDL phenotypes, and considering a similar association with small, dense LDLs, this finding suggests a common effect of insulin resistance on particle size distributions for these lipoproteins. Thus, these results suggest the existence of genes that pleiotropically influence variation in both HDLs and insulin levels and therefore contribute to the clustering of proatherogenic traits in the IRS.\nOriginal language English (US) Pages (from-to) 3414-3419 Number of pages 6 Journal Arteriosclerosis, Thrombosis, and Vascular Biology Volume 17 Issue number 12 DOIs State Published - 1997 Keywords Diabetes Gradient gel electrophoresis HDL Insulin ASJC Scopus subject areas Cardiology and Cardiovascular Medicine", "pred_label": "__label__POS", "pred_score_pos": 0.8231272101402283}
{"content": "How Do I Maximize the Sales Price of My Company?\nMaximizing the sales price of a business involves focusing on the “value drivers” of the industry. Value drivers are the set of key factors that reduce financial risk, improve financial returns and create value for the company. These aspects are used by buyers, investors and financial lenders to determine the value of a company. Value drivers are not unique to maximizing the sales price of companies but are sound business practices.\nValue drivers for all industries include: a solid diversified customer base, a strong management team, operating systems that improve the sustainability of cash flows, an achievable growth strategy, a facility appearance consistent with the sales price and effective financial controls.\nIndustry specific value drivers include: extent of referral network, certifications, competition, specialized processes, geography served, affiliations, environmental issues, growth opportunities, seasonality, supplier relationships, equipment quality, technological expertise and backlog of contracts.\nThe sale of one’s business may be the most significant financial transaction of an owner’s life. Early planning for effectively maximizing the sales price of a business is the first step in a successful exit plan.", "pred_label": "__label__POS", "pred_score_pos": 0.7105525732040405}
{"content": "Topic of Study [For H2 History Students]:\nPaper 1: Understanding the Cold War (1945-1991) Section A: Source-based Case Study Theme I Chapter 2: A World Divided by the Cold War – Manifestations of the global Cold War: Vietnam War (1955-75)\nTopic of Study [For H1 History Students]:\nEssay Questions Theme II Chapter 2: The Cold War and Southeast Asia (1945-1991): The Second Indochina War (1964-1975) Contextual Analysis In the previous article, we have examined the historical developments of the first and second Indochina Wars. Next, it is imperative to consider the political impacts of the Vietnam War on the superpowers – USA and Soviet Union. 1. Impacts on the USA: ‘Vietnam Syndrome’ Notably, the withdrawal of USA from Vietnam was largely influenced by anti-war sentiments. Many young Americans were against the drafting process. Also, the growing disillusionment and exposed war atrocities (especially the ‘My Lai massacre’) created the impetus for citizens to demand the immediate withdrawal.\nFurthermore, critics questioned the necessity of US involvement in the politics of other countries even though many still supported the notion of ‘defending democracy’. As these doubts surfaced, some argued that US Presidents should not be given extensive powers to wage wars without Congress approval.\n1.1. The War Powers Act In November 1973, the War Powers Act (also known as the ‘War Powers Resolution’) was passed as a congressional resolution to curtail the US President’s ability to conduct foreign military campaigns. Its main purpose was to prevent US from being trapped in costly and protracted wars, like the conflict in Vietnam.\nThis Act required the president to seek congressional approval before American troops can be deployed overseas. For instance, the President has to inform the Congress within 48 hours.\nAlthough President Nixon vetoed the law by claiming that it was ‘unconstitutional and dangerous’, the Congress overrode his action.\nHowever, the congressional resolution proved futile as future US Presidents found ways and means to circumvent it. For example, President Ronald Reagan deployed troops in El Salvador in the 1981, during the renewed confrontation with the Soviets.\n1.2. The Detente\nOn 22 May 1972, Nixon visited his Cold War rival, Leonid Brezhnev in Moscow. It marked the first-ever visit by an American president to Soviet Union. The key takeaway from these visits was the increased mutual cooperation.\nFor example, the Strategic Arms Limitation Talks (SALT I) Agreement was signed on 26 May 1972. The Agreement signified the mutual decisions of the superpowers to halt the build-up of strategic ballistic missile launchers. The SALT II Treaty was signed later in the 1970s that banned the development of new ballistic missiles for both countries.\nAlso, this phase of the Cold War led to the push for space exploration. In July 1975, both USA and USSR conducted a joint-space flight and encouraged collaboration.\nHowever, the thawing of superpower relations halted when Soviet Union invaded Afghanistan in December 1979. Tensions resurfaced as USA boycotted the 1980 Summer Olympics in Moscow.\n2. Impacts on the USSR: Race in the Third World On the other hand, the Second Indochina War prompted the Soviet government to intensify its efforts to support the Communist regime. Ho Chi Minh’s victory in Indochina was hailed as a significant victory against the Americans.\nAs such, Soviet Union raised its military expenditures to support its Cold War allies. As stated earlier, its campaign in the Third World regions began with the invasion in Afghanistan. This conflict was a turning point as observers noted that Soviet Union invaded a country outside the Eastern Bloc, such that its actions drew international criticisms.\nThe Soviet occupation of Afghanistan was carried out with the intention to reinforce the Brezhnev Doctrine, in which the government seems to secure its political influence in these socialist countries.\nHowever, the campaign in Afghanistan proved disastrous for Soviet Union. The protracted conflict was perceived by some historians as “Soviet Union’s Vietnam War”, particularly due to the mounting economic costs.\nWhat can we learn from this article? Consider the following question: – Assess the political significance of the Second Indochina War on the USA [to be discussed in class].\nBesides the topical review of this Cold War event, it is important that you attempt source-based case study questions or essay questions to determine whether you have fully understood these historical developments. Join our JC History Tuition and get additional support as we provide numerous practice questions and answer outlines. By doing so, we ensure that you can study productively and effectively to perform well for the GCE A Level History examinations.\nAlso, you can join our JC tuition programmes, such as GP Tuition, Economics Tuition, JC Chemistry Tuition, JC Math Tuition and China Studies in English Tuition. For Secondary Tuition, we provide Secondary English Tuition, Secondary Math tuition, Secondary Chemistry Tuition and Secondary Economics Tuition. Call 9689 0510 to learn more!", "pred_label": "__label__POS", "pred_score_pos": 0.9580851793289185}
{"content": "You will learn how to work effectively with stress, be it related to illness or working within the health care system. By participating with others, engaged in similar challenges, you can bring to bear in your life both the uniting force of community and the solace and power of your own inner strength. In this way, you can actively encourage the healing process.\nThe program teaches participants to use their innate resources and abilities to respond more effectively to stress. It includes intensive training in mindfulness meditation and its integration into the challenges of daily life and medical practice. Delivered online on ZOOM or in-person, if possible given the pandemic.\nRead more.", "pred_label": "__label__POS", "pred_score_pos": 0.6246219873428345}
{"content": "As a 14-year volunteer with the BCSPCA/Wild ARC, I have retrieved many animals killed by rat poison. One of the saddest incidents was a large, beautiful barred owl found dead on my own property, beside a partially eaten rat. A necropsy on both determined the cause of death was due to rat poison.\nThe most disturbing recovery of all was a family of hawks from the Willows Beach area. All three had been killed by rat poison and their bodies thrown in a dumpster, along with miscellaneous garbage. Locals were understandably distressed; the hawks were well known in the park and considered an important part of the environment.\nBirds of prey are integral to the ecosystem. It is crucial to protect them and their habitats as they are essential in helping control rodent populations.\nAlternative Wildlife Solutions (www.alternativewildlifesolutions.com) are a local company offering humane remedies for dealing with wildlife conflict issues. They do not use rat poison and no animals are harmed or killed. If only all “pest control” companies in Greater Victoria could be mandated to follow their lead.\nKerri Ward\nOak Bay", "pred_label": "__label__POS", "pred_score_pos": 0.8171542882919312}
{"content": "Rebekah Borgoyary\nRebekah is a research scholar and is currently pursuing her PhD from Jawaharlal Nehru University, New Delhi. Her research encompasses tribal identities, women and their role in the identity-making process.\nShe is interested in exploring the question of women’s agency and autonomy in ethno-nationalist movements of Northeast India. Apart from academics, she likes to engage in searching for stories on the grassroots level on issues related to marginality in nation-making, with a focus on Bodo women in Assam.\nConverging Space of Paid and Unpaid Labour\nI came across this sight in a border village called Saralpara, which runs along the Indo-Bhutan border, situated in Kokrajhar district in the state of Assam. The picture explores the theme of ‘invisible labour of women’, where the boundaries between home and the workspace is indistinguishable. The disproportionate labour burden that women shoulder between unpaid care work and income-generating work is one of the strong pillars of patriarchy, which consistently keeps women from realising their rights and equality. Caring for a child is one of the most common unpaid work undertaken by women as the gendered roles are deeply embedded in familial settings. While the pandemic has forced people to stay at home and the lockdown has made economic activities difficult, a woman tries to run her tea shop with her child sleeping in a cradle hung from the ceiling in a remote village where no cases of coronavirus have been detected yet.\nAs she tries to meet her daily earnings in times of lockdown, it converges with her domestic unpaid care work of nurturing her child. The enduring unpaid care work converging with her workspace reflects the integral relationship of a woman and her labour; trying to make room for her gendered role and economic sustainability at once.\nThis leads to a ‘double burden’ where a woman’s responsibilities increase but income does not.\nIt also shows the class nature of care, where many upper-class women have the option of ‘additional’ care rendered by helpers and leave their child behind at home, whereas women in margins rendered by socio-economic conditionality can’t afford assistance or leave them behind at home. Pandemic or no pandemic, the skewed labour division continues and the disproportionate responsibilities that women shoulder continues", "pred_label": "__label__POS", "pred_score_pos": 0.6623853445053101}
{"content": "Últimas fotos Niger | Launch of FAO’s emergency agricultural activities and response to the pastoral lean season in the Niger’s regions of Diffa, Maradi, Tahoua and Zinder26/11/2020 Afghanistan | FAO supports agriculture-based livelihoods to mitigate the impacts of COVID-1924/11/2020 Ethiopia | Desert locust control operations11/11/2020 Kenya | Desert locust control operations11/11/2020 FAO and Rohingya refugees restore forests in and around once barren camps20/10/2020 Síguenos en Destocking campaign in Ethiopia Tags: ETHIOPIA, EASTERN AFRICA, HORN OF AFRICA, EL NIÑO-LA NIÑA, EL NIÑO 2015/16, CRISIS, DROUGHT, PASTORALISTS, INCOME GENERATION, DESTOCKING, LIVESTOCK, LIVESTOCK MORTALITY, OSRO/ETH/503/BEL, RESOURCE PARTNERS, BELGIUM, PHOTO STORY,\nIn\nSomali Region of southeastern Ethiopia, the ongoing drought – the most severe in half a century due to the effects of El Niño – has caused critical feed and water shortages, resulting in abnormal migrations and widespread livestock deaths. Most of the region’s population is dependent on animals as a source of both food and income, but as the lean season continues, these households are experiencing a rapid deterioration in food security and increased risk of malnutrition. Alarmingly, several families across the region reported sharing their food aid with their remaining livestock in an effort to help them survive.\nTo safeguard the livelihoods of pastoralists affected by the drought and provide time-critical support to the most in need, the Food and Agriculture Organization of the United Nations (FAO) has implemented an intervention in nine communities of three of the worst-affected districts of Siti Zone – Erer, Hadagala and Shinile – in collaboration with the regional Livestock and Pastoralist Development Bureau. FAO aims to enhance the financial stability of 4 200 households and nutritional intake of 4 500 households through the purchase of livestock and provision of protein-rich meat.", "pred_label": "__label__POS", "pred_score_pos": 0.7717547416687012}
{"content": "Never has there been a greater need for writers who can communicate about the environment in such clear, immediate and powerful ways, who can envisage the past as well as the future.\nThe contributors to this issue all have a deep understanding of how nature works. Some are scientists; others, environmental journalists exploring the latest thinking about ecosystems and how to repair them; or poets, novelists and activists examining our responses to the current crisis.\nThe knowledge is already out there. We just have to listen.", "pred_label": "__label__POS", "pred_score_pos": 0.725039005279541}
{"content": "A true compass always points to the magnetic north pole – that fixed location by which travelers and explorers confidently orient for direction no matter the surrounding circumstances. For nearly 240 years, the United States has uncompromisingly placed its trust in God – a spiritual true north that has likewise anchored our moral compass. This simple act of humble confession, derived from deeply held Judeo-Christian values, has offered strength in wartime, dignity and compassion toward those less fortunate, solace in times of national grief and hope in the face of unprecedented challenges. We see these principles woven into the very fabric of our founding documents. They give substance to the liberties we all cherish and echo in the speech and prayers of godly patriots who rose up together at the birth of America.\nThese were the same individuals who penned the Declaration of Independence, designed the Constitution, orchestrated each significant Amendment and crafted the Bill of Rights. There was no impassioned argument calling for the removal of God from the affairs of men, no disdain in setting aside the work of government to beseech God’s wisdom and direction on bended knees, no angst over publically recognizing His influence in life and culture. To imply otherwise is a distortion of the historical narrative and would require a complete suspension of the truth.\nPresident and signer of the Declaration of Independence, John Adams, said this about America’s liberty, “Statesman may plan and speculate for liberty, but it is religion and morality alone that can establish the principles upon which freedom can securely stand.” If he is right, then it no wonder that the majority of American’s believe our nation is going in the wrong direction.\nPresident Ronald Reagan understood, “Freedom is never more than one generation away from extinction. Without God there is no virtue because there is no prompting of the conscience…without God there is a coarsening of the society; without God democracy will not and cannot long endure…If we ever forget that we are One Nation Under God, then we will be a Nation gone under.” Today, the battle for faith and religious freedom has been elevated to the forefront of our national discourse. For years now, there have been targeted efforts to remove God from the marketplace of ideas and practice.\nWhile religious persecution against any faith should be vigorously condemned at every turn—and we often do so when it targets the innocent adherents of Islam and Judaism—today, across many parts of the world, arrests, imprisonment, re-education camps and even extreme acts of barbarism by cowardly terrorists, such as the beheading of children, are all too common atrocities being perpetrated upon people of faith who hold Christian convictions.\nMany continue to deny this could never happen within the United States. However, just a few short decades ago, most citizens also never envisioned an America where the Ten Commandments would be reviled in our court houses, where businesses had to accept mandatory healthcare provisions that violate the conscious or the sanctity of life, where activist outcries are made over a humble nativity in a public park at Christmastime, valedictorians having their speeches scrubbed of all religious terminology, a pastor being threatened with arrest for holding a Bible study in his home, military chaplains facing court martials for praying in the name of Jesus, even students being suspended for simply saying, “Bless you” after a classmate sneezed…and the list could go on.\nThe phrase, “In God We Trust,” first drawn from The Star Spangled Banner in 1812, has been engraved on our currency since 1864 and was adopted as the National Motto in 1956. On November 1, 2011, the U.S. House of Representatives, under the leadership of Congressmen, J. Randy Forbes (R-VA) and Mike McIntyre (D-NC), along with 64 other bipartisan cosponsors, voted overwhelmingly (396-9) to reaffirm these historic words as the official motto of the United States. Yet, the anti-faith movement—who wrongfully misapply Jefferson’s comments regarding the Separation of Church and State—relentlessly seek to induce a sense of public shame and conjure up images of radical intolerance among those who hold biblical beliefs.\nInspired by the landslide vote, the Congressional Prayer Caucus Foundation has launched the “In God We Trust. Put It Up!” initiative as part of a proactive strategy supported by government leaders, celebrities, and faith-based organizations as a way to protect God’s enduring and rightful place. To join the In God We Trust MILLION WINDOW Campaign, go to www. InGodWeTrust.com. The United States lies at the threshold of a significant crossroad: either to acknowledge and embrace the vibrant character of our spiritual heritage or to plunge headlong into the postmodern void—a value neutral and amoral vacuum that seeks to deconstruct much of what we consider sacred. Will you be an American patriot of the 21st Century?\nYou can join millions of Americans who are affirming their trust in God – and the freedom to proclaim it – by displaying this 3″ x 6 ” window decal in your home, office or vehicle. Actual decal has clear background.", "pred_label": "__label__POS", "pred_score_pos": 0.6942923069000244}
{"content": "This research investigated yeast populations and diversity during pre-fermentation cold maceration and alcoholic fermentation of Vitis vinifera L. cv. Pinot noir grapes from a commercial vineyard (Dayton, OR). Fermentations were conducted at the Oregon State University research winery in 100 L tanks while grapes from the same vineyard lot were fermented at a commercial winery. Samples were taken daily during pre-fermentation maceration (9°C) and alcoholic fermentation (27°C) and plated on WL and lysine media to determine Saccharomyces and non-Saccharomyces populations and diversity. Total non-Saccharomyces populations increased from 1 x 10³ cfu/mL to 1 x 10⁵ cfu/mL during pre-fermentation cold maceration and reached a maximum of 1 x 10⁷ cfu/mL during alcoholic fermentation. Thirteen distinct yeast species were tentatively identified based on appearance on WL media and were initially screened for β-glucosidase activity using 4-methyllumbelliferyl-β-D-gluconopyranoside (4-MUG) plates. The identity of the isolates screening positive for β-glucosidase activity was determined by sequence analysis of the D1/D2 domain of the 26S rDNA gene. The five isolates identified were Metschnikowia pulcherrima, Hanseniaspora uvarum, Kluveromyces thermotolerans, and two Saccharomyces cerevisiae isolates. β-glucosidase activity was further characterized and quantified using a liquid media representing grape must conditions (pH 3.5, 20° Brix) at two temperatures (25°C and 8°C). While increasing sugar concentration suppressed the β-glucosidase activity of H. uvarum (-99%), β-glucosidase activity still remained relatively high for M. pulcherrima, S. cerevisiae isolate 1, and S. cerevisiae isolate 2. At 8°C, β-glucosidase activity was reduced for M. pulcherrima compared to activity at 25°C, but activity increased for K. thermotolerans, S. cerevisiae isolate 1, and S. cerevisiae isolate 2.The yeast isolates possessing β-glucosidase activity were used in fermentations of Vitis vinifera L. cv. Pinot Noir grapes. The grapes were treated with high hydrostatic pressure (HHP) to inactivate naturally occurring yeast and bacteria. All yeast isolates grew during pre-fermentation cold maceration (7 days at 9°C) and populations increased 3 to 4 logs. Following pre-fermentation cold maceration, all ferments were warmed to 27°C and inoculated with S. cerevisiae RC212. Alcoholic fermentations were all complete within eight days and after pressing wines were analyzed for volatile aroma compounds by SPME-GC-MS. The presence of different yeast isolates during pre-fermentation cold maceration resulted in wines with unique aroma profiles. Ethyl ester concentrations were highest in the wine that did not undergo a pre-fermentation cold maceration, while concentrations of branch-chained esters were higher in the treatments with yeast present during pre-fermentation cold maceration. Pre-fermentation cold maceration with yeast isolates demonstrating β-glucosidase did not affect the concentration of β-damascenone or β-ionone. Wines that had undergone pre-fermentation cold maceration with S. cerevisiae isolate 1, S. cerevisiae isolate 2, and a combination of all isolates resulted in over twice the concentration of β-citronellol over wines that did not undergo a pre-fermentation cold maceration.", "pred_label": "__label__POS", "pred_score_pos": 0.7238825559616089}
{"content": "Trend in corn prices\nCorn futures contracts for March 2016 expiry were trading near the crucial support of $3.70 per bushel on February 4, 2016. Prices fell for the second consecutive trading day. They fell below the critical support. The volume of the contracts rose by 18.6%. The open interest fell slightly by 0.39% on February 4, 2016. Prices trade above the 20-day and 50-day moving averages of $3.65 and $3.67 per bushel on February 4, 2016. The prices are expected to remain in the projected channel.\nThe above chart indicates that prices could be $3.75–$3.65 per bushel in the short term.\nPrice drivers\nDespite a strong weekly export sales report from the U.S. Department of Agriculture, corn prices fell on February 4, 2016. CONAB, Brazil’s National Food Supply Agency, raised the 2015–2016 corn production by 1 million tons. It pushed US soybean prices down. Statistics Canada reported that the inventory for marketing year 2015–2016 could fall by 17% and impact corn prices.\nIn contrast, the US dollar depreciated by 0.81% on February 4, 2016. It supported the corn export sentiment.\nStocks review\nThe fall in corn prices pushed the corn inventory’s value down for corn trading and producing businesses. Tyson Foods (TSN) fell by 1.8% on February 4, 2016, for the third consecutive trading day. During the period, it fell by 4.4%. Ingredion (INGR) and ConAgra Foods (CAG) fell by 1.1% and 2.7% on February 4, 2016. They continued to drag prices down from the upward channel. However, CHS (CHSCP) recovered from the fall the previous day. It rose slightly by 0.10% on February 4, 2016. The PowerShares DB Agriculture Fund (DBA) continued its downward movement. It fell by 0.50% on February 4, 2016.", "pred_label": "__label__POS", "pred_score_pos": 1.0000059604644775}
{"content": "The Carbon Cleaning Revolution!\nModern engine design, coupled with a drive to reduce harmful emissions, has led to a significant increase in contamination related issues such as\nBlocked DPF’s Fouled Fuel Injectors MOT emission failures\nOur carbon cleaning service helps to prevent this build up allowing you to eradicate these costly issues\nA significant saving in your motoring costs! Why Carbon Clean? Cleaning the carbon from your car’s engine every once in a while is a very good idea, giving you the benefits of increased performance, improved fuel economy and the reduced likelihood of a breakdown as well as benefits to the environment due to the reduction in harmful emissions.\nAny vehicle that has covered more than 10,000 miles, or is used regularly for ’round town’ driving, benefits from having a “Carbon Clean” – particularly Diesel vehicles fitted with DPF’s.\nA typical carbon clean will improve fuel economy by up to 10%, saving the average motorist approximately £200 per year in improved fuel economy.\nFor more information give us a call on 0333 733 1400", "pred_label": "__label__POS", "pred_score_pos": 0.5248678922653198}
{"content": "Beneath a towering granite pavilion, in the smallest state park in Massachusetts, is an unassuming gray boulder with outsized historic and economic importance: Plymouth Rock.\nThe Rock draws a million visitors a year. Tourism is a powerful economic engine for Plymouth, employing 4,000 workers and generating $30 million annually in local taxes.\nFive miles down the coast is Rocky Point, and the town’s other giant economic engine: Pilgrim Nuclear Power Station. Pilgrim is the second-largest private employer in Plymouth. Its approximately 600 workers take home an average paycheck over $100,000 — double the typical wage in town. And the plant pays the highest property taxes in Plymouth.\nIn May, the nuclear plant is shutting down for good. And Plymouth — known as “America’s Hometown” — will have to adjust to life post-Pilgrim.", "pred_label": "__label__POS", "pred_score_pos": 0.7507270574569702}
{"content": "Cognitive-behavioral treatment reduces attrition in treatment-resistant obese women: results from a 6-month nested case-control study. OBJECTIVE: The aim of this nested case-control study was to compare the effectiveness of cognitive-behavioral treatment (CBT) for treatment-resistant obese (body mass index [BMI] ≥ 30 kg/m²) women compared with standard dietary treatment. The main outcome measures were attrition and weight loss success. METHODS: We designed a 6-month case-control study, nested within a cohort of adult (age ≥ 18 years) treatment-resistant (history of at least two previous diet attempts) obese women. Cases were 20 women who were offered CBT sessions. Controls (n=39) were randomly selected from the source population and matched to cases in terms of baseline age, BMI, and number of previous diet attempts. RESULTS: Compared with controls, cases were significantly more likely to complete the 6-month program in both age-adjusted (odds ratio [OR]=2.94, 95% confidence interval [CI]=1.05-8.97) and multivariate-adjusted (OR=2.77, 95% CI=1.02-8.34) analyses. In contrast, cases were not more likely to achieve weight loss success in age-adjusted (OR=1.32, 95% CI=0.86-1.67) and multivariate-adjusted (OR=1.21, 95% CI=0.91-1.44) analyses. CONCLUSIONS: Compared with a standard dietary treatment, CBT was significantly more effective in reducing attrition in treatment-resistant obese women, without differences in terms of weight loss success....", "pred_label": "__label__POS", "pred_score_pos": 0.7929707765579224}
{"content": "When crises occur, empowerment of the individual is rarely thought of as the solution.\nYet, fulfilment of society depends on the individual.\nThe individual is concrete, while society is not.\nSociety cannot flourish if individuals do not prosper.\nPeople face today significant barriers in most ambits of their life: occupation, health, education, etc.\nEMPOWERMENT is the answer.\nOn this subject, and more specially on the housing crisis, you can read:", "pred_label": "__label__POS", "pred_score_pos": 0.7890233397483826}
{"content": "13 July 2020\nAs the world’s economy becomes increasingly transnational, and debtors, their assets, and creditors are scattered across multiple jurisdictions, the need for consistency and efficiency in the cross-border administration of insolvency proceedings has become more pressing. Variations among legal systems have resulted in inconsistent, duplicative, time-consuming and costly efforts to recognise and enforce insolvency-related judgments in different jurisdictions, creating legal uncertainty and other complications in the administration of cross-border insolvency proceedings.\nThe United Nations Commission on International Trade Law (UNCITRAL) attempted to foster international cooperation in the administration of cross-border insolvencies through its Model Law on Cross-Border Insolvency (MLCBI), but there remained an ambiguity in the recognition and enforcement of judgments related to insolvency proceedings, especially where enforcement of the foreign judgment was inconsistent with local law.\nThe Model Law\nAs a result, in 2014, UNCITRAL gave a mandate to its Working Group V on Insolvency Law to develop a model law that specifically provides for the recognition and enforcement of insolvency-related judgments. The Working Group collaborated with UNCITRAL’s 60 member states and the representatives of 31 observer states and 34 inter-governmental and non-governmental organisations to develop the Model Law on Recognition and Enforcement of Insolvency-Related Judgments .\nOn 2 July 2018, UNCITRAL adopted the Model Law, which is designed to address both the gap in international law regarding the cross-border recognition and enforcement of judgments that arise as a consequence of, or are materially associated with, insolvency proceedings; and the uncertainty in interpreting certain provisions of the MLCBI “in terms of providing the necessary authority for such recognition and enforcement as a form of relief available on recognition of a foreign insolvency proceeding.”\nHow the Model Law works\nThe Model Law seeks to address these issues through its primary characteristics: harmonisation and flexibility. It offers enacting states a “simple, straightforward and harmonised procedure for recognition and enforcement of insolvency-related judgments” while remaining flexible in its integration into each enacting state’s legal system. Importantly, the Model Law is intended to supplement the MLCBI, and in fact mirrors its provisions and definitions in many respects, as well as the existing legal frameworks of the enacting states.\nFor example, as international insolvency practitioners, we know the terminology used in insolvency proceedings can vary by jurisdiction. Where a term or expression is likely to vary among enacting states, the Model Law offers more inclusive defined terms, such as “insolvency proceeding” (as opposed to liquidation, reorganisation or bankruptcy) and “insolvency representative” (rather than trustee, foreign representative, liquidator, judicial administrator etc). It also describes terms or expressions in brackets as placeholders for jurisdiction-specific information – like the name of the court, body, or authority designated to perform the specified function – allowing the enacting state’s legislators to use the term specific to that jurisdiction.\nAdditionally, the Model Law offers optional provisions, such as one allowing the enacting state to refuse the recognition of an insolvency-related judgment when it originates from a state whose “insolvency proceeding” would not be subject to recognition under the MLCBI.\nThe Model Law also contains two noteworthy exceptions to recognising and enforcing insolvency-related judgments. Enacting states may refrain from taking any action that would be “manifestly contrary” to their public policy. Further, the Model Law enumerates the following specific grounds for the refusal of recognition and enforcement:\nimproper notice to the defendant in the proceeding that gave rise to the insolvency-related judgment; the judgment was obtained by fraud; the judgment is inconsistent with a judgment entered in the enacting state involving the same parties; the judgment is consistent with an earlier judgment entered in another state involving the same parties and subject matter; recognition and enforcement would interfere with the administration of the debtor’s insolvency proceeding; the judgment materially affects the rights of creditors generally and their interests were not adequately protected in the proceeding that led to the judgment; and the court issuing the judgment did not have jurisdiction. Defining an “insolvency-related judgment”\nAs its name suggests, the Model Law’s distinguishing feature is that it applies to “insolvency-related judgments”, which previously had not been fully addressed by other UNCITRAL insolvency texts. The Model Law provides a broad definition of “judgment” to include any decision, such as a decree, order, or determination of costs and expenses, “issued by a court or administrative authority”. To fall within the Model Law’s scope, an insolvency-related judgment must “arise… as a consequence of or [be] materially associated with an insolvency proceeding”, and be “issued on or after the commencement of that insolvency proceeding”. Importantly, the judgment must have been rendered in a proceeding in a state other than the enacting state in which recognition and enforcement are sought; the location of the insolvency proceedings to which the judgment relates is immaterial.\nThe Model Law’s Guide to Enactment provides a non-exhaustive list of judgments that fall within the definition of “insolvency-related judgment”, including judgments dealing with the constitution and disposal of assets in the insolvency estate; judgments determining whether a transaction involving the debtors or assets of its insolvency estate should be avoided because it was a preferential transaction or a transaction at an undervalue; judgments involving a director or representative liability for the debtor’s actions while insolvent or in the period approaching insolvency; judgments determining that sums are owed to or by the debtor or the insolvency estate; judgments confirming or varying a plan of reorganization or liquidation or approving a voluntary or out-of-court restructuring agreement; and judgments for the examination of a director of the debtor, where that director is located in a third jurisdiction.\nDecisions or orders commencing insolvency proceedings and interim measures of protection are explicitly excluded from the Model Law’s scope. Further, it is unclear whether insolvency-related arbitral decisions are considered “insolvency-related judgments” under the Model Law, as they may not come from an “administrative authority.”\nThe Model Law’s impact and success\nWhile it is still too early to evaluate the Model Law’s impact and success, its design as a supplement to the MLCBI and the enacting state’s existing legal structure, rather than an overhaul of existing insolvency frameworks, suggests that it will succeed (at least partially) in making the recognition and enforcement of insolvency-related judgments more consistent and efficient. Moreover, though the Model Law intends to respect the insolvency schemes of the respective enacting states, UNCITRAL cautions against excessively modifying the Model Law and frequently invoking its exceptions. That said, enacting states are still free to make the necessary modifications to protect their own legal processes and domestic creditors, which could result in the very complications the Model Law was intended to eliminate.\nThe Model Law’s success also depends on the number of states that enact it. By way of comparison, over 45 jurisdictions have adopted the MLCBI, including Australia, Canada, Colombia, Japan, Kenya, Mexico, New Zealand, the Republic of Korea, Singapore, South Africa, the UK, BVI, Gibraltar, and the US; however, several European nations have not adopted it and are governed by the separate EU regulation (EC No. 1346/2000) on insolvency proceedings. This same EU regulation provides for the recognition and enforcement of judgments that “derive directly from and are closely linked to… insolvency proceedings”. Because this EU regulation seems to address the recognition and enforcement of insolvency-related judgments, and several European nations have opted to implement its framework and rejected the MLCBI, it is unlikely that these same nations will adopt the Model Law.\nFinally, as mentioned above, it is unclear whether insolvency-related arbitral decisions fall within the scope of the Model Law. As the law develops and the Working Group continues to issue guidance on its enactment, practitioners should expect to see developments on this issue.", "pred_label": "__label__POS", "pred_score_pos": 0.6719567775726318}
{"content": "Temporary bridge enables full vehicular and pedestrian access throughout construction\n(Toronto, Ontario) – 16 July 2020 – Acrow Bridge, a leading international bridge engineering and supply company, has announced that its Canadian company, Acrow Limited, recently designed and supplied a 112.6-meter-long three-span structure to minimize work zone traffic disruptions during a bridge replacement project in Bayfield, Ontario.\nThe Bayfield River Bridge, a 70-meter-long two-span deck truss bridge on Highway 21 was constructed in 1949. By 2017, it had reached the end of its service life and preliminary planning for a full replacement was initiated. As the route provides critical access not only for local residents but also for the region’s significant tourism industry, the approved project necessitated the installation of a temporary bridge to provide an on-site detour for vehicles and pedestrians while the replacement bridge was being rebuilt.\nThe modular steel detour bridge designed and supplied for the project consists of three spans of 18.3m, 76m and 18.3m for a total length of 112.6m, with a roadway width of 9.1m and a live load of two lanes of CL-625-ONT. The bridge has a TL-4 guardrail system, a 1.5m cantilevered sidewalk, and features an anti-skid epoxy aggregate deck surface.\nThe long length and heavy weight of the main span created numerous challenges to the launching and erection of the bridge. Due to the minimal footprint available to assemble components on-site, the components were delivered in stages to accommodate installation. The bridge was erected on rollers, with additional rollers on top of the piers required for ease of erection and a safe launch. The bridge was then moved to its final position, lowered and set on both abutment and pier bearings to complete construction.\nDelivered to contractor Looby Construction in mid-February, the rental bridge was constructed in about four weeks and opened to traffic on April 13. It will remain in service for a minimum of 10 months while a replacement bridge is being built.\n“In addition to the obvious safety benefits, detour bridges allow traffic to be maintained at full capacity and speed during construction, decreasing the impact on the traveling public and local businesses”, said Gordon Scott, Director of Operations and Sales, Acrow Limited. “They also offer significant cost-savings by helping ensure a project stays on schedule – a key benefit for both contractors and government agencies alike.”\nBill Killeen, Acrow CEO added, “The rental market has gained a strong foothold in the highway construction industry for its many benefits, and I will add to Mr. Scott’s words by writing that this Acrow bridge will also provide significant regional trade benefits through the flow of commerce not being restricted. Acrow modular bridges are also an ideal solution for use as permanent structures as they are manufactured with high strength, high quality U.S. steel from ISO-certified mills and galvanized to protect against corrosion.”", "pred_label": "__label__POS", "pred_score_pos": 0.6087486743927002}
{"content": "Abstract\nPURPOSE Burkitt lymphoma is an aggressive B-cell lymphoma curable with dose-intensive chemotherapy derived from pediatric leukemia regimens. Treatment is acutely toxic with late sequelae. We hypothesized that dose-adjusted etoposide, doxorubicin, cyclophosphamide, vincristine, prednisone, and rituximab (DA-EPOCH-R) may obviate the need for highly dose-intensive chemotherapy in adults with Burkitt lymphoma. METHODS We conducted a multicenter risk-adapted study of DA-EPOCH-R in untreated adult Burkitt lymphoma. Low-risk patients received three cycles without CNS prophylaxis, and high-risk patients received six cycles with intrathecal CNS prophylaxis or extended intrathecal treatment if leptomeninges were involved. The primary endpoint was event-free survival (EFS), and secondary endpoints were toxicity and predictors of EFS and overall survival (OS). RESULTS Between 2010 and 2017, 113 patients were enrolled across 22 centers, and 98 (87%) were high risk. The median age was 49 (range, 18-86) years, and 62% were $ 40 years. Bone marrow and/or CSF was involved in 29 (26%) of patients, and 28 (25%) were HIV positive. At a median follow-up of 58.7 months, EFS and OS were 84.5% and 87.0%, respectively, and EFS was 100% and 82.1% in low- and high-risk patients. Therapy was equally effective across age groups, HIV status, and International Prognostic Index risk groups. Involvement of the CSF identified the group at greatest risk for early toxicity-related death or treatment failure. Five treatment-related deaths (4%) occurred during therapy. Febrile neutropenia occurred in 16% of cycles, and tumor lysis syndrome was rare. CONCLUSION Risk-adapted DA-EPOCH-R therapy is effective in adult Burkitt lymphoma regardless of age or HIV status and was well tolerated. Improved therapeutic strategies for adults with CSF involvement are needed (funded by the National Cancer Institute; ClinicalTrials.gov identifier: NCT01092182).\nASJC Scopus subject areas Oncology Cancer Research", "pred_label": "__label__POS", "pred_score_pos": 0.5998947024345398}
{"content": "Walmart Foundation grants help build a food secure community and provide needed equipment to assist in the effort.\nCity of Santa Maria Mayor Alice Patino, County of Santa Barbara elected officials, the Foodbank’s board of directors and Walmart executives will attend the event.\nThe Foodbank has been awarded grants totaling more than $150,000 to help fund their “Building a Food Secure Community” project, enroll low income families in the SNAP program and increase their infrastructure with the purchase of a refrigerated van.\nAdditional support through food donations and volunteer support will also be recognized.\nWalmart and the Walmart Foundation provide donations of both food and funds to Feeding America and its nationwide member network of 200 food banks, including the Foodbank of Santa Barbara County.\nThese grants align with Walmart’s commitment to create a more sustainable food system, including a goal of providing four billion meals to those in need in the US over the next five years.\nWith food insecurity remaining high throughout the country, the ability to distribute more food is critical for food banks.\nAccording to the USDA, about 49 million people, including 16 million children, in the United States are food insecure, which means at some point during the year, they won’t know where their next meal will come from.\nIn Santa Barbara County, one out of four people receive some level of services from the Foodbank.\n“These funds are significant in the effort to build a food secure community, reaching youth, families and the community at large,” said Erik Talkin, CEO of Foodbank of Santa Barbara County. “The Foodbank acknowledges the Walmart Foundation for their recognition and support of these critical programs.”\nThe money awarded to Foodbank will go a long way in helping to fund 2016 programs, including expanding the organization’s food literacy programs, distributing produce to local families in need and ensuring that the community has access to a reliable source of produce year-round.\nThe event will be held at the Foodbank’s Santa Maria Warehouse, and it will also highlight the newly purchased Grocery Rescue van.\n—\nFoodbank of Santa Barbara County aims to transform health by eliminating hunger and food insecurity through good nutrition and food literacy.", "pred_label": "__label__POS", "pred_score_pos": 0.6014151573181152}
{"content": "Policy Rationale\nWe are consolidating several existing exploitation policies that were previously housed in different sections of the Community Standards into one dedicated section that focuses on human exploitation and captures a broad range of harmful activities that may manifest on our platform. Experts think and talk about these issues under one umbrella — human exploitation.\nIn an effort to disrupt and prevent harm, we remove content that facilitates or coordinates the exploitation of humans, including human trafficking. We define human trafficking as the business of depriving someone of liberty for profit. It is the exploitation of humans in order to force them to engagein commercial sex, labor, or other activities against their will. It relies on deception, force and coercion, and degrades humans by depriving them of their freedom while economically or materially benefiting others.\nHuman trafficking is multi-faceted and global; it can affect anyone regardless of age, socioeconomic background, ethnicity, gender, or location. It takes many forms, and any given trafficking situation can involve various stages of development. By the coercive nature of this abuse, victims cannot consent.\nWhile we need to be careful not to conflate human trafficking and smuggling, the two can be related and exhibit overlap. The United Nations defines human smuggling as the procurement or facilitation of illegal entry into a state across international borders. Without necessity for coercion or force, it may still result in the exploitation of vulnerable individuals who are trying to leave their country of origin, often in pursuit of a better life. Human smuggling is a crime against a state, relying on movement, and human trafficking is a crime against a person, relying on exploitation.\nDo not post: Content or exhibit behavior that may lead to human exploitation, which includes any of the following: Sex Trafficking, covering minors and adults; The sale of children for illegal adoption; Orphanage Trafficking and Orphanage Volun-tourism; Forced Marriages; Labor Exploitation (incl. bonded labor); Domestic Servitude; Non-regenerative Organ Trafficking; Forced Criminal Activity (e.g. forced begging, forced drug trafficking); Recruitment of Child Soldiers. Content geared towards the: Recruitment of potential victims through force, fraud, coercion, enticement, deception, blackmail or other non-consensual acts. Facilitation of human exploitation by coordinating, transporting, transferring, harboring or brokering of victims prior or during the exploitation. Exploitation of humans by promoting, depicting, or advocating for it. Content that offers or assists in smuggling of humans.", "pred_label": "__label__POS", "pred_score_pos": 0.7356278896331787}
{"content": "Le Déjeuner sur l'herbe Law aimed at combating illegal speech on the internet, also known as Avia law after its original proponent, Laetitia Avia.\nAt the heart of the Law lie two notice-and-take down mechanisms: the first requires operators of online platforms to remove terrorist content and child pornography within 1 hour from receiving a notification from the competent administrative authority; the second mandates upon operators of online platforms to remove various types of hatred speech within 24 hours from receiving a notice from a user.\nThe Law was adopted despite\nMarc Zuckerberg’s best lobbyingand an opinion from the European Commission, warning France that its provisions might be in breach of Arts. 3, 14 and 15 of the Electronic Commerce Directive.\nThis week, the French Constitutional Court\npartly quashed the Avia law, stating that the notice-and-take down measures envisaged therein jeopardise freedom of expression and of communication in a manner, which is not adequate, necessary or proportionate to the aim pursued.\nNow held unconstitutional, Art. 1 of the Avia law was set to introduce amendments to\nLaw No 2004-575 on confidence to the digital economy(“LNEC”), which transposed into French law the provisions of the Electronic Commerce Directive. As mentioned, according to Art. 1(1) of the Avia law amending Art. 6-1 LNEC, operators of online platforms, such as social media, marketplaces or search engines, would have had to remove terrorist content and child pornography within 1 hour from receiving a notification from the competent administrative authority. In turn, Art. 1(2) would have introduced a new Art. 6-2 in LNEC, whereby operators of online platforms should have removed various types of “manifestly illegal” hatred speech within 24 hours from receiving a relevant notice from a user. Such operators of online platforms are defined with reference to Art. L111-7(I)of the French Consumer Code and would have been targeted regardless of whether they are established in the French territory. At the same time, only the operators with a high number of unique visitors would have fallen under the scope of application of Art. 1 of the Avia law. The exact threshold was expected in an implementing degree but would have inevitably included such social media platforms as YouTube, Facebook or Google.\nFailure to comply with take-down obligations entails criminal and administrative liability. Art. 6 of the Avia law, which remains in place after the Constitutional Court’s decision, increases the maximum criminal fine for individuals from EUR 75 000 to EUR 250 000, in addition to a one-year imprisonment. In turn, Art. 7 of the Avia law, which was recognised as unconstitutional, would have allowed the\nHigh audio-visual council (CSA)to impose an administrative sanction on online platforms that failed to comply with the notice-and-take down obligations. Similarly to amounts found in the GDPR, such sanction could be in the amount of up to 4% of the annual worldwide turnover or EUR 20 million.\nDuring the drafting stage and as mentioned, the European Commission\nissued an opinion, warning the French government that the then bill and the prospective amendments to the LCEN Law, might be in breach of Arts. 3, 14 and 15 of the Electronic Commerce Directive.\nThe Commission brought to the attention of French legislators, first, that the proposed amendments to the required content of a notice would not be compliant with the minimum requirements, as set in the settled case law of the Court of Justice of the European Union. While under\nL’Oréal, C-324/09a notification needs to be sufficiently precise and adequately substantiated, the new mechanism would have not required the notifier to identify the exact location of the relevant content. Indeed, Art. 1bis, to which the Commission referred with this comment and which was at a later stage replaced with more strict conditions, originally required the notifier only to describe the notified content, the reasons for its removal and, “where appropriate”, the URL through which such content may be acceded. Secondly, the safe harbour requirement under Art. 14 requires hosting providers to “act expeditiously” in order to avoid liability. While the exact duration of such expeditious reaction was never defined at the EU level, the European Commission remarked that a requirement to take-down the content within 24 hours, combined with the high level sanction in case of non-compliance and the reduced requirements for notices could have led to “disproportionate burdens for the online platforms and, in certain circumstances, a risk of over-removal and hence negative effects on freedom of expression”, in particular for intermediaries with limited resources. Thirdly, noted the Commission, a “stay-down” obligation, requiring to prevent the redistribution of removed or dereferenced content, would be in conflict with Art. 15(1) of the Electronic Commerce Directive, which prohibits the imposition of general monitoring obligations on the information transmitted or stored by information society service providers. The Commission also invited France to wait until the adoption of the EU Digital Services Act, promoted by the Commission and whose provisions on liability of intermediaries would overlap with the provisions of the Avia Law.\nDespite the criticism from the European Commission, the contested measures were only amended in part, to remove the “stay-down” obligations. The draft law was adopted by the Senate on May 13. Before the Avia Law could be enacted, the French Constitutional Court, seized by 60 senators,\nfoundthat both mechanisms in Art. 1 are unconstitutional and should be removed. Given the difficulties in assessing the manifestly unlawful nature of the content reported within the time limit, the penalty incurred from the first violation and the absence of a specific cause for exemption from liability, the notice-and-take down can only encourage operators of online platforms to withdraw the content notified to them, whether or not manifestly illegal (para. 19 of the decision). Therefore, the mechanism jeopardises freedom of expression and of communication in a manner, which is not adequate, necessary or proportionate to the aim pursued, that is, the protection of human dignity.\nIt remains to be seen whether Emmanuel Macron will enact the remaining parts of the Avia Law that regulate the increase of fines and some minor issues, including the creation of an “Online Hate Observatory”. In all this, the Avia Law might have the fate of the HADOPI law, vividly discussed in the late 2000s: after the “three-strike mechanism”, which allowed to disconnect infringers from the Internet,\nwas removed from the HADOPI, the law’s scope of application became limited to (rarely) imposing low-level fines on copyright infringers. Image credit: Tetiana Nikolayeva\nFrench Constitutional Court (partly) quashes Avia law on notice-and-take down for illegal speech Reviewed by Anastasiia Kyrylenko on Sunday, June 21, 2020 Rating:", "pred_label": "__label__POS", "pred_score_pos": 0.6169185638427734}
{"content": "by Diana Winters\nThe Resnick Center is excited to share the publication of “Setting the Table for Food-Based Pro Bono Opportunities: A Resource Guide for Pro Bono Attorneys,” authored by Tommy Tobin, a member of the Resnick Center’s Advisory Board, and MAZON: A Jewish Response to Hunger. The guide is designed to facilitate connections between attorneys seeking meaningful pro bono work and anti-hunger organizations.\nThe Covid-19 pandemic has exacerbated food insecurity in the United States, and the amount of resources needed to address the crisis is staggering. Attorneys seeking pro bono work can assist with direct client services, legislative research, and policy advocacy, among other things. This guide seeks to describe these opportunities and to assist in forming these partnerships.\nWe are grateful to Tommy Tobin, Mazon, and Perkins Coie LLP for their work on and support of the guide. The guide will be updated periodically.", "pred_label": "__label__POS", "pred_score_pos": 0.9906150698661804}
{"content": "2. Rehydrate with water. Unless you are exercising most of the day, water is all you need to adequately restore your body’s fluids. To add zing, flavor your water with a small amount of lemon or orange juice. 3. Drink a glass of water when you feel tired or hungry. Feelings of fatigue and hunger often mean your body is thirsty. A glass of water can boost your energy and eliminate hunger pains. 4. Eat regularly. If you allow yourself to get overly hungry, you’ll fall into the “see food, eat food” mode, grabbing whatever is in the refrigerator or cupboard. Small, frequent — and nutritious — meals help to manage hunger and prevent overeating. 5. Replace shortening with applesauce. When baking cakes, brownies or muffins, replace oil with equivalent amounts of applesauce. This enhances flavor, locks in moisture and reduces calories.", "pred_label": "__label__POS", "pred_score_pos": 0.8289377093315125}
{"content": "ABOUT THIS BOOK\nBitter cold and constant snow. Polar bears, seals, and killer whales. Victor Frankenstein chasing his monstrous creation across icy terrain in a dogsled. The arctic calls to mind a myriad different images. Consisting of the Arctic Ocean and parts of Canada, the United States, Russia, Greenland, Finland, Norway and Sweden, the arctic possesses a unique ecosystem—temperatures average negative 29 degrees Fahrenheit in winter and rarely rise above freezing in summer—and the indigenous peoples and cultures that live in the region have had to adapt to the harsh weather conditions. As global temperatures rise, the arctic is facing an environmental crisis, with melting glaciers causing grave concern around the world. But for all the renown of this frozen region, the arctic remains far from perfectly understood.\nIn\nA History of the Arctic, award-winning polar historian John McCannon provides an engaging overview of the region that spans from the Stone Age to the present. McCannon discusses polar exploration and science, nation-building, diplomacy, environmental issues, and climate change, and the role indigenous populations have played in the arctic’s story. Chronicling the history of each arctic nation, he details the many failed searches for a Northwest Passage and the territorial claims that hamper use of these waterways. He also explores the resources found in the arctic—oil, natural gas, minerals, fresh water, and fish—and describes the importance they hold as these resources are depleted elsewhere, as well as the challenges we face in extracting them.\nA timely assessment of current diplomatic and environmental realities, as well as the dire risks the region now faces,\nA History of the Arctic is a thoroughly engrossing book on the past—and future—of the top of the world.", "pred_label": "__label__POS", "pred_score_pos": 0.5798330307006836}
{"content": "MAY 12, 2020\nWhile the U.S. continues to practice social distancing, the 2020 presidential election is still underway as we head towards November. This remains a critical time for middle school and high school students to keep learning about the election process, understand the power of their vote and how to vote, and feel compelled to be active participants in our constitutional democracy — even if they must do so from home.\nTo continue to support your teaching of the election, we have released new lessons and tools that can be used with remote learning.\nTo adapt to the current circumstances, many states are exploring safer voting options for their primaries, such as vote-by-mail. Are your students aware of these new practices and what to expect in their state?\nEven if your students won’t be voting in 2020, the presidential election offers a unique moment to pause, discuss, and build important knowledge. To support your conversations, we just released a new lesson plan with a fillable PDF option. It will help students consider the importance of voting, connect with current issues, and decide for themselves if voting is something they will do.\nA candidate has to pass a lot of tests before anyone can actually vote for them for president. Introduce your students to the big events and mile markers of the electoral process with this lesson plan and help them learn what a candidate must do before reaching the final test: the general election.\nLace up your shoes and learn how candidates run the race to become President of the U.S. In this new printable infographic, your students will see who can qualify to run, how they must prepare, and the different hurdles they have to overcome to make it to the finish line: Inauguration Day.\nExplore all of our free election curriculum and teaching resources at our Election Headquarters.", "pred_label": "__label__POS", "pred_score_pos": 0.6891353726387024}
{"content": "We Take Desk Appearance Tickets (DATs) Seriously\nWhen arrested, people are routinely given what is called “desk appearance tickets” or “DATs” for short. A desk appearance ticket is legally the same thing as a formal arrest. Because the police, the district attorney’s office and judges all treat desk appearance tickets seriously, you should too. It is critical that you contact a New York City criminal defense lawyer immediately at any time you are arrested, even if it’s “only” for a DAT.\nOur attorneys at Konta, Georges & Buza, P.C., have handled virtually every type of criminal case both as defenders and prosecutors. Arrange a free consultation by calling 212-710-5166. What Is A DAT?\nAfter arresting and processing a suspect, police do not always feel the need to keep them in central booking. Instead, they will issue a DAT, which gives a date and time for when the arrestee is due in court for their arraignment.\nThere are a few factors that determine whether a defendant will be placed in central booking or given a DAT:\nIf a person is charged with a felony, a domestic violence crime or has a significant criminal record, then they will be kept in central booking until their arraignment. In these cases, the arraignment must happen within 24 hours. Police may give a person a DAT if the crime is a misdemeanor and they believe the person will not miss their court date or run away. In this situation, you can await your arraignment at home.\nDon’t let the use of the word “ticket” fool you. If you were given a DAT, you were placed under arrest, and you could be facing serious penalties, including jail time. You need to start building your defense.\nTake Advantage Of The Time You Have Before Your Arraignment\nIf you or a loved one has been issued a DAT, and if you don’t go to court on the date you were instructed to go, the judge will issue a warrant for your arrest, meaning the police will arrest you on sight. It is extremely important you arrive at court at the specified date.\nThe upside of receiving a DAT is that you have time to find an attorney and start planning for your arraignment. This is a crucial period, as the police will be using this time to gather evidence against you.\nAt Konta, Georges & Buza, P.C., our lawyers have worked on both sides of the aisle. As a result, they are familiar with the strategies that prosecutors use throughout the criminal process. They will use their insight to secure the most favorable results possible for your case.", "pred_label": "__label__POS", "pred_score_pos": 0.6815695762634277}
{"content": "The COVID-19 pandemic remains the number one health concern around the globe as we await approval of multiple vaccines. There are still many unanswered questions and challenges that lie ahead for the biopharma industry, health stakeholders, and government, particularly around development, prioritization, and distribution of the vaccines. Podcast host Bob Coughlin and his guests, Clement Lewin, Head of BARDA Office & New Vaccines at Sanofi Pasteur, and Dr. Kelly Moore, Associate Director of the Immunization Action Coalition & Adjunct Associate Professor at Vanderbilt University Medical Center, discuss these timely issues.", "pred_label": "__label__POS", "pred_score_pos": 0.9201121926307678}
{"content": "Is debate pointless?\nI've posted this question in other place online but never really got a response.\nOver the past few years I've noticed that facts and reality are increasingly meaning less to people. (Well, some people). I felt like no matter how many times I show them the facts it doesn't matter. They hold onto their beliefs political/religious/ whatever, no matter what the evidence may say. Well the other day I had my suspicions confirmed when I heard NPR's Talk of the Nation. They did a story on research being done at the University of Michigan on something called the \"Backfire effect\". Brendan Nyhan and Jason Reifler have found that when someone holds a belief and is then presented with facts that contradict that belief, they are likely to hold onto that belief all the more strongly. In effect, presenting a misinformed person with the correct information only strengthens their belief in the misinformation. The Washington Post did a story on this a while back too.\nSo my question is this: Is there just no point in having a discussion with these people? If reality only makes them hold onto their false beliefs all the more strongly, what's the point? It's a conversation ender. \"Hi, do you know that evolution is a lie?\" \"It's not.\" \"Yes it is!\" \"Wait a second, before I take the time to talk to you about this, would you, if presented with facts that contradict your views, change your mind?\" \"Nope, not in the slightest. It would just confirm my faith.\" \"Uh...have a nice day.\" (And keep in mind, this is not just fundies, the research was done on average people on political issues) If we can't even have a discussion about things where the facts and reality matter, how can we build a stable society? Doesn't everything just come down to either who can get the most people to the polls or who has the most guns?", "pred_label": "__label__POS", "pred_score_pos": 0.637580931186676}
{"content": "x, x<2) thin films doped with erbium have been deposited on silicon substrates by electron cyclotron resonance plasma enhanced chemical vapour deposition (ECR-PECVD). The formation of silicon nanoclusters along with optically active erbium ion complexes during high temperature annealing results in strong erbium photoluminescence near a wavelength of 1.54 μm. A portion of the deposition parameter space for the ECR-PECVD system has been mapped in an attempt to optimize the films for this luminescence. The resulting films ranged in composition from 0% to 22% excess silicon and 0.45% to 3.7% erbium, as determined by Rutherford Backscattering Spectroscopy. The effects of annealing were investigated between 600 oC and 1000 oC under flowing nitrogen gas. The 1.54μm emission was found to be enhanced by the presence of excess silicon, reaching a maximum at ~5-8 atomic % excess and an 800 oC anneal. This result strongly suggests the sensitization of infrared, erbium luminescence by silicon nanoclusters. The films exhibited an additional blueviolet light emission which has also been attributed to the erbium dopant. The visible and infrared luminescence signals were found to occur in inverse proportion to each other with the visible signal decreasing as the amount of silicon excess increases.", "pred_label": "__label__POS", "pred_score_pos": 0.5607478618621826}
{"content": "You may already know that workers' compensation insurance is designed to protect employees who are injured in the workplace. But workers' compensation is generally administered differently from state to state—so what about military workers or private contractors who are stationed outside the U.S., where safety codes and protocol may be different? Read on to learn more about Defense Base Act (DBA) workers' compensation insurance and how it can protect you if you're injured or made ill on the job.\nWhat is DBA Workers' Compensation Insurance?\nDBA insurance is provided to employees of military contractors or subcontractors who are U.S. citizens or legal immigrants, working for a U.S. company, but who are located outside the U.S. Federal law requires all private employers who employ individuals on military bases located outside the U.S. to carry workers' compensation insurance. This requirement also extends to any land or property the U.S. uses for military purposes, including training and housing facilities. Unless a worker has a waiver from the U.S. Department of Labor (DOL), they're required to be covered under a DBA policy, regardless of nationality, age, sex, or a wide range of other criteria.\nDBA workers' compensation insurance does not apply to workers once they return to the U.S. For example, if a DBA-covered employee is performing work for a private military contractor in South Korea, his or her DBA workers' compensation policy will lapse once this employee returns to the U.S. and resumes work for this contractor in his or her home state. Under these circumstances, the contractor would need to obtain a state-sponsored or approved workers' compensation policy to kick in once the employee returned stateside.\nHow Can DBA Workers' Compensation Insurance Protect You?\nThe U.S. has quite a few federal and state government organizations that protect employees' rights and employee working conditions within the United States—from the Occupational Safety and Health Administration (OSHA) to the DOL to the Equal Employment Opportunity Commission (EEOC). All companies that operate within the U.S. must abide by these agencies' laws, rules, and regulations, and non-compliance can be punishable with steep fines or, in some cases, even jail time.\nBut employers who operate outside the U.S. can face a far bigger grey area when it comes to safeguarding employees' rights. While responsible companies will continue to maintain high standards when it comes to on-the-job health and safety, the challenges of trying to maintain safe working conditions outside the U.S. can mean that accidents will happen. By ensuring your employer has DBA workers' compensation insurance, you're guaranteed compensation if you incur medical expenses or miss work due to an on-the-job injury.", "pred_label": "__label__POS", "pred_score_pos": 0.5238080620765686}
{"content": "Stakeholders for scientific data, both publishers and consumers, face many challenges in their routine activities. Consumers require methods to assess whether available data is fit for their usage. Likewise, producers are often expected to justify their efforts in generating new datasets. In both cases, the availability of provenance records for data products can be of valuable aid.\nThe OPeNDAP framework enables web-based access to data in multiple formats and granularities. However, OPeNDAP presently provides limited support to track the steps involved in generating data products. This work aims to extend sections of the present OPeNDAP framework with functionality for logging provenance records, enabling consumers to obtain provenance for OPeNDAP datasets. Additionally, to allow data producers to track how their datasets are used, tracking for how consumers modify and use registered data will be provided.", "pred_label": "__label__POS", "pred_score_pos": 1.0000098943710327}
{"content": "Loading...\nExport citation\nChoose an application\nAbstract\n\"This edited book focuses on the organization and meaning of craft work in contemporary society. It considers the relationship between craft and place and how this enables the construction of a meaningful relationship with objects of production and consumption. The book explores the significance of raw materials, the relationship between the body, the crafted object and the mind, and the importance of skill, knowledge and learning in the making process. Through this, it raises important questions about the role of craft in facing future challenges by challenging the logic of globalized production and consumption. The Organization of Craft Work encompasses international analyses from the United States, France, Italy, Australia, Canada, the UK and Japan involving a diverse range of sectors, including brewing, food and wine production, clothing and shoe making, and perfumery. The book will be of interest to students and academic researchers in organization studies, marketing and consumer behaviour, business ethics, entrepreneurship, sociology of work, human resource management, cultural studies, geography, and fashion and design. In addition, the book will be of interest to practitioners and organizations with an interest in the development and promotion of craft work.\"", "pred_label": "__label__POS", "pred_score_pos": 0.7203797101974487}
{"content": "Ecclesiological contributions of emerging churches for their parent communities View/ Open Date26/11/2013 Author\nStockdale, Todd\nMetadata Abstract\nThis thesis examines the contributions that emerging churches make to their parent communities’ understanding of church. As a work in practical theology, it is focuses on the theology that is deeply embedded within the everyday language, symbols, and practices of ordinary individuals and communities. Thus, the research in this thesis centres on two concrete emerging communities and employs qualitative methods to examine and analyse the actual practices, values, and beliefs of community participants—treating the data generated through the investigation of these emerging churches as theological material. The thesis is structured in six chapters, beginning in chapter one with a preliminary sketch of the wider emerging church phenomenon, a brief account of the researcher’s own earlier experiences with emerging communities, and an initial overview of the research already conducted on emerging church. Following this introduction, the thesis outlines the research methodology in chapter two, taking an approach to practical theology that moves beyond the prevalent models of correlation and recognizes the embodied nature of theology. Identified in this thesis as ‘theology in the vernacular’ or ‘local theologies’, this approach provides a mechanism for bringing two emerging churches into an impactful encounter with their parent communities’ understanding of church. This encounter unfolds through the remaining four chapters of the thesis. Chapter three provides the ecclesial context for this research by outlining the history and development of emerging church, and locating the two emerging communities within that narrative. Chapters four and five offer an in-depth portrayal and analysis of these two communities by depicting their ecclesial contexts and historical development, their weekly patterns, their physical and online spaces, their worship gatherings, the profiles and personal narratives of their participants, and the core practices of these communities. The findings from these separate sites of research are brought together in chapter six, where five key ecclesiological features are drawn from the common patterns present in these emerging churches. These are: (1) the prevalence of an ecclesial eclecticism, (2) the carving out of a space for theological discussion and intellectual enquiry, (3) a resolute fondness for their local cities, (4) the vital nature of the weekly gathering, and (5) a robustly verbal orientation in the worship gatherings. By bringing these five ecclesiological features into an encounter with the parent tradition of these emerging churches in chapter six, the contribution that these emerging churches are making to their parent communities understanding of church is explored. This thesis argues that these emerging communities are offering their parent communities two alternative ways of understanding church. The first is an understanding of church as a space for ecclesial borrowing and blending—which impacts on the formulation of a community’s ecclesial identity. The second is an understanding of church as a space for discussion, enquiry, and doubt—which impacts on the nature of belonging in ecclesial communities.", "pred_label": "__label__POS", "pred_score_pos": 0.9162824749946594}
{"content": "Ensuring that components of a safety system not only work as designed but also operate appropriately in real-world scenarios.\nFor years, automotive engineering teams have worked to comply with the industry standard ISO 26262, uncovering and addressing functional safety (FuSa) hazards such as software bugs and hardware failures. This standard aims to ensure that complex electronics in today’s cars are reliable ― delivering consistent performance over time, with no critical system failures.\nWith the emergence of automated driving and autonomous vehicles comes an even greater safety engineering challenge. What if components ― such as sensors ― are working as designed, but their capabilities are falling short under real-world conditions?\nFor example, a perception algorithm might recognize various types of pedestrians with a high degree of accuracy, but then unexpectedly misidentify a construction worker wearing a yellow reflective vest. Although the vest increases visibility for humans, it might confuse the perception system of an autonomous vehicle, resulting in catastrophic consequences.\nCan sensors identify objects correctly and trigger an appropriate response? Is the specified behavior appropriate in all potential operating conditions?\nNow a new safety standard is on the way to address this challenge. ISO 21448 “Road Vehicles – Safety of the Intended Functionality” (SOTIF) examines whether a needed safety functionality is successfully delivered in the absence of a failure, such as performance limitations of sensors or systems, unexpected changes in the road environment, etc. It enables engineering teams to avoid situations where vehicles are working as designed, but are falling short under real-world scenarios.\nThe types of scenarios that must be solved to achieve ISO 21448 compliance are incredibly complex and can only be identified by bringing safety analysis and simulation together to replicate real-world conditions and predict results in advance.\nWhile this standard is essential for verifying the safe performance of automated driving and autonomous vehicles, it now places a responsibility on engineering teams to navigate this new area of safety analysis quickly and efficiently. Where to begin?\nAnalyzing different aspects of functional safety, defining technical solutions, and demonstrating compliance is key. Ansys medini analyze now includes capabilities for ensuring SOTIF compliance. It is part of an Ansys toolset designed to meet the complex needs of autonomous vehicle design, bringing together modeling, simulation, and analysis.\nTeams can build performance into their designs from the earliest stages ― and verify that performance before vehicles hit the road by:\nFor more information on SOTIF and how to integrate it into an efficient autonomous vehicle engineering workflow, download the white paper.", "pred_label": "__label__POS", "pred_score_pos": 0.780379056930542}
{"content": "Seven of Europe’s less celebrated national teams are wearing football kits funded by a UEFA scheme that recognises the importance of football in inspiring a nation – on and off the field of play.\nFew things inspire national pride like the national team’s football shirt – whether it’s worn by the players on the pitch or fans cheering from afar.\nMost countries’ proudest football moments are synonymous with an iconic football strip worn throughout a successful tournament – France in 1984, Netherlands in 1988, Denmark in 1992 or Spain in 2008 – they are part of footballing folklore.\n“National football teams are a crucial source of national identity,” said UEFA president Aleksander Ceferin. “They often reflect a country’s footballing philosophy and are a catalyst for national unity by bringing together fans from across that country.”\nSmaller national associations\nUEFA’s Kit Assistance Scheme ensures all its member associations have access to kits – both training wear and matchday clothing – that properly reflect their national identity,\n“UEFA’s relationship with its national associations is a cornerstone of European football,” added Ceferin, “we have been delighted to respond to requests from smaller national associations for help in providing new kits for their national teams.”\nSeven European teams will be sporting new kits secured with UEFA funding during the UEFA Nations League matches from October 10-14, 2020.\nWhich nations benefit from the Kit Assistance Scheme?\nSeven teams are supported by the initiative during the 2020-2022 cycle.\nAndorra\nBelarus Cyprus Faroe Islands Liechtenstein Luxembourg San Marino Who makes the kits?\nMacron, based in Bologna, Italy, is the official supplier for the Kit Assistance Scheme in this period. They were selected through a tender process, which emphasised quality, product, range, discount rates, kit customisation, commitment and merchandising opportunities.\nFees are paid by UEFA with no costs for national associations.", "pred_label": "__label__POS", "pred_score_pos": 0.7252641916275024}
{"content": "As consumers’ media habits evolve, they are creating their own “personal prime times”—points of highly concentrated engagement throughout the day, which offer valuable advertising opportunities across a range of content verticals and digital screens. This research, entitled “Personal Prime Time,” demonstrates that brands should no longer expect a single, universal moment of greatest engagement. While audience size might shift between different times of day, every daypart is primed for meaningful consumer connections.\nThe study looks at the consumer journey through the lens of seven diverse content types—Episodic Shows, Music, News, Podcasts, Short Videos, Social Media, and Weather. In each case, the report acknowledges audience density in specific dayparts, but then provides findings to reveal that “traditional reach” metrics miss the consumer perspective on . . .", "pred_label": "__label__POS", "pred_score_pos": 0.969268262386322}
{"content": "Carnot and start-ups, SMEs and mid-caps Carnot strives to deliver effective innovation solutions for start-ups, SMEs and mid-caps in different business sectors Of the 10 200 R&D contracts signed every year between Carnot Institutes and businesses, 4 900 are with start-ups, SMEs and mid-caps. This does not include the numerous collaborative R&D projects involving SMEs in which Carnot plays a key role or non-research related services provided by Carnot teams. The Carnot institutes strive to: provide easier access – for SMEs and mid-caps – to their technological expertise and resources, be in a position to respond to both near-to-market and the upstream needs of businesses wishing to innovate.\nCarnot Institutes with a strong presence in a given economic sector pool their resources to provide businesses with a comprehensive and straightforward partnership and knowledge & technology transfer offering, rounded out by a sector-specific R&D requirements analysis.\nThere is a special focus on providing businesses with easier access to technology platforms. In order to target businesses’ needs in line with market expectations, Carnot Institutes engage in two-way communication with their business partners. A specific focus on 8 business sectors\nCarnot consortiums have focused especially on simplifying access to R&D for micro businesses, SMEs and mid-caps in eight sectors to help them innovate and stay competitive in a world that is changing at an ever increasing pace:\nAeronautics Automobiles Energy Extractive industries and first-stage processing Manufacturing Pharmaceuticals Fashion and luxury goods Sport and wellness\nAnd this approach works because, thanks to the vitality of the Carnot Institutes engaged in R&D initiatives for micro businesses, SMEs and mid-caps in these eight sectors, the volume of contracts between 2015 and 2019 grew by 85%. For all sectors combined, the network’s activities with micro businesses, SMEs and mid-caps grew 38% over the same period.\nThese results are a reflection of the remarkable collective initiatives spearheaded by each consortium:\nCarnot’s offering is structured and targeted based on analyses of the key challenges facing businesses in these sectors, tech platforms are selected and then made more accessible for businesses by offering them services tailored to their needs,\nchargés d’affairesorganised within a network who go out looking for business. This proactive approach, coupled with two-way communication, an in-depth, context-specific analysis of company needs and a collective R&D offering tailored to each sector, enables Carnot Institutes in each consortium to provide customised solutions for each request. This gives businesses access to Carnot’s top specialists who are brought in to support their innovation projects, demonstrators are specially designed to show what R&D can bring to businesses’ innovations in these sectors. They are part of a broader Proof of Concept-type strategy that locks the contribution of the R&D initiative into its innovation project.\nThis has enabled many companies – some of which had never previously had any contact with the world of research – to finalise their short, medium and even long-term innovation projects. This R&D offering is rounded out by training courses and all of these initiatives are supported by the French Government’s Investissements d’avenir (Investments in the future) programme.", "pred_label": "__label__POS", "pred_score_pos": 0.6843299269676208}
{"content": "Does your project team gel well? If not, can you really achieve success? Project success is tough to achieve as complex scope needs to be completed within compressed schedules and tight budgets. Another major challenge is the heterogeneous mix of project teams in terms of Age, Geography, Culture, Ethical outlook, etc. Ignoring cultural differences in teams is a recipe for disaster. Effective Project Leadership demands investing time in deeply understanding cultural factors, clear communication and complete transparency.This engaging webinar will help you understand key challenges, and walk you through a proven, practical six-step approach used across four continents to lead project teams to success.\n1 items found\nADVERTISEMENT", "pred_label": "__label__POS", "pred_score_pos": 0.9980448484420776}
{"content": "Known as as shajan in hindi drumsticks are loaded with valuable minerals healthy proteins and essential minerals making it a healthy food. A must-have ingredient in sambar one can harness its health benefits in numerous ways such as cooking it with other vegetables lentils (dals) or in the form of soup. Being high in nutrients and tasty in nature here are eight reasons you should include drumsticks in your diet. #1 It builds strong bones Being high in calcium iron and other vitamins drumsticks help in strengthening bones. When consumed either in the form of a juice or with milk", "pred_label": "__label__POS", "pred_score_pos": 0.536880373954773}
{"content": "At TwinThread, we've deployed solutions on thousands of lines, and like you, we've been doing this for a long time. We've thought it through and what's needed is a platform that learns and grows with you.\nUsing TwinThread’s platform, you are guaranteed results and should expect to see a 10x return on investment with no upfront costs - ensuring a no-risk experience. Here are just a few of the actual results our no-risk pilot projects have produced:\n$40 million in potential energy savings.\n60% reduction in repair cycles.\n90% reduction in callbacks.\n50% improvement in customer retention.\n10% improvement in uptime.\n10% reduction in utilities costs.\nAnnual cost savings in the millions.\nSpecifically, we were able to help an F&B manufacturer reduce their testing time by 75% while also improving quality and facilitating greater yield. Here's how we did it. The company's vision was to deliver premium quality products with minimum production waste. They believed that if they could predict quality more accurately during production, they could adjust the manufacturing process in real-time to ensure quality specifications were continuously being met.\nBy placing our Predictive Operations Platform in the hands of their in-house experts, they were able to quickly identify, in real-time, opportunities to further hone in their production assets and accompanying processes to achieve the control over quality and throughput that they were looking for. This resulted in significant reductions in waste and greater confidence in the constant ability to replicate and scale the processes that produced this high quality standard.\nWe have a record of producing significant results in industrial operations and we’re certain, with our Predictive Operations Platform, your domain experts will experience the same. That’s why weguarantee results.\nTo explore other scenarios where TwinThread has had a significant impact,click here.", "pred_label": "__label__POS", "pred_score_pos": 0.9166251420974731}
{"content": "Here, we describe an integrated bioinformatics, functional analysis, and translational pathology approach to identify novel miRNAs involved in breast cancer progression. Coinertia analysis (CIA) was used to combine a database of predicted miRNA target sites and gene expression data. Using two independent breast cancer cohorts, CIA was combined with correspondence analysis and between group analysis to produce a ranked list of miRNAs associated with disease progression. Ectopic expression studies were carried out in MCF7 cells and miRNA expression evaluated in two additional cohorts of patients with breast cancer by in situ hybridization on tissue microarrays. CIA identified miR-187 as a key miRNA associated with poor outcome in breast cancer. Ectopic expression of miR-187 in breast cancer cells resulted in a more aggressive phenotype. In a test cohort (n = 117), high expression of miR-187 was associated with a trend toward reduced breast cancer-specific survival (BCSS; P = 0.058), and a significant association with reduced BCSS in lymph node-positive patients (P = 0.036). In a validation cohort (n = 470), high miR-187 was significantly associated with reduced BCSS in the entire cohort (P = 0.021) and in lymph node-positive patients (P = 0.012). Multivariate Cox regression analysis revealed that miR-187 is an independent prognostic factor in both cohorts [cohort 1: HR, 7.37; 95% confidence interval (CI), 2.05-26.51; P = 0.002; cohort 2: HR, 2.80; 95% CI, 1.52-5.16; P = 0.001] and in lymph node-positive patients in both cohorts (cohort 1: HR, 13.74; 95% CI, 2.62-72.03; P = 0.002; cohort 2: HR, 2.77; 95% CI, 1.32-5.81; P = 0.007). miR-187 expression in breast cancer leads to a more aggressive, invasive phenotype and acts as an independent predictor of outcome.\nIreland ->\nUniversity College Dublin ->\nPubMed", "pred_label": "__label__POS", "pred_score_pos": 0.5839954614639282}
{"content": "Strategies for Eliminating the Achievement Gap\nAs an online Capella University student I am just beginning my new course, Strategies for Eliminating the Achievement Gap, as I advance toward earning a Masters in Education, specializing in educational leadership. The course addresses differences in student achievement due to cultural, gender, racial, social, and economic factors. The course examines current research and best practices with a focus on identifying those practices and instructional strategies most likely to eliminate achievement disparities.\nMy long-term goal is to develop an education model for a school that\n1) is a high quality, effective, and productive learning community, where learning for all students truly is the top priority 2) is free of racism, discrimination, and inequity in any form 3) where a cross-functional, collaborative and engaging partnership exists between school board members, administrators, teachers, students, parents, and the larger community.", "pred_label": "__label__POS", "pred_score_pos": 0.9874678254127502}
{"content": "Tax implications of equity-based compensation\n$225.00\nDescription\nAbstract: Equity-based compensation is a powerful tool for attracting, retaining and motivating executives and other employees. By rewarding recipients for their contributions to a business’s success, it aligns their interests with those of the company and provides them with an incentive to stay. This article explores several equity-based compensation options. A sidebar explains how companies that aren’t prepared to share equity with employees can still enjoy the benefits of equity-based compensation.", "pred_label": "__label__POS", "pred_score_pos": 0.9993926882743835}
{"content": "Insights into the kinetics of thermally induced crystallization of amorphous calcium phosphate\nAuthorized Users Only\n2018 AuthorsUskoković, Vuk\nMarković, Smilja\nVeselinović, Ljiljana\nŠkapin, Srečo Davor\nIgnjatović, Nenad\nUskoković, Dragan\nArticle (Published version) MetadataShow full item record Abstract\nTransformations between amorphous and crystalline apatite mechanistically govern some of the most essential processes in bone metabolism, including biomineralization and bone remodeling. Fundamental understanding of this phase transition can help us gain control over the formation and dissolution of boney tissues in vivo and utilize that knowledge for various therapeutic ends. Crystallization of hydroxyapatite (HAp) and two tricalcium phosphate (TCP) polymorphs from the metastable precursor, amorphous calcium phosphate (ACP) was here studied kinetically and mechanistically using thermal analyses, X-ray diffraction and Fourier-transform infrared spectroscopy. Crystallization was detected in the differential thermal analysis as the exothermic peak at 639.5 °C at the slowest heating regimen of 5 °C min−1, while a combination of different kinetics models, including Augis–Bennett, Borchardt–Daniels, Johnson–Mehl–Avrami, Kissinger, Ozawa and Piloyan, yielded activation energies in the 435–45...0 kJ mol−1 range. Dehydrated ACP required a significant energy input to transform to HAp, thus indirectly proving the key role that structural water plays in this process in a biological setting. The phase transformation at high temperatures involved preformed nuclei and was solely due to their 3D growth, contrasting the edge-controlled nucleation derived earlier as the mechanism of growth in the solution. Crystallization was in both cases accompanied by the formation of needle-shape crystals of HAp through aggregation of ultrafine spherical units of ACP. Relationship between crystallinity and the heating rate was detected only for the initially amorphous structure, indicating a more intense and coherent lattice ordering process in annealed ACP than in HAp. Despite that, crystallization disobeyed the rule of inverse proportionality between the thermal energy required for the relaxation of defects and the level of strain, as the recovery rate of the initially poorly crystalline HAp was higher than that of ACP.\nSource:Physical Chemistry Chemical Physics, 2018, 20, 29221-29235 Publisher: Royal Society of Chemistry (RSC) Projects: United States National Institutes of Health (NIH) / National Institute of Dental and Craniofacial Research (NIDCR), Grant K99-DE021416 Molecular designing of nanoparticles with controlled morphological and physicochemical characteristics and functional materials based on them (RS-45004) Note: Peer-reviewed manuscript: http://dais.sanu.ac.rs/123456789/4514\nDOI: 10.1039/C8CP06460A\nISSN: 1463-9076; 1463-9084\nWoS: 000453935400022 Scopus: 2-s2.0-85057266300 [ Google Scholar ]", "pred_label": "__label__POS", "pred_score_pos": 0.7622253894805908}
{"content": "Dangers in Propane Gas Appliances\nMany homeowners use propane gas in areas where natural gas or electricity are costly, unavailable or inefficient for powering certain appliances. The gas can be used in furnaces to heat the home as well as in other appliances. Defects in the appliance, storage tank or gas supply line, however, may cause a life-threatening safety hazard.\nLeaks\nDamage to the propane storage tank, a loose connection or damage to the propane gas line to the appliance could result in a gas leak. Unlike natural gas, propane gas is odorless and difficult to detect if it leaks. The propane displaces oxygen in the air, which can result in life-threatening symptoms, including loss of consciousness and asphyxiation. To detect a gas leak, listen for hissing from the pipes, use a soapy water solution to check the pipe seams or look for dead vegetation along where the propane line runs from the tank to the house.\nIncomplete Combustion\nA malfunction in the appliance using propane gas could result in incomplete combustion of the gas. Incomplete gas combustion may result in the release of carbon monoxide, which is a deadly poison. Signs of incomplete gas combustion include improper flame color in appliances such as a stove or water heater or the presence of soot in heating appliances.\nReferences\nWriter Bio\nJessica Lietz has been writing about health-related topics since 2009. She has several years of experience in genetics research, survey design, analysis and epidemiology, working on both infectious and chronic diseases. Lietz holds a Master of Public Health in epidemiology from The Ohio State University.", "pred_label": "__label__POS", "pred_score_pos": 0.7008320093154907}
{"content": "How to Remove Tire Marks Off Epoxy Flooring\nEpoxy flooring, often used in garages and industrial settings, consists of epoxy resins that coat and protect the floor. Durable epoxy flooring provides a waterproof barrier, resists chemicals, mold and oil, and requires little maintenance to keep it clean. Pulling in or backing out of the garage too quickly, however, can leave tire marks on your epoxy floor. These marks need a stronger method of cleaning than mopping alone to remove them completely, but don't always require the use of harsh chemicals.\n1\nMix 1 gallon of warm water with about 2 tablespoons of dish detergent and apply it to the tire marks. Allow it to sit for at three to five minutes. Alternatively, put on rubber gloves and pour or spray enough citrus solvent on the tire marks to cover them completely.\n2\nScrub the marks with a melamine sponge to remove them from the epoxy floor. If you used citrus solvent, scrub the floor with a firm-bristled brush.\n3\nMop the floor with clean water in a bucket to remove any cleaning residue and allow it to dry.\nReferences\nWarnings\nDon't use solvents near open flames or while smoking. Avoid touching solvents. They can cause skin and eye irritation.\nWriter Bio\nMelissa Rae has been a writer since 2008, specializing in home-and-garden, business, technology and education topics. Rae holds a Bachelor of Science in business administration from Herzing University.", "pred_label": "__label__POS", "pred_score_pos": 0.970533013343811}
{"content": "According to the World Health Organisation, Coronaviruses are a large family of viruses causing illnesses, ranging from common colds to more severe diseases. Coronaviruses can be transmitted between animals and humans.\nCommon symptoms of infection include respiratory issues, fever, cough and shortness of breath. In more severe cases these can symptoms can cause pneumonia, severe acute respiratory syndrome, kidney failure and even death.\nStandard procedures recommended to prevent the spread of Coronavirus include but are not limited to the following:\nWashing of hands regularly with an alcohol based hand rub or with soap and water. Maintaining at least a 1-metre distance between yourself and anyone who is coughing or sneezing. This is because when individuals cough or sneeze, small liquid droplets are sprayed from the nose and mouth, which may contain viruses. If you are too close, these droplets including the Coronavirus can be breathed in, provided the individual who is coughing has the virus. Avoid touching the eyes, mouth and nose. This is because many surfaces can pick up the virus and once contaminated the virus hands can transfer the virus to the eyes mouth and nose. This in turn, can enter the body and make you sick. Make sure the people around you as well as yourself follow good respiratory hygiene. This involves covering your mouth and nose when you sneeze or cough with a belt elbow or tissue. Ensure the tissue is disposed of immediately. Again, the reason for this is droplets emitted can potentially spread the virus if an infected person sneezes. If you feel unwell, stay at home. If you have fever, cough and difficulty breathing, seek medical attention and call in advance. Keep up to do date with the Coronavirus hotspots and if possible avoid travelling to these places, especially if you are an older person or have diabetes, heart or lung disease.", "pred_label": "__label__POS", "pred_score_pos": 0.6357959508895874}
{"content": "Seagreens Food Capsules - 60 caps\nFulfil your daily nutritional needs with these easy to take vegan capsules.\nTake two capsules per day to maintain and build the foundation of your health, or more to tackle specific health conditions or undertake a detoxification programme.\nThis unique blend of three sustainably-harvested shallow water seaweeds (Ascophyllum nodosum, Pelvetia canaliculata, and Fucus spiralis) has been specifically combined to provide an exceptionally broad nutritional profile.\nSeagreens Food Capsules contain all the micronutrients which we need even in tiny amounts, to feed the foundation of health on a permanent daily basis.\nThey provide a rich nutrient source of vitamins, minerals, essential fatty acids and trace elements in a natural, synergistic combination which your body recognises as food and can therefore absorb completely.\nSeagreens adds missing nutrients to your diet, helps you absorb more nutrients from other foods you eat and have a gentle detoxifying action helping you expel toxins, including heavy metals from the body.\nSeagreens Food Capsules can be taken by everybody, including during pregnancy. They are suitable for babies, children and elderly people and do not interfere with any other medicines or supplements taken.\nIngredients: 1 Gram (2 Capsules) provides - Protein 75mg • Carbohydrate / Fibre 600mg (of which the non-starch polysaccharides Algin, Fucose, Fucoidan, Mannitol, Methylpentosans, Laminarin, Mannuronic acid 270mg) and essential fatty acids (EFA's) and chlorophyll.\nVitamins - A (antioxidant carotenoids beta carotene, fucoxanthin and violaxanthin) 178µg, B group (including Folic and Folinic acid, Thiamine, Riboflavin, Niacin, Pantothenic acid, Pyridoxin, Choline and Cobalamin) 8.9µg, C (antioxidant) 1.25mg, D (Cholecalciferol) 0.01µg, E (antioxidant) 0.23mg, H (Biotin) 0.30µg and K (Menadione) 10µg\nMinerals - Calcium 20mg, Chlorine 35mg, Magnesium 7mg, Nitrogen 10.5mg, Phosphorus 1.5mg, Potassium 25mg, Sodium 35mg, Sulphur 30mg\nTrace Elements - Antimony trace, Boron 0.06mg, Cobalt 5.4µg, Copper trace, Fluorine 0.2mg, Germanium trace, Gold trace, Iodine 442µg, Iridium trace, Iron 575µg, Lithium trace, Manganese 0.03mg, Molybdenum 0.65µg, Platinum trace, Rubidium trace, Selenium 0.15µg, Silicon 1mg, Silver trace, Tellurium trace, Titanium trace, Vanadium 2.3µg and Zinc 0.13mg\nAmino Acids - Histidine trace, Isoleucine 0.53mg, Leucine 5.3mg, Lysine 2.78mg, Methionine 0.68mg, Phenylalanine 0.83mg, Threonine 2.33mg, Tryptophan trace, Valine 2.63mg, Alanine 4.57mg, Arginine 11.17mg, Aspartic acid 4.88mg, Cysteine 0.90mg, Glutamic acid 5.18mg, Glycine 3.90mg, Proline 3mg, Serine 2.25mg, Tyrosine 1.05mg\nBetaines - Glycine Betaine trace, Gamma Amino Butyric Acid Betaine trace, Delta Amino Valeric Acid Betaine trace, TML (Laminine) trace, L-Carnitine trace, Trigonelline trace; enzymes, lipids, lipoproteins & many compounds which cannot be 'formulated'.", "pred_label": "__label__POS", "pred_score_pos": 0.7273780107498169}
{"content": "In August 2020, on Sunday, amid the covid crisis, to spread positivity and love, India gifts Nepal 10 ventilators of Rs. 28 million worth considering it as an urgent need. With an aim to enhance the fragile relations between the two nations, India displayed a great gesture of kindness and humbleness.\nThe Covid-19 pandemic that has been a growing threat for many nations, and has consumed nearly one-fourth of the Earth’s population. In such difficult times, it was wise enough to forget the tensions between the nations and work collectively to combat this virus. The humanitarian approach directed towards the other nation sets an example of how other nations should work as a united body.\nAccording to the Indian Embassy, “These 10 advanced ventilators are broadly designed to support various invasive and non-invasive respiratory systems. Providing a range of applications, these ICU ventilators will support the caretaking in the hospitals. Due to their handy nature, they can be portable and will be proving a helping hand to the hospitals.” Further stating, “The Indian army has always supported the Nepal army as directing the value of humanity and respect towards them. However, gifting 10 ICU ventilators is just the part of the same humanity and respect that both nations follow.”\nThe conflict existing between India and Nepal is over the land dispute issue which has been pertaining for a long time. As military tensions have been an issue of interest for China and India, Nepal is furious regarding the leniency India is displaying over the land dispute. Earlier, India and Chinese soldiers were witnessed physically fighting on Galwan Valley border.\nAs a result, India deployed its soldiers at Kalapani area which lies west to Nepal where the borders of the three nations meet. Therefore, Nepal repeatedly argues, Kalapani area lays under their country. However, India remains focused on China while Nepal is sidelined. Eventually, India has provided aid to Nepal while keeping aside their conflicts.\nRecent ceremony held at Health Ministry of Nepal, India Ambassador, Vinay Mohan Kwatra delivered 10 ICU ventilators to Health Minister Bhanu Bhakta Dhakal. Impressed by the gesture, Mr Dhakal thanked the Indian government for their kind gesture towards Nepal. He stated in times like these, despite the troubling past, India has been grateful enough gift them ICU ventilators.\nWhile addressing the nation he said, “Indian government under the leadership of Prime Minister Narendra Modi has decided to hand over 10 ICU ventilators to enhance their relationship with Nepal.” At last, Mr Dhakal restated India as “Gaashkatayara” which in Nepali means sacrificing for the welfare of others.\nEven though on April 22, India provided Hydroxychloroquine for treating the covid patients. Additionally, on September 15, India gifted 2, 000 Remdesivir vials to Nepal. In Nepal, around 1,00,000 covid cases have been registered. While many lives are at stake, it will be advisable for the citizens to stay protected from this deadly virus. To conclude, we can hope good relations will continue with Nepal and this pandemic may soon get over because it is the worst of times that the world has faced so far.", "pred_label": "__label__POS", "pred_score_pos": 0.9876713752746582}
{"content": "Abstract\nNF-κB repressing factor (NRF), a nuclear inhibitor of NF-κB, is constitutively expressed and is implicated in the basal silencing of specific NF-κB targeting genes, including IFN-β, IL-8/CXCL8, and iNOS. Little is known about the regulation of NRF and its role in response to stimuli. Airway smooth muscle (ASM) is a rich source of inflammatory mediators that may regulate the development and progression of airway inflammation. We have previously reported that NE activates NF-κB in primary human ASM (hASM), leading to induction of TGF-β1. In this study, we describe that, instead of inducing the NF-κB response gene IL-8/CXCL8, NE suppressed IL-8/CXCL8 release and mRNA expression in hASM cells. Transcriptional blockade studies using actinomycin D revealed a similar degradation rate of IL-8/CXCL8 mRNA in the presence or absence of NE, suggesting an involvement at the transcription level. Mechanistically, the NE repressive effect was mediated by inducing NRF, as shown by RT-PCR and Western blotting, which was subsequently recruited to the native IL-8/CXCL8 promoter leading to removal of RNA polymerase II from the promoter, as demonstrated by chromatin immunoprecipitation assays. Knockdown of NRF by small interfering RNA prevented NE-induced suppression of IL-8/CXCL8 expression. In contrast, NE did not induce NRF expression in A549 and Beas-2B cells, where NE only stimulates NF-κB activation and IL-8/CXCL8 induction. Forced expression of NRF in A549 cells by an NRF expression plasmid suppressed IL-8/CXCL8 expression. Hence, we describe a novel negative regulatory mechanism of NE-induced NRF, which is restricted to hASM and mediates the suppression of IL-8/CXCL8 expression.\nASJC Scopus subject areas Immunology Medicine(all)", "pred_label": "__label__POS", "pred_score_pos": 0.9481266736984253}
{"content": "Rather than processing water, many intercoolers process air and act as a radiator to remove heat. As cold air passes through your intercooler and into the turbocharger, more oxygen is carried which allows the engine to burn more fuel - resulting in more power. An efficient intercooler system can result in 5%-10% more power, and resists heat soak for longer. All cars with turbocharged engines will benefit from a quality intercooler, which allows the engine to combust more air and fuel per cycle. While your intercooler offers more power, it will also play a huge role in reducing wear, prolonging life and ensuring a smooth running turbocharged engine. Before fitting an intercooler, you should be aware that like all essential car components, they do wear out with time, with leaks being a common sign that your intercooler needs replacing or repairing.When it comes to replacing, repairing or upgrading your turbocharger, finding the correct product that suits your vehicle is key. And that’s why at Halfords we offer a vehicle registration tool that pulls relevant intercoolers to suit your vehicle. All you have to do is enter your registration number and our database will pull the relevant products in seconds. Within our range, you’ll car intercoolers for all car makes and models. For a safe and professional fitting service, head down to your local Autocentres local Autocentres\ntoday.", "pred_label": "__label__POS", "pred_score_pos": 0.5018190145492554}
{"content": "Black people are in pain, in danger, and dying at disproportionate rates due to systemic racism in our country. There's no longer a place for being \"not racist\" - it's time to become anti-racist. Here's what we've been doing to take action, and steps you can take to support the Black Lives Matter movement.\nWe've all likely experienced bumps in the road during the recent dual pandemics: Coronavirus and systemic racism. Our routines are thrown off, competitions are canceled, it's difficult to make decisions, and we're generally feeling depleted. When you're having a rough moment, much like you'd call Roadside Assistance on a road trip, AAA can help: that is, engaging in Awareness, Acceptance, and Action.\nWith a constant news cycle, practice and competition cancellations, and work and school being shifted online, everyone is experiencing the impact of the COVID-19 pandemic. We wanted to provide a few updates and resources. Please let us know how we can help you and your family during this time.\nHow do I become more confident as a runner? Confidence is not something you either have or you don't. Learn how to build your belief in your abilities over time through your training to leverage on race day.\nShort course is over and the results are in! Regardless of how your season went, reflect on key questions to take ownership of your swimming, keep yourself accountable, and bring intention to your future training.\nMarathons are all about respecting the distance - while learning proper form, creating a training plan, knowing techniques to stave off injury, and staying disciplined for months. Here are some tips to tackle 26.2!\nWe often talk to parents who need someone to help their child with the mental game, but they don't know where to begin or what questions to ask. Here's what parents should know about sport psychology and mental skills training.", "pred_label": "__label__POS", "pred_score_pos": 0.7257999181747437}
{"content": "The U.S. Department of Transportation (U.S. DOT) published a Notice of Funding Opportunity (NOFO) to apply for $1 billion in Fiscal Year (FY) 2020 discretionary grant funding through the Better Utilizing Investments to Leverage Development (BUILD) Transportation Discretionary Grants program.\nFY 2020 BUILD Transportation grants are for planning and capital investments in surface transportation infrastructure and are to be awarded on a competitive basis for projects that will have a significant local or regional impact. BUILD funding can support roads, bridges, transit, rail, ports, or intermodal transportation.\nProjects for BUILD will be evaluated based on merit criteria that include safety, economic competitiveness, quality of life, environmental sustainability, state of good repair, innovation, and partnership.\nTo better address the needs of rural America, which has historically been neglected, U.S. DOT intends to award 50% of BUILD Transportation grant funding to projects located in rural areas that deliver positive benefits for these communities, consistent with the department’s R.O.U.T.E.S. initiative. For this round of BUILD Transportation grants, the maximum grant award is $25 million, and no more than $100 million can be awarded to a single state, as specified in the appropriations act.\nTo provide technical assistance to prospective applicants, the U.S. DOT is hosting a series of webinars during the FY 2020 BUILD grant application process. A webinar on how to compete for BUILD Transportation Grants for all applicants will be held on February 25. Further details will be made available here, with the deadline to apply May 18.", "pred_label": "__label__POS", "pred_score_pos": 0.7660495042800903}
{"content": "Deputy Prime Minister and Finance Minister Heng Swee Keat delivered his Budget 2020 statement on 18 February 2020. In his speech, he announced some of the ways SSG and WSG will be helping both individuals and enterprises as part of Singapore’s response to the challenges in the new decade.\nEnhanced Support under the Adapt and Grow Initiative\nAs part of the Stabilisation and Support Package, sectors directly affected by COVID-19 will get additional support. The affected sectors are: tourism, aviation, retail, food services. These sectors will receive support through\nThe funding period for reskilling in these sectors will be extended from three months to a maximum of six months.\nNext Bound of SkillsFuture\nThe Next Bound of SkillsFuture aims to further support Singaporeans to develop to their fullest potential throughout life, regardless of their starting points. The Next Bound of SkillsFuture will (1) enable individuals to continue learning, (2) enhance the role of enterprises in developing their workforce, and (3) have a special focus for mid-career workers through a new SkillsFuture Mid-Career Support Package for locals in their 40s and 50s, to help them stay employable and move to new jobs or new roles.\nMore details will be released during the Committee of Supply (COS) debate.", "pred_label": "__label__POS", "pred_score_pos": 0.6780800223350525}
{"content": "Energy powers the economy and illuminates the society. Therefore, it is an essential requirement for socio-economic development. In our role as a petroleum marketing and distribution company, we are a stakeholder in the advancement agenda of the Nigerian nation.\nBy this, we recognize the need to sustain the supply of the critical resources depended upon by the different categories\nof players in the country's economic space to propel the desired growth. Thus, we responsibly and transparently manage our allocations to ensure that petroleum products are available at our stations across the country.", "pred_label": "__label__POS", "pred_score_pos": 0.9715080261230469}
{"content": "Performance of sewage treatment plant with septic tank, anaerobic filter and constructed wetland with Typha spp Abstract\nThe study reports the performance of a sanitary effluent treatment constituted by a septic tank, anaerobic filter and constructed wetland. The study monitored nutrient’s, carbonaceous material’s and thermotolerant coliform’s (CT) removal efficiency during 12 months. The treatment system included a septic tank, an anaerobic filter and a horizontal subsurface flow constructed wetland cultivated with\nTypha spp. Effluent samples were monthly collected before and after the septic tank, anaerobic filter and wetland. The removal efficiency for N-NH + 4 was 37.6%, 66.3% for total P, 37% for COD, 54% for BOD and 99.4% for CT. The anaerobic filter and wetland were more efficient than the septic tank. P-total reduction was higher in the constructed wetland than in the anaerobic filter. Climatic conditions influenced the evaluated constituent’s removal being the highest values during hot months. Keywords\nDOI: http://dx.doi.org/10.4136/ambi-agua.2305\nRevista Ambiente & Água. ISSN:\n1980-993X DOI: 10.4136/1980-993X\nEditoração: Apoio: Filiada à ABEC:", "pred_label": "__label__POS", "pred_score_pos": 0.673446536064148}
{"content": "Art collecting creates an emotional experience that takes into account the monetary value of each individual piece. Collectors are lured into a work through its impassioned appeal, but what finalizes this addition to their collection is the financial worth. Emotion and finance appear opposite to one another, but collectors consider both when admiring new art such as limited edition prints. This is the emotional and monetary value seen through the eyes of an art collector.\nFuel the Soul and Fit the BudgetArt fills a person’s soul and environment with a specific energy. Every collector knows what energy feels right to them. When they first see a work that embodies this energy, they sense a calling from it. However, this energy can shift drastically due to financial reasons such as a limited budget. Art collecting requires harmony between emotional connection and financial responsibility. Collectors prioritize this balance because they crave the fulfillment that results from satisfying their souls and wallets. Limited edition prints are an excellent example for art that suits the type of connection and price collectors search for. The Value of Art is Not Carved in StoneThe value of an artwork is not carved in stone. Instead, the value ages over time like a fine wine. As time passes, the value of art increases. This value applies on both the emotional and financial side. After a collector adds a piece to their collection, that piece’s worth begins to grow. Over the years, its monetary value starts to slowly increase. For the emotional value, that connection never ceases and only blossoms. Even after its original owner passes, that artwork will be given to someone who feels a similar or stronger attachment. Returning to the earlier example of limited edition prints, each one of created with a one-of-a-kind design. Their designs are what welcomes the collector’s attention along with their price. No matter how many prints are created, every single one of them holds an exclusive feature that increases their value over time.", "pred_label": "__label__POS", "pred_score_pos": 0.9157339930534363}
{"content": "The U.S. Department of Transportation has issued an Enforcement Notice clarifying, in the context of the 2019 Novel Coronavirus (COVID-19) public health emergency, that US and foreign airlines remain obligated to provide a prompt refund to passengers for flights to, within, or from the United States when the carrier cancels the passenger’s scheduled flight or makes a significant schedule change and the passenger chooses not to accept the alternative offered by the carrier.\nThe obligation of airlines to provide refunds, including the ticket price and any optional fee charged for services a passenger is unable to use, does not cease when the flight disruptions are outside of the carrier’s control (e.g., a result of government restrictions).\nThe Department is receiving an increasing number of complaints and inquiries from ticketed passengers, including many with non-refundable tickets, who describe having been denied refunds for flights that were canceled or significantly delayed.\nIn many of these cases, the passengers stated that the carrier informed them that they would receive vouchers or credits for future travel.\nBecause the COVID-19 public health emergency has had an unprecedented impact on air travel, DOT’s Aviation Enforcement Office will exercise its enforcement discretion and provide carriers with an opportunity to become compliant before taking further action. However, the Aviation Enforcement Office will monitor airlines’ refund policies and practices and take enforcement action as necessary.", "pred_label": "__label__POS", "pred_score_pos": 0.9451590776443481}
{"content": "Students with varying educational and medical diagnoses often have difficulty in executive functioning skills. These skills (planning, organizing, executing, initiating, emotional regulation, attention/memory, etc) are foundational skills to access academics and cognition. Any deficits or weaknesses in EF ultimately impact classroom performance and skill acquisition. This session will serve as an interactive workshop with a brief education on EF support with compensatory external strategies to improve student independent and classroom experience. Participants will leave the session with the physical tools needed for immediate implementation upon returning to their classrooms. Participants will also gain a better understanding of how to include executive functioning in IEP goals, including progress monitoring methods.", "pred_label": "__label__POS", "pred_score_pos": 0.9994547367095947}
{"content": "As high-performance CPUs shrink into advanced CMOS process technologies, thinning dielectrics and dwindling wire interconnects demand an ever-increasing complexity of reliability analysis, modeling, and design techniques. This is particularly true for CPUs in notebook and desktop computers, in which to maximize the user experience, it is critical to maximize the voltage and frequency for the small fraction of the lifetime when peak performance is actually needed. An overview of methodologies and design considerations for maintaining the silicon reliability of high-performance CPUs is presented, with particular focus on dielectric breakdown and electromigration as the two most critical limiters. As dynamic voltage and frequency scaling has become pervasive in the mobile and embedded processor space, these techniques will become essential to a broader spectrum of the semiconductor industry as their respective frequencies continue to increase.\nBio:\nTom Burd received his B.S., M.S., and Ph.D. degrees in Electrical Engineering & Computer Science from U.C. Berkeley in 1992, 1994, and 2001, respectively. He joined AMD in 2005, and is currently the physical design architect of a next-generation x86 CPU core. Previously, Dr. Burd has held various technical leadership roles on multiple high-performance x86 microprocessors, including technical leadership for the silicon reliability of several generations of CPU & APU products. Prior to joining AMD, he consulted at several Silicon Valley startups, including Telegent Systems, Raza Microelectronics, and Matrix Semiconductor.", "pred_label": "__label__POS", "pred_score_pos": 0.5355445742607117}
{"content": "Florida Health Departments Praised For Innovation\nDespite rising hepatitis A rates, Florida public-health programs have been lauded by a national group.\nThirteen Florida county health departments were included in the National Association of County and City Health Officials’ list of winners for innovative public health programs.\nThe Pinellas County Health Department was recognized for the “HPV Ambassador Program” which aims to increase vaccinations to prevent the sexually transmitted human papillomavirus. The Hillsborough County Health Department was recognized for initiatives to address obesity.\nIn all, 53 health departments across the nation were recognized for developing effective programs that can be replicated in other areas. The recognition for the Florida health departments comes as the state grapples with a growing number of hepatitis A cases.\nAs of the end of April, 989 hepatitis A cases had been reported in Florida. According to the state, 96 percent of the people infected had not received the hepatitis A vaccine.\nHepatitis A is a communicable disease usually transmitted person-to-person through ingesting fecal matter through such things as contaminated food or water.", "pred_label": "__label__POS", "pred_score_pos": 0.9935914278030396}
{"content": "Comparing the CCPA and GDPR\nThe CCPA is similar to the European Union’s General Data Protection Regulation (GDPR), which came into effect in May 2018, in that they both give rights to consumers over their data and define responsibilities. However, the GDPR imposes additional obligations, such as the requirement to ensure that personal data is protected as it crosses borders, and requiring businesses to follow certain rules regarding notice to individuals and regulators when a data breach occurs. You can find more information of what Shopify did to prepare for the GDPR in Shopify’s GDPR whitepaper.\nMuch of the work to prepare for the GDPR applies to the CCPA, but complying with the GDPR doesn't mean that you comply with the CCPA. The GDPR applies to European residents, but the CCPA applies to California residents. The GDPR applies to personal data of data subjects, but the CCPA applies to personal information of consumers and households. The GDPR places requirements on transferring data across borders, but the CCPA places restrictions on the sale of data. Additionally, the GDPR and CCPA have different breach notification requirements and penalties for non-compliance.\nFor more information, download Shopify's CCPA whitepaper (in English).", "pred_label": "__label__POS", "pred_score_pos": 0.8666129112243652}
{"content": "Management International University (MIU) is an online university offering accessible and high-quality diplomas anywhere in the world. Educational attainment is still one of the most precarious issues across\nthe globe. Amidst market volatility, weak institutions, intra conflict zones and ecological challenges, potential students with the capability and aspiration to contribute to the development of their?communities are not reached. Online distance learning still faces obstacles such as technological access, but with development in this area and the ability to access course content on mobile phones, online education alleviates many obstacles. We want to do what we can, using this technology, to ensure that those who want to learn, can.", "pred_label": "__label__POS", "pred_score_pos": 0.5546889305114746}
{"content": "Abstract\nBackground: The use of a simple screening questionnaire to detect persistent airflow obstruction (AO) in COPD may facilitate the early, accurate diagnosis of COPD in general practice settings. Objective: This study developed an original persistent AO questionnaire for screening individuals with COPD in a general Japanese population. Methods: A working group was established to generate initial draft questionnaire items about COPD. Eligible subjects aged 40 and older living in Japan were solicited to participate in a health checkup from 2014 to 2015. In study I, 2,338 subjects who fully completed the initial draft questionnaire and who had valid spirometry measurements were statistically analyzed to determine the final questionnaire items as a COPD screening questionnaire (COPD-Q). Persistent AO was defined as a post-bronchodilator FEV\n1/FVC <0.70. In study II, the working group analyzed the weighted scores for individual items and established a cutoff point for the COPD-Q based on the data of 2,066 subjects in the Hisayama study. Receiver operating characteristic (ROC) curves were used to examine the ability of the COPD-Q to discriminate between subjects with and without AO. Results: The five-item COPD-Q was established based on 19 initial draft items in study I and the weighted scores of individual items. The overall area under the ROC curve for the COPD-Q was 0.796 (95% confidence interval, 0.707–0.788). A cutoff of 4 points resulted in a sensitivity of 71.0% and a specificity of 70.1%. The positive predictive value was 10.8%, and the negative predictive value was 97.9%. The crude odds ratio of the COPD-Q for AO was 5.8. Conclusion: The five-item COPD-Q is a useful questionnaire for diagnosing persistent AO in a general Japanese population and is expected to be an effective first-stage screening tool for detecting COPD. All Science Journal Classification (ASJC) codes Pulmonary and Respiratory Medicine Health Policy Public Health, Environmental and Occupational Health", "pred_label": "__label__POS", "pred_score_pos": 0.5083577036857605}
{"content": "Roxgold continues operations in Burkina Faso Roxgold reports its preliminary production results for the first quarter of 2020 from the its Yaramoko Mine Complex located in Burkina Faso.\n“Yaramoko continues to operate well with a strong quarter to start the year with tonnage and grades ahead of expectations,” says Roxgold President and CEO John Dorward.\n“During these challenging times, we continue to prioritize the health and safety of our workforce and local communities.\n“Mining and production activities have continued uninterrupted, which is a testament to the dedication and fortitude of our team at site.\n“As a company, we remain confident that we can effectively navigate and respond to this rapidly evolving pandemic.\n“The Yaramoko operation has bolstered its safeguards and risk mitigation efforts to limit the impacts of the virus, while the company has strengthened its liquidity position in order to minimize the exposure to operating and financial risks in the market.\n“Looking ahead, we are eagerly anticipating the release of the Séguéla Gold Project PEA shortly and look forward to highlighting the details of what we believe will be Roxgold’s second cornerstone asset.”\nOperating summary\nThe Yaramoko Mine Complex produced 32,380 ounces, based on processing 125,879 tonnes at an average grade of 8.7 grams per tonne and average mill recoveries of 97.9%.\nMining activities continued to see strong ore production with a total of 134,472 tonnes of ore mined and 1,453 metres of development. Decline development in the 55 Zone has now reached the 4754 level, which is approximately 560 metres below surface, with increased ore drive development.\nOre development at Bagassi South has commenced on the 5095 level, which is approximately 220 metres below surface, while the decline continues to advance as planned. Good progress on ore development has seen the Bagassi South mine largely developed, providing additional stoping access for the remainder of the year.\nThe processing plant availability was 96.4% in the quarter and reported an average throughput rate of 1,383 tonnes per day exceeding nameplate capacity by approximately 26%.\nAverage throughput was lower in the quarter due to a planned 39-hour mill shut down for a complete mill relining. Gold ounces sold of 30,126 ounces were lower than production due to the timing of gold shipments at the end of the quarter.\nUpdate on COVID-19 response\nManagement of the current global COVID-19 crisis is ongoing. Operations at Yaramoko currently remain unaffected with heightened preventative measures and response plans in place to mitigate and minimize any potential impacts from the virus.\nThe Company is continually assessing the health and safety risks to the Company’s personnel and contractors at its operations and offices.\nOn the 22 March 2020, the Company announced that two contractors at the Yaramoko mine in Burkina Faso tested positive for COVID-19. Both cases experienced only mild symptoms and have now recovered.\nAdditionally, a majority of the previously isolated workers who were identified via contact-tracing have returned to the workforce after completing their prescribed isolation periods and testing.\nThe Company has continued to enhance its testing and on-site medical support as well as reducing all non-essential mine site personnel. It has also increased the supply chain thresholds for consumables which will enable the mine to operate for extended periods.\nWhile Yaramoko continues to operate in accordance with the annual operating plan, several contingency plans have been developed in the event that underground mining rates were affected by a prolonged Covid-19 related interruption.\nThese options include the processing of surface stockpiles, of which there is approximately four months of low-grade material (~3g/t Au) available.\nLiquidity position\nRoxgold finished the quarter with approximately $50 million of cash and gold doré on hand. The Company strengthened its liquidity position in the quarter following the drawdown of the remaining $15 million of its revolving credit facility to maximise cash reserves and reduce liquidity risk given the volatile and uncertain financial market conditions.\nIn addition, the Company continues to make regularly scheduled gold shipments from Yaramoko. Earlier this week, the quarter ending gold doré balance of 3,662 ounces, together with an additional 2,974 ounces poured since the start of April, was shipped from site further underpinning the Company’s liquidity position.\n2020 Guidance\nBased upon Q1 production results, Roxgold is slightly ahead of expectations and remains on track to deliver between 120,000 and 130,000 ounces of production from\nYaramoko absent any significant deterioration in operating conditions.", "pred_label": "__label__POS", "pred_score_pos": 0.7674323320388794}
{"content": "The model for EI in project management includes 5 factors: self-awareness, self-management, self-motivation, interpersonal management, and leadership.\nSELF-AWARENESS\nThis is “the ability to sense, identify and understand emotions”. A project manager with low self-awareness is like a person being handicapped. Without awareness, we cannot make changes. It is crucial for a project manager to know his feelings and then make decisions, or take action. Otherwise, we may make poor decisions resulting in unintended outcomes. Those with a high level of self-awareness are confident, responsive to feedback and maintain their own perspectives during the project.\nSELF-MANAGEMENT\nAnother step further for a project manager after knowing and understanding his feelings is to know how to manage their responses to their emotions in order to make a rational decision rather than reacting. Self-Management is “using your understanding of your feelings to reason well”. Those with high level of self-management understand their feelings and choose to manage their responses to the feelings.\nSOCIAL AWARENESS\nSimilar to self-awareness, which is the ability to understand your emotions, social awareness, the third component in the five building blocks of our project management framework for emotional intelligence, is “the ability to understand the emotions of others”.\nThis involves empathy, which is “putting yourself in another person’s place to understand how they feel and why they feel that way”. The key to empathy is to “suspend judgment” and to listen and understand their feelings and emotional condition.\nRELATIONSHIP MANAGEMENT\nStakeholder relationships play a critical role in any project. A project manager must manage the project team, and more difficult, the stakeholders. Whether you have a good relationship with them is up to you. We must claim the higher ground in building relationships.\nTEAM LEADERSHIP\nThis is the highest component in the model of EI for project management. Communicating is crucial for a project manager to understand and manage the emotional tone of the team while managing conflict is a precious aspect of team development. And delivering inspirational leadership is necessary. It involves motivating, engaging and inspiring your team to develop for themselves and for the team.\nTo gain thorough understanding of 6 EI components for project managers, enroll in this course on Emotional Intelligence for Project Managers. Register now and earn 8.25 PDUs of Leadership for all kinds of PMI certificates after taking this course and receive a 50% discount. You can look for the course information on PMI CCRS: https://ccrs.pmi.org/search/course/451898\nReference:\n- Casper, C. M. (2002). Using emotional intelligence to improve project performance. Paper presented at Project Management Institute Annual Seminars & Symposium, San Antonio, TX. Newtown Square, PA: Project Management Institute.\n- Rechtfertig, G. (2010). Emotional intelligence and key principles to increase your capacity to succeed. Paper presented at PMI® Global Congress 2010—North America, Washington, DC. Newtown Square, PA: Project Management Institute.\nIMT-PM - Global PMI R.E.P. #4760 offers various courses for PMP® Exam Preparation and PMP®/PgMP®/PMI-ACP®/PMI-RMP® Renewal.\nOur best sellers are: 60 PDU Bundle: https://online.imt-pm.com/course/60-pdus-bundle-70 50 PDU Bundle: https://online.imt-pm.com/course/50-pdus-bundle-75 39 PDU Bundle: https://online.imt-pm.com/course/39-pdus-bundle-76 PMP Exam Preparation 35 PDU: https://online.imt-pm.com/course/pmp®-exam-preparation-38 PMP Exam Simulator: https://online.imt-pm.com/course/pmp®-exam-simulator-full-40", "pred_label": "__label__POS", "pred_score_pos": 0.5066449046134949}
{"content": "Abstract\nCranial neural crest (CNC) cells are patterned and coalesce to facial prominences that undergo convergence and extension to generate the craniofacial form. We applied a chemical genetics approach to identify pathways that regulate craniofacial development during embryogenesis. Treatment with the nitric oxide synthase inhibitor 1-(2-[trifluoromethyl] phenyl) imidazole (TRIM) abrogated first pharyngeal arch structures and induced ectopic ceratobranchial formation. TRIM promoted a progenitor CNC fate and inhibited chondrogenic differentiation, which were mediated through impaired nitric oxide (NO) production without appreciable effect on global protein S-nitrosylation. Instead, TRIM perturbed hox gene patterning and caused histone hypoacetylation. Rescue of TRIM phenotype was achieved with overexpression of histone acetyltransferase kat6a, inhibition of histone deacetylase, and complementary NO. These studies demonstrate that NO signaling and histone acetylation are coordinated mechanisms that regulate CNC patterning, differentiation, and convergence during craniofacial morphogenesis.", "pred_label": "__label__POS", "pred_score_pos": 0.7665328979492188}
{"content": "Nearly four decades ago, a highway expansion project resulted in the excavation of 35 unmarked graves at Catoctin Furnace, an industrial ironworking village in western Maryland. Initial analysis identified the remains as Africans or African Americans associated with the late 18th- and early 19th-century operation of the ironworks. Renewed efforts to learn more about these poorly documented individuals and connect the site's untold past to present generations through heritage tourism, prompted reanalysis of the skeletons. Updated assessments of demography and pathology, along with new analyses including heavy metals and carbon and nitrogen stable isotopes, elucidate the life histories of these early laborers and their involvement in furnace operations. Some data derived from recent testing differentiate the Catoctin Furnace individuals from their plantation-based contemporaries in the mid-Atlantic, suggesting regional differences in diet and possible occupational exposure to toxins.", "pred_label": "__label__POS", "pred_score_pos": 0.7727581858634949}
{"content": "College and university students need a secure environment that fosters positive growth, with guidance from professionals who can prevent issues in the students' lives from inhibiting their development. Students are supported by staff members who provide comprehensive counseling and referral services that help them achieve their educational goals, strengthen their problem-solving skills, develop healthy relationships, and reach their full potential for continued growth after graduation.\nThe 36-credit-hour Master of Arts with a major in Counseling offers a specialization in Student Development Counseling and Administration. Upon degree completion, graduates will be prepared to utilize a student-centered approach in applying counseling skills and techniques in the field of student development. Participants will take advantage of Indiana Wesleyan University's innovative approach to college student development which includes the Center for Life Calling and Leadership, successful first-year program initiatives, and dynamic residence life, activity, and mentoring programs. Graduates will be qualified to serve in the higher education realm in areas such as residence life, student activities, career counseling, multicultural affairs, admissions, academic advising, financial aid, and mentoring.\nCourses can be completed to earn a Master's in Student Development online or at our Marion or Indianapolis (West) campuses. Those pursing a certificate in Student Development and Counseling Administration may also complete their coursework online. Internships can be completed at the site of the student's choice.", "pred_label": "__label__POS", "pred_score_pos": 0.7201301455497742}
{"content": "Robobank Provides Bearish View of Fertilizer, with Exception of Urea\nBy Amanda Brodhagen, Farms.com\nRabobank published its most recent report on the global fertilizer industry, which forecasts oversupply through Q1, 2013, with the exception of urea. The bank predicts that global fertilizer will remain range-bound, with market fundamentals staying balanced through Q1.\nThe global trading of fertilizer was slow through Q4 2012, with price changes being mixed in fertilizer. However, demand on Q4 is typically lower due to factors such as seasonality. “Looking ahead, as agricultural markets are faced with the challenge of rebuilding global stocks next season, and given the precariously balanced fundamentals, global agri commodity prices are expected to remain at elevated levels in 2013,” says Rabobank analyst Dirk Jan Kennes. Urea global markets were high - but flat through Q4, 2012. On the demand side of the equation, Granular urea prices experienced a premium over prilled urea. Rabobank predicts that Q1 for urea will be largely driven by the Northern Hemisphere. Important markets to watch will be India and China.", "pred_label": "__label__POS", "pred_score_pos": 0.9932341575622559}
{"content": "If you are like most Iowa residents burdened by unmanageable debt, you have probably taken your struggle as an opportunity to plan your future. Whichever debt management strategy you choose might have a significant impact on your credit going forward. For example, bankruptcy carries a relatively lasting repercussion: Credit reporting companies may report bankruptcy data for ten years after your bankruptcy becomes official.\nThis ten-year duration begs the question of why you would want to declare bankruptcy in the first place. The answer to this common question might be divided into two parts.\nFirst, bankruptcy remains a viable option because it does not preclude you from receiving loans. As explained by the Federal Trade Commission, a credit report score is simply a representation of your outlying debts and your available credit. Individual entities, such as banks or prospective employers are free to use information from your report in any way they choose. Common examples include:\nDetermining your credit card terms during the application process Approving you for a loan Deciding whether to accept you for a job opportunity\nDamaged credit might factor into a decision, but it is typically not the only factor. Furthermore, bankruptcy is merely one aspect of these complicated reports.\nThe second part of the answer is that bankruptcy might prevent you from damaging your credit further. The FTC notes that certain types of loans might adversely affect your credit score, such as those issued by financing companies. It might require some serious calculations, but it could be worth it for you to establish and then compare long-term timetables for your debt management strategies. This process could be instrumental in determining which route helps you heal your credit more expeditiously. Please do not consider this article as legal advice— it is simply an introduction to the subject.", "pred_label": "__label__POS", "pred_score_pos": 0.807608962059021}
{"content": "CLOUD COMPUTING.\nCloud computing is the on-demand availability of computer system resources, especially data storage and computing power, without direct active management by the user. The term is generally used to describe data centers available to many users over the Internet. Large clouds, predominant today, often have functions distributed over multiple locations from central servers. If the connection to the user is relatively close, it may be designated an edge server.\nBACKUP & RECOVERY.\nBackup and recovery describes the process of creating and storing copies of data that can be used to protect organizations against data loss. This is sometimes referred to as operational recovery. Recovery from a backup typically involves restoring the data to the original location, or to an alternate location where it can be used in place of the lost or damaged data.\nA proper backup copy is stored in a separate system or medium, such as tape, from the primary data to protect against the possibility of data loss due to primary hardware or software failure.\nIT SECURITY.\nInformation security, sometimes shortened to infosec, is the practice of protecting information by mitigating information risks. It is part of information risk management. It typically involves preventing or at least reducing the probability of unauthorized/inappropriate access, use, disclosure, disruption, deletion/destruction, corruption, modification, inspection, recording or devaluation, although it may also involve reducing the adverse impacts of incidents. This is largely achieved through a structured risk management process that involves:\n– Identifying information and related assets, plus potential threats, vulnerabilities and impacts;\n– Evaluating the risks; – D-eciding how to address or treat the risks i.e. to avoid, mitigate, share or accept them; – Where risk mitigation is required, selecting or designing appropriate security controls and implementing them; – Monitoring the activities, making adjustments as necessary to address any issues, changes and improvement opportunities. ON-GOING SUPPORT.\nDepending on needs, support can be ongoing and indefinite, unless the employee is exited as independent. DES are contracted by the Government to provide support in employment. However, the ultimate goal is to facilitate the relationship between the employer and employee.", "pred_label": "__label__POS", "pred_score_pos": 0.9394519329071045}
{"content": "Advise the patient to avoid high-risk activities. Instructions include the following:\nAvoid strenuous athletic activities, particularly those involving Valsalva maneuvers such as weight lifting.\nAvoid playing woodwind instruments.\nAvoid barotrauma from activities such as flying, parachuting, or scuba diving.\nMaintain good asthma control. Ensure that influenza and pertussis vaccinations are current.\nAvoid smoking and inhalation of illicit drugs.", "pred_label": "__label__POS", "pred_score_pos": 1.0000100135803223}
{"content": "All brands are born the same way: from a business idea. However, thriving brands are those which succeed in find what makes their idea different from the others and potentiate it.\nHighlight the differential value presents the brand in an authentic way, allows people to engage easily with the product or service and offers a significant advantage over the competition. To reveal the differential value, each brand is shaped and visualized through analytical research, strategic insight and clever design.\nBusiness attributes\nVisual and verbal assets Strengths and weaknesses Industry territories Branding trends Target behaviours and needs Benchmarking against competitors Inspiring Brands Positioning possibilities Differentiation opportunities Short and long term goals Real assignments for the project\nUsed to create effective visual solutions that seizes differentiation opportunities.", "pred_label": "__label__POS", "pred_score_pos": 0.9221570491790771}
{"content": "Abstract\nMacromonomers bearing a functional group exclusively at one end are often synthesized by terminating a living polymerization with a suitable agent, at the cost of one initiator molecule per chain. An attractive alternative is to use chain transfer to install the functional endgroup. Herein, polycyclopentene (PCP) bearing a single styryl endgroup is synthesized by ring-opening metathesis polymerization with a well-defined Mo-based (Schrock) initiator, by employing divinylbenzene as a chain-transfer agent. High regioselectivity of the chain-transfer step, with minimal secondary metathesis of double bonds in the PCP backbone, is confirmed by mass spectral endgroup analysis. A styryl-functional PCP macromonomer copolymerizes effectively with styrene in a free-radical process (styrene reactivity ratio r\nS ≈ 1.7), producing a comb copolymer with a polystyrene backbone and PCP \"teeth\". All Science Journal Classification (ASJC) codes Organic Chemistry Polymers and Plastics Inorganic Chemistry Materials Chemistry", "pred_label": "__label__POS", "pred_score_pos": 0.9230058789253235}
{"content": "Interruptions are inevitable in the clinical environment, and they have been linked to an increased risk of diagnostic errors by radiologists and medication administration errors by nurses. However, the effects of interruptions are not predictable and many interruptions are essential for proper patient care. Recognizing this, commentators have called for research to analyze the causes and effects of interruptions, rather than attempting to categorically prevent interruptions. This study, conducted in an academic emergency department, contributes to our understanding of how interruptions influence patient care by examining the effect of interruptions on several specific nursing tasks. Interventions that were interrupted took longer than uninterrupted tasks, and interruptions were a significant contributor to overall nursing workload. Patients and families were the most frequent source of interruptions, demonstrating that simply implementing interventions to prevent interruptions could cause unintended consequences. The state of patient safety in the emergency department, including the role of interruptions, is discussed in a past AHRQ WebM&M perspective.", "pred_label": "__label__POS", "pred_score_pos": 0.9886626601219177}
{"content": "There’s already been some pundits claiming autocratic countries have been handling the pandemic better than democratic countries. This piece on the website for the Carnegie Endowment for International Peace argues differently. It’s worth reading, but a key part of the piece is this:\nDespite attempts by politicians to use the crisis to tout their favored political model, the record so far does not show a strong correlation between efficacy and regime type. While some autocracies have performed well, like Singapore, others have done very poorly, like Iran. Similarly, some democracies have stumbled, like Italy and the United States, while others have performed admirably, like South Korea and Taiwan. The disease has not yet ravaged developing countries, making it impossible to include poorer autocracies and democracies in the comparison.\nKeep this in mind, especially afterwards, when writers and authorities argue that we need more controls on people to fight future pandemics.", "pred_label": "__label__POS", "pred_score_pos": 0.9993497729301453}
{"content": "By Daniel Dunaief\nWe pack our cars, suitcases and purses. We bring cameras, camcorders, extra batteries, chargers and cards filled with positive messages and gifts.\nAt this time of year, we bear witness to the conclusion of one educational course — primary, middle or high school, college or even graduate school — as we and the graduate prepare for the next step.\nIn between bites from the buffet, we pause for proud pictures with the graduate and we share our admiration for what he or she has accomplished even as we anticipate the next adventure.\nMost of these ceremonies involve walking, sitting, standing and cheering, eating and driving. The action takes a backseat to the words and sentiment that mark the occasion. The graduation speakers offer personal anecdotes and words of wisdom, even as they recognize that short speeches, particularly for those eager to fill an empty stomach or discharge a full bladder, are a welcome part of the day.\nWhile we’re milling around, we have ample opportunities to impart our own wisdom, to share encouraging words and to provide the kind of tailwind that accelerates the next phase of life.\nSo, what do we say? Did we pack our belongings, but neglect to choose from the wealth of words that can fill a sail with air, that can help us feel capable of defying gravity, that can enable us to see through this moment to a magnificent future?\nHow often do we watch an interview with someone who has accomplished the unimaginable, who doesn’t know what to say or who is it at a loss for words when someone shoves a microphone in that person’s direction?\nWe have time to consider the right words, to be supportive, and to make our trip to another state or another school meaningful, even if the graduate is too close to the focal point of his or her life to know how to react to the torrent of feelings and thoughts.\nWe can rely on a Hallmark card, a Thesaurus or a set of clichés to share our thoughts, or we can take a moment to find the right words, in between all our packing, our search for the right gift and our purchasing plane tickets.\nSomeday, a daughter graduate may be sitting on a plane heading for a meeting in Salt Lake City and may wonder how she got there and whether she can succeed in the next phase. Maybe she’ll recall the moment you took her aside, placed your hand on her shoulder, smiled in her eyes and suggested she paved her own path with perspiration — if she appreciates alliteration.\nShe may recall how you enveloped her hand in yours when you reminded her that everything, even a moment of weakness, provides opportunities for the next success. Perfection, she’ll recall as she remembers how you accidentally spit on her cheek when you started to speak, isn’t about the perfect achievement but about the perfect effort.\nShe will recall the moment you told her how much she inspired you with her awareness of the needs of others and with her grace under pressure.\nIf your graduate is anything like the ones in my family, for whom skepticism and cynicism hover nearby, he or she may roll their eyes and search for a phone to text a friend to ask if the recipient of the message can believe what you just said.\nSomeday, the graduate or that friend may borrow a word, phrase or idea from the ones you shared, providing fuel to a tank that seemed empty and converting the next impossible task into a reality.", "pred_label": "__label__POS", "pred_score_pos": 0.7394892573356628}
{"content": "In a previous blog post, we mentioned the possibility of amendments to Florida’s direct file system, which would potentially narrow the range of juvenile offenses eligible for trial as an adult offender. This proposed amendment, along with a proposed bill aimed at increasing eligibility for records expungement, sit atop the Legislature’s docket for the upcoming sessions – prompting many to reconsider the plight of young offenders charged with crimes, which is a potentially life-altering experience.\nCiting the sheer immaturity of many juvenile offenders, advocates for this demographic reiterate the realistic effects of teenage indiscretions on offenders’ ability to obtain housing, employment and education later. Accordingly, lawmakers are making strides toward equalizing the playing field for many of Florida’s juvenile offenders while ensuring that punitive measures are, in fact, consistent with the crime committed – and not unintentionally burdensome through adulthood.\nExpungement Reform\nExpungement is a process through which a former offender may apply to have his or her criminal record removed from permanent record. Currently, there are a number of legal hurdles and obstacles awaiting anyone wishing to expunge a juvenile criminal record, and a high number of applications are denied each year. Moreover, anyone seeking an expungement – which is often necessary to seek enrollment in a college or university – must wait until they are at least 24 years old, making the process additionally (unnecessarily) burdensome for those wishing to move past their arrest and conviction.\nUnder the proposed reforms, the age at which a former offender may seek expunction would be reduced from 24 to 21. The process would still only be reserved for non-habitual, non-violent offenders, but would allow young adults the opportunity to advance in life toward academic and career goals much faster than would otherwise be possible.\nProponents of the changes also point out the positive effect of expungement for those children who live in Florida’s foster care system, noting that a significant portion of these children commit juvenile indiscretions as early as 10 or 11 years of age. By 18, these same children are often looking to enroll in college or the military, and could be unduly hindered by mistakes made years prior.\nExpungements are currently obtained through the Florida Department of Law Enforcement (FDLE). Some former juvenile offenders are eligible for expungement upon completion of a diversion program. Others must obtain a Certificate of Eligibility from FDLE stating that the applicant is statutorily eligible for expungement. In either event, the applicant must gain ultimate approval for expungement by petitioning the court to enter an order as such – which may be denied at the discretion of the judge.\nContact a Sarasota Juvenile Attorney for Help Today!\nIf you are considering an expungement or would like to discuss your rights following a recent criminal charge, please contact the Fowler Law Group today: 941-404-8909.\nHear What Our Clients Have To Say HAVE YOU RECENTLY FACED LEGAL ISSUES? WE CAN HELP!\nFowler Law Group proudly represents the citizens of Sarasota and Manatee Counties as well as the surrounding Tampa Bay area. Our experienced team will help guide you through the judicial process and answer all of your questions with honesty and integrity. We understand the important nature of your call, and we will strive to return all calls within 24 hours. Contact us today by completing our online form or calling us at 941-404-8909.", "pred_label": "__label__POS", "pred_score_pos": 0.533241868019104}
{"content": "The value of global textile and apparel exports totalled USD $736 billion in 2015, according to the latest World Trade Statistical Review 2016 by the World Trade Organization (WTO). Specifically,\nA Dutch initiative, the Circle Textile Program aims to transform the textile industry into a ‘zero-waste’ industry by addressing all the loopholes around post-consumer textiles. This program has been conceived", "pred_label": "__label__POS", "pred_score_pos": 0.9998599886894226}
{"content": "An update for members on the Academy’s work on licensure, particularly in Florida, since the most recent communication on July 28.\nAn update for members on the Academy’s work on licensure, particularly in Florida, since the most recent communication on July 28.\n07/28/2020 - On June 30, Florida Gov. Ron DeSantis signed a bill updating the state's Dietetics and Nutrition Practice Act, aligning it more closely with the Academy of Nutrition and Dietetics' Model Practice Act.\n07/06/2020 - The bill updates Florida’s dietetics licensure law to align more closely to the Academy’s Model Practice Act.\n03/12/2020 - The Florida Senate and House have passed amended legislation that maintains professional competencies of health care practitioners with expertise in nutrition care services.\n01/13/2020 - New Jersey Governor Phil Murphy signed into law the strongest, most comprehensive nutrition and dietetics licensure bill in a generation.\n11/19/2019 - The New Jersey Senate Committee on Commerce unanimously passed S2625, which will be voted on by the full state senate later this year.\n09/11/2019 - Earlier this week, the New Jersey Academy of Nutrition and Dietetics announced its launch of a virtual water drive to benefit Newark residents.\n07/19/2019 - The lawsuit challenging the Florida Dietetics and Nutrition Practice Act in the United States District Court in the Northern District of Florida Pensacola Division would have had a dire impact on our profession.\n03/27/2019 - The Academy's online licensure map now provides registered dietitian nutritionists with additional information to facilitate their practice across state lines.\n02/13/2019 - Proposed legislation in Missouri, Montana and North Dakota would eliminate states' ability to to require that providers of nutrition care services have the necessary education and training to provide them.\n02/04/2019 - The Academy has joined other organizations in a national campaign to address state-level policies for obesity care including access to nutrition counseling, medications and surgical treatment.\n11/19/2018 - The Council of the District of Columbia amended its licensure law to enable the Board of Dietetics and Nutrition to add new members and clarify the necessary qualifications.\n07/30/2018 - A new regulation in the state of Tennessee will enable registered dietitian nutritionists to order therapeutic diets in hospitals.\n06/15/2018 - The Modernize Dietetics/Nutrition Practice Act passed the North Carolina legislature on June 14, providing additional opportunities for RDNs to practice at the height of their scope of practice.\n11/21/2017 - The Cook County Board of Commissioners passed a resolution honoring the Academy's Centennial.", "pred_label": "__label__POS", "pred_score_pos": 0.7087236642837524}
{"content": "LAS VEGAS — If a newborn girl develops vesicles or pustules over the trunk and extremities, think incontinentia pigmenti, Dr. Moise L. Levy said at meeting sponsored by the American Academy of Pediatrics' California Chapters 1, 2, 3, and 4 and the AAP.\n“With incontinentia pigmenti you'll have a staged eruption, with vesicles or pustules at the time of birth within the first weeks, followed by more warty or verrucous papules,” said Dr. Levy, professor of dermatology and pediatrics at Baylor College of Medicine, Houston.\nBy the first year of life a swirling gray-brown hyperpigmentation develops. “This is due to incontinence of pigment,” he explained. “Melanin has dropped out of the basal layer of epidermis into the upper dermis.” The condition occurs primarily in females and is marked by staged cutaneous eruptions.\n“You should regard it as a potentially neurocutaneous syndrome,” said Dr. Levy, also chief of the dermatology service at Texas Children's Hospital, Houston. “Eosinophilia can be seen during stage 1, which is the vesicular stage.”\nThe gene for incontinentia pigmenti has been mapped to Xq28. Deletions at this site cause mutations in NF-kB essential modulator (NEMO), which governs a variety of inflammatory and immune responses. These mutations can lead to skin lesions, vascular anomalies, and immune dysfunction.\nDr. Levy noted that 80% of incontinentia pigmenti cases are caused by mutations in NEMO. Management of the skin lesions is generally supportive. Careful ophthalmologic and neurologic follow-up is indicated in some cases.\nAt the meeting, Dr. Levy also discussed the clinical signs of another skin defect that can affect newborns: aplasia cutis congenita. This condition is marked by focal congenital skin defects that most often appear on the scalp or face. It also can occur along the temporal area, a version known as focal facial dermal hypoplasia.\nAplasia cutis congenita is “rarely on the trunk or extremities, though this can happen anywhere,” he said. “The etiologies are really varied and may include vascular insufficiency, intrauterine infections, and amniotic membranes. On the scalp, this might be due to defects of closure.”\nIn your work-up, consider these malformation syndromes that may be associated with aplasia cutis congenita: Opitz syndrome, Adams-Oliver syndrome, Trisomy 13–15 syndrome, 4p syndrome, Johanson-Blizzard syndrome, and Xp22 microdeletion.\nSome cases of aplasia cutis congenita will have a so-called hair collar sign, which is a ring of dark hair that often surrounds a scalp lesion. The hair collar sign “suggests cranial dysraphism, especially with overlying vascular malformation.”", "pred_label": "__label__POS", "pred_score_pos": 0.8411636352539062}
{"content": "An Annapolis Psychiatrist Offers a Comprehensive Guide on Manic Behavior\nThe term “mania” can refer to a couple of different things. Some people use it when referring to someone with an obsession or excessive enthusiasm toward something. For example, someone could have a “mania” for superhero films. Other times, “mania” refers to temporary periods of euphoria and delusions. In the second case, these manic episodes are often associated with bipolar disorder.\nBipolar disorder is a serious mental health disorder that includes episodes of extreme euphoria as well as periods of extreme depression. People with bipolar disorder might have trouble maintaining relationships or managing a stable work life. But it is possible to manage these symptoms and lead a normal life. An Annapolis psychiatrist from the Psych Associates of Maryland explores this mental health disorder in our latest blog post.\nWhen people think of bipolar disorder, common symptoms of mania and depression often come to mind. Unfortunately, this disorder is often misunderstood by people. They might believe that having bipolar disorder involves being moody or temperamental. If a friend is having a bad day and is acting ornery, someone might be inclined to say, “Ugh, they’re so bipolar!”\nBut the disorder goes much deeper than that. Both manic and depressive episodes can last for weeks and have devastating effects on one’s life. Let’s explore the complexities and challenges of this disorder together.\nAs we mentioned before, bipolar disorder is characterized by extreme mood shifts. The frequency of these mood swings varies among patients. Some people rarely experience mood swings while others deal with them several times a year.\nSymptoms of a manic episode include:\nUnfortunately, this manic period doesn’t last forever. At some point, you will come down and experience a depressive episode. While the number of episodes you experience may vary, you’ll experience a depressive episode at some point if you have bipolar disorder. Symptoms of a depressive episode include:\nSome people wonder if it is possible to prevent manic episodes altogether. While there’s no magical medicine or tried and true practice that comes with a 100% guarantee for prevention, there are numerous steps you can take to identify the early warning signs of a manic episode and try to prevent it. This includes:\nDealing with the effects of a manic episode can be difficult. You might have hurt your loved ones, taken unwise financial risks, and compromised your career. Having a strong support system will be crucial during the aftermath of your episode. If you have a mental health therapist, they will also play a large role in your recovery.\nWhen it comes to managing your bipolar disorder, you can’t do it alone. That’s why it’s crucial for you to seek medical attention if you believe you might have the disorder. Your primary care physician can refer you to a mental health specialist who can craft a treatment plan for you. They might also prescribe medication for you. As your treatment progresses, your psychiatric care provider might make some changes or adjustments to it. Therefore, checking in with them on a regular basis will be important.\nIf you or someone you know is struggling with symptoms of bipolar disorder, know that there is help out there. Our team of Annapolis psychiatrists at the Psych Associates of Maryland is ready to help you or your loved one. Our services include psychotherapy, medication management, telehealth services, TMS, ABA, and psychological testing. Start taking back control of your mental health and contact the team today for more information.\nFill in your name and email and we will send you updates when new content is available!", "pred_label": "__label__POS", "pred_score_pos": 0.5109172463417053}
{"content": "Abstract\nHow does foreign support for separatists influence conflict escalation with the central government? What types of miscalculations over foreign support encourage separatists to take risky gambles and lead to surprising losses? Existing research indicates that armed non-state actors may initiate or escalate conflict with the central government when existing or anticipated gains in foreign support favorably alters their likelihood for success. This article sheds light on an additional but equally important catalyst for conflict escalation: rebel, or separatist, beliefs about net losses of foreign support in their gamble for more autonomy. Even if groups have perfect information on potential gains in foreign support, miscalculations over potential losses can also lead to risky gambles. To illustrate the distinction between separatist miscalculations over gains and losses in foreign support, this paper compares two episodes of Iraqi Kurdish escalation: the 1991 uprising against Saddam Hussein in the aftermath of the Gulf War, and the 2017 independence referendum after three years of war against the Islamic State. While the former case is a classic example of escalation based on miscalculating gains in foreign support, the latter case represents a miscalculation over potential losses of foreign support in response to the vote.\nASJC Scopus subject areas Cultural Studies History Political Science and International Relations", "pred_label": "__label__POS", "pred_score_pos": 0.9388181567192078}
{"content": "Abstract\nPaired-pulse transcranial magnetic stimulation (TMS) of the human motor cortex results in consecutive facilitatory motor-evoked potential (MEP) peaks in surface electromyography in intact humans. Here, we tested the effect of an incomplete cervical spinal cord injury (SCI) on early (first) and late (second and third) MEP peaks in a resting intrinsic finger muscle. We found that all peaks had decreased amplitude in SCI subjects compared with controls. The second and third peaks were delayed with the third peak also showing an increased duration. The delay of the third peak was smaller than that seen in controls at lower stimulation intensity, suggesting lesser influence of decreased corticospinal inputs. A mathematical model showed that after SCI the third peak aberrantly contributed to spinal motoneurone recruitment, regardless on the motor unit threshold tested. Temporal and spatial aspects of the late peaks correlated with MEP size and hand motor output. Thus, early and late TMS-induced MEP peaks undergo distinct modulation after SCI, with the third peak likely reflecting a decreased ability to summate descending volleys at the spinal level. We argue that the later corticospinal inputs on the spinal cord might be crucial for recruitment of motoneurones after human SCI.\nKeywords corticospinal volleys primary motor cortex spinal cord injury transcranial magnetic stimulation voluntary movement ASJC Scopus subject areas Cognitive Neuroscience Cellular and Molecular Neuroscience", "pred_label": "__label__POS", "pred_score_pos": 0.7515008449554443}
{"content": "The lowdown on resuscitation in Nevada\nIf you have had a loved one with a terminal condition or have watched some medical dramas on TV, you may have heard the term “DNR,” an acronym for Do Not Resuscitate. A DNR directs emergency medical personnel not to use resuscitation efforts (e.g., CPR, defibrillation, intubation, etc.) to revive a terminally ill individual, generally where it would only serve to prolong the person’s suffering. Without a DNR, emergency personnel have a legal duty to try to resuscitate you. Only a valid DNR relieves them of that duty.\nIn Nevada, “qualified patients” may obtain a DNR if a doctor certifies that the person suffers from a terminal condition and the person submits an application to the board of health. If approved, the person is issued a DNR identification card. However, the card is only helpful if emergency personnel are aware of it.\nSome use DNR bracelets, necklaces and even tattoos to advise emergency responders that they have a DNR card, which they might carry in their purse or wallet. Medical personnel are required to honor a valid DNR.\nSome people mistakenly believe DNRs, health care powers of attorney, and living wills (advance physician directives) are one and the same. However, while they are all related to your healthcare desires, each generally serves a different function. For example, health care powers of attorney and living wills address the withdrawal of life sustaining treatments but normally do not directly address emergency resuscitation.\nThose wanting to avoid resuscitation efforts should discuss their wishes with family members, care providers, and close friends who can help inform emergency personnel or provide the DNR card if the need arises. Finally, obtaining a DNR does not invalidate life insurance and a DNR can be revoked at any time.\nBo Bingham lives in Mesquite and is an attorney with Bingham Snow & Caldwell. He is licensed to practice in Nevada, Arizona and Utah. He can be reached at 702-346-7300, bo@binghamsnow.com , or at 840 Pinnacle Ct., Ste. 202 in Mesquite.", "pred_label": "__label__POS", "pred_score_pos": 0.6953268051147461}
{"content": "Powering down key components and sending out a highly qualified engineer to connect/disconnect safety equipment is a lengthy, complex and expensive process. It also presents a risk to your workers and assets as engineers are entering hazardous environments to open the junction box, exposing other connections to contaminants, such as sea water and construction dust.\nOur Ex connectors’ rear-loading assembly system allows complete cable termination in just a few minutes and requires no proprietary tools or equipment, resulting in massively increased uptime for rigs, key oil and gas machinery and temporary equipment.\nIn addition to gas detectors, we have developed a unique particulate monitoring system that uses lab-grade precision laser technology to accurately and continuously identify multiple hazardous particulates of different sizes. This includes construction dust, cement dust, respirable crystalline silica dust (RSC) – checked in real-time by a dust monitor that delivers incredible accuracy even in heavy dust loads, and which requires no pumps or filters to operate.\nThe Internet of Things (IoT) and Artificial Intelligence are set to transform safety standards in hazardous environments. How can new, innovative monitoring equipment support the new, data driven, real-time management of employee well-being? Download our eBook to find out!", "pred_label": "__label__POS", "pred_score_pos": 0.7696722745895386}
{"content": "Phoenix-Mesa, AZ – Prolonged and intense combat have increased the severity of harm done to U.S. soldiers, and the November 2010 issue of Arizona Attorney magazine features stories that explore how lawyers and judges are assisting those who have served in harm’s way.\nArizona Attorney’s special section “Homeland Justice for Veterans” includes stories that explore efforts to launch a specialized court dedicated to veterans and their needs. The first article was written by Craig Logsdon and Michelle Keogh, attorneys in the criminal defense group at Snell & Wilmer LLP.\nLogsdon and Keogh chronicle a veteran’s struggle with post-traumatic stress disorder (PTSD) and its effects on his civilian life in the article “Uncommon Criminals: Why Veterans Need Their Own Court.” It leads the reader on a journey from a veteran’s time on the battlefield to the legal challenges he faces due to criminal activity attributed to his war-related PTSD. It also dissects the current justice system, reveals its disconnect with veterans, and argues why a veterans court would work.\nArizona Attorney magazine is available for free to anyone online by visiting the magazine homepage at http://www.myazbar.org/azattorney/ and clicking on the image of the magazine cover.\nThe second article, written by Nicole Kasem and lawyer Jon Paladini, reports on the State Bar of Arizona’s commitment to addressing the legal needs of veterans through the creation of its Military Legal Assistance Committee. It is led by attorney Gregg Maxon, a retired Army General.\nIn the final article, Steve Gonzales, Associate Professor of Law and the Director of Experiential Learning at the Phoenix School of Law, announces two new programs housed at the law school aimed at helping veterans-the Veterans Legal Assistance Clinic and the Veterans Tax Clinic.\n“Veterans have always deserved our country’s best efforts when they return stateside,” said Tim Eigo, Arizona Attorney Editor. “Conflicts in recent years have heightened the number and severity of their injuries, and the legal community is doing what it can to assist those who have served.”\nThe striking art for the cover and feature stories was created by nationally renowned artist Val Bochkov. It was commissioned by Arizona Attorney magazine to illustrate the November issue’s veteran-related stories.\nArizona Attorney magazine is published 11 times per year by the State Bar of Arizona. It provides articles on substantive legal issues, professional trends and feature profiles.\nThe State Bar of Arizona is a non-profit organization that operates under the supervision of the Arizona Supreme Court. The Bar includes approximately 16,000 active attorneys and provides education and development programs for the legal profession and the public. Since 1933 the Bar and its members have been committed to serving the public by making sure the voices of all people in Arizona are heard in our justice system.\nSource:\nhttp://www.1888pressrelease.com/veterans-court/military-legal-assistance/campaign-to-create-veterans-court-the-focus-of-november-2010-pr-255865.html\nhttp://www.azbar.org/", "pred_label": "__label__POS", "pred_score_pos": 0.8697124719619751}
{"content": "Overview\nFood security analysis for rural populations dependent on Belg pastoral and agro-pastoral areas, conducted in seven regions of Ethiopia, indicates that, despite ongoing Humanitarian Food Assistance (HFA), an estimated 8.5 million people (21% of the 41 million people analysed) are highly acute food insecure in Crisis (IPC Phase 3) or higher between July and September 2020. Of these, about 7.1 million people were classified in Crisis (IPC Phase 3) and about 1.4 million people in Emergency (IPC Phase 4).\nBetween October and December 2020, Ethiopia’s food security situation is likely to improve slightly due to the seasonal (Meher) harvests. However, below-average Belg season production, due to desert locust infestation, poor rainfall performance in localized areas, conflict & climate-induced displacement and high food prices fueled by the COVID-19 pandemic, will likely result in around 6.7 million people in Crisis (IPC Phase 3) or higher, despite planned and funded humanitarian response.\nBetween January and June 2021, households relying on pastoral livelihoods typically depend on markets for food during this period. With food inflation at around 24% in July 2020, prices are expected to remain higher than previous years during the lean season, affecting market access. While safety nets are expected during this period, the analysis could not include HFA because it is yet to be planned. About 11.1 million people are expected to be in Crisis (IPC Phase 3) or higher.\nKey Drivers\nJoin our mailing list", "pred_label": "__label__POS", "pred_score_pos": 0.9555469751358032}
{"content": "Over time, the well-being of Calgary and area’s Indigenous population has been negatively impacted by political, social, and economic policies and practices, resulting in suppressed Indigenous culture, identity, and spirituality. This has created trauma spanning multiple generations, creating serious repercussions for Indigenous people and limiting the inclusivity of the place we call home.\nOur city thrives when Indigenous people and their culture are acknowledged, celebrated, and included in the growth and development of our communities. That’s why the Natoo’si Indigenous Healing and Well-being Initiative emerged in mid-2015—to address intergenerational trauma as a root cause of the challenges many Indigenous people in our city face. The programs supported through this initiative offer comprehensive healing approaches that strengthen Indigenous cultural identity and engage individuals and families on a healing path.", "pred_label": "__label__POS", "pred_score_pos": 0.9997547268867493}
{"content": "Purchase/rental options available:\nUsing longitudinal data from the Wabash National Study of Liberal Arts Education, our findings suggest that first-generation students are at a significant disadvantage across cognitive and psychosocial outcomes compared to students whose parents have at least some postsecondary education. Furthermore, we tested for the conditional effects of good practices on first-year outcomes and found that effects of good practices on both cognitive and psychosocial outcomes differed in magnitude, and sometimes in direction, for first-generation versus non-first-generation students.", "pred_label": "__label__POS", "pred_score_pos": 0.9990076422691345}
{"content": "Research output: Contribution to journal/Conference contribution in journal/Contribution to newspaper › Journal article › Research › peer-review\nAims and objectives: To explore nurse–patient interactions in relation to the mobilisation of nonsedated and awake, mechanically ventilated patients in the intensive care unit. Background: Lighter sedation has enabled the early mobilisation of mechanically ventilated patients, but little is known about the nurses' role and interaction with critically ill patients in relation to mobilisation. Design and methods: The study had a qualitative design using an ethnographic approach within the methodology of interpretive description. Data were generated in two intensive care units in Denmark, where a strategy of no sedation was applied. Participant observation was conducted during 58 nurse–patient interactions in relation to mobilisation between nurses (n = 44) and mechanically ventilated patients (n = 25). We conducted interviews with nurses (n = 16) and patients (n = 13) who had been mechanically ventilated for at least 3 days. The data were analysed using inductive, thematic analysis. The report of the study adhered to the COREQ checklist. Finding: We identified three themes: “Diverging perspectives on mobilisation” showed that nurses had a long-term and treatment-oriented perspective on mobilisation, while patients had a short-term perspective and regarded mobilisation as overwhelming in their present situation. “Negotiation about mobilisation” demonstrated how patients actively negotiated the terms of mobilisation with the nurse. “Inducing hope through mobilisation” captured how nurses encouraged mobilisation by integrating aspects of the patient's daily life as a way to instil hope for the future. Conclusions: Exploring the nurse–patient interactions illustrated that mobilisation is more than physical activity. Mobilisation is accomplished through nurse–patient collaborations as a negotiated, complex and meaningful achievement, which is driven by the logic of care, leading to hope for the future. Relevance to clinical practice: The study demonstrated the important role of nurses in achieving mobilisation in collaboration and through negotiation with mechanically ventilated patients in the intensive care unit.\nOriginal language English Journal Journal of Clinical Nursing Volume 28 Issue 11-12 Pages (from-to) 2329-2339 Number of pages 11 ISSN 0962-1067 DOIs Publication status Published - 2019\nID: 127850752", "pred_label": "__label__POS", "pred_score_pos": 0.7260178923606873}
{"content": "We often talk about the importance of planning for pregnancy. In these discussions, we emphasize the importance of supplementation with folic acid as a means of decreasing risk for birth defects and improving neurodevelopmental outcomes in children. A recent study indicates that adequate levels of iron may also play an important role in fetal brain development and that children born to mothers with anemia during pregnancy may have worse neurodevelopmental outcomes.\nUsing data from the Stockholm Youth Cohort, Swedish researchers evaluated 532,232 children born between January 1, 1987 and December 31, 2010, with follow-up of the children in health registers through 2016. They looked at the association between anemia in the mother (recorded at ? 30 weeks or > 30 weeks) and risk for autism spectrum disorder (ASD), attention-deficit/hyperactivity disorder (ADHD) and intellectual disability (ID) in their children.\nASD, ADHD, and ID were more commonly reported among children born to mothers with anemia within the first 30 weeks of pregnancy compared with mothers diagnosed with anemia later in pregnancy (4.9% vs. 3.8% for ASD, 9.3% vs. 7.2% for ADHD, 3.1% vs.1.1% for ID). The results were similar when women with anemia were compared to mothers without anemia (4.9% vs. 3.5% for ASD, 9.3% vs. 7.1% for ADHD, 3.1% vs.1.3% for ID).\nAfter controlling for potential confounders, researchers observed that anemia diagnosed during the first 30 weeks of pregnancy but not later was associated with increased risk of diagnosis of ASD (odds ratio [OR], 1.44; 95% CI, 1.13-1.84), ADHD (OR, 1.37; 95% CI, 1.14-1.64), and ID (OR, 2.20; 95% CI, 1.61-3.01). While the risk of these disorders is elevated, it is important to note that the absolute increase in risk is relatively small.\nAlthough maternal anemia may be associated with other factors associated with worse neurodevelopmental outcomes (i.e., malnutrition, inadequate prenatal care, poor adherence to prenatal vitamins), the researchers attempted to control for these factors. They hypothesize that iron deficiency anemia disrupts fetal brain development, noting that iron is essential for processes including myelination, dendrite arborization, and synthesis of monoamine neurotransmitters.\nGiven the prevalence of anemia in women of childbearing age, this study underscores the importance of consistent prenatal care and the usage of prenatal vitamins containing iron. It should be noted that not all prenatal vitamins contain the US recommended daily allowance (RDA) of iron (27 mg/day). Some women, including African-American women, vegetarians, and those with intestinal disorders and other chronic illnesses, are at higher risk for iron-deficiency anemia and should talk to their physician about iron supplementation during pregnancy,\nRuta Nonacs, MD PhD\nAssociation of Prenatal Maternal Anemia With Neurodevelopmental Disorders.\nWiegersma AM, Dalman C, Lee BK, Karlsson H, Gardner RM. JAMA Psychiatry. 2019 Sep 18:1-12.\nDoes maternal anemia affect fetal neurodevelopment? (Contemporary OB/GYN)\nAnemia in Early Pregnancy Linked to Autism, ADHD, Intellectual Disability in Kids (Medscape – free subscription)\nCould Mom’s Anemia Hurt Baby’s Brain? (Medpage Today)\nTags:", "pred_label": "__label__POS", "pred_score_pos": 0.5615813136100769}
{"content": "Nitric Oxide Ultra (Pure Encapsulations) SKU:\nNitric oxide expands the blood vessels, increasing blood flow and decreasing plaque growth and blood clotting. Viagra and other drugs like it, reduce erectile dysfunction by working on the nitric oxide pathway.\nHealthy Blood Flow: Nitric Oxide Ultra offers a unique blend of cranberry and grape seed extracts combined with citrulline to support blood flow. These well-researched extracts blend to support nitric oxide production and healthy blood flow. Provides Antioxidants: Nitric Oxide Ultra contains CranLoad, which delivers a unique cranberry and grape seed blend that has been the subject of several trials. Vascular Support: Nitric Oxide Ultra contains CranLoad to offer vascular support, as well as heavy flow-mediated dilation.\nTaurine is included for its multifaceted vascular support properties. Research suggests that taurine promotes vascular cell health, cytokine balance, and nitric oxide production. In a randomised, double-blind, crossover trial, supplementation with taurine for two weeks promoted arterial flexibility and flow-mediated dilation.\nMagnesium promotes healthy blood flow by supporting nitric oxide production, calcium channel activity and endothelial function.\nAscorbic acid is included to enhance nitric oxide activity and provide blood vessel endothelial antioxidant protection.", "pred_label": "__label__POS", "pred_score_pos": 0.9988559484481812}
{"content": "PTSD can occur after experiencing or witnessing a traumatic event, but symptoms must be present for months or years. Therapy can help with identifying and managing triggers.\nPost-traumatic stress disorder (PTSD) is a psychiatric disorder that can affect people who have experienced or witnessed a traumatic event. Such triggering events may include war/combat, rape or other physical abuse, natural diasters, terrorist acts, or a serious accident. Common symptoms include nightmares, severe anxiety, flashbacks of the event, and uncomfortable thoughts. It is normal and expected for people who experience a traumatic event to have temporary symptoms that improve with time. However, PTSD may be diagnosed when symptoms persist for months or even years, worsen over time, and if normal everyday functioning is impacted. Additional conditions may accompany PTSD, such as depression, substance use, memory problems and other mental health and physical problems.\nTREATMENT\nMore than three million people are diagnosed with PTSD in the U.S. every year and women are twice as likely to suffer from PTSD than men. Treatment has proven effective in reducing symptoms and improving function, and can include psychotherapy and medication, such as antidepressants, to manage symptoms. Talk therapy may include educating the patient on their symptoms, and helping identify what triggers symptoms as well as teaching skills to manage them.", "pred_label": "__label__POS", "pred_score_pos": 0.546135663986206}
{"content": "The Thang Long Entrepreneur Gala 2020, an annual event to honor outstanding enterprises and entrepreneurs in Hanoi, is set to take place on October 24 at the Hanoi Opera House, according to the Hanoi Association of Small and Medium Enterprises (Hanoisme).\nThe Thang Long Entrepreneur Gala 2019.\nThe Gala is part of a number of events celebrating the upcoming 13th national Party Congress, the successful conclusion of Hanoi’s 17th Party Congress, Hanoi’s Liberation Day (October 10), the 1,010th anniversary of Thang Long – Hanoi, and 25th anniversary of the establishment of Hanoisme.\nThis year, over 200 enterprises representing nearly 290,000 from Hanoi’s business community would be recognized by leaders of the government and the city for their outstanding contributions to the process of socio-economic development.\nThe ceremony also offers an opportunity for enterprises to discuss business strategies and measures for sustainable development.\nIn the January – September period, nearly 20,000 enterprises were established in Hanoi with a combined registered capital of VND260.8 trillion (US$11.28 billion).\nThis year, Hanoi targets 30,000 newly established enterprises, representing an 11% increase from 27,000 in the previous year, which remains one of the city’s main priorities set by the Hanoi People’s Committee for rest of the year.", "pred_label": "__label__POS", "pred_score_pos": 0.9973843097686768}
{"content": "Education: Institutions are facing multiple challenges\nIn every market, they are expected to embrace new technologies, respond to changing consumer preferences, and manage increasing globalization—while delivering better student outcomes. Is it possible to navigate these often competing demands while fulfilling their core missions?\nMarket entry strategy\nWide range of options exists for companies to enter a new market and to develop successful long-term presence.", "pred_label": "__label__POS", "pred_score_pos": 0.9995061755180359}
{"content": "This object is in collection Description Abstract: The study of civic engagement is complex and continues to evolve. Desired outcomes of civic engagement are well-framed within the Positive Youth Development (PYD) perspective, a strength-based approach to understanding youth development derived from relational developmental systems theory (RDST). However, less is known about the psychological identity processes that might lead to civic e... read more", "pred_label": "__label__POS", "pred_score_pos": 0.8313832879066467}
{"content": "Project ARTiculate is an arts integrated cross-curricular mural program developed by Side x Side to strategically serve youth across all three Portland middle schools during a pivotal developmental time. Creating site-based murals provides an opportunity for students to acquire and demonstrate the 21st Century skills of collaboration, creativity, and critical thinking while addressing core content, leadership, student empowerment, and school culture. This program was funded through generous grants from the Lennox, Horizon, and Cabin Foundations and made possible by Side x Side teaching artists Laurie Downey and Ryan Adams.\nDuring the 2019-2020 school year, seventh graders at King Middle School collaborated with Side x Side teaching artist Laurie Downey to create a mural during a “Pathway to the Plate and Beyond” expedition. Using Project Journals to gather written and visual information, students conducted research on how we grow and transport food. They met with local organizations involved in food security, composting, and community gardens to follow food beyond the plate, and conducted an extensive study of plate waste at their school. Each student contributed to the mural by transferring research, drawings, and text onto the mural panels, resulting in an informative art piece installed in the cafeteria that addresses our food systems, consumption, and waste.\nEighth graders at Lyman Moore Middle School participated in a mural program addressing the questions, “Who am I? Who are we?” Students used writing, poetry, and design to explore what it means to be an individual and a member of the school community. Led by Side x Side teaching artist Ryan Adams, students learned about street art and community engagement. Combining the expertise of a professional artist with class comments, public messaging, and creative writing, they produced a collaborative mural for the entryway of the school illustrating the culture and inclusivity at Lyman Moore Middle School, a welcoming legacy by the eighth grade class.\nSeventh graders at Lincoln Middle School participated in a program led by Side x Side teaching artist Laurie Downey, integrating art into their science unit. Students used Project Journals, a method of visual research, to record data on species diversity in birds, arthropods, and mollusks. They learned key observational drawing techniques while using local taxidermy mounts on loan from Maine Audubon highlighting necessary survival adaptations. Although disrupted by the Covid-19 coronavirus pandemic and resulting school closures, Laurie Downey was able to pivot to remote learning by creating digital mock-ups for the mural using student journal entries.", "pred_label": "__label__POS", "pred_score_pos": 0.8193705081939697}
{"content": "Abstract\nThe Lusi mud eruption in East Java continues unabated after more than a decade of activity as a pulsating geyser system bursting mud, clasts, water, and gas. The origin of the fluids and their properties at depth are not well constrained, thus hampering our understanding and modelling of the system. Previous geochemical and geophysical studies show that Lusi is a sediment-hosted hydrothermal system with two sources of mud at depths between 0.3-2 km and another between 3.5-4.75 km. Here, we present results of mineral thermometry using Raman spectroscopy and chlorite composition on clasts erupted at Lusi. The results show that some of these specimens originate from the two main fluid sources, and at depths consistent with the geochemical and geophysical interpretation. Two main clast lithotypes erupt at Lusi. The first lithotype is a light grey shale returned to the surface from the Upper Kalibeng Formation (the primary mud source) and equilibrated at temperatures below 200 °C. The second lithotype is a black shale, whose source is the Ngimbang Formation at >3800 m depth. Two distinct temperature clusters are recorded in these black shales: one at 179 ± 17 °C, consistent with the temperature estimate at 3800 m depth with the pre-eruption geothermal gradient, while younger minerals in the same specimen recorded substantial anomalous heating at ∼250 °C. These high temperatures indicate interaction with a heat source associated with the eruption through mixing with hydrothermal fluids. This temperature jump suggests rapid heating at ∼4000 m depth, consistent with a scenario of a magmatic intrusion and hydrothermal fluids circulation. This rapid and significant temperature increase would initiate devolatilisation reactions of hydrous minerals within the deep sedimentary package and generate substantial (highly overpressured) fluids at depths significantly below the main source of erupted mud. We infer that reactive and thermal pressurisation led to a deep and metastable system susceptible to e.g. seismic activity ultimately opening fluid pathways towards the surface along the Watukosek fault system. The two temperatures clusters recorded in the clasts show that conductive heat flow was the dominant heat transport prior to the eruption, while the system is now driven by large-scale convection and advective heat transport. The Lusi eruption occurred in a highly populated area forcing the evacuation of several tens of thousands of people. This system appears unstoppable and poses a real and present hazard for the settlements still surrounding the eruption site. Continuous research is necessary to understand this spectacular phenomenon, both for its important scientific relevance, and the societal impact of this natural disaster.", "pred_label": "__label__POS", "pred_score_pos": 0.5235785841941833}
{"content": "Explore the measures used to assess diverse aspects of cognition within and across five British birth cohort studies\nThis guide was created as part of CLOSER Work Package 19: Assessment and harmonisation of cognitive measures in British birth cohorts.\nIntroduction Explore the measures by life stage Explore the measures by cohort study 1946 National Survey of Health and Development (NSHD) 1958 National Child Development Study (NCDS) 1970 British Cohort Study (BCS70) Avon Longitudinal Study of Parents and Children (ALSPAC) Millennium Cohort Study (MCS) Further information Acknowledgements and copyright information for this guide References for this guide Download the full guide as a PDF\nNote the information in this guide is valid as of January 2020.\nTo cite the guide, please use the following suggested citation:\nMoulton, V., McElroy, E., Richards, M., Fitzsimons, E., Northstone, K., Conti, G., Ploubidis, G.B., Sullivan, A., & O’Neill, D. (2020). A guide to the cognitive measures in five British birth cohort studies. London, UK: CLOSER.", "pred_label": "__label__POS", "pred_score_pos": 0.9545838832855225}
{"content": "Review of Research on Conveying Risk Information Presented During the Informed Consent Process\nAUTHOR/FUNDING INFORMATION:\nDr. Rector is part of the HSR&D Center for Chronic Disease Outcomes Research in Minneapolis.\nBACKGROUND:\nA significant concern in research ethics is whether prospective research participants are given adequate information about the potential risks of research participation during the informed consent process. Moreover, words commonly used in the process may be ambiguous. Words such as “rarely” and “possible” are used to describe the possibility that participants might experience adverse effects during the study intervention; however these words are open to interpretation. One study indicated that patients thought “rare” deaths would be significantly less likely than “rare” pneumonia following surgery. Other studies raise concerns about people’s ability to comprehend numbers. For example, a survey of older female veterans showed that nearly half could not convert 1% to 10 in 1000. The author reviews several studies to assess whether or not informed consent language adequately communicates risk to participants.\nFINDINGS:\nWhether numeric or word formats lead to better decisions about participation in research is largely unknown. A few small studies indicate that using numbers rather than words to communicate the likelihood of adverse outcomes can make a difference, and suggest that many people prefer the chances of adverse effects be expressed in numerical terms.\nThe author recommends minimizing probabilistic words (e.g., “rarely,” “possible”) and encourages the use of simple frequencies with common denominators (e.g., “one out of 100 people”).\nThe findings from this review are insufficient to formulate guidance but confirm the need for additional research on conveying risk information to study participants during the informed consent process.\nRector, T. How Should We Communicate the Likelihood of Risks to Inform Decisions about Consent? IRB: Ethics & Human Research July-August 2008;30(4):15-18.", "pred_label": "__label__POS", "pred_score_pos": 0.5038994550704956}
{"content": "Credit Points\nDuring their studies, students must accrue a total of 30 credit points (CPs), with one CP being equivalent to the European Credit Transfer and Accumulation System (ECTS) credit point. One ECTS corresponds to approximately 30 working hours including preparation. CPs are earned for each of the three mandatory Thesis Advisory Committee meetings. Further, a combination of required and optional courses allows students to assemble a curriculum according to their needs and Thesis Advisory Committee’s recommendations.\nStudents will be informed about the course’s requirements and assignments, whether they will be required to take an exam (and if so, written or oral), present a seminar or submit a final paper. The program’s spokesperson and coordinator decide on the number of CPs awarded for each course. Each year, the spokesperson and coordinator may revise this, however once a student has received a grade in a course, the number of CPs can not change.\nCPs from partnering Institutions CPs for courses and workshops\nThe IMPRS‑TP encourages students to participate in international courses and workshops. Students should apply in advance to the program coordinator for CP assessment of external courses. The application should include all relevant information, such as the institution and lecturer, the number of hours, the course syllabus, and the mode of grading. Approval and the number of CPs awarded are at the discretion of the IMPRS‑TP spokesperson and coordinator.\nCPs for additional extracurricular activities\nThe credit-based system also encourages student contribution. CPs can be awarded for teaching (e.g. organizing a method workshop), project management (e.g. organizing a symposium like the Munich <interact>) or leadership activities (e.g. serving as student representative). Finally, CPs will be awarded for additional curricular activities, such as the participation in transferable skill courses, advanced method training or active participation at scientific conferences.", "pred_label": "__label__POS", "pred_score_pos": 0.6480785012245178}
{"content": "Defending Misconduct or Unethical Conduct Complaints Before the Missouri Committee for Social Workers\nMissouri licensed social workers often face complaints related to alleged misconduct or violation(s) of regulations governing ethical or moral standards, client relationships, and relationships with colleagues. These complaints may, for example, include allegations of an improper sexual relationship or unlawful financial practices. To defend against such complaints, an attorney must have familiarity with the realities and challenges of social work and applicable Missouri regulations. If you receive a complaint alleging you engaged in misconduct or unethical practice as a licensed social worker in Missouri, contact Dolley Law, LLC today.\nDefending Licensed Social Workers Against Allegations of Unethical Conduct\nUnethical conduct has a specific meaning under Missouri law. Under Section 337.630 RSMo, Missouri licensed social workers must adhere to the ethical standards adopted by the Division of Professional Registration. These standards are codified in the Code of State Regulations and specifically govern the conduct of social workers. Additional ethical and professional standards also apply to licensed social workers and may provide cause for discipline under separate areas of Missouri law. When faced with an allegation of unethical conduct, it is important to contact an attorney with the necessary background and experience as soon as possible. These cases often involve complicated statutes, regulations and standards that are difficult to navigate. The attorneys at Dolley Law, LLC have significant experience representing licensed professionals accused of unethical conduct or misconduct and will provide legal representation to protect your license and professional reputation.\nMissouri Committee for Social Workers Standards in Unethical Conduct Cases\nMissouri licensed social workers may be disciplined for unethical conduct or misconduct, which may include:\nEngaging in activity that exploits clients, students or supervisees; Engaging in sexual intimacies with a client, student, or supervisee; Failure to report known or suspected violations of social work statutes or regulations; Entering or continuing a social, business, or sexual relationship with a current or former client; Conflicts of interest; Failure to disclose purposes, goals, techniques, rules and limitations that may affect a professional relationship at the time it begins; Undertaking or continuing a professional relationship when the social worker’s competency or objectivity is impaired; Providing professional services one is not qualified to provide; Failure to inform clients about electronic recording of sessions; Failure to terminate a professional relationship when required to do so; Failure to protect clients against physical threats, intimidation, or coercion; Failure to maintain required records; Knowingly causing a client to terminate a relationship with another social worker for professional gain; Engaging in sexual intimacies with a colleague over whom the social worker exercises professional authority; Failure to exercise appropriate supervision, working conditions, evaluations, consultation, or experience; Using a professional relationship for personal gain or profit; Giving a commission or rebate for referrals; Accepting compensation from anyone other than the client without disclosure; Charging an unreasonable fee; Accepting remuneration for services that exploits the professional relationship; or Failure to maintain client confidentiality.\nLicensed social workers may face discipline for conduct that violates these specific regulations related to professional responsibility. Alternatively, the Committee may seek discipline under another area of Missouri law, such as misconduct, fraud, misrepresentation, dishonesty, or violation of a professional trust.\nWhen a complaint is filed with the Committee, it initially proceeds through the investigative process. This may require a written response to the complaint, responding to the Committee’s document requests, participating in an interview with an investigator, and possibly a meeting with the Committee.\nComplaints about misconduct or unethical conduct frequently involve sensitive personal or financial information. Social workers may be asked to produce financial records, personal communications, or client records. They may also be asked to publicly discuss and answer questions about intimate relationships and emotional, difficult professional relationships. Social workers in this situation often do not understand their rights, how to effectively respond to these allegations, or how to publicly discuss these matters. Social workers also need to understand how their statements, records and communications affect their case and how Missouri statutes and regulations apply to the specific facts at issue. Our Firm’s attorneys will represent you during each stage of the investigation and develop a comprehensive strategy designed to effectively protect your rights, career, and reputation.\nComplaints that are not dismissed after investigation enter the litigation process. The Committee may propose public discipline through a settlement agreement or may file a complaint with the Administrative Hearing Commission (“AHC”), which may ultimately result in a trial-type hearing. Social workers accused of unethical conduct or misconduct have the right to see the evidence against them, testify on their own behalf, call witnesses, and present evidence. If a social worker successfully defends against the Committee’s allegations, the case ends with a finding that he or she is not subject to discipline.\nIf a social worker is found subject to discipline, a second hearing is held before the Committee. Dolley Law, LLC represents clients in these disciplinary hearings and presents mitigating evidence and legal arguments on their behalf. The Firm’s attorneys also counsel and advise clients on settlement agreement terms and the appropriate course of action for each case.\nContact Us\nIf you are notified that a complaint about misconduct or unethical conduct has been made against your Missouri social worker license, contact Dolley Law, LLC to obtain experienced legal counsel to address the situation by calling (314) 645-4100 or by email at kevin@dolleylaw.com.", "pred_label": "__label__POS", "pred_score_pos": 0.7487013339996338}
{"content": "Sometimes when an accident occurs, it’s because of unpredictable circumstances beyond our control. However, sometimes tragedies occur because of the negligence of parties who have a responsibility to make public areas safe for passing pedestrians. These individuals may be held accountable for their actions through a New Hampshire personal injury lawsuit. In order to explain a complex accident situation to a jury, an expert witness is often needed during a trial. Unfortunately, plaintiff’s are frequently prevented from presenting compelling expert witness testimony.\nIn a recent First Circuit appellate opinion, a plaintiff was struck by a car while working in a construction zone. While attempting to cross the street after grabbing dinner, the plaintiff was standing on the roadway’s divider when traffic suddenly rushed towards him from both directions. The change in traffic trapped the plaintiff on the divider, where he was subsequently struck head-on by a westbound SUV. As a result of the accident, the plaintiff has become quadriplegic and will require extensive medical care for the rest of his life.\nFollowing his accident, the plaintiff filed a negligent-design lawsuit against several entities responsible for the construction project that laid the backdrop for his injuries. He also retained a single expert to testify on the standard of care that these entities owed to pedestrians in construction affected areas. Through this expert’s testimony, the plaintiff hoped that he would be able to successfully establish his claim that the defendants’ negligence caused the accident to occur. The evidence that was going to be provided through the expert’s testimony was crucial to the plaintiff’s claim.", "pred_label": "__label__POS", "pred_score_pos": 0.7284006476402283}
{"content": "The purpose of this study was to characterize the epileptogenicity of tubers and surrounding cortex in patients with tuberous sclerosis complex (TSC). Three pediatric patients with TSC and intractable epilepsy underwent surgical resection of tubers associated with epileptogenic foci. In all patients, presurgical imaging revealed a prominent tuber that correlated on electroencephalography (EEG) with frequent interictal epileptiform discharges and electrographic seizures. Intracranial electrocorticography (ECoG) was performed using subdural grids placed over the tuber and surrounding cortex and depth electrodes positioned directly within the tuber. In all three patients, the depth electrode within the tuber was electrographically silent, whereas the surrounding cortical tissue showed significant epileptiform activity. The tuber and the electrically active adjacent cortex were resected. The patients experienced a drastic reduction in seizure frequency postsurgery. Epileptogenicity of cortical tubers may derive not from the lesion itself, but rather from the perturbation or abnormal development of the surrounding cortex.", "pred_label": "__label__POS", "pred_score_pos": 0.9393492937088013}
{"content": "Abstract\nThe structure and primary devitrification process of the melt-spun Cu\n60(Zr or Hf) 30Ti 10 alloys were investigated. It was confirmed that the compositional segregation in the diameter range of 5-10 nm exists in the as-quenched state. The nanocrystalline particles with cubic structure are observed in the glassy matrix in the high-resolution transmission electron microscopy images, of which size is corresponding to the scale of compositional segregation. Small-angle X-ray scattering measurement also indicates the development of nanoscale inhomogeneity with the same size as that of nanocrystalline particles. The nanocrystalline region has high Cu content. In contrast, Zr or Hf and Ti elements are enriched in the glassy region. These results are recognized as the formation of novel structure consisting of the glassy and nanocrystalline phases. It is suggested that the precipitation of bcc CuZr phase as a primary crystallization phase proceeds in the glassy phase remaining the nanocrystalline phase in the Cu-Zr-Ti alloy. Meanwhile, the glassy and nanocrystalline phases are transformed to an orthorhombic Cu 8Hf 3 phase at the initial crystallization stage in the Cu-Hf-Ti alloy. These differences of crystallization process are consistent with the results of thermodynamic and kinetic analyses of the transformation mode. Keywords Crystallization Cu-based metallic glass Kinetics Nanocrystal Nanostructure Transformation ASJC Scopus subject areas Materials Science(all)", "pred_label": "__label__POS", "pred_score_pos": 0.9032158851623535}
{"content": "Selecting the right fragrances for your scented oil diffuser can seem like a challenge. There are so many options to choose from, and how can you be certain you’ll\nCategories Category: Diffusers\nFragrance is a wonderful way to make your house feel more relaxing and welcoming. However, there are hundreds of ways to bring scent into your home, and not all\nWouldn’t it be nice to infuse your whole home with an aroma that instantly makes you feel warm and content as soon as you walk through the front door?\nAre you ready to embrace a totally new home atmosphere? Your sense of smell is a powerful sense that connects you with cherished memories and peaceful thoughts. Explore the\nFill your home with calming, invigorating, or inspirational scents with a home fragrance diffuser. Unlike a room diffuser, these whole-home devices allow you to connect to your air ductwork\nEveryone enjoys a home that smells clean and inviting, but using candles, multiple diffusers and sprays can take up precious space in your home. These items can also be\nLooking for a way to freshen up your home and enjoy some of the benefits of essential oils? Discover how an air diffuser and essential oils work to see\nTired of changing fragrances throughout your home? An oil diffuser is an excellent way to freshen up your environment, but most can only affect the aroma in a single\nWith the growing interest in essential oils, many people have begun to rely less on traditional candles and scent sprays and to invest instead in a home fragrance diffuser\nA delightful fragrance transforms a house into a home. Consumer-grade fragrance products often involve risks, such as burning candles or using scents that contain substances you do not want", "pred_label": "__label__POS", "pred_score_pos": 0.6510106325149536}
{"content": "This brief essay explores a key but often overlooked hurdle to using blockchain solutions, which is the complexity that decentralized solutions necessarily introduce. At times, the benefits of such solutions appear to exceed the added cost of complexity but often they do not. With this tradeoff in mind, the paper considers two use cases, digital ID and health supply chain management.\nOur Work\nWith rigorous economic research and practical policy solutions, we focus on the issues and institutions that are critical to global development. Explore our core themes and topics to learn more about our work.", "pred_label": "__label__POS", "pred_score_pos": 0.9998847842216492}
{"content": "Incorporating coronary CT angiography (CCTA) into the initial evaluation of low-risk patients coming to hospital emergency departments (EDs) with chest pain appears to reduce the time patients spend in the hospital without incurring additional costs or exposing patients to significant risks. The report of a study conducted at nine U.S. hospitals appears in the July 26 New England Journal of Medicine.", "pred_label": "__label__POS", "pred_score_pos": 0.819896936416626}
{"content": "This Fact Sheet explores telematics jamming and provides organisations with guidance on how to identify and manage this risk. Why does this matter?\nThe capacity for employees, contractors, consigners, insurers, to name a few, to monitor the safe movement of their vehicles and goods has been achieved through telematics, also known as In-vehicle Monitoring Systems (IVMS). Alongside the increased usage of telematics has been the emergence of ‘jamming tools’ which actively block the signal to / from the device. Anecdotally, this appears to be a growing issue in the United Kingdom where businesses with fleets have begun to be alerted to their use through discussions with their peers. Nick Croft from Road Safety Support has been championing awareness of IVMS jamming in the United Kingdom and was questioning the awareness and preparedness of Australian fleet managers.\nWhat is telematics?\nTelematics systems offer opportunities to reduce accidents involving heavy vehicles by improving driver performance through tracking a vehicle’s operation through a combination of GPS, sensors within the vehicle and interaction with a vehicle’s onboard computer based on organisational and operational requirements. Comparisons can then be made against performance parameters as set by the organisation.", "pred_label": "__label__POS", "pred_score_pos": 0.9227882623672485}
{"content": "The Chakras and Mental Health\nAs you might know, Ayurveda recognizes 114 chakras—or energy centers—within the body. Of these 114, there are seven primary chakras, located throughout the head and spinal column.\nOne good way to conceptualize these is that they’re places where the mind-body connection manifests as our physical sensations and feelings intertwine. For example, we experience sexual feelings in our sacral center, and we feel love from our heart, and we sense a connection to the universe from the crown of our head.\nWhen it comes to negative emotions, anxiety typically stems from the root chakra, which resides at the base of our spine. This is due to the fact that this area represents our stability and grounding in the world. If we aren’t properly grounded, fear and anxiety can easily overtake us. The root chakra can be balanced by enjoying the color red, sitting on the floor, walking barefoot on the earth, and immersing yourself in water.\nOn the opposite polarity, our crown chakra, which lies at the top of our heads, can be responsible for feelings of depression. This energy center regulates our connection to our highest self and even the divine. When it is functioning properly, we feel connected, intuitive, and guided in all that we do. Inspiration and creativity also stem from this center. However, when this area is not working, we can feel cut-off from the light of the world, uninspired, directionless, and depressed. Some great ways to reactivate the crown chakra include practicing meditation, selfless service, and self-love through healthy self-care routines.", "pred_label": "__label__POS", "pred_score_pos": 0.7851810455322266}
{"content": "First published in 1896, “In His Steps” written by Charles M. Sheldon has sold more than fifty million copies and is one of the best selling books of all time. The full title of the book is “In His Steps: What Would Jesus Do?” In recent years the book spawned the W.W.J.D. bracelet which became a popular reminder when being worn to simply ask in every situation faced, “what would Jesus do?” The primary “example” that Jesus left us was nothing less than His own sacrificial death!\n“For you have been called for this purpose, since Christ also suffered for you, leaving you an example for you to follow in His steps.” (1 Peter 2:21 NASB)\nW.W.J.D.\nNote the context: “For this finds favor (also the same word for “grace”), if it is for the sake of conscience toward God a person bears up under sorrow when suffering unjustly. For what credit is there if, when you sin and are harshly treated, you endure it with patience? But if when you do what is right and suffer for it you patiently endure it, this finds favor (grace) with God.” (1 Peter 2: 19 -20)\nTo follow Christ’s example is to be willing to endure unjustified suffering—even defamation and persecution—with grace and patience.\nBut that is not all; we must also do it with silence! “And while being reviled, He did not revile in return; while suffering, He uttered no threats.” (1 Peter 2:23) “And like a sheep that is silent before its shearers, so He did not open His mouth.” (Isaiah 53:7)\nIt is a natural reaction to want to strike back at one who has slandered or injured us. This is especially true if such an act was an insulting response to kindness. But such a “natural” reaction was not Christ’s reaction. He could have “called twelve legions of angels” (Matthew 26:53) to His defense, but He chose to suffer in silence.\nWhy Would Jesus Do This?\nWhy would He do such a thing? First, if he had not done so we would have been lost in our sins forever. He “bore our sins in His body on the cross.” (1 Peter 2:24)\nSecond, He left us an example that we should “follow in His steps.” He was not just silent in His sufferings; “He suffered for you!” If we would really be like Him, we must be willing to suffer quietly on behalf of others, even when they are the ones who deserve it. This is acceptable with God!", "pred_label": "__label__POS", "pred_score_pos": 0.808363139629364}
{"content": "A recent study has come to a rather definitive solution as it pertains to food waste in the manufacturing process. Thankfully, the same study was able to identify the cause and a potential solution.\nFirst, the study. In January 2019, researchers at Brunel University and Ghent University examined 47 food manufacturers in Belgium, attempting to find where the most food loss was found. When food waste occurred, almost 11% was due to human error. This reason was easily the highest cause of food waste.\nThe reasoning? According to the study, a lack of standardization, visual management or management supervision. A lack of set procedures or a standard of manufacturing led to this loss.\nIt’s also important to note that this food waste was not a small number: For every 35 tons of food produced, 1 ton was lost.\nThe Need For Training\nThe study identified numerous potential areas for both management and line production workers that can be potentially studied. These include:\nSetting and adhering to standard procedures. Identifying common errors and ways to prevent them. Correct ways to switch out products, also identified as a key issue when it came to food waste. Appropriate supervision tactics. Appropriate measurement of food waste.\nThe study also noted that this issue was particularly prevalent at many smaller manufacturers. Unfortunately, this makes sense, as it is very possible that many of these smaller firms are unaware of just how much food they are wasting and may not have access to the tools available which can better train workers.\nThankfully, the same study identified a possible solution to this issue: Increased management supervision and training within the food process.\nNumerous training modules already exist that would allow for this training to be conducted. E-learning and online training can be ideal for these situations, and particularly appropriate during the COVID-19 outbreak that has shut down large swaths of the world economy. Indeed, E-learning can be ideal for many of these training opportunities, providing that online training is followed up with practical demonstrations.\nThis type of training comes with numerous benefits. It can be done at any time, in any place, ensuring that typical barriers to training are removed. It can be done on a massive scale and for as many employees as a manufacturer chooses. It is also cost-effective and can be done for an employer’s entire workforce at the fraction of a cost of in-person training.\nAs we specialize in trusted e-learning solutions for the food industry, we can help reduce your food waste with effective e-learning. Please contact us.", "pred_label": "__label__POS", "pred_score_pos": 0.548098623752594}
{"content": "Create an Account - Increase your productivity, customize your experience, and engage in information you care about.\nAs an effort to keep sidewalks clear, the City of North Bend is reminding residents that garbage, recycling and yard waste containers should be placed curbside - not on sidewalks - on designated collection days, and landscaping should be trimmed to prevent encroachment on public sidewalks.\nCity Municipal Code requires cans be placed curbside. According to the City's Republic Services contract, 'curb' or 'curbside' is defined as \"that area of the homeowner's property five (5) feet of the public street or private road without blocking sidewalks, driveways or street parking.\" [Note: Exemptions can be made for those with physical constraints, unable to bring their garbage to the curbside.]\nAdditionally, per City code it is also individual property owners’ responsibility to maintain trees, shrubs and other landscaping from encroaching on Right of Ways, which includes sidewalks. Containers placed on sidewalks - especially in older neighborhoods with mature landscaping - limits space for pedestrians.\nRemember - proper garbage/recycling/yard waste can placement ensures your pickup is not missed and assists drivers in efficient and safe collection routes. Containers should be placed at least 2 feet apart and at least 3 feet from cars, trees or mailboxes, with the lids opening toward the street. Allow at least 14 feet of overhead clearance above the containers and place them as close to the curb as possible.\nThe City appreciates residents help to keep sidewalks clear, particularly while pandemic social distance guidelines are in place, and for compliance with ADA standards.\nFor more information on Republic Services in North Bend visit: www.republicservices.com/municipality/north-bend-wa", "pred_label": "__label__POS", "pred_score_pos": 0.9430476427078247}
{"content": "Abstract\nWe use a new hedge fund data set from a separate account platform to examine (1) how much of hedge fund return smoothing is due to main fund-specific factors, such as managerial reporting discretion and (2) the costs of removing hedge fund share restrictions. These accounts trade pari passu with matching hedge funds but feature thirdparty reporting and permissive share restrictions. We use these properties to estimate that 33% of reported smoothing is due to managerial reporting methods. The platform's fund-level liquidity is associated with a 1.7% performance reduction on an annual basis. Investor flows chase monthly past performance on the platform but not in the associated funds.\nAll Science Journal Classification (ASJC) codes Strategy and Management Management Science and Operations Research", "pred_label": "__label__POS", "pred_score_pos": 0.9702122807502747}
{"content": "There has been remarkable growth over the decade in the food processing industry with a multitude of companies and start-ups offering ready-to-eat and other processed food. Dr.Neema, who holds a master’s degree in biotechnology, developed a fascination towards food processing during her tenure with CFTRI, Mysore. As part of her dissertation she worked under Dr. S. Raghava Rao, Senior Scientist...\nYou do not have permission to view the full content of this resource. Log in or register now.", "pred_label": "__label__POS", "pred_score_pos": 0.7026337385177612}
{"content": "COVID-19 Fever Temperature Indicators\nOur feverline® liquid crystal technology has been used by hospitals to monitor patient temperature trends for over 20 years. A calculated offset is used to estimate the core body temperature compared to the forehead then, by establishing a “healthy” reading this can be compared with a current one and a trend established. Any increase in core body temperature is quickly indicated.\nAs the COVID-19 lock down is gradually lifted, regularly checking staff for potential fever is recommended. These products below will quickly allow staff to identify if their temperature rises above normal, allowing immediate action to be taken and helping reduce the risk to others in the workplace and at home.\nThese thermometers indicate temperature after just 15 seconds and are simple to use for anyone.\nReturn-to-work fever temperature monitoring for COVID-19\nALERT\nCORONAVIRUS – Companies provide their staff with personal Forehead Thermometers to check for fever –\nmore details", "pred_label": "__label__POS", "pred_score_pos": 0.8106703758239746}
{"content": "Abstract\nThis article uses data from the National Longitudinal Survey of Youth to examine the coresidence patterns of children and adult males during the first three years of a child's life, with special attention to the children of adolescent mothers. Overall, the most common experience was for the children to have an adult male present over the full period. However, there were differences by race and the mother's age when she gave birth. For example, 83 percent of white children and 47 percent of black children born to mothers aged 20 or older lived with an adult male during their entire early childhood, while three quarters of white children and fewer than one-third of black children born to mothers younger than 18 had a male present in their household over their first three years. Among both races, children of older mothers were significantly more likely than others to be born into a household where an adult male was present. The stability of male coresidence varied significantly by the mother's age among white children, but not among blacks. Overall, black children experienced more changes in male coresidence than whites. Finally, the likelihood that the adult male would be married to the mother was positively associated with white race and the age of the mother when she gave birth.\nASJC Scopus subject areas Public Health, Environmental and Occupational Health", "pred_label": "__label__POS", "pred_score_pos": 0.5698433518409729}
{"content": "The search found 4 results in 0.047 seconds.\nThis technical brief is one in a series addressing four young key populations. It is intended for policy-makers, donors, service-planners, service-providers and community-led organizations. This brief aims to catalyse and inform discussions about how best to provide health services, programmes and support for young MSM. …\nThis publication provides a background in the risks faced by populations especially vulnerable to HIV and AIDS. The document outlines strategies effective in prevention of HIV and AIDS among sex workers, men who have sex with other men, and injecting drug users. Programs described include peer education, comprehensive health services and quality of treatment, provider referral networks, and in-service training and sensitization.\nThis AIDSTAR-One technical brief provides a systematic global review and synthesis of practical approaches, program examples, and resources to support human rights as a core element of HIV programming for MSM. The brief complements and is aligned with other global and regional publications that have relevance to human rights, health programming, HIV, and MSM. This document gives an overview of U.S. …\nThe tools discussed were intended to be designed for, and implemented primarily in health care settings. However, caution was urged during the consultation meeting that those activities should not be disconnected from other strategies, social services, and outreach programs, but rather an integral part of them; and the Regional Consultation focused mainly on gay and other MSM as the points of reference for MSM communities. …", "pred_label": "__label__POS", "pred_score_pos": 0.8854387402534485}
{"content": "The Michigan House of Representatives’ Oversight Committee will take testimony Tuesday on two proposed changes to the state’s Open Meetings Act.\nHB 5193 clarifies that public bodies cannot go into closed session to discuss threatened litigation, only specific pending litigation qualifies for closure under the law. HB 5194 specifies that public bodies who willful violate the OMA and then re-vote on their actions to validate them cannot use their subsequent compliance with the law as a defense in a criminal action against them.\nThe Michigan Coalition for Open Government, a tax-exempt nonprofit corporation, supports the proposed changes to the state Open Meetings Law.\nThe two bills would result in modest though needed modifications allowing the public access that has, at times knowingly or unwittingly, been circumvented by public bodies. Both bill were introduced by State Rep. Tom McMillin (R-45) who also chairs the Oversight Committee.\nThe hearing is scheduled for 2:30 p.m., in the Anderson House Office Building, R. 326, 124 N. Capitol Ave in Lansing.", "pred_label": "__label__POS", "pred_score_pos": 0.8668263554573059}
{"content": "receive a parcel\nHello! I am inviting you into my kitchen from your own to share food, thoughts, memories and time.\nI am engaging in a practice-as-research project exploring the relationships between food, bodies and care. Discourses around food and bodies can be fraught with many cultural anxieties. This project aims to shift the focus to discuss cooking/eating/feeding as social practices of kindness, love and care. Indeed, food is shared by families, friends, lovers, colleagues, classmates and strangers in restaurants, cafes, dining halls, break rooms, dining rooms and kitchens. Now, I would like to share it with you - through the post!\nI would like to send you ingredients with a note describing a meal and how to prepare it. They would come with a stamped envelope for you to return your thoughts and describe a meal you would make for someone you care about. I would like to make and eat that meal and I would like to share this publicly through videos.\nIf you are interested in participating in this exchange of care please fill in this form:\nThis research project is being conducted as part of MA Performance Practice as Research at The Royal Central School of Speech and Drama. Sensitive data collected for this project will be anonymised and stored for the current academic year and then six years further in compliance with the Data Protection Act 1998 as outlined in Section 2.9 of RCSSD's Research Ethics and Integrity Handbook 2019/20.\nDue to international shipping laws I am only able to send food within the United Kingdom. If you are interested but located elsewhere, please drop me an email and we can talk. Please let me how I can accommodate any additional access needs.", "pred_label": "__label__POS", "pred_score_pos": 0.8889034390449524}
{"content": "08 November 2013 #Employment\nThe government has published the draft Collective Redundancies and Transfer of Undertakings (Protection of Employment) (Amendment) Regulations 2013. The draft regulations reflect the government`s response to the consultation on proposed changes to TUPE, which was published in September 2013.\nThe draft regulations will be laid before Parliament in December and are expected to come into force in January 2014. We will keep you up to date on that. The majority of the amendments will apply to transfers which take place on or after that date. However, transitional provisions will apply in relation to the change in the time limit for providing employee liability information and the relaxation of the information and consultation obligations for micro businesses.\nThe big surprise was the government’s decision not to proceed with its initial plan to remove the rules on service provision changes, making the amendments far less significant than had previously been expected. We will be reviewing the changes in detail on Employmentbuddy next month.", "pred_label": "__label__POS", "pred_score_pos": 0.628053605556488}
{"content": "The GDPR is a recently introduced EU regulation that brought sweeping changes to the handling of personal data throughout Europe. Consisting of six data protection principles that all\nHealthcare businesses are subject to GDPR principles, with strict guidelines now in place regarding their collecting, processing, storage, and sharing of an individual’s personal data. All healthcare organisations must comply with the newly implemented GDPR principles regarding healthcare data, including public authorities like the NHS trust and private healthcare providers.\nThe GDPR princes are therefore vital for all healthcare businesses operating throughout Europe. Let’s look at why they are so important:\nLawful Basis of Processing Healthcare Data\nThe GDPR principles apply to personal data, which is any type of information that can be used to identify a person. For example, name, phone number, IP address, and home address are all considered personal data under GDPR, which are all used and stored by healthcare businesses.\nHowever, personal data isn’t the only form of data that is protected under GDPR. Healthcare data is considered ‘special category’ data under this new legislation, meaning there are even stricter guidelines in place regarding the processing of healthcare data.\nAll healthcare data must be processed lawfully, fairly, and with complete transparency under GDPR principles. Patients must give explicit consent for the use of their data, while healthcare businesses must show that patients understood and accepted the uses of their data and can easily withdraw consent.\nThis means various healthcare business must adjust their consent clauses to ensure they are compliant with the new principles under GDPR.\nConsent Isn’t Always Required\nWhile the GDPR principles require explicit consent for the lawful basis of healthcare data processing, there are other forms of lawful bases that justify the use of personal data. Healtcare businesses must be able to demonstrate at least one of the six lawful basis for processing of personal healthcare data.\nVital interest is a justification where the processing is necessary to protect the individual’s life, so is one that is often applied in healthcare situations. For example, if a patient is unable to consent due to their health condition but data processing is required for life-saving treatments.\nSimilarly, legitimate interest is another justification that applies to healthcare data where the use of data is done in the legitimate interests of the individual. Charities and private healthcare organisations may use this justification, with researching healthcare data used for legitimate interests.\nPublic task is a justification that is likely to be vital for healthcare businesses processing personal data. For instance, healthcare research organisations are likely to use this justification.\nThis is because their processing of healthcare data is not used for any financial gain, but instead for the benefit the general public, such as helping to plan and improve healthcare services, diagnosis process, effectiveness of healthcare policy etc.\nEven when using these justifications for medical research, strict safeguards must be in place by healthcare businesses using this sensitive data. This includes minimising the use of personal data when possible, such as using anonymous data rather than personal data when referring to an individual.\nRecords of All Data Processing is Required and Data Protection Officers (DPO) May be Needed\nNot only must healthcare businesses have lawful basis for the use of personal healthcare data, they must keep detailed records of processed data. This includes where the sensitive data was is currently stored, how it is processed, and who it is shared with.\nGiven the massive amounts of sensitive data processed and stored by healthcare businesses, according to Findbettingsites, it’s likely that a data protection officer (DPO) is needed to help manage data records.\nIn the case of public administrators – such as the NHS – this is a mandatory obligation, so most hospitals are now using data protection officers to ensure data processing and storage records are compliant with GDPR.\nPatients Have More Control Over Their Data\nThe GDPR is the most significant data protection law currently in place, providing the individual with much more control over the processing and storage of their data. As a result, everyone has more rights to access their personal healthcare data and object to its use for any form of direct marketing purposes.\nFurthermore, any healthcare business that receives a request to access personal data must show what data has been collected and how it is handled.\nShould the individual request their data be deleted, then this must be done with proof that the data is permanently erased, with GDPR principles providing individuals with the right to be forgotten.\nThat said, there are some exceptions to requests of data erasure. For instance, if the purpose of processing the data is for ongoing medical care then the request may be denied. Therefore, data can only be entirely removed from records if there are no legitimate reasons for its continued use.\nFailure to Meet GDPR Principles Can Result in Massive Fines\nGDPR is all about providing every person’s data with greater protection. Given the recent data leaks with the NHS and many other businesses, GDPR principles aim to rebuild trust between the public and healthcare organisations handling personal data.\nAny healthcare business that fails to comply with any GDPR principles face significant fines. For example, a maximum fine of €20,000,000 or 4% of global turnover is now applicable to businesses that fail to meet GDPR compliance.\nThis is a significant increase in previous fines for data breaches, which was set to just €500,000.\nThis is obviously a massive fine that has serious ramifications on any business, giving healthcare organisations plenty of reason to improve their data protection processes and methods.\nNot all breaches immediately result in a fine, while the amount is a maximum fine so not all companies with receive this, but it certainly gives healthcare businesses all the incentive they need to remain fully complaint with GDPR principles.\nAny business involved in a data breach must also inform the ICO of the incident within 72 hours, ensuring fast action is always taken should the worst happen. The ICO also looks at breaches on a case-by-case basis, considering the nature, severity, and scale of the breach and the type of data before imposing action.", "pred_label": "__label__POS", "pred_score_pos": 0.8163604736328125}
{"content": "Optimism related to the airfreight market was evident in the latest Index. For the current situation, the index noted a 1.6-point jump from August to 45.3. While still below the 50-level, this is the highest point for the current airfreight market since the Stifel Logistics Confidence Index began in early 2012. By trade lane, the Europe-US lane recorded an exceptionally strong increase at 4.9 points, while the US-Europe lane recorded a more marginal increase of 0.8 points. While both lanes still indicate contractions compared to expectations at 47.9 and 45.7, they too, are at the highest levels since the Index first began. The improving economies for the US and Europe are perhaps among the reasons for this growth.\nThe Logistics Confidence index continues to indicate increasing optimism among European freight forwarders in regards to the next six months for the airfreight market. In particular, on the Asia-Europe lane which noted the largest gain from August, increasing 4.6 points from August to 60.4. This may indicate the potential increase in spending as the holiday season approaches. The overall sea freight index noted a 0.4 decline to 54.1. The decline was noted in both the present situation which declined 0.4 points to 48.4 and six months expectations which declined 0.5 points to 59.7. The decline may be due to rate implementations and announcements for additional rate adjustments effective September 1. It was particularly interesting to note that the US trade lanes were negatively affected for both present and future expectations; meanwhile the Asian trade lanes were mixed. Despite the downturn in the sea freight index, in this month's unique question, survey participants were asked if they believe there will be a peak season in 2013. The mixed results indicated uncertainty among participants as 42.4 percent indicated there would be a peak season, while 36.7 percent indicated there wouldn't and 20.9 percent were unsure. However, a general consensus among the survey participants was the feeling there would be no peak season for the European market as the region was still recovering. Other participants expect a peak season to occur in late October or early November. The Logistics Confidence Index indicates there should be a positive change in the next six months, climbing 0.5 points to 59.1 for September. Confidence is on the rise as freight forwarders expect improving market conditions and increases in volumes. The Stifel Logistics Confidence Index is generated from an extensive survey of global logistics professionals, asked to provide their views on current levels of volumes in the industry and their expectations for six months' time. An index value of 50 indicates no change in the volumes currently being experienced for the time of year; above 50 indicates higher volumes, while below 50 indicates lower volumes. Source: Transport Intelligence\nRELATED CONTENT\nRELATED VIDEOS\nTimely, incisive articles delivered directly to your inbox.", "pred_label": "__label__POS", "pred_score_pos": 0.9778905510902405}
{"content": "From a recent article by Henry Kissinger in\nThe Atlantic. Users of the internet emphasize retrieving and manipulating information over contextualizing or conceptualizing its meaning. …Information threatens to overwhelm wisdom. Inundated via social media with the opinions of multitudes, users are diverted from introspection; in truth, many technophiles use the internet to avoid the solitude they dread. All of these pressures weaken the fortitude required to develop and sustain convictions that can be implemented only by traveling a lonely road, which is the essence of creativity.", "pred_label": "__label__POS", "pred_score_pos": 0.9894904494285583}
{"content": "Abstract\nThe Roadmap for America's Future Act of 2010 is a detailed reform package that overhauls Social Security, Medicare, Medicaid, and the U.S. federal tax system. In a January 27, 2010, report, the Congressional Budget Office (CBO) analyzed the spending provisions of the plan. This paper presents the Tax Policy Center's estimates of the revenue and distributional impact of the Roadmap's tax provisions.\nCenters\nCenters:\nTo reuse content from Urban Institute, visit copyright.com, search for the publications, choose from a list of licenses, and complete the transaction.", "pred_label": "__label__POS", "pred_score_pos": 0.9985681176185608}
{"content": "Abstract\nThis paper outlines the provisions of the Democratic alternative to the President's stimulus plan. Their plan would provide a one-time rebate to working people similar to the program implemented in 2001, but available without regard to tax status. The tax provisions proposed by the Democrats would cost $90 billion in 2003 and $59 billion over ten years.\nTo reuse content from Urban Institute, visit copyright.com, search for the publications, choose from a list of licenses, and complete the transaction.", "pred_label": "__label__POS", "pred_score_pos": 0.8502068519592285}
{"content": "As children, we looked to our parents to meet nearly every need. Our parents instinctively provided love, support and guidance as they raised us to become independent adults. Now, as our parents age, there may come a time when we adult children evolve into the role of a “parent” to our parents. Parenting a parent presents unique challenges, so here are a few tips to help navigate this new role:\n1. Understand your parent’s specific needs\nDo they need help with medication management? Do they need guidance with their budget? Do they require hands-on assistance with activities of daily living such as brushing their teeth, taking a bath, or making dinner? Understanding their specific needs helps adult children to act in a supportive role, while still maintaining their dignity.\n2. Customize a Plan to Help Your Parent\nEach senior has a unique situation. Your parent may only need help managing their finances, and this is all of the guidance and support that they need. As much as possible, allow them to maintain a sense of control, while still getting necessary help.\n3. Acknowledge Their Need for Independence\nParenting a parent is an ongoing challenge and the key to a successful transition from adult child to senior caregiver is to preserve and protect your parent’s dignity. Try to refrain from using a condescending tone or treating them in a childlike manner. Instead, ask for their input in decisions, while still providing them guidance as needed. This will make the role reversal easier for the both of you.\n4. Practice Gentle Assertiveness\nRemember, this is your parent and now you are assuming the role of their parent. When addressing difficult topics, be respectful but assertive. It will take time for both of you to adjust to the shift in the dynamic. This is most important when dealing with safety concerns, such as driving or living alone.\n5. Focus on the positive\nIt is easy to get lost in the duties of your new role, but always remember to enjoy the time you have with your loved one.Over time, relationships and roles evolve. Be patient with yourself and your parent as you embrace this new dynamic. Never forget all of the valuable life lessons that your parents shared with you, therefore make it your goal to parent them in a similar way.", "pred_label": "__label__POS", "pred_score_pos": 0.9946111440658569}
{"content": "Description\nWinter storms producing wet, heavy snow and ice can significantly damage trees and shrubs. Healthy, well-managed trees and shrubs are resilient, but some careful action by the homeowner can minimize the potential for damage.\nManagement/Methods: Tools Long-handled broom or garden tool Lopping shears Pruning saw Method Starting with branches no higher than you can reach, use gentle, upward strokes to remove the snow from the branch(es) with the broom or your hand. Alternately, use the handle of the broom or garden tool to gently lift the branch from underneath to dislodge the snow. Do not shake the branch; tree and shrub branches are brittle in winter and can easily break or split. Do not attempt to remove ice – allow it to melt off. Do not use a ladder to extend your reach. If branches are broken or damaged already, prune only those branches required to remove immediate safety hazards; to minimize further winter damage, complete any repair pruning in late winter just before the growing season. Consult an arborist or tree service to prune branches higher than you can reach and fallen limbs on cars, houses, and electrical wires.", "pred_label": "__label__POS", "pred_score_pos": 0.8333977460861206}
{"content": "NCASE Resource Library Featured Resources\nThis publication features some of the best resources, including webinars, briefs, and toolkits, available in the online NCASE Resource Library, developed for both practitioners and system builders.\nThese selected resources, curated by NCASE, offer ideas and information for OST system leaders to support recovery from COVID-19.\nThe NCASE Out-of-School Time Professional Development System-Building Toolkit was designed to assist states as they build professional development systems inclusive of school-age providers.\nSearch for Resources ? Search Results Filter By Reset Selections Expand All Filters Topics Resource type Publisher Search Results Filter By\nIn the context of COVID-19, this webinar explores Native American and Alaska Native (AIAN) traditions, philosophies, and strengths. It demonstrates how, in AIAN communities, contemporary challenges are viewed in a larger historic and spiritual framework that gives people hope and helps them adapt, cope, and heal. This wisdom guides AIAN Head Start and Early Head Start programs.\nThis website provides basic information about substance misuse among families with children.\nThis toolkit is designed to support states and territories in designing a policy approach to promote social emotional development and reduce the likelihood of expulsion and suspension.\nThis website offers resources on a range topics related to healthy youth development, with the goal of helping users create, maintain, and strengthen effective youth programs.\nThis self-assessment tool is designed to help providers evaluate how to be more responsive in serving children and families experiencing homelessness. It includes indicators and related resources on how to identify and support families, removing barriers, responding to family needs, strategic collaboration, and collecting data. This resource supports resilience.\nThis document provides links to teaching resources, training models, publications, and other resources to assist child care providers and families as they help children recover from exposure to a natural disaster or other traumatic event. It includes links to relevant federal agencies, national organizations, and additional publications.\nThis webinar defines child care deserts and explores how two organizations have developed data-driven analyses to identify where there is persistent undersupply. The data demonstrate that lack of child care disproportionately impacts rural communities, low-income communities, and Latino and American Indian and Alaska Native families.", "pred_label": "__label__POS", "pred_score_pos": 0.9351266622543335}
{"content": "Emphasize the importance of progress, not perfection, in your classroom — especially when teaching perfectionists.\nWhether cultivated through high parent expectations, a self-esteem problem, or intrinsic motivation, some students struggle with perfectionism, which can create challenges for teachers. These students often cannot accept what they perceive as failure. Though the crushing blow of receiving a D on an exam might register as failure for many students, when teaching perfectionists, educators might be tasked with calming pupils who become upset after having one assignment or project graded as a B.\nOther perfectionists don’t exhibit overachiever qualities, but prefer to consistently work at an average academic level, due to a fear of trying something new and failing, or discovering that they’re not as smart as they thought they were. Reaching these pupils can be difficult, but with the correct approach, you can help create a healthy student self-image and begin properly teaching perfectionists.\n1. Failure is Fine\nSure, a student who consistently receives failing grades is exhibiting signs of a problem, but teaching perfectionists who don’t see the value in occasional failure can also be detrimental to the learning process. As a teacher, emphasize the importance of making mistakes and learning from failure. By examining their and others’ mistakes and learning where errors lie, students see the complete process of correctly working out a problem — and avoiding the same failure in the future.\n2. Cultivate a Growth Mindset\nWhen teaching perfectionists who exhibit a fixed mindset, teachers face the challenge of overcoming a student’s opinion of themselves as having a limited, or fixed, ability to excel in certain subjects, which can cause anxiety. By cultivating a growth mindset within the classroom, teaching perfectionists will become easier, as these students will begin to embrace failure as a stepping stone toward mastery through hard work. Start by joining Amazon’s\nWith Math I Can initiative to help students develop a growth mindset. 3. Teach Helpful Habits\nAverage students who are afraid of their own potential are typically those pupils who can excel, yet don’t dedicate additional effort due to their fear of failing after they succeed. Encourage these students to take ownership of their success, but emphasize that you will help them reach their full potential. At their purest form, great study methods can cross subjects, for example, excellent vocabulary memorization tools can also be applied to mastering math, or chemistry, concepts. When these students succeed, emphasize their excellence. When they fail, do not exhibit disappointment, but point out their dedication to the process and work with them to master the concepts on which they are weak.\n4. Use Peer Assessment\nCreate a trusting environment for all students to succeed by emphasizing mutual respect and implementing peer assessment. Through creating an environment in which students help each other through offering positive feedback and critique, teachers can increase trust within the classroom. This approach is useful when teaching perfectionists, as the fear of failure will decrease when they begin to trust their fellow students and feel safe inside a classroom free of judgement.\n5. Make it Personal\nNothing helps teachers seem relatable more than sharing with students a personal childhood account of how they faced similar issues. Think back to your own school days and share a story of the fear you felt when trying to accomplish a goal. While telling the story, be certain to add the questions that will allow students to relate, such as “How will I top this achievement?,” “What if another student performs better?,” and “Will my parents and teacher be disappointed in me if I fail?”\nMany habits are difficult to break, therefore be patient when teaching perfectionists. Perfectionists often feel the need to have control of every situation. Convincing these students to accept help isn’t easy, but building a support system for them will facilitate the process of teaching perfectionists and help them achieve their potential.", "pred_label": "__label__POS", "pred_score_pos": 0.5605560541152954}
{"content": "Those who have been following my recent posts know that I've started working on a new manifestation for greater wealth.\nPartly to see what will happen when I approach it as if I \"really needed\" it.\nIn other words, in the imagination portion of the process (\nrelax, imagine, trust), I'm expressing an intense feeling of gratitude and joy, as if the increased wealth really made a dramatic difference in my life.\nWhen you're comfortable and happy with your life, this isn't as easy as you might imagine.\nIt's been an interesting experiment, to say the least.\nOne of the insights I'd like to share with you relates to the fact that for the first day or two, I really didn't have a specific idea of what that level of wealth would look like.\nHave you ever felt that something was missing, but you just couldn't put your finger on exactly what would complete your life's picture?\nIf so, then this might give you a way to move forward, even without a specific goal in mind.\nWhen you don't have a specific thing you want to manifest, the thing to focus on is the FEELING you want to experience.\nIn the case of wealth, or at least the level of wealth I'm working towards now, the feeling may best be described as an overwhelming sense of gratitude and joy.\nNow, I want to be very clear about the level of feeling I'm talking about here.\nI'm not talking about a feeling of \"Oh, isn't that nice\", but more like \"Oh my GOD! This is the most amazing thing EVER!!\"\nFrom a neurological standpoint, the stronger the feeling, the more deeply the thought-image will be engraved into your memory, and the stronger the belief created from it.\nAnd it's the belief that makes things happen.\nThe strong feeling is used to help create the belief, not to \"send out a pulse of energy\" as many people believe.\nThis is as good a place as any to bring up a related point.\nWhen I'm doing this, I'm not analyzing the process.\nI'm not visualizing the energy being created, going out into the world, and affecting things outside myself.\nIf I were to analyze the process, or wonder how it might work, I'd be diffusing my efforts.\nAnd the way I'm approaching this project, if I were to diffuse my efforts, I wouldn't be doing the absolute best I could.\nAnd if I REALLY NEEDED the manifestation, that wouldn't be good enough.\nWhen you NEED a result, you NEED to put yourself 100% into the process.\nYou can't hold anything back.\nNot one iota of energy.\nConsider it as all or nothing.\nEven when the only thing you know you want is a feeling of joy and gratitude.\nTomorrow, I'm going to explain one of the most important aspects of manifestation.\nIn the meantime, if you want to get a head start on developing the skills you need to manifest at the highest level, grab a copy of my\nSymbolic Solutions 2.0 package now.", "pred_label": "__label__POS", "pred_score_pos": 0.6821138858795166}
{"content": "The impact of COVID-19 on domestic and international industries is severe, across all sectors. There are several legal issues that a company must face during the COVID-19 outbreak. One such legal issue is the occurrence of a force majeure event. A force majeure claim may protect a party from liability for its failure to perform its contractual obligation(s).\nManual for Procurement of Goods 2017 – Office Memorandum dated 19 February 2020\nThe Ministry of Finance (Department of Expenditure), vide its office memorandum (No. F.18/4/2020-PPD dated 19 February 2020), clarified that disruption of supply chains due to the spread of Coronavirus in China or any other country will be covered under the Force Majeure Clause (as defined in the Manual for Procurement of Goods, 2017).\nPara 9.7.7 of the Manual for Procurement of Goods 2017 states the following with regard to the ‘Force Majeure Clause’:\nForce majeure is an extraordinary event/circumstance that is beyond human control and has been described as an act of God, natural disasters, war, strikes, riots, crimes (but it does not include negligence or wrong-doing, predictable/seasonal rain or any other event specifically excluded in the clause). Such a clause in the contract frees both parties from liability when prevented by such event from fulfilling their contractual obligations. A Force majeure clause is not an excuse for the parties’ non-performance entirely, and only suspends it for the duration of the force majeure event. If a force majeure clause is triggered, a notice of force majeure should be given to the other party as soon as such event occurs. Protection cannot be claimed ex-post facto. Where a force majeure event affects only the purchase organization, the purchase organization is to communicate with the supplier along similar lines as above for further necessary action. If the performance of the contract is prevented or delayed as a whole or in part for a period exceeding 90 days, either party may terminate the contract without any financial repercussion on either side.\nThis Office Memorandum essentially suggests that COVID-19 could be construed as a natural calamity which would excuse non-performance of contractual obligations, although certain prescribed procedural safeguards must be followed by the party seeking to invoke the clause.\nHowever, it must be noted that the office memorandum does, to a large extent, over-simplify the grounds on which force majeure protection can be claimed by a party. Further, this office memorandum does not automatically assure the success of a party invoking such a claim, even on the grounds of COVID-19.\nTo appreciate the nuances relating to Force Majeure, it is important to understand the jurisprudence of the concept under the Indian Contract Act, 1872.\nWhat is Force Majeure? Force majeure is a French expression which translates, literally, to “superior force”.\nIn the context of law and business, the Merriam Webster dictionary states that force majeure usually refers to\n“those uncontrollable events (such as war, labor stoppages, or extreme weather) that are not the fault of any party and that make it difficult or impossible to carry out normal business. A company may insert a force majeure clause into a contract to absolve itself from liability in the event it cannot fulfill the terms of a contract (or if attempting to do so will result in loss or damage of goods) for reasons beyond its control”[1].\nBlack’s Law Dictionary defines Force Majeure as follows,\n“In the law of insurance, superior or irresistible force. Such clause is common in construction contracts to protect the parties in the event a part of the contract cannot be performed due to causes which are outside the control of the parties and could not be avoided by exercise of due care… Typically, such clauses specifically indicate problems beyond the reasonable control of the lessee that will excuse performance.”[2]\nIn India, it is often referred to as an “act of God”. However, the term “force majeure” has not been defined in any Indian statute. Various courts have, over time, held that the term force majeure covers not merely acts of God, but may include acts of humans as well.\nThe concept of Force Majeure is straightforward – in every contract in which parties undertake to fulfill obligations in the future (called an “executory contract”), the failure to perform such obligations will give the aggrieved party the right to claim damages from the defaulting party. However, if such failure to perform is due to events beyond the defaulting party’s control, then the defaulting party must not be held liable. The force majeure clause, therefore, allows one or more parties to a contract to avoid, suspend or postpone its performance, in whole or in part, on account of events beyond their control. The devil, as always, lies in the details.\nImpossibility v. Frustration\nThe term “Force Majeure” is based on the concept of the Doctrine of Frustration under the Indian Contract Act, 1872 (particularly Sections 32 and 56, discussed in greater detail below); and has been developed through decades of judicial interpretation. The law uses the term “impossible” while discussing the frustration of a contract, i.e., a contract which becomes impossible has been frustrated. In this context, “impossibility” refers to an unexpected subsequent event or change of circumstance which fundamentally strikes at the root of the contract. This is construed in a practical, and not a literal, sense.\nIn a large body of cases, including Alopi Parshad and Sons Ltd vs Union of India, AIR 1960 SC 588 and the landmark Energy Watchdog and Ors. Vs. Central Electricity Regulatory Commission and Ors (2017) – 2017 3 AWC 2692 SC, the Supreme Court of India has categorically stated that mere commercial onerousness, hardship, material loss, or inconvenience cannot constitute frustration of a contract.\nFurthermore, if it remains possible to fulfill the contract through alternate means, then a mere intervening difficulty will not constitute frustration. It is only in the absence of such alternate means that the contract may be considered frustrated.\nForce Majeure under Indian Law\nThe two key sections of the Indian Contract Act, 1872 which are relevant for this discussion are:\nSection 32 (Enforcement of contracts contingent on an event happening), which states that “Contingent contracts to do or not to do anything if an uncertain future event happens, cannot be enforced by law unless and until that event has happened…”\nThe impossibility of a performing a contract under Section 32 may arise not only due to a force majeure event but also due to the non-occurrence of any underlying condition in the contract. For instance, illustration (b) of Section 32 under the Contract Act states:\n“A makes a contract with B to sell a horse to B at a specified price, if C, to whom the horse has been offered, refuses to buy him. The contract cannot be enforced by law unless and until C refuses to buy the horse”.\nIn\nEnergy Watchdog and Ors. Vs. Central Electricity Regulatory Commission and Ors (2017) – 2017 3 AWC 2692 SC (paragraph 34), the Supreme Court observed, “where the Court finds that the contract itself either impliedly or expressly contains a term, according to which performance would stand discharged under certain circumstances, the dissolution of the contract would take place under the terms of the contract itself and such cases would be dealt with under Section 32 of the Act. If, however, frustration is to take place de hors the contract, it will be governed by Section 56.” Section 56 (Agreement to do impossible act) states that “a contract to do an act which, after the contract is made, becomes impossible, or, by reason of some event which the promisor could not prevent, unlawful, becomes void when the act becomes impossible or unlawful.”\nIt must be noted that for a contract to be frustrated under Section 56,\nit is the performance of contractual obligations that must become unlawful/impossible, not the ability to enjoy benefits under the contract.\nSection 56 will govern frustration of contract where the such frustration is not contemplated in the contract itself. In the absence of a force majeure clause in the contract, it must be shown by the party seeking protection that it has become impossible for such party to perform its contractual obligations, and that the intent of the parties in entering into the agreement has been so entirely frustrated, that the contract’s fundamentals have irreversibly changed. In such a case, the parties can seek to invoke section 56 of the Indian Contracts Act.\nIf Section 56 applies to a contract, then parties will be discharged from their obligation to perform a part of the contract, or the entirety of the contract.\nThe Supreme Court in Boothalinga Agencies v. V.T.C. Poriaswami Nadar (1968) [AIR 1969 SC 110] observed that,\n“The doctrine of frustration of contract is really an aspect or part of the law of discharge of contract by reason of supervening impossibility or illegality of the act agreed to be done and hence comes within the purview of Section 56 of the Indian Contract Act. It should be noticed that Section 56 lays down a rule of positive law and does not leave the matter to be determined according to the intention of the parties.” The Court continued and stated that while the English Law treated frustration of contracts as a question of construction; depending upon the true intention of the parties, the Indian Contract Act lays it down a positive rule of law.\nThe Supreme Court in\nEnergy Watchdog and Ors. Vs. Central Electricity Regulatory Commission and Ors (2017) – 2017 3 AWC 2692 SC lent further insight into interpreting a Force Majeure situation: Events beyond the reasonable control of one party should not render that party liable under a contract for performance, if that event prevents the party’s performance; The language of the agreement relating to duty to mitigate, best efforts, prudent man obligations to nevertheless perform etc., will all be taken into consideration in understanding the parties’ intent; Force majeure events must be unforeseeable by both parties; The requirement to put the other party on notice must be met with if the contract provides for notice requirements; and Burden of proof rests with the party relying on the defense of force majeure for its inability to perform the obligation. Express Exclusions\nIt is crucial to note that where events or circumstances are expressly excluded from the definition of force majeure under a contract, there can be no frustration on the occurrence of such an event (Satyabrata Ghose vs. Mugneeram Bangur et.al., AIR 1954 SC 44).\nTherefore, the definition of “Force Majeure” under a contract becomes critical.\nConsequence of Force Majeure\nMost commercial agreements contain a clause on force majeure, which provides protection to the parties to the agreement, against claims and liabilities arising out of non-performance or breach of the contract due to certain specified force majeure events.\nIf the force majeure clause in an agreement contains specific consequences, then it is those consequences that will apply, irrespective of the provisions of Section 32/Section 56. If no alternate consequence is provided for under the agreement, then the provisions of Section 32/56 will apply. Therefore, it becomes pertinent to carefully consider the language of the force majeure clause in the contract in question.\nTemporary Suspension of Contract\nThe texts of Section 32 and Section 56 do not explicitly contemplate a situation where the contract remains valid although a party’s obligations are suspended or postponed due to force majeure.\nAlthough Section 56, illustration (e), does discuss a situation of partial discharge of a contract, it may not be wise to place too much reliance on it, as the Supreme Court in Satyabrata Ghose vs. Mugneeram Bangur et.al., AIR 1954 SC 44 has noted that the illustrations to Section 56 are flawed in their wordings and, “cannot derogate from the general words used in the enactment”.\nAdditionally, Section 56 illustration (e) only envisages the partial discharge of a severable contract and does not envisage a temporary suspension of obligations under a contract.\nThere are no precedents for this concept and the manner in which various courts will interpret this aspect remains to be seen.\nHowever, nothing prevents parties from contractually agreeing that the occurrence of certain events shall only cause temporary/partial suspension of obligations under a contract.\nBurden of Proof\nThe onus of proving the existence of a force majeure event lies on the party claiming benefit under it. This includes the burden of proving that the non-performance was caused due to force majeure, that steps were taken to mitigate the loss, that the procedural requirements (if any) under the contract were observed etc.\nOnce the existence of a force majeure is proved, the burden of proving the existence of alternate means of fulfilling the contract will fall on the counterparty/counterparties.\nThe Court will, of course, carry out its own examinations to arrive at its conclusion.\nForce Majeure in the time of COVID\nCOVID-19 may, at most, constitute a temporary impossibility in the fulfillment of a contract.\nIf time is of the essence in a contract, COVID-19 may result in the contract being frustrated. However, this is purely a question of fact and depends on the specific circumstances of each case. In all other contracts, unless COVID-19 renders a contract impossible, the obligations continue to persist.\nWhether or not a Force Majeure clause, which permits temporary suspension of obligations, covers the COVID pandemic is a question of interpretation. The terms “pandemic” or “epidemic” may be expressly defined as forming part of Force Majeure, or it may be possible to argue that such terms are included by implication. However, if the clause expressly excludes such events, then COVID-19 will not constitute a force majeure event.\nTherefore, the applicability of Force Majeure protection to COVID is a question of fact and interpretation and has no direct precedent in Indian jurisprudence.", "pred_label": "__label__POS", "pred_score_pos": 0.6236028075218201}
{"content": "The Rising Popularity of Cloud Computing and Digital Payments\nThe future of payments lies in the cloud. Prior to the pandemic, the widespread adoption of cloud computing was already prevalent, with industries like healthcare, marketing, retail, and finance all embracing the technology to supercharge their operations. In healthcare, the cloud is used for securing and storing electronic health records, while the marketing sector uses it to automate routine tasks and track trends. Retail businesses utilise cloud technology to market to their customers more effectively, and the finance industry leverage it to make expense management and digital payments much more efficient.\nWhile the situation is not ideal, the outbreak has become the turning point for the payments industry. Enterprises that had invested heavily in cloud solutions have been able to continue with less interference compared to those who didn’t. Since March, cloud-based services for remote workers were responsible for keeping the world working, due to many businesses being forced to shut down and transition to a work-from-home setup. Those previously opposed to the concept are also starting to realise its benefits, and if the prediction by Global Data proves to be correct, the cloud services market will blow up to a whopping $661 billion (£528 billion) by 2024. That clocks into a 19% annual growth rate between 2019 and 2024.\nIn the coming months and years, the biggest tech companies, including Amazon, Microsoft, Google, Alibaba, and IBM, are likely to position themselves as the superior cloud-based collaboration and application providers. Google is already at the forefront of this movement, with Google Cloud announcing that it has signed a Memorandum of Understanding (MoU) with the UK Crown Commercial Service (CCS) in an effort to make it easier and more affordable for public sector agencies across the UK to take advantage of Google Cloud’s full range of services. This project will aid them in providing a seamless digital transformation for the British public.\nSimon Tse, Chief Executive of CCS, highlights how the MoU will also lead to large-scale business benefits for customers and emphasises the CCS’ role in helping the public sector serve the nation in more novel and innovative ways. Organisations will get the chance to leverage a range of technologies available in the cloud, including, but not limited to infrastructure, analytics, artificial intelligence, application modernisation and development, workflow management, and collaboration solutions.\nThis initiative is likely to push the adoption of cloud computing even further forward, leading to an even more widespread adoption of digital payments. A report by The Business Research Company noted that the decline of cash payments in-store was due to the advice of government bodies and health institutions, resulting in the rise of contactless payment methods. Businesses struggling to stay afloat will definitely benefit from using a cloud-based payment system, given how it’s more convenient and safer for customers due to reduced physical contact and its enhanced data security. Indeed, popular payment provider FIS Global details how cloud-based solutions can integrate seamlessly with a variety of payment channels and platforms, enabling large enterprises to access the same network from around the world. This helps ensure that retail transactions stay securely encrypted due to real-time updates being carried out across all systems. Sensitive data is also tokenised, a process in which a unique identifier is assigned the secure information, allowing businesses to safely conduct payment transactions. This applies to almost all digital payments available, whether it’s recurring bills, subscriptions, or one-time fees.\nThere’s no doubt that organisations and businesses will benefit from transitioning to the cloud should they decide to do so. However, it should not be done in haste. CIO underscores how transitioning from on-premises infrastructure to multi-cloud or hybrid cloud is no easy feat, and one must consider making a cloud-first commitment. This means taking a deep dive into cloud computing and gaining an in-depth understanding of its economics, as well as planning for continuous compliance. Any mistakes will be very costly to rectify.\nBut what is clear is it that from here on out cloud computing is no longer a novel phenomenon. It’s here to stay, and, in fact, it’s only just getting started.", "pred_label": "__label__POS", "pred_score_pos": 0.5607335567474365}
{"content": "Data collection, analysis and interpretation plays a crucial role in a research work as it provides a deeper understanding of the various concepts and frameworks used. Data analysis, when conducted in an accurate manner, can make your research. However, it should be noted that, not just performing the data analysis in a right manner gives […]", "pred_label": "__label__POS", "pred_score_pos": 0.9999065399169922}
{"content": "Greenwashing is a marketing ploy, akin to whitewashing, where fundamentally toxic and unsustainable businesses exaggerate the value of their environmentally-sustainable and -responsible practices. WalMart, Home Depot and a number of food manufacturers have been accused of greenwashing. Washing green is, well, keeping your surroundings, clothing and person as clean as possible by using non-toxic materials, often derived from non-petroleum and non-animal sources. Yesterday, the Washington Post ran an article comparing leading green cleaning lines, though I wish more samples from the specific categories were compared.", "pred_label": "__label__POS", "pred_score_pos": 0.9817151427268982}
{"content": "Electrically Conducting Polymers\nThis year marks the 40th anniversary of Shirakawa, MacDiarmid, and Heeger’s first ground-breaking publication on electrically conducting polymers. Their original studies were based on polyacetylene, but work quickly progressed to other classes of polymers, including poly phenylenes, poly (phenylenevinylenes), polyanilines, and the poly heterocycles. While “electrically conducting polymers” is, of course, an apt description for these materials, that description fails to capture the most important feature of these polymers: changes in oxidation state result in changes in many properties, including not just conductivity but also color, volume, reactivity, permeability, and solubility. For this reason, describing these materials as “electroactive polymers” might be more appropriate.", "pred_label": "__label__POS", "pred_score_pos": 0.7871106266975403}
{"content": "The Royal Society’s Face mask report says if correctly used face masks, including homemade cloth masks, can contribute to reducing viral transmission. Masks can offer an important tool for contributing to the management of community transmission of Covid19 within the general population. The report says evidence supporting their potential effectiveness comes from analysis of (1) the incidence of asymptomatic and pre-symptomatic transmission; (2) the role of respiratory droplets in transmission, which can travel as far as 1-2 meters; and (3) studies of the use of homemade and surgical masks to reduce droplet spread.\nA comprehensive study shows wearing masks significantly reduces the number of infections, far more than other measures such as social distancing. It shows that airborne transmission is highly virulent and dominates the spread of COVID-19. It reveals that the difference with and without masks represents the determinant in shaping the trends of the pandemic.\nLink to article: https://www.pnas.org/content/early/2020/06/10/2009637117\nComparison of face mask use recommendations by different health authorities. Despite the consistency in the recommendation that symptomatic individuals and those in health-care settings should use face masks, differences in recommendations were observed for the general public and community settings. Evidence that face masks can provide effective protection against respiratory infections in the community is scarce. However, face masks are widely used by medical workers as part of droplet precautions when caring for patients with respiratory infections. The study suggests vulnerable individuals avoid crowded areas and use surgical face masks rationally when exposed to high-risk areas.", "pred_label": "__label__POS", "pred_score_pos": 0.5852981209754944}
{"content": "Successful outcomes benefit defendants, prosecutors, enforcement agencies, magistrates, the court service and taxpayers.\nBackground\nThe Single Justice Service (SJS) enables magistrates’ courts to deal with low-level crimes and offences (such as speeding, fare evasion, or not having a TV licence) in a way that is quick and efficient for everyone involved – including the defendant – while still being fair and rigorous. It includes an online digital case management system for summary cases.\nAlmost 1 million summary cases in England & Wales were dealt with by the service in the 12 months before July 2019.\nBefore its introduction, engagement rates from defendants in summary cases were low, with the majority of defendants not responding to plea notices. This impacted courts and enforcement agencies because defendants who didn’t respond to notices often rejected judgments on the grounds of being unaware of the case.\nAppeals against fines for summary cases were common and costly. To reduce appeals and simplify the process, we re-designed plea notices (Single Justice Procedure Notice – SJPN) so they are more engaging and easier for defendants to understand.\nConsulting stakeholders\nWe worked with public user organisations, prosecuting agencies and legal professional representative bodies throughout the design process.\nOrganisations we consulted include:\nJustice HMCTS’ defendant’s voice engagement group several police forces including the Metropolitan Police the Driver & Vehicle Licensing Agency (DVLA) Television Licensing the Bar Council the Law Society the Chartered Institute for Legal Executives (CILEx).\nWe also worked with behavioural scientists and designers before user experience researchers tested the new notices with the public to understand the effectiveness of the notices in real-life situations.\nClarity for defendants\nWe added an introductory covering letter to which explains clearly to defendants:\nwhy they have received the notice what they need to do the consequences for not responding.\nNotices had previously stated that a response was required within 21 days of the date of issue. The re-designed notice includes a specific date for responding as well as guidance for submitting a plea online. Further detailed information in plea notices include:\nan outline of the case evidence provided by the prosecutor the specific laws that may have been contravened potential penalties. Impact\nWe’ve been testing the new notices with the DVLA, TV Licensing and the Metropolitan Police and early results have been very positive.\nResponses to notices in television licensing cases increased from 20% to 27% between January and February 2020. There was a similar increase to a pilot in the Midlands.\nThe Metropolitan Police reported a 75% increase in online pleas since the new notices were introduced. Since the implementation of redesigned notices, the average number received has increased by over 200 every week.\nWhat is next?\nWe are planning to introduce a new notice for all TV Licensing cases in November 2020, followed by the same for Transport for London.\nFurther information\nFollow this news feed: HM Government", "pred_label": "__label__POS", "pred_score_pos": 0.6861136555671692}
{"content": "The global COVID-19 pandemic caused by the virus SARS-CoV-2 has led to over 10 million confirmed cases, half a million deaths, and is challenging healthcare systems worldwide. With limited medical resources, early identification of patients with a high risk of progression to severe disease or a critical state is crucial. We present a prognostic model predicting critical state within 28 days following COVID-19 diagnosis trained on data from US electronic health records (EHR) within IBM Explorys, including demographics, comorbidities, symptoms, laboratory test results, insurance types, and hospitalization. Our entire cohort included 20152 COVID-19 cases, of which 3160 patients went into critical state or died. Random, stratified train-test splits were repeated 100 times to obtain a distribution of performance. The median and interquartile range of the areas under the receiver operating characteristic curve (ROC AUC) and the precision recall curve (PR AUC) were 0.863 [0.857, 0.866] and 0.539 [0.526, 0.550], respectively. Optimizing the decision threshold lead to a sensitivity of 0.796 [0.775, 0.821] and a specificity of 0.784 [0.769, 0.805]. Good model calibration was achieved, showing only minor tendency to over-forecast probabilities above 0.6. The validity of the model was demonstrated by the interpretability analysis confirming existing evidence on major risk factors (e.g., higher age and weight, male gender, diabetes, cardiovascular disease, and chronic kidney disease). The analysis also revealed higher risk for African Americans and “self-pay patients”. To the best of our knowledge, this is the largest dataset based on EHR used to create a prognosis model for COVID-19. In contrast to large-scale statistics computing odds ratios for individual risk factors, the present model combining a rich set of covariates can provide accurate personalized predictions enabling early treatment to prevent patients from progressing to a severe or critical state.\nCollection : COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv", "pred_label": "__label__POS", "pred_score_pos": 0.9234232902526855}
{"content": "Outpatient programs are often considered a less intense form of addiction treatment care. There are no around-the-clock supervision services involved with these programs, and there are no clinicians available when a crisis hits in the middle of the night. As a result, these are programs that are often recommended for those who have:\nBeen through inpatient care before and need a treatment touchup\nNew cases of addiction, with habits that are not firm and fixed", "pred_label": "__label__POS", "pred_score_pos": 0.8577384948730469}
{"content": "The U.S. is set to drive most of the liquids storage capacity growth in North America with its planned and announced (new-build) terminals, contributing around 85 percent of the regions’ total growth between 2019 and 2023, says GlobalData, a leading data, and analytics company.\nThe company’s report, Liquids Storage Industry Outlook in North America to 2023 – Capacity and Capital Expenditure Outlook with Details of All Operating and Planned Terminals, reveals that the U.S. is expected to have new-build liquids storage capacity of 14.5 million cubic meters (mmcm) by 2023. Planned projects account for 70 percent of the new-build capacity additions in the region, while early-stage announced projects account for the remaining total.\nVarun Ette, Oil and Gas Analyst at GlobalData, comments: “In the U.S., 30 planned and announced liquids storage terminals are expected to start operations during 2019 to 2023. Of these, Plaquemines has the highest storage capacity of 3.2 mmcm and is scheduled to start in 2020.”\nFollowing the U.S., GlobalData identifies Mexico as the second highest contributor to the liquids storage capacity growth in North America with a new-build capacity of 1.9 mmcm by 2023. The country is expected to witness the start of 14 new-build terminals by 2023. Of these, eight terminals are planned with a capacity of 1.4 mmcm and the remaining six terminals are early-stage announced projects.\nEtte concludes: “Canada is expected to begin operating three liquid storage terminals by 2023 with a total capacity of 0.6 mmcm.”\nAbout GlobalData\n4,000 of the world’s largest companies, including over 70% of FTSE 100 and 60% of Fortune 100 companies, make more timely and better business decisions thanks to GlobalData’s unique data, expert analysis, and innovative solutions, all in one platform. GlobalData’s mission is to help our clients decode the future to be more successful and innovative across a range of industries, including the healthcare, consumer, retail, technology, energy, financial and professional services sectors.\nSubscribe to OILMAN Today, our industry newsletter covering oil and gas business news, events, information and trends shaping the market, delivered to your inbox.", "pred_label": "__label__POS", "pred_score_pos": 0.5715689659118652}
{"content": "Abstract\nFish, in Bangladesh where malnutrition remains a significant development challenge, is an irreplaceable animal-source food in the diet of millions. However, existing data on the nutrient composition of fish do not reflect the large diversity available and have focused on only a few select nutrients. The purpose of this study was to fill the gaps in existing data on the nutrient profiles of common fish in Bangladesh by analysing the proximate, vitamin, mineral and fatty acid composition of 55 fish, shrimp and prawn species from inland capture, aquaculture and marine capture fisheries. When comparing species, the composition of nutrients of public health significance was diverse. Iron ranged from 0.34 to 19. mg/100. g, zinc from 0.6 to 4.7. mg/100. g, calcium from 8.6 to 1900. mg/100. g, vitamin A from 0 to 2503. μg/100. g and vitamin B12 from 0.50 to 14. μg/100. g. Several species were rich in essential fatty acids, particularly docosohexaenoic acid in capture fisheries species (86-310. mg/100. g). The potential contribution of each species to recommended nutrient intakes (RNIs) for pregnant and lactating women (PLW) and infants was calculated. Seven species for PLW and six species for infants, all from inland capture, and all typically consumed whole with head and bones, could potentially contribute ≥25% of RNIs for three or more of these nutrients, simultaneously, from a standard portion. This illustrates the diversity in nutrient content of fish species and in particular the rich nutrient composition of small indigenous species, which should guide policy and programmes to improve food and nutrition security in Bangladesh.", "pred_label": "__label__POS", "pred_score_pos": 0.8915101289749146}
{"content": "The goal of this clinical research study is to find the highest tolerable dose of the combination of ixazomib and erlotinib that can be given to patients with advanced solid tumors. The safety of these drugs will also be studied. This is an investigational study. Erlotinib is FDA approved and commercially available to treat non-small cell lung cancer, but its use in advanced solid cancer is considered investigational. Ixazomib is FDA approved. The study doctor can explain how the study drugs are designed to work. Up to 36 patients will take part in this study. All will be enrolled at MD Anderson.\nName: Ixazomib Name: Erlotinib Description: MTD defined by dose limiting toxicities (DLTs) that occur during the first cycle.\nDose limiting toxicity (DLT) defined as\nAny Grade 3 or 4 non-hematologic toxicity as defined in the NCI CTCAE.\nAny Grade 4 hematologic toxicity lasting two weeks or longer (as defined by the NCI-CTCAE), despite supportive care.\nGrade 4 nausea, vomiting or diarrhea > 5 days despite maximum anti-nausea regimens. Description: Tumor response of this combination per RECIST version 1.1. Description: Tumor response of this combination per RECIST version 1.1.\nAllocation: Non-Randomized\nSingle Group Assignment\nThere is one SNP\nerlotinib or afatinib) and tested negative for\nEGFR\nT790M mutation. --- T790M ---\nWe will allow patients with positive EGFR\nT790M mutation if they\nhave progressed on third generation anti-EGFR therapy (e.g. --- T790M ---", "pred_label": "__label__POS", "pred_score_pos": 0.8927448987960815}
{"content": "If you apply for financial aid for undergraduate college or graduate school, you may be offered loans as part of your school’s financial aid offer. A loan is money you borrow and must pay back with interest.[1] Student loans can come from the federal government, from private sources such as a bank or financial institution, or from other organizations.", "pred_label": "__label__POS", "pred_score_pos": 0.8917834758758545}
{"content": "In Dari Persian words, the letter D comes either at the beginning of the word or after a consonant, and the letter Dh always comes after a vowel. This rule is specific to singular words. In compound words, however, the first letter of the second segment cannot be Dh and only a D letter must be used. It is because the preceding vowel is not a part of the morpheme itself, but belongs to the preceding morpheme. Therefore, the second segment of compound words is subject to the same rule that applies to the singular words. According to this rule, singular words such as Badheh and Nabidh have the letter Dh, and compound words such as Padash and Sotudan have the letter D in their structure.\nPersian scholars such as Shams Qais Razi, Ibn Yamin Fariumdi, and Sharaf al-Din Ali Yazdi have described how Dari Persian distinguishes between the two Persian letters, D and Dh. As they have noted, in Dari Persian, when this letter comes after a constant and a vowel phoneme, it constitutes a D and Dh, respectively. This rule only applies to singular words, and in the case of compound words, each segment of the compound represents a singular word, so the rule in question would not be applicable. For example, the word Bidhar has the letter Dh and the word Bidadh has the letter D in their structure as the third letter. It is because Bidhar is a single word and Bidadh is a compound word. It is true that the phoneme preceding the first D in Bidadh is a vowel, but this phoneme, rather than being a part of the original morpheme, is a part of the preceding morpheme, “B”. Therefore, the third letter in the word Bidadh is not Dh. However, the last letter is Dh because Dadh morpheme is singular and the vowel preceding Dh is part of the morpheme itself.\nSome interesting results and conclusion can be obtained about the linguistics in the past by examining ancient manuscripts written until the end of the eighth century, especially through a meticulous analysis of how D and Dh letters have been recorded. The difference between D and Dh in writing can indicate the pronunciation and grammatical structure of a word. The first letter of the word is always a D, but if the second or other letters are a D, one of these two conditions would be applicable. In the first case, the preceding phoneme is a consonant, and in the second case, the preceding letter (s) is a separate morpheme incorporated in the structure of the word.\nThe analysis of evidence in manuscripts provided the following\nThe word Padash is a compound that consists of two morphemes, Pa+dash. The lack of a dot in the second letter in this word suggests that Pa is a separate morpheme. The word Badidh is a compound that consists of two morphemes, Be+didh. The lack of a dot in the second letter of this word leads us to the conclusion that Be is an independent morpheme. The word Bedhast, meaning palm, is a singular word. The existence of a dot on the second letter of this word suggests that the word in question consists of one morpheme. The ancient manuscripts differ in how they have recorded the word Sotudan. Some versions have recorded it with a D and others with a Dh. Yet, others have adopted a dual approach, using D and Dh alternatively. The scientific evidence suggests that the word is made up of two morphemes, “Sotu+Dan”. Thus, we consider manuscripts that have recorded the word with D letter as the reference. Considering how letters D and Dh are dotted in this verse of Shahnameh, we can figure out whether the word used in the Florentine version is Bidar or Bidad: ورا کندرو خواندندی به نام به کندی زذی پیش بیذار گام\nA meticulous analysis of the writing style of D and Dh letters in ancient texts reveals that appropriate writing of these two letters requires some background knowledge in Persian inflection and etymology. The scribers, who have recorded D and Dh correctly, have demonstrated the level of their awareness and linguistic knowledge at their time and place of living. Today, the correct reading of manuscripts requires knowledge of rules such as D and Dh rule. Some of the editors and correctors, oblivious to this rule, have erred in reading the old versions.\nپرداخت با کارتهای اعتباری بین المللی از طریق PayPal امکانپذیر است.\nدسترسی به متن مقالات این پایگاه در قالب ارایه خدمات کتابخانه دیجیتال و با دریافت حق عضویت صورت میگیرد و مگیران بهایی برای هر مقاله تعیین نکرده و وجهی بابت آن دریافت نمیکند. حق عضویت دریافتی صرف حمایت از نشریات عضو و نگهداری، تکمیل و توسعه مگیران میشود. پرداخت حق اشتراک و دانلود مقالات اجازه بازنشر آن در سایر رسانههای چاپی و دیجیتال را به کاربر نمیدهد.", "pred_label": "__label__POS", "pred_score_pos": 0.5983484983444214}
{"content": "Avian influenza associated with H9N2 and H5N1 subtypes of avian influenza viruses (AIVs) has raised great concerns in China. To study this problem, reverse genetics has been employed. Three reassortants, rgH9N2, rgH5N1 and rgH5N2, were prepared and compared. Their hemagglutinin (HA) and neuraminidase (NA) genes originated from Chinese AIV isolates of H9N2 or H5N1 subtype, while the rest of their genes were derived from A/WSN/33(H1N1) virus (WSN). In the H5 HA reassortants, the multibasic cleavage site was converted to a monobasic one. The results demonstrated that the reassortants did not produce CPE on MDCK cells in the absence of trypsin, showed egg-adaptation phenotype and stability of HA and NA during consecutive egg passages, and were not lethal to chickens and mice. However, the rgH5N1 reassortant exhibited a residual virulence in terms of lethality to chick embryos and pathogenesis in chickens. It can be concluded that (i) the genetic modification of H5 HA attenuated the H5 reassortants, (ii) the presence of internal WSN proteins contributed to the attenuated properties of the reassortants independently on H5 HA, and (iii) also the overall genome composition contributed to virulence differences. This report provides further contribution of reverse genetics to the knowledge of virulence of influenza viruses.", "pred_label": "__label__POS", "pred_score_pos": 0.8913165926933289}
{"content": "Austin attorney order of nondisclosure. Generally defined, an order of nondisclosure is a court order that expressly prohibits police departments and courts from being able to disclose certain criminal records. This means that anyone who may currently have a criminal record will likely be able to take advantage of this type of an order.\nAdditionally, the order also legally prevents an individual from disclosing any and all information regarding their criminal history on any job applications.\nIt’s important to note that this type of order applies only to specific criminal offenses rather than all offenses on an individual’s record; however, multiple orders may be obtained for multiple offenses.\nOffenders are able to file a petition for this order if the following six conditions are met:\n*Placed on a deferred adjudication community supervision for the specific offense that was committed. This is an order should should be attached to your petition.\n*The deferred adjudication must be successfully completed.\n*The offense in question must be one that will entitle you to obtain this order. This includes offenses that require you to register as a sex offender, anything involving family violence, and violations of multiple sections of Texas state law.\n*The offender can have no disqualifying criminal history.\n*The offender must wait a certain period of time following a court order of dismissal and discharge before petitioning for the order.\n*The offender must not have been convicted of, or placed on adjudication for, any criminal offense during a specific time period.\nBeing able to meet all of these requirements will entitle the offender to petition for, and likely receive, an order of nondisclosure. To obtain this, a petition must be filed with the court clerk who handled the offense which placed you on deferred adjudication. The fees for the petition vary by county, but upwards of $280 can be paid.", "pred_label": "__label__POS", "pred_score_pos": 0.9766051173210144}
{"content": "Visible light photocatalysis of Ag/AgCl/BiVO4 was synthesized by the selective doping of Ag/AgCl on (040) facet of monoclinic BiVO4. The as-prepared catalyst was characterized by XRD, SEM, EDS, UV-Vis DRS, XPS, and nitrogen adsorption studies. The photocatalytic activity of Ag/AgCl/BiVO4 was tested on the removal of a pharmaceutical drug carbamazepine (CBZ). A CBZ removal of 70.6% and COD and TOC decrements of 21% and 9.6% were achieved within a reaction time of 4 h. The results demonstrated that the addition of oxidants improved the photocatalytic activity (97.9% and 100% CBZ removal in the presence of H2O2 and PS). Photocatalytic mechanism of the Ag/AgCl/BiVO4 plasmonic composite photocatalyst under visible LED light irradiation was clarified and O-2(center dot-) radicals were found as the most dominant radicals. The toxicity decrement was 21.7% for the treated CBZ solution. Furthermore, the Ag/AgCl/BiVO4 heterostructured photocatalyst has high stability under visible light irradiation which could be reused after three consecutive runs with a small Ag leaching (< 0.1 ppm).", "pred_label": "__label__POS", "pred_score_pos": 0.8751698136329651}
{"content": "Rapid urbanization is the most significant demographic shift taking place. By the year 2050, it is predicted that 70% of the world population will...\nSub-Saharan Africa\nThe Syrian conflict has resulted in over 2.3 million child refugees in the Middle East and the prevalence of early marriage has reportedly increased among displaced Syrian families. This study explores the underlying factors contributing to child marriage among Syrian refugees in Lebanon with the goal of informing community-based strategies to address the issue.\nAbulrazzaq Al-Saiedi works as a research manager, Iraq country expert, and policy advisor with HHI on a project called\nAssessing Conflict-Affected Communities’ Perceptions and Attitudes about Peace and Justice in Iraq. Al-Saiedi is an expert in transitional justice and rule of law initiatives in the MENA region.\nThe course is aimed at providing basic knowledge about the role and functions of the Food Security Cluster, both at global and national level. It is also aimed at building basic Cluster Coordination competencies and providing tools for efficient Food Security Cluster Coordination.\nCrisis Code: Humanitarian Protection in the Digital Age. Panel 1: Humanitarian Threats in the Age of Cyberwar, part of our #SwissTouch events at swissnex San Francisco.\nInformation communication technologies and the data they produce are transforming how natural and manmade disasters alike unfold. These technologies are also affecting how populations behave and organizations respond when these events occur.\nCrisis-affected populations and humanitarian aid providers are both becoming increasingly reliant on information and communications technology (ICTs) for finding and provisioning aid. This is exposing critical, unaddressed gaps in the legal and ethical frameworks that traditionally defined and governed the professional conduct of humanitarian action.", "pred_label": "__label__POS", "pred_score_pos": 0.5534093379974365}
{"content": "Bird, W. A., Bowling, A. M., & Ball, A. L. (2020). Civic Engagement, Autonomy, and Reflection: Factors Influencing Youth’s Self-Perceived Civic Responsibility.\nJournal of Agricultural Education, 61(1), 203-220. doi: 10.5032/jae.2020.01203\nThis study’s purpose was to determine the influence of involvement level, autonomy, and reflection during FFA civic engagement activities on students’ self-perceived civic responsibility levels. The study utilized a quasi-experimental, non-equivalent comparison group design. The treatment consisted of two groups: an experimental reflection group and a control group. Four school-based agriculture programs agreed to participate, providing a time and place sample of 282 respondents. Simultaneous multiple linear regression models explained significant variance in students' levels of self-perceived civic responsibility scores using a linear combination of involvement level, autonomy, and structured, guided reflection. Data analysis revealed positive, statistically significant relationships between the autonomy and reflection variables and youths’ perceived levels of civic responsibility. These findings can inform educator practices for designing FFA civic engagement programming.", "pred_label": "__label__POS", "pred_score_pos": 0.9550403952598572}
{"content": "Peter came to Jesus and asked him if he should forgive his brother or sister up to seven times. Jesus answered,\"I tell you, not seven times, but seventy-seven times. Then he told a parable describing the kingdom of heaven:\n...the kingdom of heaven is like a king who wanted to settle accounts with his servants. As he began the settlement, a man who owed him ten thousand bags of gold was brought to him. Since he was not able to pay, the master ordered that he and his wife and his children and all that he had be sold to repay the debt. \"At this the servant fell on his knees before him.'Be patient with me,' he begged, 'and I will pay back everything.' The servant's master took pity on him, canceled the debt and let him go.\n\"But when that servant went out, he found one of his fellow servants who owed him a hundred silver coins.He grabbed him and began to choke him. 'Pay back what you owe me!' he demanded. \"His fellow servant fell to his knees and begged him, 'Be patient with me, and I will pay it back.' \"But he refused. Instead, he went off and had the man thrown into prison until he could pay the debt. When the other servants saw what had happened, they were outraged and went and told their master everything that had happened. \"Then the master called the servant in. 'You wicked servant,' he said, 'I canceled all that debt of yours because you begged me to. Shouldn't you have had mercy on your fellow servant just as I had on you?' In anger his master handed him over to the jailers to be tortured, until he should pay back all he owed. \"This is how my heavenly Father will treat each of you unless you forgive your brother or sister from your heart.\" (Matthew 18:23-35)\nYikes! It looks like we'd better get busy and show mercy to our brothers and sisters or else we're in real trouble!! But I think we need to look a little deeper than that. I know I need to look deeper.\nThe king in the parable asked the servant, \"Shouldn't you have had mercy on your fellow servant just as I had on you?\" Hey, that sounds like the Golden Rule: \"Do unto others, as you would have them do unto you.\" How are we doing with that? Sometimes it's hardest to extend grace to those who are closest to us, even within our own homes, maybe especially if we're confined to our homes during the pandemic (and during an election year). But more than likely, our loved ones are extending grace to us too, even if we're not aware.\nThis Sunday's anthem is titled \"The Wideness of God's Mercy\" by Frederick William Faber. Here is the first verse:\nThere's a wideness in God's mercy like the wideness of the sea;\nThere's a kindness in His justice, which is more than liberty.\nThere is welcome for the sinner and more graces for the good;\nThere is mercy with the Savior; there is healing in His blood.\nIf we are aware of how we have sinned against God (deserving his judgment) and the price that God paid to reconcile us with him, we might\nmaybe begin to grasp the unfathomable mercy and love and grace that he extends to us, at every moment. So it stands to reason that we should accept that grace and extend it to our brothers and sisters who have committed far lesser crimes against us.", "pred_label": "__label__POS", "pred_score_pos": 0.7657907009124756}
{"content": "Abstract\nBackground. Recent reports have highlighted possible decreases over time in obesity, particularly among children aged 2-5 years. Hispanic children experience significantly higher obesity rates, and less is known about trends for Hispanic children. Methods. A large healthcare system-based dataset from south Texas was used to analyze body mass index (BMI) values obtained clinically from 2009 through 2015. Age and race/ethnicity specific prevalence of overweight and obesity were calculated using CDC standards and trends were examined over time using regression analyses, and mapping software was used to identify geographic variation. Results. Hispanic children in south Texas experience levels of obesity (25.3%, 95% CI: 25.1-25.6) significantly higher than their white (16.6%, 95% CI: 16.0-17.2) or black (18.2%, 95% CI: 17.3-19.1) peers. Obesity in Hispanic children aged 2-5 years decreased from 18.5%, 95% CI: 16.6-20.5, in 2009 to 15.1%, 95% CI: 14.3-15.9, in 2015. Obesity in Hispanic adolescents was stable at 30.4%, 95% CI: 28.5-32.4, in 2009 and 31.3, 95% CI: 30.3-32.2, in 2015. Conclusions. While obesity decreased in the youngest age group of Hispanic children, south Texas continues to experience high levels of obesity that exceed national averages with significant disparities.\nASJC Scopus subject areas Endocrinology, Diabetes and Metabolism", "pred_label": "__label__POS", "pred_score_pos": 0.6841343641281128}
{"content": "You can clean your mattresses with vacuum with a HEPA filter system. However, just vacuuming the mattresses is not sufficient enough. You need professional help because regular vacuum cleaners suck out the dirt and soil and bring it close to the surface. This is more dangerous for the health of the users. So it is advisable to get your mattresses cleaned often by professional mattress cleaners.", "pred_label": "__label__POS", "pred_score_pos": 0.9938296675682068}
{"content": "Finding and Fixing Air Duct LeaksMost homeowners experience significant energy-efficiency losses through air leaks in their ductwork. But these leaks often can easily be found and repaired. Read more below about how you can start saving!\nThese warning signs may indicate that your ducts are not sealed properly:\nHot and cold spots throughout your home Higher summer and winter utility bills Stuffy and uncomfortable feeling in some rooms Ductwork is located in a crawlspace, attic or garage Wipe the ductwork to ensure proper bonding with the sealant Use a fibrous sealant with a fiberglass or foil tape to seal your ducts (no duct tape!) Spread duct mastic across the seams, joints, holes and cracks of your ductwork. Enhanced comfort with reduced stuffiness and temperature swings Better indoor air quality with fewer dust and debris particles Enhanced safety with no “backdrafting” Improved energy efficiency with significant savings on heating and cooling costs.", "pred_label": "__label__POS", "pred_score_pos": 0.9579964876174927}
{"content": "What is bycatch?\nFishermen sometimes catch and discard animals they do not want, cannot sell, or are not allowed to keep. This is collectively known as “bycatch.” Bycatch can be fish, but also includes other animals such as dolphins, whales, sea turtles, and seabirds that become hooked or entangled in fishing gear.\nFor NOAA Fisheries, bycatch refers to“discarded catch of marine species and unobserved mortality due to a direct encounter with fishing vessels and gear.” These unintentionally caught animals often suffer injuries or die.\nNOAA Fisheries is committed to continuing to reduce and minimize bycatch now and into the future. Our investment in bycatch reduction is spread across multiple program areas and laws including the Magnuson-Stevens Fishery Conservation and Management Act, Marine Mammal Protection Act, and Endangered Species Act.", "pred_label": "__label__POS", "pred_score_pos": 0.9999533891677856}
{"content": "On March 18, 2020, Queen’s University Library closed its physical facilities in response to the coronavirus pandemic. Since then, our online resources have remained available to support the university's academic and research mission. In recognition of the critical role that library resources play in research, including ongoing research into COVID-19, the library has developed a service to provide faculty and graduate researchers with limited access to print collections. A description of the sevice and instructions for submitting requests for print materials are now available on our website, with the first pick-up planned for early next week.\nThe plan, informed by public health guidelines and developed with staff and user safety as its core priority, provides access to print materials via a ‘curbside pick-up' at Stauffer Library which will be set up to maintain physical distancing. Principal investigators and faculty members will request access to print materials by submitting a written request following a consultation with a librarian to review their information need. Approval of requests will be made by the relevant Dean or delegate based on research priorities established to ensure on-site research activities are carried out safely.\nThis will be the first re-introduction of physical library service, albeit limited, and has been developed in alignment with the process required for those requesting to resume on-site research. The library will continue to work with university leadership and public health officials to review the potential for additional services adjustments, as evolving public health guidelines allow.\nThis message was first posted to the Queen's University Library website.", "pred_label": "__label__POS", "pred_score_pos": 0.8934766054153442}
{"content": "Life Sciences Call 2018 - Linking Research and Patients' Needs - Linking Research and Patients' Needs / LS18-090\nAbstract: Cardiovascular disease (CVD) is the most common cause of mortality in Europe. Despite well-controlled levels of low density lipoprotein cholesterol (LDL-C) CV events occur at cumulative incidences of >20% at 5 years. These observations stimulate search for other mechanisms that account for CV events. In this translational biomedical research approach we will combine an academic investigator-initiated trial funded by Inselspital Bern aiming to understand the impact of LDL-C lowering on atheroma volume in high-risk ACS patients, with a basic science project addressing the innate immune system. This placebo-controlled trial will be a unique resource of tissues from a clearly defined patient cohort. By combining the strength and expertise of a physician-scientist and a basic atherosclerosis researcher, the proposed project will dissect unexplored, fundamental processes raising the risk for atherothrombosis beyond the lipid hypothesis of atherosclerosis. Innate immunity gives rise to sophisticated processes, which can be explored in the unique setting of this trial. We will analyse signaling pathways leading to neutrophil extracellular trap (NET) formation, investigate impact of oxidation epitope-specific IgM and microvesicles carrying oxidation-specific epitopes from different cellular origins, and study their ability to stimulate neutrophil effector function. We expect to extend understanding of CVD beyond well-described LDL-C-dependent pathways, to benefit high-risk patients.\nScientific disciplines: 302030 - Internal medicine (50%) | 302032 - Cardiology (25%) | 301902 - Immunology (25%)", "pred_label": "__label__POS", "pred_score_pos": 0.9335756301879883}
{"content": "When planning a construction project, you should have the right equipment for it. If you don't, the construction project may delay and lead to money and time wastage. A Posi-Track is one of the construction machines you may need to hire to complete your project in good time. But before you hire the track loader, you need to ask yourself these questions.\nWill It Be Safe to Use?\nIf you don't consider the safety of the construction equipment you intend to hire, things might go wrong on your side. You first need to go through the safety laws in your area. Although some of the stringent safety laws don't apply to some tracks, they usually apply to most of them.\nAssess the construction site to know the level of certification you need and the safety measures you should maintain. If you don't do it, you may sustain unnecessary injuries and damages. But with the right safety mechanisms in place, you will complete your construction project without casualties.\nIs the Track Adaptable?\nAdaptability is one of the things you should consider when hiring a Posi-Track. Most track loaders use various attachments to enhance efficiency during the construction process. However, some of the attachments might not be suitable for some construction projects. In this case, you should find out if the attachments can be customised and if the track has the necessary customisation options.\nIf a standard model can't get the job done, is the track flexible enough to accommodate some special models? An efficient track should offer maximum adaptability to help you save time and money. It should also be flexible to accommodate special buckets, trenchers, rakes, forks and brooms.\nWill It Attract Some Additional Costs?\nWhen hiring a track loader, you should ask for an initial quote to know whether it's within your budget. However, you shouldn't stop at the figures you get. You should also ask the track operator whether you should expect some extra costs as you go on with your construction project.\nSometimes, the company or operator may not indicate every cost when giving the initial quote before they visit the site. Ask whether you should fuel the track, buy lubricant, pay the operator or buy some safety gear. Such costs might not reflect in the initial quotation, but they might appear later. So do all you can to get transparent upfront to help you organise your budget.\nHiring a Posi-Track is far much cheaper than buying one for your construction project. However, the hiring process might be tricky if you don't have some questions to guide you. So ensure you understand everything about additional costs, flexibility or adaptability and safety before you hire the track. Look for someone near you who offers Posi-Track hire.\nShare", "pred_label": "__label__POS", "pred_score_pos": 0.5667986869812012}
{"content": "The U.S. District Court for the Southern District of New York, in\nFisher v. Aetna Life Ins. Co., has upheld its prior determination that a beneficiary was required to meet the ACA’s family out-of-pocket cost-sharing limit rather than the individual limit. In reaching this outcome, the court concluded that HHS regulations interpreting the ACA’s cost-sharing provisions were not retroactively applicable. Law. Under the ACA, annual cost-sharing under a non-grandfathered group health plan may not exceed certain ACA limits on an individual’s out-of-pocket costs. HHS regulations issued in 2015, which became effective in 2016, say that the ACA’s annual cost-sharing for self-only coverage should apply to individuals with either self-only or non-self-only coverage. Under these regulations, plans could not require individuals with family coverage to spend more than the out-of-pocket limit for self-only coverage.\nUnder Second Circuit precedent, an interpretive rule may be applied to a matter retroactively, but a legislative rule may not. An interpretive rule is one that clarifies an existing rule or regulation, while a legislative rule alters the law in some way.\nFacts. In Fisher, the plaintiff was a beneficiary under an non-grandfathered ERISA group health plan sponsored by her husband’s employer. The plan contained the following cost-sharing provisions: Before reaching a $4,000 deductible, covered individuals ( , participants and beneficiaries) were responsible for their medical expenses. i.e. After reaching the out-of-pocket limit, the plan paid 100% of the covered amount for the rest of the plan year.\nIn 2015, the plaintiff purchased a drug prescribed by her treating physician. The claims administrator denied the plaintiff’s claim for benefits, concluding that the family, rather than individual, out-of-pocket limit applied to the plaintiff’s claim because she had family coverage.\nIn turn, the plaintiff sued the claims administrator in federal district court to challenge the claim denial. The district court determined that the claims administrator’s determination was arbitrary and capricious and remanded the matter to the claims administrator for further review. On review, the claims administrator reached the same conclusion. The beneficiary again challenged the claims administrator’s determination, and this time the court ruled in favor of the claims administrator. The plaintiff responded by filing a motion to request that the court reconsider its decision in the matter.\nDistrict Court. The plaintiff asserted that in determining she was required to meet the family and not the individual out-of-pocket limit, the court had ignored the HHS regulations’ interpretation of the ACA cost-sharing requirements. As support for this position, the plaintiff cited HHS regulations which provide that the ACA’s limits for self-only coverage would apply to individuals with s both self-only and family coverage. The outcome of the plaintiff’s challenge depended on whether HHS’s 2015 regulations applied retroactively.\nThe district court denied the plaintiff’s motion for reconsideration. In reaching this determination, the court concluded that it did not fail to consider HHS regulations interpreting the ACA’s cost-sharing provisions when it interpreted the terms of the plan because the regulations were not retroactive. The court further noted that the ACA does not specify which out-of-pocket limit should apply when an individual has family coverage.\nIn reaching this conclusion, the court explained that:\nThe rule contained in the regulations involved a change, as evidenced by the ACA’s silence on which limit applied in this situation and the fact that insurers typically required individuals to meet the family out-of-pocket limit before the regulation went into effect. The regulations were issued using the notice-and-comment rulemaking process under the Administrative Procedure Act. HHS indicated that the rule applied prospectively.\nBecause the court found the regulations were not retroactive, the court concluded that it did not fail to apply the ACA’s cost-sharing provisions when it interpreted the plan’s terms to require the plaintiff to meet the out-of-pocket limit for family coverage.", "pred_label": "__label__POS", "pred_score_pos": 0.8085488080978394}
{"content": "From the Editor\nLast week, the Senate voted 52 to 29 in favour of Bill C-45, clearing the last hurdle for marijuana legalization. The federal government is aiming for implementation in the fall.\nSo, what now?\nIn the first selection, the University of Toronto’s Tony P. George\net al. discuss a “framework” for cannabis policy post-legalization. This Canadian Journal of Psychiatry perspective paper is prescriptive, aiming to reduce the negative effects of the legal change. They make six recommendations, including a national strategy for education.\nAlso, in this week’s Reading, we consider the life and psychiatric contributions of Charles Krauthammer, who died last week at age 68. Dr. Krauthammer is best known for his political commentary, but he had a career in psychiatry before becoming a prominent essayist, and penned a classic paper on “secondary mania.”\nPlease note that there will be no Reading next week.\nDG", "pred_label": "__label__POS", "pred_score_pos": 0.7690480351448059}
{"content": "UC Santa Cruz Inferring Genetic Co-dependencies To Identify New Vulnerabilities In Cancer Author(s): Matthew, Thomas James Advisor(s): Stuart, Joshua et al. Abstract\nTranslation of cancer genomic data into cancer therapies and companion\ndiagnostics remains a primary challenge in personalized medicine. Much of this\nchallenge is due to the difficulty of identifying genetic co-dependencies that lead to\nclinically actionable drug targets. Targeting many of the known essential gene\nproducts are not always selectively efficacious because these targets may be\ncommon to both malignant and benign cells. However, essential genes that are\nassociated with particular genomic alterations in cancer cells, like those from\nsynthetic lethality, can potentially provide a source of tumor-specific drug targets.\nTo help aid novel drug discovery, I developed a computational approach called\nCLOvE, a multi-omic approach that identifies co-dependencies in pairs of genes.\nThese co-dependencies are inferred from context-dependent changes in\nexpression, where CLOvE assigns high scores to those genes with the greatest\ncompensatory change in expression. These scores may suggest synthetic lethal\ninteractions, which may uncover clinically actionable essential genes. These\nmethods were developed in CCLE cell lines and validated with RNAi and CRISPR\nviability data. CLOvE identifies meaningful expression changes, assigns high scores\nto known essentials, reveals known synthetic lethal connections, and implicates\nmany possible new connections. This approach could provide a tool to accelerate\nboth target discovery and biomarker discovery, to develop drugs suitable for a\nspecific cancer, and identify and stratify patients who may benefit from these\ntreatments.", "pred_label": "__label__POS", "pred_score_pos": 0.9789556264877319}
{"content": "“In fulfilling our mandate over the 2019 – 2022 period, our National Standardization Strategy focuses on high priority Products and Services, including Construction Goods. The standardization of these products contributes towards the overall mitigation against threats associated with natural disasters such as earthquakes, tropical storms and hurricanes which are known to affect our region. The standardization of these goods can also support the development of a National Building Code which has been requested by various Stakeholders over the past years but even more recently following the 2018 seismic activity.”\nThese were the words of Derek Luk Pat, Executive Director, of the Trinidad and Tobago Bureau of Standards (TTBS), as he addressed participants at the Opening Ceremony of the National Stakeholder Meeting on the enforcement of the National Compulsory Standard, TTS 588:2015, for Horizontal Core Hollow Clay Blocks.\nThe meeting was held on Thursday 21\nst March 2019, at TTBS in Macoya, and included representatives from clay block manufacturers, the construction industry, regulatory agencies, governmental organizations, consumer protection agencies and distributors.\nThe stakeholders were informed that a Moratorium Period would commence on the 21\nst March 2019 and conclude on the 20 th June 2019. Following the moratorium, all applicable blocks used within Trinidad and Tobago, must comply with the specifications set out in the Standard. Furthermore, compliance must be demonstrated via certification from TTBS which is the regulatory authority. Certification of the blocks will ensure that construction companies, contractors, consumers and home owners will have an adequate level of protection and confidence when purchasing blocks for construction projects.\nThese activities contribute to the development of the National Quality Infrastructure (NQI). The NQI includes all systems for standardization, testing, inspection, certification, accreditation and measurement. It is critical in ensuring that products, services and persons conform to industrial, national, regional and international requirements. As a result it also has a significant impact on National Development, Trade Competitiveness and Socio- Economic Health. At the meeting it was noted that in regard to the development of the NQI, TTBS is assisting the Ministry of Trade and Industry (MTI) to institute the 2018-2030 National Quality Policy and Implementation Plan which was approved by GORTT in April 2018.\nThis initiative forms part of TTBS’ mandate under the Standards Act (Act No.18 of 1997) as the National Standards Body and National Quality Certifying Body. Against this backdrop, TTBS is committed to improving competitiveness and promoting sustainable development through the formulation, promotion, and application of standards and conformity assessment activities.", "pred_label": "__label__POS", "pred_score_pos": 0.8684056401252747}
{"content": "Are you searching for an energy-efficient way to heat your home? A boiler is sure to do the trick. Hire a technician at Living Water Plumbing, LLC for boiler installation. Our team will go above and beyond to install your boiler swiftly and efficiently. You have direct access to heat with no fuss.\nSchedule your boiler installation in Casper, WY today.\nA broken boiler leaves your home cold and uncomfortable. Keep your home warm throughout the winter with our boiler repair. Our team will inspect your unit to determine what's causing the complications. Once we've found the source of the trouble, we'll discuss repair or replacement options.\nIf your boiler is on the fritz, call now to schedule your boiler repair with one of our technicians.", "pred_label": "__label__POS", "pred_score_pos": 0.5812885761260986}
{"content": "Abstract\nScholars know little about families' experiences when receiving related services and how these services affect the shift from a family-centered to an educational program. In this qualitative interview study, the authors explored the transition experiences of six families over a 3-month period, focusing on the role of related therapy services and therapists. In the metatheme titled The Outsiders, the authors discuss these families' views of their changing roles as their children enter preschool programs. Families in this study felt removed from their former role as an integral member of their children's intervention team once their children entered school. Based on these families' reported experiences, the authors propose strategies for professionals to improve their communication with parents to help them during this transition.\nKeywords children with disabilities family centered infants occupational therapy related services toddlers early intervention Preschool children ASJC Scopus subject areas Education Rehabilitation", "pred_label": "__label__POS", "pred_score_pos": 0.7041452527046204}
{"content": "Macrophages make up a crucial aspect of the immune system, carrying out a variety of functions ranging from clearing cellular debris to their well-recognized roles as innate immune cells. These cells exist along a spectrum of phenotypes but can be generally divided into proinflammatory (M1) and anti-inflammatory (M2) groups, representing different states of polarization. Due to their diverse functions, macrophages are implicated in a variety of diseases such as atherosclerosis, lupus nephritis, or infection with HIV. Throughout their lifetime, macrophages can be influenced by a wide variety of signals that influence their polarization states, which can affect their function and influence their effects on disease progression. This review seeks to provide a summary of how GM-CSF and M-CSF influence macrophage activity during disease, and provide examples of in vitro research that indicate competition between the two cytokines in governing macrophage polarization. Gaining a greater understanding of the relationship between GM-CSF and M-CSF, along with how these cytokines fit into the larger context of diseases, will inform their use as treatments or targets for treatment in various diseases.", "pred_label": "__label__POS", "pred_score_pos": 0.8780904412269592}
{"content": "Should you reduce or replace your calories? Not all calories are equal\n. While all calories contain the same amount of energy, calories from different foods react differently. Consider a donut, a kale salad with olive oil dressing, and a broiled chicken breast.\nThe donut contains calories from sugar that your body immediately digest and absorb into your bloodstream. Once there, the blood sugar triggers an insulin response, followed by a cortisol release. If your body does not quickly burn these calories, your body converts them as body fat. One donut can cause many problems: two donuts double the sugar, the calories, and the body fat.\nThe kale in your salad provides calories from complex carbohydrates and fiber.\nKale is slowly digested, even requiring additional calories for the digestive process. Also, it provides bulk and fiber that may pass through your digestive system without being fully digested or absorbed.\nThe olive oil in your dressing is a fat (lipid). In this case, it a healthy fatty acid that remains undigested in your digestive tract until it reaches your small intestine. After digestion, your intestines absorb olive oil and burn it as fuel or store it in your liver for future use. Olive oil and avocados are examples of healthy fats, compared to the unhealthy fats found in butter, cheese, red meat, and full-fat dairy products.\nThe broiled chicken breast provides calories from lean protein.\nThe digestion process begins in your mouth as you chew and ends in your stomach. The acids in your stomach break proteins down into amino acids. Your body absorbs the protein and then uses it to build or repair your body. Consequently, the human body does not burn protein as fuel when you eat carbohydrates or fats.\nIf your goal is a lean, muscular or toned body with less stored body fat, doesn’t it make sense to consume fewer calories from simple carbohydrates (donuts) and more calories from complex carbs (kale), lean protein (chicken), and healthy fatty acids (olive oil)?\nYou may have also been told that the only way to lose weight is to create a calorie deficit. Both options are effective, but there is a third option that will help boost your weight loss. Replace “bad” calories from sugars and saturated fats with “good” calories from complex carbohydrates, Omega-3 fatty acids, and lean proteins.\nInstead of choosing between replacing or reducing calories, do both!\nReduce the number of calories you eat daily to create your calorie deficit and replace the empty, junk calories with healthy calories. Start by eliminating sugars (cookies, donuts, cakes, etc.) and saturated fats (butter, cheese, and ice cream). Also, eat more fruits, vegetables, and whole grains: foods filled with complex carbohydrates and fiber. Doing so will fill your stomach and leave you satisfied with nutritious foods and fewer calories!", "pred_label": "__label__POS", "pred_score_pos": 0.5297108292579651}
{"content": "Shifting two sliding sleeves using Well Key 325\nWell typeProducer offshore\nMax. deviation31.92°\nDepth SSD #15,173 ft (1,577m)\nDepth SSD #24,916 ft (1,498m)\nMax. pressure2,300 psi\nMax. temperature256°F (125°C) Background\nA well designed with an upside-down completion was causing problems for an operator in Indonesia. The operator needed to shift two 4.562″ sliding sleeves in the 5-1/2” lower completion. To do so, the toolstring needed to pass through the 4-1/2” upper completion, where a 3.688” nipple profile was restricting passage. Slickline was impossible. This would require the time-consuming and costly pulling of the upper completion along with the associated deferred production.\nWelltec® was called upon due to the operator’s previous experiences with our solution package for mechanical manipulation. The Well Key® design allows it to pass restrictions, as its keys are only extended when positioned accurately in the well to lock into the sliding sleeve profile.\nOperation\nThe Well Key 325 Extended Reach was selected to pass through the restriction and reach the sliding sleeve shifting profile. Prior to mobilization, a SIT was conducted at Welltec’s Jakarta facility and the key profile was revised to match the sliding sleeve profile perfectly. The operator was satisfied that the tools would work properly and recommended to reduce the force on the Well Stroker® from 33,000 lbs to 15,000 lbs to avoid damaging the sleeve. During the operation, the toolstring passed through the restriction with no complications.\nThe Well Key profile was positioned with pinpoint accuracy above the sliding sleeve profile and then activated. The Well Tractor® powered up to engage the Well Key profile to the shifting profile. The Well Stroker, configured with 15,000 lbs force, anchored in position on the 5-1/2” 20# blank pipe above the sliding sleeve and powered up to stroke down and shift open the sleeve. It required two strokes to fully open the sliding sleeve door. Once the first sleeve was opened the well was unloaded and the second sleeve opened a few days later.\nAchievements\nThis was the first sliding sleeve manipulation using the Well Key 325 and the operator was pleased with the outcome. It took only ten hours from rig up to rig down to open the first sleeve and the second was opened in only eight hours. The Well Key easily passed through the restriction to perform the task. This saved the operator from having to pull the upper completion and avoiding the deferred production these alternatives would have cost.\nThe operation demonstrated the agility of the Welltec solutions. Even with the upside-down completion, the Well Stroker-Well Key combination brought the well on-line on time and targeted schedule. The well is now producing 10MMsfp/D gas at 18% choke.\nQuote\nThis saved the operator from having to pull the upper completion and avoiding the deferred production these alternatives would have cost.", "pred_label": "__label__POS", "pred_score_pos": 0.9563628435134888}
{"content": "The latter half of March has brought plenty of chatter regarding severe price retrenchment in several previously hot momentum sectors.\nThat list is populated most notoriously by biotech stocks and exchange traded funds, but familiar constituents also include Internet, social media and solar ETFs. [Momentum Stocks, ETFs Take a Beating]\nRapid deterioration in momentum sectors should serve as a reminder that momentum investing, particularly with ETFs, does not always mean direct bets on glamorous but volatile high P/E growth sectors. Actually, momentum can be derived from inexpensive sectors perceived to be value bets. [Marry Momentum With This ETF]\nTake the energy sector as a prime example of a perceived value bet that is now displaying some noticeable, positive momentum. Some investors have already hear that ETFs such as the\nEnergy Select Sector SPDR (NYSEArca: XLE) and the Vanguard Energy ETF (NYSEArca: VDE) are being boosted by compelling valuations. Another option for seizing the energy sector’s new found “momo” is with the PowerShares DWA Energy Momentum Portfolio (NYSEArca: PXI).\nThe $196 million PXI is one of the 10 PowerShares ETFs that recently made the transition to Dorsey Wright momentum-driven indices. Although PXI fits the definition of a smart beta ETF, the fund is not excessively allocated to value or small-cap stocks. Small-caps account for about 28% of the ETF’s weight while large-caps represent 40%.\nImportantly, many of the large-cap energy names that are viewed as value stocks are not a significant percentage of PXI’s weight. For example, Chevron (NYSE: CVX) is just 3% of the fund’s weight while Exxon Mobil (NYSE: XOM) and Occidental Petroleum (NYSE: OXY) are not found in PXI.\nInvestors should not PXI is a highly focused ETF compared to competitors such as XLE and VDE. PXI holds just 30 stocks, or not even 20% of the number holdings found in VDE. The smaller lineup is not holding PXI back.", "pred_label": "__label__POS", "pred_score_pos": 0.6833037734031677}
{"content": "Environmental and Occupational Epidemiology Online Course\nMost diseases are either caused or influenced by environmental factors. Understanding these is essential to design effective prevention programs.\nEnvironmental epidemiology provides a scientific basis for studying and interpreting the relationships between the environment and population health. Occupational epidemiology deals specifically with environmental factors in the workplace.\nProceed through the content in chronological order, and click the “Complete” button at the end of each section. Note: To view the full width of each page without scrolling left to right, please collapse the left-side menu using the arrow in the top left of the page. This learning experience requires about five hours to complete, and is accredited for five hours of CME.", "pred_label": "__label__POS", "pred_score_pos": 0.5370953679084778}
{"content": "Tourism in South Africa had mixed results in 2018/19. The country recorded 10.4 million international tourist arrivals, a 0.6% decrease from the previous year.\nAfrica continues to be our largest source market, accounting for 74% (7.7 million) of these visitors. However, this region was only responsible for 40% of the foreign tourism revenue generated last year according to South Africa Tourism’s annual report.\nThe declining visitor numbers can be attributed to negative perceptions about safety and security, and the water crisis, particularly in Cape Town.\nTourism injected R116,9 billion into the South African economy in 2018/19 through the direct spend of both international and domestic tourists. This represents an increase of 12.7% over the R103,8 billion in 2017/18.\nInternational tourists contributed 75% (R87,4 billion) direct spend in South Africa in 2018/19. Foreign direct spend by international tourists grew by 6.6% over R82,0 billion in 2017/18 despite the 0.6% decline in international tourist arrivals.\nDomestic tourists, on the other hand, contributed R29,5 billion in the year, a growth of 35.7% over the R21,7 billion in 2017/18.\nThe economic significance of tourism is further supported by tourism’s contribution to GDP. World Travel and Tourism Council (WTTC) estimates that the economic impact of tourism in South Africa (measured through tourism’s total contribution to GDP) was R425 billion (8.6% of the total economy).\nVisitor exports is estimated at R126,7 billion or 9.2% of total South African exports. WTTC also estimates that tourism contributed approximately 1,5 million jobs to the total South African economy which represents about 9.2% of the total employment in the country.\nOn average, international tourists stayed 11.7 nights in South Africa in 2018/19, down from 12.4 nights in 2017/18. Tourists from the Middle East and Africa stayed for fewer nights in 2018/19 than 2017/18.\nGauteng remained the most visited province with a 36.2% share of total international arrivals. It is the primary gateway for international tourists arriving in South Africa. It is also a major destination for tourists from neighbouring countries who mainly travel to Gauteng to shop.\nLimpopo remained in second place with 21.2% a share driven by growth from its key source markets of Zimbabwe and Botswana. Other major source markets for Limpopo are the United States of America, Germany and the UK.\nThe Western Cape is the third most visited province with a 16.3% share of total international arrivals.\nThe major source markets for this province are the UK, Germany and the United States of America, followed by Namibia and France.\nThe Eastern Cape received 4 % of visitors.\nIn 2018/19, there were 18,7 million domestic trips taken in South Africa. This was a 12.7% increase from 2017/18.\nThey contributed R29,5 billion in direct spend to the country’s economy with visiting friends and relatives being the biggest driver\nAccording to the South African Tourism domestic brand tracker surveys, visiting friends and relatives continues to be the main reason for domestic travel (53%) and 47% of travellers stated friends/family recommendations being a reason for their travel choices.\nPackages that include beaches and coastline travel experiences have had the best sales. According to sentiment analysis, most conversations on social media about domestic travel are centred around beaches.", "pred_label": "__label__POS", "pred_score_pos": 0.6401277780532837}
{"content": "Daily work might include preparing or examining financial documents, creating or assessing budgets and long-term financial plans, and advising organizations and individuals on financial decisions.\nAs a public accountant, you can focus on two broad areas: tax and audit. As your career progresses, you’ll probably want to become a specialist in one or more niches within these areas. For example, you could specialize in performing audits of not-for-profit organizations or benefit plans, providing tax planning for estates, or helping businesses address international taxation issues. You might also choose to specialize in a skill that can apply to multiple areas, such as forensic accounting.\nWhile each public accounting firm is different, you’re likely to encounter a similar work environment at the position you choose. Some common elements include:\nHours\nMost public accountants are full-time employees who work a minimum of 40 hours per week. Many work significantly more, especially during the busy tax season. If balancing work with family and personal demands is important to you, look for a firm that offers flexible schedules and keeps overtime hours to a minimum when possible. A few accounting firms even consider part-time schedules in some cases.\nTravel\nTravel is often part of a public accountant’s job requirements, although not always. Audit engagements tend to demand more travel than tax work, but again, this can vary based on the client’s needs and the firm’s location and policy. Some public accounting positions don’t require any travel at all. Choosing a non-audit area of focus is a good idea for new accountants who want to avoid the need to travel for their job.\nLocation\nPublic accountants can work at their firm’s offices or those of the client, or even remotely from another site. In rare cases, accounting firms may allow accountants to work from home some or most of the time. As with travel, audit professionals are more likely to spend time at the client’s site, either locally or in another city, while tax accountants frequently work in their own firm’s offices.\nPublic accounting is a challenging and rewarding profession that’s ideal for inquisitive, detail-oriented people who enjoy helping others. If this sounds like the right fit for you, we encourage you to explore the many advantages of a career with PBMares.", "pred_label": "__label__POS", "pred_score_pos": 0.8118177652359009}
{"content": "Authors\n1\nFood and Drug Laboratory Research Center, Food and Drug Organization, Ministry of Health and\nMedical Education, Tehran, Iran\n2\nDepartment of Food Science and Technology, Varamin Branch, Islamic Azad University, Varamin, Iran\nAbstract\nSodium benzoate and potassium sorbate are two major chemical preservatives which are used in Doogh (Iranian traditional dairy drink). In this study, a total of 27 commercial brands of highly consumed of Doogh samples were analyzed. The means and standard deviation for concentration of these preservatives based on HPLC results for analysis of benzoate and sorbate were 195·9 (SD 1·8) and 328·8 (SD 2·1) mg.Kg-1 respectively. The minimum and maximum of benzoate content in various brands were 18.3 and 2345.1 mg.Kg-1 and for sorbate were not detected and 4961.3 mg.Kg-1 respectively. The study revealed that there was not significant difference in preservative concentration in the samples that belonged to various dates. However, a few samples had a high preservative concentration, which could be a risk factor for human health, especially when their intake was being occurred by various foodstuffs simultaneously.\nKeywords", "pred_label": "__label__POS", "pred_score_pos": 0.6342726945877075}
{"content": "During my investigations, I highlighted three innovations, all of which serve the production of a final product, sheep kefir. This product contains a unique added value and involves several innovational opportunities. I examined the complex economic analysis of the innovations and technological elements investigated with respect to revenues from the sale of sheep milk, sheep cheese (kashkaval) and sheep kefir. The kashkaval-type sheep cheese does not contain sufficient added value to cover the costs of innovational investments. Investigating the innovational activity for developing sheep kefir and for its market introduction, its cash flow balance becomes positive already in the second year after realization, and is able to generate significant profit.", "pred_label": "__label__POS", "pred_score_pos": 0.9579975605010986}
{"content": "About Event ABOUT THE ALLOGENEIC CELL THERAPIES SUMMIT\nDespite the significant breakthrough represented by autologous cell therapies in the field of cancer immunotherapy, challenges remain. Autologous cell therapies require bespoke manufacturing processes resulting in\nhigh costs, manufacturing failure in some patients and delay in availability of treatment.\nAllogeneic cell therapies can address these issues using healthy donors and scaled-up manufacturing processes. However, several key challenges still need to be overcome such as avoiding GVHD and avoiding elimination by the host immune system.\nBringing together both\nimmunotherapy and regenerative medicine leaders, the Allogeneic Cell Therapy Summit is focused on the clinical and commercial development of engineered allogeneic cell therapies with improved manufacturing and commercialization to benefit patients in need.\nJoin industry leaders to:\nExplore automation to reduce the cost of allogeneic cell therapies Address the need for effective cold chain supply to ensure allogeneic cell therapies are delivered to patients without losing desired characteristics Discover means to commercialize allogeneic cell therapies with effective scale-up/scale-out Assess the capabilities of genetic engineering to create bespoke allogeneic cell therapies Highlight the need for comparability and analytical tools to assist process development", "pred_label": "__label__POS", "pred_score_pos": 0.986545741558075}
{"content": "Given that a COVID-19 vaccine is expected to become available in limited quantities from >April 2021, India must have a strategy in mind to vaccinate the population in the shortest possible time. We propose that COVID-19 vaccination be carried out in a mission mode \" 'National COVID Vaccination Mission' (NCVM) \" similar to the exercise of holding the General Election, with a target to cover 5o percent of the population (approximately 70 crore) by December 2021.\nThe government and other stakeholders are focusing on issues related to vaccine procurement and distribution and cold chain issues. However, despite all this planning, we believe that if there is a shortage of human resources to administer the vaccine, the timeline for vaccinating the desired percentage of the population could get skewed. This will hurt the vaccination campaign. Here we present a simple strategy to secure human resources required to vaccinate people of India in a time-bound manner.\nThis pandemic has already harmed the Indian healthcare delivery systems including surgical procedures, non-COVID-19 medical Out-Patient (OPD) treatments as well as routine medical checks including regular immunisations. By some accounts, over ten lakh children have >missed routine required immunisations while OPD treatments for all patients, including essential ones for oncology patients, have dropped by more than 80 percent. The numbers for institutional childbirth have dropped sharply. Under-staffed and under-funded, the existing Indian healthcare infrastructure is now under significant pressure and threatening to crack.\nAssuming a single vaccination takes 20 minutes and a working period of eight hours per day, a worker would be able to vaccinate around 1,900 patients in about three months and it would require a pool of four lakh members of staff dedicated only to the COVID-19 vaccination to cover the targeted 70 crore population in six months.\nIn this scenario, we believe that it is not desirable to further stress the existing healthcare system by diverting human resources from there to administer Covid-19 vaccines. We believe, it is better to create a separate pool of human resources for this mission by calling on those students who are in their penultimate and final year of MBBS, BDS, AYUSH doctoral, nursing, pharmacy and other paramedical programs.\nThis NCVM exercise should be conducted on similar lines as the National General Election with booths being created across the country, with student professionals administering the vaccine, supported by deputed government (non-medical) officials to carry out administrative duties.\nPresently, there are 529 medical colleges in India, churning out around 80,000 MBBS doctors every year. Additionally, 26,000 students complete their Bachelor in Dentistry, 55,000 nurses and 30,000 AYUSH doctors graduate annually. If we consider the penultimate and final year students from all the above courses, the total pool will aggregate to >around four lakh (semi) trained medical professionals \" without considering other paramedical students as well as pharmacists (who also number around four lakh annually). This would create a workforce that may arise to the task at hand,\nviz vaccinating 70 crore people in six months.\nIt is beneficial if these students are roped into the COVID-19 vaccination system for a three-month 'field internship' stint as part of their formal academic curriculum. Besides taking care of their travel logistics, the students could be compensated through an honorarium and/or academic credits for this internship. As an additional incentive, they should also be given priority in the COVID-19 vaccination queue.\nA huge advantage in drawing from the medical student population is that they already have undergone the training needed to work with patients and administer intramuscular injections like most vaccines are. Hence, extensive training will not be required, However, it would be useful if they undergo a short course covering the vaccination programme, ethics ,and Standard Operating Procedures (SOPs) for vaccine administration at the participating institutions. Additionally, if they are allocated to the states where they are undergoing their education, cultural and language barriers should not be an issue.\nTo ensure a sustainable vaccine program against COVID-19 and strengthen other vaccination programs, frontline workers such as ASHA and ANM workers could also be trained/re-trained to administer this vaccine as a part of their training program.\nThis staffing structure could be a win-win for all the stakeholders \" the government by enabling much needed continuity in the backlog of routine non-COVID healthcare activities without hampering the vaccination campaign; Medical students by providing valuable field experience as part of a critical national mission, academic credits and priority in vaccination and the general population by an acceleration of the COVID-19 vaccination campaign.\nOf course, the success of such a strategy will depend heavily on the availability of a vaccine proven effective during the clinical trials, and made in enough doses to meet India's needs. Meanwhile, efforts are made to scale up >vaccine production and logistics to ensure a hassle-free >supply and delivery chain for various vaccines that will be coming into the market. While vaccine availability, production and delivery are being worked, we believe it is equally critical to focus on procuring adequate human resources. The government and academic institutions should start planning on having the required personnel trained for vaccine administration and ready to mobilise as and when the vaccine becomes available.\nThe authors are participants in Takshashila Institution's GCPP Health and Life Science programme", "pred_label": "__label__POS", "pred_score_pos": 0.5622166395187378}
{"content": "Silymarin is a milk thistle extract that nutritionally supports liver function. This highly active botanical protects the liver from free radical damage, supports glutathione concentrations and promotes superoxide dismutase activity. Milk thistle extract also stimulates protein synthesis in hepatic cells.\nSuggested Use As a dietary supplement take 1 to 4 capsules per day, in divided doses, between meals - Or as directed by your healthcare professional.", "pred_label": "__label__POS", "pred_score_pos": 0.9987865686416626}
{"content": "Objective:\nTo evaluate the significance of positive surgical margins after vertical hemilaryngectomy for squamous cell carcinoma of the larynx.\nDesign:\nA retrospective review of patients undergoing hemilaryngectomy over a 20-year period.\nSetting:\nA major academic medical center.\nPatients:\nFifty-six consecutive patients who underwent hemilaryngectomy between 1970 and 1990. Seventeen patients were excluded because of insufficient data or because they received postoperative radiation therapy.\nResults:\nEleven (28%) of 39 patients had cancer involvement of at least one margin. Two (8%) of 28 patients with negative margins and six (55%) of 11 patients with positive margins had recurrence. This difference in tumor recurrence is statistically significant. The mean disease-free interval prior to recurrence was 25 months, with no significant difference between the two groups. The mean follow-up periods for patients with positive vs negative margins were not statistically significant. There were no significant differences in survival estimates between patients with positive margins and those with negative margins.\nConclusions:\nDespite a sevenfold increase in tumor recurrence rates for patients with positive margins after hemilaryngectomy, there was no adverse effect on overall survival when these patients were managed with close follow-up and salvage surgery with or without postoperative radiation therapy for tumor recurrence.(Arch Otolaryngol Head Neck Surg. 1995;121:172-175)\nWenig BL, Berry BW. Management of Patients With Positive Surgical Margins After Vertical Hemilaryngectomy. Arch Otolaryngol Head Neck Surg. 1995;121(2):172–175. doi:10.1001/archotol.1995.01890020034008\n© 2020\nCoronavirus Resource Center\nCustomize your JAMA Network experience by selecting one or more topics from the list below.\nCreate a personal account or sign in to:", "pred_label": "__label__POS", "pred_score_pos": 0.699080228805542}
{"content": "Your VPN Won’t Cut it Anymore\nAt the beginning of 2020, organizations scrambled to provide employees with the means to work remotely. As we continue into a remote-first world, organizations need to enable people to work from anywhere, with the same security and productivity as their HQ.\nThe only problem: VPN and SD-WAN-based networks weren’t designed for this new normal. Employees are unable to access the resources they need to perform their job, responsiveness of enterprise applications are significantly slower, and IT is overwhelmed with the sheer volume of troubleshooting legacy network issues.\nThis eBook with NetFoundry will demonstrate how to rapidly overcome the security, performance, and network management constraints of legacy networks and VPNs as you transition toward a longer-term remote work strategy.", "pred_label": "__label__POS", "pred_score_pos": 0.8980852365493774}
{"content": "This is the finding from the recent fifth annual Circulars award, which recognizes businesses, governments and individuals that use innovation and disruptive technologies to reduce waste, emissions and the use of harmful materials.\nBelow is a selection of winner, shortlisted companies and their solutions.\nAward for Circular Economy Multinational: Schneider Electric (France) for integrating circular concepts throughout its business including prolonging product lifespan through leasing and pay-per-use; introducing take-back schemes into the supply chain and using recycled content and recyclable materials in their products.\n12% of the firm’s revenues now come from circular activities and, between 2018 and 2020, about 100,000 tonnes of primary resource consumption will be avoided.\nMiniwiz (Taiwan, China): For turning consumer waste into high-quality building materials.\nIts “Trashpresso” mobile upcycling plant enables recycling without shipping waste long distances.\nThe company has saved 17 million kilogrammes of CO2 in construction projects alone\nTianjin Citymine (China): For pioneering the concept of “urban mining” using mobile recycling stations at waste sites to produce a reverse-logistics system of urban waste\n“Moving to a circular economy delivers the disruptive change needed to secure a sustainable future, while enabling businesses to unlock innovation and growth. We are proud to recognize the individuals and organizations that are leading the circular movement, creating a thriving global economy.”", "pred_label": "__label__POS", "pred_score_pos": 0.8889620900154114}
{"content": "On one memorable episode of Friends, Ross is at the alter about to marry Emily, when he accidentally calls her 'Rachel.'\nCalling someone the wrong name is always a cringe-worthy moment (and doing it at the alter is even worse), but researchers found that this common mistake comes from nothing but love.\nCalling someone the wrong name is known as 'misnaming,' and in a study published last year in the journal Memory and Cognition, 1,700 people were asked whether they had ever been misnamed or misnamed others. \"We then asked what names were incorrectly used and the relationship between the people—or animals—involved,\" the authors explained. \"Our results confirmed that these errors are common and committed by people of all ages. (Moreover, misnaming does not appear to be an indicator of aging or of the cognitive decline typically associated with Alzheimer's disease.)\"\nThe person most common to commit a misnaming error? A parent, calling their children by the wrong names.\n\"Our results suggest it is not due to people looking alike, nor is it primarily driven by the similarity of the names involved (e.g. calling Mark \"Mike\"),\" the authors explain. \"Misnaming typically occurs within a social group: When family members misname other family members, the incorrect names they most often use are names of other people within the family. The same pattern is observed among friends: Friends usually misname each other using the incorrect name of another friend.\"\nBasically, we swap the names of people within the same social groups because we associate them with each other-- and care about them in the same way.\n\"...a mother likely associates her children with one another. When attempting to retrieve the name of her son, she is more likely to inadvertently select the name of her daughter than the name of a colleague due to the close connections between her children's names in her semantic network. In other words, your mom calls you by your sibling's name because she loves both of you, and associates you with one another.\"\nSo, next time you call your best friend--or even your boyfriend--by the wrong name, there's no need to stress: think of it as another language of love.", "pred_label": "__label__POS", "pred_score_pos": 0.574955940246582}
{"content": "Based on their excellent tumor-homing capacity, genetically engineered mesenchymal stem cells (MSCs) are under investigation as tumor-selective gene delivery vehicles. Transgenic expression of the sodium iodide symporter (NIS) in genetically engineered MSCs allows noninvasive tracking of MSC homing by imaging of functional NIS expression as well as therapeutic application of 131I. The use of tumor stroma-activated promoters can improve tumor-specific MSC-mediated transgene delivery. The essential role of transforming growth factor B1 (TGFB1) and the SMAD downstream target in the signaling between tumor and the surrounding stroma makes the biology of this pathway a potential option to better control NIS expression within the tumor milieu. Bone marrow-derived MSCs were stably transfected with a NIS-expressing plasmid driven by a synthetic SMAD-responsive promoter (SMAD-NIS-MSCs). Radioiodide uptake assays revealed a 4.9-fold increase in NIS-mediated perchlorate-sensitive iodide uptake in SMAD-NIS-MSCs after TGFB1 stimulation compared to unstimulated cells demonstrating the successful establishment of MSCs, which induce NIS expression in response to activation of TGFB1 signaling using a SMAD-responsive promoter. 123I-scintigraphy revealed significant tumor-specific radioiodide accumulation and thus NIS expression after systemic application of SMAD-NIS-MSCs into mice harboring subcutaneous tumors derived from the human hepatocellular carcinoma (HCC) cell line HuH7, which express TGFB1. 131I therapy in SMAD-NIS-MSCs-treated mice demonstrated a significant delay in tumor growth and prolonged survival. Making use of the tumoral TGFB1 signaling network in the context of MSC-mediated NIS gene delivery is a promising approach to foster tumor stroma-selectivity of NIS transgene expression and tailor NIS-based gene therapy to TGFB1-rich tumor environments.\nKeywords: TGFB signaling; gene therapy; hepatocellular carcinoma; mesenchymal stem cells; sodium iodide symporter.", "pred_label": "__label__POS", "pred_score_pos": 0.7442799806594849}
{"content": "On October 2, 2008, USCIS released fact sheets on the procedures for spouses and children of members of the U.S. Armed forces to apply for naturalization abroad. While spouses and children must still comply with the laws relating to eligibility for naturalization, they may now apply for it abroad. According to the new USCIS guidance, they must meet certain requirements to prove that they are stationed abroad:\n1. A spouse of a member of the U.S. Armed forces must have official military orders authorizing him or her to accompany their spouse abroad and must accompany their spouse abroad as provided in the orders.\n2. A minor child must also have official orders allowing him or her to accompany the parent abroad.\nAn applicant may consider time spent abroad on official orders as time meeting the physical presence requirements of being in the United States. A spouse who wishes to apply for naturalization in three years based on his or her marriage to an American citizen still has to prove marital union but USCIS understands that involuntary separations such as those due to deployment, do not prevent naturalization.\nCIS has provided a list of the required documents in their fact sheets available on their website.\nIt is not mandatory that a spouse or child apply abroad; is is an option they may choose. Unfortunately the USCIS guidance does not explain where the interview will take place. It is clear that the whole process may be done abroad, but the notice does not indicate where the applicant will have to go for an interview. I would assume it would be closest USCIS office abroad. This may or may not be so convenient for the applicant. The information provided also does not indicate what would happen to the application if the U.S. Armed force spouse/parent transferred to another country or left the military during this process. Presumably the application would be transferred to the USCIS district office closest to the applicant’s new residence.\nWhile this new process makes it easier for those residing abroad to apply for naturalization, I would not advise an applicant to go through this unless he or she was planning to be abroad for at least a year. I imagine there will be delays if the applicant transfers locations or returns to the U.S. and tries to tansfer the application back.", "pred_label": "__label__POS", "pred_score_pos": 0.5974382758140564}
{"content": "Every good author writes with a target audience in mind, but it is rare to find a book aimed simultaneously at strictly rationalist adherents to Ayn Rand’s political philosophy and also at believers in the Christian faith.\nNevertheless, in\nThe Soul of Atlas, Mark David Henderson has successfully authored a book that should be intellectually engaging and even satisfying to both parts of such a disparate audience.\nIndeed, Henderson has lived most of his life engaged in a conversation between the gospel-centered Christianity of his dad and the devout Objectivism of his stepfather.\nThis book is an invitation to join in this conversation and consider how these worldviews overlap or clash with the reader’s own perspective. Helping both groups toward engagement and understanding is the author’s explicit goal, and toward this end, Henderson articulates both views precisely and fairly.\nThe conversation begins by delineating the basic positions of Objectivism and Christianity by addressing four critical questions:\nWhat is the nature of reality? What is a person’s highest pursuit? What is wrong with the world? How does one fix it?\nThis provides the lay of the land for someone who might otherwise be a casual reader of the Bible or have encountered only one of Ayn Rand’s novels early in life.\nThe heart of the book devotes individual chapters to the essential topics of sex, money, capitalism, reason, meaning, selfishness, joy, and power. For each explosive subject, the Objectivist and Christian views are presented in an engaging way before concisely summarizing the main points of agreement and disagreement.\nThe astute reader might scan the helpful conclusion of each chapter first before returning to read the main text rich with quotations from Jesus Christ, characters of Ayn Rand’s books, and a variety of insightful authors.\nPerhaps the most valuable contribution of this book is that it avoids being a dry treatise on philosophy. Instead, riveting autobiographical events that Henderson unfolds in each chapter capture the reader.\nThe impact of philosophy on life is vividly demonstrated as the author struggles with radiation treatments for cancer as a sixteen-year-old. Moreover, he personally lives out the drama of his parents’ separation which echoes Dagny Taggart leaving Hank Rearden for John Galt in\nAtlas Shrugged. The agonizing questions about sex, identity, and meaning are vividly portrayed through Henderson’s college years.\nFor the author, this conversation is not reduced to theoretical banter; he has personally experienced the impact of these philosophical ideas in his life.\nChapter 11, “Who is John Galt? Really,” is worth the price of the entire book. Henderson deftly highlights the remarkable overlap between Ayn Rand’s hero, John Galt, and Jesus Christ.\nBoth were born in insubstantial towns and embarked on a mission to right the world. Both attracted many followers but were revealed clearly only to a small group in a remote place. Both persuaded people individually with patience, passion, and perseverance. Both articulated wisdom that resonated with a certain type of person prepared to hear it. Both were rejected, treated as common criminals, and were complicit in their own torture.\nBoth were prepared to die and yet prepared a paradise for a select few who recognized and accepted them.\nThese clear parallels force the reader to wrestle with the reality that Rand’s portrayal of the ideal man based solely on reason bears an uncanny resemblance to Jesus Christ.\nFor Christians, this provides helpful insights into why Objectivism has held such a deep attraction to so many intelligent and productive people.\nFor Randians, this provides an opportunity to reconsider the historical claims of Jesus Christ and to recognize the significant overlap in areas devoted to individual choice, free market exchange, and limited government.\nI highly recommend that you read this book whether you are a committed atheist, devout Christian, or anyone looking for an engaging introduction to two of the most profound influences of American ideology over the last century.\nLeave your comments here.", "pred_label": "__label__POS", "pred_score_pos": 0.5362763404846191}
{"content": "You were the only two ever to know true paradise. What was it like to wake every morning with no fear at all, to go throughout your day with only joy, wonder, beauty, pleasure in your work? What was it like to know your man only in harmony, as your beloved, your best friend?\nTill that day things were perfect. What was it like when you made that choice and everything changed in a single instant?\nI can imagine the fear, rushing over you in suffocating heaviness, narrowing your vision, crushing you to the ground. You suddenly knew pain, and everything must have become a threat. You suddenly knew you had to protect yourself. You had to hide.\nWe’ve been scared ever since. Scared is our M.O. Scared is where we live, what forms our thoughts, what drives us. Maybe we’re all scared of different things, and maybe we pretend otherwise, but ultimately we’re all just afraid, hiding in the garden that is no longer paradise.\nWe forget that everyone else is operating scared, too. I wonder how it would change our interactions to know this?\nScared wants you to think I’m fine. Scared wants control. Scared wants comfort and peace. Scared wants to hide.\nScared wants big answers to terrifying questions. Scared wants to stop hurting, stop losing.\nWe don’t have the answers to fear, and so fear grows.\nBut this is what He says: Perfect love casts out fear. Perfect love sits with an enemy and listens. It weeps with the anguish of others. It challenges selfishness and oppression. It washes feet, no matter how deserving. It touches disease and sits with death. And always, always, it points up to a holy God, the only one who truly knows how our fear has shaped us and how to set us free.\nOver and over He tells us, “Do not fear.” He never apologizes for being scary, or confusing, or seemingly absent, or too holy for us. He just says, “Don’t be afraid. You can trust Me.”\nYou can trust Me. love. It is utterly for me. It heals. While I journey in the pain, in the dark, in the confusion, perfect love is there, with me, and when I know it fully I will no longer be afraid. I will trust, even while hurting, even while blind, even while overwhelmed.\nI am not big enough for all the scary. Not strong enough, or wise enough, or anything enough. But He is. He promises His love is worthy of our trust.\nWhat are you scared of today? What is love asking you to do?", "pred_label": "__label__POS", "pred_score_pos": 0.5849749445915222}
{"content": "Counties need to be able to prepare for, respond to and recover from disasters in a timely fashion, and as part of this preparation, they need to ensure that critical infrastructure, such as energy, water, communications and transportation, remain operational, or that service can be quickly returned to normal following a disaster.", "pred_label": "__label__POS", "pred_score_pos": 0.9987586736679077}
{"content": "Delayed metabolic and thermogenic response to a mixed meal in normoglycemic European women with previous gestational diabetes. Kousta E., Parker KH., Lawrence NJ., Penny A., Millauer BA., Anyaoku V., Mulnier H., Forster DC., MacDonald IA., Robinson S., McCarthy MI., Johnston DG.\nWe assessed postprandial thermogenesis (PPT) for 3 h following a mixed meal in 29 normoglycemic European women with previous gestational diabetes (GDM), compared with 37 control women. Given the potential role of catecholamines and insulin in the regulation of PPT, we assessed insulin and catecholamine responses to the meal. There was no significant difference between the two groups in resting energy expenditure, PPT (although lower in the GDM group), or catecholamine levels. However, we observed a difference in the shape of the PPT curve between groups, and by applying a mathematical model, there was a consistent delay in PPT, insulin, and noradrenaline responses to the meal in the GDM group (T: fitted time constant, geometric mean (95% confidence interval), T(PPT) 58 (47-72) vs. 42 (37-48) min, P = 0.006; T(ins) 32 (28-37) vs. 22 (19-27) min, P = 0.002; T(NA) 30 (23-38) vs. 18 (14-23) min, P = 0.01, respectively). Fidgeting activity during the study was assessed by a novel technique and was lower in the GDM group, resting [427 (381-477) vs. 511 (466-560) kJ/min, P = 0.02] but not postprandially. These delayed PPT, insulin, and noradrenaline responses to the meal in post-GDM women represent early metabolic changes. The decrease in fidgeting activity while resting, observed in the post-GDM group, may have physiological significance for energy balance.", "pred_label": "__label__POS", "pred_score_pos": 0.99073725938797}
{"content": "The science we conduct often reflects the society we live in. One phenomenon of current society is the rise of the reality television show. Participants are promised instant media fame without having to struggle through acting school. I worry that this has rubbed off on some of the studies we now conduct. Sir Richard Doll […]", "pred_label": "__label__POS", "pred_score_pos": 0.5645135641098022}
{"content": "From mowing grass and cleaning your carpet to replacing a leaky faucet, maintaining your home is overwhelming. While stressful at times, cleaning, maintenance, and repairs are imperative parts of home ownership. Not only will these updates and improvements protect your home's function and appeal, but they are also necessary for upholding the value of your house. Unfortunately, you may not be placing enough importance on your home's windows. Although thousands are available on the market, many glass cleaners contain harmful ingredients that can affect your health and the environment.\nCommonly found in most popular glass cleaners, ammonia effectively removes dirt and residue from glass surfaces. However, the ingredient can be surprisingly toxic. Using this guide, you will understand the dangers of ammonia and learn how to clean your windows and glass surfaces in a safe, natural manner.\nAnnoyed with Ammonia\nWith spring quickly approaching, you may be planning on a thorough washing of your windows, but skipping sprays that contain ammonia is smart. While surprising to hear, exposure to ammonia creates the following health issues:\nIrritated Skin Irritated, Red, Swollen Eyes Coughing Wheezing Breathing Difficulty Increased Symptoms in Asthma Patients\nMany homeowners use an ammonia-based glass cleaner on their windows and bleach on their home's exterior. This not only doubles the toxicity, but also directly affects surrounding landscaping and wildlife. In addition, ammonia and chlorinated bleach will pollute the air.\nTo protect your health and the environment, consider washing windows and other glass surfaces with simple techniques and natural ingredients.\nSqueegee\nIf you wash your windows yearly, cleaning sprays and solutions may not be necessary. Purchase a squeegee tool on a long handle to remove excess water and dirt from your windows without ammonia or other glass cleaners.\nUse your garden tool to rinse off a window. Before the water dries, move the squeegee blade vertically across the glass. Wipe off the squeegee blade to remove excess liquid and dirt. Then, move the squeegee horizontally across the window.\nRepeat the process for each window to remove dirt and residue without any toxic chemicals.\nBaking Soda\nYou most likely have a box or two of baking soda in your pantry, but you may not be familiar with its many uses. The sodium bicarbonate creates a bubbling, fizzing sensation when it comes in contact with moisture. This carbonation effectively removes dirt and residue from surfaces including glass windows.\nIn a spray bottle, combine the following ingredients:\n3 cups of water ½ cup of baking soda\nShake the bottle to ensure the baking soda dissolves completely into the water. Then, douse on your window. In most cases, your garden hose will completely rinse off the dirt and leftover baking soda solution. If not, use your squeegee tool to remove the residue.\nThis baking soda solution quickly cleans your windows, but it is also effective for window frames, shutters, and vinyl siding.\nVinegar\nDue to the outdoor elements and changing weather conditions, you may need a stronger glass cleaner for your windows. Fortunately, vinegar is strong, effective, but safe and gentle for your health and the environment. Vinegar also cleans and shines without creating streaks across your glass surfaces. Plus, its acidic properties naturally kill mold, mildew, and bacteria.\nIn an outdoor pump sprayer, combine the following ingredients:\n2 gallons of water 2 gallons of white vinegar ½ cup of lemon juice\nSpray on your windows and other glass surfaces. Allow to soak for 15 minutes before rinsing off with your garden hose. For added shine, spray the vinegar solution and wash windows with balled-up newspapers.\nCleaning and maintaining your home without harmful ingredients protects your health and the environment. Using this guide, your windows and glass surfaces will be clean, appealing, and eco-friendly. For even better results, consider contacting a professional window washing company like Clear View Inc.\nShare", "pred_label": "__label__POS", "pred_score_pos": 0.5783175230026245}
{"content": "Journal of Cognitive Neuroscience\nVisual search is often guided by top–down attentional templates that specify target-defining features. But search can also occur at the level of object categories. We measured the N2pc component, a marker of attentional target selection, in two visual search experiments where targets were defined either categorically (e.g., any letter) or at the item level (e.g., the letter C) by a prime stimulus. In both experiments, an N2pc was elicited during category search, in both familiar and novel contexts (Experiment 1) and with symbolic primes (Experiment 2), indicating that, even when targets are only defined at the category level, they are selected at early sensory-perceptual stages. However, the N2pc emerged earlier and was larger during item-based search compared with category-based search, demonstrating the superiority of attentional guidance by item-specific templates. We discuss the implications of these findings for attentional control and category learning.", "pred_label": "__label__POS", "pred_score_pos": 0.9987536072731018}
{"content": "This website provides a broad range of resources relating to the effective use of emergency manuals to enhance patient safety. Emergency manuals are increasingly being used in a wide range of clinical settings, along with other forms of ‘cognitive aid’ such as checklists.\nThese tools aim to help clinicians and teams consistently deliver best practice, provide a framework for teams to train for, manage and debrief critical events and embed the actual use of emergency manuals into clinical practice.\nThe focus of the resources on this website is on perioperative crises, but the principles demonstrated by many of these resources are applicable to a wide range of clinical settings.", "pred_label": "__label__POS", "pred_score_pos": 0.9827245473861694}
{"content": "Abstract\nPancreatic ductal adenocarcinoma (PDAC) patients have poor prognosis and poor response to treatment. This is largely due to PDAC being associated with a dense and active stroma and tumor fibrosis (desmoplasia). Desmoplasia is characterized by excessive degradation and formation of the extracellular matrix (ECM) generating collagen fragments that are released into circulation. We evaluated the association of specific collagen fragments measured in pre-treatment serum with outcome in patients with PDAC. Matrix metalloprotease (MMP)-degraded type I collagen (C1M), type III collagen (C3M), type IV collagen (C4M) and a pro-peptide of type III collagen (PRO-C3) were measured by ELISA in pre-treatment serum from a randomized phase 3 clinical trial of patients with stage III/IV PDAC treated with 5-fluorouracil based therapy (n = 176). The collagen fragments were evaluated for their correlation (r, Spearman) with serum CA19-9 and for their association with overall survival (OS) based on Cox-regression analyses. In this phase 3 PDAC trial, pre-treatment serum collagen fragment levels were above the reference range for 67%-98% of patients, with median values in PDAC approximately two-fold higher than reference levels. Collagen fragment levels did not correlate with CA19-9 (r = 0.049–0.141, p = ns). On a continuous basis, higher levels of all collagen fragments were associated with significantly shorter OS. When evaluating degradation (C3M) and formation (PRO-C3) of type III collagen further, higher PRO-C3 was associated with poor OS (>25\nth percentile cut-point, HR = 2.01, 95%CI = 1.33–3.05) and higher C3M/PRO-C3 ratio was associated with improved OS (>25 th percentile cut-point, HR = 0.53, 95%CI = 0.34–0.80). When adjusting for CA19–9 and clinical covariates, PRO-C3 remained significant (HR = 1.65, 95%CI = 1.09–2.48). In conclusion, collagen remodeling quantified in pre-treatment serum as a surrogate measure of desmoplasia was significantly associated with OS in a phase 3 clinical PDAC trial, supporting the link between desmoplasia, tumorigenesis, and response to treatment. If validated, these biomarkers may have prognostic and/or predictive potential in future PDAC trials. All Science Journal Classification (ASJC) codes General", "pred_label": "__label__POS", "pred_score_pos": 0.5894489288330078}
{"content": "Phishing is a scam through which one receives a fraudulent email programmed to steal one’s identity or personal information, such as credit card numbers, SSN, bank account numbers, debit card PINs, and passwords. The email typically states that your account has been compromised or accessed, or that one of your accounts was charged incorrectly. The email will instruct you to click a link in the email or reply with your bank account number and password to confirm your identity or verify your account. The email oftentimes threatens to disable your account if you don’t reply. Don’t believe it!\nTrue and legitimate companies should never ask for your account number or password via email correspondence. If you receive a phishing email, consider one or all of the below listed recommendations:\nDo not click any links contained in the email as they typically contain a virus that can harm your computer. Even if links in the email indicate the name of the company, don’t trust them. The links may redirect you to a fraudulent website that appears to be legitimate. Don’t reply to the email itself. Instead, you should forward the email to the Federal Trade Commission at spam@uce.gov. If you believe that the email is valid you may contact the company using the phone numbers listed on your statements, on the company’s website, or in the phone book. Tell the customer service agent about the email and ask if your account has been compromised. If you clicked on any links in the phishing email or replied with the requested personal information, contact the company directly to let them know about the email and ask to have fraud alerts placed on your accounts, have new credit cards issued, or set new passwords. Vishing\nSimilar to phishing, vishing scammers also seek to get you to provide your personal information. However, vishing scams use the phone to make their requests, instead of email. You may be directed to call a phone number to verify an account or to reactivate a debit or credit card. If you have received one of these calls, report it to the Internet Crime Complaint Center.", "pred_label": "__label__POS", "pred_score_pos": 0.8206380009651184}
{"content": "Many businesses in the past few years have transitioned to think mobile first, quickly realising the dramatic shift in consumers’ digital media consumption. As business strategies realign, the drive for mobile location data for campaign targeting and the creation of personalised and relevant stories has become evermore prevalent.\nMobile devices teleport us; they transport users from destination to destination throughout their entire day, playing the roles of both communication tools and utility devices. Each visit, frequent or not, builds a picture of a consumer’s individuality, enabling advertisers to enhance their marketing objectives through creative outputs.\nLocation derived data-driven advertising practices have been used for some time now, but have perhaps been overshadowed by an older methodology — geo-fence-based targeting. Yes, geo-fencing can extrapolate powerful results, but location intelligence provides much deeper detail and insight.", "pred_label": "__label__POS", "pred_score_pos": 0.5952582359313965}
{"content": "Venues all across the country are becoming proactive in preparing for a potential Active Shooter threat. When an incident involving an active shooter occurs, time is crucial. Department of Homeland Security research reveals that 70% of active shooter incidents end in 5 minutes or less. In contrast, the average response time for law enforcement is 10 minutes. It only makes sense for us to find ways to improve our reaction time. How you respond, will determine if you survive.\nOur Nightlife Active Shooter & Terrorism Awareness Training Course is an effective risk mitigation model tailored to the nightlife environment. We designed this training specifically for nightclubs, bars, entertainment venues, and the alcohol service industry. While training with multiple courses across the nation, we discovered the lack of training for nightlife venues. Our team has developed a training that adapts to YOUR environment.\n*Contact Us for private venue training, or register below for our public courses*", "pred_label": "__label__POS", "pred_score_pos": 0.9872981905937195}
{"content": "A CRISPR-Cas9-based reporter system for single-cell detection of extracellular vesicle-mediated functional transfer of RNA. de Jong OG., Murphy DE., Mäger I., Willms E., Garcia-Guerra A., Gitz-Francois JJ., Lefferts J., Gupta D., Steenbeek SC., van Rheenen J., El Andaloussi S., Schiffelers RM., Wood MJA., Vader P.\nExtracellular vesicles (EVs) form an endogenous transport system for intercellular transfer of biological cargo, including RNA, that plays a pivotal role in physiological and pathological processes. Unfortunately, whereas biological effects of EV-mediated RNA transfer are abundantly studied, regulatory pathways and mechanisms remain poorly defined due to a lack of suitable readout systems. Here, we describe a highly-sensitive CRISPR-Cas9-based reporter system that allows direct functional study of EV-mediated transfer of small non-coding RNA molecules at single-cell resolution. Using this CRISPR operated stoplight system for functional intercellular RNA exchange (CROSS-FIRE) we uncover various genes involved in EV subtype biogenesis that play a regulatory role in RNA transfer. Moreover we identify multiple genes involved in endocytosis and intracellular membrane trafficking that strongly regulate EV-mediated functional RNA delivery. Altogether, this approach allows the elucidation of regulatory mechanisms in EV-mediated RNA transfer at the level of EV biogenesis, endocytosis, intracellular trafficking, and RNA delivery.", "pred_label": "__label__POS", "pred_score_pos": 0.9403219223022461}
{"content": "Mylea Charvat, Ph.D. Mylea Charvat, Ph.D., is a clinical psychologist, translational neuroscientist, and the CEO and founder of the digital cognitive assessment company, Savonix. She specializes in working with and leading dynamic healthcare organizations looking to expand the access to and affordability of healthcare using digital tools.\nDr. Charvat founded Savonix to address a critical challenge in the healthcare world: how do we assess the mental health, specifically the cognitive and emotional function, of patients on a large scale despite limited dollars and insufficient numbers of trained specialists? Savonix has developed mobile tools that utilize critical cognitive data to better understand patients’ health, identify those at risk and improve outcomes at the individual and systems level in healthcare.\nA trained clinical psychologist with a neuro specialty, Dr. Charvat is a recognized thought leader in her field. She completed her fellowship in clinical neuroscience at Stanford School of Medicine and has been a lecturer at Stanford, the University of San Francisco and San Francisco State University. She has authored several peer-reviewed articles published in well-respected mental health and neuro-imaging journals. She is a frequent guest author for the Huffington Post, has written for Tech Crunch and has appeared as a subject matter expert at multiple conference and events including with The Atlantic Council, Hyper Wellbeing, and The CA State Forensic Medical Association.\nDr. Charvat is committed to advancing the integration of behavioral health data into mainstream health and wellness. The inspiration for Savonix came when Mylea’s husband was severely injured in a tragic accident and she experienced first-hand the difficulty in attaining the vital health data her husband needed to achieve recovery including cognitive screening", "pred_label": "__label__POS", "pred_score_pos": 0.7464563250541687}
{"content": "A hand-picked group of international students spent a gruelling weekend at a space boot camp in Crans-Montana, in southwestern Switzerland. Though firmly on planet Earth, the aspiring astronauts were preparing for a space mission.\nThe camp, set up on frozen Lake Moubra in canton Valais, is part of the Asclepios project, a space mission simulating a mission on another celestial body. The project is led by Space@yourService, a student association from the Federal Institute of Technology in Lausanne (EPFL). During the camp, researchers collected psychological and physical data to better understand how astronauts react in difficult and unfamiliar situations.\nParticipants from several countries were chosen from among 200 candidates, mimicking the selection process of the European Space Agency (ESA). The young team called in specialists to help, including EPFL professor and former Swiss astronaut Claude Nicollier, French polar explorer Alban Michon and experts from the European Space Agency (ESA).\nThe simulated mission Asclepios will take place in April at an as-yet undisclosed location in the Jura mountains in Switzerland. Six astronauts will spend seven days isolated in a module that replicates the exact conditions of a space habitat. Everyday life inside the module will be based on real-life NASA and ESA missions.\nThis article was automatically imported from our old content management system. If you see any display errors, please let us know: community-feedback@swissinfo.ch", "pred_label": "__label__POS", "pred_score_pos": 0.5391576290130615}
{"content": "Example - Marketability\nDiscounts and Control Premium\nEstate of William J. Desmond,\nv. IRS\n[full\ntext] [excerpted]\nT.C. Memo 1999-76 (U.S. Tax Court 1999).\nWilliam Desmond died holding 136,000\nshares (81.93%) of Deft Corporation, a small closely\nheld company that manufactures industrial paint\nfor military and commercial uses. The IRS claimed\nthat Desmond's estate tax return underreported\nthe value of Desmond's interest in Deft and accordingly\ndetermined a deficiency and assessed a large penalty.\nThe key issue before the court, therefore, was\nto determine the fair market value of Desmond's\ninterest in Deft.\nBoth Desmond's estate and the IRS\nsubmitted expert valuation reports to the court.\nThe estate valued Deft using three methods: Asset\nmethod, income method, and market method. It averaged\nthe results obtained under the three methods and\nthen applied a 25% lack of marketability discount.\nTHe IRS's expert did not address the fundamental\n(\"unadjusted\") value of the company,\nfocusing solely on the appropriate lack of marketability\ndiscount instead.\nThe court adopted Desmond's conclusion under\nthe income and market methods, and rejected the\nasset method results as \"vague and generally\nunhelpful.\" Under the income method, Desmond's\nexperts projected the future cash flows of Deft\nand then discounted these projections using a\ndiscount rate determined by the Capital Asset\nPricing Model (CAPM), applying a beta derived\nfrom the betas of eight similar publicly-traded\npaint finishing companies. The court averaged\nthe valuation obtained under both methods. To\nthis amount, the court applied discounts for lack\nof marketability and pending environmental liabilities\nDeft was facing.\nMarketability discount. On the\nquestion of marketability discounts, the court\nconcluded:\nDeft's potential environmental liability affected\nthe value of the company's stock\nThe environmental risk properly resulted in\ndiscounting under the income method, but not\nthe market method.\nThe\nbetas of 8 comparable companies\nused to determine the discount rate under the\nincome method were not shown to be \"higher\nthan normal due to potential environmental liabilities\nfaced by these companies.\" The price-earnings ratio for two similar companies\n\"already include the potential environmental\nproblems faced by the similar companies\"\nand thus the price-earnings ratio used under\nthe market method \"took into account the\npotential environmental liabilities of the comparable\ncompanies.\"\nThe court found the following factors \"favor\na high lack of marketability discount\":\nThere was no public market for Deft's stock\nDeft's profit margins were below the industry\naverage\nAll stock in Deft was subject to a restrictive\nshare agreement which provided that a shareholder\ncould transfer his or her stock to a non shareholder\nonly after the shareholder offered the shares\nto the remaining shareholders\nGiven the size and low profitability of Deft,\na public offering of the stock was unlikely\nin the future\nThe size of the interest is so large that\nit may be hard to find potential buyers in the\nfuture who could finance such a purchase\nDeft has large potential environmental liabilities.\nThe court concluded, without explanation, that\na 30% lack of marketability discount was appropriate\nfor the Deft stock. Of this 30% discount, 10%\nwas attributed to Deft's potential environmental\nliabilities - again, without explanation. The\ncourt applied the 30% discount to the value determined\nunder the income method. The court applied only\na 20% discount to the value determined under the\nmarket method.\nControl premium. The court then\nturned to whether the 82% interest held by Desmond\nwarranted a control premium. As the court explained,\na \"control premium may be necessary when\nvaluing an interest which gives its holder unilateral\npower to direct corporate action, select management,\ndecide the amount of distributions, rearrange\nthe corporation's capital structure, and decide\nwhether to liquidate, merge or sell assets.\"\nThe court concluded that whether a control premium\nis appropriate depends on the valuation method.\nThe income method, the court stated, \"assumed\nthe continuation of Deft's present policies and\ndid not account for a change in control.\"\nIt thus produced an unadjusted value based on\na minority interest, making it proper to apply\na control premium. The market method, based on\ncomparisons with publicly traded stocks, also\nproduces an unadjusted value based on a minority\ninterest, making a control premium proper.\nAccepting the estate's expert's 25% control premium,\nthe court applied it to the the market method, but\nnot market method since the expert had already .\nWe find HML's determination reasonable, and we conclude\nthat a control premium of 25 percent is appropriate.\nWe shall apply this premium to the unadjusted value\nwe determined under the income method.\nCourt decision:\nIncome method\nMarket method\nUnadjusted Value\n(based on expert's report)\n$ 8,109,000\n$ 10,410,000\nLess Marketability Discount:\n20%\n(1,621,800)\n20%\n(2,082,000)\n10%\n(810,900)\n0%\nAdd Control Premium (already\nincluded in expert's report for market method)\n25%\n2,027,250\n0%\nFair Market Value of\n100% interest\n7,703,550\n8,328,000\n81.93%\n6,311,519\n81.93%\n6,823,130\n50%\n3,155,759\n50%\n3,411,565\nFMV Decedent's\nInterest\n6,567,324\nSome questions:\nWhy isn't the potential environmental risk\nalready impounded in the discount rate implicit\nin both the betas of comparable companies and\ntheir price-earnings ratios?\nCan you explain why a company's beta does\nnot reflect environmental risks, but its market\nvaluation would?\nCan there be individual shareholders risks\nthat are beyond the general company risks, reflected\nin comparable P/E ratios and CAPM discounts?\nWhy is a buyer willing to pay more, on a relative\nbasis, for an 82% interest than a an 8.2% interest\nin the same company?\nIs there any reason to believe that new management\nis more effective in increasing corporate returns\nthan existing management?\nShould the market value of an asset (here\na company) depend on the value placed on it\nby a buyer, because of changes that will happen\nin the future?", "pred_label": "__label__POS", "pred_score_pos": 0.7969558238983154}
{"content": "2020 has been a year like no other, but you don’t need me to tell you that. We’ve all been living it! A global pandemic, mounting social justice issues, civil unrest, a polarizing election. This year has been A LOT!\nOver the last 8 months, I have surfed the waves of anxiety and I’m pretty confident I’m not the only one. At times, it’s been easy to let the circumstances of this year overwhelm me. And now, as we near the holiday season, with COVID cases increasing every day, I feel the waves of anxiety starting to churn again. I have been here before, most notably back in March.\nI flipped through my journal to something I wrote on March 17, 2020. It was written just a few days after everything began to shut down. Anxiety was starting to rear its ugly head. I felt it mentally and physically. In that moment, I turned to the coping mechanisms that work for me like yoga, grounding techniques like boxed breathing and the 5-4-3-2-1 exercise, limiting my social media and news intake, and listening to music. Most importantly, as a follower of Jesus, I turned to the Bible. I started to identify verses that were encouraging and filled with truth to help center my thoughts and shift my focus. In some of my most anxious moments, meditating on the truth of these verses has helped me to refocus. Today, I want to share a few of my favorites with you. If you’re like me and battling some anxiety, I hope you find these verses encouraging!\nFeeling anxious? What coping mechanisms do you turn to manage anxiety?", "pred_label": "__label__POS", "pred_score_pos": 0.8267611265182495}
{"content": "Researchers expect under-reaction in climate policy. However, this might differ depending on the access of different interest groups to a political system. To explore the relationship between entrenched patterns of domestic politics and proportionality of climate policy, we compare two renewables policies which financially support new renewable electricity in the UK. Drawing on the literature on policy styles and related opportunity structures, this article shows that UK political parties have responded to growing public concern and NGO pressure by, at times, trying to out-green one another to win votes. However, powerful industry actors have been influential in shaping UK renewables policies, in particular when political competition about the individual policies has been low. The findings suggest that an over-reaction in terms of exceeding the marginal costs of renewable electricity production is equally likely under conditions of high or low political competition.", "pred_label": "__label__POS", "pred_score_pos": 0.6824420690536499}
{"content": "IGF Bulletin Saturday, 24 October 2020 16th Annual General Meeting of the Intergovernmental Forum on Mining, Minerals, Metals and Sustainable Development (IGF) 20-22 October 2020 | Virtual\nThe 16th Annual General Meeting (AGM) of the Intergovernmental Forum on Mining, Minerals, Metals and Sustainable Development (IGF) focused on the theme of “Mining and COVID-19: From Crisis to Sustainability.”\nThe meeting sought to bring diverse perspectives on how the mining sector is navigating the COVID-19 crisis, and how governments are responding. Participants discussed the impacts of COVID-19 on various aspects of mining, including employment, community resilience, gender equality, artisanal and small-scale mining (ASM), climate action, resource taxation, and technological innovation.\nKey issues addressed included loss of employment in mining communities due to border closures and decreased worker mobility, health and safety concerns, and increases in poverty and food insecurity. Speakers cited, for example, the International Labour Organization’s (ILO) estimate that the number of working hours lost to COVID-19 is equal to the loss of 500 million full-time mining jobs. Nevertheless, many speakers also noted the opportunity to transition to a more sustainable mining sector and the possibility of achieving the Sustainable Development Goals (SDGs) through such efforts. They expressed optimism for the sector’s recovery in 2021.\nParticipants discussed a number of concerns during the meeting related to:\nmaintaining mining companies’ social license to operate, through greater accountability to local communities, trust building, and developing a shared vision whereby the profits of mining adequately benefit source countries; improving domestic revenue collection from the mining sector through tax reforms, including measures to reduce tax base erosion and profit shifting, and greater transparency in minerals pricing; using digital technology to replace physical labor in mining, and training workers with the relevant skills in robotics, automation, and remote equipment operation; developing policies for mine closure, including financial assurance to support closure and rehabilitation of old mines before land is returned to communities for other uses; greening the mineral supply chain by reducing carbon emissions in mining and transport of minerals; and adopting tools and approaches for gender impact assessments, to better understand the potential impact of mining projects in exacerbating, or reducing, existing gender inequality patterns, as well as impacts on ethnic minorities and indigenous peoples’ territories.\nA key feature of AGMs has been the review and sharing of guidance documents developed by the IGF Secretariat and its partners. Earlier this year, participants were presented with IGF guidance on improving legal frameworks for environmental and social impact assessment (ESIA) and management, which summarizes international best practices in this area. Another session presented upcoming IGF guidance for governments on environmental management and mining governance, which was published as a draft for further consultation.\nThe AGM also heard about measures to implement the new Global Industry Standard on Tailings Management, developed after the tragic collapse of the Brumadinho tailings dam in Brazil in January 2019, which killed 270 people. The Global Standard was published in August 2020, following a consultation process that took place in seven languages, led by the UN Environment Programme (UNEP), the Church of England’s Pensions Board, and the Principles for Responsible Investment (PRI).\nThe AGM took place from 20-22 October 2020 in a virtual format, due to the global spread of COVID-19. More than 1800 participants from 110 countries registered for the three-day event, with two sessions running in parallel, much of the time. One-third of participants were from government ministries and agencies, including some ministers, deputy ministers, and other high-level officials.\nIn meeting polls, many welcomed the virtual format, noting it enabled many more participants to take part in the deliberations. Some participants also used the online chat space to engage in group discussions during the presentations, a move that the organizers welcomed as promoting engagement with the topics at hand. During the closing session, Greg Radford, Director, IGF Secretariat, proposed future AGMs continue to find a way to incorporate online participation. The 17th AGM will take place in the autumn of 2021.\nThis report provides a brief history of the IGF and a summary of discussions of the three-day AGM.\nA Brief History of the IGF\nThe IGF serves as a global platform for dialogue among member governments, mining companies and industry associations. It is an outcome of the 2002 World Summit on Sustainable Development (WSSD), which took place in Johannesburg, South Africa. The WSSD encouraged governments, civil society and private sector actors to enter into voluntary partnerships focused on sustainable development objectives. Its Johannesburg Plan of Implementation specifically called for efforts to address the environmental, economic, health and social impacts and benefits of mining, minerals and metals throughout their life cycle, including worker health and safety issues, and to promote transparency and accountability for sustainable mining.\nFollowing the WSSD, the Governments of Canada and South Africa were instrumental in establishing the IGF. It was announced in February 2005 as a voluntary initiative for national governments interested in promoting good governance in the management of mineral resources. To date, the IGF has 76 government members.\nThe IGF’s work is largely framed by its flagship policy guidance and assessment tool, the Mining Policy Framework (MPF), which was first presented at the 19th session of the UN Commission on Sustainable Development in 2011. The MPF identifies best practices through six pillars of mining policy and law: the legal and policy environment; financial benefit optimization; socio-economic benefit optimization; environmental management; mine closure and post-mining transitions; and ASM.\nIn 2012, the UN Conference on Sustainable Development (UNCSD or Rio+20) convened to assess global sustainable development policy. Its outcome document, “The Future We Want,” further boosted the IGF’s work. Besides calling on the international community to negotiate a set of SDGs, the Rio+20 outcome urged governments and businesses to promote accountability and transparency in the mining sector, as well as improve existing mechanisms to prevent illicit financial flows from mining activities.\nIn October 2015, the IGF Secretariat moved from its home at the Canadian Department of Foreign Affairs, Trade and Development to the International Institute for Sustainable Development.\nThe IGF AGMs first convened in 2005 with 25 member countries. They provide a forum in which members can engage with industry, civil society and each other on best practices, and exchange knowledge and ideas. Previous AGMs have discussed topics relevant to the MPF, including: fiscal and legislative frameworks for investment in the mining sector; revenue sharing; community engagement and benefits; the role of women in mining; and post-mining transitions, including mine closure and rehabilitation of mine sites. AGMs also present draft guidance on various aspects of sustainable mining, before public release. Most recently:\nin 2016, the 12th AGM provided an opportunity for IGF members to consider the SDGs’ relevance to the mining sector; in 2017, the 13th AGM produced IGF guidance for governments on managing ASM; in 2018, the 14th AGM discussed the impacts of increased global lithium demand on mining, and the contribution of ESIAs, tax reform, and community engagement in sustainable mining; and in 2019, the 15th AGM: focused on “mining in a changing climate,” discussing ways that companies are starting to reduce emissions from mining operations and adapting to changes in the environment, such as increased water scarcity and disaster risks; and reviewed draft guidance on ESIAs, prior to its subsequent release. Report of the Meeting Session 1: Welcome and High-level Remarks\nIsabelle Ramdoo, Deputy Director, IGF Secretariat, opened the IGF AGM on Tuesday on behalf Greg Radford, Director, IGF Secretariat. She provided an overview of the IGF’s role, noting it provides a platform for stakeholders to engage on ways to further the sustainable governance agenda. She said this year’s theme, “Mining and COVID-19: From Crisis to Sustainability,” aims to bring a diverse range of perspectives on how the mining sector is navigating the crisis and responses of governments.\nAïssatou Sophie Gladima, Minister of Mines and Geology, Senegal, outlined the difficulties COVID-19 has posed, including: decreased mobility of workers; health and safety issues; and efforts to avoid large-scale downsizing in the sector. Gladima said support thus far has included the fair distribution of benefits and bolstering government capacity to address these issues. She further stated that ensuring the welfare of the most vulnerable sectors of society, namely women and children, is key.\nNorbert Barthle, Parliamentary State Secretary to the Federal Minister for Economic Cooperation and Development, Germany, said the pandemic presents an opportunity to transition to a more sustainable global economy. German efforts to achieve this, he detailed, include addressing climate change and environmental degradation through transitioning to carbon-neutral energy and transport sectors, and ensuring responsible, sustainable supply chains. He cited steps to support these efforts, including: developing key points of a due diligence legislation in Germany; supporting EU-wide regulation on the issue; and supporting the G7 CONNEX Initiative to improve the quality of advisory support provided to low-income country governments in their negotiation of complex commercial contracts.\nLuis Miguel Incháustegui Zevallos, Minister of Energy and Mines, Peru, said that, following COVID-19, the Peruvian mining sector is expected to have one of the largest economic recoveries in 2021, with the creation of approximately 600,000 new jobs. He noted key areas of focus include improving the competitiveness of the sector, while preserving the health and welfare of those workers and communities impacted. Incháustegui said any activities undertaken in the mining sector must ensure the trust of and buy-in from local communities.\nDaniel Kaufmann, President Emeritus, Natural Resource Governance Institute (NRGI), outlined the most pressing global challenges, including: the COVID-19 pandemic; the global economic downturn; climate change; and increased natural resource demand. He suggested addressing these through: integrated resource plans that seek to avoid “silo” effects; investment plans that contribute to energy transitions; and better governance. He emphasized the need for a new shared vision for the mining industry, its stakeholders and its resources.\nThe IGF Secretariat then conducted a number of online polls, including opinion surveys, as well as general knowledge questions about the future of mining. The polls highlighted, for example, that World Bank figures indicate global demand for graphite, lithium and cobalt will rise by 500% by 2050.\nSession 2: The Future of Mining Employment and Skills\nAaron Cosbey, IGF Secretariat, introduced this session on Tuesday. Moderator Nicky Black, Director, Social and Economic Development, International Council on Mining and Metals (ICMM), drew attention to issues around how to recruit and train workers in the skills needed to work with new technologies, options that governments can take, and how non-governmental stakeholders can help. Black outlined ICMM’s “Skills for our Common Future” initiative that undertakes partnerships to accelerate and build skills in mining communities over a 15-year period.\nCasper Edmonds, Head of Unit, Extractives, Energy and Manufacturing, Sectoral Policies Department, ILO, underscored the number of working hours lost due to COVID-19 is equivalent to 500 million full-time jobs lost in the mining industry globally. To endure the current era of uncertainty, he asserted that skills and investing in them are critical, and the mining sector should adopt the concept of life-long learning.\nMusa Fazal, Group Director, Planning Group, SkillsFuture Singapore, outlined Singapore’s process for developing a sectoral skills strategy, stating it must: include a skills framework, including a transformation plan for the sector; leverage big data to identify emerging skills; and ensure a robust training sector. He said these are multi-stakeholder endeavours that must be constantly updated.\nJanne Kaiser-Tedesco, Advisor, Extractive Governance and Organizational Development, German Agency for International Cooperation, underscored that automation in the mining sector will likely translate to less employment for members of remote mining communities. She emphasized a role for mining companies and governments to promote local skills development and transfer, but said the majority of these have a limited impact. Factors for success, she stated, include demand-driven programmes and on-the-job training.\nQuestions posed by the audience addressed: how to integrate capacity building into tight construction or production processes or timelines; how ASM features in the future skills of mining; and the need to ensure a common understanding about expectations and accountability in public officials through capacity building.\nSession 3: Global Standards for Environmental and Tailings Management\nOn Tuesday, Greg Radford, Director, IGF Secretariat, presented a video introducing the Global Industry Standard on Tailings Management, which was developed through a process co-convened by UNEP, PRI and ICMM, following the collapse of a tailings dam in Brumadinho, Brazil, in January 2019, which killed 270 people. The Global Standard was launched in August 2020.\nModerator Jenifer Hill, IGF Secretariat, elaborated on the current development of the IGF’s next guidance for governments on environmental management and mining governance, which was published as a draft for consultation ahead of the event. She invited participants to contribute feedback on and suggestions for the guidance document.\nAidan Davy, Chief Operating Officer, ICMM, and John Howchin, Secretary-General, Council on Ethics, Swedish National Pension Funds, presented on the process toward implementation protocols, including an ICMM Tailings Management Good Practice Guide, and a Conformance Protocol that will map closely to Global Standard requirements.\nDavy explained that the Conformance Protocol will ensure integration of the Standard into ICMM’s assurance processes for members, and support self-assessments or independent third-party assessments of progress.\nHowchin welcomed the interest and support shown by bankers, investors and insurers. He called on everyone to seriously address the issue of tailings management, as the mining industry’s social license to operate has been questioned. He noted the process of developing the Standard was informed by a multi-stakeholder advisory group, and a thorough, seven-language process of public consultation was undertaken.\nDavy introduced the six topic areas in the Global Standard: affected communities; an integrated multi-disciplinary knowledge base; design, construction, operation and monitoring; management and governance; emergency response and long-term recovery; and public disclosure and access to information. He noted the Global Standard strengthens existing standards and includes new requirements for management oversight.\nHowchin recalled the Church of England Pensions Board’s role in launching its Mining and Tailings Dam Initiative. He said 726 mining companies were invited to disclose information about their tailings dams, and information on 1,000 tailings dams was publicly available through a partnership with UNEP.\nDavy outlined requirements for ICMM members to comply with the Global Industry Standard on Tailings Management within a three- to five-year period, with the shorter timeframe required for all facilities classified as having extreme or very high potential consequences of inaction.\nParticipants posed questions about disposal, upstream construction, entry points for adaptation to climate change, and the transparency challenge of changing “centuries-old corporate culture” at mining companies. Davy emphasized the application of climate knowledge is “hard-wired” into the Standard, especially regarding the requirement to maintain an integrated knowledge base. Howchin remarked tailings have been treated as an externality of mining, and the Brumadinho accident had led to greater recognition of the need for responsible tailings management.\nParticipants also inquired about how the proposed independent institute to oversee implementation of the Global Standard would be funded, and how current initiatives can influence the work of unlisted mining companies and the ASM sector.\nHowchin reflected on the need for a broader conversation regarding how society views responsibility in the mining industry. Davy considered that, through industry partnerships and cooperation with UNEP and PRI, “conduits of influence” that reach beyond listed companies are possible.\nHowchin concluded “Mining is not tobacco: it’s not something we can divest from; it’s the backbone of global industry.” He noted the insurance industry is interested in understanding which mining investments are better and safer investments.\nSession 4: Building Resilient Communities: Can We Leverage Impact Investment Mechanisms?\nIsabelle Ramdoo, Deputy Director, IGF Secretariat, introduced this session on Tuesday. Åsa Borssén, Series Host and Program Coordinator, Highgrade Media, moderated the first part of the session, which discussed the role of impact investment in communities and their resilience.\nElias Masilela, Chair, Impact Investing National Task Force, South Africa, outlined different types of investors, stating the present-day impact investor is a long-term investor that aims to weather economic cycles and secure positive returns for at least two generations. He said the major difference between an environmental, social and governance investor and an impact investor is that the impact investor asks “What is the change I want to bring about in the environment, so I can maximize my profits over a long period of time.” Masilela said investment is still largely privately sourced and thus requires governments to provide the right investment environment.\nMark Cutifani, Chief Executive, Anglo American, said mining companies’ relationships with communities are changing from “paternalistic relationships” to true partnerships that look towards the future of local communities beyond the life of the mine. Cutifani suggested impact investing look beyond corporate social responsibility as it invests in infrastructure to allow the long-term diversification of mining communities’ economic base, based on community needs. Noting that without community support, mining lacks a future, he said Anglo American looks to use automation of mines as a catalyst to create five offsite jobs for every one onsite job.\nRamdoo moderated the second part of the session, which addressed community perspectives, and examined the need to rethink community development support.\nTracey Cooper, Executive Director, Mining Dialogues 360°, stated that COVID-19 has created a greater awareness in communities to drive change. She cited, as an example, how South African citizen action networks have engaged with the private sector during hard lockdowns to ensure food security for the community and strengthen local food systems.\nShe noted communities’ awareness to demand higher levels of transparency in decision-making processes. She lamented “skewed power relations,” and suggested engaging community mediators to provide a neutral space for stakeholders to work together and create partnerships.\nCooper said impact investment makes the business case for long-term environmental and social investment, shifting the focus towards seeing action on the ground. She said consideration of impact investment at the planning stage for mining projects is key. She stressed a one-size-fits-all approach does not exist as each community is different.\nSession 5: Global Mine Closure Needs—Government and Industry Responses\nMatthew Bliss, IGF Secretariat, introduced this session on Tuesday. Moderator Jessica Bezuidenhout, Managing Director, Environmental Compliance Consultancy, stressed that mine closure is “a key pillar” in sustainable mining, and practice is continuing to evolve.\nPieter Swart, PhD Candidate, Sustainable Minerals Institute, University of Queensland, reported on a survey of 16 mining operations’ practices around mine closure. His research found that 75% of jurisdictions in the survey required mine closure plans, while 25% did not. The research also found that 75% of respondents lacked adequate agreement records around mine closure. He noted inadequate financial assurance for mine closure and said criteria for successful mine site rehabilitation are often not formally agreed.\nDawn Brock, Manager, ICMM, drew attention to the ICMM’s Integrated Mine Closure Guide, released in 2019. She explained governments are introducing more stringent requirements for mine closure. She recommended engaging early with stakeholders in post-mining transition planning, sharing knowledge, and promoting collaboration among governments, mining companies and stakeholders.\nAndrew Gunua, Chief Mining Warden, Mineral Resources Authority, Papua New Guinea (PNG), noted that PNG’s 1992 Mining Act had no provisions for mine closure, whereas its 2000 Environment Act has some provision for mine closure plans to be activated within five years of intended closures. He explained financial assurance at the outset will enable such plans to be implemented in the event of sudden closure of operations in various scenarios of abandonment, premature closure, or state refusal to renew a mining license. He stressed the need for indigenous engagement and representation.\nRaina Hattingh, Closure Planning Specialist, BHP, referred to IGF’s support in 2017-18 for the Namibian government to review its practices. The review found that recommendations made were often unenforceable. She stressed mine closure targets must be SMART (specific, measurable, achievable, relevant and time-bound), regulatory teams must have the technical capacity to implement regulations, and collaborative regulator-industry relationships are fundamental to developing mine closure solutions.\nAlberto Santos Capra, Director of Sustainable Mining, Ministry of Mining, Argentina, discussed the G7 CONNEX Initiative, which is advising the Ministry of Mining in Catamarca province. He reported a survey of mining companies in Argentina showed that 50% had a mine closure plan approved by the competent authorities. He noted a draft bill will be presented in 2021, and that mine closure recommendations are currently in place for three different mining projects that are approaching closure.\nParticipants asked about how technical capacity can be built during the COVID-19 pandemic. Hattingh encouraged everyone to consider using existing online training resources. She reminded governments that mining companies are often keen to have regulators visit their sites, and that they may be able to request flyovers and, when the opportunity returns, site tours.\nIn closing, Bliss highlighted an example of a cooperative approach in mine closure, in which a local community had requested the government continue providing electricity, which the company had been providing during the mining operation. In cooperation with the company, a hydro-electric arrangement was developed, driven by the downhill flow of water from the mine.\nSession 6: Responding to COVID-19 in the ASM Sector\nOn Wednesday, Alec Crawford, IGF Secretariat, introduced the session, which was moderated by Adam Rolfe, Senior Manager, Good Governance, Levin Sources.\nAïssatou Sophie Gladima, Minister of Mines and Geology, Senegal, highlighted actions including developing a new national ASM strategy and establishing a fund worth 100 billion West African Francs to support ASM miners during COVID-19.\nCarolina Rojas Hayes, Vice-Minister of Mines, Colombia, said the Colombian government had ensured personal protective equipment (PPE) was available to the sector, and USD 2.5 million was budgeted for temporary aid for ASM workers. She said the sector is expected to play a key role in economic recovery.\nOnline polls showed that participants believed governments should focus on economic recovery of the ASM sector and were generally optimistic about the sector in 2021.\nRachel Perks, Senior Mining Specialist, World Bank, together with Nathan Schneck, Pact, presented on the impacts of COVID-19 on the ASM sector, drawn from data collected by the Delve Project—a global platform for ASM data in order to better understand and meet the needs of the sector. Key messages included:\nCOVID-19 infections in ASM communities will adversely impact human capital development; little gender discrimination exists in accessing work; female miners are more food-insecure, a vulnerability the pandemic has exacerbated; and as ASM workers intend to continue mining, an opportunity exists to continue efforts to formalize the sector.\nPerks further pointed to a funding window offered by the World Bank to support ASM communities in light of the pandemic.\nRolfe, presenting on research conducted by Levin Sources, said challenges faced by ASM communities include limited health infrastructure availability. He underscored that informality is still prevalent in the sector, and policy responses must bear this in mind. He urged future ASM projects and programmes to differentiate between legitimate operations in the informal economy, and illegal and illicit mining activities.\nIn the ensuing discussion, participants underscored the need for a consensus among policymakers that strategies for ASM-dominated countries must include formalization to sustainably develop the economic sector.\nSession 7: Future of Resource Taxation: Challenges and Opportunities\nÅsa Borssén, Series Host and Program Coordinator, Highgrade Media, introduced the speakers at this Wednesday session. Participants watched a video on the IGF and the African Tax Administration Forum (ATAF) project, “The Future of Resource Taxation,” which aims to improve mining taxation systems in developing countries.\nAlexandra Readhead, IGF Secretariat, highlighted opportunities and challenges from recent automation and digitization of the mining sector, as low-skilled jobs decreased, diminishing payroll taxes and other economic benefits. She argued that global demand for minerals essential to the low-carbon energy transition are a chance for countries to capture more of the mining value chain and benefit from higher resource prices.\nBeatriz Olivera, Researcher, Fundar, Center for Analysis and Research, said Mexico’s mine fund, supported by companies, lacked accountability. She called for decentralization of such resources, greater efficiency, greater accountability, and fighting corruption.\nSegolo Lekau, Acting Commissioner General, Botswana Unified Revenue Service, explained that Botswana’s partnership with private-sector mining companies since the country’s independence in 1966 meant that decisions could be taken in the interests of citizens. He stated the crucial factors in this arrangement’s success included adherence to the rule of law, transparency of taxation arrangements, and ceding of mineral rights from the counties to the state, so benefits can be distributed equitably.\nDavid Murray, Tax Policy Principal, Anglo American, remarked that royalties may deliver a higher share of returns, but overall returns may be smaller.\nWayne Swan, former Treasurer and Deputy Prime Minister, Australia, called for addressing multinational tax evasion, especially transfer pricing and debt dumping. He noted his government’s attempt to introduce a new resource rent tax in 2010 had not survived, due to mining companies’ “propaganda.” He stressed the first step in tax reform must be to mobilize public opinion to oppose powerful vested interests.\nLogan Wort, Executive Secretary, ATAF, said a public campaign should address not only multinational corporations’ behavior, but also government complicity in corruption. He urged political will at the African Union level to consider key issues around extractive industries’ sustainability.\nParticipants posed questions about how a fair share of benefits from mining can be defined, what financial reserves should be created for post-mining rehabilitation, whether mining companies can offset corporate taxes by providing public goods, and what strategies, besides litigation, can be applied to resolve disputes.\nReadhead observed that governments need expertise to correctly assess the value of mineral exports. Swan highlighted Australia’s 2013 transparency legislation, which requires all large companies to publish their total taxable income and tax paid, saying the law had resulted in huge repayments to the government.\nSession 8: COVID-19 and the Future of Responsible Sourcing\nModerator Alec Crawford, IGF Secretariat, introduced this session on Wednesday. Yannic Kiewitt, Chair, European Partnership for Responsible Minerals (EPRM), said COVID-19 exposed the fragility of many responsible sourcing programmes. He stated the EPRM can assist with responsible sourcing through mobilizing resources, sharing knowledge and experiences, and raising awareness on responsible sourcing. He drew attention to the forthcoming entry into force of the EU Regulation on Responsible Sourcing of Minerals in January 2021, underscored the EPRM’s due diligence hub, and called for producer countries to engage with the EPRM on these issues.\nLouis Maréchal, Minerals and Extractive Sector Lead, Organisation for Economic Co-operation and Development, said responsible sourcing policies have had minimal negative impact from COVID-19, in stark contrast to the on-the-ground impacts of the pandemic. He also noted governments have continued to engage on incentive measures, if they were already doing so prior to the pandemic.\nNobuhle Mabhikwa, Programs Officer, Zimbabwe Environmental Law Association, said that in the Zimbabwean context, a national shutdown resulted in halting production, wage insecurity, price increases in input products due to border closures, foreign currency shortages, and additional costs of incorporating COVID-19 responses post-lockdown.\nVirginie Bahon, Head of Corporate Affairs, Valcambi, pointed to lower export volumes due to a lack of flights. She said Valcambi has had to assist with some mines’ liquidity, and onboarding new mines is problematic due to difficulties in conducting site visits.\nNatalia Uribe, Standards and Certification Coordinator and CAPAZ Supply Chains of Peace Project Leader, Alliance for Responsible Mining, noted payroll difficulties for Colombian ASM workers, price increases on goods to maintain safety protocols, and increased activity from illegal groups. She said areas for intervention include taking differentiated approaches in mining laws and integrating ASM into international supply chains.\nLotte Hoex, Conflict and Natural Resources Researcher, International Peace Information Service, noted trends in the pandemic’s impact on ASM and the supply chain, such as difficulties exporting goods, and a lack of liquidity forcing miners to accept lower commodity prices. Hoex lauded the sector’s resilience but said the pandemic exposed inequalities and showed that illicit miners received the best profit margins. These, she stated, underscore the critical importance of supply chain due diligence.\nDuring the discussion, participants queried ongoing challenges in the gold supply chain, and questioned whether any changes had been made in how companies are ensuring due diligence in their gold sector operations.\nSession 9: Future of Resource Taxation: Exploring Alternatives\nThis session took place in two parallel sub-sessions on Wednesday.\nSplitting the Proceeds: This sub-session addressed gross profit split, production sharing, and a simplified resource rent tax. Thomas Lassourd, IGF Secretariat, introduced the speakers, and Mary Baine, Director of Tax Programs, ATAF, moderated the discussion.\nWilfredo Moncano, Acting Director, Mines and Geosciences Bureau, the Philippines, explained that the Government of the Philippines engages in profit-sharing agreements, whereby the partner mining company first recoups its pre-production costs during a “recovery period,” before government taxes are paid. He noted challenges, including lack of transparency around the true financial status of partners and the actual recovery period. He suggested the Mines and Geosciences Bureau, with other government agencies, should determine the length of the recovery period. He also recommended enhancing information sharing with mining communities regarding fiscal, financial and technical agreements supporting mining projects.\nThomas Baunsgaard, Deputy Chief, Fiscal Affairs Department, International Monetary Fund, cautioned that moving away from profit-based to production-based approaches, such as royalties, joint ventures and state equity participation, would not necessarily solve tax avoidance. He said this may, in fact, increase the marginal cost of production, thus deterring investment. He recommended linking royalties to commodity prices. He proposed a forward-looking regime would: impose natural resource rents in the source country, ensuring a reasonable level of revenue from the start of production, including through a cash flow tax; adopt transparent pricing arrangements; promote collaboration between ministries and regulatory agencies; and have clear policy and tax frameworks, such as a combination of withholding taxes and “safe harbor” rules.\nVincent Kedi, Assistant Commissioner (License Administration), Ministry of Energy and Mineral Development, Uganda, remarked that mining has provided negligible benefits to African countries, due to corporate tax avoidance. He stated Uganda’s intention to adopt production sharing, which, he said, has been implemented by the Democratic Republic of Congo, Senegal and Gabon.\nDaniel Mulé, Senior Policy Advisor, Tax and Extractive Industries, Oxfam, on behalf of Viola Tarus, Extractives Strategist, Oxfam, noted that, regarding the relative merits of production-based versus profit-based approaches, the stability and predictability of fiscal regime matters. He said tax increases do not necessarily lead to more revenue, citing differences in low- and high-priced environments, and the example of windfall taxes that capture higher shares of resource rent. She highlighted the role of transparency and the value of financial modeling in enabling appropriate decision making around risk, for example, from commodity price fluctuations.\nResponding to participants’ questions, Baunsgaard noted variation in pricing practices, with gold, for example, having transparent price indices, so value is easily assessed for royalty and income tax purposes. As an indicator of pricing transparency, he proposed considering whether sales are “a true market transaction” among non-related parties.\nChanging Roles of the State: Looking at the IGF and ATAF’s new initiative, “The Future of Resource Taxation,” this sub-session queried how current mining taxation systems can be improved, and alternative ways countries can maximize returns from their mineral wealth.\nPresenters discussed state participation and a model of competitive bidding for mining licenses as a way to improve revenue collection from the mining sector. Discussions delved into some of the innovative fiscal policies that governments are exploring, and heard about experiences from Afghanistan and Chile.\nSession 10: Mining, Climate Change, and COVID-19—How the Pandemic Has Impacted Global Actions\nAlec Crawford, IGF Secretariat, introduced this session on Wednesday. Participants viewed a short video on the “Race to Zero”—a global campaign to rally leadership and support from businesses, cities, regions and investors to commit to achieving net-zero carbon emissions by 2050.\nFollowing this, Nigel Topping, High-Level Climate Action Champion, UK, addressed the AGM, saying COVID-19 has spurred action and ambition to address climate change. Topping noted that the commitment of cities and large corporations to net-zero emissions has eased the way for governments to act. He cautioned change is not linear, but rather systemic, self-reinforcing, and difficult to predict. He urged the mining sector to join the “Race to Zero,” stating the ingenuity of the industry is critical for the energy transition. He cautioned value in the sector could be eroded if companies do not sign on.\nDaniele La Porta, Senior Mining Specialist, World Bank, provided an overview of the climate-smart mining initiative, and spoke on the impact of COVID-19 in this area. She said the sector has seen temporary price reductions, along with a decrease in new mining project investment. She underscored the value of strong community relationships to enable mine sites to reopen more rapidly. She stressed the importance of mining to contribute to “building back better,” noting this provides an opportunity to diversify and green mineral supply chains and ensure increased resilience. She urged governments and industry to maintain a long-term focus on environmental and social protection policies.\nMike Buxton, Associate Professor and Section Head for Resource Engineering, Delft University, highlighted pressure for the mining sector to reduce its emissions and green its energy consumption. He acknowledged the importance of automation, but stressed the need for discussing potential negative impacts. He questioned whether governments or the private sector should lead efforts to reskill and retrain affected workers.\nBenjamin Sprecher, Leiden University, echoed Buxton’s sentiments, and called for establishing positive relationships with local communities to address these issues. He said in the past, mutually beneficial relationships have led to profitable outcomes for the sector.\nIn closing, Crawford underscored the transition is underway and a sector-wide response to climate change is needed.\nSession 11: How Can a Shared Vision on Mining Promote Sustainable Development in Latin America and the Caribbean?\nOn Wednesday, Moderator Natascha Nunes da Cunha, Senior Extractives Sector Specialist, Inter-American Development Bank (IDB), explained the IDB has supported a process in some countries to strengthen public institutions, modernize practice, and seek broad consensus around mining for sustainable development.\nDaniel Kaufmann, NRGI, observed the COVID-19 pandemic has revealed the weaknesses of public health systems in many parts of the world, and encouraged totalitarian trends in some countries. He noted the related economic downturn has highlighted the need to diversify economies.\nMaría Cristina Güell, National Mining Policy Coordinator, Chile, described consultations involving 1,500 participants from national bodies, indigenous peoples’ representative organizations, and other stakeholders. She pointed to the development of 19 new initiatives through this process, to be implemented from 2021, to help ensure mining benefits are socially inclusive.\nJaime Gálvez Delgado, Deputy Minister of Mines, Peru, recalled a commission on sustainable mining had begun work prior to the pandemic, producing 80 recommendations, but that the implementation process had stalled due to the political situation. He outlined current consultations in two areas with good mining potential, in the north and south of Peru, respectively.\nLaura Ropolo and Sylvia Gimbernat, Subsecretaries, on behalf of Alberto Hensel, Mining Secretary, Argentina, noted that, under the country’s federal system, provincial-level governments manage mining policies and contracts. Ropolo said from December 2020, consultations will begin towards a common vision for the next 30 years.\nPanelists considered lack of trust to be the main obstacle to successful stakeholder dialogues. They stressed participation processes must be legitimate and well-coordinated. Gálvez noted the difficulty of inter-agency coordination among specialist agencies. He said legal frameworks to support and give stability to public-private cooperation are needed.\nSession 12: Community Engagement During COVID-19: Challenges and New Opportunities\nOn Thursday, the AGM’s third and final day, Marina Ruete, IGF Secretariat, welcomed session participants. Susan Joyce, President, On Common Ground, introduced a video on the impact of the pandemic on indigenous peoples in South America. In online polls, participants expressed their view that the top challenge for communities has been loss of employment, followed by economic and food insecurity.\nNatascha Nunes da Cunha, Senior Extractives Sector Specialist, IDB, highlighted that the social license to operate remains a top issue for miners and stakeholders, and that communities are now better-informed and more vocal about their rights and needs. She explained the IDB is facilitating multi-stakeholder dialogues to help find common ground.\nRocio Avila, Latin America Regional Program Coordinator for Extractive Industries, Oxfam, explained the COVID “new normal” is marginalizing communities that lack access to digital technologies. She underscored that measures to boost the economy should prioritize human rights, transparency, and environmental protection. Measures to promote economic development and work opportunities, she said, should ensure equal opportunity for both women and men.\nNarcisse Dushimimana, Head of Mining Regulation and Inspection, Rwanda Mines, Petroleum and Gas Board, said, although the Rwandan government had allowed mining operations to continue as an essential service, around 19,000 jobs were lost due to border closures between neighboring countries, travel restrictions and disruptions to supply chains as a result of the pandemic.\nAna Cunha, Director of Government Relations and Social Responsibility, Kinross Gold, Brazil, recounted the company’s efforts to understand community needs through a stakeholder survey conducted by an NGO partner, followed by implementation of more than 40 social projects.\nDaniel Kauffman, NRGI, said COVID-19 has created opportunities, including the chance to develop a consensus for the future at the local level, around how resource extraction can benefit local communities. He also praised the awareness COVID-19 has created of the need for a healthier, cleaner planet.\nJoyce asked about the opportunities that currently exist to do things differently and questioned how “building back better” relates to community engagement. Avila responded saying companies and governments should use COVID-19 to recognize and acknowledge communities’ autonomy and build on this to create better channels of communication and dialogue. Dushimimana said opportunities in Rwanda center around ensuring employment levels remain at least similar to those pre-COVID-19, including through incentivized government recovery programmes.\nCunha reflected that the pandemic has provided an opportunity to increase awareness of communities’ ability to partner with mining companies to be a part of the solution and find more sustainable pathways. Nunes da Cunha underscored the importance of consensus building around the role of mining companies in sustainable development.\nSession 13: IGF General Council\nCouncil members met in a closed session on Thursday.\nSession 14: Opportunities for Greater Gender Equality: Assessing Gendered Impacts of Mining Before Project Development\nOn Thursday, Ege Tekinbas, IGF Secretariat, welcomed participants. Moderator Adriana Maria Eftimie, Social Development Specialist, International Finance Corporation, announced the IGF, with International Women in Mining, have collaborated with GOXI, an online platform for dialogue on governance of extractive industries, to map policy tools and implementation on gender in mining. She noted the lack of gender-disaggregated data and recommended such data collection begin early in the life of a project.\nMiriam Padolsky, Director, Science Policy Division, Impact Assessment Agency of Canada, outlined the 2019 Canadian Impact Assessment Act that makes it mandatory to consider the intersection of sex, gender and other factors—referred to as “gender-based analysis plus” (GBA+)—when assessing the impacts of major projects on federal lands in Canada, or lands outside of Canada. She explained mining projects affect indigenous territories, and therefore GBA+ provisions enable assessing impacts on indigenous rights, with government funding available to support public participation.\nIan Thomson, Policy Specialist, Extractive Industries, Oxfam, highlighted Oxfam’s guide on how to incorporate gender issues when conducting impact assessments. He called for including local expertise in assessments. Participants then viewed a video from Cambodia, which showed how Oxfam has partnered with the Highlander Association in Rattanakiri province to support gender impact assessments. The project used a mobile app to collect and share data among villagers, which, he noted, played a role in supporting community negotiations with a mining company.\nMónica Galeano Velasco, Gender Advisor, planetGOLD project, UN Development Programme (UNDP), introduced the project, which was undertaken in collaboration with Colombia’s Ministry of Mining and supported by the Global Environment Facility. She drew attention to Colombia’s launch of the mining sector’s first ever gender policy guidelines. She described current monthly talks organized by the planetGOLD project, in which participants discuss topics related to,\ninter alia, gender-based violence, impact of mercury on pregnant women, and sexual abuse.\nAmparo Cornejo, Vice President, Chile Sustainability and Corporate Affairs, Teck, stressed mining should not increase gender inequality. She lamented industry “has a long way to go” to ensure the benefits of mining are truly shared with women and vulnerable groups. She described research conducted with 420 indigenous women in Chile as the basis for a social programme addressing health, wellbeing, and support for small businesses.\nSession 15: Rethinking ESIA at the Early Phase of Mine Development\nClémence Naré, IGF Secretariat, introduced the session on Thursday, noting it aimed to discuss the role ESIAs can play in responsible mining. Moderator Paula Dobbelaar, Technical Secretary, Netherlands Commission for Environmental Assessment, pointed to challenges for the mining sector as demand shifts from fossil fuels towards renewable energy. She stated ESIAs play an important role in ensuring governments take responsible decisions. She drew attention to the increasing difficulty of conducting ESIAs in the mining sector due to the growing complexity of mining operations. She urged that ESIAs be conducted early on in the planning phases of mines.\nClémence Naré presented the IGF document, “Guidance for Governments: Improving legal frameworks for environmental and social impact assessment and management,” which provides tools, strategies and case examples for assessing and improving legal frameworks for ESIA and management. She said the guidance: links project phases to company and government responsibilities; provides an overview of good legal frameworks for ESIAs; and offers tools to assess whether legal frameworks truly respond to local communities’ demands and expectations.\nAmparo Cornejo, Vice President, Chile Sustainability and Corporate Affairs, Teck, affirmed that the most pressing challenges relate to ensuring environmental impacts are understood by communities. She said their engagement process strives for transparency on this issue. She noted Teck’s early engagement to understand community concerns for incorporation in ESIAs. She said COVID-19 has meant technology has had to be used to continue community engagement, which, while adequate, is not as effective as in-person meetings.\nDobbelaar draw attention to the use of strategic environmental and social assessment (SESA) as a tool for national governments. She presented a video on the use of SESAs in Guinea, showing clips of interviews with Karim Samoura, Netherlands Commission for Environmental Assessment, and Michel Pothier, Director of Operations, Anglo-African Minerals. Both, she said, have used SESAs to ensure better coexistence of mining activities with national parks and the construction of a hydro-electric dam.\nTeresa Macayo Marín, Environmental Mining General Director, Ministry of Energy and Mines, Peru, stated that the Peruvian legal framework allows less complex ESIAs when early stage exploration activities are being conducted. She said this was allowed following industry concerns that government expectations for ESIAs did not correspond to the project’s complexity.\nSession 16: Technical Innovation in a Post-COVID-19 Era: Changing the Face of Mining?\nOn Thursday, Aaron Cosbey, IGF Secretariat, and Åsa Borssén, Series Host and Program Coordinator, Highgrade Media, invited participants to discuss how COVID-19 may have accelerated the application of new technologies in the mining sector and to comment on future trends.\nHenrik Ager, President, Sandvik Mining and Rock Technology, anticipated that technology will be adopted to undertake operations remotely, for example, with the application of virtual reality tools and the use of drones for mapping the best transport routes in underground mines. He observed, however, that the mining industry is traditionally conservative, noting operations such as the Syama mine in Mali, the world’s first fully automated mine, are still rare due to companies’ fear of production disruptions caused by technology failure. He anticipated greater demand in the future for computing and programming abilities, and a decline in “handyman” skills.\nAlejandra Wood, Executive Director, Center for Copper and Mining Studies, Chile, noted that digital technologies, such as robotics, are being widely adopted in mining, and a window of time exists to prepare the workforce to work in areas such as cybersecurity, data management and automation. She said, based on research done in the Andean region, digital technologies can contribute to productivity of the circular economy and open spaces for jobs, procurement and innovation, thus compensating for any negative impacts.\nFroydis Cameron-Johansson, Group Head of International and Government Relations, Anglo American, drew attention to the role technology plays in removing gender stereotypes. She said this occurs, for example, as technology reduces the need for heavy physical labor, thus introducing more gender-neutral work roles, such as in operating control rooms and managing automated processes.\nShe called for encouraging more women and girls to work and study in the fields of science, technology, engineering and mathematics (STEM) and ensuring workplaces are fit for women. She underscored that acceptance of remote work, because of COVID-19, has “shown us the art of the possible.”\nSession 17: Closing Remarks\nAt the close of the meeting on Thursday, Greg Radford, Director, IGF Secretariat, remarked the meeting’s virtual format had enabled greater participation, with over 1800 people from approximately 110 different countries registered for the event.\nCarolina Rojas Hayes, Vice-Minister of Mines, Colombia, said the minerals sector in Colombia has proven to be resilient. She said the ability to operate throughout the pandemic has allowed the sector to adapt more easily. She underscored close collaboration with local authorities and communities was essential. She stated that as mining is key to Colombia’s economic recovery, the government is working on a strategy that encompasses: stronger, more efficient institutional frameworks; diversifying the mineral matrix towards minerals essential for the energy transition; and recognizing the legal status of ASM miners.\nMark Cutifani, Chief Executive, Anglo American, said the industry needs to understand and articulate where it fits in society, and, more specifically, in relation to local communities. He underscored partnership with local communities as essential to ensure continued positive, long-term contributions to society. He posited that the pandemic has allowed people to better understand how societies work. He said the mining industry has a role to play in being a catalyst for health and safety in the home by ensuring safety in communities. He stated that COVID has provided an opportunity to make sure mining works for everyone.\nRadford anticipated that, given the success of the virtual format, future AGMs may adopt a hybrid approach, bringing together face-to-face and online participation to continue the broad engagement seen at this AGM. He closed the meeting at 5:25 pm CEST.\nUpcoming Meetings Gender and Mining Governance: IGF, with UNDP Learning for Nature, is offering this online course on ways to: foster women’s equal engagement in mining projects; take action to eliminate gender-based violence in affected communities; and ensure investment in gender equality and women’s leadership in mining governance can lead to stable and resilient communities. The course takes place over four weeks and is free. dates: 2-27 November 2020 location: online www: https://www.learningfornature.org/en/courses/gender-and-mining-governance/ Seminar on Mine Tailings Safety in the UNECE Region and Beyond: This seminar will convene in advance of the 11th meeting of the Conference of the Parties on the Convention on the Transboundary Effects of Industrial Accidents, where parties are expected to adopt a decision on strengthening mine tailings safety in the UNECE region and beyond. date: 1 December 2020 location: online www: https://www.unece.org/index.php?id=55197 Virtual Tailings and Mine Waste 2020: This conference provides a platform for exchanging knowledge and skills related to tailings and mine waste, and future issues facing the mining and environmental communities. The conference was originally scheduled to take place in Keystone, Colorado, US, but was moved to a virtual setting due to COVID-19. dates: 15-18 November 2020 location: online www: https://tailingsandminewaste.com/program/ Investing in African Mining Indaba: The 2021 Mining Indaba will convene under the theme “Resilience to Rebuild: The New Mindset for Mining Operators and Investors.” It will bring together stakeholders to advance mining on the continent, and support education and sustainable development. dates: 1-4 February 2021 location: Cape Town, South Africa www: https://www.miningindaba.com/Home Getting to Equal in a Changing World: Second Global Gender in Oil, Gas and Mining Conference: This conference will explore gender equality in the oil, gas and mining sectors in the context of a changing world, particularly in light of the COVID-19 pandemic. It aims to provide a platform to: discuss policy, project implementation, and innovative approaches to address gender gaps; discuss progress made since 2018 in narrowing the gender gaps; identify the most pressing women’s rights issues facing the sectors; propose means of further collaboration to improve gender equality in extractive industries, and mitigate harm to women and girls in mining communities; and determine how to ensure follow up on progress and accountability. dates: 3-4 March 2021 location: online www: https://www.worldbank.org/en/events/2020/09/09/getting-to-equal-in-a-changing-world-second-global-gender-in-oil-gas-and-mining-conference Prospectors & Developers Association of Canada (PDAC) Convention: This convention on mineral exploration is expected to bring together more than 25,000 participants from 132 countries. PDAC 2021 will include: a Sustainability Program, featuring ways that companies are improving their sustainability performance; and an Indigenous Program, which will provide a platform for discussion on fostering cooperative, respectful and mutually-beneficial relationships between indigenous communities and the minerals industry. dates: 7-10 March 2021 location: online contact: Sustainability Program: Rose Stacey ([email protected]); Indigenous Program: Lesley Williams ([email protected]) www: https://www.pdac.ca/convention The Electric Mine 2021 Conference: This conference provides a platform to exchange ideas on best practices and discuss the unique challenges faced when trying to fully electrify mining operations in the face of increasing ventilation costs, deeper mine developments, and the need for miners to reduce their carbon footprint. Electrifying operations can reduce greenhouse gas emissions, improve the environment of mine workers, and cut both operational and capital expenses. dates: 15-16 March 2021 location: Stockholm, Sweden www: https://web-eur.cvent.com/event/43b430e6-9fdd-49b2-83a4-66e21ec9a8b5/summary Fifteenth Session of the UNCTAD Quadrennial Conference (UNCTAD XV): The conference is UNCTAD’s highest decision-making body, and sets the organization’s mandate and priorities every four years. A forum on mining and sustainable development will take place during the forum. Originally scheduled for October 2020, the Conference was postponed to April 2021 due to the COVID-19 pandemic. dates: 25-30 April 2021 location: Bridgetown, Barbados www: https://unctad.org/meeting/fifteenth-session-united-nations-conference-trade-and-development-unctad-15 Sustainable Minerals ‘21: The 6th International Symposium on Sustainable Minerals (Sustainable Minerals ’21) is the postponed Sustainable Minerals ’20. It will discuss all aspects of material and metal usage by considering, inter alia: clean technology, tailings disposal, environmental impact assessment methodologies, coal waste, carbon emission controls, and sustainability from an industrial as well as a consumer perspective. dates: 23-24 June 2020 location: Falmouth, Cornwall, UK www: http://www.min-eng.com/sustainableminerals21/ Third Copper Cobalt Africa Conference: This conference aims to promote dialogue among stakeholders, and enhance understanding of new and existing technologies. Topics to be addressed include recycling and urban mining, as well as waste treatment and minimization. dates: 13-15 July 2021 location: Livingstone, Zambia www: https://www.saimm.co.za/saimm-events/upcoming-events/copper-cobalt-africa# APCOM 2021: Applications for Computers and Operations Research in the Minerals Industries (APCOM) 2021 will provide a platform for industry and academia to exchange ideas on and discuss innovations in the sector. It will include sessions on environmental issues, including tailings management and mine closure, industry-wide projections, and mine planning and design. dates: 29 August–2 September 2021 location: Geneva, Switzerland www: https://apcom2021.com/ Standards and Opportunities for the Mine of the Future: This conference will include an exchange of knowledge and ideas on issues addressed by the recently published Global Industry Standard on Tailings Management and on guidance developed by the International Commission on Large Dams. It will bring together stakeholders in the sector to discuss, among other things, stakeholder engagement and affected communities, environmental impacts, and the possibility of mining with no tailings. dates: 8-9 November 2021 location: Sun City, South Africa www: https://www.saimm.co.za/saimm-events/upcoming-events/global-tailings-standards-and-opportunities-for-the-mine-of-the-future/ 17th IGF AGM: The dates: Autumn 2021 location: Geneva, Switzerland www: https://www.igfmining.org/\nFor additional upcoming events, see http://sdg.iisd.org/", "pred_label": "__label__POS", "pred_score_pos": 0.500225305557251}
{"content": "They’re essential to energy, focus, vitality, and metabolism. And yet most of us have no idea how our mitochondria work. Here’s how to tune up your body’s quadrillions of “energy factories” and avoid mitochondrial dysfunction.\n- Nutrition - By Pamela Weintraub\n- Functional Medicine - By Anjula Razdan\nMS expert — and patient — Terry Wahls, MD, on what the recent discovery means for those with the neurodegenerative disease.", "pred_label": "__label__POS", "pred_score_pos": 0.8198499083518982}
{"content": "Abstract\nTumors express peptide antigens capable of being recognized by tumor- specific cytotoxic T lymphocytes (CTL). Immunization of mice with a carcinogen-induced colorectal tumor, CT26, engineered to secrete granulocyte/macrophage colony-stimulating factor, routinely generated both short-term and long-term CTL lines that not only lysed the parental tumor in vitro, but also cured mice of established tumor following adoptive transfer in vivo. When either short-term or long-term CTL lines were used to screen peptides isolated from CT26, one reverse-phase high performance liquid chromatography peptide fraction consistently sensitized a surrogate target for specific lysis. The bioactivity remained localized within one fraction following multiple purification procedures, indicating that virtually all of the CT26-specific CTL recognized a single peptide. This result contrasts with other tumor systems, where multiple bioactive peptide fractions have been detected. The bioactive peptide was identified as a nonmutated nonamer derived from the envelope protein (gp70) of an endogenous ecotropic murine leukemia provirus. Adoptive transfer with CTL lines specific for this antigen demonstrated that this epitope represents a potent tumor rejection antigen. The selective expression of this antigen in multiple non-vital-induced tumors provides evidence for a unique class of shared immunodominant tumor associated antigens as targets for antitumor immunity.\nOriginal language English (US) Pages (from-to) 9730-9735 Number of pages 6 Journal Proceedings of the National Academy of Sciences of the United States of America Volume 93 Issue number 18 DOIs State Published - Sep 3 1996 Keywords cytotoxic T lymphocytes endogenous murine leukemia virus major histocompatibility complex class I peptides murine tumor antigens tandem mass spectrometry ASJC Scopus subject areas General", "pred_label": "__label__POS", "pred_score_pos": 0.9258706569671631}
{"content": "Jun is a Senior Associate in RMI’s Carbon-Free Cities and States team. She is currently developing open-access analytics for advocates and policymakers to accelerate climate action. These tools will be used to ensure that the United States meets its original commitments in the Paris Agreement.\nBackground\nJun joins RMI from Duke University’s Nicholas School of the Environment, where she received her PhD. Her research focused on using large, publicly available databases to explore the intersection of global energy systems and international trade. Prior to her doctoral studies at Duke, she was a research fellow at a state policy lab based in the economics department at Brown University. At Brown, she led policy evaluations using large administrative data and statistical methods. Jun was a Young Summer Scientist at the International Institute for Applied Systems Analysis (IIASA) in 2019, where her research was funded by the National Academy of Sciences.\nEducation\nPhD, Earth and Ocean Sciences, Duke University\nMPhil, Environmental Policy, University of Cambridge A.B., Environmental Science and Public Policy, Harvard University Location\nWashington, D.C.", "pred_label": "__label__POS", "pred_score_pos": 0.8572040796279907}
{"content": "Combine Harvester, or simply combine, is a versatile Machine designed to efficiently harvest a variety of grain crops. The name derives from its combining three separate harvesting operations—reaping, threshing, and winnowing—into a single process. Among the crops harvested with a combine are wheat, oats, rye, barley, corn (maize), sorghum, soybeans, flax (linseed), sunflowers and canola. The separated straw, left lying on the field, comprises the stems and any remaining leaves of the crop with limited nutrients left in it: the straw is then either chopped, spread on the field and ploughed back in or baled for bedding and limited-feed for livestock.\nCombine harvesters are one of the most economically important labour saving inventions, significantly reducing the fraction of the population engaged in agriculture.", "pred_label": "__label__POS", "pred_score_pos": 0.8601803779602051}
{"content": "Here’s What You Receive: FDA Authorizedantibody test for COVID-19 Same or Next-dayresults from a CLIA approved lab\nThe\nopportunity for confirmatory testingthrough PCR analysis\nOur serological test identifies the presence of antibodies indicating an individual has or had an immune response to the SARS-CoV-2 virus (also known as COVID-19 or coronavirus). As of May 7, 2020, the test utilized by Vanguard Genetics is\none of only 12 tests authorized by the FDA under Emergency Use Authorization and is available without the need for a prescription or health insurance.\nThis test identifies the presence of both IgM and IgG antibodies and as a result, can be used as an indicator of both past and present infection. However, this test is not to be used for sole diagnosis of an active infection. An indication of active infection should be followed up with a PCR screening, which is the “gold standard” for active infection screening.\nAntibody testing is generally for people who are not currently experiencing symptoms related to COVID-19. Current data indicates it may take up to 14 days after the onset of symptoms for antibodies to be developed within the body. However, 91% of individuals develop antibodies within the first 8-13 days.", "pred_label": "__label__POS", "pred_score_pos": 0.8840299844741821}
{"content": "This learning brief lets us know how the Community Conversation Approach can tackle gender inequalities. Community conversations are a socially transformative approach that galvanizes communities to address the underlying causes of underdevelopment and vulnerability. The approach provides a platform where a cross-section of the community members including local administrators, religious leaders, parents, teachers, community health workers, young men and women, converge and reflect on the challenges faced by the girls. They further identify steps to take to resolve these challenges and draw action plans that will eventually lead to a change in attitude, values, beliefs and practices that impede adolescent girls from realizing their full potential or well-being.", "pred_label": "__label__POS", "pred_score_pos": 0.9912514686584473}
{"content": "The global methionine market was valued at $5,114.3 million in 2017, which is projected to reach $9,121.9 million by 2023, progressing at a CAGR of 10.2% during the forecast period (2018–2023). The DL-methionine category, based on type, dominated the market in terms of revenue during the historical period (2013–2017).\nThe methionine hydroxy analog (MHA) category is expected to witness the fastest growth during the forecast period (2018–2023), among all types. This can be attributed to its properties, such as highly digestible and capable of increasing feed intake, which result in faster growth of young poultry and increased productivity of adult poultry.\nGrowing Preference for Bio-Methionine\nKey trend witnessed in the methionine market is the emergence of bio-methionine. Generally, methionine is derived from petrochemical sources, where raw materials used are hard-to-handle and hazardous in nature. Biochemical routes are being researched to obtain methionine. For instance, CJ Cheiljedang Bio and Arkema Group entered into a joint venture, to initiate methionine production from essential raw materials using innovative industrial process, owing to their environment-friendly nature and sustainability benefits over synthetic materials.\nIncreasing Poultry Consumption\nIncrease in global poultry consumption is one of the major factors driving the methionine market. As per the global poultry trend data, poultry meat uptake is forecast to increase by 1.7 kg per person from 13.2 kg in 2013 to 14.9 kg in 2023. With the increasing population, the demand for meat is also rising, thereby leading to surge in poultry consumption.\nSegmentation Analysis of Methionine Market\nThe liquid category is expected to witness faster growth during the forecast period in the methionine market, in terms of volume. Addition of liquid methionine in animal diet improves the growth performance as well as the morphology of gastrointestinal tract of piglets, and increase in the production capacity of liquid methionine by key market players are expected to drive the sale of methionine in coming years.\nThe DL-methionine category held the largest volume share in 2017 in the methionine market. This is ascribed to its high demand as nutritional and dietary supplement from the animal husbandry and food processing sectors.\nThe aquaculture category is expected to exhibit fastest growth during the forecast period. This can be ascribed to the high demand for aquatic organisms for consumption, which are one of the best sources of animal proteins.\nGeographical Analysis of Methionine Market\nTogether, APAC and Europe are expected to account for over 60% revenue in the methionine market by 2023. This can be mainly attributed to the presence of established players, modernization of the animal husbandry sector, and high-volume production of pork, poultry, and livestock in these regions.\nNorth America, LATAM, and MEA, also hold considerable shares in the methionine market, on account of the growing population, rise in methionine manufacturing units, and growth of the animal husbandry industry.\nThe U.S. is expected to lead the North American methionine market, generating revenue of over $1,483.2 million in 2023. The market in the country is mainly driven by the presence of key players, such as Novus International Inc. and Archer Daniels Midland (ADM) Company.\nBrazil is the fastest-growing market for methionine in the LATAM region. Growing population, rise in methionine manufacturing units, and increasing demand for meat are the major factors contributing to the growth of the market in the country.\nCompetitive Landscape of Methionine Market\nThe global methionine market is consolidated in nature, characterized by the presence of major players, such as Evonik Industries AG Corporation, Bluestar Adisseo, and Novus International Inc., which are engaged in the development and commercialization of methionine.\nIn March 2018, Bluestar Adisseo Company started the construction of new liquid methionine factory in Nanjing, China. This factory is designed to produce 180,000 tons of liquid methionine every year. After the completion of the new factory, Adisseo will be able to double its total capacity in Nanjing. The new factory is be expected to come into operation by the middle of 2021.\nSome other important players in the methionine market include Sumitomo Chemical Company Limited, Arkema Group, Archer Daniels Midland (ADM) Company, Ajinomoto Co. Inc., and BASF SE.", "pred_label": "__label__POS", "pred_score_pos": 0.8264250755310059}
{"content": "Anheuser-Busch InBev (AHBIF.PK,BUD) reported Thursday that its first-quarter loss attributable to equity holders was $2.25 billion or $1.13 per share, compared to restated net income of $3.57 billion or $1.80 per share in the previous-year quarter.\nNormalized loss attributable to equity holders of the company was $845 million, compared to restated normalized profit of $2.40 billion last year.\nNormalized loss per share was $0.42, compared to normalized earnings per share of $1.21 a year ago, negatively impacted by a lower profit and mark-to-market losses linked to the hedging of the company's share-based payment programs.\nUnderlying profit attributable to equity holders decreased to $1.02 billion or $0.51 per share from $1.45 billion or $0.73 per share last year.\nRevenue for the quarter declined to $11.00 billion from a restated $12.22 billion in the year-ago quarter, materially impacted by lower volumes resulting from the COVID-19 pandemic. On an organic basis, revenue declined 5.8 percent in the quarter, while revenue per hl grew by 3.9 percent.\nThe company noted that the impact of COVID-19 on its global results increased significantly toward the end of the quarter. Consequently, the company's total volume in the quarter declined by 9.3 percent, and by 3.6 percent excluding China.\nThe company's own beer volumes were down 10.5 percent and non-beer volumes were down 0.2 percent.\nLooking ahead, Anheuser-Busch InBev said it expects that the impact of COVID-19 on its second quarter results will be materially worse than in the first quarter.\nThe company noted that its April 2020 global volumes declined by approximately 32 percent, primarily driven by the closure of the on-premise channel in most markets and government restrictions imposed on certain operations of the company in connection with the COVID-19 pandemic.\nIn March, the company withdrew its outlook for fiscal 2020 due to the uncertainty associated with the pandemic.\nFor comments and feedback contact: editorial@rttnews.com\nBusiness News", "pred_label": "__label__POS", "pred_score_pos": 0.8811198472976685}
{"content": "Nurture provision is accessed by children who need additional specialised support. At Portland, Nurture is at the heart of the school, and is accessed by children and their families.\nSupport techniques offered at Portland Spencer include Play Therapy, Art Imaging and Emotional Understanding. Through 1:1 personalised therapy, we equip children with the skills to help themselves.\nPlay Therapy is non-directive and non-judgemental, offering children a safe place with boundaries to express their needs and discover the tools to explore their feelings and identify steps of action.\nArt Imaging is directed therapy which uses the medium of art to explore children’s feelings in a safe and supportive space.\nEmotional Understanding allows children to delve into their feelings, identifying triggers and using a range of techniques to help them understand why they feel angry, and how to resolve and release negative feelings.\nChildren learn more productive ways of releasing their feelings, communicating their feelings to the adults around them who can help them make better choices.", "pred_label": "__label__POS", "pred_score_pos": 0.82090163230896}
{"content": "A current transformer measures electrical currents. It creates a reduced current proportional to the circuit’s current (1/N x I) and isolates the circuit from the measuring equipment. Typically, to measure the current, you need a break in the circuit to connect the ammeter in series. You can place a current transformer at any location on a board without affecting the connectivity of the circuit.\nUnlike power transformers, current transformers don’t increase or decrease the voltage to power a piece of equipment. Instead, they simply measure the current running through a conductor and isolate the measurement from its source.\nCurrent transformers can use a toroidal or EI core. They use single turn and multi-turn windings. Typical turn ratios are 1 to 500 or 1 to 1000, indicating that the current through the winding can be reduced by 500 or 1000. This makes it possible to measure high currents safely and efficiently.\nApplications of a current transformer/current sensor include:\nMetering Coupling analog to digital circuits Sensing overload current Ground fault detection Load drop or shutdown", "pred_label": "__label__POS", "pred_score_pos": 0.9304711222648621}
{"content": "This work focuses on the impact of sharing contexts on consumers’ decision processes and purchase-amount decisions. Four studies, using both hypothetical and real (incentive-compatible) choices, find that people regularly purchase more in sharing (vs. non-sharing) contexts. Evidence is presented suggesting that a significant portion of this effect is driven by a cognitive bias arising in sharing contexts that focuses people on what they will give to others, and away from what they will receive from others. Consequences of this bias include the noted surplus in purchase amounts, over-consumption, and waste.", "pred_label": "__label__POS", "pred_score_pos": 1.000009298324585}
{"content": "What is Nephrolithiasis?\nNephrolithiasis, the disorder involving the formation of stones in the urinary tract, is a condition where the ureteral calculi or stones originate in the kidneys disrupting the functioning of the urinary tract system often leading to other infections and diseases.\nSymptoms\nPatients with Nephrolithiasis often experience pain and inflammation in the kidney and bladder area due to the presence of these stones. These vary depending on the location of pain, duration since stones are formed, and their characteristics. Some common symptoms include\nCramps and pain associated with nausea Difficulty in passing urine as it is obstructed by the stones Upper and lower abdominal pain as the stones migrate Pelvic ache Acute pain in the renal system due to infection Renal failure Abscess formation Tenderness and discomfort at any part of the urinary tract system Causes\nThere are a few causes and risk factors that can often lead to Nephrolithiasis. These include\nPast cases of urinary calculi Prior urinary tract complications and infections Renal failure and obstruction to the function Family history Elevated levels of Calcium, Oxalate, and Uric acid in urine Metabolic and harmonic abnormalities Excess calcium in diet Environmental factors Dietary changes Some hereditary and genetic factors HOMEOPATHY TREATMENT FOR NEPHROLITHIASIS\nKidney stones or Nephrolithiasis can be eliminated with effective Homeopathy. The treatment administered by Dr. Care not only ensures cure and relief from the problem but also future complications and side-effects will be avoided. This is the safest way to counter the symptoms of kidney stones and normal functionality of the urinary tract system can be achieved to full extent in a good time.", "pred_label": "__label__POS", "pred_score_pos": 0.6015713214874268}
{"content": "A crown is a cap or covering for a tooth. This is used to fix when your tooth is broken or cracked or heavily filled or even if lost fillings.\nCrowns come in a variety of materials and the cost varies depending on the chosen material. Our Kallangur dentists can recommend the perfect crown material during your first visit.\nOur dentists use their expertise and modern technology to match the new crown to the shape of your existing teeth and their colour.\nWhen would I need a crown?\nReplacement of a large filling If your teeth are heavily filled, they may be at risk of fractures. Frequent replacement of fillings can lead to loss of precious tooth structure. Repeated dental treatment on the same tooth may lead to deepening of the filling and subsequent nerve inflammation. To avoid these complications, your dentist may recommend that a crown is constructed before the filling becomes too large and remaining tooth structure is too short to support a crown. To stop a tooth from further cracking or fracturing If your tooth is showing fine lines and cracks or you occasionally feel sensitivity when biting into sticky or hard foods, your tooth may have a deep crack or may be at risk of complete fracture. This is common for heavily filled teeth, especially where an amalgam filling is in place. Your dentist may recommend a crown to restore the tooth and protect its cusps from splitting apart and may suggest replacing any amalgam with a ceramic restoration. To anchor a bridge replacing a missing tooth If a tooth is missing or lost, your dentist will discuss the options for tooth replacement. This may involve the placement of an implant or tooth supported bridge. If two or more teeth directly adjacent to the lost or missing tooth are at risk of fracture or are discoloured and need crowns, a bridge may be a good option to replace the missing tooth. When the bridge is produced, a porcelain tooth (pontic) is fused to the two or more crowns on either side and once the crowns are fitted onto the adjoining teeth, the porcelain pontic appears to be emerging out of the gum. A bridge may be a suitable course of treatment for you if you are unable to have an implant due to issues with your overall health or dental health. After root canal treatment Root canal filled teeth are prone to fractures, due to the nature of root canal treatment and hollowing out of the tooth in the process. Dentists highly recommend crowning most root canal filled teeth to protect them from fractures and further bacterial infections. Cover discoloured or worn teeth If you feel that your teeth are becoming more transparent or becoming darker in colour, they may be wearing down. Your dentist will discuss the reasons behind this as it is important that they are addressed first. If your dentist recommends a crown restoration, then this crown will be fabricated to resemble the natural shape and strength of your existing tooth through the use of a ceramic material.", "pred_label": "__label__POS", "pred_score_pos": 0.6085593700408936}
{"content": "In general, the law considers the husband to be the father if the parents were married when the child was born. Parents who are not married when a child is born can sign a voluntary declaration of paternity to establish paternity. These steps simplify matters.\nHowever, people who are not married may not be able to agree about parentage. These decisions are especially important when seeking child support, child custody, or child visitation rights. Our practice can guide you in establishing your rights.\nPaternity and DNA Testing\nIf you and the parent of a child are not married and cannot agree about parentage, the court can order genetic testing.\nThe mother, child, and alleged father will be required to submit to these blood tests. If a party refuses, the court can automatically decide against him or her. The judge may also rule on child support, custody, and visitation as part of the same case.\nWorking with Attorney Charles M. Green\nCases such as these require an experienced Los Angeles paternity lawyer. Charles M. Green provides this type of knowledgeable and dedicated representation.\nMr. Green is a family law specialist as certified by the Board of Legal Specialization by the State Bar of California. He is recognized by his peers, colleagues, and courtrooms for his professional accomplishments and approach, and he has worked with many clients like yourself who have gone through these complex and difficult issues.\nBy relying on Mr. Green for your case, you will benefit from sound legal guidance; effective trial counsel; and a supportive advisor committed to your success.", "pred_label": "__label__POS", "pred_score_pos": 0.843590497970581}
{"content": "As the Christmas season draws closer, the Bureau of Customs (BOC) reiterates the guidelines in sending balikbayan boxes to the Philippines.\nThese packages can be sent even by corporations, partnerships, and sole proprietors, but the BOC said qualified Filipinos while abroad (QFWA) can only avail of the duty- and tax-free privilege under the Section 800 (g) or the Republic Act No. 10863 or the Customs Modernization and Tariff Act 2016 (CMTA).\nThe law states that sending of balikbayan boxes by QFWA to their families and relatives is also exempt from payment of duties and taxes up to three times and the total freight on board (FOB) or free carrier arrangement (FCA) value of which, shall not exceed P150,000 in a calendar year.\n“Any amount that exceeds the allowable value is subject to payment of duties and taxes,” the BOC said.\nThe QFWA classifications covers Overseas Filipino Workers (OFWs) with valid passports issued by the Department of Foreign Affairs (DFA), certified by Department of Labor and Employment (DOLE) and Philippine Overseas Employment Administration (POEA) for overseas employment.\nThis also includes Filipinos under job contracts not requiring certification from the foregoing. Non-resident Filipinos with permanent residency abroad but have retained Filipino citizenship are also covered by the guidelines, as well as resident Filipino citizens that may include holders of student visa, investors’ visa, tourist visa, and similar visas which allow them to establish temporary stay abroad.\n“To avail (themselves) of this privilege, the Bureau also reminds Filipinos that balikbayan boxes should contain only personal and household effects such as wearing apparel, personal adornment, gadgets, and toiletries to qualify for the tax exemption. Goods which are in commercial quantities and those intended for sale, hire, or barter, are not covered by the duty- and tax-free privilege,” it added.\nThe QFWA or sender shall submit an accomplished information sheet, photocopy of a biographical page of passport or other identification cards (IDs) indicating citizenship, and invoice or receipt if available, to an international forwarder or consolidator.\nThe hired international forwarder or consolidator shall then submit all documents, including Information Sheets, to the BOC and Philippine forwarder or deconsolidator in a secured electronic format.\nThe Philippine forwarder or deconsolidator shall also submit all documents, including the Information Sheets, received from the consolidator, to the BOC in a secured electronic format.\nIn line with the BOC’s drive to promote transparency and ease of doing business, the Parcel and Balikbayan Tracking System was also launched last October 2019 to render a more efficient means of tracking parcels and balikbayan boxes accessible through customs.gov.ph.\n“Senders are highly encouraged to utilize the system which will provide updates about their shipment as it goes through the different stages of customs clearance,” the BOC said.\nAs the volume of such shipments increase during the holiday season, the BOC also reminds the public to be cautious in sending their packages and parcels.\n“OFWs and claimants are advised to support legitimate and accredited forwarders to avoid the possibility of being scammed by fly-by-night operators,” it added.", "pred_label": "__label__POS", "pred_score_pos": 0.7806424498558044}
{"content": "A leadership model for federal leaders during times of crisis\nIt’s been one year since we released the standard for effective government leadership, with our Public Service Leadership Model. And it’s clear from our work with federal leaders that these values are resonating as the nation navigates these turbulent and uncertain times.\nThe model is particularly important now as the public turns to leaders to listen to their concerns, share a vision of hope and make thoughtful decisions.\nThe model emphasizes the core values unique to public service: stewardship of public trust and commitment to public good. And it identifies the critical competencies leaders must master to achieve their desired impact.\nThe strong positive response we’ve received confirms the need for a clear standard in public service leadership. But we didn’t want to stop with a resonant concept. Since its release we’ve put the model into action and provided additional resources and tools to support federal leaders in their ongoing development.\nRecently, the Harvard Business Review published our article highlighting the model’s practical uses. And we updated our website to help federal leaders incorporate the model into their own leadership development, providing reflective questions and resources, including videos and blog posts from our Government Leadership Advisory Council. We’ve also launched new programs centered on the model’s core tenets and made significant changes to our existing professional development courses, such as the Excellence in Government Fellows program, to align them with the model’s leadership competencies.\nAnd we’re just getting started.\nWhat’s next for the leadership model\nIn an exciting development, we’re integrating our recently released Public Service Leadership 360 Assessment Tool into our programs and partnering with agencies that want to use it to assess their employees. The 360 assessment provides leaders with a broad view of their leadership style, and insights into how their perspective differs or aligns with those of their colleagues. If the leadership model is a map to help federal leaders identify the destination of their leadership journey, the 360 assessment serves as a compass, providing guidance and focus so they can strengthen their self-awareness to shift their management behaviors.\nIf all federal leaders grounded themselves in the core values and harnessed the key competencies from the model, we would have a stronger government and stronger country, better equipped to respond to crises like those we’re navigating today. As we celebrate the one-year anniversary of the model’s release, the Partnership is looking ahead to its future and how the model can be used to support the vast potential for public service leadership.\nLearn more about the Public Service Leadership Model on our website and on our blog:\nFour tips to help you complete a self-assessment How a Sammies finalist solved a health crisis mystery tied to vaping Are you an agitated leader? Here are four tips to help you stay “CALM”", "pred_label": "__label__POS", "pred_score_pos": 0.5237193703651428}
{"content": "Our courts have a duty to place the best interest of children first. Unfortunately, this is not always a duty parents take seriously with some often letting personal feelings get in the way and using their kids as pawns in their ongoing battles with their exes.\nThe Pretoria High Court sent a strong message today that this behaviour is unacceptable, by sentencing a mother to 30 days in jail for denying her ex-husband access to their 3-year-old. The punishment was suspended for five years, as long as the mother allowed her ex-husband access.\nIn 2011, the mom and her ex entered into a divorce settlement agreement, which was made a binding order of court. They agreed that the child’s dad could see his son every second weekend and during holidays, but despite attempts to exercise his right, the mother outright refused. Consequently, the mother was found to be in contempt of court for failing to comply with the order. Continue reading “Battle of the Exes”\nThe film follows young adults fighting to reunite with their broken families. It took years for the filmmakers to find young adults willing to go on camera to tell their stories as many did not want to talk about being brainwashed to hate a parent after a divorce, due to shame. Family courts are often overwhelmed with cases, and few protocols exist to help these families, forcing them to fight for custody instead of helping them to be co-parents. Yet there is a happy ending as these broken families are being reunited on screen, which will inspire other children to reach out to their own erased parents. It also highlights how showing the reforms to make separation of the parents healthier is urgently needed.\n“Joint Custody is still not the norm, and many bar associations oppose making it the default option as there is a lot of money to be made in custody battles,” said Gentile. “Right now, only one state, Kentucky, has such a law passed in 2018.” Continue reading “Erasing Family Documentary About Child Custody After Divorce”\nWhen caregivers conflict, systemic alliances shift and healthy parent-child roles can be corrupted. The present paper describes three forms of role corruption which can occur within the enmeshed dyad and as the common complement of alienation and estrangement. These include the child who is prematurely promoted to serve as a parent’s ally and partner, the child who is inducted into service as the parent’s caregiver, and the child whose development is inhibited by a parent who needs to be needed. These dynamics—adultification, parentification and infantilization, respectively—are each illustrated with brief case material. Family law professionals and clinicians alike are encouraged to conceptualize these dynamics as they occur within an imbalanced family system and thereby to craft interventions which intend to re-establish healthy roles. Some such interventions are reviewed and presented as one part of the constellation of services necessary for the triangulated child.\nDivorce Casualties helps parents recognize the often subtle causes of alienation and teaches them how to prevent or minimize its damaging effects. Dr. Darnall gives readers practical, specific techniques for recognizing and reversing the effects of alienation including a self-report inventory to help parents assess their own alienating behavior and exercises to help them understand and modify it.", "pred_label": "__label__POS", "pred_score_pos": 0.6561264395713806}
{"content": "Abstrakt\nMagnetic levitation is a technique for measuring the density and the magnetic properties of objects suspended in a paramagnetic field. We describe a novel magnetic levitation-based method that can specifically detect cell membrane-bound and soluble antigens by measurable changes in levitation height that result from the formation of antibody-coated bead and antigen complex. We demonstrate our method's ability to sensitively detect an array of membrane-bound and soluble antigens found in blood, including T-cell antigen CD3, eosinophil antigen Siglec-8, red blood cell antigens CD35 and RhD, red blood cell-bound Epstein-Barr viral particles, and soluble IL-6, and validate the results by flow cytometry and immunofluorescence microscopy performed in parallel. Additionally, employing an inexpensive, single lens, manual focus, wifi-enabled camera, we extend the portability of our method for its potential use as a point-of-care diagnostic assay.", "pred_label": "__label__POS", "pred_score_pos": 0.7862650156021118}
{"content": "Abstract\nSediment caps that degrade contaminants can improve their ability to contain contaminants relative to sand and sorbentamended caps, but few methods to enhance contaminant degradation in sediment caps are available. The objective of this study was to determine if, carbon electrodes emplaced within a sediment cap at poised potential could create a redox gradient and provide electron donor for the potential degradation of contaminants. In a simulated sediment cap overlying sediment from the Anacostia River (Washington, DC), electrochemically induced redox gradients were developed within 3 days and maintained over the period of the test (∼100 days). Hydrogen and oxygen were produced by water electrolysis at the electrode surfaces and may serve as electron donor and acceptor for contaminant degradation. Electrochemical and geochemical factors that may influence hydrogen production were studied. Hydrogen production displayed zero order kinetics with ∼75% Coulombic efficiency. Rates were proportional to the applied potential between 2.5 and 5 V and not greatly affected by pH. Hydrogen production was promoted by increasing ionic strength and in the presence of natural organic matter. Carbon electrode-stimulated degradation of tetrachlorobenzene in a batch reactor was dependent on applied voltage and production of hydrogen to a concentration above the threshold for biological dechlorination. These findings suggest that electrochemical reactive capping can potentially be used to create \"reactive\" sediments caps capable of promoting chemical or biological transformations of contaminants within the cap.", "pred_label": "__label__POS", "pred_score_pos": 0.6155831813812256}
{"content": "Abstract\nSubstance use and abuse has become an issue for adolescents globally. While multiple factors contribute to substance use, peer influence is particularly important. As such, this study aimed to examine students’ beliefs related to substance use, including the role peers have on substance use behaviors in Monrovia, Liberia. Nine focus groups were conducted with a total of 72 public school students in Monrovia. All focus groups were recorded, transcribed verbatim, and analyzed by a team of trained, qualitative coders. Per student report, peers both directly and indirectly influenced decisions related to substance use. Direct influence from peers included peer pressure, bullying and taunts, and putting drugs or alcohol into food and drinks to be consumed by peers without their knowledge. Indirect influence occurred when peers witnessed the substance use behaviors of others. Despite this, there was a subset of individuals who refused peer pressure, citing a number of reasons, including future negative outcomes. Given the central role that peers play in the substance use behaviors of adolescents in the Liberian cultural context, public health policies and interventions should target these interactions.\nKeywords Liberia adolescents peers qualitative substance use ASJC Scopus subject areas Health(social science) Developmental and Educational Psychology Sociology and Political Science", "pred_label": "__label__POS", "pred_score_pos": 0.9996153712272644}
{"content": "This is where we begin to define the signs of autism and the corresponding treatments. Many of the signs of autism are portrayed in the left-hand column in red. Decision chart (sign of autism)\nAfter consultation and analysis by a doctor, thecorresponding boxes in blue on the right are often found to be an appropriatetreatment or cause for the specific autism symptom. Diet and medication canoften be used to address these symptoms.\nWhen we’ve completed these initial courses of treatment,\nwe should proceed to Autism Treatment .", "pred_label": "__label__POS", "pred_score_pos": 0.8551756143569946}
{"content": "Here, we report the complete genome sequence and full methylome analysis of a newly isolated, aerobic, thermophilic, Gram-positive actinomycete, a strain of Thermoactinomyces vulgaris designated strain 2H.Copyright © 2019 Mankai et al.\nProkaryotic DNA contains three types of methylation: N6-methyladenine, N4-methylcytosine and 5-methylcytosine. The lack of tools to analyse the frequency and distribution of methylated residues in bacterial genomes has prevented a full understanding of their functions. Now, advances in DNA sequencing technology, including single-molecule, real-time sequencing and nanopore-based sequencing, have provided new opportunities for systematic detection of all three forms of methylated DNA at a genome-wide scale and offer unprecedented opportunities for achieving a more complete understanding of bacterial epigenomes. Indeed, as the number of mapped bacterial methylomes approaches 2,000, increasing evidence supports roles for methylation in regulation of gene expression,…\nThe Geobacter species evolved respiratory versatility to utilize a wide range of terminal electron acceptors. To explore this adaptive mechanism, Fe(III) citrate, hydrous ferric oxide, and fumarate were selected as electron acceptors, and the methylome and metabolome of Geobacter sulfurreducens PCA grown on each electron acceptor were investigated via third-generation, single-molecule real-time DNA sequencing and gas chromatography/time-of-flight mass spectrometry-based metabolomics, respectively. Results showed that the patterns of 4-methylcytosine (m4C) and 6-methyladenine (m6A) modification, the concentrations of fatty acids (e.g., caprylic acid, capric acid, and squalene), and the activity of antioxidant enzymes (e.g., superoxide dismutase, catalase, and glutathione reductase) were all…\nPseudorabies virus (PRV) is the causative agent of Aujeszky’s disease giving rise to significant economic losses worldwide. Many countries have implemented national programs for the eradication of this virus. In this study, long-read sequencing was used to determine the nucleotide sequence of the genome of a novel PRV strain (PRV-MdBio) isolated in Serbia.In this study, a novel PRV strain was isolated and characterized. PRV-MdBio was found to exhibit similar growth properties to those of another wild-type PRV, the strain Kaplan. Single-molecule real-time (SMRT) sequencing has revealed that the new strain differs significantly in base composition even from strain Kaplan, to…\nEthanol-type fermentation is one of three main fermentation types in the acidogenesis of anaerobic treatment systems. Non-spore-forming Ethanoligenens is as a typical genus capable of ethanol-type fermentation in mixed culture (i.e. acetate-ethanol fermentation). This genus can produce ethanol, acetate, CO2, and H2 using carbohydrates, and has application potential in anaerobic bioprocesses. Here, the complete genome sequences and methylome of Ethanoligenens harbinense strains with different autoaggregative and coaggregative abilities were obtained using the PacBio single-molecule real-time sequencing platform. The genome size of E. harbinense strains was about 2.97-3.10?Mb with 55.5% G+C content. 3020-3153 genes were annotated, most of which were methylated…\nIn 1995 a severe haemolytic-uremic syndrome (HUS) outbreak in Adelaide occurred. A recent genomic analysis of Shiga toxigenic Escherichia coli (STEC) O111:H- strains 95JB1 and 95NR1 from this outbreak found that the more virulent isolate, 95NR1, harboured two additional copies of the Shiga toxin 2 (Stx2) genes encoded within prophage regions. The structure of the Stx2-converting prophages could not be fully resolved using short-read sequence data alone and it was not clear if there were other genomic differences between 95JB1 and 95NR1. In this study we have used Pacific Biosciences (PacBio) single molecule real-time (SMRT) sequencing to characterise the genome…\nGenome-wide analysis of DNA methylation patterns using single molecule real-time DNA sequencing has boosted the number of publicly available methylomes. However, there is a lack of tools coupling methylation patterns and the corresponding methyltransferase genes. Here we demonstrate a high-throughput method for coupling methyltransferases with their respective motifs, using automated cloning and analysing the methyltransferases in vectors carrying a strain-specific cassette containing all potential target sites. To validate the method, we analyse the genomes of the thermophile Moorella thermoacetica and the mesophile Acetobacterium woodii, two acetogenic bacteria having substantially modified genomes with 12 methylation motifs and a total of 23…\nClostridium spp. can synthesize valuable chemicals and fuels by utilizing diverse waste-stream substrates, including starchy biomass, lignocellulose, and industrial waste gases. However, metabolic engineering in Clostridium spp. is challenging due to the low efficiency of gene transfer and genomic integration of entire biosynthetic pathways.We have developed a reliable gene transfer and genomic integration system for the syngas-fermenting bacterium Clostridium ljungdahlii based on the conjugal transfer of donor plasmids containing large transgene cassettes (>?5 kb) followed by the inducible activation of Himar1 transposase to promote integration. We established a conjugation protocol for the efficient generation of transconjugants using the Gram-positive origins of…\nPear ring rot disease, mainly caused by Botryosphaeria dothidea, is widespread in most pear and apple-growing regions. Mycoviruses are used for biocontrol, especially in fruit tree disease. BdCV1 (Botryosphaeria dothidea chrysovirus 1) and BdPV1 (Botryosphaeria dothidea partitivirus 1) influence the biological characteristics of B. dothidea strains. BdCV1 is a potential candidate for the control of fungal disease. Therefore, it is vital to explore interactions between B. dothidea and mycovirus to clarify the pathogenic mechanisms of B. dothidea and hypovirulence of B. dothidea in pear. A high-quality full-length genome sequence of the B. dothidea LW-Hubei isolate was obtained using Single Molecule…", "pred_label": "__label__POS", "pred_score_pos": 0.6714798212051392}
{"content": "Does top-down information about speaker age guise influence perceptual compensation for coarticulatory /u/-fronting? Georgia Zellou, Linguistics Department, University of California, Davis, Davis, California, United States Michelle Cohn, University of California, Davis, Davis, California, United States Aleese Block, UC Davis, Davis, California, United States AbstractThe current study explores whether the top-down influence of speaker age guise influences patterns of compensation for coarticulation. /u/-fronting variation in California is linked to both phonetic and social factors: /u/ in alveolar contexts is fronter than in bilabial contexts and /u/-fronting is more advanced in younger speakers. We investigate whether the apparent age of the speaker, via a guise depicting a 21-year-old woman or a 55-year-old woman, influences whether listeners compensate for coarticulation on /u/. Listeners performed a paired discrimination task of /u/ with a raised F2 (fronted) in an alveolar consonant context (/sut/), compared to non-fronted /u/ in a non-coronal context. Overall, discrimination was more veridical for the younger guise, than for the older guise, leading to the perception of more inherently fronted variants for the younger talker. Results indicate that apparent talker age may influence perception of /u/-fronting, but not only in coarticulatory contexts.\nReturn to previous page", "pred_label": "__label__POS", "pred_score_pos": 0.919620156288147}
{"content": "Abstract: Thermal transient response of internal combustion engines (ICEs) canenormously be improved by maintaining desired temperatures of coolantcirculating in engine cooling system. Thus, fuel consumption and tailpipeemissions can be significantly reduced. Computer controlled servo actuatorsare the main components of advanced automotive thermal management systems.It is evident that desired thermal conditions can be achieved when allelectrically controlled actuators function in harmony. In this paper,various control techniques are proposed for implementation on hydraulicactuated automotive cooling systems where they were never found in theliterature implemented on such systems. A neural network optimalcontrol (NNOC) and a sliding mode control (SMC) are designed and introducedto examine transient temperature tracking while minimize the smartcomponents' power consumption of thermal management system. Representativenumerical simulations are introduced to demonstrate the functionality of theproposed control schemes in accurately tracking prescribed temperatureprofiles.\nKeywords: NN optimal control, sliding mode control, temperature control, hydraulic actuated cooling system", "pred_label": "__label__POS", "pred_score_pos": 0.6752699613571167}
{"content": "Browse the document links below to better understand the DBC Concussion Protocol.\nAdapted from: Parachute. Canadian Guideline on Concussion in Sport. www.parachute.ca/concussion\nDragon Boat Canada (DBC) has developed the DBC Concussion Protocol to help guide the management of athletes who may have a suspected concussion as a result of participation in dragon boat activities.\nPurpose This protocol covers the recognition, medical diagnosis, and management of sport participants who may sustain a suspected concussion during a sport activity. It aims to ensure that athletes with a suspected concussion receive timely and appropriate care and proper management to allow them to return back to their sport safely. This protocol may not address every possible clinical scenario that can occur during sport-related activities but includes critical elements based on the latest evidence and current expert consensus. Who should use this protocol? This protocol is intended for use by all individuals who interact with athletes inside and outside the context of organized sports activity (school and non-school based), including athletes, parents, coaches, officials, teachers, trainers, and licensed healthcare professionals.\nFor a summary of the DBC Concussion Protocol please refer to the DBC Sport Concussion Pathway figure at the end of the document linked below.", "pred_label": "__label__POS", "pred_score_pos": 0.9988558292388916}
{"content": "A research team led by Dr. Stefan Strauf, who serves as the Director of the NanoPhotonics Laboratory (NPL) at Stevens Institute of Technology, has developed a new method based on holographic lithography (HL) process for producing plasmonic nanogap arrays, which are evenly placed metallic nanostructures.\nThe novel method enhances the production of plasmonic nanogap arrays, while concurrently decreasing expenditure and setup. Existing nanogap array production methods are time-consuming and expensive and have low output.\nPlasmonic nanogap arrays have small air gaps between them. By generating strongly controlled electrically fields using optical illumination, these small air gaps enable researchers to utilize the arrays in numerous applications, including ultra-sensitive sensing and photonic circuit miniaturization. Such sensors could be utilized in high-resolution microscopy or are useful in determining the presence of certain chemicals or proteins at single molecule level. Nanophotonic circuits, which can transfer large quantities of data, are critical in future-generation computing power.\nHL, an optical method that produces periodic patterns using interference patterns of laser beams, was earlier utilized for the formation of sub wavelength features. The research team upgraded the HL process by coupling the compound lattice concept and four-beam interference to produce tunable twin motive patterns into a polymer template, yielding metallic nanostructures with air gaps as low as 7 nm, which is 70 folds lesser than the blue laser light wavelengths used to create the features.\nThe researchers scaled up the usage of HL method to form gaps with yields equivalent to that of painstaking serial production methods such as focused ion beam milling or electron beam lithography. Their method is not only easier and economical but does not need a clean room. At present, the unique method attains 90% consistency in the array pattern. It realizes the rapid and economical production of large-scale superior-quality arrays.\nSource: http://www.stevens.edu", "pred_label": "__label__POS", "pred_score_pos": 0.6124927997589111}
{"content": "Abstract\nThe COVID-19 crisis has affected everyone, especially elementary school-aged children who might be too young to fully understand the sudden changes in familiar social norms as well as the unprecedented pandemic-induced educational context. This article is based on a case study that explores the perspective of the experiences of ten parents of elementary school children in French Immersion programs from different school boards during the March–June 2020 schools’ closure in Alberta. The findings show that parents had a special concern for the mental health of their children during the transition into lockdown and the ramifications of such experiences in the future as students return to school at the start of the academic year under a different climate. This includes adapting to new social norms and a certain apprehension of how school hygiene and safety measures in place will prevent a new coronavirus outbreak in schools.", "pred_label": "__label__POS", "pred_score_pos": 0.9694538116455078}
{"content": "Mr TARZIA (Hartley) (15:17): Today, I bring to the house's attention a significant local issue in my community, namely, that concerning the development of the former Magill Training Centre site. This proposed development continues to raise significant concerns within the local community, including the residents of Magill.\nI attended a recent community meeting with local residents and community leaders, including the member for Morialta, on Thursday 12 May at the Rostrevor College Pavilion, and it was at times a loud meeting, let me tell you. Many residents were rightly furious about the arrogance of the current government and its failure to address the challenges which this proposed development will present. Over 115 residents attended. I note that neither the Minister for Planning, the Minister for Transport nor the Minister for Road Safety attended the meeting. The only gentleman, in fact, who attended on behalf of the government was Mr Paul Gelston, a very capable man who I am sure will have reported to his minister the severe levels of concern in the area.\nIt was back in 2009 that the state government decided to flog off the site. Since then, since 2011 and 2012, hundreds of residents have attended an array of public meetings, putting forward various valid propositions. In the state government's complete arrogance, a ministerial DPA was released right near Christmas 2013, ignoring most of the community's feedback. Land division was submitted with the local Adelaide Hills Council in July 2015.\nIn a joint venture between Starfish Developments and Devine Limited, we have now learnt that the DAC has approved close to 400 developments at the site. I note that a number of regulated trees, even eight significant trees, are proposed to be removed. An array of issues were raised at the meeting, as you can understand, notably the inappropriate increase to near 400 homes from 250. Whilst the government has already allowed that, it does have the power to change other aspects which affect the development.\nBefore I was elected as the member for Hartley, I lobbied, and now as the member for Hartley I continue to lobby for improvements to our area to make it the best that it can be. The state government has the budget, and not only the budget but the capacity, to improve the transport solutions surrounding the site. These include cycling infrastructure and public transport infrastructure, as well as improvement of key roads and intersections that have issues now, even before the traffic of 400 dwellings hits the area.\nAs reiterated by the feedback received from local residents in the local traffic survey I recently sent out—and I thank the hundreds of residents who sent in their surveys—the increase of 400 dwellings to the site will increase traffic by thousands of movements every day. Various intersections will be negatively impacted by the development, including Glen Stuart Road and Moules Road, Moules Road and St Bernards Road, and Magill Road and Norton Summit Road. Additionally, roads such as Koongarra Avenue, Edward Street and surrounding streets will have dramatically increased volumes.\nAlong with the member for Morialta I wrote to the Minister for Transport in December 2015 to alert him to these issues. The minister must now escalate these concerns. With the state government to receive over $50 million from the sale of the site it simply cannot bank a tonne of cash from developers and ignore the concerns of my residents. The state government must implement a road traffic management plan, it must allocate funding for these problem intersections and roads. I will continue to lobby the state government on this issue, because my residents demand and deserve action to be taken.", "pred_label": "__label__POS", "pred_score_pos": 0.5617011785507202}
{"content": "The 2018 Washington State Legislature directed WSIPP to assess the impact of changes to the Juvenile Justice Act (JJA), as outlined in E2SSB 6160. To the extent possible, the study should include impacts to community safety, racial disproportionality, recidivism, state expenditures, and youth rehabilitation.\nThe 2019 Legislature amended WSIPP’s assignment to include an assessment of additional components contained in Sections 2-6 of E2SHB 1646. WSIPP must also conduct a benefit-cost analysis which includes the health impacts and recidivism effects of extending the JJA to include all offenses committed under the age of twenty-one.\nA preliminary report is due to the legislature by December 1, 2023 with a final report due December 1, 2031.\nLauren Knoth, (360) 664-9805\nView Legislation", "pred_label": "__label__POS", "pred_score_pos": 0.9860096573829651}
{"content": "Abstract\nOptical input/output interfaces between silicon-on-insulator (SOI) waveguides and optical fibers, allowing robust, costeffective and low-loss coupling of light, are fundamental functional elements in the library of silicon photonic devices. Surface grating couplers are particularly desirable as they allow wafer-scale device testing, yield improved alignment tolerances, and are compatible with state-of-the-art integration and packaging technologies. While several factors jointly contribute to the coupler performance, the grating directionality is a critical parameter for high-efficiency fiber-chip coupling. To address this issue, conventional coupler designs typically call upon comparatively complex architectures to improve light coupling efficiency. Increasing the intrinsic directionality of the grating by exploiting the blazing effects is another promising solution. In this paper, we report on our recent advances in development of low-loss grating couplers that afford excellent directionality, close to the theoretical limit of 100%. In particular, we demonstrate, by theory and experiments, several implementations of blazed grating couplers with layout features that are compatible with deepultraviolet (deep-UV) optical lithography. Devices can be advantageously implemented on various photonic platforms, including industry-specific and the offerings of publicly accessible foundries. The first experimental realizations of uniform deep-UV-compatible couplers yield losses of -2.7 dB at 1.55-µm and a 3-dB bandwidth of 62 nm. A subwavelength-index-engineered impedance matching transition is used to reduce back-reflections down to -20 dB.", "pred_label": "__label__POS", "pred_score_pos": 0.9522993564605713}
{"content": "This drug belongs to a class of drugs called DPP-4 inhibitors. A class of drugs refers to medications that work similarly. They are often used to treat similar conditions.\nNormally, hormones are released into your bloodstream as you start to eat. They cause insulin to be released into your bloodstream, which helps pick up and store the carbohydrates and sugar from the meal. Alogliptin helps these hormones to continue the release of insulin to help lower your blood sugar levels.", "pred_label": "__label__POS", "pred_score_pos": 0.6109997034072876}
{"content": "Carbon Capture and Storage Consultation Launched\nThe Department for Business, Enterprise and Regulatory Reform has launched a consultation on the future of Carbon Capture and Storage.\nA burgeoning population and consequent increase in demand for energy means that meeting global, national and regional carbon emission reduction targets will become increasingly difficult. In response, the government has proposed to build additional coal-fired power stations to meet the growing demand for energy. However, these proposals have been met with fierce criticism from environmental campaigners and leading scientists such as the President of the Royal Society, as the government’s commitment to energy supply is not presently concomitant with appropriate measures to reduce carbon emissions using carbon capture and storage technology.\nThe consultation document seeks a range of perspectives on various components of the regulation of Carbon Capture and Storage. Specifically, the document will consult on aspects of the proposed EU Directive on the Geological Storage of Carbon Dioxide and welcomes views on the principle of ‘carbon capture readiness’ for combustion plants and the regulation of Carbon Dioxide storage.\nBES members are invited to take part in the consultation response, and contributions are strongly welcomed from readers of the blog.\nLike what we stand for?\nSupport our mission and help develop the next generation of ecologists by donating to the British Ecological Society.", "pred_label": "__label__POS", "pred_score_pos": 0.5159350633621216}
{"content": "If you were lost or unsure of which direction to move in, would your rather have a map or a compass? Obviously both would be ideal. Let me suggest that a map is like a goal. It shows you where you can go but it is static. A compass points the direction. A compass is like a value. Goals can change frequently and need adjusting based on performance. Values tend to be more permanent. You may have reached your goals in 2016 and need to reset them for 2017. Values don’t need the same adjustment. If honesty and hard work were values for you in 2016, they will likely remain for 2017.\nMy suggestion for 2017 is that you review your goals and clarify your values. Look at your goals through the filter of your values. What is really important to you? Which values do you hold dearly? Which values help you to clarify everything you do? Which values do you hold so firmly that you would resign rather than violate them?\nYou need a map and a compass for 2017.", "pred_label": "__label__POS", "pred_score_pos": 0.9000101685523987}
{"content": "This education activity is intended for GPs only.\nDespite the complexities associated with this population, GPs are ideally placed to engage with patients presenting with borderline personality disorder (BPD). This education session provides an outline of how the GPs can provide effective support and treatment options for these patients.\nAt the end of this session GPs will be able to:\nPlease note: This education session will follow SAPMEA’s social distancing measures. See our COVID-19 protocols page for full information. Event details\nTuesday, September 22\n6:00pm - 08:30pm Location Name Sage Hotel - 208 South Tce, Adelaide SA 5000 Presented By Dr Cathy Ludbrook Psychiatrist\nThis event has already occured.\nIf you have any questions about it, please contact-us.", "pred_label": "__label__POS", "pred_score_pos": 0.9323548078536987}
{"content": "Abstract\nThe gastrointestinal peptide hormone gastrin is responsible for initiating the release of gastric acid in the stomach in response to the presence of food and/or humoral factors such as gastrin releasing peptide. However, it has a role in the growth and maintenance of the gastric epithelium, and has been implicated in the formation and growth of gastric cancers. Hypergastrinemia resulting from atrophic gastritis and pernicious anemia leads to hyperplasia and carcinoid formation in rats, and contributes to tumor formation in humans. Additionally, gastrin has been suspected to play a role in the formation and growth of cancers of the colon, but recent studies have instead implicated gastrin processing intermediates, such as gastrin-17-Gly, acting upon a putative, non-cholecystokinin receptor. This review summarizes the production and chemical structures of gastrin and of the processing intermediate gastrin-17-Gly, as well as their activities in the gastrointestinal tract, particularly the promotion of colon cancers.\nAll Science Journal Classification (ASJC) codes Structural Biology Biochemistry", "pred_label": "__label__POS", "pred_score_pos": 0.6537341475486755}
{"content": "Before every summer and winter, the Electric Reliability Council of Texas (ERCOT) forecasts potential electricity demand and capacity. If it appears that customer demand will exceed supply, ERCOT will initiate its Energy Emergency Alert (EEA) system.\nAlthough most of these alerts call for energy conservation, ERCOT may call a statewide power emergency that could result in \"rotating outages\"—controlled, planned service interruptions designed to ensure grid stability.\nWe anticipate that there will be sufficient generation to meet peak customer demand this summer and work closely with state and local officials to prepare for increased demand. But, we are always prepared if ERCOT must declare a power emergency.\nHere's what you can expect if ERCOT calls a power emergency:\nIf ERCOT requires CoServ to lower the demand on its system, it will result in rotating outages. These outages will only last 15-20 minutes per neighborhood.\nIf you're signed up for outage alerts, you'll receive a text or email indicating an outage at your residence. Our system automatically assesses a 2-hour estimated restoration time so we recommend visiting our outage map to ensure if you're experiencing a rotating outage. If so, you'll see a red box over our service territory with a red message indicating that mandated rotating outages are in effect. You will still receive a notification when power has been restored.\nPlease report any outages lasting longer than 25 minutes while rotating outages are in effect.\nWe want to keep the grid secure during these hot summer months. Want to do your part to conserve energy this summer? Check out our Energy Saving Tips!", "pred_label": "__label__POS", "pred_score_pos": 0.7177226543426514}
{"content": "Abstract\nThe Nougaret form of dominant stationary night blindness is linked to a G38D mutation in the rod transducin-α subunit (Tα). In this study, we have examined the mechanism of Nougaret night blindness using transgenic mice expressing TαG38D. The biochemical, electrophysiological, and vision-dependent behavioral analyses of the mouse model revealed a unique phenotype of reduced rod sensitivity, impaired activation, and slowed recovery of the phototransduction cascade. Two key deficiencies in TαG38D function, its poor ability to activate PDE6 (cGMP phosphodiesterase) and decreased GTPase activity, are found to be the major mechanisms altering visual signaling in transgenic mice. Despite these defects, rod-mediated sensitivity in heterozygous mice is not decreased to the extent seen in heterozygous Nougaret patients.\nKeywords G-proteins Night blindness Photoreceptor Phototransduction Retina Transducin ASJC Scopus subject areas Neuroscience(all)", "pred_label": "__label__POS", "pred_score_pos": 0.9777854084968567}
{"content": "Active Smoking - significantly increases the risk of infertility in both men and women.\nDue to the toxins from cigarettes, smokers are more likely to suffer from miscarriage than non-smokers. In addition, smoking increases several health risks during pregnancy, such as\npreterm labour and ectopic pregnancy,\nOvulation problems, Genetic issues, Damage to reproductive organs, Damage to eggs or premature menopause, Increased risk of cancer and increased risk of miscarriage.Smoking during fertility treatment - Smoking undermines the effects of fertility treatment.\nSmoking during pregnancy - increases the chance of pregnancy loss.", "pred_label": "__label__POS", "pred_score_pos": 0.7934108972549438}
{"content": "APAC Wholesale Voice Carrier Market share to exceed USD 7 billion in 2026 and is set to register a lucrative growth between 2020 and 2026, growing at a CAGR of over 8%. The total voice traffic across APAC exceeded 200 billion minutes in 2019.\nGet more details on this report -\nRequest Free Sample PDF\nThe APAC market is witnessing a rapid telecom shift toward HD voice calling and VoIP technologies. CSPs and telecom service providers are increasingly purchasing wholesale voice carrier services to improve revenues and mitigate financial losses, creating new avenues for market expansion. Wholesale voice carrier services have increasingly gained market traction amid the ongoing COVID-19 pandemic as subscribers are making frequent and long-duration calls. Nations, such as India, Taiwan, Malaysia, and Hong Kong, are rapidly building a strong VoIP landscape amid the ongoing pandemic, which is expected to proliferate further as work from home and remote working trends continue to rise.\nThe interconnect billing segment is set to attain a CAGR of nearly 10% by 2026. Interconnect billing solutions are becoming mainstream as telecom enterprises look for convergent billing systems to accelerate their digital transformation strategies. Convergent billing solutions enable telecom operators to eliminate the dependency on multiple legacy billing platforms and lower the total cost of ownership.\nThe leased transmission network segment accounted for over 25% of market share in 2019, attributed to the growing uptake of leased network infrastructure for VoIP call termination across multiple geographical locations in the APAC. The highly competitive nature of the telecom industry has led to an increase in the number of tier-2 and tier-3 providers, who are increasingly leasing network capacities from tier-1 operators to reduce total cost of ownership and gain profitability.\nThe traditional switching segment held around 70% of the market share in 2019. This is attributed to the high use of traditional (non-VoIP) voice calls by subscribers in developing APAC nations due to the existing legacy infrastructure. In addition, expensive cellular internet and limited choice of unlimited data packs have also refrained several subscribers from switching to VoIP, thereby increasing market share of traditional switching technologies.\nThe wholesale voice carrier market in South Korea is expected to grow significantly with robust ICT Infrastructure. The advancements in the telecom industry and commercialization of 5G network services are anticipated to support the market growth. For instance, in April 2019, KT Corporation launched its first 5G commercial network with high reliable and rapid connectivity in South Korea. The company provides voice traffic wholesale services with call termination service and interconnection support to VoIP, TDM & IPX.\nThe APAC market has witnessed the launch of several new services by key players to leverage their wholesale voice infrastructure for capitalizing on new opportunities. For instance, in December 2019, Airtel launched Airtel Wi-Fi Calling, its VoIP service, across major cities in India. Though this service, customers can benefit from enhanced calling experience at free of cost. In May 2018, Airtel launched its innovative voice platform that offers quick voice interconnects and real-time traffic analytics for global carriers across the world. The company also uses this platform for offering wholesale voice carrier services.\nSome of the leading companies operating in the market include Alepo, AT&T, Inc., Bharti Airtel Ltd., BICS SA, BT Group Plc, CenturyLink, Inc., China Telecommunications Corporation, CITIC Telecom International Holdings Limited, Comarch SA, Deutsche Telekom AG, Emirates Telecommunication Group Company PJSC (Etisalat), Globitel, IDT Corporation, NTT Corporation, Orange SA, Singapore Telecommunications Limited, Sprint (T-Mobile), Tata Communications Ltd., Telenor ASA, Telstra Corporation Ltd., Verizon Communications Inc., and Vodafone Group Plc.", "pred_label": "__label__POS", "pred_score_pos": 0.9539129734039307}
{"content": "This report highlights recent data that show, from 2007 to 2014, the preterm birth rate decreased for all age groups, and the overall birth rate for teens and women aged 20-24 years also decreased. The changing distribution of maternal age might indicate success of programs to prevent teen and unintended pregnancies.", "pred_label": "__label__POS", "pred_score_pos": 0.7925002574920654}
{"content": "People often have to queue for a busy service in many places around a city, and knowing the queue time can be helpful for making better activity plans to avoid long queues. Traditional solutions to the queue time monitoring are based on pre-deployed infrastructures, such as cameras and infrared sensors, which are costly and fail to deliver the queue time information to scattered citizens. This paper presents CrowdQTE, a mobile crowdsensing system, which utilizes the sensor-enhanced mobile devices and crowd human intelligence to monitor and provide real-time queue time information for various queuing scenarios. When people are waiting in a line, we utilize the accelerometer sensor data and\nambient contexts to automatically detect the queueing behavior and calculate the queue time. When people are not waiting in a line, it estimates the queue time based on the information reported manually by participants. We evaluate the performance of the system with a two-week and 12-person deployment using commercially-available smartphones. The results demonstrate that CrowdQTE is effective in estimating queuing status.", "pred_label": "__label__POS", "pred_score_pos": 0.9477006793022156}
{"content": "The global crisis due to the coronavirus COVID-19 in 2020 is unique in world history in its scale and impact. We need to overcome this crisis, but we also need to understand how best to help the individuals experiencing it, at all scales. We need to understand the social, mental health, and crisis management impacts…\nRead more", "pred_label": "__label__POS", "pred_score_pos": 0.685024082660675}
{"content": "AEGIS has designed and implemented the AEGIS Advanced Visualization Toolkit that is an extensible software with a wide application scope, ranging from Digital Forensic Analysis to Big Data analytics.\nThe AEGIS Advanced Visualisation Toolkit provides an extensible platform for data visualization and transformation. It is a versatile solution that can use different visualization techniques to cover the needs of IT experts as well as non-IT literate users. Via its intuitive monitoring dashboards, configurable visual representations and collaboration features, the toolkit serves as an advanced system that can support easy exploration and insight gaining from big volumes of multidimensional data.\nAEGIS Advanced Visualization Toolkit (AVT) is a set of specialized tools that can turn input data into meaningful insights through creative visualizations. Key features include:\nVisualizations of both batch data analytics and streaming analytics Processing of large and complex data sets Addressing needs of experts and non-IT experts Multiple Granularity in data representations Advanced visualisations that include dynamic real-time graphs, spatiotemporal representations (interactive maps, etc) apart from traditional charts (pie, bar, etc) Extensibility and customization for specific needs and requirements Powerful User & Access Management Business and industry Data-driven and decision-wise SMEs and large enterprises Domain-agnostic solution Digital economy Information technology, services, research and retail etc.\nTangibly validated in telecommunication, banking and manufacturing sectors and relative use-cases.\nThe Data Visualization Market is expected to have a significant growth (reach $ 19.20 Billion by 2027, based on Business Insights report) that accounts of the increasing inclination towards visual analytics, scientific visualization, and information visualization by various enterprises. The increasing adoption of data visualization in small and medium enterprises is expected to fuel the growth of the data visualization market that AEGIS AVT competes.\nThe incorporation of\ninternet of things (IoT) in all aspects of business is adding to the increase in the number of data. The rising need for decisions to be made in a short span of time requires tools to help derive analytical information from large chunks of unorganized data in a quick turn-around time. Technological advancements and flexibility in business intelligence solutions are paving the need for data integration and data analysis across varied industry sectors, this has led to the growing requirements of data visualization software for graphical representation purposes.\nThe market faces intense competition with many open source and proprietary offerings. The major differentiation factors of AVT offering are the specialized visualization needs of niche target market, the interactive visualization that supports and enhances the user’s insights and ease-of-use functionality that address the needs of experts and non-expert personnel.\nThe emerging nature of data visualization is encouraging a shift toward analytically driven businesses, where users can explore data in various forms of graphical representation, which were initially only available in tabular reports. Growth in big data, IoT and IIoT, customized reports for specific roles, ongoing training for business users, and constantly changing optimizing dashboards are the main benefits of AEGIS AVT offering. Moreover, factors, such as the shortage of skills, budget restraints and the lack of technical skills for report creation and data analysis, are highlighting the need for adoption of visualization tools, tailor-made for the specialized needs of data-driven domains.\nAEGIS AVT is designed with modularity and scalability in mind, offering multidisciplinary, intuitive and effective visualization and interaction capabilities for the end-users. Several types of programming languages and advanced visualization tools have been used to develop a platform easy-to-use for experts and non-expert users. The agnostic-domain nature of AVT allows the user to grasp information and insights from o large amount of data with ease. AVT also helps decision-makers to identify focus areas between multi-dimensional data-sets and offers effective features and tools to interpret the data.", "pred_label": "__label__POS", "pred_score_pos": 0.6183444261550903}
{"content": "The success of any test involving fluorescence (LPI, MPI, contamination, etc.) is based on having sufficiently high UV intensity and low visible light intensity for optimum contrast. All relevant NDT Codes stipulate these values.\nIt should be noted that legacy Mercury vapor lamps decrease in intensity with age, use and contamination. This results in a decrease in intensity over time. We offer Radiometers (UV Meters) and Photometers (Visible Light Meters) from Spectronics, Baugh & Weedon, Gould-Bass, UV Products, Magnaflux and our Economical House Brand.", "pred_label": "__label__POS", "pred_score_pos": 0.9995208382606506}
{"content": "Abstract\nInduced responses to insect herbivory are a common phenomenon in the plant kingdom. So far, induced responses have mostly investigated in aerial plant parts. Recently it was found that root herbivore may also elicit both local and systemic responses affecting aboveground herbivores and their natural enemies. Using broccoli (Brassica oleracea subsp. italica L.) and turnip (Brassica rapa subsp. rapa L.), two cultivated brassicaceaous plants differing in their chemistry and morphology, we analysed the local and systemic induced responses triggered by Delia radicum L. damage, JA and SA application. We also assessed whether the root induction treatments affected D. radicum larval performance. Both D. radicum damage and JA induced changes in glucosinolate and sugar content as well as affected D. radicum performance, while SA application did not. Despite the uniform chemical responses, the effect on larval performance on broccoli and turnip plantswas very different. On broccoli, JA root treatment reduced herbivore performance, whereas in turnips the same treatment enhanced it. JA- and D. radicum-induced responses followed similar patterns, which suggests that the JA signalling pathway is involved in rootinduced responses to larval feeding. Glucosinolate induction cannot fully explain the differences found in the performance of D. radicum on the different species. Changes in other resistance factors might significantly contribute to the induced resistance in these brassicaceaeous species as well.\nKeywords international", "pred_label": "__label__POS", "pred_score_pos": 0.6272717118263245}
{"content": "In this work, we present a theoretical analysis framework for relational ensemble models. We show that ensembles of collective classifiers can improve predictions for graph data by reducing errors due to variance in both learning \\emph{and} inference. In addition, we propose a relational ensemble framework that combines a relational ensemble learning approach with a relational ensemble inference approach for collective classification. This combination allows the relational ensemble to reduce errors due to variance in both learning and inference. The proposed ensemble techniques are applicable for both single and multiple graph settings. Experiments on both synthetic and real-world data demonstrate the effectiveness of the proposed framework. Finally, our experimental results support the theoretical analysis and confirm that ensemble algorithms that explicitly focus on both learning and inference processes and aim at reducing errors associated with both, are the best performers.Learn More", "pred_label": "__label__POS", "pred_score_pos": 0.825681209564209}
{"content": "Abstract\nBackground: Budgetary restrictions and shorter hospital admission times have increased demands upon nursing time leading to nurses missing or rationing care. Previous research studies involving perceptions of missed care have predominantly occurred outside of Australia. This paper reports findings from the first South Australian study to explore missed nursing care. Aim: To determine and explore nurses' perceptions of reasons for missed care within the South Australian context and across a variety of healthcare settings. Method: The survey was a collaborative venture between the Flinders University of South Australia, After Hours Nurse Staffing Work Intensity and Quality of Care project team and the Australian Nursing and Midwifery Federation, SA Branch.Electronic invitations using Survey Monkey were sent to randomly selected nurses and midwives and available online for two months. Three hundred and fifty-four nurses and midwives responded. This paper reports qualitative data from answers to the open questions. Findings: Three main reasons for missed care were determined as: competing demands that reduce time for patient care; ineffective methods for determining staffing levels; and skill mix including inadequate staff numbers. These broad issues represented participants' perceptions of missed care. Conclusion: Issues around staffing levels, skill mix and the ability to predict workload play a major role in the delivery of care. This study identified the increasing work demands on nurses/midwifes. Solutions to the rationing of care need further exploration.\nKeywords Missed care Nursing and midwifery Rationed care Skill mix Staffing", "pred_label": "__label__POS", "pred_score_pos": 0.8750156760215759}
{"content": "Electronic Thesis/Dissertation Development of a Novel DNA Break Capture Method to Study the Repair Dynamics of Topoisomerase-DNA Lesions Open Access Downloadable ContentDownload PDF\nThe last decades have seen major advances in our understanding of how DNA breaks are detected, signaled to cell-cycle checkpoints, and repaired. However, a more complete understanding of how the genomic landscape influences DNA double strand break (DSB) generation and repair is needed. To address these challenges, we have developed a new method, END-seq, to measure DSBs and DNA end-resection genome-wide at base-pair resolution in vivo. By providing a snapshot of DSBs genome-wide at a given time in a population of cells, END-seq can be utilized to study the causes and consequences of genomic instability, as well as the influence of chromatin on DNA damage response. We utilized END-seq to first determine the frequency and spectrum of restriction-enzyme, zinc-finger-nuclease, and RAG-induced DSBs, and then to study the repair dynamics of topoisomerase-induced lesions. Topoisomerase II (TOP2) relieves topological stress in DNA that arises during physiological processes by introducing double strand breaks (DSBs) via a transient intermediate that contains a covalently linked DNA-bound TOP2 molecule (TOP2cc). This structural state is normally rapidly reversible, but can be stabilized by TOP2 poisons, such as the chemotherapeutic agent Etoposide (ETO), which traps TOP2ccs on DNA. Cells are thought to remove trapped TOP2ccs primarily by proteolytic degradation followed by DNA DSB repair. However, ETO is a highly reversible drug which does not permanently inhibit the enzymatic function of TOP2. Therefore, we wanted to explore if inhibiting the proteasome created conditions where TOP2cc reversibility is favored over DSB repair upon ETO washout, and what impact suppressing proteasome mediated repair of TOP2 DNA-protein adducts would have on genome stability. Here, we show that proteasome inhibitors when used in conjunction with ETO can both potentiate and suppress the genotoxic effects of ETO, depending on what order the drugs are added to the cells. Pre-treating cells with proteasome inhibitors prevented the proteolytic processing of trapped TOP2ccs, which completely protected cells from ETO-induced genome instability and preserved cellular viability, whereas treating cells with proteasome inhibitors after ETO did not. Furthermore, by preventing RNF4-mediated ubiquitination of TOP2ccs, proteasome recruitment was suppressed, which significantly enhanced genome integrity. Despite blocking DNA damage response (DDR) signaling to ETO-induced lesions, proteasome inhibitors did not prevent the formation of TOP2-linked DSBs. Rather, by suppressing the DDR to these DNA-protein adducts, TOP2 had time to uncouple itself from the DNA following ETO washout in an error-free manner that generated fewer genotoxic lesions compared to the canonical proteasome mediated repair response. Thus, inhibiting proteasome-based repair of TOP2-DNA adducts presents a possible mechanism of resistance to topoisomerase poisons.\nLicense Relationships Items\nThumbnail Title Date Uploaded Visibility Actions File 2019-10-20 Embargo", "pred_label": "__label__POS", "pred_score_pos": 0.617328405380249}
{"content": "Traditionally, basil is appreciated mainly for its antispasmodic and digestive qualities.\nBasil is a herbaceous plant, native to India, which can reach up to 60cm. It is grown all over the world and is mainly used as an aromatic plant. In India we revere the variety known as tulsi, or sacred basil, as a sacred plant.\nThe composition of its essential oil differs according to its geographical origin. Its therapeutic efficacy is not unanimous, however it is widely used throughout the world for a large number of ailments.\nProperties of basil:\nBasil will be useful in cases of\n- difficult digestion\n- inappetence - anxiety - bloating and flatulence - intestinal parasites - acne - insomnia of nervous origin - migraines of nervous origin - tonic of the nervous system (balance, does not stimulate) Main Benefits: Acne According to Indian scientists, basil oil is effective in destroying bacteria in the skin. This would make it effective in reducing acne (externally applied to the skin). Stimulates the immune system Animal research has demonstrated that basil produces an increase of 20% in antibody production. This would explain the reputation of this plant for fighting bacteria. Intestinal parasites Basil oil would be effective in eliminating intestinal parasites. It is used for this purpose, particularly in Malaysia. Young children and pregnant women should not be treated with basil oil. Digestion and antispasmodic The use of Basilis recommended by herbalists concerns the digestive, carminative and antispasmodic properties of the Basilisk. In the form of an infusion of leaves. (3 to 4 leaves per cup of water, let infuse for a few minutes, do not exceed 3 cups per day. Precautions\nIt is therefore not advisable to use the Basilisk in an abusive and prolonged manner, especially in the form of essential oil.\nInstructions for use\nInternal use: 1 dessert spoonful per cup of hot water. Let infuse 5 to 10 minutes. Drink one to three cups a day, after meals.\nEssential oil: 3 to 5 drops in a little honey. Do not abuse the use of basil in the form of essential oil.", "pred_label": "__label__POS", "pred_score_pos": 0.7051346302032471}
{"content": "Workers’ Compensation\npayout will be. Does your employer still send you a paycheck? Does the money come from the insurance company? The following are some basics in receiving a payout while receiving medical treatment and recovering from your injury or illness.\nOpen Claims\nClaims vary by state and occupation, with some offering more of a payout and others offering less. If your claim is open, the payout received will typically depend on the severity of your injury and whether you’ll be heading back to work any time soon. Even if you can safely complete lighter duty work, for the time being, it is considered going back to work, so your payout from workers’ compensation may not be as great.\nClosed Claims\nIn most cases, injured workers do not receive any type of payout after the claim is closed. Though that is the case for most situations, there are some exceptions. First, someone who has a permanent disability could receive a pension. Second, someone with a partial permanent disability could continue to receive a weekly payout. Finally, an individual who enters a structured settlement would receive funds following the claim closure.\nTime Loss Compensation\nTemporary disability benefits are given in the form of time-loss compensation. They are paid out periodically and typically cover 66.67% of your average weekly wage. Unfortunately, it’s not the same amount you are used to receiving in a typical paycheck, but it’s a great benefit if you were injured at work. This payout may come to you twice each month, though each state varies on the frequency. You might receive a check every week, or possibly only once every month.\nLoss of Earning Power\nOne benefit of workers’ compensation is Loss of Earning Power. This is given to individuals who are injured to the point they can’t perform their typical duties, but who can perform a job in a lower-paying position. The employer would pay the employee a portion of the difference between the two positions’ wages. The payment would come through workers’ compensation.\nReceiving Assistance\nWhen you are injured on the job, you may not know where to start. When should you report your injury? How do you file a claim with the insurance company? When will you receive your payout, and for what? Contacting a workers’ compensation attorney, like a New Jersey workers’ compensation attorney, is one of the best ways to find answers to these questions. Contact an attorney today.\nThanks to Rispoli & Borneo, P.C. for their insight into how workers’ compensation pay works.", "pred_label": "__label__POS", "pred_score_pos": 0.5285696387290955}
{"content": "A survey shows that men enjoy on average 40 minutes more leisure time than women.\nFor both sexes the number one leisure activity was consuming mass media which constitutes watching TV, reading or listening to music.\nThe work-life balance study was carried out by the Office of National Statistics (ONS) in the U.K.\nOn average men spend six hours and nine minutes per week on leisure pursuits compared to five hours and 29 minutes for women.\nThe study found that women were more likely then men to perform unpaid work. Unpaid work was classified in the study as childcare, adult care, volunteering, cooking, cleaning, washing clothes, ironing, giving lifts to others, gardening and DIY.\nWomen were also found to be more sociable then men, the study found that they spent four hours and 19 minutes per week, compared with three hours and two minutes for men.\nThe study shows that on average 16 to 24-year-olds enjoy six hours of leisure time per week the same as those aged between 55-64.\nThe highest leisure time per week–seven hours and 10 minutes–was reserved for those aged 65 and over.\nWhile 25 to 34-year-olds had the least amount of leisure time at just four hours and 46 minutes per week.\nThe study revealed that those who worked in skilled-trade professions spent the least time on leisure just four hours and 34 minutes per day. This figure is compared with people in sales and customer services professions who spent the most at five hours and 21 minutes per day, report The Guardian .", "pred_label": "__label__POS", "pred_score_pos": 0.5631619691848755}
{"content": "Optical coherence tomography (OCT) has gained wide adoption in biological research and medical imaging due to its exceptional tissue penetration, 3D imaging speed and rich contrast. However, OCT plays a relatively small role in molecular and cellular imaging due to the lack of suitable biomolecular contrast agents. In particular, while the green fluorescent protein has provided revolutionary capabilities to fluorescence microscopy by connecting it to cellular functions such as gene expression, no equivalent reporter gene is currently available for OCT. Here we introduce gas vesicles, a class of naturally evolved gas-filled protein nanostructures, as genetically encodable OCT contrast agents. The ...", "pred_label": "__label__POS", "pred_score_pos": 0.9977226853370667}
{"content": "Vietnamese potato supply fails to meet demand\nVietnam has favourable condition to grow potatoes, with supply abundant in many localities. However, domestic potato processing firms are facing supply shortages.\nIn 2018, Orion Vina confectionery Company needs 18,000 tonnes of potato. To ensure local potato supply, the company has collaborated with 15,000 potato farms nationwide. However, they can only meet 40 percent of the company’s need.\nOrion Vina’s demand for potato supply will increase in the future. Specifically, in the next two years, it needs up to 22,000 and 25,000 tonnes of potato each.\nVietnam produces 350,000 tonnes of potato each year. However, only 100,000 tonnes can be used for processing. Therefore, numerous companies are importing potato for processing.\nVietnam now has only three varieties of potato suitable for processing.\nThe potato crop lasts for only three months in the winter. It is necessary to create potato varieties which are more heat-resilient to ensure potato supply throughout the year./.", "pred_label": "__label__POS", "pred_score_pos": 0.9743805527687073}
{"content": "The difference in proton radii measured with $\\mu p$ atoms and with $ep$atoms and scattering remains an unexplained puzzle. The PSI MUSE proposal is tomeasure $\\mu p$ and $e p$ scattering in the same experiment at the same time.The experiment will determine cross sections, two-photon effects, form factors,and radii independently for the two reactions, and will allow $\\mu p$ and $ep$results to be compared with reduced systematic uncertainties. These data shouldprovide the best test of lepton universality in a scattering experiment todate, about an order of magnitude improvement over previous tests. Measuringscattering with both particle polarities will allow a test of two-photonexchange at the sub-percent level, about a factor of four improvement onuncertainties and over an order of magnitude more data points than previous lowmomentum transfer determinations, and similar to the current generation ofhigher momentum transfer electron experiments. The experiment has the potentialto demonstrate whether the $\\mu p$ and $ep$ interactions are consistent ordifferent, and whether any difference results from novel physics or two-photonexchange. The uncertainties are such that if the discrepancy is real it shouldbe confirmed with $\\approx$5$\\sigma$ significance, similar to that alreadyestablished between the regular and muonic hydrogen Lamb shift.\nWe report on new p$(e,e^\\prime p)\\pi^\\circ$ measurements at the$\\Delta^{+}(1232)$ resonance at the low momentum transfer region. The mesoniccloud dynamics is predicted to be dominant and rapidly changing in thiskinematic region offering a test bed for chiral effective field theorycalculations. The new data explore the low $Q^2$ dependence of the resonantquadrupole amplitudes while extending the measurements of the Coulombquadrupole amplitude to the lowest momentum transfer ever reached. The resultsdisagree with predictions of constituent quark models and are in reasonableagreement with dynamical calculations that include pion cloud effects, chiraleffective field theory and lattice calculations. The reported measurementssuggest that improvement is required to the theoretical calculations andprovide valuable input that will allow their refinements.\nWe present an up-to-date, comprehensive summary of the rates for all types ofcompact binary coalescence sources detectable by the Initial and Advancedversions of the ground-based gravitational-wave detectors LIGO and Virgo.Astrophysical estimates for compact-binary coalescence rates depend on a numberof assumptions and unknown model parameters, and are still uncertain. The mostconfident among these estimates are the rate predictions for coalescing binaryneutron stars which are based on extrapolations from observed binary pulsars inour Galaxy. These yield a likely coalescence rate of 100 per Myr per Milky WayEquivalent Galaxy (MWEG), although the rate could plausibly range from 1 perMyr per MWEG to 1000 per Myr per MWEG. We convert coalescence rates intodetection rates based on data from the LIGO S5 and Virgo VSR2 science runs andprojected sensitivities for our Advanced detectors. Using the detectorsensitivities derived from these data, we find a likely detection rate of 0.02per year for Initial LIGO-Virgo interferometers, with a plausible range between0.0002 and 0.2 per year. The likely binary neutron-star detection rate for theAdvanced LIGO-Virgo network increases to 40 events per year, with a rangebetween 0.4 and 400 per year.", "pred_label": "__label__POS", "pred_score_pos": 0.6541661620140076}
{"content": "Zero Tolerance is an initiative led by National Disability Services in partnership with the disability sector. REAL has adopted a continuous improvement approach to ensure a Zero Tolerance culture is integral to the organisation’s practices and policies\nZero Tolerance aims to assist disability service providers to understand, implement and improve practices which safeguard the rights of people they support.\nThis evidence-based framework outlines strategies for service providers to improve prevention, early intervention and responses to abuse, neglect and violence experienced by people with disability. An expanding range of Zero Tolerance tools and resources for the disability sector are available to support broader safeguarding approaches for people with a disability.\nFormore information and resources read the\nZero Tolerance Framework orvisit https://www.nds.org.au/resources/zero-tolerance.", "pred_label": "__label__POS", "pred_score_pos": 0.9844775795936584}
{"content": "Addressing distribution equity in spatial conservation prioritization for small-scale fisheries Type:Journal Article Year of publication:2020 Date published:05/2020 Journal title:PLOS ONE Volume:15 Issue:5 Pages:e0233339\nSpatial conservation prioritization is used worldwide for designing marine protected areas (MPA) that achieve set conservation objectives with minimal impacts to marine users. People involved in small-scale fisheries (SSF) may incur negative and disproportionate impacts from implementing MPAs, yet limited available data often restricts their representation in MPA planning. Using a Philippines case study, we focus here on the systematic design of a MPA network that aims to minimize and distribute costs equitably for SSF whilst achieving representation targets for biodiversity conservation. The objectives of the study are to: (1) document a participatory mapping approach for collecting SSF data for prioritization using the local knowledge of fishers; and (2) examine how the completeness and resolution of SSF data may affect prioritization outputs in terms of biodiversity representation, spatial efficiency, and distribution equity. In the data-poor region, we conducted participatory mapping workshops with fishers in 79 communities to collect data on the spatial distribution patterns of different SSF fisheries and communities, and employed remote sensing techniques to define coastal habitats, which were targeted for inclusion in MPAs. The datasets were integrated within the decision-support tool Marxan with Zones to develop three scenarios. The SSF data incorporated in each scenario varied based on their completeness (considered all fishing methods or only dominant methods) and resolution (fishing methods itemized by community or municipality). All scenarios derived MPA plans that met representation targets with similar area coverage. The outputs, however, varied in terms of distribution equity, measured by the distribution of opportunity costs (loss of fishing grounds) across different fisheries and communities. Scenarios that did not include minority fisheries or variations between communities, led to inequitable costs. These results highlight the need to incorporate detailed data on SSF at appropriate resolutions, and how this can be achieved through participatory approaches.", "pred_label": "__label__POS", "pred_score_pos": 0.769133448600769}
{"content": "The development of treatment and preventive measures of neurological disorders is possible only if accurate estimates on incidence, prevalence, mortality, and disability are known. State-level estimates of neurological disorders in the US are not present. This study aims to determine the burden estimates of major neurological disorders.\nThis systematic analysis comprises data from the Global Burden of Disease (GBD) 2017 study. The researchers analyzed data on the incidence, mortality, prevalence, and disability-adjusted life years of major neurological disorders. 12 of these major disorders included Parkinson’s disease, epilepsy, Alzheimer’s disease, motor neuron disease, migraine, multiple sclerosis, cancers, meningitis, encephalitis, tetanus, tension-type headache, traumatic brain injury, and spinal cord injuries. The primary outcome of the study was actual numbers calculated by age-standardized rates.\nThe results suggested that stroke (3.58), Alzheimer’s disease (2.55), and migraine (2.40) were the most burdensome neurological disorders in the US. It was also found that the burden of all neurological disorders increased from 1990 to 2017. The only exceptions to this trend were traumatic brain injury incidence, spinal cord injury prevalence, spinal cord injury prevalence, and deaths.\nThe research concluded that there was a substantial burden of neurological disorders in the US, with the burden being the most significant for stroke, Alzheimer’s disease, and migraine.", "pred_label": "__label__POS", "pred_score_pos": 0.5339068174362183}
{"content": "It may sound obvious but caring for our feet often slips our mind and can put us at risk of having a fall.\nDid you know that good vision helps prevent us from having a fall?\nOur vision plays a key role in maintaining our balance and identifying hazards in our environment, so we can navigate around them. Continue reading “Healthy Eyes for Falls Prevention”", "pred_label": "__label__POS", "pred_score_pos": 0.9565181136131287}
{"content": "Legal Ramifications of Elderly Cohabitation: Necessity for Recognition of Its Implications by Family Psychotherapists\nSUMMARY. This paper views cohabitation among the elderly from a legal perspective and presents realities of which many family practitioners may not be aware. Five key areas that the therapist and his or her clients should recognize will provide a foundation for under-\nstandin~ the responsibilities and potential legacy of the cohabitation. By deSign, this paper should contribute to the avoidance of the costly and unpleasant resort to legal suit. An appended list of 28 legally-oriented items should be considered at the outset of cohabitation.", "pred_label": "__label__POS", "pred_score_pos": 0.8617302775382996}
{"content": "I'm so excited to be sharing a different kind of post with you today! Over the last few months, I've been working really hard on my health and fitness routine. I preface this by saying I am not a doctor, dietitian, etc., but what I've been doing the last few months - eating right, working out five or more times a week - has really made me feel better.\nLike many of us, come the new year, I always make a resolution to work out more. To be honest, I usually always fail. Back in my 20's I could eat whatever I wanted, not go to the gym, and I it didn't affect me\nat all. I remember someone saying to me, \"Just wait until you turn 30.\" Yeah, right I thought (insert eye-roll), but sadly, they were right. I definitely saw a change in my energy, metabolism and the fact that I couldn't have all those carbs I love so much without it being visible. I realized quickly I needed to start working out, and be more aware of what I eat. Even after I turned 30 though, I kept dipping my foot in, but not fully jumping in...until this year.\nI think what gave me the extra push at the beginning of 2019 was that one of my favorite workout classes, The Bar Method, was having a 'New Year New You' (or something like that) challenge. The challenge was to do 20 classes in 30 days. Phew, it's a lot, and if you've ever done a barre class before, you know how hard they are. I thought to myself, I\nwantto do this, I cando this. You know what, I did(!!!), and since then, I've signed up for and completed two more challenges.\nThe workout is a mix of yoga, pilates, and ballet. Not only is it great for strengthening and creating long lean muscles, but they focus a lot on stretching too, which is great for my arthritis. If you're new around here, I shared more about my journey with arthritis in a post a few years ago, which you can read here. I've seen my flexibility and mobility increase, and just have felt stronger. This is definitely not a sponsored post, although I'd happily welcome it (pst, Bar Method!). I truly just have found a workout that is perfect for me. I feel more confident, and I'm not talking confident in my appearance (although I definitely can see a difference). I'm more confident in my capabilities, myself, my work ethic, my commitment and my sense of community. When you work from home, it's nice to have that interaction at a gym/studio, and the ladies (and a few men), that go to Bar are great. The instructors at the Montrose studio are amazing, fun, and so encouraging, which is what keeps me coming back. An added bonus, it's perfect for all ages and skill levels!\nI also mix in spinning/biking on our Peloton at home, and when it's not 100 degrees, my favorite form of exercise is walking. I could walk for forever if it was possible! It's true what they say, you just feel better after working out.\nI found these great monthly exercise calendars (see below) from a fellow blogger, and they've really helped me hold myself accountable to getting in those five days a week. I'd love to hear what your favorite workout is and why. Be sure to stay tuned for health and wellness posts, too!", "pred_label": "__label__POS", "pred_score_pos": 0.6740648150444031}
{"content": "Each journey in our personal and professional lives will take us through the highs and the lows. If we only decide to celebrate once we get to the mountain top, then we’re not realizing the beauty in the journey itself. The joy of reaching the mountain top is a feat in itself. To make our lives more happy and meaningful, we should take the good with the bad.\nI remember a time when a speaker at an event I attended many years ago said “\nPeople are like plants: we need both sun and water to grow .“", "pred_label": "__label__POS", "pred_score_pos": 0.8472304344177246}
{"content": "Global Societies Journal The Battle for Development: Economic Growth versus Institutions, Fighting for Long-term Sustainable Outcomes Author(s): Brown, Hannah K. et al. Abstract\nThe globalization process, accelerated through technology proliferation, has “brought about profound changes in the international context [and] could have far-reaching implications for development” according to Deepak Nayyar. He argues a myth exists advocating the spread of globalization and global economic wealth convergence; however, globalization is uneven and a sharp divide between rich and poor countries persists. For example, during the 1980s and 1990s poverty increased in most Latin American, Caribbean, and Sub-Saharan African countries. However, not all developing nations have stagnated, some have experienced high sustained economic growth rates. Both China and Botswana have been hailed as such examples in the developing world while some of their neighbors, notably Mongolia and Zimbabwe, have had more trouble. This begs the question, why have some developing countries achieved development while others have not? To begin to address this question, one must look at various development models and case studies. Before trying to achieve rapid economic growth, it is critical that nations have strong institutions embedded within state infrastructure to ensure long-term sustainable development.", "pred_label": "__label__POS", "pred_score_pos": 0.8973339796066284}
{"content": "I dreamed I was walking with a group of 5 females, we were good friends and laughing while on a short weekend getaway. I felt soooooo happy. I woke up smiling.\nI think I know what this one means, but please interpret. Thank you Mary Ann\nHi Mary Ann,\nWhat a pleasant dream! While we often think that our dreams are prophetic as in foretelling the coming future, it isn't always the case. However, they do reflect our fears and desires.\nThe symbols in your dream (five females, good friends, laughing, weekend getaway, feeling happy) are all very positive. It will be a good thing for you to engage all of your five senses in relishing life (for example, taking care to appreciate the fragrance of a flower, inhale fresh air, gaze at beautiful things, savor flavors). Dreaming of friends often signals coming positive times or news.\nDreaming of a getaway tells you to do just that: take time out for a mini-escape from your waking life stresses. Your mind is telling you what you need, what your body is yearning for.\nLaughing in your dream underscores your need to be unburdened from waking life stresses.\nPerhaps you yearn for trusted, comfortable friendships. If you do have them in your waking life, be sure not to take them for granted. Set aside time to nurture them. This is not a luxury for you but a necessity, as serious as taking medicine for an ailment.\nPositive social connections, laughter, getaways are incredibly healing. But don't wait until you are feeling beaten down before you reach for the elixir. An ounce of prevention is worth a pound of cure.", "pred_label": "__label__POS", "pred_score_pos": 0.7216752767562866}
{"content": "Abstract\nAlopecia areata (AA) is the second most common cause of hair loss. It is crucial for the clinician to differentiate AA from other types of hair loss as it differs in prognosis and treatment. The diagnosis of AA can be made clinically; however, there are many nuances making an exact diagnosis challenging. This paper describes the differential diagnoses of both scarring and non-scarring hair loss that may mimic AA. It also highlights the diagnostic tests and pertinent findings that help distinguish AA from other types of hair loss.\nKeywords alopecia areata alopecia totalis alopecia universalis dermoscopy diagnosis trichoscopy ASJC Scopus subject areas Dermatology", "pred_label": "__label__POS", "pred_score_pos": 0.5437242388725281}
{"content": "Edited by Kerry Mallam\nYou can also purchase the digital version of this publication.\nPicture Books and Beyond examines a wide selection of picture books, graphics novels, films, e-picture books and apps that reflects the diversity of various evolving cultural artefacts, and their opportunities for education and delight. It aligns closely with the goals and directions of the Australian Curriculum: English, and considers the potential of texts for enabling students to respond critically and creatively. It also highlights links to other curricula, general capabilities, and cross-curriculum priorities.\nChapters are generously illustrated incorporating a range of relevant images from the picture books and other texts discussed by the contributors. Each chapter offers readings and interpretive opportunities through the complex interplay of words and images, narrative strategies, digital interactivity, or filmic adaptation in the sample texts. At the end of each chapter a list of 'Additional texts' is intended to lead readers to other useful examples that relate to the topics discussed.", "pred_label": "__label__POS", "pred_score_pos": 0.8529503345489502}
{"content": "In 2018, the European Commission adopted criteria to assess whether a biocide or pesticide is an endocrine disruptor. A guidance document was written on how to do this in practice. In this webinar, FREIA partner Julie Boberg (Technical University of Denmark) will explain the process of ED identification, using butylparaben as an example.\nButylparaben is often used in cosmetics to prevent microbial growth. It is on the candidate list of substances of very high concern of the European Chemicals Agency for its endocrine disrupting properties. Not only will Ms Boberg show that butylparaben has more negative effects on reproduction than previously thought, but she will also explain how this substance is a great example of how current criteria and EDC identification tools may also be suitable for other chemical regulations. This webinar is organised by the FREIA project, with support from the Health and Environment Alliance (HEAL). Participation is free. For more details, please contact info@freiaproject.eu", "pred_label": "__label__POS", "pred_score_pos": 0.8127717971801758}
{"content": "The power of self reflection is profound. Without checking back deep within ourselves and listening to what is happening within, we cannot grow and prosper. We might remain slaves to what we have been taught to feel, to sense, to think. Yet we are slaves without shackles. Nothing is truly bounding us, but..\nthe limitations of our mind. In our journey to explore the depth of our soul, we are never alone. While some may seek to stop us, many seek to guide us on our path. Authors, priests, gurus, therapist, friends; their consult may work or it may come unsolicited and irritate us with irrelevancy. However, one guide holds the wisdom to deliver accurate, remarkably authentic and pure advice. If we are committed to liberating our soul and opening the door for development and growth, we must pay heed to the guidance of mankind's oldest friend; the horse.\nHorses have incredible powers to teach people about self imposed limitations, unproductive thought patterns and self destructive tendencies that prohibit them from reaching full potential. And yet the majority of people uses horses as a tool for self advancement in a more superficial nature. We seek success, monetary gain, approval, excitement and use horses to gain access to those things. In the process, the horses are gagged; after all, their voices would only hinder our quest for the things we think we need. Sometimes we silence them gently and with empathy. Other times our frustration steers us toward impatience and violence. No matter our approach, whenever we silence our horse, we take away our source for genuine, unbiased feedback; their freedom to respond to us the way they see fit.\nLast week I finalized my certification with EAGALA, a world leader in Equine Assisted Psychotherapy. Their concept is simple, yet profoundly effective; bring horses and people together without restrains, allow the people and the horses to interact with each other and ask the people to reflect on their experience. While learning about the method, I participated in sessions with the horses. The experience was humbling. After years as a business consultant, I believed the reviews and coaching I received, had made me pretty aware of my thought patterns and proclivities. Yet the horses demonstrated my ignorance, and allowed me discover my authentic self. They showed me how my lingering perfectionism hinders me in finding peace. They demonstrated how I still struggle with conformity versus following my own heart. They uncovered how deep inside I am not satisfied with working all by myself and miss working in a team. They showed me how I am still trying to make my father, who passed away 10 years ago, happy by working as hard as I can so I'll never fail him. They showed me how much more I can do with gentleness instead of force. And they taught me much much more.\nI want other people to experience this exceptional wisdom. I want people to not only uncover their own potential, but also the potential of the horse. The potential that is right there, in our barn, in our pasture, waiting for an opportunity to not be bridled, not be disciplined, not be steered around a dressage test. That potential that awaits us at the end of our lead rope and is unleashed the minute we untie the rope halter's knot.\nWe horses owners are lucky to have the most insightful, instinctual psychiatrists waiting for us to be ready to listen. Our horses are forever remaining in readiness for us to be become aware of how their peaceful wisdom can guide us back to ourselves, to our equilibrium, to quietude. My journey has begun. I can't wait to see where it leads me next.\nHours\nM-T: 10am - 3pm\nTelephone\n+ 1 864.906.7576\nmonique@equineflow.com\n\"We cannot direct the wind, but we can adjust the sails.\" - Dolly Parton", "pred_label": "__label__POS", "pred_score_pos": 0.9800246953964233}
{"content": "Palomo I, Willemen L, Drakou E, Burkhard B, Crossman N, Bellamy C, Burkhard K, Campagne CS, Dangol A, Franke J, Kulczyk S, Le Clec'h S, Malak DA, Muñoz L, Narusevicius V, Ottoy S, Roelens J, Sing L, Thomas A, Van Meerbeek K, Verweij P (2018) . One Ecosystem 3: e20713.\nAbstract\nEcosystem services (ES) mapping is becoming mainstream in many sustainability assessments, but its impact on real world decision-making is still limited. Robustness, end-user relevance and transparency have been identified as key attributes needed for effective ES mapping. However, these requirements are not always met due to multiple challenges, referred to here as bottlenecks, that scientists, practitioners, policy makers and users from other public and private sectors encounter along the mapping process.\nNew information\nA selection of commonly encountered ES mapping bottlenecks that relate to seven themes: i) map-maker map-user interaction; ii) nomenclature and ontologies; iii) skills and background; iv) data and maps availability; v) methods-selection; vi) technical difficulties; and vii) over-simplification of mapping process/output. The authors synthesise the variety of solutions already applied by map-makers and map-users to mitigate or cope with these bottlenecks and discuss the emerging trade-offs amongst different solutions. Tackling the bottlenecks described here is a crucial first step towards more effective ES mapping, which can in turn ensure the adequate impact of ES mapping in decision-making.", "pred_label": "__label__POS", "pred_score_pos": 0.8803074955940247}
{"content": "Hawaii news now reports that the son of a country music singer Craig Morgan has died in a tragic boating accident. The 19-year-old boy, Jerry Greer, had been tubing with a friend when the incident occurred. The friend survived the accident, but Greer did not. Additional details surrounding the fatality have not been released.\nWith its idyllic climate and being surrounded by water, boating and other water sports are extremely popular in Hawaii. However, due to its popularity, boat operators need to use care to avoid accidents. This includes taking boating safety courses such as the one provided by the Department of Land and Natural Resources. According to the U.S. Coast Guard, roughly 7000 boating accidents are reported each year, and almost 1000 fatalities.\nAdditional safety measures include ensuring that you have life jackets, avoiding reckless or distracted boating, not boating under the influence, and staying out of hazardous water ways. Despite taking precautions, fatalities may still occur.\nFor more information, or if you or a loved one has been in a boating accident, please contact the experienced Hawaii personal injury lawyers at Bostwick & Peterson, LLP for an immediate consultation.", "pred_label": "__label__POS", "pred_score_pos": 0.9980725049972534}
{"content": "Selecta Biosciences and Asklepios BioPharmaceutical today announced the U.S. Food and Drug Administration (FDA) has granted Rare Pediatric Disease Designation to MMA-101 for the treatment of isolated methylmalonic acidemia (MMA) due to methylmalonyl-CoA mutase (MMUT) gene mutations. The FDA grants Rare Pediatric Disease Designation to incentivize development of new treatments for serious and life-threatening diseases that primarily affect children ages 18 years or younger with fewer than 200,000 people affected in the U.S. The Rare Pediatric Disease designation program allows for a sponsor who receives an approval for a product to potentially qualify for a voucher that can be redeemed to receive a priority review of a subsequent marketing application for a different product.\n“This Rare Pediatric Disease designation from the FDA highlights the significant unmet medical need that Selecta and AskBio are seeking to address with MMA-101 for this rare metabolic disorder, When used with AAV gene therapy vectors, Selecta’s ImmTOR aims to inhibit the immune response to the AAV vector, potentially allowing re-dosing of gene therapies. Ongoing clinical programs will focus on evaluating product candidate performance in patients who may have been underdosed or those who may lose transgene expression over time. We’re honored to receive this recognition and look forward to advancing this program in hopes of helping young patients affected by MMA and their families.” Carsten Brunn, Ph.D., chief executive officer of Selecta Biosciences Said: “MMA is a serious and potentially life-threatening inherited metabolic disorder that presents in patients from newborns to adulthood, AskBio is committed to delivering transformative genetic medicines for rare diseases like this one, and the Rare Pediatric Disease designation helps us continue development of MMA-101.” Sheila Mikhail, J.D., CEO and co-founder of AskBio Said:\nAskBio and Selecta expect to initiate a Phase 1 clinical trial of MMA-101 and ImmTOR for patients with MMA in 1H 2021.\nAbout Methylmalonic Acidemia\nMethylmalonic acidemia (MMA) is a rare monogenic disorder in which the body cannot break down certain proteins and fats. This metabolic disease may lead to hyperammonemia and is associated with long-term complications including feeding problems, intellectual disability, chronic kidney disease and inflammation of the pancreas. Symptoms of MMA usually appear in early infancy and vary from mild to life-threatening. Without treatment, this disorder can lead to coma and in some cases death.", "pred_label": "__label__POS", "pred_score_pos": 0.724064826965332}
{"content": "當前土壤酸化加劇，而土壤酸化對作物養分積累和分配的影響仍不十分清楚。研究揭示土壤酸化對土壤養分有效性和植物吸收、積累、分配養分的影響，為酸化土壤治理尤其是養分高效利用提供依據。采用盆栽試驗，以酸性紅壤（pH 5.05）、櫻桃番茄(Lycopersivon esculentum Mill) 為試驗材料，采用檸檬酸-磷酸氫二鈉緩沖液和碳酸鈉-碳酸氫鈉緩沖液調節土壤pH，使土壤pH下調至4.0，5.0及上調至6.0和7.0，試驗共4個處理，每處理5個重復。結果表明，通過緩沖液調節，實測土壤pH為4.35、4.92、5.89、6.85，分別下調0.70、0.13及上調0.84和1.80個pH單位。土壤酸化顯著降低櫻桃番茄葉面積、生物量尤其是根系生物量，降低植株根冠比；土壤酸化嚴重抑制氮、磷、鉀、鎂、鐵在番茄根系的累積，而促進鐵、錳在莖稈和鈣、鎂在葉片的累積分配，使根系氮、磷、鉀、鈣、鎂、鐵積累量顯著降低，莖稈積累氮、鉀、鐵、錳較多，葉片積累磷、鈣、鎂較多，特別是植株各部位錳含量顯著提高。由此說明，根系是番茄植株受土壤酸化抑制最嚴重、最敏感的部位，并因此導致多數養分被根系吸收、遷移受阻而積累顯著下降。\nSoil acidification is currently increasing, but how does soil acidification affect nutrients distribution and accumulation in plant is still not clear. Effects of soil acidification or pH on soil nutrient availability, nutrients concentration and accumulation, migration and distribution in plant were measured, with aim to utilize acidic soil and its nutrients efficiently. Pot experiment was conducted with acidic red soil (pH 5.05) and Cherry tomatoes (Lycopersivon esculentum Mill) as test materials, the soil pH was adjusted with citric acid-sodium hydrogen phosphate buffer and sodium carbonate-sodium bicarbonate buffer to adjust soil pH to 4.0,5.0,6.0 and 7.0. There were 4 treatments in total, with 5 replicates for each treatment. The result shows that measured soil pH were 4.35, 4.92, 5.89, 6.85, respectively, adjusted down by 0.70, 0.13 and increased by 0.84 and 1.80 pH. Soil acidification significantly reduced the leaf area and biomass of Cherry tomato, especially the root biomass,and root to shoot ratio. Soil acidification severely inhibited the accumulation of N, P, K, Mg and Fe in roots, promoted the accumulation and distribution of Fe and Mn in stem, and Ca and Mg in leaves. Significantly decreased N, P, K, Ca, Mg and Fe accumulations and its proportion to total in root, with more N, K, Fe and Mn accumulated in stems, more P, Ca and Mg accumulated in leaves, particularly raised all whole plant Mn concentrations significantly. It concluded that the root was the most severe and sensitive part of whole tomato plant inhibited by soil acidification, as a result, most nutrients were absorbed by the roots, migration were blocked, and accumulation was significantly reduced.", "pred_label": "__label__POS", "pred_score_pos": 0.9114168882369995}
{"content": "This study was initiated to investigate the economical impact of vaccination against tropical theileriosis in cattle in Cappadocia in Turkey. A total of 554 vaccinated and non-vaccinated animals were monitored for Theileria annulata infection using microscopic examination serology by measuring the antibody response of the animals by the indirect immunofluorescence antibody test (IFAT). The prevalence of T annulata infection, morbidity and mortality were significantly higher in unvaccinated than in vaccinated cattle, whereas the seropositivity was significantly lower in the unvaccinated group. Acute tropical theileriosis cases were diagnosed in 156 of 554 (27.61%) cattle, and 86 of 156 (56.21%) died from the disease. The total economic losses because of tropical theileriosis were estimated at US$598,133 for 2 years.", "pred_label": "__label__POS", "pred_score_pos": 0.6536272764205933}
{"content": "Title Date of Award\n2017\nFirst Advisor\nAaron Williams\nSecond Advisor\nJackson Liscombe\nThird Advisor\nAmanda Landi\nAbstract\nRecent years have seen a wide-spread adoption of conversational interfaces. Conversational agents, commonly referred to as chatbots, are programs that can exhibit human-like conversational behavior. They are taking over messaging platforms, redefining marketing and replacing human workers in customer support centers. However, there exists healthy skepticism on whether chatbots can deliver on what has been promised. This thesis aims to cover the main points of mismatch between the actual technology and its public perception by providing historical context for understanding modern chatbots. We consult Turing's ground-laying work to figure out why people were interested in talking to computers in the first place, highlight the role of dialogue systems in the general field of AI research and follow conversational agents on their journey for recognition, funding and purpose. We apply our findings by analyzing potential applications for chatbots within the Simon’s Rock campus and community.\nRecommended Citation\nKotov, Maksim, \"Chatting with Bots: A Quick Survey of Conversational Agents And Their Appropriate Applications\" (2017).\nSenior Theses. 1163. https://digitalcommons.bard.edu/sr-theses/1163\nSimon's Rock students and employees can log in from off-campus by clicking on the Off-campus Download button and entering their Simon's Rock username and password.", "pred_label": "__label__POS", "pred_score_pos": 0.9078173637390137}
{"content": "Abstract\nPurpose: This phase I study was conducted to determine the dose-limiting toxicities (DLT) and maximum tolerated dose (MTD) for the combination of bortezomib and alvocidib in patients with B-cell malignancies (multiple myeloma, indolent lymphoma, Waldenstrom macroglobulinemia, and mantle cell lymphoma). Experimental Design: Patients received bortezomib (intravenous push), followed by alvocidib (1-hour infusion), on days 1, 4, 8, and 11 of a 21-day treatment cycle. Patients experiencing responses or stable disease continued on treatment at the investigator's discretion. A standard 3+3 dose-escalation design was used to identify the MTD based on DLTs, and pharmacokinetic and pharmacodynamic studies were conducted. Results: A total of 44 patients were enrolled, with 39 patients assessed for response. The MTD was established as 1.3 mg/m\n2 for bortezomib and 40 mg/m 2 for alvocidib. The most common hematologic toxicities included leukopenia, lymphopenia, neutropenia, and thrombocytopenia. The most common nonhematologic toxicities included diarrhea, fatigue, and sensory neuropathy. Three complete remissions (8%) and 10 partial remissions (26%) were observed for a total response rate of 33%. Pharmacokinetic findings with the current dosing regimen were consistent with the comparable literature and the hybrid dosing regimen. Pharmacodynamic study results did not correlate with clinical responses. Conclusions: The combination of bortezomib and alvocidib is tolerable, and an MTD has been established for this schedule. The regimen appears to be efficacious in patients with relapsed/refractory multiple myeloma or indolent non-Hodgkin lymphoma. As the nonhybrid regimen is less cumbersome than the previous hybrid dosing schedule regimen, the current schedule is recommended for successor studies. ASJC Scopus subject areas Oncology Cancer Research", "pred_label": "__label__POS", "pred_score_pos": 0.7394181489944458}
{"content": "Collateral Repair Project (CRP) is pleased to announce that we have been selected to receive an award of $25,000 from the U.S. Embassy in Jordan through the Julia Taft Refugee Fund.\nThe Fund, awarded by the U.S. Department of State’s Bureau of Population, Refugees and Migration, aims to address gaps in refugee protection and assistance through the implementation of sustainable programs. Julia Taft served as the Assistant Secretary of State for the Bureau of Population, Refugees, and Migration from 1997 to 2001.\nWith this award, CRP will expand its programs for women’s livelihoods over the coming year. CRP will offer beauty and salon skills training to 60 women. Additionally, 12 members of the Hope Workshop will receive special training in garment making. Over the coming year, we will provide a 36-hour module of business skills training for 120 women enrolled in both Hope Workshop and Beauty School. These programs help women from refugee communities to potentially create new income for their families.\nHope Workshop is a craft collective that allows women to express their creativity while also earning extra income for their families. Beauty School is a comprehensive course of salon skills. Held in the women-only section of our community center in Hashemi Shamali, both Hope Workshop and Beauty School are safe spaces for women to work and learn together.\nWe look forward to sharing success stories from this women’s livelihoods initiative at CRP in the coming months, and we express our sincere gratitude to the U.S. Department of State for this opportunity.\nCRP, established in 2006, is a grassroots organization in Amman, Jordan providing needed assistance to refugees. CRP runs two community centers and is solely dependent on donor support. If you are interested in being a donor, please contact donors@collateralrepairproject.org.", "pred_label": "__label__POS", "pred_score_pos": 0.9170399308204651}
{"content": "Thursday, August 15, 2019\nAbstract\nIn a two-year period, 1885-86, over 168 communities in America forcibly expelled Chinese residents from their midst. This essay, inspired by historian Beth Lew-Williams's book, THE CHINESE MUST GO, investigates the nineteenth-century purges of Chinese residents that occurred throughout the American west. I make three arguments. First, these acts of racial and political terror complicate our understanding of racial violence in America. Many of the actions were denounced, but they were also surprisingly effective in forcing business and political leaders to support the indefinite suspension of Chinese migration. Perpetrators faced almost no legal repercussions, and unlike for freed persons, racial violence didn't lead to significant legislation to help the Chinese. Judicial rulings were mixed: the recognition of birthright citizenship was a high point, but rulings that codified exclusion as a national policy and recycled theories of cultural incompatibility proved problematic. Second, this wave of domestic terror complicates our view of popular constitutionalism. A wide range of anti-Chinese mobilization — from aggressive boycotts to lynchings and beatings to purges accomplished without a single shot fired — were justified by perpetrators according to America's higher law tradition. It should trouble us that these methods were so successful. Third, moving in a normative direction, I urge a new way of talking about inequality where we don't merely stress reasons to oppose inequality but instead create a typology of different forms of inequality. This will allow us to better appreciate the clusters of harms that certain historical forms of inequality create, along with the clusters of reasons to oppose a particular type of inequality. For instance, the racial purges undertaken against the Chinese shared characteristics with other forms of inequality, especially lynching, detention, and the use of symbols or signage to convey a message of status inequality.\nKJ\nhttps://lawprofessors.typepad.com/immigration/2019/08/immigration-article-of-the-day-racial-purges-by-robert-l-tsai.html", "pred_label": "__label__POS", "pred_score_pos": 0.8575858473777771}
{"content": "Because of the many benefits of breast milk, working mothers may go to great lengths to ensure that their baby is fed breast milk when they are away. To offer adequate support to nursing moms and to ensure that the nutrients of the breast milk are protected, nannies must be knowledgeable about handling, storing, defrosting and serving breast milk.\nAccording to La Leche League International, properly expressed milk can be stored at room temperature for up to 6 hours (4 being ideal) and it can be refrigerated for up to 8 days (72 hours being ideal). If it is not going to be used within that time frame, it should be poured into a clean, BPA free plastic nursing bag or glass or hard plastic container, sealed and placed into the freezer.\nIf the freezer is part of the refrigerator with a separate door, the milk should be used within 3 to 6 months. Milk stored in a separate deep freezer can be stored for six to twelve months. La Leche League International recommends placing the milk in the back of the freezer where the temperature is most consistent.\nFrozen expressed milk should be thawed by placing it in the refrigerator overnight or by running it under cool water. Increase the temperature of the water to get the milk warm enough for feeding. Alternatively, containers of frozen breast milk can be thawed by placing them into a cup or bowl that has been filled with heated water. Thawed milk should be used within 24 hours and should not be refrozen.\nLa Leche League International states there is no research about whether freshly expressed milk left unfinished at room temperature should be discarded, or can be saved for a short time, perhaps up to one hour. Nannies should consult with the parents regarding the feeding of unfinished breast milk.\nAnd while you can add freshly expressed breast milk to refrigerated or frozen milk expressed earlier in the same day, the Mayo Clinic advises that you should thoroughly cool the freshly expressed breast milk in the refrigerator or in a cooler with ice packs before adding it to previously chilled or frozen milk. Warm breast milk should also not be added to frozen breast milk as warm breast milk will cause the frozen breast milk to partially thaw.\nAvoid using a microwave oven to warm expressed breast milk. Microwave heating may cause some hot spots in the milk that can burn the baby’s mouth. Microwave heating may also destroy some beneficial properties of the milk.", "pred_label": "__label__POS", "pred_score_pos": 0.8570257425308228}
{"content": "This review evaluates the potential of delayed cord-clamping for improving iron status and reducing anaemia in term infants and for increasing the risk of polycythaemia and hyperbilirubinaemia. We applied a strict search protocol to identify controlled trials of early vs late cord-clamping. Four trials from developing and four from industrialised countries were finally assessed. Two of the four studies from developing countries found a significant difference in infant haemoglobin levels at 2-3 months of age in favour of delayed cord-clamping. This difference was more marked when mothers were anaemic. Three of four studies from industrialised countries showed a significant difference in haematocrit levels in favour of delayed clamping. Although meta-analysis showed an increased risk for hyperbilirubinaemia of 12%, no studies reported the need to apply phototherapy or perform exchange transfusion. We conclude that delayed cord-clamping in term infants, especially those with anaemic mothers, increases haemoglobin concentration in infants at 2-3 months of age and reduces the risk of anaemia, without an associated increased risk of perinatal complications. In developing countries where fetal anaemia is common, the advantages of delayed cord-clamping might be especially beneficial.", "pred_label": "__label__POS", "pred_score_pos": 0.5447050333023071}
{"content": "Abstract\nFalse claims are a key feature of confabulation, delusion, and anosognosia. In this paper we consider the role of motivational factors in such claims. We review motivational accounts of each symptom and consider the evidence adduced in support of these accounts. In our view the evidence is strongly suggestive of a role for motivational factors in each domain. Before concluding, we widen the focus by outlining a tentative general taxonomy of false claims, including false claims that occur in clinical settings as well as more garden-variety false claims, and incorporating both motivational and nonmotivational approaches to explaining such claims.\nKeywords Anosognosia Confabulation Delusion Motivational processes", "pred_label": "__label__POS", "pred_score_pos": 0.9122720956802368}
{"content": "This is one of those arguments which we love to argue about. This duality, of yes versus no is very reflective of our culture and our love for binary oppositions. Last year, Prime Minister Joseph Muscat stated that work was being done with regards to building a tunnel between Malta and Gozo and it could be up and running within seven years (now six).\nSo what are the arguments in favour of a tunnel? For one,\ntravel time will be reduced, as people travelling from Malta to Gozo and vice versa will no longer need to board a ferry. This positively impacts those who travel with it on a regular basis for work, or else to study at the University of Malta. This will undoubtedly make things easier for Gozitans studying in Malta as there would be no need to rent an apartment, due to the hassle of travelling back to Gozo. Apart from this, the waiting time in traffic leading up to the ferry will be a thing of the past.\nWith a tunnel, Gozo becomes more\naccessible to the Maltese and our tourists. This would undoubtedly increase activity in Gozo and contribute to its economy. Just think about the increase in occupancy rates for Gozitan restaurants and hotels. Even tourists who rent a car will have it easier to visit Malta’s sister island.\nOn the other hand, we have those who are strongly against the idea of adjoining Malta and Gozo via a tunnel. This side argues that making it more accessible will basically\ntransition Gozo into an extension of Malta, making it lose its identity. Gozo is a quiet place with a certain appeal, and those against the tunnel argue that it will become similar to Malta with its high-rise buildings and its hustle and bustle.\nA tunnel will make the Gozo experience less attractive since the ferry is part of the trip. It will no longer be deemed as a short holiday for the Maltese, since it becomes accessible via a simple drive.\nGozo is undoubtedly facing change, an ageing population and the younger generation seeking pastures in Malta to satisfy their career ambitions.\nIs the tunnel the right step forward in Gozo’s development?", "pred_label": "__label__POS", "pred_score_pos": 0.6890184879302979}
{"content": "By David Gauntlett\nIn Making is Connecting, David Gauntlett argues that via making issues, humans have interaction with the area and create connections with one another. either on-line and offline, we see that folks intend to make their mark at the international, and to make connections.\nthrough the prior century, the creation of tradition turned ruled through specialist elite manufacturers. yet this present day, an enormous array of individuals are making and sharing their very own principles, movies, and different artistic fabric on-line, in addition to undertaking real-world crafts, artwork tasks, and hands-on experiences. Gauntlett argues that we're seeing a shift from a ‘sit-back-and-be-told tradition’ to a ‘making-and-doing culture’. individuals are rejecting conventional educating and tv, and making their very own studying and leisure as an alternative. Drawing on facts from psychology, politics, philosophy, and economics, he indicates how this shift is important and crucial for the happiness and survival of contemporary societies.", "pred_label": "__label__POS", "pred_score_pos": 0.635847806930542}
{"content": "A tide has slowly been turning in the field of medicine; we are beginning to move beyond traditional small molecule drugs towards complex medicines, which are reliant on the use of advanced drug delivery systems. These medicines could, potentially, have enormous, life-changing impacts on human society and provide more focused, tailored treatments compared with historical therapies. Complex medicines – viral vectors, antibody-drug conjugates, nanomedicines, and gene therapies to name a few – are beginning to address more complex diseases. From gene editing approaches to targeted cancer treatments, these therapies offer promising treatment options for diseases with unmet clinical needs, moving beyond a one-size-fits-all approach.\nMany established medical treatments, for example, traditional chemotherapy, are non-selective. This means there is no ability to target specific cells, and healthy cells can be impacted, potentially leading to negative side effects for the patient. As a result, there is a growing demand for treatments that can better target specific cells using complex approaches, such as nanotherapeutics – engineered nanomaterials designed to deliver medical substances with high specificity to a targeted site.", "pred_label": "__label__POS", "pred_score_pos": 0.96583092212677}
{"content": "I recently had lunch with my two Vice Presidents and asked them an important question; one that I ask myself and others every year.\n\"What's my role?\", I asked. \"What do you and the team need of me?\" \"What do our clients need from me?\"\nYou might think this a case of the obvious, especially in a professional practice like ours (and yours). After all, I'm the founder, leader, sole \"official owner,\" chief technician and CEO of my firm. Isn't my job crystal clear? Aren't I simply the top dog; the big kahuna; the answer man; the keeper of the brand…the \"doctor?\"\nThe answer is clearly…No! Especially in growth-oriented firms, the role of the leader changes. In my particular case, I'm striving to build a sustainable enterprise; an asset that will serve all stakeholders well beyond Al Cleinman's time in this life. While a young 53, my current plan is to \"die in the saddle.\" Retirement, like failure, is not an option. I'll be around as long as I can contribute.\nYet there are parts of my work that are not as enjoyable as others; and parts of my current job that I don't do as well as others can. So, several years ago, I set out to fire myself from those jobs; making the strategic decision to invest in the best people I can find to help take our business to its full potential; leveraging and executing on our vision. Each year, I try to add an additional manager to assume \"the presidency\" of their specific area of influence. As a result, each year I have to assess what my role should be for the next.\nI ask you to do the same. Ask yourself that hard question, \"what is my role?\" Ask your stakeholders. But before you do, please consider whether you first must make a change in your thinking. That change, while subtle, is significant and comes under the heading of \"the words we use determines the outcome.\"\nFor many professionals, you consider your employees \"your staff.\" They work to serve you. I hear it all the time; you reference them as \"my staff,\" \"my employees\" and even \"my girls.\" If this is your thinking, I ask that you consider a change. In my opinion, the people in our employ are not there to serve us; together, we are all here to serve our customers/clients/patients/…and each other. When we think as a team, vs. a hierarchy, we realign our organizational focus. We become one with our mission. And our singular focus becomes that of creating an organization that serves our mission.\nThus, just as from time to time you must consider your team's individual roles…do we have the right person doing the right job…so too you must consider yours. We are all part of a team and roles must change as the enterprise changes.\nBy now, you may be wondering what the response was to my original question of our team leaders.", "pred_label": "__label__POS", "pred_score_pos": 0.5877106189727783}
{"content": "It is important for human users and operators to smoothly and effortlessly interact with many robots that function in the real world. Studying and developing methods for such human-robot interaction that involves complex robotic systems and multi-robot teams in a large environment becomes impractical when experiments are conducted only with real robots. A major challenge going forward is achieving maximum synergy between teams of robots and humans. The EU-funded TRAVERSE (Towards very large scale human-robot synergy) project addressed this open question by investigating and modelling human user and operator behaviour, perception and cognition through interaction with large-scale multi-robot systems. Project partners developed cooperative methods for robot team perception functionalities that are scalable to a very large number of robots. They implemented and verified a scalable multi-robot cooperative perception technique. It includes an optimisation-based estimator that runs in real time, robot-self localisation, teammate localisation and target tracking. Researchers modelled and studied human and system factors that affect the efficiency of joint duties when human operators interact with large-scale robot teams in performing a collaborative task. The joint task involved a mission to search for survivors during a disaster scenario. Extensive experiments with 35 human subjects led to two key findings. The collaborative task was performed much better where the robots were fully autonomous in exploring surroundings while human operators were only tasked with searching for survivors in the explored areas. When operators were additionally asked to control the robots, they performed significantly poorer if they did not possess good video gaming experience or training. A second finding showed only a slight benefit in increasing the number of robots in the team that performs the collaborative task. This is under the assumption that a single human operator is responsible for the actual survivor search and classification task. Increasing the number of robots, in a scenario where the robots together maintain certain formations, becomes detrimental to exploration as it rapidly increases the computational overhead. It was also found that for a small number of robots there is no significant difference in the collaborative task efficiency between an individually controlled multirobot team (where each robot is individually commanded) or a formation controlled team (where the group is commanded as a whole). TRAVERSE’s integrated multi-robot functionalities should maximise the collective performance of robot teams, while maintaining an intuitive, effortless and natural interaction with both human users and operators.\nKeywords\nHuman-robot interaction, multi-robot teams, TRAVERSE, human-robot synergy, survivor search", "pred_label": "__label__POS", "pred_score_pos": 0.7374640703201294}
{"content": "Addressing Shippers' Top Concerns\nDue to the current uncertainty of the global economy, shippers are experiencing new, unique challenges. As they navigate these challenges, understanding the shifts in consumer behavior and how they impact their supply chain is critical.\nWhile consumer mentality is improving, concerns about COVID-19's impact on the supply chain are still top of mind for shippers. New concerns and challenges are fueling shippers to shift their strategies and plans for the remainder of 2020 and beyond.\nShippers of all sizes share one common concern: keeping their people safe, whether operating in their facilities or at home. However, in many cases, this is where the similarities end.\nShippers' priorities also center on four additional areas:\n1. Maintaining operational efficiency.\n2. Keeping team members productive despite disruption.\n3. Making necessary strategic shifts in production.\n4. Managing rapid, frequent shifts in demand.\nWhile some shippers work to streamline operations, others focus on keeping up with demand. A high priority exists for supporting employees on the front lines, ensuring facilities have procured and made available crucial safety items.\nOther priorities include managing increased production, despite lower processing rates stemming from facility regulations that require social distancing and safety procedures in addition to fewer employees on each shift. Keeping supply chains running smoothly is made more difficult as shippers deal with imbalanced inventory and volatile transportation schedules.\nHow 2020 Plans Will Change\nCompanies across all areas of the supply chain have seen the importance of developing new strategies to better address the current situation and prepare for future disruptions. They will rely less on short-term, cost-based decisions and instead will prioritize being proactive, efficient, and flexible.\nWe have already seen shippers pivot their 2020 plans to address these new priorities, which include:\nWorking with a 3PL provider that offers capacity to ship freight. Collaborating directly with other shippers to share insights and best practices. Shifting live-load pickups and deliveries into drop trailer. Creating pop-up fleets at surging origin points. Narrowing the number of SKUs to reduce unnecessary variety. Focusing production toward speed, efficiency, and flexibility.\nFor some, identifying ways to better prepare their businesses for future disruption and implementing new processes will go smoothly. However, this does not mean all uncertainty can be avoided. Shippers are asking the same big questions: How do I keep employees healthy and safe? How do I limit disruption to my supply chain? How do I keep facilities up and running efficiently?\nSince the pandemic began, shippers are doing what they can to limit disruption within their supply chains and keep critical supplies and products moving.\nAs the economy moves toward recovery, we anticipate a surge in demand and, therefore, an increase in volume. Industries, especially those whose shippers slowed down or stopped, will have lean inventories and, when the demand for such products rises, need to increase production. Although shippers should be prepared to see varying results compared to their original 2020 goal, a recovery in consumer demand is not too far away.", "pred_label": "__label__POS", "pred_score_pos": 0.7773146629333496}
{"content": "Abstract\nThe original reports of human infection with Francisella tularensis noted vesicular skin rash as a manifestation. We present 2 cases of tularemia initially diagnosed as herpes simplex or varicella zoster infection. Clinicians must recognize the cutaneous manifestations of tularemia and be able to distinguish these from lesions seen with herpes viruses.\nASJC Scopus subject areas Microbiology (medical) Infectious Diseases", "pred_label": "__label__POS", "pred_score_pos": 0.9908984303474426}
{"content": "Which One Came First: Movement Behavior or Frailty? A Cross-Lagged Panel Model in the Toledo Study for Healthy Aging July 2020\nThere has been limited longitudinal assessment of the relationship between moderate-to-vigorous physical activity (MVPA) and sedentary behaviour (SB) with frailty, and no studies have explored the possibility of reverse causality. This study aimed to determine the…", "pred_label": "__label__POS", "pred_score_pos": 0.9866870641708374}
{"content": "Most concussions seem to last just a few days or weeks before symptoms are absent. However, recent research has suggested symptoms may disappear before the brain is fully healed. While symptoms may be gone, the brain may still be vulnerable and healing. The latest research to support this idea is being presented at the Sports…Read", "pred_label": "__label__POS", "pred_score_pos": 0.6564101576805115}
{"content": "I’m a board certified family medicine physician. I’ve had to learn to manage my own stress and find ways to remain calm. Through this process, I’ve discovered that one of my purposes in life is to help individuals to be made aware that not being able to get a hold on chronic stress is literally killing them. Empowering people to advance their physical and emotional well-being has been lifelong focus.\nI want to share tools, educational resources and inspiration to help people to discover their inner calm and live a more full-filled life. I look forward to sharing this journey with you.", "pred_label": "__label__POS", "pred_score_pos": 0.6904451847076416}
{"content": "ECO PRO includes an intelligent package of technologies that enables drivers to reduce fuel consumption by up to 25%. This involves reducing energy-consuming loads such as the air conditioning system or seat heating for the passengers almost imperceptibly.\nIn ECO PRO mode, the parameters of accelerator pedal and automatic transmission change. This encourages a sedate driving style with greater fuel economy. When required, however, drivers can still access the full performance by pressing down the accelerator pedal to its full extent.\nThe Bonus range displayed delivers information on how many additional kilometres have come through the efficiency-optimised driving in ECO PRO mode. The combined consumption display compares the average consumption with the current value.", "pred_label": "__label__POS", "pred_score_pos": 0.6232813596725464}
{"content": "Photo by: Orrling and Tomer S via Wikimedia Commons\nNew research suggests that a protein commonly expressed in the skin—periostin—can directly activate neurons associated with the sensation of itch. These findings may open new avenues for research into itch management.\nPublished in\nCell Reports (Apr. 7, 2020; 31:107472), the paper identified how periostin, which is abundantly expressed in the skin of individuals with atopic dermatitis and correlates with both severity and chronicity of the condition, interacts with the receptor protein αvβ3, which is expressed on sensory neurons in skin, to turn on the itch response.In a chemically-induced mouse model of atopic dermatitis, the research team found that exposure to common allergens such as dust mites increased periostin production in skin, exacerbating the itch response. However, when the researchers “turned off” the receptor protein, itch was significantly reduced.\nAs well, they exposed other animal models to recombinant mouse periostin, and observed itch-scratching behaviour within 15 minutes of exposure.\n“Periostin and its receptor connect the skin directly to the central nervous system,” said the study’s lead author, Santosh Mishra, PhD, in a press release. “We have identified the first junction in the itch pathway associated with eczema. If we can break that connection, we can relieve the itch.”\nDr. Mishra is an assistant professor of neuroscience at North Carolina State University in Raleigh, N.C.", "pred_label": "__label__POS", "pred_score_pos": 0.9449460506439209}
{"content": "SEATTLE (Scrap Monster): Unilever announced launch of 100% recyclable plastic packaging for the first time in East Africa. The announcement was made in Nairobi, Kenya. The initiative will help in reduction of thousands of tones of virgin plastics in Africa.\nThe company’s ‘Sunlight” cleaning product will come in fully recyclable packaging. The packaging used for half-a-kilogram and one kilogram of the product will be made from 100% recycled flexible materials. Henceforth, the “Sunlight” products will be marketed in new packaging in Kenya and other East-African regions.\nThe initiative is part of the “U-turn waste management project” launched in 2008, in partnership with Green Africa Trading. It aims to create a sustainable, inclusive, traceable and fair circular economy for plastics in emerging markets such as Kenya. As part of the initiative, Unilever targets reduction in use of plastic packaging by more than 100,000 tonnes by 2025. Also, it aims to use at least one-fourth of its packaging to be made of recycled plastic.\nAs per government estimates, the City of Nairobi generates nearly 2,500 tonnes of waste per day. Of this only 60% is collected, whereas only 10% gets recycled. It must be noted that Unilever’s “Zero Waste to Landfill” project had resulted in significant waste disposal in the city.\nYOU MAY ALSO BE INTERESTED IN:", "pred_label": "__label__POS", "pred_score_pos": 0.5711573362350464}
{"content": "A passenger railroad service announced that a data breach might have affected some passengers’ personally identifiable information (PII).\nIn a “Notice of Data Breach” letter sent to the Attorney General’s Office of Vermont, Amtrak revealed that it had discovered the data breach on April 16 2020.\nAmtrak looked into the matter and discovered that an unknown third party had gained unauthorized access to some Amtrak Guest Reward accounts. Those types of accounts allow passengers to build up points by riding with Amtrak so that they can ultimately claim rewards.\nWhoever was behind the data breach had abused compromised usernames and passwords to authenticate themselves on those Guest Reward accounts, Amtrak explained in its notice. In the process, those individuals might have viewed affected members’ personal information. That data did not include passengers’ Social Security Numbers (SSNs), payment card details or financial information, however.\nAccording to its statement, the passenger railroad service implemented several measures to respond to the breach and to prevent similar incidents from occurring in the future. As it explained in the letter:\nAfter detecting suspicious activity, our security team immediately investigated the issue and terminated the unauthorized access within a few hours. We also reset the passwords for potentially affected accounts. Amtrak engaged outside cybersecurity experts to confirm that the incident was contained and implemented additional safeguards to protect customers.\nThose affected by the data breach disclosed by Amtrak should consider availing themselves of the complimentary one-year Experian IdentityWorks membership offered by the passenger railroad service. They should also consider taking additional steps to safeguard themselves against attacks that could attempt to exploit their exposed information. Those measures should begin with creating a strong, unique password for their Guest Reward accounts. For best practices on how to do so, click here.\nFinally, they can use these steps to deter the efforts of identity thieves.", "pred_label": "__label__POS", "pred_score_pos": 0.6810669898986816}
{"content": "Yes! It can definitely!\nSome pet owners don’t realize the importance of basic training. When you teach your dog to sit, stand or behave properly, you are actually teaching him how to stay safe and healthy for years to come. You want your pet to be a good, social being who obeys you always. Consistent training can help you achieve this goal. Today, out vets in Burlington will discuss how effective and consistent training can be a bliss for your adorable pet.\nSit/stay This basic command will prevent your pet from running out of your house and getting hurt by cars or other animals. It allows you to have complete control over your pet especially when you are brushing, bathing or teaching them something new. This also promotes calm behavior and helps eliminate major behavior issues in your pets. Recall (cats too) This can help you establish a strong bond with your pet. It can save your pet from any potential threat or harmful situation. Your pet will rely on you for the next move and you can guide him according to the situation. Drop it It allows you to retrieve things without punishing your pet. It develops a sense of trust between you and them. This can protect your pet from ingesting any harmful items such as foreign objects, toxins, even people food that can cause severe illnesses. Walk on loose leash This makes walking more fun as you both can enjoy it. Moreover, it also promotes good physical fitness. There won’t be any harsh pulling so the chances of getting hurt or injuries to the trachea (windpipe) or spine are minimal. This doesn’t mean that you use a retractable leash. You want your pet to learn to walk gently without leash.\nThis basic training can go a long way in promoting good health. By establishing strong bond with your pet, you prevent various behavioral issues. It makes pet ownership a strong and pleasant experience for everyone.\nIn case, you are experiencing behavioral issues in your pets, contact Bay View Park Animal Hospital in Burlington. Our vets in Burlington will help determine and prevent the root cause of the problem.", "pred_label": "__label__POS", "pred_score_pos": 0.7349792718887329}
{"content": "Is your health center experiencing high turnover? Are you trying to make the case for stronger workforce retention efforts within your organization? Are you struggling to figure out what is contributing to turnover at your organization? If you answered yes to one or all of these questions, then you will want to join ACU’s webinar series focusing on health center workforce turnover.\nThis series will explore trends in healthcare workforce turnover, the financial cost of turnover on health centers, its effect on staff members and patients, and strategies that can be taken to minimize turnover. As part of this series, you will receive two tools to support your workforce retention efforts. The first is a financial impact calculator that shows the financial cost of turnover at your organization. The second is a tool to assess organizational characteristics that may be contributing to turnover. By the end of the series, you’ll be ready to take steps to tackle turnover at your organization.\nThis series will be of interest to health center leaders and human resource managers. Each session builds on the previous. To gain the most from this series, participants are encouraged to attend all three sessions.\nLearning Objectives\nBy attending this series, you will:\nUnderstand the impact that provider turnover has on health centers, staff, and patients Learn how to identify organizational risk factors contributing to turnover Identify steps to reduce turnover\nRegister once to attend the entire series:", "pred_label": "__label__POS", "pred_score_pos": 0.8485846519470215}
{"content": "What is an En • the • o • gen?\nAn entheogen is a natural plant or fungi substance that initiates non-ordinary states of consciousness which can inspire cognitive, emotional, relational, and spiritual growth and healing. Entheogens are naturally occurring and have been consumed for millennia by humans. In many cultures they are sacred and some entheogens are already recognized as such by existing U.S. law. Leading medical researchers have clinically demonstrated that entheogens have significant healing outcomes for individuals suffering from conditions including addiction, depression, trauma and terminal illness.\nEntheogens include: psilocybin containing “magic” mushrooms, mescaline containing cacti, iboga containing plants, and/or DMT-containing plants and preparations, such as ayahuasca.\nResearch\nLeading medical researchers at Johns Hopkins, New York University, UCLA, the Imperial College in London, and elsewhere have clinically demonstrated that entheogens have significant healing outcomes for individuals suffering from conditions including addiction, depression, trauma and terminal illness. Below is a brief summary of existing research:\nWhat are some of the mental health benefits of entheogenic use? A variety of studies have found that psilocybin and ayahuasca can produce dramatic and lasting reductions in the symptoms of treatment-resistant depression. Psilocybin can reduce symptoms of obsessive-compulsive disorder (OCD). Psychedelic-assisted psychotherapy can reduce depressed mood, anxiety, and death anxiety; and increase quality of life, life meaning, and optimism in cancer patients. Psilocybin can be a useful tool for lowering psychological defenses and treating PTSD. Lifetime use of psychedelics has been associated with significantly reduced odds of psychological distress and suicidal planning and suicide attempts. There is recent evidence that psilocybin can be highly effective for smoking cessation and more clinical trials are currently underway. A large body of literature dating back to the 1950s has found that psychedelics are effective at treating alcoholism and reducing alcohol misuse. Ibogaine is emerging as one of the most effective treatments for opioid use disorder, reducing or eliminating withdrawal symptoms and preventing relapse. What are some of the societal benefits of entheogenic use? Administration of psilocybin has led to perceptions of an increased connection to nature and lifetime psychedelic use predicts pro-environmental behavior such as saving water and recycling. Psychedelic use is associated with reduced rates of criminality across a wide range of measures, including a reduced likelihood of: supervision failure and recidivism, larceny/theft, assault, arrest for property crimes, arrest for violent crimes, and intimate partner violence. What are some of the ways entheogenic use promotes personal and spiritual growth ? Entheogens can induce mystical and spiritual experiences, including a sense of unity, transcendence of time and space, and positive mood. Users often rate their trip as “one of the five most personally significant experiences in their life.” Psilocybin use can lead to positive changes in personality; such as increases in empathy, openness, conscientiousness, and extraversion and decreases in neuroticism. Psychedelic use can facilitate creativity and problem-solving. Ritualistic and long-term use of ayahuasca has led to higher ratings of well-being, life-purpose, and prosocial behavior, as well as perceptions of a more healthy lifestyle and reduced prescription drug use. High-dose psilocybin sessions in combination with meditation can lead to increases in prosocial attitudes and behaviors and healthy psychological functioning, including in measures of interpersonal closeness, gratitude, life meaning/purpose, forgiveness, death transcendence, daily spiritual experiences, and religious faith and coping.", "pred_label": "__label__POS", "pred_score_pos": 0.5465285778045654}
{"content": "Can Changing Demographics or Refinancing Behaviors Explain the Rising Levels of Housing Debt Among Older Americans?\nThe share of older households with debt secured by their primary residence more than doubled between 1995 and 2016. This study uses the Survey of Consumer Finances (SCF) to examine the sources of this shift. The empirical analyses first use a series of regressions to examine the relative influence of several hypothesized demographic contributors. The results suggest that these factors explain approximately one quarter of the increase in housing debt. The remainder is shown to be attributable to factors that affect the incidence of housing debt conditional on homeownership and the number of years that households have owned their homes, such as equity extraction, refinancing, and extended financing terms. The detailed loan information in the SCF further suggests that rate refinancing and associated term extensions may be an overlooked contributor to the rise in housing debt.", "pred_label": "__label__POS", "pred_score_pos": 0.556386411190033}
{"content": "Abstract\nCertain dermatoses that present during pregnancy have a predilection for populations with skin of color (SOC). Additionally, certain systemic diseases such as systemic lupus erythematosus tend to be more aggressive during pregnancy and confer worse prognoses in women with SOC. The purpose of this review is to highlight the unique implications of selected diseases during pregnancy as it relates to SOC. Dermatologists should be vigilant for the unique clinical variations of dermatological conditions in patients of color who are pregnant to ensure correct diagnoses and optimize treatment outcomes.\nKeywords dermatoses pregnancy skin of color ASJC Scopus subject areas Dermatology", "pred_label": "__label__POS", "pred_score_pos": 0.7561147809028625}
{"content": "How the Government can support your R&D\nSCROLL\nR&D funding support\nThe RDTI is part of a wide range of government initiatives designed to support R&D activity at different stages of business growth.\nOther available R&D funding options include Inland Revenue's R&D loss tax credit\nIt's important to note that the RDTI can be claimed alongside the R&D loss tax credit. It can also be claimed alongside the other R&D funding options listed below, but not for the same expenditure or for required co-funding.\nExplore the downloadable infographic and other information on this page for an overview of some of the R&D funding options available to help you achieve your innovation goals.\nR&D Tax Incentive R&D Loan Scheme Getting Started Grants Project Grant R&D loss tax credit Student Grants How can I access funded expertise to help with a challenging research project? I want to add a highly skilled graduate to my R&D team, is there funding to assist? Government Support for R&D Commercialisation and Business Innovation\nAdditional government support is available to help commercialise R&D outputs and to promote innovation within certain sectors of the economy. For example, NZTE offers a capability vouchers scheme to offset the costs of approved training (up to $5,000) and a low-fee business mentor service. Additionally, investment funds such as the Seed Co-investment Fund and the New Zealand Venture Fund (NZVIF) can provide extra capital to startup and early stage businesses.\nIt’s worth being aware that while many of these R&D commercialisation and innovation support options can be claimed alongside the RDTI, some may restrict you from claiming certain expenditure, or even altogether.", "pred_label": "__label__POS", "pred_score_pos": 0.9235777258872986}
{"content": "Indications: Formulated to assist with relieving constipation and help promote healthy bowel function.\nMay support\n- Regular bowel movements\n- Promotion of healthy gut flora\n- Cleansing large bowel\n- Tonifying the nervous system\nIngredients: *Haritaki (Terminalia chebula), *Amalaki (Embelica officinalis), *Fennel (Foeniculum vulgare), *Senna Leaf (Senna alexandrina), *Trivruth (Operculina turpenthum), *Licorice (Glycyrrhiza glabra), *Bhibitaki (Terminalia belerica), *Shalaparni (Desmodium gangeticum), *Prishnaparni (Uraria picta), *Kantakari (Solanum xanthocarpum), *Brihati (Solanum indicum), *Gokshura (Tribulus terrestris), *Bilva (Aegle mermelos), *Agnimantha (Premna integrifolia), *Shyonaka (Oroxylum indicum), *Patala (Stereospemum suaveolens), *Gambhari (Gmelina arborea). *Certified organic\nThese statements have not been evaluated by the TGA or FDA. If pregnant or breastfeeding please consult with your healthcare provider before adding these herbs to your diet.", "pred_label": "__label__POS", "pred_score_pos": 0.9989051818847656}
{"content": "Coronavirus cases continue to rise globally, with record numbers in the Southern US Sun-Belt States. The spike upwards can be attributed to a massive expansion in testing, although the hospitalisation numbers reflect a more concerning trend, triggering remedial actions in hotspots. This has dampened enthusiasm for the rambunctious ‘V-Shaped’ recovery in global equity markets. This has also reversed trends in the US Dollar, as risk appetite diminishes, the Dollar becomes more attractive. The EUR fell back to 1.1200, while the GBP now tests 1.2400, on the downside.\nUS markets were boosted by actions taken by the FDIC, to remove restrictions on banks, imposed following the GFC. The rally in Bank shares offset fears over the rising spread of the coronavirus. Trade concerns remain, as the EU rejects US threats over European aircraft subsidies, while China continues to be at risk of further US sanctions. The trade threat is the biggest danger to the trade exposed commodity currencies and the rise in the reserve, reduced enthusiasm for the trans-Tasman currencies. The AUD slipped back to 0.6850, while the NZD tests 0.6400, despite a narrowing trade deficit. NZ Export returns improved, but imports declined, along with domestic demand. The improving headline number is economically undermined by the sharp fall in demand for imports, confirming weakness in consumer demand.\nTrade remains a big threat to markets, while the immediate threat of a virus spike, drives daily investment emotion.", "pred_label": "__label__POS", "pred_score_pos": 0.7866811156272888}
{"content": "Top’s Tire Repair is a leading tire service in the greater metro area. We specialize in all types of tire service including alignment and rim repair.\nFlat Tires can trigger the rim of the tire to rest on the tire tread or on the ground potentially creating a loss of control of the auto or irreparable damages to the tire.\nFrequently the cause of flat tires involves the penetrating of the tire by a sharp item, such as a nail, permitting air escape. Depending on the size of the leak, the tire may deflate slowly or rapidly.\nWhat happens when this occurs?\nValve stem damage resulting in air escaping from the valve or causing damages by means of intentional puncturing.\nToo much wear of the tire tread causing explosive tire failure or permitting road debris to tear through it.\nWith slow leaks due to a puncture, our technicians can often repair the tire and re-inflated it with minimum loss of time. While tires with excessive wear from worn tread, must be replaced.\nCracking or bulging treads or sidewalls may imply there is wear or weak points in the tire. Foreign items that pass through into the tire (nails, screws, glass) will most often result in a flat. If the damage to the tire in minimal it maybe repaired. If there is extensive damage we will recommend the tire be replaced. If there is tread pulling away from the body of the tire, this can cause tire failure. It has to be replaced.\nIf you find any of these conditions exist, we’ll inspect and readjust your air pressure and do a visual tire check, and where needed we may recommend you replace the defective tire.\nWe keep your tires on … Top with Top’s Tire experts! Come by your Top Tires store today.", "pred_label": "__label__POS", "pred_score_pos": 0.8713218569755554}
{"content": "Resources Solution paper – SmartChain™ Energy Management\nAccording to GTM Research, the growth in electric vehicle sales worldwide is expected to boost demand for charging points, with up to 40 million installed by 2030. McKinsey Research believes that unmanaged, substation peak-load increases from EV-charging power demand will eventually push local transformers beyond their capacity, requiring expensive infrastructure upgrades.\nThe Driivz SmartChain™ Energy Manager plays a critical role in reliably charging EVs using intelligence that ensures the safe delivery of power to electric vehicles without compromising on delivering electricity to offices and homes.\nIn our SmartChain™ Energy Management Solution paper, you will discover: Why do you need smart EV charging? How Driivz can help you overcome local grid capacity Balancing response and demand How the Driivz SmartChain Energy Manager works Additional features to help manage your energy The future: EVs for energy storage", "pred_label": "__label__POS", "pred_score_pos": 0.8221448063850403}
{"content": "Chartreux cat is a sturdy, short-haired cat with French origin, much desired for its incredible mousing skills, exotic look, and dense, water-repellent coat. This feline has a stout, muscular body, but often deemed a “potato on toothpicks,” due to its relatively short, fine-boned legs. While it is a stocky furball, the Chartreux cat is lithe and agile, graceful, and never clumsy. And, despite its Halloween-colored eyes, it has a sweet disposition and will provide its owner with years of close companionship and affection.\nOrigin of the Chartreux Cat\nTwo different conjectures surround the origin of the breed. First, it is deemed that these cats trace their roots from feral felines from Syria brought to France by crusaders in the 13th century.\nThe other and more popular theory suggests that Chartreux cats hail are felines brought by the Carthusian monks to the country. Literary references or records confirm the Chartreux cats’ previous existence at the Grande Chartreuse Monastery, where monks used them for their companionship and their hunting ability.\nThe breed, which had always been infrequent, was put into the brink of extinction in World War II. Fortunately, the Chartreux was saved due to the diligent efforts of cat breeders. However, today, the breed is still a rare breed, arriving in the United States only in 1971.\nPhysical Characteristics of the Chartreux Cat Length: 15 to 18 inches Weight: 10 to 15 pounds (Males), 6 to 11 pounds (Females) Coat Life Expectancy: 11 to 15 years Coat Color: Blue Type of Coat: Medium Eye Color: Gold, Orange, Copper\nThe Chartreux cat is a stout, muscular cat, with a conspicuous blue-gray coat and bright orange-copper to orange-gold eyes. The double coat is water-resistant, often giving a napped wool look.\nIt is often deemed a “potato on toothpicks” as its stocky build sits atop short, fine-boned legs. Other characteristics include a deep chest, fairish-sized ears, and a round head that narrows down to the muzzle. Lastly, these felines sometimes appear to be smiling due to their distinct facial bone structure.\nDespite its odd stature, the Chartreux cat has fast reflexes and is prized for its excellent mousing skills.\nChartreux Cat Personality\nThriving alongside monks for a hundred of years, the Chartreux cats have evolved to be gentle, loyal, and sweet-tempered felines. They are people-oriented, always craving for human companionship and up for a snuggle.\nAs these cats build strong bonds with their owners, they can be seen following them around wherever they go. They would also amuse guests and visitors, as these furballs can warm with them pretty quickly. Having babies or toddlers in the house should not be an issue as Chartreux will harmoniously live with them, making them an ideal family cat.\nWhen it comes to activity levels, Chartreux cats have their energetic and playful side. Known for incredible hunting skills, they love toys that move or a good game of fetch. Otherwise, they can be seen surveying the house in search of something to chase or play with.\nChartreux cats are also blessed with smarts. They can learn their names in no time and can be trained to come to their owner’s calls. However, these furballs are known for being quiet or even silent. They may open their mouths, but won’t produce any “meow.” Instead, they make small trills or chirps, which tends to be surprising given their large body. Moreover, they “talk” to their families in other ways, such as purring mightily or staring using their Halloween-colored eyes.\nCaring for the Chartreux Cat\nChartreux cats need relatively low-maintenance when it comes to grooming. Their dense, short coat is repellent to water, and shedding requires regular combing instead of brushing to keep them healthy and prevent any knots. The undercoat sheds twice a year, but regular combing keeps it controlled and manageable. As with other cats, other parts of the grooming routine include dental hygiene, ear cleaning, and nail trimming.\nAs energetic and playful felines, they will play whenever they want to. While these furballs can easily find something to play with, if there is no toy available, it is best to provide them with playthings, as no one would like them to create one out of any valuable stuff in the house.\nThese cats prefer hunting games, in which they can showcase their hunting prowess. Not only will it stimulate their innate skills, but it would also ensure that they get adequate exercise. Chartreux cats may be naturally stocky and muscular, but they must engage in regular interactive plays to keep their weight at bay and avoid obesity.\nSince they previously lived in large monasteries, these cats will be happiest if they have a vast place to explore. They will love plenty of spaces where they can sleep, play, or roam to look out for rodents.\nIn terms of health, Chartreux cats are generally a sturdy breed. However, they are vulnerable to some genetic diseases, the same as other cat breeds, such as medial patellar luxation and polycystic kidney disease. The best way to keep these furballs healthy is through proper nutrition, ample exercise, and regular consultations with the vet to prevent or detect any condition.\nChartreux cats are perfect for families looking for easy-going, quiet, and loving companions to their homes. They are fun to have around and will reward their master’s affection with their enigmatic smiles, polite disposition, and sweet devotion. Treating them patiently and kindly and will ensure any owner a friend for life.", "pred_label": "__label__POS", "pred_score_pos": 0.7476875185966492}
{"content": "Abstract\nFor patients with impaired breath-hold capacity and/or arrhythmias, real-time cine MRI may be more clinically useful than breath-hold cine MRI. However, commercially available real-time cine MRI methods using parallel imaging typically yield relatively poor spatio-temporal resolution due to their low image acquisition speed. We sought to achieve relatively high spatial resolution (∼2.5 × 2.5 mm\n2) and temporal resolution (∼40 ms), to produce high-quality real-time cine MR images that could be applied clinically for wall motion assessment and measurement of left ventricular function. In this work, we present an eightfold accelerated real-time cardiac cine MRI pulse sequence using a combination of compressed sensing and parallel imaging (k-t SPARSE-SENSE). Compared with reference, breath-hold cine MRI, our eightfold accelerated real-time cine MRI produced significantly worse qualitative grades (1-5 scale), but its image quality and temporal fidelity scores were above 3.0 (adequate) and artifacts and noise scores were below 3.0 (moderate), suggesting that acceptable diagnostic image quality can be achieved. Additionally, both eightfold accelerated real-time cine and breath-hold cine MRI yielded comparable left ventricular function measurements, with coefficient of variation <10% for left ventricular volumes. Our proposed eightfold accelerated real-time cine MRI with k-t SPARSE-SENSE is a promising modality for rapid imaging of myocardial function. Keywords MRI cardiac cine compressed sensing heart k-t SPARSE-SENSE real-time ASJC Scopus subject areas Radiology Nuclear Medicine and imaging", "pred_label": "__label__POS", "pred_score_pos": 0.6490975618362427}
{"content": "Abstract:\nCard-based cryptography, as first proposed by den Boer [den Boer, 1989], enables secure multiparty computation using only a deck of playing cards. Many protocols as of yet come with an “honest-but-curious” disclaimer. However, modern cryptography aims to provide security also in the presence of active attackers that deviate from the protocol description. In the few places where authors argue for the active security of their protocols, this is done ad-hoc and restricted to the concrete operations needed, often using additional physical tools, such as envelopes or sliding cover boxes. This paper provides the first systematic approach to active security in card-based protocols. The main technical contribution concerns shuffling operations. A shuffle randomly permutes the cards according to a well-defined distribution but hides the chosen permutation from the players. We show how the large and natural class of uniform closed shuffles, which are shuffles that select a permutation uniformly at random from a permutation group, can be implemented using only a linear number of helping cards. This ensures that any protocol in the model of Mizuki and Shizuya [Mizuki and Shizuya, 2014] can be realized in an actively secure fashion, as long as it is secure in this abstract model and restricted to uniform closed shuffles. ... mehrUniform closed shuffles are already sufficient for securely computing any circuit [Mizuki and Sone, 2009]. In the process, we develop a more concrete model for card-based cryptographic protocols with two players, which we believe to be of independent interest.", "pred_label": "__label__POS", "pred_score_pos": 0.9762120842933655}
{"content": "Orphanet journal of rare diseases2017; 12 (1): 71 Abstract\nPatients' stories of their illnesses help bridge the divide between patients and providers, facilitating more humane medical care. Illness narratives have been classified into three types: restitution (expectation of recovery), chaos (suffering and loss), and quest (unexpected positive effect from illness). Undiagnosed patients have unique illness experiences and obtaining their narratives would provide insights into the medical and emotional impact of living with an undiagnosed illness. Adults and children with undiagnosed diseases apply to be evaluated by the Undiagnosed Diseases Network (UDN). Written illness narratives from 40 UDN applicants, including 20 adult probands who applied for themselves and 20 parents who applied for their children, were analyzed for: 1) narrative content and 2) narrative type.Narrative content: could be grouped into three themes: 1) Expectations of the UDN: the majority felt they had no further healthcare options and hoped the UDN would provide them with a diagnosis, with the adults expecting to return to their previously healthy life and the parents wanting information to manage their child's healthcare. 2) Personal medical information: the narratives reported worsening of symptoms and some offered opinions regarding the cause of their illness. The proband narratives had few objective findings, while parental narratives had detailed objective information. 3) Experiences related to living with their undiagnosed illness: frustration at being undiagnosed was expressed. The adults felt they had to provide validation of their symptoms to providers, given the lack of objective findings. The parents worried that something relevant to their child's management was being overlooked. Narrative type: All the narratives were of the chaos type, but for different reasons, with the probands describing loss and suffering and the parents expressing fear for their child's future. The parental narratives also had elements of restitution and quest, with acceptance of \"a new normal\", and an emphasis on the positive aspects of their child's illness which was absent from the probands.These narratives illustrate the chaos that coexists with being undiagnosed. The differences between the proband and parental narratives suggest that these two groups have different needs that need to be considered during their evaluation and management.\nView details for DOI 10.1186/s13023-017-0623-3\nView details for PubMedID 28416019\nView details for PubMedCentralID PMC5392939", "pred_label": "__label__POS", "pred_score_pos": 0.5190368890762329}
{"content": "On other topics, online discussions, like one at a \"hub\" for infectious diseases set up by the American College of Emergency Physicians – have had clear, potentially life-saving impacts on how patients are evaluated and treated.\nAt the Jack D. Weiler Hospital in the Bronx, N.Y., a 70-year-old woman came in with a mild fever, nausea and vomiting that was causing low blood pressure. Doctors initially thought it might be a typical seasonal illness, said Deborah White, vice chair of emergency medicine at the facility.\nThen doctors in Washington, where an outbreak in a nursing home led to the first U.S. hot zone, noted on the ACEP hub that many older COVID-19 patients exhibited mainly gastrointestinal issues like nausea and diarrhea.\nBack in the Bronx, the 70-year-old patient immediately hit doctors' radar screen as a potential coronavirus case. The hospital – which helps care for patients of nearby nursing homes, started grouping all elderly patients with gastrointestinal symptoms and low blood pressure together as potential COVID-19 patients, a process called cohorting.\n\"That became a paramount piece of information for us,\" White said, noting that previously such patients were often sent back home or returned to nursing homes with orders of bed rest and a simple diet. Now, however, some of those patients are testing positive. Cohorting, she noted, isn't traditionally done in such cases, but instant information-sharing allowed a rapid, important change.\n\"This is what we do, pivoting in the very moment,\" White said. \"It's the bread and butter of emergency medicine.\"___\nDistributed by Tribune Content Agency, LLC.", "pred_label": "__label__POS", "pred_score_pos": 0.6926769018173218}
{"content": "A doctor needs to know about any postmenopausal bleeding to exclude the possibility of uterine cancer or hyperplasia, a precancerous condition. Fortunately, cancer is the cause of postmenopausal bleeding in only about 10% of women who have this symptom.\nAn evaluation of postmenopausal bleeding begins with an exam of the vagina and cervix to see if the blood is coming from the lower genital tract. A pelvic ultrasound is often used to check the internal organs, including the uterus, Fallopian tubes and ovaries.\nThe width of the uterine lining (the endometrium) is measured during the ultrasound. It should be quite thin after menopause. That's because estrogen levels are too low to stimulate growth of this tissue. If the endometrium is thick, a biopsy is used to gather cells that will be inspected under a microscope. This can determine if cancer or a noncancerous (benign) process caused the thickening.\nIn women not yet in menopause, estrogen is secreted by the ovaries each month to prepare the uterus for pregnancy. Estrogen levels rise in the first two weeks of a menstrual cycle to stimulate the growth, or proliferation, of the endometrium. If a pregnancy does not occur, the endometrium sheds as the menstrual period.\nAfter menopause, the production of estrogen slows and eventually stops. Since this is a gradual and sometimes irregular process, proliferative endometrium may still be found in early menopausal women. Proliferative endometrium is a noncancerous (benign) and normal cause of thickening seen on an ultrasound.\nContinue Learning about Menopause\nImportant: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.", "pred_label": "__label__POS", "pred_score_pos": 0.808377206325531}
{"content": "Alternating current (ac) measurements involve more factors than direct current (dc) measurements. Let’s look at how some of these affect the measurement. We’ll focus on signals with a fundamental frequency below 1kHz. This is where digital multimeters and panel meters are typically used. Higher fundamental frequencies require instrumentation with wider bandwidth, such as audio meters or oscilloscopes.\nThe basic ac waveform is a sine wave with no dc value. In the diagram, ① indicates the peak amplitude‚ is the peak-to-peak, ƒ is the rms value (sometimes described as the heating value), and is the waveform average value. The relationships between these values in a sine wave are:\npeak-to-peak = 2 x peak rms = 0.707 x peak average = 0.636 x peak\nMany analog and digital meters are average responding but calibrated to display the equivalent rms value for a sine wave. Their accuracy is degraded when measuring distorted (i.e. non-sinusoidal) waveforms. An rms responding meter (often stated as true rms or TRMS) can tolerate some waveform distortion without derating. The amount of distortion is often indicated by a crest factor specification. Crest factor (CF) is the ratio of peak to rms value. The crest factor of a sine wave is 1.414 (the √2). CF of a full-wave rectified sine is also 1.414, but a half-wave rectified sine is 2. The CF of a square wave is 1; triangle wave √3. Low duty cycle pulse trains can have crest factors >10. Some meters will specify an accuracy derating for high crest factor signals.\nThe period is the time to complete one full cycle of the ac waveform. Frequency, expressed in Hertz, is the inverse of the period. Frequency is another factor that affects measurement accuracy. A meter has a bandwidth where the specified accuracy applies. On panel meters intended for measurement of mains circuits, this is often 45-100Hz, with some specialty meters operating down to 25Hz or up to 400Hz. A pure sine wave has only a fundamental frequency. Distortion adds high-frequency components to the signal. These may be beyond the bandwidth of the meter, which will degrade the stated accuracy. For example, a ±1V, 100Hz square wave has a 1.25V peak fundamental at 100Hz and odd harmonics of reduced amplitude at 300, 500, 700Hz, etc. Many electronic lamps and motor controls introduce significant distortion to a sine waveform and are therefore best measured with a TRMS responding meter.\nVoltage measurements are made across the load or device Voltage measurements are made across the load or device under test. Three voltmeter input configurations are frequently used.\nThe first voltmeter block shows the meter connected directly across the load. This is typical for an analog meter or digital meter on a range below 4V full scale. An important meter specification for low-frequency signals in this configuration is input resistance. High resistance is desired to avoid altering the voltage across the load. Most voltmeters include a capacitor in series with the meter to block any dc voltage. This allows the meter to display the ac signal even in the presence of a large dc offset. Some TRMS multimeters include an ac+dc function. In this mode, the blocking capacitor is switched out so the meter reads the dc offset and the ac signal together.\nThe second voltmeter block includes a voltage divider to reduce the meter input to a level compatible with the voltmeter circuit. The sum of the two resistors must be a high value to avoid loading the circuit under test. The third voltmeter scheme is popular in meters dedicated to AC mains measurements, where there is no dc offset. An internal potential transformer reduces the ac signal feeding the meter section and isolates it from the ac source. For these same reasons, some meters are specified for use with an external potential transformer.\nVoltmeter Loading Example: A typical DMM has an input resistance on the ac function of 10MΩ. If the circuit being measured has Rsource = 1kΩ and Rload = 10kΩ, connecting that DMM across Rload will change the voltage by <0.01%. However, a meter input resistance of 100kΩ would change the voltage by almost 1%. Fortunately, AC mains circuits have resistances significantly lower than this example, so connecting a voltmeter has a negligible effect.\nCurrent measurements are made by placing an ammeter in series with the load. The preferred location for the ammeter is in the low leg of the circuit. This minimizes the voltage at the meter terminals, thus reducing leakage currents to earth (which would cause a reading error). This location also reduces the safety risk to users.\nThe first ammeter circuit shows a typical analog meter. Here it is important to minimize the resistance the meter adds to the circuit. This is often expressed as a burden, which is the voltage drop across the meter at full-scale current. The second ammeter block shows the configuration of a typical digital meter. A low-value resistor is placed in series with the load and the voltage across that resistor is measured to determine the circuit current. In the third ammeter block, a current transformer reduces the current level and isolates the meter circuitry from the circuit being tested. In some cases, an external current transformer may also be used. Transformer-rated analog ammeters are specified and calibrated for use with an external current transformer.\nAmmeter Loading Example: A digital ammeter has an internal resistor of 0.1Ω for the 1A range. A 24V ac circuit drawing 1A has a combined source and load resistance of 24Ω. The addition of the meter resistance decreases the current by 4mA, causing the meter to read low by 0.4%. Using the 10A range with an internal resistor of 0.01Ω would reduce this error. However, accuracy is affected by operating at 10% of full scale.\nCareful selection and application of an ac meter, either analog or digital, allows voltage or current measurements with sufficient accuracy for industrial applications. AC power measurements involve the measurement of both voltage and current, plus the phase relationship between them. These more complex measurements are described in several application notes.", "pred_label": "__label__POS", "pred_score_pos": 0.8710514903068542}
{"content": "Solar energy conversion must arguably play a central role in sustainably providing large-scale power to a growing global population currently undergoing a massive surge in industrialization. At present, this goal remains elusive owing to the absence of means for economical solar power generation. Organic and hybrid organic / inorganic photovoltaic cells (OPV) have the potential to fill this gap, but are currently unable to meet the efficiency required for a significant impact on the energy market. The delicate balance between high interfacial area required for efficient exciton dissociation and high mobility of both types of carriers poses fundamental challenges to device architecture that require novel spectroscopic insights on microscopic length-scales. Scanning photoionization microscopy (SPIM) is capable of providing frontier orbital position at high spatial resolution, thus generating a detailed map of interfacial electronic structure at sub-micron length-scales. We will discuss recent advances to implement this form of microscopy in the context of nano- and meso-structured hybrid materials for solar energy conversion.", "pred_label": "__label__POS", "pred_score_pos": 0.7737481594085693}
{"content": "COVID-19 has emphasized the\nimportance of getting accurate information to the right individuals, especially in a time where all our systems and resources are constrained. Under these restrictions, information efficiency is paramount.\nIn lieu of this, there will be a pivot towards '\ninformation guides' and existing players/institutions have an opportunity to take on this role. It's not enough to put information out there; users need solutions that enables them to self-triage and identify the resources that apply to their situation quickly.", "pred_label": "__label__POS", "pred_score_pos": 0.8788294196128845}
{"content": "Our curatorial approach rests on sound frameworks, process and quality control, fostering creativity, invention and innovation.\nVestibulum scelerisque odio sed suscipit viverra.\nSed libero purus, venenatis in leo vel, pharetra fringilla lectus.\nA survey and / or focus groups of your learners before you start can provide valuable information.\nProject components can be identified through the option of a facilitated workshop ensuring all collaborators remain on the same page throughout the project.\nFortnightly reviews ensure changes are implemented at the most convenient time, saving costly amendments after the fact, while allowing the project to breathe, evolve and adapt.\nOur curatorial approach ensures if we don’t know a subject intimately, we don’t bluff, we bring in advisors, suppliers, creators and technicians as subject matter experts. By example, our Accessibility Consultant ensures we can meet our commitment to universal inclusion.\nUser and client feedback during and after completion will ensure diligent assessment and improvement.", "pred_label": "__label__POS", "pred_score_pos": 0.9983233213424683}
{"content": "Detection of quantitative trait loci affecting caffeine metabolism by interval mapping in a genome-wide scan of C3H/HeJ x APN F(2) mice.\nJOURNAL:\nDrug metabolism and disposition: the biological fate of chemicalsDec 1999,Vol 27, pp. 1375-80\nABSTRACT:\nCaffeine metabolite ratios have been widely used to measure cytochrome P-450 1A2 activity in humans. Serum paraxanthine/caffeine ratio is one such index of this activity. We had previously demonstrated genetic variation of this trait among inbred mouse strains. In the present study, we have undertaken a genome-wide scan for quantitative trait loci affecting this trait with an interval mapping approach on an F(2) intercross population of acetaminophen nonsusceptible and C3H/HeJ inbred mice. A statistically significant association (log-likelihood ratio = 25.0) between a locus on chromosome 9, which colocalized with the murine Cyp1a2 locus, and the plasma paraxanthine/caffeine ratio was identified. This result suggested the presence of an expression polymorphism affecting this gene. A second locus was identified on chromosome 1 (log-likelihood ratio = 9.7) for which no obvious candidate gene has been identified. The influence of this locus on the paraxanthine/caffeine index was more significant among males (log-likelihood ratio = 6.3) than females (log-likelihood ratio = 3.6). A third locus was identified on chromosome 4 with a less statistically robust association (log-likelihood ratio = 3.4) to the paraxanthine/caffeine phenotype. Collectively, these three loci accounted for 63.2% of the variation observed in the F(2) population for this phenotype. These results demonstrate the potential for genetic variation arising from factors other than CYP1A2 activity to influence the plasma paraxanthine/caffeine ratio in mice. This study demonstrates the utility of quantitative genetics in the analysis of polygenic drug metabolism.PUBMED: 10570017 Find other GeneSets from this publication", "pred_label": "__label__POS", "pred_score_pos": 0.9205015897750854}
{"content": "The Indian government closed international and domestic air travel to contain the spread of novel coronavirus, or COVID-19. While suspension of all international services was announced first, after just few days, a total suspension of air traffic was announced, thereby, vacating the skies of India of any commercial flights.\nSuspending all domestic air travel was an act well timed – 48 hours after the last scheduled international flight, which meant that passengers having connecting flights had reached their destinations. With less than 48 hours to plan, execute and shut down, it was a scramble for airlines to get planes to base along with the crew.\nWith the uncertainty regarding the duration of the aviation closure, it was imperative that the airlines send the crew back to their home base. Accordingly,\nas soon as the government announced the deadline of 11:59pm on March 24, 2020, for the last of flights to land, a new scramble erupted. A battle to store the aircraft. An endeavour to park them where they can be secured and safe.\nDelhi airport – India’s largest by traffic and area — had already closed one of its three runways for parking of planes. This was not an unseen phenomenon. Zurich, Frankfurt, Atlanta – a lot of global peers — among others, had done the same. But India has a different problem. The nation is still partially regulated and airlines do require permission from airport operator or the government for night parking an aircraft. An aircraft cannot be imported without having night parking in place. As a result, the over 650 aircraft have a designated night parking slot when they were imported and allowed to operate in India. Thus, ideally, every aircraft should have a dedicated parking space, at least on paper. However, with majority of the airlines in the country being Low Cost Carriers, airlines obtain night parking permission from one airport and rotate the aircraft the whole night without really parking there, which is a common practice with LCCs as their business model is built around ensuring that every aircraft is fully utilised. With a lockdown in place, it was imperative that the crew had to return to base and hence additional pressure was put on major cities, further disturbing the parking pattern of over 650 aircraft.\nSo, how is India tackling the aircraft parking issue?\nDelhi has one-third of India’s commercial fleet parked after the grounding. A staggering 205 aircraft across airlines are parked at the New Delhi airport. Mumbai is home to nearly 100 aircraft across airlines being parked, followed by Bengaluru, which has 71 aircraft, and Hyderabad with 61. Kolkata is housing 54 aircraft, while Chennai being an abode to 53. And here lies the logistic nightmare: IndiGo has parked its aircraft at eighteen airports across the country, while SpiceJet and GoAir have parked at eleven airports each. Air India has parked its aircraft at seven airports in the country, while Vistara and AirAsia India have parked their aircraft at six and five airports, respectively.\nA parked plane does require some maintenance and airlines would be using minimal manpower for the same, at times, at places where facilities for carrying out the maintenance might not be always guaranteed, since aircraft are now distributed throughout the country. And thus, when the restrictions will be lifted, they would be in phases and when it happens, it would imply another logistical nightmare for the airlines for route management and crew transportation.\nWhat do you think about the after effects of this shutdown? How long will it take for airlines to return to business as usual? And most importantly, do you think it would be ‘usual’ in the first place?\nThis content was provided to MentourPilot by provider, Travel Radar Media. Travel Radar offers high quality content in partnership with Mentour", "pred_label": "__label__POS", "pred_score_pos": 0.5797896981239319}
{"content": "Abstract\nHelping professionals are easy exposed to secondary traumatic stress (STS) when engaging in treatment process with clients who had been traumatized primarily. STS contributes to different degrees of psychological distress such as compassion fatigue and burnout as well as negative impacts on job satisfaction and subjective sense of role competence.\nObjectives:The study was to identify protective factors for helping professionals’ from psychological distress that might help increasing role competence and quality of human services. Methods:A cross sectional quantitative approach was conducted through online convenient sampling from 71 helping professionals (mean age=37.7; 87.3% female), measured the areas of mindfulness traits, quality of supervision, secondary traumatic stress and sense of role competence. Results:Mindfulness traits was positively associated with role of competence and was negatively associated with secondary traumatic stress. Quality of supervision had no significant correlation with role of competence. Regression analysis proved that STS partially mediated the relation between mindfulness and role competence. Two subscales of mindfulness traits, attention and present focus, had significant influence on role competence. Conclusion:Mindfulness traits were found to be a potential predictor and protective factor for helping professionals from psychological distress. Activities with mindfulness elements are suggested for stress reduction. Meanwhile, further researches on protective factors for helping professionals are recommended. All rights reserved.\nOriginal language English Publication status Published - 2018 Keywords Secondary traumatic stress Role competence Mindfulness Alt. title: Secondary traumatic stress, role competence Theses and Dissertations Thesis (M.Soc.Sc(Psy))--The Education University of Hong Kong, 2018.", "pred_label": "__label__POS", "pred_score_pos": 0.6996533870697021}
{"content": "With demand for businesses to be ‘greener’ and for more efficient growth, environmental management is now a key focus for all organizations. BSI's report on sustainability discusses pressing topics for organizations, including:\nEnvironmental challenges in business Engaging with the UN Sustainability Development Goals The circular economy Smart cities Global water stewardship Sustainable energy management\nUse the form below to download the report:", "pred_label": "__label__POS", "pred_score_pos": 0.658328652381897}
{"content": "The water industry introduced an alternative dispute resolution service called WATRS (the Water redress Scheme) in April 2015.\nIf customers are unhappy with the outcome of their case following the company’s formal complaints procedure and CCWater’s mediation, they can approach WATRS for an independent and binding decision on the matter. Take up of the scheme has been lower than expected, and this research is aimed to understand why that is.\nThe key findings include: Despite CCWater signposting eligible customers to the scheme, only three in ten were aware of the scheme; Communication about WATRS could be made stronger by making it bigger, making it stand out more or having a separate email or letter about it; and The most cited reason for not approaching WATRS was that the customer had given up or saw no point in continuing.\nWe intend to address these findings by strengthening our signposting to WATRS and making a link to WATRS case studies more visible on our website. This enables customers to see positive outcomes of what WATRS has achieved. We will also include a leaflet about WATRS in our closure letters, which will be provided to CCWater by the panel that has oversight of the WATRS scheme.", "pred_label": "__label__POS", "pred_score_pos": 0.8125284910202026}
{"content": "If Katie Price or David Beckham managed a hedge fund, they would probably underperform their rivals, recent research suggests.\nThat, at least, is one conclusion you could draw from a paper published earlier this month by academics at Edhec Business School and Boston College. It found that a hedge fund with media coverage will, on average, underperform a rival with no coverage by 3.5 percentage points. The difference is more pronounced among smaller funds, and among the largest funds the difference is \"not significant\".\nThe study doesn't establish a causal link. The authors suggest that media coverage could lead to increased flows, which would affect performance, or that journalists tend to focus on negatively performing funds - but they dismiss both hypotheses based on the data.\nStill, the research focuses only on North American funds, so Katie and Becks might face better odds than their peers across the pond.\nSee the research here:\nhttp://papers.ssrn.com/sol3/papers.cfm?abstract_id=1563703", "pred_label": "__label__POS", "pred_score_pos": 0.8123546838760376}
{"content": "This event has passed. Implementing Blockchain Within Governments January 7, 2019 @ 4:00 pm - 6:00 pm\nKausar Samli, VP of Global Delivery for Learning Machine, will address the key topics and values relevant for governments considering blockchain implementations.\nTalk Summary\nIn this age of global economic transformation, as nation-states transition from a local industrial economy to a global digital economy, technology-driven social evolution increasingly requires an information economy model of credentialing. The reforming of paper records into blockchain-secured digital documents offers a faster, simpler, and more secure way to record transactions, validate authenticity, and verify identity. These attributes directly prevent fraud, enhance operational efficiency, enable new revenue streams, increase brand and market value, and simultaneously empowering participants to be owners of official records that are theirs for a lifetime.\nNowhere is this transition more apparent than among nation-states where the constraints of a small population with limited resources necessitate innovative approaches to train, recruit, and retain a competitive workforce. Island nations like the Bahamas and Malta (and others) are at the forefront of this transformation by leveraging technologies that offer competitive advantages and attract human capital from larger nation-states. For example, both nations are implementing strategies, incentives, and legislations to facilitate a transformation into blockchain-powered governments and economies, thereby generating significant global and regional economic value. As the world leader in blockchain-secured digital records, Learning Machine has developed the technology and scalable enterprise platform to provide an information economy model of credentialing to meet market needs.", "pred_label": "__label__POS", "pred_score_pos": 0.9008538722991943}
{"content": "Good indoor air quality in Clearwater can improve health issues like allergies and asthma. Even individuals in good health without respiratory issues can benefit from clean air. Dust, smoke and other pollutants waft around in the air, causing your curtains and furniture to gather dust. By eliminating airborne dust particles, you decrease the level of exposure your respiratory system has to them.", "pred_label": "__label__POS", "pred_score_pos": 0.9168993234634399}
{"content": "What is an Offshore Closing?\nBy:\nAndrew Holland\nOccasionally we handle transactions where either a buyer or seller require a closing to occur outside of the area where the boat is currently lying. This is what we call an “offshore closing”.\nWhy would one require an offshore closing?\nThe main reason that either party would request an offshore closing most often directly coincides with potential taxation or duty ramifications on the sale of the boat in it’s given location. To avoid these potential costs, the buyer and seller may agree to perform a legal offshore closing on the sale of the boat.\nAn offshore closing can be defined as when a boat is sailed into international waters on the agreed day of closing – the required distance offshore for closing will depend on the boats location – and finalization of the closing documents is done directly on the boat once you are in international waters. Photos are taken of the GPS coordinates and signing of the required documents, along with a photos of the signer with a copy of the days newspaper to provide photographic evidence of the time and location of the finalization of the closing documents.\nOffshore closings are most often seen in states like Florida, California and in various countries in Europe.\nWhile an offshore closing does require logistical consideration that can potentially complicate the closing process, it does present potentially advantageous legal methods to avoid tax and duty on the purchase or sale of a vessel depending on the details of the transaction.\nThe procedure and requirements for an offshore closing will depend on the boats current location and where she intends to re-enter the country after the closing, so if you intend to proceed with an offshore closing it is important to consult with professionals to discuss the legal requirements that must be followed.\nFor questions, feel free to contact the Multihull Company offices at 215-508-2704.", "pred_label": "__label__POS", "pred_score_pos": 0.5855679512023926}
{"content": "Olon is a world-class drug substance contract development and manufacturing organization with expertise in API production using synthetic and biological processes for the generic market. As our exclusive sponsor of Italy, Olon has a global presence with 11 manufacturing facilities. The company’s facilities, located in Italy, Spain, the United States, India, and China, are all compliant with international requirements.\nWith several decades of experience and a strong background in chemical and biological processes, Olon is a reliable outsourcing partner that offers integrated services to support the full development of APIs.\nHow is Olon contributing to the future of healthcare?\nAs an API supplier to pharmaceutical companies worldwide, innovation is a key driver at Olon. The company invests in new technologies, capabilities, and processes to provide valuable solutions. Olon is closely eyeing the increasing need for personalized medicine and aims to further invest in high-containment capabilities and adopt continuous rather than batch processing for API manufacturing.\nThe recent COVID-19 pandemic has highlighted a critical need for a robust supply chain, as some supplier countries were placed on lockdown. Olon, with its global presence, supports health efforts through the development of multiple experimental antiviral drugs to combat COVID-19. The company will continue to develop new ideas and sustainable solutions to support the life science industry and improve the health of patients across the world.", "pred_label": "__label__POS", "pred_score_pos": 0.9083326458930969}
{"content": "Border safety is a critical part of national and international security. The U.S. Department of Homeland Security searches vehicles entering the country at land borders for drugs and other contraband. Customs and Border Protection (CBP) agents believe that such vehicles operate in groups and if the criminal links of one vehicle are known then their border crossing patterns can be used to identify other partner vehicles. We perform this association analysis by using mutual information (MI) to identify vehicles that may be involved in criminal activity. CBP agents also suggest that criminal vehicles may cross at certain times or ports to try and evade inspection. In a partnership with border-area law enforcement agencies and CBP, we include these heuristics in the MI formulation and identify suspect vehicles using large-scale, real-world data collections. Statistical tests and selected cases judged by domain experts show that the heuristic-enhanced MI performs significantly better than classical MI in identifying pairs of potentially criminal vehicles. The techniques described can be used to assist CBP agents perform their functions both efficiently and effectively.", "pred_label": "__label__POS", "pred_score_pos": 0.8175767660140991}
{"content": "People often suggest one role of a leader is to convince people to do something.\nI disagree.\nPeople seem to associate the act of convincing with the outcome they want. If convincing worked as people wanted, I would associate them too, but I see it work differently in practice.\nIf someone disagrees with you, using logic to convince someone still depends on your premises. So if the person doesn’t agree with you, you have different premises. They’ll see your attempts at convincing as imposing your values on them and push back, leading you to convince more, and so on. Argument ensues.\nWhen people agree there’s no point in convincing either since you already agree. Trying to use logic sometimes provokes argument even when someone agrees.\nIf you think of convincing as a way of influencing and persuasion, you’re making yourself ineffective.\nYou\nare leading them, just rarely where you meant to. You’re leading them to argue with you. If you get annoyed at them for arguing with you, you missed your role in provoking the debate. My model for convincing: It’s a synonym for “provoking an argument”\nI’ve adopted a model for the act of convincing as a synonym for “provoking an argument.” Sometimes the model oversimplifies, but rarely. So when I catch myself thinking I’ll convince someone of something, I think to myself, “do I want to argue with this person and risk alienating them?”, because that’s the usual outcome.\nThen I work on my other skills of influence, persuasion, and leadership.\nRead my weekly newsletter\nOn initiative, leadership, the environment, and burpees", "pred_label": "__label__POS", "pred_score_pos": 0.5699577331542969}
{"content": "In this issue of\nAnesthesia & Analgesia, 3 articles highlight the importance of respiratory monitoring. The Obstructive Sleep Apnea (OSA) Death and Near Miss Registry examined OSA-related associations with death and brain damage. The PRODIGY Risk Prediction Model utilized continuous oximetry and capnography monitoring to identify 5 variables strongly associated with opioid-induced respiratory depression. Finally, investigators explored the external validity of the commonly used STOP-BANG questionnaire, as a screening tool for OSA. This infographic highlights the need to carefully identify patients at risk for respiratory depression, who should then be closely monitored. The reader is encouraged to review the cited articles for a better understanding and thorough discussion of these findings. REFERENCES\n1. Bolden N, et al. Postoperative critical events associated with obstructive sleep apnea: results from the Society of Anesthesia and Sleep Medicine Obstructive Sleep Apnea Registry. Anesth Analg. 2020;131:1032–1041.\n2. Khanna AK, Bergese SD, Jungquist CR, et al. Prediction of opioid-induced respiratory depression on inpatient wards using continuous capnography and oximetry: an international prospective, observational trial. Anesth Analg. 2020;131:1012–1024.\n3. Seguin L, Tamisier R, Deletombe B, Lopez M, Pepin J-L, Payen J-F. Preoperative screening for obstructive sleep apnea using alternative scoring models of the sleep tiredness observed pressure-body mass index age neck circumference gender questionnaire: an external validation. Anesth Analg. 2020;131:1025–1031.", "pred_label": "__label__POS", "pred_score_pos": 0.6178073883056641}
{"content": "Governor Lamont Encourages Participation in Statewide Vita Program to Combat Financial Insecurity During Covid-19 Pandemic\nProgram Provides Free Assistance to Low-Income Families with Filing Documents Needed to Receive CARES Act Funds and Pandemic Unemployment Assistance\nBy Tribuna Staff | Translated by Jamal Fox & Alisson Ziza\n(HARTFORD, CT) – Governor Ned Lamont announced, on June 22, his support for the Volunteer Income Tax Assistance (VITA) Program and its statewide expansion. The program provides free help for Connecticut’s low-income and ALICE families to file tax returns, allowing them to receive tax credits and coronavirus economic impact checks and to file for Pandemic Unemployment Assistance (PUA) benefits. All residents making up to $56,000 in income are eligible for the services. Administered by the Connecticut Association for Human Services (CAHS), the virtual VITA program is the first IRS-approved end-to-end digital portal to carry out these services, allowing it to rapidly scale operations statewide.\nResidents can access the full Virtual VITA services online at www.cahs.org/covid_relief. Residents can also dial 2-1-1 to find the nearest in-person VITA service site or the nearest virtual VITA portal, which offers computers for residents to log on and submit their claims. VITA works with municipalities and local community groups to provide service and accommodate residents across the state.\nEconomic impact payments available through the Coronavirus Aid, Relief, and Economic Security (CARES) Act of up to $1,200 for individuals or $2,400 for married couples, and up to $500 for each qualifying child are only available to those who have filed a 2018 or 2019 tax return, so virtual VITA opens the door for residents who don’t normally file a tax return to receive sorely needed financial support.\nSince the start of the COVID-19 crisis, beneficiaries of VITA’s tax filing service have received an average of approximately $3,000 from stimulus checks and tax credits such as the Earned Income Tax Credit and the Child Tax Credit from filing their tax returns. Those whom VITA has also helped file for unemployment benefits will receive average additional benefits of approximately $20,000 during the year. In total, VITA has delivered approximately $30 million this past year in funds received for its beneficiaries in Connecticut.\n“Many Connecticut families deeply affected by the COVID-19 crisis are unfortunately not receiving the financial support they are entitled to by the CARES stimulus, Pandemic Unemployment Assistance, or other government programs,” Governor Lamont said. “I applaud the work that VITA is doing to get our citizens the financial help they need and deserve, and our state is are committed to supporting the efforts of this important organization to connect with and assist eligible Connecticut residents.”\nCAHS has been supported in its expansion by the philanthropic organization 4-CT, which was created with the express purpose of providing emergency assistance to the state’s residents during the current pandemic.\n“VITA and CAHS have proven to be an incredibly dynamic partner in pandemic support efforts,” Ted Yang, CEO of 4-CT, said. “Few solutions empower individuals more in accelerating the pace of the government’s response to layoffs and loss of income that we’ve been seeing across the country. 4-CT will continue to work helping the state get through the COVID-19 crisis as securely as possible.”\n“We appreciate the support that Governor Lamont’s administration and 4-CT have provided and are proud to offer this critical service to families in our community at a time when they need our support the most,” John Merz, CEO of CAHS, said. “We look forward to continuing to serve the population of Connecticut and getting financial resources to those that need it the most as quickly as possible.”\nConnecticut residents who have not filed a 2019 tax return or who have become unemployed but have not yet filed for Pandemic Unemployment Assistance should visit the CAHS website to learn if they are eligible and register for VITA’s free assistance. VITA also recently announced a Referral Incentive Program, whereby philanthropic organizations within Connecticut can receive cash bonuses for referring eligible VITA beneficiaries who successfully complete the program.\nVITA estimates that as many as 140,000 people across the State of Connecticut may be eligible for some type of cash benefit from the government. The deadline for filing tax returns has been extended to July 15, 2020, and the deadline for applying for CARES stimulus funds is October 15, 2020.", "pred_label": "__label__POS", "pred_score_pos": 0.6909730434417725}
{"content": "Noida: Residents hassled due to distant vegetable market at Sec 62 Noida: Despite a strict advisory to avoid coming out unnecessarily during the ongoing Covid-19 pandemic, residents of around 20 residential societies in Sector 62, Noida, have to walk down around a mile of distance to buy vegetables from a local mandi.\nThey are doing so since the time local police acted on complaints of valuable snatching from residents. They restricted entries of vegetable vendors on roads between these societies considering safety and security of residents. But this has created a new problem for them especially during the challenging time, residents complained.\nThey said that though they appreciate the action taken for controlling incidents of valuable snatching. But it failed as there is hardly any control on these incidents. Moreover, the residents are going through huge inconvenience as they have to cover a distance of around a mile for buying vegetables.\nGulshan Dhamija, a vigilant citizen said, “It is safe to stay indoors during the ongoing challenging time but residents haven't any alternate option rather coming out and walking down to the local mandi for meeting daily needs of buying vegetables.”\n“We have heard a lot about the Noida Authority’s strict attempts to implement vending zone policy in the city. But it is not visible in this sector. The authority has not even installed any sign board indicating that the place is reserved for vendors only,” he added.\nThe problem can be mitigated for residents if the authority takes measuring steps for enforcing the policy on the ground. Dhamija said, “If the authority allocates space to vendors and ensures that they are coming to their designated space for selling vegetables in the identified vending zones, the problem would be solved for a long time.''\nHe has consistently been following the issue with concerned officers but they are yet to take action. He said, “Forget the action, they don't even bother to respond to the formal communication made to them.”", "pred_label": "__label__POS", "pred_score_pos": 0.7757658958435059}
{"content": "Build a positive, accountable classroom environment with restorative discipline!\nWith restorative discipline, schools move beyond punitive approaches to shared expectations for learning and behavior. Used together with\nThe School Leader'' Guide to Restorative Discipline, this teacher's guide shows how to create a welcoming and responsible community within your classroom, contributing to a consistent, schoolwide approach to discipline.\nAuthors Luanna Meyer and Ian Evans offer field-tested strategies that transform classroom dynamics. Topics include:\nA step-by-step approach to introducing restorative discipline in your classroom Developing peer support and group problem-solving among students, including preventing and stopping bullying Collaborating with administrators and colleagues on schoolwide behavior expectations Partnering with families and neighborhood organizations to support positive student conduct Managing effective individual interventions with students, including four key principles for success\nThis comprehensive guide helps teachers introduce and sustain a proven approach to discipline, preparing students for achievement in school and life.", "pred_label": "__label__POS", "pred_score_pos": 0.9957372546195984}
{"content": "Anxiety in Children\nParents often inquire if theirchildren with anxietywill outgrow theiranxietyor if they will get worse over time. Some anxiouschildren, if encouraged to face their fears, develop adjusting skills on their own as they mature. In that sense, they do surmount theirfears.On the other hand,children with anxietythat avoid theirfearscan become quite handicapped by them. With prolonged aversion of age-appropriate activities, valuable skills are lost and the children with anxietybecome increasingly dependent on the few people to whom they relate. Often,family conflictsresult due to poor coping skills. With increased family conflict and diminished ability to keep up at school and with peers, theirself-esteemplummets.\nFortunately, mostchildren with anxietycan overcome theirfearsby gradually facing them. Each time afeared situationis faced, the child becomes a little less sensitive to it. After a childis repeatedly exposed to the apprehensive situation and is helped to successfully master his or heranxiety, the fight-or-flight reaction to that situation will disappear .\nOver a lifetime,anxietytends to come and go in those people who are susceptible to it. Exacerbations tend to happen when supports are lost or a new stressor is faced. For example, the expectation forchildrento behave more autonomously atadolescencecan be difficult for asensitive childwho has previously relied a great deal onparental support. However, for a child that has learned adjusting skills, this difficulty is not a cause fordespair. Instead, it is a signal that previously learned coping skills need to be reviewed, and a few new ones may need to be added. Each time a new situation is mastered, confidence builds, allowing thechildto face new challenges and live aproductive, fulfilling life.\nDeciding on the best method for inducing yourchildren with anxietyto face what is feared may require some thought. As a rule, whatever works and does not harm is best. If your childlacks the skills needed to face what is feared, some training by a psychologist in those skills may be needed before exposing thechildto what isfeared. For example, a chronically shy childthat for years has not communicated with friends may lack thesocial skillsto do so. Once the required skills have been taught, yourchildmust face what is feared through repeated exposures to it.\nBOLA TANGKAS {youtube|100|campaign}", "pred_label": "__label__POS", "pred_score_pos": 0.7237430810928345}
{"content": "Paper Title Technological Aspects Related to Prebiotics Inclusion in the Macedonian Dairy Industry Abstract Probiotic dairy products have been defined as “food containing live micro-organisms believed to actively\nenhance human health by improving the intestinal microbial balance”. This study was carried out to evaluate the growth and\nviability of probiotic bacteria Bifidobacterium bifidus in natural set-yogurt during the period of 28 days (0, 1, 7, 14, 21, 28\ndays). Three series of fermented cow’s milk have been taken, prepared in three variants as follows: the first variant (B) was\nprepared by the addition of the prebiotic Fibregum B, the second variant (P) with the addition of a prebiotic Fibregum P and\nthe third variant of the fermented milk without prebiotic, served as the control variant (K). The dynamic of probiotic’s\nbacteria growth and development was determined using a colony reader (pbi international F4). The count of probiotic\nbacteria Bifidobacterium bifidus was higher in natural set yogurt with prebiotic inclusion compared to the control variant\nwithout prebiotics. It has been concluded that the development of bacteria depends on the conditions and stage of production\nand the type of prebiotic.\nKeywords - prebiotic, Bifidobacterium bifidus, natural - set yogurt, dynamic.", "pred_label": "__label__POS", "pred_score_pos": 0.8829890489578247}
{"content": "My parents are celebrating their 59th wedding anniversary this month! As I sit in their living room and listen to their familiar banter, I wonder what it is that has kept them together so long? What is it that allows love to grow within relationship and more importantly, within us individually?\nA warm and loving relationship is one of the most rewarding experiences in life; embracing a long-term commitment, even more so. To get to know and accept our partner’s strengths and weaknesses in a most intimate way, is challenging and fulfilling at the same time. It is where the deepest learning of ourselves takes place and where our creativity may flourish. Creativity sits in the heart of love and enables us to persevere the difficult times that inevitably happen; creativity works within the relationship to keep it alive and gratifying; creativity dances within the framework of relationship to help us remain whole and true to ourselves.\nThe love that often receives the least notice is Self-love. Spending time reflecting on the inner parts of ourselves that take away from living fully in love, and releasing from the source, takes commitment. The Self-awareness required to know when the unconscious voices of unlove take over and how to replace them with kindness and compassion can be arduous at times. Without creativity this process may become overwhelming or at worst, not happen at all.\nOne of the ways I uncover unconscious thoughts is when I have judgment for those around me. When I hear the voices in my head being critical, angry, discriminating, self-righteous, or feeling judged by another, I spend time noticing how I may change my outlook. Often the deeper meaning of what I am feeling is where, in my life, I am critical of myself. By identifying where the source of my harsh criticism lies within, I begin to see a situation differently. This is where creativity allows expansion beyond the old voices, perceptions and patterns. Creativity engages new parts of my being to move out of the critical and into compassion.\nHealing our internal relationships is essential to becoming more Self-aware. When accessing creativity in the Self-awareness process, the outcome of love is inevitable. Creativity holds curiosity, inventiveness and inspiration, all key elements in realizing and maintaining love. Love provides safety for creativity which inspires more creativity which inspires more love. As we heal our internal relationships and nurture our inner love and creativity, more love and compassion flows in our external relationships.", "pred_label": "__label__POS", "pred_score_pos": 0.5595898628234863}
{"content": "A case of Influenza A (H1N2)v was detected in Alberta in October.\nA statement from the Province of Alberta notes that one confirmed cases of H1N2v was detected in mid-October after a patient felt flu-like symptoms and received medical care.\nSee also:\nThe symptoms were mild and the patient recovered quickly the release states.\nThe Province of Alberta’s website notes that H1N2v can result in mild respiratory illnesses, along with symptoms similar to the seasonal flu.\n“There is no evidence at this time that the virus has spread further,” states Dr. Keith Lehman, chief provincial veterinarian, in the release.\n“Health officials, in conjunction with Alberta Agriculture and Forestry, have launched a public health investigation to determine the source of the virus and to verify that no spread occurred. The Government of Alberta will continue working closely with Alberta Health Services, the Public Health Agency of Canada and other partners across Canada.”\n1/3 A single case of variant influenza A(H1N2)v has been reported in Canada. This is a rare type of flu in humans, typically acquired from exposure to infected pigs and not known to spread easily from human to human. https://t.co/exhH1UTGpr\n— Dr. Theresa Tam (@CPHO_Canada) November 4, 2020\nUnlike another flu variant H1N1 (AKA the Swine Flu) that saw its own pandemic back in 2009, the variant Influenza H1N2 has only seen 27 cases reported globally since 2005, notes the statement, with this recent case marking the first ever seen in Canada.\n“H1N2 is not a food-related illness. It is not transmissible to people through pork meat or other products that come from pigs and there is no risk associated with eating pork,” the statement reads.\n“We will keep Albertans informed of the outcomes of the public health investigation.”", "pred_label": "__label__POS", "pred_score_pos": 0.5212695002555847}
{"content": "GasNaturally Gas Appliances Brochure\nA balanced energy mix is key to achieving the EU climate objectives – including net-zero GHG emissions in 2050 – in a resilient, efficient, and affordable way. The presence of renewable and decarbonised gases – biomethane and hydrogen from power-to-gas, pyrolysis, and steam methane reforming with carbon capture and storage – will increase towards the middle of the century. As each energy source has intrinsic advantages and challenges, the overarching need is to combine and optimise available sources in ways that meet the different energy demands of each country, city, district, and building. With a focus on the evolving role of gas, this brochure explores scenarios for technology and market development in residential, commercial, and industrial sectors.", "pred_label": "__label__POS", "pred_score_pos": 0.749723494052887}
{"content": "Introduction: The benefits of clinical trials registration include improved transparency on clinical trials for healthcare workers and patients, increased accountability of trialists, the potential to address publication bias and selective reporting, and possibilities for research collaboration and prioritization. However, poor quality of information in registered records of trials has been found to undermine these benefits in the past. Trialists' increasing experience with trial registration and recent developments in registration systems may have positively affected data quality. This study was conducted to investigate whether the quality of registration has improved. Methods: We repeated a study from 2009, using the same methods and the same research team. A random sample of 400 records of clinical trials that were registered between 01/01/2012 and 01/01/2013 was taken from the International Clinical Trials Registry Platform (ICTRP) and assessed for the quality of information on 1) contact details, 2) interventions and 3) primary outcomes. Results were compared to the equivalent assessments from our previous study. Results: There was a small and not statistically significant increase from 81.0% to 85.5% in the percentage of records that provided a name of a contact person. There was a significant increase from 68.7% to 74.9% in the number of records that provided either an email address or a telephone number. There was a significant increase from 44.2% to 51.9% in the number of intervention arms that were complete in registering intervention specifics. There was a significant increase from 38.2% to 57.6% in the number of primary outcomes that were specific measures with a meaningful timeframe. Approximately half of all trials continued to be retrospectively registered. Discussion: There have been small but significant improvements in the quality of registration since 2009. Important problems with quality remain and continue to constitute an impediment to the meaningful utilization of registered trial information.", "pred_label": "__label__POS", "pred_score_pos": 0.9995044469833374}
{"content": "Updated: 2 days ago\nWould you consider mentoring me?\nIsn't that one of the most nerve-wracking questions a Christian woman could\nanother woman?! ask\nOR... is it the scariest question\nto be asked??\nGrowing up in the church, I was significantly blessed to experience the guidance of godly men and women, as they taught me Sunday school, Pioneer girls, took us on mission trips, and equipped us for ministry through youth ministry teams and summer camp.\nIn my university days, I moved, found a new church in the city and came across Christian books that imparted truth to my life. Then, marriage, and a move to Africa, found me sitting under amazing leaders and teammates, who encouraged my theology and guided the practical challenges of crossing cultures.\nAs I thought about all the people who played a deeply treasured role in my growth and development, I discovered a list that held many names.\nThese relationships represent connectedness, a fertilizer for the season, to nourish, strengthen, and lead me, through seasons of need, drought and uncertainty.\nAs I have been poured into by others, it is my own joy and privilege to share in the journey of others; being blessed with opportunities to walk alongside a younger woman, to hear her story, to encourage her heart and invite conversation that leads us to Jesus. You might think that the mentor is the one who does all the blessing, but I have found that these women have made a big impact on my life, in how they have persevered, demonstrated resolve, and sought Jesus through tough times; they model the Gospel to me.\nBut, moving back to the question, I think many women in the church fear this question, this endeavour of mentoring. Some of it, I think, is related to fears:\nwhat will I say? what will I do? Sometimes the nervousness is related to insecurities, as if there is a 'good enough' model to reach before we are qualified to mentor. Perhaps there's also a fear that entering into a mentoring relationship is a lifelong commitment.\nThis is where\n\"Growing Together\" comes in. Written by Melissa Kruger, the purpose of this book is to provide \"a hands-on tool that a mentor and mentee can use together as a springboard for mentoring discussions.\"\nShe encourages us in the first two chapters of the importance of the mentoring relationship, and to clarify the expectations of what times together look like.\nThe next 9 chapters highlight different topics of Christian living, such as church, prayer, family and, temptations, to facilitate the conversation between the mentor and mentee. At the end of each chapter, you'll find a handful of questions that you can discuss, with the added challenge of considering an area of change.\nIn a nutshell, this resource will guide you to mentor another young woman, providing conversation starters and accountability. Yes, you will need to play your part, but no longer is there a reason to feel lost or an excuse that you don't know how!\nI give it 5 stars. This is a great resource for all Christian women! I say\nall to remind us that we all are exhorted to mentor. It's not a responsibility for the 'gifted' or the 'mature' it is for the regular women who follow Jesus, like you and me.\nI lovingly challenge you to buy\ntwo copies of this book and ask the Lord who you can share this journey with! **Thank you to Crossway for the complimentary copy of this book and the opportunity to post an honest review!", "pred_label": "__label__POS", "pred_score_pos": 0.5973790884017944}
{"content": "Boy Voice and Choice (2019-20)\nAs technology and information rapidly change, so too do the challenges our students encounter. How do we as educators encourage them to boldly and creatively adapt to these challenges? I believe the answer is to develop agency within our students by highlighting for them the value of their voices and ideas in contributing to solutions.", "pred_label": "__label__POS", "pred_score_pos": 0.9998766183853149}
{"content": "Strong partnership working in Cheshire West and Chester has been praised by Ofsted and other inspectorates in a Joint Targeted Area Inspection focusing on neglect.\nOfsted, HMI Probation, HMI Constabulary, Fire and Rescue Services and The Care Commission found Cheshire West and Chester had a “clear and collective commitment” to improving responses to children who suffer neglect.\n“Collaborative and well-coordinated work at a strategic level to address neglect has been in place for some time and the impact is evident in effective partnership working at an operational level,” said the report. “This is resulting in many children receiving a timely and appropriate response to reduce risk and the impact of neglect.”\nMany professionals in CWAC receive good-quality supervision and have access to a range of training on neglect, the report finds. A wide range of agencies are involved in LSCB audits and the findings are widely disseminated across partner agencies, leading to improvements in practice.\nOther key strengths highlighted include:\nThere is clear evidence, across many partners, of approaches that support the early identification of neglect. The large majority of referrals where risks to children suffering neglect are first identified are dealt with in a timely manner. Social work assessments include appropriate input from a range of agencies, the identification of key risks and protective factors, and a clear rationale for the outcome. The LSCB and the local authority have worked collaboratively to develop a suite of neglect indicators. Senior managers in children’s social care have developed an environment where social workers can provide a high-quality service to children and their families. The local authority demonstrates its commitment to children and families through significant investment in staff to ensure a well-qualified and skilled workforce\n“There is strong and very effective leadership in children’s social care, and a clear approach to developing innovative and child-focused practice to support children living with neglect,” the report added.\nThe report highlighted that there are a number of further ways in which systems for accessing information and communicating information between agencies could be improved in the early stages of the identification of risk of neglect to children. In addition, the outcome of early help assessments is not routinely shared with probation services.\n“A key area for improvement is the timeliness and rigour of evaluating the progress of multi-agency work to reduce risk and the impact of neglect on children. In a small number of cases, there was drift and delay in ensuring that the plans to reduce neglect were making sufficient progress and meeting children’s needs,” the report added.\nInspectors also noted that there is no data or performance management information relating to neglect held in the police protection unit and this would assist the force to understand performance, demand, resource allocation and impact on outcomes for children and young people.\nThe report concluded that the director of children’s services should now prepare a written statement of proposed action, responding to the findings outlined in the report.", "pred_label": "__label__POS", "pred_score_pos": 0.5110241174697876}
{"content": "MENAP and the rise of person-centric measurement not audience measurement\nAbstract:\nWith the advent of more robust digital platforms, marketing is moving from audience- and channel-based planning, to person-centric marketing. With this shift in focus, tools to quantify and analyse the behaviours at the individual level are required. However, previous research shows that consumers, when compared by age or gender, have fundamentally different media behaviours. These differences are critical to marketers who aim to tailor their plans and ensure their target audience receives the right messages, via the right touchpoints, at the right time. This presentation will highlight how, by using data capture and processing technologies, insights can be utilised to provide a complete picture of the complex cross-screen, cross-device behaviours of today's digital consumer.\nVideo This could also be of interest", "pred_label": "__label__POS", "pred_score_pos": 0.8626989126205444}
{"content": "Tea Board has invited Expression of Interest (EOI) for the proposed crop insurance scheme for small growers in which National Insurance Company has emerged as the sole bidder. The Tea Board had relaxed some terms in the crop insurance scheme following very poor response to the first round of bidding in November 2016. The cover would come into force when the loss is 15% as against the earlier 10%.Several Insurers dropped out of the race leaving the State owned firm as the lone bidder. In the initial rounds several private sector companies had participated. After internal consultations and a nod from Tea Board chief Santosh Sarangi, it was decided to proceed with a single bidder as it was a PSU and open the financial bid (the premium that would have to be paid). A pilot would be run in three districts in Assam (Golaghat), West Bengal (Jalpaiguri) and Tamil Nadu (Conoor) for one crop cycle spread over two years commencing 2016-17 and covering 57,355 small growers. At the ratio of 75:15:10 the cost is to be shared between the centre,the State Governments and the growers. The scheme for tea — Revenue Insurance Scheme for Plantation Sector for Tea — aims to protect growers from the risks of yield loss due to adverse weather and income loss due to falling prices. The emerging force in the Indian tea Industry is now the small tea growers which accounts for more than 35% of the output. Due to hailstorms,excess rainfall and pest attacks,several crops has been damaged and this is witnessed by small tea growers.", "pred_label": "__label__POS", "pred_score_pos": 0.5834407806396484}
{"content": "Chancellor\nRishi Sunak has hailed the commencing of ‘a new chapter’ for the UK’s financial sector following Brexit.\nDescribing it as one of the UK’s ‘most innovative sectors’, the UK government underlined that legislation and decisions will be led by what is best for the sector.\nAs well as this, he also outlined a new invigorated focus on digital currency, with the issuing of the UK’s Sovereign Green Bond, becoming the first country in the world to make TCFD-aligned disclosures mandatory, reviewing the UK’s listings regime to attract the most innovative firms, and leading the global conversation on new technologies like stablecoins and Central Bank Digital Currencies.\nSunak stated: “We are starting a new chapter in the history of financial services and renewing the UK’s position as the world’s pre-eminent financial centre. By taking as many equivalence decisions as we can in the absence of clarity from the EU, we’re doing what’s right for the UK and providing firms with certainty and stability.\n“Our plans will ensure the UK moves forward as an open, attractive and well-regulated market, and continues to lead the world in pioneering new technologies and shifting finance towards a net zero future.”\nSunak is seeking to strengthen the UK’s position as a frontrunner in terms of the financial sector and specifically within financial tech.\nWith fresh advancements in new technologies such as stablecoins – privately-issued digital currencies – potentially transforming the way people store and exchange their money, making payments cheaper and faster.\nTo harness the potential benefits of stablecoins, whilst managing risks to consumers and financial stability, the Government will propose a regulatory approach for relevant stablecoin initiatives that ensures they meet the same minimum standards we expect of other payment methods.\nFurthermore, the prevalence and significance of digital currency has been further grown as commerce and the economy has endured the turbulence of the coronavirus pandemic. It has led to less cash-carrying and far more reliance and desire to embrace digital currency and transactions.", "pred_label": "__label__POS", "pred_score_pos": 0.5697009563446045}
{"content": "Abstract\nThe electronic properties of two-dimensional (2D) materials, like graphene, are of considerable fundamental interest. This paper describes how physically adsorbed films probe these properties. The cases of an ideal 2D free electron gas and graphene are examined, with explicit results found for an adsorbed He film. In the free electron case, the scattering is proportional to the 2D structure factor of the film. Results are presented for He on graphene and the free electron gas in both the low coverage and fully commensurate limits.\nAll Science Journal Classification (ASJC) codes Atomic and Molecular Physics, and Optics Materials Science(all) Condensed Matter Physics", "pred_label": "__label__POS", "pred_score_pos": 0.6186320781707764}
{"content": "Leading change through a clear and compelling vision, rather than forcing, controlling or problem solving is the Transformational Leadership Principle upon which we base our work. All though this strategy works, it is not often used.\nEvery solution or skill set we utilize is different depending on what your needs are, what your budget is and what your willingness is to engage in this transformational process.\nThis is where total transformation occurs; leaders emerge and the status quo is challenged. Successful individuals and organizations are strengthened and propelled forward as teams unite under a common mindset, language and vision. We provide the tools and expertise that enable Transformational Leadership to occur every day.\nLeading Change is a leadership development program that supports participants in their transformation to becoming a leader, and teaches participants how to deliberately access and shift into a state of leadership.\nThis management training course is designed to transform your ability to engage others by moving you from a command-and-control model of communication to one of collaboration and accountability.\nA coach engages and facilitates focused dialogue, challenges, inquires, cajoles, inspires, provokes, offers support, and collaborates with their clients on business issues and goals, while focusing on the personal development of the client.", "pred_label": "__label__POS", "pred_score_pos": 0.9989012479782104}
{"content": "When I flew into the airport and saw the palm trees, they looked like home, but odd, almost artificial, pseudo-tropical — they weren’t pines.\nI had spent the morning driving through Montana’s rolling hills, ogling the lovely farms, the sparklingly clear rivers, the pines wandering along the rivers, the pines strolling up into the hills.\nBut now I was back home. As we drove from the airport, into San Diego, I still had a smile on my face.\nI love airplanes, I love travel, I love cities — their museums and restaurants –and I am smitten with hills, rives and pines. New places change how we see, allowing us the luxury of contextualizing love — and beauty. I love a new place, anchored in eating, sleeping, wandering, exploring, fishing, hiking, slouching and smooching.\nIt brings up the question, how does one enjoy life? How does one really mouth it, chew it, savor it, kiss it, dive down deep into the cold, clear, refreshing liquid-rush of it?\nBy sloshing in it!\nIn Montana, on the Blackfoot River, I stood stiff-legged in the front of the boat, locking my leg into the curved plastic of the hull and cast my dry fly to the right bank. The boat sloshed, I rocked back and forth, Matt yelled “Mend,” I did, and an eighteen inch Cutthroat trout boiled to the surface, took my fly right off the top of the boiling water, and dove.\nI reared back on the fly rod, it bent toward the water, and the Cutthroat took off like crazy toward the far bank. Beautiful! Thrilling! Perfect!\nThat night when we got off the river my back hurt like crazy. It didn’t matter. I had sloshed in it, in the river, in life. I had done what it takes to receive the beauty. I had placed myself in a posture to receive.\nThis is how you do it, but something else is required too.\nYou have to prep like crazy!\nFor the last year before my Montana trip, I had worked like crazy at my job, and made and saved the money to go. And then I had thought and planned and talked and arranged. I had practiced with my fly rod on my front driveway, casting to imaginary fish in a concrete river. I had made an arrangement with my friend, I had paid my money, I had made the long trip, I had hired the skilled guide, had gotten in the boat, cast the rod and I had mended the line.\nIt takes an effort to enjoy life, and sometimes some pre-work. But when you do that, you get it — some pleasure, a Cutthroat trout, some loveliness, a bit of the gorgeous whip and womp and woof of the wonders.\nThat day, as we rocked down the river, we watched a bald eagle soar overhead, perused a black bear as it wandered along the bank, peered at a herd of elk on a far hill and watched Mayflies dance in a tall, white column above the river.\nWe were immersed in the Blackfoot and the ecosystem of the Backfoot — the sparkly white, rapids, the bumpy, rocky bottom, the cool rain that spotted our coats and brought a fresh, damp fragrance to our senses, the deep fish-filled water along the banks — the gorgeous speckled shinning rainbow trout, brown trout and Cutthroat Trout that we caught and released that day.\nThis is how you do it, how you enjoy it.\nLife is so good, from time-to-time, and we can enjoy it, the columns of Mayflies, and then again, the churning fish-filled rivers, when we get a chance, the lovely pines, if we put ourselves out in it — the soaking rain — and do the work, and make a choice to get up and get out, and slosh in it.", "pred_label": "__label__POS", "pred_score_pos": 0.6806465983390808}
{"content": "ALDHAHERI 2\nMajedAldhaheri\nCOM122NNS#3\nDr.Lindsey Ives\n09.22.2015\nAcademicWriting Development Strange Lands\nMasteryof a new language is very complex. According to McCarthy, academicwriting development is contextual. This means that individuals learnhow to write within an academic community discourse by learning theprinciples and rules that guide communication in that particulardiscourse. Thus, transiting from one academic discourse to another islike to get into a strange land. This paper supports McCarthyargument that entering a new academic discourse community andperfecting its written language is like learning a language in aforeign country.\nMcCarthyargues that languages processes and speaking is largely influenced bythe social and cultural contexts in which they occur. Use of languageoccurs within a special community and aims at achieving a meaningfulsocial function. As a result, people within the same social contexthave similar ‘ways of speaking’. This is because the social andcultural context defines the acceptable linguistic and intellectualprinciples that govern speaking and social communication. The abilityto perfectly use these rules, largely unconsciously, results intocommunication competence. Similarly, communication through writtenmeans takes place within a particular community discourse. Effectivewriters put into consideration the details that are important for themembers of a specific community discourse. Based on thatunderstanding, McCarthy argues that when a student enters aparticular academic discourse community, they learn the rules andprinciples of communication in a similar way an individual learnswhen entering a foreign country (McCarthy, 234). Cultural factorshave a huge impact on communication. For example, cultures define howan individual addresses an elder or a senior person. Culture alsoinfluences other essentials of communication such as eye contacts andfacial expressions. The principles that guide communication within aparticular community discourse are learned progressively over time.\nAslearners advance from one level of study to the next, they master theprinciples and rules of communication that are acceptable within thatacademic discourse. The mastery of these principles and thus thewriting competence is evaluated based on the standards within thecommunity discourse. It is essential to note that even innon-academic writing there are complex norms and principles thatmust be learned, both tacit and explicit, for a writer to besuccessful within that discourse. Learning how to write within aparticular academic discourse can be compared to learning a newlanguage within a new cultural and linguistic background. Writing inthe academic discourse involves the teacher and the learner as wellas other essentials such as the subject matter, sequence of actionsand learning activities, and the structure of the task. Additionally,the academic discourse is not viewed from the school context, butrather from the professional conventions in that discipline andintellectual norms. As learners progress in their academic andprofessional life, the overlapping principles of academic writinginfluence the way students think, write and interact with theirteachers and other students ((McCarthy, 235). Progressively, thisbuilds the notion of what it means to be a nurse, a literary critic,psychologists, a scientist or a member of any other profession.\nInconclusion, in the same way learning how to speak takes place in aparticular context and is influenced by communication norms andprinciples, academic writing also occurs within a particular context.Therefore, learning the communication norms in a foreign country canbe used to understand how individuals learn how to write effectivelyin a new academic discourse. In the same way individuals perfect anew language in the cultural context progressively, learners alsolearn how to write in an academic context progressively.\nWorkCited\nMcCarthy,Lucille Parkinson. \"A Stranger in Strange Lands: A CollegeStudent Writing Across the Curriculum\",\nResearchin the Teaching of English,21(3) (Oct., 1987), p 233-265.", "pred_label": "__label__POS", "pred_score_pos": 0.6040041446685791}
{"content": "Process bottlenecks had led to significant delivery delays and cost overruns at the Singapore MRO plant of a leading aerospace manufacturing company with global service operations.\nThe client chose Infosys as their partner to address the challenges of delayed production, high costs and low productivity. Infosys’ initial assessment enabled an end-to-end connected factory solution, from selecting the right sensors to ensuring the right data elements were available for downstream intervention.\nKey Challenges Ready to experience? OEE and condition monitoring for shop floor machines Production cost optimization through intelligent scheduling Energy and Waste Management\nEnabled schedule adherence and cost optimization\nProduction visibility increased from 2 days to 21 days\nCustomer delivery adherence increased by 5% in the first six months\nOperational effectiveness efficiency (OEE) increased from 57% to 70%\nReduced revenue hours per par, from 0.80 hours to 0.75 hours, in the first 12 months\n~10% decrease in solid and liquid waste from machines", "pred_label": "__label__POS", "pred_score_pos": 0.9882811307907104}
{"content": "All honey is yummy, but raw buckwheat honey is extra special. Registered dietician Ashley Koff describes this delicious product in this video.\nRaw buckwheat honey isn't just a sweet treat. In this video, integrative medicine specialist Tasneem Bhatia, MD, explains how it can fight a common illness.\nContinue Learning about Dietary Supplements\nImportant: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.", "pred_label": "__label__POS", "pred_score_pos": 0.9912402629852295}
{"content": "Recently, a past client came to our offices asking, “How often can I file for bankruptcy?” Some may find this surprising. We may not see it on Wall Street, but the U.S. economy has struggled for a long time. So, it is not uncommon for a person to go through cycles of doing well, only to have their rug pulled from under them. While at one time multiple bankruptcies in a lifetime were unheard of, today it is not surprising. Nevertheless, the law does place some limits on filing multiple bankruptcies.\n1.\nFiling a Chapter 7 after a Chapter 7 – If a Chapter 7 bankruptcy resulted in a discharge, you must wait eight years from the date you filed last to then file Chapter 7 again.\n2.\nFiling a Chapter 13 after a Chapter 13 – If a discharge of debts occurred with a Chapter 13, you cannot receive another Chapter 13 discharge until after two years of the first filing.\n3.\nFiling a Chapter 7 after a Chapter 13 – If the initial discharge came due to a Chapter 7 bankruptcy, you are not eligible for a Chapter 13 for at least four years.\n4.\nFiling a Chapter 13 after a Chapter 7 – Here, you must wait six years from the date of the first filing before a succeeding Chapter 7 petition. However, this does not apply if all the unsecured debts are paid or if you paid 70 percent of the unsecured debt and the court determines you gave your best effort to a plan proposed in good faith.\nRegardless, there are some additional restrictions. The court may obstruct you from filing another case for a particular time. Typically, this occurs if the initial petition was dismissed with prejudice. In many cases, it is typically a 180-day bar because either you failed to obey the court’s order or they believe you are in some way abusing the bankruptcy system.\nDo you have questions? Please contact us if you would like to talk about the limits on filing multiple bankruptcies.\nCan a Bankruptcy Discharge be Denied? - July 30, 2018 Why Filing Chapter 7 Bankruptcy Could be a Mistake - June 28, 2018 Discover If Bankruptcy Can Be a Blessing in Disguise - May 30, 2018", "pred_label": "__label__POS", "pred_score_pos": 0.8891693353652954}
{"content": "Oral arguments can be challenging for many lawyers, even under the best of circumstances. Add the challenge of remote communication...Read more\nIf anything is constant in today’s immigration landscape, it is that change is consistently happening. September has been no different...Read more\nCannabidiol. Tetrahydrocannabinol. These are the scientific terms for the compounds found in hemp and marijuana, respectively (thank goodness for acronyms)....Read more", "pred_label": "__label__POS", "pred_score_pos": 0.594594419002533}
{"content": "A positive outcome of the stay at home time has been a resurgence in bicycle riding.\nAre you trying to teach your child to ride so they can enjoy the thrills of bike riding too? For a child, a bicycle represents freedom.\nThe ability to get out and about on their own is a significant step in a child’s self-development. It is often a big element for their social development too.\nBeing able to ride a bike means the freedom to:\ngo out to explore rendezvous with friends exercise be independent.", "pred_label": "__label__POS", "pred_score_pos": 0.8419674634933472}
{"content": "A growth function was developed for describing the progression of shoot elongation over time. While existing functions, such as the logistic function or Richards function, can be fitted to most sigmoid data, we observed situations where distinct lag, linear, and saturation phases were observed but not well represented by these traditional functions. A function was developed that explicitly models three phases of growth as a curvilinear (exponential) phase, followed by a linear phase, and terminating in a saturation phase. This function was found to be as flexible as the Richards function and can be used for virtually any sigmoid data. The model behavior was an improvement over the Richards function in cases where distinct transitions between the three growth phases are evident. The model also lends itself well to simulation of growth using the differential equation approximation for the function.\nIf the inline PDF is not rendering correctly, you can download the PDF file here.", "pred_label": "__label__POS", "pred_score_pos": 0.9800490736961365}
{"content": "NATIONAL AMERICAN BEER DAY\nNational American Beer Day raises a glass to the rich American beermaking history and those who savor the continued traditions. Pour your favorite pint with millions who enjoy the storied brews across the nation.\nU.S. Brewing History\nBrewing beer in America begins long before Europeans arrived since Native Americans brewed beer from various ingredients. They used corn, birch sap, and water to ferment their beverage. When the first colonists arrived in Virginia, they began combining their brewing traditions with the supplies at hand – that included corn, too. Since then, brewing and brewers became a principal occupation in the colonies. Interestingly, the first white child born in Manhattan grew up to be the first brewer born in America.\nToday, the brewery established by David G. Yuengling is the oldest producing brewery in the United States. He established the Eagle Brewery in 1829. Amazingly, the brewery remains in the family to this day.\nUnlike most other breweries of the time, the Eagle Brewery survived Prohibition. In fact, very few survived. Those that did survive tried various legal and illegal tactics. In Eagle Brewery’s case, they reduced their alcohol content to within the legal limit. They also branched out. Ice cream, anyone? Yes, the Yuengling’s started a dairy. Others turned their beermaking supplies into other products. When prohibition lifted, they returned to full-fledged beermaking.\nDespite these efforts, nearly every brewer existing before prohibition dissolved. Out of just over 1,300 brewers, only about 100 remained after prohibition. Today, we recognize the names of many of those surviving breweries.\nThe skill of a brewer requires years of practice in the trade. It’s revered even. In Milwaukee, their professional baseball team is named after the brewer. In St. Louis and Denver, the stadiums are named after prominent brewers.\nMore than 2,100 breweries are manufacturing beer in the United States. They range in size from industry giants to brewpubs and microbreweries.\nAmerican Beer Facts The U.S. produced 196 million barrels of beer in 2009. Americans consume roughly 20 US gallons of beer per capita annually. In 2008, the United States ranked sixteenth in the world in per capita consumption. However, total consumption was second only to China. After Congress repealed prohibition, the industry consolidated into a small number of large-scale breweries. The majority of the new breweries in the U.S. are small breweries and brewpubs. As members of the Brewers Association, they are termed “craft breweries” to differentiate them from the larger and older breweries. Larger breweries most commonly produce the American lager. However, smaller breweries (many founded in the 1980s) produce a range of styles. Beer styles originating in the United States include: American pale ale Pennsylvania porter American IPA steam beer amber ale cream ale Cascadian dark ale. HOW TO OBSERVE #AmericanBeerDay\nEnjoy your favorite American Beer. Invite a friend or two to join you. While you’re at it, try something different. American beers offer a variety of options to choose from. Do you have a favorite brewery? Give them a shout out, too! The brewmaster deserves to be recognized. Tour a brewery to learn more. While you’re there, try a sample or two.\nNow, beer also holds great influence. If you didn’t know that, read about 5 Surprising Ways Beer Changed the World. Remember, always drink responsibly and never drink and drive.", "pred_label": "__label__POS", "pred_score_pos": 0.6640487909317017}
{"content": "After four years of deliberation and analysis, the Portland City Council adopted the Residential Infill Project (RIP) on August 12, 2020. According to the City, RIP legislation is intended to increase housing opportunities by opening up the types of dwelling units that can be constructed in residential zones that have historically not allowed them, namely those zones that allow primarily single-family residential units. Under RIP, triplexes, fourplexes, sixplexes and cottage clusters will now be allowed in many single-family residential zones they were not allowed in before. Maximum dwelling size has been reduced from approximately 6500 square feet for a single-family unit to 2500 square feet, based on the floor area ratio allowed for a typical 5,000 square foot lot in the R-5 zone. Off-street parking to accommodate the additional density has been made optional.\nThe legislation has been controversial, which is primarily why it has been under review since 2016. Critics state that it unnecessarily disrupts established neighborhoods, will lead to too much density, and exacerbates a lack of parking. RIP was adopted with only Commissioner Amanda Fritz voting “no,” because, in part, the increased density is not being funnelled to areas with supportive transit.", "pred_label": "__label__POS", "pred_score_pos": 0.608599066734314}
{"content": "COVID-19 Testing Labs: Beware of the EKRA Law\nWith demand increasing for widespread COVID-19 testing, clinical laboratories processing COVID-19 tests must be diligent in ensuring that their marketing and compensation arrangements comply with the Eliminating Kickbacks in Recovery Act (EKRA).\nSince the risk of fraud and abuse has increased during the pandemic, the U.S. Department of Justice (DOJ) has asked that all U.S. Attorney Generals work closely with their community to detect, deter, and punish those who seek to profit off the public’s fears during COVID-19. The federal Anti-Kickback Statute (AKS) has been predominantly used in recent cases of fraud from the DOJ, but now they are beginning to employ EKRA (18 U.S.C. § 220) to combat fraud as well.\nThe current enforcement climate increases the chances that the government will turn to EKRA as a prominent enforcement tool. EKRA was enacted by Congress in 2018 to stop patient brokering and kickbacks among treatment centers and testing labs involved in opioid treatment. However, the law broadly applies to all laboratories, not just those that perform testing related to substance abuse. Because of this broad application, it is imperative that all laboratories—including COVID-19 lab companies—understand EKRA and how to comply with its regulations.\nWhat is the EKRA Law?\nEnacted as part of a larger federal legislative initiative aimed at addressing the opioid crisis, the EKRA law prohibits recovery homes, clinical treatment facilities, and laboratories from accepting or paying kickbacks for referrals.\nUnder EKRA, it is a federal crime to knowingly and willfully do the following:\n● (1) solicit or receive any remuneration (including kickbacks, bribes, or rebates) directly, or overtly in return for referring a patient to a recovery home, clinical treatment facility, or laboratory; or\n● (2) pay or offer any remuneration either to induce a referral or in exchange for an individual using the services of a recovery home, clinical treatment, or laboratory.\nThose that engage in these activities face serious punishment. Breaking the EKRA law can result in fines of not more than $200,000, imprisonment of no more than 10 years, or both for each occurrence.\nEKRA and COVID-19 Testing Labs\nWhile laboratories scramble to meet the nation’s demand for COVID-19 testing—playing a critical role in the diagnosis and treatment of coronavirus—they must simultaneously remain diligent in their compliance efforts. Testing labs should evaluate their compensation structures, particularly for marketing or sales staff. EKRA includes exceptions for payments to employees but the parameters are, in some cases, applied more stringently than the safe harbors defined by the AKS. “AKS allows any payments to an employee as long the employment relationship is clearly defined,” says Managing Shareholder and health law expert Trey Hendershot. “EKRA exceptions, however, are more narrowly defined. Under EKRA, payments to employees that vary based on tests performed or payments received, for example, are prohibited.”\nCOVID-19 testing labs should also review financial arrangements with referral sources and related to patient copay and coinsurance waivers. Similarly, physicians or physician practices referring patients for testing should review their financial arrangements with medical labs since the law applies to parties on both sides of the prohibited arrangement (both the solicitor and the receiver of prohibited referral or inducement fees).\nLaboratories are not immune from federal prosecution even if testing services are not being reimbursed through federal health care programs, or if they are even being reimbursed at all.\nBecause the government has directed substantial funds to assist in testing, especially for clinical laboratories testing for COVID-19, DOJ will be more involved in ensuring that fraud is not taking place. Keeping a close eye on current protocol means labs can quickly identify whether they are participating in any noncompliant matters, and work to remediate their practices to ensure compliance.\nNeed assistance with ensuring your COVID-19 testing lab is EKRA compliant? Call Hendershot Cowart P.C. today at (713) 909-7323 to discuss how our Houston health law attorneys can help you. Categories:", "pred_label": "__label__POS", "pred_score_pos": 0.7042858600616455}
{"content": "All News\nAn ORNL-led team's observation of certain crystalline ice phases challenges accepted theories about super-cooled water and non-crystalline ice. Their findings, reported in the journal\nNature, will also lead to better understanding of ice and its various phases found on other planets, moons and elsewhere in space.\nOAK RIDGE, Tenn., March 20, 2019—Direct observations of the structure and catalytic mechanism of a prototypical kinase enzyme—protein kinase A or PKA—will provide researchers and drug developers with significantly enhanced abilities to understand and treat fatal diseases and neurological disorders such as cancer, diabetes, and cystic fibrosis.\nAs the rise of antibiotic-resistant bacteria known as superbugs threatens public health, Oak Ridge National Laboratory’s Shuo Qian and Veerendra Sharma from the Bhaba Atomic Research Centre in India are using neutron scattering to study how an antibacterial peptide interacts with and fights harmful bacteria.", "pred_label": "__label__POS", "pred_score_pos": 0.7044256925582886}
{"content": "Melanoma diagnosis can be done by a physical examination. During the exam, your dermatologist will examine your skin looking for lesions that can indicate melanoma. Your dermatologist may suspect melanoma based on the appearance of the lesion. In some cases, he can complete the exam by a dermatoscopic analysis, analysis of the skin lesion with a specific microscope.\nHowever, to confirm the diagnosis, a biopsy is necessary. Your physician will remove samples from the suspect lesion (biopsy) for laboratory analysis. This histological examination is essential to accurately confirm that you have melanoma. Besides the confirmation of the disease, biopsy can also you’re your doctor measure the exact deepness or thickness of the lesion in your skin.", "pred_label": "__label__POS", "pred_score_pos": 0.9893792271614075}
{"content": "Civil Rights\nBlock on Trump's Asylum Ban Upheld by Supreme Court\nIf a prospective tenant asks, \"Do you accept Section 8?\" how do you respond? Can you say no, or must you always say yes?\nSome landlords like having Section 8 tenants because it's a guaranteed source of on-time rental income. However, others are wary of having to deal with Section 8 bureaucracy and would like to avoid it altogether.\nDo landlords have a choice, or do they have to accept a Section 8 tenant?\nWhat Is Section 8?\nSection 8 of the Housing Act of 1937 created the Housing Choice Voucher Program. The program, more commonly known as Section 8, provides rent assistance to low income individuals.\nSection 8 allows participants to pay up to 30 percent of their adjusted income for rent. Section 8 vouchers cover the rest of the rent amount.\nWhen a Section 8 participant picks a unit to rent, Section 8 housing authority will inspect the rental unit for building and safety code compliance. Common requirements include having an alternate exit in case of fire, working locks on every door or window, safe electrical wiring, working plumbing, and a sufficient number of fire alarms. The housing authority must approve of the unit and the landlord before a landlord can accept Section 8 vouchers.\nSection 8 Discrimination\nUnder the Housing Act, there is no provision requiring a landlord to accept Section 8 vouchers. However, some state and local Fair Housing laws, such as Chicago's Fair Housing Ordinance, do prohibit discrimination based on source of income.\nIf your city or state prohibits this type of discrimination, you cannot reject all Section 8 applicants outright. You cannot advertise \"No Section 8 Accepted\" or \"Section 8 Do Not Apply.\" However, this does not mean you are required to accept every prospective tenant with a Section 8 voucher.\nYou must consider any prospective Section 8 tenant as you would any other tenant. You cannot make screening harder or charge higher rent. If you have multiple units in your building, you cannot limit Section 8 tenants to certain areas or floors of your building.\nIf you are considering participating in Section 8, consult with an experienced landlord-tenant attorney to learn more about the requirements in your area.\nRelated Resources:", "pred_label": "__label__POS", "pred_score_pos": 0.8386396765708923}
{"content": "Another phase of construction has reached completion on the University of British Columbia’s (UBC) Biological Sciences Centre, now formally known as the Undergraduate Life Sciences Teaching Laboratories.\nThe grand opening was held this week for the building at 6270 University Boulevard — located at the prominent southeast corner of the intersection of University Boulevard and Main Mall within the core of the campus.\nSee also:\nOver the last few years, sections of the aging structure were demolished. The 40-year-old north wing’s 59,000 sq. ft. of floor area was renovated, while 57,600 sq. ft. was renewed space, and 97,600 sq. ft. was an expansion as the result of a brand new four-storey east wing.\nThe complex of new and renovated buildings form a quadrangle, framing the new and expanded inner courtyard. A gateway entrance into the complex and courtyard from Martha Piper Plaza features a fully glazed cantilevered lounge and a sheltered wood soffit beneath the structure.\nExterior facade elements of the building feature a biophilic design inspired by the biosciences program, incorporating frit patterns on glazing modelled on stem cell image and natural details such as the patterns on dragonfly wings.\nAdditionally, new building systems that improve the complex’s energy efficiency could provide the project with a LEED Gold green building certification.\n“Sustainable initiatives informed our design to create a highly functional and aesthetic environment for the Biosciences Complex, inspired by connections to nature and connections with the campus to reinforce the significant role of this facility at UBC,” said Donald Schmitt, principal of Diamond Schmitt Architects, in a statement.\nThis project effectively allows for the consolidation of all undergraduate life and biological sciences at the Vancouver campus into one complex, including botany, zoology, microbiology, immunology, physiological sciences, biochemistry, and molecular biology.\nIt has created modernized physical spaces for faculty and over 2,600 students in UBC‘s life-sciences programs, such as state-of-the-art and spacious teaching laboratories, and modern classrooms and study areas that enhance the potential for collaboration and hands-on learning.\nThe project carried a construction cost of $91.4 million, with $32.5 million provided by the federal government, $11.8 million from the provincial government, and $47.1 million from UBC.\nUBC president and vice chancellor Santa Ono says the new and renovated facilities will allow the university to “attract leading life-sciences researchers and ensure our students are inspired to innovate and discover in exceptional learning facilities.”\nRenovations to the original Biological Sciences Centre’s west and south wings were completed in 2011 at a cost of $61.8 million, bringing the entire cost of the complex’s multi-phase renovation and expansion to about $153 million.", "pred_label": "__label__POS", "pred_score_pos": 0.5039858818054199}
{"content": "There may be occasions where students’ academic, professional, and personal development goals are best served by pursuing independent work for a more customized opportunity to learn and grow.\nMBA students have the chance to pursue an independent study in three ways for academic credit with guidance and approval from faculty and the MBA Program Office:\nCurrent Students: Visit the MBA Project Consulting & Experiential Learning Canvas site in the electives section for detailed guidelines on establishing and executing an Independent Study, including the link to submit an application! Academic Independent Study\nAt times, students may be interested in pursuing a traditional academic course that is not offered at the University of Washington. Under these circumstances, students may secure a syllabus from an existing course at another university, complete the work outlined on the syllabus, and author a paper that critically evaluates the content domain of the course.\nResearch Independent Study\nStudents can explore a related topic of interest to a level of depth that suits their academic or professional objectives, creating a Harvard-style teaching case to illustrate the findings and propositions resulting from the research. The case can be based on a concept or a real organization.\nApplied Independent Study\nStudents may engage a company or organization outside UW to address a real-world challenge or opportunity, applying their skills, experience, and critical thinking to execute the project through an interdisciplinary approach. Alternatively, students may execute design and implementation activities for their own startup company (e.g. business plan, go-to-market strategy, target operating model, etc.), using research, analysis, and critical thinking.", "pred_label": "__label__POS", "pred_score_pos": 0.8754496574401855}
{"content": "Asa Kasher and Amos Yadlin have recently argued for a revised principle of distinction under which states should prioritize the protection of their own soldiers over that of noncombatants in certain combat scenarios. The situations that they envision are those in which a state's army is forced to fight terrorists on terrain which is not under the state's effective control. Kasher dramatizes the argument that the soldiers' safety should be prioritized by setting up a hypothetical conversation between the state and a soldier who asks 'Why should my state prefer an enemy citizen over me?' Kasher challenges his readers to offer the soldier a morally compelling answer. This article responds to Kasher's challenge by presenting a dialogue in which a commander (representing the state) offers the soldier four arguments which together provide a convincing answer. The commander grounds his arguments in differences in the amount of choice exercised by soldiers and civilians, the divergent ways the operation can be expected to impact on them, the different obligations they each have to the state, and the likely consequences of emphasizing the safety of soldiers over civilians. The dialogue provides support for the 'double intention' reading of the principle of distinction championed by Michael Walzer.", "pred_label": "__label__POS", "pred_score_pos": 0.5142691135406494}
{"content": "The global furfural market was valued at US$ 416.97 Mn in 2017 and is anticipated to expand at a CAGR of 5.5% from 2018 to 2026, according to a new report titled ‘\nFurfural Market: Global Industry Analysis, Size, Share, Growth, Trends, and Forecast, 2018–2026’ published by Transparency Market Research (TMR). Rise in demand for furfuryl alcohol is driving the global furfural market. Asia Pacific accounts for major share of the global furfural market, led by the increase in usage of furfural in the manufacture of furfuryl alcohol in the region.\nRequest A Sample – Substitution of Fossil Fuel Resources with Renewable Alternatives\nIncrease in concerns about the adverse effects of fossil resources has led to the need for replacement of these fuels with renewable alternatives. Of late, furfural has gained renewed attention as a potential platform for the production of biofuels and biochemicals. U.S. Department of Energy selected furfural as one of the top 30 platform chemicals that can be derived from biomass. Furfural possesses attractive thermosetting properties such as physical strength and corrosion resistance.\nREQUEST FOR COVID19 IMPACT ANALYSIS –\nFurfural is mainly manufactured from biomass. Furfural is less costly and abundantly available. The yield and production of furfural and its derivatives need to improve significantly for the chemical to compete with petroleum-based products. Companies have developed a new technology to produce furfural. This has led to better yield and lower steam consumption vis-à-vis the traditional process. The technology is anticipated to gain wide acceptance in the market in the near future. This is estimated to lower the cost of furfural in the next few years.\nRise in Demand for Furfuryl Alcohol\nFurfuryl alcohol is a commonly derived chemical from furfural. It accounts for almost 80% of the total consumption of furfural. Furfuryl alcohol is the major ingredient in furan foundry binders. This reactive alcohol plays a vital role in the production of foundry sand binders. It has been extensively used to produce cores and molds for metal casting since more than 40 years.\nRead our Case study at :\nLarge portion of furfuryl alcohol is purchased by foundry binder suppliers. The chemical possesses properties such as low viscosity, high reactivity, and excellent solvent characteristics. This has boosted its usage in other fields.\nFurfuryl alcohol is employed in the production of abrasive wheels and adhesives based on urea–formaldehyde resins due to its wetting-dispersant property. It is also used in the production of tetrahydrofurfuryl alcohol (THFA), which is employed as a solvent in the pharmaceutical industry. Furfuryl alcohol is primarily employed in the production of furan resins employed for foundry sand binders in the metal casting industry.\nCurrently, furfuryl alcohol is used widely in binders for traditional furan no-bake systems. In smaller quantities, it is employed in furan hot-box, warm-box, and gas-hardened processes. In its key application, i.e. the foundry sector, furfuryl alcohol competes primarily with phenol, the feedstock for phenolic resins. Thus, increase in demand for furfuryl alcohol in foundry applications is boosting the furfural market.\nInefficient Production Leading to Low Yield and High Product Price\nCurrently, furfural is commercially produced by any of the following major manufacturing processes: Quaker batch process, Chinese batch process, and Rosenlew continuous process. Modern commercial production processes are inefficient (25–35 t steam t−1 furfural) and also give low yield (<50 mol% of theoretical). The cost of running plants is high, as the yield from production processes is less than 50%. This results in high product price. The price of furfural needs to be low for it to achieve higher penetration in various end-user industries.\nProduction processes generate significant quantities of wastewater. This wastewater, which is contaminated with acetic acid and other organic compounds, is expensive to treat. Several China-based furfural plants are compelled to either treat their effluents or cease production.\nAsia Pacific Dominates Global Furfural Market\nIn terms of demand, Asia Pacific is expected to hold dominant share of the furfural market during the forecast period. The furfural market in the region is anticipated to expand at a faster pace than that in other regions during the forecast period owing to the rise in consumption of furfural in foundry and chemical industries in the region. The furfural market in Middle East & Africa is anticipated to expand due to the rise in demand for furfural in the metal casting industry in the region.\nLatin America, especially Brazil, is projected to be an emerging region of the global furfural market during the forecast period. The market in Europe and North America is estimated to expand at a substantial pace during the forecast period due to the presence of well-established fertilizer and chemical manufacturing industries in these regions.\nHigh Degree of Competition among Established Players\nKey players profiled in the report on the global furfural market include Pennakem, LLC, Central Romana Corporation, Silvateam S.P.A., Lenzing Group, Behran Oil Co., ILLOVO SUGAR (PTY) LTD, Aurus Specialty Company, Henan Huilong Chemical Co., Ltd., Shandong Crownchem Industries Co., Ltd., and Hebei Furan International Co., Ltd.", "pred_label": "__label__POS", "pred_score_pos": 0.874885082244873}
{"content": "Abstract\nPURPOSE: To report the response of acute Behcet retinitis to high-dose corticosteroids. METHOD: Case report. A 58-year-old man with Behcet disease and severe bilateral glaucoma experienced a sudden decrease of visual acuity to counting fingers in his (better-seeing) left eye. Examination disclosed hypopyon uveitis and an infiltrative retinitis threatening the fovea. He received intravenous methylprednisolone hemisuccinate, 1 gram per hour on each of 3 successive days, followed by oral prednisone and cyclosporine. RESULTS: The retinal infiltrate disappeared within 24 hours. Visual acuity improved to LE, 20/400 by day 5 and returned to LE, 20/30 after 3 months. A visual field demonstrated a scotoma corresponding to the location of the previous retinitis. CONCLUSION: High-dose intravenous methylprednisolone can reverse severe vision loss in acute Behcet retinitis.\nASJC Scopus subject areas Ophthalmology", "pred_label": "__label__POS", "pred_score_pos": 0.6131744384765625}
{"content": "Last week, the MA House of Representatives released its Fiscal Year 2021 budget proposal. We’re pleased to share that it dramatically increases our Green Budget Coalition’s priority line-items. Areas of significant growth include the Department of Conservation and Recreation, Department of Environmental Protection, and Natural Heritage and Endangered Species Program. These allocations would allow our state agencies to better safeguard our natural resources, protect public health, and work toward our essential climate targets.\nThe past several months have highlighted how vital our outdoor parks and open space are to our community and people. We are grateful to see the House investing in these critical resources.\nThank Your State Representative for funding the environment.", "pred_label": "__label__POS", "pred_score_pos": 0.588585376739502}
{"content": "A group of Canadian citizens have formed the lobby group \"Vegan Option Canada\"\\u00a0to help make plant-based food options mandatory in the public sector. The group, which\\u00a0describes itself as a\\u00a0\"collective of committed citizens sharing a common dream and working together to make this dream a reality,\"\\u00a0is inspired by legislation passed in Portugal last year. After persistent efforts by the\\u00a0Portuguese\\u00a0Vegetarian Association, vegan options became mandatory in public canteens across the country. Similarly, Vegan Option Canada seeks to amend Canadian law to ensure that vegan meal options are available in all public institutions including schools, universities, hospitals, and care centers for the elderly. \"People\\u2019s dietary choices often are not merely preferences and can reflect deeply held ethical beliefs,\" notes the group, adding that in the absence of vegan options, a citizen's \"personal integrity and human rights are violated.\" It continues, \"The fact that a vegan person is forced to eat animal products can be at best, psychologically traumatic, at worst, harmful to...\\u00a0health.\" Already, the group is engaging public support. A formal paper petition sponsored by Marjolaine Boutin-Sweet MP\\u00a0is circulating around vegan-friendly eateries and events across the nation. The group is aiming toto gain 85,000 signatures before January, when the petition will be presented to the federal government. A less formal online petition\\u00a0also boasts over 18,000 signatures. This petition, which the lobby group will use as a\\u00a0\"bonus reference,\"\\u00a0also encourages non-vegans to sign\\u00a0because everyone benefits from a more diverse menu and the possibility of choosing healthier meals. In the future, Vegan Option Canada also plans to present parallel petitions at the provincial level to address institutions under the provincial jurisdiction. A VEGAN-FRIENDLY NATION Veganism was a top searched trend in 2017 according to Google Canada, and a study conducted by Mintel earlier this year showed that more than\\u00a0half\\u00a0of Canadians are opting for vegan alternatives over traditional meat. This followed a\\u00a0Canadian Meat Council-funded study which revealed that the nation is consuming less meat than recommended by Canada\\u2019s Food Guide. Similarly, according to data obtained by Statistics Canada this summer, Canadians are drinking significantly less milk than they once did. Even the government is taking notice,\\u00a0investing $150 million\\u00a0into farms focusing on vegan protein. Become a\\u00a0CLUBKINDLY\\u00a0member today!", "pred_label": "__label__POS", "pred_score_pos": 0.9455705285072327}
{"content": "Hydrocodone/Vicodin Defending Against Prescription Drug Charges\nFlorida has cracked down hard on the possession or sale of prescription drugs without a valid prescription. The state’s desire to cut down on illegal prescription drug use and sales has led to outrageous penalties. For instance, individuals accused of possessing a few pills without a valid prescription can face a mandatory minimum of three years in prison. While oxycodone (OxyContin) charges frequently make the news, the penalties are equally severe for the illegal possession or sale of hydrocodone. Hydrocodone is the primary ingredient in Vicodin and other medications that alleviate pain.\nIf you have been charged with possessing or trafficking in hydrocodone, it is critical to contact an experienced criminal defense lawyer immediately. O’Brien Hatfield Reese, PA, is based in Tampa and defends people throughout Florida against all prescription drug-related charges.\nHydrocodone Offense Lawyers Who Will Be Devoted To Protecting Your Rights\nUnder Florida law, possessing between 4 and 14 grams of hydrocodone without a prescription will bring a\nmandatory minimum prison term of three years. While this is bad enough, penalties for possessing increased amounts of hydrocodone are even worse. Possession of between 14 and 28 grams of hydrocodone will lead to 15 years, and possession of 28 grams or more of hydrocodone brings on a mandatory minimum sentence of 25 years.\nTo make matters worse, these charges are based on the total weight of the pill, not the total weight of the controlled substance. For instance, Vicodin pills are a combination of hydrocodone and acetaminophen, the substance used to make Tylenol. If you are found with, for instance, 5 grams of Vicodin pills without a prescription, the charge will be based on the total weight of the pills, not the total weight of the hydrocodone inside the pills.\nWe will take decisive action aimed at achieving the best possible result in your case. Our skilled, strategic approach has helped many clients avoid the worst penalties associated with drug charges.\nDo You Need A Tampa Hydrocodone Possession Lawyer? Se habla español.", "pred_label": "__label__POS", "pred_score_pos": 0.9555124044418335}
{"content": "Productivity Growth and Disinflation in Chile\nThis paper analyzes the role productivity growth had on disinflation in Chile during the 1990s. It argues that productivity growth was key in avoiding the output costs of stabilization in a highly indexed economy. Disinflation from the early 1990s through 1998 was costless. Among the many external and domestic factors that contributed to good macroeconomic performance, which combined simultaneously very high rates of growth and declining inflation, productivity stands high. The simulations presented in this paper illustrate this point.", "pred_label": "__label__POS", "pred_score_pos": 0.8462679386138916}
{"content": "Intracellular adhesion molecule 1 plays a key role in acquired immunity to salmonellosis. Clare S., Goldin R., Hale C., Aspinall R., Simmons C., Mastroeni P., Dougan G.\nThis study investigated the role of intracellular adhesion molecule 1 (ICAM-1) during Salmonella enterica serovar Typhimurium infection of mice. We show that ICAM-1 is expressed in and around granulomas on day 4 of infection in wild-type mice. However, when naive ICAM-1(-/-) mice were challenged with a sublethal dose of serovar Typhimurium, there were no detectable differences in systemic bacterial burden over the first 9 days of infection compared to wild-type control mice. When mice were immunized with the S. enterica serovar Typhimurium vaccine strain SL2361 and then challenged with the virulent S. enterica serovar Typhimurium strain C5, 100% of the ICAM-1(-/-) mice succumbed to infection, compared to 30% of wild-type mice. T-cell responses, as measured by activation via interleukin-2 production, as well as antibody responses were comparable in the ICAM-1(-/-) and wild-type mice. Following challenge, counts in organs were significantly higher in the ICAM-1(-/-) mice, and histological examination of organs showed pathological differences. Strain SL3261-immunized wild-type mice had cellular infiltrate and normal granuloma formation in the liver and spleen on days 5 and 10 after challenge with strain C5. ICAM-1(-/-) mice had a similar infiltrate on day 5, whereas on day 10 the infiltrate was more widespread and there were fewer macrophages associated with the granulomas. High circulating levels of tumor necrosis factor alpha and gamma interferon, as well as a high burden of strain C5 in the blood, accompanied the differences in histopathology. In this study we show that ICAM-1 plays a critical role during rechallenge of immunized mice with virulent S. enterica serovar Typhimurium.", "pred_label": "__label__POS", "pred_score_pos": 0.9249870181083679}
{"content": "Dangerous winter weather conditions, such as snow, sleet and ice, account for nearly 500,000 car accidents in the U.S. each year.\nFollowing the winter storm that blanketed the east coast recently, many of Pennsylvania’s roadways were covered with thick snow and layers of ice, making it virtually impossible for motorists to drive safely.\nHowever, according to a recent report from the American Automobile Association (AAA), winter weather-related car accidents are less likely to be fatal than accidents that occur during any other season.\nThe New AAA Winter Weather Driving Report\nAAA researchers analyzed data pertaining to weather-related car crashes across the U.S. The results of the study were surprising, as the number of injuries and fatalities from wintertime accidents were significantly lower than those associated with rain or fog-related accidents.\nThe AAA winter weather driving report included the following statistics from 2015:\nRainy and foggy weather caused 539,909 car crashes, 214,641 injuries and 2,613 deaths Snowy weather caused 189,416 car accidents, 51,267 injuries and 523 fatalities Sleet was responsible for 36,491 crashes, 11, 644 injuries and 143 traffic deaths\nOverall, accidents that occurred on snowy or icy roads resulted in 31 percent fewer injuries and 47 percent fewer fatalities than accidents that occurred during rainy, foggy, or even favorable weather conditions.\nWhile this particular study did not analyze data regarding the impact wintry weather has on the overall risk of being in a car crash, other studies have found that car accident rates increase in the wintertime, yet the increase is seen in minor crashes and fender-benders that are unlikely to result in severe injury or death.\nDespite the surprising results of AAA’s latest winter driving study, the car accident attorneys at Schmidt Kramer encourage everyone to stay safe while driving on icy or snow-covered roads.\nDuring adverse winter weather conditions, always remember to decrease your speed, maintain a safe distance between your vehicle and others, and be sure your vehicle’s brakes are in good working order before driving.\nIf you or someone you love has been injured in a wintertime car accident, contact Schmidt Kramer today for a free evaluation of your case. We have the knowledge and experience necessary to get you the justice and compensation you deserve.", "pred_label": "__label__POS", "pred_score_pos": 0.5329538583755493}
{"content": "Hope and anguish in a Mexican refugee shelter\ncamsmanalo\nThis month, a caravan of nearly 1,000 Central American asylum seekers crossed Mexico’s southern border with Guatemala. They followed in the footsteps of more than 7,000 asylum seekers who passed through earlier in October.\nThe Northern Triangle Region of El Salvador, Guatemala and Honduras continues to experience endemic poverty, extremely high homicide rates and widespread gang activity. These dire circumstances drive migration flows to the north.\nThe United States, until recently, was the northern destination of choice for Central American asylum-seekers. It was a “promised land” where they would find personal security and economic prosperity.\nIn contrast with those in earlier caravans, these newcomers to Mexico are unlikely to embark on the futile 4,000-kilometre journey north to the United States. Mobility to the U.S. is becoming increasingly more dangerous and the U.S.-Mexico border is more difficult to cross at both official and unofficial ports of entry.\nPresident Andrés Manuel López Obrador directed officials at the Mexico-Guatemala border to distribute humanitarian visas to the newest caravan. The visas will allow the Central Americans to live and work in Mexican territory for one year while they navigate the country’s refugee determination process.\nCentral American asylum-seekers are now stranded in Mexico. The journey north has left them in a state of limbo, keeping them tacked down in a location where they did not intend to stay permanently.\nMexico attempts to fulfil obligation to refugees\nThe Cartagena Declaration grants protection for people whose lives are threatened by generalized violence who would not be considered refugees under the 1951 UN Refugee Convention.\nIn this respect, Mexico is attempting to fulfil its international obligation to refugees. However, its refugee-protection system is massively under-resourced and unprepared to handle so many asylum cases.\nThe art of the wait for asylum\nAsylum-seekers who hold humanitarian visas often reside in temporary migrant shelters called\nalbergues. Mexico City is home to several albergues that divide guests by age and gender.\nOver the past two years, I have conducted research at one of these shelters, Albergue Tochán in southwestern Mexico City. Tochán (\nnuestra casa, our home in Náhuatl) houses men who have experienced violence in their country of origin or along their journey through Mexican territory.\nTochán responds to the basic needs of the men, including the provision of beds, clothing, meals and toiletries. The tall windowless structure with irregular architecture and steep stairways resembles a clean, warm, welcoming, albeit very cramped home. However, it runs over capacity with far fewer beds than guests.\nWhile at the\nalbergue, the men are free to come and go. They use computers equipped with internet, watch television at specified hours and they adhere to a strict schedule of household chores.\nI interviewed 15 of these men over many hours while accompanying them in daily activities, and visiting with my undergraduate students.\nAs a researcher, I can’t help the thousands of Central Americans who are stranded in Mexico. But, I can help tell their stories. I believe stories can bring some humanity to a population that has been vilified and rendered nameless by recent political discourse.\nThey want to be remembered\nRefugee determination procedures create many uncertainties and anxieties. Asylum-seekers often find themselves in situations of indefinite and unpredictable waiting.\nThe men at Tochán spoke about their current reality and described their daily activities, frustrations and coping mechanisms. They narrated their hopes and aspirations for the future, and they detailed the abuses they endured in the past.\nThe men were keen to talk — they want their stories to be documented. Many asked that they be identified in publications so that they could leave a piece of themselves behind in case they did not survive deportation back to Central America.\nThe men spoke about their sense of exclusion in a new territory. They worried that their asylum claims would be rejected, resulting in official and permanent eviction from Mexico.\nAs days become weeks, and weeks turn into months, their notions of time and space need to be continually recalibrated as the wait drags on.\nWaiting defines their identity. Some of the men reported no longer knowing who they are anymore or what they are waiting for. They described feeling “useless,” “not even human,” “impotent,” “powerless,” like a “beggar” and living “half lives.”\nAnxiety, uncertainty and lack of control over one’s life and future are clearly factors inherent to the collective experience of the men at Tochán.\nFinding unity in art\nThe men have been busy.\nMultiple activities guide the men’s days. They attend Sunday morning mass and afternoon soccer matches, and they craft and sell wooden artesanías, masks and paintings.\nThey paint enormous colourful murals that cover virtually every surface of the\nalbergue and throughout the surrounding neighbourhood.\nWith the assistance of local artists, the director of Albergue Tochán has introduced art as therapy and as a source of income. While hesitant at first, the men have gradually found ways to express and distract themselves through art while they navigate daily, weekly and monthly waiting for the legal validation of their refugee status.\nThrough art, asylum-seekers have been provided the opportunity to share and learn from each other.\nWhile painting together, they find a level of comfort and unity as they learn to trust and rely on each other.\nAs their initial dream of reaching the United States deteriorates during the long wait at the\nalbergue, the men learn to embrace a Mexican hope: the possibility of staying in a new location while waiting for an uncertain future.", "pred_label": "__label__POS", "pred_score_pos": 0.536574125289917}
{"content": "The Contra Costa County Board of Supervisors paid tribute on Tuesday, July 19, to the professionals who serve the County as Probation, Pretrial and Parole Supervision Officers, recognizing their often unsung achievements in contributing to public safety, community engagement, and support for victims.\nMost public safety professionals don’t enter the profession for the recognition, appreciation or financial rewards.\n“There is one particular branch of the profession, though, whose role is keeping communities safe, and yet their crews are far too often overlooked,” noted Supervisor Candace Andersen, Chair of the Board of Supervisors. “Those are the dedicated workers in the community supervision profession, who are the linchpin of the Criminal Justice System. They often don’t wear recognizable uniforms or drive marked cars with lights and sirens, yet they play an equally vital role in ensuring everyone’s safety.”\nIn Contra Costa County, the Probation Department supervises adults placed on Probation as well as individuals being released from prison and being placed on Post Release Community Supervision (PRCS). In the juvenile justice system, the Probation Department operates the Juvenile Hall located in Martinez and Orin Allen Rehabilitation Facility located in Byron, supervises juveniles placed on probation, and provides a wide range of in home and support services aimed at keeping at-risk kids out of custody whenever possible.\nThe probation profession has changed dramatically in recent years, utilizing data and evidence-based practices to more creatively and effectively manage increased caseloads. The implementation of public safety realignment in California, which has resulted in a strong Community Corrections Partnership in Contra Costa County, has added additional responsibilities and opportunities for Probation Officers to make a difference with the individuals we supervise.\nInterim Probation Chief Todd Billeci notes that Contra Costa County’s Probation, Pretrial and Parole team members are innovators in the field, providing service and support for offenders while also providing protection and assistance for victims.\n“Too often, the impact of our staff on public safety might go unnoticed,” Billeci said. “We appreciate the Board of Supervisors taking time to recognize this week as ‘Probation, Pretrial and Parole Supervision Officer’s Week’ and acknowledging the vital role our officers play. Our success comes when we give juveniles and adults the education, job training and life skills they need to enable them to become more industrious citizens in our community.”\nContra Costa County’s Probation Department has been honored for its innovative approaches and high degree of success. Nationally, the week of July 17 – 23, 2016, serves as the official week to recognize the professional achievements of the probation, pretrial and parole supervisors.", "pred_label": "__label__POS", "pred_score_pos": 0.861606240272522}
{"content": "Question:\nWhy wouldn't a contribution designated to a missionary be recorded as a Liability instead of an Equity Fund account as you suggest? Then when the money is sent to that missionary the entry would simply reduce the Liability account.\nAnswer:\nGenerally Accepted Accounting Principles (GAAP) states that donor designated gifts, including missions funds, are considered donor restricted funds. As restricted funds it is best practice to record designated gifts as equity accounts, which falls under GAAP standards. This is true regardless of whether the restriction is temporary or permanent. Temporarily restricted gifts are gifts given by the donor for a specific purpose or program or for use at a certain time. In a church, common temporarily restricted funds might include a missions fund, benevolence fund, building fund, and others. Permanently restricted contributions are gifts given by the donor to be permanently maintained, but the church may use any income that comes from the gift. For example, a member gives a substantial amount of cash hoping to maintain a benefit in perpetuity for missions' families. The donor mandates that the funds be invested and only earnings be used by the church to provide college scholarships to missionary children.\nWhile it is not the best practice, if the congregation is comfortable viewing missionary collections and disbursements as debts (liabilities) the missions funds can be recorded as liabilities as long as no external party insists on a financial statement presentation in accordance with GAAP.\nFor more information on recording designated gifts, see...", "pred_label": "__label__POS", "pred_score_pos": 0.7590193748474121}
{"content": "Kujala MV, Kujala J, Carlson S, et al.\nWe read conspecifics’ social cues effortlessly, but little is known about our abilities to understand social gestures of other species. To investigate the neural underpinnings of such skills, we used functional magnetic resonance imaging to study the brain activity of experts and non-experts of dog behavior while they observed humans or dogs either interacting with, or facing away from a conspecific. The posterior superior temporal sulcus (pSTS) of both subject groups dissociated humans facing toward each other from humans facing away, and in dog experts, a distinction also occurred for dogs facing toward vs. away in a bilateral area extending from the pSTS to the inferior temporo-occipital cortex: the dissociation of dog behavior was significantly stronger in expert than control group. Furthermore, the control group had stronger pSTS responses to humans than dogs facing toward a conspecific, whereas in dog experts, the responses were of similar magnitude. These findings suggest that dog experts’ brains distinguish socially relevant body postures similarly in dogs and humans.", "pred_label": "__label__POS", "pred_score_pos": 0.6593819260597229}
{"content": "Abstract\nNucleoside N-ribohydrolases from protozoan parasites are targets for inhibitor design in these purine-auxotrophic organisms. Purine-specific and purine/pyrimidine-nonspecific nucleoside hydrolases have been reported. Iminoribitols that are 1-substituted with meta- and para-derivatized phenyl groups [(1S)-substituted 1,4-dideoxy-l,4-imino-D-ribitols] are powerful inhibitors for the nonspecific nucleoside N-ribohydrolases, but are weak inhibitiors for purine-specific isozymes [Parkin, D. W., Limberg, G., Tyler, P. C., Furneaux, R. H., Chen, X.-Y., and Schramm, V. L. (1997) Biochemisty 36, 3528-3534]. Binding of these inhibitors to nonspecific nucleoside hydrolase occurs primarily via interaction with the iminoribitol, a ribooxocarbenium ion analogue of the transition state. Weaker interactions arise from hydrophobic interactions between the phenyl group and the purine/pyrimidine site. In contrast, the purine-specific enzymes obtain equal catalytic potential from leaving group activation and ribooxocarbenium ion formation. Knowledge of the reaction mechanisms and transition states for these enzymes has guided the design of isozyme-specific transition state analogue inhibitors. New synthetic efforts have produced novel inhibitors that incorporate features of the leaving group hydrogen-bonding sites while retaining the iminoribitol group. These compounds provide the first transition state analogue inhibitors for purine-specific nucleoside hydrolase. The most inhibitory 1-substituted iminoribitol heterocycle is a sub-nanomolar inhibitor for the purine-specific nucleoside hydrolase from Trypanosoma brucei brucei. Novel nanomolar inhibitors are also described for the nonspecific nucleoside hydrolase from Crithidia fasciculata. The compounds reported here are the most powerful iminoribitol inhibitors yet described for the nucleoside hydrolases.\nASJC Scopus subject areas Biochemistry", "pred_label": "__label__POS", "pred_score_pos": 0.8223654627799988}
{"content": "One of these grants has been awarded to Annemarthe van der Veen of our department, head of the Molecular Biology of Innate Immunity group, for her project ‘Inflammation without infection’.\nIf our immune system is no longer able to distinguish between the body's own molecules and microbial molecules such as viruses, this leads to autoinflammatory disorders. \"An inflammatory reaction then takes place without there being an infection\", explains Van der Veen, researcher at the Immunology department. \"We are going to investigate the causes of such a sterile inflammation\".", "pred_label": "__label__POS", "pred_score_pos": 0.6629889011383057}
{"content": "\"The role of the pharmaceutical industry is to deliver therapeutic innovations and bring them to real-life medical practices. Therefore, a critical component of pharma players’ operating model is using customer engagement to create a lasting bond, infused with value and trust, with the healthcare ecosystem. It is this bond which enables to transform these innovations into care practices and bring efficient and safe treatment options to patients to improve their lives\nWith this paper we aim to help decision makers within pharma companies reach this goal and excel in its execution while adapting it to today’s digitalized world, made even more online-driven by the covid-19 pandemic.\nThis paper was conceived as a pragmatic recipe based on the questions that pharmaceutical companies from all over the world are facing daily. It is not meant to reinvent theoretical bases or to be only used as inspiration, but rather to provide in the same document: basics on this matter, practical tips, a path for creation and deployment, elements of inspiration from other sectors, insights related to the digital transformation of customer engagement, and food for thought for the post covid-19 crisis. These elements form a methodological canvas, useful for reshaping and implementing new customer engagement models for 2020 and beyond.\"", "pred_label": "__label__POS", "pred_score_pos": 0.9881889224052429}
{"content": "Southern Tick-Associated Rash Illness (STARI) Southern tick-associated rash illness (STARI) is a Lyme disease-like illness that produces an expanding circular skin rash (erythema migrans) at the site of attachment from the lone star tick within approximately seven days. Lone star ticks are commonly found in Oklahoma, and are known to aggressively bite humans. It has been described in patients in the southeastern and south-central states, including Oklahoma. This illness is indistinguishable from the early stages of Lyme disease. The rash may be accompanied by a mild illness characterized by fever, generalized fatigue, headache, muscle and joint pain. STARI is not listed specifically as a reportable disease/condition, but it is uncommon and should be reported to the Acute Disease Service within one business day.\nAn etiologic agent has not yet been definitively identified; therefore there are no commercial laboratory tests to test patients for this illness. It is still unclear as to whether antibiotic treatment is necessary or beneficial for patients diagnosed with STARI. Nevertheless, physicians often treat patients with oral antibiotics as the illness so closely resembles Lyme disease. Contact your physician if you think you might have STARI, or any symptoms of illness that develop within two weeks of tick exposure. Prevention measures for STARI are similar to other tickborne diseases: avoid tick-infested areas, frequently check to identify and remove ticks properly, and use tick repellant when indicated.\nExternal STARI Resources: STARI (CDC)", "pred_label": "__label__POS", "pred_score_pos": 0.5177868604660034}
{"content": "Projects per year\nAbstract\nNanotechnology is identified as a key enabling technology due to its potential to contribute to economic growth and societal well-being across industrial sectors. Sustainable nanotechnology requires a scientifically based and proportionate risk governance structure to support innovation, including a robust framework for environmental risk assessment (ERA) that ideally builds on methods established for conventional chemicals to ensure alignment and avoid duplication. Exposure assessment developed as a tiered approach is equally beneficial to nano-specific ERA as for other classes of chemicals. Here we present the developing knowledge, practical considerations and key principles need to support exposure assessment for engineered nanomaterials for regulatory and research applications.", "pred_label": "__label__POS", "pred_score_pos": 0.9999964833259583}
{"content": "Abstract\nWe investigated the role of gathering and selling the edible tubers of wild orchids by children orphaned by AIDS as one of their livelihood strategies, through a household survey administered to 152 households in three villages in the Southern Highlands of Tanzania during 2006 and 2007. Additionally, several household heads were selected as case studies and subjected to an in-depth life-history interview. Overall, most households in the study villages were very poor. We made comparisons within a total sample of 57 households headed by children orphaned by AIDS, 43 adult female-headed AIDS-affected households, and 52 adult male-headed non-AIDS-affected households in terms of food security and wealth outcomes after engaging in orchid tuber-gathering activities. The findings reveal that the majority of the orphan heads of households regarded the gathering and selling of wild orchid tubers as the best option for satisfying their basic needs. This category of households gathered more orchid tubers than the male-headed non-AIDS-affected households but not more than the female-headed AIDS-affected households. Children in these households spent more time on tuber-gathering activities than did members of the other households but had fewer household assets. Almost all the orphan-headed households depended on the cash obtained from selling orchid tubers to purchase food throughout the year. However, we surmise that gathering and selling wild orchid tubers fails to pull these children out of poverty and functions merely as a survival strategy.\nKeywords coping strategies south-africa diversification products trade aids", "pred_label": "__label__POS", "pred_score_pos": 0.6036770939826965}
{"content": "When drafted properly, employment contracts give employees and employers clear guidance concerning both parties’ rights and responsibilities to one another during their working relationship. If executed at the start of employment, these agreements could even reduce the likelihood of future disputes, sparing both parties from having to expend time and energy on costly litigation.\nA Georgia employment contracts lawyer could represent you during negotiations and advise you on the types of provisions that should be included in your agreement. Our team could even draft an employment agreement on your behalf. Should a contract dispute arise, a seasoned employment law attorney could also provide you with zealous legal representation during arbitration or court proceedings.\nIn Georgia, employers do not have to enter into contracts with their workers. However, employers and employees may mutually decide to execute an agreement. Employment contracts have many benefits, such as protection from wrongful termination and protection of trade secrets.\nIf you are an employee, an employment contract that contains termination provisions could provide you with increased protection from being fired or discharged at-will by your employer. Work agreements may also outline your compensation schedule, bonus structure, and benefits packages, providing you with proof that you are entitled to specific compensation if a dispute arises.\nAs an employer, you might find that entering into employment contracts with key personnel could protect your business from outside competition. For example, you could include a non-compete clause in your agreement that restricts employees’ from working for competing companies or establishing competing companies after leaving their job. Similarly, if you want to protect trade secrets or proprietary information from your competition, you could insert a non-disclosure provision in the employment contract.\nThere are many advantages to hiring legal counsel to execute an employment contract. An attorney could evaluate your agreement to determine if your rights are being protected.\nIt is crucial that the terms of your employment agreement are clear and specific. Certain provisions that you may consider including in your contract include:\nAn agreement might also detail both parties’ ability to arbitrate or litigate contract disputes, where they may file claims, and the state laws governing such conflicts. A dedicated employment contracts attorney could help you draft an agreement that contains all of these critical provisions.\nEven if terms of your agreement are clearly outlined, disputes may still arise. In these cases, an attorney could help you file a claim and advocate for you during legal proceedings.\nBefore executing an employer-employee agreement, you should speak with an attorney at Sparks Law. A Georgia employment contracts attorney could explain the advantages of executing an agreement advise you on the types of contract provisions to include in the document. Reach out to our office to find out what we could do for you.", "pred_label": "__label__POS", "pred_score_pos": 0.6079465746879578}
{"content": "The widespread physical activity guidelines for adults recommendsat\nleast 150 minutes per week of moderate-intensity exercise or 75minutes of vigorous intensity exercise. The benefits of completing thisamount of weekly exercise are widely recognised. Despite this, the majority ofadults fall short of the recommended physical activity guidelines with lack oftime cited as the primary barrier to achieving weekly exercise goals. As aresult, the use of high intensity interval training (HIIT) has beeninvestigated as a more time-efficient strategy to improving health. What is HIIT?\nHigh intensity interval training uses short bursts of high intensity activity followed by a recovery period at a lower intensity. This ‘high intensity’ period may sound daunting for those newer to cardiovascular training. However, an individualised approach based on guidance from medical specialists and heart rate data ensures a safe and effective method of training. It must be assumed that any individual with a clinically relevant cardiovascular disease risk factor or diagnosed cardiovascular disease requires both a medical examination and a physician-supervised maximal exercise test prior to participation in HIIT (ACSM, 2010).\nWhat are the benefits of HIIT?\nThe benefits of HIIT within the general population have been widely researched and accepted however, a growing body of evidence has investigated the safety, efficacy and enjoyment of a HIIT protocol within a cardiac population.\nModerate intensity continuous training (MICT) has traditionally been a foundation of aerobic-base exercise prescription resulting in short and long-term clinical benefits for individuals with cardiovascular disease. However, emerging research suggests using HITT alongside or as an alternative to MICT can result in similar or greater improvements in peak VO2 (the threshold of your body’s ability to transport and use oxygen during physical activity).\nSimilarly, a recent study by Keech et al (2020)found positive efficacy for reducing cardiovascular risk, high levels ofpatient enjoyment and no cardiovascular-related adverse events associated withthe training. Specifically, researchers found significant reductions in both\nbloodpressure and body fat. Importantly for cardiovascularrisk, the fat loss appeared to disproportionately come from central areasand visceral fat stores within the trunk.\nIn addition, aerobic fitness also improved by an averageof 12% or nearly 1 MET. As a reference, previous research has foundimprovements in cardiovascular fitness by 1 MET equates to a\n∼ 8–17% reduction in all-cause and cardiovascular-related mortality. fatigue tolerance, running performance and bloodglucose profile specific to the interval protocol. How do we monitor HIIT?\nThe physiological and psychological demands of HIIT are greater compared to steady state training. Therefore, sufficient preparation and recovery is incredibly important to the safety and success of the individual. This not only includes a sufficient warm up and cool down but also adequate hydration and nutrition surrounding the HIIT sessions to ensure individuals are fuelling each session as best as possible to achieve optimal results and recovery.\nSimilarly, through the use of heart rate monitors, HIIT sessions can be monitored to ensure individuals are adhering to the target exercise intensity. This not only ensure optimal physiological adaptations but also the safety of the individual.\nSummary\nIn summary, with sufficient medical screening andguidance, high intensity interval training offers individuals withcardiovascular disease an alternative method to improve cardiovascular fitness,increase physical activity and reduce cardiovascular risk. Asa team, we pride ourselves of staying at the forefront of new research to adaptand grow to find the safest, effective and enjoyable approach to help ourathletes\nlive longer, better.", "pred_label": "__label__POS", "pred_score_pos": 0.9882224202156067}
{"content": "A potential sales tax on self-storage has once again been introduced to the legislature in North Carolina, and the national and North Carolina Self Storage Associations have jumped to combat the measure. If passed, Senate Bill 658, 21\nst Century Tax Modernization Plan, would impose a sales tax on self-storage rentals in the state.\nSB 658 was introduced on April 19 and referred to the House Standing Committee on Finance on April 20. Information about the bill can be viewed at www.ncga.state.nc.us/gascripts/BillLookUp/BillLookUp.pl?Session=2011&BillID=S658.\nThe NCSSA hopes to get as many of the states self-storage owners and operators as possible to visit their local representatives and discuss why self-storage should be taxed as real estate, not a service. The association is also aiming to raise $20,000 in 2011 to battle the tax.\nSSA president and CEO Mike Scanlon sent a letter to the bills sponsor, Senator Daniel G. Clodfelter (D-Mecklenburg), reminding him that the self-storage portion of the bill will be passed on to consumers, who may often be from low-income households (single parents, retirees, students, soldiers, small-business owners, etc.). Scanlon wrote it is arbitrary to include only one commercial real estate sector in the bill, and that self-storage already contributes real estate taxes. His letter ultimately urges the removal of self-storage and mini-storage from the tax proposal.\nThe threat of sales tax was previously faced by North Carolina self-storage operators in 2009, when senators contemplated new sources of tax revenue. In October of that year, the NCSSA met Representative William L. Wainwright to discuss the harmful impact of such a tax.", "pred_label": "__label__POS", "pred_score_pos": 0.5630017518997192}
{"content": "After nearly a decade of austerity our schools are at breaking point. Over 600,000 children are being taught by unqualified teachers. Nearly half a million children are crammed into super-sized classes.\nThat’s why this week Labour announced our plan to improve educational standards for all children. We will:\n📚 Cap all class sizes at 30 by recruiting nearly 20,000 more teachers;\n📚 Guarantee that every child is taught by a qualified teacher, ensuring around 25,000 currently unqualified staff are fully trained during Labour’s first term in office;\n📚 Ensure teachers will have more time for lesson planning and professional development;\n📚 Invest in ensuring that all school buildings are safe, with a new fund of over £7bn to tackle the backlog of vital but overdue repairs and install safety measures such as sprinklers;\n📚 Close the gap in funding for pupils with Special Educational Needs and Disabilities, with extra funding to reverse deficits in the High Needs Budget;\n📚 Fully reverse cuts to the Pupil Premium, and increase spending on it above inflation to support the most disadvantaged pupils.", "pred_label": "__label__POS", "pred_score_pos": 0.7984863519668579}
{"content": "Controlled burning is a common restoration technique in midwestern forests. This project examines its effects on soils, which are largely unknown, but can have significant impacts on tree growth and young tree establishment.\nThe number of species that can tolerate poor-quality of roadside soils is limited. Can we increase the diversity of trees that can thrive in this harsh environment and increase the ecosystem services they provide by matching soil amendments with tree traits?", "pred_label": "__label__POS", "pred_score_pos": 0.6873785257339478}
{"content": "Early fundamental guidelines on using sodium hypochlorite in swimming pools28 October 2020\nIn the late 1970s, Andy Elphick wrote a technical paper on\nThe Treatment of Swimming Pool Water With Sodium Hypochlorite, which was distributed by Wallace and Tiernan to UK pools.\nThe paper was written as a consequence of the phasing out of gaseous chlorine and the change to other forms of chlorine.\nIt provided guidance on how to convert a pool from chlorine gas to sodium hypochlorite, the differences involved and the consequences.\nThis was a change that many managers still regret and upon which Andy cautioned due consideration to ensure success.\nYou can download Andy’s paper by clicking here.", "pred_label": "__label__POS", "pred_score_pos": 0.5982354879379272}
{"content": "National, provincial, and local economists met at the Canada Mortgage and Housing Corporation Housing Outlook Conference November 4th here in Vancouver. The consensus from the conference hosted by Canada’s housing Agency: Housing in the Lower Mainland will remain strong well into 2016.\nEconomists at the conference cited three key reasons for their conclusions:\n1) the overall economy is expected to continue to improve, attracting immigrants and new residents to the area\n2) Interest and mortgage rates are expected to remain at record lows until at least the end of 2015 3) Baby boomers will continue to downsize, ensuring demand for townhouses and condos\nIn the final analysis, then, while the market has been hot, it does not show any sign of slowing down in the near future.", "pred_label": "__label__POS", "pred_score_pos": 0.9672251343727112}
{"content": "The United Pet Group announced that it is issuing a voluntary recall targeting rawhide dog chews from several brands including American Beefhide and Healthy Hide, among others. These products may potentially be contaminated with a chemical compound.\nUnited Pet Group Voluntary Recalls Multiple Brands of Rawhide Chew Products for Dogs Due to Possible Chemical… https://t.co/cEKDkD4vKe\n— U.S. FDA (@FDArecalls) June 10, 2017\nThe Rawhide Dog Chews Recall Targets Five Brands\nUnited Pet Group’s decision to issue this voluntary recall was announced in a press release on the U.S. Food and Drug Administration Safety page. In it, the authority offered a complete list of the recalled goods.\nAccording to the statement, United Pet Group initiated the recall after detecting that several of its rawhide chew facilities were using a quaternary ammonium compound mixture. This was utilized in facilities situated in Colombia, Mexico, and by one of the Brazil suppliers.\nThe ammonium compound is an antimicrobial chemical, approved for utilization as a food processing equipment cleaner. However, these facilities used it as a processing aid when manufacturing the rawhide dog chews, which is not approved in the United States.\nSo the United Pet Groups decided to recall multiple packages with such products from several brands. These were distributed across the U.S. both to local retail outlets and also online. The recall includes rawhide chews from Digest-eeze, American Beefhide, Healthy Hide Good-n-fit, Healthy Hide Good-n-Fun, and Healthy Hide.\nThis recall is limited to just products containing rawhide. It also only includes products whose codes, listed on the back, start with A, AI, AB, AO, AH, and AV. Their expiration date must also be in between 06/01/2019 to 05/31/2020, and this includes packages of all weights and/or sizes.\nOne of the main complaints with these rawhide dog chew products was their unpleasant odor. Owners also reported that their dogs vomited or had similar such issues.\n“United Pet Group received very limited reports of pet illness based on the volume of possibly affected rawhide chew products manufactured and distributed.”\nExposure to the ammonium compound through direct consumption has symptoms such as a reduced appetite or gastric irritation.\nConsumers that acquired the recalled products are urged to dispose of them or to return them either to the point of purchase or the United Pet Group for a full product refund.\nImage Source: Wikimedia", "pred_label": "__label__POS", "pred_score_pos": 0.8126124143600464}
{"content": "Children are an important stakeholder group for sustainable development, as they represent the interface between current and future generations. A comprehensive assessment of child development (CD) in the context of sustainable development is still missing. In this paper, as a first step, a literature review is conducted to identify relevant aspects and gaps related to the assessment of CD. The main issues of CD are categorized into seven themes: health, education, safety, economic status, relationships, participation, and newly proposed environmental aspects. The corresponding subthemes and criteria are classified accordingly (e.g., nutrition, child mortality, immunization, etc., are assigned to the theme health). However, gaps in current studies, such as the heterogeneous classification of relevant aspects, regional and societal bias in addressing certain aspects, the limited number of subthemes, and criteria and the missing inclusion of environmental aspects impede the assessment of sustainable child development. To address the existing gaps, a comprehensive framework, the Sustainable Child Development Index (SCDI), is proposed. The SCDI is based on sustainable development as the core value, considers relevant aspects of CD with regard to newly-proposed environmental aspects and includes 26 aspects on an outcome and 37 indicators on a context level to tackle the heterogeneous classifications and interdependencies of relevant aspects. The proposed index intends to strengthen the stakeholder perspective of children in sustainability assessment.", "pred_label": "__label__POS", "pred_score_pos": 0.82027667760849}
{"content": "We recently released a new issue paper exploring the stigma experienced by pregnant and parenting women who used substances during pregnancy. Below is a short summary of this paper.\nIssue\nSubstance use and addiction are highly stigmatized in our society. The impact of stigma on mothers who use substances during pregnancy can have a wide range of negative effects on their health and well-being. Stigma may result in women choosing not to disclose their substance use out of fear of judgement or punishment; it may contribute to service providers using judgemental or punitive approaches to child welfare; it may limit the services and supports available to women who use substances; and it may contribute to a stereotype that depicts a certain “type” of mother of children with FASD, resulting in an unbalanced focus on these individuals and a lack of concern regarding the substance use habits of women who don’t fit this stereotype.\nBackground\nThis paper follows the stigma framework outlined by the Chief Public Health Officer of Canada her 2019 Addressing Stigma report.\nInternalized Stigma and its Impact on Women’s Self-Efficacy: Societal attitudes and media portrayals perpetuate the stigma surrounding substance use and pregnancy, which can lead to women internalizing these negative beliefs. Internalized stigma can lead to increased feelings of guilt and fear and a decrease in self-esteem, confidence, and the ability or willingness to seek support. Interpersonal Stigma and its Impact on Access to Prenatal Care and Substance Use Treatment: Stigma is one of the biggest barriers to pregnant women accessing and receiving care for substance use. Judgemental or abstinence-only responses from health care providers can result in further feelings of shame and fear of judgement, which can discourage women from seeking support. Institutional Stigma and its Impact on Women’s Access to Trauma-Informed and Harm Reduction Oriented Services: Organizational policies that require women to be abstinent from substance use can limit their access to necessary services. Health practitioners often have a lack of training in effective substance use counselling for women, which can perpetuate negative stereotypes and result in misinformed “solutions” being presented. Negative experiences with health practitioners can increase women’s distrust and fear of social services, negatively impacting their health and well-being. Recently, some Canadian provinces have shifted policies to prioritize keeping families together, which can alleviate some of the distrust in the system that many women feel. Population Level Stigma Arising from Public Health Messaging and Media Representations: The media often portrays mothers who drink alcohol during pregnancy as irresponsible, immoral, or villainous, which perpetuates negative stereotypes and misconceptions. Health care providers may only ask individuals from specific subpopulations to disclose their substance use, rather than asking for transparency from all women and girls. The public narrative surrounding alcohol use in pregnancy is heavily stigmatized, and often perpetuates misinformation surrounding “safe” levels of alcohol consumption in pregnancy. Take Home Message: Women who use substances in pregnancy or who have children with FASD experience stigma from the media, health and social service providers, and members of society, that can limit their access to necessary health and social services. FASD-informed, trauma-informed, and harm reduction-oriented health messaging and health education is needed to support women to access those services.\nFor more information, including recommendations, please refer to the full issue paper here.\nAuthors: Kirsten Morrison, Lindsay Wolfson, Kelly Harding, & Nancy Poole Date: February 2020", "pred_label": "__label__POS", "pred_score_pos": 0.9846888184547424}
{"content": "From Venezuela’s Petro to JPMorgan’s stable coin and China’s Digital Currency Electronic Payment (DCEP), the rising adoption of Cryptocurrencies from mainstream players has led to greater interest from both retail investors and professionals from top financial institutions. This guide aims to equip beginners with sufficient knowledge to begin profiting from investing in and trading cryptocurrencies.\nWhat is Cryptocurrency?\nBroadly speaking, cryptocurrencies are a class of digital assets that can serve as a medium of exchange. While there exists much contention on defining cryptocurrencies as currencies due to their questionable ability to serve as a unit of account, means of storing value and effective medium of exchange at the same time, few can argue with the growing prominence of cryptocurrencies led by Bitcoin’s meteoric rise as the best performing asset of the decade.\nThere exists a wide range of cryptocurrencies in today’s market with differing purposes and natures other than the prominent coins such as Bitcoin and Ethereum.\nFor example, government-issued cryptocurrencies such as the recent DCEP issued by the People’s Bank of China serves as a digital replacement with the same value as their fiat currency. There are stable coins such as the USDT and BUSD issued by private companies such as Tether and Binance respectively, which are backed by the US dollar.\nLast but not least, there exists a large pool of cryptocurrencies with smaller market capitalizations than Bitcoin and Ethereum. Such cryptocurrencies are often referred to as Altcoins by the crypto community. To date, Bitcoin remains the most successful cryptocurrency with the largest Market Capitalization of around $160 billion dollars, followed by Ethereum with a Market Capitalization of around $22 Billion Dollars.\nWhy trade Cryptocurrency instead of other assets today?\nWhile the cryptocurrency market remains extremely volatile compared to the stock, commodities and foreign exchange markets, this risk does not go unrewarded to investors. A quick look at Bitcoin’s historical Sharpe ratio (a metric to measure returns per unit of risk) since inception has shown that Bitcoin has outperformed other investments such as stocks, real estate, bonds, and even gold on a risk-adjusted basis over a 4-year holding period. While this is by no means recommending users to invest solely in Bitcoin, it does suggest that there are significant benefits to investing in cryptocurrencies.\nAdditionally, investing in Bitcoin and cryptocurrencies can bring about significant diversification benefits to an investor’s portfolio due to its low correlation with market indices. Bitcoin has an average correlation to major market indices of 0.05, which can greatly reduce a portfolio’s overall volatility and hence its Sharpe ratio.\nIf you still remain unsure about entering the Cryptocurrency trading space, the CryptoHero mobile app has a paper trading function to allow users to experience simulated Cryptocurrency trading.", "pred_label": "__label__POS", "pred_score_pos": 0.998305082321167}
{"content": "UNHCR just published an extensive report on credibility assessment in EU asylum systems. The report also covers the use of Country of Origin Research (COI) for assessing credibility.\nThe report “ Beyond Proof – Credibility Assessment in EU Asylum Systems” was publishd as part of the project Towards Improved Asylum Decision-Making in the EU (also called CREDO project) and aims to contribute to the further harmonization of Member State practices in terms of assessment of credibility. This report seeks to clarify some key concepts, reference key standards, outline factors that have a bearing on the credibility assessment. It also aims to provide some insights into state practices on specific aspects of the credibility assessment. Today there is a strong need for comprehensive and up-to-date guidance on credibility assessment to address the challenges faced by adjudicators in asylum systems.\nUNHCR has therefore embarked on the review of its own guidance with a view to producing updated guidelines on credibility assessment that reflect recent developments in international refugee law and other relevant areas of law. This report thus does not constitute that updated guidance, although its findings will be taken into account in the guidance’s preparation process ».\nRegarding the use of COI, see chapters 4.4.1. (on gathering COI, p. 128-130) and 5.4. (consistency of the applicant’s statements with COI, p. 173-175). The report is available in a 288 pages full version, and as a 72 pages summary. It can be downloaded via Refworld: http://www.refworld.org/cgi-bin/texis/vtx/rwmain?page=search&skip=0&query=beyond+proof&coi=", "pred_label": "__label__POS", "pred_score_pos": 0.9372668266296387}
{"content": "Abstract\nComplex dendrites in general present formidable challenges to understanding neuronal information processing. To circumvent the difficulty, a prevalent viewpoint simplifies the neuronal morphology as a point representing the soma, and the excitatory and inhibitory synaptic currents originated from the dendrites are treated as linearly summed at the soma. Despite its extensive applications, the validity of the synaptic current description remains unclear, and the existing point neuron framework fails to characterize the spatiotemporal aspects of dendritic integration supporting specific computations. Using electrophysiological experiments, realistic neuronal simulations, and theoretical analyses, we demonstrate that the traditional assumption of linear summation of synaptic currents is oversimplified and underestimates the inhibition effect. We then derive a form of synaptic integration current within the point neuron framework to capture dendritic effects. In the derived form, the interaction between each pair of synaptic inputs on the dendrites can be reliably parameterized by a single coefficient, suggesting the inherent low-dimensional structure of dendritic integration. We further generalize the form of synaptic integration current to capture the spatiotemporal interactions among multiple synaptic inputs and show that a point neuron model with the synaptic integration current incorporated possesses the computational ability of a spatial neuron with dendrites, including direction selectivity, coincidence detection, logical operation, and a bilinear dendritic integration rule discovered in experiment. Our work amends the modeling of synaptic inputs and improves the computational power of a modeling neuron within the point neuron framework.\nOriginal language English (US) Pages (from-to) 15244-15252 Number of pages 9 Journal Proceedings of the National Academy of Sciences of the United States of America Volume 116 Issue number 30 DOIs State Published - Jul 23 2019 Keywords Dendritic computation Point neuron model Single-neuron dynamics Synaptic current Synaptic integration ASJC Scopus subject areas General", "pred_label": "__label__POS", "pred_score_pos": 0.5313746929168701}
{"content": "Abstract\nIntegrin\nα6 β4 is a cellular adhesion molecule that binds to laminins in the extracellular matrix and nucleates the formation of hemidesmosomes. During carcinoma progression, integrin α6 β4 is released from hemidesmosomes, where it can then signal to facilitate multiple aspects of tumor progression including sustaining proliferative signaling, tumor invasion and metastasis, evasion of apoptosis, and stimulation of angiogenesis. The integrin achieves these ends by cooperating with growth factor receptors including EGFR, ErbB-2, and c-Met to amplify downstream pathways such as PI3K, AKT, MAPK, and the Rho family small GTPases. Furthermore, it dramatically alters the transcriptome toward a more invasive phenotype by controlling promoter DNA demethylation of invasion and metastasis-associated proteins, such as S100A4 and autotaxin, and upregulates and activates key tumor-promoting transcription factors such as the NFATs and NF- κB. Expression of integrin α6 β4 has been studied in many human malignancies where its overexpression is associated with aggressive behavior and a poor prognosis. This review provides an assessment of integrin α6 β4 expression patterns and their prognostic significance in human malignancies, and describes key signaling functions of integrin α6 β4 that contribute to tumor progression. Document Type\nArticle\nPublication Date\n9-2015\nDigital Object Identifier (DOI)\nhttps://doi.org/10.1038/labinvest.2015.82\nFunding Information\nThis work was supported by National Institutes of Health grants T32 CA160003 (to RLS) and R01 CA109136 (to KLO).\nRepository Citation\nStewart, Rachel L and O'Connor, Kathleen L, \"Clinical Significance of the Integrin α6β4 in Human Malignancies\" (2015).\nPathology and Laboratory Medicine Faculty Publications. 32. https://uknowledge.uky.edu/pathology_facpub/32", "pred_label": "__label__POS", "pred_score_pos": 0.6472254991531372}
{"content": "Polynerve is a new device which will revolutionise the field of nerve repair\nDigital nerve injuries often affect young people of working age, impacting their daily life, causing ongoing cost and resulting in permanent disability despite surgical intervention. In cases where the nerve gap is larger than 5mm an end to end suture repair is not possible and surgeons are forced to use an autologous nerve graft.\nAutologous nerve grafting is problematic due to the need for a second surgical site where the donor nerve is harvested. Donor site morbidity, loss of sensation and pain from neuroma formation can occur at the donor site, often in addition to poor clinical outcomes at the repair site.\nPolynerve has completed phase I clinical trials which had the primary objective of assessing safety of the device. Polynerve aims to replace the need for an autologous nerve graft, removing the risk of complications from the second surgical site with equivalent nerve repair outcomes.\nPolynerve’s competitive advantage lies within the specifically designed surface topography that guides the regenerating nerve across the gap whilst the conduit provides physical protection and support.\nAdditional device geometries can be crafted in addition to tube shapes to make a range of products to suit the specific surgical need.\nFor more information, please contact:\nKatherine Horner\nkatherine.horner@uominnovationfactory.com", "pred_label": "__label__POS", "pred_score_pos": 0.9182136058807373}
{"content": "Distressed debt and special situations: Succeeding in uncertain times\n03 November 2020\nDebtwire is pleased to present “\nDistressed debt and special situations: Succeeding in uncertain times”, published in association with MinterEllison.\nThe ongoing global pandemic has made uncertainty the new normal. While the short-term impacts on global markets and the Australian economy are apparent, the long-term impacts and permanent changes to society and business can only be speculated.\nAgainst this backdrop and without a marker to the finish line, Australian businesses are attempting to steer a course not only for survival but for the growth needed to be a viable long-term concern. But alongside uncertainty comes opportunity – especially for distressed debt and special situation investors.\nThis report explores the opportunities in a distressed market, drawing on Debtwire market intelligence and insight from MinterEllison’s thought leaders.\nKey highlights include: Australian market update:A brief overview from Debtwire’s Asia editorial team on the state of the Australian market, development sin 2020 and the outlook to yearend and early 2021. Sector snapshot:A close look at key distressed industries and trends shaping various sectors that could open opportunities for distress debt and special situations investors. Featured Q&As:MinterEllison experts discuss Australia’s advantages and the key opportunities and challenges for global investors searching for distressed investments. Restructuring and turnaround best practices:MinterEllison’s insights into best practices in managing a successful restructuring or turnaround amid market volatilities and uncertainty.", "pred_label": "__label__POS", "pred_score_pos": 0.8182636499404907}
{"content": "Journalists, Civil Society Organizations, and Public Officials all work on creating a better understanding of Public Budgets and Expenditures. Often, internal processes on liberating those fiscal data could seem black boxes from the outside. We’d like to unpack these work processes to foster better cooperation and understand what role open data can play.", "pred_label": "__label__POS", "pred_score_pos": 0.8507518768310547}
{"content": "It is advisable that you wake up early in the morning, preferably between 5:30 am and 8:30 am in the morning. You could consume your first meal, which is your breakfast, anywhere between 5:30 am and 8:30 am in the morning. Your breakfast could start with 3 tablespoons of rice protein powder from any popular brand. This powder can be consumed by adding it to a solution of 8 ounces of almond milk and another 8 ounces of soy milk.\nThis can be followed by around half a cup of frozen mango or strawberries. You can provide your stomach with its necessary does of healthy and essential fats, by drinking a tablespoon full of coconut oil. Finally, you could wrap up your breakfast with a multi vitamin tablet and a couple of mineral supplements.\nAfter 2 or 3 hours of your first meal, which is your breakfast, you are now ready for the second meal of your day. This meal is basically had at mid-afternoon time and is often called a brunch, because it’s neither breakfast nor lunch, but somewhere mid-way and hence, brunch. You could have 1 cup of dry fruits, comprising of around half a cup of almonds, and another half a cup of raisins. This can be very filling.\nWait it out another 2 or 3 hours, and you are now fully ready for your next major meal of the day, which is your lunch. For lunch you are free to have two entire burgers, with the breads used being whole wheat breads. You could load them with a combination of raw and boiled veggies and sprouts, seasoned with vinegar, lemon and olive oil, for your required dose of essential healthy fats.\nIt’s after this meal that your body is basically ready for heavy work outs, such …", "pred_label": "__label__POS", "pred_score_pos": 0.7247947454452515}
{"content": "Green Bonds: Effectiveness and Implications for Public Policy\nYou may be able to download this chapter for free via the Document Object Identifier.\nThis paper studies green bonds, a relatively new instrument in sustainable finance. I first describe the market for green bonds and characterize the \"green bond boom\" witnessed in recent years. Second, using firm-level data on green bonds issued by public companies, I examine companies' financial and environmental performance following the issuance of green bonds. I find that the stock market responds positively to the announcement of green bond issues. Moreover, I document a significant increase in environmental performance, suggesting that green bonds are effective in improving companies' environmental footprint. These findings are only significant for green bonds that are certified by independent third parties, suggesting that certification is an important governance mechanism in the green bond market. I conclude by discussing potential implications for public policy.\nI am grateful to Matthew Kotchen and Catherine Wolfram, as well as participants at the NBER Conference on Environmental and Energy Policy and the Economy for helpful comments. The views expressed herein are those of the author and do not necessarily reflect the views of the National Bureau of Economic Research.", "pred_label": "__label__POS", "pred_score_pos": 0.9370483756065369}
{"content": "Winter Park Government Negligence Lawyer\nPursuing a claim for government negligence is a unique process. It differs in many ways from standard personal injury and liability claims. Government agencies and entities are protected under a sovereign or governmental tort immunity. That allows them to escape liability for any action or failure to act, even though they would’ve been held liable if they acted as a private individual or entity. Given the restrictions on filing a claim for government negligence, you shouldn’t attempt to pursue a claim on your own.\nNo matter whether you are seeking damages from the city, county, state, or a federal entity, you need an experienced\nWinter Park government negligence lawyer who can help. At Israoui Law, we have years of experience pursuing government negligence claims. We understand the legal technicalities and time restrictions that must be strictly followed to pursue a claim successfully. We also know about notable exceptions that could lead the government to be held responsible. Exceptions to Government Negligence Immunity\nOne of the prime examples of exceptions to government negligence immunity involves auto accidents. If the vehicle is leased or owned by a government entity and is driven by an employee in the course and scope of their job, they could be held liable if they cause an accident. If there are hazardous road conditions, like a construction zone, that is not adequately marked or lit, you could have grounds to bring a claim for injuries and other damages.\nAs property owners, government entities have a duty to maintain their property to make it safe for those who enter the property. If you are a victim of a slip and fall or trip and fall accident at a public property, you could be entitled to recover compensation. Public property could include state roads, parking lots, county hospitals, sidewalks, municipal facilities, government buildings, etc.\nSlip and fall accidents can occur for various reasons, including wet floors, potholes, loose carpets or rugs, uneven floors, low lighting, or a lack of stair railings. If you were injured due to government negligence, you need to speak with an experienced Winter Park government negligence lawyer right away.\nPursuing a Claim for Government Negligence in Florida\nIf you don’t follow the strict rules for pursuing a claim against the government, it will be denied. You don’t have a lot of time to pursue a claim either. For example, you must file a notice of claim in writing with some agencies right away. If you don’t file the notice with the right agency and the Department of Financial Services, they will likely refuse the claim. Also, there are limits to how much you can recover and where the case must be filed if it goes to court.\nIt would be best if you spoke with an experienced Winter Park government negligence lawyer before speaking with any investigators or claims adjusters, signing any documentation, or agreeing to a settlement. Your attorney will protect your rights and the ability to recover compensation.\nIf you or a loved one were injured due to government negligence, contact Israoui Law to learn how we can help. We offer free, no-obligation initial consultations, so it costs you nothing to meet with us and determine whether you can pursue a valid claim for government negligence. We represent clients on a contingency fee basis. That means you won’t pay any fees or costs unless we successfully recover compensation on your behalf. Let us handle the stressful claims process while you concentrate on your recovery.", "pred_label": "__label__POS", "pred_score_pos": 0.8731502294540405}
{"content": "This project evaluated if storybooks help to teach children to eat more vegetables and fruit.\nTo evaluate the effect of a community-based, experiential cooking and nutrition education program on consumption of fruits and vegetables and associated intermediate outcomes in students from low-income families.\nThe aim of our study was to evaluate the efficacy and acceptability of a taste exposure-plus-reward intervention delivered through mailed materials and access to an online video.\nTo examine whether parents offering a sticker reward to their child to taste a vegetable the child does not currently consume is associated with improvements in children’s liking and consumption of the vegetable.\nThis study aimed to (1) investigate short-term effects and long-term effects of non-food rewards on liking and intake of a moderately disliked vegetable; and (2) to compare exposure without reward with no-exposure control.\nThe Healthy Habits trial aimed to assess the efficacy of a telephone-based intervention for parents to increase the fruit and vegetable consumption in their 3–5-y-old children.\nA cluster-randomized controlled-trial examined the effect of a school-based comprehensive intervention on nutrition knowledge, eating habits, and behaviors among low socioeconomic status school-aged children", "pred_label": "__label__POS", "pred_score_pos": 0.5329581499099731}
{"content": "In this latest blog focussed on business management, we examine, how in this modern information-driven world, data is progressively being recognised by CEOs as a critical business investment and asset and why it is increasingly coming to the forefront of business valuations as never before.\nWe also explore how Customer Relationship Management (CRM) solutions can help, not only in managing your data, but adding value to this critical business asset.\nWe chat with one of our Maximizer CRM customer’s, who with early insight, has already achieved this goal within his own business.", "pred_label": "__label__POS", "pred_score_pos": 0.716206431388855}
{"content": "Description\nThe Eley cartridges contain an average of 184 pellets. They contain a short fibre wad but no nitro card or driving wad. Unlike their supersonic counterparts, they are crimped with a 6-point star closure. The case is a standard 3″ parallel tube plastic case, supplied in red with Eley branding printed in black.\nRecoil\nThe subsonic Eley “Extralong” produces moderate recoil (even for a .410 loading) as would be expected of a low velocity cartridge. However, it is not, interestingly, the lightest-recoiling cartridge which the team at SmallBoreShotguns have tested, producing slightly more kick than the Lyalvale “Supreme Game” cartridge previously tested. This is lack of a nitro card / driving wad in the cartridge is notable in this regard.\nInstinctively, one would expect pressures and recoil to be lower in a “fibre wad only” cartridge given that obturation will be less good. In these cases, some combustion gases would be expected to pass around the wad, lengthening the time over which the gas escapes from the muzzle and reducing the rate of acceleration of the gun into the firer’s shoulder. This should, in turn, reduce perceived recoil as the recoil energy will be absorbed over a longer time period. However, it is already suspected that the Lyalvale cartridge uses a high-volume, slow-burning powder, which may be the basis for these observations.\nPerformance\nUse of the subsonic cartridge in the field has been limited, but broadly successful. The cartridge has already accounted for one testing 40-yard wood pigeon and several other shorter-range birds. Kills have been clean, albeit slightly less “definitive” than – for example – a bird hit with 1¼oz of #5 at medium range. Initial patterning showed promising results out to 30 yards, with the 40-yard patterns looking a little sparse.", "pred_label": "__label__POS", "pred_score_pos": 0.7105636596679688}
{"content": "Interns, Hannah Magnuson and Shannon O’Malley\nAs members of the millennial generation, we often define “socializing” as synonymous with hunching over our smartphones. A day spent texting, tweeting, and FaceTiming friends from out-of-town is considered a day with heavy communication. However, when it comes to the workroom, we millennials may need to learn that in-person communication still holds value and cannot be completely replaced by the newest technology, no matter how convenient.\nIn his Chicago Tribune column, “Millennials eager to lead and would welcome help,” Rex W. Huppke cites Pew Research Data which says 18-34 year-olds have overtaken the workplace. While these millennials are reportedly eager to become leaders, there remains a rift in how their current skillsets will translate to leadership positions. As interns we regularly send texts to subordinates, equals and superiors because sometimes shooting out a text is easier than emailing. Millenials, like us, tend to assume that all professionals check their texts as frequently as we do. Can we successfully lead veterans of the workforce while utilizing communication methods that these older generations have not yet embraced?\nRecently, “The Millennial Leadership Study” found that the overwhelming majority of millennials strive for leadership roles and cite “communication” as their strongest tool to attain their goal of assuming leadership positions. Their main goal is to empower others as opposed to making money, a selfless ambition that has been absent in the workforce for quite some time. However, their definition of “communication” is comprised of social media shout-outs, and lacks a personal touch. While the ability to send out a cleverly crafted and wide-reaching Tweet is a useful skill, these new workers need to learn that face-to-face communication remains invaluable.\nGuidance from more experienced workers will be necessary to teach that communication encompasses much more than exchanging words from behind a screen. Millennials trying to lead older generations by means of advanced forms of communication will soon learn that they cannot obtain experience of Generation X and the Baby Boomers by reading about them on the World Wide Web. Instead, they may wish to try sitting down and having a conversation.\nThese generations must learn from one another how to establish a balance between communication and technology. If their staunch differences prevent them from working together, it will lead to chaos, miscommunications and eventual crises. As millennials redefine their conceptions of what it takes to be a leader, their abilities to respond positively to their coworkers’ feedback will be paramount.\nEven in an age where text messages, Twitter, and FaceTime dominate the social sphere, the power of face-to-face interactions and constructive feedback will never be outdated. The sooner we millennials learn to look up from our phones, the sooner we might attain our desired leadership roles.", "pred_label": "__label__POS", "pred_score_pos": 0.5056636929512024}
{"content": "Tackling Sustainable Development Goals with Earth observation data\nNovember 2019 saw G-STIC 2019 organised by our partner VITO take place in Brussels – the\nGlobal Sustainable Technology and Innovation Conference. As part of this event, Copernicus, the EU’s Earth Observation programme, organised the Sustainable Development Goals Copernicus Hackathon. The aim of this hackathon was for participants to develop new software solutions based on Copernicus Earth Observation (EO) data for one of three societal challenges: ‘Healthy lives for all’, ‘Nutritious food for all’ and ‘Raw materials in a circular economy’. Teams brought together participants from different backgrounds, including entrepreneurs, coders, researchers, scientists, EO specialists, designers, storytellers and more. A different challenge was set for each theme, but prizes were awarded for the best solutions presented across all three challenges.\nThe Raw Materials in a Circular Economy challenge was to\nDevelop Acid Mine Drainage monitoring possibilities using Copernicus Sentinel-2 data on mine tailings at Yxsjöberg in central Sweden. The Acid Mine Drainage challenge had to be solved using Copernicus Sentinel-2 satellite observations. This data is globally and freely available with a high temporal revisit rate and spatial resolution. EIT RawMaterials Innovation Community takes the 1st & the 2nd place in the Sustainable Development Goals Copernicus Hackathon\nThose tackling this challenge included six participants from the EIT RawMaterials supported\nRawMatCop project, and six participants from the EIT-Labelled SINReM International Master in Sustainable and Innovative Natural Resource Management. Winning the first prize of €3,000 and a seat on the Copernicus Accelerator, was the ExaMine team, which included two SINReM students, . Mridul Pareek and Antonio Mires In second place was the RawMatCop team, which developed the AcidmApp solution. This team, which was awarded a prize of €2,000 and assistance with enrolment for a position in the Astropreneurs’ programme, included two RawMatCop researchers, Louis Andreani and Jingyi Jiang, as well as four graduates of the RawMatCop Academy.\nThe Sustainable Development Goals Copernicus Hackathon was a great opportunity to spread the word about the applications of Copernicus data to the raw materials sector. That both first and second prizes were awarded to teams tackling the raw materials challenge, really emphasises the potential of Earth observation data to make the raw materials industry more sustainable.\nIrene Benito, RawMatCop Manager at EIT RawMaterials\nYou can stay up-to-date with developments in Earth observation for raw materials and the RawMatCop programme by following RawMatCop on Twitter.", "pred_label": "__label__POS", "pred_score_pos": 0.5923525094985962}
{"content": "Purchase this article with an account.\nor\nVy Vo, David Sutterer, Joshua Foster, Thomas Sprague, John Serences, Edward Awh; Neural representations of spatial position recalled from long-term and short-term memory diverge across the cortical hierarchy. Journal of Vision 2017;17(10):1115. doi: https://doi.org/10.1167/17.10.1115.\nDownload citation file:\n© ARVO (1962-2015); The Authors (2016-present)\nHolding an item in short-term memory (STM) elicits stimulus-specific representations across sensory, parietal, and frontal cortex (Ester, Sprague, Serences 2015). Recent evidence suggests that retrieving items from long-term memory (LTM) also reinstates neural representations in sensory cortex (Bosch et al. 2014). However, it remains unknown how sensory representations of items from LTM and STM differ in their distribution across these areas of human cortex. Here, we directly compared neural representations of locations that were retrieved from LTM or maintained in STM, and assessed how these neural measures tracked behavioral precision. We trained subjects to associate 24 unique clip art items with spatial positions along an isoeccentric ring (Sutterer & Awh, 2015). In subsequent training days, subjects performed both a LTM task to retrieve the learned pairings and a STM task which required subjects to maintain a spatial position in STM. The precision of subjects' LTM recall plateaued after ~5 days of training, with precision that approached STM performance. We then acquired fMRI while subjects performed both tasks in the scanner. On separate runs, we obtained data to train an inverted encoding model (IEM) for spatial position. This allowed us to reconstruct the spatial location of each item as it was being held in memory (e.g., during a stimulus-absent delay period; Sprague et al. 2014; Ester et al. 2015). We successfully reconstructed the position of the remembered stimulus during the delay period of both tasks. STM representations were more robust than LTM representations in early sensory areas. However, the difference between the fidelity of STM and LTM representations decreased in later sensory areas. Overall, our data suggest that changes in the relative representations of items stored in STM and LTM across the visual hierarchy likely support the precision of LTM recall.\nMeeting abstract presented at VSS 2017\nThis PDF is available to Subscribers Only", "pred_label": "__label__POS", "pred_score_pos": 0.6119940280914307}
{"content": "In mammals, the electron transfer flavoprotein (ETF) is a heterodimeric protein composed of two subunits, alpha and beta, that is responsible for the oxidation of at least nine mitochondrial matrix flavoprotein dehydrogenases. Electrons accepted by ETF are further transferred to the main respiratory chain via the ETF ubiquinone oxide reductase (ETFQO). Sequence analysis of the unique Arabidopsis homologues of two subunits of ETF revealed their high similarity to both subunits of the mammalian ETF. Yeast two-hybrid experiments showed that the Arabidopsis ETFalpha and ETFbeta can form a heteromeric protein. Isolation and characterization of two independent T-DNA insertional Arabidopsis mutants of the ETFbeta gene revealed accelerated senescence and early death compared to wild-type during extended darkness. Furthermore in contrast to wild-type, the etfb mutants demonstrated a significant accumulation of several amino acids, isovaleryl CoA and phytanoyl CoA during dark-induced carbohydrate deprivation. These phenotypic characteristics of etfb mutants are broadly similar to those that we observed previously in Arabidopsis etfqo mutants, suggesting functional association between ETF and ETFQO in Arabidopsis, and confirming the essential roles of the ETF/ETFQO electron transfer complex in the catabolism of leucine and involvement in the chlorophyll degradation pathway activated during dark-induced carbohydrate deprivation.", "pred_label": "__label__POS", "pred_score_pos": 0.998190701007843}
{"content": "This article is an attempt to answer the question: Where does a classical narrative beginning end? It examines a series of epistemological concerns about the nature of beginnings before exploring two previous models that can be used to determine where a narrative beginning ends, one by Kristin Thompson that relies primarily on a narrative's formal properties, and one by James Phelan that relies primarily on cognitive processes. The article focuses primarily on the possibilities for a cognitive model for determining the end of a narrative beginning. However, ultimately, it argues that only by combining formal properties and cognitive processes can we arrive at a comprehensive and flexible model for how to determine where a classical narrative beginning ends.", "pred_label": "__label__POS", "pred_score_pos": 1.0000098943710327}
{"content": "How can organisations explore data to learn more about their customers, usage trends, and preferences? How can they identify new patterns of behaviour, to personalise services, or produce more granular management reports?\nWith the explosion of data, enterprises are finding countless opportunities to obtain valuable insights across the board and, with them, they’re also encountering growing strategic and operational challenges.\nTo unlock the power of big data and harness the potential of AI and ML, organisations need a strategy for managing their data in the long term. This demands a modernisation path.\nChoosing the right infrastructure solution and partner to enable staff to slice, dice, and analyse their data is critical: it’s both a strategic and operational decision.\nThis report explores the current data management landscape, barriers to adopting cloud infrastructure and critical factors organisations need to keep in mind to choose the right cloud provider for their business needs.", "pred_label": "__label__POS", "pred_score_pos": 0.7051851749420166}
{"content": "Description H2 Elite Creates hydrogen infused magnesium water which converts toxic oxygen radicals to water. Hydrogen infused water supports the body’s antioxidant levels, including glutathione. Electrolyte minerals in Original Quinton formulas may help increase energy, endurance, and recovery. Supports the immune system. Helps with relaxation and sleep. Supports detoxification and antioxidation.\nOverall Health Combo Pack Contains:\n1 each Quicksilver Scientific H2 Elite 1 each Original Quinton Hypertonic Marine Plasma 2 each Quinton Isotonic Marine Plasma Quicksilver Scientific H2 Elite, Creates Hydrogen Infused Alkaline Water, 60 Tablets\nMolecular Hydrogen instantaneously converts toxic oxygen radicals to water. It maintains stable levels of our body’s antioxidants (e.g. glutathione). It promotes cell signaling, cell metabolism, & gene expression which promotes increased health.\nOriginal Quinton Hypertonic Marine Plasma, 30 Count, from Spain\nQuinton Hypertonic Marine Plasma represents the original blueprint of life. It has three times the mineral concentration of your blood and is ideal for energizing, mental focus, sports performance, challenged immune systems, and rapid re-mineralization.\nOriginal Quinton Isotonic Marine Plasma, 30 Count, from Spain\nQuinton Isotonic is pure marine plasma diluted to match the concentration of your blood and is the most gentle. Bioterrain Restore is ideal if for a sensitive system, restoration, deeper sleep, emotional and physical balance, and relaxation.\nWarnings: If pregnant, nursing, or undergoing treatment for a medical condition, consult your physician before taking this product Keep out of reach of children Do not exceed recommended dose\n* These statements have not been evaluated by the Food and Drug Administration. This Product is not intended to diagnose, treat, cure or prevent any disease.", "pred_label": "__label__POS", "pred_score_pos": 0.5532110333442688}
{"content": "In this outdoor activity, learners explore how a surprising number of animals use human-made litter, such as cans and crumpled paper, to find food and shelter in their environment. Based on what they observe, learners are asked to make a value judgment about litter. This activity can be combined with a litter cleanup in a local park, schoolyard or other location.", "pred_label": "__label__POS", "pred_score_pos": 0.8002598881721497}
{"content": "As unemployment claims skyrocket amid the COVID-19 crisis, this analysis finds most people who lose their job-based coverage are likely eligible for subsidized coverage through the ACA marketplaces or Medicaid.\nIndividual market insurers, on average, remained profitable through the first three months of 2020 as claims costs rose only slightly compared to the same period last year.", "pred_label": "__label__POS", "pred_score_pos": 0.9982189536094666}
{"content": "Refining the Categorization of Physical Functional Status\nThe Added Value of Combining Self-Reported and Performance-Based Measures.\nPublished in: Journal of Gerontology, Series A: Biological Sciences and Medical Sciences, v. 59, no. 10, 2004, p. 1056-1061\nPosted on RAND.org on January 01, 2004\nBACKGROUND: When considered individually, self-reported functional status and performance-based functional status predict functional status decline and mortality. However, what additional prognostic information is gained by combining these approaches remains unknown. METHODS: The authors used three waves of three sites (5138 participants) of the Established Populations for Epidemiologic Studies of the Elderly to determine the prognostic value of individual and combined approaches. Baseline self-reported (mobility and activities of daily living [ADL] items) and performance-based (Physical Performance Score) functional status information was classified into three and four hierarchical categories, respectively. RESULTS: Based on self-reported information alone, at 1 year, 73% participants had not changed, 15% declined, 6% improved, and 6% died. At 4 years, 53% had not changed, 24% declined, 2% improved, and 22% died. Based on performance-based assessment alone, at 4 years, 33% of the sample remained stable, 37% declined, 6% improved, and 24% died. In the top two self-reported categories, functioning on the performance-based assessment varied widely. Among those who were independent in all self-reported functioning, approximately 40% scored in each of the top two performance-based categories. Among persons in the top two self-reported categories, poorer performance was associated with progressively higher 1-year and 4-year mortality rates. Among persons with impaired mobility and at least 1 ADL dependency, the mortality rate was high and was not influenced by performance-based score. CONCLUSIONS: Combining self-reported and performance-based measurements can refine prognostic information, particularly among older persons with high self-reported functioning. However, if ADL dependency is present, performance-based measures do not add prognostic value regarding mortality.", "pred_label": "__label__POS", "pred_score_pos": 0.8068566918373108}
{"content": "Abstract\nIn this study we assessed the dietary phytochemical index in relation to the risk of breast cancer in women.This case-control study was conducted on 100 incident breast cancer cases and 175 healthy controls. Dataregarding socio-demographic factors, medical history, medications, and anthropometric measurements werecollected. Dietary data were obtained using a validated food frequency questionnaire and a energy-adjusteddietary phytochemical index (PI) was calculated. The odds ratios of breast cancer were assessed across energyadjustedPI quartile categories. The mean age of participants was 46.2±8.9 and 45.9±9.4 years in cases andcontrols, respectively. The mean PI across quartile categories was 13.9±2.6, 21.1±1.8, 26.7±2.1, 41.6±10.2 in thefirst, second, third and fourth quartiles, respectively. After adjustment for all potential confounders, the riskof breast cancer in the forth quartile of dietary PI was significantly decreased (OR=0.08, 95%CI=0.01-0.84).Higher intake of phytochemical-rich foods is associated with lower risk of breast cancer.\nKeywords", "pred_label": "__label__POS", "pred_score_pos": 0.6356610059738159}
{"content": "Kent McGuire – OSU Ag Safety and Health Coordinator\nOne of the most common tasks on the farm is hitching or unhitching equipment. The two most common tractor-hitching methods use the drawbar or the 3-point hitch assembly. In either case, there can be multiple elements involved in the process including: connecting the implement using a hitch pin, adjusting a jack stand, attaching safety chains, connecting the PTO shaft, connecting hydraulic couplings, or plugging in electrical connections. Common injuries during hitching are caused by pinch points, crush points, blunt trauma, and run-over. General safety guidelines to follow when hitching or unhitching equipment include:\n- Review the operator manual of the tractor and implement before use.\n- Ensure hitch attachments match the tractor hitch category.\n- Assess the situation and make a plan prior to attempting to hitch the implement.\n- Ensure any bystanders are all clear of the tractor and implement.\n- Place the tractor in a lower gear and lower the RPMs to reduce sudden quick movements when approaching or pulling away from the implement.\n- When assisting the operator, keep visual contact and communicate with the operator at all times.\n- The ground person should stay outside of the wheels of the tractor until the hitch and drawbar are lined up correctly.\n- Leave yourself an escape route. Plan a travel path to get out of the way should the tractor lurch towards you.\n- Once the hitch and implement are lined up, make sure the tractor is in PARK and shut off the engine before installing the hitch pin or completing additional hitching tasks such as connecting PTO or hydraulic lines.\n- Use only approved hitch pins. If hitch pins are damaged or bent, take them out of service.\n- Make sure the hitch pin is locked in place or secured with a hitch pin clip.\n- Before connecting or disconnecting hydraulic lines, ensure the pressure has been released from the system.\n- Use proper lifting techniques to reduce sprains / strains when lifting or moving the implement tongue.\n- Ensure there is sufficient tongue weight to stabilize the implement when unhitching.\n- Use an approved size tongue jack to support the tongue weight of the implement.\n- Only use jacks that are attached to the tongue. Temporary jacks can kick out or fail with minimal implement movement.\n- Remove all additional connections prior to pulling away from equipment.\n- When unhitching on slopped areas, chock the wheels of the implement to prevent unwanted movement.", "pred_label": "__label__POS", "pred_score_pos": 0.9891290664672852}
{"content": "Remote learning - Wellbeing\nIt’s crucial to support young people to manage and maintain good wellbeing. The activities below can help young people in a range of settings to develop coping strategies and maintain a positive attitude, and include Interactive worksheets and Online lesson films (interactive film tutorials), adapted from LifeSkills lesson plans. You’ll also find a full length lesson plan on the same themes on each page, which can support classroom and group sessions.\nThe worksheets can be downloaded and shared with students as independent learning activities, as homework, or to complement the relevant lesson plans.\nThe Online lesson films around the topic of wellbeing have been created to give students practical tips for managing their own wellbeing while under pressure. They can be used alongside the interactive worksheets on the same page, or on their own.\nA free account gives you access to all educator content, tools and resources\nOver 85,000 educators use LifeSkills’ free and immediately accessible resources to guide young people. Join them in less than 5 minutes.\nAlready have an account?Log in Get started Thank you for liking\nHelp us to continue creating relevant content for you by leaving some additional feedback.", "pred_label": "__label__POS", "pred_score_pos": 0.9260605573654175}
{"content": "After over two months of fighting in southern Tripoli areas, people are suffering from a lack of services in all fields.\nThe political instability and violence within these regions have created a hindrance for service companies due to increasing the difficulty of reaching war zones.\nThe damaged infrastructure as well as the continuous attacks suffered have created several obstacles.\nYet, some companies still managed to push through. Firms providing services across districts with crossfires face several challenges as there are many barriers and unforeseeable risks.\nAmong such companies is Giga ltd. for telecommunications and technology. Giga has managed to provide internet to Abu Salim, Ain Zara, and Qasir Benghashir after fiber cables were damaged by clashes.\nThe company provided internet services through a wireless connection, overcoming the drawbacks of fiber cables, supporting people in dire need.\nGiga is a tech and telecommunication pioneer providing several services in Libya. Moreover, It has received a franchise from Ubiquiti Networks – the largest wireless internet equipment distributor.", "pred_label": "__label__POS", "pred_score_pos": 0.9658770561218262}
{"content": "Housing First (HF) aims to overcome homelessness by offering immediate, independent accommodation in the community. In doing so, the model seeks to provide a foundation for client centred support that enables recovery from the ‘multiple and complex’ needs that multiply excluded homeless (MEH) adults experience. The majority of HF literature has focussed on the model’s very positive housing related outcomes. However, outcomes related to recovery and desistance have been less clear. This article draws on a qualitative, longitudinal evaluation of a HF service in a northern English city, following 18 MEH adults over 16 months in their HF tenancy. A situational approach was used to explore participants’ ability to utilize the foundation provided by HF achieve outcomes related to recovery and desistance. Findings demonstrated the importance of participants’ biographies in determining their ability to progress towards these outcomes. A key output of the article is a typology of participant’s biographies that was predictive of their trajectories in HF.", "pred_label": "__label__POS", "pred_score_pos": 0.9969834685325623}
{"content": "The playAWARDS team engaged with marketing leaders at each of the company’s Las Vegas resorts, along with the corporate marketing team. Together, they developed a program to create a comprehensive, gamified expression of the MGM portfolio. This program included themed slot machines, in-game challenges, and a curated collection of promotional offers designed to help MGM properties take advantage of surplus resort capacity and drive consumption of perishable inventory. Because players earn these awards through an investment of time and energy playing a game, the value of these offerings elevate the MGM brands. By contrast, dumping discounted inventory diminishes their perceived value.\nWith the program up and running, the playAWARDS team and MGM business analysts began to track its performance. What they discovered was that MGM Resorts was able to drive new incremental revenue and capture a meaningful return over and above the cost of their offers.\nIn addition, MGM found that the playAWARDS program was not only attracting a new audience but was helping them engage more deeply with existing customers while reactivating lapsed or dormant customers. The end result delivered on the playAWARDS promise—giving MGM Resorts a fresh, exciting, and highly efficient way to extend their market leadership.", "pred_label": "__label__POS", "pred_score_pos": 0.853108286857605}
{"content": "Abstract\nChest pain in children and adolescents frequently involves referral to a pediatric cardiologist. The etiology of chest pain in pediatrics is broad, and the vast majority of cases are not due to underlying cardiac pathology. However, evaluations are often pursued due to fear about missing a potentially serious cardiac diagnosis, which may lead to sudden cardiac death. The management of these patients can lead to extensive investigations, medical visits, and hospitalizations, which is costly and unnecessary in many cases. This article reviews noncardiac and cardiac etiologies of chest pain, highlights pertinent details of the patient history and physical examination, discusses the evaluation of patients with chest pain, and identifies when referral to a pediatric cardiologist is recommended.\nASJC Scopus subject areas Pediatrics, Perinatology, and Child Health", "pred_label": "__label__POS", "pred_score_pos": 0.9990125298500061}
{"content": "Motivated by the recent discoveries of binary black-hole mergers by the Advanced Laser Interferometer Gravitational-wave Observatory (Advanced LIGO), we investigate the prospects of ground-based detectors to perform a spectroscopic analysis of signals emitted during the ringdown of the final Kerr black-hole formed by a stellar mass binary black-hole merger. Although it is unlikely that Advanced LIGO can measure multiple modes of the ringdown, assuming an optimistic rate of 240 Gpc\\(^{-3}\\)yr\\(^{-1}\\), upgrades to the existing LIGO detectors could measure multiple ringdown modes in \\(\\sim\\)6 detections per year. New ground-based facilities such as Einstein Telescope or Cosmic Explorer could measure multiple ringdown modes in over 300 events per year. We perform Monte-Carlo injections of \\(10^{6}\\) binary black-hole mergers in a search volume defined by a sphere of radius 1500 Mpc centered at the detector, for various proposed ground-based detector models. We assume a uniform random distribution in component masses of the progenitor binaries, sky positions and orientations to investigate the fraction of the population that satisfy our criteria for detectability and resolvability of multiple ringdown modes. We investigate the detectability and resolvability of the sub-dominant modes \\(l=m=3\\), \\(l=m=4\\) and \\(l=2, m=1\\). Our results indicate that the modes with \\(l=m=3\\) and \\(l=2, m=1\\) are the most promising candidates for sub-dominant mode measurability. We find that for stellar mass black-hole mergers, resolvability is not a limiting criteria for these modes. We emphasize that the measurability of the \\(l=2, m=1\\) mode is not impeded by the resolvability criterion. To optimize the senstivity of a detector for ringdown signals, sensitivity should be tuned to the 300 to 500 Hz region.", "pred_label": "__label__POS", "pred_score_pos": 0.6446947455406189}
{"content": "NCASE Resource Library Featured Resources\nThis publication features some of the best resources, including webinars, briefs, and toolkits, available in the online NCASE Resource Library, developed for both practitioners and system builders.\nThese selected resources, curated by NCASE, offer ideas and information for OST system leaders to support recovery from COVID-19.\nThe NCASE Out-of-School Time Professional Development System-Building Toolkit was designed to assist states as they build professional development systems inclusive of school-age providers.\nSearch for Resources ? Search Results Filter By Reset Selections Expand All Filters Topics Resource type Publisher Search Results Filter By\nThe Afterschool Alliance's webpage on COVID-19 offers a rich array of resources to help support Out-of-School Time (OST) system builders, administrators, and practitioners in navigating the challenges of the pandemic as they strive to effectively serve children, families, and providers.\nThis report captures what was shared at an October 2019 Conference about the challenges of teaching social and emotional learning (SEL) in afterschool programs. It provides a brief history of the growing focus on SEL, along with a summary of remarks by national leaders.\nThis report offers information to aid summer learning leaders in securing and maintaining support for programs. It summarizes lessons learned from interviews with 60 school district staff and 20 policy experts on federal, state, city, and district funding and policies.\nThis classic report clarifies the cost of quality out-of-school time programs, based on data from 111 quality programs in six cities. It provides the mean and range for hourly and daily cost per slot, with an analysis of factors that bring differences to cost.\nThe Afterschool Alliance has developed an easy-to-use searchable database on evidence-based impacts of afterschool and summer programs.\nThis report summarizes 2014 survey results and provides a quick picture of supply and demand in afterschool. It indicates that the numbers of children being served in afterschool have increased to 10.2 million. It also indicates that the numbers of children that would enroll if a program were available is increasing to 19.4 million.\nThis special report focuses on the potential of afterschool and summer programs to support families living in communities of concentrated poverty. It outlines both benefits of Out-of-School (OST) programs and barriers to enrollment for families from resource-poor backgrounds. It offers recommendations to system builders and providers.\nThis website offers afterschool nonprofits a range of tools, articles, reports, and resources to develop financial skills. It includes articles, webinars, videos, and self-assessment resources on planning, operations, monitoring, and governance.\nThis website provides resources on program planning, managing staff and volunteers, planning lessons, technology, and materials using a real-life, project-based approach to learning. The website includes sections on digital storytelling, inquiry-based learning, youth media training, fostering positive climates, and nurturing creativity.\nThis guide describes how cities and intermediaries can work with afterschool providers across a neighborhood, city, or region to build quality. It explores how to identify a lead organization, engage stakeholders, use a continuous improvement model, and manage data systems. It includes case studies from Georgia, Texas, Illinois, Massachusetts, New York, and Florida.", "pred_label": "__label__POS", "pred_score_pos": 0.9480509161949158}
{"content": "Quantitative trait loci (QTL) analyses in pig have revealed numerous individual QTL affecting growth, carcass composition, reproduction and meat quality, indicating a complex genetic architecture. In general, statistical QTL models consider only additive and dominance effects and identification of epistatic effects in livestock is not yet widespread. The aim of this study was to identify and characterize epistatic effects between common and novel QTL regions for carcass composition and meat quality traits in pig. Methods Five hundred and eighty five F 2 pigs from a Duroc × Pietrain resource population were genotyped using 131 genetic markers (microsatellites and SNP) spread over the 18 pig autosomes. Phenotypic information for 26 carcass composition and meat quality traits was available for all F 2 animals. Linkage analysis was performed in a two-step procedure using a maximum likelihood approach implemented in the QxPak program. Results A number of interacting QTL was observed for different traits, leading to the identification of a variety of networks among chromosomal regions throughout the porcine genome. We distinguished 17 epistatic QTL pairs for carcass composition and 39 for meat quality traits. These interacting QTL pairs explained up to 8% of the phenotypic variance. Conclusions Our findings demonstrate the significance of epistasis in pigs. We have revealed evidence for epistatic relationships between different chromosomal regions, confirmed known QTL loci and connected regions reported in other studies. Considering interactions between loci allowed us to identify several novel QTL and trait-specific relationships of loci within and across chromosomes.", "pred_label": "__label__POS", "pred_score_pos": 0.6857573986053467}
{"content": "A reader must ask if an RNA molecule could possibly govern chemical reactions, suppress free-riders, support co-operators, and act in its own self-interest.\nProfessor Hansma maintains that sets of integrated reactions could have been directed by natural selection to gradually evolve into an autonomous cell.\nDoes the universe bear a “stamp” indicating the guidance of a designing intelligence? Lennox’s answer is yes. He has spent a lifetime arguing as much.\nHow do you get a 3-D shape from a linear code? That is the puzzle of morphogenesis.\nIf the paper is any indication, appearing as it does in a prominent journal, some of the suffocating constraints on ID advocacy may be coming off.", "pred_label": "__label__POS", "pred_score_pos": 0.9974324703216553}
{"content": "MAP FinTech, in conjunction with its UK strategic partner, Complyport, is taking all the necessary actions to inform financial firms about Brexit and how this unparalleled event might potentially impact financial services across Europe. As we are inching closer to Brexit’s deadline, we have prepared a survey to gather information on the steps being taken by financial institutions when this becomes reality. This effort will also include sharing the findings with its participants so they are aware of how other financial institutions are preparing for Brexit.\nWith this in mind, financial firms need to consider that they will be facing unique challenges and conditions that may require both a new understanding of our industry and advanced planning in order to avoid the many uncertainties that may lead to undesirable consequences.\nThrough the power of synergy, this survey aims to prepare financial firms to face the potential risks that a “hard” Brexit scenario may bring to an already challenging 2020.\nPlease complete the survey below and stay informed on how the UK financial services sector is preparing to transition into a post-Brexit Europe in the smoothest way possible.", "pred_label": "__label__POS", "pred_score_pos": 0.9546974301338196}
{"content": "Abstract\nThe aim of the study was to investigate the effectiveness of a brief robot-mediated intervention based on Lego(A (R)) therapy on improving collaborative behaviors (i.e., interaction initiations, responses, and play together) between children with ASD and their siblings during play sessions, in a therapeutic setting. A concurrent multiple baseline design across three child-sibling pairs was in effect. The robot-intervention resulted in no statistically significant changes in collaborative behaviors of the children with ASD. Despite limited effectiveness of the intervention, this study provides several practical implications and directions for future research.\nKeywords ASD; Children; Robot-intervention; Lego (R) therapy; Collaborative play KeyWords Plus:HIGH-FUNCTIONING CHILDREN; SOCIAL-SKILLS; YOUNG-CHILDREN", "pred_label": "__label__POS", "pred_score_pos": 0.998368501663208}
{"content": "Certain individuals appear to succeed against all odds. Despite severe hardships such as living through war, witnessing the death of a loved one, having a chronic illness, being a victim of abuse or dealing with unemployment, certain people not only adapt but actually thrive. These people possess a quality known as “resilience.” This workshop will examine the characteristics of resilience and discover ways to introduce greater resilience into our lives.\nThis workshop is targeted to anyone who would like to understand resilience more fully and learn how to improve their capacity to thrive despite adversity.\nWorkshop Objectives\nAt the end of this workshop, you will be able to:\nDescribe what resilience really is\nDescribe the concept of resilience as it relates to children and adults Describe the characteristics of resilient people Describe how emotional control, self-awareness and strong relationships relate to resiliency\nIdentify your own resilient capacities\nIdentify your unique resilient strengths and areas for development Recognize which situations are most stressful\nDescribe resilience building strategies\nDescribe techniques to enhance resilience through changing your perception, taking decisive action and engaging in appropriate self care. Event Details When: Time: 09:00 AM - 10:00 AM CST Location: Webinar", "pred_label": "__label__POS", "pred_score_pos": 0.5946626663208008}
{"content": "In Colombia, interurban road freight transport is characterized by a very old vehicle fleet with an average age of 18 years, a low level of business development and inefficient logistic operations. The limited financial resources of the numerous small logistic providers reinforce the steady ageing of the vehicle fleet. The NAMA has aims to reduce and rejuvenate the vehicle fleet, to promote the development of modern freight transport businesses, and to enhance the efficiency of logistic operations.\nThis publication explains the scope of the NAMA, its motivation and objective, supporting measures, the mitigation potential and co-benefits, and funding.", "pred_label": "__label__POS", "pred_score_pos": 0.8475250005722046}
{"content": "Gas/Electricity Sectors Coupling FTI Consulting was commissioned to conducta review, based on interviews with marketparticipants, aimed at highlighting the mainbarriers to gas/electricity sectors coupling andproviding possible solutions that could be readilyimplemented. The recommendations made byFTI Consulting in this study were submitted tothe European Commission by the association GIE(Gas Infrastructure Europe). Situation\nThe European Commission requested policy recommendations on Sector Coupling from industry participants, which prompted the need to have a fact-based review of the existing barriers to gas/electricity sectors coupling.\nOur Role\nFTI-CL Energy was commissioned to conduct a review of some of the key barriers to sector coupling based on personal interviews with market participants. Based on numerous interviews, we synthesized the views from the industry in four dimensions (Market design barriers, Regulatory barriers, Technical barriers, and Governance barriers), stemming separately to Gas-to-Power and Power-to-Gas. Beyond the mapping of the key barriers, we also analyzed the practical potential solution that could be implemented to alleviate the issue.\nOur Impact\nGIE included our study in its submission to the European Commission, as a public contribution to the debate on policy design, which is available here.", "pred_label": "__label__POS", "pred_score_pos": 0.5061688423156738}
{"content": "We want to share some of our thoughts on the matter:\nMobile phones offer affordable, proximate, personalized, and continuous measurement and interaction, supporting chronic disease prevention and management as part of daily life, 24×7. The data streams generated by mHealth applications contribute simultaneously to three essential feedback loops: participant self-care, clinical care, and research evidence. The most significant innovation bottleneck is the slow evolution and validation of sensemakingtechniques for extracting and evaluating relevant data features and patterns to drive these feedback loops.\nOpenmhealth.org aims to catalyze an open community and bootstrap rapid cycles of design, deployment, learning, sharing, and evidence generation; allowing innovators and entrepreneurs to focus on their unique market offerings while increasing the validity, robustness and efficiency of shared components and methods.\nTogether we want to flip the direction of research inference on its head, generating population-level evidence from personal evidence, rather than the other way around.", "pred_label": "__label__POS", "pred_score_pos": 0.9963994026184082}
{"content": "Close to two-thirds of the world's poorest people live in rural areas. Eradication of rural poverty depends on increased access to goods, services, and information, targets detailed in the United Nations Millennium Development Goals. However, alleviating poverty is hindered by two interlinked phenomena: lack of access to improved energy services and worsening environmental shocks due to climate change. Mitigating climate change, increasing energy access, and alleviating rural poverty can all be complementary, their overlap defining an energy-poverty-climate nexus.", "pred_label": "__label__POS", "pred_score_pos": 0.9990915656089783}
{"content": "Inpatient Vs. Outpatient If you are seeking treatment for addiction, one of the initial decisions you will need to make is whether to participate in an inpatient vs. outpatient treatment program. Each approach has its advantages, share many of the same features, and can be highly effective. However, each person and their needs are unique, and therefore, and one program might ideal for some but not for others. Residential Inpatient Treatment Many people engaging in addiction treatment choose to participate in a residential […]", "pred_label": "__label__POS", "pred_score_pos": 0.7411708831787109}
{"content": "University of Göttingen) Vegetable oil biofuels are increasingly used as an alternative to fossil fuels despite the growing controversy regarding their sustainability. In a study led by the University of Göttingen, researchers investigated the effect of palm-oil biodiesel on greenhouse gases for the entire life cycle. They found that using palm oil from first rotation plantations where forests were cleared for palms leads to an increase in greenhouse gas emissions compared to fossil fuels. The results were published in Nature Communications.\n(", "pred_label": "__label__POS", "pred_score_pos": 0.746188759803772}
{"content": "The RFS is thriving in times of adversity\nThe pandemic has significantly impacted radiology training across Canada. During these unprecedented times, the CAR Resident and Fellow Section has taken every new challenge as an opportunity. From a transition to virtual education, to changes in the usual workflow, our residents, fellows, and medical students have demonstrated exceptional resilience.\nKey Takeaways: Connecting with over 150 CAR Resident Members:Virtual meetings were held with Canadian radiology residents to encourage engagement in RFS activities. Radiology Learners and COVID-19:Now and After: A guide was created with the Canadian Heads of Academic Radiology (CHAR) to identify the changes in radiology training due to COVID-19 and propose actions to augment learners’ education. CARJ Mentorship Program:Residents were paired with the CAR Journal Editorial Board members to peer review scientific articles. Global Outreach in Radiology Network:The first of its kind in Canada, this network was created to help narrow the gap in access to medical imaging. Women in Radiology Mentorship Session:100 participants attended our virtual panel on August 26, in collaboration with the Canadian Radiology Women (CRW). RAD Academy Trainee Section:Resources for trainees were grouped to facilitate learning, including the Royal College Examination Outline for radiology. Canadian Fellowship Database:All fellowship information was updated and uploaded into an online database on the CAR member portal. Additional takeaways from our recent RFS Medical Student Network’s (MSN) activities include: Online Elective Mentorship Program:To bridge the difficulty of this year’s CaRMS applications, in the absence of away-electives, we collaborated with Program Directors and radiology residents to organize 16 virtual information sessions to help medical students learn about each radiology program. Over 300 medical students registered to participate in this initiative from October 11-24. Online Multidisciplinary Radiology Course:590 medical students registered to attend our weekly live radiology teaching sessions. This activity took place from September 19 – October 17 in collaboration with the Academy of Online Radiology Education (ACORE) and medical student ambassadors. Medical Student Radiology Interest Groups:All radiology group leaders joined the MSN. A baseline assessment of their interest groups was performed.\nIn light of these accomplishments, I would like to thank our dedicated team for continuously finding innovative ways to stay engaged with radiology residents, fellows, and medical students. The future of the RFS is promising as we work towards developing new mentorship and wellness opportunities.\nDr. Aline D. Khatchikian CAR RFS Chair, On behalf of the RFS Executive Committee, Resident Representatives, and Volunteers", "pred_label": "__label__POS", "pred_score_pos": 0.7151356935501099}
{"content": "Kind support and encouragement to help you build resilience to meet life's fierce challenges. Counseling for individuals, couples and groups\nYour current life is shaped by what has happened to you, along with your thoughts and beliefs. Uncover what’s subconsciously directing your actions so you can have more health, hope and happiness.\nMindful, body-centered psychotherapy can be an excellent opportunity to explore the obstacles to experiencing a rich, full life. Learn gentle, practical tools for managing emotions. When therapy is used well, you’ll be able to make better choices and move toward being more of who you really are, in accord with your aims and goals.\nSessions are $150 for 60 minutes, payable at the time of your session.\nINSURANCE Reimbursement may be available from your medical savings account, health savings account or insurance, depending upon your policy. Meditation Classes\nMindfulness awareness (shamatha vipashyana) meditation is a simple and profound meditation technique, where we learn to be with our self, as we are. It’s as old as the Buddha, and I’m authorized through this organization to teach meditation. The benefits include stability, strength and clarity of mind. It’s not surprising that research proves the positive effects on our health.", "pred_label": "__label__POS", "pred_score_pos": 0.5482805967330933}
{"content": "Abstract\nBackground: Posterior keratoconus is a rare cause of a corneal opacity in an infant. It is characterized by thinning of the posterior cornea without ectasia of the anterior cornea. Imaging of this condition with anterior segment optical coherence tomography (AS-OCT) has not been reported in the literature. Case presentation: A six week old African-American male presented with a congenital corneal opacity of the right eye. He underwent an examination under anesthesia in which photography and AS-OCT were performed. AS-OCT confirmed the diagnosis of posterior keratoconus. The patient subsequently underwent an optical iridectomy for visual development. Conclusion: AS-OCT is a useful tool in cases when a child presents with a corneal opacity of unknown or unclear etiology. In our patient, AS-OCT showed the classic description of central corneal thinning seen in this condition. Additionally, it revealed an associated detached Descemet membrane, a feature which has not been previously described in posterior keratoconus.\nKeywords Anterior segment optical coherence tomography Corneal opacity Infant Posterior keratoconus ASJC Scopus subject areas Ophthalmology", "pred_label": "__label__POS", "pred_score_pos": 0.7265514135360718}
{"content": "On the morning of October 18, astronauts Christina Koch and Jessica Meir made history by participating in NASA’s first all-female spacewalk. They represent the 14th and 15th women ever to spacewalk since Svetlana Savitskaya in 1984, and they were part of NASA’s 2013 class of eight astronaut trainees — the first to include equal numbers of men and women.\nDuring their eight-hour spacewalk, they successfully made urgent repairs to a failed battery component on the station’s exterior, which was responsible for storing solar power.\nWhile the astronauts received outpourings of praise from the public, Meir emphasized the importance of recognizing the greater historical significance of their mission. \"For us, this is really just us doing our jobs,\" she said. \"We were the crew that was tasked with this assignment. At the same time, we do recognize that it is a historic achievement, and we do of course want to give credit to all of those that came before us.\" Meir also added that she hoped they could be an inspiration to everyone, not just to women.\nAnticipation was high after NASA scratched it’s all female lineup for a spacewalk in March due to a lack of appropriately sized space suits. This sparked a public outcry, highlighting the legacy of sexism in the space program and underscoring the challenges faced by women in historically male-dominated fields.\nThe first spacesuits were originally designed with men in mind. In the 1960s, the International Latex Corporation began making custom spacesuits for each astronaut. This expensive and time consuming process shifted in the 1970s when the company began manufacturing five standard sizes of leg, arm, and torso pieces, which could be interchanged to accommodate varying body sizes.\nHowever, this approach didn’t account for differences in the body shape of men and women, which served as one of the many barriers faced by women admitted to the astronaut program in 1978, and it's still an issue that continues to persist today.\nToday’s astronauts wear space suits designed decades ago, even though they were only intended to last 15 years. The high expenses associated with designing and developing new technology are the basis of NASA’s current spacesuit shortage. Pablo de Leon, director of the Spacesuit Laboratory at the University of North Dakota, estimated that building a spacesuit from scratch could cost as much as $250 million and involve 5,000 man-hours of work. Meanwhile, the limitations of their spacesuits continue to be a source of embarrassment for NASA.\nHowever, after 2 years of design work by a team in Houston, a prototype for a new spacesuit for the 2024 Artemis mission has been recently unveiled. NASA administrator Jim Bridenstine says that the new spacesuit, featuring modular components across the chest and waist that can be adjusted, allows the spacesuit to fit all body sizes “from the first percentile of women to the 99th percentile of men.”\nThis achievement not only represents a critical new technological development, but showcases NASA’s greater effort to remove barriers that historically excluded women and minority groups. Curt Niebur, NASA's program scientist for New Frontiers in Washington D.C., highlights that NASA is working towards increasing diversity in its programs. He says, \"The research now shows the best teams are those that take advantage of the diverse skills, knowledge, and viewpoints that are available.”\nHowever, despite this push for greater representation in space programs, women over the past 15 years have made up just 15% of planetary mission science teams, while only making up about 25% of planetary scientists. In addition, Black and Hispanic people make up just 1% of the nation's planetary scientists.\nThis diversity problem is not unique to the field of planetary science. In many scientific disciplines, even those with substantial female representation—such as biology—there is still a disproportionate number of men in leadership roles. Although the industry is slowly shifting, this imbalance in representation continues to enforce a male-dominated STEM field.\nAccording to a 2013 report by the U.S. Census Bureau, while women represent nearly half of the American workforce, they constitute only 26% of STEM workers. Similarly, Black and Hispanic people account for 6% and 7% of professionals employed in STEM careers, respectively.\nThis disparity can largely be traced to factors such as a lack of role models and educational support for women and minorities in STEM fields. According to a report by UNESCO, “Cracking the code: Girls’ and women’s education in STEM,” women accounted for just 35% of STEM students at institutions of higher education globally.\nAs society progressively moves toward a more inclusive workforce, it is important to highlight efforts to eliminate barriers that historically excluded women and racial minorities while also holding institutions accountable for rectifying historic racism and sexism embedded within STEM fields.", "pred_label": "__label__POS", "pred_score_pos": 0.6543550491333008}
{"content": "A great injury prevention movement is the glute-ham raise. Done after a warm up and prior to competition it will significantly reduce the odds of hamstring strains in running athletes in sports like Soccer, Football and Sprinting.\nTo perform the movement:\nBegin in a tall kneeling position on a cushion or pillow.\nPartner grabs and holds ankles to ground or hook your feet under a stable surface.\nKeeping your torso neutral and your thighs in line with your body, bend forward at the knees, using your hamstrings to control the speed of your forward bend.\nGo as far as you can without cramping, pain or falling to the ground.", "pred_label": "__label__POS", "pred_score_pos": 0.7264294624328613}
{"content": "People have the idea that sleeping properly is responsible for conserving energy; however, studies have revealed that individuals are responsible for burning calories when they are sleeping. Sleep is extremely puzzling and there are several mysteries associated with sleep. Studies have also revealed that sleep helps in improving memory and the emotional stability of individuals. However, one question that lingers is whether these improvements can happen when a person is awake as well?\nWhy do individuals dream?\nThis is one mystery that bothers people from different parts of the globe. Dreaming has fascinated both philosophers as well as scientists for several millennia, and it has been baffling individuals even today. It was considered that dreaming occurs primarily during rapid eye movement sleep. However, you need to know that dreaming can occur during several other stages as well. These dreams are almost like snapshots and are often associated with extremely strong emotions. However, one question is the mystery behind dreams.\nDreaming is responsible for helping with the memory processing function that goes on during sleeping. In sleeping rats, the brains were responsible for activating the neurons, which were used during the day for learning a maze. The activity was almost like they were reliving or practicing that maze. It is believed that similar things happen within the human brain as well. This means that when your sleep involves REM sleep, it can work positively on your ability to solve problems.\nLate nights: good or bad for your health\nAccording to https://time.com, you need to wake up at a similar time every day. Another mystery that is constantly revolving around sleep is why some people can bounce out of bed as soon as the alarm goes on, whereas, few others keep hitting the snooze button constantly. This question is being worked on by Dr. Sam Jones, who is a researcher at the University of Exeter. After investigating the behavior as well as the genetics of almost seven hundred thousand people, his team discovered that almost 300 genes are responsible for playing a role, which involves making you an evening or a morning person.\nThe genetics are not responsible for determining the chronotype but the lifestyle, your habits, diet, and the stimulation that you receive in the evening is responsible for determining your sleep. People, who sleep late at night, tend to experience jet lag and this can lead to depression. Therefore, it is better to sleep at a proper time to ensure good health.\nSome people require less sleep: why\nCertain people do not require a lot of sleep. It has been observed that people who carry a particular gene, is responsible for sleeping less. These people are naturally short sleepers and they do not face any health problems. However, they might find it difficult to carry on their regular day-to-day activities. This is why it is suggested to sleep for 8 hours. The mysteries of sleep are amazing.\nConclusion\nSleep is a mystery in itself. Several mysteries are revolving around sleep. Make sure that you are going through everything that has been mentioned above to understand the several mysteries associated with sleep.", "pred_label": "__label__POS", "pred_score_pos": 0.50154709815979}
{"content": "Protecting What You’ve Worked Hard to Achieve.\nYour success, and what comes with it, should be\nprotected. Personal accomplishment and success are key factors that drive many of us.\nIf attained, they provide security and lifestyles that enable the pursuit of personal interests and passions. For many, personal passions align to charitable works, recreational travel and sport. Others may prefer to study and collect wine, art or other fine articles, creating comfortable environments for their daily lives.\nAt PointeNorth Insurance Group, we want to support the pursuit of your passions with property and casualty risk assessments and planning solutions. You have been diligent in attaining your success, and we want to assist you with protecting the success and lifestyle you have achieved.", "pred_label": "__label__POS", "pred_score_pos": 0.9630925059318542}
{"content": "Polaris tracked the potential impact of the COVID-19 pandemic on victims and survivors of sex and labor trafficking. As part of this effort, Polaris has undertaken a systematic examination of relevant data from the Polaris-operated U.S. National Human Trafficking Hotline. The data brief includes the findings of this analysis and policy recommendations.", "pred_label": "__label__POS", "pred_score_pos": 0.9773252010345459}
{"content": "Thus far, achieving net biodiversity gains through major urban developments has been neither common nor straightforward - despite the presence of incentives, regulatory contexts, and ubiquitous practical guidance tools. A diverse set of obstructions, occurring within different spatial, temporal and actor hierarchies, are experienced by practitioners and render the realisation of maximised biodiversity, a rarity. This research aims to illuminate why this is so, and what needs to be changed to rectify the situation. To determine meaningful findings and conclusions, capable of assisting applied contexts and accommodating a diverse range of influences, a ‘systems approach’ was adopted. This approach led to the use of a multi-strategy research methodology, to identify the key obstructions and solutions to protecting and enhancing biodiversity - incorporating the following methods: action research, a questionnaire to local government ecologists, interviews and personal communications with leading players, and literature reviews. Nevertheless, ‘case studies’ are the predominant research method, the focus being a ‘nested’ case study looking at strategic issues of the largest regeneration area in Europe ‘the Thames Gateway’, and the largest individual mixeduse mega-development in the UK (at the time of planning consent) ‘Eastern Quarry 2’ - set within the Gateway. A further key case study, focussing on the Central Riverside development in Sheffield, identifies the merits of competition and partnership. The nested cases, theories and findings show that the strategic scale - generally relating to governance and prioritisation - impacts heavily upon individual development sites. It also enables the identification of various processes, mechanisms and issues at play on the individual development sites, which primarily relate to project management, planning processes, skills and transdisciplinary working, innovative urban biodiversity design capabilities, incentives, organisational cultures, and socio-ecological resilience. From these findings a way forward is mapped, spanning aspects from strategic governance to detailed project management.\nDate of Award 31 May 2012 Original language English Supervisor Peter D Hedges (Supervisor) urban nature mega-development socio-ecological resilience governance project management", "pred_label": "__label__POS", "pred_score_pos": 0.9142957925796509}
{"content": "Specific phobia is characterized by an excessive fear of an object or a situation which, when avoided, significantly impairs one’s life in some way.\nEmily has always had a fear of vomiting. Although she has only vomited a couple of times in her life, she becomes very anxious if she feels remotely nauseous. She has started to avoid certain foods in case they do not agree with her. She is nervous at public events where people are eating and drinking. Up until recently her fear has not significantly interfered with her life. Now she would like to start a family, but she doesn’t know how she will handle morning sickness.", "pred_label": "__label__POS", "pred_score_pos": 0.7946277260780334}
{"content": "Date: October 31, 2019 Time: 1:00 PM - 2:30 PM ET Organized By: Organizer Webinar Materials Summary: On October 31, 2019, the U.S. Food and Drug Administration (FDA) will host a webinar for device manufacturers and industry to discuss and answer questions about the Special 510(k) Program Final Guidance. Background: On September 12, 2019, the FDA issued a final guidance document on the Special 510(k) Program.\n\"The New 510(k) Paradigm: Alternate Approaches to Demonstrating Substantial Equivalence in Premarket Notifications\" guidance is superseded by this final guidance document and The Abbreviated 510(k) Program, which reflects the Abbreviated 510(k) information from the New 510(k) Paradigm guidance.\nThe FDA also updated the following final guidance documents to reflect the updated Special 510(k) Program, improve alignment between the related 510(k) guidance, and reflect current policies:\nTogether, these guidance documents provide consistency, clarity and transparency to industry and the FDA and may conserve resources for both, while still protecting public health, and not altering the statutory criteria for substantial equivalence.", "pred_label": "__label__POS", "pred_score_pos": 0.9709964990615845}
{"content": "A Geotechnical Engineering Model (GEM) attempts to quantify the impact of thousands, or even millions, of years of four-dimensional geological processes on soil behaviour. Developing a reliable GEM is not a simple matter; it involves integration of geomorphological, geological, geophysical and geotechnical data sets, and a clear understanding of the proposed geotechnical engineering purposes. This paper discusses methods of optimising GEMs, with special reference to soil conditions offshore India.\nPresented at the First India Symposium on Offshore Geotechnics (ISOG 2019)", "pred_label": "__label__POS", "pred_score_pos": 0.9607475399971008}
{"content": "I heard that Lakehead Orillia is phasing out the sale of bottled water on campus. Is this true?\nYes. In December, 2018, the Executive Team Working Group approved the Bottled Water Policy on the Orillia campus and improve access to free, clean, safe drinking water. This phase out will come into effect on January 10, 2019.\nWhy is Lakehead Orillia phasing out the sale of bottled water on campus?\nThe UN Committee on Economic, Social and Cultural Rights states that: \"the human right to water is indispensable for leading a life in human dignity. It is a prerequisite for the realization of other human rights.\" (Source: un.org). As a leader in social responsibility and sustainability, Lakehead Orillia has enhanced free public access to drinking water, and the phase out will also help us reduce the waste associated with thousands of bottled water.\nBut aren't bottled water recyclable?\nWhile bottled water are recyclable, they still require a significant amount of energy to manufacture, transport and eventually recycle. The use of durable water bottles is preferable in energy usage to recycling. Additionally, many bottles that should be recycled instead end up in the landfills, or worse, as litter that pollutes natural areas and watersheds.\nHave other universities and institutions phased out the sale of bottled water?\nYes. Several Canadian universities and colleges have banned and/or encourage the elimination of bottled water.\nWhere on campus can I access free, safe drinking water?\nThere are two water refill stations and approximately eight public water fountains, located at University Avenue and Heritage Place. Refill stations and water fountains are cleaned daily. We will also be installing a water refill station in the Cafeteria.\nWhat about access to water for people with disabilities?\nAll refill stations and public water fountains are accessible.\nIs our tap water safe to drink?\nYes. Canadian municipalities are required to test drinking water multiple times a day. In fact, the quality control of municipal drinking water is much more rigorous than the testing for bottled water.\nWhere can I get a reusable container?\nReusable bottles are available for purchase from the Bookstore. They will be offering 15% off the purchase of reusable water bottles from January 10 to 18, 2019.\nBy inhibiting the sale of bottled water aren't you unfairly targeting bottled water and restricting individual choice?\nOther beverages sold in bottles have similar environmental impacts as bottled water. However, those other beverages are not available from a tap or for free. By promoting tap water, we all help to expose the environmental, health, and socioeconomic impacts of bottled water. The choice in supporting public water and consuming tap water becomes clear.\nCan I bring my own bottled water to campus?\nYes. However, you are encouraged to bring a reusable bottle and take advantage of the refill stations and public fountains available on campus.", "pred_label": "__label__POS", "pred_score_pos": 0.6446107625961304}
{"content": "People often struggle with the same big problems over and over again. Even though the flare-ups are repetitive and predictable, we often don't get any better at handling them. This recording talks about how people can get on a proactive learning track about any big issue. The faster we learn in life, the less victimized we feel by the problem, and the more confident and sensible we become in how we handle things.", "pred_label": "__label__POS", "pred_score_pos": 0.8798605799674988}
{"content": "We invest in public and private corporate credit instruments across multiple strategies.\nGSO's team has a deep reservoir of credit and industry expertise across the entire range of market cycles. Our senior investment professionals have an average of 21 years of industry experience.\nScale allows us to provide financing solutions that enhance a corporation’s financial flexibility, while capturing opportunities our investors might have otherwise missed. Our capital has enabled strong companies to expand and troubled companies to remain viable.\nThe solutions we offer are not often available elsewhere in the credit markets. Their breadth is our competitive advantage – drawing upon a wide range of disciplines, including loans, high yield and investment grade bonds, structured credit, mezzanine lending and rescue financing.", "pred_label": "__label__POS", "pred_score_pos": 0.9898888468742371}
{"content": "Earlier this week, Elizabeth Gargill went one-on-one with Outsourcing-Pharma, discussing findings from BBK's recent Study Voices survey that reveal shifts in healthcare consumer attitudes and behaviors since the onset of COVID-19. nnovation is more important now than ever before and how clinical trial sponsors can leverage the survey findings to enhance their enrollment and engagement efforts.\nThe survey, featuring responses from just over 1,200 patients, medical professionals, and members of the pharmaceutical industry, reveals insights into:\nTelehealth adoption and long-term interest Tools and technologies that impact clinical trial decision-making Shifts in clinical trial interest and awareness\n- Elizabeth Gargill, Market Development", "pred_label": "__label__POS", "pred_score_pos": 0.5527851581573486}
{"content": "CHF 26.00\nBeschreibung des Verlags\nLiberals worldwide invoke Scandinavia as a promised land of equality, while most conservatives fear it as a hotbed of liberty-threatening socialism. But the left and right can usually agree on one thing: that the Nordic system is impossible to replicate elsewhere. The US and UK are too big, or too individualistic, or too - something.\nIn Viking Economics - perhaps the most fun economics audiobook you've ever listened to - George Lakey dispels these myths. He explores the inner-workings of the Nordic economies that boast the world's happiest, most productive workers, and explains how, if we can enact some of the changes the Scandinavians fought for, surprisingly recently, we too can embrace equality in our economic policy.", "pred_label": "__label__POS", "pred_score_pos": 0.7544559240341187}
{"content": "(21 Oct 2020) The COVID-19 pandemic has accelerated the already steady transition towards Open Access publishing. However, precisely what this future looks like and how it will be paid for by smaller, independent publishers is less clear. In this post, Danielle Padula outlines key findings from a report into the current state of Open Access among scholarly society and universities publishing independently. The post details the current state of Open Access publishing and what funding options are currently being explored by publishers.\nLSE Impact of Social Sciences blog has the full article.", "pred_label": "__label__POS", "pred_score_pos": 0.9370823502540588}
{"content": "“Consumers are now digital resources that are mined without being paid for.”\nThe current tax system is no longer adequate because it is not designed for digital business models like Airbnb, Uber, or Amazon. This gives rise to international tax debates, which sometimes raise the question whether we should fall back on ‘old-fashioned’ tax systems. Digital technology, the virtual presence, is new. However, the fundamental cornerstone of taxation - where profits are realized - is not. Even in the Dutch colonial era, a pertinent question was which part of the profits of multinationals could be attributed to the Dutch East Indies and taxed there. Fred van Horzen, partner at KPMG Meijburg & Co, explains.", "pred_label": "__label__POS", "pred_score_pos": 0.9968875646591187}
{"content": "Suicide survivors are most often left with a lifetime quest seeking answers to WHY their loved ones die by suicide. How a suicide survivor processes the death and searches for the reasons “why” will greatly determine their ability to accept the death and continue living healthy lives. Therefore, it is critical for therapists to recognize and take into consideration the unique issues related to a death by suicide. Proven techniques and theories are available.", "pred_label": "__label__POS", "pred_score_pos": 0.8548383116722107}
{"content": "Sustainable Finance\nBeyond green\nOctober 16, 2020Beyond green\nScotiabank hosted its first full-day conference on ESG in Mexico City on June 5, 2020, coinciding with World Environment Day. The purpose of the conference was threefold:\n1. To understand global trends in governance, activism, and ESG from the viewpoint of Morrow Sodali, and learn more about the alignment between Alsea (TP MXN 56.00, Sector Outperform, covered by Rodrigo Echagaray) and Cartica, a global activist in emerging markets;\n2. To provide an overview of the ESG “ecosystem\" – that is, how credit agencies, the buy side, and the sell side include ESG in their analysis, and the data challenges involved; and\n3. To explore how Mexico-based issuers view ESG. Valora, a global consultancy firm, provided insights and valuable content for our panels.\nFrancisco Suarez\nDirector, Global Equity Research, Scotiabank Mexico\n52-55-9179-5209", "pred_label": "__label__POS", "pred_score_pos": 0.9888701438903809}
{"content": "While I appreciate contemporary praise and worship music, I must admit my affinity for the accumulative narrative of hymns.\nEach stanza seems to build upon the preceding verse. I like to think of these classic standards as poetry with a melody. In times like today, the majestic nature of God as expressed in “How Great Thou Art” resonates hope, peace and trust.\nOh Lord, my God, when I in awesome wonder\nConsider all the worlds Thy hands have made\nI see the stars, I hear the rolling thunder\nThy power throughout the universe displayed.\nAs we continue to recover from an exhausting election cycle and grapple with the ongoing COVID-19 crisis, this upcoming holy day season of Thanksgiving is the perfect opportunity to reflect upon and bless God for His keeping power!\nRespectfully, I would hope you do not equate the occasion as “turkey day” or justification for gluttony, as the focus should be upon God who has sustained us in 2020 through adversities seen and unseen.\nWhen through the woods, and forest glades I wander\nAnd hear the birds sing sweetly in the trees\nWhen I look down from lofty mountain grandeur\nAnd see the brook, and feel the gentle breeze.\nMy wife cherishes a collection of several ceramic serving bowls and a small cooking pot. These items do not match the décor of our kitchen or formal dining area. In fact, they don’t even complement each other in appearance.\nYet, they are an integral part of our gatherings.\nThese items once belonged to her beloved mother. I have personally witnessed her mother’s loving ability to prepare and host a banquet. While my wife has embraced and captured her mother’s culinary abilities, the bowls and pots she uses don’t just serve amazing dishes, they beatify memories of others no longer at the table with us.\nAnd when I think that God, His Son not sparing\nSent Him to die, I scarce can take it in\nThat on the cross, my burden gladly bearing\nHe bled and died to take away my sin.\nIt is my hope you will consider small intimate and meaningful gatherings that are limited to your immediate household. Distance traveling is also not recommended at this time due to the escalating widespread surge of coronavirus cases. Consider using technology, such as Zoom, to establish a connection with family and friends.\nAt the end of the day, we are all being reminded, what really should mean the most is that our loved ones are safe, you have done your best humanly possible and you are grateful for what you have.\nWhen Christ shall come with shout of acclamation\nAnd take me home, what joy shall fill my heart\nThen I shall bow in humble adoration\nAnd then proclaim, \"My God, how great Thou art!\"\nWhile nothing is new under the sun, there are some things new to you and me. The word “pandemic” was not a regular part of my vocabulary until this year. In these unprecedented times, many await in angst for the next proverbial shoe to drop! We cannot live and be healthy with such a dire view.\nWhile feasting is often associated with Thanksgiving, we should also commit to fasting as well. Instead of listening to the “breaking news” which only breaks our spirit, let’s turn off the media! The sacred text reminds us that some things will only depart by the means of fasting and prayer. We need a season where we come together, pray and fast and hope that God delivers us as a nation. As the chorus declares:\nThen sings my soul, my Savior God to Thee\nHow great Thou art, how great Thou art\nThen sings my soul, my Savior God to Thee\nHow great Thou art, how great Thou art! A Community Holy Day Gathering: The Mahoning Valley Association of Churches Board invites the community to the Mayors' Interfaith Virtual Prayer on Tuesday from 7:30-8 a.m. To accept this invitation, respond by email to execdirectormvac@gmail.com with a request for the Zoom link. Virtual seats are limited and participants are welcome at no charge.\nThirty-five years ago, the late Mrs. Edna D. Pincham introduced this community mainstay while serving as the administrative assistant to the late honorable Mayor Patrick J. Ungaro. A great woman of faith and prayer, Mrs. Pincham shared her passion with MVAC to host an annual interfaith prayer breakfast. She recognized that the shared tenants of faith brought diversity and strength to our community for the greater good.\nShe envisioned the mayors, their administrations, business, civic and faith leaders of the valley coming together for ecumenical celebration and giving thanks to God.\nThe Zoom gathering affords an opportunity for local political officials and other people of faith to gather and pray together before Thanksgiving in lieu of the Mayors' Prayer Breakfast canceled due to COVID precautions.\nThe Mayors' Interfaith Virtual Prayer will feature a reflection by the honorable Mayor Doug Franklin of Warren; musical performance by Jason Volovar; and interfaith prayers from within the community. Dr. Thomas D. Sauline serves as the executive of MVAC and The Rev. Theodore A. Brown, Jr. is the organization’s president.\nMay this Thanksgiving remind each of us of this holy day’s purpose when it was established in our country. Local philanthropist, Eleanor Watankunakorn, once shared a profound thought she acquired and attributed to her personal journey that required detours along the way, \"Keep your heart free from hate and your mind free from worry. Live simple, expect little and give much”\nLet’s approach this upcoming national observance of thanks with grateful hearts and continue to resolve to keep the faith!\n— The Rev. Lewis W. Macklin II serves as the lead pastor of Holy Trinity Missionary Baptist Church, chaplain for the Youngstown Police Department and local coordinator for the African American Male Wellness Walk of the Mahoning Valley. He resides in Youngstown with Dorothy, his partner in marriage and ministry. They share the love and joy of six children and seven grandchildren. — All biblical citations are New Living Translation unless noted otherwise", "pred_label": "__label__POS", "pred_score_pos": 0.8279595375061035}
{"content": "Abstract\nBackground: The basis of poor outcomes following total knee arthroplasty (TKA) is multifactorial. Previous research aimed at predicting outcome following TKA focuses largely on outcomes measured between two specific time points (pre-to post-TKA). Analysis of outcomes measured over multiple time points (trajectory) may expose relationships between patients’ characteristics and longitudinal outcome patterns that may otherwise remain obscured. Methods: The current study analyzed Short Form 36 Physical Component Score (PCS) trajectories of 656 patients composed of 3 time points over a 1-year period. Clusters were constructed utilizing MultiExperiment Viewer hierarchical clustering algorithm. Statistical significance of these clusters was assessed using MeV's built-in bootstrapping method. Patient characteristics of the resulting statistically conserved clusters were summarized and compared using Wilcoxon rank-sum test or chi-squared test as appropriate. Results: Two distinct clusters of outcome trajectory were identified. Cluster 1 included 550 patients (84%) who demonstrated persistent PCS improvement at 6 and 12 months. Cluster 2 included 106 patients (16%) who demonstrated decline in PCS at 6 months followed by improvement at 12 months. Cluster 1 achieved earlier success, greater absolute mental and physical health scores as compared to Cluster 2 (P < .05), and demonstrated higher baseline mental health scores, lower baseline PCS, and a significantly higher proportion of non-Hispanic Whites (P ≤ .05). Conclusion: Cluster analysis identified distinct functional outcome trajectories following TKA. Specific differentiating patient factors were associated with differing trajectories. Future studies should focus on this method's ability to inform predictive models regarding patient outcomes.\nKeywords functional outcomes outcome trajectory patient-reported outcomes statistical methods total knee arthroplasty ASJC Scopus subject areas Orthopedics and Sports Medicine", "pred_label": "__label__POS", "pred_score_pos": 0.8637819290161133}
{"content": "College can be a challenge for all students, financially and emotionally, but this is especially true for students recovering from cancer. Many students battling cancer may feel that there is no point in carrying on with their education, and the crippling costs of college tuition only exacerbates this.\nWhat we can see is that pursuing a personal goal has a profound impact on a patient’s emotional and psychological recovery. To overcome the financial concerns, there are a wide range of...", "pred_label": "__label__POS", "pred_score_pos": 0.9922276735305786}
{"content": "For those deeply involved in any religion, belief is an essential part of their life. They may never receive a direct communication with the deity of their religion, and the witnessing of a miracle is generally unlikely. While religion has many pragmatic sides, it still takes a leap of faith to be a practicing member of many of today’s faiths throughout the world. Even those who join only for appearances might find they are ready to at least concede the existence of an unseen power.\nIt can be troubling for those who only follow their religion on the surface, and they might never have an epiphany that leads them into true belief. They might find they are wandering away from their own religious background because they are unable to believe without some concrete vision or feeling. For them, it can be less a matter of faith in a powerful being than it is in the comforts of religious rituals that keep them in attendance.", "pred_label": "__label__POS", "pred_score_pos": 0.5401346683502197}
{"content": "Globalization is alluded to as a lot of significant material changes that affect relations between social orders in the previous scarcely any decades. The recognizable highlights of these material changes are seen in the turn of events and development of web, satellite transmission, fiber-optic innovation, broadband activities, transnational partnerships and the rise of World Trade Organization. Globalization is change of how thoughts travel and the idea of their last goal prompting increment in worldwide exchange in this manner expanded rivalry. Firms grow by entering set up business sectors to make new markets for their items. This requires them to have personality for them by setting up trademarks by method of marking and continue overseeing to make esteem.\nWhile growing and infiltrating more current markets creating, advancing and performing advertising tasks utilizing diverse exchange marks for various nations become costlier. The more the nations a trademark is known, the more noteworthy is its worth and the more noteworthy the need to ensure the equivalent by enrolling at the worldwide level. Trademark enrollment includes greater expenses as well as procedural requirements while enlisting the equivalent in each nation and check about\ndang ky thuong hieu. Brands have become some portion of a monetary market, yet in addition an allegorical market since they include and engender an arrangement of utilizing signs to control significance and language as brands satisfies a few distinctive financial capacities. Recognizable proof on an essential level, it serves an ID work by partner an item with an organization.\nCorrespondence More dynamically, it has a useful capacity, in that it gives a vehicle to the effective correspondence of data, along these lines lessening purchaser search costs in picking an item. Flagging the utilization of marking in promoting additionally serves a flagging capacity, in that, it proposes that an organization who is eager to exhaust a significant entirety on its publicizing more likely than not built up a decent item. Articulation lastly, marking likewise serves an expressive capacity, as in it interfaces a specific buyer character or pith with an item. Marking includes not simply the item name, ads, or the utilization of a logo, yet the center suppositions and convictions that are evoked when one thinks about the brand. The best brands were the individuals who could create a specific mental inclination about the item. In this way, the brand pith moved away from an attention on the item and toward a mental relationship of the brand with a specific character. Today, firms embrace umber marking system, in which firms dedicate a significant segment of their salary towards putting their logo on a wide range of items and occasions, further enhancing the connection between mental, social and corporate affiliation.", "pred_label": "__label__POS", "pred_score_pos": 0.8898627161979675}
{"content": "Driving While Intoxicated (DWI) is a serious crime that may carry lifelong repercussions. If you have been charged with a DWI in Stanislaus County California it is strongly recommended that you find a criminal defense attorney who is experienced with DWI law.\nStanislaus County Lawyers Experienced in DWIs\nIn most situations, a DWI in California require a significant amount of evidence and legal experience to competently litigate. Because the state must prove you committed the crime beyond a reasonable doubt, you may have a variety of different avenues of attack against a DWI charge.\nStanislaus County Attorneys Can Help You Avoid Penalties and Fees If You Are Facing a Charge for DWI\nAfter you have been charged with a DWI, your initial step should always be to consult a qualified legal representative. This lawyer can help you decide whether it would be possible to fight the charge, or to negotiate a plea bargain. Stanislaus County, California DWI attorneys will examine your case and use their expertise to explain your options and assist you in making the best legal decisions.\nIt is very important to talk with a DWI attorney as soon as possible; your freedom might depend on it.", "pred_label": "__label__POS", "pred_score_pos": 0.6150409579277039}
{"content": "(From D3 Supervisor Aaron Peskin)\nEarly pain is yielding early gains. San Francisco policymakers confronted COVID-19 head on, and we’re finally reaping the signs of success. While our federal government denied the science, we acted on it. While the President and his administration obscured facts, we pushed for more transparency.\nWe’re not entirely in the clear, but San Francisco has become the first county in California to reach the least restrictive tier (“yellow”) in the state’s recovery blueprint. While some were predicting that our dense urban environment would lead to high rates of transmission, instead we came together and worked for our collective safety. As a result, dense neighborhoods like Chinatown have all but quashed the transmission of COVID-19 thus far.We have demonstrated the strength of our neighborhoods and a societal commitment to mutual aid.\nIn the past few weeks, we’ve safely and successfully allowed limited capacity reopening of indoor dining, gyms and fitness centers, movie theaters, and playgrounds. We’re on track for non-essential offices, indoor personal care, and limited in-person public schools in the coming days and weeks. Fingers are crossed.", "pred_label": "__label__POS", "pred_score_pos": 0.5071104168891907}
{"content": "Terlipressin (Glypressin), a synthetic analog of vasopressin, induces arteriolar vasoconstriction which causes both a portal hypotensive effect and certain side-effects on the systemic circulation (elevated arterial pressure and reduced cardiac output). The combination of nitroglycerin with terlipressin might accentuate the portal hypotensive effect and prevent the side-effects on the systemic circulation. The aim of this study was to examine the systemic and splanchnic hemodynamic responses to terlipressin administered alone or combined with nitroglycerin in patients with cirrhosis. Systemic and splanchnic hemodynamics were measured before and 1 h after a bolus of terlipressin (1 to 2 mg IV) given alone (n = 10) or in association with nitroglycerin infusion (25 micrograms/min, n = 9). Terlipressin alone significantly increased the arterial pressure by 21%, systemic vascular resistance by 60%, and significantly decreased cardiac output by 23%. The right atrial and pulmonary pressures significantly increased and the wedged hepatic venous pressure and hepatic venous pressure gradient significantly decreased by 8% and 16%, respectively. The combined therapy decreased the cardiac output by 20%, but did not significantly modify the other systemic and splanchnic hemodynamic values. No significant differences were found between terlipressin and the combined therapy concerning changes in wedged hepatic venous pressure or hepatic venous pressure gradient. We conclude that in patients with cirrhosis, nitroglycerin prevents the deleterious vasoconstrictor and vasopressor effects of terlipressin. However, the combined therapy, as terlipressin alone, decreases the cardiac output.(ABSTRACT TRUNCATED AT 250 WORDS)", "pred_label": "__label__POS", "pred_score_pos": 0.9845625758171082}
{"content": "Objective: A key mediator of vascular EC barrier integrity, S1P, is derived from phosphorylation of sphingosine by the SK-1 and SK-2. While previous work indicates that SK-1 can regulate EC barrier integrity, whether SK-2 has a similar role remains to be determined. Methods: A cell impedance assay was used to assess human umbilical vein EC and bone marrow EC barrier integrity in vitro, with application of the SK inhibitors ABC294640, PF543, SKi, and MP-A08. In vivo studies were conducted using intravital microscopy to assess EC barrier integrity in SK-1 (Sphk1(-/-)) and SK-2 (Sphk2(-/-)) knock-out mice. Results: Only ABC294640 and MP-A08, which can both inhibit SK-2, caused a decrease in EC barrier integrity in vitro in both cell types. Intravital microscopy revealed that Sphk1(-/-) mice had reduced EC barrier integrity compared to WT mice, whereas no change was evident in Sphk2(-/-) mice. Conclusions: Our data suggest that in vitro inhibition of SK-2, can compromise the integrity of the EC monolayer, while SK-1 exerts a more dominant control in vivo. These data may have clinical implications and could aid in the development of new treatments for disorders of vascular barrier function. Keywords: endothelial cell barrier integrity; sphingosine kinase; sphingosine-1-phosphate.\n© 2016 John Wiley & Sons Ltd.", "pred_label": "__label__POS", "pred_score_pos": 0.9683763980865479}
{"content": "Authors:\nAnn C. Gregory, Olivier Zablocki, Ahmed A. Zayed, Allison Howell, Benjamin Bolduc, Matthew B. Sullivan\nSummary:\nThe gut microbiome profoundly affects human health and disease, and their infecting viruses are likely as important, but often missed because of reference database limitations. Here, we (1) built a human Gut Virome Database (GVD) from 2,697 viral particle or microbial metagenomes from 1,986 individuals representing 16 countries, (2) assess its effectiveness, and (3) report a meta-analysis that reveals age-dependent patterns across healthy Westerners. The GVD contains 33,242 unique viral populations (approximately species-level taxa) and improves average viral detection rates over viral RefSeq and IMG/VR nearly 182-fold and 2.6-fold, respectively. GVD meta-analyses show highly personalized viromes, reveal that inter-study variability from technical artifacts is larger than any “disease” effect at the population level, and document how viral diversity changes from human infancy into senescence. Together, this compact foundational resource, these standardization guidelines, and these meta-analysis findings provide a systematic toolkit to help maximize our understanding of viral roles in health and disease.\nSource: Cell Host & Microbe, 2020", "pred_label": "__label__POS", "pred_score_pos": 0.8001633882522583}
{"content": "Through this project, the BeLongEng team will track the practices and contexts of a cohort (panel) of individual engineers over time, using a prospective longitudinal cohort approach. It is anticipated that this project will provide evidence into how and why engineering practice is changing, leading to a more responsive and productive learning and workplace ecosystem.", "pred_label": "__label__POS", "pred_score_pos": 0.9999619126319885}
{"content": "By Maxine Philavong\nAfter several lawsuits that were backed by large U.S. companies, the Trump administration relaxed part of its so-called “immigration ban” on foreign nationals, permitting those on H-1B and L-1 visas to return to their previous held employment in the U.S..\nIn April, the administration barred all foreign nationals who did not previously hold a valid visa from working in the U.S. for 60 days due to the Covid-19 pandemic. In June, President Trump signed an executive order extending their ban of all workers with a H-1B and L-1 visa, until the end of the year.\nThis meant that if a person had been waiting for these visas to be issued, or if you already had either of these visas but were waiting for it to get stamped, said person would have now had to wait until at least the end of the year.\nThe ban put thousands of foreigners waiting for their visas outside of the U.S. in a tough spot. For new visa holders waiting in their home country and those with a visa who had traveled to their home countries for stamping now found themselves barred from returning to the U.S. until the end of the year. Many feared job loss if they were not permitted to return.\nMoreover, dependents of the visa holders were impacted, too. If a spouse of the visa holder had traveled to their home country to get their visa stamped but could not secure an appointment before the ban, they may have found themselves stuck in their home country.\nHowever, after pushback from lawsuits that were back by large companies like Apple and Microsoft, the Trump administration has relaxed part of the ban.\nWho Qualifies for the H-1B and L-1 Visa Exception?\nAfter relaxing the ban on H-1B and L-1 Visa applications, the Trump administration favors those who qualify for national interest exception. This applies for those who are aiding in the fight against Covid-19 or those whose positions aid in economic recovery in the U.S. Meaning, there special exception for H-1b applications who are “technical specialists, senior level managers, and other workers whose travel is necessary to facilitate the immediate and continued economic recovery of the U.S.”\nAdditionally, for both visa categories, the administration grants exception to those “seeking to resume ongoing employment in the U.S., in the same position, with the same employer and with the same via classification.”\nThose traveling under the H-1B and L-1 visa to the U.S. should be able to prove at least two of the five criteria: “Their employer has a continued need for their work even during the pandemic; they make a significant contribution to a critical infrastructure need; they are paid at least 15% more than the prevailing wage; they have an unusual expertise in the industry; or that their employer would suffer financial hardship if their via was denied.”\nThis article is published for clients, friends and other interested visitors for information purposes only. The contents of the article do not constitute legal advice and do not necessarily reflect the opinions of Davies & Associates or any of its attorneys, staff or clients. External links are not an endorsement of the content.", "pred_label": "__label__POS", "pred_score_pos": 0.7678021192550659}
{"content": "Joy to The World\nThe Bible provides three significant accounts surrounding the birth of our Savior, Jesus Christ.\nLuke 2:8-12 also recounts Elizabeth’s (and her fetus’) joyful expression at the news that her cousin, Mary, carried the coming Messiah. In Luke 1:41-44 Matthew 2:7-10, Bible indicates that at the sight of the star, the wise men, “ rejoiced exceedingly with great joy.” Consistently, Bible emphasizes that Jesus’s birth was characterized by joy.\nJesus’ life and ministry on Earth was also marked by joy.\nThough His purpose was to die a painful and humiliating death, the Bible tells us His life was full of joy. Prior to His crucifixion, in , He prayed for His disciples, “ John 17:13 But now I come to You, and these things I speak in the world, that they may have my joy fulfilled in themselves.” Though His death was imminent and inevitable, the Gospel of Luke states, Jesus was full of joy and the Holy Spirit! You cannot have the Holy Spirit and not have joy for the Holy Spirit produces joy in your life.( ) The joy Jesus possessed was a result of His relationship with the Father. So also, Gal. 5:22 that joy is accessible to us when we strengthen our connection to the Father through the Holy Spirit.\nKay Warren, author of\nChoose Joy, defines joy as, “ the settled assurance that God is in control of every detail of my life, the quiet confidence that ultimately everything will be alright and the determined choice to praise God in all things.” Another defines this, “ Joy is an emotion that resides deep in your soul produced by the Holy Spirit which focuses on Jesus Christ.” If the Holy Spirit produces joy, then it follows that joy is not temporary; it is not transient. Happiness is based on happenings, but joy comes from deep within. Joy is a choice; a daily choice. It emanates as a result of the presence of God – i.e. the Holy Spirit, that dwells in you. Joy is a fruit of the Holy Spirit ( ); Paul also states in Gal. 5:22 that “ Romans 14:17 For the kingdom of God is not a matter of eating and drinking, but of righteousness, peace and joy in the Holy Spirit.” Joy isn’t hinged on our circumstances, but the faithfulness of God, therefore, as Paul states in , 1 Thessalonians 5:16 rejoice always; irrespective of the circumstances.\nThe toils and struggles of life are bound to happen, but we must resolve to remain in joy. We know our adversary comes to steal, kill and destroy (\nhe will try to rob you of your joy. Know this - real joy in Christ cannot be stolen. Paul an apostle who spent most of his ministry being persecuted, lashed and tortured heartens us to rejoice in our sufferings ( John 10:10); 2 Cor. 11:25-28; Phil. 4:4) While the enemy may seek to destroy things in your life, decide to remain in joy. There are many things that drain us of our joy- anxiety, resentment, confusion; we all face difficulties in life. It is easy to let the pressures of life weigh us down and become negative or discouraged. God does not intend for us to live life depressed and dispirited. We were created to enjoy life. . Joy is a powerful tool; seek to maintain joy by abiding in Jesus ( ) To abide is to live in His presence daily. In His presence, there is the fullness of joy. ( John 15:5 Ps. 16:11 )Abiding in Christ allows you to bear the fruit of joy for the world needs joy! When we decided to abandon the world and chose to follow Christ, we chose to live a life of joy. We must endeavor to be couriers of joy because the Holy Spirit who produces life-sustaining joy resides in us. Joy has a voice and must be expressed.( Ps. 9:2; Ps. 32:1; Ps. 68:4) For expressing our joy attracts people to the kingdom of God.\nBegin this year with the determination that 2020 will be your\nyear of joy. Make the decision to be and remain joyful. Spread joy wherever you go. If Paul could do it naked, we can do it clothed. If Paul could remain joyful in prison, we can do it as we live freely in the land of the free. If Paul could do it bruised and tortured, we can do it in spite of our circumstances. “ Rejoice always, again I say rejoice.” Selah.", "pred_label": "__label__POS", "pred_score_pos": 0.5672718286514282}
{"content": "You View the World in 3D. Why Not Document in 3D.\nForensic 3D Laser Scanning\nThis state-of-the-art technology has had a significant impact in the forensic field – not just collision reconstruction, but also for any case that requires precise measurements. 3D scanning allows for the collection of millions of accurate measurements in a cost-effective and efficient manner, with unprecedented accuracy.\nWhen an event or incident occurs that requires investigation, there is nothing more critical than preserving the evidence and the scene. 3D laser scanning is particularly useful in time critical situations, such as vehicle and human-related accidents; homicides and criminal investigations; as well as damage to structures, when the environment needs to remain uncompromised.\nHistorical 3D Laser Scanning\nWith the use of 3D laser scanning technology, computer modeling and panoramic photography, DJS Associates digitally preserves historical sites and landmarks.\nData collected can be utilized for historical preservation, condition assessment, reconstruction of structures, as well as for restoration and cultural education. DJS is also partnering with CyArk, a non-profit organization dedicated to protecting the world’s heritage through cutting-edge technology, for digital preservation and educational purposes.\nArchitectural 3D Laser Scanning\nDetailed measurements and photographic documentation of existing conditions are crucial elements of the design process – from initial conception through final construction. Combined with HDR Panoramic Photography, 3D imaging provides a cost-effective, accurate and efficient means to capture the data necessary for documentation, design and construction.\n3D laser scanning is applicable to numerous situations including as-built documentation for pre-construction and construction; historical preservation and renovation; building information modeling (BIM); and permanent 3D representation of sites, whether digital or printed.", "pred_label": "__label__POS", "pred_score_pos": 0.7444512844085693}
{"content": "Norton Rose Fulbright’s Jeremy Moller highlights the advantages of regulating legal, accounting and real estate services under Australia’s AML laws, sooner rather than later.November 19, 2020\nThe probe is related to Crown's use of casino junkets to bring wealthy gamblers to its Melbourne casinos and possible non-compliance with due diligence and AML requirements.October 21, 2020\nThe roadmap seeks to address key challenges faced in cross-border payments including high costs, low speed, limited access and insufficient transparency.October 13, 2020\nOnboarding processes should be designed reflecting the principle that CDD is not merely a document collection exercise, the HKMA says.September 25, 2020\nIf the Federal Court of Australia determines the penalty is appropriate, it will represent the largest ever civil penalty in Australian history.September 24, 2020\nState Street Bank and Trust failed to report IFTIs on 99 occasions. There is no suggestion that the transactions were suspicious or that there were CDD deficiencies.September 17, 2020\nResponding to a European Commission call for advice, the EBA says it recommends the establishment of a single rulebook to harmonise the AML/CFT framework across the EU.September 11, 2020\nGuidance is provided for financial institutions, DNFBPs and NBFIs on AML/CFT and targeted financial sanctions, customer due diligence and beneficial ownership.September 3, 2020\nThe SFC will remove investment restrictions, expand custodian eligibility requirements, and introduce a statutory re-domiciliation mechanism.September 3, 2020\nThe guidance sets out key practices banks have been using to manage customer due diligence, resource pressure, and emerging threats in the context of Covid-19.July 30, 2020", "pred_label": "__label__POS", "pred_score_pos": 0.9841709136962891}
{"content": "Assumptions often govern our understanding of the world and those around us. We guess what it's like to be rich and famous, or the impact of travelling a long, rocky road due to disability or misfortune.\nMany people start their journey living with a mental illness with little practical knowledge of the long-term effect their symptoms may have. They may not understand the battles they'll need to fight just to leave the house, visit family, go to work, or attend treatment.\nTo understand how the reality of mental illness and how it differs from first impressions, we asked nine SANE Peer Ambassadors to share their experiences.", "pred_label": "__label__POS", "pred_score_pos": 0.9919186234474182}
{"content": "›\nThe Conservatives have lost their absolute majority in the British parliament, further weakening the government’s ability to negotiate the UK’s exit from the European Union › Uncertainty surrounding the outlook for the UK is expected to remain strong and impact activity levels over the coming quarters. In line with our expectations, the pound sterling could fall significantly › Although more confident about the outlook for growth, the ECB has confirmed that monetary tightening is not imminent. The euro’s upside pressures are therefore expected to be limited\nFocus on India: Growth potential still intact (p.5)\n› With 6.1%, GDP growth for the first quarter of 2017 was disappointing and reflects the delayed – and higher-than-expected – impacts of the demonetisation, as well as statistical biases. This slowdown is expected to be temporary › Private consumption has continued to trend up, while the legislative elections at the start of the year reinforce N. Modi’s political legitimacy › Private investment is still the weakest link and needs to be supported by bank lending", "pred_label": "__label__POS", "pred_score_pos": 0.7420623302459717}
{"content": "A calming neurotransmitter\nTaurine is a crystalline, free-form amino acid. It is a soothing, inhibitory neurotransmitter and plays a major role in stabilizing the heartbeat and electrical activity of the nerves.\nTaurine is also necessary for the proper functioning of the \"sodium/potassium ATP-ase pump\" which regulates the ion balance between the cells and the extracellular fluid that surrounds them. Warnings\nIf you are pregnant, may become pregnant, or breastfeeding, consult your health care professional before using this product. Do not use if either tamper-evident seal is broken or missing. Keep out of the reach of children.\nDisclaimer\nThese statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.\nUPC: 021078012818\nTaurine Other Ingredients: Sorbitol, Stearic Acid, Modified Cellulose Gum, Colloidal Silicon Dioxide, Magnesium Stearate\nTake 1 tablet a day, between meals or at bedtime. If you experience stomach irritation, take with meals.", "pred_label": "__label__POS", "pred_score_pos": 0.7039668560028076}
{"content": "Utilise the full potential of new water technologies.\nThe water sector is under increasing pressure from population growth, economic development, climate change and urbanisation. These factors are intensifying water scarcity on a global scale, driving demand for an innovative approach that addresses the inherent energy, cost and performance inefficiencies of existing water and waste water treatment facilities and networks.\nEmerging technologies present utilities, operators, EPCs and investors with a high degree of uncertainty regarding reliability and comparability. In particular, the need for higher efficiencies and overall sustainability has led to the wide deployment of membranes, sensor systems and other novel technologies. However, in the absence of objective comparative evaluation, stakeholders may risk making poor investment decisions.\nTÜV SÜD supports the water sector with performance testing and verification services for key technologies and components such as membranes, sensors and water purifiers. These services can be provided in the lab or in the field. Operators, utilities, investors, end users as well as EPCs and equipment manufacturers can gain confidence in their technologies and investments by having products tested and verified.", "pred_label": "__label__POS", "pred_score_pos": 0.8356420993804932}
{"content": "On May 28, Akinwumi Adesina, Nigeria’s Minister of Agriculture and Rural Development, was elected as the new president of the African Development Bank – the continent’s multilateral development finance institution. Adesina takes the helm from Rwandan economist, Donald Kaberuka, who has served in the post for the maximum period permitted – two five-year terms.\nThe appointment marks the growing influence of Nigeria, not only as Africa’s financial powerhouse, but also in terms of its diplomatic role and political clout in the region\nOnly the eighth person to be appointed to the role, the agricultural economist beat Chad’s former Finance Minister, Kordjé Bedoumra, and Cape Verde’s serving Finance Minister, Cristina Duarte, by 60 percent. Voting was carried out by the AfDB’s board of governors, which comprises 54 regional member states and 26 non-regional members. Voting powers are weighted, with Nigeria, the US and Egypt yielding the most influence in elections.\nSince being established in 1963, the AfDB has held a firm position on electing individuals from smaller African economies so as to offset the balance of power in the region. By electing an individual from Africa’s largest economy, the group has made a clear shift from this norm. Moreover, the appointment marks the growing influence of Nigeria, not only as Africa’s financial powerhouse, but also in terms of its diplomatic role and political clout in the region. Adesina’s presidency will also bring Nigeria’s in closer stead, politically speaking, with the continent’s former largest economy, which still enjoys considerable power in the region, as the African Union is headed by South African Nkosazana Dlamini Zuma.\nAdesina, who has served under outgoing president Goodluck Jonathan, has taken a more commercial approach to agriculture and is credited for boosting rice production in Nigeria. The 50-year-old has also been praised for improving the country’s fertiliser subsidy programme, encouraging the diversification of crops among farmers and cracking down on corruption in the sector.\nAdesina was considered among the favourites during the run-up to the election, winning favour with populist rhetoric during his campaign and speaking of greater inclusion across the continent. With a PhD in agricultural economics, during his campaign, Adesina naturally has focused on the importance of agriculture in Africa’s development and lifting nations out of poverty.\nFollowing the announcement, which was made at the group’s 50th Annual Meeting in Abidjan, Côte d’Ivoire, the group’s new president said that he was “humbled by this remarkable vote of confidence in me”. He also expressed praise to his predecessor; “I salute the excellent work of President Kaberuka. It will be a big challenge for me to step into his shoes. He leaves a solid bank behind him.”\nThe AfDB, which is charged to drive Africa’s economic and social development, has supported growth across the continent over the past decade in a pivotal period in the region’s economic advancement. According to the AfDB’s Annual Report, which was released just days before the group’s presidential election, the continent achieved 3.9 percent GDP growth in 2014, with the number expected to rise to 4.5 percent this year.\nAdesina will assume office on September 1 this year, arguably taking to the helm at the cusp of a breakthrough in Africa’s economic development.", "pred_label": "__label__POS", "pred_score_pos": 0.6205522418022156}
{"content": "Supporting employees during this unprecedented time calls for innovative approaches. As reported by CNBC, some companies are requiring employees to take time off to avoid burnout. The article notes that “… work and personal time can blur into an endless purgatory of screen time and video calls.” and “… people might not want to use vacation days if they feel they can’t do what they used to do.”\nPerhaps you’d like to encourage your team to take vacation time, but in the current situation, employees have fewer options that feel safe for a local “staycation” or regional trip.\nDrift for Teams offers a creative solution with deeply discounted bulk pricing. This makes a float session an economical way to support employees health and well-being with a no-contact, socially-distant spa experience!\nPackages can be customized for your health and wellness initiatives to support your team of professionals, creatives or athletes. Email us for more information.\nDrift for Performance offers a creative solution. The deeply discounted bulk pricing makes a float session and economical way to support employees health and well-being, and the no-contact, socially distant spa experience is great for morale!\n+1-864-414-2388\nprograms@driftgreenville.com", "pred_label": "__label__POS", "pred_score_pos": 0.9893273711204529}
{"content": "A coalition is an organization of diverse interest groups that join their human and material resources to produce a specific change that they are unable to deliver as independent individuals or separate organizations. A coalition is the foundation of your efforts and can help you on several fronts, including a core program need to amass community and leadership support for your hunger-free community program.\nThis document focuses on coalition-building related to stroke and heart disease prevention.", "pred_label": "__label__POS", "pred_score_pos": 0.8580290079116821}
{"content": "Usnea has a specific affinity for the lungs. It assists in respiratory infections and illness acting as a herbal antibiotic.\nUsnea is often referred to as the Herbal Anti-biotic. You may have seen this lichen on the ground or growing on trees during one of your hikes. You probably didn't know that the inconspicuous gray-green fuzzy stuff covering many of the trees is one of the gentlest yet strongest immune tonics in the herb world.\nCommonly known as Old Man's Beard, this highly specialized lichen acts as the lungs of the forest. It is naturally antibacterial, antimicrobial, anti fungal and antispasmodic. It has a special affinity for re balancing bacteria and eradicating infection throughout the mucus membranes, from mouth to lungs to gut to urinary tract and on. This medicine is a special gift for those with signs of infection in the lungs and bronchial area, often indicated by yellow or green phlegm, colds, flus, sinus infections, chest pain, difficulty breathing and sometimes accompanied by a fever.\nIngredients: LOVE, Usnea, and alcohol. To use: Adults take 1 dropper three times a day for a maximum of 7 days.\nPlease consult your doctor if you are nursing or pregnant.\n*The above statements have not been evaluated by the Food and Drug Administration. Please note that this product is a natural herbal supplement meant to support your current regimen for maintaining intrinsic health, and is not meant to be a substitute for medical care. As per FDA regulations, all presented information and products are not meant to treat, diagnose, prevent, or cure any disease. I recommend that you consult with your qualified healthcare practitioner before using herbal products if you have any questions regarding their effect in combination with your unique bodily needs, particularly if you are pregnant, nursing, or on medications.", "pred_label": "__label__POS", "pred_score_pos": 0.8178448677062988}
{"content": "“More than 350 Austinites were seriously injured or killed in the last five years on just these 13 sections,” Austin Transportation Director Robert Spillar said in a press release. \"By using a data-driven approach, we’ve identified locations which would greatly benefit from lower-cost solutions to quickly enhance safety for everyone who travels on our roadways, whether you drive, walk, bike or take transit.”\nInitial improvements for Slaughter Lane between Menchaca Road and I-35 include traffic signal and signage upgrades, including signs that indicate drivers are entering a \"high crash roadway\" in both English and Spanish. Other improvements, such as low-cost street design changes, bus stop relocations, improved lighting and refreshed roadway markings could come later.\nAs efforts to reform the 13 high-injury roadways moves forward, the Austin Transportation Department will reach out to area residents and neighborhood groups for feedback regarding needed efforts to reduce speeding, distracted and impaired driving and failure to yield.\nWhile Slaughter Lane is among the first high-injury roadways to receive Vision Zero improvements, other South Austin arteries will receive updates later on, including South First Street, William Cannon Drive and South Congress Avenue.", "pred_label": "__label__POS", "pred_score_pos": 0.6959975957870483}
{"content": "Experience Yoga\nModule 5 – Lesson 4.1: Retraining unhelpful thinking\nModule 5 – Lesson 4.1:\nRetraining unhelpful thinking Our codes for living soulfully in the world\nWe can use the details of our everyday life as raw material for developing our self-awareness and self-observation. This can assist us to think and feel more impartially, act more wisely and ultimately uncover a calmer mind.\nThe ancient teachings of yoga are conveyed in the Yoga Sutras of Patanjali, a series of short sentences of wisdom. These include the\nyamas and niyamas, which can be considered intuitive guidelines to bring into all dimensions of our daily life. These can also be practised as a mindfulness to raise our awareness.\nThe\nyamas and niyamas assist us to cultivate a deeper understanding of our attitudes and behaviors — the ways we treat ourselves, others, and the world around us. These insights can lead to personal change not only benefiting ourselves, but others in our life!\nThe video below explains the\nyamas and niyamas with some ideas about how to apply these to yourself and in your daily life.\nThis list below includes some\npractical tips, to support you to bring the yamas and niyamas into your daily life:\n1. Goal setting: Honestly evaluate your capacity for change in an area of our life – be specific, but practical.\n2. Consequences: Lovingly, patiently, skillfully win over any inner resistance, so that your mind becomes your ally.\n3. Positive affirmations: State what you wish to develop clearly, succinctly and in the present tense – refer to previous Lesson 3.1 – Affirmations.\n4. Pratipaksha Bhavana: This yogic technique helps you to overcome negative patterns, by consciously inviting you to cultivate the opposite positive thought in your mind. This can help bypass the mind’s resistance to change.\n5. Accountability: Every day, pause, reflect, and notice your progress. A few moments a day helps you to stay on track.", "pred_label": "__label__POS", "pred_score_pos": 0.7641992568969727}
{"content": "The human condition encompasses the unique features of being human. It can be described as the irreducible part of humanity that is inherent and not dependent on factors such as gender, race or class. It includes concerns such as the meaning of life, the search for gratification, the sense of curiosity, the inevitability of isolation, or anxiety regarding the inescapability of death.", "pred_label": "__label__POS", "pred_score_pos": 0.9999970197677612}
{"content": "On March 25, the House Appropriations Committee unanimously passed its FY 2017 Transportation, Housing and Urban Development (T-HUD) spending bill after debate on several housing- and transportation-related amendments, though only a manager’s amendment making technical changes to the bill was ultimately approved. The House bill received a robust $48.2 billion allocation, which is $1.7 billion higher than the Senate allocation, but due to differences in accounting tactics, the Senate bill provides higher funding levels for most housing and community and development programs compared to the House bill. The Senate approved its T-HUD bill on March 19 with an 89-8 vote.\nNAHRO’s policy team has provided a comprehensive summary of the House bill as it relates to HUD’s Community Planning and Development programs, including the Community Development Block Grant (CDBG), HOME Investment Partnerships Program (HOME), Homeless Assistance Grants, and Housing Opportunities for Persons with AIDS (HOPWA). NAHRO will also publish comprehensive coverage of the House bill’s treatment of Public Housing and Section 8 Programs in the coming days.\nAccess NAHRO’s analysis here (members only).", "pred_label": "__label__POS", "pred_score_pos": 0.9034788608551025}
{"content": "The amount of settlement that you receive after an accident predominantly depends on factors surrounding your case. Based on these factors, your personal injury lawyer can manage your expectations and negotiate skillfully and efficiently, with the goal of helping you get rightfully compensated.\nIf you’ve been severely injured in a motor vehicle accident in North Carolina due to the other party’s negligence, then you should do two things:\nMotor vehicle accidents are unfortunately quite common in North Carolina. Did you know that there were nearly 275,067 collisions on the roadways of North Carolina in 2017? This figure was up by approximately 9000 from the figure recorded in 2016, and about 40,000 more than the figures recorded from 2012 to 2016.\nIf you or a loved one has been severely injured in an accident, then you have the right to file a personal injury claim and seek compensation for the injuries and losses. However, the outcome of your case often depends on the way it is pursued. This is why it is advisable to hire a personal injury lawyer. With over 130,000 personal injury attorneys currently working in the US, selecting a lawyer to represent your case is not easy. And this is exactly what we’ll focus on in today’s post. Read on to learn about crucial steps that you can take when choosing a lawyer for legal representation.\nPersonal injuries can occur when least expected. Whether a person sustains a minor or major injury, it can disrupt their life and relationships. Not only that, the expensive medical treatments and medication following an accident can cripple you financially. In such a situation, you may be reluctant to seek professional legal assistance, thinking of it as another expense.", "pred_label": "__label__POS", "pred_score_pos": 0.5296025276184082}
{"content": "Abstract\nHigh-performance liquid chromatography with fluorescence detection has been utilized for the rapid determination of total homocysteine, cysteine, and cysteinylglycine in human serum and plasma. Our earlier procedure (Anal Biochem 1989; 178:208), which used monobromobimane to specifically derivatize thiols, has been extensively modified to allow for rapid processing of samples. As a result, >80 samples a day can be assayed for total homocysteine, cysteine, and cysteinylglycine. The method is sensitive (lower limit of detection ≤4 pmol in the assay) and precise (intra- and interassay CV for homocysteine, 3.31% and 4.85%, respectively). Mean total homocysteine concentrations in plasma and serum were significantly different, both from healthy male donors (9.26 and 12.30 μmol/L, respectively; P <0.001) and healthy female donors (7.85 and 10.34 μmol/L, respectively; P <0.001). The differences in total homocysteine between sexes were also significant (P = 0.002 for both plasma and serum). Similar differences were found for cysteine and cysteinylglycine. We found a significant inverse correlation between serum cobalamin and total homocysteine in men (P = 0.0102) and women (P = 0.0174). Serum folate also inversely correlated with total homocysteine in both sexes.\nOriginal language English (US) Pages (from-to) 873-881 Number of pages 9 Journal Clinical Chemistry Volume 40 Issue number 6 State Published - 1994 Externally published Yes ASJC Scopus subject areas Clinical Biochemistry", "pred_label": "__label__POS", "pred_score_pos": 0.573454737663269}
{"content": "Terms & ConditionsThe Beyond your Belly program is designed for general information only and should not replace advice from a medical professional. We recommend you seek professional advice before embarking on any new health regime.\nThis program uses healthy, natural food, but there are some cases where it may not be appropriate. If any of the following medical conditions apply to you, please do NOT purchase this program until you have sought medical advice:\nCarnitine deficiency (primary), Carnitine palmitoyltran-ferase (CPT) I or II deficiency, Carnitine translocase deficiency, Beta-oxidation defects, Mitochondria3-hydroxy-3-methylglutaryl-CoA synthase (mHMGS) deficiency, Medium-chain acyl dehydrogenasedeficiency (MCAD), Long-chain acyl dehydrogenase deficiency (LCAD), Short-chain acyl dehydro-nase deficiency (SCAD), Long-chain 3-hydroxyacyl-CoA deficiency, Medium-chain 3-hydroxyacyl-Codeficiency, Pyruvate carboxylase deficiency, Porphyri a history of pancreatitis, active gall bladder disease, impaired liver function, impaired fat digestion, poor nutritional status, gastric bypass surgery, abdominal tumors, decreased gastrointestinal motility, a history of kidney failure.\nAll intellectual property in this program remains the copyright of Briggston Enterprises LTD and must not be copied or reproduced without explicit, written permission from the authors.\nThe complete program including the fully downloadable guide is accessible immediately after purchase. As a result our money back guarantee requires the following conditions are met.\nYou must provide:\n1) A date and time stamped photo of your weight from week 1, 2 and 3.\n2) A copy of your shopping receipts from week 1, 2 and 3.\nIf no weight loss occurs, we will refund your purchase price 100%. Any other refunds are at the complete discretion of Briggston Enterprises LTD.\nPrior to purchasing the Beyond your Belly program you must first read and agree to these Terms and Conditions.", "pred_label": "__label__POS", "pred_score_pos": 0.7930065989494324}
{"content": "Q79 - Horseplay\nQuestion:\nIn a warehouse, during a lunch break, two employees are participating in an online viral challenge where a person drops a piece of paper from the top of a flight of stairs and races down the stairs in time to catch the paper. The first employee is barely able to catch the paper in time. The second employee feels pressured to accomplish the challenge and ends up tripping while rushing down the stairs too quickly. He injures multiple body parts and ends up with bruises, cuts, broken bones and a concussion. Is it recordable?\nAnswer:\nYES. The injury is considered work-related because it occurred on company property during the workday and the injuries (broken bones) are severe enough to trigger recordability. Also, lunch is considered part of the normal workday and is not included in the list of exceptions for recordkeeping purposes.\nLetter of Interpretation: This case must be recorded because it does not meet the exception to work-relatedness in Section 1904.5(b)(2)(v) for injuries that occur in the work environment but are solely due to personal tasks. For the \"personal tasks\" exception to apply, the injury or illness must 1) be solely the result of the employee doing personal tasks (unrelated to their employment) and 2) occur outside of the employee's assigned working hours. OSHA clarified in a January 15, 2004 letter of interpretation that Section 1904.5(b)(2)(v) does not apply to injuries and illnesses that occur during breaks in the normal work schedule. Here, the exception does not apply because the injury occurred during the employee's lunch break\n1904.7(b)(7) What is a \"significant\" diagnosed injury or illness that is recordable under the general criteria even if it does not result in death, days away from work, restricted work or job transfer, medical treatment beyond first aid, or loss of consciousness? Work-related cases involving cancer, chronic irreversible disease, a fractured or cracked bone, or a punctured eardrum must always be recorded under the general criteria at the time of diagnosis by a physician or other licensed health care professional.", "pred_label": "__label__POS", "pred_score_pos": 0.7071442604064941}
{"content": "Rental and vacant property insurance Insurance that has been crafted to protect properties with unique risks.\nMarkel Specialty's rental and vacant property coverage can be customized for multiple risk types:\nOwner-occupied- for properties used as the primary residence Seasonal- for residences used as vacation homes Rented- for landlords who rent their homes to tenants Vacant- for unoccupied homes including those for sale\nOur focus and expertise is in writing property risks that frequently do not fit in the traditional insurance marketplace. This permits us to write a diverse set of risk profiles including:\nOlder homes Risks with prior claims Risks not supported by a companion homeowners or auto policy Customers who may have had a prior lapse in coverage Properties titled to corporations or trusts rather than individuals Properties titled to multiple individuals Modular homes Condominium units No restrictions on the number of insured locations\nOur rental and vacant property coverage permits you to tailor accounts to the specific coverage needs of the customer. This includes the ability to purchase combined property and liability coverages, property only or liability only.\nWe offer a variety of policy forms, optional coverages and discounts, including: Property coverage Protection for the primary structure. Basic and special policy forms are available permitting either replacement cost or actual cash value loss settlement. Contents coverage Basic and broad form level coverages can pay for damages to personal property and are available on either a replacement cost or actual cash value loss settlement basis. Additional living expense/fair rental value Optional coverages that help pay for expenses related to alternative housing when the insured property is uninhabitable due to a covered loss. Personal liability/premises liability Optional coverages if you become liable for damages or injury resulting from the use of your property. Additional options permit you to further enhance your protection and include: Unattached structures - covers losses on structures such as garages, sheds, and other unattached structures. Equipment breakdown - for sudden, accidental failure of electrical and mechanical systems built into the home, in addition to those purchased later. Vandalism coverage - this additional coverage helps pay for damages as a result of vandalism. Available discounts can include: Loss free discount Mature owners discount Newer residence discount Markel Specialty dwelling fire customers benefit from these program features: Convenient payment options Flexible policy terms Reliable, experienced claim service personnel If you have multiple properties to protect, you can enjoy the convenience of one policy, one bill, and one payment", "pred_label": "__label__POS", "pred_score_pos": 0.5093200206756592}
{"content": "Los Angeles DUI Lawyers with Answers DUI Checkpoints in Los Angeles\nDUI checkpoints are the familiar stops set up by police, often on holidays or other nights when large numbers of people are expected to be drinking, where each car must stop and officers typically ask drivers a few questions before allowing them to pass or having them pull over for further investigation.\nAre DUI checkpoints legal?\nYes. The United States Supreme Court has held that DUI checkpoints are legal, arguing that the interests of the government in stopping drunk drivers and reducing drunk driving fatalities were more important than the potential for intrusive searches and violations of privacy..[1] However, certain conditions must be met. A stop to find anything “suspicious” is illegal. However, a DUI checkpoint, solely for the purpose of stopping impaired drivers, is permissible.\nDUI checkpoints in the Los Angeles area must satisfy an eight-point test to be legal: Supervising officers must make all operational decisions. To “reduce the potential for arbitrary and capricious enforcement,” decisions about where, how, and when checkpoints operate must be made by supervising officer, not field officers. Motorists must be stopped based on neutral criteria. The decision of what vehicles to stop must be made in advance and based on “neutral, mathematical criteria.” For example, officers can stop every car, every other car, or every fifth car. Field officers cannot decide what vehicles to stop during the checkpoint. Also, officers may not decide to stop vehicles based on non-neutral criteria, such as certain types of cars or drivers of certain ages or ethnicities. The checkpoint must be reasonably located. There must be frequent DUI arrests or accidents in the location of the checkpoint. Adequate safety precautions must be taken. The time and duration must reflect “good judgment”. Sufficient indicia of its official nature. It must be clear to approaching drivers that they are approaching an official DUI checkpoint. For example, checkpoints can be indicated by signs, lights, marked police cars, and uniformed officers. Drivers detained a minimal amount of time. Drivers should only be detained long enough for officers to briefly question them and observer any signs of intoxication, such as the smell of alcohol, slurred speech, or bloodshot eyes. Checkpoints should be publicly advertised in advance[2]. Failure to advertise the checkpoint in advance, alone, will not make the DUI checkpoint illegal.\nIf you are arrested for DUI after being stopped at a checkpoint, it is essential to have a Los Angeles DUI attorney who is familiar with these factors and can challenge the constitutionality of the checkpoint based on exactly what transpired during the DUI stop.\nCan I really be stopped without probable cause?\nYes. If the DUI checkpoint meets the requirements, you can be stopped without any kind of individual suspicion. However, officers must have probable cause in order to arrest you.\nWhat are my rights at a DUI checkpoint in Los Angeles?\nIf you enter a checkpoint, you are required to stop for inspection.[3] However, during the stop you have the same rights you would have during any other traffic stop. You must provide your license and registration if asked. You may refuse to answer any questions during the stop.\nAdditionally, officers may not ask questions unrelated to the checkpoint.[4] For example, because the checkpoint is related to driving under the influence, officers are permitted to ask whether you have consumed any alcohol or other drugs, and related questions, such as how much you consumed and when. However, the officers are not permitted to ask questions unrelated to the checkpoint, such as immigration status.\nYou do not have to consent to a search of your person or vehicle. You may refuse to perform field sobriety tests. You may also refuse to blow into the PAS (Preliminary Alcohol Screening) Device[5], also known as a Breathalyzer. However, if arrested for a DUI, you are required to consent to a chemical blood alcohol test under California law.[6] If you refuse, you may face a year-long suspension of your driver’s license and an additional 48 hours in jail if you are convicted of DUI.[7] If you are arrested for a DUI, you have the right to request a blood or breath alcohol test.[8]\nWhat if I haven’t been drinking alcohol but I have been smoking marijuana?\nDUI checkpoints are not limited to driving under the influence of alcohol, and drivers can be arrested for driving under the influence of drugs, including marijuana. Although recreational marijuana was legalized by the passage of Proposition 64, driving under the influence of marijuana is still prohibited.\nBecause of a concern that legalization of recreational marijuana would lead to an increase in marijuana-related driving under the influence, law enforcement has stepped up its enforcement of marijuana DUIs. Officers at checkpoints will be looking for any signs that would allow them to arrest drivers for driving under the influence of marijuana, including the smell of marijuana, glassy or red eyes, or any visible marijuana or marijuana paraphernalia.\nHow do I find out where DUI checkpoints are in the L.A. area?\nMost police departments announce DUI checkpoints in advance through press releases and social media. They will also usually publish the announcement on their websites, usually in a “news” or “press” section. For example, the LAPD announces DUI checkpoints at lapdonline.org/newsroom.\nAdditionally, local news and newspapers, neighborhood pages, and apps, such as Waze, sometimes report on local checkpoints.\nFor updates on DUI checkpoints close to you, check out these websites: CA DUI Checkpoint Locations Facebook page Los Angeles County Orange County Riverside County San Bernardino County Time is of the Essence: Call a Los Angeles DUI Attorney Now\nIf you have been charged with a DUI offense after being stopped at a checkpoint, it is essential to hire a criminal defense attorney in Los Angeles who is experienced at challenging the legality of DUI checkpoints, in addition to challenging the evidence in typical DUI cases. The attorneys at Moaddel Law Firm are experienced in attacking the legality of DUI checkpoints, as well as defending misdemeanor and felony DUI cases.\nIt is crucial to hire a criminal defense attorney as soon as possible. An attorney can jump into action immediately, and potentially prevent the District Attorney’s Office from filing charges against you at all. Additionally, if you want to avoid a suspended driver’s license, you must contest the suspension at a DMV hearing. You must request your DMV hearing within ten days or you will lose the opportunity to contest the suspension. An attorney can request the hearing for you, as well as defend your rights at the hearing.\nYou face even worse consequences if convicted: heavy fines, restitution, and even jail time. Your future is on the line, so make sure you have trusted legal representation in your corner!\nArrested for DUI? Call Moaddel Law Firm right away—(877) 375-8188.\n[1]\nMichigan State Police Dept. v. Sitz (1990) 496 U.S. 444.\n[2]\nIngersoll v. Palmer (1987) 43 Cal.3d 1321\n[3] Vehicle Code § 2814.2(a).\n[4]\nPeople v. Valenzuela (1994) 28 Cal.App.4th 817, 826.\n[5] Vehicle Code 23612(h).\n[6] Vehicle Code § 23612.\n[7]\nId.\n[8] Vehicle Code § 23612(d).\n[/fusion_text][/fusion_builder_column]", "pred_label": "__label__POS", "pred_score_pos": 0.5504838228225708}
{"content": "Executive Summary The commodity complex is already beginning to rise following oil's upside breakout Natural gas is trending higher Copper appears to have bottomed Wheat and coffee's downtrends are ending A secular rise in commodities can happen even in the face of slower economic growth and lower demand\nIf you have not yet read Part I: Get Ready for Rising Commodity Prices available free to all readers, please click here to read it first.\nIn Part I, we examined the conventional narratives used to explain the price of oil and found that they no longer account for oil’s breakout to a new uptrend. I suggested that financialization and speculation could power oil much higher, despite sagging global demand for physical oil and a potentially deflationary global recession.\nThis thesis has been met with widespread skepticism when I’ve aired it privately, and I think this skepticism arises from the newness of this narrative. In the past, oil has responded to supply-demand and inflation/deflation. The notion that oil could rise in a finance-induced “scarcity amidst plenty” is neither simple nor intuitive.\nIf oil tracks higher, we can anticipate that the primary commodities (energy, agricultural, and construction) may well rise, even as end-user demand weakens, as oil underpins all production and transport. The 2.5% rise in producer prices over the past year suggests this is already occurring.\nThe secondary reason is that lower prices eventually push marginal producers out of business, tightening supply and giving the remaining producers pricing power.\nAs noted in Part I, regardless of what we see as key drivers or what we think oil “should do,” oil has broken out technically.\nIs there any evidence to support the idea that the uptrend in oil will trigger higher prices in other commodities? Let’s start with the CRB (Commodity Research Bureau) index that reflects a basket of commodities…\nRead More »", "pred_label": "__label__POS", "pred_score_pos": 0.5810034871101379}
{"content": "Westbrook, P., Heffner, L., La Peyre, MK. 2019. Oyster-mediated nutrient bioassimilation, burial and denitrification: effects of timing and location. Marine Biology 166:4. Abstract\nRestoration of oyster habitat across Louisiana may offer a valuable approach to mitigating anthropogenic nutrient inputs to coastal estuaries. The eastern oyster (Crassostrea virginica) and the reefs they create provide significant ecosystem services, including potential nutrient mitigation via bioassimilation, burial, and oyster-mediated denitrification. This study measured bioassimilation, burial, and oyster-mediated sediment denitrification in near-shore shallow-water (< 1 m water depth) and deep-water (> 1 m water depth) oyster reefs in Louisiana. Carbon (C) and nitrogen (N) in shell and tissue was within the range of previous studies, but was found to be influenced by reproductive status, size, and habitat type. Changes in tissue percent N and C post spawning combined with significant reductions in tissue weight from the release of gametes, resulted in 20 and 46% reduction in tissue N and tissue C load (mg) for a 100 mm oyster, respectively. Percent N and C buried in sediments were highest at shallow-water reefs (0.52 0.05% and 8.92 0.89% respectively), likely due to their close proximity to the marsh edge and thus exposure to a greater influx of detrital material. Closed-system ex-situ incubations indicated net denitrification in all habitat types studied, with the highest rates exceeding 600 µmol m-2 hr-1 during the summer, but no enhancement attributable to oyster reefs specifically. Considering the large extent of reefs and oyster production across coastal Louisiana, oyster habitats may still contribute to nutrient mitigation, but their unique contribution likely comes from bioassimilation, and removal of tissue and or shell from the system. Efforts to predict oyster reef nutrient mitigation requires incorporating timing of harvest and habitat context.", "pred_label": "__label__POS", "pred_score_pos": 0.9450988173484802}
{"content": "On February 22nd, 2017, CCHO sponsored the ISSP, Institute of Public Health at St. Joseph University event. A scientific presentation entitled” New Challenges of Healthcare Systems: Impact on Quality and Performance” and animated by Dr. Dabbous, highlighted the new challenges governments are facing worldwide: mainly the rising cost of innovative health technology. These confrontations are specifically faced in oncology, orphan, and chronic diseases. He also elaborated the new trends shaping the systems worldwide as HTA units and their roles in informing policy makers and payers, and the BIG data paralleled with the digital health.\nThe presentation was very rich and exciting. By the end of the talk, participants representing officials and professionals from different healthcare institutions and universities in Lebanon, debated over several healthcare decision making policies and processes. Some discussions were on: payment models and rewards, capping policies, patients’ engagement role, healthcare data generation and availability, quality measures, and other. This left the audience with a lot of thought provoking messages and ideas to help initiate the examination on healthcare access, cost, and quality.\nThe conference was followed by a reception at the Medical Faculty Campus.", "pred_label": "__label__POS", "pred_score_pos": 0.9893545508384705}
{"content": "Grover, Christopher (2010)\nAbolishing the 10p tax band:some observations. Journal of Poverty and Social Justice, 18 (1). pp. 69-79. ISSN 1759-8273 Abstract\nIn his last Budget as the UK’s Chancellor of the Exchequer in 2007, Gordon Brown abolished the 10p starting rate of income tax. This was to prove to be a controversial move and one that was of significance for income maintenance policy. This article focuses on this significance by examining the competing economic, political and social objectives that framed the abolition of the 10p tax band, the messages that its abolition sent to low paid childless workers and the impacts of its abolition.", "pred_label": "__label__POS", "pred_score_pos": 0.5951100587844849}
{"content": "Beattie, Vivien and Smith, Sarah-Jane (2013)\nValue creation and business models:refocusing the intellectual capital debate. British Accounting Review, 45 (4). pp. 243-254. ISSN 0890-8389 Abstract\nThere is currently significant debate worldwide regarding business reporting. The concept of the ‘business model’ has entered into the discourse, as has the concept of ‘integrated reporting’, adding to the established debate regarding accounting for intangible assets and, more generally, intellectual capital (IC). Despite the tradition of extensive interdisciplinary borrowing in accounting, relevant literatures on business models and on modern managerial perspectives on competitive advantage have, to date, largely been ignored within the accounting literature. The main contribution of this conceptual paper is to identify and discuss the key features of these literature strands and their linkage to contemporary debates on narrative reporting. These conceptual linkages between IC, value creation and business models are illustrated by means of interview evidence from eleven company cases. It is concluded that the business model concept offers a powerful overarching concept within which to refocus the IC debate. The concept is holistic, multi-level, boundary-spanning and dynamic. The analysis supports the current calls for integrated disclosure around the central business model story. Suggestions for future research are offered.", "pred_label": "__label__POS", "pred_score_pos": 0.91749507188797}
{"content": "Semantic segmentation with dense pixel-wise annotation has achieved excellent performance thanks to deep learning. However, the generalization of semantic segmentation in the wild remains challenging. In this paper, we address the problem of unsupervised domain adaptation (UDA) in semantic segmentation. Motivated by the fact that source and target domain have invariant semantic structures, we propose to exploit such invariance across domains by leveraging co-occurring patterns between pairwise pixels in the output of structured semantic segmentation. This is different from most existing approaches that attempt to adapt domains based on individual pixel-wise information in image, feature, or output level. Specifically, we perform domain adaptation on the affinity relationship between adjacent pixels termed affinity space of source and target domain. To this end, we develop two affinity space adaptation strategies: affinity space cleaning and adversarial affinity space alignment. Extensive experiments demonstrate that the proposed method achieves superior performance against some state-of-the-art methods on several challenging benchmarks for semantic segmentation across domains. The code is available at https://github.com/idealwei/ASANet.", "pred_label": "__label__POS", "pred_score_pos": 0.9893057942390442}
{"content": "ABSTRACT\nThe study aims to develop a legal principle that can be applied either within the constitutional framework of International Economic Law, or as a decision-making tool in the dispute settlement of the WTO where economic, social and environmental factors are in tension detrimentally to each other. The concept of balance constitutes a constitutional fundamental in handling with the systemic relationships between three inseparable, equally legitimate interests. The integrative process of globalisation challenges international law to develop coherent approaches that meet goals and common interests of the international community. The principle of balance is therefore oriented conceptually on common values, though retaining in essence the neutrality and objectivity of a legal principle. The paper suggests a balance test as a practically applicable decision-making instrument that should keep an overall integrated, systemic approach, yet with due regard to individual needs existent within any system. Furthermore, it is suggested that active co-operation and mutual harmonic complementation should be fostered between economic, social and environmental factors as they serve the same common values such as human rights and the environment.", "pred_label": "__label__POS", "pred_score_pos": 0.5903163552284241}
{"content": "1/15/2018\nNutrition is the backbone of performance in sports. Best nutrition practices before, during and after workout/game day are essential for optimized performance and the nutrition goals for each is different. Success or defeat, the post-game or post-exercise period is crucial to restore the body with the lost nutrients and allow it recover.\nRecovery is a challenge for athletes who undergo two or more sessions of training every day or participate in multiple events in one given day. In such scenarios, the work-to-recovery ratio do not match, and the best possible thing is to start an event with maximum energy.\nDuring the recovery period, an athlete needs:\nRecommended Foods for Recovery", "pred_label": "__label__POS", "pred_score_pos": 0.9884746670722961}
{"content": "Knowing the true value of your assets is crucial to understanding your overall financial position. An accurate valuation starts with an understanding of your business – we take the time to learn about your business: the operations, key individuals, the industry, and future expectations. As a result, our firm can provide you with an accurate, comprehensive, and independent appraisal of your business, whether it be a small business that has been around for awhile or a blossoming startup.", "pred_label": "__label__POS", "pred_score_pos": 0.9976081252098083}
{"content": "Abstract\nCerebral edema is the most significant complication in children with diabetic ketoacidosis (DKA). Our goal was to study whether subclinical cerebral edema was preferentially vasogenic or cytotoxic. Magnetic resonance imaging (MRI) - diffusion-weighted imaging (DWI) and T2 relaxometry (T2R) - were obtained in pediatric patients presenting with severe diabetic ketoacidosis (DKA) 6-12 hours after initial DKA treatment and stabilization and 96 hours after correction of DKA. T2 relaxometry was significantly increased during treatment in both white and gray matter, in comparison to the absolute T2R values 96 hours after correction of DKA (p = .034). Classic intracellular cytotoxic edema could not be detected, based on the lack of a statistically significant decrease in ADC values. ADC values were instead elevated, implying a large component of cell membrane water diffusion, correlating with the elevated white and gray matter T2R. We discuss the findings in relation to cerebral blood volume, cerebral vasoregulatory dysfunction, and cerebral hyperemia.\nKeywords Cerebral edema Cerebral hyperemia Diabetic ketoacidosis Magnetic resonance imaging ASJC Scopus subject areas Endocrinology", "pred_label": "__label__POS", "pred_score_pos": 0.7387509942054749}
{"content": "My general area of research focuses on understanding the influences between localized bathymetry and the surrounding water column. As much of this work is on a scale logistically difficult (e.g. large scale shorelines) or impossible (e.g. under-ice) to survey with traditional techniques, I have worked since 2006 with Autonomous Underwater Vehicles (AUVs) as data collection platforms to further my research. My research aim is to continue developing a engineering research group with these vehicles and other emerging technologies to address pioneering scientific questions. The aim requires expertise in varied domains including: (i) environmental fluid mechanics; (ii) bathymetric mapping; and,(iii) invasive species identification and ecosystem assessment. Bringing together these diverse fields, enables an understanding of aquatic habitat and ecosystem assessment not previously available.\nNathan Kemp (Blue Ocean Monitoring – Australia), Damien Guihen (Australian Maritime College – University of Tasmania) and Alex Forrest (University of California – Davis) ballasting an AUV for deployment at South Korean Jang Bogo Station in Antarctica (January, 2017)\nIn a broader sense, from lakes to oceans, I believe in having the right tool for job at hand have worked with a wide variety of conventional and leading edge techniques to observe and monitor our water resources. From developing glider systems for ongoing work at Lake Tahoe to modelling sediment transport around water infrastructure, each tool expands our capacity for observation in a world that’s inherently complex and transdisciplinary in nature.", "pred_label": "__label__POS", "pred_score_pos": 0.6866008043289185}
{"content": "Household air pollution and health: a Multi-country LPG Intervention Trial-Core\nLocation(s): Rwanda; India; Guatemala; Peru\nDescription\nThis study is a randomized controlled trial of liquefied petroleum gas (LPG) stove and fuel distribution in 3,200 households in four countries (India, Guatemala, Peru, and Rwanda). Following a common protocol, each intervention site will recruit 800 pregnant women (aged 18-34 years, <20 weeks gestation), and will randomly assign half their households to receive LPG stoves and a 30-month supply of LPG. Controls will receive the same cookstoves and LPG supply at the end of the study. The mother will be followed along with her child until the child is 2 years old. The researchers estimate that 25% of households will have a second, non-pregnant older adult woman (aged 35-64 years) who will also be enrolled at baseline and followed during the 30-month follow-up period. To optimize intervention use, the researchers will implement behavior change strategies informed by previous experiences and formative research in Year 1. This study will assess cookstove use, conduct repeated personal exposure assessments of household air pollution, and collect dried blood spots and urinary samples for biomarker analysis and biospecimen storage. The primary outcomes are low birthweight, pneumonia incidence, and linear growth in the child, and blood pressure in the older adult woman. Secondary outcomes include preterm birth and gross motor development in the child, maternal blood pressure during pregnancy, and endothelial function, respiratory impairment, carcinogenic metabolites, and quality of life in the older adult woman.", "pred_label": "__label__POS", "pred_score_pos": 0.6857070922851562}
{"content": "MYB activation is proposed to underlie development of adenoid cystic cancer (ACC), an aggressive salivary gland tumor with no effective systemic treatments. To discover druggable targets for ACC, we performed global mRNA/miRNA analyses of 12 ACC with matched normal tissues, and compared these data with 14 mucoepidermoid carcinomas (MEC) and 11 salivary adenocarcinomas (ADC). We detected a unique ACC gene signature of 1160 mRNAs and 22 miRNAs. MYB was the top-scoring gene (18-fold induction), however we observed the same signature in ACC without detectable MYB gene rearrangements. We also found 4 ACC tumors (1 among our 12 cases and 3 from public databases) with negligible MYB expression that retained the same ACC mRNA signature including over-expression of extracellular matrix (ECM) genes. Integration of this signature with somatic mutational analyses suggests that NOTCH1 and RUNX1 participate with MYB to activate ECM elements including the VCAN/HAPLN1 complex. We observed that forced MYB-NFIB expression in human salivary gland cells alters cell morphology and cell adhesion in vitro and depletion of VCAN blocked tumor cell growth of a short-term ACC tumor culture. In summary, we identified a unique ACC signature with parallel MYB-dependent and independent biomarkers and identified VCAN/HAPLN1 complexes as a potential target.", "pred_label": "__label__POS", "pred_score_pos": 0.9449462294578552}
{"content": "On Tuesday 16 April the Ministries of Foreign Affairs and Education, Culture and Science organized a Round Table at the Migration Museum, The Hague, in preparation for the development of a new framework on International Cultural Policy 2021-2024.\nPart of this framework is about Shared Cultural Heritage. The gathering’s objective is to gain insights and ideas related to Shared Cultural Heritage and how these can be integrated into new policies. We discussed about the value of immaterial heritage, material heritage and how it is interconnected, which countries should be part of the program, what topics are currently relevant and urgent, such as climate change. Best practices and brilliant failures were shared, knowledge was shared and there was space for networking.\nI shared my experience on TF, the cultural exchange between artists and designers and craftsmen, on how we work with immaterial heritage and also on how it is encouraged to exchange knowledge, based on equality and reciprocity, through experiments, explorations and dialogues.\nNecessary cookies are absolutely essential for the website to function properly. This category only includes cookies that ensures basic functionalities and security features of the website. These cookies do not store any personal information.", "pred_label": "__label__POS", "pred_score_pos": 0.7237308025360107}
{"content": "MANILA, Philippines – A Commission on Audit report released on Wednesday, July 13, showed that P6.39 billion in transactions under the Pantawid Pamilyang Pilipino Program (4Ps) remain unliquidated as of December 2015.\nAlso known as the Conditional Cash Transfer (CCT) program, the state's flagship anti-poverty program had a budget of P62.3 billion in 2015.\nThe Land Bank of the Philippines and the Department of Social Welfare and Development (DSWD) have a memorandum of agreement (MOA) on the payout of cash assistance to the 4Ps beneficiaries. Under the MOA, Landbank is to submit liquidation documents within 5 days from the last date of the scheduled payout.\n\"Submission of liquidation documents by Land Bank of the Philippines was delayed, thus, status of P6.391 billion unliquidated balance as of CY 2015 cannot be assessed,\" it said in its report.\nThe total unliquidated amount includes P3.322 billion in transactions from 2008 to 2014.\nState auditors also noted \"recurrent deficiencies\" in the program's implementation, including the failure to remit back to the DSWD some P1.579 billion in unused 4Ps funding. This amount was not released as the beneficiaries were delisted for non- compliance with the program's requirements.\nThe COA also discovered that P1.252 billion in cash grants did not reach the intended households, and an inaccurate information system excluded or suspended some validated compliant beneficiaries and allowed \"327 households with duplicate names under different household IDs.\"\nThe COA also pointed out 386,425 beneficiaries' accounts with a cumulative balance of P139.008 million had no withdrawals since the accounts were set up. This, it said, indicated that the households no longer needed immediate assistance under the 4Ps, despite being enrolled in the program.\nThe COA said, however that even with these problems, the program has benefited millions of poor families, allowing them to send their children to school. The program currently has 4.4 million household-beneficiaries.\n\"On a positive note, the Program has conducted the first graduation event... highlighting the 333,673 beneficiaries who graduated with the help of the program. Out of the total number of graduates, 13,469 graduated with honors,\" COA said.\nAmong the graduates were 1,312 valedictorians and 1,024 salutatorians.\n– Rappler.com", "pred_label": "__label__POS", "pred_score_pos": 0.6285355091094971}
{"content": "Schools and academies over the last decade have faced significant financial pressures, further exacerbated due to the current COVID-19 global pandemic. However, central government are reacting to these current pressures and have announced additions to school funding for the academic year 2021/22 alongside the increase in per pupil funding previously announced. These changes in funding aim to increase the opportunities for pupils across the UK and intend to return education back to normal.\nThe funding figures released highlight how each pupil will benefit in the second and third years of central government’s school funding settlement which is worth a total of £14.4 billion over a three year period. During the coming academic year (2020/21) schools will benefit from an increase in per pupil funding to a minimum of £3,750 for a primary pupil and a minimum of £5,000 for a secondary pupil. The funding will continue to deliver on the Prime Ministers pledge to increase education funding and provide all young people with the same opportunities to succeed, regardless of where they grow up or which school they attend.\nFor 2021/22 Central government has pledged a minimum of £5,150 per pupil for secondary schools and a minimum of £4,000 per pupil for primary schools, a further increase from the 2020/21 per pupil allocations.\nThe increased funding will be allocated using the national school funding formula (NFF) which has been formulated to fairly allocate funding to meet the needs of pupils in all types of schools. Funding for small and remote schools will also see an increase by over 60% to overcome the financial challenges that these schools can face.\nGavin Williamson, the Education Secretary has said:\n“Not only are we confirming another year of increased and better-targeted funding for our schools, but with our transformative national funding formula we are making sure the money is distributed fairly across the country so all schools can drive up standards.”\nIn addition to the increased funding allocation via the NFF, schools are set to receive significant investment from the Government’s £1 billion COVID catch up package in the next academic year. This intends to provide support for schools due to the lost teaching time and other challenges caused by COVID-19. The allocations for this funding will be determined by pupil numbers and will be paid once a term over the 2020/21 academic year.\nAs stated by Boris Johnson,\n“our £1 billion COVID catch up package, on top of these increases in per-pupil funding will help teachers support those who have fallen behind while out of school, and deliver a superb education for all children across the country”\nThe government is also offering a £350 million tutoring fund as a second part to the catch-up funding. This aims to provide support for disadvantaged pupils aged 5-16 in schools and colleges.\nFrom the second half of the 2020/21 autumn term, the national tutoring programme will provide additional support to disadvantaged pupils through providing heavily subsidised tuition from approved partners and also offer in house academic mentors to provide intense support for pupils.\nThe government has pledged various funding initiatives to provide financial support so schools can meet the needs of their pupils and make certain all students can reach their maximum academic potential. To be sure you stay up to date with DfE guidance or if you require additional information regarding future school funding and initiatives / finance support, please contact us using the button below.", "pred_label": "__label__POS", "pred_score_pos": 0.8810100555419922}
{"content": "Many people are reluctant to share their personal issues with others. However, it's best to have a shoulder to lean on when making decisions regarding your wellbeing and that of your family. There are many reasons you should hire a family lawyer to handle your family-related issues. These include divorce matters, child custody and prenuptial agreements. Here's a look at these issues in greater detail.\nDivorce Matters\nIn Australia, divorce is granted if a couple has irreconcilable differences. This could range from issues related to the promiscuity of one of the spouses to domestic violence. A family lawyer can help you finalise your divorce in the shortest time possible.\nYour lawyer will undertake the duty of handling the divorce papers to your spouse. They will also file the divorce papers in court and handle all court-related proceedings. In the end, your lawyer will ensure you get the most favourable judgment in terms of division of property, child support, and spousal maintenance.\nChild Custody\nIn Australia, the law supports equal parenting by divorced couples. The law requires that the children of separated couples have a meaningful relationship with both their parents. Therefore, the court will most likely rule in favour of shared parental custody and responsibility.\nHowever, if you're not satisfied with the court's ruling, a family lawyer can help you get sole custody. Some of the conditions under which you may be able to get sole child custody are if your ex-partner isn't mentally stable, has a tendency of domestic violence, abuses substances or has reckless behaviour around the child.\nPrenuptial Agreements\nA family lawyer will not offer you advice and help only when things go wrong in your family. They will advise you on how to secure yourself against a future divorce or separation that puts your assets in jeopardy. Furthermore, you might want to secure the future of your child through child support provisions and other conditions in the prenuptial.\nIn this case, you can go to a lawyer for advice and assistance with a prenuptial agreement. The main benefits of prenuptial agreements are certainty and tax benefits. Your lawyer will help merge your interest with those of your partner to come up with a reasonable prenuptial contract. This contract will detail how assets and other responsibilities will be split in case of a divorce.\nAdditionally, your solicitor will ensure you get tax benefits by agreeing to a binding financial agreement (BFA). This means in case of a prenuptial; you stand to gain significant savings on capital gains tax, among other benefits.", "pred_label": "__label__POS", "pred_score_pos": 0.6399680376052856}
{"content": "We investigate an internal surge of Karayaylak Glacier, which was reported by the media in May 2015. To differentiate the May 2015 glacier surge from other glacier advances, we surveyed changes in velocity, crevasses and glacier area using Landsat 8 OLI L1T, ZY-1-02C and Gaofen-1 images from October 2014 to July 2015. The velocity, measured by automatic feature extraction and tracking during the active phase, was 10–100 times the velocity during the quiescent phase, with a maximum of (20.2 ± 0.9) m d−1 (mean ± standard error) from 8 to 15 May 2015 in the west branch of the glacier. The surge initiation and termination took place from 13 April to 16 June 2015. Ice in the west branch (length, 7 km; area, 6.8 km2) of Karayaylak Glacier accelerated down to the east branch, leading to the development of crevasses and ice covering an additional 0.1 km2 of summer pasture on the northwestern side. However, we detected no advance of the glacier's terminus.", "pred_label": "__label__POS", "pred_score_pos": 0.9948791265487671}
{"content": "Cannabidiol is all the rage in natural health circles. This cannabinoid is excellent at treating many common ailments, including chronic pain, sleeplessness, anorexia, and anxiety. You can purchase CBD supplements, but some people prefer to ingest CBD in the most natural form possible. This has its benefits since unprocessed hemp contains all its natural cannabinoids, not just CBD; these cannabinoids may work together to produce positive synergistic effects.\nIf you'd like to supplement your diet with CBD in its purest form, look no further than hemp buds. Hemp buds, also known as hemp flower, are harvested from the hemp plant before they bloom. One of the most enjoyable and medicinal strains of hemp is known as Acid Rock. Here are three tips that will help you make the most of your Acid Rock hemp flower:\n1. Smoke in an area where the smell won't pose issues.\nOne of the easiest ways to consume hemp flower is by smoking it. Hemp buds can be broken apart by hand or with the help of a grinder. The finely ground hemp buds can then be rolled into a joint or smoked from a pipe. However, Acid Rock hemp carries a particularly strong scent. Many people find the smell enjoyable, but you may not want to continue smelling the smoke for hours. Smoke your Acid Rock hemp outdoors, if possible. Try to be considerate by staying away from crowds. While hemp flower is legal, its scent is similar to cannabis, which may alarm passersby.\n2. Consider using a vaporizer.\nIf you don't want to deal with the hassle of hemp smoke, you can vape your Acid Rock hemp flower instead. Vaping is an efficient way to reap the benefits of CBD. Hemp vaporizers have a chamber that you can pack with ground hemp buds. Once you turn the vaporizer on, it will heat the hemp until the CBD and moisture inside vaporize. The vapor can then be drawn into your lungs the same way you'd smoke a cigarette. Since vaporizers won't burn your hemp, they're a way to enjoy your Acid Rock hemp without worrying about the lingering scent of smoke.\n3. Keep your hemp flower tightly sealed.\nWhen your Acid Rock hemp flower arrives, it will be fresh and fragrant. Fresh hemp flower should be slightly sticky to the touch. For maximum potency, don't allow your hemp buds to dry out. Immediately transfer your Acid Rock hemp flower into a tightly sealed container. Keep your container in a cool area away from direct sunlight.\nShare", "pred_label": "__label__POS", "pred_score_pos": 0.5710333585739136}
{"content": "Keeping Rail Safety on Track\nWe at GCG have extensive experience in managing processes across the entire rail sector, and are fluent in the Rail Operators obligations and providing practical WHS management solutions.\nWe frequently assess and review hazardous chemical transports across multiple stakeholder entities (the transfer of goods between duty holders), and facilitate risk workshops for contractor management, rail carriage safe design, operator ergonomics, and public access/egress (including station transfers).\nComplementing our processes are our network of industry-leading personnel, who collaborate with clients to facilitate lasting solutions.\nWe are familiar with role of the Office of the National Rail Safety Regulator (ONRSR), and the goal to align Australian Rail Safety Management to a risk-based approach across the industry.\nWe regularly work alongside clients in the rail industries for: Coaching and mentoring of contract supervisors and management of workers. Identifying and analysing the transportation of hazardous chemicals across the rail network. Designing systems protecting workers when handling hazardous chemicals. Risk observations with a focus on human interaction and heuristic learning behaviours. Promote safety culture from a negative to a positive influence. Identify areas where the safety design is incomplete and provide solutions.", "pred_label": "__label__POS", "pred_score_pos": 0.9516293406486511}
{"content": "In Connecticut, there are various different grounds that can lead to a business dispute. Often, prior agreements and contracts have terms that the businesses disagree upon. Disputes can also occur over property matters, billing issues or other disagreements.\nWhat to Do in a Business Dispute?\nIf involved in a business dispute in Norwich, Connecticut, reviewing any relevant documents, especially contracts, should be the first step. These documents might decide how the dispute will be resolved. Not all contracts have dispute resolution clauses, of course, and occasionally neither business has any documents relevant to the dispute at all. If that is the case, a court might be needed to resolve the dispute. Connecticut courts will look to your specific case and try to discover the best resolution. In determining the outcome, they will use a specific set of legal principles designed for situations where the parties have not agreed beforehand on how to handle a dispute. There are laws specific to each state that govern how to approach dispute resolution. Lawyers practicing in Norwich are best suited to offer advice in accordance with Connecticut law. Negotiations might also proceed more smoothly when an attorney is consulted, which may even lead to a resolution outside of court.\nAlternative Dispute Resolution\nMost contracts have terms that will decide how a dispute is handled. These are often referred to as Alternative Dispute Resolution or ADR clauses. These methods of resolution include Mediation and Arbitration, among others. ADR is designed to reach the same conclusion as a court, but without the cost and inconvenience of actually appearing before a judge. Nevertheless, each form of ADR carries its own set of protocol, often involving a neutral third party that resolves the conflict according to the law. An attorney experienced in Alternative Dispute Resolution can help you with your business dispute in Norwich if it is to be resolved out of court.", "pred_label": "__label__POS", "pred_score_pos": 0.6275299787521362}
{"content": "When atoms are heated or subjected to an electric discharge, they absorb energy, which is subsequently emitted as radiation. Actually electrons in an atom or a molecule absorb energy and get excited, they jump from a lower energy level to a higher energy level and they emit radiation when they come back to their original states.\nFor example, if sodium chloride is heated in the flame of a burner, sodium atoms are produced which gives rise to the characteristic yellow flame color. Similarly, if a discharge is passed through hydrogen gas (H2) at low pressure, some hydrogen atoms (H) are formed, which emit light in the visible region. This phenomenon accounts for the emission spectrum through hydrogen, better known as the hydrogen emission spectrum.", "pred_label": "__label__POS", "pred_score_pos": 0.7004650831222534}
{"content": "Choose your pension option This important decision will determine the amount of your lifetime monthly pension payments and the amount your spouse or beneficiaries may receive when you die. Temporary annuity option\nIf you retire before age 65, you may choose a temporary annuity to top up your pension. A temporary annuity increases your monthly payment until you reach age 65 or your death, whichever comes first.\nWhy choose a temporary annuity?\nBuying a temporary annuity may help you meet the initial expenses of retirement, such as paying off a mortgage before you turn 65. If you choose a reduced pension, a temporary annuity would increase your monthly pension payments until age 65. For those with significant taxable assets such as RRSPs, a temporary annuity can help lower your income after age 65 and therefore reduce tax on income.\nImportant things to keep in mind:\nA temporary annuity will reduce your lifetime pension. The younger you are when you retire, the bigger the impact on your pension after age 65. A reduced lifetime pension might have a significant impact on your spouse or dependants. The temporary annuity amount is based on the maximum old age security (OAS) benefit. Amounts may change from year to year to reflect fluctuations in the OAS, but your payments will remain stable from your retirement date onwards.\nYou can use the personalized pension estimator in My Account to see how a temporary annuity would affect your basic lifetime pension. This will help you determine what your pension amount will be before and after age 65.\nHere is an example of what these options could look like for a member retiring at 56 years old with a pension effective date of November 1, 2019, where their:\nLifetime pension = $2,100 Temporary annuity = $600\nOption Temporary annuity amount Pension payable to age 65* Pension payable after age 65 No temporary annuity $0 $2,100 $2,100 Temporary annuity $600 $2,466 $1,846\n*Please note that this amount does not include a bridge benefit.", "pred_label": "__label__POS", "pred_score_pos": 0.8297942876815796}
{"content": "How many times are we faced with a situation that seems so overwhelming that all we have to offer is fear? Perhaps a friend is making decisions that seem strange or unfamiliar to us. Or perhaps there is illness in our family. Any of life’s situations can bring us into this overwhelming state of fear.\nThe challenge is to sit with the fear, accept it, let it overwhelm you, but without immediate action. My guess is that the fear will turn into prayer for the person or situation.\nThe calm of prayer will replace the anxiety of the fear.", "pred_label": "__label__POS", "pred_score_pos": 0.7936490774154663}
{"content": "14 January 2020\nThe killing of Gen. Qassem Suleimani is not justified under international law. This attack was a violation of Iraq’s sovereignty and an act of war against Iran. It has increased tension and raised the risk of conflict in an already difficult situation. The tragic unintentional downing of the Ukrainian aircraft by an Iranian missile highlights the peril that can arise at moments of intense crisis.\nThe American rejection of the Iran nuclear deal (JCPOA) has contributed to this escalating confrontation and has made it more, not less, difficult to constrain Iran’s nuclear program. Salvaging the JCPOA would help defuse this ongoing crisis while addressing nonproliferation concerns.\nPugwash appeals to all parties to avoid further escalatory steps that could lead to a disastrous conflict and calls on the international community and the UN urgently to seek a peaceful resolution of the current dangerous situation.\nPaolo Cotta-Ramusino, Italy Secretary General of Pugwash\nSergio Duarte, Brazil, President of Pugwash\nSaideh Lotfian, Iran, Chair of Pugwash Council\nSteven Miller, US, Chair of Pugwash Executive Committee", "pred_label": "__label__POS", "pred_score_pos": 0.956188440322876}
{"content": "“Do you make regular visits to yourself?” RUMI\n“I recently learned of the work of Les Fehmi, a psychologist and researcher who for decades has been clinically documenting the profound healing that arises from “resting in open awareness.” Experimenting with student volunteers, Fehmi tracked their EEG readings as they visualized peaceful landscapes, listened to music, watched colored lights, or inhaled various essential oils. But it was only after he posed the question, “Can you imagine the space between your eyes?” that their alpha wave levels truly soared. He posed another question, “Can you imagine the space between your ears?” The subjects alpha waves spiked again. Fehmi named this term, “Open Focused Attention.” The key was inviting attention to space (or stillness or silence in timelessness) and shifting to a non- objective focus. In contrast, open-focused attention rests the brain. With a sustained pause from processing information from memories, plans, and constant thoughts about self, our brain waves slow down into synchronous alpha. Our muscles relax, stress hormone levels are lowered, blood flow is redistributed.”\nTrue Refuge – Tara Brach PH.D.\nWe can practice this effect when sitting quietly and looking at the blue sky; in the silence before a sunrise; in the pause and stillness after a snowfall, or staring at the starlit night sky; or visualizing and focusing on the space within every part of our body. When we practice this regularly, we learn to resonate with such moments because they connect us with the most intimate sense of who we are, and the infinite space within and around us.", "pred_label": "__label__POS", "pred_score_pos": 0.9672774076461792}
{"content": "For runners, their feet and ankles play critical roles when it comes to performing in their sport. If you’re a runner, then keep reading to discover what your podiatrist in Chicago would want you to know about your foot and ankle health.\nSkin Care\nMany runners overlook the importance of caring for their skin, which can lead to problems like cracked heels and blisters. If you’re prone to dry skin, then apply moisturizer to your feet each day, ideally after a shower or bath. If you frequently suffer from blisters, then invest in well-fitting socks and consider lubricating them on the outside, which may reduce the friction between your foot and the shoe. Also, opt for moisture-wicking socks, which can help prevent foot fungus.\nTraining Tips\nYour feet and ankles are built to handle a lot, but overdoing it can put you on a fast track to injury. To prevent being sidelined, it’s important to avoid overuse, which is a common cause of chronic injuries that many runners experience, such as Achilles tendinitis and plantar fasciitis. To help keep your feet and ankles healthy and pain-free, don’t train on a sprained ankle or foot injury, avoid sudden increases in your training, stretch afterward, and replace your shoes frequently.\nFootwear Advice\nSpeaking of shoes, the ones that you wear can have a significant impact on your foot and ankle health. Rather than focusing on models or brands, finding shoes that fit your feet properly can help prevent problems like calluses, blisters, bunions, and pinched nerves. If you have wide or narrow feet, then start with footwear brands that offer width sizing. Also, have your feet measured each time you buy new shoes and enlist the help a shoe-fitting specialist, if possible. To maintain your footwear, store them away from hot or cold temperatures, as these can affect their fit and cushion. Finally, if you’re worried that not drying them in the sun will leave you with damp shoes, then consider buying two pairs and alternating between them.", "pred_label": "__label__POS", "pred_score_pos": 0.5564401745796204}
{"content": "Overview Global Drone Transponder Market is anticipated to reach USD 2,998 Million by 2024 at a CAGR of 6.68% during the forecast period.\nIn the last few years, drones were used for various industrial applications, including aviation, construction, mining, oil & gas, telecom, and logistics. The rise in the use of drones in these industries is driven by benefits over conventional manual inspection technologies; the use of drones helps save lives, time, and costs.\nSegmental Analysis\nThe global drone transponder market has been segmented on the basis of type, platform, fit, application, and drone weight.\nBy type, the market has been classified as ADS-B compatible and ADS-B non-compatible. The ADS-B compatible segment is projected to dominate the market. It was valued at\nUSD 1,486.1 million in 2018 and is expected to reach USD 2,262 million by 2024. Onboard sensors on drones are ineffective in ensuring collision avoidance. Thus, transponders, such as the ADS-B compatible, are being developed to ensure airspace safety and increase situational awareness, thereby reducing collision risks. ADS-B technology helps drone operators sense and avoid possible collisions. The ADS-B non-compatible segment is anticipated to exhibit a CAGR of 5.60% during the forecast period.\nBased on platform, the global drone transponder market has been divided into fixed-wing and rotary-wing. The fixed-wing segment is expected to lead the market during the forecast period. The segment was valued at\nUSD 1,327.1 million in 2018 and is estimated to reach USD 1,880.9 million by 2024. Fixed-wing drones are equipped with wings as opposed to vertical lift rotors and are similar to conventional airplanes. These drones can be controlled using ailerons, elevators, and rudders, which are integrated into the wings. They can cover long distances, map large areas, and are suitable for long-duration monitoring. The rotary-wing segment is expected to register a CAGR of 8.30% during the forecast period.\nOn the basis of fit, the market has been classified as line-fit and retrofit. The line-fit segment accounted for a larger market share in 2018. Line-fit refers to drone transponders that are installed during the assembly of drones. Line-fit minimizes the work involved post-delivery.\nIn terms of application, the global drone transponder market has been bifurcated into civil and military. The civil segment is anticipated to expand at a higher CAGR during the forecast period. This segment covers the market for drone transponders used for all civilian applications such as in industrial, retail, and government. Civilian drone transponders are crucial for industries such as construction, agriculture, border monitoring, and communication. This, in turn, is driving the growth of the segment.\nBased on drone weight, the market has been categorized as less than 5 kg, 5–25 kg, 25–150 kg, and more than 150 kg. The less than 5 kg segment accounted for the largest market share in 2018. The less than 5 kg drones are small and agile, hard to detect, and easy to control. Thus, the demand for transponders for these drones has been increasing over the last few years.\nRegional Analysis\nBy region, the global drone transponder market has been segmented into North America, Europe, Asia-Pacific, the Middle East & Africa, and Latin America.\nThe market in North America was valued at\nUSD 832.6 million in 2018. The presence of major market players, such as L3Harris Technologies, Inc., Sagetech Corporation, Google LLC, and uAvionix Corporation, is expected to drive the market growth in the region. The North American drone transponder market is anticipated to expand at a CAGR of 5.70% during the forecast period.\nEurope is projected to be the second-largest market during the review period. The regional market is expected to reach\nUSD 672.5 Million by 2024, expanding at a CAGR of 7.22% during the forecast period. Asia-Pacific is projected to be a key region for the market during the review period. The market in the region is expected to reach USD 646.1 million by 2024 at a CAGR of 8.69% during the forecast period. Access Report Details @ https://www.marketresearchfuture.com/reports/drone-transponders-market-7118 Competitive Analysis\nKey players in the global drone transponder market are\n, Inc. (US), Micro Systems, Inc. (US), Microair Avionics Pty Ltd (Australia), Sagetech Corporation (US), Sandia Aerospace Corporation (US), Trig Avionics Limited (UK), and uAvionix Corporation (US). Key Developments In October 2018, Aerobits Sp. z.o.o. collaborated with FLARM Technology Ltd, a company specializing in the production of anti-collision systems for general aviation, to miniaturize its ADS-B devices.", "pred_label": "__label__POS", "pred_score_pos": 0.9827145338058472}
{"content": "Ready, Douglas D., Socioeconomic Disadvantage, School Attendance, and Early Cognitive Development, The Differential Effects of School Exposure, Sociology of Education, October 2010.\nDespite the substantial body of research documenting strong relationships between social class and children’s cognitive abilities, researchers have generally neglected the extent to which school absenteeism exacerbates social class differences in academic development among young children. This study suggests that missing school in the early grades has a more powerful influence on literacy development for low-income students than it does for their more affluent peers. Put another way, school matters more to children from low-income families.", "pred_label": "__label__POS", "pred_score_pos": 0.9341813921928406}
{"content": "Denso Corporation has developed a refrigeration cycle system for passenger vehicles that uses an ejector.\nThe system is used for both an air conditioner and cooler box (vehicle refrigerator) and is installed on Toyota Motor Corporation’s Land Cruiser, launched in Japan in September.\nThis system will also be installed in the Land Cruiser launched in October in North, Central and South America, Asia, and other regions throughout the world.\nThe car air conditioner and cooler box use the same refrigeration cycle. In a conventional refrigeration cycle, a solenoid valve switches between refrigerant flow for cooling in the air conditioner and refrigeration in the cooler box, which effects air conditioning performance when the cooler box is used.\nIn contrast, the new system eliminates the solenoid valve and uses a small refrigerant injector called an ejector instead of an expansion valve, which allows cooling via the car air conditioner and refrigeration through the cooler box simultaneously.\nBy using an ejector that rapidly injects and expands high-pressure refrigerant, the energy that previously was lost in the expansion valve is converted to pressure energy and reused, thus boosting energy efficiency. As a result, high cooling and refrigeration performances are both achieved even when the cooler box is used.", "pred_label": "__label__POS", "pred_score_pos": 0.5795334577560425}
{"content": "WETLAND RESTORATION & ATLANTIC WHITE CEDAR RECOVERY PROJECT\nThe Howard's Branch Wetland Enhancement Project was implemented to comprehend the economic, aesthetic, and environmental benefits of a constructed wetland environment. The project site was a degraded stream bed that had experienced considerable stormwater flow, legacy sediments, and erosion. The deeply incised channel extended approximately 822 linear feet.\nDesign and construction of a curvilinear flow path for the stream and an attendant wetland resulted in a less erosive path for the stream and provided superb habitat for native Atlantic white cedar, cranberry, and low-bush blueberry. These plants not only assist with sediment control, but also help to reduce nitrate and phosphate quantities in stormwater exiting the wetland. This project successfully mimics the historical floodplain function of a braided stream system, which utilizes the entire floodplain to safely pass 100-year storms along the 900 linear feet of the new channel.\nHowards Branch, built in 2001, is considered to be the best example of the restoration that can be achieved when Regenerative Stream Channel (RSC) techniques are fully applied. The planting effort at Howards Branch was listed by the Environmental News Network as the 11th most significant Earth Day project worldwide in 2001. Today the site supports a vibrant, healthy, and sustainable population of the globally threatened Atlantic white cedar. In fact, it is the only known reproducing stand of Atlantic white cedar in the state of Maryland. It also supports a thriving community of fish, including yellow perch.", "pred_label": "__label__POS", "pred_score_pos": 0.6335784196853638}
{"content": "The African political landscape is likely to be dominated by election rhetoric during 2015, with several national, parliamentary and presidential elections due to take place across the continent. At the date of writing, there are no less than 15 elections scheduled for 2015, including; Burkina Faso, Burundi, Central African Republic, Ethiopia, Guinea, Ivory Coast, Lesotho, Mauritius, Nigeria, Somaliland, South Sudan, Sudan, Tanzania, Togo and Zambia.\nSome, including those in Zambia and Tanzania are expected to be relatively peaceful and democratic, despite increasingly assertive opposition parties in both countries. However, in states plagued by violent insurgencies, elections could be catalysts for attacks by groups eager to capture media attention or pursue localised grievances. Elsewhere on the continent, elections could lead to the escalation of simmering ethnic or post-conflict tensions. In particular the elections in Nigeria, the Central African Republic, and both Sudan and South Sudan could encounter serious overarching challenges which could have repercussions for internal and regional stability.\nOne of the major challenges facing African ‘good governance’ is presidents’ adherence to electoral term limitations. In some countries, including Mozambique, Namibia and Ghana, the precedent for adhering to constitutional term limit is cemented in political institutionalism. However, in several others there is an alarming trend towards leaders seeking to extend constitutional term limits; one notable example is the Democratic Republic of Congo (DRC) where talk of changing the constitution to allow Joseph Kabila a third term has sparked civil society and opposition party outrage, resulting in minor protests in major cities. Central Africa in particular is seeing growth in the trend to extend presidential terms, with both Burundi and Rwanda seeking to amend their constitutions.\nIt has long been a dominant narrative that the two term limit placed on presidents in Africa, often in accordance with western norms, does not give leaders enough time to cement change or fully realise policy directives. Former Mozambican President Joaquim Chissano in August 2014 said the two-term model is not ideal for Africa as most leaders leave office before implementing their ideas. In addition, various leaders on the continent have cited the poorly organised and incompetent opposition as a justification for extending their presidential terms, rationalising that an extended term would be in the best interest of the country. The counter argument entails that extending presidential terms in the name of vague national ‘best interests’ in reality sees leaders suppressing any form of opposition or political dissent. A case in point is Burkino Faso, which saw a significant increase in civil unrest and opposition dissent in 2014 that ultimately led to the ousting of long-term President Blaise Compaore.\nSometime after the Arab Spring the spirit of revolution is still in the air, and as such governments have to be cautious in their political rhetoric to avert the escalation of widespread latent discontent into violent unrest or even coup attempts. The election calendar will inevitably yield variable levels of political volatility and countries heading for the polls warrant close scrutiny in pre- and post-election periods. Political and security instability will have rolling repercussions for policy continuity, economic growth and investor confidence\nAfrican Election Timeline – 2015\nJanuary\nBurkina Faso – Presidential\nZambia – Presidential\nFebruary\nNigeria – Legislative and Presidential\nMarch\nTogo – Presidential\nBurundi – Legislative\nApril\nSudan – Legislative and Presidential\nMali – Municipal\nMay\nEthiopia – General\nOctober\nIvory Coast – Presidential\nTanzania – General\nAwaiting date to be announced\nBurkina Faso – Presidential\nGuinea – Presidential\nMauritius – Presidential", "pred_label": "__label__POS", "pred_score_pos": 0.5425382256507874}
{"content": "Missed Opportunities: National Estimates highlights results from a national survey on unaccompanied youth homelessness in America. The study captures youth homelessness broadly, including sleeping on the streets, in shelters, running away, being kicked out, and couch surfing. Overall, findings show one in 10 young adults ages 18-25, and at least one in 30 adolescents ages 13-17, experience some form of homelessness unaccompanied by a parent or guardian over the course of a year. As a nation, we are missing opportunities to ensure that all young people can reach their full potential and contribute to stronger communities and economies across the country.\nSource: Voices of Youth Count", "pred_label": "__label__POS", "pred_score_pos": 0.7332218289375305}
{"content": "Thanks in part to screening technologies like colonoscopy; colon cancer is often detected in its earliest stages. However, the procedure can be expensive and unpleasant. Patients must drink large quantities of laxatives the night before and undergo sedation or anaesthesia during the procedure itself. Current health guidelines in the USA say that adults should have a colonoscopy every ten years beginning at age 50—and sooner or more frequently if other risk factors exist—but US Centers for Disease Control and Prevention (CDC) statistics say that only 65% of American adults actually follow these guidelines. That is why many researchers are searching for less invasive alternatives to the colonoscopy that could induce encourage more people to get tested.\nIn a step towards this goal, researchers from the BC Cancer Agency and the University of British Columbia have identified differences in the blood of people with precancerous polyps compared to people without such polyps. Their results could eventually lead to a cheaper and less invasive initial screening test for colon cancer. The team collected blood plasma samples from three groups of people: 23 who had adenomatous (precancerous) polyps, 21 who had verified colon cancer and 25 healthy volunteers. They mixed each plasma sample with silver nanoparticles and then analysed the mixtures with surface-enhanced Raman spectroscopy (SERS). Their results are published in\nBiomedical Optics Express.\nIn previous work, the team’s collaborators at Fujian Normal University had shown a difference in the Raman spectra of the blood plasma of people with colon cancer compared to individuals who were cancer-free. This new study demonstrated that the test can also be used to identify people with precancerous polyps—a finding that makes it potentially more useful for a screening test, since it may be able to identify cancer risk before the disease actually develops.\nA blood test that could detect precancerous polyps would be an improvement over other non-invasive colon cancer screening mechanisms currently available. For instance, the faecal occult blood test is an at-home kit that looks for evidence of microscopic traces of blood in stool samples, a potential sign of cancer. However, many early-stage colon cancers are asymptomatic and do not bleed, leaving them undetectable by this measure.\nThe initial results are promising, but the procedure is still in the research phase and must go through additional lab tests and clinical trials before actually being implemented. For instance, although the team identified significant spectral differences between the blood samples, they have not yet determined the exact biomolecular sources for these differences. “We are planning new research to identify these responsible molecules,” said Zeng.\nA blood test for colon cancer will never replace colonoscopy: once polyps are identified, a colonoscopy is still the best way to locate them so that they can be removed. However, a blood test could be used as a first line of defence to identify patients with warning signs of cancer; these high-risk patients could then be referred for a colonoscopy for further investigation.", "pred_label": "__label__POS", "pred_score_pos": 0.7233635187149048}
{"content": "New York-based artist and architect\nMichael Wang is not only one of the most interesting artists of our times, but he is also an outstanding expert on the IUCN Red List! His ongoing project, Extinct in the Wild, brings together flora and fauna that are no longer found naturally, but are cultivated and continue to flourish exclusively in captivity. Designated “Extinct in the Wild,” on the IUCN Red List, these homeless species have left nature behind to fully enter the circuits of human culture. Specimens include the axolotl, a fascinating species of Salamander, which can breathe through its skin. Its IUCN Red List status is Critically Endangered. Its extinction is due to urbanization, hunting, invasive species, pollution, climate change and droughts. It now survives solely under artificial conditions in aquariums, in scientific facilities, and in homes as exotic pets. In 2017, Michael Wang gave the axolotl a main role at Fondazione Prada in Milan, where he exhibited his project. Later in 2019, with Extinct in New York, he introduced a series of plants that had been eradicated from New York City’s landscape. During his exhibitions, each included species is displayed within a life-support system tailored to the organism’s unique needs. Exhibition staff are trained to tend these fragile living organisms. Returning curation to its ancient roots in cura, meaning “care,” the curator becomes a caretaker.\nFor the IUCN World Conservation Congress in Marseilles in January 2021, Michael Wang is invited to exhibit his work by Art of Change 21 and the French Office for Biodiversity. He will be focusing on a key location for extinction in the wild for species of plants: South Africa. He (hopefully if he can travel) will document the last known locations of each species in nature as well exhibiting the cultivated species.\nPhoto: Prada Foundation Archive\nFind all the articles from Impact Art News n°18 – April 2020", "pred_label": "__label__POS", "pred_score_pos": 0.5641785860061646}
{"content": "A reliable refrigerator is worth its weight in gold. On top of keeping your food safe to eat, a reliable fridge from a top-notch brand can save you a fortune in costly repairs.\nThe only problem is that finding a dependable fridge is much harder than it sounds. While a high-end refrigerator may be well-made and have all the sophisticated features you want, this is no guarantee that it will stand the test of time.\nOften, it comes down to placing your trust in the reputation of the brand itself. So, which brands make the most reliable refrigerators?\nThat partly depends on the person you're asking. However, these brands have been consistently earned high marks for making reliable refrigerators in 2019.\n1.\nWhirlpool\nWhirlpool has long had a reputation for building reliable home appliances that are engineered to last. While they've been making their signature washing machines for more than 100 years, it's their top-notch refrigerators that are now grabbing headlines.\nPuls, an appliance repair company, surveyed hundreds of repair technicians to gauge the most reliable brands. According to the results, Whirlpool was considered the most reliable brand for refrigerators and the most recommended home appliance brand overall.\nFrom finger-print resistant stainless-steel to sophisticated french door refrigerators, Whirlpool offers a wide selection of refrigerators in various colors and configurations. No matter which fridge style you choose, you can rest easy knowing you've chosen one of the most reliable brands on the market.\n2.\nKitchenAid\nKitchenAid is an American brand that is well-known for making high-quality kitchen appliances-and, no, we're not just referring to the brand's iconic stand mixers that have become revered by chefs and bakers everywhere. In the Puls survey, KitchenAid was recommended as the best choice for refrigerators after Whirlpool.\nKitchenAid is owned by Whirlpool, so it's no surprise that the Puls survey rates this brand so highly for refrigerators. The brand is known for placing emphasis on functionality and attention to detail, which you'll likely pick up on once you start perusing KitchenAid refrigerators and making note of their impressive features.\nSpeaking of features, be sure to check out their innovative five-door configuration fridge. It offers five doors, including two self-closing drawers to optimize organization and freshness!\n3.\nSamsung\nIf tech features are your second priority (after reliability, of course) in a refrigerator, check out Samsung. The Korean-based brand has brought its cutting-edge technology over into the world of refrigeration, and the results are spectacular.\nSamsung is perhaps most notable for its award-winning Family Hub refrigerator, which has taken connected home technology to a new level. With personalized food management and enhanced organization, the Samsung Family Hub has revolutionized how people use their kitchens.\nTo top it off, the Puls survey recommended Samsung just behind Whirlpool and KitchenAid, making it a reliable choice for homeowners. Whether you're getting a Samsung smart fridge or one of its standard models, you can count on unbeatable performance and reliability.\n4.\nLG\nLike Samsung, LG is a tech-savvy brand based in South Korea. Known for its stylish designs and innovative technology, LG was one of the first home appliance brands to export its products to the United States.\nLG offers a vast collection of high-quality refrigerators, including side-by-side, top-freezer, bottom-freezer, door-in-door, and counter depth styles. And, if you're worried about reliability, rest assured that LG was ranked as #1 in product quality and service quality in 2018 American Customer Satisfaction Index ratings\n5.\nGE Appliance\nCutting-edge and modern, GE Appliance has long been one of America's most trusted home appliance brands. Known for combining timeless design with ingenious features, GE Appliance offers a wide collection of refrigerators that are as reliable as they are stylish.\nOne important thing to note is that GE Appliance (GE's appliance division) was sold to Chinese company Haier in 2016. While some initially worried that the acquisition would lead to a decrease in the brand's quality and reliability, no such decline has been noted.\nIn fact, GE Appliances has been doing incredibly well in the last few years and is now quietly working toward becoming America's #1 home appliance brand. From compact refrigerators in black stainless steel to their innovative GE Profile Series with ENERGY STAR ratings, the GE Appliance brand remains a reliable and trustworthy brand in 2019.\nFinal Thoughts\nWhile these brands are noted for their reliable refrigerators, this is still no guarantee that your refrigerator will be long-lasting and hassle-free. It largely depends on how well you take care of your refrigerator and which type of configuration you choose.", "pred_label": "__label__POS", "pred_score_pos": 0.6700023412704468}
{"content": "Food is a fundamental human need. Despite this fact the recent reports of the World Health Organization, provides that approximately 2 million people die due to unsafe food annually. As for this every human being must be awakened about the issue of food safety to ensure that the food on their plate is safe to […]", "pred_label": "__label__POS", "pred_score_pos": 0.9973849058151245}
{"content": "Activation is the bridge between value and ROI.\nAssessing and validating activation of rights on a key property by key property basis is important for ensuring your brand is leveraging the full value from these sponsorships. This practice also enables your brand to better optimize and refine future activations, including the extrapolation of learnings across properties or property types.\nLumency’s approach to activation design is based on a set of tested and proven\nFirst Principles that best leverage a brand’s sponsorship investments and the associated value to drive stronger ROI.\nThe principles ensure activations are holistically planned, taking into consideration brand touchpoints across the connections mix.\nThese principles are used to evaluate and recommend optimization of existing partner activations as part of our scorecarding process.\nLUMENCY’S 8 FIRST PRINCIPLES OF ACTIVATION DESIGN\nConsumer first. Property out front. Brand aligned.\nEnhance the fan experience, don’t interrupt it.\nBe of service to the fan. Address pain points.\nCreate ownable ‘space’— physical, social & digital.\nBe a super fan, demonstrating that the brand believes what fans believe.\nBuild/own relevant and attractive/magnetic content— the brand won’t win if it doesn’t win ‘outside the building/outside the event’.\nThe opportunity audience is the content audience, not the live audience\nProvide a compelling opportunity for the consumer to make the brand part of their story. Don’t force, ask, expect, bribe, or cajole the consumer/fan into becoming part of the brand’s story.\nBuild and deliver omnichannel 360° (210°/140°) activation plans that leverage the sponsorship across multiple consumers/stakeholders—trade, social, digital, mass, CSR, employees, live & regulators.\nOUR ACTIVATION SCORECARD DELIVERS:\nWe evaluate the effectiveness of your brand’s activation across channels including on-site, traditional media, digital, CRM, trade/retail, social, and more.\nWe audit all property sponsor activation efforts to assess which brands are ‘winning’ and in which channels, and to determine where your brand is landing in overall share-of-voice.\nWe identify whitespace within the property’s orbit where your brand can differentiate against other property sponsors in connecting with fans/attendees/followers.\nIncorporating all intel gathered from the activation analysis, competitive overview, and investigation into new opportunities, we provide holistic recommendations for how to optimize activations to be truly best-in-class across all channels.\nThe\n360º Activation Wheel Analysis evaluates brand activation, for your brand and the other brands sponsoring the property and competing with you for share-of-voice, across connections channels.\nBy leveraging Lumency’s Activation Scorecard and First Principles, brands can gain a holistic understanding\nnew strategies and tactics and identifying new opportunities. Looking to understand and improve the effectiveness of your activations?We can help you assess, validate and optimize activations.", "pred_label": "__label__POS", "pred_score_pos": 0.584942638874054}
{"content": "I’ve had cancer. Twice. These are a couple of things I learned:\n1. Someday Jesus and I will be face to face; He is here, with me, right now.\n2. All the ambitions I have, and all the fears I harbour, are insignificant in view of those two facts.\nI learned those lessons as I lay on a cruciform table in an operating room, reflecting as the anesthesia took hold. I could wake up in heaven, I thought. The idea excited me, but it also made me realize I didn’t want to die. There were things I still wanted to do and see, people I wanted to continue to love and some things I needed to set right. But I knew the possibility of dying that day, or in the not too distant future, was very real. The fact that it would happen, some day, was undeniably clear.\nThat made my writer’s heart beat a little faster. There were articles and books I still wanted to write, plays I wanted to see on the stage. The idea of dying in the middle of it all made me squirm a bit on that cold table.\nSo I prayed and that wonderful peace that passes all understanding flooded through me. I realized if I was about to meet Jesus none of my fears and suddenly rather silly ambitions would matter. If He was about to take me home, that meant the purpose for my life, and my work, had been accomplished. If He chose to allow me to continue on this earth, I could trust that he would be there beside me, guiding me all the way. It was a “win, win” situation.\nThen I woke up in an ICU on a respirator with my hands tied down. My first thought was, Well, I don’t think this is heaven. As my brain struggled to register the words the nurse was saying, telling me I had had an allergic reaction to the blue dye they had injected into my body, I tried not to panic. What did that mean, exactly? I was relieved when she told me they were going to remove the tube down my throat and untie my hands. Yes, I thought, that would be very nice.\nThen I saw my husband’s face. Then I had a moment. It was brief, but quite powerful. What if it had been the face of Jesus? I thought of Isaiah’s reaction when he saw the Lord and cried out, “Woe to me, for I am a man of unclean lips” (Isaiah 6:5). Understatement of the century, in relation to myself, I knew. But then there is the rest of the story, in which the angel tells the prophet he has been cleansed and The Lord presents him with his life’s purpose.\nI too have been cleansed and presented with mine. So I will continue to write, to live my life, remembering those two things I learned on that operating table. Until He takes me home.", "pred_label": "__label__POS", "pred_score_pos": 0.5069634914398193}
{"content": "hide\nFree keywords: Face house discrimination task; fMRI; Perceptual decision-making; Task preparation; Left dorsolateral prefrontal cortex\nAbstract: The left dorsolateral prefrontal cortex (ldlPFC) has been highlighted as a key actor in human perceptual decision-making (PDM): It is theorized to support decision-formation independently of stimulus type or motor response. PDM studies however generally confound stimulus onset and task onset; when the to-be-recognized stimulus is presented, subjects know that a stimulus is shown and can set up processing resources—even when they do not know which stimulus is shown. We hypothesized that the ldlPFC might be involved in task preparation rather than decision-formation. To test this, we asked participants to report whether sequences of noisy images contained a face or a house within an experimental design that decorrelates stimulus and task onset. Decision-related processes should yield a sustained response during the task, whereas preparation-related areas should yield transient responses at its beginning. The results show that the brain activation pattern at task onset is strikingly similar to that observed in previous PDM studies. In particular, they contradict the idea that ldlPFC forms an abstract decision and suggest instead that its activation reflects preparation for the upcoming task. We further investigated the role of the fusiform face areas and parahippocampal place areas which are thought to be face and house detectors, respectively, that feed their signals to higher-level decision areas. The response patterns within these areas suggest that this interpretation is unlikely and that the decisions about the presence of a face or a house in a noisy image might instead already be computed within these areas without requiring higher-order areas.", "pred_label": "__label__POS", "pred_score_pos": 0.8077924847602844}
{"content": "7. Damaged or broken shaft\nAppearance: The shaft is bent or broken. A clean break indicates an “instantaneous” fracture caused by sudden overload or imbalance. If the broken shaft is discoloured (usually blue), the damage was gradual, indicating excessive heat build-up before the shaft broke.\nCause: A misaligned belt causes excessive wear. An over-tensioned belt imposes a powerful bending force on the shaft resulting in shaft bending or early shaft fracture. Excessive vibrations due to lack of maintenance.\nSolution: Replace the water pump and make sure to inspect the belt drive system: belt, tensioner, pulleys, belt tension and alignment. If equipped with a water pump mounted fan, inspect the fan/fan clutch assembly. The fan may not be squarely mounted on the shaft. A bent or damaged fan, a worn spacer, or a worn or damaged fan clutch could also be factors contributing to the break.", "pred_label": "__label__POS", "pred_score_pos": 0.9989742040634155}
{"content": "The U.S. Department of Energy (DOE) today announced $3.25 million for the American-Made Geothermal Manufacturing Prize (Geothermal Prize). A first of its kind for geothermal technology, this prize is designed to spur innovation and address manufacturing challenges fundamental to operating in harsh geothermal environments.\nDepartment of Energy\nThe Department of Energy (DOE) mission is to ensure America’s security and prosperity by addressing its energy, environmental, and nuclear challenges through transformative science and technology solutions. This includes catalyzing the timely, material and efficient transformation of the nation’s energy system and securing U.S. leadership in advanced manufacturing technologies, as well as, maintaining a vibrant U.S. effort in science and engineering as a cornerstone of our economic prosperity. To accomplish these goals, the DOE has established multiple manufacturing initiatives as cross-cutting innovative programs within the department to strengthen U.S. manufacturing competitiveness and to increase U.S. manufacturing competitiveness across the board by boosting energy productivity and leveraging low-cost domestic energy resources and feedstocks.\nAdvanced manufacturing involves the minimization of the energy of the production, use, and disposal of manufactured goods, which range from fundamental commodities such as metals and chemicals to sophisticated final-use products such as automobiles and wind turbine blades. The manufacturing sector, a subset of the industrial sector, consumes 25 exajoules (24 quads) of primary energy annually in the United States — about 79% of total industrial energy use. The DOE partners with private and public stakeholders to support the research and development of innovative technologies that can improve U.S. competitiveness, save energy, and ensure global leadership in advanced manufacturing technologies.\nThe DOE uses manufacturing innovation institutes to develop advanced manufacturing technologies to support these initiatives. At the end of the fiscal year 2016, the DOE has awarded two institutes. The first, PowerAmerica, is focused on wide bandgap semiconductor technologies for next generation power electronics. The second, the Institute for Advanced Composites Manufacturing Innovation, is focused on composite technologies for vehicles, wind turbine blades, and compressed gas storage tanks. Since the beginning of the latest fiscal year, i.e. FY 2017, three additional institutes have been solicited, selected and awarded. These additional institutes include; Smart Manufacturing: Advanced Sensors, Controls, Platforms and Modelling for Manufacturing, Process Intensification: Rapid Advancement in Process Intensification Deployment (RAPID) and Reducing Embodied Energy and Decreasing Emission (REMADE) in Materials Manufacturing.\nEnergy Department Selects Four Projects for High Performance Computing for Manufacturing in Steel and Aluminum Production\nThe U.S. Department of Energy (DOE), in partnership with Lawrence Livermore National Laboratory (LLNL), announced nearly $1.2 million for four new projects to support American steel and aluminum manufacturers in improving energy efficiency, increasing productivity, and accelerating manufacturing innovation.\nThe High Performance Computing for Manufacturing (HPC4Mfg) Program, designed to spur the use of national lab supercomputing resources and expertise to advance innovation in energy-efficient manufacturing, is seeking concept papers for a fourth solicitation. Concept proposals from U.S.", "pred_label": "__label__POS", "pred_score_pos": 0.5259033441543579}
{"content": "As we age there is a predictable decline in our immune function. Compromised immunity begins in early adulthood and accelerates rapidly after 40 years of age. Scientist call this Immunosenescence. Immunosenescence explains why older people are at greater risk of infections and diseases. As we age, our immune system does not respond as robustly to allergens and other challenges.\nA recent study from England suggests that we can slow the loss of immune function that comes with aging. The investigators analyzed immune function in individuals 55-79 years old who had maintained a high level of physical activity for much of their adult life and compared this to an age group match of healthy individuals who were not involved in regular exercise, the sedentary group. The researchers measured multiple biological markers of immune competence in both groups. They found older adults who consistently exercised throughout their life had a stronger and better functioning immune system compared to the sedentary adults. Surprisingly the researchers found that some of the markers of immune function in the master athletes (55-79) compared favorably with the levels found in healthy young individuals aged 20-36. The bottom line – physical inactivity may be a profound driver for age associated loss of immune function.", "pred_label": "__label__POS", "pred_score_pos": 0.7273274660110474}
{"content": "Select a SchoolSchool of Design Select a ProgrammeDesign Products Select a StudentKenny Arnold Kenny Arnold Major project: Anthropocene Organisms: The Waterside Gobbler The Waterside Gobbler\n(Rubbish Eatus Rex)\nWhether intentional or accidental, discarded single use plastic items frequently enter the ecosystem via the waterways of cities with canals. Once in the water, these items flow along towards natural gathering points in certain areas, where they are ripe for collection. However while they remain in the water, birds, fish, and other animals mistake the pollution for food. In response to the problem, new activities, such as plastic fishing, have emerged to encourage citizens to take action, become informed, and shift their behaviour towards a more sustainable lifestyle.\nDuring this period of change, a hybrid life form has emerged. Half bin, half creature,\nWaterside Gobblerslive near the water and seek to pick out and collect passing plastic debris with the aid of a helpful human.\nGobblers like to adapt to their neighbourhoods with colour and form to promote a sense of locality. They seek to encourage city dwellers who visit the waterside to take action about cleaning their environment; educate the wider public about the impact that pollution has on the ecosytems we are part of, and encourage thoughtful actions that benefit all species.\nSchool\nSchool of Design\nProgramme\nMA Design Products\nContact\nI like to use play as a design approach for exploring possibilities that can promote positive change in society.\nMuch of my work is centered around sustainability and social engagement. Projects I have worked on during my time at the Royal College of Art have explored a wide range of topics including – our relationship with the environment, the future of food, tools to promote creative thinking, the circular economy, and engaging people through play. I prefer a hands on approach in my practice, and I enjoy thinking through making. Previous degrees BFA, Industrial Design, University of Michigan, Ann Arbor, USA, 2011 Experiences Associate researcher, Brand Genetics, London, 2018–present; Industrial designer, KA Design, London, 2011–present; Design instructor, Publicolor, New York, 2015–2016; Toy inventor, JMP Creative, Santa Ana, USA, 2015; Innovation intern, Fahrenheit 212, New York, 2014; Toy designer, Techno Source, New York, 2012–2013 Exhibitions Milan Design Fair, 2019 Awards Circular Case Award, 2017", "pred_label": "__label__POS", "pred_score_pos": 0.6422313451766968}
{"content": "For a company strategy to be effective, your employees need to be aware of it. This ensures everyone is aligned with the same goals, focusing their efforts appropriately to make reaching critical objectives possible and shaping a portion of the organization’s culture. To make sure that all employees are on the same page, communication is vital.\nCommunicating Company Strategy to Your Team\nEffective communication often features specific hallmarks. By focusing on the facets of strong communication, you increase the odds that your message will be genuinely received. Here are three tips to get started.\nRelated Content: Your Company Success Depends on Effective Employee Communication 1. Focus on Clarity\nFor a strategy to be communicated effectively, it needs to be clearly defined. Employees should be able to easily see how it aligns with the company’s mission, vision, and core values, as well as how they can play a role in implementing the strategy. If the points are too ambiguous or do not seem to coincide with larger goals, confusion is inevitable. Take the time to truly hash out what the new strategy means in advance and then strive to articulate it in a manner that is digestible by the masses.\n2. Never Underestimate Engagement\nIn many cases, a company’s strategy is a dry subject. Often, it involves highly technical concepts, so it is not going to be a naturally exciting topic for many of your employees. However, if you deliver the message in an engaging way, you can improve how the information is received.\nWhen you discuss the company strategy, try to find a way to make the information enticing. Often, this means going beyond standard communication methods, like email, and embracing options that are more stimulating, such as images and video.\nSimilarly, giving employees a chance to chime in on the topic can increase engagement, particularly if you frame it as an invitation for open dialog. This allows them to get involved more directly. Plus, it creates an opportunity for questions to be asked, enabling those who need more clarity a method for getting what they require.\n3. Utilize a Reinforcement Cycle\nAfter the initial message is delivered, there is still more work to be done. Reinforcing the concept repeatedly ensures that the company strategy remains at the forefront of everyone’s mind, making it a critical step in the communication process. Work various points into a variety of paradigms, such as company meetings, newsletters, or social media posts. Over time, this helps ingrain the strategy into your culture.\nAre You Looking for Top Talent to Fill Your Open Positions?\nThe professionals at RealStreet pride themselves on being experts on the unique needs of the architecture, engineering, and construction industries, allowing us to locate exception talent for every business that partners with us. We aim to put the “source” in human resources, ensuring you have access to a reliable partner for your hiring needs. If you are seeking exceptional architecture, engineering, or construction professionals for your open jobs, experience the RealStreet difference today. Contact us to speak with one of our experienced professionals and see how our range of services can help you find the right candidates quickly and efficiently.", "pred_label": "__label__POS", "pred_score_pos": 0.8430528044700623}
{"content": "Potato chips are a common trigger food for many people who are trying to lose weight. In this video, Dr. Oz shares a guilt-free alternative that's much healthier for you but just as tasty.\nContinue Learning about Eating Habits and Nutrition\nImportant: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.", "pred_label": "__label__POS", "pred_score_pos": 0.7593199014663696}
{"content": "After receiving backlash due to their initial algorithm, the government has made a surprising u-turn with students’ A-Level results.\nThe government has announced that students will expect to receive different results due to a new method of grading. Initially, students were graded alongside an algorithm that took past students and their area into account, but this received backlash due to it being a hindrance for some, especially those who live in low-income areas. This led to some people receiving unfairly downgraded results, as well as being rejected from their first choice universities.\nHowever, this sudden change that Education Secretary Gavin Williamson announced has meant that A-Level students will instead receive a teacher-assessed grade. This has been welcomed by some, as it is believed that this is the most accurate prediction of their performance. However, others have found that they are scrambling to find a place for their preferred universities, due to their grades either increasing or decreasing. For instance, the University of Oxford has noted ‘\nsignificant capacity constraints’, with an increase in students receiving the required grades for their preferred universities. The amount of worry has been amplified, due to students not meeting the expected grades with the initial algorithm, but now meeting the requirements through their newly received predicted grades. This has caused pressure on universities to find spaces, both on the courses and in accommodation.\nThe lack of space in universities is emphasised by Durham University offering students money to defer their offers to 2021. With a guarantee of a bursary and accommodation, the university is aiming to relieve pressure on their services for the upcoming academic year.\nWhen speaking on this shift from the initial algorithm to using predicted grades for A-Level results, Gavin Williamson stated how he ‘\nnow believe[s]it is better’, as well as noting how his ‘ focus is making sure youngsters get the grades that they deserve.’\nWessex Scene contacted the University of Southampton admissions team for their take on the recent news. In an automated reply they stated the following:\n‘\nIf your reissued A level grades meet or exceed the conditions of your offer, then we will confirm your place at the University of Southampton for September 2020 entry.’ […] ‘In a few cases, where courses have very strict capacity constraints, including Medicine, we may have to ask you to defer your place until September 2021.’ […] ‘If your reissued grades are marginally below the conditions of your offer, we may be unable to confirm your place until September 2021. If there were non-academic conditions attached to your offer, we would expect you to meet them by 7 September 2020.’ […] ‘In a small number of cases, the course you applied for in 2020 may not be running in 2021. In this case, we will not be able to offer you a guarantee of an offer but would encourage you to speak to the admissions team to discuss your options.’", "pred_label": "__label__POS", "pred_score_pos": 0.9995845556259155}
{"content": "Navigate A & S\n< >\nA children’s psychology lab at UNC Greensboro is seeking participants aged 5 to 10 to join two virtual studies.\nThe projects focus on children’s perceptions of people who are smart, wealthy or powerful, and are conducted by doctoral students in UNCG’s Development and Understanding of Children’s Knowledge (DUCK) Lab.\nThese projects provide fun, safe activities for children, help deepen the researchers’ understanding of social and cognitive development, and are critical training elements for doctoral students completing their degrees.\nAll projects have shifted online during the COVID-19 pandemic. These include:\nProject 1:PhD candidate Kimmy Marble, supervised by Dr. Janet Boseovski, is leading a study focused on children aged 5 to 8. She is interested in whether children expect smart or wealthy people to assist others, a concept known as prosocial behavior. Do children think these people are more accountable to help someone in need relative to other adults?\nChildren who participate in this study will listen to stories via screen share and respond to a few questions about the story characters. The study is interested in whether children’s responses indicate that they associate knowledge and wealth with power and how this view might impact children’s perceptions of adults’ morality and trustworthiness.\nProject 2:PhD candidate Andrea Yuly, supervised by Dr. Janet Boseovski, is using a story-telling method to investigate 5- to 10-year-olds’ understanding of social rank. What kind of information is relevant for obtaining respect, admiration, and value in the eyes of others? This study will examine whether children distinguish between prestige-based status and social rank that is derived from control over others.", "pred_label": "__label__POS", "pred_score_pos": 0.7774137258529663}
{"content": "Raddeanin A suppresses lung cancer cell proliferation via induction of apoptosis and increased production of ROS Abstract\nAt present, in vitro cell experiments have confirmed that RaddeaninA can effectively inhibit the proliferation of some tumor cells, but the effect of RaddeaninA on lung cancer cells has not been observed. Therefore, this study explored its effect on lung cancer cells and its mechanism of action. Human lung cancer cell lines were treated with serum-free medium and varied concentrations of Raddeanin A. Cell proliferation and apoptosis were determined using MTT, and flow cytometric assays, respectively. The intracellular level of ROS was determined using DCFH-DA assay. Protein and mRNA expressions of bax, bcl-2 and cyt c were measured using Western blotting and qRT-PCR. RaddeaninA treatment can promote PC-9 cell apoptosis in a time and dose-dependent manner (p<0.05). Treatment of PC-9 cells with Raddeanin significantly and dose-dependently increased the activities of caspase-9 and caspase-3 (p<0.05), and led to significant and dose-dependent increases in ROS levels (p<0.05). Treatment of PC-9 cells with Raddeanin A led to significant and dose-dependent decreases in mitochondrial membrane potential (p<0.05). It significantly and dose-dependently upregulated bax mRNA and protein expressions, but down-regulated bcl-2 mRNA and protein expressions significantly and dose-dependently (p<0.05). On the other hand, Raddeanin significantly and dose-dependently down-regulated cytoplasmic bax protein expression, while upregulating cyt c expression (p<0.05). Similarly, bax protein expression was significantly and dose-dependently upregulated in mitochondria, but the corresponding cyt c expression was significantly and dose-dependently down-regulated (p<0.05). Raddeanin A is a potential and effective lung cancer chemotherapy drug, which can induce lung cancer cell apoptosis and inhibit proliferation.\nKeywords\nLung cancer; Proliferation; Apoptosis; Raddeanin A.", "pred_label": "__label__POS", "pred_score_pos": 0.9973052144050598}
{"content": "Three of the most heavily invested players in the pharmaceutical industry are at odds.\nPharmaceutical manufacturers have to recoup R&D costs and demonstrate accountability to their leadership and shareholders.\nPBMs are responsible for driving down costs for their plan sponsors. Frequently, this is achieved by hard negotiations with manufacturers.\nPharmacists, the healthcare providers best positioned to influence patient outcomes and maximize the value delivered by high-cost medication therapies, are often afterthoughts to the conversation on healthcare cost reduction.\nWhat is the secret to reduce healthcare costs, align strategic objectives, and delivering healthcare value? Refocus on the core concept that patients who are adherent to their medication regimens are healthier, less costly and help players in all three categories achieve their core objectives.\nPharmacists are already in the prime position to facilitate this exercise in placing the patient at the center. Read why and understand steps that can be taken today to align the patient care business in this recent Drug Topics article by Curant COO, Marc O’Connor.", "pred_label": "__label__POS", "pred_score_pos": 0.5280716419219971}
{"content": "This discussion forum offers an opportunity to discuss the transformational changes needed to develop over-arching frameworks such as agro-ecosystems that integrate landscape level approaches for both forest and farm livelihoods and food security. The forum will explore how current landscape management and restoration efforts could be expanded to include opportunities for maintaining, enhancing and restoring the sustainable productivity of crop and range lands, integrated with current efforts focused on forest ecosystems. Food producers, family farmers, forest and farm producer organizations, and indigenous peoples are already key actors and potentially major drivers of this integrated approach to sustainable landscape management. This requires better engagement with these producer groups, especially with agriculture and other relevant ministries, and establishing actual cross-sectoral collaboration and coordination mechanisms to make things happen. Even achieving the significant targets for forest restoration may also be more likely when combined with this perspective. Using an agro-ecosystems lens involves maintaining intact landscapes, improving management practices and technology to increase productivity and avoid degradation, and applying a more integrated approach when restoration is needed. This integrated approach enhances the possibility of transformational change for food systems, climate resilience and the SDGs.\nIn the months preceding the GLF, participating organizations and individuals will connect, share, learn and act around five themes:\nEvents\nView the action-packed calendar of GLF online and in-person gatherings, as well as those of our partners.\nCommunity\nConnect, share, learn, act. Search jobs, join community groups, post an event, or share an article with our community.", "pred_label": "__label__POS", "pred_score_pos": 0.9164717793464661}
{"content": "A global shortage of condoms is looming, the world’s biggest producer said, after a coronavirus lockdown forced it to shut down production.\nMalaysia’s Karex Bhd makes one in every five condoms globally. It has not produced a single condom from its three Malaysian factories for more than a week due to a lockdown imposed by the government to halt the spread of the virus.\nThat’s already a shortfall of 100 million condoms, normally marketed internationally by brands such as Durex, supplied to state healthcare systems such as Britain’s NHS or distributed by aid programmes such as the UN Population Fund.\nThe company was given permission to restart production on Friday, but with only 50% of its workforce, under a special exemption for critical industries.\n“It will take time to jumpstart factories and we will struggle to keep up with demand at half capacity,” Chief Executive Goh Miah Kiat told Reuters.\n“We are going to see a global shortage of condoms everywhere, which is going to be scary,” he said.\nMalaysia is Southeast Asia’s worst affected country, with 2,161 coronavirus infections and 26 deaths. The lockdown is due to remain in place at least until April 14.", "pred_label": "__label__POS", "pred_score_pos": 0.7743631601333618}
{"content": "Hoenig M. and Ferguson D.C.\nIntravenous glucose tolerance tests were performed in eight adult cats before and after a 4-week treatment with thyroxine. The untreated cats had a mean fasting blood glucose concentration of 7.7 +/- 0.3 mmol/l and a mean fasting insulin concentration of 88 +/- 31 pmol/l which were not significantly different from mean fasting glucose and insulin concentrations after 4 weeks of thyroxine administration (6.9 +/- 0.2 mmol/l and 101 +/- 28 pmol/l respectively). At 120 min after glucose injection, the glucose concentration in untreated cats returned to baseline concentrations as did the insulin concentration. However, in the hyperthyroid cats both glucose and insulin concentrations were significantly (P less than 0.001) higher (13.6 +/- 0.8 mmol/l and 245 +/- 17 pmol/l respectively) in comparison with the baseline and untreated cats. The t1/2 for glucose disappearance was significantly higher in the cats rendered hyperthyroid, and the glucose disposal rate constant (K) was significantly lower in this group. It is concluded that hyperthyroidism in cats leads to impairment of glucose tolerance possibly due to peripheral insulin resistance.", "pred_label": "__label__POS", "pred_score_pos": 0.9957616925239563}
{"content": "Abstract Purpose\nTeacher education in many countries is under reform with growing differences in its form and function. This is indicative of the ongoing negotiations around the place of theory, research and practice in teachers’ professional learning. However, the demand for mentoring of trainee teachers during often extended and multiple school-based placements is a relative constant. Indeed, with the trend towards greater school-based professional experience mentoring practices become ever more critical. The paper aims to discuss this issue.\nDesign/methodology/approach\nThis is a conceptual paper written from the perspective of an experienced teacher educator in England, drawing on both practical experience and a body of associated research. It can be conceptualised as related to cases of practice, linked to episodes of practitioner research grounded in the ethics of the improvability of practice, the desire to meet the needs of the professional communities and a deep understanding of the demands and cultures of their workplaces.\nFindings\nMentoring can be re-imagined as a dynamic hub within a practice development-led model for individual professional learning and institutional growth. Acting on this conceptualisation would allow mentors, trainees and other supporting teacher educators to contribute to the transformation of professional learning practices and educational contexts.\nOriginality/value\nThis paper goes beyond offering merely helpful guidance to participants and stakeholders in mentoring, or stipulating standards to be achieved, to considering what might be described as a hopeful or transformational stance in relation to mentoring. Teacher educators can continue to bring value to the transformation of teacher education through a focus on mentoring as an educative process.\nKeywords Citation\nLofthouse, R.M. (2018), \"Re-imagining mentoring as a dynamic hub in the transformation of initial teacher education: The role of mentors and teacher educators\",\nInternational Journal of Mentoring and Coaching in Education, Vol. 7 No. 3, pp. 248-260. https://doi.org/10.1108/IJMCE-04-2017-0033 Publisher:\nEmerald Publishing Limited\nCopyright © 2018, Emerald Publishing Limited", "pred_label": "__label__POS", "pred_score_pos": 0.9491186141967773}
{"content": "Guardianships can help families plan for the care of disabled and aging loved ones who have become incapacitated. A guardianship is a legal tool that allows one person to make decisions for another person.\nThe guardian is able to make important personal, financial and healthcare decisions for the the disabled or incapacitated individual referred to as a ward. Typically, the guardian must be 18 years of age or older. If the guardian is named by the ward as a trusted individual to care for their financial and medical affairs in circumstances of incapacity, then they will generally be appointed by the court. If the ward has not expressed their wishes for a guardian, the court will examine documents that may express their wishes for a guardian.\nIt is helpful to be familiar with the laws for appointing a guardian in the state where the ward lives. The powers of the guardian typically include ensuring the availability of care for the ward; making financial decisions for the ward; making medical decisions for the ward; ensuring the educational and medical services for the ward are maintained and adequate; and updating the court concerning the ward’s condition.\nAll of the powers of a guardian are important which is why it is beneficial to understand how guardianships work when a loved one has become incapacitated or is disabled and how a guardianship can help in those situations. Guardianships can be a valuable part of the overall estate planning process that estate planners and families should be familiar with.", "pred_label": "__label__POS", "pred_score_pos": 0.7229148149490356}
{"content": "Abstract\nKinesin translocation is thought to occur by a conformational change in a region of the motor domain called the neck linker. However, most evidence supporting this hypothesis comes from monomeric constructs unable to move processively. To address this issue, we investigated the neck-linker configuration on microtubule-bound monomeric and dimeric kinesin constructs using single-molecule fluorescence polarization microscopy. We found that the neck-linker region (i) is very mobile in the absence of nucleotides and during steady walking, (ii) decreases mobility and aligns along the microtubule axis in the presence of AMPPNP or ADP+AlF\n- 4, (iii) is mostly ordered in the monomeric constructs in the presence of ADP+AlF - 4, and (iv) is closer to parallel to the microtubule axis in the dimeric constructs. These results support the proposed role of the neck linker and suggest a coordination mechanism between the two motor domains in the dimer. ASJC Scopus subject areas Structural Biology Molecular Biology", "pred_label": "__label__POS", "pred_score_pos": 0.5693166851997375}
{"content": "Teachers play a leading role in the students’ development in school. For instance, they assist students in developing independent critical thinking skills and become more advanced. They do this by aiding them in discovering their skills and certain abilities, as well as...\n24 September, 2020 in Writing an EssayContinue reading", "pred_label": "__label__POS", "pred_score_pos": 0.9991381764411926}
{"content": "Articles for the World Space Week Call for Contributions is now CLOSED!\nDeadline: 23 September, 2020\nIn 1999, the UN General Assembly declared 4 to 10 October “World Space Week” to highlight the contributions of space, science, and technology to the betterment of the human condition. Since then, space has become a crucial factor in enabling a more sustainable future for Europe. In 2019, the EU focused on using our understanding of outer space to find solutions to climate change, create sustainable ecosystems and Arctic environments, and encourage the next generations to explore our solar system.\nThe theme this year is “Satellites Improve Life”, which focuses on the impact of satellites in our daily lives. To mark this occasion, the European Student Think Tank welcomes articles investigating correlations between the European Union and Space.\nWe suggest the following\ntopics to explore: The EU’s space sector and space policy The EU and Space & Satellites technology Role of EU youths in space research and applications EU Academia and Industry initiatives related to Space Any other relevant topic\nSuggested length of contributions: 500 to 1000 words. You are encouraged to follow our writing format.\nSend your submission to editorinchief@esthinktank.com by 23rd September 2020.\nDo not hesitate to contact us for any further inquiries!", "pred_label": "__label__POS", "pred_score_pos": 0.6732949018478394}
{"content": "One drink is equivalent to: Beer: 12 fluid ounces milliliters Wine: 5 fluid ounces milliliters Distilled spirits 80 proof : 1. This effect can include nearly all zero calorie sweeteners, including stevia. During the fasting state the energy is taken from deposits and the fat burning hormones tend to go up. However, black coffee, calorie-free sweeteners, diet soda and sugar-free gum are permitted. It contains caffeine, which increases alertness and helps curb appetite. Autumn Elle Nutrition. But adding in sugar, cream, or milk is best avoided, as it can add calories to the drink that can take you out of a fasted state.\nYou might be surprised how much of an impact a “calorie-free” drink has on halting your weight loss progress. Stevia is a zero-calorie sweetener. However, artificial sweeteners in diet soda can trigger sugar cravings. HGH is known for its burning fat, building muscle, improving skin texture. We explore how. Thus, fasting can potentially delay aging and can hamper diseases while minimizing the struggles of intense dietary interventions. These benefits can be quickly canceled out if you consume too many liquid calories during a period of what should be a fasted state.\nUpdated: Oct 8. Affiliate Disclosure. Diet soda typically contains zero calories, so does that mean you can have it during your fast and still achieve your weight loss and wellness goals? Not necessarily. Today I’m breaking down the deets of diet soda and Intermittent Fasting! Diet soda is the soda industry’s answer to sugar. Instead of using the typical sweeteners such as sucrose table sugar or high fructose corn syrup – both of which contain calories – they opt for the no-calorie options. These sweeteners include acesulfame potassium and aspartame. You may even see more natural ingredients to this zero calorie approach with options like stevia and monk fruit.", "pred_label": "__label__POS", "pred_score_pos": 0.6720455884933472}
{"content": "Article summary\nPrevious studies have pointed the need for more research, which explores how peer provision brings about change associated with recovery. This study aims to test Leamy’s framework, which consists of five recovery processes: connectedness, hope, identity, meaning and empowerment (also known as the CHIME framework) within the peer provision context.\nBy Grace Zeng, Donna Chung\nThe Journal of Mental Health Training, Education and Practice", "pred_label": "__label__POS", "pred_score_pos": 0.9967737197875977}
{"content": "Neocallimastix californiae G1 is an isolatedstrain of anaerobic gut fungi from the phylumNeocallimastigomycota, the earliest diverging branch of free-livingfungi. Members of this class are obligate anaerobes, lackmitochondria (harboring hydrogenosomes instead), and reproduceasexually through the production of flagellated zoospores. Theirlife cycle resembles that of the members of the Chytridiomycotaphylum. Gut fungi (Neocallimastigomycetes) are members of the gutmicrobial community within large herbivores, such as ruminants andhindgut fermenters, where they are the primary microbes to colonizeplant material and initiate its degradation. Gut fungi can beisolated from the feces of these animals and sustained in anaerobiclab cultures where they are capable of degrading biomass withoutpretreatment (Haitjema et al., 2014), and are of key biotechnologyinterest due to the biomass-degrading enzymes that theyproduce. Neocallimastix californiae G1 was isolated fromthe feces of a goat at the SantaBarabara Zoo. This fungal isolate is of particular interest forboth fungal evolutionary and application based studies. The genomewill aid in the discovery of novel biomass degrading enzymes thatmay be engineered or heterologously expressed for the production oflignocellulosic biofuels and other value added chemicals.Furthermore, the genomes will enable future –OMICs basedcharacterization of these organisms, including insight into theirunique organelles and biomass-degrading enzyme complexes. References Haitjema CH, Solomon KV, Henske JK, Theodorou MK, O’Malley MA. 2014. Anaerobic gut fungi: Advances in isolation, culture, and cellulolytic enzyme discovery for biofuel production. Biotechnol. Bioeng. 111:1471–1482.", "pred_label": "__label__POS", "pred_score_pos": 0.6121227741241455}
{"content": "When I was a kid, my grandparents used to take me to the state’s fish hatchery in New Gloucester, Maine to look at the fish. Even though they took me several times, I never tired of watching the brown trout swim in schools from pool to pool. Later when I was a teen-ager, I belonged to the Water Quality Monitoring Team in high school. My teammates and I sampled water from area lakes and ponds, including Damariscotta Lake, where I had fished for brown trout with my brother and grandfather years before. I loved to cast and once caught two fish on the same hook! This made my younger brother envious. I should take up fly-fishing again.\nTrouts Unlimited started a program for school kids called Trout in the Classroom over 20 years ago. Students in grades K-12 get to raise trout from eggs to fry in a classroom tank; monitor the tank water quality; engage in a stream habitat study; learn to appreciate water resources; begin to foster a conservation ethic; and grow to understand ecosystems. Each program is unique depending on the school’s curriculum. At the end of the year, students release the trout into a nearby stream that has been approved by the state.http://www.troutintheclassroom.org/home This program is run in 20 states so far. For state-specific resources, visit:http://www.troutintheclassroom.org/teachers/\nstate-specific-resources There are many opportunities for local residents outside the school to volunteer with the Trout in the Classroom program:http://www.troutintheclassroom.org/volunteers", "pred_label": "__label__POS", "pred_score_pos": 0.7888855934143066}
{"content": "Abstract\nFurther analysis has revealed that the signal reported in Extended Data Fig. 1c of this Letter is attributed to phosphorylethanolamine, not carbamoyl phosphate. A newly developed derivatization method revealed that the level of carbamoyl phosphate in these NSCLC extracts is below the detection threshold of approximately 10 nanomoles. These findings do not alter the overall conclusions of the Letter; see associated Amendment for full details. The Letter has not been corrected online.\nASJC Scopus subject areas General", "pred_label": "__label__POS", "pred_score_pos": 0.9900091886520386}
{"content": "North America: New NSF protocol published\nNSF International has published a new protocol as part of its commitment to improve building water health:\nNSF P453: Cooling Towers – Treatment, Operation, and Maintenance to Prevent Legionellosis. This protocol outlines proper maintenance and safety practices associated with evaporative cooling systems. It also addresses health concerns associated with commercial buildings, including healthcare facilities, whose residents may experience health issues, such as Legionellosis from improperly maintained water systems. The new protocol uses the water safety plan approach recommended by the World Health Organization (WHO) to assemble a team, identify potential hazards and establish control measures to prevent the growth of Legionella bacteria. The protocol can be used by facilities to establish a management plan for the treatment, operation and maintenance of cooling-tower water systems.", "pred_label": "__label__POS", "pred_score_pos": 0.9839644432067871}
{"content": "While Medicare Advantage (MA) plans have new flexibility to target and cover supplemental benefits that address health-related social needs, few plans provided these types of benefits in 2019. Multiple factors may impede the ability of plans to comprehensively address these social needs.\nMA plan representatives cited multiple factors that may limit the expansion of these supplemental benefits. First, insurers must rely on limited and varied funding from plan rebates to cover these benefits. These supplemental benefits are funded by rebates for MA plans that bid below the county-level benchmark set by the Centers for Medicare & Medicaid Services (CMS), and rebates averaged $107 per member for month across all MA plans with wide variation across states and counties.\nAdditionally, MA plan representatives perceived challenges in key areas, including contracting with community-based organizations, identifying benefits with a potential return on investment, and dedicating resources to new types of benefits such as housing supports. Since available benefits will vary based on county as well as by enrollee health conditions, plans anticipate challenges with enrollee communication and marketing. Plan representatives suggested opportunities to improve benefit flexibility policies, including the provision of additional funding from CMS to MA plans.\nWhat resources can Medicare Advantage plans use to address enrollees’ health-related social needs? How are Medicare Advantage plans making decisions around new flexibilities for benefits to address health-related social needs?", "pred_label": "__label__POS", "pred_score_pos": 0.9419488906860352}
{"content": "If you own a pool, you know the challenges and rewards of maintaining it year round. Why limit the beauty of your pool only to the daytime? Lighting your pool not only highlights this beautiful feature, but adds security by brightening the area to protect children and guests that may be unfamiliar with your yard.\nA lighting professional will be able to showcase the strong points of your pool, whether this is in the water or in the architecture around it. A warm, well placed beam can exhibit a waterfall or hot tub, transforming a backyard space by drawing attention to its beauty and serenity. Or if your yard is often the backdrop of a party, you can opt for modern, upbeat lighting that highlights your pool in fun colors!\nPool lighting is also a security measure. You can never be too careful with children around water – a lit pool will help them avoid falling in. It will protect your guests by adding a gentle glow to outline your pool and help them navigate your yard and avoid falling in. Lighting the features around your pool will also deter burglars by eradicating dark places for them to take cover.\nDFW Pool Lighting\nIf you are ready to explore pool lighting and other lights for your outdoor property, call us today at 817-345-3696!", "pred_label": "__label__POS", "pred_score_pos": 0.7263907790184021}
{"content": "Defensible, Strategic and Informed Pricing – Deliver on Transparency and Grow Your Margin\nAlmost weekly, the news features healthcare pricing in a negative light. While these stories are often twisted into attention-grabbing headlines, healthcare leaders are still left to wonder if their pricing is as accessible, defensible and strategic as it could be.\nTo read more about the challenges facing healthcare organizations, including CMS requirements and heightened consumerism, download this Strategic Pricing Whitepaper.\nFill out this form to download the whitepaper:", "pred_label": "__label__POS", "pred_score_pos": 0.9972646236419678}
{"content": "Articles\n1 - 1 of 1\nFull-Text Articles in Education “So, That’S Sort Of Wonderful”: The Ideology Of Commitment And The Labor Of Contingency, Sarah V. Seeley The Journal of the Assembly for Expanded Perspectives on Learning\nThis article explores the emotional outcomes related to language commodification within an organizational context: the first-year writing program at Binghamton University, which is a public research university in upstate New York. In this setting, the meanings of effective writing instruction are discursively constructed in terms of a multi-faceted commitment to ‘the process.’ This entails an ideological commitment to both recursive process writing and the process of collaboratively evaluating the product that derives from it. I first offer an overview of the Binghamton context, including the details of collaborative portfolio assessment. I then analyze a specific sociolinguistic strategy: pep talking. I ...", "pred_label": "__label__POS", "pred_score_pos": 0.9701032042503357}
{"content": "AFRICA: Despite improved harvests in parts, the food supply situation in eastern Africa remains precarious, with about 18 million people still in need of food assistance. The number of refugees and internally displaced people due to civil strife continues to increase, particularly in Central and Western Africa. The situation of Sierra Leone and refugees in Guinea gives cause for serious concern. Localized food shortages have emerged in Chad, Burkina Faso and Niger, while a prolonged dry spell and floods in several locations in southern Africa could adversely affect the current season's food production.", "pred_label": "__label__POS", "pred_score_pos": 0.9423841238021851}
{"content": "Water-quality sensors are exposed to changing environments and extreme weather conditions and thus are prone to errors, including failure. These technical errors make data unreliable and untrustworthy and affect performance of any subsequent data analysis. ACEMS researchers, led by Priyanga Dilini Talagala, have proposed a feature based procedure, named oddwater, for detecting technical outliers in water-quality data derived from in situ sensors.", "pred_label": "__label__POS", "pred_score_pos": 0.7757207155227661}
{"content": "Understanding the decline of regional party power in the 2019 national election and beyond\nIn this piece, we argue that the electoral performance of the BJP, and the popularity of Narendra Modi, has significantly altered the dynamic of regional party politics in India. The BJP’s undiluted power at the Centre has created the political context for greater centralization of power. This in turn has generated greater distinctions between regional and national politics. The popularity of Prime Minister Modi combined with his party’s ideological project generates a deeply centralized national politics that can be easily distinguished from regional politics for the voter. This increasingly distinct form of national politics weakens the role of regional parties in national politics, both in electoral terms and in bargaining power, as regional parties rarely have well-defined, credible national policy platforms in India. However, it does, for the moment, appear to strengthen the electoral position of regional parties at the state level.", "pred_label": "__label__POS", "pred_score_pos": 0.7987583875656128}
{"content": "I provide engaging and interactive workshops including:\n1.\nTrauma-informed schools\nThis training focuses on engaging educators in discussions and reflections about social emotional learning and challenges and best practice within schools. It includes the following:\nDefining trauma Affects of trauma on the brain, behaviours, and emotional regulation What trauma-informed classrooms look like Trauma-informed de-escalation strategies\n2.\nTeacher self-care\nThis workshop looks at the importance of teacher self-care and emotional awareness in order to avoid burnout. This course includes:\nSigns of burnout What self-care can look like within the context of schools and classrooms How teacher self-care can be incorporated into daily practices How positive teacher mental health affects the classroom environment Self-reflective teaching practices to avoid burnout\n3.\nPlaytime: putting play in the school day\nThis highly interactive workshop explores the importance of play in child development and for promotion of positive mental health. This workshop includes:\nThe ‘function’ of play Play in childhood development Play in empathy development and emotional regulation Further incorporating play into the school day\n4.\nEmotionally literate classrooms\nThis workshop focuses on creative and engaging ways to assist students in understanding their experiences and emotions. This workshop includes:\nUnderstanding the physical nature of emotional regulation Including emotional literacy and understanding in daily classroom interactions Creative interventions which can be used in classrooms to promote emotional literacy and discussions\n5.\nTailor-made workshops:\nI have experience crafting unique programs for institutions with vastly different needs. To explore how I can help your business or team, click the button!", "pred_label": "__label__POS", "pred_score_pos": 0.9729729294776917}
{"content": "Last week, the Government announced that the range of businesses eligible for the Coronavirus Business Interruption Loan Scheme had been extended.\nUnder the new eligibility, agencies classed as undertakings in difficulty, with fewer than 50 employees and turnover of less than £9m, can now apply for a loan under the CBILS.\nDavid Clasen, Finance Director, IPA added: \"The IPA continues to prompt the Government, pointing to potential initiatives which would allow more agencies to support its growth agenda. This enhancement could be a life-saver for smaller agencies with high levels of debt and accumulated losses.\"", "pred_label": "__label__POS", "pred_score_pos": 0.5756281614303589}
{"content": "Real Estate Law in Oklahoma\nChoctaw's real estate industry is controlled by a huge body of laws. This is because almost any real estate transaction invokes laws regarding civil rights, consumer protection, land use, and contracts.\nThe wide volume of laws regulating real estate in Choctaw might seem overwhelming to the uninitiated. Indeed, they can get very complicated, especially when issues about title defects or construction disputes are involved.\nTherefore, it's a good idea to learn some of the basics of Choctaw's real estate laws.\nHaving at least some knowledge of real estate law will be to your advantage in practically any real estate transaction. Knowing the law can give you a bargaining advantage and prevent you from being saddled with obligations that you don't have to assume.\nCommon Real Estate Law Issues in Choctaw\nFinancing: Most persons, families, and small businesses in Choctaw cannot afford to buy a large piece of real estate with the money they have on hand. However, they typically can afford to pay for it over a long period of time, in installments, with interest. Thus, most real estate is purchased using a mortgage - a loan for a specific purchase, using the item purchased as collateral.\nZoning: Zoning regulations govern what types of structures are allowed on various parcels, based on their location in a municipality. For example, some areas in a city might be zoned only for residential use. Another area might authorize industrial use. These rules are meant to keep property values up, and promote harmony among neighbors by preventing conflicts.\nDuty to Disclose: If you're buying a house in Choctaw, you have particular legal protections. The seller has a duty to tell the buyer about any defects that the property has. All defects which the seller knows about, and which the buyer can't be expected to discover through an ordinary inspection, must be disclosed. If the seller fails to disclose a defect, and the buyer later discovers it, the seller can be sued for any diminution in the property's value caused by the defect, the cost of repairing it, and any injuries the buyers suffers as a result.\nImplied Warranties: In Choctaw, every residential lease agreement, whether it's clearly stated or not, has an \"implied warranty of habitability.\" This is a legally-imposed promise by the landlord that the rented dwelling (whether it's a house or apartment) is fit for habitation by humans. While there are many requirements for a place to be considered habitable, some of the most crucial ones are electricity, running water, heating, and protection from the elements.\nCan a Choctaw Real Estate Lawyer Help?\nThese issues, along with many others, can sometimes be fairly difficult. Therefore, you should never hesitate to consult with a Choctaw real estate attorney if you have any questions.", "pred_label": "__label__POS", "pred_score_pos": 0.6514756679534912}
{"content": "In an effort to help reduce stress and building resilience for essential healthcare workers during the COVID-19 pandemic, Service Employees International Union-United Healthcare Workers West (SEIU-UHW) partnered with Lumos Transforms to make The Resilience Toolkit available to the union’s 97,000 members and leaders.\nHealthcare workers are facing unprecedented levels of stress as they navigate the COVID-19 pandemic in the workplace and in their personal lives. The Resilience Toolkit utilizes promising stress reduction practices that reconnect people to a sense of relaxation and hope, even during difficult circumstances. By giving SEIU-UHW members self-care practices that are truly effective, within an accessible and sustainable framework, The Resilience Toolkit aims to help them grow resilience over time.\nThe partnership between Lumos and SEIU-West included a series of live kick off events for members, conducted on Facebook. Members then opted in to The Resilience Toolkit training – a self-paced, six module video series facilitated by Nkem Ndefo, creator of The Resilience Toolkit and founder of Lumos Transforms. To further support workers on their journey, participants can attend 25-minute live video sessions, where they can ask questions, receive guidance, and connect with others who are using The Toolkit to help them through this difficult time.\nIn the Coronavirus era, frontline healthcare workers are expected to operate at increased capacity, under a sustained level of high stress. Now more than ever, it’s important for these workers to have accessible frameworks that not only get them through the work day, but help them rest and recover when they return home.", "pred_label": "__label__POS", "pred_score_pos": 0.92628014087677}
{"content": "A Spatial Hedonic Analysis of the Effects of Wind Energy Facilities on Surrounding Property Values in the United States You are here\nThis report summarizes a new analysis, building on previously published research, about wind energy’s effects on residential property values. This study helps fill research gaps by collecting and analyzing data from 27 counties across nine U.S. states, related to 67 different wind facilities, and constructs a pooled model that investigates average effects near the turbines across the sample while controlling for local variables, such as sale prices of nearby homes.", "pred_label": "__label__POS", "pred_score_pos": 0.890617311000824}
{"content": "Primary care is often the weakest link in many health systems. It is also the most important. This article describes a framework for the design of primary care systems that are responsive to local needs. It serves as a guide to understand and navigate the complex issues of primary care delivery.", "pred_label": "__label__POS", "pred_score_pos": 0.9993295669555664}
{"content": "NEUROLOGICAL, ORTHOPEDIC &\nPAIN MANAGEMENT\nTemporomandibular joint pain\nTemporomandibular Joint Pain is a widespread condition that affects roughly 12% of US population, yet there is little help offered by Western conventional medicine. Dentists dislike treating TMJ as they are unable to deliver consistent results. This is not a surprise as TMJ is not a dental problem, it is more often caused by muscle inhibition in a cervical spine and shoulder girdle muscle groups. Research supports the relationship between the two. At Mulberry Leaf we go through a detailed assessment to find the muscle imbalance and pinpoint the root of the problem. We successfully treat TMJ by restoring motor inhibition and joint function, addressing muscle tension, reducing inflammation and pain. We utilize intraoral massage, acupuncture and a functional motor point therapy to ensure long-lasting results.", "pred_label": "__label__POS", "pred_score_pos": 0.7358681559562683}
{"content": "Intrusive memories to traumatic footage: the neural basis of their encoding and involuntary recall Clark IA., Holmes EA., Woolrich MW., Mackay CE.\n<jats:sec id=\"S0033291715002007_sec_a1\"><jats:title>Background</jats:title><jats:p>A hallmark symptom after psychological trauma is the presence of intrusive memories. It is unclear why only some moments of trauma become intrusive, and how these memories involuntarily return to mind. Understanding the neural mechanisms involved in the encoding and involuntary recall of intrusive memories may elucidate these questions.</jats:p></jats:sec><jats:sec id=\"S0033291715002007_sec_a2\" sec-type=\"methods\"><jats:title>Method</jats:title><jats:p>Participants (<jats:italic>n</jats:italic> = 35) underwent functional magnetic resonance imaging (fMRI) while being exposed to traumatic film footage. After film viewing, participants indicated within the scanner, while undergoing fMRI, if they experienced an intrusive memory of the film. Further intrusive memories in daily life were recorded for 7 days. After 7 days, participants completed a recognition memory test. Intrusive memory encoding was captured by comparing activity at the time of viewing ‘Intrusive scenes’ (scenes recalled involuntarily), ‘Control scenes’ (scenes never recalled involuntarily) and ‘Potential scenes’ (scenes recalled involuntarily by others but not that individual). Signal change associated with intrusive memory involuntary recall was modelled using finite impulse response basis functions.</jats:p></jats:sec><jats:sec id=\"S0033291715002007_sec_a3\" sec-type=\"results\"><jats:title>Results</jats:title><jats:p>We found a widespread pattern of increased activation for Intrusive <jats:italic>v</jats:italic>. both Potential and Control scenes at encoding. The left inferior frontal gyrus and middle temporal gyrus showed increased activity in Intrusive scenes compared with Potential scenes, but not in Intrusive scenes compared with Control scenes. This pattern of activation persisted when taking recognition memory performance into account. Intrusive memory involuntary recall was characterized by activity in frontal regions, notably the left inferior frontal gyrus.</jats:p></jats:sec><jats:sec id=\"S0033291715002007_sec_a4\" sec-type=\"conclusion\"><jats:title>Conclusions</jats:title><jats:p>The left inferior frontal gyrus may be implicated in both the encoding and involuntary recall of intrusive memories.</jats:p></jats:sec>", "pred_label": "__label__POS", "pred_score_pos": 0.8013904690742493}
{"content": "This bill clearly violates the first amendment, people should be able to share ideas, and communicate with others without having to register with the government.\nSimply put: Even if you never talk to an elected official but spend as little as $500 merely to communicate with your neighbors and friends about state policies, you must register with, and provide information to, the government, which then proceeds to disseminate the information on the Internet. Failure to register can lead to an investigation, significant penalties (including treble damages, the costs of the investigation and the government’s attorney’s fees), and a revocation of the ability to engage in any political activity that might qualify as “grassroots lobbying.”", "pred_label": "__label__POS", "pred_score_pos": 0.8511594533920288}
{"content": "Free -day delivery on orders over $49*\nHike, trek, drive, paddle or ride, any adventure requires a good map, it ensures you reach your destination and take in all the side trips along the way, and are particularly useful in an emergency. Different adventures require different types of maps, you may need a combination of these to make sure you safely navigate your way through the activities you have planned.\nThese are the most detailed maps an usually show smaller parcels on land with contour lines and features that are particularly relevant to non-vehicle based activities such as hiking, bicycle touring and kayak adventures. If you like to explore every crevice, escarpment, valley or point of interest on a map that doesn't have a defined path leading to it, then you need a topographic map along with a reliable compass and some map reading skills.\nThese are often topographic like maps that are produced to cater for hikers and trekkers sticking to a defined walking trail such as the Larapinta or Heysen Trails or the Bibblemum Track. The benefit of these over a topographic map is that they will have track/trail-specific information such as shelters & campsites, rainwater tank locations, food drop points & vehicle access tracks as well as some information on surrounding areas. If your adventure involves sticking to a defined track or trail, then a map guide if what you need.\nThe faster pace of a vehicle means you don't need all the topographic detail of a hiking map. 4wd touring maps feature significant routes, points of interest along the way and important information such as fuel locations, mechanical repair points and often local contact details for roadhouses and station owners. A 4wd touring map will feature both sealed and unsealed roads but their focus is to help you get off the sealed road. They will also often mark the locations of significant campsites and historical stops along the way.\nNot everyone has a vehicle that can handle the rigours outback travel, and a lot of people just like the idea of a good old-fashioned road trip that follows sealed roads from town to town across the country. These maps are a great guide to help you find the road less travelled between major points of interest. They will help you plan fuel stops, accommodation such as campsites, caravan parks, national parks as well as stops at tourist attractions.\nExciting news, your order has left our warehouse! If you'd like to keep an eye on it's journey, click the button below.\nOh and don't forget to\ncopy your tracking number. Carrier:\nTracking number:\nIf you find one of our products cheaper with any other Australian retailer, we’ll match it.\nJust make a note of the price and where you have found it, and then give us a call on the following number:", "pred_label": "__label__POS", "pred_score_pos": 0.5740197896957397}
{"content": "Contentious contract negotiations, like those involving the School District and the teachers’ union, are usually at heart a battle of narratives – between management, which is often in financial crisis, and labor, whose narrative is about protecting beleaguered workers from being exploited. They are rarely a celebration of hard data and facts about hiring, compensation and policies.\nThat’s presumably why Jerry Jordan, head of the Philadelphia Federation of Teachers, has questioned the timing and the funding behind a new report investigating policies covering teacher tenure, performance and pay at the School District.", "pred_label": "__label__POS", "pred_score_pos": 0.8804600834846497}
{"content": "By Oluwamurewa Fashoro\nArchitecture is both the process and the product of planning, designing, and constructing buildings or other structures. Job is constantly evolving.\nArchitects are not artists – they have to address building technology and programming. There are constantly evolving materials and construction methods out there and we are required as a profession to address the demands of the public at large (building performance, energy consumption, incorporating recycled materials, etc.).\nThey can positively impact peoples lives.\nIt is rewarding to develop a personal relationship with your client, particularly when you know that the process will yield a more fruitful end product.\nTo Become a Brilliant Problem Solver.\nArchitecture school teaches you to take a pile of data and information and interpret it to inform how to design a building or solve a problem.", "pred_label": "__label__POS", "pred_score_pos": 0.5190805792808533}
{"content": "Abstract\nBACKGROUND: Hypertension (high blood pressure) is a common long-term health condition. Patient involvement in treating and monitoring hypertension is essential. Control of hypertension improves population cardiovascular outcomes. However, for an individual, potential benefits and harms of treatment are finely balanced. Shared decision making has the potential to align decisions with the preferences and values of patients.\nOBJECTIVE: Determine the effectiveness of interventions to support shared decision making in hypertension.\nSEARCH STRATEGY: Searches in MEDLINE, EMBASE, CINAHL, Web of Science and PsycINFO up to 30 September 2017.\nELIGIBILITY CRITERIA: Controlled studies evaluating the effects of shared decision-making interventions for adults with hypertension compared with any comparator in any setting and reporting any outcome measures.\nRESULTS: Six studies (five randomized controlled trials) in European primary care were included. Main intervention components were as follows: training for health-care professionals, decision aids, patient coaching and a patient leaflet. Four studies, none at low risk of bias, reported a measure of shared decision making; the intervention increased shared decision making in one study. Four studies reported blood pressure between 6 months and 3 years after the intervention; there was no difference in blood pressure between intervention and control groups in any study. Lack of comparability between studies prevented meta-analysis.\nCONCLUSIONS: Despite widespread calls for shared decision making to be embedded in health care, there is little evidence to inform shared decision making for hypertension, one of the most common conditions managed in primary care.", "pred_label": "__label__POS", "pred_score_pos": 0.8433137536048889}
{"content": "Abstract\nPrior research has shown that an established organic farm can be as profitable as a conventional farm under certain circumstances. However, organic farming systems often require a transition period before they are fully established after a changeover from conventional farming. Yields may decrease and recover only slowly during this transition period and less profitable crop rotations may be required to establish an organic system. Previous studies have ignored the income trend during the transition phase, and comparisons of organic and conventional farms have been faulted for lack of similarity in management and other resources. The study reported here used a multiyear simulation model to investigate the trend in income of a 117-hectare crop-livestock farm in Pennsylvania (called the Kutztown farm) during this transition process. A baseline model of the Kutztown farm under conventional management (CONB) was found to earn an income (returns over cash operating cost) of $61,900. The transitional models developed were an upper-yield case assuming no yield decline during the transition (TRANS) and a lower-yield case assuming severe yield decline in the first year after the change-over from conventional management and a subsequent linear recovery of yields over a three-year period (TRANS-L). Income was found to be severely depressed by a yield decline during the transitional phase. The first year of TRANS-L resulted in a 43% reduction in income. The scenario without a yield decline (TRANS) resulted in a 13% lower income compared to the baseline (CONB) model. Both transitional models led to an established organic situation with stable organic yields and an income of $57,400 or 7% less than under conventional management. It was found to be more profitable to sell the crops and purchase manure than to feed the crops to beef in a fattening enterprise. At small herd sizes (100 head) the reduction in income caused by the feeding operation was moderate ($1,300), but with a larger operation (213 head) the income sacrifice increased tenfold.", "pred_label": "__label__POS", "pred_score_pos": 0.7766961455345154}
{"content": "Disagreements and disputes in the business world occur every day. In many cases they concern the terms of a contract and the Uniform Commercial Code. ForensisGroup can connect you with business disputes expert witnesses who have decades of legal experience as practicing attorneys.\nThese professionals devote their practices to financial and business transactions, such as civil and bankruptcy matters, lender liability lawsuits, and litigation over the legal and business aspects of secured and unsecured lending for all types of credit facilities. Other attorneys specialize in disputes involving real property, including foreclosures, easements, native land rights, mineral rights, construction loans, mechanics’ liens, landlord-tenant issues, mortgages, trust deeds, restrictive covenants, water rights, priorities and recording, encroachments, boundaries, and fiduciary responsibilities. Some have expertise in corporate, securities, and business law issues. This includes complex civil litigation, public and private securities offerings, corporate governance, standard of care issues, contract preparation, malpractice, executive employment agreements and compensation, stock options, and other equity based compensation arrangements.\nOur business disputes expert witnesses also have experience with insurance disputes in general liability, title insurance, bad faith, reservation of rights, policy interpretation, and subrogation. They have served as expert witnesses in cases involving franchisee/franchisor agreements, business partnerships, breach of fiduciary duty, malfeasance, self-dealing, and corporate governance with corporate officer responsibilities and duties.\nAt ForensisGroup, we carefully evaluate each one of our professionals to ensure exceptional ability, achievement, and experience to ensure a quality experience for our clients. Contact ForensisGroup at 1-800-5422 or submit an expert request form to find top expert witnesses for your case.", "pred_label": "__label__POS", "pred_score_pos": 0.5151249766349792}
{"content": "1. Am I covered in case I contract Covid-19 while I’m travelling abroad? Expenses linked to Covid-19 (e.g.: specialised medical treatments or repatriation) are notcovered. What is covered is the immediate life-saving medicalcare in the first hours on admission, if required, and the Covid-19 test. 2. Does my insurance remain valid in case of medical emergency? Yes, your coverage remains valid, subject to the conditions and limits of your policy. Please also note that: In case of diving emergency, the coverage is valid provided there are no restrictions placed on diving activities in the area where you intend to dive. In case of non-diving emergencies abroad, expenses associated to Covid-19 are excluded. 3. Do I get any compensation if my trip ends up being disrupted by Covid-19? Unlike standard travel insurances, DAN Europe plans exclusively focus on medical emergencies. As a result, the consequences of travel disruptions caused by Covid-19 are not covered. For instance, if your flight were to be cancelled, your expenses would not be taken on by the insurers as this does not constitute a medical emergency. See also: Is a standard travel insurance included other than the diving insurance? 4. My country advises against travelling to my destination because of the Covid-19 pandemic. Am I still covered if I make the decision to travel anyway? Yes, your insurance cover remains valid even if you decide to travel against the advice of your government. However, please note that DAN may be unable to assist you as effectively as it would under normal circumstances, due to the serious logistical issues the pandemic may cause in any given area. For instance, arranging a repatriation may be unfeasible due to border closures; likewise, medical facilities might be overwhelmed or unavailable altogether. In light of this, please follow carefully the indications of the government of your country of residence as well as those of local authorities. See also: COVID-19 and DAN Europe Membership, Assistance & Insurance", "pred_label": "__label__POS", "pred_score_pos": 0.5955978631973267}
{"content": "An interaction between a star-disc system and another star will perturb the disc, possibly resulting in a significant modification of the disc structure and its properties. It is still unclear if such an encounter can trigger fragmentation of the disc to form brown dwarfs or gas giant planets. This paper details high-resolution smoothed particle hydrodynamics (SPH) simulations investigating the influence of stellar encounters on disc dynamics. Star-star encounters (where the primary has a self-gravitating, marginally stable protostellar disc, and the secondary has no disc) were simulated with various orbital parameters to investigate the resulting disc structure and dynamics. This work is the first of its kind to incorporate realistic radiative transfer techniques to realistically model the resulting thermodynamics. The results suggest that the effect of stellar encounters is to prohibit fragmentation -compressive and shock heating stabilizes the disc, and the radiative cooling is insufficient to trigger gravitational instability. The encounter strips the outer regions of the disc (either through tidal tails or by capture of matter to form a disc around the secondary),which triggers a readjustment of the primary disc to a steeper surface density profile (and a flatter Toomre Q profile). The disc around the secondary plays a role in the potential capture of the secondary to forma binary. However, this applies only to orbits that are parabolic -hyperbolic encounters do not form a secondary disc, and are not captured.\nID: 1231315", "pred_label": "__label__POS", "pred_score_pos": 0.9284605979919434}
{"content": "Nelson, E. A., Keller, G. L., Mitchell, T. W. et al. 2010. A jugular bleeding technique in rabbits. Lab Animal 39(1), 17-22.\nWhen studying pharmacokinetics in rabbits, researchers must often take multiple blood samples from conscious rabbits. Researchers usually collect these samples via the auricular vein, typically through a port or an indwelling catheter. The authors have developed an easy and efficient alternative method for obtaining multiple blood samples from conscious rabbits via the external jugular vein. This jugular bleeding technique serves as a refinement to blood sampling methods that require rabbits to undergo surgery (e.g., to insert a port) because it requires no alleviation of pain. During a 2-year period, the authors have taken multiple blood samples from more than 400 rabbits and have seen no adverse events attributed to this procedure.", "pred_label": "__label__POS", "pred_score_pos": 0.9984660148620605}
{"content": "Do your surroundings overwhelm and hamper your life? Are you aware of how they impact your experience of working, playing, and living?\nIn this episode, Matthew outlines how to be conscious of the places and spaces within which we live our lives and how not to allow them to dictate to us. You can choose and shape everything about your life, including your character, your body, your relationships, your work, your style, and–of course–your environments.\nGet on the same page with your friends, teammates, co-workers–and most importantly–your dearest ones to more fully achieve your goals and have fewer frustrating fights.\nIn this episode, Matthew discusses and illustrates why constant communication is paramount in “merging your values” with those whose lives are tied to your own, particularly your loved ones. He highlights the reasons why partnerships flounder and fail, and offers the constructive means by which successful associations (including couples) create a “culture” or “identity” towards joyful progress.\nBecause health is such a crucial value and because I think and act a lot on it, I intend to share occasional posts of what might be useful leads in regard to exercise, lifestyle, and nutrition, mostly in the way of results of various practices I’ve tried and by discussing how I think of them. But I think this can only be useful if I and any readers are mindful of how to take them.", "pred_label": "__label__POS", "pred_score_pos": 0.9768409729003906}
{"content": "Cannabis became legal in Saskatchewan and nationwide in Canada on October 17, 2018. Adults 19 years or older are now legally allowed to purchase, possess, consume and cultivate cannabis in the province.\nTo ensure that their respective province’s legal cannabis industry operates with the health and safety of its residents in mind, government officials passed Saskatchewan’s Cannabis Framework. The legislation defines what is legal from both a consumer and retail standpoint and aims to ensure public safety and a successful cannabis industry.", "pred_label": "__label__POS", "pred_score_pos": 0.999977171421051}
{"content": "The UK Government has published the UK Electrical Equipment (Safety) Regulations 2016 and the UK Electromagnetic Compatibility Regulations 2016. These transpose the most recent Low Voltage Directive (LVD) and Electromagnetic Compatibility (EMC) Directive which should have been brought into national law in April.\nFor the LVD, the European Commission has published a guidance document and listed the Harmonised Standards which can be used to demonstrate compliance, but with three omissions compared with the previous listing. As previously reported, the UK and German Governments had objected under the previous LVD that the standards for refrigeration, small ovens, and blenders were insufficient to prove that the products were safe. There has been some suggestion that the Commission’s refusal to re-list these standards was not in accordance with the proper process, as the safety requirements have not actually changed. However, the fact remains that until these standards are listed, manufacturers have no presumption of conformity, to demonstrate that their products meet the requirements of the legislation.", "pred_label": "__label__POS", "pred_score_pos": 0.975909948348999}
{"content": "If you are like many adults who take pride in their car, truck, or SUV, you probably make vehicle maintenance a top priority. Checking the oil and other fluid levels, ensuring that your tires are aired up and the tread is not too worn, and taking your vehicle in for regular tune-ups may be a standard part of your routine. However, when defective design or manufacture of an auto part is to blame for a malfunctioning vehicle, there may be nothing the driver could have done to prevent it. If you or a loved one were injured in an accident, and you believe that defective tires were to blame, you may have a valid product liability case.\nHistory of Faulty Car and Truck Tires\nMany people still remember when the Firestone Tire and Rubber Company was forced to conduct one of the largest recalls in U.S. history. Defective tires installed on Ford pickup trucks and SUVs were associated with accidents causing over 800 injuries and 270 deaths. Firestone eventually recalled a staggering 6.5 million tires, and the Ford Motor Company recalled and replaced approximately 13 million of the defective tires. Ford faced over $600 million in lawsuits as a result.\nUnfortunately, tire recalls are not limited to just these companies. Just recently, Alliance Tire Americas issued a tire recall after it was discovered that the tread might separate from the casing during use. Flaws in the design and manufacture of tires can cause the tires to malfunction and put the lives of drivers, passengers, and pedestrians at risk....", "pred_label": "__label__POS", "pred_score_pos": 0.5967657566070557}
{"content": "LEARN MORE ABOUT THE COLLECTIVE IMPACT APPROACH\nCollective Impact is a framework to tackle deeply entrenched and complex social problems. It is an innovative and structured approach to making collaboration work across government, business, philanthropy, non-profit organisations and citizens to achieve significant and lasting social change. The Collective Impact approach is premised on the belief that no single policy, government department, organisation or program can tackle or solve the increasingly complex social problems we face as a society. The approach calls for multiple organisations or entities from different sectors to abandon their own agenda in favour of a common agenda, shared measurement and alignment of effort. Unlike collaboration or partnership, Collective Impact initiatives have centralised infrastructure – known as a backbone organisation – with dedicated staff whose role is to help participating organisations shift from acting alone to acting together.", "pred_label": "__label__POS", "pred_score_pos": 0.8581562042236328}
{"content": "On July 14, 2016, the Internal Revenue Service (the “IRS”) and the U.S. Treasury Department (“Treasury”) issued proposed regulations that are designed to limit taxpayers’ ability to engage in tax-free distributions under Section 355 (a “Section 355 Distribution”) in situations where either the distributing corporation (“Distributing”) or the controlled corporation (“Controlled”), or both, holds a disproportionally large amount of non-business assets (such as cash or a minority position in another corporation) in comparison to its business assets.", "pred_label": "__label__POS", "pred_score_pos": 0.9662112593650818}
{"content": "As the amount of global data increases exponentially, so do the challenges related to the process of legal holds.\nIDC predicts that worldwide electronic data will reach 175 zettabytes by 2025, with an average person creating and participating in up to 5,000 digital interactions a day.1 What does that amount of data look like? One publication explains it like this: “A single zettabyte will fill 1,000 datacenters or about 20% of Manhattan.”2\nThat’s a lot of data – especially for corporations with hundreds or thousands of employees and locations worldwide.\nNow consider this amount of data in the context of a legal hold. When you combine the sheer amount of data with the fact that it exists on multiple systems, mobile devices, cloud-based solutions and in shared and private drives, it vastly complicates the process.\nYet, many companies still rely on email to manage legal holds.\nPreserving Data\nIt’s now more important than ever to preserve electronically stored information (ESI) correctly – especially when undergoing litigation.\nThe Federal Rules of Civil Procedure 37(e)3 states that:\nIf electronically stored information that should have been preserved in the anticipation or conduct of litigation is lost because a party failed to take reasonable steps to preserve it, and it cannot be restored or replaced through additional discovery, the court: (1) upon finding prejudice to another party from loss of the information, may order measures no greater than necessary to cure the prejudice; or (2) only upon finding that the party acted with the intent to deprive another party of the information’s use in the litigation may: (A) presume that the lost information was unfavorable to the party; (B) instruct the jury that it may or must presume the information was unfavorable to the party; or (C) dismiss the action or enter a default judgment.\nIf ESI isn’t preserved in accordance to discovery, judges can impose monetary penalties or even rule against the party that lost the information.\nThe Importance of a Legal Holds Solution\nIdeal legal holds solutions work on multiple levels. They enable corporate legal departments to notify custodians of their duty to preserve information in a timely manner while collecting and storing custodian acknowledgements, questions, preserve notices and data in a secure location. It also offers real-time tracking so team members know the status of collection requests, when actions were issued, which tasks are in progress and which legal actions require immediate attention. The tool should also create comprehensive dashboard views, allowing those involved to see when a custodian leaves an organization. From there, they can enable email archiving or suspend the destruction of data.\nAutomation plays a vital role in a legal holds solution. It relieves the burden of manual work with automated workflows that can be configured to match a company’s legal hold process. It also provides automatic notifications and reminders to support compliance.\nLegal Holds Solution Benefits\nAside from these features, how does a legal hold solution benefit a corporate legal department?\nFirst, they ensure compliance. Real-time dashboards, reports and audit trails ensure relevant data is collected and preserved – demonstrating that the proper care has happened to preserve and collect digital evidence. Processes supported by legal holds technology also demonstrate an appropriate level of diligence as automation reduces the chances for human error.\nNext, when based on a low- or no-code platform, a legal hold solution enables a quick setup and deployment with little to no IT involvement, increasing time to value.\nThey also enhance overall visibility into the legal hold process, which is imperative for companies undergoing numerous cases. By being available on multiple browsers or devices, it allows easy access to information.\nFinally, a legal holds solution can also reduce costs by tracking budgets and spend by matter, matter type or law firm.\nConclusion\nWhether it is for one case or many, technology can reduce the complications of legal holds in today’s data-heavy business environment while minimizing risk. If you’d like to learn more about a legal holds solution, visit here.", "pred_label": "__label__POS", "pred_score_pos": 0.5239601135253906}
{"content": "The Study of animal communication has a long and colorful history. In the 1950s Dutch biologist Niko Tinbergen collected stickleback fish and carefully observed how they interacted. He noticed that the abdomen of male fish would flush bright red during breeding season, as the fish built nests and established their territories. This color served as a warning signal to rivals—so much so that Tinbergen found that territorial males would lunge at any object with a similar hue, including wood blocks he held outside their tank and even a mail van passing by the laboratory window.", "pred_label": "__label__POS", "pred_score_pos": 0.7872476577758789}
{"content": "These procedures are recommended less frequently for cervical dystonia in light of the availability of less aggressive, but effective, therapies such as botulinum toxin injections and deep brain stimulation.\nThis content originally appeared on the Dystonia Medical Research Foundation website at www.dystonia-foundation.org.\nContinue Learning about Dystonia\nImportant: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.", "pred_label": "__label__POS", "pred_score_pos": 0.9977107644081116}
{"content": "Each day,\nYWCA Mohawk Valley provides a lifeline for individuals and families fleeing domestic and sexual violence. But this year, the demand for our emergency services reached unprecedented levels.\nQuarantine and isolation kept those living with violence and abuse trapped at home. Our 24-hour emergency shelters were at capacity, hundreds reached out desperately to our free and confidential crisis hotlines, and even more sought advocacy and support.\nWe have been busier than we could have ever imagined, but because of you, we are not alone. Because of you, we have been able to continue working and saving lives through a global pandemic. You are why we are able to fulfill our tireless mission to eliminate racism, empower women, and promote peace, justice, freedom, and dignity for all.\nAs we continue to navigate through uncertain times, YWCA Mohawk Valley needs\nyou. You\nare delivering financial independence to mothers who have experienced abuse and are fleeing to safety with their children.\nYou\nare educating our youth who are vulnerable to violence, teaching them to recognize and prevent abuse in any form.\nYou\nare giving children in the Mohawk Valley a safer home and a chance to achieve their dreams.\nYour support is how we make a difference and save lives.", "pred_label": "__label__POS", "pred_score_pos": 0.7058488130569458}
{"content": "A coalition of sustainability leaders including the Australian Sustainable Building Council's (ASBEC) Sustainable Housing Task Group, the NSW Office of Environment and Heritage (OEH), CSIRO and the Green Building Council of Australia (GBCA) are developing the Sustainable Housing Industry Roadmap based on the work of the NSW Collaborative Sustainable Housing Initiative (CSHI) and the research of the CRC for Low Carbon Living (CRCLCL) (RP3009, RP3016, RP3021, RP3028).\nThis project supplements the previous work by answering additional research questions around the\nvalue proposition of Sustainable Housing for the Construction Industry.\nBy demonstrating the economic value proposition for delivering sustainable housing that exceeds the minimum standards, the Roadmap aims to engage the construction industry in a new dialogue around\nmarket based solutions.\nThis contrasts with (but complements) other CRC research (SP0009, SP0016) which focuses on regulatory solutions.", "pred_label": "__label__POS", "pred_score_pos": 0.9658098220825195}
{"content": "When I was a kid, my dad would let me sit on the riding lawn mower with him as he cut the grass. By the time I got to middle school, I was too big to ride with him, but I’d done it for years. At the mature age of twelve, he finally let me drive it myself. I felt a big sense of responsibility. I was intimidated by the machine, but I thought I could probably handle it. Well, I wasn’t sure I could handle it, but I thought I should definitely try. That’s the story of my life.\nI made a couple loops around the yard successfully but then things took a turn for the worst. We had a fence around our yard and a smaller portion of fence that separated an area for my dog to use while we were away from home.\nAfter my initial triumph, I somehow veered off path. I was heading straight for a portion of the fence that met the exterior of our house. In my panic, I couldn’t figure out how to steer or slow down. I had no control over my body or the mower. All I could do was stare into the impending doom and prepare myself for inevitable disaster. My dad saw it going down and, with only minor panic, ran over. He got to me before I took the fence down or smashed into the brick wall, but not before I crushed a few posts.\nHe said, “Well, that’s enough of that.” I was not allowed to drive the mower again. I’d like to think I learned a lesson that day, but I don’t know what it was. I still “fake it til I make it” with most of my just-out-of-reach goals and I stand by that mantra. Maybe it was that my dad has my back. Or maybe it was that I’m just not meant for hard labor, which is a lesson I’ll carry with me forever.", "pred_label": "__label__POS", "pred_score_pos": 0.7185544967651367}
{"content": "As demand for bandwidth increases in systems-on-a-chip and chip multiprocessors, networks are fast replacing buses and dedicated wires as the pervasive interconnect fabric for on-chip communication. The tight delay requirements faced by on-chip networks have resulted in prior microarchitectures being largely performance-driven. While performance is a critical metric, on-chip networks are also extremely power-constrained. In this paper, we investigate on-chip network microarchitectures from a power-driven perspective. We first analyze the power dissipation of existing network microarchitectures, highlighting insights that prompt us to devise several power-efficient network microarchitectures: segmented crossbar, cut-through crossbar and write-through buffer. We also study and uncover the power saving potential of existing network architecture: express cube. These techniques are evaluated with synthetic as well as real chip multiprocessor traces, showing a reduction in network power of up to 44.9%, along with no degradation in network performance, and even improved latency-throughput in some cases.", "pred_label": "__label__POS", "pred_score_pos": 0.980478823184967}
{"content": "Drug overdoses are now the leading cause of accidental death in the United States, with an estimated 60,000 deaths in 2016. Nationally, EMS overdose responses with naloxone administration have nearly doubled from 2012 to 2016 from 573.6 to 1004.4 per 100,000 EMS events. Resuscitation using the opioid antagonist, naloxone is recommended in cases of suspected opioid ODs, and has been increasingly used by EMS agencies, law enforcement, healthcare providers, and Good Samaritans.", "pred_label": "__label__POS", "pred_score_pos": 0.9541250467300415}
{"content": "Medicare is one of the largest social programs in the world. Did organized industry favor Medicare's passage in 1965? If it did, this would represent powerful evidence in favor of the theory that social programs typically require cross-class alliances to pass, such as alliances between business and labor. However, in a previous article in this journal, I argued that answering questions about political actors’ preferences—such as whether organized industry favored Medicare's passage—can be surprisingly difficult due to the “problem of preferences”; that is, political actors might misrepresent their true policy preferences for many reasons. For example, when their ideal proposals are not politically feasible, political actors may wish to bolster support for a more politically viable alternative to a disliked proposal—even if they do not truly support this alternative to the status quo. To better understand political actors’ true policy preferences, I argued, scholars should trace how those actors’ expressed preferences change as a function of their strategic context—just as scholars seeking to understand the impact of any other variable trace the effects of changes in it.\n* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.\nUsage data cannot currently be displayed.", "pred_label": "__label__POS", "pred_score_pos": 0.9963989853858948}
{"content": "Learn how the best companies achieve more by managing alignment directly.\nAligning your company is one of the highest ROI activities that you can do as a leader. Chances are, however, that alignment is not a top priority for your company (yet). Many leaders don't take alignment seriously at first because:\nUnfortunately, unaddressed misalignment is expensive and risky for all types of businesses. Here are a few of the impacts that misalignment has on businesses:\nIn short, misalignment is expensive. Misalignment causes companies to waste money on projects and unfocused activities. It causes them to struggle to differentiate themselves to customers. It also causes them to lose their best people and sometimes even behave in unethical ways. This all would be tragic if there was nothing we could to about misalignment.\nIf you're experiencing these issues, you're likely facing misalignment within your company.\nManaging alignment doesn't have to be expensive. Strong alignment can save your company money by increasing its focus. In tough times like these, survival depends on the ability to get more done with less.\nAlignment management is a new field of management that addresses the issue of alignment. In the past, managers have focused on managing tasks and projects, and not the links between them. This creates a problem: the wrong outputs do not lead to the right outcomes.\nIn fact, the Project Management Institute (“PMI”) has recognized this problem. They now include strategic alignment as a pillar of their new definition for success. This new definition supplements the traditional “time, cost, and scope\" factors for success. Yet, despite the PMI's new focus on strategic alignment, they are not prescriptive about its implementation.\nAlignment management works by treating your business as a value chain. Within that value chain, each piece gets aligned to the company's purpose and the rest of the value chain. Misaligned elements are then either course corrected or eliminated. This process is ongoing and cyclical, ensuring your business remains positioned for success.\nAlignment management provides a standard language and systematic approach for evaluating, measuring, and managing alignment. We do not prescribe specific best practices. Instead, we focus on an evidence-based approach to making decisions about alignment. These factors often include:\nAlignment management treats every organization as a value chain, with four categories of components that can be aligned.\nThese components are: people, structure, culture, and processes. Alignment managers play a crucial role in deciding the right mix for these components.\nAlignment management builds on years of research and practice in vast fields, including:\nThis research does not provide a set of best practices that companies can follow since every company is unique. Likewise, research into these disparate fields does not always result in consensus. There are many right solutions. We aim to distill the most important elements of alignment in an accessible format.\nIn addition to the alignable components of an organization, there are three factors of success for alignment management.\nThere is no one-size-fits-all approach to alignment or strategy. Instead, each business needs to select the right business and alignment strategy to fit their circumstances. Factors for determining fit include how well it fits the needs of customers and whether it fulfills the purpose of the company.\nStructure determines how strategy executed. The context people work in is a determining factor in deciding how they perform and how they'll make decisions. Structure includes communication lines, organizational architecture, formal processes, and technology used (IT).\nPeople are the driving force of progress within an organization. Every person comes to work with a different set of motivations. Some are extrinsic, such as pay, recognition, and career advancement. Others are intrinsic, such as fulfillment, enjoyment, and a sense of accomplishment.\nIncentives influence behavior. If incentives don't align with the purpose of the organization (or its values), then behavior will also be misaligned. At best, wrong incentives can lead to poor performance and wasted opportunities. At worst, they can lead to lawsuits and PR disasters.\nThe rest of this guide is dedicated to the Alignment Management Methodology (\"AMM\"). AMM is an opinionated approach to the problem of alignment. It provides a framework for many innovation-centric businesses to manage alignment.\nThe Alignment Management Methodology is not for every type of company. We recommend this methodology only for companies that meet the following criteria:\nOrganizations that are stable and unchanging have alternative tools for alignment. We recommend reading Align by Jonathan Trevor for ideas on how to align stable and change-averse businesses.\nYour organization’s purpose is enduring and perpetual; it rarely changes. By contrast, the rest of the value chain is constantly evolving. There are several reasons that a value chain may need to be adjusted, including:\nWe recommend every company have an alignment manager (or an Office of Alignment) that works directly with the executive team. This person supports the organization by ensuring each component of the company aligns. They ensure value eroding aspects of the organization are reduced or eliminated. They are responsible for increasing performance across the company through alignment.\nAligning an organization requires effective communication. The best strategy will create no value if it is not communicated on time. At the same time, the best of strategies align with reality. It's critical for functional managers and individual contributors to share their discoveries. Therefore, communication systems — and the silos that form around them — need to be in sync with your company’s alignment strategy.\nPoorly managed silos hamper an organization’s ability to perform and react to change. This is caused by the low mean response time for new information to be acted on. As a result, alignment managers should ensure teams remain between 3 and 7 people in size, following the 3-max-7 rule.\nSmaller teams are always more efficient, at the cost of lower total productivity. Teams greater than 7 people are exponentially less efficient. A 14 person team is 4.3x less efficient, despite only having 2x more people.\nWhile individual teams can remain under 7 people in size, projects often cannot. Projects regularly span tens and hundreds of people. This conflict of priorities create a paradox. How do we complete large projects without spending too much time communicating or creating silos?\nThis is where the Alignment Management Methodology helps.\nStart by creating the right context and architecture for aligned work to occur in. Alignment managers should work with individual teams to connect their execution to strategy. There are several tools they can use to create context, including:\nTo make this context actionable, capture this information in an accessible place. Don’t let this information live only in a few individual’s heads or in unstructured meeting minutes. Tools like Minsilo can help to improve the visibility of this context and connect it back to execution.\nAlignment Managers also are critical to bridging people in an organization. They can help foster psychological safety and connect disconnected teams. Google found psychological safety as the number one contributor to their teams’ performance. This supports research in the field of behavioral psychology on rapport and trust-building in enabling effective collaboration.\nPeople work better with people they know well. But, given the time investment required for rapport, Alignment Managers need to be strategic in how they connect people. There are a few ways to do this:\nWith the right approach, behavioral psychology can become a lever for organizational performance. Companies that master managing the way “people really work” dramatically outperform their competitors. They attract better talent, enable a growth mindset in their people, and improve employee engagement.\nImportantly, the best practices for creating and managing alignment are not universal, but some common practices should help get your people working effectively.\n\"Discipline equals freedom\" - Jocko Willink\nAccountability is essential to performance. A lack of accountability is the result of poor leadership and organizational architecture. Fortunately, there are ways to systematically improve accountability, such as:\nClear goals and accountability shift contributors from thinking about what they need to do to why it matters. They create a culture of leadership and ownership. Alignment managers play a consultative role with teams. They help them set goals and performance measures that align with the organization.\nIn this guide, we took an opinionated approach to the challenge of alignment. We attempt to only provide universally valuable practices, but leave much of the implementation decisions up to you.\nWe encourage you to carefully consider your organization’s own needs. Any alignment effort will fail if it’s not congruent with the needs of your business. You cannot execute another company’s alignment strategy, because it is not relevant to the context of your business. Alignment strategy must be tailored to your business’ needs, even if the tools and frameworks used are similar to other companies.\nMinsilo is designed from the ground up to provide a simple way for leaders to manage alignment. Connect day-to-day execution to company strategy, while shifting focus from output to outcomes.\nThese resources were instrumental in creating the methodology. We recommend checking them out.", "pred_label": "__label__POS", "pred_score_pos": 0.5285828113555908}
{"content": "Donald Rumsfeld had a knack for capturing the essence of uncertainty. The former US defence secretary, known for his taxonomy of known and unknown unknowns, was once quoted as saying the future was not necessarily less predictable than the past. “I think the past was not predictable when it started,” he said.\nThat was certainly true of the past 12 months. No year is free from surprises, but firms everywhere faced unprecedented lack of visibility in 2009, as debt markets remained frozen and equity markets boomeranged. Starved...", "pred_label": "__label__POS", "pred_score_pos": 0.6471418142318726}
{"content": "If you're a single homebuyer, financing, maintenance, your financial security, your lifestyle, and your future are important topics to consider.\nYour Future\nThings happen. Sometimes we change our minds. It's wise to think ahead and be prepared.\nThough you might not need much space now, how large must your home be? Is a big kitchen or the [...]", "pred_label": "__label__POS", "pred_score_pos": 0.8002312779426575}
{"content": "Neural networks are a plastic, dynamic architecture, a constellation of neurons that light up momentarily to perform a specific task. This is why, as you mull over a particular thought (good or bad) or practice a particular activity (beneficial or detrimental), you reinforce the neural networks that correlate with those thoughts and skills.", "pred_label": "__label__POS", "pred_score_pos": 0.9140864014625549}
{"content": "“The cannabinoid (CB) system is widespread in the central nervous system and is crucial for controlling a range of neurophysiological processes such as pain, appetite, and cognition. The endogenous CB molecules, anandamide, and 2-arachidonoyl glycerol, interact with the G-protein coupled CB receptors, CB(1) and CB(2).\nThese receptors are also targets for the phytocannabinoids isolated from the cannabis plant and synthetic CB receptor ligands.\nThe CB system is emerging as a key regulator of neuronal cell fate and is capable of conferring neuroprotection by the direct engagement of prosurvival pathways and the control of neurogenesis.\nMany neurological conditions feature a neurodegenerative component that is associated with excitotoxicity, oxidative stress, and neuroinflammation, and certain CB molecules have been demonstrated to inhibit these events to halt the progression of neurodegeneration.\nSuch properties are attractive in the development of new strategies to treat neurodegenerative conditions of diverse etiology, such as Alzheimer’s disease, multiple sclerosis, and cerebral ischemia.\nThis article will discuss the experimental and clinical evidence supporting a potential role for CB-based therapies in the treatment of certain neurological diseases that feature a neurodegenerative component.”", "pred_label": "__label__POS", "pred_score_pos": 0.9373757839202881}
{"content": "Construction equipment hire and services provider Speedy, has partnered with technology company Telent to deliver a low-carbon solution to help keep a major trainline running on the West Midlands Railway network.\nSpeedy provided an efficient hybrid-generator power source for a mobile transmitter required to fill a communications blackspot close to Sutton Coldfield station, while a permanent option was sought. Keeping communications flowing between train drivers and signallers is vital in ensuring rail networks can operate smoothly.\nThe transmitter required a low power load making it unsuitable for a standard generator package. Speedy sought a battery storage unit from supply partner Off-Grid Energy, which was used as the principle power source. This was paired with a 20kva diesel generator, which operated six to eight hours a weeks to recharge the battery storage unit.\nAs a result of the generator’s minimal running times, the fuel tank supplied allowed for eight months of 24/7 operation without the need for refuelling. The remote monitoring facility of the battery storage unit allowed Speedy to identify any power supply issues & implement resolutions before these became apparent to Telent.\nBetween July 2019 and January this year, 93 percent of the power supplied to the transmitted came from the battery storage unit, resulting in a carbon saving of almost 28,500 kg, with the remaining seven percent coming from the generator while working to recharge the battery.\nGreg Mawby, National Account Manager at Speedy, said: “The West Midlands Network plays a vital role in connecting millions of people across the region and ensuring a power solution was in place quickly ensured signalling communications remained open to maintain daily train services.\n“Product availability across our nationwide network means we can act immediately to meet our clients’ needs, while ensuring they have access to sustainable equipment to help cut carbon footprints across their projects. We were able to help Telent make a significant carbon saving, while cutting fuel costs by more than £250 per week.”\nFranc Volcansek, Senior Project Engineer at Telent, added: “Speedy provided us with an intelligent, cost effective and low-carbon power supply to keep the line operational. Our partnership with the business enables us to get the equipment we need at very short notice to consistently meet urgent deadlines on a network where we play a key role as a trusted partner of the rail operator. We look forward to working closely with the business as we continue to deliver a reliable and cost-effective service to the region.”", "pred_label": "__label__POS", "pred_score_pos": 0.8502764701843262}
{"content": "Child Maltreatment 2007, an annual report from the Children’s Bureau, is now available online. The report presents national and state statistics on child abuse and neglect derived from data collected by child protective services (CPS) agencies through the National Child Abuse and Neglect Data System.\nThis year’s report shows a decrease in the number of children who were maltreated—794,000 in 2007, which is down from 904,000 in 2006. The report includes information on:\nThe estimated 3.2 million referrals made to CPS agencies in 2007, involving the alleged maltreatment of approximately 5.8 million children; Fatalities that occurred as a result of maltreatment; Perpetrators of maltreatment; and Services to prevent maltreatment and to assist victims.", "pred_label": "__label__POS", "pred_score_pos": 0.8618626594543457}
{"content": "Food cravings are a natural process driven by biology and patterned behaviors. When it comes to living a naturally healthy life, recognizing these cravings and learning productive strategies for coping is essential. When we give into these cravings, it just rewards us and creates more cravings in the future. During this podcast, I discuss why we have food cravings and I introduce strategies for coping with cravings.", "pred_label": "__label__POS", "pred_score_pos": 0.9633529186248779}
{"content": "Abstract\nTo elucidate spatial assemblage patterns during 2 consecutive austral summer seasons, we sampled intensively the macrofauna from 73 stations located at the southern coast of Livingston Island. Representatives of 28 higher taxonomic groups were used for the faunal analysis. While two faunal descriptors (i.e. group richness and total biomass) changed markedly with increasing water depth, total density remained relatively constant. Sessile suspension-feeders belonging to the Ascidiacea and Porifera dominated at shallower depths (< 100 m) with a mean biomass (wet weight) estimate of 3,238 g m-2. In contrast, deeper faunal assemblages were dominated by deposit-feeding polychaetes with lower biomass values of 538 g m-2. Mean body mass for dominant groups reflected two contrasting trophic strategies: ascidians at shallower depths (< 100 m) attained a value of 6 g whereas a comparable density of polychaetes at deeper depths (> 100 m) obtained 0.37 g. This faunal discontinuity, primarily influenced by depth-related variables, is suggested to be directly related to food availability.", "pred_label": "__label__POS", "pred_score_pos": 0.9981794357299805}
{"content": "Abstract\n(-)-6-(7-Methoxy-2-(trifluoromethyl)pyrazolo[1,5-a]pyridin-4-yl)-5-methyl-4,5-dihydropyridazin-3(2H)-one (KCA-1490) exhibits moderate dual PDE3/4-inhibitory activity and promises as a combined bronchodilatory/anti-inflammatory agent. N-alkylation of the pyridazinone ring markedly enhances potency against PDE4 but suppresses PDE3 inhibition. Addition of a 6-aryl-4,5-dihydropyridazin-3(2H)-one extension to the N-alkyl group facilitates both enhancement of PDE4-inhibitory activity and restoration of potent PDE3 inhibition. Both dihydropyridazinone rings, in the core and extension, can be replaced by achiral 4,4-dimethylpyrazolone subunits and the core pyrazolopyridine by isosteric bicyclic heteroaromatics. In combination, these modifications afford potent dual PDE3/4 inhibitors that suppress histamine-induced bronchoconstriction in vivo and exhibit promising anti-inflammatory activity via intratracheal administration.", "pred_label": "__label__POS", "pred_score_pos": 0.901276171207428}
{"content": "Rare plant species are vulnerable to genetic erosion and inbreeding associated with small population size and isolation due to increasing fragmentation, though the degree to which these problems undermine population viability remains debated. We explore genetic and reproductive processes in the critically endangered long-lived tropical tree Medusagyne oppositifolia, an endemic to the Seychelles with a naturally patchy distribution. This species is failing to recruit in three of its four populations. We evaluate whether recruitment failure...\n1 citation reported since publication in 2011.", "pred_label": "__label__POS", "pred_score_pos": 0.9922449588775635}
{"content": "We are only beginning to understand the impact of the recently passed Tax Cuts and Jobs Act of 2017. Like all other reform measures, it promises to simplify the tax filing process. However, this will not necessarily be the case.\nRecent commentary discusses how this act will impact those who work remotely. While we have seen significant increases in the number of individuals who use their laptop to\nwork from home, these individuals may feel the impact of changes to the tax law.\nFor example, under the foreign earned income exclusion classified in Section 911 of the Internal Revenue Code, taxpayers are able to exclude a significant amount of income. This exclusion, however, requires that the taxpayer have their “tax home” in a foreign nation and not have an “abode” in the U.S.\nThere is little guidance pertaining to what a “tax home” and an “abode” actually is. This is only one area of confusion for taxpayers when it comes to changing tax regulations.\nStates may change their tax codes in response to the new federal tax act\nThe Tax Cuts and Jobs Act of 2017 does provide opportunities for certain individuals and businesses to reduce their tax obligations. However, even such a reduction can cause issues for taxpayers when it comes to filling out their state returns.\nAs states have historically modeled their tax codes after the\nInternal Revenue Code, states will continually need to reconsider whether they wish to continue conforming with the Internal Revenue Code in this manner. By continuing to model themselves after the federal code following passage of the new tax act, states could see reduced revenues.\nInstead of continuing to follow the federal code, states may change reporting requirements to make up for decreased revenues. Thus, any reduced tax obligations for individuals under the federal code could still mean individuals will pay more in state taxes.\nConfusion may mean taxpayers will require advice and guidance\nAs Michigan taxpayers need to abide by both the IRS code and state tax laws, they likely will need extensive guidance in filing their returns. Reporting may be more complex. Also, discrepancies in returns could lead to audits and penalties that taxpayers would otherwise wish to avoid.", "pred_label": "__label__POS", "pred_score_pos": 0.6192595958709717}
{"content": "Experts estimate that a quarter of a billion people are potentially on the brink of starvation.\nAt least 1 in 3 children under five – or over 200 million – is either undernourished or overweight, and the greatest burden of malnutrition in all its forms is shouldered by children and adolescents from the poorest and most marginalized communities.\nAt UMR, we use our agile resources and staffing to target our efforts in the regions where there has been least progress to end world hunger. These regions are often remote, rural, and/or chronically vulnerable by effect of conflict or natural disaster. Cultural norms are often strongest in these regions, which makes it difficult to reach hungry households. As such, UMR’s approach to household food security is based on two principles (a) cultural sensitivity, and (b) dignified household nourishment.", "pred_label": "__label__POS", "pred_score_pos": 0.6226892471313477}
{"content": "Sense of agency (SoA) is the subjective feeling that a person causes a change in the external world. The influence of SoA on crossmodal integration has not yet examined thoroughly. We investigated the effects of auditory stimuli on visual localization and its interaction with SoA. In Experiment 1, participants localized the disappearing position of a moving dot while hearing a continuous sound. The sound duration was manipulated. Participants performed the localization task after self-initiating the dot motion (higher SoA) or after the dot moving automatically (lower SoA). Results showed that localization of disappearing position of the dot was clearly manipulated by the sound duration, but auditory-based mislocalization was not influenced by the presence of action. In attempt to attenuate the reliability of visual signals for localization, we made visual stimuli flickered in Experiment 2. However, the results were similar to those of Experiment 1. Our study indicated that the presence of action (or SoA) might not influence auditory-visual integration. We discussed this possibility along with limitations of the present study.", "pred_label": "__label__POS", "pred_score_pos": 0.8901985287666321}
{"content": "Unlocking Hidden Value in Class B and C Office Buildings\nis the first study of its kind, offering guidance and strategies for implementing energy efficiency and green leasing measures specifically tailored to the owners and operators of Class B and C office buildings. Unlocking Hidden Value in Class B/C Office Buildings: Best Practices for Pursuing Low-Cost, High-Impact Energy Efficiency and Green Leasing Strategies\nCompared to their Class A counterparts, Class B and C office properties typically are older buildings with fewer technologies in place. While owners and operators of these properties are often eager to enact sustainability strategies, they can be constrained by smaller budgets, limited staffing and the high demand of day-to-day operational needs. As a result, Class B and C buildings often trail Class A buildings in adopting energy efficiency strategies and green leasing provisions. However, they also are the asset class with the most to gain from these measures. Per this report, these untapped sustainability opportunities have the potential to:\nReduce operating expenses for a Class B or C building by between $0.26 and $0.61 per square foot;\nIncrease net operating income (NOI) for Class B or C properties by between 2.4 percent and 5.6 percent per year; and\nBoost Class B or C property value by approximately $5 to $11 per square foot.\nThis research was supported with funding from BOMA International and Yardi and created in partnership with the Rocky Mountain Institute (RMI) and the Urban Land Institute (ULI).", "pred_label": "__label__POS", "pred_score_pos": 0.993851900100708}
{"content": "(Sept. 24, 2019) On July 11, 2019, the president of Ukraine signed into a law a bill on facilitating access to charging stations and requiring designated lanes for electric vehicles. (Law of Ukraine on Amendments to Some Legislative Acts of Ukraine on Creating Access to Charging Station Infrastructure for Electric Vehicles, July 11, 2019). The law enters into force on January 1, 2020.\nThe law amended the Code of Administrative Violations to establish fines of 20 to 30 times the gross minimum monthly incomes (about US$3,000 to $4,050) for stopping or parking nonelectric vehicles in parking spaces designated for vehicles with electric engines. The same fine applies for blocking or obstructing electric or hybrid cars from parking in such parking spaces. Nonelectric vehicles parked in such spaces that block traffic or threaten traffic safety can be towed or booted by law enforcement. (§ I(1), (2), (6).)\nUnder the new Law, the cabinet of ministers is responsible for drafting implementing legislation within six months from the date the law is officially published and for bringing existing legislation in compliance with current law. These changes will give drivers of electric vehicles approximately the same rights enjoyed by drivers with disabilities. The relevant ministries must also within six months provide for the introduction of new signs that reserve special lanes on roads and parking spaces for the use of electric vehicles. In addition, cars equipped with electric engines must be issued distinctive plates with green lettering within six months from the day the law is published. (§ II(2), (3).)\nUkraine’s government has already created a favorable tax and customs regime for importing and purchasing electric vehicles. Additionally, in December 2018, the State Energy Regulator determined that providing electric charging services is not considered supplying electricity and therefore does not require a license.\nStatistics indicate that Ukraine experienced a nearly 50% increase in primary registrations of electric cars in May 2019 compared to the previous year and that the network of charging stations is expanding rapidly as well.", "pred_label": "__label__POS", "pred_score_pos": 0.903649091720581}
{"content": "Customer Relationship Management (CRM) is a strategic tool which can help your business manage any correspondence and interactions made with a range of stakeholders within and outside your business. This can include a comprehensive view of interactions your company has with your customers, prospects and suppliers. Having an effective CRM system in place can facilitate an enhanced experience for your stakeholders. This is particularly important as a small business, as maintaining long-standing relationships with your stakeholders is crucial when securing repeat business.\nMany businesses, particularly SMEs, start their business with a physical list or book of contacts with their names and phone numbers, and would have typically stored this information and data in a document or a spreadsheet. If these customers or prospects were contacted, any correspondence that you'd had with them might have been written down or even typed up on separate document. This process is not only inefficient and frustrating for both parties, but it is ultimately not the most profitable way to run a business.\nIn order to remain competitive, SMEs need to think about how they can run their business more efficiently and effectively. Implementing a CRM system allows for any correspondence to be stored in one centralised database, and should be accessible to your entire team. Most CRM systems will allow you to choose what access you'd like to give each employee within the system, so you can ensure they're able to get to information that is relevant to their role or department.\nA CRM should give you business control through the full sales cycle - from Marketing, Sales Lead Management, Quoting, Ordering, After Sales Service, and Business Intelligence. We've outlined some examples below of how our solution, Prospect 365, can benefit key roles within all organisations:\nIntegration is what we do best. Find out more about what Integration involves here.Learn more about Accounts Integration\nThink a B2B Trade Portal is not for you?\nThink again!\nGetting your team on board with a new CRM is not easy, but it's imperative. Our Whitepaper explains why.Download here", "pred_label": "__label__POS", "pred_score_pos": 0.5126190185546875}
{"content": "A significant clinical insurance agency is a medical coverage organization that sells significant clinical protections – arrangements that give adaptable, reasonable inclusion for most wounds and sicknesses. Significant clinical protection plans spread most genuine clinical costs up to a greatest breaking point, typically after a deductible and co-protection arrangement.\nA significant clinical insurance agency for the most part offers two significant protection designs, the Managed care clinical plans and the reimbursement plans (conventional protection plans). In repayment plans, additionally alluded to as “repayment” designs, a back up plan repays the guaranteed for clinical charges regardless of who offered the assistance. Overseen care plans incorporate Health Maintenance Organizations (HMOs), Preferred Provider Organizations (PPOs), and Point of Service (POS) designs; all include an understanding between the back up plan and a chose gathering of clinical suppliers.\nBefore settling on a significant clinical insurance agency, it is insightful to do a cautious investigation of the plans just as a near investigation of the statements gave by the insurance agencies. Numerous protection specialists by one way\nAsuransi-kesehatanku or another “overlook” to discuss plan limitations, which could make the arrangement completely insufficient. Consequently, it is significant that one does some cautious examination before focusing in on an arrangement that is perfect for one’s family and that accommodates one’s tote.\nThe Internet is a rich wellspring of data with respect to organizations’ arrangements and administrations. Look at and break down the expense of each arrangement before coming to any end result. In the event that the statistical data points leave your head spinning, discover master counsel. Another choice is to reach significant clinical insurance agencies and get familiar with the advantages that you get at the cost that you have at the top of the priority list.\nSignificant clinical protection inclusion is likewise a commitment of the government wellbeing office. A rundown of organizations and operators dealing with protection inclusion is accessible at the express division’s office. Notwithstanding the organizations’ rundown, the workplaces give significant guidance on which strategy to pick just as data on organizations with unfavorable histories.", "pred_label": "__label__POS", "pred_score_pos": 0.6744132041931152}
{"content": "Following Jesus entails developing an intimate relationship with him. This is what elevates Christianity beyond all other religions, philosophies, and worldviews. Mark 3:14-15 says, ‘He appointed the twelve—designating them as apostles, that they might be with him and that he might send them out to preach and to have authority over demons’.\nA closer look at this Scripture—‘that they might be with him’—reveals that endeavouring to do anything for Jesus is linked with desiring and developing a relationship with him.\nChristianity in general and discipleship in particular is based on a relationship with Jesus, not on spiritual directions and rules. Once we decide to let him have control over our lives, he will show us the way and teach us. This entails all the directions we need as we deepen our relationship with him.\nIsaiah M. Dau(excerpt) Lausanne Movement", "pred_label": "__label__POS", "pred_score_pos": 0.7494375705718994}
{"content": "Q: Dear Dr. Mao,I used to eat all the right foods: yams, pumpkin soup, parsley, cilantro, green leafy vegetables, and almonds. Then I got a kidney stone. All the foods that have been called healthy are now supposedly unhealthy. What are your thoughts on this? A: It is true that some of these foods in high concentrations and under specific conditions may cause kidney stones. However, ruling out any serious conditions with the kidneys or congenital conditions, I believe the cause for stone formation is probably due to lack of sufficient water intake. You need at least 80 ounces of fluids per day to properly flush out the kidneys.\nAlso, some people tend to overdo supplementation, which can overbuild calcium deposits in the system if not flushed properly. I would suggest first increasing your water intake. Then, moderate these foods and consume a more balanced diet. You should also include fish or other omega-rich foods.\nThere are specific treatment protocols for stones within traditional Chinese medicine (TCM); you might consult a licensed acupuncturist/herbalist to discuss these options.", "pred_label": "__label__POS", "pred_score_pos": 0.6105929613113403}
{"content": "Sponges are considered poor invaders, and no genetic studies on introduced sponges have been performed up to now. Paraleucilla magna is the first calcareous sponge introduced to the Mediterranean and Northeastern Atlantic. The study aimed at investigating the genetic makeup and connectivity of the introduced populations of P. magna and at exploring signs of local phenotypic adaptation, to gain insight on the species invasive potential. Ten populations along the species introduction range (Brazil, Açores, Madeira, and continental Europe) were genetically characterized by using nine microsatellite markers. Most populations were genetically structured as suggested by significant Dst and Fst values, significant differences among populations (AMOVA) and the presence of private alleles. The analyzed populations belonged to three genetically homogeneous groups (K) according to the Bayesian algorithm (structure software) and the UPGMA dendrogram. Genetic diversity within populations was higher than expected. Recurrent introductions of non-randomly selected individuals from the native sources may have contributed to the heterozygote deficit found in all populations by forming pedigree structures with mating among relatives. Moreover, the species biological cycle was monitored in a population established on native Mediterranean assemblages (41°40′27″N, 2°47′25″E) and compared with the species cycle in other habitats. Contrasting life spans, growth habits, and reproduction cycles, depending on the habitat conditions, were recorded. To summarize, high genetic diversity, phenotypic local adaptation, and high reproduction rates altogether allow predicting the fast proliferation of P. magna in newly colonized regions and point to its strong invasive potential.", "pred_label": "__label__POS", "pred_score_pos": 0.5833344459533691}
{"content": "Please watch Germfree’s video featuring a recent project where we delivered a BSL-3 laboratory to East Asia and made the bio-containment lab operational in only 21 days.\nThis Biological Safety Level 3 (BSL-3) modular laboratory was manufactured by GERMFREE in the U.S. and then installed in East Asia.\nIn this video:\nGermfree presents a truly unique approach to bringing advanced high containment laboratories to wherever they are needed… anywhere in the world.\nGermfree designs, engineers and manufactures Biological Safety Level 3 (BSL-3) laboratories in our U.S. facility.\nThese containerized modular labs are then delivered and installed in locations across all continents.\nAfter manufacture, the lab is transported as containerized units to be reassembled at the site. This method makes easy global deployment a new possibility for high containment labs.\nBSL-3 labs require a range of critical steps after completion of construction and prior to laboratory operation. These processes traditionally take 6 months to over a year. This Germfree project took just 21 days from on-site setup to meeting all operational requirements, making the BSL-3 lab ready for use.\nWith Germfree’s advances in biosafety engineering and manufacturing, high containment laboratories can now become operational in an unprecedented time frame.", "pred_label": "__label__POS", "pred_score_pos": 0.7537360191345215}
{"content": "SME’s being held back by lack of funding\n20/08/2019\nA study by Aldermore Future Attitudes has shown that just under a fifth of UK SME’s have missed out on a new lucrative opportunity in the last 12 months due to a lack of available funding.\nEach year, these missed opportunities are said to be leading to businesses losing out on an average of £76,888 income.\nThe new information highlights the impact of small businesses not being able to access the necessary funding they need to grow and seize new opportunities.\nThe survey was conducted with over a thousand business decision makers across the UK and found that while 19% of SME’s in total were held back by a lack of funding, the number jumped up to 28% when looking at medium sized businesses alone.\nFor business based in London, the average income lost was a staggering £135,791 annually.\nImplications\nAs well as the direct financial implications, other issues stem from a lack of funding, such as not being able to achieve business objectives. 37% of SME’s cited achieving growth as their number one objective, with a further 24% prioritising developing and expanding their products and services. 21% are focusing on expanding in the UK.\nFor businesses trying to innovate and grow, cash flow and available funds have become a major concern. 25% of SME’s stated cash flow was their biggest concern in the next 12 months, while 12% feel that keeping up with technology is highest on their list of potential problems.\nThe research demonstrates the importance for businesses to have the right funding behind them, which provides the flexibility to seize such opportunities as they arise.\nFor small businesses, finding the right funding doesn’t need to be daunting, and you needn’t think your options are going to be limited due to your size. As a commercial finance broker helping business of different sizes across the UK, Hilton-Baird Financial Solutions can help.\nWe can assist you in comparing the many funding options available for small businesses, find a facility that aligns with your business goals and support you through your funding application.\nGive us a call on 0800 9774833 to see how the right funding solution can abate all your cash flow worries!", "pred_label": "__label__POS", "pred_score_pos": 0.611531138420105}
{"content": "Tobacco is one of the most common and preferred forms of addiction. Even though scientific evidences have revealed its harmful health effects the use of tobacco in different forms has seen a dramatic increase especially in the developing countries. This potentially lethal substance is responsible for more than 1 in 10[1] fatalities globally with India featuring among the top four users of tobacco.About 11.2% smokers worldwideare Indian. Despite decades of research and strong initiatives for controlling diabetes carried out globally the number of tobacco users in the world has not seen a declining trend. Tobacco has been used extensively for", "pred_label": "__label__POS", "pred_score_pos": 0.9995489120483398}
{"content": "Having recently completed its network refresh to 100 Gps port capabilities, the Malaysia Internet Exchange (MyIX) is now in the process of opening two new nodes for more networks to join its internet exchange.\nAccording to MyIX chairman Chiew Kok Hin, these new nodes serve to extend MyIX’s reach while increasing its presence points throughout the country.\nCurrently, MyIX operates two additional nodes which are located in Iskandar Puteri, Johor and Kuching, Sarawak to complement the main nodes located at the AIMS Data Centre and CSF Building in Cyberjaya, Selangor.\nThese two new nodes are set to be opened in two locations in Cyberjaya next month, and in April, respectively. These will be operated in partnership with IPSERVERONE SOLUTIONS SDN BHD and VADS BHD.\nThese nodes are essentially access switches located at various alternative sites; thereby enabling members and peering partners to connect to internet service providers (ISPs), other members and content hosted by MyIX.\nChiew explained that, since ISPs and content distribution networks (CDNs) are spread across various data centres, these nodes serve to provide additional exchange points for ISPs and CDNs to better connect with one another, especially useful when connecting from remote locations.\n“The nodes also ensure improved latency for interconnectivity with other networks,” he added. “They would be instrumental in further enhancing the stability and performance of internet connections, lowering connection costs while minimising traffic ‘bottlenecks’.”\nMyIX is an initiative under the Malaysian Communications Multimedia Commission (MCMC). Today, MyIX is the country’s only non-profit national internet exchange body operated by industry.\n“Due to Malaysia’s fast growing digital economy, there is now greater demand for faster and more reliable internet traffic performance,” said Chiew.\nAnd since MyIX facilitates to keep the domestic internet traffic within Malaysia, data always travels through the most optimised route to the end user. This results in improved broadband service quality for ISPs, which translates into a better experience for end users when they access local content.\n“Data also travels at an optimised distance with fewer ‘hops’ to reach the intended recipient through direct peering with MyIX. This poses a significant cost benefit for smaller ISPs, which can reduce their dependency on costly international bandwidth links,” explained Chiew.\nChiew is also encouraging international ISPs and CDNs to invest further in Malaysia.\n“By having foreign ISPs and CDNs setting their regional networks here, it will reduce the network charges of consuming international content,” he concluded.", "pred_label": "__label__POS", "pred_score_pos": 0.9634934067726135}
{"content": "This study by PTIN member Judi Perry provides new insights in the offering of 'unconditional positive regard'. The aims of the study were:\nFive semi-structured interviews were held with PCE Pre-Therapy practitioners from a range of countries and professional settings, utilising a descriptive phenomenological method to analyse\nthis data. Three main categories were discovered: theoretical, philosophical and experiential, with six sub-themes. These were then turned into an exhaustive description of the lived experience of PCE Pre-Therapy practitioners offering UPR to clients experiencing psychotic processes.\nPerry, J. (2019).\nRadical Acceptance. How do Person-Centred and Experiential Pre-Therapy practitioners experience offering unconditional positive regard to clients experiencing psychotic processes? A phenomenological study utilising the Duquesne method. Unpublished manuscript: Staffordshire University, The Sherwood Psychotherapy Training Institute. [Person-Centred & Experiential Psychotherapy – Postgraduate Programme] Available from: http://www.pre-therapy.com/Judi%20Perry%20Pre-Therapy%20Research%20-%20Radical%20Acceptance.pdf\nNews >", "pred_label": "__label__POS", "pred_score_pos": 0.996076762676239}
{"content": "Before the COVID-19 crisis, Kwintes successfully engaged their employee base in a structured innovation process powered by edison365. Through their Innovation Lab, they were able to gather ideas from the people who interacted with patients daily, discovering innovative ways to continue providing best-in-class care with ever restricting budgets.\nCrisis is often a trigger for innovation as traditional solutions are no longer viable; closed loop and point in time methods such as email threads, hackathons and surveys cannot support the necessary drive for innovation when employees are external stakeholders work remotely.\nUnderstand how edison365ideas and Open Innovation enable you to pose challenges, submit ideas, vote and review submissions from both your internal employees and external stakeholders, creating engagement across your entire ecosystem.", "pred_label": "__label__POS", "pred_score_pos": 0.6564074754714966}
{"content": "Political systems\nThese pages explore the theme of 'political systems', one of the 7 governance capabilities outlined in DFID's Governance Target Strategy Paper, 'Making Government Work for Poor People' as being key to poverty reduction.\nDFID's approach emphasises the importance of responsive and accountable government, ensuring that everyone, including poor people, enjoy all human rights. It also stresses the importance of access to free and fair elections and to information and representation for all people, including the poor, so that they can make informed choices and participate effectively.", "pred_label": "__label__POS", "pred_score_pos": 0.9991909861564636}
{"content": "The Labour Force Survey (LFS), conducted by Statistics Canada, is the source of monthly employment estimates for Canadian industries. The monthly LFS sample size is approximately 56,000 households, covering 100,000 individuals.\nTourism HR Canada receives customized LFS tables that follow the Tourism Satellite Account’s definition of tourism. This allows Tourism HR Canada to track employment and unemployment in the tourism sector and compare it with the overall economy.\nThis customized LFS data, publicly available LFS data, and other data sources on Gross Domestic Product (GDP) and mobility were used to develop the following month-by-month charts that track the impact of COVID-19 on Canada’s tourism sector. In addition to this ongoing tracking, we summarize the key points each month:", "pred_label": "__label__POS", "pred_score_pos": 0.8841946125030518}
{"content": "Abstract\nEstimation of parameters is a pivotal task throughout science and technology. The quantum Cramér-Rao bound provides a fundamental limit of precision allowed to be achieved under quantum theory. For closed quantum systems, it has been shown how the estimation precision depends on the underlying dynamics. Here, we propose a general formulation for metrology scenarios in open quantum systems, aiming to relate the precision more directly to properties of the underlying dynamics. This feature may be employed to enhance an estimation precision, e.g., by quantum control techniques. Specifically, we derive a Cramér-Rao bound for a fairly large class of open system dynamics, which is governed by a (time-dependent) dynamical semigroup map. We illustrate the utility of this scenario through three examples.", "pred_label": "__label__POS", "pred_score_pos": 0.9993613362312317}
{"content": "Linking maternal mortality files to violent death reporting system reveals more pregnancy-associated suicides, homicides\nA recent study co-authored by Anna Austin, doctoral student of maternal and child health, and Dr. Catherine Vladutiu, Gillings School alumna and adjunct faculty member in epidemiology, revealed that violent deaths occurring during pregnancy and up to one year postpartum are under-reported. Linking traditional maternal mortality surveillance system records with the North Carolina Violent Death Reporting System captured 55.6 percent more pregnancy-associated violent deaths than traditional surveillance alone.", "pred_label": "__label__POS", "pred_score_pos": 0.7363839149475098}
{"content": "Personal Independent Payments (PIPs) can help with some of the extra costs of personal care or mobility due to a long-term illness or disability. They have replaced the DLA and are being phased for anyone aged 68 or younger in 2015, so many parents may still be receiving DLA. PIPs are needs based and not dependent upon income/savings. There are 2 elements to a DLA/PIP:\nDaily Living component – claimants are assessed on things like ability to prepare food and drink, wash, dress, go to the toilet, manage health conditions and make financial decisions. The standard rate (2016) is £55.10 a week and the enhanced rate is £87.65 a week. Mobility component – claimants are assessed on their ability to plan and follow a journey and move around. The standard rate (2019/20) is £23.20 a week and the enhanced rate is £61.20 a week). Applicants will be assessed, and can be eligible to receive both elements. To apply, you need to contact the Department of Work and Pensions on 0800 917 2222.", "pred_label": "__label__POS", "pred_score_pos": 0.5347580909729004}
{"content": "Silverfish thrive in damp conditions, particularly bathrooms and kitchens. They like dark unfrequented places where they will be undisturbed and are attracted by sweet sugary substances. They can often be seen scurrying away when you switch on a light in a dark room.\nSilverfish Killer Sprays\nWe stock a range of insecticidal silverfish killer sprays which can be used directed onto ones that are visible and also around skirting boards, around cupboards and other commonly infested areas. The long lasting residue is very effective at controlling Silverfish once it’s dry.\nSilverfish Killer Powders\nSilverfish killer powders are perfect for sprinkling into cracks and crevices and reaching inaccessible areas such as under cupboards, skirting boards and other areas. The powder will cut into the cuticle of the silverfish and absorb the body moisture resulting in dehydration and death.", "pred_label": "__label__POS", "pred_score_pos": 0.7563279271125793}
{"content": "Prof. Adrian Hill, Founder-Director of the University of Oxford’s Jenner Institute is upbeat about the possibility of gathering emergency approvals for their COVID-19 vaccine candidate before Christmas.\nProf. Hill expressed that the coronavirus vaccine being developed by the University of Oxford, in collaboration with UK-based drugmaker AstraZeneca, is likely to be developed and administered to healthcare workers and high-risk individuals before the end of 2020.\nThe professor observed that even though the timing was tight to begin vaccinations against COVID-19 before Christmas, it was possible.\n“We’re looking for this year is an ’emergency use’ authorization that will allow us to go and vaccinate those most at risk as a priority, then early next year everybody else,” remarked Prof. Hill.\nAn emergency approval will allow individuals who have the highest risk against the pandemic to receive the vaccine even as the final trials of the vaccine are still underway.\nIf an emergency approval is gathered by the team by Christmas, there could be a remote possibility of having vaccination drives to the general public by early 2021.\nThe AstraZeneca-Oxford vaccine candidate is seen as a frontrunner in the race to produce a vaccine to protect against COVID-19.\nAfter its successful Phase 1 and Phase 2 trials which established that it is safe and triggers a strong immune response, the vaccine is currently in an advanced stage of its Phase 3 trials.\nFindings from a recent study revealed the vaccine produced a robust immune response in elderly people.\nProf. Hill remarked that an AstraZeneca-led consortium has already produced ‘billions of doses’ of the vaccine at ten factories across the world.", "pred_label": "__label__POS", "pred_score_pos": 0.6758729815483093}
{"content": "According to the Canadian Centre for Occupational Health and Safety, an estimated 60% of confined space entry fatalities have been among the would-be rescuers. A would-be rescuer is a person who is trying to help someone who has become unresponsive in a confined space. We sat down with gas detection training specialist Mike Platek to understand atmospheric hazards in confined spaces and how to prepare for potentially dangerous entries or rescues.\nSafetyDecisions_ConfSpac_Platek_April19.pdf", "pred_label": "__label__POS", "pred_score_pos": 0.969199538230896}
{"content": "The Building Division has implemented an expedited solar-permitting process for ≤10 kW systems. We will create a solar PV brochure to inform and assist with the permitting of PV systems for our unique mountain microclimate.\nThis information tracks the estimated electricity production capacity, or power rating in kilowatts DC, of solar photovoltaic installations town-wide.\nRenewable energy systems can include solar photovoltaic, hydropower, and wind power systems.\nRenewable electricity generated at the point-of-use offsets the need for utility-generated electricity. Currently, Truckee’s utility-generated electricity includes a mix of both renewable and non-renewable sources.\nThis information is source from Town building permits for photovoltaic installations.", "pred_label": "__label__POS", "pred_score_pos": 0.9994152188301086}
{"content": "British economist Nicholas Stern explains why setting a carbon price is key to fighting global warming. Carbon pricing has become central to this fight. Can you explain why?\nIt is crucial that markets provide a signal about costs if they are to guide economic action in positive ways, leading to the efficient allocation of resources. This means that the prices of goods, services and activities should reflect their real costs, including the costs they impose on others through the damages that they cause. By ensuring that the prices of fossil fuels reflect their true costs, policymakers help markets to operate more effectively. Carbon pricing is a pro-market action, and those who oppose it are anti-markets. The costs of climate change are potentially very large, and calculations of the social cost of carbon should reflect impacts across the world and on future generations, who could be impoverished by our failure to act.\n⇒ Read the full interview on The Conversation", "pred_label": "__label__POS", "pred_score_pos": 0.9853886365890503}
{"content": "Do you suffer from Anxiety, Depression, Lethargy, Anger, Loss, Resentment, Low Energy, Lack of Motivation or Stress?\nWould you like to take control of your emotional wellbeing?\nIf you are challenged by any of the above ….We CAN HELP\nEmotional Aromatherapy\nPsychology Meets Chemistry\nScientists and psychologists have spent centuries trying to understand the phenomena we refer to as emotions. Although science cannot yet definitively explain the exact mechanisms, we do know that emotions have vast influence on many components of well-being\nEmploying the most current research and the purest essential oils, the new Emotional Aromatherapy System is the first in the industry to offer scientifically formulated blends for comprehensive, robust, and targeted emotional health benefits.\nThe easiest way to experience essential oils is aromatically, by utilizing our sense of smell. Due to the amazing olfactory receptors, which identify odors and initiate the aromatic pathway, diffusing or directly inhaling essential oils is the most rapid and intense way to experience their influence on emotions 😗\nUse of our Emotional Aromatherapy System is predicated upon the oils unique chemical profiles. Based on known benefits of specific chemical constituents, categories of essential oils can be established. Each essential oil group has specific constituent profiles known to elicit distinct emotional responses.\nFloral essential oils are composed primarily of monoterpene alcohols, which exhibit toning and calming properties.\nTree, herb, and grass essential oils are rich in sesquiterpenes, esters, and oxides, which are grounding, soothing, and renewing.\nOn the other end of the spectrum, mint, citrus, and spice essential oils provide powerfully uplifting benefits. Mint essential oils have high concentrations of ketones, which are energizing and uplifting.\nCitrus oils are generally composed of limonene and beta-pinene, monoterpenes with strong uplifting characteristics. Phenols, the primary chemical constituents of many spice essential oils, are recognized for their warming properties.\n🌿 🌿 🌿 💧 💧 💧 🌱 🌱\nCombining CPTG oils in precise ratios, the emotional aromatherapy blends establish a new, complete, and unique spectrum of emotional benefits. For ease of use, included in the kit is an instructional diagram that breaks down these categories.\nThe Emotional Aromatherapy System is based on chemistry. Beginning with a specific chemical profile, the blends were put together based on the known properties of their chemical constituents as opposed to simply providing a pleasant aroma. The blending of these specific essential oils has created a synergistic composition ideal to promoting healthy emotional responses.\nMotivate Encouraging Blend\nThis is a wonderful combination of several citrus and mint essential oils, including Yuzu, Clementine, and Peppermint. This blend marks doTERRA’s first use of Yuzu, the limonene-rich essential oil expressed from the peel of the mandarin-like Japanese fruit. The resulting chemical profile is high in monoterpenes and monoterpene alcohols, which are known for their uplifting and toning properties.\nMotivate is the perfect aromatic compliment to help promote feelings of confidence when working on an important project. Cheer Uplifting Blend\nThis is an invigorating mixture of citrus and spice essential oils. Featuring Wild Orange, Cinnamon Bark, and Star Anise essential oils, the resulting chemical profile is rich in monoterpene and aldehydes, renowned for their uplifting and warming properties. Comprised almost entirely of the phenylpropene anethole, Star Anise essential oil brings potent energizing characteristics to the new blend.\nApply one drop of\ndoTERRA Cheer to your hands, rub together, and inhale deeply to help incite feelings of optimism. Passion Inspiring Blend\nThis balances spice and herbal essential oils. Included in the blend is Damiana, a very rare essential oil rich in 1,8-cineole and alpha pinene, which is renowned for its renewing properties. Combining Cinnamon Bark, Ginger, Cardamom, Clove, and Damiana creates a chemical profile with high concentrations of phenols and ethers to provide warming and renewing benefits.\nDiffuse doTERRA Passion at your work desk to help spark creativity.\nForgive Renewing Blend\nThis mixes familiar tree and herb essential oils to create a diverse chemical profile with high concentrations of monoterpene esters, alcohols, and sesquiterpenes. Most interesting is the introduction of Nootka Tree Wood, an essential oil with a very diverse chemistry composed primarily of soothing and grounding sesquiterpenes. Nootka Tree Oil is known largely for balancing emotions in stressful situations. Pure Thyme essential oil balances out the blend with potent renewing and toning properties.\nNo meditation session is complete without diffusing doTERRA Forgive to help encourage patience and contentment.\nConsole Comforting Blend\nThis combines floral and tree essential oils. The combination of Rose absolute, Ylang Ylang, Frankincense, Sandalwood, and several other highly valued tree and flower essential oils creates a blend rich in both monoterpenes and sesquiterpene alcohols. Labdanum absolute provides a number of interesting characteristics to the blend. High in alpha-pinene, Labdanum is highly renewing and its distinctive aroma is prized for its ability to balance competing scents. The final product mirrors its chemical structure and aromatic profile, being highly grounding and renewing.\nA drop or two of Console on your shirt collar can be that little extra you need to help counteract feelings of grief and sadness.\nPeace Reassuring Blend\nThis is a fusion of floral and mint essential oils. The union of popular essential oils such as Lavender and Spearmint, along with the essence of some lesser-known plants such as Labdanum, creates a chemical profile rich in monoterpene esters and alcohols for a renewing and toning experience. The resulting aromatic profile is calming and promotes feelings of peace and reassurance.\nDiffuse Peace at night to help promote the calming and restful sleep environment that you need to embrace the next day.\nDiscover for yourself how these unique blends can help you balance your moods and take charge of your own emotional well-being.\nIf you like to purchase this kit you can do so\nhere.", "pred_label": "__label__POS", "pred_score_pos": 0.6709983348846436}
{"content": "Mindfulness-Based (MBCT) Counsellors\nFor clients in Calgary with chronic pain, hypertension, heart disease, cancer, and other health issues such as anxiety and depression, mindfulness-based cognitive therapy, or MBCT, is a two-part therapy that aims to reduce stress, manage pain, and embrace the freedom to respond to situations by choice. MCBT blends two disciplines--cognitive therapy and mindfulness. Mindfulness helps by reflecting on moments and thoughts without passing judgment. MBCT clients pay close attention to their feelings to reach an objective mindset, thus viewing and combating life's unpleasant occurrences.\nMindfulness Based counsellors in Calgary can help with issues like anxiety and depression in their role as Calgary MBCT counsellors.\nHow can I tell if a therapist is right for me?\nTherapists in Calgary are able to work with a wide range of issues.\nFor example, if you're seeking a marriage counsellor in Calgary you'll find that most therapists are trained in marriage counselling or couples counselling in Calgary and couples therapy. And they welcome families for family counselling in Calgary or family therapy in Calgary.", "pred_label": "__label__POS", "pred_score_pos": 0.7769495844841003}
{"content": "Etiological Structure and In Vitro Susceptibility to Antimicrobial Agents from Blood Cultures in Bulgarian Multi profile Hospital, 2015-2016\nDuring the period 2015-2016, a total of 1490 haemocultures were tested, 24.4% of which were positive. Among the 363 isolated microbial agents, 224 (62% or 15% of all) were considered clinically significant with equal distribution of Gram-positive (48.2%) and Gram-negative bacteria (47.8%). This finding differs from European\nand US practice where Gram positive bacteria are dominant. Fungi were isolated in 4%. The etiological structure was as follows:Coagulase Negative Staphylococcus – 20.1%, E. coli - 14.3%, Enterococcus spp. - 14.3%, Klebsiella spp. - 11.2%, S. aureus - 10.3%, Acinetobacter baumannii - 9.4%, Enterobacter spp. - 5.8%, P. aeruginosa – 4.9%. A trend toward increase of Klebsiella spp, E.coli, S. aureus и Candida spp. and decrease of coagulase-negative Staphylococci, Enterococcus spp. and Acinetobacter baumannii was observed. Regarding “ESKAPE” pathogens – we had a similar rate of Enterococci, and lower rates for the rest compared to USA practice, but in contrast to European data we had lower rate of S. aureus, similar rates of Enterobacter and P. aeruginosa, and higher rates of Enterococci, Klebsiella and Acinetobacter. Multidrug resistance was found in 11% of Gram positive and 47% of Gram negative flora. Resistance rates were similar to the European, but higher in Gram negative and lower in Gram positive when compared to USA. Owing to failure of the other approaches we introduced a stronger stewardship and restrictive policy regarding prescription of antibiotics.", "pred_label": "__label__POS", "pred_score_pos": 0.9968469738960266}
{"content": "Single-Subject Designs: Procedures that Allow School Psychologists to Contribute to the Intervention Evaluation and Validation Process\nLike many undergraduate psychology students, I received training in traditional social science research (i.e., group-design and analysis procedures) and was required to conduct a scientific study using such procedures. I conducted an experiment in a laboratory setting where I manipulated tones and measured the effects on time perception of undergraduate students. The laboratory setting made it easy to control confounding variables, and technical equipment allowed for precise manipulation of the independent variable and measurement of the dependent variable. This experience was invaluable in that it allowed me, the researcher, to gain experience in the scientific process of evaluating cause-and-effect relationships. However, the same cannot be said for the undergraduate students who served as subjects for my experiment.\nWhile I cannot be certain, I would venture that none of my participants ever engaged in any life experiences that were enhanced because of their participation in this study. Even had I targeted a useful or functional behavior, the participants would have derived little benefit from the study as the goal was not to evaluate the effects of an intervention design to enhance their skills or ability in estimating time.", "pred_label": "__label__POS", "pred_score_pos": 0.7273385524749756}
{"content": "We describe the application of ethnography and experimentation to the specification and evaluation of a browser to support collaborative sharing of photographs in family contexts. In an extension of this mixed-method approach, we adopted an ethnographic stance to the posthoc analysis of couples’ interactions recorded during the experimental studies. The experiments and post-experiment analyses yielded usability enhancements and unexpected interaction patterns among couples in categorising and retrieving photographs that led to browser redesign.", "pred_label": "__label__POS", "pred_score_pos": 0.9098668098449707}
{"content": "More and more plastic products are being labelled as compostable, biodegradable, oxo-degradable or bio-based. However, plastics made from bio-based materials are not necessarily compostable or biodegradable. Moreover, plastics that do biodegrade can be made from fossil fuel-based materials.\nWhat is the difference between compostable and biodegradable? What happens to biodegradable and compostable plastics when they are littered? Can citizens compost such products in their own gardens? Can such plastics be recycled?\nThis European Environment Agency (EEA) briefing aims to answer these questions.", "pred_label": "__label__POS", "pred_score_pos": 0.7811073660850525}
{"content": "Promoting healing, enabling reconciliation and cultivating transformation in countries affected by mass violence remains a pressing question facing the global community. This class will explore the effects of collective violence, such as genocide, ethnic, inter- and intra-state conflict, and the recovery process. Focus will be on understanding the concepts of trauma and resiliency and exploring mechanisms for healing, fostering reconciliation, and transforming the trauma of war at multiple levels of analysis. Students will become familiar with current conceptual frameworks in the fields of trauma studies, social and political psychology, and international development related to these topics. Both historical and current cases of collective violence will be used to consider the effects of violence and the healing process at social, communal, and individual levels. Students will gain familiarity with and consider the challenges to and effectiveness of healing, reconciliation, and transformation processes that have been undertaken in post-conflict countries.", "pred_label": "__label__POS", "pred_score_pos": 0.9773275256156921}
{"content": "You don't know where your limits are until you start taking action.\nNot any action, but\nmassive action, the one that forces you to get outside your comfort zone, the one that scares the crap out of you. You know, that BIG action you're supposed to be taking on your dreams now instead of hanging out online.\nThe massive action will put you face to face with your fears, your blocks and your limitations.\nHow will you recognize them?\nYou'll feel resistance.\nYou'll start avoiding taking the action.\nYou'll come up with excuses.\nI'll do it this evening. I'll do it tomorrow. I'll do it next week.\nThis is resistance and it's coming up because you're hitting your own self-imposed limitations on things you can do and how much you can achieve, and fears about what'll happen if it doesn't work out.\nDon't run away from these fears. Don't shut them down. Don't ignore them. Don't switch on Netflix.\nInstead, look at each of these fears and beliefs with curiosity and ask yourself:\nWhat am I afraid of? What do I need to learn here? Why am I resisting doing what I need to be doing?\nJournal, meditate, talk to a friend, talk to a coach... You need someone to hold up a mirror to you and help you unearth your limitations. Once you recognize your limiting beliefs and process them, they will not have the power over you anymore and you'll get closer to living in alignment with your authentic integrity.\nIf you need help, I'll be happy to chat. You can book a clarity call with me at absolutely no charge and get help right away. I'd be happy to help!", "pred_label": "__label__POS", "pred_score_pos": 0.9207395911216736}
{"content": "Fashion is a language. How we dress signals to others who we are and how we want to be perceived. However, this language is primarily visual, making it inaccessible to people with vision impairments. Someone who is low-vision or completely blind cannot see what others are wearing or readily know what constitutes the norms and extremes of fashion, but most everyone they encounter can see and judgetheir fashion choices. We describe our findings of a diary study with people with vision impairments that revealed the many accessibility barriers fashion presents, and how an online survey revealed that clothing decisions are often made collaboratively, regardless of visual ability. Based on these findings, we identified a need for a collaborative and real-time environment for fashion advice. We have tested the feasibility of providing this advice through crowdsourcing using VizWiz, a mobile phone application where participants receive nearly real-time answers to visual questions. Our pilot study results show that this application has the potential to address a great need within the blind community, but remaining challenges include improving photo capture and assembling a set of crowd workers with the requisite expertise. More broadly our research highlights the feasibility of using crowdsourcing for subjective, opinion-based advice.", "pred_label": "__label__POS", "pred_score_pos": 0.9854328036308289}
{"content": "The MtENOD11 gene from the model legume Medicago truncatula is transcriptionally activated both in response to Sinorhizobium meliloti Nod factors and throughout infection of root tissues by the nitrogen-fixing microsymbiont. To identify the regulatory sequences involved in symbiosis-related MtENOD11 expression, a series of promoter deletions driving the beta-glucuronidase reporter gene were analyzed in transgenic M. truncatula roots. These studies have revealed that distinct regulatory regions are involved in infection-related MtENOD11 expression compared with preinfection (Nod factor-mediated) expression. In particular, the 257-bp promoter sequence immediately upstream from the start codon is sufficient for infection-related expression, but is unable to drive gene transcription in response to the Nod factor elicitor. This truncated promoter is also sufficient to confer MtENOD11 expression during both the arbuscular mycorrhizal (AM) association and the parasitic interaction with root-knot nematodes. Site-directed mutagenesis further showed that a previously identified nodule-specific AT-rich motif is required for high-level MtENOD11 expression during S. meliloti infection as well as during AM colonization. However, mutation of this motif does not affect gene expression associated with nematode-feeding sites. Taken together, these results suggest a close link between regulatory mechanisms controlling transcriptional early nodulin gene activation during both rhizobial and AM root endosymbioses.", "pred_label": "__label__POS", "pred_score_pos": 0.8301035761833191}
{"content": "Abstract\nUnderpinned by the findings of Jamieson and Harkins (2007; Experiment 3), the current study pits the mere effort motivational account of stereotype threat against a working memory interference account. In Experiment 1, females were primed with a negative self- or group stereotype pertaining to their visuospatial ability and completed an anti-saccade eye-tracking task. In Experiment 2 they were primed with a negative or positive group stereotype and completed an anti-saccade and mental arithmetic task. Findings indicate that stereotype threat did not significantly impair women's inhibitory control (Experiments 1 and 2) or mathematical performance (Experiment 2), with Bayesian analyses providing support for the null hypothesis. These findings are discussed in relation to potential moderating factors of stereotype threat, such as task difficulty and stereotype endorsement, as well as the possibility that effect sizes reported in the stereotype threat literature are inflated due to publication bias.", "pred_label": "__label__POS", "pred_score_pos": 0.7202973365783691}
{"content": "Can you eat it?\nThe plant has traditionally been eaten, which shows it is safe for human consumption in reasonable quantities.\nTo begin with, not all parts of the plant are edible (as with rhubarb) and they are only edible at a certain time of the year. The shoots in the spring are tender enough to eat, but they have to be gathered before the stems become hard and woody. The ideal time to eat knotweed is mid-April to May. However, if you are harvesting it you must ensure that you cause no spread of the plant, as this is illegal within the UK. We recommend that no root material is taken, just the tops of the shoots.\nHowever, the resveratrol contained in it is damaged by heat, so the best way of getting the resveratrol is either by eating a small part of the shoots or making a tincture.\nResveratrol is not readily water soluble. However, this plant tastes a bit like rhubarb, which is not the most pleasant! Also, the emodin within the plant has effects on gastrointestinal ailments, due to laxative effects, so accurate dosing is needed to ensure that these effects are not problematic.\nJapanese Knotweed Root may interact with several medications, such as blood thinners and drugs metabolized by the P-450 enzyme system in the liver. Consult your healthcare provider before adding to your regiment of drug treatment.", "pred_label": "__label__POS", "pred_score_pos": 0.9514297246932983}
{"content": "Maybe you are familiar with the events that unfolded at the base of Mount Sinai in Exodus 32 when the Israelites worshipped a golden calf, and the original Tablets of the Testimony were shattered. As you reflect on that story, put yourself in it, and consider with which of the following three groups you would have been aligned.\nWe’ll call the first group, the idolators. This group asked Aaron to make them an idol because they interpreted Moses’ absence as God’s abandonment of them. Aaron agreed and utilized their gold jewelry to craft an idol shaped like a calf. The people then proclaimed, “These are your gods, O Israel, who brought you out of the land of Egypt” and scheduled a religious festival for the next day in which they engaged in idolatrous worship, raucous behavior, and sexual promiscuity (Exodus 32:4-5). The text initially implies that the entire nation of Israel participated in this idolatrous activity. However, only 3000 people were punished for this sin (Exodus 32:28). At this time, the Israelites consisted of more than 600,000 men, not including women and children (Numbers 1:45-46). Therefore, it would seem that the vast majority of them did not commit idolatry that day. So, the first group we encounter at the base of Mount Sinai actively participated in the worship of the golden calf. This group chose to fulfill their personal desires rather than adhere to the will of the Lord. They had come to the point that they wanted to do what felt right instead of what was right.\nThe second group was comprised of Levites. When Moses arrived on the scene, his “anger burned hot” (Exodus 32:19). As a result, he shattered the Tablets of the Testimony, destroyed the idol, then stood in the entrance of the camp and drew a line in the sand. It was there that Moses made the Israelites choose between the one true God and the idol they had just created by saying, “Who is on the Lord’s side? Come to me” (Exodus 32:26). Upon hearing this challenge, only the tribe of Levi choose the Lord’s side. The other eleven tribes refused to move. Sadly, this means that a vast minority chose to align themselves with God. So, the second group we encounter at the base of Mount Sinai are those who willingly choose to be on God’s side. This is the group that was given the assignment of executing those who participated in the worship of the golden calf (Exodus 32:27), and, despite the difficulty of that assignment, they faithfully obeyed it because they understood that when you choose God, you choose to do whatever He commands.\nThe final group at the base of Mount Sinai could be called the fence riders. This group is not as easy to spot as the idolators and the Levites, but they are definitely present. If only 3000 people were executed for worshipping the golden calf and only one tribe chose to be on the Lord’s side, then what were the rest of the Israelites doing? I believe they were riding the fence. They weren’t explicitly opposing God by worshipping an idol, but they also weren’t willfully choosing God either because they didn’t join Moses when he said, “Who is on the Lord’s side?” Instead, this group remained noncommittal. Indecision was their decision. And as a result, they may not have been guilty of idolatry, but they were still guilty of rejecting God.\nNow, with which group would you have been identified? Would you have been numbered with the idolaters? Would you have searched out for your own god to appease your interests? Would you have chosen what felt right instead of what was right? Or would you have been numbered with the Levites? Would you have chosen the Lord’s side even though you would have been in the minority? Would you have been obedient to God even though such obedience would have required you to complete a difficult task? Or would you have been numbered with the fence riders? Would you have remained silent when faced with the decision to choose sides? Would you have been guilty of tolerating sin rather than opposing it? Would you have chosen to stand still?\nMoses drew a line in the sand, and that line still exists today. We must choose whether we will serve idols, remain noncommittal, or serve the one true God. Only one of these three options leads to the Promised Land. May each of us choose to boldly proclaim the same words that Joshua used—”as for me and my house, we will serve the LORD.”", "pred_label": "__label__POS", "pred_score_pos": 0.8321306109428406}
{"content": "Hurricane Season with a Chance of Fraud How to Prepare for Major Disasters.\nStart out by reviewing your credit report and the ability fraudsters have to access your credit information. You wouldn't leave your home unlocked during time away! Consider contacting an agency to secure and lock your credit.\nThis is one of the easiest ways to safeguard yourself from identity theft. However, your concern should not just be limited to fraudsters opening new accounts in your name when they steal your identity. You can also protect your credit reputation from insider attacks. (For more information on how this can happen, read about Confessions of an ID Theft Kingpin Part 1 & 2.)\nWhen freezing credit you stop your personal identifiable information, like financial habits, from being revealed. By activating a freeze with all three major bureaus you prevent fraudsters from using any of your compromised personal identifiable information to apply for credit cards or other loans. Fraudsters may intend to reissue items with changes that benefit them or even apply for a job. (Note - you also prevent companies from researching you for legitimate reasons like your own job applications.) While this creates additional steps for these application processes, it protects your personal identifiable information around the clock and helps reduce the value of any breached information.\nWhen lifting a credit freeze, or temporary removal of a credit freeze, you make maintaining a lock a nonevent. In the past, this could cost a significant amount of money and complexity to maintain. Now, there are no longer any costs to freeze or unfreeze your credit report. This is thanks to the enactment of the Economic Growth, Regulatory Relief and Consumer Protection Act. While there are many third-party companies providing similar services, you should always start with the credit bureaus.\nCredit Reporting Agency Contact Information: Additional areas to stay vigilant when disasters strike. Identify clean-up and repair emails and calls. Unlicensed contractors and scammers may quickly appear with promises to make repairs. Many times an upfront payment is requested with no intent to complete the work. Imposter scams come in many varieties. They will likely try to gain your trust quickly so that you will send payment. Be aware of potential rental listing scams if displaced from your home. Disaster-related charity scams often try to make a quick profit from the misfortune of others. Check with the FTC’s Charity Scams information and review the organization with the Better Business Bureau (BBB) for additional information. Excellent safety practices for periodic review. Review your credit report annually, and without an impact to your score, with one free informational report. Monitor your active accounts for fraudulent activity such as new loans or charge accounts. Review current threats to consumers using the Federal Trade Commission (FTC) site. Be aware of breaking news stories such as data breaches or natural disasters. Secure and safeguard your essential documents and login information.\nAuthor:\nBob Bender\nFounders CTO\nIf you have questions about this article or other cybersecurity issues, please email CTOCorner@foundersfcu.com.", "pred_label": "__label__POS", "pred_score_pos": 0.543351948261261}
{"content": "Features & Columns Advice Goddess: Does This Cheapen Our Entire Relationship? My ex just started dating a female friend of his. When we were together, I always worried about the chemistry I felt they had, and it hurts that they got together right after our breakup. Does this mean he's always had feelings for her? Does it cheapen our entire relationship? Bummed\n\"I only have eyes for you\" is sometimes actually true, like when two people in a relationship are being held hostage together in the trunk of a car.\nBeyond small-space kidnappings, the reality is typically more like: \"I only have eyes for you. And you. And you. And, hey, is that your sister?\" We're each attracted to a whole crop of people. However, attraction doesn't necessarily lead to action, at least for those of us who have a psychological moat holding us back. It's largely two things that keep us from sneaking out and having sex with the hot neighbor: love for the person we're with and a personality trait called conscientiousness.\nConscientiousness, which has a bunch of letters in common with \"conscience,\" is defined by social and personality psychologist Brent Roberts and his colleagues as \"the propensity to follow socially prescribed norms for impulse control, to be goal directed, to plan and to be able to delay gratification.\"\nA person with a solid helping of conscientiousness cares about the impact of their behavior on other people. However, being attracted to somebody happens automatically. So, conscientiousness does not prevent a wandering eye, just wandering sex parts that get busy in its wake.\nEven people high in conscientiousness probably have a mental file drawer of potential partners\"backup mates\"even when they have a partner they love. Research on backup mates by evolutionary psychologists Joshua Duntley and David Buss suggests we evolved to have these in mind, at least subconsciously, to shorten the reproductively costly breaks between being dumped or having a partner die on us and landing their replacement.\nUltimately, you have no control over another person's feelings. What you can control are your choices, using love and conscientiousness as a guideline for whether to stay or move on. Regarding conscientiousness: A man whose actions day to day suggest he's ethical is a man who's less likely to end up in bed with somebody else while he's still in a relationship with you. As for love and attraction, a man who seems to have serious hots for you, sexually and as a person, is more likely to stick around and keep loving you. You'll still probably catch him glancing at sparkly ladies at parties, but try to keep in mind that window-shopping is not the same thing as robbing the store.\nMy boyfriend and I broke up two years ago, and I guess I'm not over him. I'm not still pining for my ex, but I find myself comparing every guy I date to him. How do I get him out of my head? Haunted\nWhen you're looking for love, it's good to avoid wearing distracting jewelry, like an ex-boyfriend-shaped anvil on a chain around your neck.\nBut maybe you don't have the problem you think you do: not being over your ex. After all, you say you aren't pining over the guy. Consider that we don't make judgments by pulling them out of thin air. We need comparisonsto things, people or pricesas a starting point. An example of this comes from economic psychology. Psychologists Daniel Kahneman and Amos Tversky observed that the price a person is initially exposed to serves as an \"anchor,\" influencing decisions they subsequently make. For example, Kahneman writes that upon mention of a charitable contribution of $5, research participants were willing to contribute $20, on average. \"When the anchor was a rather extravagant $400, the willingness to pay rose to an average of $143.\"\nHowever, when we have no reference point, no starting point for comparison, judgments we make tend to be all over the place, not refined or useful. For example, \"Is ice cream good?\" versus the comparison, \"Is ice cream better than gluten-free kale cookies sweetened with artisanal tree rot?\"\nChances are you're using your ex as a reference point to recognize the qualities you do and don't want in men you encounter. Consider divorcing these qualities from the man by listing them, perhaps in a note on your phone you can periodically reflect on. It might not entirely remove him from your mind, but it could make you feel less haunted by him, less like you aren't over him. Remember, \"Objects in the rearview mirror ...\" um, look much closer when you rope them to your mental hood like a deer.", "pred_label": "__label__POS", "pred_score_pos": 0.7637314796447754}
{"content": "Complete ownership and control Save on costs in the long-term Access to advanced features\nTelephone systems using VoIP and SIP trunks are advantageous as they provide the ability for software updates and improved features to be rapidly deployed by your provider, without the need to access your premises. A business will no longer have to request upgrades and wait for an engineer to visit.\nAdvanced features\nOnce you are connected via SIP Trunking, a range of productive features can be accessed using VoIP phone systems. These include user statuses, call logging, call queuing, call forwarding, conference calls, auto time updates, mobile apps, voicemail to email, calling name retrieval, call recording, priority alerts, auto attendant and more.\nFor larger, multi-site businesses, the flexibility to access and control these applications across the internet is essential and different users, sometimes with different on-premise equipment, can tailor requirements to specific needs.\nIn the long term, using a SIP trunking on premise telephone system can save money when compared to a hosted telephony solution, however, the upfront costs can be considerably higher.", "pred_label": "__label__POS", "pred_score_pos": 0.5318472981452942}
{"content": "A layoff is a challenging experience, regardless of whether you saw it coming. It means being unemployed, usually through no fault of your own, and often leads professionals to worry about their careers.\nWhile being laid off is traumatic, to a degree, it can also be the start of something amazing. By maximizing your time, you can turn a negative situation into a positive one. If you want to make the most of your new circumstances, here are some tips that can help.\nFeel Your Feelings, But Move On\nThe moment you’re notified of a layoff, it’s normal to feel a range of emotions. If you enjoyed your job, you might feel sad. If you weren’t the biggest fan of your position, you might feel some relief, mixed with a dose of worry. In either of those situations, you might experience a bit of panic about your career or financial stability.\nNo matter what emotions go coursing through you, it’s fine to spend a moment feeling them. Acknowledge the hurt, anger, relief, excitement, or anything else that comes with the situation. Then, once you’ve had a chance to experience that, prepare to move on.\nDwelling on your layoff won’t help you keep on track. While it may not be easy, letting those feelings go is a critical step. That way, you can refocus on what’s going to come next, allowing you to keep your career on target.\nReflect a Bit\nWhile you might think you need to start looking for new opportunities immediately, you may want to pause for a second before you do. Once you’ve acknowledged and moved on from your initial emotional response to the layoff, take a moment to reflect on your career.\nGetting laid off creates a natural opening for change. If your current path doesn’t feel right for any reason, you have a chance to steer it in a new direction.\nConsider which skills you did and didn’t enjoy using in your last job. Figure out if your previous industry was a good fit. Research other positions that you may be suited for, using your transferable skills as a guide to identify options.\nYour goal should be to determine if a new path is what you need or if you still believe that your current one is a good match. That way, when you do launch a job search, you can take it in the right direction from the beginning.\nExplore Your Passions\nMost professionals fall into a bit of a routine. With a layoff, that pattern is disrupted. While this may seem like a bad thing, it can also be an opportunity. It gives you time to explore your passions, reigniting your interest in your current field, or giving you a chance to try out something different.\nIf you’ve been laid off, find opportunities to get involved in activities that inspire you. Try volunteering for an organization that matters to you, allowing you to keep your skills up and serve in a meaningful position while you plan your next step as a professional. Take a class in an area that interests you to boost your resume and keep yourself sharp.\nYour goal should be to find ways to feel positive about the future holds and to rejuvenate yourself professionally. That way, as you launch a job search, you can keep your energy levels high.\nUltimately, a layoff is a challenge that many professionals contend with at some point. By using the tips above, you can maximize your time, ensuring your career can keep moving forward. If you’d like to learn more, the team at The Advance Group can help. Contact us today.", "pred_label": "__label__POS", "pred_score_pos": 0.8284083008766174}
{"content": "The answer, as I've argued before, is to scrap the under-the-influence model altogether. Stop focusing on\nwhypeople drive poorly and start punishing them for driving poorly. A family of four killed when an oncoming car hops the median is no less dead if the driver was a mom distracted by her kids in the back seat, a drunk driver, or a teenager who lost control while sending a text message.\nIf you want to crack down on highway deaths, pass more severe penalties for reckless driving, regardless of the cause. You could gradually at more punishment for someone who causes an accident, causes injury, or causes a fatality. But the actual breaking of traffic laws should be the crime. When you focus on the cause of impairment, you get problems like Fourth Amendment-stretching sobriety checkpoints, or cops authorized to draw blood along the side of the road. Cell phone and texting bans become another excuse for cops to make pretext stops while drug profiling.", "pred_label": "__label__POS", "pred_score_pos": 0.6634966135025024}
{"content": "Reflective Journaling: Innovative Dialogue in LIS Education\nBURNS, Elizabeth Ann (2019)\nReflective Journaling: Innovative Dialogue in LIS Education. Paper presented at: IFLA WLIC 2019 - Athens, Greece - Libraries: dialogue for change in Session 234 - Education and Training. Abstract Reflective Journaling: Innovative Dialogue in LIS EducationInnovative pedagogy, embedded in LIS courses structures, is desired and strengthens LIS preparation. Including reflection as one such strategy can assist in building the reflective practice LIS educators hope students maintain in the field. While widely used in teacher preparation courses (Hodgins, 2014) reflective journaling equally aligns with the text-based nature of LIS coursework, especially as more LIS schools move to online formats (Kymes & Ray, 2012). This phenomenological case study explores structured, dialogic journaling as a pedagogical tool to inform the reflective practice of preservice librarians. Journals were introduced as a teaching tool in an early LIS course and structured using Schon’s (1987) Reflective Practitioner model. Additional points of data collection included journals from a faculty-guided teaching experience and a final journal entry collected after one year of practice. Findings explore participant perception on reflection through incorporated use of reflective journals to explore reflection in action, reflection on action, and reflection on reflection in action as a structured exercise. Implications suggest journaling as a teaching tool in LIS programs might promote more reflective practitioners and practitioners who are better able to critically reflect on practice when provided the experience in coursework.\nItem Type: Conference or Workshop Item (Paper) Conference details: IFLA WLIC 2019 - Athens, Greece - Libraries: dialogue for change Session 234 - Related URLs: Divisions: Division 4 Support of the Profession > Education and Training Section Authors:\nUncontrolled Keywords: Reflection, LIS Education, Journals, Pedagogy, Reflective Practitioner Date Deposited: 25 Jul 2019 11:08 Last Modified: 25 Jul 2019 11:08 URI: http://library.ifla.org/id/eprint/2531 FOR IFLA HQ (login required)\nEdit item", "pred_label": "__label__POS", "pred_score_pos": 0.5160915851593018}
{"content": "Philanthropy’s potential role in the science and development of nuclear power is significantly constrained, both by the overlap with impact investors and the traditionally dominant role played by government, especially abroad. Yet, the urgency of the need to address climate with technical solutions demands more of those with the ability to donate.\nSee\nInside Philanthropy: “Philanthropy’s Critical Nuclear Moment.”", "pred_label": "__label__POS", "pred_score_pos": 0.6940537691116333}
{"content": "Collaborative live events blend real-time engagement with broadcast video reach\nAs people and communities around the world continue to adapt to remote work and distance learning, amid evolving public health requirements, businesses, nonprofits, and public officials are working to find ways to better engage with stakeholders. Many organizations are turning to online communications to connect with customers, employees, constituents, and others. However, building a stable, secure, scalable online communications infrastructure can present a variety of challenges, particularly for organizations who want not only to broadcast to audiences, but wish to enable two-way communications between speakers and participants.\nOrganizations need to stay focused on delivering content of value that keeps stakeholders, supporters, or constituents engaged; and high-quality, highly reliable streaming video is key to that mission. These live video workflows need to incorporate technologies that avoid delay in communication between participants, yet preserve the ability to reach audiences on a global scale. Reliability remains essential so that critical, time-sensitive updates are available in real time to anyone who wants to see and hear them. Security, too, is of the utmost importance, ensuring information can be presented without disruptions or vulnerabilities. And, these workflows must support a dependable, user-friendly way for individuals to engage with speakers from the safety of their homes or other locations.\nTraditionally, one-way communication, such as television broadcasting uses a one-to-many approach. AWS Media Services support this style of communication by making it fast and easy to produce, process, and deliver broadcast-grade video using over-the-top (OTT) streaming technologies. Two-way communications, such as video conferencing, are another set of technologies that enable real-time multi-user collaboration. Amazon Chime is an example of such a service, providing a collaborative, video-based online environment where people can meet and share information.\nHistorically, these services have catered to different types of video workflows, while offering specific functionalities that help audiences stay engaged. Now, with a new collaborative live event solution powered by the Amazon Chime SDK, customers can bring together enterprise-class collaboration with broadcast-grade streaming, in a single interactive workflow. This collaborative live event solution provides audiences an adaptive web landing page and integrated video player for watching a live streaming event. Participant controls are exposed within the streamlined web interface, allowing audience members to raise a virtual hand or ask a question about the broadcast feed. Participants can even transition from a passive viewership role to active participant role via a moderator-assisted transfer.\nUsers can now access and deploy the collaborative live event solution using pre-built AWS CloudFormation templates from the resource links listed at the end of this post. Reference the following steps to get started with your collaborative live event:\nDeploying a collaborative live event Deploy a collaborative live event using the provided CloudFormation Templates; Verify the Amazon Chime SDK Lobby Room, Moderator Room, and Talent Rooms are ready; Verify AWS Media Services and Amazon CloudFront establishes the broadcast pipeline; Attach the Amazon CloudFront endpoint to the Amazon Chime SDK Lobby Room; Schedule a meeting, invite participants, and socialize the event to audiences anywhere. Watch or join a collaborative live event Direct all participants to your Lobby page where they can watch the live broadcast; Participants watching the broadcast can raise a virtual hand to ask a question; A moderator can engage with any participant in a private one-on-one video session; A moderator can choose to promote a participant into the Talent Room, while maintaining control over the participant’s camera and microphone settings; The promoted participant can now engage in a real-time video discussion with those in the On-Air Talent Room, becoming an active part of the broadcast event.\nFinally, the collaborative live event solution can be deployed using simple webcam components or augmented with broadcast-grade equipment and services to achieve the level of quality your live event requires. Here are a few example architectures to consider:\nAWS and its Amazon Partner Network companies offer a range of solutions to help customers meet their objectives for one-to-many communication as well as one-to-one engagement, from pre-built architectures to custom solutions designed to unique specifications. A recent blog post documents an AWS solution used by the state of Ohio to deliver daily briefings from the governor’s office. Other use cases for this technology include virtual press briefings, legislative hearings, virtual classrooms, remote corporate all-hands meetings, shareholder meetings, virtual town hall meetings by elected officials or candidates running for office, and many more.\nCustomers from the private and public sectors are leveraging innovative cloud-based solutions to remain engaged with their audiences while adapting to new virtual workplace environments. Many customers have expressed the need for a collaborative live event solution such as this. Now, with a new collaborative live event solution powered by the Amazon Chime SDK, manufacturing organizations with geographically dispersed teams can facilitate collaboration without worrying about setting up infrastructures; political candidates running for office can engage with supporters without worrying about downtime or disruption; and, live event producers can set up new experiences for participants using AWS cloud-native solutions without having to rely on inflexible, bespoke hardware.", "pred_label": "__label__POS", "pred_score_pos": 0.9576832056045532}
{"content": "Plastic pollution is a global phenomenon with significant impacts on the marine and coastal environment. The physical properties and uncertainties associated with marine plastic, combined with the transboundary nature of the problem and a lack of international markets for control (such as a cap and trade scheme) has led to a lack of effective global actions to address the challenge of marine plastic. This lack of coordination and effective control persists despite increasing worldwide recognition of the problem. Recognizing this critical and unresolved problem, the fundamental aim of the proposed research is to bring new insights to bear on the economic damages associated with marine plastic, the costs of reducing this pollution problem, the net benefits of international coordination over reductions in marine plastic, and the conditions under which mutually beneficial coordination can occur.", "pred_label": "__label__POS", "pred_score_pos": 0.9994708299636841}
{"content": "Background: Despite the promising findings from short-term intervention trials, the long-term effect of habitual fruit and vegetable intake on blood pressure (BP) remains uncertain. We therefore assessed the prospective association between baseline intake of fruits and vegetables and the risk of hypertension in a large cohort of middle-aged and older women. Methods: We conducted analyses among 28,082 US female health professionals aged ≥39 years, free of cardiovascular disease, cancer, and hypertension at baseline. Baseline intake of fruits and vegetables was assessed using semiquantitative food frequency questionnaires (FFQs). Incident hypertension was identified from annual follow-up questionnaires. Results: During 12.9 years of follow-up, 13,633 women developed incident hypertension. After basic adjustment including age, race, and total energy intake, the hazard ratio (HR) and 95% confidence interval (CI) of hypertension was 0.97 (0.89-1.05), 0.93 (0.85-1.01), 0.89 (0.82-0.97), and 0.86 (0.78-0.94) comparing women who consumed 2- <4, 4- <6, 6- <8, and ≥8 servings/day of total fruits and vegetables with those consuming <2 servings/day. These associations did not change after additionally adjusting for lifestyle factors but were attenuated after further adjustment for other dietary factors. When fruits and vegetables were analyzed separately, higher intake of all fruits but not all vegetables remained significantly associated with reduced risk of hypertension after adjustment for lifestyle and dietary factors. Adding body mass index (BMI) to the models eliminated all associations. Conclusions: Higher intake of fruits and vegetables, as part of a healthy dietary pattern, may only contribute a modest beneficial effect to hypertension prevention, possibly through improvement in body weight regulation.", "pred_label": "__label__POS", "pred_score_pos": 0.9772190451622009}
{"content": "Abstract\nLong-chain acyl-CoA dehydrogenase (LCAD) deficiency is a disorder of mitochondrial fatty acid oxidation that is characterized by hypoglycemia, muscle weakness, and hepatoand cardiomegaly. To characterize variant LCAD, we first carried out preliminary experiments using pure enzyme preparations. Despite the significant sequence similarity of LCAD to medium-chain acyl-CoA dehydrogenase, the antibody raised against rat LCAD was monospecific for human and rat LCAD and did not cross-react with either human or rat medium-chain acyl-CoA dehydrogenase. Immunoblot analysis of variant LCAD in cultured fibroblasts from nine patients with LCAD deficiency revealed a single LCAD band in all nine LCAD-deficient cell lines. Each variant LCAD was comparable in molecular size and quantity to normal LCAD, suggesting that the LCAD mutation in each of these cell lines is likely to be a point mutation that produces a stable variant LCAD. The uniform nature of variant LCAD suggests that only a single, or at most a few, prevalent point mutations may be found in the majority of LCAD-deficient patients. If this is the case, it should be possible to devise a molecular diagnostic method for LCAD deficiency.\nASJC Scopus subject areas Pediatrics, Perinatology, and Child Health", "pred_label": "__label__POS", "pred_score_pos": 0.7176804542541504}
{"content": "This report is on the impact of poor sanitation on the safety, well-being, and educational prospects of women. Girls’ lack of access to a clean, safe toilet, especially during menstruation, perpetuates risk, shame, and fear. This has long-term impacts on women’s health, education, livelihoods, and safety but it also impacts the economy, as failing to provide for the sanitation needs of women ultimately risks excluding half of the potential workforce.WATERAID ; UNILEVER DOMESTOS ; WSSCC (2013): We Can't Wait. A Report on Sanitation and Hygiene for Women and Girls. London / Geneva: WaterAid, Unilever Domestos, Water Supply & Sanitation Collaborative Council (WSSCC) URL [Accessed: 11.01.2014]", "pred_label": "__label__POS", "pred_score_pos": 0.7377886772155762}
{"content": "The Constitutional Court ruling on Tuesday, 29 August 2017, favours all property owners! The ruling stated that municipalities cannot hold a new property owner liable for a previous owner’s historical municipal debt.\nWhat does this ruling mean for Business and Property Owners? The precedent-setting ruling will provide relief to owners, who have been struggling with this burden for years and have been denied municipal services until the debt had been paid. According to Justice Edwin Cameron, “…the court found that upon transfer of a property, a new owner is not liable for old municipal deb.” The historical debt includes water, electricity, rates, and taxes charges associated with a property.\nWhen a property is sold, municipalities would be the first to claim the debt from the proceeds of a property sale. But if the previous owner still owed the municipality debt spanning over 2 years, the property was not allowed to be transferred to the new owner, according to section 118 (1) of the Municipal Systems Act. Judge Dawie Fourie declared Section 118 (1) and (3) of the Municipal Systems Act unconstitutional, as these sections “…unjustifiably limited the property rights of new owners under the Constitution.” Arguments against Section 118 included that making a new owner liable for historical debt could promote the deprivation of property, in line with the prescripts of the Bill of Rights.\nWhat does this mean for the Municipalities? According to the ruling by the Constitutional Court, municipalities may not attach and sell the property to settle the debt of the previous owner. Furthermore, municipalities may not refuse to supply municipal services because of outstanding historical debts. Property owners can now breathe a sigh of relief knowing that they will not be charged with others debt!", "pred_label": "__label__POS", "pred_score_pos": 0.8718653917312622}
{"content": "October 05, 2020\nMembers of The University of Kansas Cancer Center are busy preparing their application for National Cancer Institute (NCI) designation renewal, a prestigious distinction held by only 70 other cancer centers in the U.S. With this application, the team aspires to receive “Comprehensive” designation - the NCI’s premier ranking awarded to the very best cancer centers.\nTo retain designation, the cancer center undergoes a rigorous evaluation process conducted by nationally recognized peer reviewers every five years. The groundwork for application includes constant monitoring and documentation of the cancer center’s accomplishments, including research programs efforts, community outreach and engagement endeavors, as well as clinical trial growth and accrual. The application submitted in 2017 exceeded 1,200 pages.\nWhat is NCI Comprehensive designation? It is the gold standard, awarded to cancer centers that are recognized for their trailblazing research and leadership in developing leading-edge treatments. To attain this elite distinction, the cancer center must demonstrate significant depth and breadth in basic, clinical and translational research, with a clear focus on the cancers most affecting our communities. This requires a deep understanding of the cancer issues faced by those we serve and responding with tailored solutions. To move from NCI Designation to NCI Comprehensive, we must: Demonstrate solid basic research discoveries that build on our collective knowledge of cancer’s biology and apply these findings to advance new therapies. Identify cancer risk factors and develop actionable cancer prevention strategies. Create more clinical trial opportunities for patients, including underserved populations. Establish a strong, robust program for training a diverse oncology workforce ready to meet the needs of our catchment area and the nation.", "pred_label": "__label__POS", "pred_score_pos": 0.9405400156974792}
{"content": "In a survey conducted by BridgeLabz, it was found that 42% of freshers find live sessions with mentors best for on-the-spot query resolution, while 21% find offline classroom-based training to be a viable learning option, collaboratively making 63% of engineers opting for live sessions as a preferred choice.\nLearning\nAmidst constant disruption, professionals need to constantly improve their skills to distinguish themselves and provide maximum value in a hyper-competitive job market. By opening to the public parts of its continuous learning platform, Genome, the firm aims to help participants learn and master a wide variety of essential skills relevant to many key roles at the heart of digital transformation.\nResearchers reveal that they have successfully rebuilt the bridge between experimental neuroscience and advanced artificial intelligence learning algorithms.\nAs part of the programme, women candidates will have access to flexible work options including work from home, and flexible shift options depending on the role.\nThe entrepreneur says: Keeping eyes, ears and mind open to knowledge is the only way to get and stay ahead.", "pred_label": "__label__POS", "pred_score_pos": 0.5823420286178589}
{"content": "Objective reports from a credible chiropractic expert witness can help bolster your claims in court. You cannot have just any chiropractor serve as an expert witness, however. It is important to find someone with the right combination of experience and credentials to testify on the validity of your claims. Furthermore, you must seek someone without any conflicts of interest or scheduling issues. Start by exploring these key areas to find the most effective witness to serve as an expert on your case.\nAsk About Experience\nWhen you interview potential expert witnesses, inquire about their years in the chiropractic field and level of experience with key diagnoses and treatments. A solid working knowledge of anatomy and physiology is a must to speak on the conditions, terms and other facts required to prove your case. Explore each chiropractor’s underlying theories and approaches to find an expert who best aligns with your expectations.\nVerify All Credentials\nYour expert witness’s credibility depends on their credentials holding up to inspection. Make sure to do all your homework ahead of time to avoid compromising your case. You should verify your chiropractic expert witness’s degrees, certificates and other pertinent documents by checking with the issuing educational institution. Confirm the professional history information you recorded during the interview checks out before moving ahead in selecting your expert witness.\nCheck for Conflicts of Interest\nYour chiropractic expert witness must be free of all conflicts of interest to prevent the disqualification of their statements. If a conflict exists, it could impede confidentiality, causing the court to dismiss the witness as a viable party. To prevent that situation, verify that your preferred chiropractic witness has not ever served as an expert for the opposing party nor worked for them in any capacity.\nAssess Availability\nTo play an important role in your case, your expert chiropractic witness must actually show up on the scheduled court dates. Before hiring your expert witness, check availability across the entire expected hearing schedule. If you are having trouble choosing between two experts, allow schedule availability to be the tiebreaker to ensure your selected witness can take the stand as required for your case needs.\nFinding a Credible Chiropractic Expert Witness\nWhen you put in the legwork, it is possible to find a credible chiropractic expert witness for your case. If you would like assistance in finding your perfect candidate, contact our team at Expedient Medicological Services by calling 855-855-0525. We will help you find an expert with the ability to create comprehensive reports and provide clear, accurate testimony on the stand.", "pred_label": "__label__POS", "pred_score_pos": 0.6239341497421265}
{"content": "Developing a single blood test for the early detection of multiple deadly cancer types is a challenging endeavor for many reasons, including complex cancer biology.\nGRAIL is developing technology to attempt to overcome these challenges using the power of next-generation sequencing, machine learning, and data science. Through a robust and rigorous clinical study program, which includes our foundational study, the Circulating Cell-free Genome Atlas (CCGA) study, we are working to make a multi-cancer early detection blood test a reality.", "pred_label": "__label__POS", "pred_score_pos": 0.9785444736480713}
{"content": "Wellbeing in the Workplace At a time of such significant change in the sector it can be easy to overlook the need to nurture our greatest asset – our staff.\nThis Symposium will present the latest information on ways to assist in sustaining and nurturing a healthy and resilient workforce.\nWe will showcase strategies that support the mental, physical and emotional health of staff in the aged care sector, and demonstrate how a focus in this area can pay dividends across the organisation.\nIn an increasingly competitive environment, our staff truly are our most valuable asset, and it is important that we look after them and ourselves to ensure a workplace culture of health and wellbeing.\nCome and hear how other organisations have greatly improved their workplaces through implementing a range of innovative programs and hear about resources available to help you.\nThe symposium would be of interest to all health, aged care and community services managers and workers in the aged care sector.\nACS are offering a discounted\nrate for\nfive or more staff registered at the same time.\nWe look forward to seeing you at the Symposium", "pred_label": "__label__POS", "pred_score_pos": 0.6025628447532654}
{"content": "The metabolic syndrome among postmenopausal women in rural Canton: prevalence, associated factors, and the optimal obesity and atherogenic indices PloS One 2013, 8 (9): e74121\nOBJECTIVES: This research aimed to (i) determine the prevalence of metabolic syndrome (MetS) and its components; (ii) assess factors associated with MetS, and (iii) define optimal ethnic-specific cutoffs of obesity- and atherogenic-based markers to predict MetS among postmenopausal women in rural Canton.\nMETHODOLOGY/PRINCIPAL FINDINGS: The Rural Canton Diabetes and Metabolic Disorders Study, a population based cross-sectional study, was conducted during 2011-2012 in Canton. In person interviews, blood glucose and lipid measurements were completed for 4,706 postmenopausal women who did not receive hormone replacement therapy. MetS was diagnosed using criteria of the Joint-Interim-Statement (JIS), the International-Diabetes-Federation (IDF) and the Modified-Third-Adult-Treatment-Panel (M-ATPIII). Age-standardized prevalence of MetS was 38.4%, 28.8%, and 37.1% according to JIS, IDF, and M-ATPIII criteria, respectively. Excellent agreement was observed between three definitions (κ ≥ 0.79), in particular between JIS and ATPIII (κ = 0.98, 95%CI: 0.97-0.98). Factors positively associated with MetS were living in Southern Canton, personal income, current smoking, higher BMI, and family history of cardiovascular disease. However, regular leisure-time physical activity can have protective effects. The optimal cutoff values for waist-circumference (WC), waist-to-hip ratio (WHR), waist-to-height ratio(WHtR), BMI, HDL-cholesterol to total cholesterol ratio (HDL/TC), HDL-cholesterol to LDL-cholesterol ratio (HDL/LDL), and triglyceride to HDL-cholesterol ratio (TG/HDL) that predicted the presence of MetS were 79.5 cm, 0.86, 0.53, 22.47 kg/m(2), 0.33, 0.68, and 0.88, respectively.\nCONCLUSIONS: This study highlights the importance of MetS among postmenopausal women in rural Canton. Our findings contribute to help selecting Cantonese-specific markers to predict MetS and support the need to establish educational program for promoting healthy-lifestyles among this population.", "pred_label": "__label__POS", "pred_score_pos": 0.9773731231689453}
{"content": "Condominium and Cooperative Law in Kentucky\nCooperatives and condominiums are examples of \"common interest\" communities.\nThese are communities in which each resident rents or owns a residential unit. The residential units are part of a larger building, or complex of buildings, which are owned by another entity, such as a corporation or association. The residents are responsible for the upkeep of common areas, such as lawns and walkways. Rather than personally tending to these things, residents typically pay a fee that covers these necessities.\nSimply looking at the physical structure of a condominium or cooperative community, it would be nearly impossible to tell which is which.\nThis is due to the fact that there are no visual or physical characteristics that can distinguish one from the other. All the differences between them lie in the ownership arrangements that the residents have. With a condominium, the residents typically own their housing unit, and collectively own the land on which it sits. In a cooperative, the residents rent the units, and the land is owned by a single entity, either a corporation or other form of business association.\nLaws and Regulations Concerning Common Interest Communities in Hazard, Kentucky\nThere are a large number of laws in Hazard, Kentucky that can affect condominiums and cooperatives, but few, if any, of them are unique to such common-interest communities. Alternatively, they're mostly governed by laws of general application, covering zoning, contracts, and landlord/tenant relations.\nYour daily life in a cooperative or condominium community is more likely to be affected by the rules set by the owners or managers of the property, rather than the laws of your state or city.\nThe land that common interest communities occupy is typically private property. Therefore, the owners of the property are free to make certain rules governing what is and isn't allowed on it. A good manager or owner will typically make every effort to strike a balance between residents' freedom to do what they want in their homes, and the rights of their neighbors to a safe, clean, and reasonably quiet living space.\nSome rules set by property owners or managers may not be enforceable, however. For example, in Hazard, Kentucky, any rule which purports to exclude residents based on race, color, national origin, or religion will not be valid. There are likely some others, as well.\nCan a Hazard, Kentucky Attorney Help?\nIf you have a problem with your landlord, your community association, or a neighbor (which the landlord is unwilling or unable to address), an efficient real estate attorney in Hazard, Kentucky will be able to help.", "pred_label": "__label__POS", "pred_score_pos": 0.5735048055648804}
{"content": "A. D. Kelly, H. Kroeger, J. Yamazaki, R. Taby, F. Neumann, S. Yu, J. T. Lee, B. Patel, Y. Li, R. He, S. Liang, Y. Lu, M. Cesaroni, S. A. Pierce, S. M. Kornblau, C. E. Bueso-Ramos, F. Ravandi, H. M. Kantarjian, J. Jelinek, J-P J. Issa\nLEUKEMIA 31 10 2011 - 2019 2017年10月 [査読有り][通常論文]\nGenetic changes are infrequent in acute myeloid leukemia (AML) compared with other malignancies and often involve epigenetic regulators, suggesting that an altered epigenome may underlie AML biology and outcomes. In 96 AML cases including 65 pilot samples selected for cured/not-cured, we found higher CpG island (CGI) promoter methylation in cured patients. Expanded genome-wide digital restriction enzyme analysis of methylation data revealed a CGI methylator phenotype independent of IDH1/2 mutations we term AML-CGI methylator phenotype (CIMP) (A-CIMP+). A-CIMP was associated with longer overall survival (OS) in this data set (median OS, years: A-CIMP+ = not reached, CIMP- = 1.17; P = 0.08). For validation we used 194 samples from The Cancer Genome Atlas interrogated with Illumina 450k methylation arrays where we confirmed longer OS in A-CIMP (median OS, years: A-CIMP+ = 2.34, A-CIMP- = 1.00; P = 0.01). Hypermethylation in A-CIMP+ favored CGIs (OR: CGI/non-CGI = 5.21), and while A-CIMP+ was enriched in CEBPA (P = 0.002) and WT1 mutations (P = 0.02), 70% of cases lacked either mutation. Hypermethylated genes in A-CIMP+ function in pluripotency maintenance, and a gene expression signature of A-CIMP was associated with outcomes in multiple data sets. We conclude that CIMP in AML cannot be explained solely by gene mutations (for example, IDH1/2, TET2), and that curability in A-CIMP+ AML should be validated prospectively.", "pred_label": "__label__POS", "pred_score_pos": 0.8537729382514954}
{"content": "Abstract\nThe origin of granites was once a question solely for petrologists and geochemists. But in recent years a consensus has emerged that recognizes the essential role of deformation in the segregation, transport and emplacement of silica-rich melts in the continental crust. Accepted petrological models are being questioned, either because they require unrealistic rheological behaviours of rocks and magmas, or because they do not satisfactorily explain the available structural or geophysical data. Provided flow is continuous, mechanical considerations suggest that - far from being geologically sluggish - granite magmatism is a rapid, dynamic process operating at timescales of ≤100,000 years, irrespective of tectonic setting.", "pred_label": "__label__POS", "pred_score_pos": 0.874930739402771}
{"content": "Most athletes believe sleep is important for recovery, yet the importance of sleep for endurance athletes has remained unclear. This study examined nine endurance athletes under three experimental conditions: normal sleep, sleep restriction and sleep extension.\nEach condition required endurance cycling time-trials to be undertaken on four consecutive days, whereby nightly sleep was manipulated on intervening nights. Results showed that athletes better maintained endurance performance after three nights of sleep extension (8.5 hours per night). Compared with normal sleep (7 hours per night), an extra 90 minutes of sleep per night, over three consecutive nights, improved performance by an average of nearly two minutes (58.7 minutes vs. 56.8 minutes).\nThis study also found that endurance performance was impaired after just two nights of sleep restriction (5 hours per night). This study is the first to show the benefits of sleep extension for endurance performance and highlights the importance of cumulative sleep time for endurance athletes. Findings are particularly pertinent for endurance athletes required to compete over consecutive days, including cyclists during multi-day stage races. More broadly, other athletes competing over consecutive days (e.g., baseball players) or undertaking congested competition schedules may also benefit from sleep extension.\nView the abstract.", "pred_label": "__label__POS", "pred_score_pos": 0.9989800453186035}
{"content": "Special ASEAN-Australia Foreign Ministers’ Meeting on COVID-19\nToday, I joined ASEAN Foreign Ministers and the ASEAN Secretary-General to discuss Australia and Southeast Asia's cooperation to combat COVID-19 and to chart a course to economic recovery in the Indo-Pacific region.\nFor Australia, ASEAN centrality is the core of the Indo-Pacific, and we reiterated the importance of using the principles set out in the ASEAN Outlook on the Indo-Pacific to guide regional states' responses to COVID-19 and the post-crisis order.\nAustralia's health security and economic recovery are closely intertwined with those of our Southeast Asian partners. COVID-19 is a shared crisis – cooperation is essential if we are to avoid a prolonged global health crisis and economic stagnation. As ASEAN's longest-standing Dialogue Partner, we will stand together through this pandemic, just as we have in past crises.\nDuring today's Special ASEAN-Australia Foreign Ministers' Meeting on COVID-19, I emphasised Australia's concern that the pandemic is compounding strategic risks. It is placing strain on institutions, reducing resilience to shocks and creating the conditions for actions that undermine the rules and norms underpinning our shared stability and prosperity.\nMy counterparts and I reinforced our shared commitment to maintain an open, peaceful, stable and rules-based region, including by fighting disinformation, and our commitment to the principles set out in the ASEAN Outlook on the Indo-Pacific.\nIt is critical, in the current context, that we expand our cooperation on strategic challenges.\nDuring today's discussion, I made a $23 million commitment to help ASEAN bolster health security, economic recovery and stability in our region. In line with the Australian Government's new\nPartnerships for Recovery policy, this $23 million package includes: On health security, a new ASEAN-Australia health security initiative to help the region better prevent, detect and mitigate communicable diseases. On stability, a new ASEAN-Australia Political-Security Partnership, which will include a focus on risks to stability flowing from the pandemic; and enhanced support through the TRIANGLE in ASEAN program to vulnerable migrant worker communities. On economic recovery, an extension of our successful ASEAN-Australia Digital Trade Standards initiative to accelerate the region's digital transformation; and support to the ASEAN Post-Pandemic Recovery Plan to help drive a collective response.\nThis package complements Australia's wide-ranging Strategic Partnership with ASEAN, as well as the substantial bilateral work already underway with our Southeast Asian neighbours and our significant contributions to global efforts to fight COVID-19.\nMedia enquiries Minister's office: (02) 6277 7500 DFAT Media Liaison: (02) 6261 1555", "pred_label": "__label__POS", "pred_score_pos": 0.8576673865318298}
{"content": "When I was a young seminary student, I had to read an extensive commentary by a Dutch theologian. I had never studied Dutch writing before, and I really struggled to understand the syntax.\nI asked an older student for help, and he directed me to an annotated outline of another theologian who had dissected the work of my Dutch theologian. But when I picked up this outline, I discovered it was longer and more complex than the original work I was studying!\nKeeping It Simple\nDuring my years of academic study and pastoral ministry, I've found that it's natural for us to overcomplicate the stunningly simple faith to which we've been called. Is theology and doctrine important? Of course it is – I would never minimize its value – but I think we've interpreted the Christian life as more complex than the Bible describes.\nToday, I want to go back to the basics. I'm not suggesting that we do anything radical, like trash all our commentaries, but I just want to read Scripture verse by verse and see what it says about the way we're supposed to live.\nThe text that I love to go back to again and again is 1 Peter 2:11-12.\n\"Beloved, I urge you as sojourners and exiles to abstain from the passions of the flesh, which wage war against your soul. Keep your conduct among the Gentiles honorable, so that when they speak against you as evildoers, they may see your good deeds and glorify God on the day of visitation.\" (ESV)\nHow are Christians supposed to live? There are three key attributes to what I call \"The Christian Job Description.\"\n1. Exist As Aliens\n\"Beloved, I urge you as sojourners and exiles...\"\nA sojourner is one on a journey or pilgrimage, moving towards a final destination and temporarily pausing at a location. An exile is a person residing in a location that's not his or her original and desired homeland. That's me and you. This earth is not where we, as Christians, should call home. Eternity is our home. Forever is coming.\nBut here's the problem: you and I have grown too comfortable in our temporary home. We like the materialism and pleasure-orientation of Western culture. We measure success by the square footage of our house, the number of options on our luxury vehicle, the size of our retirement package, the quality of our cuisine and the letters after our name.\nIf we want to live like true, Biblical Christians, we'll live like aliens. That doesn't mean we'll be anti-social and live in monasteries, but we'll exist with a different set of values. We'll think long-term - 10,000 years into eternity long term. Our good days will be good days because the Kingdom of God is advancing, not because we're experiencing a little more temporary pleasure than yesterday.\nAre you living like an alien? Do you wake up every morning and long for Forever? Or have you grown too comfortable in this temporary sojourn?\n2. Fight As Soldiers\n\"Abstain from the passions of the flesh, which wage war against your soul...\"\nI don't know if you feel it or not, but there's a war of desire raging on the turf of your soul every day. Whether its in your marriage, with your kids, at your workplace, with your neighbor or during the privacy of your personal entertainment choices, there will be two desires competing for control of your heart, which in turn will affect your words and actions.\nIn the mundane moments of everyday interactions, the passions of the flesh (sin) will fight to control your heart. Simultaneously, the indwelling presence of the Spirit of God will be battling for the purity of your soul. These battles won't be won in dramatic Hollywood fashion with swords and shields, but by saying \"No!\" ten thousand times to your sinful desires.\nIf we want to live like true, Biblical Christians, we'll live like warriors. I don't mean aggressive and violent, trying to overthrow any external authority figure that doesn't believe the Bible. No, with humble and perseverant abstinence, we'll take seriously the sin that exists inside our hearts and not allow it to control of words and actions.\nAre you living like a soldier? Do you wake up every morning and get ready to do battle? Or have you grown too passive, surrendering to the passions of the flesh?\n3. Represent As Ambassadors\n\"Keep your conduct among the Gentiles honorable...\"\nThe job of an ambassador is to consistently and intentionally represent a leader who isn't physically present. In the same way, you and I are always \"on call\" - there's never a moment in life, whether its on vacation, at work, in your neighborhood, shopping at the store, working out at the gym, or whatever, where we aren't called to live with a ministry mentality and an ambassadorial attitude.\nWe are Gospel plumbers, Gospel teachers, Gospel lawyers, Gospel doctors, Gospel musicians, Gospel salesmen, Gospel moms and dads and Gospel neighbors. We're motivated by a single passion: that somehow and in some way, God would use our lives to accurately depict the truths of the Gospel and lead people to saving and liberating faith.\nIf we want to live like true, Biblical Christians, we'll live like ambassadors. We'll speak carefully with God-honoring words. We'll live admirably with Christ-honoring actions. We won't treat our lives as our own, but live instead for the King of Kings.\nAre you living like an ambassador? Do you wake up every morning and consider that your words and actions represent Christ? Or have you taken your life in your own hands, representing occasionally and on your own terms?\nNot Qualified\nLet me confess something to you. I don't always live with a destination mentality; I don't always live with a wartime mentality; I don't always live with an ambassadorial mentality. I indulge too much in the pleasures of this world and measure my success by earthly standards. I grow too comfortable with my sin and think it's not as destructive as it is. I don't step out in faith as often as I should and share the Gospel with those God has placed in front of me.\nIf I had to apply for the job of Christian, it wouldn't take Human Resources long to see that I'm not qualified! But being a Christian isn't about applying for the job; it's about receiving the gift of grace, living in obedience and following the example of Christ.\nIn every way, this passage points to Jesus. He was the ultimate exile; foxes have holes and birds have nests, but the Son of Man had nowhere to lay his head (Luke 9:58). He was the ultimate soldier, valiantly sacrificing his life to conquer sin and death (Colossians 2:15). He was the ultimate ambassador, coming down from heaven to do the will of the Father who sent him (John 6:38).\nWhat about you this week? Will you live like a true, Biblical Christian?", "pred_label": "__label__POS", "pred_score_pos": 0.819416880607605}
{"content": "Population-based data on trends and characteristics on polydrug overdoses are critically needed to help understand the changing drug epidemic in the United States, and to identify risk patterns and targets for overdose prevention for prescription and illicit opioid deaths. We conducted a statewide study in Tennessee to evaluate characteristics and trends of polydrug overdose deaths during 2013-2017.\nWe identified polydrug overdose deaths using ICD-10 codes and literal cause-of-death text in the death statistical files. We evaluated trends, contributing drugs, and demographic characteristics of overdoses (n = 2567 single-drug and n = 4683 polydrug deaths). Average annual percent change estimates (AAPCs) with associated 95% CIs were estimated using Poisson regression.\nPolydrug overdoses increased annually, with higher AAPC for polydrug compared with single-drug overdoses (AAPC: 13.6%, 95% CI: 10.6%-16.7% and 5.2%, 95% CI: 2.9%-7.5%, respectively). The highest increases in polydrug overdoses were observed in males (AAPC: 15.4%, non-Hispanic blacks (AAPC: 33.3%), and decedents aged 18-34 years (AAPC: 21.3%).\nAll drug and opioid polydrug deaths increased during 2013-2017, with the highest increases seen in males, blacks, and younger age groups. Over 80% of illicit opioid overdoses involved more than one drug, highlighting the need to go beyond opioids to prevent overdoses.", "pred_label": "__label__POS", "pred_score_pos": 0.617848813533783}
{"content": "According to a recent post, Gemini announced that they have secured an insurance coverage for the cryptocurrencies they store on their customers’ behalf in their online hot wallets. The digital currency exchange which facilitates buying, selling and storage of digital assets stated that the insurance would ensure extra security. The insurance coverage is available to the users of the exchange platform through a combination of third-party insurance underwriters.\nAfter meeting a series of top insurers in the industry, Gemini secured an insurance coverage for their digital asset platform in order to ensure greater security for their online hot wallets. The insurance would cover all the digital assets held by Gemini users in the exchange’s wallet.\nThey further stated that the new insurance coverage helped the platform take a step forward towards achieving their goal of “building the future of money”. Furthermore, the current Federal Deposit Insurance Corporation [FDIC]’s deposit insurance coverage which was used for fiat currencies will now be complemented by the new insurance coverage.\nIt was reported that insurance companies were always hesitant in covering cryptocurrency platforms due to the high risks associated with them. There have been several instances of hacking cryptocurrency platforms, resulting in a huge loss for both individuals and organization. The inefficient security standards, lack of internal controls and the regulatory problems with respect to the policies and procedures has resulted in insurers being skeptical about the cryptocurrency market.\nThis has led to several cryptocurrency exchanges and custodians to either not get insured or not acquire it due to high costing of premiums charged by the limited number of insurers.\nGemini’s Head of Risk, Yusuf Hussain further added that they were able to successfully gain the trust of its insurers. He added:\n“Gemini, a New York trust company, is indeed a safe and secure exchange and custodian where customers can buy, sell, and store digital assets in a regulated, secure, and compliant manner”\nThe Gemini exchange platform recently announced that they received regulatory approval to list Bitcoin Cash [BCH]. The exchange platform had also stated that they will list Litecoin [LTC] on 13th October.", "pred_label": "__label__POS", "pred_score_pos": 0.8641263842582703}
{"content": "National Making the Grade 2019 Making the Grade 2019 provides compelling evidence that K-12 public school funding continues to be deeply unfair in many states and a major factor contributing to disparities in education resources, opportunities and outcomes for the 50 million public school children across the United States. The report, which grades the states on three measures of fair school funding, was designed to assist policymakers, advocates and others as they answer a key question: How fair is public school funding in your state?\nELC’s previously published reports,\nIs School Funding Fair?: A National Report Card (Eds. 1-7) can be found on the Publications page.", "pred_label": "__label__POS", "pred_score_pos": 0.9969860911369324}
{"content": "The COVID-19 pandemic has required a rapid response by educators to meet student needs. CSI has transitioned to mostly distance learning for the present and the\nphysical library space is closed until further notice.\nMany instructors might find themselves looking for resources that are easily accessible and don't require an in-person visit to the library. Open Educational Resources (OER), are free and openly available instructional materials (including textbooks) that are born digital and available from anywhere with an internet connection.\nThis content is adapted from Open Oregon Educational Resources and is licensed under a Creative Commons Attribution 4.0 International License\nWebinars and Conferences CSI has implemented OER for selected sections in the Physics, Anthropology, Economics, Media Culture, Psychology, English, and Social Work, departments. For the 2019-20 academic year, students saved nearly $500,000 from using OER in place of traditional textbooks.\nIn 2019/20, CSI students in 7 departments saved nearly $500,000 in textbook costs with Open Educational Resources.", "pred_label": "__label__POS", "pred_score_pos": 0.512230396270752}
{"content": "Abstract\nOn-bottom pipelines for transporting oil and gas in deep water undergo significant changes in temperature and pressure during operating cycles, which cause a tendency for lateral buckling. Prediction and control of this phenomenon are required for the safe design and operation of these pipelines. However, the soil response under combined vertical and lateral loading is a significant area of uncertainty, and current practice relies on empirical expressions for the estimation of lateral pipe-soil resistance. This paper reports the results of finite element (FE) analyses of shallowly embedded pipelines under vertical and horizontal load. These analyses have been compared with collapse loads calculated using the upper-bound theorem of plasticity, and are used to construct yield envelopes defining the limiting combinations of vertical and horizontal load. The FE limiting loads were found to compare well with upper-bound plasticity solutions, and the internal soil displacements calculated in the FE analyses match the upper-bound and experimentally observed deformation patterns. The yield envelopes generated by the FE and upper-bound analyses have been fitted by simple solutions, which aid assessment of the ultimate resistance of shallowly embedded pipelines.", "pred_label": "__label__POS", "pred_score_pos": 0.8981592655181885}
{"content": "Aims: To test if The Transporters animation leads to improvement in emotion recognition in autistic preschoolers. Background: The Transporters aims to help autistic children to look at the human face and to learn about emotions. The series of 15 five-minute episodes features the adventures of 8 animated mechanical vehicles with human faces, each focusing on a different human emotion. Autistic children tend to avoid looking at human faces and find it hard to understand why facial features move in the way that they do. This inability to read emotions on the human face impairs their ability to communicate with other people. Autistic children are often fascinated by rotating wheels, spinning tops, rotating fans, and mechanical, lawful motion. They prefer predictable patterns. For this reason all the toy vehicles featured in the The Transporters run on tracks or on lines. The 15 key emotions portrayed in The Transporters aimed at 2 to 8-year-olds are: happy, sad, angry, afraid, excited, disgusted, surprised, tired, unfriendly, kind, sorry, proud, jealous, joking and ashamed. Each episode has an associated interactive quiz to help the child learn about the featured emotion. Method: In our clinical trial, autistic children watched the DVD for 15 minutes a day for one month, and were compared on the emotion recognition before the trial, and after. Results: We found that following a four-week period of watching the DVD, autistic children caught up with typically developing children of the same age in their performance on emotion recognition tasks. Importance: This demonstrates that aspects of empathy are teachable, and are engaging when designed to be autism-friendly. Relevance: For parents, teachers, clinicians and researchers. Funding: The Department of Culture, Media and Sport; the Autism Research Trust. Staff Members Selected Publications Systemizing empathy: Teaching adults with Asperger Syndrome and High Functioning Autism to recognize complex emotions using interactive multimedia., Development and Psychopathology 18:591-617 (2006), O. Golan, S. Baron-Cohen, S. Wheelwright and J. J. Hill", "pred_label": "__label__POS", "pred_score_pos": 0.807820200920105}
{"content": "Premarital counseling is the kind of counseling couples might engage in prior to getting married. This type of counseling can differ from couple to couple and therapist to therapist. Even the topics and intensity of premarital counseling can vary. For most people, premarital counseling involves conversations guided by a therapist with their soon-to-be spouse on topics that are important to cover before marriage. It can include topics like finances, expectations, family dynamics, sex, and children. There are curriculums created for engaged couples that are accessible to therapists to use in counseling. Some premarital therapy can be more intense for couples depending on the amount of conflict or issues they might be facing. For example, engaged couples who are volatile might have more intense discussions in therapy. A couple who has a history that includes infidelity might have deeper discussions about lack of trust in the relationship. In general, premarital counseling is going to look differently depending on the couple and therapist involved. However, it is a common practice many people participate in. Why do people engage in premarital counseling?\nConnect with a professional therapist online.\nItbrings up important topics to discuss. For somecouples, particularly young couples, premarital counseling can bring aboutcertain conversations that might they not have discussed before. Even ifcouples talk about particular issues like sex or finances, there might beaspects of the conversation they have not delved into before. Itcan bring to light any red flags within the relationship. There are some couples who probably should not pursue marriage.However, with the divorce rate hovering around 50%, people end up marrying eachother when maybe there were red flags they missed. While it is not going tonecessarily prevent all people from getting divorced in the future, premaritalcounseling can provide a place to catch red flags. A therapist can point outimportant issues for couples to consider before they get married. Itcan encourage conversations about expectations.Unmet expectations may seem small. However, they can be the root leading todeep issues that can destroy a marriage. Being open and honest aboutexpectations can be helpful as couples plan for their future. Premaritalcounseling can help couples understand each other’s expectations, adjustunrealistic expectations, and discuss how to manage expectations in the future. Itcan provide useful tools for marriage. Like mostcounseling, one of the purposes of premarital counseling is to provide valuabletools for couples as they prepare for marriage. It can help provide them with:the ability to communicate more effectively, tools for managing and handlingconflict, and strategies for maintaining a lifelong relationship. The hope isthat couples can utilize the tools learned in counseling throughout theirrelationship to keep it strong and healthy. Itcan prevent divorce. The hope is premaritalcounseling can prevent couples from getting divorced in the future. Whether isstops the relationship before the marriage begins or provides them with toolsfor maintaining the marriage, premarital counseling can help set up couples to besuccessful. It can give them what they need to potentially prevent thedissolving of a marriage. Itgets people more comfortable with the idea of counseling. Ideally, couples may not find they need counseling in the future.However, engaging in premarital counseling early in the relationship may allowindividuals to develop more of comfort level with therapy. The hope would bethat if a couple needed help in the future, they might be willing to step intocounseling because they have been there before.", "pred_label": "__label__POS", "pred_score_pos": 0.7414696216583252}
{"content": "On 30 March 2017, the European Economic and Social Committee (EESC) adopted an opinion on the European Commission's proposed directive on business insolvency, which is intended to harmonise preventive restructuring procedures across Europe. While fully supporting the Commission's shift from liquidation to early restructuring in dealing with business insolvency, the EESC proposes a set of measures to help prevent its social damages. MVU\nNothing can escape today's digital revolution. The \"internet of things\", 3D printing, artificial intelligence, big data, online platforms and the sharing economy are bringing new businesses into the digital arena and create new opportunities for innovative SMEs and start-ups. The digital revolution is bringing about changes in modes of production and patterns of consumption, how we understand the world, and even how we live together as a society.", "pred_label": "__label__POS", "pred_score_pos": 0.569359302520752}
{"content": "The IFN system is a major mechanism by which many viruses evade the cellular antiviral response. DENV and ZIKV can suppress Type I IFN signaling, but the exact mechanisms remain to be fully understood. Moreover, emerging literature indicates that the type I IFN system mediates antiviral immunity in a highly context-specific manner depending on the virus, cell type, and host species. Therefore, we have been using our mouse models to understand the mechanisms by which type I IFN contributes to antiviral immunity during DENV and ZIKV infection. We have previously determined that type I IFN production is regulated by two signaling pathways: the STAT1-dependent and the STAT1-independent pathways. We have defined the latter mechanism of protection against DENV infection to be the type I IFN receptor-STAT2 pathway, and revealed that the type I IFN receptor-STAT2 pathway, in the absence of STAT1, modulates type I IFN production and interferon-stimulated gene (ISG) response in a delayed manner. Studies are underway to define the particular interferon regulatory factor and ISG mechanisms through which both the STAT1-dependent and STAT2-independent pathways contribute to protection vs. pathogenesis using both mouse models and human cell culture models.", "pred_label": "__label__POS", "pred_score_pos": 0.8140774369239807}
{"content": "For construction companies and contractors, the hardest part of a job can, unfortunately, sometimes be collecting payment. When a customer refuses to pay or introduces another dispute, contractors often need to take legal action to ensure they are paid for completed work.\nA mechanics lien is a legal claim which can be placed upon a property to protect contractors, suppliers, and subcontractors. By placing a lien on a property, the contractor gains a security interest in the property, which can help the contractor receive payment in the event that a client does not pay according to the contract. This guide contains everything you need to know about a mechanics lien.\nWhat Exactly Is a Mechanics Lien?\nA mechanics lien is often placed by contractors, subcontractors, or suppliers who have completed work or provided supplies for a job but have not received payment. It is a means of protecting against unpaid invoices.\nIf you complete work—for example, construction on a home renovation—and the client doesn’t pay you, a mechanics lien is an effective means of seeking payment and ensuring the terms of your contract are respected. These liens can be applied to real estate and, less commonly, personal property such as vehicles or equipment.\nIf you choose to file a document in your county, the file will be attached to the property. This means that if payment isn’t made and the lien remains in place, there will be an unsettled debt on the property. If the house is put up for sale by the owners and a bid is accepted, the lien must be cleared before the owner receives payment for the property.\nWho Can File a Mechanics Lien?\nDirect contractors, subcontractors, laborers, suppliers, equipment lease companies, and any other professionals who are authorized to provide site work can file a mechanics lien if they are not paid for their work or supplies.\nIf a license is required to complete work, the individual must have the relevant license to proceed with the lien. A mechanics lien can be placed upon a property if the customer doesn’t pay their bill, but it’s also possible to file for a lien in cases where the client is not directly at fault. If a supplier has not been paid by a contractor for materials or equipment, for example, a lien can still be placed on the property.\nSimilarly, if the work is being paid for by an insurance company or another responsible party, a lien can still be placed on the property itself, and ultimately the property owner will be responsible for ensuring payment is completed.\nWhere to File\nIf you wish to file a mechanics lien, you must complete and submit documentation within the county where the project is located. Each county may have slightly different rules and regulations, so it’s critical to check with the recorder’s office before you proceed.\nIf you don’t follow the relevant guidelines, or if you get information like the dates or locations wrong, there could be significant delays and you could forfeit your rights to file a lien.\nWhen to File\nThere are strict requirements linked to the time frames and steps for filing a mechanics lien. If deadlines are not respected, you may lose your right to file. There are specific deadlines in place for each phase of the process of filing for a lien, but these can vary depending on the state where you file.\nCalifornia’s deadlines are as follows:\nPreliminary Notice: Subcontractors and suppliers must serve the property owner, and the direct contractor and lender, if relevant, a preliminary notice within 20 days of the first instance of providing labor or materials. Mechanics Lien: The deadline for filing a mechanics lien is 90 days from the completion of the project. This period changes to 30 days if a property owner or other applicable party files a notice of completion or cessation. Enforcement: After filing your lien, you have 90 days from the date of recording the claim to enforce it. It is possible to extend the deadline in cases where both the property owner and the claimant sign an Extension of Credit document. Enforcing a lien involves taking court action to foreclose on the property. But if the lien is satisfied, you must release or cancel the lien.\nFailing to comply with deadlines can result in unsuccessful attempts to file a mechanics lien, so it’s crucial for contractors and subcontractors to be aware of the specific dates and phases involved in the process.\nEnforcing a Lien\nBecause lien enforcement ultimately ends in foreclosure if it is successful, property owners usually want to avoid this action, and so lien enforcement is not often required; generally, the preliminary notice and placing the lien itself are enough to encourage the owner to pay.\nHowever, when it is required, you must file a lawsuit to enforce the lien, with all the drafting, filing, and serving that goes along with it. At this point in the lien process, you will most likely need a construction law attorney to assist with filing the suit.\nIf you have concerns about missed or delayed payments, or you have questions about filing a mechanics lien, a construction law attorney can help you navigate the process with minimal hassle. An experienced attorney will understand the ins and outs of filing a lien.\nAt The Mellor Law Firm, our expert construction law attorney can undertake the leg work for you to free up time to focus on other projects and eliminate stress. Contact us today if you need assistance with filing or enforcing a mechanics lien or solving another construction dispute.", "pred_label": "__label__POS", "pred_score_pos": 0.9069685935974121}
{"content": "While uncertainty is fanning the flames of fear, the flipside is that this is also an opportunity to manage our reactions, step into our strongest selves and help others do the same.\nThis is a super-challenging period, there is no doubt, but within that, what if we could also understand that we have two options: to drop into fear, or to take another perspective – one that helps us navigate these times, and come together to get through this global pandemic.\nWhat if we...\n50% Complete\nEnjoy this free video series to get you going with greater clarity and confidence. Gain access Now!\n*You'll also be the first to get the latest strategies to inspire your most fulfilling life.", "pred_label": "__label__POS", "pred_score_pos": 0.5886774063110352}
{"content": "Improving energy efficiency with less greenhouse-gas pollution has become a major challenge with the rapid increase in world population. Therefore, alternative energy sources have received increasing attention recently. In this respect, CO2-free combustion liquid e-fuels (OME, DMC), have considered as one of the most promising renewable clean fuels in automobile industry. However, engine performance, combustion characteristics and exhaust emissions are yet to be analyzed in details to obtain a clear understanding before implementing this alternative fuel in a wide scale.\nOur research scope focuses on soot emissions measurements in terms of soot particle sizing, volume fraction, specific soot properties and maturity. This work aims to apply non-intrusive laser diagnostics method. Laser-induced incandescence (LII) is one such diagnostic technique that is commonly used for flame soot characterization. Additionally, light extinction optical method will be utilized in combination with LII for quantitative soot volume fraction measurements.", "pred_label": "__label__POS", "pred_score_pos": 0.999226987361908}
{"content": "Digitalization doesn't just change individual businesses, it has an impact on the entire retail sector, enabling new and enhanced business models. Thanks to networked technology, the focus has changed from the product to the customer. Their requirements and wishes are at the foreground and make the current age the “Age of the Customer” for businesses. To do justice to this, brick and mortar retailers must play to their strengths – supported by digital solutions\nThe advantages of retailing are clear to see: tangible products, individual consultation, and a personal customer approach - nevertheless, the local store cannot remain the way it is. The customer's shopping experience has already begun at home, where they have already come into digital contact with your business on the couch, via the internet, or through the relevant app. Retailers are faced with the challenge of combining the advantages of brick and mortar business with a digital world of experience. Changing retail means using digital opportunities in your business too. This often requires an extensive digital transformation. The customer profits from this transformation through greater comfort and additional services - such as mobile payment via app or click & collect. The foundation for these is networked technologies and data analytics applications. This way, customer data, for example, can become a new resource for retailers. However, this requires a large degree of security.\nAll this makes one thing clear: brick and mortar retail is in the middle of the digital transformation. With an integrated omni-channel business model, it can continue to be competitive in the age of e-commerce.", "pred_label": "__label__POS", "pred_score_pos": 0.6292448043823242}
{"content": "During your free first consultation we will draw a blood sample which has a hormone specific panel designed by our hormone specialist. This blood test is critical in understanding how bioidentical hormone treatment may be applied for your case. We’ll get your medical history, activity level, and discuss your specific situation and how your symptoms are affecting your life.\nA second complimentary consultation will review your labs results, history and discuss your goals. At Age Reversal Medicine we want to get the entire story of you. Neither one size, nor one dose, fits all. Additionally, with BHRT (Bio-Identical Hormone Replacement Therapy) there can be additional supplementation which provides necessary balance. There may be some fine tuning needed to bring your bodies’ vitality, emotions, and performance levels back to spec and we are committed to stay connected with you ensuring the best experience.", "pred_label": "__label__POS", "pred_score_pos": 0.8547610640525818}
{"content": "Microbial synthesis of CuNPs using Brevundimonas diminuta strain and its antibacterial activity Mahesh H Joshi, Ashwini A Patil, Smita Chaudhary and Ravindra D Kale Abstract\nGreen synthesis of nanoparticles is an emerging nanoparticle synthesis method due to its simplicity and non-toxicity. In the present study, we report the ability of\nBrevundimonas diminuta strains obtained from mining soil to synthesize copper nanoparticles (CuNPs). These strains were isolated from mining soil, identified and characterised. A bacterial enzyme, which is a characteristic for this species, was isolated, centrifuged and the resultant supernatant solution was used for nanoparticle synthesis from CuCl 2. UV-visible spectrophotometer was used to assess the formation of nanoparticles. The size of the nanoparticles was verified using X-ray powder diffraction (XRD) and nanoparticle size analyser. Fourier-transform infrared spectroscopy (FTIR) was used to characterise the chemical nature of the reducing and capping agents present on the nanoparticles. Additionally, the effect of pH, time and concentration of CuCl 2 on the CuNPs formation was also investigated. The synthesised nanoparticles showed anti-bacterial activity. The favourable synthesis of stabilised CuNPs demonstrates the relevancy of the isolated Brevundimonas diminuta strain for its bulk synthesis.", "pred_label": "__label__POS", "pred_score_pos": 0.7502248287200928}
{"content": "Are you concerned about your lack of progress with GMP equalisation? Square™ provides end-to-end delivery of GMP equalisation in a clear and cost-effective way, ensuring quick compliance for you. Using our proprietary technology and methodology built into Square, we can deliver the whole GMP equalisation project as a stand-alone solution, from data analysis to the critical matter of communicating the impact to the scheme members.\nAn end-to-end solution to the challenges of GMP equalisation A pragmatic and robust approach to GMP equalisation\nSquare delivers a uniquely packaged, efficient, and innovative route to equalisation, rectification, and conversion, which incorporates:\nA fully integrated end-to-end process, which can be delivered as a standalone project, independent of a scheme’s existing adviser Cutting-edge, clear member communications Innovative technology, using our proprietary Janus method\nThe Square process benefits from unique end-to-end mapping, and is divided into four stages:\nFact find and initial advice Advice and decision on equalisation approach Calculation and implementation Communication\nEach stage comes with a checklist, a full suite of client advice material, and template communications.\nSquare places pension schemes well ahead of the curve, with positive results for members, trustees, and scheme sponsors alike.\nWhat sets us apart Proven track record\nSquare has a proven track record of enabling schemes to make significant progress with GMP equalisation, well ahead of others in the market. Buck is at the forefront of the industry in helping schemes on their GMP equalisation journey, leading the charge on the ‘call to action’ issued by the industry working group.\nInnovative technology\nAt the heart of Square is our proprietary technology, which has been built to offer a perfect balance between pragmatism and technical robustness. Our Square technology has a modular structure, designed to seamlessly link our administration and actuarial software to offer a single integrated GMP equalisation solution.\nProprietary calculation method\nOur calculations are based on our proprietary Janus method, enabling us to complete historical equalisation (and, as necessary, rectification calculations) by focusing on the additions/reductions to pension amounts, rather than the full nominal amounts, but without losing the granularity from sub-dividing and analysing the pension in detailed tranches.\nClear communications for all\nOur template member communications are certified jargon-free and focused on delivering the messages in a way scheme members can genuinely understand. In addition, we’ve developed a unique GMP equalisation scoreboard for trustees, which summarises the latest developments at a glance, providing effective governance over the project without unnecessary technical detail.\nResources Expertise at every turn.\nGet Square with Buck.\nIntroducing Square: a cost-effective solution to the challenges of GMP equalisation, ensuring compliance for your scheme, and clarity for your members.\nWe’re here to help you Square in action: Global pharmaceuticals company Square has been introduced as a standalone project to deliver GMP equalisation effectively and innovatively for a hyper-busy scheme with multiple stakeholders and workstreams. In just a few months, the scheme data is GMP equalisation-ready, transfer values have been equalised, and discussions on member communications are underway. This scheme is now in the top 5% for progress with GMP equalisation.", "pred_label": "__label__POS", "pred_score_pos": 0.7343975901603699}
{"content": "These days we hear about goals and to achieve it we must plan our daily activities. Organizing and planning your daily activities didn’t start in 20th or 21st century. It started way before that.\nWe often hear to write the daily affirmations and our end goals. This will help us get to our dream and make us successful both in mind, body, spirit and in surroundings.\nI was going through the Autobiography of Benjamin Franklin where I found that he, during his life time, was organizing his daily activities. He was allocating his time, by hours, on personal development, public and private business. He also had made prayer which he used to perform every morning to bring positivity in the day. It was though 18th century. He used his notebook to keep track of his short term goals and daily activities.\nAnd we(most of us) are still following it. We don’t exactly know when this started and when will it work. But the truth is it works.", "pred_label": "__label__POS", "pred_score_pos": 0.617646336555481}
{"content": "The United States is concerned about the disqualification of approximately 100 candidates for Burma’s upcoming general election, with over half of the cases rejected based on questions of citizenship.\nWe are aware of reports that almost all Muslim candidates have been disqualified — including some current members of parliament — yet the relevant authorities have yet to provide the specific reasons for which they did not meet these criteria.\nThese elections are vitally important for Burma’s people and its future. However, there are concerns about the constitutional provision that reserves 25 percent of parliamentary seats for the military and the disenfranchisement of temporary registration certificate holders. The move to disqualify some 100 candidates, through an opaque and discriminatory process, risks undermining the confidence of the Burmese people and the international community in these elections.\nWe urge the Burmese authorities to redouble their efforts to address these concerns and ensure that the upcoming elections constitute a step forward for the country.\nThis post is in: Press Release", "pred_label": "__label__POS", "pred_score_pos": 0.8996722102165222}
{"content": "The federal government is instructing nursing home staff to get vaccinated as soon as the COVID-19 vaccine becomes available. They are being asked to not wait for the vaccines to be available in the nursing homes in partnership with pharmacies such as CVS Health and Walgreens. These two pharmacies have partnered with the federal government to provide immunizations in nursing homes. The Pharmacy Partnership for Long-Term Care Program should not be the primary option for the staff, but instead more of a last resort. Staff should seek the immunizations from local clinics in the community.\nIt is anticipated by Centers for Disease Control (CDC) that there will be clinics set up for health care workers to receive the vaccine. Additionally, there will be agreements with pharmacies such as CVS or Walgreens to provide the immunizations.\nFor the long-term care vaccination plan, pharmacies will handle the process of the immunization for the nursing homes. This will include storing, distributing and administering the vaccines. The task force is ready to start the administration of vaccines in 24-48 hours once they receive the Emergency Use Authorization. The CDC is also trying to prevent operators from using their own LTC pharmacy partners for this effort as guidelines are stricter for the COVID-19 vaccine.\nProviders can choose to opt into the program by November 6\nth. Learn more here.", "pred_label": "__label__POS", "pred_score_pos": 0.9124920964241028}
{"content": "On October 15, November 8 and December 5, 2019, members of the Lac Ste. Anne County Council and Administration participated in strategic planning workshops to consider a future direction for the County and build a framework for a Strategic Plan for 2020-2023. The workshop objectives were to identify a shared vision for Lac Ste. Anne County; and the components of a strategic plan that would provide guidance to development of operational plans. The strategic planning horizon was for the next three to five years, with business plan goals extending three years, and operational plan objectives to guide the work of staff for one year.\nScope and Outcomes\nIn identifying the scope of the anticipated outcomes for these plans, participants agreed that the County had a strong organizational foundation that is operating well. While there were some lingering issues that needed to be addressed and brought to a conclusion, maintaining a consistent focus on a set of clear longer-term priorities would enable the County to achieve considerably more in the next five years.\nThe primary focus of the 2020-2023 Strategic Plan is to define strategic objectives with achievable outcomes that are distinct from the standard operating initiatives the County undertakes year after year. Because activities like budgeting and capital planning are undertaken during the regular course of work, there is no distinct outcome or completion point to these activities. While a vital part of municipal government, these activities are not in themselves strategic objectives. These plans will continue to be discussed and developed on a continual basis.", "pred_label": "__label__POS", "pred_score_pos": 0.8669669032096863}
{"content": "With new risks emerging almost daily, businesses have more blind spots than they often realize. Being financially insulated from these risks requires help from experts who can guide them through the complexities of the insurance industry.\nWhat are some of the most common areas where we can provide guidance?\nProperty Insurance – Buildings, Contents, Boiler & Machinery Time Element – Business Income, Loss of Rents, Extra Expense Inland Marine – Builders Risk, Machinery, Property in Transit Auto – Private Passenger, Trucking, Delivery, Livery Professional – E&O, Abuse, Technology, Engineering, Medical, Pastoral, Psychiatric, Nursing, Legal Management Liability – Employment Practices, Directors & Officers, Fiduciary Liability, Workplace Violence Cyber/Data Breach Crime – social engineering, phishing, 3 rd party, employee theft Surety/Bonding", "pred_label": "__label__POS", "pred_score_pos": 0.6164666414260864}
{"content": "A growing network of hospitals, rehabs, and outpatient surgical centers anticipated doubling in size in as little as six years. But they knew it wouldn’t be easy. The network lacked an Accounting SSC (shared service center) which would be required to efficiently support even its current size, to say nothing of its aggressive growth projections. The network asked Protiviti to determine the feasibility, cost, and benefit of establishing an SSC, and, ultimately, implementing such a solution.\nOur Protiviti/Robert Half team conducted an AP Transaction Analysis to understand and quantify the current profile, trends, and opportunities. Next, the SSC design and implementation was executed to optimize processes as well as the ongoing cost commitments. Then we hired, trained, and managed temporary and full-time staffers to operate the previously manual processes and implemented new user-friendly solutions for invoice workflow, implementation of EDI, ACH, employee expense, travel management, and E-payable solutions. As a result, Protiviti helped standardize accounting processes across the network in accounts payable, fixed assets, general ledger, cash, insurance, and intercompany functions. Bottom line: our efforts optimized headcount in accounts payable and general accounting functions, resulting in a $1.3 million savings, or a 24 percent payroll reduction, and reduced disbursement costs by implementing rebate programs resulting in returns of approximately $2M annually.", "pred_label": "__label__POS", "pred_score_pos": 0.610399603843689}
{"content": "de Vries, Anthonius W. and Portela, Clara and Guijarro-Usobiaga, Borja (2014)\nImproving the Effectiveness of Sanctions: A Checklist for the EU. CEPS Special Report No. 95, 6 November 2014. UNSPECIFIED. Abstract\nThe increasingly frequent imposition of sanctions by the EU over the past decade has not been accompanied by a thorough pre-assessment and contingency planning stage, which, argue the authors, has led to the formulation of suboptimal sanctions regimes. This paper proposes a practical pre-assessment and contingency planning of sanctions – a checklist, which departs from the ‘ad hoc-ism’ of current decision-making on sanctions. The checklist includes the identification of resources linked to the objectionable policies; the leverage of the EU; the costs to the EU; the legality of the measures; their unintended effects; the expected contribution towards EU goals; their coherence with overall EU external relations; and the communication of these policies.\nSocial Networking: Actions (login required)", "pred_label": "__label__POS", "pred_score_pos": 0.7791002988815308}
{"content": "The TDS Meter is capable of measuring total dissolved solids (TDS) and temperature. This instrument can provide three ranges, and has an autoranging function to select the most suitable range for testing.\nThe detection of total soluble solids is important for many applications, especially industrial and swimming pool waters. The TDS concentration has a significant proportional relationship with the conductivity. Therefore, the TDS detection is usually performed using an instrument for measuring the conductivity, and the results are converted to TDS when the results are displayed.\nA TDS probe is provided with the instrument to meet the requirements for laboratory use, and a portable soft pack is also provided for on-site operation and use.\nThe instrument can be calibrated individually within each range. If a range is not calibrated, the instrument automatically selects a calibrated range that is closest to it for measurement. The instrument can be calibrated using the BEHRINGER TDS standard.\nThe company specializes in the production and sales of various\nTDS Meter, welcome customers who have the need to consult and purchase. We will provide the best quality and service. Email: info@yingaolab.com", "pred_label": "__label__POS", "pred_score_pos": 0.6129554510116577}
{"content": "Metric competencies for biomedical librarians: results of a survey developed by the EAHIL Evaluation and Metrics group Abstract\nThe library profession continues to evolve and respond to user demands with both tools and services that support instruction and research. These changes typically lead to a need for increased librarian understanding and training. One such example is seen in the growing interest surrounding bibliometrics, altmetrics, and personal identifiers. Each of these serve as indicators of impact, and are becoming increasingly important in research. To more clearly identify and measure the current prevalence of each in the librarian profession, the EAHIL Metrics Group developed and disseminated a survey designed to capture current demand, and identify potential knowledge gaps where training would be beneficial. This publication presents the results of the survey and discusses pathways to attaining and providing increased expertise.\nThis work is licensed under a Creative Commons Attribution 4.0 International License.", "pred_label": "__label__POS", "pred_score_pos": 0.9300757646560669}
{"content": "A trust is a legal entity that contains a set of instructions on exactly how and when to pass assets to trust beneficiaries. Trusts can be used for various purposes, including as a will substitute to avoid probate, maintain privacy, minimize taxes, protect assets from creditors, and preserve assets for future generations.", "pred_label": "__label__POS", "pred_score_pos": 0.9966675043106079}
{"content": "Platelet-rich plasma (PRP) refers to a sample of serum plasma obtained from the individual’s own blood sample. The blood is injected into the injured area to stimulate healing.\nPlasma increases the cell renewal where it is injected, and wrinkle reduction is observed. It also provides a vivid appearance on the skin. To obtain good results, this method must be applied for three times within three-week intervals. It also supports and accelerates hair growth, when applied following to the hair transplantation. The combined use with the other skin renewal methods, its effectiveness increases.", "pred_label": "__label__POS", "pred_score_pos": 0.9535742998123169}
{"content": "Four phenylpropanoid glycosides lavandulifolioside 1, martynoside 2, verbascoside (=acteoside) 3 cmd leucosceptoside A 4, were isolated from aerial parts of Sideritis lycia Boiss. et Heldr. (Lamiaceae). Their structures were determined by chromatographic and spectroscopic methods (UV, IR, H-1-NMR, C-13-NMR, FAB-MS). These compounds and flavonoid glycosides isolated from the same plant in our previously study were screened for their anti-inflammatory activity using the carrageenan-induced mouse paw edema test. The active compounds were then investigated for their effect on gastric ulceration. Although flavonoid glycosides showed higher activity than the phenyl-propanoid glycosides, the gastric ulceration effect of phenylpropanoid glycosides was less than flavonoid glycosides.", "pred_label": "__label__POS", "pred_score_pos": 0.6158565282821655}
{"content": "Fitch Ratings has affirmed JSC Georgian Railway's (GR) Long-Term Foreign- and Local-Currency Issuer Default Ratings (IDRs) at 'BB-' with Negative Outlooks. A full list of rating actions is at the end of this commentary. The affirmation reflects Fitch's expectations that GR's link with the government will remain unchanged, while its debt metrics will commensurate with its Standalone Credit Profile (SCP) assessment at 'b+', leading to a single-notch differential of GR's IDR with Georgia's sovereign IDR (BB/Negative).\nAccording to Fitch, GR receives mostly non-cash and indirect state support. “Historically, support of GR's long-term development has been via state policy incentives and asset allocations. In addition, strategic infrastructure, such as railroads and transmission lines, is exempt from property tax in Georgia. GR enjoys greater pricing power than its Fitch-rated regional peers. GR's tariffs are fully deregulated, allowing tariffs in both freight and passenger segments to be adjusted to market conditions. Freight tariffs are set in US dollars, resulting in natural hedge for a company that operates in a country with a dollarised economic environment” – says Fitch.\nKey assumptions for the ratings case are two: operating revenue growth on average 3.9% in 2020-2024 and operating expenditures growth on average 4.9% in 2020-2024.\nAmong the factors that could, individually or collectively, lead to positive rating action/upgrade for the GR, Fitch considers a revision of the Outlook on the sovereign IDRs to Stable would result in similar rating action on GR; an upgrade of Georgia's sovereign rating, provided there is no deterioration in GR's SCP and support score under our GRE Criteria; upward reassessment of the support score and therefore removal of the rating-notch differential, and a stronger financial profile, resulting in the SCP being on a par with or above the sovereign's.\nAmong the factors that could, individually or collectively, lead to negative rating action/downgrade for the GR, Fitch considers a downgrade of Georgia's sovereign rating; dilution of linkage with the sovereign, resulting in the ratings being further notched down from the sovereign's, and downward reassessment of the company's SCP, resulting from deterioration of financial profile with net debt/EBITDA sustainably above 9x as per our rating case.\nFitch considers a potential default of GR on external obligations as potentially harmful to Georgia, as it could lead to reputational risk for the state. “Both GR and the state tap international capital markets for debt funding, as well as loans and financial aid from IFIs. This leads us to assume that a default of GR could negatively influence the cost of external funds for future debt financing of other GREs or the state itself. It could also significantly impair the borrowing capacity of the latter due to potential reputational damage and the small size of the domestic economy” – reads the statement released by Fitch Ratings.", "pred_label": "__label__POS", "pred_score_pos": 0.7863227128982544}
{"content": "If you operate a restaurant, you are likely to have ran into issues and frustration involving payment transactions. Payment processors that handle customer payments can be riddled with complex pricing models, poor support, and hidden fees.\nParTech Inc. believes it has a solution for the restaurant industry. The company has introduced a new all-in-one payment processing solution for restaurants.\nParTech Payment Services for Restaurants\nThe PAR Payment Services aims to turn the complexity and confusion of payment processing in restaurants on the head. Instead of paying multiple fees with ‘hidden extras’, restaurants pay one simple fee to PAR. Rather than leaving restaurants guessing, it is clearly stated within the fee what is included and not included.\nAddressing Customer Issues Quickly and Efficiently\nAnother leading irritation of payment processing within the restaurant sector is poor customer support. PAR Payment Services features PAR’s experienced and quality technical support team. The experts address all customer issues in a single call. This contrasts to what many restaurants are used to – being “passed from pillar to post.” With PAR, the frustration of multiple operators dealing with an issue is substituted with a single expert ensuring the problem is resolved.\nDCI and PA-DSS Compliant\nPAR Payment Services is compliant with DCI and PA-DSS, the Payment Application Data Security Standard. Such compliance ensures restaurants use reliable payment processing that protects consumer data through fraud and chargeback monitoring.\nPAR Payment Services include a Hardware Payment Plan. The plan eliminates upfront costs as restaurants pay for PAR hardware and services monthly. This could prove valuable during these testing times when many restaurants may be struggling with cashflow.\nRestaurants also have the freedom to choose their own payment device. The platform allows clients to select PAR Pay or from several pre-approved payment gateways and devices.\nPAR Payment Services’ single monthly fee covers everything from monthly statement fees to fraud and chargeback monitoring. It also covers portal access, batch fees and comprehensive technical support.\nImage: partech.com\nThis article, \"ParTech Launches All-In-One Payment Processing Solution for Restaurants \" was first published on Small Business Trends\nvia Small Business Trends Business Feeds", "pred_label": "__label__POS", "pred_score_pos": 0.8595396280288696}
{"content": "Synopsis\nParticipants will enter the world of visual images, where they will begin to see the meanings and messages behind the styles and decorative images one encounters today. They will discover the inner workings of interior design and understand the essential elements of design that enable one to identify what to look for when observing design in the world around us to better understand design. They will also gain the insights needed to be a first-rate interior designer, by using this new knowledge to create their own designs with enhanced flair and creativity.\nThe course will include the definition, interpretation, application, and evaluation of design elements such as scale, texture, tone, harmony, rhythm, and connotations of space, to enhance visual literacy. This will enhance the participants’ awareness of design elements and how they are applied, in the broader sense, in the everyday world.\nThe course will also cover the essential underpinning knowledge, skills and attitudes required to establish criteria for the appropriate and effective evaluation of designs including aesthetic considerations, social and cultural context, and exploration of the narrative of design through a critical evaluation of existing examples.\nAim of the Course\nTo develop observation, interpretation and analytical skills to facilitate the exploration of design principles in a theoretical and applied approach. The course also aims to provide students with knowledge, skills, and the necessary attitudes to increase their range and variety of creative options in the process of conceptualising, developing and justifying creative concepts for interior design projects.\nLearning Objectives\nParticipants who successfully complete the program will be able to:\nDevelop and apply the research criteria to analyse and critically evaluate selected designs. Synthesise and apply strategies for developing and exploring creative design options. Produce a creative interior design solution for a commercial and residential interior. Duration of the Program\n6 sessions at 2 hrs per session (Total of 12 hours).\nMinimum Number of Students Before a class Commences\nMinimum 6 students are required before the commencement of Classes.\nFacilitation Resources and Aids Needed\nParticipants are advised to bring along with them:\nStationeries include an A4 Notebook with Pens. Laptop with software download advised by the school course administer before the commencement of course. Attire\nNeat Casual wear (e.g. collar t-shirt, sweater, long trousers or jeans, sports shoes, etc.)\nCourse Fees\nGroup Class: $395.00. Bring a friend and enjoy a special rate of $700.00 for 2 pax.", "pred_label": "__label__POS", "pred_score_pos": 0.7538880705833435}
{"content": "Keeping your residential awnings clean and free of debris will extend the life and vibrancy of your awning’s fabrics. Once a month hose the awnings with clean water, this helps prevent stains from setting and reduces the amount of more intense cleaning. However, a deep clean every 2 and a half years will be required.\nLight cleaning quick guide.\nRemove any loose dirt or debris to prevent damaging the fabric and awning. Using clean water hose down the awning, it doesn’t need to be heavily saturated. Combine water and dishwashing fluid, enough to be generous in application to the awning. Apply the cleaning solution to awning using a brush or towel ensuring that the solution penetrates the fabric. Using a hose rinse the fabric to prevent soil residue stains. Allow the awning fabric to air. Follow this monthly routine will keep your residential awning looking good as new and ensuring it lasts a lifetime.", "pred_label": "__label__POS", "pred_score_pos": 0.987079381942749}
{"content": "Abstract\nTo achieve success in educating visually impaired children in general educational settings, best-practice initiatives should be established before implementation occurs. This article examines the literature on early childhood special education and education of children with visual impairments to suggest practical guidelines for integrating youngsters who are blind or visually impaired with their age-appropriate peers.\nOriginal language English Pages (from-to) 253-260 Number of pages 8 Journal Journal of Visual Impairment and Blindness Volume 85 Issue number 6 State Published - 1 Jan 1991", "pred_label": "__label__POS", "pred_score_pos": 0.7324030995368958}
{"content": "Trauma-Based Therapy\nVarious forms of trauma-based therapy can be implemented to help individuals heal from traumatic life experiences.\nThese approaches typically begin with psychoeducation to help clients understand their symptoms.\nThis treatment offers a safe space to process experiences, guides clients in learning new strategies for coping, and supports them in re-creating a sense of security while reinforcing resilience and empowerment.\nAll clinicians at TPWG have training in the treatment of trauma and adopt a trauma-informed lens to supporting clients in managing their presenting concerns.", "pred_label": "__label__POS", "pred_score_pos": 0.9999838471412659}
{"content": "Concentra's self-service portal provides employers, workers’ compensation payors, and third-party administrators (TPAs) quick access to account information and visit results through a single automated system.\nThe US Department of Transportation issues regulations that employees working in various aspects of transportation must meet. This includes all modes of transportation and industries associated with transportation, including road and railway construction. Employers must ensure their employees meet the proper regulations for their specific job to be compliant with local, state, and federal regulations.\nWhat It Means for Employers\nBy staying current and compliant on all DOT regulations, employers can ensure a safer and healthier workforce, as well as reduce the risk of on-the-job injuries and fines. Employers must also comply with DOT regulations to ensure safe working conditions and proper precautions are being met to protect employees and the greater public.\nNew FMcsa Insulin-treated Diabetes Rule\nNo more long delays for commercial drivers with insulin-treated diabetes waiting for a federal exemption. A new Federal Motor Carrier and Safety Administration (FMCSA) rule has ended the exemption program. The driver’s treating clinician is now responsible for determining if the driver’s insulin regimen is stable and his or her diabetes is properly controlled. A new form, Insulin-Treated Diabetes Mellitus Assessment Form MCSA-5870, will be required by medical examiners to issue the Medical Examiner’s Certificate (MEC).\nConcentra’s Expertise\nConcentra provides DOT physical exams for employers who operate in various industries, including:", "pred_label": "__label__POS", "pred_score_pos": 0.6848399043083191}
{"content": "It should be noted that enforcing the Convention is not absolute, given it expressly excludes matters such as family law, estate law, bankruptcy, slander, privacy, intellectual property, as well as arbitration and related proceedings.\nAs of this date, the Convention is available for signing. Uruguay became the first party to the treaty, and for it to take effect, it is necessary that at least another country sign and ratify it. Once in force, any state may join.", "pred_label": "__label__POS", "pred_score_pos": 0.9990131855010986}
{"content": "If you don't like ...\nI’m always amazed at the short-sighted reasoning of those who don’t know the length of their own reach — as in, “Your right to swing your arm ends where my face begins.” (Even that could be uncomfortably close.)\nTheir reasoning goes this way: If you don’t like pornography, don’t watch. If you don’t like alcohol, don’t drink. If you don’t like abortion, don’t have one. By the same reasoning one could add: If you don’t like murder, don’t commit one. If you don’t like drunk driving, don’t drive drunk. If you don’t like robbery, don’t rob. If you don’t like terrorist bombings, don’t participate. The rest of us should be free to do what we want.\nAlmost everything my neighbors do affects me in one way or another. I believe in as much liberty as possible for ALL of us. For example, I don’t care if you cycle without a helmet as long as I don’t have to pay tax money to scrape you off the pavement and/or pay for your hospitalization and rehab.\nIf there is any reliable data showing that pornography is\nnot a public mental/social/emotional health problem, I have yet to see it. Everything I’ve read is negative.\nMargaret Leigh\nSt. George", "pred_label": "__label__POS", "pred_score_pos": 0.9863729476928711}
{"content": "During our inspections, we still find many older homes in Columbus have Knob and Tube Wiring. This type of wiring is a fire hazard and should be removed and replaced with new wiring by a qualified electrician.\nThe system is comprised of wiring supported with ceramic knobs with tubes that run through the wood joists and framing and at locations where the wires intersect. Knob and Tube wiring is considered unsafe for several of the following reasons:\nIf you have any concerns about Knob and Tube wiring in your house, contact us to speak with a qualified home inspector.", "pred_label": "__label__POS", "pred_score_pos": 0.8442447185516357}
{"content": "Colorado Tops List for Biggest Unemployment Increase During COVID-19\nWith the U.S. losing over 22 million jobs since the start of the COVID-19 pandemic, WalletHub has released updated rankings for the States with the Biggest Increases in Unemployment Due to Coronavirus.\nTo identify which states’ workforces have been hurt most by COVID-19, WalletHub examined the amount of unemployment claims filed in each state, as well as the District of Columbia. This update includes their latest comparisons from the week of April 6 and their overall summation since the pandemic started deeply impacting America on March 16.\nIncrease in Colorado Unemployment Due to Coronavirus (1=Greatest Increase, 25=Avg. Increase):\nAccording to WalletHub, Colorado has experienced the greatest increase in unemployment over the past week, though we are only the 20th most-impacted state since the overall crisis began. That dubious honor goes to New Hampshire, whose unemployment claims have gone up by 6429.42% this April since the start of the crisis.\nStill, here's how our results break down. We've experienced:\nA 5,058.22%increase in unemployment claims since April of 2019 According to WestWord, that means 105,073 claims were filed the week of April 6, 2020, while only 2,037 were filed the week of April 8, 2019. That puts us at the 4th highest increase in unemployment claims in the U.S. since 2019. A 4,222.21%increase in the number of unemployment claims since 2020 began This gives us the 2nd highest increase in the U.S. this year, while Louisiana holds the spot at number 1. A 3,341.62%increase in unemployment claims since the pandemic started According to CPR, that increase means there's been about 80,558, unemployment claims since March 14. This, in turn, has us experiencing the 20th highest increase in unemployment in the U.S. since the COVID-19 economic crisis began.\nEssentially, this makes the storm we're currently weathering at least twice as difficult as those we experienced during the Great Recession.\nHowever, as bleak as these numbers seem, and we know they're deeply concerning, we will find our way through. Look out for each other, and help where you can.", "pred_label": "__label__POS", "pred_score_pos": 0.7146673798561096}
{"content": "TVSquared Releases Automotive TV Advertising Performance Report TV Is Leading the Category for Automotive Attribution – Analysis Uncovers Strongest Response for 15-Second Spots and Daytime TV\nTVSquared, the global leader in linear and digital TV attribution, released its report, “Taking Back the Wheel: TV Ad Performance Insights for Automotive Brands.” The analysis uncovers the TV buy elements that are driving response spanning KPIs, creative lengths, programming genres, days and dayparts for the auto industry.\nTVSquared analyzed more than $10 billion in TV ad spend from nearly 200 auto brands during H1 2019. Response, cost and audience data from TVSquared’s always-on ADvantage analytics platform was evaluated to find the highest and lowest performing buys, providing auto advertisers with invaluable insights into spend efficiency and effectiveness. Key findings featured in the report include:\nAnimation was the most effective genre for response; while Sports was the most popular genre, despite continually delivering average results. 15-second spots had a cost per response (CPR) 25% lower and a response rate 50% higher than traditional 30-second ads. The highest response rates were seen during Daytime TV – +33% during weekends and +21% during weekdays. Mondays performed the least effectively, and were +18% more expensive in delivering response vs. other days.\nMark Hudson, Head of Business Intelligence at TVSquared, who spearheaded the report, said:\n“This is essential reading for auto advertisers, providing strategic guidance to leverage TV ad spend effectively at the global, national and local levels. Amid pressure to maximize ad spend, attract new buyers and secure future growth, auto brands should focus on middle- to down-funnel KPIs for their TV ads to drive response – such as locating dealerships or engaging with new car configurators. A user’s journey to purchase a car can take weeks or months to complete, so measuring these types of responses gives brands insightful and quantifiable indicators of TV performance.”", "pred_label": "__label__POS", "pred_score_pos": 0.9415727257728577}
{"content": "While you may have some idea of what an assault crime looks like, you not know what the term “menacing” means. In New York, you can face criminal charges for making verbal threats—even if you never made physical contact with the alleged victim. Depending on the specifics of the alleged incident, you could face a number of menacing charges, which are considered assaultive offenses under the state’s penal code. Let’s take a look at what menacing offenses are and what steps to take if you have been charged with these assaultive offenses in the New York area.\nThe Legal Definition of Menacing in New York\nAccording to New York state penal code section 120.15, menacing occurs when a person “intentionally places or attempts to place another person in fear of death, imminent serious physical injury or physical injury.” This definition is similar to assault, except that assault involves actual physical contact. Essentially, menacing in the third degree is verbally or nonverbally indicating your intention to cause harm to another person, even if you do not act on these threats. If you make such threats while displaying a deadly weapon, repeatedly engage in the course of conduct, or violate an order of protection, you could be charged with menacing in the second degree, which carries more significant consequences. Menacing in the first degree, the most serious menacing offense occurs when a person commits the crime of menacing in the second degree and has already been convicted of this same crime within the last ten years.\nHeated Arguments Can Trigger Menacing Charges\nIt is easy to get carried away in the heat of an argument, and people can make threats that they do not intend to fulfill. Unfortunately, such statements can trigger criminal charges, even if you did not ever mean to cause physical harm to the other person. If the accuser decides to report the incident to the authorities, the situation can escalate quickly. Suddenly, a few empty words you said while in an intense emotional state are being used to build a criminal case against you. In menacing cases, the account of the accuser can be sufficient to secure a conviction. If you are found guilty, you could face jail time, a damaged reputation, along with other negative consequences.\nLegal Counsel to Combat Menacing and Assault Charges in Queens\nCases involving menacing and assault crimes can be delicate, so it is essential that you contact a skilled criminal defense attorney right away to discuss your situation. Avoid “talking your way out of” being arrested; remember that any words you say, even if you are trying to tell the truth, can be twisted and used against you in court. Instead, wait until you have spoken with your attorney before you explain yourself to anyone else. Together, you and your lawyer will determine the best path forward to help you secure a favorable outcome.\nIf you are facing menacing or assault charges in Queens, contact the Law Office of Adrienne D. Edward, P.C. at (347) 997-3811 to discuss your options with a trusted New York criminal defense attorney.", "pred_label": "__label__POS", "pred_score_pos": 0.69510817527771}
{"content": "The treatment rates vary depending on the product. All additives have directions on the back label. They may also be used in about the same proportions in smaller fuel tanks. However, any additive added to 2-cycle fuel is treating the gasoline, not replacing the oil. Add the full amount of oil recommended by the engine manufacturer. For clarification or technical assistance, call 1-855-888-1990.", "pred_label": "__label__POS", "pred_score_pos": 0.8456374406814575}
{"content": "In my encounter with the Latino communities on Eastern Long Island, I reflected on how people express their faith beliefs and its foundations. When I met the laity at Eastern Long Island, I asked myself:\n“How I believe people have a natural inclination to believe and seek convictions to enlarge the meaning of their lives.” Yet, there is much we can do to help our people approach Jesus as one who revealed the true God, offering us a liberating and empowering love. This is a challenge with more questions than answers. Another challenge is this: how can I help our people seek freedom from ideologies that hinder encounter with the liberating Jesus?\nFinally, I saw theology applied in active ministry through the example and activities of my fellow Vincentian priests. They are truly committed to bringing the Good News to a people who, in this time of uncertainty, need help trusting the saving presence of God. I am grateful for my ministry experience with the Latino community on Eastern Long Island.\nc.", "pred_label": "__label__POS", "pred_score_pos": 0.9994626641273499}
{"content": "They engage in initial needs assessments, which is used to frame their work. They meet with school leaders and teachers, observe classrooms, and gather information to inform detailed, written action plans that respond to the school’s goals. Through full-day and/or half-day visits, coaches support teachers and school leaders with instruction, curriculum planning, and assessment design across content areas.\nWe also plan and facilitate school-based and off-site workshops designed to meet the specific needs of a given partner school. Our workshops are half-day, full-day, and multi-day and are designed and led by our team of coaches drawing on their vast experience working with pre- and in-service teachers and expertise spanning content areas.", "pred_label": "__label__POS", "pred_score_pos": 0.5222613215446472}
{"content": "I hated discipline. Every form of it. Until I learned that disciple is not punishment.\nGrowing up we were punished for every slight infraction we made in my father’s kingdom. If you spoke or behaved inappropriately, a leather belt was waiting to connect to your raw skin. If you didn’t wash the dishes just right or left the sink dirty, you were woken up to his screaming, made to get out of bed and come down and correct it by washing ALL the dishes.\nAny infraction, after he delivered his punishment, was underlined with his silent treatment for hours, days, weeks – depending on how much he wanted you to suffer.\nI mistakenly believed my father’s actions were discipline.\nDiscipline means by definition the practice of training people to obey rules or a code of behavior, using punishment to correct disobedience. This is not God’s defined method.\nI believe the discipline of the bible is a code of ethics you find through God’s love and exercising your own self-discipline.\nIt is nothing another person imposes on you. That would be the righteous rules of religion. That’s not God either. God could always discipline us, but He doesn’t.\nInstead, God pours out His love on us. He doesn’t discipline us like He should. God knew my story so He knew what I struggled with. He knew that I wanted to be more and He saw my genuine struggles.\nI cannot recall a time where God disciplined me for struggling with sin or change or understanding. When I struggled, that is when I have felt Him the most. He poured out His love even stronger and helped me understand His grace.\nEverything I once knew in life to survive, I have had to unlearn and retrain myself in the ways and standards of love.\nMy earthly father’s rules made me feel unworthy and that everything I did was wrong. The stamp of condemnation was forever coming down on me.\nMy Heavenly Father is all about His kingdom of love, grace and mercy. His rules are derived from the nature of Himself and He is love.", "pred_label": "__label__POS", "pred_score_pos": 0.7600523829460144}
{"content": "Answer\nPatients with obstruction in this setting will present with renal colic that may worsen after fluid intake. The pain can be confirmed on examination by flank palpation or percussion. Diagnosis involves imaging with modalities similar to those used for nephrolithiasis. Specialized studies to assess renal function and drainage are also often employed. A urologist should be consulted for treatment, which involves drainage of the obstructed proximal urinary tract and often provides immediate relief. See Ureteral Stricture for more information.", "pred_label": "__label__POS", "pred_score_pos": 0.9705560803413391}
{"content": "Digital transformation is a human and organisational transformation and technological opportunity represents only one dimension of the social evolution. The digital age has led to the transformation of service models and modes of collaboration and is challenging the way organisations work. Consequently, this must be seen as an opportunity to adapt and stay relevant in changing times.\nPerformance for large organisations with a long history means adapting to new market expectations, renewing customer portfolios and revolutionizing uses. Responding to these new challenges entails transformation of skills using available means, boosting agility and creating a sense of uniqueness and competitiveness.\nHuman capital, a driving force for transformation\nThe company must win and gain support of its employees by leading them to believe in its purpose and future vision and aim to create a digital experience for them which is on par with that of the customer. It is therefore crucial to introduce collective intelligence practices, adopt new methods, tools, organisations and attitudes for ensuring success.\nOur approach is centered around involving and developing employees in the strategy and operational modes of transformation. This objective goes beyond the internal human capital, i.e. if mobilised, the \"external\" ecosystem, can contribute towards the transformation of companies, accelerate performance and thereby lead towards concrete actions.\nAll company functions are required to address these transformations and actively contribute in redefining the value of the organisation. This applies for their own operations and cross-functional interactions and to achieve this, several levers of action and change management plans have been set up to accelerate this reinvention.\nFostering collective intelligence is crucial for a transformation. It is therefore important to rely on innovative and agile governance models, learning plans for collaborative methods and approaches, development of new role models and expansion of transversal networks. Companies need to inculcate a collaborative culture by maximizing talent so as to be able to respond to changing customer expectations.\nTogether, we increase your ability to leverage human capital by placing your people at the centre of strategy and execution.\nReinventing your organisation’s HR value chain models and employee experience together\nThe HR must rethink its transformational value and the ways in which it contributes to companies. Simultaneously, it must free itself of activities with low added value. We are here to help you redesign your skills transformation strategy to continuously adapt to these challenges.\nTo achieve this, required behavioural changes and new ways of working need to be introduced. We work with you to align the level of your employee experience, right from the recruitment stage and strive towards offering a great customer experience by designing, implementing and organising the execution of this transformation. Our teams offer their insights, experience and skills to meet your challenges and extend their support in redefining the roles, organisations and resources of your HR department.\nWe mobilise human resource information systems (HRIS) adapted to your specific needs through Sopra HR Software solutions, while remaining on the cutting edge of technology. Lastly, we inspire and develop your plans to leverage collective intelligence for accelerating transformation, improving employer branding and showcasing your talents.\nTogether, let us rise to the challenge of human transformation to confront changing patterns, cultures and skills.", "pred_label": "__label__POS", "pred_score_pos": 0.753261387348175}
{"content": "A small survey of global library staff reveals that respondents view open access as the future of academic and scientific publishing, and many are not satisfied with the current speed of the transition.\nThe survey collected opinions from approximately 200 respondents who work in research institutions or libraries, and whose responsibilities relate to scholarly communications, institutional policy, funding administration, research data or publication management.", "pred_label": "__label__POS", "pred_score_pos": 0.9909801483154297}
{"content": "Tax Planning Overview Tax Planning is the gear focused on minimizing federal and state tax liabilities compliant with tax laws. Our on-staff CPA, Chartered Financial Analyst, and Financial Planner Professionals™ can manage portfolio decisions on a real-time basis. APS incorporates all other components of your wealth management plan used to develop your customized portfolio and identifies opportunities for wealth accumulation, preservation, and tax avoidance.\nTaxes are often only considered during tax filing season, which is usually too late to act on opportunities that can minimize your tax burden. APS can proactively determine the tax impacts of investment decisions focusing on tax minimization. For retirees, APS can provide guidance on tax efficient sources of cash flow. We can also seamlessly coordinate with other professionals to reconcile your tax planning strategies with your overall investment and personal wealth planning goals.", "pred_label": "__label__POS", "pred_score_pos": 0.7466540336608887}
{"content": "Six Pennsylvania universities sent the following letter to the state's Congressional delegation in response to the SEVP guidance limiting online learning for international students.\nDear Pennsylvania Colleagues,\nWe write on behalf of our respective Pennsylvania universities to respectfully share the attached Dear Colleagues with you and ask you to consider signing onto one or more of the letters they are circulating to DHS Acting Secretary Chad Wolf, or writing a separate letter to him (draft attached for your consideration), in response to this week’s ICE rule that would deport international students enrolled at schools that are shifting to online only courses in the fall. The rule would require universities to make this determination by next week. (We apologize to, and thank, those of you who may have already signed onto or written letters as there are a number of them in circulation and they are continually being updated.)\nWhile we are all eager to reopen our campuses and are incurring significant costs associated with these efforts as we attempt to ensure the safety of our students, staff and faculty in the face of the ongoing uncertainties of COVID, this unexpected rule is creating an additional layer of uncertainty, cost and administrative burden, for students as well as for universities who must review students’ SEVIS records and decide if they will be offering only online classes in the fall and then inform the students they must leave the country in that case. All within a week. This is neither feasible nor necessary.\nICE should stand by its March guidance which stated that the status of foreign students would be protected for the duration of the pandemic crisis. Universities have repeatedly requested that the flexibility provided in guidance for the spring term be extended, not limited, for the fall term. The flexibility enables international students learn during this global health pandemic so they may continue progress toward their degrees, remain safe consistent with state and federal health officials recommendations, and ultimately contribute to our institutions’ learning environments, the nation’s innovation and discovery, and global competitiveness.\nThis announcement comes too late for many students to consider the possibility of transferring to another institution. Many institutions are starting classes in mid-to-late August. Additionally, international students who cannot transfer may find it difficult to leave the country due to a limited number of international flights. Many international flights that are available are expensive and further, students may be subject to travel restrictions that other countries have put in place. Their health will also be placed a risk by forcing them to travel when they otherwise would not be. In addition, this guidance could force international students to attend in-person classes while ill for fear of deportation proceedings should they halt their class attendance.\nEven for those institutions that are attempting to provide a hybrid course model in the fall, there is always the risk that they may be subsequently ordered by their local or state government to cease or restrict in-person learning options due to a COVID-19 outbreak.\nWe deeply appreciate your consideration of this request and urge you to reject this untimely and ill-considered action.\nSincerely,\nCarnegie Mellon University\nLehigh University Penn State University Temple University University of Pittsburgh University of Pennsylvania", "pred_label": "__label__POS", "pred_score_pos": 0.6454355716705322}
{"content": "Lease Accounting 9 Months Ended\nSep. 30, 2020\nLeases [Abstract] Lease Accounting\nLease Deferrals and Abatements\nUpon the temporary closure of theatres in March 2020, the Company initiated discussions with landlords to negotiate the deferral of rent and other lease-related payments while theatres remained closed. These discussions and negotiations have remained ongoing as the Company continues to be impacted by the COVID-19 pandemic. The amendments signed with the landlords involve varying concessions, including the abatement of rent payments during closure, deferral of all or a portion of rent payments to later periods and deferrals of rent payments to later periods combined with an early exercise of an existing renewal option or extension of the lease term. In some cases, the Company is entitled to rent-free periods while theatres remain closed in certain locations due to local regulations. Total payments deferred as of September 30, 2020 were approximately $62,559 and are included in accounts payable and accrued expenses in the condensed consolidated balance sheet.\nIn April 2020, the FASB staff released guidance indicating that in response to the COVID-19 crisis, an entity would not have to analyze each contract to determine whether enforceable rights and obligations for concessions exist in the contract and can elect to apply or not apply the lease modification guidance in Topic 842 to those contracts. The election is available for concessions related to the effects of the COVID-19 pandemic that do not result in a substantial increase in the rights of the lessor or the obligations of the lessee. For example, this election is available for concessions that result in the total payments required by the modified contract being substantially the same as or less than total payments required by the original contract.\nThe Company elected to not remeasure the related lease liabilities and right-of-use assets for those leases where the concessions and deferrals did not result in a significant change in total payments under the lease and where the remaining lease term did not change as a result of the negotiation. For those leases that were renewed or extended as a result of the negotiation to defer rent payments, the Company recalculated the related lease liability and right-of-use asset based on the new terms. During the three and nine months ended September 30, 2020, the Company did not recognize a material amount of negative lease expense related to rent abatement concessions.\nThe following table represents the Company’s aggregate lease costs, by lease classification, for the periods presented.\nThe following table represents the minimum cash lease payments included in the measurement of lease liabilities and the non-cash addition of assets for the periods indicated.\nAs of September 30, 2020, the Company had signed lease agreements with total noncancelable lease payments of approximately $220,417 related to theatre leases that had not yet commenced. The timing of lease commencement is dependent on the completion of construction of the related theatre facility. Additionally, these amounts are based on estimated square footage and costs to construct each facility and may be subject to adjustment upon final completion of each construction project. In accordance with ASC Topic 842, fixed minimum lease payments related to these theatres are not included in the right-of-use assets and lease liabilities as of September 30, 2020. There were no noncancelable lease agreements signed, but not yet commenced, related to equipment leases as of September 30, 2020.\nX\nX\n- Definition\n+ References\nThe entire disclosure for lessee entity's leasing arrangements including, but not limited to, all of the following: (a.) The basis on which contingent rental payments are determined, (b.) The existence and terms of renewal or purchase options and escalation clauses, (c.) Restrictions imposed by lease agreements, such as those concerning dividends, additional debt, and further leasing.\n+ Details\nReference 1: http://fasb.org/us-gaap/role/ref/otherTransitionRef", "pred_label": "__label__POS", "pred_score_pos": 0.7217864990234375}
{"content": "Human activities are rearranging the distribution of elements and species across the globe, but the consequences of these alterations remain unknown. Coastal ecosystems are likely at risk to an increase in intensity and frequency of large tropical storms, which can deposit large amounts of calcium and sodium. Little is known, though, how additions of these micronutrients can affect the success of consumers, especially litter arthropods. To determine how changes in biogeochemistry affects arthropods, we utilized a factorial, fertilization experiment that manipulated macro- (N&P) and micronutrients (Ca, K, and Na; 16 treatments x 8 replicates = 128 plots), in 2016 and 2017, in large 30m x 30m plots in a coastal tallgrass prairie near Houston, TX. We collected litter arthropods using pitfall traps in 2017, and one-year post-fertilization in 2018. Based on results from 2017, we conducted feeding trials, that manipulated the ratio of Ca:Na (by 10%, 25%, and 40%) in food, on an invasive ant, Nylanderia fulva in 2018. In 2017, N. fulva was the dominant litter arthropod across all treatments, and their abundance was limited by Ca, but tends to be suppressed by Na. In 2018, however, these effects disappeared, and abundance of N. fulva dropped 98%, likely due to Hurricane Harvey. Preliminary lab results indicate that Na can reach toxic levels, suppressing colony size, while Ca ameliorates these toxic effects. These results indicate that changes in micronutrient availability may facilitate the success of an invasive species and gives insight as to how human activities are altering coastal ecosystems.", "pred_label": "__label__POS", "pred_score_pos": 0.5712873935699463}
{"content": "During this period, the rate of violent deaths per 100,000 inhabitants maintained the downward trend of the current decade.\nBy the end of 2019, it reached 21.5, representing the lowest rate of the entire period and almost levelling with the Latin American average (20.1). The reduced rate exceeds the target proposed by the Government’s 2016-2020 General Policy, which was to achieve a rate of 23.5 by the end of 2019.\nSince 2010, the\nviolent death rate has been following a steady downward trend. It has fallen by about half, from 41.8 in 2010 to 21.5 in 2019, representing a drop of 20.1 points.\nAlmost half of the victims of violent deaths in 2019 were\nyoung people between the ages of 18 and 30. The rate of violent deaths for this age group is 41.2 per 100,000 inhabitants, almost double the national rate.\nIn 2019, 85 out of every 100 victims of violent deaths were men. These male deaths decreased by almost 9% compared to 2018. Female violent deaths accounted for 15.4% of all fatalities in 2019 and decreased by only 3.2% compared to 2018. The overall proportion of female victims has increased from 11.1% in 2012, to 15.4% in 2019.\nThere were 33.2% fewer homicides in the first four months of 2020 than in the same period last year.\nThe overall incidence of crimes recorded in 2019 increased by 6.9% compared to 2018. This was mainly due to an increase in incidences of extortion, which rose from 29,497 in 2018 to 31,540 in 2019. Most worrying is the fact that in 2013 extortion accounted for 15% of all crimes, while in 2019 it accounted for almost half of the total number of crimes recorded by the PNC.\nSince 2013,\nthe number of reported extortions has practically tripled, which could be a result of increased trust in institutions, improvements in reporting mechanisms or a genuine increase in the criminal act.\nNevertheless, with the exception of the aforementioned extortions,\nincidences of all other crimes decreased compared to the previous year. The number of injuries has historically been higher than the number of homicides, but in 2019 there were fewer injuries than reported homicides.\nWomen experience a higher incidence of disappearances, rapes and domestic violence than men.\nIn contrast, the data on robberies and thefts showed 51.1 victims per 100,000 inhabitants, of which 8 out of 10 victims were men. Furthermore, 7 out of 10 robbery victims were aged between 18 and 40 years old.\n_____", "pred_label": "__label__POS", "pred_score_pos": 0.5342725515365601}
{"content": "Most countries pay substantial intergovernmental transfers to poor regions with the aim of achieving regional convergence. Consequently, transfers should have a positive effect on economic growth. However, it is equally possible that transfers perpetuate underdevelopment. This paper studies empirically the effect of intergovernmental transfers on economic growth with a panel of West German states over the period 1975–2005. The findings suggest that transfers do not foster economic growth, presumably because the recipients use them to subsidize declining industries.\nBaskaran, Thushyanthan, Lars P. Feld, and Sarah Necker. „Depressing dependence? Transfers and economic growth in the German states, 1975–2005.“ Regional Studies 51.12 (2017): 1815-1825.Download full paper here.", "pred_label": "__label__POS", "pred_score_pos": 0.5072581768035889}
{"content": "Screw versus Cemented Implant-Supported Restorations\nChristopher C.K. Ho\nAn implant-supported restoration can be inserted onto an implant by either attaching it to the implants with screws or cementing it onto abutments that have been secured by screws. There are advantages and disadvantages to each procedure, and the decision of whether to screw retain or cement a restoration is often dependent on the implant position and clinician preference.\nThe factors that determine the decision are outlined in the following sections.\nScrew retention allows the ability to remove a restoration for repair, prosthetic modification or soft-tissue inspection, and creates access for hygiene if required. Many clinicians prefer to treat implant restorations similarly to conventional crowns and bridgework, cementing the final restoration and, if there is any maintenance required such as screw loosening, then destroying the restoration and replacing it accordingly. The incidence of screw loosening has diminished with improved screw-joint mechanics and connections, although it may still occur. When abutment screws loosen, cement-retained restorations are not always predictably removed from abutments to allow screws to be re-tightened, and hence the restoration may need to be removed. This would often destroy the restoration and render it unusable. Thus it would be prudent and simpler to manage if the restorations were planned for screw retention where, if a problem did occur, the restoration could be accessed through the screw hole, removed and tightened. Additionally, as the complexity of the restoration and the number of units increase, the expense of re-making an extensive restoration becomes untenable for the patient, so retrievability is paramount. Alternatively temporary soft cement can be used to cement the final restoration, this will require an accurate fit of the restoration to minmise the risk of inadvertent decementaion and preserve retrievability.\nScrew retention requires a screw-access hole to be made through the restoration that is normally restored with composite resin once the restoration is in place. In the anterior region of the mouth screw retention may not be possible due to implant position, as having a screw access in a visible area, such as the labial face of a maxillary incisor, is unacceptable (Figure 11.4.1). When screw access to the implants is in aesthetic areas, the screw access can be re-aligned with the use of angulated abutments, or the restoration should be retained with custom abutments and cemented. Screw-retained restorations can only be used when the trajectory of the implant allows the screw access to be in a non-aesthetic area. There are also clinicians who object to having a hole in the restoration that is restored with composite resin, as this may wear and discolour over time. Additionally, to achieve screw retention in the anterior region often involves aligning the implant slightly more palatally in the anterior maxilla to allow screw access in the cingulum area, which may leave a ridge lap or unaesthetic crown.\nA passive fit is desirable for implant restorations, as stress to an implant may overload the prosthesis, causing a technical complication, or lead to strain between the bone interface and implants, resulting in peri-implant bony changes. It has been advocated that one of the advantages of cement-retained restorations is that frameworks are more passive, as the abutments are individually retained to the implants by screws and the restoration is cemented over the abutments. This cement space allows for passivity, on the assumption that the cement acts as a shock absorber and reduces stress to the bone and implant interface. There is very little evidence to support this theory, however. Impression taking and handling of the casts are crucial to minimise errors and the advent of CAD/CAM milling has eliminated many of the errors from casting and metal work. Due to the passive fit, there is a belief that there is less fatigue and fracture of componentry, and that should there be overloading forces to the restoration, the cement layer would fail first, thereby saving the implant and restoration from failure.\nTo achieve screw access in maxillary anterior implant restorations, it may be necessary to align an implant in a more palatal trajectory, which may leave the implant more palatally placed, especially in a resorbed alveolar ridge. The final restoration may thus possess a ridge lap and subsequently be more difficult to clean effectively, or there may be an unaesthetic appearance (Figure 11.4.2).\nA screw-retained restoration will have a screw-access hole, which disrupts the structural continuity of porcelain, leaving some unsupported porcelain at the hole. Cemented restorations are one piece without any weakening of the structure of the crown. However, it should be noted that if veneering porcelain chips or fractures off an implant restoration in a screw-retained restoration, it would be a relatively simple procedure to remove and carry out an indirect repair on the implant restoration.", "pred_label": "__label__POS", "pred_score_pos": 0.9023296236991882}
{"content": "Eric Wilson’s work poses crucial challenges to social theory, unsettling our understanding of the nature of the liberal democratic state. In\nThe Spectacle of the False Flag, he urges the reader to examine the, often unconsidered, deep state practices that confound conventional notions of the state as monolithic or uniform. This compelling volume traces deep state conflicts and convergences through central cases in the development of American political economic power — JFK/Dallas, LBJ/Gulf of Tonkin, and Nixon/Watergate.\nRigorously documented and unflinchingly analyzed,\nThe Spectacle of the False Flag provides a stunning example of a new criminological practice—one that takes the state seriously, making the inner workings of the state rather than its effects the primary object of study. Drawing upon a wealth of historical records and developing the theoretical insights of Guy Debord’s writings on spectacular society, Wilson offers a glimpse into a necessary criminology to come.", "pred_label": "__label__POS", "pred_score_pos": 0.9498031139373779}
{"content": "Abstract\nThis report features information garnered from OES members. Specifically, this refers to the countries of Canada, China, Denmark, France, Germany, Ireland, Korea, Mexico, Monaco, Nigeria, Norway, Portugal, South Africa, Spain, Sweden, the United Kingdom and the United States of America giving the following report a wide geographic dimension.\nThe progress of ocean energy projects in all the OES member countries continues to face challenges in relation to consenting processes. This can be detrimental to the sector and may also lead to delays in realising operational projects with consequences for budgeting and real costs to developers.\nParticular emphasis has been placed on investigating the main barriers associated with permitting and licensing with a view to advising regulators and decision-makers on the key needs of the ocean energy sector from consenting processes. Developers were also given the opportunity to provide their views and insights on barriers as experienced by them in consenting of their ocean energy projects to date.", "pred_label": "__label__POS", "pred_score_pos": 0.8883777856826782}
{"content": "We investigated the relationship among gender of resident, staff social interaction, and agitation in 46 (31 male and 15 female) nursing home residents with clinically significant agitation. Direct observations were conducted of resident behaviors and environmental contextual events using a computer-assisted, real-time observational system. The system recored frequency, duration, and temporal sequencing of events. Results show that female residents displayed almost three times the amount of agitation as male residents (35% vs. 13% of total observation time, respectively), although men in the study were more likely to receive psychoactive drugs for their agitation. Staff spent similar amounts of time verbally interacting and touching male and female residents. Sequential analyses were conducted to examine the likelihood of staff verbal and touch interactions both preceding and following resident agitation using Bakeman and Quera's (1995) SDIS-GSEQ program. Results suggest that staff touch and verbal interaction elicit agitation in a significant proportion of residents. Once agitation occurs, staff were likely to respond by interacting verbally, but not physically, with the resident.", "pred_label": "__label__POS", "pred_score_pos": 0.6627957820892334}
{"content": "Cyberattacks aimed at profiting from the coronavirus pandemic are expected to intensify with millions self-isolating at home and relying on digital solutions to work remotely, the pan-European policing agency says.\nIn a new report, \"Pandemic Profiteering: How Criminals Exploit the COVID-19 Crisis,\" Europol calls the spread of the coronavirus a cybersecurity risk in which hackers are abusing the demand for supplies and information.\n\"There is a long list of cyber-attacks against organizations and individuals, including phishing campaigns that distribute malware via malicious links and attachments, and execute malware and ransomware attacks that aim to profit from the global health concern,\" it said.\n\"The number of cyber-attacks is significant and expected to increase further. Cybercriminals will continue to innovate in the deployment of various malware and ransomware packages themed around the COVID-19 pandemic. They may expand their activities to include other types of online attacks.\"\nEuropol also noted that the possibility of a cyberattack dealing a major blow an entire sector or society is no longer unthinkable. Thus, in 2018 the European Union adopted an emergency response protocol to facilitate rapid assessment of cross-border cyberattacks as well as sharing of critical information and coordination of international aspects of investigations, the agency said.\nIn a press release, Europol’s Executive Director Catherine De Bolle was quoted as saying, \"While many people are committed to fighting this crisis and helping victims, there are also criminals who have been quick to seize the opportunities to exploit the crisis.\"\n\"This is unacceptable: such criminal activities during a public health crisis are particularly threatening and can carry real risks to human lives. That is why it is relevant more than ever to reinforce the fight against crime.\"", "pred_label": "__label__POS", "pred_score_pos": 0.8496283292770386}
{"content": "The term “personal injury” involves any incident or action that leads to a person or group of people being harmed. Auto accidents, slip and falls, workers’ compensation, wrongful death, medical malpractice, and birth injuries are all examples of potential personal injury cases. Our personal injury lawyers are skilled and knowledgeable individuals who focus on helping injured victims obtain the compensation they deserve for injuries and emotional pain.", "pred_label": "__label__POS", "pred_score_pos": 0.9928663969039917}
{"content": "Museum Station is an underground rail station on Sydney’s City Circle line. The station was constructed in the 1920s using cut and cover techniques. The station has a reinforced concrete arch spanning over two platforms and is linked to ground level by a network of unreinforced concrete tunnels.\nAs part of the state government’s Easy Access Upgrade projects, it is necessary to install a series of lifts to provide access from ground level to the platforms. The heritage listed station is located below Hyde Park and adjacent to the Anzac memorial, and hence the impact of construction on the public and the heritage significance of the area had to be carefully considered.\nRobert Bird Group conducted a review of the reference design and identified significant risks to the existing station. Subsequently RBG was engaged to redesign the concept for the platform lifts, delivering a scheme that provided improved access and circulation.\nSectors: Rail RBG Client: Transport for NSW Primary Contractor: Arenco-Daracon JV Architect: DesignInc Robert Bird Group Services: Civil Engineering Structural Engineering Visualisation (Concept Phase) Construction Engineering\nKey technical challenges\nThe primary tower structure consists of a composite slab and beam structure. Due to the long beam spans and thin slab, extensive analysis for footfall vibration was required to ensure the structure achieved code requirements and client expectations. Working with the existing structure and developing design solutions that strengthened rather than demolished. Extensive co-ordination with the mechanical engineer to develop a strategy that minimised beam penetrations and beam notches. Differential shortening analysis with consideration of mega truss, steel structure, concrete structure and existing structural elements\nEnvironmental performance\n5 Star Greenstar 5 Star NABERs Energy and 4 Star NABERs Water ratings.", "pred_label": "__label__POS", "pred_score_pos": 0.556222677230835}
{"content": "A scheme of state aid to support the transfer of German freight transport from road- to rail-based routes has been approved by the EC.\nThe scheme will support rail freight operators to take over management of German freight transport. This is one of the initiatives intended to reduce road congestion and carbon emissions across the EU.\nUnder the freight transport transference scheme in Germany, rail freight operators will be reimbursed by up to 45 per cent of their track access charges. German rail operators must pay these charges to access the rail network infrastructure. Operators who received the funding will be expected to pass on the savings to their freight shipping customers through lower freight rates. They will be obliged to inform clients of their reduced track access charges.", "pred_label": "__label__POS", "pred_score_pos": 0.9763593673706055}
{"content": "There is something about interacting online that makes it very easy for many people to cross a line and engage in uncivil, hostile, toxic social exchanges that have serious real-world consequences for themselves and others --- consequences such as anxiety, depression, targeting, drama, bullying, verbal and physical altercations, and attempts at suicide.\nIn this teacher seminar --- which we presented at the Ohio Educational Technology Conference, at schools, and as a keynote address at sessions --\nwe provide a framework for understanding the problems social media causes kids, and how schools can work with parents to mitigate them.\nTopics covered include the types of conflict that occur on social media, unique characteristics of interacting online that make us vulnerable to such conflictsocial psychological factors that facilitate social media conflict, psychological states generated by social media conflict, what our research reveals about how burdened kids feel by social media, factors that limit the ability of schools and parents to intervene.\nA digital detox is a period of consecutive days with little-to-no access to digital devices, apps, or content. The more than 7 research studies Mr. Mercier has conducted with 11 to 22-year-olds finds digital detoxes to be enormously beneficial, and for some students, transformational.\nIn this seminar, which was presented at the 2020 Ohio Educational Technology Conference, Mr. Mercier\nprovides an overview of his research on digital detoxes, identifies the stages of a digital detox, explains the process of taking a digital detox, explains how to plan a digital detox for optimal benefit, describes the healing benefits of a digital detox, and suggests ways schools can help students gain access to digital detox experiences.\nTech addiction among adults is a rampant problem that bleeds into work. Screen Education's 3 national surveys workforce research has found that US employees indicate they use their phones during work hours --- for personal reasons --- for approximately 2 hours each day, with 75% reporting that social media is their main distraction.\nThis not only reduces organizational productivity, it also increases the risk of accidents that cause injury, death, and property destruction, and it degrades the work environment by causing frustration, tension, and conflict.\nSchools that wish to help prepare students for their future work lives would do well to begin now to teach them how to self-limit their recreational phone use in situations where such use is inappropriate.\nIn this session we will lay out our astounding findings on tech addiction at wor, discuss how adults have the same sproblesm as kids, and how schools can use this to motivate change.\nThis seminar provides teachers with a framework for understanding digital addiction at a deeper level, and for helping their students overcome it.\nWe have presented this seminar at the Ohio Educational Technology Conference, the Wisconsin Educational Media & Technology Conference, Hiram College, Education Service Center meetings, district-level in-service teacher training days, and at schools.", "pred_label": "__label__POS", "pred_score_pos": 0.5375298261642456}
{"content": "The battle for Yellowstone: Morality and the sacred roots of environmental conflict, by Justin Farrell Abstract\nA growing number of intractable environmental conflicts involving interest groups with deeply held beliefs are resisting resolution in spite of extensive scientific analysis and legal and bureaucratic attention. Justin Farrell addresses three such conflicts in the Greater Yellowstone Ecosystem (GYE) as moral and spiritual conflicts, each uniquely animated by history, context, and social relationships. Drawing on a wide range of methods, ranging from ethnography to computational content analysis, and carefully rooted in place-based experiences and historical processes, this book illustrates the central role of moral orders and commitments in driving conflict, describes how moral environmental beliefs and narratives interact with scientific and technical information, and shows how different actors and contextual factors can drive both polarization and collaboration even at the same place and time. Farrell helps us understand conflict in the GYE and, more significantly, presents a deep and innovative sociological analysis that can inform and expand the theoretical approaches and methodological tool kits that we use to analyze a wide range of environmental issues and conflicts.", "pred_label": "__label__POS", "pred_score_pos": 0.8290826678276062}
{"content": "Document Type\nArticle\nPublication Date\nSummer 8-2017\nAbstract\nThe Society for Standards Professionals (SES) has a significant history of documenting the use of standards in research and academia. For instance, during the 62nd Annual SES Conference in 2013 in Savannah, Georgia, the author participated in such a session highlighting examples of relationships between academic institutions, government, and standards developing organizations. In this article, we attempt to capture the current advances made from similar relationships specific to our home institution, the City College of New York (CCNY) of the City University of New York (CUNY.) These advances have become possible through a grant issued under the Standards Services Curricula Development Cooperative Agreement Program of the National Institute of Standards and Technology (NIST).", "pred_label": "__label__POS", "pred_score_pos": 0.6074110269546509}
{"content": "As the coronavirus (COVID-19) epidemic continues to outbreak across the globe, the Centers for Disease Control & Prevention (CDC) has been regularly releasing new updates and developments, along with best practices and instructions for businesses to help prevent the further spread of the disease. Please note that these may change as international health groups like the World Health Organization (WHO) continue to monitor the virus’ progress. Always refer to the CDC’s website for the latest developments.", "pred_label": "__label__POS", "pred_score_pos": 0.922150731086731}
{"content": "NCASE Resource Library Featured Resources\nThis publication features some of the best resources, including webinars, briefs, and toolkits, available in the online NCASE Resource Library, developed for both practitioners and system builders.\nThese selected resources, curated by NCASE, offer ideas and information for OST system leaders to support recovery from COVID-19.\nThe NCASE Out-of-School Time Professional Development System-Building Toolkit was designed to assist states as they build professional development systems inclusive of school-age providers.\nSearch for Resources ? Search Results Filter By Reset Selections Expand All Filters Topics Resource type Publisher Search Results Filter By\nThis report offers recommendations to build a workforce that is unified by the foundation of the science of child development and early learning and the shared knowledge and competencies that are needed to provide consistent, high-quality support for the development and early learning of children from birth through age 8.\nThis report is the third edition that investigates how the early childhood education (ECE) field is cultivating leaders within the field. Based on a survey, it examines the role of 57 self-identified leadership development programs in supporting staff learning of leadership skills.\nThis video by novelist Chimamanda Adichie shares a powerful message that when we hear only a single story about another person or country, we risk a critical misunderstanding. She shares examples of how a single story can paint an incomplete picture and can rob people of their humanity.\nThis video provides a unique overview of the important role afterschool has played in American history, beginning in the 1880's with the age of industrialization. It is broken into 12 brief chapters that captures the social upheaval of the late 1800's, then the growing need for supervision into the 1900's, and the rapid growth over the past 50 years.\nThis journal article documents one OST director’s journey through the process of becoming credentialed. It explores fears and challenges and what she—and her program participants, families, and staff—ultimately gained from the process. This story can bring a personal experience to life for state system planners creating or supporting a school-age credential.\nThis article explores the challenges and potential of school-afterschool partnerships. Based on interviews with school administrators, afterschool leaders, and front-line staff in three schools, the findings reveal both disconnections and opportunities for fuller communication and collaboration.\nThis resource guide is designed to help community-based organizations (CBOs) understand and develop cultural competency—the ability to work effectively in cross-cultural situations. It offers a framework for understanding cultural competency, including sections such as: choosing interventions, conducting a needs assessment, workforce diversity, budgeting and costs for intervention.\nThis report highlights the importance of healthy, supportive relationships to positive youth outcomes.\nThis video on social-emotional learning (SEL) examines core capabilities known as executive function and self-regulation skills. It explores what these skills are, why they are important, how they develop, and how they are negatively affected by stress for children, adolescents, and adult caregivers. This resource supports resilience.\nThis quality outcomes study of a summer program in Seattle Public Schools provides evaluative evidence for an instructional model that showed positive change in academic performance and high quality instructional practices.", "pred_label": "__label__POS", "pred_score_pos": 0.9356766939163208}
{"content": "Returnships might fill your talent gap\n$225.00\nDescription\nAbstract: In today’s tight job market, employers must innovate when it comes to filling their positions. Returnship programs can provide welcome and valuable relief for nonprofits facing hiring challenges. This article explains how returnships work, and the benefits and risks they offer.", "pred_label": "__label__POS", "pred_score_pos": 0.5743677020072937}
{"content": "How to Obtain a Clothing Store License\nCompared to drawing up a business plan, securing funding, finding premises and sourcing staff, the process of applying for the licenses you'll need to open a clothes store is relatively straightforward. In most areas, it's merely a case of filling in some application forms and waiting for your licenses to arrive. In some states and counties, it's even simpler than that.\n1\nNavigate to the Internal Revenue Service website and apply for an Employer Identification Number. You’ll need an EIN if you plan to employ people, are in a partnership or plan to trade as a corporation.\n2\nContact your local licensing authority to inquire about the licenses you'll need to start trading. Although requirements will vary depending on the state and county you're setting up in, you'll usually need a seller's license or a resale certificate as a minimum. You may need a range of additional licenses such as a health license, a building permit or an alarm permit depending on your locality. You'll need a specific license to sell secondhand clothing in some states. You can use the Small Business Administration's website to find information on specific licensing requirements in your area.\n3\nRequest application information for the licenses you'll need from your local licensing authority. Then, complete each application form and return it along with any supporting documentation requested and a check for any fees and charges if necessary. You may be required to submit to an inspection before certain licenses are granted.\n4\nContact your local Department of Revenue to register for sales tax and apply for a sales tax license or certificate if necessary in your area.\nReferences\nResources\nWriter Bio\nMichael Roennevig has been a journalist since 2003. He has written on politics, the arts, travel and society for publications such as \"The Big Issue\" and \"Which?\" Roennevig holds a Bachelor of Arts in journalism from the Surrey Institute and a postgraduate diploma from the National Council for the Training of Journalists at City College, Brighton.", "pred_label": "__label__POS", "pred_score_pos": 0.7757542729377747}
{"content": "Abstract\nPatients with advanced-stage colon cancer often exhibit resistance against treatment and distant metastasis, both key contributors to poor prognosis. Emerging evidence indicates that cancer stem cells (CSCs), characterized by the enhanced ability to self-renew, resist therapeutics, and promote metastasis, represents a clinical challenge to target. Alternative therapeutic approaches are urgently required. Here, we explored the feasibility of disrupting the intracellular communications between CSCs and the tumor microenvironment by way of exosomes. First, we demonstrated that exosomes secreted by colon tumorspheres (Exosp) promoted 5-FU resistance, migration, and tumorsphere formation. Exosp also increased the generation of cancer-associated fibroblasts and M2 polarized macrophages in vitro. Oncogenic molecules, including IL-6, p-STAT3, TGF-β1, and β-catenin, were identified as the cargoes of Exosp. Furthermore, the public database revealed the high abundance of miR-1246 in serum exosomes from colon cancer patients, and we verified in the Exosp from HCT116 and HT29 cells. Therapeutically, we demonstrated the ovatodiolide treatment reduced exosomal cargoes from tumorspheres (Exosp_OV). Exosp_OV were significantly less capable of promoting 5-FU resistance, migration, and tumorsphere formation when co-cultured with HCT116 and HT29 cells. Notably, Exosp_OV was less CAF- and M2 TAM-transformative. Computational docking analysis revealed that OV could bind and significantly reduced β-catenin activity. Finally, mouse xenograft data indicated that ovatodiolide suppressed tumor growth via down-regulating IL-6, STAT3, β-catenin expression, and serum exosomal miR-1246. In conclusion, our findings provided preclinical supports for ovatodiolide as a colon CSC inhibitor by reducing β-catenin/STAT3/miR-1246 signaling conveyed by CSC derived exosomes.\nOriginal language English Pages (from-to) 2337-2354 Number of pages 18 Journal American Journal of Cancer Research Volume 10 Issue number 8 Publication status Published - 2020", "pred_label": "__label__POS", "pred_score_pos": 0.9858126640319824}
{"content": "Abstract\nBACKGROUND: We previously developed substitutes for red blood cells (RBCs) and platelets (PLTs) for transfusion. These substitutes included hemoglobin vesicles (HbVs) and fibrinogen γ-chain (dodecapeptide HHLGGAKQAGDV, H12)–coated, adenosine diphosphate (ADP)-encapsulated liposomes [H12-(ADP)-liposomes]. Here, we examined the efficacy of combination therapy using these substitutes instead of RBC and PLT transfusion in a rabbit model with trauma-induced massive hemorrhage with coagulopathy. STUDY DESIGN AND METHODS: Thrombocytopenia (PLT count approximately 40,000/μL) was induced in rabbits by repeated blood withdrawal and isovolemic transfusion with autologous RBCs. Thereafter, lethal hemorrhage was induced in rabbits by noncompressible penetrating liver injury. Subsequently, H12-(ADP)-liposomes with platelet-poor plasma (PPP), platelet-rich plasma (PRP), or PPP alone were administered to stop bleeding. Once achieving hemostasis, HbVs, allogenic RBCs, or 5% albumin were transfused into rabbits to rescue them from fatal anemia following massive hemorrhage. RESULTS: Administration of H12-(ADP)-liposomes/PPP as well as PRP (but not PPP) effectively stopped liver bleeding (100% hemostasis). The subsequent administration with HbVs as well as RBCs after hemostasis markedly rescued rabbits from fatal anemia (75% and 70% survivals for 24 hr, respectively). In contrast, 5% albumin administration rescued none of the rabbits. CONCLUSION: Combination therapy with H12-(ADP)-liposomes and HbVs may be effective for damage control resuscitation of trauma-induced massive hemorrhage.\nASJC Scopus subject areas Immunology and Allergy Immunology Hematology", "pred_label": "__label__POS", "pred_score_pos": 0.770582914352417}
{"content": "This bill would finally increase pay and workforce protections for Transportation Security Officers, who are among the lowest-paid federal employees, in addition to addressing the chronically low morale and high turnover at the Transportation Security Administration.\nIt may be well-intended, but this bill would undermine the TSA’s national security mission by preventing the agency from addressing instances of serious misconduct, such as knowingly allowing a weapon to pass through security, through one-step removal.", "pred_label": "__label__POS", "pred_score_pos": 0.8388246893882751}
{"content": "The evolution toward stronger analytics has laid the groundwork for artificial intelligence, which uses sophisticated algorithms to produce smarter insights from traditional data.\nAs new AI technologies hit the market, it can be difficult for financial institutions to know where to begin. In considering the path forward, two elements of AI merit close attention: natural-language processing and machine learning.", "pred_label": "__label__POS", "pred_score_pos": 0.6024199724197388}
{"content": "Every Business Associate (BA) that\ncreates, receives, maintains, or transmits protected health information (PHI) is to perform a comprehensive organization-wide HIPAA Risk Analysis (Per: §164.308(a)(1)(ii)(A)). required\nThis includes establishing and maintaining effective Security Management Process is not only a requirement, but is also a\ncritical and a necessary activity for the protection of ALL of your patient’s PHI.\nToday, we focus on HIPAA Security Risk Analysis from three distinct areas. They are:\nBusiness Risks determine your level of risk tolerance and the likelihood of occurrence. Patients Safety securing the PHI is patient care. Errors could occur including risk to patient care from lost or changed data, or a harmful drug interaction. Adhere to regulatory compliance.\nEach of these areas may have a higher risk level to different individuals. However, each organization must evaluate\npossible risk areas and its effect in their environment. ALL Covered Entities and Business Associates need to understand patients are entrusting them with their most private and intimate details, they expect it to remain . secure\nBesides, it is\npractice, YOUR patient’s, YOUR reputation and YOUR legacy! Why are you leaving yourself wide open to such risks? YOUR\nDon’t know\nwhere or how to start or update your HIPAA security compliance training? Let’s chat about your compliance program – schedule a call with HIPAA alli today!", "pred_label": "__label__POS", "pred_score_pos": 0.9611824750900269}
{"content": "This chapter begins by outlining the routes through which children ‘drop out’ of school. It then draws on the failings of the English system to suggest six key ‘lessons’ for other jurisdictions. The first centres on how academic results-driven accountability measures push schools and decision-makers into unjustifiably excluding children. The second demonstrates the vulnerability of discretionary frameworks to perverse incentives and unintended negative consequences for children at risk of ‘drop out’. The third highlights the difficulties created by increased autonomy for teachers and schools. The fourth reveals how additional protections for particularly vulnerable children are constrained by the broader exclusion regime. The fifth and sixth demonstrate the need for jurisdictions to revisit the conceptual and empirical basis of their legal frameworks for exclusion, whether grounded in ‘best interests’, competing ‘interests’, or ‘children’s rights’. It concludes by emphasising the need to develop empirical evidence to underpin decisions around ‘drop out’.\n[A pre-publication version of this chapter is available here. It will be published in JG Dwyer (ed), Oxford Handbook of Children and the Law (OUP 2019).]", "pred_label": "__label__POS", "pred_score_pos": 0.9991342425346375}
{"content": "Below is your weekly dose of wellbeing, curated from trusted news sources.\nBalancing Virtual and In-Person Health Care Harvard Business Review\nThe shift to virtual care during the COVID-19 pandemic has sparked endless questions such as: How much virtual care makes sense when we return to a new normal state? What is the best approach to offering virtual care alongside in-person care? How will we know whether virtual care is succeeding?\nHow Might A Pandemic Change Gen Z’s Approach To Benefits? Employee Benefit News\nGenerations are shaped by their experiences, and Gen Z will be no different. The pandemic has shifted a lot of this generation’s expectations and engagement with employee benefits specifically.\nMcKinsey Report: 62% Of Workers Worldwide Consider Mental Health ‘A Top Challenge’ CNBC\nIn a new global survey, McKinsey found that while 96% of companies globally have made changes to their HR policies and increased employee resources, only 1 in 6 employees report feeling supported and 62% of employees globally “consider mental health issues a top challenge.”", "pred_label": "__label__POS", "pred_score_pos": 0.5193040370941162}
{"content": "Historically, divisions have existed in the field of Intimate Partner Violence, with intense and sometimes acerbic debate ensuing in the literature between scholars affiliated with a \"feminist\" perspective and those affiliated with a \"family conflict\" perspective. New scholars just entering the field lack a historical understanding of how these divisions came to be, what are the core questions at the heart of the divide and how have leaders in the field navigated these questions along their own professional journeys? This dissertation is an effort to document from a first person perspective an extensive review of the scholarly literature related to these divisions and a narrative inquiry and analysis of how six leading scholars in the field, affiliated with both perspectives describe their journey.", "pred_label": "__label__POS", "pred_score_pos": 0.9611437916755676}
{"content": "I'm currently studying secret key cryptography, and I've come across the terms \"long-term key\" and \"session key\".\nWhat's the difference between these two kinds of keys?\nCryptography Stack Exchange is a question and answer site for software developers, mathematicians and others interested in cryptography. It only takes a minute to sign up.Sign up to join this community\nFirst, understand that keys need to last only as long as you need to recover what they are protecting. If you are storing a secret in a box until next year, you have to keep the key until next year. But if we're talking on the phone, we only have to keep the key for the duration of the phone call.\nIf Alice and Bob are going to speak securely, they don't need to keep the shared secret key around for a long time. They only need it for as long as they're speaking. And they don't want someone who records their conversation to be able to learn what they said. If they agree on a temporary key, one that lasts only as long as their conversation, that is a session key.\nA session key is one that is not intentionally stored, and is not re-creatable. Session keys are used only for communications protocols, never for storage purposes. In computer protocols like SSL, the session key is generated randomly, exchanged securely with the other computer (using a key exchange protocol like DH), and remains in each computer's memory only for the duration it is needed (a session.) When the session is ended, both sides wipe their copies of the key from memory.*\nA long-term key is one that is deliberately stored somewhere, either on a computer disk, flash memory, or even printed on paper. The key is intended to be used at multiple points in time, such as \"I will use this key to encrypt this secret file today, and use it again to decrypt my secret next week.\" A long term key can be used for any purpose, including stored information as well as transient communications.\n* Note that an attacker can certainly record the session key exchange, and if they can break the key exchange cryptography they can decrypt the session key.", "pred_label": "__label__POS", "pred_score_pos": 0.8504835963249207}
{"content": "The new bridge across Oregon Inlet has already garnered acclaim from travelers since first opening in February of 2019, but thanks to a recent announcement from the Deep Foundations Institute (DFI), it can add an international award to its wave of accolades as well.\nThe DFI has recognized the new Marc Basnight Bridge as the winner of its the 2019 DFI Outstanding Project Award, honoring both PCL Civil Constructors (general and foundation contractor) and North Carolina Department of Transportation (owner) for the innovative foundation design of the 2.8 mile-long structure.\nThe Deep Foundations Institute (DFI) is an international membership association of contractors, engineers and suppliers in the field of design and construction of deep foundations and excavations. Their Outstanding Project Award (OPA) was established in 1997 to recognize the superior work of DFI members, and each year, a project is chosen from several geotechnical projects submitted for consideration by DFI members.\nThe eventual winner is selected by a committee which takes a number of factors into account, including the project’s size, the scope and challenges of the project, the degree of innovation and ingenuity exercised, and the uniqueness of finding a solution to the difficulties of the job.\n“The new bridge replaces the Herbert C. Bonner Bridge and was built using first-of-their-kind design and construction methods to provide a 100-year service life, resist unprecedented scour depths and minimize environmental impacts while offering a reliable, safe passageway to and from Hatteras Island,” stated the DFI in a press release.\n“The bridge is capable of resisting wind, wave and vessel collision forces from the worst storms in the Atlantic Ocean, all while subject to unprecedented scour depths.”\nThe announcement also praised the project for its foundation design, noting that the design was a key factor to the project’s success, but also posed the greatest challenges. “Driven, pre-stressed concrete piles were selected for the long spans as well as the approach and transition spans, and provided the required strength and durability. To address the concern of how to drive large displacement piles through dense sand, the team developed innovative jetting installation methods. The need to optimize the design led to the extensive use of refined soil-structure interaction analyses.”\nThe award is being presented at the DFI 44th Annual Conference on Deep Foundations in Chicago, October 15-18, 2019.", "pred_label": "__label__POS", "pred_score_pos": 0.515005886554718}
{"content": "Today I chose to venture into London for a relaxing massage and rolfing appointments. In the past, my journey was quite simple: tube from Essex to London. But since I have moved house, it’s more complicated. Do I choose to drive one hour away to my old home, park, and then take the hour tube ride? Or do I opt for the two hour costly train ride, with a transfer.\nSince I was going for the relaxation and pamper effect today, I opted for the train. I was paying for the luxury of the train, I could write and read while having loads of space as I ventured into the city. But as I got on board the second train, I wondered if I made the wrong decision. The coaches were extremely packed with people. It was standing room only. I questioned if this was the right decision, or if I should have even gone to London today. Despite this, I would make the most of it. I continued to read silently.\nLuck entered my life, a woman next to me was getting off at the upcoming Cambridge stop. She offered me her seat. I gladly took it, and was filled with gratitude. She didn’t have to mention it to me. Me and the fellow passengers would have fought like vultures for her space. But I didn’t have to fight. A spot was made available for me, and I accepted. It’s interesting the smallest act of kindness can bring such joy into our lives.\nI appreciated having somewhere to sit and a tiny bit of personal space, on the remaining hour long train ride. It’s so often we take things for granted, but one act of warmth by a stranger can deeply impact the rest of our day. In return, I offered her a gratitude card.\nI listened on the train as somehow laughter emerged throughout the tight journey. People could easily react with frustration for having to stand during an expensive long train ride, next to strangers, with little room to move. The overcrowded train ride was unexpected for everyone, but somehow overall people’s spirits remained light. Two more people were getting off the train, a nearby passenger voiced this aloud to the crowd. He wasn’t going to take the seat, but it was available for anyone who needed it. People joked of their competitiveness of wanting these seats, but nobody ran for them. Everyone seemed to enjoy the journey as much as they could. It was Saturday after all. Why not embrace the moment for what it is?\nWhen we arrived at Kings Cross, someone shouted, “have a good day everyone.” The crowd cheered. Several others yelled have a good day. And then we were all off on our own separate ways.\nIt may be normal to send out to the world negative internal vibes of frustration, particularly during moments of traffic or rush hour during the week. One can generally sense hurriedness, excess hyped up energy, and pushiness. Yet in this same manner, we can send out blessings to fellow passengers on our journeys. We can make the most of right now.\nPerhaps it’s simply a Saturday vibe mentality, which is not too far off that vacation state of mind. Since we are free from work responsibilities and expectations, we can let loose, slow down, and find joy. I appreciate everyone who rode on the train with me today for making it a pleasant and memorable journey. Kindness and warmth is truly contagious…", "pred_label": "__label__POS", "pred_score_pos": 0.5029832124710083}
{"content": "Abstract\nA comprehensive technical feasibility study was conducted of a bioethanol demonstration plant with the aim of converting parts of an existing fuel-grade bioethanol production into a more valuable solvent-grade ethanol. The study focuses on the separation unit, which consists of three consecutive distillation columns and a dehydration step using molecular sieves. This separation unit did not permit sufficient removal of crotonaldehyde and methanol for obtaining solvent-grade ethanol. Therefore, an additional distillation column after the dehydration step was investigated by simulation. It is operated at subatmospheric pressure and enables simultaneous removal of methanol, crotonaldehyde, and water in the distillate. The distillate meets the fuel-grade ethanol specifications, while the bottom product meets the solvent-grade specifications. It enables around 70% solvent-grade ethanol production and employs a vacuum pump that is already used in the considered plant. A stationary operating point is characterized by online operational data and experimental results of liquid samples. Particular emphasis during the characterization is put on trace compounds. Ethanol and the following 13 trace compounds were analyzed experimentally: Acetaldehyde, 1-propanal, 1-butanal, crotonaldehyde, benzaldehyde, ethyl acetate, methanol, 1-propanol, 1-butanol, 2-butanol, 2-methyl-l-propanol, 2-methyl-l-butanol, and 3-methyl-1-butanol. A simulation platform was established and evaluated with excellent agreement compared to the operational data. The beer composition (separation unit feed) and a complete stream summary for the separation unit is provided.", "pred_label": "__label__POS", "pred_score_pos": 0.9962869882583618}
{"content": "Activities per year\nAbstract\nThrough a case study based in Bristol, this article explores how the 'law of place' has transformed multiple heterogeneous city centre spaces into a single homogeneous and commodified privately owned retail site. Drawing on de Certeau, Lefebvre, and humanistic geographers including Tuan, the article explores how law facilitates spatial and temporal enclosure through conventional understandings of private property, relying on techniques of masterplanning, compulsory purchase, and stopping up highways. It suggests that the law of place draws on binary spatial and conceptual distinctions to apparently separate places from spaces, applying different legal rules either side of an often invisible boundary line. The article questions this legally facilitated spatial and conceptual enclosure, particularly as it restricts spatial practices within the public realm. It concludes by rejecting an urban 'right to roam' as insufficiently transformative, calling for a broader interpretation of Lefebvre's 'right to the city' instead.\nAntonia Layard (Invited speaker)31 Mar 2014\nActivity: Participating in or organising an event types › Participation in conference", "pred_label": "__label__POS", "pred_score_pos": 0.7814039587974548}
{"content": "While still adjusting to retirement, I was watching the 2016 Summer Olympics one recent evening when I was struck by a television ad. It was selling audible books, not just for adults, but also [...]\nAs I prepare to retire at the end of this month, I wish to share some reflections and concerns which arose from my reading of a rather profound book, Reclaiming Conversation: The Power of Talk in [...]\nResearch into the complex nerve connections of the developing brain has exploded in the last 20 years, and one conclusion is clear: From Day 1, every day counts. We know that children who from [...]\nIntroducing KidsDoc Symptom Checker, the best phone app a concerned parent may ever buy. Innumerable are the anxious moments the average parent has spent agonizing over what to do next for their [...]", "pred_label": "__label__POS", "pred_score_pos": 0.588337779045105}
{"content": "The Accessible Information Standard aims to ensure that disabled people have access to information they can understand and the communication support they may need. The Standard applies to service providers across the NHS and adult social care system.\nIndividuals most likely to be affected by the Standard include people who are blind or deaf, who have some hearing and / or\nvisual loss, and people with a learning disability. However, this list is not exhaustive.\nIf you have any specific Information or Communication needs, then please let us know. Reception will be happy to help you, so this information will be added to your medical records to assist us in supporting your needs.", "pred_label": "__label__POS", "pred_score_pos": 0.9667006134986877}
{"content": "Plantain varieties have been identified as having positive effects on production and reducing nitrate leaching risk. These include increases in milk production, diuretic effects on the animals and the effects of bioactive compounds on soil processes.\nOverseerFM reflects the current knowledge of the effects of Ceres Tonic’s plant composition on urine nitrogen excretion, as found in extensive research with this variety: a lower apportioning of the excreted nitrogen to urine and a lower nitrogen load per urine patch due to a greater urine volume per animal per day.\nAny effects relating to greater milk production would be reflected by user input of milk volume.\nAt present, OverseerFM does not reflect the potential effects of plantain’s bioactive compounds on soil processes.\nFurther research is planned to better understand these effects on nitrogen processes in the soil, such as nitrification. Results from this research will inform potential further updates of OverseerFM. Additionally, DairyNZ have confirmed that this research will aim to provide a framework to assess the chemical profiles of other plant varieties to verify that they possess the attributes that result in N leaching reductions.", "pred_label": "__label__POS", "pred_score_pos": 0.9874016642570496}
{"content": "Fifth edition Handbook by DLA Piper’s Data Protection and Privacy practice: “More than ever it is crucial that organisations manage and safeguard personal information and address their risks and legal responsibilities in relation to processing personal data, to address the growing thicket of applicable data protection legislation.\nA well‑constructed and comprehensive compliance program can solve these competing interests and is an important risk‑management tool.\nThis handbook sets out an overview of the key privacy and data protection laws and regulations across nearly 100 different jurisdictions and offers a primer to businesses as they consider this complex and increasingly important area of compliance….(More)”", "pred_label": "__label__POS", "pred_score_pos": 0.5229796171188354}
{"content": "In the growing unrest in Hong Kong, you may be considering moving to Australia – you should be aware of the following tax issues:\nIf you have monies in a pension fund, you can rollover these funds into an Australian superannuation fund provided you do this as soon as you become a resident of Australia.\nIf you become an Australian resident, dividends and rental income received from foreign investments are subject to tax in Australia when a dividend is received.\nYou will also be subject to capital gains tax (CGT) when you sell any offshore asset. The amount of the capital gain is the difference between the value of the asset at the time you become a resident of Australia and the time at which you sell the asset.\nIf you own a residential property offshore, you will need to have the property valued when you become a resident of Australia, and this price will then become a guide for the tax you will pay when you sell the property.\nIf you rent the property offshore when you become a resident then all the rent, minus expenses, will be fully taxable in Australia.\nAll shares, regardless of whether they are Australian shares, are taxable in Australia when you become a resident.\nSelling an overseas investment portfolio after a non-resident has become a tax resident of Australia triggers significant Capital Gains Tax consequences.\nIf you are unsure about the tax consequences if you move to Australia, contact us now. Waterhouse Lawyers are experts at providing advice on how best to structure your tax affairs.", "pred_label": "__label__POS", "pred_score_pos": 0.8010640740394592}
{"content": "British Gas has made significant changes to its prepayment method since 1\nst January, ending its relationship with PayPoint in favour of rival PayZone as the valid terminal for topping up prepay meters.\nThe partnership with Post Office-owned PayZone means that customers would have 15,000 fewer top-up terminal locations. Several people have criticised the move, but the Post Office is hopeful that the changes can increase footfall to its branches and PayZone outlets.\nPart of the agreement also caused an increase in the minimum top-up amount from £1 to £5. The energy provider has also set £5 as the minimum top-up for other prepay channels, including over the phone, British Gas website and app, and post offices.\nAdditionally, customers are directed to top up to the nearest pound.\nPrepayment meters are a select energy meter type that is typically installed on domestic households. British Gas’s Smart Pay As You Go allows customers to pay for energy before use through topping up a smart key card that inserts to the meter.\nTariffs for prepaid accounts tend to be more expensive than monthly deals.\nPayPoint, the previous to-up partner, has 28,000 terminals in retailers like supermarkets, garages, and newsagents. The old system allowed consumers to pay at 39,500 locations, both from PayPoint and the Post Office’s 11,500 branches.\nHowever, the changeover cuts this number to only 24,500 – since PayZone only has 13,000 terminals across the nation.\nPayPoint has cited the failure to agree renewal terms for the multi-year contract as the reason for their deal ending. In a message to its shareholders, PayPoint revealed that the deal with British Gas only lasted until 31\nst December 2019.\nWith the termination of the partnership, PayPoint expects a £1.4-million loss in revenue for 2019/2020, and another £3.5 million the year after.\nPayPoint CEO Patrick Headon stated that the failure to agree renewal terns for the contract caused disappointment to British Gas and PayPoint customers. He also mentioned that the multi-year partnership was mutually beneficial to both companies.\nPayZone, the new prepayment terminal, has considerably fewer locations. However, British Gas indicated on its website that the outlets are open at extended hours, and some are available seven days a week.\nThis significant change to British Gas causes highs and lows for its PPM customers. On the one hand, clients near PayZone terminals will benefit significantly. However, plenty of households are nearer to a PayPoint outlet, which makes topping-up an inconvenience now that the latter has terminated its partnership with British Gas.\nOne emerging problem is that people with prepaid meters are often vulnerable, which is why they rely on walking or public transport to top up their smart cards.\nIn the Ofgem State of the Market report for March 2019, it is stated that there are 4.3 million consumers using prepayment meters across all energy suppliers. This number is a significant slice of the population that needs to pay before they can use energy.\nCustomers struggling to meet payments are typically shifted to a prepayment meter. British Gas has met criticism along with other suppliers for installing these meters forcibly from 2016 to 2017.\nPrepaying households are shown to pay more for energy than those using traditional meters. A recent adjustment on the price cap moved the average payment to £1,217 a year, an extra cost of £38.\nBritish Gas prepayment members are advised to consider other payment channels to make it more convenient for those who don’t have PayZone outlets or Post Office branches near them. The company encourages its customers to top-up online via the website or mobile app, or over the phone.\nCustomers may also benefit from switching to a standard credit meter, which could mean cheaper energy deals for them and savings of several hundred pounds per year. They can also think about switching from suppliers that use PayPoint terminals, such as Ovo Energy, SSE, nPower, and EDF Energy.", "pred_label": "__label__POS", "pred_score_pos": 0.9844025373458862}
{"content": "Most employer schemes don’t embrace ESG investments For employers and intermediaries only.\nJust one in ten employers believe their pension offering has actively embraced ESG investment options, according to research by Howden Employee Benefits & Wellbeing.\nThe research revealed just over 9% of respondents said their pension scheme is already strongly aligned with ESG requirements, while just 13% said their scheme is taking steps to understand and embrace ESG investments.\nMore than half of respondents (57%) revealed they did not know the current position of their scheme in relation to ESG investments.\nThis comes after regulations came into force in October 2019 which require schemes to set out their policy on financially material investment factors - including ESG considerations - in their statement of investment principles.\nHowden suggested employers should also\"be more aware of ESG pension scheme investments to avoid potential reputational damage\".\nHead of benefits strategy Steve Herbert said,\"The reality is that the UK public is becoming increasingly aware of ESG investment issues.\n\"[It is a subject] that can spark fierce emotions in people. So it follows that we are likely to see many more challenges to pension schemes with regard to investments that are not seen as environmentally or socially acceptable.\"\nHe added,\"Employers need to understand that, regardless of where the legally required investment duties may actually rest, there is an intrinsic and very public link between the sponsoring employer and its pension scheme offering in the minds of members, employees, customers, and the media.\n\"We urge employers to become more involved in, or at least aware of, their pension scheme's investment decisions with ESG guidance in mind.\"", "pred_label": "__label__POS", "pred_score_pos": 0.527630090713501}
{"content": "Like many of the ancient and eroded craters in Mars’ southern highlands, these three craters have flattened rims, shallow floors, and have been filled with sediment in the four billion years since their formation. There is also evidence of ice here – the smallest crater has marks that are typically created as ice and debris creep across a surface, similar to how mixed rock-and-ice glaciers or debris-covered ice glaciers move in alpine regions of Earth.\nThis frame may once have contained other craters, as indicated by the round patches of sunken surface to the top right and bottom left. In fact, despite the cratered nature of Noachis Terra, the environment around this triplet is surprisingly smooth for such ancient terrain. Only a handful of small surrounding craters appear to have clear, sharply defined rims and bowls, indicating that they are relatively young and have not yet begun to erode in earnest. Overall, it seems that older craters in this area have ‘melted down’ into the surface – a phenomenon that is, again, due to ice.\nAs ice just under the surface of Mars flows and melts over many millions of years, the soil becomes softer. This soft, ice-rich soil subsides more quickly and fills up indentations and depressions more readily, contributing to the smooth appearance of this part of Noachis Terra. This suggests that there must have been a large amount of water present on Mars, at least during the Noachian period, capable of producing a glacier-like flow of abundant ice.", "pred_label": "__label__POS", "pred_score_pos": 0.5875508189201355}
{"content": "Earning an MBA is a milestone accomplishment — and one not without its challenges. The majority of students enrolled in an online MBA program will experience stress at some point during their academic experience, but there are ways to minimize it and respond productively.\nThese three tips will help you feel less stressed and more in control as you complete each course in your online degree program.\n1. Designate time for studying and completing your coursework.\nOnline degree programs are known for their flexibility, and they are an ideal option for individuals with professional responsibilities who want to earn a higher-level degree. By creating a schedule with designated study hours, online students can be more consistent and successful. Set aside an hour or two each day, and make sure you stick to your schedule.\n2. Prioritize self-care, and take time out to do things you enjoy.\nWhen working full-time and completing coursework in your online MBA degree program, it might feel like there's no time left in the day for you. Each week, make sure to spend time doing something you truly enjoy. Whether that's exercising at the local gym, taking a yoga class with friends, or reading a book at the park, self-care should be a priority.\n3. Reach out for support if and when you need it.\nWhen you are not taking classes in a physical classroom, it can feel like you are on your own. Recognize that resources are available to you. If you feel stressed or overwhelmed with your current course load, contact an advisor or reach out to your professor. You might even want to connect with other students in the class to discuss how they are managing their responsibilities. It can help significantly to connect with the network of support that’s there for you.", "pred_label": "__label__POS", "pred_score_pos": 0.8365650773048401}
{"content": "Objective: Obstructive sleep apnea (OSA) syndrome is a common disorder that can cause hypercoagulation. Mean platelet volume (MPV) and platelet distribution width (PDW) are associated with hypercoagulability. This study aimed to investigate whether MPV and PDW values change in patients with OSA who were treated with continuous positive airway pressure (CPAP) device.", "pred_label": "__label__POS", "pred_score_pos": 0.9969325065612793}
{"content": "Public companies are required to keep investors and the public well informed concerning their financial condition. People rely on this information and expect it to be accurate. Accordingly, a company must file a restatement if it determines that its previous financial disclosures were inaccurate, and that people should not rely on them.\nThis blog touches on a few data points from an extensive report produced by two of our researchers, Joseph Burke, PhD, and Joseph Yarbrough, PhD. If you want access to the full report, email jcheffers@watchdogresearch.com. The analysis for this report was primarily derived from the Audit Analytics restatement database.\nOne thing to note is that restatements have declined significantly over the past ten years, although the rate of decline has slowed significantly.\nThis graph shows the annual share of companies filing one or more financial restatements from 2010 to 2019.\nThis decline should bring a great deal of comfort to many companies since restatements are one of the most harmful gray swan events that we track. Restatements are often the opening salvo in a torrent of bad press. A restatement often occurs because of a substantial material weakness in the internal controls and often can precipitate turnover in the management team, particularly at the CFO position. Additionally, restatements often trigger class action securities lawsuits.\nOur analysis compared the returns over the thirty days following a restatement to the returns from the S&P 500 over the same timeframe. The data shows that the typical reaction of the market to a restatement is negative (approximately 2/3 of restatements resulted in negative returns). The most common result is negative returns from zero to 10%, but a significant portion (approximately 15%) had a negative return of 20% or more.\nThis graph groups companies by how their share prices performed in comparison with the S&P 500 in the 30 days after a restatement was reported.\nOur analysis indicates that for many companies, issuing a restatement is a trying—but manageable—event. However, in a significant minority of cases, the losses can be catastrophic.\nSome Notable Cases from 2019\nEven though the percentage of companies impacted by a restatement in 2019 was relatively low, some of the restatements that did occur had a near record-breaking impact.\nPareteum Corp (TEUM) had a restatement in October, 2019, and lost 69.6% of its value over the next 30 days ($119 in market cap). TEUM’s decline in value (as a percentage of its pre-restatement value) over the thirty days following its restatement was more than any other company in the last ten years. TEUM was delisted in October 2020. Kraft Heinz (KHC) had a restatement in February 2019 that erased $12.7 billion in market cap after its restatement on February 9th, 2019. This loss in vale was the second largest in the last ten years. If you want to know more, you can read some of our analysis on KHC here, and here, and here. Baxter International Inc (BAX) had a restatement in October 2019 that erased $4.39 billion in market cap over the next thirty days. Even though BAX lost significantly less money than KHC, it was still the third largest loss of value in the last ten years. Conclusion\nRestatements today are far less common than they were a decade ago, although the rate of decline has slowed in recent years. Our research also shows that 2/3 of restatements have a negative impact on share price. Although the response to a restatement is generally negative, people may be surprised by the fact that 1/3 of restatements had\nno negative impact on the share price after 30 days.\nEven though restatements are not as common as they used to be, a restatement can still be a catastrophic gray swan event, as is evident from the negative impact that they had on TEUM, KHC, and BAX in 2019.\nThese restatement numbers are just one facet of our Gray Swan Event Factor. With our GSEF we calculate the risk of gray swan events for over 4,500 publicly traded companies. If you would like a demo, email our President Brian Lawe via blawe@watchdogresearch.com.", "pred_label": "__label__POS", "pred_score_pos": 0.5506861805915833}
{"content": "AbstractClinical tools to guide in the appropriate treatment selection in immunoglobulin light chain (AL) amyloidosis are not well developed. We evaluated the response and outcome for various regimens at first-line treatment (n=681) and first progression (n=240) stratified by the immunoparesis status at diagnosis. Immunoparesis was assessed by the average relative difference of the uninvolved immunoglobulins, classifying patients into a negative average relative difference (i.e. significant immunoparesis) or a positive average relative difference (no/modest immunoparesis). Treatment was categorized as autologous stem cell transplant and four non-transplant regimens (melphalan-based; bortezomib-based, immunomodulatory drug-based and dexamethasone alone). Patients with significant immunoparesis who underwent stem cell transplant had a significantly lower rate of very good partial response or better response (58%), progression-free survival (median 30 months) and overall survival (108 months), compared to those without significant immunoparesis (80%, 127 months, median not reached, respectively; P<0.001 for all comparisons). Among the non-transplant regimens, melphalan resulted in an unfavorable progression-free survival (11 vs.27 months; P<0.001) and overall survival (30 vs.74 months; P=0.001) in patients with significant immunoparesis compared to those without significant immunoparesis. In contrast, no significant difference in outcomes between the immunoparesis groups was seen for those treated with bortezomib or immunomodulatory drugs. At first progression, immunoparesis status did not impact response or survival of any regimen. Melphalan at first-line provided poorer outcomes for patients with significant immunoparesis, while bortezomib or immunomodulatory drugs were more likely to overcome the adverse prognosis associated with significant immunoparesis. Introduction\nAL amyloidosis is a disorder with considerable therapeutic challenges. The disease can produce profound organ dysfunction which may limit the intensity of the delivered treatment, and therefore treatment efficacy is impaired. Autologous stem cell transplantation (ASCT) is considered the treatment of choice, when applicable, given its superior long-term survival.21 However, for non-ASCT eligible patients, therapy selection based on baseline disease characteristics has not been well-developed. The lack of guidelines for treatment selection at diagnosis may lead to the selection of inappropriate treatment that would lead to irreversible organ damage and a shorter survival.\nRecently, we have reported that significant immunoparesis is an adverse prognostic factor in newly diagnosed AL amyloidosis.3 We proposed that immunoparesis assessment can be carried out by two methods. First, qualitatively, considering the number of uninvolved immunoglobulins below their lower limit of normal (LLN) and second, quantitatively, in which the average relative difference (ARD) of the uninvolved immunoglobulins from their respective lower limits is assessed. It was found that patients with significant immunoparesis (represented by either a reduction of all the uninvolved immunoglobulins below the LLN or by a negative ARD value) had a higher rate of treatment failure and reduced progression-free survival (PFS) and overall survival (OS) compared to patients with no or only moderate immunoparesis. The quantitative assessment was, however, shown to have a better discriminate power for survival. In this study we explored the results of selected treatment regimens at induction and first progression and analyzed these outcomes based on the ARD status at diagnosis.\nMethods\nSix hundred and eighty-one patients (n=681) with systemic AL amyloidosis seen at the Mayo Clinic (Rochester, MN, USA) within 90 days of diagnosis between January 1, 2005 and August 31, 2015 were included. Data were extracted from a prospectively maintained database. The median follow-up of the surviving patients is 53 months (range 3–135 months). All patients gave written informed consent to have their medical records reviewed. The Mayo Clinic Foundation Institutional Review Board (IRB) approved this study.\nPatients were excluded if they had prior treatment, amyloidosis associated with a lymphoproliferative disorder, an incidental positive bone marrow and/or fat aspirate without an amyloid-specific syndrome or a localized disease. Three hundred and seventeen patients who met inclusion criteria but lacked response evaluation data were not included in this study for the following reasons: no treatment/less than one cycle of treatment (n=58), lack of sufficient laboratory data for response evaluation, and/or early death rendering them inevaluable for response (n=259).\nThe diagnosis of AL amyloidosis was based on a tissue specimen positive for Congo red staining and with green birefringence under polarized light, followed by typing with immunohistochemistry, immunofluorescence, or mass spectrometry. All patients had immunoglobulin measurements before treatment. For immunoparesis assessment we used a quantitative measure, which utilizes the ARD of the uninvolved immunoglobulins. ARD was calculated as the mean value of the relative difference of the uninvolved immunoglobulins from their lower limit of normal (See the Online Supplementary File for a sample calculation). Based on this method, patients were stratified to those with a negative ARD value (i.e. significant immunoparesis) and those with a positive ARD value (i.e. no immunoparesis or modest immunoparesis only).\nTreatment regimens at induction and first progression were grouped into autologous stem cell transplant (ASCT) and non-transplant regimens. The latter category includes the following regimen categories: melphalan-based regimen, bortezomib-based regimen (which includes 4 patients at first progression treated with other proteasome inhibitors) immunomodulatory drugs (IMiD)-based regimen (thalidomide, lenalidomide or pomalidomide), and dexamethasone alone. Eligibility criteria for ASCT at our center have been previously described.4\nTwo-hundred and ninety four patients (43% of the study population) progressed during follow-up. Of these, 51 patients (17%) progressed but were not treated and 3 additional patients had treatment of an unknown type. Therefore, 240 patients are evaluable for response and survival at first progression. Details of the specific regimens used at first-line of treatment and at first progression can be viewed in the Online Supplementary Material. For assignment of ARD group at first progression, we applied the baseline ARD groups at diagnosis, which represents an intrinsic feature of the disease not influenced by treatment.\nThe Pearson χ test and the Kruskal-Wallis test were used to ascertain differences between nominal and continuous variables, respectively. Evaluation of response, PFS and OS were performed in accordance with consensus criteria,5 the Kaplan-Meier method was used to measure survival analysis. Univariate Cox proportional regression analysis was used to examine the relationship between ARD groups, regimen types and survival outcome. P values less than 0.05 were considered significant. All statistical analyses were performed on JMP software (SAS, Cary, NC, USA).\nResults Baseline characteristics\nThe median age of the 681 patients was 62 years [range 26–89]; 62% of patients were male. The median number of organs involved was 2 (range 1–4). The 2004 Mayo stage6 and the 2012 revised Mayo stage7 are listed in Table 1.\nFirst line treatment\nInduction treatment categories are listed in Table 1. A melphalan-based regimen was given to 32% of patients, bortezomib-based regimens to 19% of patients, an IMiD-based regimen to 5% of patients and dexamethasone alone for 2% of patients. Autologous stem cell transplant (ASCT) was performed in 32% of patients without prior induction, while an additional 10% of patients proceeded to ASCT following induction treatment making a total of 42% undergoing ASCT as a first-line treatment. There was no difference in treatment categories distribution, including ASCT, melphalan-based, bortezomib-based and IMiD-based regimens between immunoparesis groups (P=0.66), but not dexamethasone alone. Patients who underwent ASCT were younger (median age 59), with fewer organs involved (median one organ) and lower 2004 Mayo stage III (15%) and 2012 revised stages III–IV (25%), compared to patients treated with non-transplant regimens (median age 65; median involved organs 2; 2004 Mayo stage III 44%; 2012 revised stage III–IV 64%; all comparisons P<0.001). In patients who received non-transplant regimens, baseline characteristics were balanced between regimens in both immunoparesis groups (data not shown).\nHematological response to first-line treatment by immunoparesis status\nThe rate of very good partial response (VGPR) or better (≥VGPR) was 48% in patients with a negative ARD compared to 70% in patients with a positive ARD (P<0.001). While the rate of VGPR was similar between groups (25% and 26%, respectively), fewer patients in the negative ARD group reached a complete response (CR) compared to those with a positive ARD (23% vs. 44%). The rates of partial response and no response were 30% and 22% vs. 19% and 11%, respectively.\nThe rate of VGPR or better response by treatment categories can be seen in Figure 1. When comparing the ≥VGPR rate for each regimen between patients with a negative ARD to those with a positive ARD, the difference between groups was seen in those receiving ASCT (58% vs. 80%; P<0.001), a melphalan-based regimen (37% vs. 57%; P=0.006) and a bortezomib-based regimen (47% vs. 76%; P=0.001). However, no difference between groups was found in the IMiD-based regimen category (57% vs. 53%; P=0.81) or dexamethasone alone (25% vs. 50%; P=0.5)\nOrgan response by immunoparesis status\nOrgan response, (i.e. response in at least one involved organ) was seen in 57% of patients, and was significantly lower in patients with a negative ARD compared to those with a positive ARD (48% vs. 62%, respectively; P<0.001) (Figure 2). No difference in the achievement of organ response between the two immunoparesis groups was seen in those treated with ASCT (66% vs. 75%; P=0.12), a bortezomib-based regimen (48% vs. 56%; P=0.41), an IMiD-based regimen (54% vs. 43%; P=0.56) and dexamethasone alone (14% vs. 0%; P=0.59). However, for patients treated with a melphalan-based regimen, those with a negative ARD were less likely to achieve an organ response compared to those with a positive ARD (28% vs. 52%; P<0.001).\nEffect of immunoparesis status on progression-free survival and overall survival by regimen type\nPatients with a negative ARD, indicating significant immunoparesis, had a shorter PFS (median 16 months) compared to patients with a positive ARD [49 months, P<0.001; Hazard ratio (HR) 1.9, (95% confidence interval (CI) 1.5–2.3)]. The comparison of PFS between immunoparesis groups based on the given regimen demonstrated a significant difference in favor of the positive ARD group and was maintained in those undergoing ASCT [30 vs. 127 months, respectively, P<0.001; HR 2.3 (95% CI 1.6–3.2)] and for those treated with a melphalan-based regimen [11 vs. 27 months, P<0.001; HR 1.9 (95% CI 1.4–2.6)]. In contrast, no significant difference in PFS was noted between the negative and positive ARD groups in those treated with a bortezomib-based regimen [14 vs. 23 months, P=0.13; HR 1.4 (95% CI 0.9–2.3)], an IMiD-based regimen [20 vs. 13 months, P=0.84; HR 0.9 (95% CI 0.4–2)] or dexamethasone alone [5 vs. 6 months, P=0.66; HR 0.7 (95% CI 0.1–5)] (Figure 3).\nPatients with a negative ARD had a shorter OS (median 66 months) compared to patients with a positive ARD [median 127 months, P<0.001; HR 1.6, (95% CI 1.3–2)]. In patients who underwent ASCT, inferior OS was seen in patients with a negative ARD (median 108 months) compared to patients with a positive ARD [median not reached, P=0.01; HR 1.9, (95% CI 1.1–3)]. Similarly, patients with a negative ARD treated with a melphalan-based regimen had an inferior OS compared to patients with a positive ARD treated with the same regimen type [30 vs. 74 months, P=0.001; HR 1.7, (95% CI 1.2–2.5)]. However, no significant difference in OS between immunoparesis groups was observed for a bortezomib-based regimen [57 vs. 41 months, P=0.61; HR 1.2, (95% CI 0.6–2.0)], an IMiD-based regimen [32 vs. 16 months, P=0.4; HR 0.7, (95% CI 0.3–1.6)] or dexamethasone alone [20 months vs. median not reached, P=0.57; HR 1.8, (95% CI 0.3–34)] (Figure 4). Of note, patients with a positive ARD treated with an IMiD-based regimen had a significantly shorter OS compared to other non-transplant regimens in this group (P=0.01).\nTreatment at first progression\nThe progression rate in patients with a negative ARD was 53% compared to 39% in patients with a positive ARD (P<0.001). The median time to first progression was 14 months, shorter in patients with a negative ARD (12 months) compared to patients with a positive ARD (17 months; P=0.01). The characteristics of patients at first progression are listed in Table 2. The most common regimen used at first progression was bortezomib-based (53%), followed by IMiD-based (25%), melphalan-based (14%), ASCT (5%) and dexamethasone alone (3%). A different treatment distribution was noted at first progression by baseline immunoparesis status. Patients with a baseline negative ARD were more likely to receive a melphalan–based (18%) or an IMiD-based regimen (33%) compared to patients with a positive ARD (11% and 20%, respectively). In contrast, patients with a positive ARD were more likely to receive a bortezomib-based regimen (59%) compared to those with a negative ARD (44%). ASCT was used at a similar rate between groups (4% in the negative ARD groups and 6% in the positive ARD group) (P for all comparisons=0.02). Moreover, patients receiving a melphalan-based regimen at first progression were less likely to receive ASCT at first-line (30%) compared to other non-transplant regimens at first progression (49%; P=0.04), with no difference between ARD groups.\nResponse at first progression\nThe rate of VGPR or better at first progression did not differ between the immunoparesis groups. Fifty-seven percent of patients with a baseline negative ARD achieved ≥VGPR compared to 56% in patients with a positive baseline ARD (P=0.97). No difference was seen in the depth of response between groups (CR 19% vs. 15%; VGPR 23% vs. 28%, respectively; P=0.32). Organ response also did not differ between negative and positive ARD groups (42% vs. 40%; P=0.73).\nThe comparison of the rate of ≥VGPR by regimens between patients with a negative ARD to those with a positive ARD can be viewed in Figure 5. ASCT at first progression was utilized in 12 patients, and yielded the highest VGPR or better response rate (100% in patients with a negative ARD and 86% in patients with a positive ARD; P=0.46). As for the non-transplant regimens, no difference in the rate of ≥VGPR between the negative and positive ARD groups was noted for any regimen (melphalan-based regimen 29% vs. 43%, P=0.43; bortezomib-based 74% vs. 60%, P=0.14; IMiD-based 50% vs. 50%, P=1.0; dexamethasone alone 0% vs. 33%, P=0.39).\nSurvival from first progression\nPFS from first progression was comparable between those with a negative ARD and those with a positive ARD (median 17 vs. 20 months, respectively, P=0.95; HR 1 95% CI 0.7–1.4) (Figure 6A). No significant difference in PFS was seen between the negative and positive ARD groups for any regimen at first progression [ASCT median not reached in both, P=0.23; HR not estimable); melphalan-based median 8 months vs. 13 months, P=0.36; HR 1.5 (95% CI 0.6–3.5); bortezomib-based 27 vs. 22 months, P=0.64; HR 0.9 (95% CI 0.5–1.5); IMiD-based 17 months both, P=0.59; HR 0.8 (95% CI 0.4–1.7); dexamethasone alone 3 vs. 7 months, P=0.17; HR 5.5 (95% CI 0.2–138)].\nOS from first progression was similar between groups [median 42 months in those with a negative ARD compared to 47 months in those with a positive ARD, P=0.65; HR 1.1 (95%CI 0.8–1.5)] (Figure 6B). No significant difference in OS was seen between the negative and positive ARD groups for any given regimen at first progression [ASCT median not reached in both groups, P=0.18; HR not estimable; melphalan-based median 31 months vs. 40 months, P=0.9; HR 0.9 (95%CI 0.4–2.5); bortezomib-based median not reached vs. 72 months, P=0.42; HR 0.8 (95%CI 0.4–1.4); IMiD-based 54 months vs. 68 months, P=0.95; HR 1 (95%CI 0.5–2.2); dexamethasone alone 5 vs. 37 months, P=0.17; HR 5.5 (95%CI 0.2–138)].\nDiscussion\nThis study provides data on the differential response to various chemotherapeutic regimens in AL amyloidosis at first-line and first progression stratified by the immunoparesis status at diagnosis. For newly diagnosed patients, ASCT provided the best outcomes within each immunoparesis group, but with a greater benefit seen in patients without significant immunoparesis (i.e. positive ARD) compared to those with significant immunoparesis (i.e. negative ARD). For non-transplant first-line regimens, a comparison between immunoparesis groups shows that while the advantage for those with a positive ARD was seen with a melphalan-based regimen, this advantage disappeared with bortezomib or IMiD-based regimens. The response and outcome at first progression were comparable between immunoparesis groups, suggesting neutralization of the adverse prognostic effect of immunosuppression at progression. However, when the data was analyzed by regimen, melphalan-based and dexamethasone alone generally produced poorer response and survival compared to other regimens, possibly reflecting selection bias.\nASCT provided an improved survival rate in each immunoparesis group. The advantage of ASCT was seen as a higher rate of ≥VGPR as well as a longer PFS and OS. ASCT is, however, applicable only in a fraction of patients, which carry a more favorable prognosis, as reflected by younger age, a median of one involved organ and lower risk-stratified stage. In this study, ASCT (with or without prior induction) was performed in over 40% of patients, and reflects a referral bias. It is important to note that although patients with significant immunoparesis were shown to have more cardiac involvement, less renal involvement and a higher tumor burden (dFLC, bone marrow plasma cell percentage),3 they were as likely to proceed to ASCT as those without significant immunoparesis (41% vs. 43%, respectively). Even with ASCT, patients with a negative ARD had a lower ≥VGPR rate, PFS and OS compared to patients with a positive ARD, although organ response was achieved at a similar rate (66% vs. 75%, respectively). It appears that ASCT is the treatment of choice regardless of immunoparesis status, but response and response duration in patients with significant immunoparesis are lower than in those without significant immunoparesis.\nExploration of the treatment options in the non-transplant regimens reveals that patients with significant immunoparesis had a poorer response to melphalan-based regimens. This was reflected by a low rate of ≥VGPR (which represents the therapeutic endpoint in AL amyloidosis),7 as well as significantly lower organ response rate. In comparison, patients lacking significant immunoparesis treated with similar regimens had higher hematological (57%) and organ response (53%) rates. Moreover, a PFS and OS advantage in favor of patients without significant immunoparesis was seen in those treated with high-dose melphalan or low-intensity melphalan, but not for bortezomib or IMiDs. This finding suggests that in ASCT ineligible patients, melphalan has a greater impact in those without significant immunoparesis, while those with significant immunoparesis are less likely to benefit from melphalan. The reason for this is unclear, but might reflect different disease biology based on immunoparesis status. Melphalan, an alkylating agent is, unlike bortezomib and IMiDs, genotoxic.8 As such, it has the potential to impact DNA integrity and accelerate progression of a genomically unstable plasma cell clone. At progression, melphalan therapy produced the poorest results, which also supports this hypothesis. However, this clearly needs further investigation.\nWhile IMiDs produced a relatively good response rate and survival in patients with significant immunoparesis, they were associated with a reduced OS in patients without significant immunoparesis. IMiDs in AL amyloidosis are generally not well tolerated and produce modest benefit,109 and therefore are not considered as first-line treatment for most patients. Based on the data presented, the selection of an IMiD as first-line should be discouraged in those without significant immunoparesis but can be considered for those with significant immunoparesis. The number of patients treated with IMiDs in this study was small, so this conclusion must be taken with caution and should be confirmed by other studies. When dexamethasone alone was utilized, the results were generally poor.\nPatients at first progression were still able to achieve ≥VGPR in over 50% of patients in both groups, but had a shorter duration of response with a second-line of therapy. PFS and OS were comparable between patients with or without significant immunoparesis, independent of the salvage regimen. However, patients treated with melphalan-based regimens had poorer response, PFS and OS in immunoparesis groups. This may reflect a bias, as patients treated with low-dose melphalan at first progression were less likely to have been ASCT-eligible at diagnosis and carry a poorer prognosis.\nIn conclusion, first-line ASCT provides the best response and survival in patients with AL amyloidosis, irrespective of immunoparesis status. Better results for ASCT, however, were seen in those without significant immunoparesis. For non-transplant regimens, bortezomib and IMiDs were more likely to overcome the poorer prognosis associated with significant immunoparesis, while low-dose melphalan was associated with the least benefit for patients with significant immunoparesis. These findings should be assessed in prospective studies.\nFootnotes Check the online version for the most updated information on this article, online supplements, and information on authorship & disclosures: www.haematologica.org/content/101/9/1102 Received March 29, 2016. Accepted June 10, 2016. References D’Souza A, Dispenzieri A, Wirk B. Improved Outcomes After Autologous Hematopoietic Cell Transplantation for Light Chain Amyloidosis: A Center for International Blood and Marrow Transplant Research Study. J Clin Oncol.2015; 33(32):3741-3749. PubMedhttps://doi.org/10.1200/JCO.2015.62.4015Google Scholar Cordes S, Dispenzieri A, Lacy MQ. Ten-year survival after autologous stem cell transplantation for immunoglobulin light chain amyloidosis. Cancer.2012; 118(24):6105-6109. PubMedhttps://doi.org/10.1002/cncr.27660Google Scholar Muchtar E, Dispenzieri A, Kumar SK. Immunoparesis in newly diagnosed AL amyloidosis is a marker for response and survival. Leukemia.2016. https://doi.org/10.1038/leu.2016.140Google Scholar Dispenzieri A, Buadi F, Kumar SK. Treatment of Immunoglobulin Light Chain Amyloidosis: Mayo Stratification of Myeloma and Risk-Adapted Therapy (mSMART) Consensus Statement. Mayo Clin Proc.2015; 90(8):1054-1081. PubMedhttps://doi.org/10.1016/j.mayocp.2015.06.009Google Scholar Comenzo RL, Reece D, Palladini G. Consensus guidelines for the conduct and reporting of clinical trials in systemic light-chain amyloidosis. Leukemia.2012; 26(11):2317-2325. PubMedhttps://doi.org/10.1038/leu.2012.100Google Scholar Dispenzieri A, Gertz MA, Kyle RA. Prognostication of survival using cardiac troponins and N-terminal pro-brain natriuretic peptide in patients with primary systemic amyloidosis undergoing peripheral blood stem cell transplantation. Blood.2004; 104(6):1881-1887. PubMedhttps://doi.org/10.1182/blood-2004-01-0390Google Scholar Kumar S, Dispenzieri A, Lacy MQ. Revised prognostic staging system for light chain amyloidosis incorporating cardiac biomarkers and serum free light chain measurements. J Clin Oncol.2012; 30(9):989-995. PubMedhttps://doi.org/10.1200/JCO.2011.38.5724Google Scholar Ranaldi R, Palma S, Tanzarella C, Lascialfari A, Cinelli S, Pacchierotti F. Effect of p53 haploinsufficiency on melphalan-induced genotoxic effects in mouse bone marrow and peripheral blood. Mutat Res.2007; 615(1–2):57-65. PubMedhttps://doi.org/10.1016/j.mrfmmm.2006.10.001Google Scholar Dispenzieri A, Lacy MQ, Rajkumar SV. Poor tolerance to high doses of thalidomide in patients with primary systemic amyloidosis. Amyloid.2003; 10(4):257-261. PubMedhttps://doi.org/10.3109/13506120309041743Google Scholar Sanchorawala V, Wright DG, Rosenzweig M. Lenalidomide and dexamethasone in the treatment of AL amyloidosis: results of a phase 2 trial. Blood.2007; 109(2):492-496. PubMedhttps://doi.org/10.1182/blood-2006-07-030544Google Scholar", "pred_label": "__label__POS", "pred_score_pos": 0.9237267374992371}
{"content": "Cyclization via head-to-tail linkage of the termini of a peptide chain occurs in only a small percentage of proteins, but engenders the resultant cyclic proteins with exceptional stability. The mechanisms involved are poorly understood and this review attempts to summarize what is known of the events that lead to cyclization. Cyclic proteins are found in both prokaryotic and eukaryotic species. The prokaryotic circular proteins include the bacteriocins and pilins. The eukaryotic circular proteins in mammals include the theta defensins, found in rhesus macaques, and the retrocyclins. Two types of cyclic proteins have been found in plants, the sunflower trypsin inhibitor and the larger, more prolific, group known as cyclotides. The cyclotides from Oldenlandia affinis, the plant in which these cyclotides were first discovered, are processed by an asparaginyl endopeptidase which is a cysteine protease. Cysteine proteases are commonly associated with transpeptidation reactions, which, for suitable substrates can lead to cyclization events. These proteases cleave an amide bond and form an acyl enzyme intermediate before nucleophilic attack by the amine group of the N-terminal residue to form a peptide bond, resulting in a cyclic peptide.", "pred_label": "__label__POS", "pred_score_pos": 0.9424595236778259}
{"content": "Commercial Real Estate Law in Michigan\nIn Frankenmuth, Michigan, commercial real estate is any form of real property (land or permanent structures) being utilized for business purposes.\nCommercial real estate in Frankenmuth, Michigan is controlled by laws which differ significantly from state and local laws that apply to residential real estate.\nBuyers and renters of residential property enjoy some pretty considerable legal protections, because the law of most states presumes that shelter (being necessary to survive, for the most part) is more important than business. Therefore, many of these consumer protections don't apply to commercial real estate.\nThese include implied warranties of habitability, rent control, and covenants of use and quiet enjoyment, among various others. Of course, the most general protections, such as prohibiting the seller from actively concealing defects, apply to both.\nCommon Commercial Real Estate Law Issues in Frankenmuth, Michigan\nFinancing: The majority of small businesses in Frankenmuth, Michigan can't afford to make large real estate purchases with the money they have in the bank. Nonetheless, buying real estate is sometimes necessary for a business' survival. This problem is sometimes remedied by taking out a mortgage; a loan used to buy property, with that same property being used to secure the loan.\nDuty to Disclose Defects: It is of the utmost importance that sellers and lessors of commercial real estate be up front about any defects that might be present in the property. Failing to disclose them can be bad, and actively concealing them can be much worse. In general, if a defect is significant enough that it would influence a reasonable person's decision to buy a piece of property, and the seller knows about it, the seller should disclose it. Failure to disclose can have significant outcomes. If the buyer later discovers the defect, they can sue for the cost of repairing it, or for any reduction in the property's value caused by it. And, of course, if it causes any injuries, the buyer can sue the seller for those, as well.\nDuty to Inspect: Lest you believe that the duty to disclose defects relieves any duty of diligence on the part of the buyer, the law will not reward such lapses with a major cause of action. Buyers have a duty to conduct a reasonable inspection of the property before they buy it, normallyy with a licensed building inspector. If the buyer fails to do this, they won't be able to recover any damages for defects which they could have discovered through a reasonable inspection.\nEncumbrances: Encumbrances are defects of a different type: rather than physical defects, they are defects of title. In Frankenmuth, Michigan, an encumbrance is an interest in a piece of real estate held by a third party, such as covenants or easements. An easement is a right held by someone to use the property of someone else for a particular purpose. For instance, a person might have an easement on the land of another person, allowing them to cross the land to access a public road.\nCan a Frankenmuth, Michigan Attorney Help?\nThese issues can be very complicated, and most people consider such financially-weighty decisions to be very essential. If you are one of those people, it's a smart move to contact a Frankenmuth, Michigan real estate attorney if you are facing any of the issues discussed above.", "pred_label": "__label__POS", "pred_score_pos": 0.5137614011764526}
{"content": "For some women, frequent urination can be a sign of pregnancy. However, what if urinating is accompanied by pain whether it be a sign of pregnancy or even a dangerous condition of a particular disease?\nWhen pregnant, women will become frequent urination. This condition is generally normal and can be used as one of the early signs of pregnancy. Increased frequency of urination occurs because the body undergoes hormonal changes, as well as the enlarged uterus that suppress the bladder, causing frequent urination during pregnancy.\nWhile for urination accompanied by pain, although often also experienced by pregnant women, is not a sign of pregnancy. This condition is a symptom of certain diseases, such as bacterial vaginosis, chlamydia, endometriosis, genital herpes, gonorrhea, trichomoniasis, or urinary tract infection (UTI). Not only pregnant women who can experience pain when urinating, women who are active in sexual intercourse are also at risk of experiencing it.\nThe Cause of Pain When Urinating The Cause of Pain When Urinating\nPain during urination can be the most common symptoms when you have a urinary tract infection or UTI. This condition often occurs during pregnancy, because the influence of pregnancy hormones and changes in the size of the uterus that suppress the bladder can cause the emptying of the urine becomes disrupted.\nWomen are also at higher risk of developing urinary tract infections than men. This is because women's urinary tract is shorter than men's urinary tract. As a result, bacteria from around the anus can easily enter into the bladder and then infect it. Not only in the urinary tract, UTI can also occur when bacteria attack other urinary tract systems, such as kidney, ureter, and bladder (cystitis). Pregnant women, menopausal women, and women who are sexually active are at increased risk of bladder infections.\nSigns and symptoms that occur when a urinary tract infection, including:\nSensation of pain during urination Feeling often want to urinate The color of the urine is cloudy Fever The stench of urine Pain in the pelvis and lower abdomen There is blood in the urine\nIf you experience UTI symptoms during pregnancy, consult your doctor immediately for the right treatment. This needs to be done so that bacteria do not spread upwards and cause kidney infections (pyelonephritis) or cause complications in the fetus.\nPreventing Urinating Painfu l Preventing Urinating Painfu l\nUrinary tract infections may adversely affect the fetus, leading to premature birth, or low birth weight infants. Therefore, urinary tract infections during pregnancy should be addressed and prevented as much as possible. Here are some steps to prevent urinary tract infections, among others:\nDrink plenty of water. Fulfill your nutritional intake, such as vitamin C, beta-carotene, and zinc that can strengthen the immune system in fighting infection. Avoid holding back, because emptying your bladder can prevent bacteria from multiplying. After urinating or defecating, wipe off using a tissue or water from the front to the back (from the vagina to the anus). It aims to prevent the spread of bacteria from the anus to the vagina or to the urinary tract. Avoid foods and drinks that can irritate the bladder, such as spicy foods, artificial sweeteners, alcohol, caffeine, and sour fruits. Avoid feminine hygiene products in the form of sprays, powders, and antiseptic soaps that can irritate your urinary tract and female organs. Keep your urinary tract clean by changing underwear every day. In addition, choose underwear cotton and not too tight to prevent the feminine area becomes damp. Use condoms when having sex to prevent the occurrence of sexually transmitted diseases.\nThese simple things can prevent you from the pain of urination caused by UTI during pregnancy. However, if you are already exposed to the UTI, immediately consult a doctor to get the right handling. It should be done to prevent complications in pregnancy, such as premature babies, low infant weight, premature rupture of membranes, and preeclampsia.", "pred_label": "__label__POS", "pred_score_pos": 0.7667871713638306}
{"content": "SUMMARY: Unmanned aircraft systems can be an incredibly effective tool for companies looking to quickly and safely assess damage from major storms and disasters.\nPROBLEM: Exceptionally high floodwaters from Hurricane Matthew remain too deep for cars to traverse in some towns along the U.S. Carolina coast. Many buildings appear too damaged to accommodate inspections safely.\nSOLUTION: Companies are turning to UAS's to assist with the post-storm damage assessment and recovery effort. Verizon is using a unmanned aircraft operated by a partner company to assess potential damage at cellular site locations that are still covered by floodwater. After the drone flight, Verizon was able to send a boat with technicians who restored service near the Tar River Reservoir. Allstate insurance is also using drones to assess property damage in Savanah, Georgia. Instead of having a claims inspector ascend to the roof of a house to inspect damage from a fallen tree, Allstate dispatched a drone to capture a bird's-eye photo of the roof, which they deemed to be both faster and safer then having a person climb a compromised structure.", "pred_label": "__label__POS", "pred_score_pos": 0.890392541885376}
{"content": "A Student Emergency Fund was established in March to support Augsburg students with financial relief as we all grapple with the challenges of COVID-19. In these disruptive times, many students are experiencing the loss of income and jobs as segments of the economy shut down, struggles to provide for their families, obstacles in returning home to out-of-state residences, and uncertainty about their ability to finance their Augsburg education.\nWith this fund, students are able to request emergency funding for basic needs, including food, rent, transportation, and medication. They may also request funding for academic materials—such as books, supplies, laptop computer rentals, and wireless internet—to ensure their education is not impacted by a lack of attainable resources.\nGive to the Student Emergency Fund at augsburg.edu/giving.", "pred_label": "__label__POS", "pred_score_pos": 0.9757986068725586}
{"content": "Purpose\nTo provide Biophysical Society members, biophysicists, and others interested in the field with information related to biophysics research & careers, BPS activities, science news, member news, and public policy matters. BPS maintains accounts on Facebook, Instagram, LinkedIn, and Twitter.\nWhile social media is an effective communication and promotional tool, unguided engagement may lead to negative public reaction and consequences to BPS, therefore, it is important to develop a general framework and policy to guide our social media engagement to maximize effectiveness and minimize risks.\nSocial Media Posting Guidelines\nConsidering the diverse content that is shared on BPS social media, there are general guidelines that every post should adhere to and specific guidelines for posts around BPS sponsored events. Posts and Tweets, including reposts and retweets, should be in keeping with the Society’s mission, goals, and values. Posts should fall within the scientific efforts and/or expertise. Remember that BPS represents science and posts should be related to non-partisan science, which means that even reputable sources may not be suitable for citing or posting.\nGeneral Guidelines: Posts will be clear, concise and factual in nature. Questionable content must be verified with credible sources before posting. Any posts that share a link to a third-party website will be vetted and verified ahead of time. Posts will not communicate any financial, operational or proprietary information about BPS or its members. As BPS is a 501(c)3 organization, BPS may face tax consequences for public statements directly or indirectly supporting a political campaign or specific candidate for public office. No posts will identify any partisan political preferences or promote specific political campaigns. However, posts highlighting a general group of scientists or STEM candidates running for office is permissible. Posts will avoid using language that is deemed derogatory, offensive, or inflammatory. BPS representatives are barred from utilizing BPS social media assets to communicate their personal views or opinions. Violators will be subjected to administrative action. BPS accounts will make clear that its retweets or posting re-sharing content by another user does not indicate an endorsement of that user’s statement by BPS. Posts/reposts will be selected that represent the diversity of voices within the Society In the event BPS social media accounts receive a negative post or comment, the Social Media Manager will determine the best response or appropriate person(s) to whom to escalate the issue. In the event BPS social media accounts receive a request to engage on a specific policy issue, sign a petition, or share a particular viewpoint, these posts will be immediately shared with the Public Affairs Director for vetting. The Public Affairs Committee will consider relevant policy issues originating from social media to engage with. Specific Guidelines:\nBPS Events: No photos from BPS events will be shared that feature staff or members holding alcoholic beverages If BPS events are sponsored by outside organizations, posts will feature and thank our sponsors for their participation.\nMembers of Congress/Public Officials BPS posts will only tag and engage with the official account of the public officeholder. Staff will ensure no political accounts are tagged. BPS will engage with and support public office holders that support BPS positions and the research enterprise in general, regardless of their political affiliation.\nOfficial BPS Statements or Press Releases Due to character limits, it is often difficult to fully describe an official statement or press release on social media. Posts that share BPS positions or releases will always feature a link to the full statement/release and, to the best of their ability, summarize the position. Readers will be encouraged to view the full statement/release to ensure accurate and effective communication.\nChapters and Subgroups\nChapters and subgroups are required to adhere to all of the Society’s general social media guidelines. Chapters’ and subgroups’ social media presence is a powerful tool. It provides an avenue to build relationships and engage people. Official BPS Student Chapters and subgroups are an extension of the Biophysical Society. Every social media channel used by chapters and subgroups may be a first impression of the organization and should properly reflect the chapter, subgroup, institution, and Society. Each chapter and subgroup’s different social media channels should reflect the diverse voices that speak for the Biophysical Society. However, they should be representative of the Society’s missions and goals and identifiable as an official BPS associated account. All such accounts should feature the BPS logo along with the Chapter or subgroup logo in a clearly identifiable way.\nPart of the chapter and subgroup’s identity lies in the tone or voice that is used to represent the chapter, subgroup, institution, or the Society. Consider how the language you use affects or enhances the credibility of the chapter, subgroup, institution, and the Society. A motto often used when dealing with social media is that you can relax your tone, but not your standards. This means you should keep updates conversational and friendly, but always be a source of information and never uninformed speculation.\nViolation of BPS Social Media Policy Guidelines\nTo avoid any adverse repercussions, please adhere to the BPS Social Media Policy Guidelines. Violators may jeopardize their relationship with BPS and will be prohibited to interact on behalf of BPS and its affiliates.", "pred_label": "__label__POS", "pred_score_pos": 0.6933547854423523}
{"content": "Sentry Page Protection\nPlease Wait...\nScientific/Medical Question 13 What is the MDT and explain the role of 5 key MDT members\nMDT stands for multidisciplinary team. The MDT is crucial to integrated patient care, enabling successful collaboration of of professionals across the health and social care professions. Five team members are as follows: Excellent Answer\nExcellent Answer\nDoctors - doctors assess patients, request/perform investigations, prescribe medications and perform procedures. In conjunction with the patient , they strategise the direction that treatment will take.\nNurses: a nurse’s role involves planning, administering and evaluating patient care - such as diet, medications, monitoring vital signs, and ensuring record keeping.\nPharmacists: a clinical pharmacist is responsible for ensuring correct prescribing - be it checking that medications are correct, or that they follow national or local guidelines.\nPhysician associate: a physician associate is a medically trained healthcare professional who works alongside doctors to provide medical care. They can see patients, formulate diagnoses, and perform procedures. However, they cannot prescribe and must work within a scope and with a dedicated medical supervisor.\nOccupational therapist: occupational therapists have a degree in Occupational Therapy. They work in the rehabilitation of patients, with the goal of helping recovery in occupational and day-to-day skills. They also assess patient function across areas that are relevant to their return to everyday life, and develop a program to help them as needed.", "pred_label": "__label__POS", "pred_score_pos": 0.9988319277763367}
{"content": "Married ladies, be honest: Have you ever tried to plan your “escape” if things got too risky or too demanding? This wife shares why she decided to trade her escape plan for full commitment instead.\nFor as long as I can remember, I’ve been a planner, strategically and intentionally moving through life with plans A, B, and C intact — and, if I’m candid, marriage was no different. Even walking down the aisle, I knew that if this “Black love thing” didn’t work, I would have a plan to “abort mission” and safely route myself back to my independent, well-educated, much-loved single women’s utopia in Brooklyn.\nDon’t get me wrong, I was committed, but I’d be lying if I said there were no caveats.\nSee, before dating my husband, I had experienced a plethora of healthy, happy relationships, both romantic and platonic. However, there were always contingencies to keep me in control. As an independent woman, I felt I needed boundaries and a clear path out if things got too risky or too demanding. Ensuring that I always had an escape plan made me feel prepared in life and ultimately prepared for whatever deal-breakers a relationship, or a marriage, would (in my mind) inevitably bring my way. Looking back now, I realize that these beliefs were rooted in nothing more than fear.\nAs an independent woman, I felt I needed boundaries and a clear path out if things got too risky or too demanding.\nA year into our marriage, we got into one of our routinely, unruly quarterly arguments that resulted in me almost unconsciously plotting my exit. Like many times before, I thought through plans B, C, and D without saying a word, but this time was different. This time, instead of keeping the feud going for weeks, my husband came to me and said, “Let’s start over.” I agreed. I was skeptical, but amid my hesitation, I saw a glimmer of our growth.\nAfter we’d reconciled and had a chance to talk sensibly, my husband jokingly called me a “flight risk.” Offended, I reacted immediately with anger, and there went all of our growth right out the window. Sitting alone in the bathroom, with the notion of being compared to a fugitive top of mind, I realized that I’d been indeed behaving like someone in captivity contemplating an escape. What had once been my testament to “staying ready” and in control was consequently preventing me from living freely and choosing to love him wholeheartedly. He had joked, but the reality was, I was a flight risk, and we both knew I hadn’t been fully committed.\nI was a flight risk, and we both knew I hadn’t been fully committed.\nIt was apparent then, that if I wanted to experience the abundance of a loving, happy marriage, I would eventually need to abandon my marriage contingency plan and consciously choose to show up for our love and our marriage wholeheartedly, with no plan-B in-tact.\nIt was also the first time that I’d acknowledged that my crisis planning and what-if strategies were getting in the way. From the moment we’d said, “I do,” I’d been planning my exit to avoid marital challenges, mitigate generational hurt, and escape the possibility of disappointment. Marriage was the most permanent situation I’d ever been in, and, up until that point, I needed to believe there was a clear way for me to get out unscathed. Not knowing that sometimes coming out of a situation unscathed is a direct correlation to being uncommitted.\nChanging my mindset came with several unfamiliar challenges, but now I know that’s what marriage is all about. The first step I took was to remove the option of leaving altogether. Doing this took work and recalibration. I still needed options, but escaping couldn’t be one of them. Now, instead of contemplating jumping ship when things get hard and allowing fear to lead, I choose to lean-in and dig for multiple solutions. Sometimes I find them, sometimes I don’t, but usually, we explore the options together.\nThe second significant change I made was to relinquish some control. Marriage is a partnership, and we are equal stakeholders in our union. I had to learn to trust him and believe that as my husband, he has my best interest in mind.\nLastly, I had to get clear on what the actual deal-breakers were because let’s be honest, they exist. However, being transparent with each other about deal-breakers is key. This way, you know that you’re on the same page and honoring the same values.\nOh, and I still make contingency plans, but now they include alternatives and strategies for us both. I’ve learned that having a plan in place to mitigate our disagreements and help navigate our thoughts and emotions when things get rocky, is ideal.\nAs a married woman, most days I wake up uncertain, and with fewer plans than I did the morning before, but one thing is for sure, every day without a doubt I wake up, and I choose our love.", "pred_label": "__label__POS", "pred_score_pos": 0.5376498699188232}
{"content": "Abstract:\nObjective: To examine the relationship between poor effort, as measured by performance on the Word Memory Test, and baseline performance on ImPACT. Methods: Twenty-five undergraduate volunteers completed the immediate and delayed recall subscales of the WMT, as well as baseline testing on ImPACT. Results: Pearson’s correlations revealed a significant relationship between WMT scores (percent correct) and ImPACT processing speed composite score (r = .58; P = .003). Ten participants who failed the WMT (below 95% correct) had significantly faster ImPACT processing speed composite scores [F(1, 23) = 5.03; P = .035], as compared to 15 participants who completed the WMT at 95–100% correct. One-way ANOVAs revealed no significant between-groups differences on the other four ImPACT composite scores, including Impulse Control. Conclusions: Individuals performing with sub-optimal effort appear to process ImPACT stimuli faster than individuals completing the test with full effort. While this might suggest individuals providing sub-optimal effort are choosing any answer as quickly as possible, this is not reflected by poor performance on the other four composite scores. These results suggest that effort testing should be included in baseline concussion assessment, as decision time/processing speed is compromised by poor effort. In those cases where individuals provide sub-optimal effort, performance on baseline testing should be carefully scrutinized with particular emphasis on accuracy and speed of responses. Further research is required to determine the response patterns of individuals providing sub-optimal effort on specific neuropsychological test measures, especially those measuring response time on a computer.", "pred_label": "__label__POS", "pred_score_pos": 0.9999580979347229}
{"content": "Older people have lived a long time and may have had a lot of previous health problems. They may arrive in ED, convinced that they have a specific problem, “just like the last time”.\nImportant Note\nBecause older patients present atypically, we must consider their condition carefully. Keep an open mind:\nthe nausea associated with the current MI may feel like nausea of the previous ulcer; the flank pain of the current leaking AAA may feel the same as the previous ureteral stone; The unilateral headache of the current spontaneous subdural hematoma may feel similar to the hemicranial pain of the previous migraines!; The mild confusion of the current pneumonia may look to the family the same as the last time Mom had a UTI", "pred_label": "__label__POS", "pred_score_pos": 0.6876132488250732}
{"content": "Background\nMidwives are expected to support women with lactation initiation and maintenance. Midwifery students engaged in a simulation-based exercise (LactSim OSCE) where they role-played the clinician and the breastfeeding patient by wearing a high-fidelity breast model. We provided participants opportunities for reflecting in and on practice to compare their perceived self-confidence in clinical lactation skills to actual clinical performance. We also describe feasibility of implementing the LactSim OSCE with an emphasis on preparation and time spent on tasks during the OSCE.\nMethods\nAudio-video recordings from the LactSim OSCE were viewed and assessed using a technical skills checklist by an independent rater and by the study participants as part of the self-reflection. Mixed data on participants’ self-efficacy in clinical lactation, experience with the LactSim OSCE, and self-assessment of clinical performance were collected in survey instruments and a focus group. Time spent on each component and clinical lactation skill during the LactSim OSCE was documented.\nResults\nImmediately following the LactSim OSCE, participants’ confidence in clinical lactation was high (5.7/7), but after a guided video reflection exercise, their self-efficacy was 4.4/7. Participants spent approximately 2 of the allotted 10 min per case scenario discussing the OSCE logistics due to inadequate preparation. Participants spent approximately 2 min of the total encounter performing hands-on clinical lactation skills by touching, looking at, or using the high-fidelity breast model worn by their peer.", "pred_label": "__label__POS", "pred_score_pos": 0.9785836338996887}
{"content": "Abstract\nBartonella species were isolated from the blood of 63 of 325 Rattus norvegicus and 11 of 92 Rattus rattus from 13 sites in the United States and Portugal. Infection in both Rattus species ranged from 0% (e.g., 0/87) to ~60% (e.g., 35/62). A 337-bp fragment of the citrate synthase (gltA) gene amplified by polymerase chain reaction was sequenced from all 74 isolates. Isolates from R. norvegicus were most similar to Bartonella elizabethae, isolated previously from a patient with endocardil is (93%-100% sequence similarity), followed by Bartonella grahamii and other Bartonella species isolated from Old World rodents (Clethrionomys species, Mus musculus, and Rattus species). These data suggest that Rattus species are a reservoir host for pathogenic Bartonella species and are consistent with a hypothesized Old World origin for Bartonella species recovered from Rattus species introduced into the Americas.\nASJC Scopus subject areas Immunology and Allergy Infectious Diseases", "pred_label": "__label__POS", "pred_score_pos": 0.5834224224090576}
{"content": "What is Unconventional Oil?\nUnconventional oil refers to oil reserves that cannot be feasibly accessed using conventional drilling techniques. These reserves – notably tight oil, oil shale, and bitumen – must be extracted using novel methods. In contrast, conventional oil typically refers to crude oil which uses conventional vertical drilling techniques. There is no fixed definition for conventional and unconventional resources, and may be subject to change over time as technology and economics change\n1. Tight Oil\nTight oil describes reserves where the oil is trapped in geologic formations with low permeability, like shale or tight sandstone. The most common method of extraction for tight oil is hydraulic fracturing\n2. Oil Sands\nThe oil sands are large deposits of bitumen – grains of sand enveloped by layers of water and heavy oil. While the existence of bitumen has been known for quite some time, it is only recently (in the last 50 years) that technology and economic circumstances have allowed it to be extracted. These deposits, notably in Western Canada and Venezuala, can be accessed by surface mining or in-situ techniques.\nOil Shale\nOil shale is a fine grained sedimentary rock containing an organic compound known as kerogen, a precursor to oil. The extracted rock can be heated in an oxygen free environment to yield different hydrocarbon products; this is known as “retorting”\n3. Video Context\nUnconventional oil resources are typically more expensive to produce than conventional oil, often in the $40-$80/barrel range for production. However, the production of unconventional oil is increasing due to rising demand for fossil fuels and falling reserves of conventionals.\nThe unconventional oil “revolution” has drastically changed the world energy landscape. Advances in technology have made previously hard-to-access oil reserves more economically recoverable. These advancements have triggered changes in global oil supply, demand and transport. It has also affected global energy access and national economies. Perhaps the most notable effect is in the US, which is estimated to transition from a historical oil importer to a net exporter of oil by the end of the decade due to the exploitation of tight oil. This change in the US has drastically affected the global market for oil\n4. Dive deeper Recent blog posts about Unconventional Oil\nNo items found.", "pred_label": "__label__POS", "pred_score_pos": 0.9155619144439697}
{"content": "Anna Trenaman, Lucy Glover, Sebastian Hutchinson and David Horn\nNucleic Acids Res. 2019 Jul 26; 47(13): 7063–7077.\nPublished online 2019 May 25. doi: 10.1093/nar/gkz455 Abstract\nPost-transcriptional regulons coordinate the expression of groups of genes in eukaryotic cells, yet relatively few have been characterized. Parasitic trypanosomatids are particularly good models for studies on such mechanisms because they exhibit almost exclusive polycistronic, and unregulated, transcription. Here, we identify the Trypanosoma brucei ZC3H39/40 RNA-binding proteins as regulators of the respiratome; the mitochondrial electron transport chain (complexes I–IV) and the FoF1-ATP synthase (complex V). A high-throughput RNAi screen initially implicated both ZC3H proteins in variant surface glycoprotein (VSG) gene silencing. This link was confirmed and both proteins were shown to form a cytoplasmic ZC3H39/40 complex. Transcriptome and mRNA-interactome analyses indicated that the impact on VSG silencing was indirect, while the ZC3H39/40 complex specifically bound and stabilized transcripts encoding respiratome-complexes. Quantitative proteomic analyses revealed specific positive control of >20 components from complexes I, II and V. Our findings establish a link between the mitochondrial respiratome and VSG gene silencing in bloodstream form T. brucei. They also reveal a major respiratome regulon controlled by the conserved trypanosomatid ZC3H39/40 RNA-binding proteins.", "pred_label": "__label__POS", "pred_score_pos": 0.8051671981811523}
{"content": "EIGA 225/19 – Solvents for acetylene filling\nThe previous publication of EIGA 123, Code of Practice Acetylene, had become very large. During its review it is being split into separate publications on different topics. One of the topics is solvents for acetylene.\nAcetylene is a chemically unstable gas which can decompose violently under pressure. The acetylene gas is dissolved into a liquid solvent within the cylinder to improve the acetylene's chemical stability. This reduces the hazards involved in filling, transport and use.\nThis publication explains the safe use of solvents with acetylene. It describes the properties of the two solvents used for acetylene filling, acetone and dimethylformamide (DMF). It highlights the properties and the precautions to be taken when working with them.\nIt is intended for all personnel involved in the handling of acetone or DMF.\n17 October 2019", "pred_label": "__label__POS", "pred_score_pos": 0.7584952116012573}
{"content": "Seagrasses of the genus Posidonia can form an irregular seascape due to erosional processes exposing thick walls of organic matter-rich soils. However, little is known about the location and characteristics of these particular formations. Here we provide comprehensive estimates of organic carbon (Corg) storage in P. oceanica and P. australis meadows, while providing insight into their location and mechanisms of formation, and highlighting future research directions. Erosional reef escarpments are restricted to shallow highly productive P. oceanica meadows from the Mediterranean Sea and P. australis meadows from the Indian Ocean, and sustain the existence of Corg-rich deposits in surrounding meadows. The thickness of the mat escarpments can reach up to 3 m and their length can vary from few to hundreds meters. Mechanisms of formation appear to differ among sites, from naturally-induced escarpments by wave action and/or tidal flow to human-induced escarpments by dredging activities. The inter-twined remains of seagrass shoots within the sediment matrix consolidate the sandy substrate and hold the exposed Posidonia mat escarpments together, maintaining a semi-rigid structure. This phenomenon is unusual but of exceptional importance in marine biogeochemical cycles, revealing the largest Corg sinks among seagrasses worldwide (ranging from 15-176 kg Corg m-2 in 2 m-thick mats accumulated at 2-249 g Corg m-2 yr-1 over 300 to 3000 yr).", "pred_label": "__label__POS", "pred_score_pos": 0.8706767559051514}
{"content": "The Department of Public Health and Social Services issued a guidance relative to the minimum requirements in celebration of Halloween.\nDPHSS discourages traditional door-to-door trick-or-treating. Social gatherings of more than five individuals (i.e. Halloween and/or costume parties, haunted houses, etc.) are strictly prohibited.\nThe following guidelines are designed to minimize the risk of Covid-19 infection.\nThe DPHSS strongly encourages safe alternative activities to enjoying Halloween such as:\nDecorating and carving pumpkins with only those in the same household;\nDecorating your home;\nAdmiring Halloween decorations in your neighborhood at a distance;\nReading classic Halloween stories with those in the same household;\nBaking Halloween-themed cookies;\nWatching Halloween-themed movies or shows at your house;\nHiding Halloween treats in and around the house;\nParticipating in safe curbside trick-or-treating events sponsored by responsible businesses;\nHolding drive-by costume or car-decorating contests with judges who are physically distanced; and/or\nHolding a virtual Halloween costume contest so everyone can show off their costume.\nIn the event individuals choose to participate in traditional door-to-door trick-or-treating, DPHSS provides requirements below for all individuals involved.\nGeneral Guidance\nIndividuals experiencing flu-like symptoms or Covid-19-like symptoms are prohibited from participating in trick-or-treating.\nTrick-or-treat only with members of the same household.\nFace masks coverings must be worn by all individuals with the exception of children under the age of 2 or anyone who has difficulty breathing or a history of trouble breathing.\nHouseholds that have individuals under isolation or under quarantine due to Covid-19 are strictly prohibited from participating in any trick-or-treating activities.\nAll individuals participating in any trick-or-treating activities are advised to properly wash hands before and after each activity.\nConsider household members who may be at greater risk of complications if Covid-19 is brought into the home, such as those with underlying health conditions, women who are pregnant, or older family members.\nGuidance for Individuals/Households Distributing Treats\nWash hands properly before and after handling treats.\nWear a face mask at all times.\nAvoid direct contact with other trick-or-treaters and maintain social distancing of 6 feet or more.\nTreats should only be distributed outdoors.\nUse store-bought treats that are individually plastic-wrapped.\nAdults should be the individuals distributing treats while wearing a face mask and hand sanitizing between trick-or-treaters.\nIt is highly encouraged to practice safer, socially distant ways to conduct door-to-door trick-or-treating and distributing treats:\nSet up a table/station outdoors with individually bagged treats spaced apart for trick-or-treaters to take.\nUse a candy slide made of PVC pipe, or hanging treats from a wall or fence.\nIt is highly encouraged to use tongs, a spoon, or a tray to distribute treats. Children should not be allowed to retrieve their treats from a bowl or bag.\nCovid-19 positive individuals or individuals in quarantine are strictly prohibited from distributing any treats.\nGuidance for Parents/Guardians/Adults Responsible for Underage Trick-or-Treaters and for Trick-or-Treaters\nParents/Guardians should talk with their children about safety precautions and physical distancing in preparation of trick-or-treating.\nIf your child is at greater risk of complications from Covid-19, contact your doctor before allowing participation in Halloween activities.\nWear a face mask:\nHighly encouraged to make face masks a part of Halloween costumes.\nA costume mask is not a substitute for a face mask.\nDo NOT wear a costume mask over a cloth mask or a cloth mask over a costume mask as it may make breathing more difficult.\nPractice social distancing:\nStay at least 6 feet away from others who do not live in the same household\nIndividuals are more likely to get or spread Covid-19 when in close contact with others for a total of 15 minutes or more over a 24 hour period.\nWash your hands:\nBring hand sanitizer (with at least 60% alcohol) with you and use it after touching objects or other individuals.\nParents/Guardians: supervise young children using hand sanitizers.\nWash hands with soap and water for at least 20 seconds when you get home and before you consume any treats.\nUpon completion of trick-or-treating, it is highly advised to:\nLeave treats out for 48 hours before consuming.\nAllow children to eat only original, factory-wrapped treats. Avoid homemade treats made by strangers.\nGuidance for Business Operators Distributing Treats\nIt is highly discouraged for businesses to distribute treats in an enclosed or indoor area or in an in-person and non-curbside manner.\nOutdoor, drive-up, and curbside is highly preferable during the distribution of treats.\nAll other DPHSS guidance memos and minimum requirements must be followed to include, but not be limited to:\nFollow all occupancy requirements and limitations currently in effect.\nDo not allow any congregation of individuals.\nHave hand sanitizers readily available to all customers.\nEliminate all common seating, congregate, or play areas where children and others might gather.\nFollow all other DPHSS guidance memos and minimum requirements currently in effect.", "pred_label": "__label__POS", "pred_score_pos": 0.7842999696731567}
{"content": "Here are a few notes on meditation:\n-Your outlook during meditation should be positive and expectant but neutral. Don’t focus on or expect results. For example, in the Meditation on Twin Hearts, illumination rarely comes during a first session, though you begin accruing the benefits of greater energy and health immediately. Approach it as a climber approaches a mountain: He’s aware of the peak and expects to get there, yet he doesn’t focus on it. He looks only to the next handhold or foothold.\n-Some people experience shaking or strong emotions welling up within them. As indicated earlier, meditation is an indirect clearing technique, and trembling or sudden feelings are evidence of energetic blockages being cleared out and the emotions associated with those blockages being released. If you encounter any discomfort during meditation, respond according to your personal threshold. Some people breathe more deeply and continue with the meditation. If you wish, however, you can stop the session and sweep and clean the area where you feel discomfort. You can meditate later.\n-Both meditations should take about 20 minutes. In the Meditation on Twin Hearts, that includes about 10 minutes for blessing the earth and 10 minutes for illumination. As you gain experience, you may spend more time on the illumination portion.\n-Beginners may experience slight congestion in the chest or heart area as they bless the earth during the Meditation on Twin Hearts. If this is uncomfortable, simply sweep and clean the area after you are finished. If it gets too uncomfortable, stop your meditation, and sweep and clean the area. You can meditate later or the next day.\n-When you are able to hold simultaneous awareness on the point of light and the gap in the Meditation on Twin Hearts, you may experience an inner explosion of light. This is normal, though it can be startling at first. Again, respond according to your own personal comfort threshold. If you can, simply breathe deeply and feel the feeling of the experience. If you need to, stop meditating and close with giving thanks, then perform grounding.\nMore About this Book\nYour Hands Can Heal You: Pranic Healing Energy Remedies to Boost Vitality and Speed Recovery from Common Health Problems\nContinue Learning about Meditation\nImportant: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.", "pred_label": "__label__POS", "pred_score_pos": 0.7178592681884766}
{"content": "A recent study published by the National Bureau of Economic Research (NBER) suggests that cryptocurrency markets move depending on the type of attention they receive – unlike traditional financial markets. In contrast with other traditional financial assets, cryptocurrencies don't behave or respond to the same set of market factors as traditional financial instruments but instead, move more closely with \"cryptocurrency specific factors,\" according to the non-profit's report, which was published this week. These factors include investor attention and market momentum, described as the \"time-series cryptocurrency momentum at the daily and weekly frequencies.\"\nThe paper's authors, Yale University economists Yukun Liu and Aleh Tsyvinski, suggest that, contrary to public opinion, \"the markets do not view cryptocurrencies similarly to standard asset classes.\" The paper cited CoinDesk's bitcoin, ethereum and XRP price trackers (referring to XRP as \"ripple\") as the source of its market data. Using price data series over multi-year time frames, the paper compared actual returns to the projected returns using a standard finance pricing model known as the CAPM.\nRead more...\n#Google", "pred_label": "__label__POS", "pred_score_pos": 0.8130496144294739}
{"content": "Rabies is a deadly virus that damages the central nervous system of mammals. This zoonotic disease can spread to people and other animals, typically via bites from those already infected. Rabies often affects wildlife like raccoons, skunks, and bats, but it can easily affect domesticated cats and dogs.\nReports of cats with rabies exceed those in dogs, perhaps because more cats are allowed to roam free and may come into contact with rabid wildlife or stray animals.\nAfter a cat has been exposed to rabies, it can take weeks to months for signs to appear. Once the signs of rabies appear in a cat, death usually occurs within about a week. There is no treatment for rabies in animals. This is why rabies vaccination is absolutely essential for all cats.\nThe signs of rabies in cats are typically seen in three stages: prodromal, excitative, and paralytic.\n01 of 04 Bite Wound\nBefore signs of rabies appear, you may notice a bite wound or abscess on your cat. This might have come from wildlife, another cat, or even a dog, any of which may carry rabies.\nAny bite wound or other injury should be treated by a veterinarian as soon as possible. Discuss your cat's rabies vaccination history with your vet so you can understand the risk of them contracting this disease.\nIf the cat has previously been vaccinated against rabies, your vet may recommend re-vaccination after the bite, especially if the vaccine is overdue. This can boost immunity and prevent rabies from infecting the cat.\nIf the cat has never been vaccinated for rabies, then there is no treatment available. These animals typically need to be quarantined and observed for signs of rabies. Sadly, humane euthanasia is the only option once signs of rabies begin.\nThe typical incubation period of rabies in cats lasts one to three months after exposure, but it may last longer in some cases. During this time, the virus travels through the body to the nervous system, eventually reaching the brain. The signs of rabies infection appear after this incubation period. Once signs of rabies appear, death typically occurs within about a week.\nNote that cats may be able to spread rabies several days before signs appear.\n02 of 04 Prodromal Stage\nThis is when the first signs of rabies affect the cat's behavior. You may notice that your outgoing cat is suddenly shy and hiding. Fearful cats might even become more confident. The cat may become lethargic and the appetite may decrease.\nBehavior and personality changes vary by case; some cats will exhibit very noticeable personality changes as the virus takes its toll on the brain. Other cats will only show mild changes at first, making it difficult to make a definitive diagnosis.\nThe prodromal stage of rabies usually lasts two to three days.\n03 of 04 Excitative Stage\nDuring this second stage, cats tend to show more extreme behavior changes. They appear agitated and restless and often overreact to normal sights and sounds. Many cats will become aggressive for no apparent reason. They may attack people, other animals, and even objects without provocation.\nThe excitative stage can last one to seven days and may somewhat overlap the other stages.\n04 of 04 Paralytic Stage\nDuring the final stage of rabies, the cat develops weakness and eventually paralysis in the head, neck, and chest. The larynx will become paralyzed and the cat will no longer be able to vocalize or swallow. This is when the well-known sign of \"foaming at the mouth\" begins; if the cat is unable to swallow, salivation becomes excessive.\nAs weakness turns to paralysis, the muscles that control breathing can no longer function, leading to death.\nThe paralytic stage of rabies lasts two to four days and ultimately leads to death.\nIt's important to understand that each case of rabies is unique and the cat's signs may not match the typical signs described above.\nCats with known exposure to rabies or with any signs, even subtle ones, will need to be quarantined to protect people and other animals from exposure. Sick animals with suspected rabies will need to be euthanized.\nIf a cat with suspected rabies has bitten a person, that cat will need to be quarantined for ten days. This is because we know that death occurs soon after signs of rabies appear. If the cat does not die during the quarantine, then the bite could not have transmitted rabies to that person.\nThe only way to definitely diagnose rabies is through analysis of the brain tissue. After death, the brain must be sent to a pathologist for testing.", "pred_label": "__label__POS", "pred_score_pos": 0.5210928320884705}
{"content": "Abstract\nMedication adherence is essential in preventing adverse intermediate outcomes, but little is known on hard outcomes. The aims of this study were to determine the 1-year adherence to oral antihyperglycemic drugs (OADs) and to predict the risk of subsequent health outcomes among (non)adherent patients with diabetes.Using a large Swiss healthcare claims database from 2011 to 2014, we identified all patients aged ≥18 years with diabetes and treated with at least 1 OAD prescription. Adherence to OADs was measured as the proportion of days covered (PDC) over 1 year and subdivided into 2 categories: adherent (PDC ≥ 80%), nonadherent (PDC < 80%). We estimated the relative risk of hospitalization and mortality at follow-up using multivariate Cox proportional hazard models.Based on a sample of 26,713 patients, adherence to OADs was quite low: 42% of the patients achieved a PDC of ≥80% during the 1-year observation period. A 7% reduction in the hospitalization risk and a 10% reduction in the risk of mortality could be observed in adherent patients compared to nonadherent patients (hazard ratio [HR], 0.93 [95% CI, 0.89-0.97]; HR, 0.90 [95% CI, 0.82-0.99]). Subgroup analysis showed that an intensified diabetes therapy had no significant influence on the risk of both outcomes in adherent patients.Poor medication adherence increases the risk of subsequent hospitalizations and premature mortality in patient with diabetes, regardless of disease severity and comorbidities. This emphasizes the need for an earlier identification of patients with poor medication adherence. The awareness of physicians and patients regarding the importance of adherence in diabetes treatment should be increased.", "pred_label": "__label__POS", "pred_score_pos": 0.8541896939277649}
{"content": "NCASE Resource Library Featured Resources\nThis publication features some of the best resources, including webinars, briefs, and toolkits, available in the online NCASE Resource Library, developed for both practitioners and system builders.\nThese selected resources, curated by NCASE, offer ideas and information for OST system leaders to support recovery from COVID-19.\nThe NCASE Out-of-School Time Professional Development System-Building Toolkit was designed to assist states as they build professional development systems inclusive of school-age providers.\nSearch for Resources ? Search Results Filter By Reset Selections Expand All Filters Topics Resource type Publisher Search Results Filter By\nThis webinar explores how leaders and stakeholders in WA developed a vision and conducted a 3-year pilot for creating an accessible, equitable, and high-quality system of programs for school-age and youth development. The webinar shares what was learned about professional development and coaching supports, and standards and assessment tools.\nThis webinar examines promising practices and research to support quality in Family Child Care (FCC). Dr. Juliet Bromer of Erikson Institute is featured as a special guest, presenting research on a conceptual quality model and strategies most likely to support providers in increasing quality.\nThis guide compares purpose, structure, content, and technical properties of assessment tools for out-of-school time programs.\nThis resource provides a review of tools that programs can use to measure youth outcomes. The outcomes selected include communication, relationships and collaboration, critical thinking and decision-making, initiative, and self-direction. The review includes cost and evidence of reliability and validity.\nOn October 5, 2016 the National Center on Afterschool and Summer Enrichment and the National Center on Early Childhood Quality Assurance came together to offer an interactive webinar session to help better understand the needs of States, Territories, and Tribes around supporting school-age children in family child care.\nThis chapter summarizes the trends in QRIS re-visioning among the 20 states that received Race to the Top-Early Learning Challenge (ELC) grants. The trends include a move toward promoting school readiness, continuous quality improvement, family engagement, and a focus on teaching and learning.\nThis executive summary reports on a three-year study of Youth Program Quality Improvement in 87 sites in four states that included quality assessment, improvement plans, coaching by managers, and staff training. The approach led to higher quality instructions across programs even where there was manager turnover, low staff education, and varying adult-youth ratios.\nThis webinar defines child care deserts and explores how two organizations have developed data-driven analyses to identify where there is persistent undersupply. The data demonstrate that lack of child care disproportionately impacts rural communities, low-income communities, and Latino and American Indian and Alaska Native families.\nThis report examines data from the National Survey of Early Care and Education. It aims to better understand home-based care and the 3.7 million paid and unpaid family child care providers in the U.S. Although the focus is on children aged birth to five years, it also includes tabulations on home-based providers serving school-aged children in Table B.", "pred_label": "__label__POS", "pred_score_pos": 0.5383299589157104}
{"content": "Abstract\nThe transcription factor KLF2 regulates T cell trafficking by promoting expression of the lipid-binding receptor S1P\n1 and the selectin CD62L. Recently, it was proposed that KLF2 also represses the expression of chemokine receptors. We confirmed the upregulation of the chemokine receptor CXCR3 on KLF2-deficient T cells. However, we showed that this was a cell-nonautonomous effect, as revealed by CXCR3 upregulation on wild-type bystander cells in mixed bone-marrow chimeras with KLF2-deficient cells. Furthermore, KLF2-deficient T cells overproduced IL-4, leading to the upregulation of CXCR3 through an IL-4-receptor- and eomesodermin-dependent pathway. Consistent with the increased IL-4 production, we found high concentrations of serum IgE in mice with T cell-specific KLF2 deficiency. Our findings support a model where KLF2 regulates T cell trafficking by direct regulation of S1P 1 and CD62L and restrains spontaneous cytokine production in naive T cells. Bibliographical noteFunding Information:\nThe authors wish to thank Caitlin Dejong for preparing and shipping Eomes-deficient bones and Thirumalai Ramalingam and Thomas Wynn for providing IL-13R-deficient bones. Jerry Lingrel provided Klf2 fl mice. Jason Cyster provided reagents and assistance with anti-S1P 1 staining. Xiao Jie Ding and Jason Vevea provided excellent technical support. We thank Oludare Odumade and Amy Moran for helpful discussion and critical review of the manuscript. The authors declare no competing financial interests. This research was supported by NIH grants R01-AI39560 (to K.A.H.), R01-AI38903 (to S.C.J.), and T32-AI007313 (to M.A.W.).\nKeywords CELLIMMUNO MOLIMMUNO", "pred_label": "__label__POS", "pred_score_pos": 0.8304417133331299}
{"content": "Study design\nEcological\nStudy population and setting\nThe study objective was to examine potential racial/ethnic disparities in deaths from COVID-19. Deaths were reported to the National Vital Statistics System from May 1 to August 31, 2020, across the US, including all states and Washington DC, and excluding residents of US territories or US citizens in foreign countries. Age of death, race/ethnicity, sex, region of residence (South, Northeast, Midwest, West) and place of death (e.g. such as healthcare setting, hospice, nursing home or long-term care facility) were also reported. Death due to COVID-19 was recorded if COVID-19 was an underlying cause of the chain of events leading to death (92% of COVID-19 deaths), or a contributing cause of death (8% of COVID-19 deaths). In total, 114,411 COVID-19-associated deaths were identified.\nSummary of Main Findings\nOut of 114,411 COVID-19 deaths during the study period, the highest number occurred in May 2020 (37,940, 33.2%). Overall, the majority of those decreased were male (53.3%, 60,961), White (51.3%, 58,692) and 65 years of older (78.2%, 89, 469). Additionally, 24.2% were Hispanic (N=27,687) and 18.7% were Black (N=21,394), which are greater proportions than their proportion of the general population by 5.5% and 6.0% respectively. Deaths among Hispanic people increased by 10.1 percentage-points over the study period, reaching roughly 25% of all COVID-19 deaths by August 2020. The plurality of average deaths across the study period occurred in the South (45.7%, 52,285), though in May the South represented just over 20% of deaths compared to August where it made up over 60%. For place of death, the majority died in an inpatient healthcare facility (64.3%, 73,566) followed by a nursing home or long-term care facility (22.0%, 25,170). From May to August, the proportion of deaths due to COVID-19 increased in the South, while it noticeably reduced in the Northeast. The percentage of deaths among people >=65 years remained relatively stable from May to August.\nStudy Strengths\nUsing data from the NVSS, the study was able to collect data on all deaths to identify and describe those in the US who died from COVID-19. They also had relatively detailed data, including many different categories for the place of death, and were able to show changes over time in the proportion of deaths between census regions and in racial/ethnic groups.\nLimitations\nThe study did not have data on comorbid conditions or other contributing factors to death, which may have revealed further trends among racial/ethnic groups at increased risk for some of these conditions (such as diabetes, hypertension, etc.). The NVSS data may have delays in reporting, which would mean these numbers do not represent the deaths that occurred in these months, but only the reporting of deaths which may not track to real-time data. Additionally, the paper does not relate to deaths indirectly caused by the pandemic, such as individuals avoiding or delaying medical care. Another limitation was the dates of data available, from May through August 2020, which does not capture all deaths since the beginning of the pandemic.\nValue added\nThis study examines death data from the entire US during the pandemic, highlighting important health disparities across racial/ethnic groups and geographic regions.\nThis review was posted on: 2 November 2020", "pred_label": "__label__POS", "pred_score_pos": 0.7588661313056946}
{"content": "The Virginia Transportation Research Council performed a laboratory investigation to evaluate whether stockpiling a CCPR mixture using foamed asphalt and cement as an active filler had any negative consequences with respect to the mechanical properties of the mixture. The mechanical properties included indirect tensile strength and dynamic modulus. The study recommended allowing stockpiling of CCPR mixtures using foamed asphalt and cement as the active filler for up to 24 hours. The study recommended verification of the findings and recommendations through follow-up studies.\nVirginia Transportation Research Council Final Report No. FHWA/VTRC 19-R32, Virginia Department of Transportation, May 2019.", "pred_label": "__label__POS", "pred_score_pos": 0.6656142473220825}
{"content": "In its latest Office of the Future survey released by Canon, the findings reveals that all organizations surveyed across a range of verticals experienced a cyber threat over the past year.\nConducted by global tech market advisory firm ABI Research, the survey of more than one thousand U.S. IT professionals reveals three, pertinent cybersecurity threats, which are Malware and Ransomware, Compromised Devices, and Social Engineering.\nSurvey results include additional gaps, such as lack of appropriate cybersecurity spend across certain verticals; however, it also indicates hope, with nearly 25% of those surveyed stating that they are looking to increase investments in the key growth area of cloud security in the future.", "pred_label": "__label__POS", "pred_score_pos": 0.5330251455307007}
{"content": "ViiV’s HIV Drug, Tivicay, Launched in the UK\ndiagnosis Tivicay, Launched in the UK” src=”http://i57.tinypic.com/2re6t69.jpg” width=”164″ height=”147″ />HIV patients in the UK will from this week have another treatment option after ViiV Healthcare announced the launch of their once-daily drug, Tivicay (dolutegravir).\nThe integrase inhibitor was approved in Europe last month for HIV-1 in a broad patient population of treatment-naive and treatment-experienced adults and children aged 12 years and above (weighing at least 40kg) when used in combination with other antiretroviral agents.\nThe European regulatory approval was based on the results from four pivotal Phase III clinical trials where 2,557 adults received treatment with Tivicay or a comparator.\nIn one clinical study, called SINGLE, 88% of study participants on the Tivicay regimen were virologically suppressed versus 81% taking Atripla (efavirenz/emtricitabine/tenofovir) after 48 weeks’ treatment, and time to viral suppression was also reduced (28 days versus 84 days, respectively).\nTivicay blocks HIV replication by preventing viral DNA from integrating into the genetic material of human immune cells (T-cells), an essential step in the HIV replication cycle.\nAs Tivicay comes with the added convenience of once-daily dosing, and can be taken with or without food, in addition to being effective in both treatment-naive and treatment-experience patients, it is widely expected to become a key future player in HIV treatment.\nAnalysts have noted that Tivicay could generate annual sales of up to $2.1 billion by 2022 in the USA, Japan and five major EU markets of France, Germany, Italy, Spain and the UK, equating to 12.6% of the overall combined value of these markets.\nHowever, Tivicay is currently only available through private prescription in England while a decision on NHS funding is made. The decision regarding the access of Tivicay on the NHS in England is expected between May and July this year.\nSimilarly, the SMC will appraise the drug in Scotland and the AWMSG in Wales, with decisions anticipated in May and June, respectively.", "pred_label": "__label__POS", "pred_score_pos": 0.6880275011062622}
{"content": "When divorced parents live far apart, it’s common for children to live full-time and attend school under the care and custody of just one parent. Long-distance parenting arrangements often include spending the summer with the non-custodial parent or alternating holidays. These arrangements may also make provisions for staying in touch with children remotely. This year, […]\nManaging the divorce process is stressful, draining, and can be emotionally devastating. Divorce will affect every part of life and creates major upheaval of financial circumstances and living arrangements, contributing to instability and uncertainty. During such a volatile time when so much is at stake, the smartest move is to connect with a legal expert. […]\nThe beginning of a new school year is exciting. However, it also tends to create tension in custody arrangements since routines and schedules may shift. Parental custody is initially determined during the divorce proceedings, but over time it will be necessary to reevaluate the custody agreement to reflect life changes as your child grows up. […]\nDivorce can be difficult for anyone to go through at any time… even more so during a global pandemic. If you and your spouse have recently decided to go separate ways, here are few tips on how to cope with divorce during an already difficult time. Use Technology to Lean on Family and Friends for Support The […]\nThe COVID-19 pandemic has thrown many families into uncertainty. This is especially true for families of divorce, who face co-parenting challenges and difficult daily decisions even when everything is normal. With new rules in place globally, it’s essential that you follow the rules set by federal government and local officials in order to keep your […]\nParental rights can be terminated in Arizona when such a move is best for the child’s safety and welfare. While Arizona courts prefer both parents to remain active in the child’s life, judges also understand that this is not always possible. It is essential to understand that once the termination of parental rights occurs, it […]\nThe holidays are supposed to be special, but for many families, they can be stressful and emotionally charged following a divorce. When parents are determining holiday visitation schedules, it is always best to put the interests and well-being of the child first. Doing so will go a long way toward ensuring that everyone has an opportunity […]\nCan a parent who has sole legal custody/legal decision making deny visitation to their ex-spouse or ex-partner? It’s a sensitive topic and one that happens with significant regularity. The bottom line is that a parent with sole legal custody does not always have sole custody. In most cases, the courts grant joint physical parenting time to […]\nDivorce creates significant ripples in your finances. These include the loss of a second income, the need to maintain a separate home, coupled with alimony and child support payments. It also involves the division of marital assets, including retirement accounts and pension plans. A family attorney in Arizona can help you protect these assets as […]\nIt may be possible to modify your spousal support obligations. While you can’t modify a non-modifiable agreement, it is possible to adjust a modifiable agreement. You can request a modification if there is a significant change in circumstances. For instance, if your ex-spouse remarries, if you suffer a severe financial setback, or if there are […]", "pred_label": "__label__POS", "pred_score_pos": 0.5933938026428223}
{"content": "26/11/2019\nAt its fifteenth meeting, the China Analysis Group promoted insightful discussions on global environmental challenges shared by Brazil and China, highlighting priority topics for bilateral cooperation in the short, medium and long term, within and beyond the 2030 Agenda for Sustainable Development. Despite the huge potential for bilateral cooperation in areas ranging from bio-economy to climate- resilient cities, participants consensually noted a lack of bilateral frameworks dedicated to sustainable development between China and Brazil – for instance, the absence of a sub-committee aimed at environmental cooperation within the Sino-Brazilian High-Level Coordination and Cooperation Committee (COSBAN). Ultimately, better exploring the co-benefits associated to bilateral cooperation on shared environmental challenges – including but not restricted to climate change – could contribute to strengthening multilateral frameworks and global environmental cooperation.\nRead the full report here.\nCopyright © 2013 Cebri, Todos os direitos reservados.", "pred_label": "__label__POS", "pred_score_pos": 1.0000032186508179}
{"content": "This book constitutes revised selected papers from the 12th international Global Sourcing Workshop 2018, held in La Thuile, Italy, in February 2018. The 9 contributions included were carefully reviewed and selected from 40 submissions.\nThe book offers a review of the key topics in sourcing of services, populated with practical frameworks that serve as a tool kit to students and managers. The range of topics covered in this book is wide and diverse, offering micro and macro perspectives on successful sourcing of services. Case studies from various organizations, industries and countries are used extensively throughout the book, giving it a unique position within the current literature offering.", "pred_label": "__label__POS", "pred_score_pos": 0.9977779984474182}
{"content": "The All-Volunteer Force: The Debate by Lieutenant Colonel Paul Yingling Download the full article: The All-Volunteer Force: The Debate\nI'd like to share with\nSWJ readers the debate I've been having with current and former senior defense leaders on the deficiencies of the all-volunteer force.\nThis past February, I published \"The Founder's Wisdom\" in\nArmed Forces Journal. While the article addressed many aspects of Congressional and popular oversight of national security issues, the issue that provoked the strongest reaction was the portion concerning the all-volunteer military.\nRaising an Army is not merely a matter of labor economics - finding the right combination of wages, benefits and marketing strategies to fill job vacancies. Raising an Army is a profoundly political act with profoundly political consequences. The issues of who fights and who pays for America's wars are ultimately questions about our conceptions of justice and civic obligation. My hope is that our debate about the merits of the all-volunteer force will move beyond questions of wages and benefits, and focus on these larger issues of justice and civic obligation.\nAs this \"short-term struggle\" approaches its tenth year, cheerful portrayals of the AVF are no longer plausible. It's time for the United States to reconsider the wisdom of the all-volunteer force.\nI look forward to the always superb commentary by\nSWJ readers on this debate, and I hope that Dr. Gilroy and Mr. Ford will join us. Download the full article: The All-Volunteer Force: The Debate Lieutenant Colonel Paul L. Yingling is an Army officer who has served three tours of duty in Iraq and is currently a professor of security studies at the George C. Marshall Center in Garmisch, Germany. The views expressed here are the author's own and do not necessarily reflect those of the Army or Defense Department.", "pred_label": "__label__POS", "pred_score_pos": 0.5076538324356079}
{"content": "September 05, 2019\nArea(s) of Interest: Payor Issues and Reimbursement Practice Management\nThe California Health Care, Research and Prevention Tobacco Tax Act of 2016 (Prop 56) created new revenues dedicated to the Medi-Cal program. Physicians receive supplemental payments in both fee-for-service and Medi-Cal managed care when providing Medi-Cal services under certain CPT codes.\nWhile the California Department of Health Care Services (DHCS) began disbursing the FY 2018-2019 supplemental payments in fee-for-service Medi-Cal last fall, federal approval of the supplemental Medi-Cal managed care payments was delayed until February.\nDHCS began dispersing the FY 2018-2019 funds to the managed care plans as part of its capitated payments in March. This includes both the go-forward payments and the retroactive payment for clean claims or accepted encounter data with dates of service between July 1, 2018, and the date the plan received the Prop 56 funds.\nPer DHCS instructions,\nfor clean claims or accepted encounters received, plans are required to issue supplemental payments to qualifying physicians within 90-days of receipt of the funds from the DHCS. DHCS clarified in these instructions that the 90-day timeframe for distribution of funds also applies to the plan’s delegated groups. Additionally, the DHCS is requiring plans to demonstrate that 95%of the funds were distributed to providers or refund the funds to DHCS.\nThe California Medical Association (CMA) surveyed the plans to determine which entity, plan or delegated group would be responsible for distributing payments and has created a Prop 56 Payment Source Table. Practices that have not received their supplemental payments, are encouraged to contact the plan or delegated group responsible for distributing payments. Physicians can utilize the payment source information along with the plan contacts table for additional information on who to contact regarding any underpayments.\nHow do I know if I’ve been paid correctly?\nCMA recently published an updated Prop 56 Payment Monitoring Worksheet to help physicians determine whether they have been paid correctly based on the FY 18-19 supplemental payment amounts (utilize the 2018-2019 worksheet).\nIs any physician action required to receive the supplemental payments?\nIf you are submitting claims to the managed care plans and are reimbursed on a fee-for-service basis, there is no additional action required. Payments should be automatic.\nHowever, physicians who have a capitated contract with either a Medi-Cal managed care plan or one of its delegated entities for eligible services must submit encounter data to the payor in order to receive the supplemental funds. Without the encounter data, the plan or its delegated entity will be unable to determine the services eligible for payment, which will result in non-payment of the supplemental funds. If you are unsure how to submit encounter data, contact the plan or delegated entity for more information.\nMore information on Prop 56 can be found on the DHCS website.\nPhysicians with questions or concerns can contact CMA’s Reimbursement Helpline at (888) 401-5911 or economicservices@cmadocs.org.", "pred_label": "__label__POS", "pred_score_pos": 0.9639959931373596}
{"content": "Since 2013, we have helped organizations secure more than $60M funding for our clients. We have experience in developing and crafting high-quality highly-competitive proposals to foundations, corporate grantmakers, and government funders at every level.\nOn average, we provide a return of ~$58 for every $1 spent on SBIR/STTR Phase I proposal preparation costs. For other federal funding, outside of SBIR/STTR – where the proposal budgets are multi-year, we provide a return well over a ~$100 for every $1 spent.\nBiomedical Advanced Research & Development Authority (BARDA) Defense Advanced Research Projects Agency (DARPA) Department of Agriculture (USDA) Department of Commerce – National Oceanic and Atmospheric Administration (NOAA) Department of Commerce – National Institute of Standards and Technology (NIST) Department of Defense (DoD) – Army, Navy, Air Force, US Special Operations Command, Defense Logistics Agency, and the Defense Health Program. Department of Education/Institute of Education Sciences (ED/IES) Department of Energy (DoE) Department of Homeland Security (DHS) Department of Transportation (DOT) Environmental Protection Agency (EPA) National Aeronautics and Space Administration (NASA) National Institutes of Health (NIH) National Science Foundation (NSF)\nAdditionally, outside of SBIR/STTR and economic development focused proposals, we do have extensive experience with some of the following federal agencies and focus areas. If you do not see an agency listed, we do encourage you to ask us about it.\nThe U.S. Agency for International Development (USAID) with a strong focus on American Schools and Hospitals Abroad (ASHA) and Development Innovation Ventures (DIV). As well as economic and humanitarian assistance. U.S. Department of Agriculture (USDA) with a focus on innovation and technology as well as product safety and conservation efforts. U.S. Department of Commerce (DOC) with a focus on economic development and technological advancement through vigilance in international trade policy, domestic business policy & growth, and promoting economic progress at all levels. U.S. Department of Defense (DOD) with a focus on peacekeeping and war-fighting efforts, Homeland Security, evacuation, and humanitarian causes. U.S. Department of Education with a focus on STEM aimed at elementary secondary and postsecondary education student and staff support services such as teacher professional development, after-school programming (ASP), out of school time (OST), 21st CCLC, School Improvement, MSP, API, counseling. As well as a focus on TRIO, Title III, Title V, TAACCCT, Title III, PBIS/MTSS, NSF-MSP/NRT/RET/REU, FIPSE, and Migrant Education. U.S. Department of Energy (DOE) with a focus on scientific and technological innovation in support of that goal; and to ensure the environmental cleanup of the national nuclear weapons complex. U.S. Department of Health and Human Services with a focus on Emergency Preparedness & Response, Education & Training, and Public Health & Safety. National Institute of Health (NIH) with a focus on R01, R41, R42, R43, R44, U43, U44, SB1, UB1 National Science Foundation (NSF) with a focus on science, to advance the national health, prosperity, and welfare, and to secure the national defense.", "pred_label": "__label__POS", "pred_score_pos": 0.6623906493186951}
{"content": "The Global Cloud Storage Market size is expected to reach $100.8 billion by 2023, rising at a market growth of 22% CAGR during the forecast period. Cloud storage is a service model that offers a platform to maintain, manage, and backup data remotely and at the same time, ensure data availability to users over a network (typically the Internet). The cloud data storage services are paid on a per-consumption, and monthly rate. Though the per-gigabyte cost is cheaper, the cloud storage providers have nevertheless, added operating expenses, making the technology relatively expensive. Rapid adoption of hybrid cloud storage, growing need for enterprise mobility for improved efficiency, significant growth in Internet of Things (IoT), and need for lower Capital Expenditure (CAPEX) and Operational Expenditure (OPEX) are the factors that drive the growth of the market during the forecast period.Read »", "pred_label": "__label__POS", "pred_score_pos": 0.6181317567825317}
{"content": "Loading Dock Safety Tips\nLoading docks present significant challenges for safety-conscious managers. However, with planning and preparation, workers can use the loading dock area safely. The keys to making this area as safe as possible include understanding the present loading dock hazards and creating a plan to mitigate them. These safety tips will make this process easier for you.\nLoading Dock Dangers\nDangers abound around loading docks for the unwary. The Occupational Safety and Health Administration (OSHA) identifies two main hazards on the docks themselves — slipping on wet or icy surfaces or falling off the side of the dock. However, these dangers are far from the only hazards workers face when on or near the loading dock.\nOther dangers that could occur in the dock area come from the vehicles and equipment used. For instance, improperly chocked trailer wheels could lead to injuries from the trailer rolling. Forklifts create hazards both from workers acting carelessly around them and from the carbon monoxide their engines put out.\nTo mitigate these hazards, scrutinize the dock area. Prevent falls by installing a loading dock safety chain or other barriers to safeguard against people stepping off the edges. Where you cannot install barriers, paint the floor to alert workers and forklift drivers of hazards. Post signs to indicate nearby fall hazards.\nKeep surfaces dry and clean when possible. Since many loading docks are exposed to the elements, this may not always be possible. Post warning signs in case of wet conditions outside that could cause the dock surface to become slippery.\nTrain forklift workers and loading dock employees on safe practices around forklifts. Plus, keep the area well-ventilated to prevent carbon monoxide poisoning.\nEven by taking these precautions to prevent accidents from occurring, workers still must take an active role in following good safety practices around the loading dock. Plus, you must have the right safety equipment to make those practices easier for workers to follow.\nLoading Dock Safety Procedures\nWorkers need to take an active role in preventing loading dock injuries. First, create a loading dock safety guide to use during training your employees in best practices when working in this area. This training guide will ensure every worker near the dock knows the potential hazards and understands how to avoid endangering themselves and others. For training, follow the guidelines of this loading dock safety checklist for your workers:\n1. Train for Forklift Safety\nFirst, forklift safety must become paramount for operators and pedestrians. Never allow anyone not trained in safe forklift practices to operate one. Also, never let anyone under 18 operate a forklift, per OSHA guidelines.\nWhen driving a forklift, the driver should use their horn to alert dockworkers of their presence. Additionally, nearby workers must take care not to distract the driver or attempt to ride the forklift.\nDrivers must use safe practices when lifting, moving and lowering loads. Operators should know the load capacity of the forklift and never attempt to exceed that when moving materials.\nOperators should also maintain speeds of 5 miles per hour or less in main warehouse spaces with clearly defined forklift paths. However, for areas near the loading dock, the drivers should slow down to accommodate more people and potentially slippery conditions.\nMake sure the area around the loading dock has enough clearance for a forklift’s safe passage. Preparing the dock for safety may include installing barriers or painting the floor to make edges more visible.\n2. Be Aware of the Surroundings\nTeach all workers to watch their surroundings for hazards. For instance, every employee should know when a forklift or trailer is nearby. Additionally, they must stay alert to changing conditions, such as loads moving into or out of the trailer or weather conditions that turn wet, making the dock slippery.\nPart of awareness includes wearing personal protective equipment such as helmets, ear protection and eye gear. Show workers where warning signs, loading dock safety lights, barriers and other visible features are to prevent incidents.\nDo not allow employees not trained in safety procedures near the loading dock. Keeping untrained workers away ensures that only those most aware of the required safety practices will be in the area.\n3. Use Safe Practices Around Trailers\nEmployees must know how to work safely when a trailer parks at the dock. First, someone must secure the trailer’s wheels with wheel chocks. These prevent the vehicle from rolling, opening a gap between the truck and the dock or causing a crushing injury.\nRequest that truck drivers use auditory sounds to signal spotters to help direct the trailer safely to the dock. When a truck announces its arrival, other workers must clear the area. Find an auditory or visual means of alerting the driver that their trailer does not have any workers in it and it is safe for them to drive away from the dock. This prevents accidents caused by workers in the trailer or on the dock plate.\nLastly, when moving materials, workers should wrap pallets to prevent contents from shifting and falling.\n4. Lift Correctly\nFor any workers manually lifting products, teach them safe lifting techniques. Back braces will not provide enough support to make up for poor lifting methods. Workers should bend at the knees and lift with the legs instead of bending at the waist. Employees should avoid moving items from shoulder height. Instead, they should bring the product down to a safer lifting level with lifting equipment. If an item exceeds their individual lifting capabilities, they should request a co-worker to help them move it.\nWhen carrying or placing goods, workers should limit the twisting motions they make. Instead of twisting the trunk to make a turn, employees should slowly turn their feet in the desired direction.\n5. Train Workers on Safe Use of Dock Levelers and Other Equipment\nAny workers using equipment around a loading dock need to know how to do so safely. Plus, they should have the training to identify when the equipment requires maintenance or repairs to restore its operation. For example, when using the dock levelers, workers need to alert others in the area before raising or lowering the leveler.\nNecessary Loading Dock Safety Equipment\nTraining workers is crucial to safety. However, you must also have fully functioning safety equipment around the loading dock. This machinery augments the safety training and prevention strategies your workers use. Combined, these things minimize the chances of an accident occurring in the loading dock area. Everything from barriers, signs, lights, overhead doors and dock levelers improves the area’s safety and is crucial to protecting the space.\nLoading Dock Safety Barriers\nSafety barriers include gates and chains that prevent people from walking into prohibited areas. For instance, you should install a loading dock safety gate or barrier to keep people and vehicles away from the dock’s drop-off edges.\nSafety barriers protect workers and forklifts from one of the most common loading dock hazards — falling off edges. These barriers should have a coloring that makes them highly visible. Train workers to never jump over or bypass the barriers for their protection.\nOSHA requires barriers to protect places where a drop-off measures 4 feet or more. However, even without such a significant drop, you should still consider installing barriers or using bright paint on the ground to indicate the elevation change.\nLoading Dock Safety Signs\nSafety signs provide a visual reminder of the hazards present at the loading dock. These signs should never replace good safety training — they should supplement it. During education sessions, show workers what the safety signs look like and what they mean. When employees encounter these at the loading dock, they will know immediately how to avoid problems indicated in the area.\nThese visual indicators should warn of slippery spots, drop-offs and fall hazards. Also, signs should warn workers of carbon monoxide dangers from the exhaust of forklifts or other engines operating at the loading dock.\nAdequate Lighting and Warning Lights\nThe loading dock’s lighting is crucial because workers rely on visual signals to warn them of danger or inform them to take instructions. Many employees at a loading dock may wear ear protection, making it harder for them to hear voices or auditory instructions. Therefore, you must have enough light available so workers can clearly see signage, co-workers, forklifts and floor markings, regardless of the conditions outside.\nRelated to the ambient lighting that makes the area easier to see is the use of warning lights needed for communication. For example, after you install lights to communicate with truck drivers, spotters can use a red light to tell the driver when to cut off the engine and a green light to inform them of when they can safely drive away from the dock.\nLights also play a role in communicating with workers. For example, inside the warehouse, a red light could indicate that the loading dock is not safe to enter or is not in operation. A green light signals active loading or unloading and safe conditions for trained workers to enter.\nCommunication lights can also show when to raise or lower dock levelers. The dock leveler creates a safe bridge between the dock and the trailer. However, if moved into place too soon or moved away too early, an accident could occur. Specific lights activated by the truck spotter can let the dock leveler operator know when to turn on the device for safe movement.\nOnce the dock leveler falls into place, the operator can turn the warehouse signal to green to let workers onto the loading dock to start unloading or loading the truck.\nWell-Maintained Overhead Doors\nYour warehouse’s overhead doors must safely open, close and stay in position as needed. Poorly maintained doors could refuse to open or fall unexpectedly. Schedule regular inspections every 5,000 cycles and make necessary repairs to keep these doors operating properly.\nProperly Operating Dock Levelers\nThe dock levelers play an important part in the area’s safety. These devices must fully support any equipment, personnel and loads moved between the truck and warehouse.\nFirst, you must choose the correct load capacity for the leveler. Capacities generally range between 25,000 and 80,000 pounds. However, some can support even more weight — up to 100,000 pounds.\nNext, choose the correct type of dock leveler. Vertical models store upright and lay flat to the truck bed. However, other types such as hydraulic, air-powered and mechanical dock levelers sit in the pit and raise to the truck bed. For docks that do not have much space between the floor and truck, an edge-of-dock leveler may suffice. This type of leveler installs at the floor level instead of in the pit and has a smaller surface to bridge to the truck.\nAlways have a trained worker operate the dock leveler. This person needs to ensure that others first clear the area before deploying the leveler. The truck spotter’s signals help the leveler operator know when the truck reaches a safe position for putting the dock leveler in place.\nDock Leveler Maintenance and Repair\nMake sure the dock leveler operates properly. Consider a similar maintenance schedule to the one you use for the overhead doors — you can employ this for servicing the warehouse’s dock levelers. These two devices will have similar amounts of usage, so a corresponding upkeep plan will be beneficial.\nScheduling regular maintenance of dock levelers ensures they operate safely and efficiently. Poor functioning of a dock leveler wastes time. Workers who attempt to fix problems themselves could get hurt.\nOne example of poor maintenance of a dock leveler happened to a truck driver who attempted to deploy a poorly lubricated leveler alone. The lack of lubrication caused force to build in the lip extender, which unexpectedly sprang open and pinched the driver’s hand, causing injury.\nWhen a dock leveler has a known problem, tag the equipment and avoid letting anyone use it until after an expert repairs it. When workers think a damaged dock leveler is available, they may feel it’s safe to use any workaround measures they can think of. However, using dock levelers in ways other than their recommended directions could lead to problems. Conducting regular inspections of dock levelers and marking those with issues will prevent such incidents.\nImprove Safety at Your Loading Dock With the Right Dock Leveler\nHaving a safer working environment protects employees from injuries, prevents losses caused by accident investigation and ensures productivity. Since the loading dock functions as a key component of your warehouse, you must find ways to reduce this area’s inherent hazards. Posting a loading dock safety checklist, training workers, having the right equipment and maintaining your dock leveler will all serve this purpose.\nIf your facility needs a new dock leveler, request a quote from us at idc-Automatic. We can help you find the safest option for your warehouse needs that meets your size requirements. As with all aspects of warehouse safety, starting with the right equipment can go a long way toward preventing injuries. Let us help you get the loading dock pieces your company needs to optimize safety.", "pred_label": "__label__POS", "pred_score_pos": 0.6760627031326294}
{"content": "Though wearing a face covering to prevent the spread of COVID-19 is crucial, it isn't particularly comfortable! This can raise issues with compliance, especially when it comes to children and young people. To help, the experts at Jobskin have been hard at work creating a new range of extra-comfortable face masks, which are now available in a selection of the most popular school uniform colours: Black, Blue and Red.\nPhysical social distancing is a good way to help prevent the transfer of coronavirus between people but in many situations, including the school environment, maintaining the recommended distance of two metres between people can be difficult, if not impossible. That's where the mask comes into play: by providing a physical barrier that prevents droplets from being released while breathing, the mask further improves the wearer's chances of staying safe.\nDisposable face masks are a common sight but, though they are convenient, they are not particularly kind to the environment. A washable and thus reusable face mask is therefore a much more sustainable choice and also delivers cost-savings. Our reusable face masks feature an innovative fixing device: instead of elastic ear straps, the straps on our masks fasten securely behind the head to deliver increased comfort.\nNew Comfort-Fit face masks from Jobskin, available in three different sizes, are made from the highest quality fabrics used widely across our range of garments, giving them excellent breathability and allowing them to be used over and over again. In addition to the back-to-school range in Blue, Black and Red, we also supply masks with a selection of fun prints, including Construction, Safari and Hearts & Flowers. The masks are either sold singly or as cost-effective packs of three: wash, wear and one-for-spare!\nDiscover more details about our new range of face masks on the Jobskin website. Stay safe!", "pred_label": "__label__POS", "pred_score_pos": 0.8581974506378174}
{"content": "Treatment of splanchnic vein thrombosis (SVT) is challenging and evidence to guide therapeutic decisions remains scarce. The objective of this systematic review and meta-analysis was to determine the efficacy and safety of anticoagulant therapy for SVT. MEDLINE, EMBASE, and Clinicaltrial.gov were searched from inception up to December 2019 without language restrictions to include observational studies and randomized controlled trials reporting radiological or clinical outcomes in patients with SVT. Pooled proportions and risk ratios (RR) with 95% confidence intervals (CI) were calculated using a random-effects model. Of 4312 records identified by the search, 97 studies including 7969 patients were analyzed. In patients receiving anticoagulation, the rates of SVT recanalization, SVT progression, recurrent VTE, major bleeding, and overall mortality were 58% (95% CI, 51-64), 5% (95% CI, 3-7), 11% (95% CI, 8-15), 9% (95% CI, 7-12), and 11% (95% CI, 9-14), respectively. The corresponding values in patients without anticoagulation were 22% (95% CI, 15-31), 15% (95% CI, 8-27), 14% (95% CI, 9-21), 16% (95% CI, 13-20), and 25% (95% CI, 20-31). Compared with no treatment, anticoagulant therapy obtained higher recanalization (RR 2.39; 95% CI, 1.66-3.44) and lower thrombosis progression (RR 0.24; 95% CI, 0.13-0.42), major bleeding (RR 0.73; 95% CI, 0.58-0.92), and overall mortality (RR 0.45; 95% CI, 0.33-0.60). These results demonstrate that anticoagulant therapy improves SVT recanalization and reduces the risk of thrombosis progression without increasing major bleeding. The incidence of recurrent VTE remains substantial also in anticoagulated patients. Effects were consistent across different subgroups of patients.", "pred_label": "__label__POS", "pred_score_pos": 0.6742696762084961}
{"content": "Abstract\nThinking about misleading higher-order evidence naturally leads to a puzzle about epistemic rationality: If one’s total evidence can be radically misleading regarding itself, then two widely-accepted requirements of rationality come into conflict, suggesting that there are rational dilemmas. This paper focuses on an often misunderstood and underexplored response to this (and similar) puzzles, the so-called conflicting-ideals view. Drawing on work from defeasible logic, I propose understanding this view as a move away from the default metaepistemological position according to which rationality requirements are strict and governed by a strong, but never explicitly stated logic, toward the more unconventional view, according to which requirements are defeasible and governed by a comparatively weak logic. When understood this way, the response is not committed to dilemmas.", "pred_label": "__label__POS", "pred_score_pos": 0.7249205708503723}
{"content": "Medical students’ perceptions towards learning communication skills: a qualitative study following the 2-year training programme.\nAbstract: Objective: This study aimed to gain an understanding of the perceptions of 4th-year medical students about a training course in communication skills with 'experiential learning' characteristics, completed over the past two years.Methods: Twenty 4th-year medical students were invited to participate in a qualitative study with focus groups. These students were selected randomly, stratifying by gender, from all 4th-year medical students (106) at the Francisco de Vitoria University (Madrid). The students had just completed their communication skills training taught in small groups, with simulated patient interviews and feedback. The focusgroup facilitator used an open-ended discussion guide to explore the students' perceptions. Thematic analysis was used to identify salient themes from these discussions. Results: Sixteen students participated in two focus groups. The discussions revealed two contrasting perceptions: while this learning is considered useful, it nevertheless brings about a great deal of stress, especially regarding student exposure to peers in small-group sessions when interviewing standardised patients, and summative assessment. This generates a range of negative feelings in students that could affect perspective and attitude towards the importance of doctor-patient relationships. Conclusions: Experiential learning is effective in improving students' communication skills. However, these results suggest that use of such strategies requires a strong focus on \"student-centred\" teaching approaches, in order to minimise some sensitive topics that may arise during the learning. Further research is needed to refine these strategies depending on the teaching situation and to identify different ways of implementing these experiential methods.\nUniversal identifier: http://hdl.handle.net10641/2090\nDate: 2019\nCollections MEDICINA [229]", "pred_label": "__label__POS", "pred_score_pos": 0.5810670256614685}
{"content": "Description What is Coluracetam?\nColuracetam is a new racetam-type nootropic believed to be beneficial in enhancing memory, learning, improving vision, and supporting the treatment of anxiety and depression.\nWhat’s Coluracetam Benefits? Improves Memory and Learning Reduces Treatment-Resistant Depression Reduces Anxiety Promotes Neurogenesis Helps with Schizophrenia Enhances Eyesight How To Take Coluracetam?\nRecommended starting dose is 20mg.\nTake it with a choline source. It can be in supplement form (Alpha-GPC. Citicoline), or from foods in your own diet.\nPairing coluracetam with a choline source will both, increase its effect, and prevent an associating headache.\nWhere to Buy Coluracetam in the UAE?\nNootropix offers 30 & 60ct. Coluracetam capsules and tablets. All products are lab-tested and verified for both product purity and identity.\nIn most cases, orders ship within 24 hours for orders placed within Abu Dhabi, Dubai, and the UAE.\nAttention: This product is not intended to diagnose, treat, cure, or prevent any disease. It has not been approved, nor have these statements been evaluated, by the FDA.", "pred_label": "__label__POS", "pred_score_pos": 0.8161898851394653}
{"content": "Bedside microcomputer-derived, minute-to-minute mean arterial pressure (MAP) values during the first 48 hours of life were studied in 100 preterm babies with birth weight less than or equal to 1500 gm. In those babies (n = 72) with no periventricular-intraventricular hemorrhage (PV-IVH) or with grade 1 PV-IVH, the MAP values increased during the study period, with minute-to-minute variation and interval undulation. The MAP values in those with birth weight greater than 1000 gm were higher than in those of lower birth weight. Infants in whom grades 2 to 4 PV-IVH developed (n = 28) had consistently lower MAP values during the study period. Minute-to-minute variability, expressed as the average of the coefficients of variation at 15-minute intervals, did not differ between birth weight groups, nor did they differ between the PV-IVH group and their matched control subjects. However, those with PV-IVH spent a greater percentage of time, with a coefficient of variation greater than or equal to 13% or less than 3%, than their matched control subjects spent (p less than 0.005). This study provides reference data for MAP changes in premature babies. The observed MAP changes in those with PV-IVH lend support to a significant role for MAP alterations in the pathogenesis of PV-IVH.", "pred_label": "__label__POS", "pred_score_pos": 0.830642580986023}
{"content": "Background: Recovery after stroke correlates with non-active (stunned) brain regions, which may persist for years. The current study aimed to evaluate whether increasing the level of dissolved oxygen by Hyperbaric Oxygen Therapy (HBOT) could activate neuroplasticity in patients with chronic neurologic deficiencies due to stroke. Methods and findings: A prospective, randomized, controlled trial including 74 patients (15 were excluded). All participants suffered a stroke 6-36 months prior to inclusion and had at least one motor dysfunction. After inclusion, patients were randomly assigned to \"treated\" or \"cross\" groups. Brain activity was assessed by SPECT imaging; neurologic functions were evaluated by NIHSS, ADL, and life quality. Patients in the treated group were evaluated twice: at baseline and after 40 HBOT sessions. Patients in the cross group were evaluated three times: at baseline, after a 2-month control period of no treatment, and after subsequent 2-months of 40 HBOT sessions. HBOT protocol: Two months of 40 sessions (5 days/week), 90 minutes each, 100% oxygen at 2 ATA. We found that the neurological functions and life quality of all patients in both groups were significantly improved following the HBOT sessions while no improvement was found during the control period of the patients in the cross group. Results of SPECT imaging were well correlated with clinical improvement. Elevated brain activity was detected mostly in regions of live cells (as confirmed by CT) with low activity (based on SPECT) - regions of noticeable discrepancy between anatomy and physiology. Conclusions: The results indicate that HBOT can lead to significant neurological improvements in post stroke patients even at chronic late stages. The observed clinical improvements imply that neuroplasticity can still be activated long after damage onset in regions where there is a brain SPECT/CT (anatomy/physiology) mismatch. Trial registration: ClinicalTrials.gov NCT00715897.", "pred_label": "__label__POS", "pred_score_pos": 0.6761823892593384}
{"content": "The central memory T cell (TCM) model forms a unique HIV-1 latency model based on primary cells that closely resemble in vivo TCM. The virus employed in this model is based on an engineered vector incapable of replication after initial infection. We show that despite this strategy, replication competent viral particles are released into the culture medium due to recombination between overlapping sequences of the env deleted HIV genome that is co-transfected with intact env. This finding emphasizes the need for careful data analysis and interpretation if similar constructs are employed and urges for additional caution during laboratory work.", "pred_label": "__label__POS", "pred_score_pos": 0.9489456415176392}
{"content": "Nowadays, a rotary blood pump can be used as not only for a bridge to transplantation (BTT) but also for a bridge to recovery (BTR) and a destination therapy (DT). In such cases, evaluation of the recovery level of the native heart provides useful infomation to improve the clinical strategy and decide adequate timing for removing of the RBP. In contrast, the indices for cardiac function have been studied. However, most of them do not consider the assistance with the RBP. In this study, we aimed at evaluating whether E\nmax, which is an index for cardiac function based on the pressure-volume relationships, is still valid during assistance with the RBP from an animal experiment. In the acute animal experiment with an adult goat, we measured pressure-volume (P-V) loops while cardiac function was normal, augmented or diminished. The experimental results revealed that there were typical differences in the shapes of P-V loops when the cardiac function was altered, and E max can still be used as an index for the cardiac function even if the assistance with the RBP is ongoing.", "pred_label": "__label__POS", "pred_score_pos": 0.8527837991714478}
{"content": "Sometimes too much focus can lead to tunnel vision. This is bad in the boardroom as well as the cockpit.\nI experienced a mishap early in my flying days that serves as an example. I was preparing for a return trip to southern NJ from Columbus, OH and wanted to avoid the thunderstorms that were predicted to build throughout the day. While committing to avoiding the storms was prudent, spending all that energy on one task left me vulnerable to other hidden dangers.\nThe first sign of trouble occurred at takeoff when I was halfway down the runway. I heard a loud whooshing sound from the right/front passenger door. I hadn’t completely latched the door and, consequently, air came rushing in. In my mind, I was in no imminent danger because the door would not open due to the outside air pressure. I had to make a decision though: turn around/land to the latch the door or continue without delay to avoid the storms.\nI chose to continue\nThough I initially thought the unlatched door was just an annoyance, I learned differently when I entered the clouds. Since clouds are made of moisture vapor droplets, it began to “rain” inside the cockpit!\nYou can catch the full story in an article published in AOPA Pilot Magazine. In short, bad went to worse and I was forced to land in West Virginia. Though the incident was more embarrassing than anything else, it could have easily escalated to a life-threatening situation.\nAs business leaders, we face the same challenges when we get so deep in the weeds that we lose sight of the big picture. The day-to-day can eat us up and leave us vulnerable to what’s really brewing “outside.”\nThere is hope\nI encourage clients to schedule full-day quarterly and annual meetings outside the office to work “on” their businesses. During these meetings, they review their Rock completion for the previous 90 days and set new/fresh Rocks for the upcoming quarter. As they develop a pulse of working on their business every 90 days, they successfully avoid the tunnel vision that can throw them off track.\nStay focused, but don’t ignore latched doors. They may lead you to West Virginia when your destination is New Jersey!\n11710 Plaza America Drive, Suite 2000 Reston, VA 20190\n703.278.CORE (2673)", "pred_label": "__label__POS", "pred_score_pos": 0.6738030314445496}
{"content": "Question How do you handle disruptive behaviors of hallucinations and delusions? Answer\nWith hallucinations, you might notice the patient talking to themselves in a conversational or emotional way. They may laugh, smile or frown for no apparent reason and appear to see something that you can't see yourself in the room. In these situations, you want to ask if they saw or heard something. Ask how they feel about the situation because you're trying to find out if they are distressed by it.\nYou can also briefly discuss the possibility that the experience is a symptom or hallucination. One way I'll ask this question sometimes is, do you ever hear see things that other people don't hear or see? A lady I was seeing said, \"There's something in the room, \"but when I look, I can't see it.\" I asked, \"do you think it's possible that you're experiencing that because of the medication you're on and how sick you are in the hospital\"? The patient stated, \"Yeah, yeah, I know. It's definitely because I'm in the hospital.\" So that is normalizing it and noting, okay, are we all on the same page.\nYou don't want to act shocked or alarmed. It will worsen the situation. You also don't want to tell them it's not real or just casually dismiss it. You don't want to tell them it's not important because this is an expression of their reality at the moment. This is what they're experiencing. So telling them it's not real is not exactly helpful. You don't want to enter a lengthy discussion about the hallucination either. We don't want to dwell on it. A couple of brief questions just to kind of find out what's going on so you can pass this on to the nurse and the medical team is helpful.\nFor patients that are discussing delusions with you, you should listen neutrally. Be calm and respectful to them. You should lead the conversation away from the delusional contact. You don't want to dwell on it. For example, I had a patient with a delusion that he founded the hospital I work in. He would bring it up a lot. So he'd always be like, \"Well, when I founded this hospital.\" You should just move the conversation away from it. You don't argue with them about it but talk about something else. If he or she insists on discussing it you should be very clear with, we're going to talk about something else. We're gonna focus on the thing we're working on right now instead. If they really insist on discussing it with you instead of just mentioning it, you can say you don't know. You can explicitly just acknowledge that's the reality and explain that there's a difference in perception between the two of you. But again, after every time you're making a statement, coming back to let's focus on the thing at hand.\nYou don't want to try to convince or argue someone out of their delusion. Once again, this is a symptom. It's not your role or helpful to have you try to argue with somebody about what's going on. You also don't want to question or discuss the delusion in great detail. For example, back to that patient that was saying, that he founded the hospital you work at. I'm not gonna go state to him that the hospital was founded 100 years ago and that he is thirty-five years old. That's not helpful. We're not getting into a debate about his delusion. It's a symptom of his illness.", "pred_label": "__label__POS", "pred_score_pos": 0.5431890487670898}
{"content": "Function:\nChromium is an essential trace mineral that plays an important role in optimizing insulin function and the regulation of blood glucose levels. Chromium may also be anti-atherogenic and assist in lowering cholesterol. Following food intake, blood glucose levels rise causing insulin to be secreted by the pancreas. Insulin lowers blood glucose levels by increasing the rate at which glucose enters a person’s cells. Chromium is believed to facilitate the attachment of insulin to the cell’s insulin receptors. Studies also indicate that chromium participates in cholesterol metabolism, suggesting a role for this mineral in maintaining normal blood cholesterol levels and preventing atherosclerosis. Chromium also plays a role in nucleic acid synthesis.\nDeficiency Symptoms:\nDue to processing methods that remove most of the naturally occurring chromium from commonly consumed foods, dietary deficiency of chromium is believed to be widespread in the United States. Chromium deficiency may increase the likelihood of insulin resistance, a condition which the cells of the body do not respond to the presence of insulin. Insulin resistance an lead to elevated blood levels of insulin (hyperinsulinemia) and elevated blood levels of glucose, which can ultimately cause heart disease and/or diabetes. Deficiency of chromium is associated with metabolic syndrome. Metabolic syndrome represents a constellation of symptoms, including hyperinsulinemia, high blood pressure, high triglyceride levels, high blood sugar levels, and low HDL cholesterol levels. These symptoms increase one’s risk for heart disease. Low levels of chromium are also associated with an increased risk of coronary artery disease incidence and mortality.\nChromium deficiency correlate with depressed nucleic acid synthesis. Chromium is essential for maintaining the structural stability of proteins and nucelic acids and animal studies have found that this element is also vital for healthy fetal growth and development. Studies on humans have established that premature infants and those with evidence of intrauterine growth retardation have significantly lower chromium status compared to infants born full-term. Others have found that multiparous women have far lower body chromium levels compared to nulliparous women. These findings suggest that chromium is an essential trace element during fetal growth and development.\nRepletion Information:\nIn 2001, the Institute of Medicine at the National academy of Sciences conducted a thorough review of the chromium research can concluded that excessive intake of chromium from foods or supplements is not associated with any adverse effects. As a result, to Tolerable Upper Intake Level (UIL) was established for this mineral. However, people with liver or kidney disease may be more susceptible to adverse effects from excessive intake of chromium, and such individuals are cautioned to avoid taking more than 200 micrograms of chromium supplements per day. There is limited evidence to suggest that long-term chromium picolinate supplementation at levels greater than 200 micrograms per day may also be hazardous to chromosome integrity and should be avoided.", "pred_label": "__label__POS", "pred_score_pos": 0.6411713361740112}
{"content": "JavaScript is disabled for your browser. Some features of this site may not work without it.\nHetzinger S, Pfeiffer M, Dullo W-Chr, Zinke J, Garbe-Schönberg D (2016) A change in coral extension rates and stable isotopes after El Niño-induced coral bleaching and regional stress events. Scientific Reports 6: 32879\nCoral reefs are biologically diverse ecosystems threatened with effective collapse under rapid climate change, in particular by recent increases in ocean temperatures. Coral bleaching has occurred during major El Nino warming events, at times leading to the die-off of entire coral reefs. Here we present records of stable isotopic composition, Sr/Ca ratios and extension rate (1940-2004) in coral aragonite from a northern Venezuelan site, where reefs were strongly impacted by bleaching following the 1997-98 El Nino. We assess the impact of past warming events on coral extension rates and geochemical proxies. A marked decrease in coral (Pseudodiploria strigosa) extension rates coincides with a baseline shift to more negative values in oxygen and carbon isotopic composition after 1997-98, while a neighboring coral (Siderastrea siderea) recovered to pre-bleaching extension rates simultaneously. However, other stressors, besides high temperature, might also have influenced coral physiology and geochemistry. Coastal Venezuelan reefs were exposed to a series of extreme environmental fluctuations since the mid-1990s, i.e. upwelling, extreme rainfall and sediment input from landslides. This work provides important new data on the potential impacts of multiple regional stress events on coral isotopic compositions and raises questions about the long-term influence on coral-based paleoclimate reconstructions.", "pred_label": "__label__POS", "pred_score_pos": 0.9188443422317505}
{"content": "In a world of constant disruption and mounting tension, it has never been more important to be courageous – at home, in workplaces, and in the community. We need people who will challenge the status quo, develop collaborations and partnerships, hold self and others accountable for their actions, and be true to personal purposes and values, despite pressures from multiple directions. And yet there is little data on workplace courage in the world. To develop a better understanding of workplace courage, 366 employees across a range of industries completed a series of questions on 38 specific workplace situations. They were asked to consider how worthwhile the situation is, the risk associated with the situation and how willing they are to act on the situation, reflecting on what workplace courage means to them. Findings suggest that courage involves speaking up, confidence, having difficult conversations, taking on challenge, honest communications, and personal risk. The more that an action is seen as worthwhile, the less risky it seems to be and the more likely people are to act. We consider insights that arise from the data and implications for fostering workplace courage.", "pred_label": "__label__POS", "pred_score_pos": 0.8981342911720276}
{"content": "This design competition is currently accepting votes for the Designer's Choice Award.\nRemember the ID numbers of your 5 favorite designs. You will need them for voting.\nGenius Loci – Deity or spirit of a place\n“The remnants of factories that have survived throughout the Caribbean region serve as examples of considerable architectural achievement and of the islands’ prosperity when ‘sugar was king’. Like fortifications and estate houses, the sugar factories were built by the slave population, and these remains survive as their legacy of toil and skill.” – JUDITH A. TOWLE. Today, erasure of historical traces in the landscape is unbridled due to inadequate legislation and a pervasive apathy towards the merit and value of their restoration. Grenada’s second largest town, Grenville, located on the Atlantic coast, possesses one of the few remaining colonial buildings, now slated for demolition. Adaptive reuse of this once magnificent Georgian landmark reimagines it as host to a new urban centre, activating and infusing purpose into a building left abandoned since it was gutted by fire over a decade ago. Restoring its distinguished brick façade allows it to embrace a new commercial program, yet assert its historical countenance as a scenographic marker throughout the new spaces framed within its walls. At street level, the old eastern façade reaffirms its civic presence. It is porous, inviting pedestrians into a courtyard engaged in a dialogue between contrasting visages of different eras. Growing upward and respectfully set back from the old facade, new interior spaces hover over the ground level parking connecting the two main arteries of the town. Despite Grenville’s clustering of commercial buildings looped around Ben Jones Street and Victoria Street, the town suffers from congestion and lack of a designated centre. Sitting in the low-lying basin of La Baye, the town is predisposed to frequent flooding. As in other coastal Caribbean towns, climate resilience has introduced critical design parameters. The new Grenville commercial centre is conceived as a catalyst for improvement of the town fabric. The site is re-cast as a main attractor for Grenville. Elevating the commercial levels safeguards them from flooding while maximizing onsite parking below. A dynamic, transformative architecture emerges at the interface between the old and new. To offset Grenada’s high energy costs, Green Building Technology is embedded within the design framework, including photovoltaic cells, a solar chimney, a reflection pond to provide passive cooling, Low-E glazing, and a water collection system. At the western entrance on Ben Jones Street, a monolithic stairway with seating tiers and an accessible ramp lead to an elevated public plaza. A stylized solar canopy presents a more contemporary portal, broadcasting progressive new ideals and reinvigoration of a landmark. The plaza offers the public a reprieve and a place to meet away from the crowding at street level. Currently no such space exists within the town. Built on its past foundations, the proposed commercial facility brands its spirit and legacy onto the conscience of the community, as a protected cultural asset. As a small developing state, Grenada relies heavily on tourism. Conservation of its unique sense of place, its history and its environment are paramount to ensure sustainability for a prosperous future.\nView the Listing Sheet PDF\nfor this submission", "pred_label": "__label__POS", "pred_score_pos": 0.5634969472885132}
{"content": "Email Newsletter\nJoin thousands receiving hot new sex related articles, goodies, and great deals.\nSexsomnia refers to sexual behaviors that occur during the non-REM sleep cycle. It is a condition that falls within the parasomnia classification of sleep disorders. Sexsomnia is also known as sleep sex.\nBehaviors associated with sexsomnia include masturbation, fondling, sexual intercourse, as well as sexual assault or rape. Similar to sleepwalkers, sexsomniacs often do not remember their actions after an episode. It is unclear what causes episodes of sexsomnia to occur, but it is thought that triggers such as stress, exhaustion, and the use of drugs or alcohol can contribute to sleep sex. Sexsomnia is often treated with either sedatives or antidepressants.\nIf you're just tipping your toe into the world of BDSM, you may be unsure where to even start when it comes to planning out a scene.\nWe made this quiz to provide you with your next, or first, BDSM scene based on your own tastes and desires!\n$11.99\n$59\n$12", "pred_label": "__label__POS", "pred_score_pos": 0.5042176842689514}
{"content": "Humber’s Bachelor of Digital Communications degree program explores the dynamic media environment and the cultural, social, economic and political implications of digital innovation. Communications studies are becoming recognized as one of the most significant social sciences in the 21st century. Increasingly, worldviews are shaped through messages received from television, film, the internet, social media and a host of media arts, with profound impacts on how the world and the self are viewed. The construction of everyday lives and identities are negotiated through digital media and social networks which influence how we live, the products we produce and consume, and how we connect.\nThis program is rigorous and innovative, developing digital storytellers who are skilled in writing, visual communication, web applications and social media. You will build significant business acumen while working in an environment where creative ideas and methods cross-pollinate. As you gain technical competency, you will collaborate and innovate with peers, faculty and visitors, building personal communication and networking skills. Intensive lectures and labs provide direction and practical experience, sharpening technical skills and stimulating critical discourse, using student work as a starting point. Access to studios and computing spaces enables reflective and collaborative project work. Historical, legal, ethical and theoretical considerations are built into the creative process.", "pred_label": "__label__POS", "pred_score_pos": 0.5287195444107056}
{"content": "This posting was originally posted on the CBRS Alliance blog. You can read the original post here.\nJoin us for an upcoming webinar focusing on how new connectivity technologies can tame some of the communications challenges facing modern healthcare organizations.\nPerhaps no other industry has been revolutionized by technology as much as healthcare.\nMobile devices, wireless access, digitized records, smart sensors, internet of things and a range of other innovations have swept through...\nHealthcare operations are being revolutionized by new communications technology, including mobile devices, video consultation, messaging and smart devices.\nWe’re highlighting an exciting new approach to mobile communications for healthcare enterprises at\nVidyo’s Healthcare Summit in Nashville next week.\nOur Kinetic Telehealth solution empowers clinicians and other healthcare professionals to engage in compliant mobile voice, text and video communications with patients and others.\nFrom a costs standpoint, the healthcare industry is pinched from all sides. Hospitals and other healthcare players are doing their best to keep expenses down, while providing ever-advancing medical care and technology, and all in the face of often dwindling reimbursement rates from health insurers and governments.\nDecember 31, 1969", "pred_label": "__label__POS", "pred_score_pos": 0.6115297079086304}
{"content": "However, the seeds of this crisis go back decades, spanning mayoral administrations and regulatory regimes. The New York City medallion industry began in 1937, when the City Council passed the Haas Act. Designed to address an oversupply of taxis in the city, the Haas Act restricted entry into the taxicab market by limiting the number in the city to 13,595. To enforce this restriction, every taxicab was issued a numbered owners permit — or medallion. What the Haas Act did not do, however, was explicitly prohibit the transfer of these owners’ permits. Unlike other operating permits, owners of taxicab medallions were implicitly free to sell their permits.", "pred_label": "__label__POS", "pred_score_pos": 0.9984532594680786}
{"content": "A uniform circular array of isotropic sensors that stochastically dislocate in three dimensions—The hybrid Cramér-Rao bound of direction-of-arrival estimation Date2019-07 Author\nWong, Kainam Thomas\nMorris, Zakayo Ndiku\nKitavi, Dominic M.\nLin, Tsair-Chuan\nMetadataShow full item record Abstract\nAn array’s constituent sensors could be spatially dislocated from their nominal positions. This paper investigates how such sensor dislocation would degrade a uniform circular array (UCA) of isotropic sensors (like pressure sensors) in their direction-finding precision. This paper analytically derives this direction finding’s hybrid Cram er-Rao bound (HCRB) in a closed form that is expressed explicitly in terms of the sensors’ dislocation parameters. In the open literature on UCA direction finding, this paper is the first to be three-dimensional in modeling the sensors’ dislocation. Perhaps unexpectedly to some readers, sensor dislocation could improve and not necessarily degrade the HCRB; these opposing effects depend on the dislocation variances, the incident source’s arrival angle, and the signal-to-noise power ratio—all analyzed rigorously in this paper. Interesting insights are thereby obtained: (a) The HCRB is enhanced for the impinging source’s polar arrival angle as the sensors become more dislocated along the impinging wavefront due to aperture enlargement over the stochastic dislocation’s probability space. (b) Likewise, the HCRB is improved for the azimuth arrival angle as the sensors become more dislocated on the circular array’s plane, also due to aperture enlargement. (c) In contrast, sensor dislocation along the incident signal’s propagation direction can only worsen the HRCBs due to nuisance-parameter effects in the Fisher information. (d) Sensor dislocation orthogonal to the array plane must degrade the HCRB for the azimuth arrival angle but could improve the HCRB for the polar arrival angle.", "pred_label": "__label__POS", "pred_score_pos": 0.514795184135437}
{"content": "instructional strategies for teaching Social studies\nIn this section, teachers will find practical suggestions for making geography and social studies accessible students who are blind or visually impaired. Included are tips for the classroom, ideas for activities, and techniques to adapt lessons and materials.\nBelow is a list of topics you'll find in this section. Click on a title to jump to a specific topic.\nFamily Connect for Parents of Children with Visual Impairments\nAimed at parents, this page provides a brief overview of the challenges facing teenagers with visual impairment who are studying geography and history.\nInternational Council for Education of People with Visual Impairment (ICEVI)\nSlovenian teacher Roman Brvar outlines considerations for teaching geography to students with a visual impairment, including educational materials and teaching methods.\nRoyal National Institute of Blind People (RNIB)\nRNIB's classroom resources pages contain suggestions for specific subject areas, including Geography\nStaffordshire Learning Net\nStuart Snowdon offers practical\nstrategies for teaching geography to students with visual impairments, including ideas for instructional methods, materials, and mapwork.\nNational Geographic Society\nOrganized by grade level, the topics include the Amazon, Mexico, Gaza, Okavango, Tarantulas, the White House, and Wildlife Refuges.\nOpportunities for learning are abundant outside of the classroom, but field trips and fieldwork will be meaningful to students who are blind or visually impaired only if they're accessible. These resources offer suggestions for preparation, accommodation, and making the most of the time in the field.\nEnglish Heritage\nUsing these practical suggestions will make historical site visits meaningful to students who are blind and visually impaired. Tactile representations, audio recordings, and the use of large print are discussed.\nGeography Discipline Network\nThis guide identifies the challenges faced by students doing fieldwork in geography, and suggests strategies for overcoming them. Included is advice on note taking, handouts, and the use of maps and other graphics.\nNCGE works to enhance the status and quality of geography teaching and learning. The site includes links to resources, publications, and events.", "pred_label": "__label__POS", "pred_score_pos": 0.9594749212265015}
{"content": "The director’s message typically offers a brief reflection of the recent past and hints about the near future. However, as I write this October message, the observation that hindsight is 20/20 looms large. As is true for every one of us, the reality of 2020 contrasts sharply with the ambitious vision I suggested one year ago. This observation led me to question whether clarity is possible when the times appear confusing.\nBelow is a snapshot of four goals I had anticipated the Belin-Blank Center would achieve by this time in 2020.\nAn abundance of opportunities for educators, students, and families. Expansion of commuter programming to 8th graders. Experience of a dynamic in-person summit on the neuroscience of twice-exceptionality. Extensive scholarship related to our comprehensive research agenda.\nDid the confusion caused by the ongoing health, economic, social, and environmental crises obscure those goals?\nNot exactly. I discovered an essential filter through which I now view the future: the “optimism” filter. Through this filter, I can see the unwavering hopefulness and collective energy demonstrated by our very talented faculty and administrative, clerical, and graduate staff. Our professional team never lost sight of the need to stay safe and healthy to continue focusing on our primary aim of nurturing potential and inspiring excellence.\nDid the confusion caused by the ongoing health, economic, social, and environmental crises enhance our focus?\nYes, to some extent. These crises have been, and likely always will be, a part of our reality. The experiences of the past months have made clear that some issues must remain central to the Belin-Blank Center’s vision for our programming, services, and research. We will stay dedicated to addressing them through all aspects of our work.\nAs a Belin-Blank Center staff member for three decades, I can draw upon experience to remain optimistic about the near future. In the coming weeks and months, we will:\nContinue to offer meaningful opportunities for educators, students, and families, thanks to technology; Utilize our decades of online learning experience to create new online elementary, middle, and high school programs; Host a dynamic virtual summit on the neuroscience of twice-exceptionality; Make our scholarship more relevant to the most significant crises facing us today and in the future.\nWe already have many exciting developments on these fronts. This fall alone, we have created an unprecedented\nfour brand-new student programs designed to accommodate learners both during the pandemic and afterward. (Check out the Writers’ Room, the Coders’ Lab, Coding with Python, and Enrichment Expeditions!) In the spring, we will add a host of online student competitions. Keep an eye out for news on Invent Iowa, the Scholastic Art & Writing Awards, and the Junior Science and Humanities Symposium.\nWe have an extensive catalog of online professional learning courses for educators and those seeking a TAG endorsement. Planning for our online Summit on the Neuroscience of Twice-Exceptionality is well underway, and we are looking forward to lively discussions of research and networking opportunities in May.\nThough life remains unpredictable and often confusing, every crisis holds opportunity. We hope you will join us in the new opportunities we are creating for you.", "pred_label": "__label__POS", "pred_score_pos": 0.9293469190597534}
{"content": "What’s in a name? – This is a common adage, indicating that the inherent qualities of a person or thing are unaltered, irrespective of what we may choose to call it. While this is certainly true, it is also true that the words we choose to use in our speech influence our thoughts and perceptions to a big extent. Words can create positive or negative emotions or perceptions in those that we speak them to.", "pred_label": "__label__POS", "pred_score_pos": 0.6639435291290283}
{"content": "SCIENTIFIC REPORTS—The largest collection of footprints from the human fossil record in Africa is described in\nScientific Reports this week. The findings, which further our understanding of human life during the Late Pleistocene period (126,000 to 11,700 years ago), suggest a division of labour in ancient human communities.\nKevin Hatala and colleagues uncovered 408 human footprints in Engare Sero, Tanzania after the site was discovered by members of a nearby Maasai community. The researchers dated the footprints to between 19,100 and 5,760 years ago. Based on their size, the distances between them and their orientations, the authors suggest that 17 tracks of footprints were created by a group of individuals moving together at walking speed in a southwesterly direction. The group was likely made up of 14 adult females, two adult males and one young male. The authors speculate that the females who made the tracks were foraging together and were visited or accompanied by the males, as this behavior is observed in modern hunter-gatherers such as the Ache and Hadza. The findings may indicate a division of labor based on sex in ancient human communities.\nFor an additional six tracks of footprints oriented to the northeast, the authors estimate a broader range of variation in speed, which may suggest that they were not created by a single group traveling together, but by various individuals running and walking at different speeds.\nThe findings provide a snapshot of the movements and group behavior of modern humans living in east Africa during the Late Pleistocene period.\n_______________________________\n_______________________________\n*Article Source: Scientific Reports news release and study report\n_______________________________\nAdvertisement", "pred_label": "__label__POS", "pred_score_pos": 0.5472464561462402}
{"content": "Challenging the status quo bias of any prospect is essential when trying to secure a sale – particularly when the prospect is already committed to a competing supplier. However, if not conducted well, challenging the status quo can have a detrimental effect on the sales outcome.\nSales Process & Methodology\nA well thought out and implemented process in B2B sales is critical to success. B2B sales can be a complex and time-consuming process, involving many stakeholders and high financial stakes.\nA sales methodology puts structure around the process a salesperson uses to do their job. It’s a set of rules for how to approach customers and sell products or services to them.", "pred_label": "__label__POS", "pred_score_pos": 0.6162093877792358}
{"content": "Characters of literature embody their unique personal qualities from elements of their lives. A merging of expectations and their environment, though neither in perfect balance, molds the two Wes Moore’s, Telemachus, and Elie Weisel, and determines their overall identity. Influencing expectations include those others form of them, or those they form for themselves. Living space, living place, stresses of life, and the people they live with are all factors of environment. Through these specific aspects of life, characters become further developed.Outside forces, especially their living environment and expectations thrust upon them, influence the lives of the two Wes’ in The Other Wes Moore. To start, both characters experienced…show more content… His mother needed more money because she was raising both Wes’s and Tony’s kids.” (Moore 145). Military school introduced Wes to an entirely new, highly disciplined living space. Although this environment taught him discipline rather harshly, it shaped Wes through keeping him away from trouble on the streets, while also making him feel rewarded for his hard work. Finally feeling the support he lacked throughout his entire life, military school reignited Wes’ desire to do well. “They made it clear that they cared if I succeeded, and eventually so did I.” (Moore 115). Positive effects spiraled from this environment. Contrarily, the other Wes Moore’s environment negatively influenced him. Without a father-figure, Wes’ role model became his older brother, Tony, who actively participated as a drug dealer. Introducing him to a life filled with crime, Wes’ dependence and utmost respect regarding Tony led him in the wrong direction, and ultimately created his future as a criminal. However, Tony wasn 't the only driving factor in Wes’ joining the game; living in a dangerous neighborhood also added to an environment that pushed him into drugs. Additionally, expectations that characters must uphold also characterize them. Both characters are expected to stay out of trouble. The first Wes Moore masterfully fulfills this duty, becoming quite successful; however, other Wes Moore did not", "pred_label": "__label__POS", "pred_score_pos": 0.5244439840316772}
{"content": "While clothes dryers are designed to make your life easier, they can also become a serious safety hazard if they are not maintained. Each year, more than 15,500 home fires start due to clothes dryers. Knowing how to prevent a fire in your clothes dryer, can help to ensure that your home and family stayRead more", "pred_label": "__label__POS", "pred_score_pos": 0.7569955587387085}
{"content": "What To Expect From A Divorce In Texas\nGoing through a divorce is bound to involve stress, no matter how complex or simple your circumstances. One way to reduce the stress of your upcoming divorce is to understand what to expect from the legal process.\nNikki Hudman, the founding attorney of Law Office of Nikki Hudman, believes in keeping you informed and involved in every aspect of your divorce. As a board certified family law attorney, she does divorce differently. She can help you regain control of your life before, during and after a divorce — and this starts by helping you understand what to expect in a Texas divorce.\nWhat Is The Divorce Process Like In Texas?\nEvery divorce is unique, but there are a few procedures that everyone must follow. To file for a divorce in Texas, you and your spouse must have resided in the state for at least six months and in your county for at least three months.\nThere are two types of divorce:\nUncontested divorce: If you and your partner agree on the major aspects of your divorce, then you can file divorce papers jointly. A judge will sign the final decree. Contested divorce: One spouse files divorce papers and serves a copy to the other spouse. The other spouse has 20 days to file a response.\nAfter a spouse files divorce papers, the state requires a 60-day “cooling off” period before finalizing the divorce. This period is when couples can use collaborative law or work with a mediator to make decisions out of court. If you and your spouse can’t reach an arrangement, then your case will proceed to trial, where a judge will issue a decision for you.\nGuiding You Through Divorce With A Cool Head\nDivorce is rarely pleasant. It is tempting to want to rush the legal process, but it is crucial to take your time. This ensures that you consider every available option, advocate for your best interests with a cool head and complete every step correctly. With years of experience securing favorable divorce outcomes, Law Office of Nikki Hudman is the law firm to assist you.\nLearn More About The Divorce Process\nYou can contact the Law Office of Nikki Hudman to schedule a consultation. There, you can ask your questions to Ms. Hudman in person. To schedule, call (512) 827-8529 or send us an email.", "pred_label": "__label__POS", "pred_score_pos": 0.5355591773986816}
{"content": "Controversial report on air pollution and asthma\nA report by the Department of Health's Committee on the Medical Effects of Air Pollutants (COMEAP) has concluded that outdoor air pollution does not cause asthma.\n1 But its controversial conclusion that pollution triggers clinically significant effects in only a small proportion of asthmatics does not agree with the daily experience of many sufferers, and may reflect under-reporting of their symptoms.", "pred_label": "__label__POS", "pred_score_pos": 0.9649379253387451}
{"content": "Released10/24/2017 List the primary components of strategy. Set and communicate strategic priorities. Define culture. Evaluate and run ideas in a prioritization process. Identify how to measure progress and performance. Explain how to maintain focus and eliminate distractions. Describe key processes for building a culture of strategy execution. Skill Level\nAdvanced Duration Views\n- A longtime colleague of mine always says, \"Thoughts are nice, but actions matter.\" His words perfectly describe what it takes to successfully execute a strategy. I'm Mike Figliuolo, Managing Director of thoughtLEADERS. I've worked with companies large and small on creating a strategy, and making it happen. The most successful companies I've seen are the ones that build a culture of strategy execution. In this course, I'll explain what it takes to build such a culture.\nWe'll review the links between strategy, culture and execution. We'll talk about the processes to allocate resources, set goals, and define and award incentives. Then we'll look at executing the plan, measuring progress, celebrating success, and developing the talent you need to make your plan a reality. We'll also look at how to overcome the challenges that arise when you're executing your strategy.\nIt takes deliberate effort to create a company culture focused on executing a strategy. So let's get started.", "pred_label": "__label__POS", "pred_score_pos": 0.7245384454727173}
{"content": "Abstract\nPolicy makers are increasingly investing in programs focused on identifying and addressing the nonmedical needs of high-utilizing Medicaid beneficiaries, yet little is known about these programs' implementation. This study provides an overview of early progress in and strategies used to implement California's Whole Person Care (WPC) Pilot Program, a $3 billion Medicaid Section 1115(a) waiver demonstration project focused on improving the integrated delivery of health, behavioral health, and social services for Medicaid beneficiaries who use acute and costly services in multiple service sectors. WPC pilots reported significant progress in developing partnerships, data-sharing infrastructure, and services needed to coordinate care for identified patient populations. We also identified major barriers to WPC implementation, such as difficulty identifying and engaging eligible beneficiaries and the lack of affordable housing. Our findings offer insights to leaders and policy makers interested in testing new approaches for improving the health and well-being of medically and socially complex patients.", "pred_label": "__label__POS", "pred_score_pos": 0.8255083560943604}
{"content": "OrSense, a developer of solutions for non-invasive measurements of various blood parameters, announced that it has received the US Food and Drug Administration clearance for its NBM-200MP, noninvasive hemoglobin (Hb) and pulse oximetry monitor.\nNBM-200MP belongs to OrSense’s NBM-200 family of products, for the noninvasive measurement of Hb levels, enabling monitoring of anemia and hemorrhage.\nCurrently, Hb measurements require collection of blood samples, rendering existing testing methods invasive, painful, time consuming and labor intensive.\nOrSense’s systems offer a unique, breakthrough, non-invasive solution for accurate Hb measurements and hold the potential for improving anemia detection and monitoring by eliminating pain, reducing infection risk and enabling swift Hb level analysis.\nIn addition, noninvasive Hb monitoring offers the possibility of continuous Hb measurement, which can be critical when monitoring bleeding in acute conditions, such as during surgery or childbirth.\nThe NBM-200 systems are compatible with a variety of clinical environments, including hospitals, outpatient clinics and mobile health, and are used for various applications such as primary care, public screening, women’s health and homecare.\nOrSense CEO Lior Maayan noted hemoglobin levels are a critical parameter in practically every aspect of medical care – in the chronically ill, women’s health, during child development, in the operating room and intensive care wards, and during routine checkups in outpatient clinics.\n\"Although over 400 million Hb lab tests are performed annually in the U.S. alone, this important blood test remains costly, time consuming, invasive and intermittent. Our noninvasive hemoglobin monitor offers a true revolution in the management of both acute and chronic anemia.\n\"We are very excited that soon after receiving China FDA approval and in addition to the CE Mark, our hemoglobin and oximetry monitor has now received regulatory recognition in the U.S., which marks the first and important step towards bringing OrSense’s solution to the U.S. market for the benefit of patients in the U.S. and worldwide,\" Maayan added.", "pred_label": "__label__POS", "pred_score_pos": 0.5278953909873962}
{"content": "Title Date of Degree\n9-2020\nDocument Type\nDissertation\nDegree Name\nPh.D.\nProgram\nAnthropology\nAdvisor\nJessica Rothman\nCommittee Members\nLarissa Swedell\nStephanie Levy\nAndres Gomez\nSubject Categories\nBehavior and Ethology | Biological and Physical Anthropology | Comparative Nutrition | Molecular, Genetic, and Biochemical Nutrition | Other Ecology and Evolutionary Biology | Other Genetics and Genomics | Other Nutrition | Zoology\nKeywords\nmicrobiome, ecology, nutritional ecology, development, life history, metabolome, diet-microbe\nAbstract\nIn species who consume folivorous diets, immature individuals must contend with the challenges of extracting nutrients from fibrous foods before dietary adaptations and strategies are fully developed. Additionally, immatures have distinct nutritional needs to support their stage-specific metabolic and biophysiological requirements. To meet these stage-specific needs, while constrained by underdeveloped feeding strategies and digestive capacities, immatures may adopt distinct diets better suited to their specific developmental context. However, where dietary modification is constrained by low dietary diversity or landscape homogeneity, it is unclear how immature individuals compensate through alternative strategies. In turn, little is known about the nutritional and life history implications of restrictions in alternative foraging strategies.\nThis dissertation is divided into three main studies. Firstly, a comprehensive literature review examines the theoretical framework and provides context for the importance and relevance of this topic to the broader study of life history patterning and developmental outcomes. Following this, the diet of mountain gorillas across development is characterized through a combination of four hour focal follows and nutritional biochemical analysis of consumed food items. The results of this study suggest that mountain gorillas self-select their diets to age- and stage-specific nutrient targets, occupying unique nutritional niches within the species’ overall nutritional landscape. To meet these age-specific nutritional needs within their relatively constrained ecological environment, immature mountain gorillas engage in three principle behavioral strategies: 1) differential reliance on food items, including increased consumption of highly digestibly foods as well as self-selection of a balance of nutrients higher in non-protein energy intake relative to protein intake, 2) compensatory foraging and increased overall foraging effort to compensate for biophysiological limitations (i.e. gut size) and behavioral limitations (feeding/foraging competency), and 3) extended use of mother’s milk as a nutritional ‘buffer’ during periods of preferred food scarcity.\nNext, this dissertation considers the one of the most complex and dynamic systems involved in the regulation and utilization of nutrients: the gastrointestinal microbiome. The gastrointestinal microbiome is first characterized using a large library of mountain gorilla samples, spanning all members of three social groups. This characterization confirms previous work on the microbiome of mountain gorillas, and further establishes that the microbiome of mountain gorillas is relatively aseasonal, but can be differentiated based on age-class. Contrary to expectations of diversity, the infant mountain gorilla microbiome is broadly less diverse than those of juvenile and adult individuals, with higher abundance of key hydrogenotrophic taxa and sulfate-reducing bacteria. These taxa may play a role in preventing hydrogen accumulation in the gut during development. Additionally, this study shows that there are differences in the abundance of major phyletic groups (specifically,\nActinobacteria, Firmicutes, and Bacteroidetes), suggesting that immature individuals may house microbiomes with greater capacity for energy harvest, potentially as an adaptation to maximize nutrient availability during periods of growth and development where individuals are sensitive to environmental perturbation and dietary shortfalls.\nLastly, this dissertation considers the dietary metabolome of mountain gorillas through characterization of the fecal metabolome, in a pivotal step to bridge the gap between observed diet/nutrient intake and individuals’ capacity to use ingested nutrients (including through microbiome-mediated nutrient pathways). Mountain gorillas demonstrate distinct metabolomes throughout development, especially with respect to the relative concentration of lipid and lipid-derived molecules and organic acids/phenolic compounds and their derivatives. Additionally, this study explicitly considered the potential influence of observed diet and nutrient intake as drivers of differentiation among age groups; it is found that protein intake is a primary driver of infant microbiome differentiation, and non-digestible fibers are a primary driver in differentiating both the adult microbiome and metabolome.\nThrough these studies, this dissertation provides the first comprehensive examination of nutritional ontogeny through a multi-layered ecological approach, by examining these complex relationships in immature mountain gorillas (\nGorilla beringei). This dissertation significantly contributes to our understanding of nutritional ontogeny and compensatory nutritional strategies among great apes living at the extreme end of their known ecologies, and, in turn, provides a lens towards the potential evolutionary basis of these behaviors and adaptations. Recommended Citation\nCancelliere, Emma C., \"Dietary Development and Nutritional Ontogeny in\nGorilla beringei : A Multi-layered, -Omics Approach\" (2020). CUNY Academic Works. https://academicworks.cuny.edu/gc_etds/4103\nThis work is embargoed and will be available for download on\nFriday, September 30, 2022 Graduate Center users: To read this work, log in to your GC ILL account and place a thesis request. Non-GC Users: See the GC’s lending policies to learn more. Included in\nBehavior and Ethology Commons, Biological and Physical Anthropology Commons, Comparative Nutrition Commons, Molecular, Genetic, and Biochemical Nutrition Commons, Other Ecology and Evolutionary Biology Commons, Other Genetics and Genomics Commons, Other Nutrition Commons, Zoology Commons", "pred_label": "__label__POS", "pred_score_pos": 0.6197969317436218}
{"content": "We guarantee you a high-quality multifaceted approach. Our reliable and tested workflows and specialist domain knowledge combine with in-depth knowledge of your businesses provides you best client experience. We maintain accounts, review them regularly and prepare management reports in accordance with the accounting rules to avoid adjustments during audits. We can guide on better insights into your business while making it compliant.\nTechnological developments have changed methods for carrying out tasks. Through information technology, accounting scope has increased from mere recording to evaluating and interpreting, which has given rise to target-based accounting. We use all sort of available technology such as accounting software, business advancements software, data analysis tools and support applications.\nAccurately securing your data is most critical aspect of our services. We have implemented multi facet security measures to protect data from physical and cyber threats. Our physical security measures include biometric door locks, security personnel, alarm systems, video surveillance, user access passwords encryption and group policies on a network. Moreover firewall, anti-virus software, encryption for archives helps in block spam, malware, spyware, and intrusions.", "pred_label": "__label__POS", "pred_score_pos": 0.9645978808403015}
{"content": "Abstract\nEighty-three women with acute icteric hepatitis during pregnancy were followed for evidence of viral transmission to their infants. Six women had acute hepatitis A as diagnosed by appearance of anti-HAV during convalescence. Except for passively acquired antibodies which were present at birth, anti-HAV did not appear in these infants, and there was no clinical or biochemical evidence for hepatitis during follow-up. Sixty-five pregnant women had acute hepatitis B during pregnancy or in the immediate postpartum period. Transmission to infants often occurred when both maternal HB\nsAg and HB eAg were positive at delivery or postpartum. A majority of these infants never developed jaundice, have remained persistently HB sAg-positive, and have had periodic serum ALT elevations during follow-up. Twelve women had acute non-A, non-B hepatitis during pregnancy. Infants born to 6 of these women near term had transient elevations of serum ALT values at 4-8 wk of age, suggesting maternal transmissibility of the non-A, non-B viral agent. ASJC Scopus subject areas Hepatology Gastroenterology", "pred_label": "__label__POS", "pred_score_pos": 0.9860086441040039}
{"content": "A dishwashing machine is a mechanical device for cleaning dishware and cutlery. Unlike manual dishwashing, which relies largely on physical scrubbing to remove soiling, the mechanical dishwasher cleans by spraying hot water, typically between 45 and 75 °C (110 and 170 °F), at the dishes, with lower temperatures used for delicate items.\nA mix of water and dishwasher detergent is pumped to one or more rotating spray arms, which blast the dishes with the cleaning mixture. Once the wash is finished, the water is drained, more hot water is pumped in and a rinse cycle begins. After the rinse cycle finishes and the water is drained, the dishes are dried using one of several drying methods. Typically a rinse aid is used to eliminate water spots for streak-free dishes and glassware resulting from hard water or other reasons.\nIn addition to domestic units, industrial dishwashers are available for use in commercial establishments such as hotels and restaurants, where a large number of dishes must be cleaned. Washing is conducted with temperatures of 65–71 °C (149–160 °F) and sanitation is achieved by either the use of a booster heater that will provide a 82 °C (180 °F) “final rinse” temperature or through the use of a chemical sanitizer.", "pred_label": "__label__POS", "pred_score_pos": 0.8049241900444031}
{"content": "Physical therapy is a safe, effective, and non-invasive treatment option that is designed to relieve pain resulting from a wide range of musculoskeletal conditions, sports injuries, workplace injuries, and more. Patients typically see a physical therapist to help manage chronic pain symptoms and prevent future injury, and regular appointments with a physical therapist are ideal", "pred_label": "__label__POS", "pred_score_pos": 0.9391698837280273}
{"content": "01.4.\nDescribe your organisation’s investment principles and overall investment strategy, interpretation of fiduciary (or equivalent) duties,and how they consider ESG factors and real economy impact.\nPoste Vita’s Responsible Investment (RI) policy reflects Gruppo Poste Italiane’s Sustainability Plan by incorporating ESG considerations in the scope of insurance and financial activities. The RI policy aims to deliver positive economic, environmental and social impacts, to establish a sound communication with the Company’s stakeholders and to adhere to international principles and guidelines. Poste Vita’s RI policy is conveyed to external managers who are required to observe at least the main guidelines. Poste Vita’s incorporation of ESG starts with the ESG assessment of issuers both governmental and corporate in the Company’s portfolio, which is built by reflecting also an exclusion criteria. The Investment Committee is responsible for ESG assessments, which pair internal analysis with externally provided information. The process continues with regular monitoring of the issuer’s ESG profile. The Company’s RI policy provides also with guidelines for engagement and proxy voting and guidelines for specific sensitive sectors.\n01.5.\nProvide a brief description of the key elements, any variations or exceptions to your investment policy that covers your responsible investment approach. [Optional]\nPoste Vita’s investment policy has adjusted in accordance with the introduction of RI objectives and strives to carry out the investment activities and to pursue the traditional financial objectives incorporating ESG. On the one hand, this overarching goal is witnessed by one remarkable achievement that Poste Vita obtained for the reporting year: it was awarded by Capital Finance International as “Best Pension Fund Governance” for combining ESG principles with the performance required by investors. On the other, Poste Vita is committed to enhance the RI approach in managing its portfolio: this goal reflects on an investment strategy that aims to improve the ESG profile of the portfolio, considering the ESG score of all the included assets. At the end of this reporting year, Poste Vita managed to strengthen the ESG score of its portfolio: the weighted average score of the portfolios assessed was 51/100 in relation to the assets managed by the Poste Vita for corporate issuers and 75/100 in relation to governmental issuers. This result was higher than the ESG score of a benchmark of Ishares MSCI World ETF that was 39/100 at the same date.", "pred_label": "__label__POS", "pred_score_pos": 0.7245482206344604}
{"content": "Title\nSynthesis and Optical Properties of Colloidal PbS Nanosheets\nDate of Award\n2019\nDocument Type\nDissertation\nDegree Name\nDoctor of Philosophy (Ph.D.)\nDepartment\nPhotochemical Sciences\nFirst Advisor\nLiangfeng Sun (Advisor)\nSecond Advisor\nHong Lu (Committee Member)\nThird Advisor\nMikhail Zamkov (Committee Member)\nFourth Advisor\nMichael Zickar (Other)\nAbstract\nColloidal semiconductor nanocrystals are emerging materials for next-generation optoelectronic devices including solar cells and light-emitting diodes (LEDs). Colloidal quantum dots have been developed in the past decades to make solar cells and LEDs with decent efficiencies. However, their performances are limited by low conductivity. To address this problem, two-dimensional nanosheets (also known as nanoplatelets, quantum-belts or nanoribbons) have been developed recently. They have a much higher conductivity than quantum-dot films and tunable optical properties. The new method is developed for the synthesis of colloidal PbS nanosheets with a 100% success rate. We confirmed that residual acetate in the reaction mixture influence for the formation of colloidal nanosheets. Therefore, we have introduced an acetate-free method. The energy gap of the nanosheet is mainly determined by its thickness while the lateral size of the nanosheet has a significant effect on its conductivity, electronic coupling with other materials and the rate of light emission. Therefore, tuning the lateral size of the nanosheet is critical for its application in functional devices. Our work has addressed the challenge of tuning the lateral size of colloidal PbS nanosheets by changing reaction parameters, reducing the Pb to S molar ratio, using long-chain chloroalkane and changing the concentration of chloroalkane. Nanosheets with a small lateral size called nanoplatelets to show a narrow light-emission linewidth around 70 mev and an exciton peak. The platelets have a square shape with a typical width and length 20 nm. The exciton binding energy derived from the absorption spectrum is about 25 meV. Efficient electron transfer from photoexcited electrons from colloidal PbS nanosheets to TiO2 nanoparticles is demonstrated. This transfer occurred faster than compared to quantum dots. This will be more useful for fabricating future solar cell devices.\nRecommended Citation\nPremathilaka, Shashini M., \"Synthesis and Optical Properties of Colloidal PbS Nanosheets\" (2019).\nPhotochemical Sciences Ph.D. Dissertations. 107. https://scholarworks.bgsu.edu/photo_chem_diss/107", "pred_label": "__label__POS", "pred_score_pos": 0.5548102855682373}
{"content": "Abstract\nWhen dietary carbohydrate is unavailable, glucose required to support metabolism in vital tissues is generated via gluconeogenesis in the liver. Expression of phosphoenolpyruvate carboxykinase (PEPCK), commonly considered the control point for liver gluconeogenesis, is normally regulated by circulating hormones to match systemic glucose demand. However, this regulation fails in diabetes. Because other molecular and metabolic factors can also influence gluconeogenesis, the explicit role of PEPCK protein content in the control of gluconeogenesis was unclear. In this study, metabolic control of liver gluconeogenesis was quantified in groups of mice with varying PEPCK protein content. Surprisingly, livers with a 90% reduction in PEPCK content showed only a ∼40% reduction in gluconeogenic flux, indicating a lower than expected capacity for PEPCK protein content to control gluconeogenesis. However, PEPCK flux correlated tightly with TCA cycle activity, suggesting that under some conditions in mice, PEPCK expression must coordinate with hepatic energy metabolism to control gluconeogenesis.\nKeywords HUMDISEASE ASJC Scopus subject areas Physiology Molecular Biology Cell Biology", "pred_label": "__label__POS", "pred_score_pos": 0.8719081878662109}
{"content": "By Leah M. Hamilton\nMany clients have asked whether they can offer skip-a-payment programs for their consumers with consumer mortgage loans by simply executing a modification to extend the term and noting the month(s) to be skipped. The simple answer is YES! If you offer a skip-a-payment program for any of your customers, consumer or commercial, you may do this by way of a modification or amendment to your current agreement. However, if the loan is secured by a building or mobile home and any personal property securing the loan, then a flood determination is triggered when you extend the term of the loan. If you are keeping the same term and adding the deferred payments to the final payment, the flood determination is not triggered.\nUnder the flood rules, any time you make, increase, renew or extend a loan where the building, mobile home or personal property securing that loan, you must determine whether or not such collateral is in a flood zone. Institutions may rely on an existing flood determination provided that:\nThe current flood determination is less than 7 years old; No map changes; and Current flood determination was completed on the then-current flood determination form.\nIf you rely on a prior determination, it is best practice to make a copy of it, list the three requirements with check marks (provided no changes) indicating you verified each of them, and then date and initial it. Lastly, attach it to the Amendment to the note and place in the file so no one has to later search for it. Alternatively, you may be able to have the current one re-certified at a minimal cost – and again, attach it to the Amendment.\nRemember also that an extension is a contractual amendment requiring signatures of both parties (borrower and institution).\nThis type of modification to solely defer the payments short term and extend the loan term does not trigger any new disclosures, including TRID disclosures.\nInteragency Statement on Loan Modifications and Reporting for Financial Institutions Working with Customers Affected by the Coronavirus\nThe federal financial regulatory agencies and state banking regulators (the “Agencies”) have also issued an interagency statement encouraging financial institutions to work constructively with borrowers affected by COVID-19 and providing additional information regarding loan modifications. The\nAgencies encourage financial institutions to work with borrowers and will not criticize institutions for doing so in a safe and sound manner. Additionally, they have stated that they will not automatically categorize loan modifications as troubled debt restructurings (TDRs) – reminding reminds institutions that not all modifications of loan terms result in a TDR. The joint statement also provides supervisory views on past-due and nonaccrual regulatory reporting of loan modification programs. Short-term modifications that are made in good faith in response to COVID-19 to borrowers who were current prior to any such relief are not TDRs. Such short-term modifications may include – for example, six (6) months of payment deferrals, waiver of fees, term extensions or other alternative delays in payment that are insignificant.\nThe agencies view prudent loan modification programs offered to financial institution customers affected by COVID-19 as positive and proactive actions that can manage or mitigate adverse impacts on borrowers, and lead to improved loan performance and reduced credit risk. Regardless of whether modifications are considered TDRs or are adversely classified, agency examiners will not criticize prudent efforts to modify terms on existing loans for affected customers.", "pred_label": "__label__POS", "pred_score_pos": 0.6908975839614868}
{"content": "The Supreme Court rules that the Forest Service can approve natural gas pipelines crossing the Appalachian Trail.\nDespite guidance from the Supreme Court, the future of water regulation remains uncertain.\nCongressional intent and clear statutory text promote common-sense enforcement of federal water regulations.\nA proposed rule aims to facilitate economic growth at the expense of federal environmental reviews.\nEPA’s proposed relaxation of a rule restricting water pollution from coal plants generates controversy.\nCertain communities may face disproportionate harms in the wake of natural disasters.\nGovernment leaders must take swift action to mitigate the risks of wildfire disasters.\nThe judicial system may need to adapt to allow climate change cases to be heard in court.\nDemocratic primary candidates are competing to define the scale and scope of climate action.\nScholars offer suggestions for how regulation can reduce disparities in exposure to environmental problems.\nThe lack of regulation on animals’ greenhouse gas emissions opens the door for climate change litigation.\nScholar argues for promotion of environmentally conscious plant-based diets through regulation.", "pred_label": "__label__POS", "pred_score_pos": 0.9384730458259583}
{"content": "This chapter proceeds as follows. We first present Individual Development Accounts (IDA) and American Dream Demonstration (ADD), review relevant saving theory, and discuss current asset-subsidization policy. We then discuss evidence from ADD on whether the poor can save in IDAs, how IDAs work, where deposits come from, who saves in IDAs, and what IDAs cost. The final section summarizes the main results.", "pred_label": "__label__POS", "pred_score_pos": 0.9935672879219055}
{"content": "DOI: ABSTRACT\nA semiautomated solid-phase immunofluorescence apparatus (FIAX; International Diagnostic Technology, Santa Clara, Calif.) was utilized to develop a rapid method for detection of antibody to Legionella pneumophila. The sera from guinea pigs immunized with a mixture of killed L. pneumophila and Freund complete adjuvant displayed markedly enhanced antibody activity as measured by FIAX when compared with that obtained from adjuvant-injected or unimmunized animals. A correlation was observed between FIAX net fluorescence units and microagglutination titers of serum samples obtained from immunized animals. Within-run and between-run coefficients of variation performed on selected immune serum samples were low. These results demonstrated that the FIAX method could readily and reproducibly detect Legionella-specific antibodies in the sera of actively immunized animals and suggest the possibility of a broader application of FIAX in the serological detection of exposure to L. pneumophila antigen.", "pred_label": "__label__POS", "pred_score_pos": 0.604953944683075}
{"content": "Type:\nVenue: Date:\nThe exact mechanisms that govern the visual identification of complex words (e.g., build-er) are not entirely clear. In particular, it is not obvious why the system would identify (pseudo–)morphemes in words that only have an appearance of morphological complexity (e.g., corn–er, iron–y). One hypothesis is that this phenomenon is driven by letter co–occurrence regularity - morphemes are also recurrent clusters of letters. To test this hypothesis, we assessed masked priming as induced by morphologically structured (e.g., bulb-er) and non-morphologically structured nonwords whose endings were either as frequent (e.g., bulb-le) or less frequent (e.g., bulb-og) than suffixes. We observed equivalent facilitation by the three prime types, suggesting that neither the frequency nor the morphological status of word endings affects masked morphological priming with nonwords. Since this challenges the pattern of results typically observed with word primes, we ran a second experiment where morphological (bulb-er) or non-morphological (bulb-og) nonword primes were compared with transparent derivations (deal-er), pseudo-derived words (corn-er) and orthographic controls (dial-og). The data show a graded pattern of results, with maximal facilitation for transparent primes and no priming for orthographic controls; nonword primes elicited comparable facilitation again, regardless of their morphological status.", "pred_label": "__label__POS", "pred_score_pos": 0.9959537386894226}
{"content": "About\nProgress in Whole Genome Sequencing (WGS) has had a dramatic impact on bacterial epidemiology. It has become possible to reconstruct outbreaks and epidemics in unprecedented detail. WGS also allows linking genotypes to phenotypes and has been surprisingly effective in the context of diagnosing Anti-Microbial Resistance (AMR), with AMR profiles inferred from sequence data being increasingly more accurate and cost-effective than those obtained through classical microbiology. In the first part of the talk, I will illustrate the progress in the field with some recent examples on MRSAs and Mycobacterium tuberculosis. What is less widely acknowledged is that such successes are largely limited to “clonal” organisms such as MRSA and Mycobacteria. In the second part of the talk I will discuss some of the conceptual and computational challenges that lie ahead before we can hope to replicate the successes in the genetic epidemiology of “clonal” bacteria to microbes with extensive recombination, large accessory genomes and resistance determinants situated on plasmids.\nRegistration\nApply here", "pred_label": "__label__POS", "pred_score_pos": 0.6475716829299927}
{"content": "A new report: the 'Impact of IIoT in the Global Water & Wastewater Industry', launched by Research and Markets finds that water and wastewater utilities across the globe are increasingly exploring digital solutions to improve their resilience, and economical and environmental sustainability, which have been impacted by factors like water stress, pollution, and climate change.\nDigitalization through Industrial Internet of Things (IIoT) based smart solutions has emerged as the key solution to tackle various challenges posed by the above factors. Digital transformation (DT) includes the installation and implementation of the following products/solutions: Smart design & engineering, Data collection through IIoT sensors, Smart communication network, Data analytics and Data intelligence.\nAll these are effectively combined to create a smart water grid. Smart analytics platforms are now increasingly being adopted by W&WW utilities for their ability to improve efficiency, comply with regulations, positively impact customer value & service, and improve sustainability of the infrastructure.\nCircular economy has now become a more achievable goal through IIoT-based DT. Water utilities are now exploring new business models such as Software-as-a-Service (SaaS), Data-as-a-Service (DaaS), and Equipment-as-a-Service (EaaS) which have faster return on investment (ROI) and allow for an even placement of investment risks which in turn eases the burden on customers. Research Scope\nThis study estimates that the smart water grid market will reach $20 billion by 2020 and provides market forecast for key smart solution segments such as the Smart NRW leak management solution market, Smart water meters market and Smart online water sensors market, all of which form the core of smart solutions. The study aims to simplify concepts such as IIoT and their applicability as a DT tool in the W&WW industry.\nThis research presents key challenges faced by W&WW utilities, the W&WW network, customer demand management, and W&WW treatment facilities and highlights how IIoT-based smart solutions could be used to tackle these key challenges. It also encompasses cases studies which highlight successful implementation of DT solutions and their benefits. Additionally, the study provides insights on the future of IIoT-based DT solutions, growth opportunities for companies to action, strategies to implement DT, and strategic imperatives crucial for success.\nKey Issues Addressed How can IIoT add value to an existing process? What are the current challenges faced by utilities across the W&WW industry and how IIoT tackles these challenges? How can IIoT accelerate the push toward smart water grids? What is the market size of key smart solutions? Who are the incumbent participants in the IIoT market, and what are they focusing on? Key Topics Covered: 1. Executive Summary Key Findings DT Framework for a Water Utility The Core Elements of DT Digital Water Innovation Hotspots Key Segments of a Smart Water Grid Global Smart Water Grid Market - Market Landscape of Key Segments Key Factors Driving DT Research Scope Key Questions This Research Will Answer 2. Industrial Internet of Things (IIoT) in Water & Wastewater Industry - An Introduction IIoT Fundamentals - What is a Smart Water Grid? IIoT Fundamentals - Sensors and their Application in IIoT IIoT Fundamentals - Water Asset Management Features IIoT Fundamentals - Data-/Software-as-a-service (DaaS/SaaS) 3. Industrial Internet of Things - Water & Wastewater Utilities Key Challenges Faced by Water & Wastewater Utilities How IIoT-based Smart Solutions Improve the Sustainability of Water & Wastewater Utilities Case Study - Asset Management in Water Utilities Enabled by AI Case Study - Big Data and Data Analytics for Water Utilities Case Study - Digital Twin Solutions for Water Utilities 4. Industrial Internet of Things - Water & Wastewater Networks Key Challenges in Water & Wastewater Networks How Smart IIoT Solutions Can Tackle NRW Loss and Improve Energy Efficiency in a Water & Wastewater Network? Revenue Forecast - Smart NRW Leak Management Solutions Market Revenue Forecast Discussion Case Study - Satellite-based Leak Detection Case Study - Smart Pressure Management & Pump Controller Case Study - Smart Acoustic Sensors for Continual Leak Monitoring in Water Networks Case Study - Smart Leak Detection and Pipe Condition Assessment Device for Wastewater Networks 5. Industrial Internet of Things - Customer Demand Management Key Challenges Faced in Customer Demand Management DT through Smart Water Metering LPWAN Communication Technologies and their Potential in Smart Water Metering Unit Shipment and Revenue Forecast - Smart Water Meters Market Revenue Forecast Discussion Case Study - Smart Water Metering Enabled by Advanced Communication Network and Analytics Improves Customer Service Case Study - Smart Water Meter Enables Reduction in NRW 6. Industrial Internet of Things - Water & Wastewater Treatment Key Challenges Faced in a Water & Wastewater Treatment Facility Smart Online Water Sensors and their Impact on Process Efficiency Revenue Forecast - Smart Online Water Sensors Market Revenue Forecast Discussion Case Study - Smart Online Sensors for Intelligent Process Control Case Study - Water & Wastewater Treatment System Automation through AI Case Study - Smart Analytics for Optimized Operation of a Decentralized Wastewater Treatment Facility 7. Industrial Internet of Things - Market Strategy & Analysis What Should be the IIoT-based DT Approach Strategy for Water Utilities? Future of DT in the Water & Wastewater Industry Disruptive Innovations in the Water Industry - Data Analytics Platforms & AI 8. Market Participant Profile Participant Profile - Xylem Participant Profile - ABB Participant Profile - Veolia 9. Growth Opportunities and Companies to Action Growth Opportunity 1 - Value-add Services Growth Opportunity 2 - Partnerships/M&A Strategic Imperatives for Success and Growth", "pred_label": "__label__POS", "pred_score_pos": 0.5782255530357361}
{"content": "CEMEX signed the agreement with Carbon Upcycling, a leading company in the development of nanomaterials derived from the use of CO2 for industrial use, through its corporate venture capital unit, CEMEX Ventures.\nWhile CEMEX uses approximately 3 million tons of industrial residue each year, as additions to cement and concrete, a large portion of industrial waste produced annually cannot be recycled due to its low reactivity. Large quantities of residue or by-products are deposited in landfills and dumpsites, creating significant economic, environmental, and social costs. This initiative seeks to increase industrial residue's reactivity property, allowing more availability of additions with cementitious qualities. With this venture, CEMEX expects to double its current use of industrial residue to consume annually 6 million tons by 2030, thereby reducing its carbon footprint significantly. Carbon Upcycling technology transforms residues such as fly ash and slag, making them more reactive and increasing their cementitious properties. The use of CO2 previously captured, combined with a physical transformation of the material during the process, generates a new addition for the cement that allows the production of concrete with a low environmental footprint. The improvement in the cementitious capacity of materials achieved by the Carbon Upcycling technology will expand the range of sources that can be used to reduce the amount of clinker needed in cement production and the amount of cement required in concrete. The agreement will begin with a coordinated analysis between CEMEX and Carbon Upcycling and its implementation on an industrial scale. The know-how and experience in materials science of CEMEX's Global R&D, in addition to Carbon Upcycling's innovative process, would generate synergies that accelerate the development and industrialization of the technology. CEMEX and Carbon Upcycling anticipate initial results from this joint research and development effort by mid-2021. \"This agreement with Carbon Upcycling is yet another example of our determination to deliver net-zero CO2 concrete products globally by 2050,\" said Gonzalo Galindo, Head of CEMEX Ventures. \"Our roadmap to achieve this global ambition involves continuing to innovate our technology internally while, at the same time, continuing to seek complementary innovation outside of CEMEX through investments in startups, consortia, and high-value collaboration agreements such as the one reached with Carbon Upcycling.\" \"We're thrilled to be partnering with CEMEX Ventures on this initiative and working with CEMEX to achieve their net-zero CO2 commitment,\" said Apoorv Sinha, CEO of Carbon Upcycling Technologies. \"Investigating industrial residue that could be upcycled will unlock the applicability of our technology to achieve emissions reduction in concrete products globally. This works towards a larger vision of beneficiating under-utilized materials, such as natural pozzolanic materials, to reduce the use of portland cement in commercial concrete mixes. We've already shown the ability to reduce cement use by over 10% in field deployments across Calgary and are confident that this number can be significantly improved with further research and development.\"\nRead the original article on CEMEX.", "pred_label": "__label__POS", "pred_score_pos": 0.7442384958267212}
{"content": "There has been much controversy in the media lately about the status of families who are separated by U.S. citizenship or permanent residency. However, in Miami and elsewhere in the United States, family relationships are cherished, and the government has set up some programs to prevent children from being separated from their parents who have permanent residency, as long as they meet eligibility requirements.\nAccording to the U.S. Citizenship and Immigration Services, there are many programs that allow for family immigration opportunities not offered to other categories of immigrants. This is particularly true for sons and daughters who are considered children. They meet this requirement if they are under the age of 21 and unmarried, as children in these circumstances often depend on their parents for emotional, physical and financial support.\nThe USCIS provides some detailed guidelines about which children may be eligible for this immigration opportunity. When the child is born to married parents, or the genetic mother is filing the petition, the qualification is straightforward. If a green card holder married the child’s parent before the child turned 18, that step-child may qualify. An adoptive parent must meet several requirements. These include maintaining both physical and legal custody of the child for at least two years before the age of 16. Exceptions may apply in some situations, though.\nAnother situation that is less clear-cut involves a child of a father who was not married to the mother at the time of the birth. In this case, the father must legitimate the parent-child relationship, and the process is governed by the laws of the location of the father’s residence or the child’s. There are also exceptions that may be considered by the court if the father can demonstrate that there is a parent-child relationship, even if there is no legal legitimation.\nBecause of the many factors that may affect an application, a permanent resident may not want to rule out the possibility of a child’s immigration until all angles of the situation have been evaluated carefully.", "pred_label": "__label__POS", "pred_score_pos": 0.5023375749588013}
{"content": "Population ageing raises common challenges for cities: to adapt their environments physically and socially, so that older people’s quality of life remains unaffected.\nA transition towards a circular economy does not happen by itself; it needs to be supported and encouraged by policy and planning.\nPolycentric territorial patterns encourage more balanced development between regions and more co-operative urban-rural relationships.\nThis is a supportive page of our", "pred_label": "__label__POS", "pred_score_pos": 0.6639904975891113}
{"content": "Oxidative stress\nRubrerythrins Rubrerythrins are a family of proteins which contain two domains: a N-terminal erythrin-like domain containing a four helix bundle with a diiron site, and a C-terminal rubredoxin-like domain containing a FeCys4 center. These proteins were first isolated from anaerobic and microaerobic organisms, e.g., Desulfovibrio vulgaris, Clostridium and Porphyromonas species .They have also been isolated from archaea, e.g., Sulfolobus tokodaii, and eukarya, e.g., Trichomonas vaginalis. The function of these proteins is, as yet, not fully established, and different activities have been reported for them, such as ferroxidase, superoxide dismutase, pyrophosphatase and NADH peroxidase activity, the latter being the most consensual. Rubrerythrins have also been found to complement catalase null strains, and rubrerythrin deletion mutants are known to be more sensitive to oxygen and hydrogen peroxide. I have been studying the desulforubrerythrin from Campylobacter jejuni, which is a rubrerythrin type of protein, with a desulforredoxin domain with a FeCys4 center on the N-terminal.\nSuperoxide reductase Superoxide reductases are proteins involved on the reduction of the superoxide anion (O 2 .-) generating H 2O 2. These enzymes are quite distinct from the superoxide dismutases (SOD) since these ones are responsible for the dismutation of superoxide anion, while the SORs are only able to perform the reductive step. These proteins have been classified according to their iron-content in two families: 1Fe-SORs, initially named neelaredoxin due to their blue color, and the 2Fe-SORs, known as desulfoferrodoxins, that contains an extra iron atom coordinated by four cysteine-sulfurs in a distorted tetrahedral geometry [Fe(Cys)4]. Structurally these two families are similar, with a common domain harbouring the catalytic center. This center, where the reduction of superoxide occurs, is conserved and is a pentacoordinated iron ion with four equatorial histidine-imidazoles and one axial cysteine-sulfur in a square pyramidal geometry. These proteins are quite widespread among the three domains of life. I am currently interested on the structural determination and characterization of different proteins belonging to this family.\nFlavodiiron proteins Flavodiiron proteins have been described as part of the response mechanism against both nitrosative and oxidative stresses. This type of proteins are also widespread in anaerobic and facultative microrganisms, from the three life domains. Structurally these proteins are minimally composed by two domains, a metallo β-lactamase like domain, at the N-terminal, that contains a diiron site where reduction of oxygen or nitric oxide occurs, followed by a flavodoxin-like domain that contains an FMN group. More complex arrangements have been described, involving mainly extra domains at the C-terminus (e.g., rubredoxin or flavin reductases-like domains). I am currently interested on the structural determination and characterization of different proteins belonging to this family.", "pred_label": "__label__POS", "pred_score_pos": 0.5759636163711548}
{"content": "A rotating screw pump lifts water along its axis, although the position of the screw itself is fixed inside its housing. Similarly, an adiabatic modulation of a periodic potential can move particles from one potential minimum to the next. However, this so-called Thouless pumping loses its quantization in the presence of losses or when the drive is not adiabatic. Zlata Fedorova and colleagues have now shown that the quantization can be recovered if the dissipation is also periodically modulated.\nWhen they incorporated this modulation in their theoretical modelling, counter-propagating modes in a lossy system could no longer hybridize, which restored the quantization — even if the modulation of the driving potential was non-adiabatic. Fedorova and colleagues realized their model using coupled sinusoidal plasmonic waveguides, for which the periodically varying losses were achieved by modulating the cross-section that controls the mode confinement. Despite the optical demonstration, this dissipative Floquet engineering can be applied to a wider class of periodically driven systems.", "pred_label": "__label__POS", "pred_score_pos": 0.9824846386909485}
{"content": "A revised draft\nPIC/S Guidance on Good Practices for Data Management and Integrity in Regulated GMP/GDP Environments has been prepared by the PIC/S Working Group on Data Integrity, co-led by the Australian Therapeutic Goods Administration and UK MHRA.\nProviding inspectorates guidance in interpreting GDP/GMP requirements on data management and data integrity, including reporting, is one goal of this document. The guidance will also serve as a tool to facilitate a harmonized approach to inspections and ensure their quality, particularly regarding data integrity expectations.\nPIC/S published a first draft of this guidance in August 2016. Following feedback received from PIC/S Participating Authorities during its six-month implementation trial period, the Working Group updated and expanded that draft.\nTo help develop a focused stakeholder consultation on this document, PDA seeks substantive comments on specific questions relating to the proportionality, clarity and implementation of the guidance requirements.\nThe consultation period will be open from Nov. 30, 2018, to Feb. 28, 2019. Comments can be sent to PDA’s Vice President of Scientific and Regulatory Affairs\nTina Morris using the template found on the PDA website.", "pred_label": "__label__POS", "pred_score_pos": 0.7832086086273193}
{"content": "Any company, regardless of the size, does not want to spend money on things they believe, can be done “in-house”. The reality is that office cleaning is often the first expense companies eliminate when cutting expenses.\nThere is no doubt that it will save money on the...\nHow often do you wash your bed sheets? Do you wash them regularly? A while back, AllYou.com asked readers how often they wash their sheets. Turned out, the majority of the readers stripped the bed every 10 to 14 days, while a good many of them went three and even four...\nWe are all surrounded by bacteria. Yes, there are bacteria everywhere, even in the most unimaginable places. Disease-causing bacteria are called pathogenic. These come in many forms and can cause illnesses from an ear infection to strep throat to cholera. They can get...", "pred_label": "__label__POS", "pred_score_pos": 0.8473284840583801}
{"content": "The Los Angeles County Development Authority (LACDA) has a staff of project managers, construction managers, inspectors, and labor compliance officers who have successfully managed and completed projects cumulatively valued at over $100 million, including new construction or rehabilitation of libraries, community centers, parks, and public housing; and residential and commercial refurbishments involving public funds.\nThe LACDA manages projects in a complex regulatory environment. These projects can involve a broad range of complexity and uncertainty that must be managed from early project feasibility to construction completion. In addition, these projects or programs may have unique concerns and corporate or political mandates that may require a multi-faceted approach to development.", "pred_label": "__label__POS", "pred_score_pos": 0.9353340268135071}
{"content": "1.. Formalize a mentoring relationship with someone you trust.\nEvery entrepreneur, especially an introvert, can benefit from the perspective of another businessperson, ideally one who has prior experience in the domain you are about to enter. Asking someone to be your mentor is not a sign of weakness, and most mentors love to help.\n2. Turn existing connections into productive relationships.\nWe all know some people through friends, family, and social connections. Do your homework to determine which of these might be able to help, and make a sincere effort to turn these connections into win-win business relationships. That means proactively finding common exchanges of value.\n3. Actively expand your business networking activities.\nThis doesn’t mean randomly attending every networking event you can find, but it does mean joining and actively participating in a couple of entrepreneurs group in your area, such as a local business incubator.\n4. Increase your visibility and expertise in your domain.\nThese days, by starting a blog or publishing on the internet, you don’t have to be a social butterfly to get supporters and be recognized as an influencer. By helping others, and participating in online debates and industry events, you will find productive relationships emerge naturally with peers.", "pred_label": "__label__POS", "pred_score_pos": 0.7639561891555786}
{"content": "Biodiesel Retail and Storage Requirements\nAll biodiesel and biodiesel blends sold in Michigan must meet state fuel quality requirements, including ASTM D6751 specification. A refiner, distributor, or retailer cannot transfer or dispense biodiesel or biodiesel blends unless the fuel is visibly free of undissolved water, sediments, and other suspended matter. Additionally, a biodiesel retailer may not sell biodiesel or biodiesel blends drawn from a storage tank that has more than two inches of water or water-alcohol at the bottom. Any retailer of biodiesel or biodiesel blends must obtain a license from the Michigan Department of Agriculture for each operating retail location. (Reference Michigan Compiled Laws 290.642 - 290.647)", "pred_label": "__label__POS", "pred_score_pos": 0.9991335868835449}
{"content": "May 11, 2015 – Reported by the Huffington Post – “Where are you?” I stared expectantly at my dark phone screen, impatiently waiting for it to come to life. I knew that today only one person could understand my profound disappointment. Our vision had just been shattered, and for a moment, I seriously doubted our ability to piece it back together. It was over. We had lost. But could it really have been for nothing? In those minutes before my friend’s message lit up my phone, I knew I had a decision to make: fight or flight. I had chosen wrong before; I refused to make the same mistake. A buzz directed my eyes back to the now glowing screen. “Library. Coming?” I took a deep breath and reached for my phone. “Be there soon.”\nWhen my friend, Sy Abdul, approached me to apply for the University of Pennsylvania’s inaugural President’s Engagement Prizes — a $100,000 grant awarded annually to Penn seniors to design and implement local, national, or global engagement projects during the first year after graduation — I hesitated. I doubted my ability to open up about something that I had gone to such lengths to conceal in the past. Luckily, the necessity of our project inspired me to be brave.\nThe initial concept for our project, AsylumConnect, was borne out of Sy’s personal experiences as an LGBTQ asylum seeker in the U.S. Our premise was simple: to support people seeking political asylum in the U.S. because of sexual orientation or gender expression. We would accomplish this by creating the first ever website and mobile app specifically designed for LGBTQ asylum seekers. These platforms would feature a centralized catalog of available LGBTQ-friendly services by location, themed educational webinars, and animated how-to videos.\nAs we combined our distinct experiences into a singular effort to advance AsylumConnect, the line separating us from our project faded. What I uncovered during my research — what I was hearing from existing organizations and LGBTQ asylum seekers — deeply affected me. It altered my worldview and rearranged my priorities.\nThe reality is sobering for anyone….story continues below…", "pred_label": "__label__POS", "pred_score_pos": 0.7771271467208862}
{"content": "A hangover refers to a set of symptoms that occur as a consequence of excessive alcohol use. Typical symptoms include fatigue, weakness, thirst, headache, muscle aches, nausea, stomach pain, vertigo, sensitivity to light and sound, anxiety, irritability, sweating, and increased blood pressure. A hangover can vary from person to person.", "pred_label": "__label__POS", "pred_score_pos": 0.9978175759315491}
{"content": "A team of engineers at Marshall Space Flight Center developing solutions to mitigate potential thrust oscillations of the Ares 1 rocket have received approval for two options during a December 17 meeting of the Constellation Program Control Board. The options include an passive upper-plane C-spring isolator for shock absorption and a LOX tank damper to detune the LOX propellant resonance from the rocket structural resonance.\nThrust oscillations occur on all solid rockets due to a coupling of the structural resonance of the launch vehicle with the pressure wave created during burning of the solid rocket propellent. The presence of thrust oscillations are of concern to astronauts during launch of Ares 1 because significant thrust oscillations could present a danger to crew safety and response capabilities during launch. Early simulations of Ares 1 showed the potential for unacceptable thrust oscillations. However, neither the Ares 1-X test nor the DM-1 test of the Ares-1 solid rocket motors exhibited problematic thrust oscillations.\nThe development and incorporation of the isolators provides a further measure of conservatism and safety within the Ares 1 design and is indicative of a development program addressing real issues that arise during engineering design and testing.", "pred_label": "__label__POS", "pred_score_pos": 0.6816684007644653}
{"content": "Design collective Envisions have created a paving design scheme for Eindhoven, in the Netherlands, which aims to illustrate how the city’s streetscape could better showcase itself as a central hub for innovation in contemporary design.\nEnvisions is a collective of 24 designers, each of whom place importance on material innovation, with a focus not just on material aesthetics, but also on functionality and practicality.\nEnvisions’ Stone in Progress project was devised by Iwan Pol, Tijis Gilde, Tomas Dirrix, Sanne Schuurman and Simone Post.\nThe project is a paving strategy which aims to make Eindhoven's stones appear more diverse, by manipulating their colour, texture and structure.\nThe city had previously imposed the rule that all paving should be red, yet there were no limitations regarding the design or pattern of the paving.\nUsing previously used tiles around the city, the team employed three strategies to transform the stones into their chosen design: washing, cutting and stamping.\nEnvisions initially washed the stones using water jets which revealed the gravel that is ususally hidden inside the stones, giving each piece a unique pattern and texture.\nThe team’s cut out method involved cutting into the stones, into which new stones can be placed, adding new decorations to the design.\nThe stamping technique involves imprinting stones, creating wave-like patterns upon the surface of the object.\nThe team have also collaborated with concrete manufacturer, Morssinkhof, who focused on how Envision’s designs could be applied at an industrial scale.\nThis enabled the team to uncover new ways of working, for example, the team learnt that colour last much longer when it is inherent to the material.\nThe team also recognised that placing colour within stones isn't durable as the pigment only last for approximately four years, thus colour is best generated via the typical shades of natural gravel-based materials.\nTo view more about the project, visit Envisions’ website.", "pred_label": "__label__POS", "pred_score_pos": 0.6489783525466919}
{"content": "Your workers’ compensation doctor diagnosis your work-related injury. He or she may also refer you to other doctors and rehabilitation specialists who can help you recover. To do these jobs effectively, though, your doctor needs some information from you. Because...\nMost jobs require you to perform specific tasks over and over again. Office workers often spend long hours using a computer, while factory employees may repeat the same motion throughout the day to operate a machine or assemble a component. Over time, these motions...", "pred_label": "__label__POS", "pred_score_pos": 0.998211145401001}
{"content": "Sardenne, F., Hollanda, S., Lawrence, S., Albert-Arrisol, R., Degroote, M., & Bodin, N. (2017). Trophic structures in tropical marine ecosystems: a comparative investigation using three different ecological tracers. Ecol. Indic., 81, 315–324.\nRésumé: We looked at how three ecological tracers may influence the characterization and interpretation of trophic structures in a tropical marine system, with a view to informing tracer(s) selection in future trophic ecology studies. We compared the trophic structures described by stable isotope compositions (carbon and nitrogen), the total mercury concentration (THg) and levels of essential fatty acids (EFA) at both the individual and species level. Analyses were undertaken on muscle tissue samples from fish and crustacean species caught in the waters surrounding the Seychelles. The carbon isotope composition (delta C-13) correlated to the proportion of arachidonic acid (ARA), whereas the nitrogen isotope composition (delta N-15) correlated to the proportion of docosahexaenoic acid (DHA) and THg. At the individual level, trophic position obtained with these three last tracers are similar. In ' contrast, the eicosapentaenoic acid (EPA) was not clearly correlated to any of the tracers. At the species level, the use of EFA (ARA and DHA), as compared to stable isotopes, resulted in slight structural modifications, mainly in the middle trophic levels. For example, the EFA overestimated the trophic positions of Thunnus alalunga and Etelis coruscans but underestimated the trophic positions of other snappers and groupers. While ARA mainly originates from coastal/benthic areas, DHA is conserved throughout the food web and may be used as a proxy indicator of trophic position. However, metabolic disparities can affect ecological tracers and in turn, distort the trophic structures derived from their results. This is especially true for species with close trophic ecologies. Despite these caveats, we think that analysing at the individual level the wealth of ARA, DHA and THg data that has already been obtained through earlier nutrition or food security studies would enhance our understanding of trophic structures.", "pred_label": "__label__POS", "pred_score_pos": 0.6549457311630249}
{"content": "The HSE have updated their guide to Musculoskeletal Disorders (INDG143).\nThis leaflet (previously published in 2012) provides practical guidance on reducing the risk of injury from hazardous manual handling. It helps employers comply with their duties under the Manual Handling Operations Regulations 1992. They have revised the leaflet to bring it into line with their legal guide to the regulations (L23) and current ways of working. It now includes more advice on simple filters to help you identify low-risk tasks which do not need further assessment. They have removed the safe lifting tips from the leaflet, but they will be available from HSE’s website.\nThe leaflet is available here.", "pred_label": "__label__POS", "pred_score_pos": 0.995234489440918}
{"content": "Imagine Philanthropy for Europe\nPrivate money for the public good plays a significant role as foundation budgets in Europe amount to €60 billion annually. The current challenges and the sense of urgency force foundations to reinvent themselves, ready to take a greater responsibility, and to enable greater European solidarity. However, philanthropy with a European purpose remains unchartered territory.\nThe process of European integration seems to have stopped at the doorstep of the European philanthropic sector. Genuine European philanthropy is hardly existing, a niche. So, something needs to be done.\nPhilanthropy with a Europen purpose is yet to be imagined and resourced. And we know that we cannot do that alone. The Corona shock could become Europe’s moment and the moment for philanthropy to commit to our common ground, Europe.\nWith this study the European Cultural Foundation and the Allianz Kulturstiftung for Europe would like to invite you to a discussion to imagine European philanthropy for a common future.\nThe study will be available soon, but we hope this preview already kickstarts your imagination on European philanthropy.", "pred_label": "__label__POS", "pred_score_pos": 0.6076951622962952}
{"content": "Like many organisations, our work has been affected by the COVID-19 outbreak - here’s how we’re adapting!\nAlthough we had to cancel activities throughout February 2020, we know how important continued learning is to our participants. In addition to fears of the current situation, many of them now face the additional barrier of limits to their day off, so we’ve been exploring ways of engaging with them, particularly to address mental health concerns.\nWith our new website, participants can now access educational resources through their personal Enrich Accounts. We are sharing educational content on Facebook (English and Bahasa Indonesia), such as our \"Ask the Experts\" interviews and ‘learning packages’ from our Lunch & Learn lecture series (including takeaways, video clips and quizzes). We conducted a survey with our participants and learned that while the English/Tagalog-speakers prefer online classes, the Bahasa Indonesia-speakers prefer learning face-to-face; so we are running our first workshops using online conferencing tools as well as outdoor workshops in parks (with precautions in place). We encourage our participants to check our website first for the most updated course schedules.\nAdditionally, we are collaborating with Mind HK to translate their guide ‘Managing our Mental Health & Staying Well During a Virus Outbreak’ into Bahasa Indonesia and Tagalog. We are also taking this opportunity to work on internal projects, such as a new CRM system and accounting software, to ensure we are operating efficiently.\nWe appreciate the support we’ve received during this time and continue to grow and adapt to meet the needs of our participants.", "pred_label": "__label__POS", "pred_score_pos": 0.5096399188041687}
{"content": "Severe neuronal loss characterizes Alzheimer's disease (AD). However, the mechanisms by which neurons die remain elusive. Additionally, it is also unclear why some neurons within the same brain region are more resistant to neurodegeneration than others. In this application, we will attempt to address these two critical issues. We focus on necroptosis, a programmed form of necrosis, triggered by receptor-interactive protein kinases (RIPK) 1 and 3 and executed by the mixed lineage kinase domain-like (MLKL) protein. Upon activation by multiple inflammatory stressors, RIPK1 can trigger cell survival or cell death pathways, with the former being a default response to inflammatory stimuli. This default survival pathway is regulated, among others, by the Lys63- deubiquitylating enzyme cylindromatosis (CYLD) and MAPKAP kinase-2 (MK2), which ubiquitinate and phosphorylate RIPK1, respectively. We provide compelling evidence showing that necroptosis is activated in postmortem human AD brains and it correlates with Braak stage, brain weight, and tau pathology. We further show that blocking necroptosis in a mouse model of AD reduces neuronal loss. These novel and exciting data, together with the experiments proposed here, may answer two key but unresolved questions: 1. Which mechanisms do govern cell loss in AD? 2. What does make some neurons more susceptible to neurodegeneration than others? Our overarching hypothesis is that necroptosis contributes to neurodegeneration and selective neuronal vulnerability in AD.\nSpecific Aim 1 will identify the mechanisms linking RIPK1 activation to necroptosis induction in AD. Specific Aim 2 will identify the mechanistic link between RIPK1 and tau. Specific Aim 3 will determine the role of RIPK1 in the gene expression dysregulation observed in AD. Impact: Neuronal loss is a cardinal feature of AD and invariably affects multiple brain regions. Despite this indisputable evidence, the mechanism by which neurons die is still unknown. We propose that necroptosis is a key mechanism by which neurons die in AD and propose experiments to dissect the role of this pathway in AD fully. Our results will open new opportunities for research and interventions for this insidious disorder. From a basic biology perspective, these studies will uncover new and critical knowledge into the pathogenesis of this disease. From a therapeutic perspective, these studies will determine to what extent targeting necroptosis might be a valid approach to mitigate neuronal loss in AD.\nAlzheimer's disease is the most common form of dementia among the elderly and the sixth leading cause of death in the United States. This application aims at identifying the molecular bases underlying neuronal loss in AD. Elucidating these mechanisms will likely highlight several novel and clinically translatable targets; thus, aiding in the development of new treatment for AD.", "pred_label": "__label__POS", "pred_score_pos": 0.9167377948760986}
{"content": "Nielsen, a global measurement and data analytics company, recently released a Top Innovations report which has highlighted Kellogg’s Granola range as one of the Top 14 successful Innovations in South Africa. The brand won in the Nielsen’s ‘Brand Grower’ category. This award not only recognises cereal brands, but brands across all categories. This survey examined a wide range of products which were drawn from the food, personal care, beverages, and snacks categories.\nThe Kellogg’s name has been synonymous with iconic cereal brands such as Corn Flakes and All-Bran for generations, but, as consumers’ needs and tastes have broadened; the company has kept pace introducing new brands and products to meet these needs. “As a leading food company, this recognition and acknowledgement of our innovation success by this study, has affirmed that, as Kellogg’s, we are on the right track in our journey to delight our consumers through our product range.” Say Avik Sarkar, Marketing Director at Kellogg’s South Africa.\nThe report points out that at least 38% of local consumers enjoy trying out new products, and 41% actively search for new products. This confirms that there are opportunities for unique, tasty, and healthy foods for brands to remain relevant in a highly competitive market.In 2019, the Kellogg’s Granola range was repositioned with the ‘Indulge All Your Senses’ campaign that aimed to highlight how the range offers consumers wholesome, real ingredients that they can indulge on. “This year – 2020, we have amplified our campaign through a significant marketing investment across digital platforms and have partnered with influencers to drive the message and showcase our products to consumers at large.” Concludes Sarkar.", "pred_label": "__label__POS", "pred_score_pos": 0.9610174298286438}
{"content": "The Aga Khan University has launched a new mobile application, ‘CoronaCheck’, enabling people to safely evaluate coronavirus symptoms with an in-home screening tool of the application.\nAccording to an official statement, the app uses an interactive chatbot, driven by artificial intelligence, which allows users to understand their symptoms and recognise whether they may have contracted COVID-19 or not. With the app providing help promptly, it also aims to identify potential coronavirus carriers and limit their risk of transmission.\nThe application also provides guidelines for people to look after themselves if they are having any sort of symptoms of the highly contagious disease.\nBy reducing the need for suspected patients to visit hospitals for screening, the app will also contribute to curb the burden on the healthcare system and ensure care for those most in need.", "pred_label": "__label__POS", "pred_score_pos": 0.8852037191390991}
{"content": "Background: Increased fasting plasma glucose (FPG) and 2-hour postchallenge plasma glucose (PCPG) levels with normal hemoglobin A1c (HbA1c) levels are recognized as risk factors for cardiovascular disease. We undertook this study to determine the relationships between FPG and 2-hour PCPG levels over the normal HbA1c range and to assess the need to control FPG and 2-hour PCPG levels to achieve HbA1c targets recommended by the American Diabetes Association (ADA), International Diabetes Federation (IDF), and American College of Endocrinology (ACE). Methods: The data of all healthy individuals with HbA1c values less than 7.0% (N = 457) who underwent oral glucose tolerance tests between 1986 and 2002 for either screening as potential research volunteers (93%) or diagnostic purposes (7%) were analyzed. Results: Of 404 individuals with normal HbA1c levels (<6.0%), 60% had normal glucose tolerance, 33% had impaired glucose tolerance, 1% had isolated impaired FPG, and 6% had type 2 diabetes mellitus. Of 161 individuals without normal glucose tolerance, 80% had normal FPG levels. Both FPG and 2-hour PCPG levels increased as HbA1c increased and were significantly correlated (r = 0.63, P<.001), but the 2-hour PCPG level increased at a rate 4 times greater than FPG and accounted for a greater proportion of HbA1c. People who met the IDF and ACE HbA1c targets (<6.5%) had significantly lower 2-hour PCPG levels than those who met the ADA target (<7.0%) (P =.03), whereas FPG levels were similar. Conclusions: Most individuals with HbA1c values between 6.0% and 7.0% have normal FPG levels but abnormal 2-hour PCPG levels, suggesting that an upper limit of normal for FPG at 110 mg/dL (6.11 mmol/L) is too high and that attempts to lower HbA1c in these individuals will require treatment preferentially directed at lowering postprandial glucose levels.", "pred_label": "__label__POS", "pred_score_pos": 0.5945149660110474}
{"content": "Abstract\nPhysical activity is known to decline during pregnancy and the postnatal period, yet physical activity is recommended during this time due to the significant health benefits for mothers and their offspring. As a result of the COVID-19 pandemic and the restrictions imposed to reduce infection rates, pregnant and postnatal women have experienced disruption not just to their daily lives but also to their pregnancy healthcare experience and their motherhood journey with their new infant. This has included substantial changes in how, when and why they have engaged with physical activity. While some of these changes undoubtedly increased the challenge of being sufficiently active as a pregnant or postnatal woman, they have also revealed new opportunities to reach and support women and their families. This commentary details these challenges and opportunities, and highlights how researchers and practitioners can, and arguably must, harness these short-term changes for long-term benefit. This includes a call for a fresh focus on how we can engage and support those individuals and groups who are both hardest hit by COVID-19 and have previously been under-represented and under-served by antenatal and postnatal physical activity research and interventions.\nOriginal language English Article number 7304 Number of pages 9 Journal International Journal of Environmental Research and Public Health Volume 17 Issue number 19 DOIs Publication status Published - 7 Oct 2020 Bibliographical note© 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access\narticle distributed under the terms and conditions of the Creative Commons Attribution\n(CC BY) license (http://creativecommons.org/licenses/by/4.0/).\nKeywords Behaviour change COVID-19 Physical activity Postnatal Pregnancy Theory", "pred_label": "__label__POS", "pred_score_pos": 0.9938326478004456}
{"content": "Human immunodeficiency virus/Hepatitis B virus (HIV/HBV) co-infections are frequently observed due to shared routes of transmission, with reported figures indicating 6-9% of HIV-infected individuals in developed countries are chronically infected with HBV. HIV infection impacts on the natural progression of HBV infection, increasing levels of HBV replication and the risk of liver-associated mortality. Liver diseases associated with HBV are affected by the antiviral drugs used for HIV infection (toxic side effects), the current immune function in the patient, by improvements in the immune system brought about by control of the HIV infection, and by the development of resistance to the antiviral agents used for both the hepatitis B and the HIV infection. Tenofovir (TDF) is a newer antiviral drug that is frequently used for HIV infection and is also highly active against hepatitis B; however it is still unknown whether resistance to TDF will eventually develop and how this will affect the long-term outcomes\nCohort\nThere is one SNP\nWe did not identify the\nmutation rtA194T or rtV214A/\nQ215S in individuals failing TDF and found that the only\npersisting mutations were LMV-resistant mutations. --- Q215S ---", "pred_label": "__label__POS", "pred_score_pos": 0.8982529640197754}
{"content": "Gastric Dilatation Volvulus (GDV)\nGastric Dilatation Volvulus (GDV) is a multifactorial issue that can be caused by a combination of genetics, anatomy, and environmental factors. GDV is the twisting of the stomach in a way that cuts off blood supply, trapping gasses and creating a life-threatening circumstance. Typically, larger dog breeds or breeds with narrow, deep chests are at a higher risk for GDV, and that risk increases with age. Cats and small dogs can still develop GDV, though it is very rare.\nGDV is a two part process in which the stomach first bloats or dilates, filling with air, then undergoes torsion or volvulus, spinning on its axis. In less severe cases, a pet suffers from bloat (gastric dilatation) alone. The actual twisting of the stomach (volvulus) is a life-threatening situation that can be fatal within a matter of minutes. When a pet suffers GDV it can then cause the following emergencies:\nSwollen stomach.\nPressure on the abdomen.\nDamage to cardiovascular system.\nDecreased blood flow.\nIf your pet can burp or vomit it is probably not experiencing GDV. However, if your pet seems to be in excruciating pain, contact our office immediately and we can initiate tests to check for torsion.\nAbdominal pain.\nAnxiousness.\nDepression.\nDifficulty breathing.\nExcessive salivation.\nHardness developed in the stomach.\nSudden collapse.\nUnexplainable weakness.\nVomiting or dry heaving.\nGastric dilatation is considered an emergency situation. Once your pet arrives, we will assess their condition and administer any necessary pain relievers or antibiotics prior to gastric decompression. After relieving the bloat from the stomach, we will perform X-rays to determine if your pet is suffering from dilatation alone or if volvulus has also occurred.\nIf volvulus is present, surgical options will be discussed. Surgery is necessary to return internal organs to their normal positioning, and permanent gastropexy (surgically securing stomach in upright position) is often recommended. Once a volvulus has occurred, 75 to 80% of dogs develop it again; gastropexy can prevent future reoccurrences of GDV. If you witness any of these changes in your pet, please contact our office immediately as it could indicate a serious health emergency.", "pred_label": "__label__POS", "pred_score_pos": 0.7470105290412903}
{"content": "In desperation, you need desperate measures. The Corona Virus Pandemic has exposed severe obstacles across daily life. It has compelled social isolation that has paved the way for an immense crisis in personal and professional spheres.\nSoftware is the only effective way to keep people connected these days. It pushes software companies to take up more significant effort to win new clients and retain their existing clientele. It paves the way for immense competition in the IT domain.\nWith ever-rising race, software companies now have lesser margins for errors. They are putting their best to ensure the qualitative aspect of their products. A software bug is strong enough to trigger irreversible damages to a brand and the revenue figure. As such,\nQA Outsourcing services are all set to get paramount importance in the domain of technology.\nIT professionals are finding an adamant time in combating these challenges. Their focus is to ensure the company’s existence, leave apart the chances of consolidating the revenues. However, this crisis time is a high potential for companies to prepare themselves for the forthcoming times. Here are the tricks and tips that software companies should inevitably follow to find a way-out through challenging times.\nFocus on delivering complete testing services with ¼th workforce\nBusinesses of all types and sizes are cutting down their operational spending plans. They are getting compelled to drain their talents to keep the operational expenses within control. However, it never calls for limiting the extent of Testing. Instead, your focus should be on maximizing the area in this regard. The only way to materialize this plan is to optimize the hourly production rate. Even if businesses have the responsibility to minimize the count of jobs-lost, it cannot retain its operation, if the fixed cost gets to an alarming extent. Hence, optimizing the workforce becomes crucial.\nTesting must cover Performance and Functionality Testing Software Testing involve Test Automation as a critical component. The Automation process is to automate the practice of testing an application. The scope of work in this regard comprises two significant aspects- Performance and Functionality Testing.\nFunctional Testing involves the orientation to validate AUT Errors, maturing out of its functionality. For example, once a user hits the Login Tab. He/she should move to the Navigation page.\nPerformance Testing is all about verifying the total performance and the system’s scalability under Load. It gets measured by evaluating the time taken across the complete transaction for the data that flows between the terminals. Besides, it involves the evaluation of the sustainability of users. Usually, log-in communication is likely to take a second for one thousand users.\nWorking with testers without experience in Test Automation\nUsually, Software Testing services involve manual Testing. In the majority instances, the Quality Assurance team gets dominated by professionals without experience in coding or Test Automation. These instances come as the most severe challenges for testing team leaders.\nThe real-time professional domain will hardly allow the luxury to learn new things or play the Trial and error game. Hence, companies are looking for personnel who are conversant with Test Automation and Coding. Therefore, Testers with profound experience in Test Automation will get preference over their counterparts, who are yet to have hands-on experience on Test Automation.\nCompanies have some unsolicited experience, trying Test Automation in the past.\nThe majority of businesses tried implementing Test Automation and ended up making some unwanted experience. The significant part of their effort and their budget likely got exhausted in maintaining scripts than regressing Testing. If you aspire to taste significant success in this regard, you must approach the implementation process in a considerate manner. You must ensure that you are picking appropriate tools that support the application undergoing the test. Most importantly, the device needs to be compatible with the specific Development Life cycle.\nIn the majority instances, Test Automation teams focus on optimizing the return on investment, or they are reluctant about investing in similar tools unless they get substantial results. Hence, these teams prefer working with Free Tools that never suits the professional working ambiance. It is hard to ensure efficient Testing if your team is working with such low-end tools.\nCompanies are trying Test Automation without substantial results.\nMany businesses are working with Test Automation over the last few years. However, deploying only a handful of engineers cannot cope with the ideal schedule for Regression Testing. In case your organization has made a similar experience, it demands you to reconsider your Test Automation Framework.\nSuppose you are targeting the optimum return on your investment in Testing Automation. In that case, you inevitably need to downsize the Articrafts to the extent possible. Portability On Cross-Platform and the Shareability of the Testing Automation Framework Components hold paramount significance in this regard. For example, a line of Test Automation Coding is equivalent to the expenses in per-minute Script Maintenance. It gets determined by the tools you deploy across the Test Automation process.\nAUT Demands Testing across various platforms with broader scripts\n· AUT, majorly demands testing across multiple web browsers and operating systems.\n· The majority of companies hold the notion that it is impossible to retain their present testing frequency with the workforce downsized to 1/4th of the actual workforce volume.\nEnsure considerate selection of the Testing Tools\nExperts suggest that these companies should pick Test Automation Tools that feature a single test execution with a single script. It enables a company to operate with a unique text, rather than having multiple scenarios to facilitate Test Automation.\nCompanies can even redesign their Test Automation Framework. Ideally, they should give their framework an event-oriented, logic-rich, Data-intensive, and modular design. Such a configuration facilitates streamlining all business logic upon a sole Test process that will deal with Procedural Test, involving test data.\nConsidering the points discussed above, companies put their sincere efforts to automating their testing methodology to optimize team productivity. Most importantly, they must make a wise selection of the tools that match the team’s ability and skill sets and become compatible with their development plans. There are no other alternatives than to design Test Automation Architecture in a precise manner for downsizing the persistent maintenance needs.", "pred_label": "__label__POS", "pred_score_pos": 0.5580767393112183}
{"content": "City Controller Alan Butkotvitz recently commissioned a citywide survey, which found that Philadelphia’s “eds and meds” spend over $5 billion annually on good and services. This finding has prompted Butkotvitz to explore opportunities for how local anchor institutions can boost local employment by shifting 25 percent of their procurement to local vendors. The Democracy Collaborative was pleased to be asked to contribute to the report.", "pred_label": "__label__POS", "pred_score_pos": 0.9383477568626404}
{"content": "What foods are in the Protein Foods Group?\nAll foods made from meat, poultry, seafood, beans and peas, eggs, processed soy products, nuts, and seeds are considered part of the Protein Foods Group. Beans and peas are also part of the Vegetable Group.\nBeans and peas are the mature forms of legumes. They include kidney beans, pinto beans, black beans, lima beans, black-eyed peas, garbanzo beans (chickpeas), split peas and lentils. They are available in dry, canned, and frozen forms. These foods are excellent sources of plant protein, and also provide other nutrients such as iron and zinc. They are similar to meats, poultry, and fish in their contribution to these nutrients. Therefore, they are considered part of the Protein Foods Group. Many people consider beans and peas as vegetarian alternatives for meat. However, they are also considered part of the Vegetable Group because they are excellent sources of dietary fiber and nutrients such as folate and potassium. These nutrients, which are often low in the diet of many Americans, are also found in other vegetables.\nBecause of their high nutrient content, consuming beans and peas is recommended for everyone, including people who also eat meat, poultry, and fish regularly.\nThe Food Patterns also indicate that beans and peas may be counted as part of the Protein Foods Group. Individuals can count beans and peas as either a vegetable or a protein food.\nGreen peas, green lima beans, and green (string) beans are not considered to be part of the beans and peas subgroup. Green peas and green lima beans are similar to other starchy vegetables and are grouped with them. Green beans are grouped with other vegetables such as onions, lettuce, celery, and cabbage because their nutrient content is similar to those foods.\nSelect a variety of protein foods to improve nutrient intake and health benefits, including at least 8 ounces of cooked seafood per week. Young children need less, depending on their age and calorie needs. The advice to consume seafood does not apply to vegetarians. Vegetarian options in the Protein Foods Group include beans and peas, processed soy products, and nuts and seeds. Meat and poultry choices should be lean or low-fat.", "pred_label": "__label__POS", "pred_score_pos": 0.5064996480941772}
{"content": "Selina Hofstetter - Making Suffrage Work: The impact of female suffrage in different environments\nI exploit quasi-random local franchise extensions to Swiss women in the late 20th century to empirically identify the political impact of female suffrage in different contexts. First, I analyze municipalities with a male majority in favor of women’s vote and ones with a majority against it. I further study municipalities with a parliament versus direct-democratic assemblies. My findings show that female suffrage caused a right-wing effect in municipal party vote shares and expenditure. However, municipalities that favored female suffrage moved more center-right than right, and experienced a lower drop in electoral turnout. Municipalities with a parliament instead of an assembly making budget decisions, experienced an increase instead of a drop in expenditure. I complement my findings with a national election survey from 1972 to show that the effects might be driven by differences in women’s political interest.\nI am a Postdoctoral Fellow at Stanford University’s Democracy & Polarization Lab. I hold a Ph.D. in Political Science from the London School of Economics (LSE). My research analyses the performance of democratic institutions with a focus on women.\nI use empirical quantitative methods with a focus on causal inference, but I am also familiar with game theory and very interested in co-authoring with formal theorists. For my dissertation on the introduction of local female suffrage in Switzerland, I collected and coded an unique historical dataset at the Swiss municipality level between 1940-1990. To complete this, I received support from the Baroness Birk Award and the STICERD Ph.D. Grant.\nFrom March until June 2020, I visited Uppsala University. From September 2019 until March 2020, I was a visiting researcher at the University of Pennsylvania. I attended the EITM Summer Institute at Emory University in 2019 and the Zurich Summer School for Women in Political Methodology in 2017.", "pred_label": "__label__POS", "pred_score_pos": 0.5195288062095642}
{"content": "Sitra’s working paper proposes 35 steps for implementing the European data strategy, highlighting the need to include personal data on the agenda.\nThe European Commission’s new data strategy aims to create a common European data space, that is, a single market for data, which will allow data to flow freely within the EU and across sectors for the benefit of businesses, researchers and public administrations.\nSitra’s working paper, created together with the A New Governance initiative, proposes 35 future-proof steps for policymakers and companies to take in the short and long term to make the vision outlined in the European data strategy work. The proposals, targeted at the European Commission, the EU’s member states, industry, those creating data sharing initiatives and the research field, are grouped into four main topics according to the strategy chapter in the data strategy:\nthe management of the cross-sectoral availability and reuse of non-personal and personal data; the creation of an infrastructure for data markets; the empowerment of individuals and businesses through the reuse of data; the development of a complementary cross-sectoral personal data space.\n“It is hard to make a clear-cut distinction between industrial (non-personal) and personal data. A good example is data collected by vehicles. Without including personal data in the data strategy, a significant amount of data is excluded from the data markets, and consequently cannot be exploited for innovation purposes,” notes\nLaura Halenius, Senior Lead on Sitra’s IHAN project. A European single market for data enables innovation\nCurrently, there is not enough data available to promote innovation. To make data fully available to public entities and companies of all sizes, we propose actions such as developing common standards and best practices, providing investment, and building cloud services to ensure the creation of the necessary infrastructure for functioning data markets.\nTo promote cross-sectoral data sharing, we propose the creation of a governance body that would help to ensure the interoperability of different data spaces, a human-centric approach at all stages of decision-making, and close co-operation with the European standardisation bodies.\nFor businesses, non-personal and personal data sharing is key to creating new business models and innovative services. To overcome the lack of trust and skills that prevent individuals from sharing data, people need to be motivated by innovative services that add real value to their lives. We also propose the creation of a “fair data label” for trustworthy digital services.\n“Better use and sharing of data is also crucial in the current Covid-19 crisis and its aftermath – it will enable governments and businesses to respond to future challenges more efficiently,” notes\nMarkus Kalliola, Senior Lead on the IHAN Project at Sitra. “European companies need support and funding to renew their business models to respond to the changed operating environment.”\nTo unleash the full potential of Europe in the digital age, we recommend the co-ordinated development of data spaces. We also recommend adding a horizontal and cross-cutting personal data space to the data strategy alongside the sector-specific data spaces.\nMore information Read more in Sitra’s working paper, 35 proposals to make the European data strategy work, compiled by Sitra’s fair data economy project in collaboration with the A New Governance initiative. Sitra’s working papers provide multidisciplinary information about developments affecting societal change. They are part of Sitra’s future-oriented work conducted by means of forecasting, research, projects, experiments and education.", "pred_label": "__label__POS", "pred_score_pos": 0.6283981800079346}
{"content": "In 2019, the bubble well-and-truly burst for pot stocks, sending many investors running for the hills. Now, it looks like we're seeing the cannabis industry rally back up.\nAs we've covered extensively, 2019 was not a kind year for cannabis investors, and by the time the COVID-19 pandemic became widespread in March 2020, the American Cannabis Index was valued at just a tenth of its value in the previous year.\nWhile COVID-19 was itself largely responsible for what is now being called the \"March 2020 crash,\" the cannabis industry was already dealing with internal issues that had sullied investor confidence.\nOverpriced valuations, a persistent black market, cash hemorrhaging, and a lack of available funding all converged to bring the cannabis industry to its knees.\nIn response to these issues and the COVID-19 crisis, many companies began to cut costs wherever possible. Canopy Growth laid off over 1,000 staff, and ceased operations across three continents, OrganiGram cut 45% of its workforce and Aurora cut hundreds of jobs, including 25% of its corporate positions in February.\nBut now, as we enter the final quarter of 2020, it's beginning to look like pot stocks are beginning to bounce back.\nAs shown above, the American Cannabis Index on New Cannabis Ventures has increased by over 260% since mid-March. Additionally, the ETF ETFMG Alternative Harvest (MJ) has climbed 50% since that same period. While these current gains felt by the industry admittedly pale compared to its 2018 bubble-heights, we may be seeing a more realistic evaluation of the cannabis industry's trajectory and potential.\nAnd it looks as though portfolio managers are beginning to think the same, with Investopedia reporting that the Boston-based investment manager 'Putnam Investments LLC' had purchased 6 million shares of the U.S.-based cannabis MSO 4Front Ventures, and Wasatch Advisors Inc., a Utah-based asset manager, is now the second-largest holder of Cresco Labs shares.\nEvidently, investor sentiment is slowly but surely returning to the cannabis industry, and there are several reasons for this. As we've discussed previously, the COVID-19 pandemic brought some unexpected benefits to the cannabis industry.\nDuring the pandemic, cannabis stores were deemed \"essential,\" and throughout the world recreational and medicinal cannabis sales climbed despite the ongoing economic downturn. Additionally, it is likely that the cost-cutting measures implemented by cannabis companies in the face of the COVID-19 pandemic sat well with investors, who have been watching capital pour out of the industry at sky-high rates.\nHowever, as is often the case, some companies have thrived more than others during this growth period for the cannabis industry. Let's take a look at two of the top performers during the second half of 2020.\nDisclaimer: Past performance is not an indicator of future performance.\nFew marijuana stocks have performed as well as Green Thumb Industries has recently, as the company's recent quarterly results show. Had investors bought into GTI stock during the March 2020 crash, they'd be up roughly 300% right now.\nEmploying an 'enter, open and scale' strategy, Green Thumb Industries (CSE: GTII) is a Multi-State Operator that owns and operates a series of cannabis stores throughout the United States called Rise™ and Essence. GTI has 13 manufacturing facilities, 48 stores open across the U.S, and enough licenses for a total of 96 retail locations and operations across the country.\nGreen Thumb's family of consumer brands is produced, distributed, and available in retail locations in nine states: California, Colorado, Connecticut, Florida, Illinois, Maryland, Massachusetts, Nevada, and Pennsylvania, and Green Thumb currently employs over 1,800 people.\nAs per the recent quarterly results, GTI managed to bring in over $100 million for the second consecutive quarter, with the most recent quarter bringing in $119.6 million for the company. This represents a 167.5% increase year-over-year and a 16.6% increase over the previous quarter. In the first half of 2020, GTI has already exceeded the company's total revenue for 2019.\nWhile Green Thumb Industries reported a net loss of $12.9 million this quarter, the company's adjusted EBITDA was $35.4 million, which was leaps and bounds higher than the adjusted EBITDA of $2.3 million during the same period last year.\nDisclaimer: Past performance is not an indicator of future performance.\nGreen Thumb Industries wasn't the only cannabis company to have a stellar second quarter, with GrowGen also achieving solid growth over the period, as revealed by its own Q2 results for 2020.\nGrowGeneration Corp. is the largest hydroponic supplier in the US since its founding in 2014. GrowGen currently has 28 organic garden centers across 10 states, allowing the company to supply the cannabis industry with crucial lighting technology, pest controls, ventilation, soils, and propagation supplies.\nDuring the most recent quarter, GRWG enjoyed a 123% revenue increase, from $19.5 million during Q2 last year, to $43.5 million for Q2 2020. Additionally, GrowGen's Adjusted EBITDA was $4.6 million for Q2 2020 compared with $1.7 million for Q2 2019, an increase of 166% or $0.12 per share.\nHad investors bought GrowGeneration stocks during the March lull, they similarly would have enjoyed returns of over 300%.\nMoreover, not only is GrowGeneration's balance sheet moving quickly in the right direction, but the company is an ancillary stock, one that we've identified previously as a key \"pick and shovel\" company. The ancillary nature of the company buttresses it against the unpredictability of the cannabis industry more generally, specifically when compared with \"plant-touching\" companies.\nGrowGeneration projects that sales could reach $260 million, with an Adjusted EBITDA of roughly $28 million throughout 2021.\nGet the Latest Marijuana News & Content in your Inbox!\nAll your support helps The Green Fund keep writing content for all you\nmarijuana enthusiasts and potential pot stock investors", "pred_label": "__label__POS", "pred_score_pos": 0.7672790288925171}
{"content": "FTSE 100 listed chemicals and tech company, Johnson Matthey (LON:JMAT), watched its share price shed 5% on Thursday, as the company saw its bottom line contract significantly during the recent half-year of trading.\nThe company reported that sales fell by 20%, driven by reduced demand for its Clean Air, Efficient Natural Resources and New Markets offerings. Despite this, reported revenues rose by 2%, led by increases in average previous metals prices.\nFollowing the trend of painful fundamentals, its reported operating profits contracted by 74%, from £259 million to £68 million. Similarly, profit before tax dropped by more than 88% year-on-year, following ‘major’ impairment and restructuring charges of £78 million.\nIn terms of its balance sheet, Johnson Matthey reported cash flow of £482 million, while its net debt to EBITDA ratio stood at 1.6 and its return on invested capital fell to 10.6%, pushed by lower operating profit.\nThe situation was equally rough for the company’s shareholders, with reported EPS falling 87%, to 12.3p, and the interim dividend per share sliding 18% to 20.0p, due to reduced profits and higher net finance charges.\nResponding to the challenges pandemic trading environment, and looking to the future, Chief Executive, Robert MacLeod said: “ It has been a challenging period but the steps we have taken in recent years to create a more simple, agile and efficient business, coupled with the dedication of all my colleagues across the whole of Johnson Matthey, have enabled us to navigate it well. I am pleased that we delivered operating performance ahead of market expectations, as well as good cash generation, and made further progress on transforming the group.”\n“[…] I am excited by our medium term growth prospects driven by accelerating global trends and we are purpose led to reduce the impact of climate change. We are investing for our future and remain focused on executing our growth opportunities including battery materials, fuel cells and our hydrogen production technologies.”\nFollowing the stinging trading update, Johnson Matthey shares fell by 4.59%, to 2,433.00p a share 19/11/20. This price is below its post-lockdown high of 2,654.00p a share, but fairly consistent with its going rate over the last six months.\nAnalysts currently have a consensus ‘Hold’ stance on the stock and a target price of 2,555p – which is roughly where it began the day. It’s p/e ratio of 18.40, which looks like good value versus the basic materials sector average of 26.81. The Marketbeat community currently has a 53.32% “underperform” stance on the stock.", "pred_label": "__label__POS", "pred_score_pos": 0.9597305059432983}
{"content": "O'Brien T, Social control and trust in the New Zealand Environmental Movement, Journal of Sociology, Volume 51, Issue 4, 2015, Pages 785-798\nAbstract:\nEscalating concern regarding environmental issues has resulted in an increase in the number and scope of environmental movements internationally. The diversity and proactive nature of these movements has put pressure on public (state) actors to address challenges and engage with movement actors. Engagement is not universally positive and can lead to attempts at disruption or subversion of challenging movements. This article examines the impact of perceived state subversion on trust within the New Zealand environmental movement through the alleged use of spies. The analysis finds that short-term emotional reactions within the movement that led to questioning of relationships were outweighed by longer-term pragmatic view about the need to maintain collective action", "pred_label": "__label__POS", "pred_score_pos": 0.9876022338867188}
{"content": "Abstract\nAmyloid precursor protein (AβPP), a precursor of amyloid β (Aβ) peptide, is one of the molecules involved in the pathogenesis of Alzheimer's disease (AD). Specific mutations in AβPP have been found in patients inheriting familial AD (FAD). These mutant AβPP proteins cause cell death in neuronal cell lines in vitro, but the molecular mechanism of cytotoxicity has not yet been clarified completely. We analyzed the cytotoxic mechanisms of the London-type AβPP mutant, V642I-AβPP, in primary cortical neurons utilizing an adenovirus-mediated gene transfer system. Expression of V642I-AβPP protein induced degeneration of the primary neurons. This cytotoxicity was blocked by pertussis toxin, a specific inhibitor for heterotrimeric G proteins, Go/i, and was suppressed by an inhibitor of caspase-3/7 and an antioxidant, glutathione ethyl ester. A specific inhibitor for NADPH oxidase, apocynin, but not a xanthine oxidase inhibitor or a nitric oxide inhibitor, blocked V642I-AβPP-induced cytotoxicity. Among mitogen-activated protein kinase (MAPK) family proteins, c-Jun N-terminal kinase (JNK) and p38MAPK, but not extracellular regulated kinase (ERK), were involved in this cytotoxic pathway. The V642I-AβPP-induced cytotoxicity was not suppressed by two secretase inhibitors, suggesting that Aβ does not play a major role in this cytotoxicity. Two neuroprotective factors, insulin-like growth factor I (IGF-I) and Humanin, protected these primary neurons from V642I-AβPP-induced cytotoxicity. Furthermore, interleukin-6 and -11 also attenuated this cytotoxicity. This study demonstrated that the signaling pathway activated by mutated AβPP in the primary neurons is the same as that by the other artificial insults such as antibody binding to AβPP and the artificial dimerization of cytoplasmic domain of AβPP. The potential of neurotrophic factors and cytokines in AD therapy is also indicated.\nKeywords Alzheimer's disease Humanin NADPH oxidase Neurodegeneration c-Jun N-terminal kinase ASJC Scopus subject areas Cellular and Molecular Neuroscience", "pred_label": "__label__POS", "pred_score_pos": 0.6477137804031372}
{"content": "Abstract\nAll people are vulnerable to having their self-concepts shaped by others. This article investigates that vulnerability using a theory of narrative self-constitution. According to narrative self-constitution, people depend on others to develop and maintain skills of self-narration and they are vulnerable to having the content of their self-narratives co-authored by others. This theoretical framework highlights how vulnerability to co-authoring is essential to developing a self-narrative and, thus, the possibility of autonomy. However, this vulnerability equally entails that co-authors can undermine autonomy by contributing disvalued content to the agent’s self-narrative and undermining her authorial skills. I illustrate these processes with the first-hand reports of several women who survived sexual abuse as children. Their narratives of survival and healing reveal the challenges involved in (re)developing the skills required to manage vulnerability to co-authoring and how others can help in this process. Finally, I discuss some of the implications of co-authoring for the healthcare professional and the therapeutic relationship.\nKeywords Autonomy Co-authoring Narrative Vulnerability", "pred_label": "__label__POS", "pred_score_pos": 0.999946117401123}
{"content": "Abstract\nDespite considerable examination of gender and gender equity within early childhood education, gender inequity remains problematic in many early childhood settings. Using qualitative methods, the study reported in this article investigated four early childhood teachers’ understandings about gender and their commitment to promoting gender equity. It adopted a triangulated investigation of the teachers’ understandings, attitudes and commitment to gender equity that involved talking with the teachers about their practice, observing their pedagogic practice, and inviting them to reflect on gender-based scenarios. While the participants believed gender to be a significant issue for early childhood teachers, their understandings about many aspects of gender and gender equity were heavily grounded in socialisation theory. In addition, their reliance on socialisation theory seemed to contribute to a sense of fatalism regarding their capacity for intervention. The study concludes that engaging with feminist poststructuralist theory may enhance teachers’ understanding about gender and gender equity and offer a way of intervening effectively at the local level.\nOriginal language English Pages (from-to) 21-27 Number of pages 7 Journal Australian Journal of Early Childhood Volume 30 Issue number 1 Publication status Published - 2005 Keywords preschool education sex role teachers", "pred_label": "__label__POS", "pred_score_pos": 0.6465624570846558}
{"content": "In the decades following World War II, psychology as a science made notable strides in diagnosing and treating pathologies. While the contribution of psychological research on mental illness and adversity has …\nEMOTIONAL INTELLIGENCE\nEmotional wellbeing, self-empowerment, and emotional breakthrough support and coaching is Bethany’s skill and passion. Her mission is to inspire and empower you to reach your personal, physical, health and emotional wellbeing.\nCERTIFIED HYPNOTHERAPIST\nHypnotherapy has evolved by gaining insights from a range of current psychological and therapeutic disciplines. This means that as a Cognitive Hypnotherapist I have a wide range of tools and techniques to help you get over your problems.\nGrief and loss are only a part of the story of your loved ones passing. Being able to recount, discuss and engage with everything that happened before and during the time your loved one was passing to an intuitive guide who has come through the pain herself, is a profoundly healing experience in and of itself.\nSPIRITUAL INSIGHT\nExplore the limitless potential of your soul and let yourself soar with full practical advice on the aura, chakra energy centers and meditation and everything you need to know about aligning with your spiritual soul-self, activating your intuition and connecting with the ‘god’ force and spirit-world.", "pred_label": "__label__POS", "pred_score_pos": 0.9708217978477478}
{"content": "2020 has been a year of stark challenges, exposing privilege and inequity across economic, health and educational systems. Equity, specifically in the context of education, refers to every student having the resources and support they need in order to succeed academically. The opportunities for learning for students during the COVID-19 pandemic have been mired by inequity – varying drastically and have been correlated with student location, racial demographics, family income-level, and special needs.\nWhile digital inequities existed and impacted students before COVID-19, the shutdown of physical school buildings has exacerbated them and brought necessary attention to the issue. This Digital Divide is one manifestation of inequity in education and describes the gap between students who have sufficient access to and knowledge of technology to succeed academically, and those who do not. The resiliency of educational systems across the world has been tested during this pandemic, and those students most impacted by the Digital Divide have faced the biggest challenges in continuity of learning.\nWe know access is a foundational piece of educational equity and for many years, access to institutionalized education was inherently tied to the access to physical school buildings. No matter the background and individual challenges of students, once inside the walls of a school, students had the opportunity to learn. However, a student’s ability to learn has always been determined in part by their access to learning opportunities once they leave the school, including digital access.\nThere is an opportunity to increase educational equity – in the midst of these challenging times- by addressing the Digital Divide head on, affirmatively examining inequities, and investing in solutions that support access to and resilience of learning opportunities for all students.\nIn our recently released discussion paper “Education Equity, the Digital Divide, and COVID-19“ we examine some of the equity concerns correlated with COVID-19 and K–12 education— and provide foundational knowledge in the hopes of facilitating meaningful action towards alleviating inequity and creating resilient systems of learning. It includes recommendations for how education leaders can use this crisis as an opportunity to propel us into a future where all students have more robust and equitable learning opportunities.", "pred_label": "__label__POS", "pred_score_pos": 0.595733642578125}
{"content": "This study evaluates the effectiveness of contracting out mandatory publicly provided counselling and training for long-term unemployed in Flanders (Belgium) to private for-profit and non-profit organisations (FPOs and NPOs). A multivariate transition model exploits timing-of-events and novel exclusion restrictions to account for selection on unobservables. Overall, the intervention was highly effective in reducing unemployment duration, but also spurred employment instability and withdrawals from the labour force. FPOs slightly, but significantly enhanced exits to employment without reinforcing recidivism relative to the public provider but not significantly relative to NPOs. FPOs also charged lower prices and hence were the best performing providers.\nSubjects:\ncontracting out of employment services non-profit versis profit private provision of public services timing-of-events long-term unemployment", "pred_label": "__label__POS", "pred_score_pos": 0.8498795628547668}
{"content": "BACKGROUND. Transcriptome sequencing (RNA-seq) improves diagnostic rates in individuals with suspected Mendelian conditions to varying degrees, primarily by directing the prioritization of candidate DNA variants identified on exome or genome sequencing (ES/GS). Here we implemented an RNA-seq guided method to diagnose individuals across a wide range of ages and clinical phenotypes. METHODS. One hundred fifteen undiagnosed adult and pediatric patients with diverse phenotypes and 67 family members (182 total individuals) underwent RNA-seq from whole blood and fibroblasts at the Baylor College of Medicine (BCM) Undiagnosed Diseases Network (UDN) clinical site from 2014-2020. We implemented a workflow to detect outliers in gene expression and splicing for cases that remained undiagnosed despite standard genomic and transcriptomic analysis. RESULTS. The transcriptome-directed approach resulted in a diagnostic rate of 12% across the entire cohort, or 17% after excluding cases solved on ES/GS alone. Newly diagnosed conditions included Koolen-de Vries syndrome (KANSL1), Renpenning syndrome (PQBP1), TBCK-associated encephalopathy, NSD2- and CLTC-related intellectual disability, and others, all with negative conventional genomic testing, including ES and chromosomal microarray (CMA). Fibroblasts exhibited higher and more consistent expression of clinically relevant genes than whole blood. In solved cases with RNA-seq from both tissues, the causative defect was missed in blood in half the cases but none from fibroblasts. CONCLUSION. For our cohort of undiagnosed individuals with suspected Mendelian conditions, transcriptome-directed genomic analysis facilitated diagnoses, primarily through the identification of variants missed on ES and CMA.\nDavid R. Murdock, Hongzheng Dai, Lindsay C. Burrage, Jill A. Rosenfeld, Shamika Ketkar, Michaela F. Müller, Vicente A. Yépez, Julien Gagneur, Pengfei Liu, Shan Chen, Mahim Jain, Gladys Zapata, Carlos A. Bacino, Hsiao-Tuan Chao, Paolo Moretti, William J. Craigen, Neil A. Hanchard, Brendan Lee\nGuidelines: The Editorial Board will only consider letters that we deem relevant and of interest to our readers. We will not post data that have not been subjected to peer review, nor will we post letters that are essentially a reiteration of another letter. We reserve the right to edit any letter for length, content, and clarity. Authors will be notified by e-mail if their letters were accepted. No appeals will be considered. Specific requirements: All letters must be 400 words or fewer. You may enter the letter as plain text or HTML. The author's name and e-mail address are required, and will be posted with the letter. All possible conflicts of interest must be noted, even if they are not posted. If you wish to include a figure (keep in mind that non-peer-reviewed data will not be posted), please contact the editors directly at editors@the-jci.org.", "pred_label": "__label__POS", "pred_score_pos": 0.5350842475891113}
{"content": "The Sino-Vatican Agreement Renewal: Pro Deo or Pro Patria?\nOn October 22, 2020, the Holy See and the People’s Republic of China announced a renewal of their two-year agreement regarding the appointment of bishops for another two years. The deal had previously symbolized a monumental shift in relations between the Vatican and the Catholic Church in China, and its renewal raises questions and concerns about the future of Vatican relations with East Asia.\nSince the establishment of the state-run Chinese Patriotic Catholic Association in 1957, China’s Catholics, numbering approximately 12 million, have been split between the government-ordained churches and the underground and unofficial churches that remain outside the government’s reach. During this period, the Vatican maintained links with the underground churches and approved their clergy, while refusing to recognize the State-appointed bishops in the Chinese Patriotic Catholic Association and excommunicating their bishops. The 2018 accord, which has never been released in writing, gave the Pope a role in approving bishops, shortlisted by Beijing, for the State-run church. As a price for Papal sanction of the official church, the Vatican has encouraged the appointment of state-approved bishops to previously “underground” dioceses — a move some call a “selling out” of the faithful.\nThe Vatican insists that its agreement with China, and its subsequent renewal, is “purely ecclesiastic and pastoral in nature, not political.” Its primary objective was for the entirety of the Catholic faithful in China to have bishops in “full communion with the Successor of Peter” and settle the nature of the relationship between the Chinese Patriotic Catholic Association and Rome. The Holy See’s official statement praised the initial application of the Agreement as positive, and stated, “The parties intend to pursue an open dialogue for the benefit of the life of the Catholic Church and the good of Chinese people.” In recommitting to the agreement, the Vatican indicates that it believes it is on the right path to healing the fractured Church. There are 40 dioceses without formal leadership, and over one hundred bishop appointments need to be approved. The Vatican also expects that formalization and legitimacy for the unified Catholic Church will lead to improvements in daily life for Catholics in China, who face ever-mounting persecution. It is also spiritually significant for Chinese Catholics to be in unity with the Pope, and be accepted within the broader global church.\nThat China has given this influential foreign government a say in choosing leaders is a meaningful concession, considering how closely the government guards its domestic affairs. In a time of rising hostility among the international community towards China, this deal is arguably a diplomatic win for the Communist Party and a boon to its public image. A more cynical view might argue China has obtained religious legitimacy for its “sinification” of the Catholic faith. Cardinal Joseph Zen, former Bishop of Hong Kong, strongly opposed the deal and its re-signing — even travelling to Rome to plead his case. In his view, both the official and unofficial churches will be weakened by the deal, as the Chinese Patriotic Catholic Association is legitimized while the underground church is abandoned. Since the initial signing, the Vatican has not appointed bishops to any of the underground churches, while approving several State-approved candidates to the Patriotic Church. The Holy See’s willingness to negotiate with Communist China is a marked departure from previous Papal administrations. Zen attributes part of this pivot to Pope Francis’ Latin American background, where leftists advocated for the poor and opposed the persecution of Christians. In the broader picture, Zen believes the deal is a step towards “re-establishing diplomatic relations [between the PRC and Holy See],” which he believes to be misguided by virtue of being “political, not religious.”\nThe relationship between the Catholic Church and worldly political authorities has always been a delicate balance between the practical and the principle. Catholic social teaching affirms that “every civilized community must have a ruling authority…and this authority has God as its author.” This authority, however, “must guarantee community life without usurping the free activity of individuals and groups.” Herein lies the theological dilemma facing Catholic leadership in the face of a broken world; to what extent should the Pope work with countries that are avowedly opposed to Christian values and teachings? Unity and spiritual communion both within China and with Rome is certainly a laudable objective for the Catholic Church, but it may be too early to tell whether this agreement will deliver that result. Ever cognizant of the fragile relationship between the Church and political authorities, Pope Francis has had to walk a fine line in shepherding his flock. In a letter to Chinese Catholics at the time of the 2018 deal, Pope Francis wrote they should be “good citizens, loving their homeland and serving their country with diligence and honesty [….] At times, this may also require of them the effort to offer a word of criticism, not out of sterile opposition, but for the sake of building a society that is more just, human, and respectful of the dignity of each person.”\nIf the renewal of the 2018 agreement is truly emblematic of rapprochement between China and the Holy See, there are significant geopolitical concerns at stake. The Vatican is the last European government to recognize the Republic of China (Taiwan), and despite Papal assurances to the Taiwanese that they will continue recognition, it remains a significant bargaining chip the Vatican could use in further negotiations with the Mainland. Hastily switching recognition from democratic Taiwan (ROC) to the Mainland (PRC), where Catholic clergy remain imprisoned, may signal a weakness in the moral legitimacy of the Church. Only seventeen countries recognize Taiwan’s government, and a dissolution of relations by the Pope and the one billion followers he represents would be a significant political and moral blow to the island. While it may be tempting for the Vatican to offer this diplomatic coup in exchange for needed religious-freedom reforms in China, the Catholic Church needs to keep the balance between practical and principle in mind.\nPerhaps Pope Francis has made a fatal geopolitical and spiritual error in trying to legitimize the state-run church; maybe Chinese Catholics will successfully keep their faith and freedom, and render unto Xi what belongs to Xi. In any case, the success or failure of the 2018 clerical agreement will be crucial in determining the future for global Catholicism, Taiwanese legitimacy, and religious freedoms in China.\nEdited by Max Clark", "pred_label": "__label__POS", "pred_score_pos": 0.5043842792510986}
{"content": "Correlating Culture to Corporate Success\nTawnya Starr’s presentation, “Culture Shock: Wake up your Business with the Right Culture,” discussed strategies for companies to improve their internal culture among their employees and the culture they develop with their customers. Starr, president of PrinterPresence (Booth 4058), shared some of the practices that have been effective for her company, a provider of website solutions for the printing industry. She outlined three steps to building a sustainable culture with both employees and customers.\nDeveloping a strong internal culture, Starr said, stems from the development of strong corporate values. She recommended that companies make a concerted effort to move beyond the typical values often found in many organizations and discover the values that make the most sense for their organization. To discover the right values for a company, Starr explained it should check five specific boxes:\nIt is distinguished? Are we obsessed with it? Will it outlive us? Can we actually live this value every day? Would we sacrifice money to protect it?\nStarr noted that once a company has established its core values, it’s important to hire with these values in mind, rather than hiring based on skill and then teaching values.\nThe third step to creating a strong culture that Starr outlined is living these values every day. She recommended that companies post them throughout their facilities to ensure they’re instilled in the minds of all employees on a daily basis.", "pred_label": "__label__POS", "pred_score_pos": 0.989990770816803}
{"content": "LEWISTON, Idaho - An officer with the Transportation Security Administration (TSA) at Lewiston-Nez Perce County Airport (LWS) discovered a loaded firearm Monday morning at the security checkpoint during routine screening of carry-on baggage.\nThe Transportation Security Officer (TSO) found the firearm around 6:15 a.m. in the carry-on bag of a male passenger ticketed for travel to Salt Lake City International Airport. The firearm - an American Arms .22 Magnum - was loaded with five rounds of ammunition.\nWhen the TSO saw the image of a firearm on the X-ray screen, the Lewiston Police Department (LPD) was immediately notified and responded to the checkpoint. LPD confiscated the firearm and the passenger was allowed to continue to his flight.\n“This incident is yet another reminder for all passengers headed to the airport - make sure you know what is in your luggage,” said TSA Federal Security Director for Idaho Andy Coose. “Firearms traveling in the cabin of an airplane pose a significant hazard to the aircraft and to passengers. Firearms in carry-on luggage discovered at the security checkpoint can result in police action, delays in screening and fines or prosecution. I urge all travelers to look carefully and know what they are bringing in their bags\nbefore heading to the airport.”\nThis is the first firearm TSA has discovered in carry-on baggage at LWS in 2017. No firearms were discovered in carry-on baggage at LWS in 2016. However, TSA officers discovered a total of 22 firearms at Idaho airports in 2016 including 18 at the Boise Airport, two at Joslin Field Magic Valley in Twin Falls and two at Idaho Falls Regional Airport.\nNationwide in 2016, TSA found 3,391 guns in carry-on bags at airport security checkpoints. In 2015, TSA officers across the country detected 2,653 firearms in passengers’ carry-on bags.\nFirearms, ammunition, firearm parts and realistic replicas of firearms are always prohibited in carry-on baggage. However, these items can be transported in checked baggage provided the traveler declares them to the airline during the ticket counter check-in process.\nFirearms in checked baggage must be unloaded and stored in a locked, hard-sided container. TSA urges passengers to contact their airline for specific firearm and ammunition policies and to check local laws related to the carrying and transport of firearms.\nIn addition to facing local or state criminal charges, TSA reserves the right to levy a civil penalty of up to $7,500 for bringing a dangerous weapon like a firearm to the checkpoint. Each penalty is evaluated on a case-by-case basis.\nTSA reminds passengers to be aware of the contents of their carry-on bag prior to coming to the security checkpoint. TSA has multiple resources available to passengers to help them determine whether an item is permitted in carry-on baggage, checked baggage or not at all. For more information, visit the prohibited items page on tsa.gov or use TSA's app -\nmyTSA.\nAdditional traveler information specifically related to the commercial air transport of firearms and ammunition can be found on the transporting firearms and ammunition page on tsa.gov.", "pred_label": "__label__POS", "pred_score_pos": 0.7059282660484314}
{"content": "Abstract\nIntelligence has consistently been recognized as a robust correlate of health, life success, and behavior. Evidence also suggests that intelligence may contribute to another key correlate of behavior: self-control. The current study builds on recent work in this area by examining the association between intelligence and self-control across multiple raters and when accounting for potential confounding influences not accounted for in prior research. Results based on a national sample of U.S. children indicates that higher scores for intelligence are associated with more self-control in both cross-sectional and longitudinal models, even when accounting for prior self-control, child executive functioning, maternal intelligence, and maternal self-control. Moreover, the association persisted across both teacher and mother ratings of child self-control. As such, these findings support and extend prior work examining the nexus between intelligence and self-control, and may explain why both traits are important for understanding success across a host of life outcomes in humans.\nKeywords Adolescence Childhood Intelligence SECCYD Self-control ASJC Scopus subject areas Experimental and Cognitive Psychology Developmental and Educational Psychology Arts and Humanities (miscellaneous)", "pred_label": "__label__POS", "pred_score_pos": 0.9792068004608154}
{"content": "AAFP Urges CMS to Safeguard Continuity of Care for Seniors AAFP, other groups concerned about commercial entities undermining value of annual wellness visit\nMONDAY, May 18, 2015 (HealthDay News) -- In a letter to the Centers for Medicare & Medicaid Services (CMS), the American Academy of Family Physicians (AAFP) and other organizations emphasize the importance of encouraging Medicare beneficiaries to engage with their primary care physician in an annual wellness visit.\nNoting that the annual wellness visit aims to keep senior patients healthy by allowing them to engage with their primary care physician on an annual basis for prevention and early detection of illness, the AAFP and six other organizations expressed concern that some commercial entities were subverting the benefit and misleading patients by offering additional services.\nIn their letter to the CMS, the organizations emphasize the importance of continuity of care and note that patients may be denied some of the benefits of the annual wellness visit if the provider has no prior relationship with the patient or intent of continuing care for the patient after the annual wellness visit. In addition, the patient's primary physician may not know that the patient has received an annual wellness visit from a distinct entity until after the fact. Some of these entities engage in direct-to-consumer marketing, and the advertisements are misleading for consumers.\n\"We would like CMS to engage with our organizations in a conversation about creative ways to ensure that the benefit of the annual wellness visit is preserved rather than perverted,\" the letter reads.", "pred_label": "__label__POS", "pred_score_pos": 0.8999097943305969}
{"content": "The laws of Texas define sexual harassment as any unwelcome conduct of a sexual nature, including acts of either a verbal or physical nature. Sexual advances, creating a hostile work environment that is blatantly sexual in nature, and sexual advances are some of the more frequent types of sexual harassment amongst employers.\nHow does Texas Law Prohibit Sexual Harassment?\nFirst, Lake Jackson employers can be required to establish company policies that specifically address sexual harassment in the workplace. These must be posted in a visible area such as a break room. These policies may include contact information for an employee to report sexual harassment, the procedure for handling such claims, and the corrective measures for when a claim is proven.\nThere are also agencies which are appointed by federal and Texas law for the specific purpose of handling sexual harassment cases. Such agencies have the authority to investigate work sites to determine if the complaints they receive in Lake Jackson are true. Employers are also prohibited under these laws from taking action in retaliation against an employee who has claimed sexual harassment, such as firing them or denying them a promotion.\nHow can a Texas attorney help?\nInvestigating and showing a sexual harassment claim might be difficult without consulting someone with expertise in the relevant laws. Federal investigators are often very overworked. Accordingly, hiring a lawyer in Lake Jackson might be the best way to ensure that your claim is filed within the deadlines specified by Texas for sexual harassment matters.", "pred_label": "__label__POS", "pred_score_pos": 0.7748271226882935}
{"content": "Abstract\nSmoking prevalence among junior enlisted members of the United States armed forces significantly exceeds that of civilians. Furthermore, nearly 40% of junior enlisted who smoke reported they initiated smoking after joining the military. Although the tobacco industry has attempted to develop messages that encourage military members to use tobacco, no research has examined messages that would counteract industry messages and effectively discourage military members from using tobacco. This study conducted 24 focus groups on four Air Force and two Army installations (N=189 personnel) to discover effective messages that discourage tobacco use among junior enlisted personnel. Four message themes were identified that hold promise for tobacco control efforts in the military: (a) smoking harms one's ability to positively influence others, (b) smoking increases the chance a military member will be discharged from the military prematurely, (c) smoking lowers readiness to fight and win wars, and (d) smokers are not as productive as other military personnel. In contrast, messages focusing on manipulation by the tobacco industry and the health effects of tobacco use were not strongly supported by military personnel.", "pred_label": "__label__POS", "pred_score_pos": 0.997734010219574}
{"content": "Abstract\nParotid secretory protein (PSP) and palate-lung-nasal epithelium clone (PLUNC) are novel secretory proteins that are expressed in the oral cavity and upper airways. Both proteins are related to bactericidal/permeability increasing protein (BPI). Cationic peptides derived from BPI exhibit anti-inflammatory activity. To test if PSP (C20orf70 gene product) also contains anti-inflammatory peptides, we designed 3 cationic peptides based on the predicted structure of PSP and known active regions of BPI. Each peptide inhibited the lipopolysaccharide (LPS)-stimulated secretion of TNFα from RAW 264.7 macrophage cells. At 200 μg/mL, the peptide GK-7 exhibited inhibition similar to that achieved with 10 μg/mL of polymyxin B. PSP peptides directly inhibited the binding of LPS to LPS-binding protein. The cationic peptide Substance P had no inhibitory effect in these assays, confirming the specificity of the PSP peptides. These findings suggest that PSP peptides can serve as templates for the design of novel anti-inflammatory peptides.\nKeywords C20orf70 Cationic peptides Endotoxin Inflammation Lipopolysaccharide PLUNC Saliva", "pred_label": "__label__POS", "pred_score_pos": 0.7960542440414429}
{"content": "LRN’s presence in Canada aims to support our partners in the region with their ethics and compliance programs by providing inspiring solutions that help people navigate complex legal and regulatory issues.\nMotivating people to do the right thing is the essence of principled performance. It is about inspired rather than required behaviour—living principles, not simply following rules. It is about doing the next right thing and not just the next thing right. Ultimately, principled performance leads to healthier, profitable organisations.\nIn partnership with LRN, companies need not choose between living principles and maximising profits, or between enhancing reputation and growing revenue: all are products of principled performance. Our offerings mitigate the risk of costly ethical lapses and compliance failures while building trust and earning the company a reputation for lawful and ethical conduct.\nLRN is the trusted long-term partner to more than 400 organisations, including some of the most respected and successful businesses in the world, which has enabled us to create an active and growing community with a common interest. Together we acquire and disseminate proven strategic and tactical insights and develop solutions based on current, real-world experiences.\nWill you be joining us on this mission?", "pred_label": "__label__POS", "pred_score_pos": 0.7665769457817078}
{"content": "Emotion-focused mindfulness therapy (EFMT; Gayner, 2019) welcomes into meditation and therapeutic encounters the processes that weave consciousness and deepen experiencing, including perception, bodily and sensory experience, feelings, imagery, thinking, needs and action tendencies. Meditators cultivate gentleness and participatory curiosity, exploring how to navigate experiencing oriented to their values and what they find works for them. People are free to feel inclined, consider the future, remember, and reflect on experience while meditating. From an EFMT perspective, the only time we have to experience and reflect on planning and remembering\nis the present moment and to not include them in meditation and therapy would be to exclude central aspects of being human.\nMost of us spend a lot of time alternating between being in our heads disconnected from feelings or being too immersed in and buffeted by stressful emotions and thoughts (Gendlin, 1981; Teasdale, 1999). In contrast, mindful experiencing brings us alive to our implicit feelings in a way that transforms our relationship with experience (Teasdale, 1999). This enables meditators to turn toward and\ndecentre from difficult thoughts and feelings. “Decentering” means being able to experience thoughts and feelings as events in consciousness rather than as direct, unmediated truths about self, others and the world (Safran & Segal, 1990). Mindful experiencing creates optimal conditions for experiential and emotional processes that enable us to arrive at and make sense of our feelings, integrate feeling and thinking, resolve internal conflicts and unfinished business, and better navigate our lives, cultivating growth and a fulfilling life. However, mainstream clinical mindfulness neither specifies nor encourages experiential and emotional processing in meditation, emphasizing instead staying in touch with implicit feelings (Kabat-Zinn’s “bloom of the present moment” (2010 [1994]), while decentering from and letting go of difficult thoughts and emotions. In contrast, emotion-focused mindfulness therapy (EFMT) uses emotion-focused therapy (EFT; Greenberg, 2015 [2002]; Elliott, Watson, Goldman & Greenberg, 2004; Elliott & Greenberg, 2007) to provide meditators with the option to not only open into the ‘bloom of the present moment,’ but also to make deeper sense of it and respond differentially, integrating experiential and emotional processing into mindfulness meditation and therapeutic encounters.\nEFMT emerged out of exploring how to integrate self-compassion more deeply into mindfulness to better help gay men living with HIV suffering from issues associated with internalized stigma such as harsh self-criticism, difficulties generating self-warmth and social isolation, as well as the related effects of adverse childhood events so prevalent for them. It is based on the view that “wise compassion is empathic, involving not only feeling moved by suffering.., wishing it be alleviated… and wanting to help, but also the ability to follow thoughts and feelings in oneself and others with kindness. Empathy is a fundamental relational skill and a key aspect of emotional intelligence (Elliott, Watson, Goldman & Greenberg, 2004, p. 103)” (Gayner, 2019).", "pred_label": "__label__POS", "pred_score_pos": 0.6340621709823608}
{"content": "Hannah Garrow, LI Policy and Influencing Manager for Scotland and Northern Ireland, reflects on a new initiative in Scotland to put landscape at the heart of policy- and decision-making\nOn 25 April 2019,\nScotland’s Landscape Alliance held its official launch event at Our Dynamic Earth in Edinburgh. Over 90 individuals representing 65 organisations with an interest and involvement in landscape design, management and stewardship in Scotland came together to discuss the future of landscape policy.\nThe Alliance has been coordinated by Landscape Institute Scotland (LIS), the Scottish branch of the LI, in partnership with the National Trust for Scotland (NTS). It responds to the need for\nmore joined-up thinking to embed landscape approaches to policy-making and delivery.\nThe new initiative follows the publication of the branch’s advocacy document Landscape for Scotland in November 2017. The document set out the different ways in which landscape can contribute to the Scottish Government’s national outcomes and current priorities as set out in their Programme for Government 2018/19. A debate at the Scottish Parliament in June 2018 further emphasised the need for a strategic forum to address landscape issues, which often fall between the cracks in current policy-making.\nWhat’s significant about this approach is the effort to get a\nwide range of voices into the room from the multiple perspectives and aspirations for Scotland’s land and to break down the barriers of silo-based working. It was fantastic to see such a broad variety of interests represented from design and placemaking, nature conservation, public health, research, urban regeneration and rural protection. There was a real buzz about being involved at the beginning of what could be a significant step for a more inclusive, balanced discussion about the future of landscape in Scotland.\nIn terms of next steps, attendees at the event were asked to sign up to a series of working groups which will discuss landscape-related issues across three key themes – resilience to environmental challenges, creating healthy places and land-use and the economy – with a view to co-producing a set of recommendations for strengthening landscape policy and implementation.\nResearch commissioned in advance of the launch event by LIS and NTS emphasises the importance and need for such a move. Despite efforts to embed the principles of the European Landscape Convention, it demonstrated the challenges of defining landscape and the need to see landscape not just as something to protect, but as a catalyst for a wide range of social, environmental and economic outcomes. It also highlighted the difficulties of resourcing and managing change, ambitions for more just and democratic governance and and the significance of wider global influences like climate change.\nRachel Tennant, Chair of the LIS, who has been one of the key drivers behind the creation of the Alliance, said ‘This is the start of a public conversation to collectively agree on how Scotland’s landscapes can be healthy, biodiverse, beautiful, economically useful and embedded in communities. The Alliance will consider what we need to do to ensure we deliver these public benefits for the 21st century and beyond.’", "pred_label": "__label__POS", "pred_score_pos": 0.60506671667099}
{"content": "Building resilience of critical infrastructure requires decision-makers working in different industry sectors to understand ‘what’ can be done, ‘why’ it should be done, and ‘how’ to put it into practice.\nOur work to date has told us that key stakeholders are often either unaware of the value that resilience can bring or are constrained by a lack of resources or support in terms of how to embed and enhance resilience.\nThis primer is a brief document introducing the elementary principles of resilience relevant to the electric utilities sector and is part of a body of knowledge, tools and approaches that the Resilience Shift is producing, funding, and curating, intended to help those responsible for the financing, planning, design, delivery, operation and maintenance of critical infrastructure systems to shift practice.\nOur vision is to contribute to a common understanding across critical infrastructure sectors of what contributes to resilience and how it can be achieved in practice.\nBuilding resilience into your infrastructure systems, across your value chains, will allow you to prevent or mitigate against shocks and stresses that you identify, and to respond better to those events that you can’t predict or avoid.\nWe’re delighted to have supported the team at Wood in producing this primer.\nPublication date: 11 July, 2019 Authors: Wood Environment and Infrastructure (E&IS) (Peter Hall, Rebecca Vanderbeck, Michael Triano).The authors would like to thank Mantle314 Inc. (Laura Zizzo, Anton Tabuns) for their expertise in the development and review of this report.", "pred_label": "__label__POS", "pred_score_pos": 0.5076001286506653}
{"content": "COMFORTING CUBBIES\nPreK–K\nChildren's cubbies are special places where personal belongings can be stored, treasures can be displayed, and solace can be found. Try these ideas to make cubbies a source of comfort and support for children.\nEncourage children to bring a family picture to school and display it in a place of honor in their cubbies. Invite children to decorate shoeboxes that will serve as treasure boxes for items they might gather on a class walk, find on a field trip, or bring from home. Children can keep their treasure box on top of or inside their cubbies. A glance or two at \"special treasures\" often serves as a quick source of comfort and pleasure. Ask children to help you to line their cubbies with contact paper in soft, pastel colors or patterns of their choice if your school allows. If this is not possible, you might try lining cubbies with children's drawings and paintings. Keep a stack of notecards on hand so that you can create soothing messages to children who may be having a difficult day. You might attach stickers to the cards, write simple messages that you can share at the end of the day, or draw a happy, smiling face with the child's name at the top of the card and your own at the bottom. Place the notes in children's cubbies, inviting them to \"check their cubbies\" when some relief is needed. Make cubby-size pillows as a class project. Store the pillows in children's cubbies so that they can be snuggled with when needed. Allow children to store their favorite blanket or \"lovey\" from home in their cubby. Just seeing their special object and knowing that it is available for them at the end of the day is comforting and reassuring.", "pred_label": "__label__POS", "pred_score_pos": 0.5260576009750366}
{"content": "Salicylic acid helps to slow the sloughing off of dead skin cells that can clog pores and cause blackheads.\nContinue Learning about Nonsteroidal Anti-inflammatory Drugs\nImportant: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.", "pred_label": "__label__POS", "pred_score_pos": 0.8171688318252563}
{"content": "It's painful to contemplate, but being hundreds of pounds overweight can be a true death sentence -- or, worse, it can sentence you to a kind of living death. In this video, Dr. Oz lays out the grim reality for a group of severely obese women. Then he issues a challenge.\nContinue Learning about Obesity\nImportant: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.", "pred_label": "__label__POS", "pred_score_pos": 0.7504516839981079}
{"content": "SARS-CoV-2 evades immune detection in alveolar macrophages.EMBO Rep. 2020 Oct 28 [Online ahead of print]ER\nRespiratory infections, like the current COVID-19 pandemic, target epithelial cells in the respiratory tract. Alveolar macrophages (AMs) are tissue-resident macrophages located within the lung. They play a key role in the early phases of an immune response to respiratory viruses. AMs are likely the first immune cells to encounter SARS-CoV-2 during an infection, and their reaction to the virus will have a profound impact on the outcome of the infection. Interferons (IFNs) are antiviral cytokines and among the first cytokines produced upon viral infection. In this study, AMs from non-infectious donors are challenged with SARS-CoV-2. We demonstrate that challenged AMs are incapable of sensing SARS-CoV-2 and of producing an IFN response in contrast to other respiratory viruses, like influenza A virus and Sendai virus, which trigger a robust IFN response. The absence of IFN production in AMs upon challenge with SARS-CoV-2 could explain the initial asymptotic phase observed during COVID-19 and argues against AMs being the sources of pro-inflammatory cytokines later during infection.\nPub Type(s) Language PubMed ID Citation EMBO Reports,2020, pp. e51252. EMBO Rep. 2020. EMBO Reports, e51252. https://doi.org/10.15252/embr.202051252 EMBO Rep.2020 Oct 28;e51252. PubMed PMID: 33112036.", "pred_label": "__label__POS", "pred_score_pos": 0.9204264879226685}
{"content": "Kelly Carr wants to destroy barriers.\nThat’s why her research as a PhD student at the University of Windsor has worked to showcase the strengths of people with disabilities to combat the negative stigma that often follows them throughout their lives.\nCarr’s research is broken into three phases and examines how people with an intellectual disability or autism spectrum disorder (ASD) participating in a physical exercise program, meaningful employment and elite sports can influence opinion.", "pred_label": "__label__POS", "pred_score_pos": 0.7703711986541748}
{"content": "U.S. Coronavirus Deaths Projected to Surpass 200,000 by October\nOver one million people and counting have tested positive for coronavirus in the United States.\nAs the country continues to reopen, a report from the University of Washington predicts the death toll from the virus can reach 201,129 by October 1.\n“It is increasingly clear that COVID-19’s toll will extend beyond the summer months in the Northern Hemisphere, and current epidemics could easily worsen as the Southern Hemisphere nears its winter season,” the university’s Institute for Health Metrics and Evaluation (IHME) said.\nThe University of Washington's model also showed that Florida could be one of the hardest-hit states with 18, 675 deaths by October.\nThe university's findings are based on multiple factors and researchers note an individual's behavior can play a major role in how things actually pan out.\n\"We're making a forecast, clearly what individuals choose to do can moderate that forecast,\" IHME Director Dr. Christopher Murray told CBS News. \"If mask use starts to go back up in states where it's not very high, that is likely to be very helpful. And if people avoid contacts with people outside their household... that will also moderate the effect.\"\nHealth officials across the nation have warned Americans about a second wave of coronavirus cases.\nNow, as stay-home orders relax and reopening plans advance to later phases, some states are seeing a rise in COVID-19 infections.\nAt least 19 states are currently experiencing a trend of new increasing cases. One of these states, Arizona, is bracing for impact, with officials urging hospitals to activate emergency plans. Dr. Cara Christ, the state's Director of Health Services, has asked that hospitals \"be judicious\" in elective surgeries to guarantee bed capacity.\nWhile 24 U.S. states are trending downward in their COVID rates, seven states remain steady. Additionally, since Memorial Day, hospitalizations for the virus have increased in at least 12 states, including Alaska, Arkansas, Arizona, California, Kentucky, Mississippi, Montana, North Carolina, Oregon, South Carolina, Texas and Utah.\nWhile the US remains at the epicenter of the coronavirus crisis, back in May, the country surpassed the shocking milestone of over 100,000 deaths from the virus.\nAs of Wednesday, there have been at least 116,000 coronavirus deaths in the United States since the begining of the pandemic, according to data from Johns Hopkins, reported Fox News.", "pred_label": "__label__POS", "pred_score_pos": 0.8259186744689941}
{"content": "You may experience severe pain, redness and swelling in and around the piercing site. Often, very often, a white fluid drains out of piercing. This must not be mistaken with pus, because it is lymphatic fluid that acts like a cleanser for dirt and bacteria. After a few days, yellowish crust forms, indicating that the piercing has started healing. However, it cannot be with every piercing. If proper care is not taken while piercing, it can lead to infections or if you do not take proper aftercare instructions, infections may develop. Infections are characterized with pus formation, bleeding, throbbing pain and bumps on piercing. Sometimes, piercing may produce foul smell.\nA professional piercer must advise a person about proper piercing care. He must execute some precautionary steps while piercing. He must use sterilized instruments and wear clean gloves while piercing. Apart from these, a person who gets his ear pierced must follow the following steps to avoid cartilage infection.\nDo not touch cartilage piercing with the naked hands. Dirty hands is the access point for bacteria to enter the piercing. Use a disinfectant soap to wash the hands properly. Never play with piercing jewelry. Fingering the piercing jewelry with dirty hands cause infection. While putting on clothes, take proper care of piercing. Use an antiseptic lotion to clean the piercing twice a day, till it heals completely. You can soak jewelry in alcohol solution for disinfecting it. Never apply hydrogen peroxide, tea tree oil or alcohol directly on piercing. Don’t change the jewelry frequently in the initial months. Always keep your hair clean and do not keep the public telephone receiver on the ear directly.", "pred_label": "__label__POS", "pred_score_pos": 0.9622692465782166}
{"content": "Microstructural Differences Detected on Brain MRI in PANS Increased diffusivity seen in deep gray matter in pediatric acute-onset neuropsychiatric syndrome\nTHURSDAY, May 7, 2020 (HealthDay News) -- Children with pediatric acute-onset neuropsychiatric syndrome (PANS) have cerebral microstructural differences in multiple brain structures, including the deep gray matter structures, according to a study published online May 4 in\nJAMA Network Open.\nJimmy Zheng, from the Stanford University School of Medicine in California, and colleagues conducted a case-control study focusing on the evaluation and treatment of children with PANS. A total of 60 consecutive patients who underwent diffusion-weighted magnetic resonance imaging (MRI) before immunomodulation from Sept. 3, 2012, to March 30, 2018, were reviewed for study inclusion. After exclusion of patients, 34 patients with PANS before treatment initiation were compared to 64 pediatric control participants.\nThe researchers identified a statistically significant difference in MRI parameters for patients with PANS and controls. Compared with controls, in patients, all assessed brain regions had statistically significantly increased median diffusivity. The most profound increases in diffusivity were seen for the deep gray matter (thalamus, basal ganglia, and amygdala), consistent with clinical symptoms of obsessions, compulsions, emotional dysregulation, and sleep disturbances. With respect to volume and cerebral blood flow, there were no statistically significant differences.\n\"The hypothesis that neuroinflammation is the underlying cause of acute-onset obsessive-compulsive disorder in PANS may explain the MRI diffusion differences in multiple brain structures observed herein, particularly the deep gray matter structures, such as the thalamus, basal ganglia, and amygdala,\" the authors write.", "pred_label": "__label__POS", "pred_score_pos": 0.9637252688407898}
{"content": "Supply Chain Management: An Empirical Study of its Impact on Performance Abstract\nTotal quality management, supply base management, customer driven corporate policy, and other elements of supply chain management are frequently cited as strategic options to achieve competitive success in the 1990s. However, attempts by companies to implement these options have not been universally successful and have in many cases failed to yield the desired results. This study presents details of a survey carried out to determine whether particular quality management, supply base management, and customer relations practices can impact corporate performance. In addition it examines the impact analyzing the competitive environment has on performance. Regression models identify several factors that directly and positively impact corporate performance. These include the extent to which companies analyze the strategies of competitors and determine future customer requirements, and the commitment they have to evaluating performance throughout the supply chain.\nThis paper has been withdrawn.", "pred_label": "__label__POS", "pred_score_pos": 0.6148682832717896}
{"content": "In this video, ecologist Tony Sinclair takes us through the steps of how he uncovered that the eradication of an infectious disease in cattle led to a boom in the Serengeti’s buffalo and wildebeest numbers.\nThis film explores the species-area relationship, a general ecological rule that describes how the number of species in a habitat changes with area, and shows how it has been applied to the conservation of protected areas.\nThis data-driven activity accompanies the video Selection for Tuskless Elephants. It engages students in analyzing data to make evidence-based claims about the occurrence of tusklessness in elephant populations.", "pred_label": "__label__POS", "pred_score_pos": 0.9461845755577087}
{"content": "Institute of International Politics and Economics (IIPE) and Hanns Seidel Foundation organised a webinar dediated to the position of the Western Balkans during the new mandate of the European Commission in the context of the Covid-19 pandemic. Following the greeting speeches of the IIPE representatives and the introductory lesson of Dr Klaus Fiesinger, the Hanns Seidel Foundation`s regional director for Southeast Europe, on EU support to reform processes in the Balkan countries, presentations within the two thematic panels ensued. The participants discussed the limitations and challenges in the European integration process in the Western Balkans and the consequences of the pandemic, but also touched upon potential changes in trans-Atlantic relations following the 2020 USA presidential elections. Presenters agreed that the Covid-19 pandemic significantly impaired the development perspective of the Western Balkan region, as well as the EU role in that area, especially during the first months of the pandemic crisis. Prof. Dejan Jović, Faculty of Political Science at the University of Zagreb, stated that, among other things, the pandemic crisis also contributed to the rise of sovereignist logic and disruption in terms of enjoying the rights and “EU freedoms”. Lecturer at the Masaryk university in Brno, Dr Vladimir Vučković, deliberated on deficiencies of previous EU enlargement approach and pointed out that greater credibility of enlargement policy is needed. IIPE researcher Dr Miloš Petrović expressed hope that the European Union’s revised enlargement methodology might provide an impetus on the Western Balkans’ EU path and somewhat reduce previous deficiencies. Prof. Nikolaos Tzifakis from the University of the Peloponnese identified that the Western Balkans remained significantly vulnerable in crisis situations and that previous reactions left little hope towards articulating a common regional approach in battle against the Covid-19. Dr Ritsa Panagiotou, senior research fellow at the Centre for planning and economic research in Athens, considered prospects for realization of EU financial programs such as the Economic and Investment Plan, which might provide significant economic boost to the Western Balkan development. Dr Ivana Radić Milosavljević, Lecturer at the Faculty of Political Science at the University of Belgrade, noted that the processes initiated by the European Union raised numerous questions, including the possibility for gradual and selective integration, but also referred to overcoming an old problem – exploiting the Balkan candidates’ accession process for addressing the bilateral disputes with neighboring countries. Prof. Joseph Michael Gratale from the American College of Thessaloniki held a lecture on the topic of political communication and so-called “Twitter diplomacy” which characterized the American presidency of Mr Donald Trump. As part of the discussion, the participants deliberated on negative effects of the pandemic for the international democratic development, as well as about boundaries to EU influence in its geographic neighborhood.\n1 of 8", "pred_label": "__label__POS", "pred_score_pos": 0.6913015842437744}
{"content": "The past few months have certainly been challenging for businesses all over the UK - from start-ups to established industry leaders. Organisations have found themselves adapting to the demands of a remote workforce virtually overnight, deploying communications solutions to enable their teams to engage with both each other and their customers. While it's true that this technology has been available for a while now, it has never been deployed at this scale before. This has presented a range of challenges when it comes to infrastructure, but these are only part of the picture.\nWith any new technological deployment, there is always a period of adaptation, particularly when teams - or in certain cases, whole sectors - have well-established ways of working that they are hesitant to change. Sometimes this is a question of compliance, where sectors have highly specific requirements regarding the handling and protection of sensitive data. Generational differences are also common, where there's a disparity between the older generation, who're accustomed to the traditional office environment, and the up-and-coming workforce, who expect their employers to offer a certain amount of flexibility with regard to remote working.\nIn light of this, it's no surprise that the overall uptake of remote working over the years has been relatively slow. However, the current pandemic has largely pushed such concerns into the background, as organisations have adopted these practices out of sheer necessity, in order to remain as close to business-as-usual as possible. We've seen this first-hand at Exponential-e, both with our own teams and those of our customers.\nConsider the following statistics from our recent employee survey:\nAllowing teams to experience the potential benefits of remote working for themselves has led to a massive cultural shift in the way we think about our workspaces and infrastructure. Indeed, we are already hearing from leaders and stakeholders within our customers' organisations who are reconsidering the amount of physical office space they will require in the post-COVID-19 landscape, having witnessed the upsurge in productivity and identified the potential cost savings.\nOf course, none of this would have been possible without the technological backbone in place to support organisations' explorations of remote working. Beyond the UC solutions used to connect teams and customers, this has involved taking full advantage of the agility and scalability of Cloud solutions, along with security solutions that ensure critical data remains secure and is handled in a compliant manner, regardless of where teams and customers are located.\nIn this way, we're seeing technology supporting cultural shifts, which - in turn - are driving new technological innovations. There's no doubt that the workforce has evolved in recent months, but there is still much to be done if we are to establish a new standard of best practice around remote working and ensure teams can access the right tools, infrastructure and support as their requirements evolve.\nThis will require close collaboration between organisations and their IT partners, but the potential for enhancing productivity, morale and cost savings at all levels is enormous. We look forward to seeing what new developments the coming months hold, as we emerge from lockdown and settle into the 'new normal'.\nJoin our webinar on Tuesday 16\nth June at 14:30 to learn more about the challenges faced across all sectors when shifting to a remote workforce, and how we can be prepared moving forward to the future with a distributed workforce model and the 'new normal'. Register here to join our Managing Director, Mukesh Bavisi, discuss with our panellists Chris Christou, Director of Engineering, Mark Belgrove, Head of Cyber Consultancy, Afshin Attari, Director of Public Sector and Unified Communications and Jonathan Bridges, Chief Innovation Officer, discuss this in more detail.", "pred_label": "__label__POS", "pred_score_pos": 0.6547738909721375}
{"content": "Download:\nThis paper seeks to address the issue of skills development for youth-at-risk, including the economically vulnerable and the socially excluded. A micro-level approach is used to identify good examples of training programmes and projects that have successfully identified and targeted vulnerable young women and men and implemented and evaluated their initiatives.", "pred_label": "__label__POS", "pred_score_pos": 0.9712521433830261}
{"content": "The 8th of July marked a very important milestone for the SPEECHIE Project team. The dissemination event, entitled\n“Technology for Bilingual Children with Developmental Language Disorders (DLD): Where do we stand?” was held at Esplora Interactive Science Centre, Kalkara, and Olly Speaks was officially showcased to the public.\nThe aim of this event was to disseminate the scientific results obtained from the\nSPEECHIE project, coordinated andfunded by the Malta Council for Science and Technology (MCST) under the Technology Development Programme 2016 and also to gather more feedback on the device itself Olly Speaks, from a widespread spectrum of stakeholders. Distinguished guests from government and academia attended the event. MCST falls under the Honourable Silvio Schembri, Parliamentary Secretary for Parliamentary Secretary for Financial Services, Digital Economy and Innovation.\nDevelopmental Language Disorders (DLD) in children is often attributed to various factors including intellectual disability, autism and hearing loss. Children with DLD are often faced with social communication, behavioural, educational and vocational difficulties. Although bilingualism does not cause DLD, such disorders can be complicated when children have bilingual or multilingual exposure, which is a common occurrence worldwide. This has particular relevance to the language-learning context of Maltese children. DLD in children can often be addressed by a customised intervention programme drawn up by a professional speech-language pathologist (SLP) on the basis of assessment and regular review of the child’s speech and language skills. However, children often lose engagement when subjected to repetitive therapy activities and lengthy assessment procedures. This impinges on the effectiveness of intervention.\nWithinthis context, the\nUniversity of Malta and Flying Squirrel Games (FSG) Ltd. have joined forces todevelop a novel, multi-modal device, called Olly Speaks,to facilitate language therapy for children with DLD both within and beyond theclinical setting. Olly Speaks will bedeveloped as a smart therapeutic device that entices children to engage withthe designated exercises by creating a more rewarding and motivatingenvironment. Furthermore, it enablesSLPs to monitor the child’s progress and to carry out remote therapy. Due toits unique selling points, Olly Speakswill revolutionize the current practices to carry out speech and languagetherapy.\nTheidea behind\nOlly Speaks is subject toa pending patent application. The research team, led by Dr Ing. PhilipFarrugia, who is the originator of this idea, has completed a full workingprototype of the device. This prototype will be tested with children andrelevant stakeholders, including SLPs and guardians. A risk conformity assessment of the device was carried out abroad by a company which specialises in toydevelopment, with the aim of bringing Olly Speaks closer tomarket. Dr Ing. Philip Farrugia said “Ourlong term vision is to develop further OllySpeaks such that it caters for multiple bilingual scenarios, such asEnglish-German and Spanish-English. The research team strongly believes that Olly Speaks has a huge market potential.”\nThe Chairman of the Malta Council for Science and Technology, Dr Jeffrey Pullicino Orlando had words of praise for the consorstium, he said “it is indeed rather exceptional to come across the synergy and dynamics which define the SPEECHIE Consortium. The momentum generated by this level of ambition is pivotal to the mechanism behind the national R & I Programme FUSION, which is administered by the Malta Council for Science and Technology.\nThe Malta Council for Science and Technology continues to serve as a springboard for local Research and Innovation in Malta, a forum which already boasts a notable critical mass which I firmly believe can continue proliferate.”\nThe Pro Rector for Research at the University of Malta, Prof. Saviour Zammit stated that “Research is one of the three main missions of University life, the others being teaching and involvement in socioeconomic development, and is entrenched in the University of Malta’s vision, mission and belief statements. Our recently-published strategic document for the years 2020 to 2025, identifies eight strategic thrusts to strengthen the research pillar at the University of Malta. Funding is of the essence, and the University of Malta acknowledges the various MCST programmes that contribute significantly to the UM’s research budget and welcomes the recent peer review conducted by the European Commission’s Policy Support Facility further to a request by the Parliamentary Secretariat for Financial Services, Digital Economy and Innovation, which has identified the need to significantly increase national funding for bottom-up research and knowledge transfer in support of industry-academia collaboration.”\nThedevice\nOlly Speaks has already been showcased on variousoccasions, including Science in the City, Notte Bianca and the 17 th InternationalClinical Phonetics and Linguistics Association Conference (ICPLA),during which the utility of the device received many encouraging comments andpositive feedback. The SPEECHIE project would like to thank their sponsors Tek-Moulds Precision Engineering Ltd; Nestle; Invent 3D; ToyMagic and the Farsons Foundation for their support.", "pred_label": "__label__POS", "pred_score_pos": 0.6637576222419739}
{"content": "NCC significantly affects the majority of privately operated bizjets in Europe. What is required to achieve compliance?\nIn 2016, the EU raised the bar for ‘Non Commercial Complex’ aircraft registered in, or where their operators reside in, an EASA state. Even those N-registered aren’t exempt, if they are residents or have their principle place of business in the region.\nThis regulation significantly affects the majority of privately operated bizjets in Europe.\nEASA Part-NCC requires operators to adhere to the same requirements as commercial operators, however the rules are proportionate to the scale of the operation. Each operator, once compliant, must make a declaration to their NAA, to enable the regulator’s oversight programme.\nSo, what is required to achieve compliance?\nA management system. This will establish the structure of the operation, personnel, procedures, a safety system, and an audit programme. An Operations Manual. This will reflect the specifics of the operation, the aircraft, areas of operation, crew, training, and so on. A Minimum Equipment List. Based on the MMEL, but must be tailored to the operation and approved by the state of registry. A Continuing Airworthiness Management Organisation. The aircraft will be assigned to a CAMO approved by EASA, to manage the aircraft’s airworthiness for the operator.\nWhilst compliance will remain the responsibility of the operator, the complexities can make it a daunting prospect. For the uninitiated, it’s wise to contract qualified support to assist the process.\nMany technical writers are available to freelance a solution for an operator in need, albeit with varying degrees of success. The discomfort of a diligent SAFA ramp inspection is always best avoided, and onboard documents are an easy target.\nThe Signature Technicair CAMO based in Bournemouth in the UK, has a wealth of experience in delivering EASA Part-NCC solutions. For airworthiness management services, call +44 (0)1202 583403.", "pred_label": "__label__POS", "pred_score_pos": 0.7360436916351318}
{"content": "This document is a notice of dissolution of a partnership, which can be inserted into the relevant Government Gazette.\nUnder Australian partnership law, certain states and territories require a notice to be placed in the state or territory Government Gazette upon:\nthe dissolution of a partnership; or a partner’s retirement from a partnership, resulting in dissolution.\nPractitioners should check the legislation applicable to the relevant state or territory, to ensure that notice requirements (if any) are complied with. It may be useful to consult the state or territory website which deals with the costs and requirements of the notice.\nThis document has been authored for\nLexisNexis by Michael Heraghty, Partner, TressCox Lawyers, Rosemarie Ryan, Barrister and Jacqui L Walker, Principal Lawyer, J L Walker Law.\nThis document is prepared with the assistance of Specialist Editor\nStephen Newman, Executive Counsel, Ponte Earle..", "pred_label": "__label__POS", "pred_score_pos": 0.9356757998466492}
{"content": "N95 Respirators/Masks\nQuestion: How can you tell if a respirator is really an N95?\nAnswer: It must be approved by a government agency called NIOSH.\nThe NIOSH approval number and approval label are key to identifying NIOSH-approved respirators. The NIOSH approval label can be found on or within the packaging of the respirator or sometimes on the respirator itself. The required labeling of NIOSH-Approved N95 filtering facepiece respirators includes the NIOSH name, the approval number, filter designations, lot number, and model number to be printed on the respirator. You can verify that your respirator approvals are valid by checking the NIOSH Certified Equipment List CEL) by visiting https://www.cdc.gov/niosh/npptl/topics/respirators/cel/default.html.", "pred_label": "__label__POS", "pred_score_pos": 0.9324226975440979}
{"content": "Date of Award\n2017\nDegree Type\nDissertation\nDegree Name\nDoctor of Philosophy (PhD)\nGraduate Group\nEnglish\nFirst Advisor\nRita Copeland\nSecond Advisor\nEmily Steiner\nAbstract\nThis dissertation offers the first systematic study of the relationship between historiographical theory and literary form. I show how historians embody their conceptions of historical progress in the literary forms of their work. Beginning in the twelfth century, historians embrace a theory of historical continuity, which I call continuous history, in which continuity is seen as simultaneously continuous and discontinuous. Descriptions of catastrophic events such as conquests may rupture the smooth progression of history, but they are ultimately incorporated into the overarching narrative of the text. The resulting text typically registers this discontinuity through formal variation, which similarly challenges but does not destroy the narrative cohesion of the text. This dissertation shows how Middle English verse chroniclers utilize this theory and practice of continuous history in their own vernacular works, up to the mid-fourteenth century. It then traces how English historians from the mid-fourteenth century onwards, driven by changes in dynastic politics and intellectual culture, begin to reject continuous history in favor of new approaches such as universal history, de casibus history, and genealogical history. In contrast, however, late medieval Welsh historians persist in their use of continuous history as their primary historiographical paradigm. As a result, the mid-fourteenth and early fifteenth centuries witness the first divide of the shared British historiographical tradition into distinct English and Welsh traditions. Finally, this dissertation argues that medieval writers conceptualize the compilation of historiographical manuscripts and the writing of historiographical narrative in similar terms. For this reason, the late medieval efflorescence of genealogical rolls can be interpreted as part of a broader trend towards genealogical history in the later Middle Ages.\nRecommended Citation\nBurek, Jacqueline Marie, \"Mending A Broken Chain: Continuous History And Literary Form In England And Wales, 1125-1450\" (2017).\nPublicly Accessible Penn Dissertations. 2201. https://repository.upenn.edu/edissertations/2201", "pred_label": "__label__POS", "pred_score_pos": 0.8874470591545105}
{"content": "In a study forthcoming in Psychological Science, a journal of the Association for Psychological Science, psychological scientist Pascale Engel de Abreu of the University of Luxembourg and colleagues examine the effects of speaking two languages on the executive functioning of low-income children.\nWhile experts have noted that learning an instrument can have altruistic and positive cognitive affects on children, and while previous research has shown that being bilingual enhances executive functioning in middle-class children, researchers are curious as to how it affects lower income populations.\nSpecifically, being bilingual has a positive influence on the ability to direct and focus attention, and experts hypothesize that in children living in low-income households, learning a second language can have the added effect of encoding and structuring knowledge in memory.", "pred_label": "__label__POS", "pred_score_pos": 0.5989352464675903}
{"content": "Ship recycling activity, like any other industry, is dependent on supply and demand. Generally, ships reach their ‘end-of-life’ when their second-hand sale value for further trading drops below their recycling value.\nThis may happen due to the ship’s condition deteriorating with increasing age which may necessitate uneconomical repairs, to the demand for ships being lower than the available supply or to specific regulatory requirements.\nThe Club notes that similar to other sectors, COVID-19 impacted ship recycling operations, as according to the quarterly updates received from the NGO Shipbreaking Platform, 166 ships were demolished in the first quarter of 2020, which reduced to 98 ships in the second quarter as several recycling yards were closed due to the Covid-19 pandemic. As the restrictions are being gradually eased, operations at the demolition yards are steadily resuming.\nIn light of the pandemic and the challenges the sector delt with, BIMCO and other shipping organisations sent a joint industry letter to the European Commission (EC) requesting a time-limited implementation or grace period to enable shipping companies to make up for lost time caused by Covid-19 restrictions and interruptions.\nYet, BIMCO adds that if the 31 December 2020 deadline cannot be met, the development of IHMs on the oldest ships first. Old ships are in general more likely to be recycled and such a risk-based planning will demonstrate how shipowners are working proactively in accordance with the spirit of the EU-SRR.\nOn the demand side, the price of steel and the cost of ship-breaking are the most prominent factors. The cost of ship-breaking varies from country to country, depending on labour costs and the types of regulations on workplace safety and the environmental impact that have been implemented in that specific country.\nExplore more by clicking herebelow", "pred_label": "__label__POS", "pred_score_pos": 0.5401724576950073}
{"content": "Death, Disease and Disability – The 3D’s of Term Insurance\nEverybody might have different fears in their lives. While most of you might fear to lose your loved ones, the rest of you might be scared to lose your jobs. The primary reason for these fears can be the unpredictability of life. According to a report, it has been observed that 84% of the Indian population believes their lives are uncertain. While you might not be unable to control the uncertainties, you can protect yourselves from any announced contingency like a medical emergency, critical illness, permanent or temporary disability, and so forth.\nDue to the increasing awareness of insurance, you might opt for financial coverage to secure yourselves from emergencies. Although there are numerous insurance plans in the market, you should buy term insurance to receive financial support. Let’s first begin by understanding\nwhat is term insurance plan in detail:\nTerm insurance plans are pure protection plans with the primary objective of financial safety. In your absence, a term insurance plan offers a pay-out called the death benefit. Your family can continue to maintain their standard of living when you won’t be around to provide for them. In addition to this, the members of your family can take the decision to receive it either every month or as a whole in a lump-sum amount.\nUnder\nterm insurance plans, you can receive protection during three different scenarios, which are mentioned below. Therefore, let’s take a look to understand the three different circumstances under which term insurance plans offer financial protection: Death\nThe loss of a loved one can seem unimaginable. For instance, if you are the breadwinner of your family, your family members might not only suffer emotionally but also financially in your absence. However, you can control the financial aspect of your loss by buying term insurance. When you are unable to look after your family’s financial needs, a term plan offers a death pay-out to safeguard them in the long run.\nA term insurance plan offers high coverage at a low rate. Therefore, consider your family’s financial needs before buying term insurance. When you prioritize their financial goals, you might be able to ensure adequate financial support over a long time.\nDisease\nDue to your dynamic lifestyles and rigorous working cultures, you might be prone to critical diseases like heart attack, stroke, and so forth. Treating such severe health conditions can create a hole in your pocket due to the rising hospital costs. Due to the expensive hospital bills, you might tend to ignore your health. Delaying or ignoring the severity of any disease might have life-threatening effects on your health.\nA term insurance plan offers a life coverage along with additional riders that cover critical diseases. Therefore, you should purchase a term plan at a young age with extra riders since it might be relatively cheaper. When you\nbuy term insurance with a critical illness cover, you can receive financial aid for your severe medical condition. Disability\nSince term insurance is a protection plan, many of you might only purchase it to offer financial support to your family after your demise. However, a term plan can also help you when you are unable to provide financial protection after sustaining an injury, which might lead to permanent or temporary disability.\nDuring a permanent or temporary disability, you should purchase a physical disability cover from your insurer. When you purchase a physical disability cover, your insurer can give your sum assured amount to compensate for the loss of your income.\nTo sum up, it can be imperative to assess the risks of these 3Ds mentioned above while purchasing a term insurance policy. As a policyholder, you should use the additional riders and term insurance benefits to enhance your policy. A 3D shield under a term plan can protect you financially from the eventualities of life.", "pred_label": "__label__POS", "pred_score_pos": 0.9986767172813416}
{"content": "One of the many things that has always amazed me about Gurumayi is the way she is able to see the full potential in each one of us. When Gurumayi speaks to you, she does not speak to your fear, your insecurity, or your doubt. She speaks to your strength, your purity, and your divinity. She reaches past all of the mental and emotional barriers and touches the power and greatness within you. Gurumayi’s patience and understanding seem to have no limits.\nThis has always been my experience of Gurumayi, ever since I was a very young child. Whenever I forget my own ability or self-worth, she finds some beautifully innovative way to remind me of who I am.\nA twenty-four-year-old Siddha Yogi from New York, USA\nDuring my winter break from college last year, I offered\nseva in Shree Muktananda Ashram. Every morning, I woke up early to recite Shri Guru Gita. I treasured this practice of svadhyaya as a way of strengthening my connection to Gurumayi in my own heart.\nOne morning after reciting\nShri Guru Gita, I felt drawn to meditate on the Guru’s love. I sat for meditation, closed my eyes, and focused my gaze inside. I saw a fire blazing at the center of my being. Intuitively, I understood that the fire image was a visual representation of Gurumayi’s love—dynamic, vibrant, and full of shakti.\nI watched as the fire produced millions of golden, scintillating sparks that spread throughout my being. These sparks of divine love, of Gurumayi’s love, dissolved all tension and feelings of smallness. I felt empowered to let go of all limiting thought patterns. I felt courage and enthusiasm fill my heart.\nInspired by this experience of Gurumayi’s love, I have sought to cultivate inner strength and lightheartedness. During my regular practice of meditation, I encourage my mind to become serene—by focusing on my breath and repeating the mantra—which allows me to return my awareness to the love and joy present in my own heart.\nA nineteen-year-old Siddha Yogi from Connecticut, USA\nEver since I was a young child, I have loved watching Gurumayi enter the\nsatsang hall. Before Gurumayi takes her seat, she always acknowledges and honors her Guru. This moment is so sacred.\nA twenty-five-year-old Siddha Yogi from Sydney, Australia\nI have learned over the years that, though I have never met Gurumayi in person, I can have her\ndarshan at any time. All I need to do is pause with the intention of connecting with her. Even if I am working in my office, one brief pause can connect me to Gurumayi. Even if I am driving, a few deep breaths can give me a glimpse of Gurumayi. Even if I am eating, repetition of the mantra can reveal Gurumayi’s presence in my heart.\nThese experiences give me a single teaching: Gurumayi is always in my heart. She always listens to me, speaks to me, meditates with me. And in the moments when I long to have Gurumayi’s\ndarshan, and I put forth the effort to connect, I do perceive her presence. Because of this, I feel that Gurumayi is always very close.\nThank you, Gurumayi, for your presence in my heart. Thank you for all your blessings, which you shower on my family and me.\nA twenty-five-year-old Siddha Yogi from Pune, India\nAfter listening to Gurumayi’s Message for 2015, I was inspired to meditate. I was eager to experience the joy and bliss that comes with meditation.\nI began to meditate most nights before I went to sleep, and after doing this for a while, I realized how special it is to have the Siddha Yoga practices in my life. In a society where many of us are searching, are looking for something more, I feel lucky to have Gurumayi’s teachings, to show me a path toward my own Self.\nA seventeen-year-old Siddha Yogi from Brisbane, Australia\nI received Gurumayi’s\ndarshan for the first time when I was six weeks old. During that darshan, Gurumayi held me in her arms while my parents received her blessings. Over the years, I have come to understand and experience that when Gurumayi took me in her arms that day, she cradled me in her grace and never let me go.\nA twenty-three-year-old Siddha Yogi from California, USA\nOne day as I sat for meditation, I reflected on a photograph I have of Gurumayi seated in meditation. In the photo, Gurumayi looks perfectly serene.\nI closed my eyes, and I could still see Gurumayi. As my mind grew quiet, I had the realization that Gurumayi was not separate from my own consciousness. It was not just a familiarity with Gurumayi I was recognizing; it was the clear understanding that deep inside, we are the same. I had the experience of the great Siddha Yoga teaching that the Guru and the inner Self are one.\nWhen I came out of meditation, I was crying with gratitude. What a gift Gurumayi had given me, to be able to close my eyes, go inside, and know my own inner value.\nA twenty-two-year-old Siddha Yogi from Massachusetts, USA", "pred_label": "__label__POS", "pred_score_pos": 0.8985012173652649}
{"content": "For centuries, Myrrh essential oil has been beloved for its numerous wellness and beauty benefits. Find out where it originates from, usage tips, and so much more with these nine fun facts.\nWe all have a friend who doesn’t lose their cool, no matter the situation; consider Vetiver that friend of your oil collection. Warm, welcoming, and woody, Vetiver’s aroma helps bring calm and relaxation to work and play.\nWhile people in ancient times quickly recognized the value of using* pure botanicals, methods for extracting the essences of those botanicals have evolved slowly over time. Let’s explore the development of these processes, from the most basic to today’s advanced methods.", "pred_label": "__label__POS", "pred_score_pos": 0.6262964010238647}
{"content": "India’s healthcare sector is expanding at a CAGR of 16%-17% and is expected to reach US$ 372 billion by 2022. Additionally, the market for medical equipment in this country is also on the rise. It is expected to reach US$ 11 billion by the end of the same year.\nData like these portray the enormity of the healthcare sector in this country. The same also suggests that it is the right time to invest in this sector.\nFinancial institutions across the country are offering doctor loans to medical professionals to encourage them to invest and improve the healthcare system even further.\nconsist of both secured (loan against property, home loan) and unsecured (business loans, personal loans) advances. Doctor loans\nMedical practitioners can avail such credits to fulfill their various needs such as establishing a clinic, modernizing their existing one or purchase equipment, etc.\nUsability of doctor Loans Facility 1. Starting a new clinic\nApart from the extensive public medical system of India, the size of private healthcare in this country is also significant. Such private clinics have an essential role in India’s healthcare system. More often than not, these are the ones that provide critical treatment to a majority of patients.\nHence, doctors also become keen on opening their practice due to the wide possibilities it offers. However, it requires a substantial initial investment to start a medical practice.\nThus, financial institutions in the country are offering credit at affordable terms to encourage doctors to open clinics and provide medical support to their local communities.\nOne such example of credit is a loan against property offered under the umbrella of doctor loans. Individuals can borrow up to Rs.2 crore at a competitive interest rate to start their medical practice. Furthermore, it has a flexible tenor of up to 18 years which makes the repayment easy.\n2. Upgrading equipment\nModern and new age equipment are required to provide better services to the patients. However, such modern technology does not come cheap.\nTo arrange this corpus, doctors can opt for either a business loan or a loan against property. With the former, they can avail a considerable amount of up to Rs.37 lakh and upgrade their medical equipment today.\n3. Renovate the existing practices with Doctor Loan\nTo comply with the rapid growth of the healthcare sector, existing clinics need to reinvigorate their position to be able to attract more patients. A quick renovation of it can help in this cause.\nHealthcare professional can avail business loans or personal loans available as a part of doctor loans for this matter. The credit amount can go up to Rs.37 lakh, and the interest rate is attractive.\nMoreover, these have a tenor of up to 96 months, making the repayment affordable. Additionally, the quick disbursal nature of this financial product makes it easy to avail.\n4. Expanding existing practices\nMedical practitioners can also invest and expand their existing clinics or hospitals. They can apply for a secured loan to purchase or lease a property to expand their services.\nThey can avail up to Rs.2 crore for this purpose at a competitive interest rate. The tenor of this loan is up to 18 years, making it more affordable to repay. Additionally, lenders offer top-up loans for fulfilling further requirements.\nProminent NBFCs like Bajaj Finserv bring such loans to aid medical practitioners in investing in this sector and provide better healthcare services.\nThe company is offering various Bajaj physician loans at attractive interest rate, flexible tenor, part pre-payment facility and quick disbursal.\nFurthermore, the NBFC also brings pre-approved offers to make the loan application process hassle-free and less time-consuming. These offers are available on a host of financial products like business loans, personal loans, etc. Loan applicants can check their pre-approved offers by submitting their essential contact details.\nThe healthcare sector in India is showing great promise and is expected to grow even further. With financial institutions offering affordable doctor loans to help healthcare professionals to invest in this sector, it is the right time to invest in this sector and serve their country.", "pred_label": "__label__POS", "pred_score_pos": 0.7968848943710327}
{"content": "A mouthguard helps absorb the shock experienced by a blow to the face, which might otherwise result in an injury to the mouth or jaw. A heavy collision can result in chipped or broken teeth, internal damage to a tooth, tooth loss, injuries to the soft tissue of the mouth, and, in severe cases, concussion or a broken jaw. Injuries like these can lead to long and potentially expensive treatment to restore teeth and the mouth back to normal function and appearance.\nTypes of Mouthguards:", "pred_label": "__label__POS", "pred_score_pos": 0.838060200214386}
{"content": "LRN’s culture is a fundamental part of every solution, service, and product we build. As a Mission with a Business, we are guided by who we are and who we want to be as much as what we want to achieve.\nAs a mission with a business, we are guided by who we are and who we want to be as much as what we want to achieve. LRN Leadership Framework VALUES AND LEADERSHIP\nWe believe enduring success is achieved through inspired, ethical leadership—regardless of tenure, job function, or position in an organizational chart. Over time, ethical leadership shapes a culture that governs itself according to shared corporate values.\nThe LRN Leadership Framework defines, galvanizes, and unifies our culture, inspiring and informing our conduct whether we’re collaborating with colleagues or our Partners. The LRN Leadership Framework is an interconnected, mutually reinforcing set of principles that reflects the multi-faceted quality of ethical leadership. It is a living constitution that brings our core values to life, guiding our everyday business decisions and actions, and allowing us to consider our conduct in a broader, more-reflective context that which supports evolution and journey as an organization.\nCORE VALUES\nLRN’s core values are truth, humility, passion, and integrity. These are the essential elements that comprise our corporate DNA. They are the touchstones of who we wish to be, and the first points of reference when making business decisions or behavioral choices. In various combinations and applications, they are the basis for our Leadership Framework and the type of leader it describes.\nHUMILITY\nWe believe that achieving sustained excellence is predicated on humility, which enables us to collaborate, self-evaluate and reinvent. We believe that humility leads to strength, not weakness. No matter what standards we achieve or how much pride we take in what we do, arrogance is not for us.\nINTEGRITY\nWe believe that acting with integrity, in accordance with ethical principles and shared corporate values, is the ultimate driver of productivity and performance. For us, integrity is the steady application of our Code of Conduct. It is the ongoing, consistent demonstration of our values throughout our work.\nPASSION\nWe believe that success arises out of the passionate pursuit of a meaningful and significant goal. We are intensely committed to our mission here, and we pursue that mission with unwavering energy and conviction.\nTRUTH\nWe believe truth is the foundation for trust, and trust propels productivity and progress. Nothing is worth pursuing if its pursuit is not truthful and authentic.", "pred_label": "__label__POS", "pred_score_pos": 0.9712576270103455}
{"content": "DC Inadequate Testing Lawyer\nPatients trust healthcare providers to address their injuries and illnesses through proper examination and testing. If your doctor does not order the correct tests, your medical condition may not be diagnosed in time, and you may face additional harm as a result.\nIf a physician or other healthcare professional fails to order or interpret tests pertinent to your condition and you are injured because of their errors, an medical malpractice attorney at our firm could help you take advantage of your legal rights. Let a DC inadequate testing lawyer help you hold negligent medical professional accountable.\nInadequate Testing Can Constitute Medical Malpractice\nWhen physicians treat patients, they are expected to adhere to the accepted standards of medical care established by other healthcare professionals with similar experience. For instance, every doctor is responsible for ordering blood tests to monitor a patient’s glucose levels, cholesterol, and liver function, as well as X-rays for those with suspected broken bones.\nIf a physician fails to order blood tests for a patient with diabetes, for example, their condition will go unchecked, leading to organ damage and possible amputation. Failing to order a test in this case is a form of medical malpractice, which is based on the legal theory of negligence. A local attorney could review the details of a patient’s case and work to hold a negligent healthcare provider accountable for their injuries.\nTypes of Testing Critical to Patient Care\nMedical tests can offer conclusive proof of what is going on inside a person’s body and detect diseases and conditions that can quickly turn deadly, such as cancer, diabetes, stroke, and tumors. Some essential medical tests include:\nBlood tests that are crucial in detecting diabetes, high cholesterol, thyroid, and liver conditions Computed tomography (CT or CAT) scans that use computer-assisted X-rays to produce internal pictures of organs, bones, and tissues Magnetic resonance imaging (MRI) that use a computer, a powerful magnetic field, and radiofrequency pulses to create detailed photos of inside the body Electrocardiogram (ECG), which measures a patient’s heartbeat Ultrasound scans that monitor a fetus while the mother is pregnant\nIf a healthcare provider fails to order or interpret any of these critical tests, one of our attorneys could determine whether they should be liable for malpractice.\nFiling a Lawsuit\nThe Code of the District of Columbia §16–2802 specifies that all defendants to a medical malpractice lawsuit must be notified of the patient’s intent to sure at least 90 days before their claim is filed.\nAll parties are also required to attend non-binding mediation before engaging in civil litigation. Notice and mediation are the District’s way of encouraging settlement rather than bogging the judicial system down with lengthy and expensive litigation. An attorney in our area could discuss this complex legal process with anyone thinking about filing a lawsuit for inadequate medical testing.\nContributory Negligence\nUnder the doctrine of pure contributory negligence, plaintiffs who are found even one percent responsible for their injuries will be barred from recovering any damages whatsoever. For instance, if a physician orders a test critical to a patient’s treatment, but the patient cancels the testing appointment and fails to reschedule it, both parties might be found liable if the doctor fails to follow up and the patient never gets the test until it is too late.\nA DC Inadequate Testing Lawyer is Standing By\nMedical tests are a critical component of a patient’s treatment, as they determine the cause of many illnesses and ailments. It is your right as a patient to receive adequate testing from your physician or healthcare provider. If you explained to your doctor how you feel, and the applicable tests were not ordered while your condition worsened, you should contact a DC inadequate testing lawyer to discuss your situation. Schedule a consultation today.", "pred_label": "__label__POS", "pred_score_pos": 0.6867254972457886}
{"content": "Previous studies have shown the feasibility of using diffusion tensor imaging (DTI) as a noninvasive imaging modality to evaluate neurodegeneration in humans and animals. The axial and radial diffusivities derived from DTI were demonstrated to be sensitive markers for axonal and myelin damage, respectively. This study used DTI to evaluate optic nerve degeneration in wild-type and slow Wallerian degeneration (Wld(S)) mutant mice. Longitudinal DTI was performed on optic nerves following high intraocular pressure-induced transient retinal ischemia. The axial diffusivity of wild-type nerves decreased 30% (P<0.05) at 3 days and 40% (P<0.05) at 5-30 days after transient elevation of intraocular pressure. In contrast, the axial diffusivity of Wld(S) nerves did not change at 3 days; decreased by 20% (P<0.05) at 5 days, and continued to decrease by 30% (P<0.05) at 15 days and 40% (P<0.05) at 30 days after transient intraocular pressure elevation, suggesting delayed axonal damage in Wld(S) mice. Radial diffusivity increased 200% (P<0.05) at 15-30 days in the wild-type mice and 100% (P<0.05) at 30 days in the Wld(S) mice after transient intraocular pressure elevation, suggesting delayed myelin damage in Wld(S) mice. DTI detected damage was confirmed with immunohistochemistry using phosphorylated neurofilament and myelin basic protein for assessing axonal and myelin integrity, respectively. These findings support the use of DTI not only to evaluate the progression of neurodegeneration but also to noninvasively demonstrate Wld(S) mutation to delay the Wallerian degeneration.\nCopyright © 2011 IBRO. Published by Elsevier Ltd. All rights reserved.", "pred_label": "__label__POS", "pred_score_pos": 0.6552492380142212}
{"content": "The report highlights that the European Green Deal and the European Strategy for data will necessitate reliable, accurate and centralised data for its initiatives.\nThe third edition of the report also includes new elements, which have an impact on the Blue Economy, including challenges like climate change, new sectors such as Submarine cables), enablers such as Maritime Spatial Planning, new areas of analysis such as Ecosystem Services or potential solutions like Multipurpose platforms.\nMoreover, the report consists of:\nMarine-based activities: include the activities undertaken in the ocean, sea and coastal areas, such as Marine living resources (capture fisheries and aquaculture), Marine minerals, Marine renewable energy, Desalination, Maritime transport and Coastal tourism. Marine-related activities: activities which use products and/ or produce products and services from the ocean or marinebased activities like seafood processing, biotechnology, Shipbuilding and repair, Port activities, technology and equipment, digital services, and other.\nHowever, the ocean has an economic value which is hard to quantify in terms of provision of resources, habitat for marine life, carbon sequestration, coastal protection, waste recycling and\nstoring, and processes that influence climate change and biodiversity. To the extent possible, the Report covers most of these issues too.\nFollowing the implementation of the European Green deal, the report analyzes the impact of human factor on the marine environment, and especially on the ocean.\nThe human impact includes the greenhouse gases (GHGs) which are the main contributor to global warming and climate change. Climate change is expected to result in more frequently heat waves, forest fires and droughts in Southern and Central Europe. While, Northern Europe will become significantly wetter, and winter floods could become common.\nIn the meantime, the report outlines some challenging issues, such as the general economic and political context, providing a background to the Blue Economy, including the sources of financing available for the Blue Economy projects.\nTo learn more about the report click herebelow", "pred_label": "__label__POS", "pred_score_pos": 0.8672177195549011}
{"content": "Over the past 25 years, Lynne has coached individuals, families and their foundations to resolve the complex dynamics surrounding philanthropic issues of wealth and personal and global responsibility.\nSpecifically designed for individuals and families of wealth, Lynne offers philanthropic consulting that facilitates clients in finding appreciation, joy and meaning in their relationships beyond financial conflict. The types of people who have benefited from Lynne’s Philanthropic Consulting include:\nIndividuals who have financial resources that they want to dedicate to philanthropy but are not sure of the best path forward. Individuals already engaged in philanthropic works who want to gain more clarity on the difference they can make with their contribution. Family members who want to engage their children, brothers, sisters and spouses in working on the dynamics that go along with inherited wealth. Individuals or families of great wealth who desire to align behind a powerful vision and set up an organization, foundation or institution that is designed around a powerful giving strategy. Individuals or families of great wealth who feel overwhelmed by constantly being asked for money from various causes and instead want to consciously design their philanthropic giving.\nThe first step in the process involves Lynne assisting her clients in determining their philanthropic vision by formulating a clear sense of their personal values. Next, Lynne facilitates her clients in organizing their values to effectively develop and enact their vision. Lastly, with a focus on creating life affirmation and sincere joy through a sense of responsible financial stewardship, Lynne empowers her clients to translate their philanthropic philosophy and passion into all areas of their lives, including nurturing healthy relationships with those around them.\nAlign your wealth with your vision.\nCLICK HERE to fill out the Soul of Money Consulting Intake Form and our team will get back to you as quickly as possible.\nThis experience has opened and expanded my time and energy by helping me clear situations that were heavy and draining while inviting people, work, and circumstances that align with my greatest passions.\nHilaryPhilanthropic Consulting Client", "pred_label": "__label__POS", "pred_score_pos": 0.9068521857261658}
{"content": "November 9, 2020\nMoney Launderers Will Easily Dodge Detection under New BC Public Land Registry British Columbia’s new public land registry has significant flaws that greatly undermine its ability to help investigators detect money laundering in BC real estate. In “BC’s Public Registry to Combat Money Laundering: Broken on Arrival” Kevin Comeau lays out the changes that should be made to the registry to give it the teeth it needs to be a serious deterrent to criminals, including improving identity verification and searchability, imposing prison sentences on those who provide false information, and scrapping the $5 user fee. If the key recommendations in the report are adopted, the BC public registry would become a powerful tool to combat money laundering in BC real estate. It would help reduce upward pressure on housing costs, generate significant government revenue, undermine the principal foundation upon which international money-laundering systems are built, and provide added safeguards against international money laundering, including from authoritarian regimes.", "pred_label": "__label__POS", "pred_score_pos": 0.558465838432312}
{"content": "About Services Membership Events BayGrow NMB Sectors Trending\n2020-08-19\nNelson Mandela Bay is facing Day Zero as the City’s combined dams have plummeted to alarmingly low levels.\nDay Zero looming as Metro dams plummet to alarmingly low levels\nNelson Mandela Bay is facing Day Zero as the City’s combined dams have plummeted to alarmingly low levels.\nThe situation has become so severe with projections that parts of the metro could be without water by March 2021 if the current consumption trend continues unabated. As such, the Nelson Mandela Bay Business Chamber has reached out to the Municipality to ascertain where it can assist with addressing some of its challenges. It has also begun making calls to its member companies to urgently reduce their daily consumption by 20%.\nThe city’s biggest dam, the Kouga Dam, currently has a supply of 6.80% of its capacity, the Churchill Dam at 49.48%, the Loerie Dam at 34.27%, the Groendal Dam at 25.59% and the Impofu Dam at 16.71%. They have a combined supply which is 16.93% of their capacity. While almost two-thirds of the city’s water supply is supplied from the Gariep Dam, one-third comes from these Western dams.\nCurrently, the metro is consuming 290 megalitres (ML) of water per day while targeted consumption should be 250ML. We are still a long way from the targeted 250ML/day\nFor a city whose economy is anchored by industries that rely on the availability of water for their operations, the current state of the Bay’s water supply places the city in a precarious position. If companies cannot operate in full capacity, this would inevitably lead to job losses and negatively impact the already overburdened local economy.\nThe situation demands full commitment from both residents and the business community to ensure we all play our part in securing our water supply. As an entity that represents businesses in the Metro, we call on our members, as part of their corporate social responsibility, to consider offering their expertise to the Municipality to assist with some of its challenges. With water leaks also being a problem in some schools in the metro, a company could adopt the school and help with fixing their leaks.\nMetro households must now be vigilant and monitor their water consumption to ensure they keep to the restricted amount of 50 litres per day. Businesses should continue to investigate innovative water-saving techniques and infuse them in their daily operations. We would like to commend companies such as Volkswagen South Africa, Isuzu Motors and many others, for being at the forefront of curbing water consumption through innovation.\nWhile the Bay this week received good rains, far more would be required to make a significant impact to our already severely depleted water resources. As such, we need to intensify our water-saving efforts to ensure the city does not reach Day Zero.\nNomkhita Mona\nCEO, NMBBC", "pred_label": "__label__POS", "pred_score_pos": 0.7357348203659058}
{"content": "What is Substitution?\nSubstitution refers to the act of an individual deliberately providing a counterfeit version of a urine specimen via a third-party source or through a synthetic product available on the market that mimics the biochemical compounds of genuine urine. In Canada, many industrial labor occupations are notorious for employees resorting to substituting their urine specimen for an otherwise legitimate sampling as a means to gain drug clearance.\nInitially, urine drug testing serves as a preventative measure in appointing individuals to safety-sensitive positions where any level of impairment could pose hazardous risks inside the workplace. However, many applicants and employees anticipating urine drug screens often rely on substitution methods as a loophole to maneuver around a positive test result that can draw assumptions of a suspected drug problem. Urinalysis tends to advance one-sided inferences that show the existence of drug metabolites in the system, yet fails to establish if addiction or drug impairment at the time of testing are questionable factors.\nMoreover, companies often enlist certified laboratories that operate under the U.S. Department of Transportation (DOT) apparatus, which illustrates the guidelines consistent with substitution issues that may require a battery of testing. Gas chromatography-mass spectrometry (GC-MS), for example, is a sophisticated application that targets and isolates drug metabolites, linking the enzymatic properties of drug classes and their derivative compounds against cutoff thresholds values. Lab technicians note crucial factors such as coloration, odors, and temperature deviations in effectively weighing the validity of urine specimens based on their acidic content, which can play into the equation of substitution cases.\nSynthetic urine products remain popular, especially given their ability to neutralize creatinine levels, a catalytic byproduct of muscular synthesis. As Canada does not outright prohibit substitution practices, employers must contend with lax measures that exempt possible repeat drug users in the way of forfeiting a drug-free workplace environment.", "pred_label": "__label__POS", "pred_score_pos": 0.922863245010376}
{"content": "The next census, set to begin on April 1, 2020, will bring a renewed focus on the populations that have historically been hard to count. These include the unemployed, those living below the poverty line, and people with limited English proficiency. People without internet access are also included since the 2020 census will strongly encourage online submission of census forms. Taken as a whole, Arkansas counties have an average poverty\nLast week the Census Bureau released their 2020 Census Barriers, Attitudes, and Motivators Study Survey. This survey was intended to identify and understand the major challenges to a full response to the 2020 Census since less than seven in ten households who participated in the study indicated they were very likely or extremely likely to fill out the Census form. According to the report, the five concerns that might prevent", "pred_label": "__label__POS", "pred_score_pos": 0.9892964363098145}
{"content": "Commonwealth of Virginia Office of Governor Ralph S. Northam FOR IMMEDIATE RELEASE ·\nMarch 17, 2020\nOffice of the Governor Governor Northam Announces NewMeasures to Combat COVID-19 and Support Impacted Virginians ~ Directs adherence to 10-person gathering ban, quarantine for high-risk individuals, worker and employer support ~ RICHMOND—Governor Ralph Northam today announced additional steps to help Virginians impacted by novel coronavirus, or COVID-19, stop the spread of the virus in the Commonwealth, and protect public health. “Everyone must play a role to help flatten the curve and mitigate the spread of this virus, and that starts with social distancing,” said Governor Northam. “We know this will be a hardship for many businesses, and we are assisting workers affected by closures. Public health relies on every individual using common sense and making responsible decisions. We can and will get through this difficult time. But we must work together to do so.”\nVideo of today’s media briefing is available here.\nFurther Reducing Public Gatherings\nGovernor Northam told Virginians to avoid non-essential gatherings of more than 10 people, per federal guidelines. This does not include normal operations at essential services such as manufacturers, distribution centers, airports, bus and train stations, medical facilities, grocery stores, or pharmacies.\nProtecting High-Risk Virginians\nThose with chronic health conditions or aged 65 or older should self-quarantine. Public health experts advise that individuals with underlying medical conditions and those aged 65 or older are at increased risk of severe illness from COVID-19. Governor Northam encouraged neighbors and friends to stay in touch and regularly check in with high-risk individuals.\nIncreasing Social Distancing All restaurants, fitness centers, and theaters are mandated to significantly reduce their capacity to 10 patrons, or close. Restaurants are encouraged to continue carry-out and takeaway options. Support for Affected Workers\nGovernor Northam announced the following actions to protect working Virginians impacted by the COVID-19 outbreak:\nNo waiting for unemployment benefits.\nGovernor Northam has directed the Commissioner of the Virginia Employment Commission to waive the one-week waiting period to ensure workers can receive benefits as soon as possible.\nEnhanced eligibility for unemployment.\nWorkers may be eligible to receive unemployment benefits if an employer needs to temporarily slow or cease operations due to COVID-19. If a worker has been issued a notice to self-quarantine by a medical or public health official and is not receiving paid sick or medical leave from their employer, they may be eligible to receive unemployment benefits. In addition, a worker may be eligible for unemployment benefits if they must stay home to care for an ill family member and are not receiving paid family medical leave from their employer.\nFewer restrictions.\nFor individuals receiving unemployment insurance, Governor Northam is directing the Virginia Employment Commission to give affected workers special consideration on deadlines, mandatory re-employment appointments, and work search requirements. The Office of the Governor is providing a Frequently Asked Questions guide for workers that have been temporarily laid off or discharged during this public health crisis.\nSupport for Impacted Employers\nRegional workforce teams will be activated to support employers that slow or cease operations. Employers who do slow or cease operations will not be financially penalized for an increase in workers requesting unemployment benefits. The Governor is authorizing rapid response funding, through the Workforce Innovation and Opportunity Act, for employers eligible to remain open during this emergency. Funds may be used to clean facilities and support emergency needs. Governor Northam is directing all employers to follow U.S. Department of Labor guidance on workplace safety.\nDepartment of Motor Vehicle Office Closures\nVirginia’s 75 DMV offices, as well as mobile units, will close to the public. Online services will remain available, and anyone needing to renew a license or vehicle registration is encouraged to do so online.For those who cannot renew online, or whose license or registration expires before May 15, DMV will grant a 60-day extension.\nCourts Governor Northam requested and the Supreme Court of Virginia granted a judicial emergency in response to COVID-19. From Monday, March 16 through Monday, April 6, non-essential, non-emergency court proceedings in all district and circuit courts are suspended absent a specific exemption. This includes a prohibition on new eviction cases for tenants who are unable to pay rent as a result of COVID-19. All non-exempted court deadlines are tolled and extended for a period of 21 days. Utilities\nThe State Corporation Commission (SCC) issued an order directing utilities it regulates, such as electric, natural gas, and water companies in Virginia, to suspend service disconnections for 60 days to provide immediate relief for any customer, residential and business, who may be financially impacted by the COVID-19 outbreak. For a comprehensive list of actions Governor Northam has announced to combat COVID-19 in Virginia, visit virginia.gov/coronavirus. Full Release ###\n—\n—\n************************************************", "pred_label": "__label__POS", "pred_score_pos": 0.5047512054443359}
{"content": "Who doesn't love burning candles? They are calming and relaxing, but non-beeswax candles can be detrimental to your health - this is because when burning, they release paraffin as a by-product.\nBeeswax is the only wax that occurs in nature, so there are no processing chemicals in these candles!\nWhen burning, beeswax candles release negative ions which clean the air by combatting dust, odours, moulds and viruses. This has the added benefit of elevating people's moods!\nBurns for 100 hours", "pred_label": "__label__POS", "pred_score_pos": 0.8775327205657959}
{"content": "Abstract : Among the new microtubule-targeted agents, the epothilone family of molecules has shown promising anticancer potential, and clinical trials are currently underway for patupilone (epothilone B) in various cancer indications. In this study, we characterized novel aspects of patupilone's cellular action that may underlie its potent cytotoxicity in human neuroblastoma cells. Patupilone induced mitochondrial membrane potential collapse, mitochondrial morphological changes, and cytochrome c release, leading to apoptosis. Within the first 2 h, patupilone increased the generation of reactive oxygen species (ROS; i.e., superoxides and hydrogen peroxide, 33+/-6 and 51+/-3% increase, respectively), specifically from mitochondria. ROS scavengers and mitochondrial DNA depletion [rho(-) cells] significantly protected cells against patupilone cytotoxicity, indicating that ROS generation is a key event in the initial phase of apoptosis. Although the Bim expression level was not modified by patupilone, this proapoptotic protein accumulated in the mitochondrial compartment (2.4-fold increase at IC70) after only a 6-h treatment. In contrast, Bax and Bcl-2 mitochondrial levels were not changed during treatment. It is noteworthy that ROS inhibition prevented Bim relocalization to mitochondria and mitochondrial membrane changes induced by patupilone. Altogether, our data reveal that patupilone-mediated ROS production by mitochondria initiates the intrinsic signaling cascade by inducing Bim accumulation in mitochondria. These results might explain the superior activity of patupilone in tumor cells compared with paclitaxel that is, until now, the clinical reference among microtubule-stabilizing agents. Furthermore, our data highlight the importance of mitochondria that simultaneously assume the role of activator and integrator of apoptotic signals triggered by patupilone.", "pred_label": "__label__POS", "pred_score_pos": 0.6703412532806396}
{"content": "Over at CSCS, Simone Ulmer writes that researchers at ETH Zurich have clarified the previously unresolved question of whether fish save energy by swimming together in schools. They achieved this by simulating the complex physics on the supercomputer ‘Piz Daint’ and combining detailed flow simulations with a reinforcement learning algorithm for the first time. “In their simulations, they have not examined every aspect involved in the efficient swimming behavior of fish. However, it is clear that the developed algorithms and physics learned can be transferred into autonomously swimming or flying robots.”", "pred_label": "__label__POS", "pred_score_pos": 0.9998540878295898}
{"content": "I don’t remember how the habit started. It wasn’t a conscious choice like taking up jogging, but it developed as all do—progressively. One act of pleasure bumps into another until it’s a daily delight. A treat. And my oh my. How can something that brings a smile one day and on the next, seem to be wrong? Another one? Isn’t that excessive? No one else is involved. After all, I’ve got this handled.\nAt times, I stay up too late browsing the internet. I’m not reading a good book or researching my family tree, just browsing random crap. YouTube videos, current news, or shopping for things I’ll never buy. If I were reading, at least it would be beneficial for my brain cells, right? So down the trail and then turn right. Stop!\nMy one-year-old cat, Dot, is a hunter. He drags his “kills.” He attacks, wrestles, and drags small rugs and blankets around the house. They are gnawed to death. Usually, they are tugged to the food bowl, him growling the entire way. I see it as some instinct he has to bring in a carcass. His version of the gazelle is a brown Mexican blanket that he yanks by its corner. Sometimes he’ll donate his prey to the other cats while they sleep.\nDot has a Q-tip habit. He begs for them, even meowing and waking me at two in the morning when the rest of the world is sleeping. He needs a fix. It is nearly an obsession. Cat games. This cat hunts ear swabs. He hides his skinny, ear swab prey under a rug, then pounces, then discovering it again.\nCreatures of nature are instinctive. Humans use instincts but also have developed habits. But we can update old practices. Thankfully we can learn. Whatever it is we want to alter, we can retrain ourselves. It feels odd at first. If it’s essential and we introduce it consistently, we can change. But Dot, the hunter, might forever be addicted to his human ear probes. I might forever be gathering them from odd places, like from my shoes.", "pred_label": "__label__POS", "pred_score_pos": 0.8232375979423523}
{"content": "This article analyzes the impact of crowdfunding on journalism. It is based on a case study about Spot.Us, a platform pioneering community-funded reporting. The study concludes that a crowdfunded journalistic process requires journalists to renegotiate their role and professional identity to succeed in the changing realm of creative work. It also concludes that reader donations build a strong connection from the reporters to the donors, which creates a new sense of responsibility to the journalists. The journalists perceive donors as investors, that cannot be let down. From the donor's perspective, donating does not create a strong relationship from donor to the journalist, or to the story to which they contributed. The primary motivation for donating is to contribute to the common good and social change. Consequently, donors’ motives are essentially more altruistic than instrumental.\nAbstrakt / Utdrag", "pred_label": "__label__POS", "pred_score_pos": 0.9960799813270569}
{"content": "Abstract\nNon-Hispanic black (NHB) women are more likely to experience an endometrial carcinoma (EC) recurrence compared to non-Hispanic white (NHW) women. The extent to which tumor characteristics, socioeconomic status (SES) and treatment contribute to this observation is not well defined. In the NRG Oncology/Gynecology Oncology Group (GOG) 210 Study we evaluated associations between race/ethnicity and EC recurrence according to tumor characteristics with adjustment for potential confounders. Our analysis included 3,199 NHW, 532 NHB and 232 Hispanic women with EC. Recurrence was documented during follow-up. We used Cox regression to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) for associations between race/ethnicity and EC recurrence in models stratified by histologic subtype (low-grade endometrioid, high-grade endometrioid, serous, mixed cell, carcinosarcoma, clear cell) or stage (I, II, III) and adjusted for age, SES, body mass index, smoking status and treatment. In histologic subtype-stratified models, higher EC recurrence was noted in NHB women with low-grade endometrioid (HR = 1.94, 95% CI = 1.21–3.10) or carcinosarcomas (HR = 1.66, 95% CI = 0.99–2.79) compared to NHWs. In stage-stratified models, higher EC recurrence was noted among NHB women with stage I (HR = 1.48, 95% CI = 1.06–2.05) and Hispanic women with stage III disease (HR = 1.81, 95% CI = 1.11–2.95). Our observations of higher EC recurrence risk among NHB and Hispanic women, as compared to NHW women, were not explained by tumor characteristics, SES, treatment or other confounders. Other factors, such as racial differences in tumor biology or other patient factors, should be explored as contributors to racial disparities in EC recurrence.\nKeywords outcomes racial disparities socioeconomic status tumor heterogeneity uterus neoplasm", "pred_label": "__label__POS", "pred_score_pos": 0.681180477142334}
{"content": "SINGAPORE — October 2, 2018 — The DyStar Group has released its 2017-2018 Sustainability Performance Report. Into its eighth edition, the report marks the progress of the global company that aspires to become the world’s most sustainable and responsible supplier of colorants, specialty chemicals, and services in the textile industry, but has also embarked on the business with food dyes and chemicals through its recent acquisition in United States.\nThe latest DyStar’s Sustainability Performance Report is the first of their reports prepared in accordance with the most trusted and widely used reporting framework – Global Reporting Initiative (GRI) Standards: Core Option.\nThe 2020 Target\n2017 marks the seventh year of DyStar’s journey towards reducing the production footprint by 20% for every ton of production by the year 2020. This goal encompasses the resources used for production including energy, water, and raw materials as well as addresses their corresponding outputs — greenhouse gas (GHG) emissions, waste and wastewater. Results across most key performance indicators were positive, with four of the six 2020 targets being successfully met or surpassed.\nIn terms of the energy consumption and GHG emission, DyStar is farther from its original desired target primarily due to the impacts from three newly acquired production sites. However, intensive efforts are underway to ensure that the company’s less efficient acquisitions are provided the essential support to align with the rest of the company. DyStar is optimistic that all six targets are achievable by 2020.\nCreating Responsible Products & Services\nAs part of DyStar’s long-term goal to imbed sustainability across the industry, they will also be focusing on expanding its sustainability services. This includes the opening of more Texanlab offices, an ISO 17025 certified, specialized testing laboratory across South Asia to provide end-to-end solutions throughout the whole supply chain.\nStepping Up on Cooperation with NGOs\nIncreasingly, DyStar is strengthening their partnerships with the Non-Governmental Organizations (NGOs). The 2017 report features an in-depth guest interview with the NGO China Water Risk, on how can suppliers like DyStar can be a role model in creating sustainable fashion.\nTo encourage and facilitate sustainable practices among its suppliers, DyStar also conducts sustainability-related supplier surveys. For instance, DyStar is cooperating with the Institute of Public & Environmental Affairs (IPE), one of the most established Chinese NGO, to expand the framework of their supplier questionnaire. In recognition of its efforts, DyStar received top ranking in the CITI transparency list for industrial chemicals from IPE, placing them well ahead of many other industry peers.\nEmbracing Diversity, Engaging Communities\nAlso, to help meet clients’ demand and demonstrate its responsibility and care in the food and beverages industry, DyStar is implementing a supplier diversity program to support businesses in the USA that are at least 51% owned by minority groups, women, veterans and people with disabilities.\nHighlighting DyStar’s commitment to the communities they operate in, the company encourages volunteerism among employees, and for the year of 2017, DyStar employees devoted a total of 205 volunteer hours towards community projects, which also served as a meaningful collective experience for employees to form closer bonds.\nWorking Together Towards Long-Term Solutions\nAs an industry frontrunner, DyStar and its leaders are committed to driving sustainability across the industry. However, significant challenges remain, and the stakeholders of this industry need to work together to derive long-term solutions. CEO of DyStar Group, Mr. Eric Hopmann emphasized, “It is imperative for the entire industry to improve collectively, not individually, and our ability to do so may determine the long-term profitability of the industry as a whole. It is my belief that effective partnerships coupled with stronger support and incentivization from leading companies within this industry could be key to creating a new – and much needed – equilibrium.”\nPosted October 3, 2018 Source: DyStar Group", "pred_label": "__label__POS", "pred_score_pos": 0.6065530776977539}
{"content": "The results of previous environmental due diligence activities indicate that the site had operated as an industrial facility since the early 1950s with on-site use and storage of hazardous materials. Soil analytical data for the site indicated the presence of hazardous compounds beneath a portion of the industrial complex at concentrations that could result in an unacceptable indoor air inhalation exposure. While not liable to remediate the contaminants, the current owner elected to take preventative measures to preclude unacceptable vapor intrusion exposures in the structure.\nInitially, Envirologic installed Vapor Pins® across the impacted structure and collected soil gas samples to evaluate the sub-slab conditions. Sample results indicated the presence of chlorinated compounds in excess of the 2013 Vapor Intrusion Screening Levels (VISLs) in soil gas across an area of approximately 8,500 square feet (SF) of the 47,500 SF structure.\nEnvirologic conducted pressure field extension testing (PFE) at several locations in the impacted area to evaluate sub-slab depressurization (SSD) as a technology to mitigate the vapor intrusion concerns. Initial test results indicated that the base course materials directly beneath the concrete slab were too tight and/or compacted for effective depressurization. Depressurization from suction pits in the base course materials would have required a considerable blower system or a typical (more economical) blower system with more than 15 suction points.\nAdditional site evaluation indicated that a lower sand layer (2\"-3' bgl) was conducive to vapor extraction, and the effects of depressurization of the sand layer extended upward through the overlying soils and base course materials, resulting in a suitable pressure field below the concrete slab.\nBased on the results from the PFE testing, Envirologic designed an SSD system that included three suction (vapor extraction) points across the impacted portion of the facility. The suction points were constructed with 0.20 slot well screens positioned to intersect the underlying sand layer. Three-inch-diameter suction piping was extended from each vapor extraction point through a sub-surface trench to a piping manifold along the outer wall of the structure, and then to an OBAR SOE-76 Compact Radial Blower mounted on the exterior wall. Performance monitoring results from vapor pin and test point locations in the impacted area indicated that the system had induced a sub-slab vacuum (> -0.02\" water column - WC) across the impacted area.\nFollowing the rescission of the 2013 VISLs and introduction of Volatilization to Indoor Air Criteria (VIAC), it became necessary to expand the mitigation system. Subsequently, Envirologic installed six additional suction points across the facility and installed an additional fan (an OBAR GBR 89 HA Compact Radial Blower) to expand depressurization beneath the entire 47,500 SF structure. The system was completed with visible gauges to alert occupants and the designated system operator of a malfunction; the system was designed to operate continuously with limited inspections or maintenance.\nThe blower systems are currently operating at a pre-fan vacuum between 9 to 14 inches of WC and flow rates ranging from 60 to 80 cubic feet per minute per fan. Performance monitoring results indicate that the mitigation system has generated a negative pressure in excess of the industry standard sub-slab vacuum of a -0.02 WC across the footprint of the structure. The results of effluent testing indicated that the off-gas meets discharge limitations of Michigan's Air Pollution Control Rules; thus, off gas treatment is not required.\nPerformance monitoring results indicated a significant decrease in contaminant concentrations in soil gas beneath the structure. At the request of EGLE, Envirologic completed an addendum to the initial Documentation of Due Care Compliance Report for the facility inclusive of system installation and performance documentation, and monitoring plan with schedules for inspections and required actions. Crown Industrial has since taken control and is performing all operation and maintenance of the system.", "pred_label": "__label__POS", "pred_score_pos": 0.5211041569709778}
{"content": "Flying Private Is More Affordable Than Ever—and Offers Uncrowded Travel Experience\nPrivate aviation is seeing a surge of interest from a new segment of would-be passengers: those seeking to minimize the health risks of air travel during the COVID-19 era. As the country reopens and more flights take to the skies, private aviation terminals like Luxivair SBD allow passengers to bypass the crowds normally associated with air travel. And in the current environment, flying privately is more affordable than ever—in some instances, it can even be more economical than flying commercially.\n“People often think private aviation is an option only for the wealthy or corporations,” says Wendy Bechtel, Luxivair SBD’s manager. “But I encourage anyone who is planning air travel to consider their options—there’s never been a better time to fly private. At Luxivair SBD, passengers can avoid the crowds and hassles they normally encounter during air travel.”\nIn recent years, the private aviation industry has expanded to offer lower-cost options that meet the needs of a wider segment of travelers. Today, reduced fuel prices and legislation in the CARES Act have decreased the costs of flying private even further, making it a viable alternative, particularly for travelers concerned with congested public spaces.\nFor even greater savings, travelers with flexible schedules and destinations can look for “empty leg” flights. After a private jet drops off paying charter passengers, it often needs to go to a different airport to pick up new customers. To offset the costs of repositioning the aircraft, operators may offer seats at a deep discount—sometimes as much as 75% off. Empty legs are particularly cost-effective for those planning to travel as a family or with a small group of friends. When the overall cost of an empty leg charter is divided among a group, the price per person can be on par with flying commercially. To arrange a private charter or search for empty leg flights, check the Air Charter Guide.\nFlying by business jet through an uncrowded private terminal (known as an FBO in aviation terms) has long appealed to celebrities and executives who appreciate the ease and privacy it offers. These benefits have an even broader appeal now:\nPrivate aviation offers speedy check-in, security, and boarding, allowing travelers to bypass large crowds. Those flying privately choose their flight companions, significantly reducing the risk of airborne transmission associated with being confined in close proximity to unknown travelers. At private FBOs, passengers can simply deplane and be on their way, avoiding passage through busy crowded terminals and waiting at luggage carousels. FBOs strictly adhere to the most stringent cleaning procedures.", "pred_label": "__label__POS", "pred_score_pos": 0.7506266832351685}
{"content": "October marked another milestone for OUSA as we held our first-ever full-length, virtual General Assembly. Student delegates from our eight member schools came together to discuss four policies: A Comprehensive Access Strategy, Environmental Sustainability, Responding to COVID-19, and Housing, Transit, & Community Development. Despite the challenges of conducting a four-day conference virtually, our delegates were able to critique policies in breakout rooms, and even had a chance to socialize through a virtual scavenger hunt! The weekend concluded with a closing Plenary session, where delegates debated, amended, and voted on the policy papers—which all passed unanimously, thanks to their hard work. We’re looking forward to sharing these policies over the coming weeks.\nEarlier this month, I represented OUSA at the 2020 provincial Pre-Budget Consultations held by Parliamentary Assistant to the Minister of Finance, Stan Cho, and Minister Jeff Yurek. I took this opportunity to share OUSA’s recommendations to enhance OSAP, expand work-integrated learning opportunities, and increase mental health resources. Students are essential to Ontario’s long-term recovery, and they need support to complete their education, find good jobs, and contribute to rebuilding our economy. A copy of our submission is available here.\nWe were also invited to an announcement on post-secondary student mental health with the Minister of Colleges and Universities, Ross Romano, and the Associate Minister of Mental Health and Additions, Michael Tibollo. The Ontario government announced a $19.25M investment in mental health support for post-secondary students, including additional investments into Good2Talk, a mental health helpline service for students, and increased funding for community-based mental health support. This funding, which includes a $3.25M increase, is an incredible commitment to supporting student mental health.\nAs the Quality of Education campaign has now wrapped up, I’d like to extend a huge thank you to all the students who shared feedback about how COVID-19 has impacted their learning, and who interacted with our posts online, shared our Bingo card, and watched our TikToks! This feedback and engagement helps us improve our advocacy efforts and ensures that OUSA can continue to center student voices as we navigate online and remote learning. Stay tuned for our upcoming report, which will highlight general themes and feedback we heard from students, as well as our recommendations to improve and support online learning.\nLooking forward, we’re excited to take our newly approved policies to our Student Advocacy Conference, which will take place between November 16-19. So far, we have over 30 meetings booked with MPPs, staff, and stakeholders planned, and we’re looking forward to meeting with many more! We will use this opportunity to continue to advocate for accessible, affordable, accessible and high-quality post-secondary education.", "pred_label": "__label__POS", "pred_score_pos": 0.9605036973953247}
{"content": "SVS Risk understands the importance to ensuring the ship protection measures as advised by industry’s Best Management Practices (BMP). When sailing in high risk areas, deterrence and delaying measures should be the primary focus, since confrontation generally lead to unpredictable outcomes and increased risk.\nSVS Risk can either during a long-term task or as a standalone service, at sea or in port provide the necessary guidance and perform a thorough Ship Security Assessment that includes BMP implementation and Master & Crew Anti-Piracy preparedness assessment and training. This service can be part of the Bridge Response Officer service as all Bridge Response Officers are experienced and trained in conducting such surveys and training.", "pred_label": "__label__POS", "pred_score_pos": 0.9970748424530029}
{"content": "A recent public opinion poll released by Transparency International Georgia, a local human rights watchdog, on April 5, shows that the Parliament, the courts and the Central Election Commission enjoy the lowest public trust with 24%, 20% and 20% of respondents, respectively, not trusting these institutions at all.\nThe TI Georgia-commissioned survey was fielded in a period between February 20 and March 5 by the Caucasus Research Resource Center (CRRC). The poll was conducted through nationwide face-to-face interviews (excluding occupied territories) with 2,087 respondents and has an average margin of error plus, minus 2.3%.\nThe poll shows that the Georgian Orthodox Church enjoys the highest trust (55%), followed by teachers with 31%, doctors – 22% and police – 19%. Only 11% of respondents trust the Georgian President, 9% – the Prime Minister, 8% – non-governmental organizations and only 3% – media.\n53% of respondents believe that the judiciary remains under the influence of the ruling party; 35% of respondents think that the institution is corrupt; 50% suppose that it is not fair and 43% consider that there is clan-based rule in the judiciary. 87% of respondents believe that the so called clan is supported by government officials.\nAsked whether influential groups of judges should leave the judiciary, 94% of respondents responded positively. 83% of respondents believe that those judges who have made unfair decisions under pressure in the past should also leave the system.\n46% of respondents think that the courts should be filled with new judges to increase public trust in the judiciary. 41% of respondents believe that the government should not interfere in the judiciary; 26% think that legislation should be amended and 9% consider that Levan Murusidze and Mikheil Chinchaladze should quit the system.", "pred_label": "__label__POS", "pred_score_pos": 0.7752577662467957}
{"content": "This issue of insights is the first of a two-part edition to share definitions, data, and perspectives to further the understanding of the role of trauma at the individual, family, community and system level and perhaps more importantly, how to promote resilience and healing to improve outcomes for children and families. The issue includes insights and recommendations gleaned from interviews with state and county policymakers, pediatricians, judges, social workers, mental health clinicians, and social justice leaders. Stay tuned for our part two issue where we follow up on the recommendations and provide an overview of promising practices.\nThis issue of insights provides an overview of the latest legislative developments in California, including data and perspectives on the policy and practice transformation taking place with the Continuum of Care Reform (CCR). Beyond a comprehensive summary of child welfare state legislation, this issue also includes a discussion on the key provisions of the Family First Prevention Services Act. The issue concludes with recommendations for how to continue bolstering supports for California's children and families.\nThis issue of Insights provides available data and studies on California's housing insecure families, and how housing challenges factor into their trajectory of child welfare involvement both at the front end with family maintenance interventions and removal decisions, as well as case planning for reunification. Included are promising policies and programs that offer important learnings to improve outcomes for families with housing insecurity, as well as recommendations to address the challenges of housing insecurity with the goal of improving outcomes for California’s children and families.\nChild welfare caseworkers hold the complex role of balancing their legally mandated responsibility to protect children from neglect and abuse, with the goal of keeping families together. This issue of\ninsights examines the valuable and complex work performed by California's child welfare workforce and highlights the challenges and opportunities present to strengthen and support the field. insights, Volume XIII - A Matter of Substance: Challenges and Responses to Parental Substance Use in Child Welfare\nThis issue of insights investigates how California captures and reports child welfare entries related to substance use disorder (SUD). It explores the effects of the state’s efforts to integrate child welfare services with behavioral health, the courts, and other programs that support family reunification, and discusses different ways of moving forward with focused services in the state.\nThis issue of\ninsights summarizes recent child welfare reforms, examines the latest data on children in care, discusses challenges and opportunities and outlines recommendations.\nThis issue of\ninsights examines the juvenile court’s role in the child welfare system and provides recommendations on how to best meet the complex needs of children and families in child welfare.\nThis issue of\ninsights offers an overview of data, policy and reform efforts that seek to better understand crossover youth and share accountability for their well-being.\nThis issue of\ninsights looks at what we know (and don’t know) about our caregivers, and provides a primer on the programs that are working to support their success, and ultimately improve the lives of families and children in the child welfare system.\nThis issue examines the current progress and reforms in changing the way Child Welfare is financed by both federal and state agencies.\ninsights, Volume VII: The Promise of the Landmark Katie A. Case and Settlement–Creating New Pathways to Mental Health Services\nThis issue examines the current progress and promise of the Katie A. settlement implementation as a vehicle to improve the delivery of mental health services for children and youth within the child welfare system (2013/14).\nThis issue explores the need to share real time information at both the individual and aggregate levels in order to identify, recognize, and support success including: the current landscape, examples, benefits, and moving forward (2013).\nThis issue focuses on the educational gaps within the foster care population, describing the vulnerability of these students, the missing data links, and the critical supports to achieving better outcomes (2011).\ninsights, Volume IV: African American and Native American Children and Youth Overrepresentation in the Child Welfare System\nThis issue focuses on the over-representation of African American and Native American children in California’s child welfare system. Data show that these two populations are disproportionately represented and have much poorer outcomes than children of other races (2010).\nThis issue provides data on outcomes as well as related policy implications for youth aging out of foster care in California (2010).\nThis issue focuses on permanency for children who are in the child welfare system. Along with safety and well-being, permanency is one of the three critical outcomes that guide all efforts to provide for children who have been abused or neglected (2009).\nThis premier issue examines California’s child welfare outcomes since January 2004, when the state’s new outcomes and accountability system went into effect (2009).", "pred_label": "__label__POS", "pred_score_pos": 0.9614721536636353}
{"content": "Stroke second biggest killer By Paulina Ndalikokule\nA STROKE is a medical condition in which poor blood flow to the brain results in cell death. This is often due to lack of oxygen when the blood flow to the brain is reduced by blockage or rupture of an artery to the brain, and is also a leading cause of dementia and depression.\nThe medical advisor and consultant of OHS & medical projects, Fabian Martens, explained there are two main types of stroke, which are ischemic and hemorrhagic. Ischemic stroke is caused due to lack of blood flow while hemorrhagic is due to bleeding, but both result in parts of the brain not functioning properly.\nPeople at risk for stroke include those who have high blood pressure, high cholesterol, diabetes, and those who smoke and those with heart rhythm disturbances, especially atrial fibrillation, among others.\nStroke is diagnosed by the patient’s symptoms, history, and blood and imaging tests.\nMartens said a stroke is treated as medical emergency and quick intervention may increase a person’s chance of survival and reduce the risk of long-term disability. “Each year, over 795,000 people in the United States have a stroke – that’s about one every 40 seconds,” Martens said.\nHe said understanding what to do when someone suffers a stroke can make a significant difference to their chances of survival or recovery. When dealing with a person on first aid it is important to remain calm while ensuring the surrounding area is safe and that there is no imminent danger, such as from moving vehicles, he added.\n“Talk to the person. Ask them their name and other questions. If the individual is unable to speak, ask them to squeeze your hand in response to questions. If the person does not respond, they are likely unconscious.”\nHe added that if such person is conscious, gently place them in a comfortable position. Ideally, they should be lying on their side with their head and shoulders slightly raised and supported with a pillow or item of clothing.\n“After this, try not to move them. Loosen any tight clothing, such as buttoned-up shirt collars or scarves. If they are cold, use a blanket or coat to keep them warm,” Martens said. “Get to a hospital immediately, avoid waiting to see if your stroke symptoms get better. The faster you can get to the hospital, the better.”\nCertain types of strokes can be treated only in the first few hours, and untreated strokes can lead to permanent damage. In case of an emergency, call for an emergency ambulance rather than driving yourself to hospital, go to an urgent care clinic or ask a family member or friend to drive you.", "pred_label": "__label__POS", "pred_score_pos": 0.6442530155181885}
{"content": "Jersey City, New Jersey – The Confrontation Clause of the United States Constitution is one of the most important provisions in criminal procedure. It requires a criminally accused person to be able to cross-examine the witnesses against him or her. This includes all witnesses, police, civilian and co-defendants.\nIn State of New Jersey v. Michael A. Jackson, the Supreme Court of New Jersey addressed whether a defendant is entitled to cross-examine a testifying co-defendant about the details of the co-defendant’s plea agreement with the State, including the maximum penalties the co-defendant was exposed to. Mr. Jackson and his co-defendants were charged with burglary, theft and conspiracy to commit burglary. One of the co-defendants, Javon Clarke, had reach a plea agreement with the State to testify against Mr. Jackson in exchange for a recommended sentence lower than the maximum exposure. It goes without saying that the maximum exposure is one of the main motivating factors to accept a plea agreement and could be relevant to the testifying co-defendant’s motivation and willingness to lie to secure a favorable plea agreement.\nMr. Jackson’s defense attorney asked Mr. Clarke about his maximum exposure three times, and all three times the court admonished him not to do so. The court also instructed the jury not to consider the question. Ultimately, the jury convicted Mr. Jackson of conspiracy to commit burglary. The Appellate Division affirmed the conviction, but the Supreme Court reversed the conviction on the basis that the Confrontation Clause entitled Mr. Jackson to ask about the maximum exposure because it was relevant to the witness’s potential bias. The Court reached this conclusion after evaluating all the details, including that the witness had lied to the police previously, that he was extended term eligible and could have received up to ten years in prison, and that, as a result of his plea agreement, he received only 180 days in jail. The Court also noted that the State argued the floor of Mr. Clarke’s plea agreement, the 180 days, which made application of the trial court’s ruling against reference to potential sentencing inconsistent.\nTestifying co-defendants who reached plea agreements with the State in exchange for their testimony are common. This decision should ensure that defendants facing testimony of co-defendants will be entitled to exercise the full privilege of the Confrontation Clause to challenge the witness’s bias and motivation to lie.", "pred_label": "__label__POS", "pred_score_pos": 0.5122369527816772}
{"content": "Abstract\nIn recent years, the scale, impact and legality of stop and search in Scotland has been subject to intense critical scrutiny, leading to major legal and policy reform in 2016. Based on these events, including an early unsuccessful attempt by Police Scotland to reform the tactic (the ‘Fife Pilot’), this article presents original theoretical and empirical insights into organizational change in policing. Building on the theoretical perspectives of Chan and Bradford and Quinton on organizational culture and justice respectively, the article sets out a dynamic model of organizational justice in policing. While Scotland has seen significant legislative reform apropos stop and search, we conclude that real change in police practice and culture will require effective leadership and a strong commitment to organizational justice. We also suggest how insights from the analysis might be applied to other jurisdictions and policing fields, with a view to securing more citizen-focused, democratic policing.\nKeywords Cultural change organizational change organizational justice police culture stop and search", "pred_label": "__label__POS", "pred_score_pos": 0.9659854173660278}
{"content": "Managing and Mentoring Leadership Strategies Critical Timing of Two Leadership Strategies\nOur work with entrepreneurial leaders has two phases; initially our role is planner and facilitator of team engagement and then as team strengths are developed and consistently aligned we become an engagement advisor. Regular\nProgress Check Conversations help leaders to make necessary tweaks in leadership strategies and the process helps leaders to know when to transition from manager to mentor. The timely transition of leadership focus has a make-or-break influence on small business performance. Leaders need the right approach at the right time.\nThe Right Time\nAs our clients make the mental leap from a structure of job holders to one of contributor roles, leadership strategies must coincide with every stage of the transition. In the early stages of forming a strengths-based organization, previously untapped abilities are validated and members are dependent upon leaders to continually reinforce alignment of personal strengths with growth goals. Leaders manage the resulting new energy and the integration of individual strengths into collective firepower. Through consistent attention to alignment between people and process, the business culture begins to shift and new energy fuels growth. Through regular dialogue a natural shift in business culture encourages personal and professional development that lends measurable value to organizational growth.\nWhen individuals feel empowered they take initiative to perform their best. This is a time-sensitive aspect of organizational growth and sustainability. If leaders provide too much freedom too early, individuals will default to job-holder status. Readiness should be assessed, engagement illustrated, understood and agreed to, before leaders can expect engaged teams to thrive without their central influence. As an engaged culture takes root in the minds of its individuals, leaders begin to observe their members taking self motivated actions. They demonstrate new motivation toward growth goals based on a clear understanding of their personal potential in the plan. To provide the freedom to contribute, leaders should consider questions rather than answers to growth goals. Mentoring helps individuals explore personal capabilities through the freedom to define and communicate appropriate contributions. Sequentially they take the reins, experience the outcomes of their actions, and shape their best contribution to shared growth. When owners and partners want to ensure long term performance, secure employee retention, and ultimately prepare for retirement from their business, the timely transition from managing people and process, to mentoring business success, is imperative.", "pred_label": "__label__POS", "pred_score_pos": 0.5644322633743286}
{"content": "Abstract\nA long-held view is that stroke causes many distinct neurological syndromes due to damage of specialized cortical and subcortical centers. However, it is unknown if a syndrome-based description is helpful in characterizing behavioral deficits across a large number of patients. We studied a large prospective sample of first-time stroke patients with heterogeneous lesions at 1-2weeks post-stroke. We measured behavior over multiple domains and lesion anatomy with structural MRI and a probabilistic atlasof white matter pathways. Multivariate methods estimated the percentage of behavioral variance explained by structural damage. A few clusters of behavioral deficits spanning multiple functions explained neurological impairment. Stroke topography was predominantly subcortical, and disconnection of white matter tracts critically contributed to behavioral deficits and their correlation. The locus of damage explained more variance for motor and language than memory or attention deficits. Our findings highlight the need for better models of white matter damage on cognition.", "pred_label": "__label__POS", "pred_score_pos": 0.9967799186706543}
{"content": "Many online rating systems represent product quality using metrics such as the mean and the distribution of ratings. However, the mean usually becomes stable as reviews accumulate, and consequently, it does not reflect the trend emerging from the latest user ratings. Additionally, understanding whether any variation in the trend is truly significant requires accounting for the volatility of the product's rating history. Developing better rating aggregation techniques should focus on quantifying the volatility in ratings to appropriately weight or discount older ratings. We present a theoretical model based on stock market metrics, known as the Average Rating Volatility (ARV), which captures the fluctuation present in these ratings. Next, ARV is mapped to the discounting factor for weighting (aging) past ratings and used as the coefficient in Brown's Simple Exponential Smoothing to produce an aggregate mean rating. This proposed method represents the \"true\" quality of a product more accurately because it accounts for both volatility and trend in the product's rating history. Empirical findings on rating volatility for several product categories using data from Amazon further motivate the need and applicability of the proposed methodology.", "pred_label": "__label__POS", "pred_score_pos": 0.9992204308509827}
{"content": "Predictions date back to the beginning of time. As hunters and gatherers, we had to predict several things. We could catch dinner, the best method for detecting it, and what the weather would be like to plan accordingly. We had to predict where predators may attack from and the best defense strategy in case we get attacked. Making short-term predictions is built into our DNA as a form of survival. However, we as humans and the world around us has evolved. The same predictions that kept us alive for thousands of years don't always apply to personal finance and investing rules.\nFinancial Clarity Blog\nHelping people make smart financial decisions.\nEnter your email address to receive the blog in your inbox each week:", "pred_label": "__label__POS", "pred_score_pos": 0.5392651557922363}
{"content": "Diagnosis of C3 Glomerulopathy\nA diagnosis of C3 Glomerulopathy (C3G) requires a renal biopsy and careful review of light microscopy, immunofluorescence and electron microscopy. Broadly, C3G is defined as the predominant staining of C3 on immunofluorescence (IF) when compared to immunoglobulin (intensity >2 orders of magnitude). C3G is classified by electron microscopy findings into dense deposit disease or C3 Glomerulonephritis, depending on the presence or absence of dense osmiophilic intramembranous deposits.\nLight microscopy identifies diverse patterns of glomerular injury that include MPGN, and detect additional features such as crescentic disease or markers of chronic disease such as interstitial fibrosis and tubular atrophy.", "pred_label": "__label__POS", "pred_score_pos": 0.9260203838348389}
{"content": "While the average person may not be concerned with purchasing insurance for the property they are renting, not doing so could be to one’s own detriment. Indeed, no matter how lavish your home may be or how safe your neighborhood is, there is always the potential for unforeseen accidents to occur. That said, the following is an overview of 3 reasons to purchase rental insurance as soon as possible.\nLegal Costs\nOne of the top benefits of rental insurance is that it can help you cover legal costs. For instance, if someone has a slip and fall on your property and become injured, you could be on the hook for hundreds, multiple thousands, or even millions of dollars. However, by purchasing a rental insurance policy, you could be protected against such lawsuits.\nDog Bites\nOn the other hand, if you have a dog, it might be in your best interest to purchase a rental insurance policy. While none of us want to believe that our dog is capable of brutally attacking a human or another animal, these things happen all the time. By purchasing a rental insurance policy, you will be protecting yourself against the unthinkable.\nProtect Your Belongings\nLast but not least, rental insurance can protect your belongings. With coverage that can protect against everything from floods and fires to theft, purchasing a rental insurance policy is one of the best methods of ensuring your belongings are protected at all times.\nOverall, for those who live in McKinney, TX, Parker Preferred Insurance is an excellent option to purchase a rental insurance policy. No matter if you need a little coverage or a lot, one of our highly qualified independent representatives will be there to assist you. Simply call, email, or stop by our McKinney, TX office today. Let Parker Preferred Insurance be your preferred insurance company.", "pred_label": "__label__POS", "pred_score_pos": 0.7962292432785034}
{"content": "Personal Development\nConsultants in diabetes today provide vital clinical and strategic leadership within their Trusts, both as clinical and medical directors, and in a variety of roles in the wider health economy. In addition to continuous professional development, which all healthcare professionals are required to complete, ABCD encourages its members to engage in continuing\npersonal development, providing a range of development opportunities for those who might wish to take on leadership roles in the future.\nABCD offers three distinct personal development opportunities for diabetologists and endocrinologists, namely: the ABCD Consultant Development Programme (CDP), the National Diabetes Consultant Mentorship Programme (NDCMP) and the Consultant Strategic Leadership Programme (CSLP).\nThese programmes, which are accredited as credit-earning short courses through the Academic Institute of Medicine at the University of Wolverhampton are open to all ABCD members. Each programme is designed to provide appropriate, timely and focused personal development for doctors as they progress from specialist registrar to newly-appointed consultant and beyond.\nTo find out more about each of these opportunities and how they might support your own personal development, please click on the buttons below.", "pred_label": "__label__POS", "pred_score_pos": 0.7090688943862915}
{"content": "What’s an IC-DISC and why would you want one?\n$225.00\nDescription\nAbstract: The interest-charge domestic international sales corporation (IC-DISC) is one of the last remaining opportunities that can provide tax incentives for exporters. Historically, IC-DISCs have been used primarily by private companies, but public companies shouldn’t overlook this potentially significant tax break available through the creation of such a corporation. This article explains how an IC-DISC works and its tax benefits.", "pred_label": "__label__POS", "pred_score_pos": 0.6007477045059204}
{"content": "Abstract\nEpstein-Barr virus (EBV) is associated with Hodgkin lymphoma (HL) and can be detected by in situ hybridization (ISH) of viral nucleic acid (EBER) in tumor cells. We sought to determine whether plasma EBV-DNA could serve as a surrogate for EBER-ISH and to explore its prognostic utility in HL. Specimens from the Cancer Cooperative Intergroup Trial E2496 were used to compare pretreatment plasma EBV-DNA quantification with EBV tumor status by EBER-ISH. A cutoff of >60 viral copies/100 μL plasma yielded 96% concordance with EBER-ISH. Pretreatment and month 6 plasma specimens were designated EBV(-) or EBV(+) by this cutoff. Patients with pretreatment EBV(1) plasma (n = 54) had inferior failure-free survival (FFS) compared with those with pretreatment EBV(-) plasma (n = 274), log-rank P = .009. By contrast, no difference in FFS was observed when patients were stratified by EBER-ISH. Pretreatment plasma EBV positivity was an independent predictor of treatment failure on multivariate analyses. At month 6, plasma EBV(+) patients (n = 7) had inferior FFS compared with plasma EBV(-) patients (n = 125), log-rank P = .007. These results confirm that plasma EBV-DNA is highly concordant with EBER-ISH in HL and suggest that it may have prognostic utility both at baseline and after therapy. This trial was registered at www.clinicaltrials.gov as #NCT00003389.\nASJC Scopus subject areas Biochemistry Immunology Hematology Cell Biology", "pred_label": "__label__POS", "pred_score_pos": 0.6943666934967041}
{"content": "Confession – I was NOT enamored with the extended rest last week. I expected to enter the Friday workout ready and raring to go and could not believe how heavy the barbell felt. I opted for the lighter, shorter option of the workout and consoled myself with the knowledge that The Siskiyou Challenge, a multi-leg multi-sport relay race was pending the following day, and this could serve as a taper (a concept I have considered often, but implemented only rarely, never wanting to miss out on the fun just because of the next day’s race). The evening brought heavy rain, and I embraced the quiet energy of the day.\nRelaxing – Reluctantly\nThe rain continued into the morning, but the weather was kind overall for the bike, kayak, bike, run, bike, run events. It was a fantastic day with so many members of our community, particularly from our gym, participating in the race. A social event composed of a variety of physical activities, against the back drop of the beautiful landscape of our town, complete with live music and delicious home-grown food might come close to a perfect experience. Capped off by a gymnastics performance where biggest, middlest and littlest demonstrated their hard-earned skills in jumping, flipping and dancing, the day was bursting with energy and enjoyment.\nRelaxing Recreationally\nAs Sunday arrived, I relished the quiet calm of mobility to start the day (relaxing respectfully) and began to find a rhythm again in the gym with workouts, inspired by the enthusiasm of my husband and fellow athletes along with our children, who are always up for a challenge. Welcoming back the soreness in my muscles as a feeling of being alive and building strength, I began to convince myself that rest days were not for me, that I had done my due diligence and would return to the omission of them from my schedule going forward.\nRelaxing – Relatively\nOur gym social Monday was a great celebration of achievements from both the relay race as well as a weightlifting meet for our coaches and I espoused my new philosophy, noting that it might not be the right choice for everyone, but for me, the extended, total rest intervals were detrimental rather than therapeutic. Ironically, that same day, an article I had written for a local publication was released noting\nRest Days and Recovery Help to Get You Fit! Thankfully, I had detailed the option of active recovery and encouraged outdoor, playful activities, so was saved from hypocrisy by the capacity for utilization of the many fantastic local resources and would be able to achieve restfulness in the way of cycling, swimming, paddling, running, hiking or playing in the beautiful landscape of Southern Oregon.\nRelaxing Reasonably\nBy Tuesday, I was back in action for an extended gym celebration – participating in classes as a new coach took the reins and celebrating the anniversary of my first-ever due date with a workout that shares a name with biggest. An unexpected add-on clinic on a usual day off was balanced with opportunity to sneak in a bike ride through town and I regained the sense of contentment that had been missing in the week prior.\nRelaxing – Remotely\nI committed mentally to adjusting my rest day goal and entered into Wednesday ready to work. Thanks to the formatting of the workout, I was able to both coach and participate, utilizing the rest intervals (relaxing resourcefully!) to complete the prescribed movements and found myself drawn to the after-work with fellow athletes instead of the writing I had originally intended. Trusting the spirit of the moment, I finished the session, replete with conversation and encouragement before setting forth into an extended clinic day. The usual evening mobility session was precluded by the addition of extra patients and, instead, my unwind was a brief walk to town and a delicious dinner, recapping with my uncle, who graciously came to town to represent our elder generation at the children’s Grandparent’s Day, overriding the time I planned for writing in place of the morning session, leading me to set an early alarm for the following morning,\nRelaxing Relationally\nWhen the tones sounded at 0425, I was overcome by a very emotional response – an internal turmoil of awareness that I did\nnot have the energy to coach a class with the enthusiasm I would want for my athletes and wondering how I was going to survive the extended clinic day to follow, wishing desperately for a few more hours of sleep. After brushing my teeth and reaching for my leggings, I had a sudden realization – it was THURSDAY! The one day I am exempt from the coaching schedule (thanks to the forethought of my former self, recognizing that we need a regular pause from activities to maintain a positive spirit) and that a few more hours of sleep were, indeed, possible. This was a true moment of awakening and acceptance for me in the week – speaking to the need for rest as well as flexibility in timing of that respite with capacity to honor myself, past and present, in order to support the best of myself in the future.\nRelaxing – Relievedly\nOwning the necessary vulnerability of the experience, I shared the wake-up distress and immediate rejoicing on discovery of the built-in rest-from-responsibility-in-the-gym-day; many took this to mean I feel burdened by coaching, which is absolutely not the case. Quite the contrary, I usually feel invigorated and inspired, eager to work with athletes, explore the boundaries of fitness, witness progress, develop new goals and celebrate personal victories. Consequently, this moment of feeling unable to enter into a typically welcome experience was the aggressive wake-up call needed. To clearly see that a limit had been reached and, in order to maintain that inspired state and the enthusiasm my athletes deserve, I needed to pause, reset and replenish. What might historically have been perceived personally as a failure, in light of this rest-day challenge and dedicated exploration of that sweet spot among mind, body, spirit, it was a most needed moment of growth. Synthesizing the considerations I have carried in the previous weeks, I am motivated to continue with the challenge.\nRelaxing Resolutely\n(with an open mind on the details)\nA gentle run on Thursday evening, supporting active recovery, brought me to the gym for a lecture on\nMind-Body-Inseparable with two of our athletes, who are teachers at a local meditation center. As they led us all in reflection, I neared that integral space of mind, body and spirit and landed smack dab in the middle upon hearing their testimony that the act of being fully present in the body during time in the gym was a truly unique experience, allowing us to be free of the busy mind while still mindful of the active body. Such a profound concept and one I honestly never acknowledged – perhaps the only time in the day when we do not allow ourselves to be swept up into the current of “what’s next” and truly feel “here I am, now.”\nRelaxing, Reciprocally\nWith a closing statement on the use of meditation in our daily lives, it was advised that we can always return to the breath, as if it was the only thing that mattered and because it is the one thing that does, above all else. To achieve this, we practiced a simple deep breath in, thinking of nothing but the breath, and another out, followed by the direction to relax – relentlessly.\nMay we find the balance point for ourselves by trusting instincts, remaining open to insights and adapting to shifts in the experience, finding reinforcement through the power of relaxing – responsibly, responsively and reliably.\nBest,\nFitMamaDOc", "pred_label": "__label__POS", "pred_score_pos": 0.789824366569519}
{"content": "Awaleha Nutrients enriched, Ayurvedic energy booster\nChyawanprash is one of the most popular and individual friendly classical ayurvedic recipes as \"health food\" for restoring good health and vitality and ensuring faster recovery, especially from long-term chronic ailments. Aimil Chyawanprash has got a strong scientific base of being Anti-oxidant, Immunomodulator, Adaptogenic, Anti-stress, Digestant, Anabolic, Metabolic Regulator and a Rich Source of Nutrients helping improve energy levels. The utility of Chyawanprash can be established by its continuous existence in health management for centuries. Chyawanprash Awaleha is suitable for all age groups under all seasons, including those exposed to physical and mental stress and remains the preparation of choice for its benefits to check various conditions like a cough and cold in altering weather.\nAimil Chyawanprash is manufactured under strict compliance of GMP (Goods Manufacturing Practices) as described under the ISO 9001: 2015 provisions and the rules under the Drugs & Cosmetics Act in a purely healthy and hygienic environment at its manufacturing unit equipped with ultra modern facilities, making use of components of the highest standard quality.\nDosage For 2-5 years: 1/4 teaspoonful (3 grams approximately) once a day. For 6-11 years: 1/2 teaspoonful (6 grams approximately) once a day. For 12 years and above: 1 teaspoonful (12 grams approximately) once a day. Dosage can be increased as directed by the physician.", "pred_label": "__label__POS", "pred_score_pos": 0.8876471519470215}
{"content": "Abstract 18F-N-[3-bromo-4-(3-fluoro-propoxy)-benzyl]-guanidine ( 18F-LMI1195) is a new PET tracer designed for noninvasive assessment of sympathetic innervation of the heart. The 18F label facilitates the imaging advantages of PET over SPECT technology while allowing centralized manufacturing. Highly specific neural uptake of 18F-LMI1195 has previously been established, but the retention kinetics are not yet fully understood. Methods: Healthy New Zealand White rabbits were studied with 18F-LMI1195 using a small-animal PET system. Dynamic 40-min chest scans were started just before intravenous bolus injection of 18F-LMI1195. Imaging was performed under norepinephrine transport inhibition with desipramine pretreatment, a 1.5 mg/kg desipramine chase administered 10 min after tracer injection, and saline treatment of controls. As a reference, cardiac uptake of 11C-hydroxyephedrine and 123I-metaiodobenzylguanidine ( 123I-MIBG) was examined by PET and planar scintigraphy, respectively. Results: Cardiac uptake of all 3 tracers was inhibited by pretreatment with desipramine. Stable cardiac tracer retention was delineated by dynamic PET in control rabbits for 11C-hydroxyephedrine (washout rate, 0.42% ± 0.57%/min) and 18F-LMI1195 (washout rate, 0.058% ± 0.28%/min). A desipramine chase increased 11C-hydroxyephedrine washout from the heart (2.43% ± 0.15%/min, P < 0.001), whereas 18F-LMI1195 washout was not influenced (0.059% ± 0.11%/min, not statistically significant). Additionally, a desipramine chase did not change the cardiac 123I-MIBG uptake (delayed heart-to-mediastinum ratio, 1.99 ± 0.12 (desipramine chase) vs. 2.05 ± 0.16 (controls), not statistically significant). Conclusion: In vivo norepinephrine transporter (NET) blockade with desipramine confirmed specific neural uptake of 18F-LMI1195, 11C-hydroxyephedrine, and 123I-MIBG in rabbit hearts. 11C-hydroxyephedrine cardiac retention was sensitive to a NET inhibitor chase, indicating a cycle of continuous NET uptake and release at the nerve terminals. In contrast, 18F-LMI1195 and 123IMIBG demonstrated stable storage at the nerve terminal with resistance to a NET inhibitor chase, mimicking physiologic norepinephrine turnover. Keywords C-hydroxyephedrine F-LMI1195 Imetaiodobenzylguanidine Positron emission tomography Sympathetic nerve ASJC Scopus subject areas Radiology Nuclear Medicine and imaging", "pred_label": "__label__POS", "pred_score_pos": 0.5381889343261719}
{"content": "Description\nBackground: Hydroxychloroquine has not been associated with improved survival among hospitalized COVID-19 patients in the majority of observational studies and similarly was not identified as an effective prophylaxis following exposure in a prospective randomized trial. We aimed to explore the role of hydroxychloroquine therapy in mildly symptomatic patients diagnosed in the outpatient setting. Methods: We examined the association between outpatient hydroxychloroquine exposure and the subsequent progression of disease among mildly symptomatic non-hospitalized patients with documented SARS-CoV-2 infection. The primary outcome assessed was requirement of hospitalization. Data was obtained from a retrospective review of electronic health records within a New Jersey USA multi-hospital network. We compared outcomes in patients who received hydroxychloroquine with those who did not applying a multivariable logistic model with propensity matching. Results: Among 1274 outpatients with documented SARS-CoV-2 infection 7.6% were prescribed hydroxychloroquine. In a 1067 patient propensity matched cohort, 21.6% with outpatient exposure to hydroxychloroquine were hospitalized, and 31.4% without exposure were hospitalized. In the primary multivariable logistic regression analysis with propensity matching there was an association between exposure to hydroxychloroquine and a decreased rate of hospitalization from COVID-19 (OR 0.53; 95% CI, 0.29, 0.95). Sensitivity analyses revealed similar associations. QTc prolongation events occurred in 2% of patients prescribed hydroxychloroquine with no reported arrhythmia events among those with data available. Conclusions: In this retrospective observational study of SARS-CoV-2 infected non-hospitalized patients hydroxychloroquine exposure was associated with a decreased rate of subsequent hospitalization. Additional exploration of hydroxychloroquine in this mildly symptomatic outpatient population is warranted.", "pred_label": "__label__POS", "pred_score_pos": 0.814697265625}
{"content": "Vigod et al, 2019. Brain Stimulation. A randomised sham-controlled trial. Transcranial direct current stimulation (tDCS) for depression in pregnant women. 20 participants, all pregnant between 14-32 weeks. There were no serious adverse effects, and no serious pregnancy complications. End-point depression scores were lower, but not significantly so, in the tDCS group compared to the sham group. 4 weeks after giving birth, 75% of those who had received tDCS were in remission, compared to only 12.5% for sham-tDCS.", "pred_label": "__label__POS", "pred_score_pos": 0.9993351101875305}
{"content": "Info in Miami & Nationwide\n\"Colson Hicks Eidson is recognized as one of the top litigation firms in the country, handling local, national and international litigation for a wide range of clients.\" - Chambers USA\nDefective Toys Could Seriously Harm Your Child – Tips For Parents\nNo parent should ever have to worry about the toys they purchase causing harm to their child. Unfortunately, we have all heard the nightmares of defective toys causing substantial\ninjuries to children. When this happens, parents are often able to secure compensation from the companies or manufacturers responsible for the defective toy. However, product liability attorney at Colson Hicks Eidson believes that the most effective way to keep your child safe is to be aware of what to look out for so you can avoid purchasing a defective toy in the first place. Safety Tips To Keep Defective Toys Away From Your Kids\nYou cannot rely on simply watching for recalls of toys when working to determine whether or not the items you purchased for your child are safe. The reality is that many recalls in warnings do not happen until a dangerous or defective toy has already caused harm to a significant number of children. According to the US Consumer Product Safety Commission, there were an estimated 226,100 toy-related injuries in 2018 amongst children younger than 15 years of age.\nThere are various factors that parents can take into consideration when determining whether or not a toy may be safe for their child.\nAvoid any toys marketed on the internet that lack warnings, age recommendations, or instructions. Even if a product has great reviews on online platforms such as Amazon, please understand that these reviews can be manipulated. Avoid battery-operated toys for children under the age of 8, as these batteries may overheat, leak, or explode. Avoid any toys with “hair” or “fur.” This includes dolls and stuffed animals that often have loose parts that a child may inhale or eat. You should not allow your child to play with a toy that has any strings longer than 6 inches or with removable objects at the end of laces or strings (like bells or knobs). Do not buy any toys that are meant to be strung across playpens or cribs, as these could strangle a child when they are unsupervised. Avoid “bonus” toys that are given away with other product lines such as clothing, books, food, etc. Often, these toys are sold with no warnings or instructions. Toys with small parts need to be avoided, as these parts can become choking hazards. Let Us Help If Your Child Has Been Injured By A Defective Product\nIf your child has been injured by a defective toy, you need to seek assistance from an attorney as soon as possible. At\nColson Hicks Eidson, we are ready to provide you with an award-winning product liability team that can conduct a full investigation into the incident. Our goal is to secure the compensation you in your child are entitled to, including coverage of any medical bills, lost wages if you cannot work while you care for your child, pain and suffering damages, and more. When you need a product liability attorney in Florida or elsewhere throughout the US, you can contact us for a free consultation by clicking here or by calling us at 305-476-7400.", "pred_label": "__label__POS", "pred_score_pos": 0.6396697759628296}
{"content": "Motivair Corporation recently relocated its corporate headquarters to a larger 50,000 SF facility, with plans to expand up to 100,000 SF\nReliable cooling technology serves as a critical resource that directly impacts product and quality, leading to reduced waste and increased output. Cooling system data can be recorded and analyzed in real time, allowing operators to trend and adjust facility operations to maximize uptime and reduce operating costs. By integrating and analyzing production line data, improvements can be made plant-wide on quality, costs, waste.\nModular Low Ambient Air Source Heat Pump can help meet design requirements for decarbonization & electrification. Delivers 110*F hot water at 5*F\nDOCUMENT TYPE SIZE UPDATED DOWNLOAD\nMPC-W | Compact Water-Cooled Chillers 1 MB April 2020 DOWNLOAD\nClosed Loop Cooling Systems| Pump Stations 0.8 MB January 2020 DOWNLOAD\nCTC | Low Temperature Process Chillers 0 MB October 2019 DOWNLOAD\nHeat Recovery Chillers MHR 200-950 1.4 MB October 2019 DOWNLOAD\nMHR | Air Cooled and Water-Cooled Heat Recovery Chillers 1.3 MB January 2020 DOWNLOAD\nMLC-A | Air-Cooled Chillers 1.2 MB October 2019 DOWNLOAD\nMLC-AD | Adiabatic Chillers 1.2 MB October 2019 DOWNLOAD\nMLC-FC | Free-Cooling Chillers 1.2 MB October 2019 DOWNLOAD\nMLC-SC-A | Air-Cooled Scroll Chillers 1.5 MB October 2019 DOWNLOAD\nMLC-SC-FC | Free-Cooling Scroll Chillers 1.5 MB April 2020 DOWNLOAD\nMPC-A | Air-Cooled Chillers 0 MB January 2020 DOWNLOAD\nMPC-FC | Free-Cooling Chillers 0 MB January 2020 DOWNLOAD", "pred_label": "__label__POS", "pred_score_pos": 0.677757978439331}
{"content": "Chapter 19. Do Docs Better: Integrating Documentation into the Engineering Workflow\nAcross the software industry, confidence in engineering documentation is low. Stack Overflow’s 2016 developer survey ranked documentation as the number two challenge facing developers.\nThis is a problem. Missing, incomplete, or stale or inaccurate documentation hurts development velocity, software quality, and—critically for SREs—service reliability. And the frustration it creates can be a major cause of job unhappiness for developers.\nDocumentation takes time and effort, and this is especially challenging for SREs. SREs often spend 35% of their time on operational work, which leaves only 65% for development. Time spent on documentation needs to come out of the development budget, and this is challenging if there’s a perception that creating and maintaining documentation is grunge work that might not be recognized or rewarded during performance review and promotion processes.\nHow can this be changed? How do you make your organization understand the value of engineering documentation, encourage engineers to create and maintain it, and convince management and leadership that doing so is an activity worthy of recognition, funding, and reward?\nAt Google, we’re lucky to have a strong technical writing organization, but our writers tend to focus on high-impact, high-visibility ...", "pred_label": "__label__POS", "pred_score_pos": 0.7551590204238892}
{"content": "Drinking water is recognized as a source of lead (Pb) exposure. However, questions remain about the impact of chronic exposure to lead-contaminated water on internal dose. The objective of the study was to estimate the relation between a cumulative water Pb exposure index (CWLEI) and blood Pb levels (BPb) in children aged 1 to 5 years.\nOriginal Source", "pred_label": "__label__POS", "pred_score_pos": 0.9995753765106201}
{"content": "Clustered water is vital to everyone's health. A significant portion of our bodies are made from water, but not just ordinary water. NHT Global’s Cluster X2 has been created to benefit the body with increased and more efficient cell hydration. It is now adequate, independent research on the bioactivity of clustered water (water clusters)", "pred_label": "__label__POS", "pred_score_pos": 0.6421756744384766}
{"content": "This track is designed for students to gain experience in modelling, analysing, and solving complex decision-making situations. The track is suitable for careers in the emerging field of data-driven decision making, using tools and techniques in both the descriptive domain (statistics and predictive analytics) and the prescriptive domain (optimisation and reinforcement learning). Understanding multi-player behaviours (social network evolution and game theory) is also valuable when developing such applications as energy pricing systems, trading platforms, and resource-sharing systems.\nSelect 3 from # Half term course\nFor more information regarding the Business Analytics and Operations Research focus track, please contact Georgios Piliouras.", "pred_label": "__label__POS", "pred_score_pos": 0.7693217992782593}
{"content": "Abstract\nWe present a dynamical model that successfully explains the observed time evolution of the magnetization in diluted magnetic semiconductor quantum wells after weak laser excitation. Based on the pseudo-fermion formalism and a second-order many-particle expansion of the exact p–d exchange interaction, our approach goes beyond the usual mean-field approximation. It includes both the sub-picosecond demagnetization dynamics and the slower relaxation processes that restore the initial ferromagnetic order in a nanosecond timescale. In agreement with experimental results, our numerical simulations show that, depending on the value of the initial lattice temperature, a subsequent enhancement of the total magnetization may be observed within the timescale of a few hundred picoseconds.", "pred_label": "__label__POS", "pred_score_pos": 0.9439941048622131}
{"content": "According to the research data analysed and published by ComprarAcciones.com merger and acquisition (M&A) deal activity in the pharmaceutical sector rose by 17% in H1 2020, disregarding the economic toll of the global pandemic.\nIt saw a total of 41 deals during the period, but the Q2 2020 deal value total of $3.3 billion was the lowest quarterly total since Q1 2018.\nAccording to PwC, the pharma subsector posted a drop of 56% in deal value from H2 2019 to H1 2020. For the PLS sector as a whole (pharma, biotech and medical devices), the decline in deal value was a massive 87.2% during the same period.\nPharma and Life Sciences (PLS) M&A Total Deal Value Sank from $272.9B to $35B YoY\nThe total deal value for the pharmaceutical subsector in H1 2019 was $100.1 billion. In contrast, its total deal value in H1 2020 was valued at $7.7 billion.\nThe PLS sector had a total of 99 deals valued at $35 billion in H1 2020. In H2 2019, the figures were higher, with 129 deals valued at $86.5 billion. H1 2019 was even bigger, with 119 deals valued at a remarkable $272.9 billion.\nMeanwhile, for the healthcare industry as a whole, H2 2020 started off with 13 deals valued at $1 billion+ according to S&P Global.\nOn the other hand, based on a report from Global Data, the global M&A deal value started on a downtrend in Q1 2020. It went from $151.2 billion to $129.9 billion from February to March. Another study from S&P Global shows that the decline carried into Q2 2020, with a 35% drop in deal volume. Similarly, total transaction value dropped by 40%, the highest drop since 2015.\nComparing H1 2020 to H2 2019, the total deal volume sank by 32% year-over-year (YoY) from 10,155 deals to 6,938 according to Merger Market. Deal values sank by 53%, from $1.9 trillion to $901.6 billion during the same period.", "pred_label": "__label__POS", "pred_score_pos": 0.9028119444847107}
{"content": "Creditors Calling? Put An End To Harassing Phone Calls\n2014-03-14\nMany people struggling from debt issues are afraid to answer the phone or open their mail. As debt issues get worse, the contact with creditors can become more frequent and more demanding. This is especially true if your debt has been transferred to a collection agency. The Ministry of Consumer Services outlines some useful information regarding collection agencies and debt collection for consumers. Here's what you need to know:\nThey should contact you initially with a written notice through regular mail Six days following written notice, they can then contact you by phone or email They cannot contact you more than three times in seven days (contact refers to an actual conversation not voice mail messages or missed calls) They can contact you on Sunday only between 1:00 – 5:00 p.m. They cannot contact you after 9:00 p.m. or before 7:00 a.m. from Monday to Saturday They cannot contact you on a statutory holiday They cannot use threatening or profane language and / or use undue or excessive pressure Can collection agencies call your family and friends?\nA collection agency can contact family and friends to enquire about your address or telephone number if they have been unable to reach you. Ignoring telephone calls and letters may lead the creditor to seek other ways to reach you as they attempt to collect your debt.\nHow can I get a creditor to stop calling?\nTo get a creditor to stop calling you, you need to make a mutually agreeable payment arrangement. Once an agreement has been reached, be careful not to default on any of the scheduled payments or you could be subject to legal action. If you have multiple accounts in collection, you must make separate agreements with each agency.\nWhat if I can't afford the payments?\nIf you cannot afford to pay your debt, it's time to contact MNP to discuss your options. We can help you negotiate a plan with your creditors based on what you can afford to pay each month. To put an end to harassing phone calls and debt stress, contact MNP today.", "pred_label": "__label__POS", "pred_score_pos": 0.5841994285583496}
{"content": "The Ancient Egyptians first created star charts from the 3rd millennium BC. These later morphed into a 12-sign zodiac between 300 BC to 30 BC.\nThe Egyptian zodiac drew on those of the Babylonians and Ancient Greeks, but it retained its own focus and even its own cycle.\nWhile Western astrology has roughly one sign for each 30-day period, Egyptian astrology follows a different path.\nSome signs show up two to four times in a single year. Read on to find out about the Egyptian gods and how they influence each zodiac sign.\nUsing your astrological sign can give you quite a lot of insight into your personalities. You won’t believe what the science of\nNumerology can reveal about you as well!\nThat’s right, the\nnumerology of your birth date, regardless of what month you were born, can reveal surprising information about your personality. Egyptian Zodiac The Nile Dates: January 1 to 7; June 19 to 28; September 1 to 7; November 18 to 26\nInterestingly, the first sign is not a god but rather the Nile itself. Without the yearly flooding, there could be no life.\nPeople born during this time are affectionate and loving, and they have an easygoing personality.\nThese individuals typically have a gentle temperament that pairs well with their observant nature. However, their passions can get out of control and lead to unpredictable mood swings.\nAmon-Ra Dates: January 8 to 21; February 1 to 11\nAmon-Ra is the ruler of the gods, overseeing the sun, the universe and all beings in it.\nPeople born during this time have inherent leadership qualities. They are naturally curious and optimistic, and they have firm opinions about all aspects of life.\nThese individuals have a deeply humanitarian nature that thrives on generosity. At times, though, their stubbornness and ego can get the better of them.\nMut Dates: January 22 to 31; September 8 to 22\nThey can be wonderful parents, and they find success as teachers, nurses and other nurturing roles. Their downfall is their deep emotions, which can make them vulnerable.\nGeb Dates: February 12 to 29; August 20 to 31\nGeb is the Earth god, linking the land with the heavens. People born during this time are sensitive and intuitive.\nThey possess strong compassion for the land and community, and they constantly monitor their emotions and the emotions of others.\nThis sensitivity can lead people to take advantage of thoughts and actions offered.\nOsiris Dates: March 1 to 10; November 27 to December 18\nOsiris is the god of rebirth and the underworld.\nPeople born during this time can be both charismatic and vulnerable. They have a lot of passion for new projects, and their leadership and intelligence sees them through.\nAt the same time, their tempers can flair up and lead to frustration and impatience. These individuals don’t always take criticism well, and they can freeze up under pressure.\nIsis Dates: March 11 to 31 ; October 18 to 29; December 19 to 31\nIsis is the goddess of medicine, magic and marriage.\nPeople born during this time have straightforward personalities. They are energetic and honest, with a strong confidence.\nThese individuals expect much from themselves and others, and they are sometimes misunderstood. This misunderstanding can cause hurt feelings until others get to know the real them.\nThoth Dates: April 1 to 19; November 8 to 17\nThoth is the god of communication, wisdom and the moon.\nPeople born during this time possess strong creativity. They overflow with ideas, experiences and lessons, which makes them natural teachers.\nThese individuals are good at maintaining relationships, and they are fiercely loyal. Their downfall is being unable to let go of hurt once betrayed.\nHorus Dates: April 20 to May 7; August 12 to 19\nHorus is the sky god in charge of protecting Egypt and the king.\nPeople born during this time are hardworking and self-assured. Possessing a caring, community-oriented nature, they are passionate about changes that improve the greater good.\nTheir stubbornness can work against them sometimes, leading to inflexibility and jealousy.\nAnubis Dates: May 8 to 27; June 29 to July 13\nAnubis is the guardian to the underworld, helping people transition from life to death. People born during this time are creative, tolerant and compassionate.\nThey see the good and bad in life, and they work hard to understand others. At the same time, their introspective nature can make them moody and prone to emotional shifts.\nSeth Dates: May 28 to June 18; September 28 to October 2\nSeth is the god of chaos, metamorphosis and the desert.\nPeople born during this time are best described as life-long soul searchers. They seek out adventure and change, always seeking what makes them happiest.\nThey are dreamers, but they’re also perfectionists. Both of these traits can lead to tensions until they find their ideal niche.\nBastet Dates: July 14 to 28; September 23 to 27; October 3 to 17\nBastet is the warrior goddess of fertility, women and protection against evil.\nPeople born during this time seek out peaceful, balanced lives. They are drawn to pleasure, preferring things that bring joy rather than frustration. These individuals possess strong loyalty, and they work hard to protect others.\nSekhmet Dates: July 29 to August 11; October 30 to November 7\nSekhmet is the goddess of war, healing and the sun.\nPeople born during this time are perfectionists who see the world in black and white.\nThey are self-disciplined and have good leadership qualities, but they have a down-to-earth, practical personality as well. These individuals can have a bit of an ego at times, which may cause tension.", "pred_label": "__label__POS", "pred_score_pos": 0.5381580591201782}
{"content": "The coronavirus has upended ordinary life as we know it. Many people are experiencing financial hardships and have questions regarding their personal finances. With Congress recently approving a $2 trillion economic stimulus package, let’s take a deep dive into what laws have been altered and how this may affect you.\nApproximately $250 billion has been earmarked for personal cash payments. Individuals are eligible for checks up to $1,200 and married couples filing jointly are eligible for checks up to $2,400, with an extra $500 for each child. Eligibility for recovery checks is reduced starting at $75,000 in 2018 income for individuals and $150,000 in 2018 income for joint filers. Individuals with 2018 income exceeding $99,000 and joint filers with 2018 income exceeding $198,000 are ineligible.\nOther changes include:\n- The tax filing deadline of April 15 has been extended to July 15. Individuals required to make estimated tax payments can now postpone them to October 15.\n- Retirement account rules are now loosened. Older Americans who are subject to mandatory minimum distributions from their retirement accounts can now keep capital invested instead of being forced to cash out for 2020.\n- The bill waives the 10% penalty on coronavirus-related early distributions from 401(k)s and IRAs, which applies to distributions made at any time during 2020.\nAs you can see, in addition to personal payments, the coronavirus has impacted everything from retirement accounts to tax filing dates.", "pred_label": "__label__POS", "pred_score_pos": 0.9662953019142151}
{"content": "Restrictive Policies a Barrier to Cross-Border Open Science – Open Science in the Nordics: Legal Insights published\nThe most recent deliverable from EOSC-Nordic Work Package on Legal Issues, Policies, and Sustainability is out! By engaging with four use cases developed in Work Package 5 of EOSC-Nordic, the deliverable provides insights into the legal and legislation related issues confronted by cross-border research.\nThe fundamental goal of EOSC is to support European research by promoting the sharing of research data sets, enabling data reuse and collaboration. For this to happen, legal frameworks and processes must be in place, in particular, when data sharing happens across borders. Deliverable 2.3: Open Science in the Nordics: Legal Insights is a case-based study of legal frameworks and their impact on cross-border research data collaboration. The study aims to inform policymakers about the sharing and safe processing of open and sensitive data across borders. The study will also support the evolution of EOSC Governance by supporting EOSC Implementation and complements the work of the FAIR Working Group in assessing the European legal framework for EOSC.\nBased on data sharing in use cases PM Heart, NorMedPregCCC, NICEST 2, and DeepDive, there are three main takeaways from the study. When sharing data, compliance with the regulation on personal data protection, intellectual property rights, and licensing must be taken into account. This restricts the sharing of in particular sensitive data such as medical records. However, maybe surprisingly, the study finds that in many situations,\nin many cases, legislation is not a barrier to cross-border data sharing for research.\nThe study finds that\norganizations often have policies for data sharing more restrictive the required by legislation. Reasons for this include lack of perceived benefit of sharing, perceived risk of exposure, and lack of legal insight and expertise. As a result, researchers might not be encouraged to share data due to the lack of benefits or legal expertise. To avoid such barriers to cross-border data sharing related to legal process and policy, a clear legal framework for data sharing is required to promote pre-defined policies in data ownership and rights and create a culture of data sharing and encourage less protective polities of the data custodians. For this to happen, support is required for tackling legal issues and processes by both research institutions and individual researchers. Having such support in place may be essential to reach the goals of EOSC.\nThis deliverable is the first one of two EOSC-Nordic deliverables studying the legislative framework related to EOSC activities. The next deliverable will provide policy recommendations.\nWould you like to read more? Visit the full document.", "pred_label": "__label__POS", "pred_score_pos": 0.9844332337379456}
{"content": "Dec 15, 2020 - 4:30 PM to 7:45 PM\nPreschool, Elementary, Middle School, High School\nTeachers, Social Workers, Psychologists, Speech Pathologists, School Leaders, Level III Teaching Assts.\nAs the COVID-19 pandemic impacted the nation, educational professionals were forced to adapt to online platforms and provide instruction with little guidance and virtually no time to prepare.\nAs the educational community continues to innovate new strategies to best meet the needs of students with disabilities based on ever-changing conditions, alternatives for typical in-person activities and best practices have started to emerge. During this workshop, the presenter will describe strategies and technologies to enhance the remote classroom to optimize students’ academic learning time. Participants will learn innovative ways to engage students with special needs by incorporating opportunities to respond, manage off-task behaviors while promoting on-task behaviors, and facilitate effective instruction while considering IEP goals and existing curricula. Additionally, participants will be provided with time for application to their own professional setting and discussion with others.", "pred_label": "__label__POS", "pred_score_pos": 0.935893714427948}
{"content": "People who use essential oils for high blood pressure often recommend:\nBergamot\nIn a small study including 52 participants, researchers tested whether inhaling an oil blend containing bergamot could help reduce hypertension.\nThe blend also included lavender and ylang-ylang.\nBased on their results, the team concluded that essential oils may help reduce high blood pressure.\nCitronella\nPeople traditionally use citronella oil as a mosquito repellent, but it may benefit the health of the heart.\nA small 2012 study, published in the\nJournal of Health Research, reports that inhaling citronella vapors may significantly reduce a person’s blood pressure, heart rate, and respiratory rate. Clary sage\nIn the study, clary sage oil reduced the participants’ heart rates while they were undergoing urodynamic examination.\nFrankincense\nFrankincense essential oil is a popular component of Eastern medicine. In addition to having anti-inflammatory properties, it may also help combat anxiety and similar issues.\nThese effects may help reduce high blood pressure. However, it is possible for people to have high blood pressure even when they feel relaxed.\nLavender Neroli\nResearchers have found that neroli essential oil, blended with lavender, ylang-ylang, and marjoram could reduce stress and blood pressure in people with prehypertension and hypertension.\nRose\nRose oil may have calming effects.\nOne study has reported that applying rose oil to the skin can reduce blood pressure, heart rate, breathing rate, blood oxygen saturation levels, and skin temperature.\nSweet marjoram\nResearchers behind a small 2017 study observed “remarkable changes” in the blood pressure and heart rates of participants who inhaled sweet marjoram essential oil.\nA 2012 study mentioned above also used a blend containing marjoram oil and found similar results.\nValerian\nValerian is a potent relaxing agent and a common ingredient in many natural products that claim to enhance sleep and promote calmness in humans and pets.\nThe European Medicines Agency points to a long history of valerian as a sleep aid before noting that the essential oil can be used to treat mild mental stress and promote sleep.\nBecause of these benefits, valerian essential oil may help reduce hypertension in some people.\nYlang-ylang\nResearchers have used ylang-ylang essential oil in combination with other oils to effectively lower blood pressure.\nA small study from 2013 reported that the aroma of ylang-ylang may have a sedative effect that significantly decreases blood pressure.\nSource Article from https://www.medicalnewstoday.com/articles/327226.php", "pred_label": "__label__POS", "pred_score_pos": 0.7971890568733215}
{"content": "Of all the emotions and settled thoughts which have convinced me inalterably – or at the very least persuaded me beyond hesitation – two set themselves apart. One, is the recognition that razor clams in brine are not for everyone. Two, is the recognition that certain people are crazy. These are naturally purely metaphorical. The first for example captures the peculiarly individual – and innately powerful – characteristic of each of us. The second – though admittedly not as patent – is a universal trait which springs from a lapse which any one of us might suffer. Consider those instances when sudden paranoia or frightful impalpability arise.\nThese trademarks are not world-altering but they assist to direct one’s mind. The razor clam allegory is a reminder that being a gourmand is not necessarily everyone’s avenue to discovery. It is as axiomatic to me that one should establish one’s individual tastes as it is for me to say, “\nIf you do what you like, then you’ll like what you do!” Yet this inescapable truth often struggles for air. Don’t allow yourself to be manipulated or contaminated by others whose only ambition is their personal favour. It helps in these matters to be guided by the principle that, “ The best mask for a treacherous heart is an honest face!” or that, “ Flattery is a net before another man’s feet“. The distillation is that when all the rubbish burns off, what’s left is closest to the heart of things. The process is inevitable though you can abuse its evolution by unnecessarily protracting the acceptance or pretending to be someone else.\nThe crazy code is ironically driven not by some very unchristian name-calling but rather by the need to accept the reality of others. Sometimes that reality is messy or disturbing.The easiest way for me to express this agenda is to compare it to the adage that one should believe what one sees. This caution directs us to ensure we haven’t confounded another’s meaning by imposing the wrong features. The result of such obfuscation is an avoidance of what is being communicated to us.", "pred_label": "__label__POS", "pred_score_pos": 0.7112612724304199}
{"content": "In the over six a long time of independence, India has committed itself to the task of developing its science and expertise. The announcement was made as we speak at a special assembly of the college for IMES and the Health Science and Technology (HST) program. RAND consultants have often been among the pioneers of key scientific analysis, including laptop evaluation, satellite development, army expertise, and the foundations of the Internet.AAAAAAAAAKA\nKnow-how has created employment for individuals who market their merchandise by way of the web. Advances in medical know-how have contributed immensely in extending the life span of individuals. If that’s the case, an advert-hoc wi-fi community could be created between the two computer systems by configuring both terminals to advert-hoc mode.schulen*eduhi*at\nIn response to the problem of accelerating the area’s scientific and technological capacities, the Group, through the Inter-American Committee on Science and Know-how (COMCYT), contributes to the formulation and implementation of policies and initiatives to advertise science, expertise and innovation inside the framework of the partnership for improvement.\nThe MPO cassettes can double the concentration which might be potential in rack-mount enclosures – up to 72 optic fibers in a 1U enclosure and 288 optic fibers in a 4U enclosure – making these optic fibers completely match to fulfill high density functions, similar to knowledge heart’s and storage area networks.\nScience has adequately, energetically and productively advanced, modified, civilized, enhanced and progressed human life. This science, along with biophysics, aims to deliver a better understanding of how our bodies work – from how we turn meals into vitality to how nerve impulses transmit.", "pred_label": "__label__POS", "pred_score_pos": 0.8864152431488037}
{"content": "Abstract\nThe rat Na\n+/H + exchanger isoform-2 (NHE-2) gene promoter lacks a TATA box and is very GC rich. A minimal promoter extending from bp -36 to +116 directs high-level expression of NHE-2 in mouse inner medullary collecting duct (mIMCD-3) cells. Four Sp1 consensus elements were found in this region. The introduction of mutations within these Sp1 consensus elements and DNA footprinting revealed that only two of them were utilized and are critical for basal transcriptional activation in mIMCD-3 cells. The use of Sp1, Sp3, and Sp4 antisera in electrophoretic mobility shift assays demonstrated that Sp1, Sp3, and Sp4 bound to this minimal promoter. We further analyzed the transcriptional regulation of NHE-2 by members of the Sp1 multigene family. In Drosophila SL2 cells, which lack endogenous Sp1, the minimal promoter cannot drive transcription. Introduction of Sp1 activated transcription over 100-fold, suggesting that Sp1 is critical for transcriptional regulation. However, neither Sp3 nor Sp4 was able to activate transcription in these cells. Furthermore, in mIMCD-3 cells, Sp1-mediated transcriptional activation was repressed by expression of Sp3 and Sp4. These data suggest that Sp1 is critical for the basal promoter function of rat NHE-2 and that Sp3 and Sp4 may repress transcriptional activation by competing with Sp1 for binding to core cis-elements. Keywords Drosophila SL2 cells Sodium-hydrogen exchanger Sp3 Sp4 mIMCD-3 cells ASJC Scopus subject areas Physiology Cell Biology", "pred_label": "__label__POS", "pred_score_pos": 0.8376606702804565}
{"content": "Bandura's 'reciprocal determinism' and the impact it has on learning.\nQuestion\nHow does reciprocal determinism affect learning?\nAnswer\nReciprocal determinism (Bandura, 1986) is a concept which asserts that a person’s behaviour both influences and is influenced by their personal qualities and the environment they are in. It can be depicted as a triangle, with ‘personal factors’, ‘environmental factors’ and ‘behaviour’ at each corner. This can have an impact on how effectively someone learns.\nReciprocal determinism is closely interlinked with self-efficacy (Bandura, 1997), which refers to the strength of a person’s belief in their ability to achieve goals. A learner with strong self-efficacy is confident and enthusiastic about participating in learning; they will often achieve in school and have their view of themselves validated, making them more likely to continue this behaviour. A learner with weak self-efficacy may struggle with self-doubt and be less willing to actively participate, thus contributing to their view that learning is not something they are ‘good at’ and further discouraging them from attempting to engage. They are more likely to dwell on possible failures before acting, which results in less effective outcomes, thereby continuing the cycle of reciprocal determinism.\nWhile a teacher cannot control learners’ ‘personal factors’, they can build a positive learning environment which is open and inclusive to satisfy the ‘environmental factors’ in the triangle. Supporting learners with weak self-efficacy will increase their willingness to participate and therefore help to modify their negative ‘behaviour’.\nReferences\nBandura, A. (1986). Social Foundations of Thought and Action: A Social Cognitive Theory. Englewood Cliffs, NJ: Prentice-Hall.\nBandura, A. (1997). Self-efficacy: The exercise of control. New York: Freeman.", "pred_label": "__label__POS", "pred_score_pos": 0.8768501877784729}
{"content": "Of the numerous psychotherapeutic models, I use ones that support my belief that relationships act as the primary influence in peoples’ life experiences. As your counselor, I want to be a constructive contributor in how you decide to live your life. Additionally, I am very interested in your strengths and what you already are doing that functions well for you. So often, psychotherapists (and their clients) spend too much time focusing on weaknesses and all the unfavorable outcomes that one has had in her/his life. Examining weaknesses and unfavorable outcomes on a limited basis can be helpful, but I have found that clients feel more hopeful, more competent, and experience better outcomes when we focus on what is desired rather than the undesirable. Having noted this, I do believe our society (in general) is too eager to minimize any possible undesirable experiences we might endure. So, I often promote peoples’ abilities to embrace a bit of suffering as they move towards their desired outcomes.\nOther positions that I promote or do not promote in my practice are as follows:\nI will not tell you that you need to take psychotropic medications. I will make referrals to medical and/or other professionals as seems helpful. I will not create a dependency between you and me. I will be responsive to your therapeutic concerns. I will not tell you that you have many “issues” with which you must deal. I will set an appointment with you generally within one to two weeks. I will not tell you that you have to follow a prescribed path in order to resolve your concerns. I will want you to be open and honest with me, and I know for some people, this is an evolving process. I will not promote how presumed diagnostic conditions, your history, your parents, etc., victimize you. I will promote healing and recovery. I will not tell you that you need to break up, separate, or divorce from your significant other. I will attempt to respect you and all of your facets, including, but not limited to, your race/ethnicity, culture, religiosity (or lack thereof), orientation, political affiliation, socioeconomic status, education, etc. I will not give you advice based on what I believe you “ought to do.” I will interact with you in a way that has research-based support. I will not tell you that you are sick, crazy, or insane. I will feel privileged that you decided to share a bit of your life with me. I will not “just listen” to you, as I don’t believe that “venting,” for the exclusive purpose of talking, ultimately resolves your concern(s). I will encourage you to be an active, responsible, and accountable participant in your recovery. I will not tell you that changing your thoughts is the only, or even the primary way, that change occurs. I will, with your signed permission, collaborate with others (e.g., professionals, family members, friends, etc.) to help you move towards desired outcomes. I will not ask you “why” you do anything nor will I spend a lot of time attempting to explain theoretically your experiences. I will emphasize your specific, measurable, and desired outcomes.", "pred_label": "__label__POS", "pred_score_pos": 0.8650007843971252}
{"content": "Scientists have a responsibility to share their work and findings, with the public at large. What can be difficult is creating a dialogue that allows non-colleagues to understand and comprehend such complex terminology and jargon. The GFJC has a two-prong approach to making science communication effective – public outreach and professional training.\nScience Communications Public Outreach\nWith camps for kids that introduces them to\nreal, not Fauxrensics, and free downloadable classroom resources, we can stop the CSI Effect before the students are old enough to sit in the jury box. We provide teacher training tools and materials to assist in forensic science curriculum from kindergarten to 12 thgrade. We also produce video content aimed at explaining the complex science you may see in the headlines in simple-to-understand methods. Professional Training\nWhether it’s supporting the graduate certificate in Science Communications at the FIU College of Communication, Architecture + The Arts, or creating professional development opportunities to share best practices through our Annual Forensic Science Symposium, we are here to support professional science communication. We advocate for communication between the science, legal and public silos to unite the sciences for justice.", "pred_label": "__label__POS", "pred_score_pos": 0.551476001739502}
{"content": "Federal Policies\nMany federal agencies including the Department of Education, the Centers for Medicare and Medicaid Services (CMS), the Substance Abuse and Mental Health Services Administration (SAMHSA) and the Centers for Disease Control and Prevention (CDC) are supporting the expansion of Medicaid services in schools and the creation of safe and supportive school environments. Federal agencies support this work through several mechanisms, including providing direct funding to local and state agencies, funding research and disseminating evidence, creating guidance documents, establishing learning networks, and through other technical assistance opportunities.\nFederal policies and programs can also support states and localities in building the cross-sector infrastructure needed to implement evidence-based programs and practices–including professional development and workforce solutions.\nFederal Policy Resources\nThis case study highlights Tennessee’s work to leverage the nation’s education law, the Every Student Succeeds Act (ESSA), to support the critical connection between health and learning. Tennessee’s inclusion of health and wellness in its ESSA plan and the guidance developed to support district-level implementation provide best practices and lessons learned for states striving to support student health and wellness through education policy and practice.\nKirsten Beronio, Centers for Medicare and Medicaid Services\nMelinda Hollinshead, Public Consulting Group\nThis toolkit provides information and resources to mobilize communities to expand school-based services for substance use prevention and early intervention.\nThis policy update highlights actions state education decision-makers can take to address the health-related causes of chronic absence.\n\"Presentation delivered by CMS for the Healthy Students, Promising Futures Learning Collaborative providing an overview of Medicaid reimbursement in the school setting. The presentation addresses issues including the free care policy, certified public expenditures and telehealth.\n\"\nThis webinar provides an overview of the Early and Periodic Screening, Diagnostic and Treatment Benefit (EPSDT) requirements.\nThis report outlines the opportunities for managed care to address the social determinants of health, provides examples of state-led initiatives and health plan best practices, and reviews the barriers and challenges.\nThis webinar provides an overview of the Early and Periodic Screening, Diagnostic and Treatment Benefit (EPSDT) requirements.\nThis brief for school superintendents provides an overview of how school districts can leverage Medicaid to support children's educational and health outcomes.", "pred_label": "__label__POS", "pred_score_pos": 0.6706270575523376}
{"content": "Zero Failure Management at Maximum Productivity in Safety Critical Control Room Lecture Permanent lenkehttp://hdl.handle.net/11250/2481158 Utgivelsesdato2011 MetadataVis full innførsel Sammendrag\nPredicted growth in air traffic and demand for increased safety, predictability, and efficiency impose additional demands on Air Traffic Management (ATM) systems. Different technologies are currently under development to address these demands. However, one area continues to leave significant room for improvement: productivity in the control room. This paper proposes improvement of control room productivity by applying productivity improvement methods and techniques and validating them in the context of a tower control room. We describe our approach, the challenges it poses, and our plans for validation. We believe that this approach could be useful for improving different ATM processes and could provide useful input for the development of automated tools used in control rooms.", "pred_label": "__label__POS", "pred_score_pos": 0.6622663736343384}
{"content": "PwC has committed to retaining all its office space despite the rise of home working during the pandemic.\nThe big four accountant's UK chairman, Kevin Ellis, said that while hybrid working was here to stay, he believed the office would remain a key part of working life.\n\"The pandemic has accelerated changes to working patterns, bringing things forward by three or four years. Hybrid working is here to stay, and therefore the office will remain a key part of working life.\"\n\"The future of the market for office space is difficult to predict, if anything at the moment we need more space than ever because of social distancing.\n\"From the messages I get from our people I know they really value having the option to use an office, whether for a personal or a business need.\n\"In the longer term, it will be important to continue to ensure offices offer something more than people can get at home, whether its working together, innovating or learning. I am sure I'm not alone in wanting this to be the case.\"\nAlmost double the number of Britons travelled to work in early October compared with the height of lockdown in May, according to official data.\nSome companies have warned productivity has fallen during the pandemic, blaming working from home as a key factor.\nHowever, take-up of new office space has fallen sharply since the start of the pandemic, as government statistics show nearly three in 10 workers still opted to stay home last week. The figures represent the highest proportion of employees staying at home since July.\nAccording to British Land, only 18pc of workers had returned to their London offices by mid-September compared to pre-crisis levels. This is despite office occupancy of tenants being at 95pc, leading to concerns that tenancies will plummet once leases begin to end.\nNicholas Hyett of Hargreaves Landsown seriously questioned earlier this month whether current rental rates can be maintained if customers staff don't return widely.", "pred_label": "__label__POS", "pred_score_pos": 0.8477298617362976}
{"content": "Immunization Immunization is one of the most important tools to keep children alive and healthy. The challenge\nTotal immunization coverage in Moldova is relatively high. Based on data from the MICS 2012 survey, 89% of the children 15-26 months of age received all recommended vaccines.\nHowever, Moldova is facing an alarming trend of declining vaccine coverage. Today, with the existing gaps in coverage, the country is at risk of failing to reach the target vaccination rate. Most of those who refuse to immunize their children are middle class, well educated parents. However, the immunization rated are also dropping among other categories, including the vulnerable ones. The extent to which the Roma use healthcare services is determined by access, lifestyle, migration, and lack of knowledge in assessing health risks.\nThe solution\nUNICEF supports immunization programmes in over 100 countries, including Moldova.\nImproving access to vaccines, facilitating comprehensive vaccination programmes, and countering vaccine hesitancy are among our priorities. Joint efforts in implementing the National Immunization Programme led to the protection of children from vaccine-preventable diseases. UNICEF Moldova, along with WHO and other partners, also strengthened the country’s capacity to introduce new vaccines into the immunization schedule, increasing children’s protection from additional infectious diseases.\nCold chain equipment is vital to ensuring vaccine quality, safety and efficacy. Cold rooms, cold boxes, vaccine carriers, fridges, freezers, and thermometers were an in Moldova, including Transnistrian region with UNICEF support and EU funding.", "pred_label": "__label__POS", "pred_score_pos": 0.9403938055038452}
{"content": "Claim arising out of rape in psychiatric award is upheld on appeal; recipient rights \"decision\" was not trustworthy or admissible\nMary Sloan was involuntarily admitted to Chelsea Community Hospital after a suicide attempt. During her stay, a male patient entered her room and raped her. The male patient had earlier been escorted from her room by staff after he entered uninvited. Sloan sued the Hospital, arguing that it had improperly failed to protect her from the potential rapist. She presented the testimony of two psychiatric nurses with a combined 50+ years of experience: they testified that the nursing staff of a psychiatric unit owes a duty to vigilantly protect patients from this type of assault and that Chelsea's staff had violated the standard of care. The jury awarded Sloan $100,000.00 in non-economic damages and $50,000.00 in economic damages. Chelsea appealed.\nChelsea argued that Sloan had not met her burden of proving negligence because her experts had suggested that when an event of this type occurs, the Hospital is always responsible and negligent. The Court rejected this argument, finding it a question of fact, properly resolved by the jury, with regard to the staff's negligence.\nThe Hospital also argued that it owed no duty to protect Sloan from the criminal behavior of a third person. The appellate judges noted that an exception to this rule applies when a \"special relationship\" exists between the victim and a defendant. Given this exception and the hospital's failure to properly raise this issue on appeal, the Court did not grant the hospital relief.\nA Community Mental Health Recipient Rights decision, upheld on administrative appeal, concluded that the incident did not arise out of neglect. The Hospital argued that this administrative \"decision\" should have precluded Sloan from suing and that it constituted a binding judgment of lack of fault by Chelsea. The Court noted that this report by the CMH recipient rights officer was not adversarial or judicial in nature, and therefore not the type of decision that would preclude Sloan from her \"day in court.\"\nThe appellate judges also noted that the Report, itself, lacked the type of trustworthiness that would allow it to be admitted for the jury's consideration. The Michigan Supreme Court has previously held that reports generated under circumstances of \"highly probably civil and criminal litigation\" lack the trustworthiness required for admissibility under the Michigan Rules of Evidence and hearsay.", "pred_label": "__label__POS", "pred_score_pos": 0.6180996894836426}
{"content": "This descriptive survey study aimed to explore how nursing students perceive spirituality/spiritual care and investigate the variables acting on their perception. Data were collected using the Spirituality and Spiritual Care Rating Scale with 500 students from the Faculty of Nursing. The students' median score regarding their perception of spirituality and spiritual care indicates a \"conceptual confusion\" related with these concepts. Female students have higher scale scores than male students (z = 2.19, p < 0.05). Students' awareness of spirituality and related concepts, and their acquisition of spiritual care skills will allow them to provide spiritual care after graduation.", "pred_label": "__label__POS", "pred_score_pos": 0.6957380771636963}
{"content": "The most flexible program for undergraduate English majors, the\nLiterary Studies program starts with a foundational sequence of three core requirements that focus on three core principles of literary study: skills for close reading, because literature is not self-evident but interpreted; skills for theoretical analysis, because there are principles governing how we interpret and how the text-reader and text-author relationships work; and skills for understanding literary historyand the methods used to apprehend the cultural context of earlier periods, because literature is situated within a specific time and place, develops in relation to socio-cultural events, and access to texts from earlier periods is always mediated.\nThe next stage encourages students to distribute their courses across a range of diverse perspectives, historical periods, and genre. In addition, students can choose from several options for their “capstone” to the major, including capstone courses and internships. Meanwhile, students can use 12 or more elective credits to explore the wide range of subjects and topics offered in the department, from creative writing to film to cultural studies to linguistics. This innovative, flexible curriculum allows students to explore their interests while providing experience in a diverse array of critical practices. Some students prefer to use their elective credits to pursue a topic of interest in more depth, while others prefer to sample a variety of offerings from many fields.\nGraduates of the literary studies concentration are ready for entry-level jobs in any field, industry, or profession searching for people with sharp analytical and writing skills.\nContact\nAndrew Murray, Undergraduate English Advisor: murraya8@msu.edu\nKristin Mahoney, Director of Literary Studies: mahone95@msu.edu David Stowe, Associate Chair of Undergraduate Studies in English: stowed@msu.edu", "pred_label": "__label__POS", "pred_score_pos": 0.8732564449310303}
{"content": "Condominium and Cooperative Law in Massachusetts\nCooperatives and condominiums are instances of \"common interest\" communities.\nThese are communities in which each resident rents or owns a residential unit. The residential units are part of a larger building, or complex of buildings, which are owned by another entity, such as a corporation or association. The residents are accountable for the upkeep of common areas, such as lawns and walkways. Rather than personally tending to these things, residents usually pay a fee that covers these necessities.\nMerely viewing one of these communities from the outside (or inside) will not let you discern whether it's a cooperative or condominium community.\nThis is because there are no physical characteristics that can precisely distinguish one from the other. The major difference lies in the legal ownership arrangement. In a condominium community, the units are actually owned by the residents. The residents also collectively own the common areas, holding joint title to it. In a cooperative community, the buildings and land which make up the houses are owned by a single entity, and the individual units are often rented rather than owned by the residents.\nLaws and Regulations Concerning Common Interest Communities in Nantucket, Massachusetts\nNumerous Nantucket, Massachusetts laws affect common-interest communities. However, almost all of these laws govern real estate more generally, and there are very few laws written particularly for common interest communities. Such generally-applicable laws include zoning regulations, contracts, and the relations between landlords and tenants.\nGenerally, the rules established by the owner of the property, or the entity tasked with managing it, are going to have much more of a day-to-day effect on your life than any state laws governing these types of communities.\nThe land on which these communities sit is private property, so the owners have significant leeway when it comes to setting rules regarding what tenants can and can't do on the property. These rules generally govern things like noise levels, cleanliness, long-term guests, and pets. They are often designed with the goal of balancing residents' rights to a clean and quiet neighborhood, with their individual autonomy.\nThe enforceability of some of these rules may depend on Nantucket, Massachusetts's laws controlling relations between landlords and tenants.\nCan a Nantucket, Massachusetts Attorney Help?\nIf you are in a dispute with your homeowners' association, a neighbor, or your landlord in Nantucket, Massachusetts, a reputable real estate lawyer may prove extremely helpful, if the dispute cannot be otherwise resolved.", "pred_label": "__label__POS", "pred_score_pos": 0.7317472696304321}
{"content": "Condominium and Cooperative Law in Wyoming\nCooperative and condominium communities are examples of a class of housing developments identified as \"common interest communities.\"\nThey are communities where each individual or family resident rents or owns an unit which is part of a larger building, containing other, similar, residential units. The residents are accountable responsible for the maintenance of the common areas of their living areas, such as gardens, walkways, lawns, and swimming pools. They typically meet this responsibility by paying a monthly fee to support this maintenance.\nJust looking at the outside (or inside, for that matter) of a condo or cooperative community, you likely can't tell which it is.\nThis is because there are no defining physical characteristics which are distinct to one type of cooperative community, but not the other. The significant differences aren't embodied in physical characteristics, but in the legal ownership arrangement governing the communities: in a condominium community, the residents own the units they live in. In a cooperative community, the units are rented.\nLaws and Regulations Concerning Common Interest Communities in Laramie, Wyoming\nLaramie, Wyoming likely has numerous laws and regulations concerning common interest communities. Nonetheless, these are mostly limited to the laws and regulations (zoning, land use, etc.) that concern all real estate owners.\nIn general, the procedures of the landowner or management board will have a much greater impact on the daily lives and conduct of residents than any state or local laws controlling condominiums or cooperatives.\nThe land that common interest communities occupy is typically private property. Therefore, the owners of the property are free to make certain rules governing what is and isn't allowed on it. A good manager or owner will typically make every effort to strike a balance between residents' freedom to do what they want in their homes, and the rights of their neighbors to a safe, clean, and reasonably quiet living space.\nSome rules set by property owners or managers may not be enforceable, however. For instance, in Laramie, Wyoming, any rule which purports to exclude residents based on race, color, national origin, or religion will not be legitimate. There are likely some others, as well.\nCan a Laramie, Wyoming Attorney Help?\nIf you are involved in an argument with your neighbor, in conflict with a zoning regulation, or in a dispute with your landlord, a reliable Laramie, Wyoming real estate attorney can help you prevail.", "pred_label": "__label__POS", "pred_score_pos": 0.5420846939086914}
{"content": "A business practice where a company owns its own supply chain. For example, owning the farms where hemp is grown, the barns where it’s stored, and the labs where it’s processed. This means that a vertically integrated company can ensure tighter quality control and maintain their core values and practices across all parts of the production process.\nVertical integration\nTeam Omni", "pred_label": "__label__POS", "pred_score_pos": 0.9924541115760803}
{"content": "Self-Ligating Braces\nSelf-ligating braces are similar to traditional braces, but they do not need elastics. This means less friction on the tooth, easier cleaning, less visibility, and fewer appointments to get your braces adjusted. They can use metal, ceramic, or clear brackets. A specialized clip helps the archwire guide the teeth.\nClear (Ceramic) Braces\nThese braces have clear or ceramic brackets. The clear brackets allow the tooth to show through, while the ceramic brackets mimic the color of the teeth, letting them blend in. These may be visually less prominent, but they have some drawbacks. Both can become discolored without diligent care, and ceramic braces can become chipped or broken.\nClear Aligners\nAligners are invisible when worn, removable, and more comfortable than braces since they sit flush against the teeth. Since they can be removed for a few hours each day, they make eating, drinking, brushing, and flossing easier. In most cases, they work faster than braces, and patients require fewer office visits.\nTraditional Metal Braces\nThese are the braces you picture when you think about orthodontic treatment. Compared to versions of the past, they are smaller, lighter, and more effective. If you want to be creative, you can opt for colored elastics or even specially shaped brackets.", "pred_label": "__label__POS", "pred_score_pos": 0.5915042161941528}
{"content": "Vaccination and 30-day mortality risk in children, adolescents, and young adults Overview Research View All Overview abstract OBJECTIVE: This study evaluates the potential association of vaccination and death in the Vaccine Safety Datalink (VSD). METHODS: The study cohort included individuals ages 9 to 26 years with deaths between January 1, 2005, and December 31, 2011. We implemented a case-centered method to estimate a relative risk (RR) for death in days 0 to 30 after vaccination. Deaths due to external causes (accidents, homicides, and suicides) were excluded from the primary analysis. In a secondary analysis, we included all deaths regardless of cause. A team of physicians reviewed available medical records and coroner's reports to confirm cause of death and assess the causal relationship between death and vaccination. ESULTS: Of the 1100 deaths identified during the study period, 76 (7%) occurred 0 to 30 days after vaccination. The relative risks for deaths after any vaccination and influenza vaccination were significantly lower for deaths due to nonexternal causes (RR 0.57, 95% confidence interval [CI] 0.38-0.83, and RR 0.44, 95% CI 0.24-0.80, respectively) and deaths due to all causes (RR 0.72, 95% CI 0.56-0.91, and RR 0.44, 95% CI 0.28-0.65). No other individual vaccines were significantly associated with death. Among deaths reviewed, 1 cause of death was unknown, 25 deaths were due to nonexternal causes, and 34 deaths were due to external causes. The causality assessment found no evidence of a causal association between vaccination and death. CONCLUSIONS: Risk of death was not increased during the 30 days after vaccination, and no deaths were found to be causally associated with vaccination. Link to Article publication date published in", "pred_label": "__label__POS", "pred_score_pos": 0.9819486737251282}
{"content": "2018 was a record-breaking year for JAMK’s RDI activities, marking an increase of 19% compared to the previous year. External funding for RDI activities amounted to\n€7.9M (€6.6M in 2017), marking a growth of approximately €1.3M compared to the previous year. As expected, the total volume kept increasing, reaching €11.0M (€9.4M in 2017). The RDI activities were more extensive than ever as international operations were strengthened and the operational volume remained at the target level throughout the entire year.\nThe RDI efforts developed with a focus on the strengths specified by JAMK’s strategy, including education and business expertise, bioeconomy, applied cybersecurity, multidisciplinary rehabilitation, and automation and robotics as an emerging field. The effectiveness of RDI activities was a particular area of effort. Other development areas selected based on an external evaluation of the RDI activities were also moved actively forward, especially those related to applied research and communications. The EduFutura co-operation with key partners, the University of Jyväskylä and the municipal education consortium was diverse. JAMK experts were actively involved in the development of the Kangas, Nova (new hospital) and Hippos areas.", "pred_label": "__label__POS", "pred_score_pos": 0.9990109801292419}
{"content": "Abstract\nBackgroundCommunication failures involving test results contribute to issues of patient harm and sentinel events. This article aims to synthesise review evidence, practice insights and patient perspectives addressing problems encountered in the communication of diagnostic test results.MethodsThe rapid review identified ten systematic reviews and four narrative reviews. Five practitioner interviews identified insights into interventions and implementation, and a citizen panel with 15 participants explored the patient viewpoint.ResultsThe rapid review provided support for the role of technology to ensure effective communication; behavioural interventions such as audit and feedback could be effective in changing clinician behaviour; and point-of-care tests (bedside testing) eliminate the communication breakdown problem altogether. The practice interviews highlighted transparency, and clarifying the lines of responsibility as central to improving test result communication. Enabling better information sharing, implementing adequate planning and utilising technology were also identified in the practice interviews as viable strategies to improve test result communication. The citizen panel highlighted technology as critical to improving communication of test results to both health professionals and patients. Patients also highlighted the importance of having different ways of accessing test results, which is particularly pertinent when ensuring suitability for vulnerable populations.ConclusionsThis paper draws together multiple perspectives on the problem of failures in diagnostic test results communication to inform appropriate interventions. Across the three studies, technology was identified as the most feasible option for closing the loop on test result communication. However, the importance of clear, consistent communication and more streamlined processes were also key elements that emerged.Review registrationThe protocol for the rapid review was registered with PROSPERO CRD42018093316.", "pred_label": "__label__POS", "pred_score_pos": 0.9457602500915527}
{"content": "For a long time, the cure for diabetes type 1 and type 2 has relied on agonizing insulin shots for patients or insulin infusion via mechanical pumps. Regarding this, experts have been creating artificial pancreatic beta cells with the he…\nIn this report, LP Information covers the present scenario (with the base year being 2017) and the growth prospects of global Neuroprotective Products market for 2018-2023.\nNeuroprotective Products consist of medications that can be used to protect or preserve the neuronal cells of the brain from degeneration, stress, and injury, which can impair cognitive functions.\nOver the next five years, LPI(LP Information) projects that Neuroprotective Products will register a xx% CAGR in terms of revenue, reach US$ xx million by 2023, from US$ xx million in 2017.\nThis report presents a comprehensive overview, market shares, and growth opportunities of Neuroprotective Products market by product type, application, key manufacturers and key regions.\nTo calculate the market size, LP Information considers value and volume generated from the sales of the following segments:\nSegmentation by product type:\n- Cholinesterase inhibitors\n- NMDA receptor antagonists\n- Others\nSegmentation by application:\n- Alzheimer's disease\n- Multiple sclerosis\n- Others\nThis report also splits the market by region:\n- Americas\n- - United States\n- - Canada\n- - Mexico\n- - Brazil\n- APAC\n- - China\n- - Japan\n- - Korea\n- - Southeast Asia\n- - India\n- - Australia\n- Europe\n- - Germany\n- - France\n- - UK\n- - Italy\n- - Russia\n- - Spain\n- Middle East & Africa\n- - Egypt\n- - South Africa\n- - Israel\n- - Turkey\n- - GCC Countries\nThe report also presents the market competition landscape and a corresponding detailed analysis of the major vendor/manufacturers in the market. The key manufacturers covered in this report:\n- Genervon Biopharmaceuticals (Canada)\n- NeuroVive Pharmaceutical (Sweden)\n- Ceregene (USA)\n- BHRPharma (Thailand)\n- Neuren Pharmaceuticals (Australia)\n- Allon therapeutics (Canada)\n- Bionure Inc. (USA)\n- ...\nIn addition, this report discusses the key drivers influencing market growth, opportunities, the challenges and the risks faced by key manufacturers and the market as a whole. It also analyzes key emerging trends and their impact on present and future development.\nResearch objectives\n- To study and analyze the global Neuroprotective Products consumption (value & volume) by key regions/countries, product type and application, history data from 2013 to 2017, and forecast to 2023.\n- To understand the structure of Neuroprotective Products market by identifying its various subsegments.\n- Focuses on the key global Neuroprotective Products manufacturers, to define, describe and analyze the sales volume, value, market share, market competition landscape, SWOT analysis and development plans in next few years.\n- To analyze the Neuroprotective Products with respect to individual growth trends, future prospects, and their contribution to the total market.\n- To share detailed information about the key factors influencing the growth of the market (growth potential, opportunities, drivers, industry-specific challenges and risks).\n- To project the consumption of Neuroprotective Products submarkets, with respect to key regions (along with their respective key countries).\n- To analyze competitive developments such as expansions, agreements, new product launches, and acquisitions in the market.\n- To strategically profile the key players and comprehensively analyze their growth strategies.", "pred_label": "__label__POS", "pred_score_pos": 0.7226858139038086}
{"content": "Johannesburg, 14 October 2020 - As Governments across the world implemented a range of measures to slow the spread of COVID-19, Chartered Accountants Worldwide members were there to provide support and resources.\nTheir work involved:\nDirect contact at the highest levels with Governments to make recommendations and influence policy from a financial and business perspective. Seeking and providing clarity on business support initiatives designed to counter the impact of COVID-19. Reaching significant audiences of members, practice firms and other stakeholders through webinars, online guides, and social media to guide them through new legislation and business support.\nChartered Accountants Worldwide wanted to discover how its member institutes in Australia and New Zealand, Bangladesh, England, Scotland and Wales, Indonesia, Ireland, Pakistan, Singapore, South Africa, Sri Lanka and India had been working with their Governments to help them strategically plan their recovery. We published the findings on Charteredaccountantsworldwide.com.\nIn that article, we also highlighted how Governments are now experiencing higher levels of trust, as measured by the Edelman Trust Barometer. By taking swift action to support and engage with Governments, Chartered Accountants member institutes are helping to build and reinforce that trust, by showing leadership and influence, while highlighting their value to members and to the wider community.\nIn this article, we focus on the impact CAW member institutes made across their economies, the businesses in their countries, and their members.\nAustralia and New Zealand: CA ANZ\nIn Australia, CA ANZ’s COVID-19-related advocacy achieved a media reach of 4.4 million by the first week of May. And across Australia and New Zealand, their COVID Sharing Knowledge sessions for members achieved 30,000 registrations by the end of May.\nCA ANZ advocated with the Federal Government for recognition of accounting as an ‘essential service’, and was part of a group of accountants and financial planners that successfully applied to Australia’s Securities and Investments Commission for regulatory relief. This resulted in more Australians getting the help they needed to understand the Federal Government’s COVID-19 economic packages, including early access to their superannuation.\nBangladesh: ICAB\nThe Bangladesh Government considered several recommendations from ICAB. This included supporting business and the economic recovery in the national budget and fiscal policy whilst another focused directly and indirectly on widening the tax net for revenue generation with an aim to achieve a higher tax GDP ratio. ICAB also proposed allocating sufficient budget to create a social safety net for low-income groups.\nAs part of serving society at large with useful information and guidance, ICAB arranged several seminars, press conferences and discussions with members and relevant stakeholders including key regulators and Government.\nIreland: Chartered Accountants Ireland\nA key initiative of Chartered Accountants Ireland was the development and publication of “The Next Financial Year: Making Irish Business More Competitive.” This multi-disciplinary position paper considered how the Government in ROI and NI can simplify processes and remove red tape to support business recovery and expansion.\nMany measures proposed by the policy have been adopted by both the Irish and UK Governments. Subsequently, Government Ministers and HMRC have acknowledged the important contributions Chartered Accountants Ireland have played during this COVID-19 pandemic.\nIndonesia: IAI\nInIndonesia, Micro, Small and Medium Enterprises (MSMEs) are among the hardest hit by the COVID-19 crisis, with 47% expected to experience significant disruption. Under the ‘IAI for Society’ banner, IAI actively equipped practising Chartered Accountants in accounting services firms with the latest know-how, focusing on building resilience and how to overcome uncertainties connected to the pandemic.\nIAI also highlighted the role of Chartered Accountants as trusted advisors, especially those in the public sector, given their important role in overseeing the refocusing and realising of the state’s budget into COVID-19 initiatives.\nPakistan: Institute of Chartered Accountants Pakistan\nICAP held webinars to create awareness, give insights and educate participants on current issues including organisational resilience, business transformation, and the impact of COVID-19. These were extremely well received, reaching audiences of over 95,000.\nTo support members during the pandemic, ICAP made all of its study texts available online free of charge and arranged courier delivery of books to more than 3,000 students.\nSingapore: ISCA\nISCA published technical guidance on audit and financial reporting issues arising from the pandemic. They held a series of advisory sessions for accounting practices to help them ensure business continuity safely during COVID-19. Together with Government agency, ISCA also co-organised a Virtual Career’s Fair for Accounting and Finance Professionals, which attracted more than 11,000 visitors in two weeks.\nWith the pace of digital transformation accelerating amid the pandemic, ISCA launched the SMP Programme with the support of Enterprise Singapore, a Government agency. This initiative aims to drive digitalisation, upskilling and internationalisation of Singapore’s SMPs.\nSouth Africa: SAICA\nSince South Africa’s lockdown took effect on 27 March, SAICA made 11 submissions on issues ranging from tax policy and compliance to relief bills and the national budget, at the request from regulators and standards setters. It also presented to the national parliament on the supplementary budget and held webinars to explain the Unemployment Insurance Fund process to its members.\nSAICA served on the Ministerial Paying Tax Workgroup and the Labour Workgroup. Other advocacy efforts included submissions to Business for South Africa (B4SA) for relief negotiations and Unemployment Insurance Fund (UIF) labour relief, drafts of two tax disaster relief bills, regulations on “essential and permitted services”, and on the UIF Temporary Employee/Employer Relief Scheme (TERS) benefit regulations.\nSri Lanka: CA Sri Lanka\nCA Sri Lanka took several initiatives to enhance the skill sets of its 6000 members. It contacted local chambers and the Government, offering support and services to restructure and resuscitate the economy.\nIt was also involved in the launch of a task force to identify economic segments where its members could offer help, including the SME sector, which accounts for over a million entities contributing over 50% of national GDP.\nIndia: ICAI\nSeeking to support its Government through these troublesome times, the ICAI has played a crucial role in creating awareness and implementing relief packages. Using its 1 million strong student and member community, the ICAI rallied financial donations to the Relief in Emergency Situations fund, in addition to continuing its influential participation in India’s efforts to create Atmanirbhar Bharat (a Self-Reliant India).\nTo keep its members up to date and maintain a minimalistic impact to small and medium practitioners, ICAI offered free support to the professional community. Using initiatives such as the DLH (Digital Learning Hub), they were able to grant free access to structured CPE hours, provide various webinars and virtual certificate courses.\nUK: ICAEW (England and Wales)\nICAEW’s collaboration with the UK Government focused on fine-tuning the Government’s COVID initiatives for businesses and looking at how companies can reopen from lockdown while protecting the safety of staff at work and adapting physical workplaces for social distancing.\nAs well as working with the Government, ICAEW continued to engage with Opposition front bench spokespersons and key stakeholders on UK Parliamentary Committees.\nUK: ICAS\nBoth UK and Scottish Governments had welcomed, listened and responded to a number of the matters that ICAS raised, particularly in relation to the fine-tuning of the job retention and income support schemes.\nTo help the Scottish Government to strategically plan its approach to the recovery, ICAS actively encouraged Chartered Accountants in key organisations across all sectors to ensure that their organisations responded to the proposed plan. ICAS also submitted its own response focusing on funding, accountability and scrutiny, sustainability and taxation.", "pred_label": "__label__POS", "pred_score_pos": 0.813205897808075}
{"content": "Buying groups are under attack from competition authorities across Europe. Joint buying arrangements are aimed at strengthening participating companies' bargaining power towards their trading partners, usually resulting in lower prices or better quality for consumers. However, these buying arrangements must stay on the right side of the line between legitimate cooperation and anticompetitive collusion. Competition concerns may arise if the participating companies have a significant degree of market power or coordinate their conduct.\nThe European Commission and various national competition authorities are currently investigating several buying groups, as well as a number of potential buying cartels. Companies are well-advised to invite their procurement teams to their competition compliance training and to double-check whether their buying arrangements stay on the right side of the line.\nCompetition investigations into buying groups\nThe European Commission recently raided the premises of two French retail groups (Casino and Intermarché) as part of its investigation into whether these groups went beyond the purpose of their purchasing alliance and possibly colluded on consumer pricing and store networks. According to the Commission, the growing number of alliances in the food retail sector, alongside changes in alliance partners, have increased the risk of collusion.\nThe Commission's competition concerns about buying alliances seem to be shared by more European competition authorities. The Belgian competition authority is currently investigating a purchasing partnership concluded last year between Carrefour and Provera. According to a newspaper, the investigation was opened after suppliers complained about being forced to grant discounts to the purchasing alliance without any consideration. Similarly, the Czech competition authority has imposed a fine of CZK 164 million (approx. EUR 6.4 million) on the Rewe retail chains and Rewe Buying Group for abusing their significant market power by squeezing bonuses out of their suppliers. The German competition authority prevented a planned merger between purchasing cooperations in the furniture sector for fear of the new entity becoming too powerful, to the detriment of consumers and suppliers. The French competition authority is taking a closer look at the competitive impact of various supermarket purchasing alliances on the relevant markets for consumers and suppliers, while the Norwegian competition authority recently conducted a dawn raid in the grocery sector following its inquiry into purchasing conditions for grocery chains.\nBuying cartels\nBesides intensified scrutiny of joint buying arrangements, the number of investigations into buying cartels also appears to be on the increase. The Commission's investigations into potential anticompetitive conduct related to the purchasing of the chemical products styrene monomer and ethylene are still ongoing.\nThe Dutch competition authority (the ACM) has conducted dawn raids at various traders to investigate their involvement in a potential purchasing cartel in the agricultural sector. The ACM suspects the traders of coordinating the prices paid to farmers for their agricultural products. The investigation is part of a wider inquiry into potential anti-competitive conduct in the agricultural sector.\nThe German competition authority imposed fines totalling EUR 100 million on car manufacturers BMW, Daimler and Volkswagen for their alleged involvement in a steel purchasing cartel. According to the German competition authority, the car manufacturers regularly met with steel producers, forging companies and large systems suppliers to agree on uniform scrap and alloy surcharges. These surcharges represent a significant part of the long steel purchase prices. In contrast to more 'traditional' buying cartels, in this case both the purchasers and the suppliers were involved in the purchase price-fixing. However, the German competition authority opted to terminate its investigations against the suppliers\n\"for discretionary reasons\".\nFines imposed for participating in a buying cartel can be substantial, as underlined by the General Court's recent rulings in the alleged car battery recycling cartel. The General Court reduced the fine imposed on one of the cartel participants, because the Commission, inter alia, failed to prove that the company had participated in the cartel for its entire duration. However, the Commission's novel fining approach in regard of the buying cartel was upheld. The Commission had departed from its general fining methodology and took account of the value of purchases, instead of sales, to determine the fine level. Since purchases are normally lower than sales in value terms, the Commission applied a 10% increase of the fine amount to ensure a sufficient deterrent effect. According to the General Court, the Commission's explanation was sufficiently substantiated for it to deviate from its general fining methodology [see our June 2019 Newsletter]. It therefore maintained the 10% fine increase.\nGiven these recent developments, companies are well-advised to double-check whether their buying arrangements stay on the right side of the line between legitimate cooperation and anticompetitive collusion. In addition, they should make sure to invite their procurement teams to their competition compliance training.\nThis article was published in the Competition Newsletter of December 2019. Other articles in this newsletter:", "pred_label": "__label__POS", "pred_score_pos": 0.7319386005401611}
{"content": "Bats are excellent models for studying the molecular basis of sensory adaptation. In Chiroptera, a sensory trade-off has been proposed between the visual and auditory systems, though the extent of this association has yet to be fully examined. To investigate whether variation in visual performance is associated with echolocation, we experimentally assayed the dim-light visual pigment rhodopsin from bat species with differing echolocation abilities. While spectral tuning properties were similar among bats, we found that the rate of decay of their light-activated state was significantly slower in a nonecholocating bat relative to species that use distinct echolocation strategies, consistent with a sensory trade-off hypothesis. We also found that these rates of decay were remarkably slower compared with those of other mammals, likely indicating an adaptation to dim light. To examine whether functional changes in rhodopsin are associated with shifts in selection intensity upon bat Rh1 sequences, we implemented selection analyses using codon-based likelihood clade models. While no shifts in selection were identified in response to diverse echolocation abilities of bats, we detected a significant increase in the intensity of evolutionary constraint accompanying the diversification of Chiroptera. Taken together, this suggests that substitutions that modulate the stability of the light-activated rhodopsin state were likely maintained through intensified constraint after bats diversified, being finely tuned in response to novel sensory specializations. Our study demonstrates the power of combining experimental and computational approaches for investigating functional mechanisms underlying the evolution of complex sensory adaptations.\nSource link", "pred_label": "__label__POS", "pred_score_pos": 0.9875637292861938}
{"content": "Just as a person plans for all of life's other major events, including weddings, relocations, and new jobs, one should also take steps to plan their funeral. However, death can be a difficult and uncomfortable topic to discuss, so bringing up this topic with a loved one requires care and consideration. To ensure they’re open to a conversation about funeral pre-planning, follow these steps.\nHow to Discuss Funeral Pre-Planning With a Loved One 1. Describe Your Own Plans\nEase into the conversation by bringing up your wishes for your own funeral. This way, you can more smoothly transition to asking your loved one about their plans. If they haven't considered funeral pre-planning, sharing your preferences may inspire them to start thinking about what they'd like. By introducing your wishes first, you're also inviting them into the conversation, rather than diving into the topic out of the blue.\n2. Discuss Benefits\nAs your loved one gets more comfortable talking about pre-planning, inform them of the benefits of this option. Let them know that pre-planning takes a considerable emotional and financial burden off family members, and it's often seen as a final gift from them to those they care about. Also, stress that pre-planning will ensure their preferences are honored and that they can customize the service in any way they'd like, with favorite flowers, songs, readings, or other personal touches.\n3. Take It Slow\nThis can be a big subject to digest all at once, so don't expect your loved one to commit by the end of the conversation. Keep the talk as light and casual as possible, and don't dwell on it if it's causing pain or distress. Let them know you'd like to keep the lines of communication open and that you're there if they want to continue sharing thoughts or ideas.\nWhen you or a loved one is ready for funeral pre-planning, trust DiPonzio Funeral Home in Rochester, NY. Since 1931, they’ve been serving families throughout the Monroe County area, offering funeral and memorial services, burials, and cremations that are all customized to meet your exact needs and preferences. To schedule a consultation, call (585) 429-6700. To learn more about how they can help with pre-planning, visit their website.", "pred_label": "__label__POS", "pred_score_pos": 0.5747042298316956}
{"content": "Abstract\nMyometrial contraction is a central feature of labor. Although a link between infection and preterm labor is widely accepted, surprisingly little is known about the mechanisms coupling infection-induced inflammation to myocyte contractile machinery. This study explores the myocyte response to pathogen-derived ligands in vitro. The pregnant human myometrial cell line PHM1-41 and primary cultured uterine myocytes responded to Toll-like receptor (TLR) ligands, including the bacterial wall component LPS, which at 100 ng/ml increased contraction of cells embedded within collagen gels over 72 h compared to PBS. LPS-treated myocytes secreted inflammatory mediators, including prostaglandin F2α, the cytokines TNF-α and IL-6, and a range of chemokines. The contractile response to LPS required TLR4 signaling and was independent of prostaglandin synthesis. Neutralizing TNF-α had no effect on LPS-mediated contraction; however, the Rho-associated protein kinase (ROCK) inhibitors Y-27632 (10 μM) and GSK-269962 (50 nM) both abrogated the contractile response. The finding of LPS-mediated contraction was supported by a 1.38 ± 0.072-fold (mean±SE) increase in myosin light-chain phosphorylation 48 h post-treatment, assessed by in-cell Western blot analysis. Together, these data suggest that, in addition to modulating the local inflammatory environment, pathogen-derived ligands may directly promote myometrial contractility via Rho/ROCK signaling, thus contributing to preterm labor-mediated preterm birth.\nKeywords Amides/pharmacology Blotting, Western Cell Line Cells, Cultured Female Humans Imidazoles/pharmacology Infant, Newborn Lipopolysaccharides/pharmacology Muscle Cells/cytology Muscle Contraction/drug effects Oxadiazoles/pharmacology Pregnancy Pyridines/pharmacology Reverse Transcriptase Polymerase Chain Reaction Signal Transduction/drug effects Uterine Contraction/drug effects Uterus/cytology", "pred_label": "__label__POS", "pred_score_pos": 0.5095828175544739}
{"content": "In 2005, Brian and Kim Hutton were navigating uncharted territory with their 2½-year-old child. Assigned female at birth, she began stating that she was a boy. Confused and afraid, they weren’t able to share this information with family or close friends. The feelings of isolation were overwhelming. Kim searched the internet looking to connect with other families on this journey without success.\nAfter years of struggling to connect and without local experienced professional resources, they met the Copeland family in 2009 who were raising a teenager who had lived a very similar experience. Kim immediately began urging Laurie to partner with her to form a support group so that no other family had to struggle in the same way.\nIn 2011, Kim secured a rental contract with the St. Louis Ethical Society to use their facility for monthly meetings. Laurie joined her effort, and they invited six families. With a simple, static website, the group began to grow. Families shared experienced medical and therapeutic resources as well as books and videos.\nRealizing that credibility and legitimacy would be hard-won in 2012, Kim reached out to St. Louis Children’s Hospital, one of the top ten children’s hospitals in the United States, and requested meeting space within their facility. They granted her request, and in 2015 TransParent was awarded community partner status.\nIn 2013 TransParent invested in a website that allowed them to organize local professional resources like pediatricians, endocrinologists, therapists, and surgeons as well as transgender-friendly schools, news stories, and events. Another significant milestone occurred in 2014 when TransParent launched the Gender Independent Kids Club for children aged 5 to 12, also in the St. Louis Children’s Hospital complex. Recently the age limit was raised to 17.\nToday TransParent is a 501c3 not-for-profit organization with sixteen chapters in nine states. Our mission is to normalize this naturally-occurring human experience and to empower children to live authentically.", "pred_label": "__label__POS", "pred_score_pos": 0.9143720269203186}
{"content": "The possessions you move into a rental house or apartment are precious to you. Still, property risks threaten here as in other homes, including the risk of theft. However, you can work with your landlord and on your own time to keep these theft risks low. A well-rounded\nrenters insurance policy can also help you protect yourself. Here's what to think about when making your rental home safer. Before Moving In\nRenting a home or apartment is just as safe as owning one, in most cases. However, renters are not the owners of the homes they live in. They might not know all the safety resources they have available on the property.\nAs you prepare to sign your lease and move in, remember:\nRequest that your landlord change the locks throughout the property. Don't forget to change locks on closets, gates, windows cellars or crawl spaces. Only you and your landlord should be able to access the property.\nAsk if the home contains a camera or alarm system. Reset the passwords on these devices upon moving in. Have the landlord teach you how to operate the systems.\nIf you notice potential hazards - like rusted hinges or misaligned door frames - then tell your landlord. If something doesn't work correctly, that increases the risk of a thief breaking in.\nSee if you have permission to install permanent safety devices. These might include doorbell cameras, motion-activated lights or key-code locks. These changes might require modifications to the home. Therefore, the landlord might not want the tenant to make the changes themselves.\nWhen At Home\nEveryone should feel safe at home. While the chances of a break-in, home invasion or theft is relatively low for most people, that doesn't mean you shouldn't take proper safety precautions when at home.\nAlways keep the doors locked. This is especially true in apartment complexes, where there might be a lot of foot traffic.\nOnly open ground-floor windows if they have safety screens installed. Never leave your doors open.\nWhen not outside, keep gates, sheds and basement doors shut and locked.\nConsider installing a portable security camera. Systems like Wyze© or Ring© smart cameras can send security footage to your smart phone. You can take these items with you when you move, and they require minimal installation.\nFor added safety, buy removable door & window jammers. You can also buy sensors that will alert you if someone opens a door or window.\nUsually, your landlord must ask permission before entering your property or sending over a maintenance service. Therefore, ask that they tell you before someone comes to the property.\nDon't keep your most-expensive items on clear view for passersby to see.\nWhen Away\nWhenever you leave home, either for an errand or\nfor a vacation, lock down the home. Some of the steps you might take include:\nBring inside outdoor furniture and equipment. Lock your gates and outbuildings.\nHide your valuables. You can choose to put items like jewelry, collectibles, identity-sensitive information and credit cards in a safe. However, conceal the safe as well, so that a potential thief cannot easily find it.\nSet a timer on certain lights (or even your TV) so that they will turn on and off at certain hours.\nHave someone you trust collect your mail and newspapers. If these items accumulate, thieves might take it as a sign that no one is home.\nKeep your travel plans off social media.\nDon't Forget To Buy Renters Insurance\nYou can't prevent every type of property theft, no matter how hard you try. That's why most renters buy renters insurance. Coverage can include\npersonal possessions coverage for your belongings.\nPossessions insurance can help you recover belongings after a theft or other hazards. You can insure possessions for a certain value, then your renters policy can compensate you in case of theft. Keep in mind that limits and exclusions will exist on most renters policies.\nTalk to your BluCanopy agent about whether you need to buy special endorsements or riders to expand your possessions coverage.", "pred_label": "__label__POS", "pred_score_pos": 0.6893322467803955}
{"content": "\"This is stripped to a single raft, endlessly bobbing through the sea,\" says one player about the game. While one might expect this statement to be a set up for a bad review, it's actually the exact opposite. \"And I've loved it!\" finishes the Raft game fan. Raft begins by placing a single player and his or her friends (if multiplayer) at sea on a small plank of wood with nothing but a single hook made of plastic.\nWhen players come to, all they see is an endless ocean, a frightening and daunting situation even for those with the sturdiest of sea legs. Avatars are parched and in dire need of sustenance. Players' objectives? To help their avatars survive.\nLittering is a detriment to the environment as a whole, but it's safe to say that no other terrain suffers so much from humans' carelessness as the ocean. Raft creators who, at the time of creation, were three university students thrown together to work on a class project decided to use this fact to their advantage by placing a faceless character at sea with nothing but a piece of driftwood and a hook-shaped piece of garbage.\nThe goal? For drifters to catch whatever debris floats by and use it to build themselves a floating home worthy of survival. In this video game, it seems that to come across the Great Pacific Garbage Patch would be a lucky happenstance. Initially, floating patches of garbage contain simple objects avatars can use to create tools, which they can then use to capture food and water.\nHowever, over time, as gamers grow stronger, the emphasis becomes less on satiating hunger and thirst and more on creating a self-sustaining environment at sea. It is then that players begin to notice more complex pieces of garbage coming their way.\nPlayers are also encouraged to dive beneath the surface and scavenge trash-laden reefs for useful resources. If they happen to find tasty-looking sea life down in the depths, even better.\nFor players whose idea of fun does not involve floating on an endless horizon and digging for trash, the game offers a bit more excitement beneath the surface. While the raft floats, a man-eating shark circles below.\nIf players aren't vigilant, the shark can take a bite out of the hard-worked-for additions to the unanchored shelter. Occasionally, the shark will try to get a taste of any player who tries to swim a few yards to capture a piece of, particularly appealing debris or who wants to snag a bite to eat from the teaming reef below.\nFor some players, trying to survive in shark-infested waters is too stressful to do on a consistent basis. Yet, these players find solace in building extensive shelters from random odds and ends they happen to encounter in their drifting. The compromise? A creative mode.\nIn the early days of the game, Raft creators implemented a creative mode that simply allows competitors to build magnificent seafaring structures using their wits and debris.\nDebris may include palm fronds, wood, plastic, rope, and metal. With these pieces of scrap, more ingenious Raft players develop tools and building materials they then use to create what are essentially houseboats, replete with beds, raised gardens, tables, porches, propellers, grills and other staples you might find at a land-based abode.\nIf players can get beyond the fact that they're drifting for no other apparent reason than to survive, they'll eventually spot something that looks a lot like land or a wrecked vessel. Are their eyes deceiving them? No, they're not.\nUpdates to the game brought with them small islands and abandoned vessels, which, if they can get to them, avatars are free to explore and loot for whatever items they need. These updates are particularly notable, as many derelict ships contain metal and pieces of waterlogged tech equipment that avatars can dry out to create electronic equipment that actually works. Think sonar, GPS and receivers that allow players to navigate rather than aimlessly drift.\nThe Large Island Update, a newer update, plays a key role in the new advanced cooking system. This system allows players to sustain avatars' hunger for much longer by eating meals that consist of ingredients found both at land and sea. The system includes 11 new recipes, which players can locate in crates hidden at rare locations.\nThe large islands contain a plethora of resources that the smaller islands, reefs and garbage patches don't, such as berries, mushrooms, cooking pots, stoves and more. Because of this, the creators don't make it easy for avatars to access these lands.\nBefore they can ground their vessels, players must battle the Screecher, a phoenix-like bird that can be found circling and protecting the new large islands. If the Screecher spots an avatar, it will attack onsite and bombard him or her with rocks. Players can defeat the Screecher by shooting it down with a bow and arrow (which, hopefully, the shark didn't nab) or during a spear battle.\nIf players think they can get around the Screecher by simply diving beneath the surface, they're wrong. A poisonous pufferfish roams around both the large islands and nearby reefs, protecting valuable resources. As with the Screecher, players must combat the pufferfish and prevail to access resources beyond.\nVideo gamers can only catch debris and avoid dangerous sea life for so long before growing bored. In response to demands for more, Raft game creators have implemented several new modes, including game mode, peaceful mode, an updated hard mode, third-person mode, and no-clip mode.\nThe game mode upgrade allows players to equip their rigs with armor and upgrade security so that, as they encounter other (sometimes volatile) players, they can focus more on protecting their home fronts than on pesky shark attacks.\nFor some, watching an avatar float on a raft sounds about as fun as watching paint dry. However, for those gamers willing to stick it out beyond the initial survival mode, Raft can be a stimulating game that provides the opportunity to exercise their creative juices and have a bit of virtual excitement.", "pred_label": "__label__POS", "pred_score_pos": 0.5074852705001831}
{"content": "In 1997, the Colorado Legislature established the Colorado Noxious Weed Management Fund to provide additional financial resources for on-the-ground noxious weed management. Organized private interests, conservation districts, municipalities, and counties have been eligible to apply for assistance provided that awarded funds are used to enhance weed management efforts within the State of Colorado.\nInvasive Species Resources Displaying 1 to 6 of 6Search Help\nColorado Department of Agriculture.\nIdaho State Department of Agriculture.\nThe primary purpose of the Idaho State Department of Agriculture's (ISDA's) noxious weed cost share grant program is to accelerate the attack on invasive weeds by supplementing local funds and resources, not replacing them. Cost sharing is also intended to provide additional incentives for local landowners, officials, and citizens to work collaboratively to develop a more comprehensive and effective noxious weed management program.\nMinnesota Department of Natural Resources.\nMinnesota Department of Agriculture.\nCounties, municipalities, and weed management entities (including weed management areas) may apply for grants to address noxious weeds and invasive plants, with priority given to Palmer amaranth or other species on the Prohibited-Eradicate Noxious Weed List. This grant request is not to be confused with the Cooperative Weed Management Area (CWMA) grant program administered by the Minnesota Board of Water and Soil Resources (BWSR).\nNew York Department of Environmental Conservation.\nThe newly consolidated Invasive Species Grant Program combines previous opportunities, such as the Aquatic Invasive Species Spread Prevention and the Aquatic and Terrestrial Invasive Species Early Detection/Rapid Response grants, to create a single grant program designed to support projects that target both aquatic and terrestrial invasive species. In addition, the Invasive Species Grant program allows applications for two new categories: Lake Management Planning and Aquatic and Terrestrial Invasive Species Research.\nCalifornia Department of Fish and Wildlife.\nThe Funding Opportunity for the U.S. Fish and Wildlife QZAP FY2020 has officially been posted. The total funding amount for projects is approximately $1,830,000.00, which is a significant increase from years past. This opportunity will be open for application through\nOctober 18, 2020.", "pred_label": "__label__POS", "pred_score_pos": 0.6433463096618652}
{"content": "With a delinquency rate reaching the highest level since the Great Recession, auto loan debt has become serious business for lenders and the agencies that represent them. The factors leading to this decline include a record-high sum of newly originated auto loans ($584 billion in 2018), a record-high average price per vehicle ($37,577 in December…Details\nPredictive modeling is used in many aspects of life today. For example, a fisherman can use predictive forecasts to determine the patterns of fish to find the best times and locations to get the most action. Similarly, in the world of collections, there are many fish in the sea with agencies challenged to handle massive…Details\nThe Association of Credit and Collection Professionals (ACA International) presents its annual conference July 14 – 16, 2019 at the Hilton San Diego Bayfront. The ACA International Convention & Expo 2019 features 35 educational sessions led by industry experts, an exposition hall showcasing innovative industry providers, and several opportunities to share best practices with peers…Details\nCollecting on accounts receivable can bring in sizable amounts of revenue to clients, but third-party debt collection agencies should maintain a compliance management system (CMS) to provide legal compliance and other benefits. First, a CMS enables agencies to remain compliant with federal, state and local laws that protect consumer interests. The approach ensures that every…Details\nLaunching and maintaining best-in-class debt collection agencies requires a tremendous effort and an ongoing commitment to compliance, certification, data security, and collections technology. Recent articles in this blog have also discussed the importance of having highly qualified people in client relations and operations. Client relations teams are responsible for ensuring that clients are satisfied with…Details\nProduced by insideARM, the 2019 First Party Collections Summit will focus on the unique challenges of first party collections, outsourcing collections management, and the consumer experience. The event is scheduled for June 17 – 19 at the Loews Vanderbilt Hotel in Nashville, Tenn. Over 350 first party partners are expected to attend, including 100-plus creditors and 100-plus collection agencies.Details", "pred_label": "__label__POS", "pred_score_pos": 0.698973536491394}
{"content": "As of March 2020, everyone was asked to work from home where possible. This current shift in situation presents not only technological but also human factor challenges for information security. Organizations will have to tailor their awareness campaigns and training to target issues specific to working from home, confronting new security-based obstacles that their employees and clients might be facing.\nIn order to maintain both personal and organizational security, individuals must perceive information security risks realistically. However, people’s judgments regarding information security risks are influenced by a wide range of cognitive biases.\nCognitive biases are inherent characteristics of human nature and are present in everyday life. Biases refer to a predisposition to think a certain way, and affect our subsequent decisions, judgments and behaviors.\nThese biases often arise when we interpret risk and make decisions, particularly in times of uncertainty. There is a plethora of cognitive biases that have impact and consequence on the way we perceive information security risks. Here I will discuss two cognitive biases: optimism bias, and fatalistic thinking.\nOptimism bias and information security\nOptimism bias is sometimes used interchangeably with ‘overconfidence’, and refers to the phenomenon whereby individuals believe they are less likely than others to experience a negative event. This particular bias is said to transcend age, race and gender.\nFor example, experts have demonstrated the presence of the optimism bias in the beginning of the COVID-19 crisis. Research has revealed that, at least at the start of the outbreak, people underestimated their own risk of becoming ill or passing on the virus.\nOptimism bias has further been demonstrated in information security risk perceptions. There are many reports that individuals perceive their risk to information security attacks, such as phishing, to be lower than others.\nA recent poll of 2000 remote workers revealed that 77% said that they weren’t worried about security while working at home. This also extends to organizational contexts, where individuals believe their own organization to be at relatively lower risk to information security threats than other competitor organizations.\nFatalistic thinking and information security Fatalistic thinking refers to an outlook where individuals may believe they have no power to influence risks personally, as risks are controlled by external forces. In information security, this might mean believing there is nothing you can personally do to prevent a phishing attack, because you’re going to fall victim to a phishing attack anyway. Or believing that everything is ‘hackable’ and so there’s little point in protection efforts.\nThis feeling may augment with home working, as employees are distanced from usual organizational support.\nWhy is this important?As seemingly opposite as fatalistic thinking and optimism bias sound, they both stem from misinterpretations of risk and can lead to similar behavioral consequences. Individuals can both be optimistic about their own risk and believe that they have no power to reduce the risk anyway.\nIn addition to resulting in incorrect perceptions, optimism bias and fatalistic thinking can lead to increased vulnerability. If individuals are optimistically biased regarding information security threats, they may not take the precautionary measures to reduce risks. Similarly, if individuals believe risks are dictated solely by external forces, this will also reduce precautionary action. Both these biases can therefore actually increase risk.\nHow might we reduce the increased risk biases pose?Although these biases are heavily engrained, all is not lost. Instead of seeing the human as the ‘problem’, empowering employees to be part of the solution to information security issues might be a way forward.\nIt may help to take a ‘human as a solution’ approach to information security. In information security, humans are often viewed as the biggest issue. Therefore, efforts are made to exclude and control them. This removes the opportunity for individuals to contribute to their organization’s cybersecurity.\nIt is really no surprise individuals demonstrate perceptual biases if they are made to feel like the weakest link. Instead, organizations should learn from and involve employees in information security.\nFor example, organizations could ask employees the information security risks and problems they might be experiencing, or envisage experiencing, when working from home.\nFirstly, this could reduce fatalistic thinking by demonstrating how employees can play an active role in reducing information security risks. Secondly, this could reduce optimism bias through awareness of security issues and by learning from a positive attitude. Hence, learning from employees could increase overall security.\nUnderstanding biases may also help organizations tailor information and training. Training people to understand and cope with the risk should be at the forefront. Especially in the case of fatalistic thinking, organizations might endeavor to remove fear appeals as a method for communication and increasing feelings of morale and employees’ abilities to cope with threats.\nSummary Overall, cognitive biases such as unrealistic optimism and fatalistic thinking are present in our everyday lives and can have negative impacts for risk mitigation. However, cognitive biases are normal mechanisms in human thinking and viewing the human as a solution, rather than a problem, could perhaps in itself mitigate any risks biases pose.", "pred_label": "__label__POS", "pred_score_pos": 0.508575439453125}
{"content": "We like sharing natural insomnia remedies with our readers - so here's another one to start the week.\nA recent study published in the Journal of Biological Chemistry found that two specific fragrances, vertacetal-coeur (which is derived from jasmine) and its chemical alternative PI24513, were just as powerful as sedatives such as benzodiazepines and barbiturates.\nThe study is being hailed as proof that there is a scientific basis for aromatherapy - however, we want to wait for future studies to be released before jumping on that bandwagon. If you're interested in learning more about this specific study, the United Kingdom's NHS website does a good job of offering a balanced analysis.\nOf course, you shouldn't change your medication based on this study - but you might want to consider exploring aromatherapy as a natural insomnia remedy.\nWhat have you got to lose?\nLast updated: August 2, 2010", "pred_label": "__label__POS", "pred_score_pos": 0.9780040383338928}
{"content": "A large pharmaceutical company’s multiple manufacturing science and technology department teams operated from locations around the globe. Common goals of these teams required collaboration and information sharing to achieve results, but the groups were experiencing conflict, competition, lack of trust and breakdown in communication. Results were sub-par.\nContinuum worked with an internal team to survey key members and gain a better understanding of situation dynamics.\nThe first priority was to improve work relationships between a specific U.S. team and one in Ireland. The Continuum Consultant designed a nine-month intervention that included multiple components:\nGroups crafted an Ongoing Engagement Plan with shared agreements for working together, a process of accountability and agreed-upon methods for addressing potential conflict or lack of understanding before negative effects manifested.\nIn addition, the groups designed Action Plans, including timelines, that laid out group recommendations for improvements to present to management.\nUpon reviewing program outcomes and the teams’ new working processes, their department leader stated that the increase in communication and trust were already evident. At this time, informal reviews show positive results have been maintained.", "pred_label": "__label__POS", "pred_score_pos": 0.5769419074058533}
{"content": "Operational principles for integrating IHBC’s research, guidance and advocacy for the production of Standards: A strategy for evidence-based conservation standards in the IHBC Drafts approved by IHBC’s Committees for Policy and for Education, Training and Standards, 2014 Context: Standards in practice and quality assurance\nThe need to value of standards in the discipline of conservation is acknowledged in the IHBC’s Corporate Plan 2010-15 (CP 10), Action 2.1:\n‘Produce framework for development and adoption of standards appropriate to the IHBC as an interdisciplinary professional body.’\nStandards are a fundamental tool in professional processes. Standards can play especially critical roles in conservation by:\ngenerating efficiencies in the delivery of conservation, by representing agreed and consolidated principles of practice, and helping in the scrutiny of that practice within quality assurance processes.\nThis note explains how the IHBC can integrate its core activities and unique resources to achieve its corporate objectives through a focus on evidence-based conservation standards.\nIssue: Challenges for interdisciplinary standards\nConservation is inherently an interdisciplinary activity (ICOMOS 1993). Barriers to that interdisciplinary activity will threaten successful conservation. Unless standards reinforce practice inclusively across the relevant disciplines they may be seen as obstructive to the delivery of outcomes rather than as conclusive statements on how to secure those outcomes.\nTo date, conservation standards usually have been based on a description of practice, often based on judgement within a particular discipline. If standards remain no more than the description of a judgement within one or more select disciplines, they are unlikely to be adopted as the definitive statement on the effective delivery of sustainable conservation outcomes.\nHowever, if conservation standards are based on sound evidence, they will offer a secure foundation for their adoption by all parties involved in the delivery of conservation, regardless of practice or discipline.\nIHBC’s evidence-based standards for conservation professionals\nEffective conservation standards should be developed out of research-based evidence supported by practice-based guidance. Sound evidence must be developed within a credible evidence-based research process. However that research can underpin practice only where proven in operation. Testing of evidence-based practice standards takes place through the development and operation of guidance for practitioners.\nConsequently, the IHBC’s development of standards will begin with developing research that generates evidence to shape practice through guidance that, when tested, underpin standards.\nIn summary, the IHBC will develop its standards as follows, by:\nPromoting research, gathering data to establish Evidence Developing Evidence into Guidance that shapes Practice Testing Guidance, in Practice, to underpin Standards IHBC priorities for production of standards – Strategic: Advocacy\nThe IHBC is uniquely placed to integrate conservation research, guidance and standards to deliver advocacy supporting conservation outcomes. The IHBC’s priorities in planning for research, guidance and standards, consequently, are shaped by their potential to deliver advocacy.\nPrinciples in identifying and interpreting evidence\nAs conservation is an interdisciplinary process, the nature and scope of the practice of conservation is necessarily diverse.\nTo ensure that the IHBC’s strategy for developing standards is fit-for-purpose, appropriate interpretation strategies must be identified. Specific approaches are justified for use by the IHBC where they sit within the recognised framework of evidence-based conclusions as follows:\nEvidence includes empirical, for example based on practice Methodology includes heuristic, for example using aggregated evidence Logic includes inductive, for example though indicative conclusions. Summary: communicating & promoting evidence-based standards\nSuccessful advocacy depends on the promotion of credible standards based on an accessible evidence base that informs practical guidance.\nThe IHBC has a critical communications role in delivering that advocacy by promoting all aspects of evidence-based standards across its networks:\nResearch Papers: Present evidence Guidance Notes: Inform practice Standards: Underpin outcomes Collectively: Generate Advocacy IHBC, 16 October 2014 PDF download of above document", "pred_label": "__label__POS", "pred_score_pos": 0.8529465794563293}
{"content": "New York — WattBuy, an online electricity marketplace that empowers consumers to make smarter decisions about their electricity costs by allowing them to browse and select plans in their area, announced it has raised $3.25 million in its Series A round of funding led by Evergy Ventures. Additional investors include Updater, Avesta Fund, Yoav Lurie, John Sherman, and Bill Gatreaux.\nExisting investors also participating in this round include Fort Ventures, Techstars Ventures and Powerhouse Ventures.\nEach investor brings a significant track record in supporting innovative companies that create solutions to decarbonize and democratize the energy value chain.\n“We are thrilled to have leading energy technology investors recognize WattBuy’s contributions to energy innovation,” said Naman Trivedi, CEO and co-founder of WattBuy. “These funds enable us to expand our turnkey API offering within market-leading real estate platforms like Updater as well as personal finance companies and energy services businesses. We’re enabling enterprises to launch their own renewable electricity marketplaces that can increase value to their existing customers.”\nWattBuy’s Series A funding round follows the successful launch of the first-ever calculator to estimate the electricity cost and carbon footprint impact for nearly every home in the United States.\nThis calculator incorporates several open and proprietary data sources to build a machine learning model that takes location, building characteristics, and weather data as inputs, and returns an hourly electricity usage prediction. WattBuy will continue to improve this machine learning model with the funding from this round.\n“WattBuy is providing an important service to consumers by helping them find the best electricity plan for them, including factors such as price and sustainability,” said Dennis Odell, vice president at Evergy Ventures. “We are thrilled to be partnering with WattBuy, a company that shares our passion for clean, safe, reliable energy solutions, as it expands its offering to enterprises.”\n“Moving signals an important inflection point for electricity – the start and stop of service,” said David Greenberg, founder and CEO of Updater. “WattBuy’s transparent full-market views and innovative purchase experience will allow Updater movers nationwide to shop for and turn on electricity more efficiently than ever before. We’re thrilled to partner with WattBuy on such a compelling use case.”\n“Consumers have long desired greater choice in their energy decisions,” said Yoav Lurie, founder and CEO of Simple Energy, which merged with Tendril to form Uplight. “WattBuy really shines for its ability to reach consumers when they are making energy decisions. I’m excited to see them partnering with enterprises to scale their reach across the U.S. and enhance the customer experience at this critical time in the marketplace.”\nOver the past two decades, several state governments have deregulated their electricity markets, allowing residents to choose who provides their electricity. Today, over 140 million Americans in 14 states can use WattBuy to choose among over 100 electricity providers and approximately 5,000 plans to find one that matches their preferences. On average, these residents could save $360 per year by selecting a less expensive electricity provider.\nEarlier this year, WattBuy initiated a Schmidt Futures-funded project in partnership with the U.S. Department of Energy’s National Renewable Energy Laboratory (NREL) to create the nation’s first complete, up-to-date database of electricity rates.\nSince its founding in 2017, WattBuy has raised a total of $5 million in venture funding. The company closed its $1.5 million seed round in July 2019.", "pred_label": "__label__POS", "pred_score_pos": 0.6364030838012695}
{"content": "Across the United States, many voters have already cast their ballots for the 2018 midterms during their state's early voting period. In one state, Georgia, early voting turnout has far surpassed its previously record-breaking 2014 early voting rate. This strong early voting turnout brings further attention to the state, which is already being closely watched because of its potentially history-making gubernatorial race.\nOn Monday, Georgia's Secretary of State, Brian Kemp (who is also the state's Republican gubernatorial candidate) revealed in a statement that Georgians cast 2,071,830 ballots during the state's early voting period, which ended on Nov. 2. This number dwarfs the state's previous record for midterm early voting turnout, which consisted of 945,507 voters casting early voting ballots in 2014.\nIn the same statement, Kemp expressed pride that turnout had been so strong during Georgia's early voting period. As the Secretary of State described:\nIn Georgia, it is easy to vote and hard to cheat, and I am incredibly proud of this new record showing strong voter engagement leading up to tomorrow’s election. This milestone is a testament to the hard work of thousands of election officials all across Georgia who are dedicated to secure, accessible, and fair elections for all.\nGeorgia is home to a gubernatorial race that is being closely followed by the state's residents and beyond. In the race, Kemp is facing Democrat Stacey Abrams. The latter could become the first-ever African American woman governor in the United States if she secures victory on Tuesday.\nIn addition to its possibly history-making race for governor, Georgia has also received a lot of attention because of its voter purge last year, which was spearheaded by Secretary of State Kemp. As American Public Media reported, in 2017, over 100,000 voters were removed from the voter registration rolls for failing to make contact with election officials or vote within a designated period of time. The outlet noted that many of these voters were not aware that they had been removed from the rolls, meaning they could think they are eligible to vote on Nov. 6, but will instead be turned away at the polls.\nGeorgia is not the only place where early voting has been exceedingly high. As\nPolitico reported on Nov. 5, across the United States, a total of 36 million voters have cast early voting ballots. This number far outpaces the nationwide early voting turnout for 2014's midterms, in which 27.2 million people cast their ballots ahead of Election Day. In three states, Arizona, Nevada, and Texas, early voting rates are higher than each state's entire turnout for the 2014 midterms.\nAs\nPolitico noted, it is not yet certain what these record-breaking early voting numbers mean for Election Day turnout or for the prospect of Democratic versus Republican victories on Tuesday. However, generally, experts seem to agree that this election is quite unique in terms of voter turnout. \"This is not a normal election,” Michael McDonald, a professor at the University of Florida who tracks voter turnout, told Politico. “The best guess is that we’re looking at some sort of hybrid midterm/presidential election [in regard to turnout].\"\nOverall, the 2018 midterms appear to already be making history as a result of strong early voting turnout, in Georgia and beyond. It remains to be seen how the rest of the midterms' story will unfold as voters around the United States head to the polls on Tuesday.", "pred_label": "__label__POS", "pred_score_pos": 0.8313656449317932}
{"content": "Hooding of the upper eyelids is a common concern amongst my Houston upper eyelid surgery patients. As we age, we lose elasticity and collagen in our skin. This is most evident around our eyelids, the thinnest skin in our body. Hooding of the upper eyelids may begin with patients in their 30’s depending on their skin type. Hooding of the eyelids refers to excess skin overhang on the lateral or outside portion of the upper eyelid. This may give the appearance of tired eyes, or heavy eyes. Hooding of the upper eyelids may also make placement of eye shadow and mascara difficult.\nIn addition to the aesthetic concerns that may occur with upper eyelid hooding, some patients complain of peripheral visual loss due to this issue. Although Dr. Funk does not take insurance for upper eyelid surgery, upper blepharoplasty should improve vision if you have significant hooding of the upper eyelids.\nTreatment for upper eyelid hooding can be non-surgical and surgical. Botox or Dysport injections can weaken the brow depressing muscles and lead to a slight lift of the tail of the brow helping with hooding. This is not as significant as a surgical brow lift, but can lift the brow by 1-2mm.\nIf the issue with hooding of the upper eyelid skin is due to heavy brow skin, a temporal brow lift is a surgical option for this issue. With a temporal brow lift, an incision is made behind the hairline in the temple and the skin is elevated to the brow. The muscle above the brow is suspended to the firm fascia and a small amount of excess skin is excised.\nWith most patients, upper eyelid hooding is simply due to excess upper eyelid skin laterally. An upper blepharoplasty or upper eyelid surgery can address this issue. Excision of this excess hooded skin is performed and the scar is hidden nicely in the eyelid crease and crow’s feet. This procedure can be performed under local anesthesia or slight sedation. Recovery is 5-7 days.\nFor further information regarding upper eyelid hooding in Houston, contact Dr. Funk’s office.", "pred_label": "__label__POS", "pred_score_pos": 0.5233821272850037}
{"content": "Radislav Nakov* and Tsvetelina Velikova Pages 260 - 269 ( 10 )\nAmong the gut microbiota’s newly explored roles in human biology is the ability to modify the chemical structures of foreign compounds (xenobiotics). A growing body of evidence has now provided sufficient acumen on the role of the gut microbiota on xenobiotic metabolism, which could have an intense impact on the therapy for various diseases in the future. Gut microbial xenobiotic metabolites have altered bioavailability, bioactivity and toxicity and can intervene with the actions of human xenobiotic-metabolizing enzymes to affect the destiny of other ingested molecules. These modifications are diverse and could lead to physiologically important consequences.\nIn the current manuscript we aim to review the data currently available on how the gut microbiota directly modifies drugs, dietary compounds, chemicals, pollutants, pesticides and herbal supplements.\nXenobiotics, gut microbiota, drug metabolism, pollutants, bioavailability, bioactivity, toxicity.\nClinic of Gastroenterology, Tsaritsa Yoanna University Hospital, Medical University of Sofia, Sofia, Clinical Immunology, Lozenetz University Hospital, Sofia", "pred_label": "__label__POS", "pred_score_pos": 0.5191197395324707}
{"content": "Please note that all resources below are written, filmed or nominated by PwPs, these are for your information only and are not offered as medical advice. Slowness and Stiffness\nSlowness of movement (bradykinesia) is a separate symptom to stiffness and rigidity; but these symptoms can impact each other.\nA recent survey highlighted some common features of\nslowness of movement and stiffness and rigidity: Slowness of movement Poor mobility Legs not moving Reduced reaction time Standing still Stiffness and rigidity Muscle tension/tightness Reduced flexibility Mask-like face (often noticed as a reduction in smiling) Dystonia (painful muscle spasms sometimes described as cramping, curling or seizing up) Sofa to Standing Foot dystonia", "pred_label": "__label__POS", "pred_score_pos": 0.5146540999412537}
{"content": "AAKG Revolution is raw, unflavored arginine alpha-ketoglutarate. L-Arginine is a conditionally essential amino acid and a chemical precursor to nitric oxide, a blood vessel widening (vasodilating) agent.\nBenefits\nImprovements in blood flow leading to a bigger “pump.” Increases muscle mass Reduces body fat Stimulates muscle protein synthesis Supports cardiovascular health\nDirection of use\nrecommended serving size 1-2g, twice a day. One serving in the morning and one serving 45 minutes before training for best results. Arginine Alpha-Ketoglutarate (AAKG) can either be taken on its own or added to your protein shake.", "pred_label": "__label__POS", "pred_score_pos": 0.5209417343139648}
{"content": "Like many design firms, UK based Frip Design and Research is exploring the innovations made possible by 3D printing technology. Their latest endeavor is developing 3D printed prosthetics, which could significantly reduce the normal time and cost necessary to supply patients in need. While the design stage is relatively complex, the entire process including printing takes less than 2 days – significantly less time than the average 10 week wait that many patients have to endure.\nIn an interview with Dezeen, Tom Fripp of\nThe prosthesis is then printed with a Z Corp 3D color printer using compatible starches and medical grade silicone, which is colored to match the patient’s skin tone. The prosthesis can then be snapped into place and sealed with a medical adhesive.\nEven though the prosthesis can be produced months before a regular handmade one would be ready, the cost of the pieces is only slightly lower than normal. This is due to the extensive mapping and design necessary for each individual face. After the initial design file is made though, replicas and replacements are significantly cheaper. Prosthetic eyes are the exception; since the size and shape of eyes are typically constant, the same pattern can be used repeatedly to produce prosthetic eyes at less than 10% of the typical cost.\nWhile the prostheses have been fitted to patients and the technology is ready, Fripp Design is still involved in the long process of medical accreditation. Frip estimates that the prosthetics could be available to the public within a year.", "pred_label": "__label__POS", "pred_score_pos": 0.5019090175628662}
{"content": "The optical fiber technologies have considerably improved in the current times. It's in fact among the latest technologies that are used in communicating.\nThe excellence of this technology was instrumental in the inventions in the field of communicating. You can even take help from the\nProfessional Detectors Expert for the optical fiber systems.\nThe use of these technologies in telecommunication systems, information systems, and cable television transmission has contributed to the efficacy factor of these regions.\nThe scientific program and technology of optical strands is the simple idea behind these systems.\nThe high speed of information transmission has greatly led to rapid and efficient communication in a variety of fields.\nThe light signals are composed within the crux of the thread and making the machine more efficient compared to other systems.\nThe information signs often diminish in different systems. The greater spend compared to conventional techniques is also one of the factors for its use from the long-distance data transmission.\nSeveral distinct kinds of optical cables are utilized in the communication situation today. A fundamental optical cable includes two layers.\nThe middle component of this strand is referred to as the center. The signs in the kind of light beams traveling through the crux of the strand.\nThe protective shield beyond the heart is referred to as cladding. The major purpose is protecting the heart from intense interference.\nCladding also functions as the inner reflective border that permits complete internal reflection. It's also the crucial factor as it empowers the signals to journey towards the ideal path towards destination.", "pred_label": "__label__POS", "pred_score_pos": 0.5155515670776367}
{"content": "Abstract\nThe plasma concentration of atrial natriuretic polypeptide (ANP) was measured in nine patients with essential hypertension during two grades of exercise tests performed in the supine position on a bicycle ergometer. The plasma ANP concentration significantly increased from 97.0 ± 19.2 pg/ml to 107.6 ± 23.7 pg/ml (p < 0.05) during low-grade exercise (50% of the maximal heart rate) and from 96.2 ± 16.5 pg to 192.8 ± 30.7 pg/ml (p < 0.01) during high-grade exercise (75% of the maximal heart rate). During high-grade exercise plasma epinephrine and norepinephrine concentrations showed significant increases. The plasma ANP concentration was significantly correlated with systolic blood pressure (r = 0.51; p < 0.05). Patients with essential hypertension showed greater absolute increases in the plasma ANP concentration and systolic blood pressure during exercise compared to normotensive subjects. These results suggest that exercise stimulates secretion of ANP in response to its intensity in patients with essential hypertension and that a greater rise in atrial pressure, resulting from a greater elevation of systolic blood pressure, may be involved in the exaggerated secretion of ANP in patients with essential hypertension.\nASJC Scopus subject areas Cardiology and Cardiovascular Medicine", "pred_label": "__label__POS", "pred_score_pos": 0.8267136812210083}
{"content": "Abstract\nBackground Functional and structural damages in sinusoidal endothelial cells (SECs) have a crucial role during hepatic ischemia-reperfusion injury (IRI). In regulating endothelial function, sphingosine-1-phosphate receptor 1 (S1PR1), which is a G protein–coupled receptor, has an important role. The present study aimed to clarify whether SEW2871, a selective S1PR1 agonist, can attenuate hepatic damage caused by hepatic IRI, focusing on SEC functions. Methods In vivo, using a 60-min partial-warm IRI model, mice were treated with SEW2871 or without it (with vehicle). In vitro, isolated SECs pretreated with SEW2871 or without it (with vehicle) were incubated with hydrogen peroxide. Results Compared with the IRI + vehicle group, SEW2871 administration significantly improved serum transaminase levels and liver damage, attenuated infiltration of Ly-6G and mouse macrophage antigen-1-positive cells, suppressed the expression of vascular cell adhesion molecule-1 and proinflammatory cytokines in the liver, and enhanced the expressions of endothelial nitric oxide synthase (eNOS) and vascular endothelial (VE) cadherin in the liver (eNOS/β-actin [median]: 0.24 versus 0.53, P = 0.008; VE-cadherin/β-actin [median]: 0.21 versus 0.94, P = 0.008). In vitro, compared with the vehicle group, pretreatment of SECs with SEW2871 significantly increased the expressions of eNOS and VE-cadherin (eNOS/β-actin [median]: 0.22 versus 0.29, P = 0.008; VE-cadherin/β-actin [median]: 0.38 versus 0.67, P = 0.008). As results of investigation of prosurvival signals, SEW2871 significantly increased Akt phosphorylation in SECs and decreased lactate dehydrogenase levels in supernatants of SECs. Conclusions These results indicate that S1PR1 agonist induces attenuation of hepatic IRI, which might be provided by preventing SEC damage. S1PR1 may be a therapeutic target for the prevention of early sinusoidal injury after hepatic IRI.\nAll Science Journal Classification (ASJC) codes Surgery", "pred_label": "__label__POS", "pred_score_pos": 0.6792344450950623}
{"content": "Is there really a difference between observational science, which examines facts in the present, and historical science, which draws conclusions about the past? Not everyone thinks so. The answer has major implications for critical thinking, so let’s unpack the definitions for these two types of science and investigate whether the distinction between them is valid.\nCast", "pred_label": "__label__POS", "pred_score_pos": 0.9720481038093567}
{"content": "For many, college is their first experience attempting to navigate the real world and manage responsibilities, including maintaining a balanced budget. Why would you suggest hindering their development toward full-fledged adulthood like this? I’d venture to guess that ALL college students are low income. I know I was, but I still managed to eat well. Everyday, every moment, we’re faced with the challenge of making good decisions, and with every single one we have to be able to say no to one thing or another. That’s life, and no socialist model will save anyone from that reality. Student loans and feeding students are not the problem we need to address with respect to higher education in our country. The problem is more aptly defined in the skyrocketing costs of education in part driven by seductive amenities and the sensationalist sports culture we promote. Higher education steers further and further away from EDUCATION with every new class of students. We need to realign ourselves and our culture with the heart of education, working with colleges to ensure the integrity of education, reduce costs, and ensure appropriate levels of financial aide provided through their endowments. We need to lessen the need for loans and federal aide by addressing these issues at their source.", "pred_label": "__label__POS", "pred_score_pos": 0.7500315308570862}
{"content": "In this installment of a 13-part series of monthly articles, The Combustion Institute recognizes the 2019 Distinguished Papers selected from among the scientific papers presented during the 37th International Symposium on Combustion. Congratulations to C. Paul, D.C. Haworth, and M.F. Modest for winning the DPA in the Internal Combustion Engines colloquium.\nTheir authoritative paper,\nA simplified CFD model for spectral radiative heat transfer in high-pressure hydrogen–air combustion systems , has significantly improved the ability to accurately calculate radiative reabsorption at a fraction of the computational costs normally required. Using a simplified stepwise-gray model for spectral radiative heat transfer in engines, they provide a less computationally intensive model that captures the essential redistribution of in-cylinder energy and radiative heat loss and that can be used in routine engineering CFD for engine development and design.\nThe researchers envisioned a simplified radiation model that could address the computational cost associated with solving the complex spectral effects of radiative transfer equation. The team created a P1/Stepwise-Gray radiation model and compared it with a simpler, P1/Gray, model and more detailed, PMC/LBL and P1/FSK radiation models. The study demonstrated that the P1/Stepwise-Gray model can compute radiative reabsorption for different engine-relevant operating conditions with less than 10% error, while the error for a P1/Gray model is as high as 60% compared to the detailed radiation models. The computational cost of the P1/Stepwise-Gray model is approximately 15 times lower than that of P1/FSK and 30 times lower than that of PMC/LBL.\nWhile the focus of the team’s study was diesel engines, they believe the proposed radiation model could be broadly applicable to other high-pressure hydrocarbon-air combustion systems, such as gas turbines and rocket engines.\nThe work supporting this paper began approximately in March of 2017 and concluded in November of 2017. The research was conducted mainly in the Mechanical Engineering Department of the Pennsylvania State University, with collaborative support from Professor M.F. Modest of University of California Merced. Their work was supported by the U.S. Department of Energy (DOE), Office of Energy Efficiency and Renewable Energy (EERE), the Department of Defense, Tank and Automotive Research, Development, and Engineering Center (TARDEC), and U.S. National Science Foundation (NSF).\nThe team believes their findings will help the scientific community to accurately model the radiative heat transfer of a high-pressure hydrocarbon-air combustion system at an affordable computational cost.\nOver 1,600 papers were submitted to the 37th Symposium in 13 combustion science colloquia. Those papers were categorized by teams of colloquium coordinators and co-chairs, and then distributed to approximately 1,000 scientific reviewers. One paper in each discipline was awarded the recognition of Distinguished Paper.\nThe 13 Distinguished Papers undergo committee review for consideration to receive the Silver Combustion Medal that will be awarded during the 38th International Symposium in Adelaide, Australia. A paper selected for this honor exemplifies quality, achievement, and significance to advance a field of combustion science. Distinguished papers are selected biennially from among the scientific papers presented during the International Symposium on Combustion and accepted for publication in the Proceedings of The Combustion Institute.", "pred_label": "__label__POS", "pred_score_pos": 0.6751745343208313}
{"content": "The complete SPEC kit is Fee-Based (Order Form).\nFrom a SPEC Kit #326 Summary:\nThe Association of Research Libraries (ARL) has published\nDigital Humanities, SPEC Kit 326, which provides a snapshot of research library experiences with digital scholarship centers or services that support the humanities (e.g., history, art, music, film, literature, philosophy, religion, etc.) and the benefits and challenges of hosting them. The survey asked ARL libraries about the organization of these services, how they are staffed and funded, what services they offer and to whom, what technical infrastructure is provided, whether the library manages or archives the digital resources produced, and how services are assessed, among other questions.\nThis survey revealed that library-based support for the digital humanities is offered predominantly on an ad hoc basis. However, as demand for services supporting the digital humanities has grown, libraries have begun to re-evaluate their provisional service and staffing models. Many respondents expressed a desire to implement practices, policies, and procedures that would allow them to cope with increases in demand for services.\nThis SPEC Kit includes documentation from respondents that describes the mission or purpose of digital humanities centers, the services offered, policies and procedures, examples of digital projects, fellowship and grant opportunities, promotional materials, and repositories for digital projects.\nThe executive summary and table of contents are available online, free (14 pages; PDF).", "pred_label": "__label__POS", "pred_score_pos": 0.8400579690933228}
{"content": "Self-defense in a tort is used as a justified legal defense to win a personal injury lawsuit.\nWhat Is Self-Defense?\nIn criminal and tort law, it refers to a defendant’s right to use physical force to defend oneself from bodily harm. It is commonly referred to as a justifiable defense.\nHow Much Physical Force Can Be Used?\nThe amount of force used must be reasonable and match the plaintiff’s force. If the plaintiff threw a punch at the defendant, the defendant could block the plaintiff’s punch with a punch of their own.\nWhat Is the Difference between Self-Defense and Excessive Force?\nExcessive force is physical force that goes too far. In other words, it does not match the level of force the plaintiff threatened to use or actually used. An example of excessive force occurs when a plaintiff punches the defendant. The defendant then shoots the plaintiff in the stomach using a gun.\nWhat Is Deadly Force Involving Self-Defense?\nDeadly force involves using physical force that can or does cause death or serious bodily injury. It can only be used when a defendant is threatened with deadly force without any reasonable way to escape.\nWhen Can a Defendant Claim Self-Defense?\nA defendant can claim this defense when sued for battery or assault. It is also used in false imprisonment cases where a defendant was bound to a certain area without their consent by the plaintiff.\nCould a Plaintiff Win a Tort Claim If Self-Defense Is Used?\nYes, it is possible. Remember, every case is different. A defendant who attacked the plaintiff, exact revenge, or went beyond the level of the threat could lose the case. Also, a defendant who successfully defends themselves, but continues to use force against the plaintiff may also lose their case.\nFor example, a plaintiff punched the defendant. The defendant then punched the plaintiff back before they could land another punch. This is adequate self-defense. However, if the defendant continues punching the plaintiff without any continued threat from the plaintiff, self-defense is no longer a viable defense.\nShould I Talk to an Attorney about Self-Defense?\nIf you are facing a tort action, you should talk to personal injury attorney about the defenses available to you.", "pred_label": "__label__POS", "pred_score_pos": 0.877744197845459}
{"content": "Rapid delivery, with no compromise on quality\nModular buildings equal the durability and quality of permanent buildings, being built to the latest building regulations and planning requirements. The key advantage of modular construction is the significant time saving.\nFor example, a completely new modular office building will typically be ready for occupation up to 50% faster than a traditionally constructed building, or a refurbised option can be ready up to 70% faster.", "pred_label": "__label__POS", "pred_score_pos": 0.8966670632362366}
{"content": "In Australia, over 6,000 adults younger than 65 have been inappropriately placed in nursing homes designed to accommodate older adults. The primary aim of this review was to map the literature on the experiences and outcomes of young people with disability who are placed in aged care.\nThis article was published Open Access, and is redistributed by Summer Foundation under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License (CC BY-NC-ND).\nPublished online: 08 Sep 2020", "pred_label": "__label__POS", "pred_score_pos": 0.7170823812484741}
{"content": "New Jersey woman suffers brain damage following surgery\nJune 14, 2012\nWe hear a significant amount of talk in the news concerning medical malpractice awards. Yet what is often forgotten in such discussions is how significant injuries resulting from medical malpractice can be.\nRecently, a 69-year old New Jersey woman may have suffered a brain injury due to a botched surgical procedure. In what has been described as a “comedy of errors,” an improper incision may have led to internal bleeding and an infection that remained untreated for a number of weeks. Finally, when surgery was performed to address the infection, too much damage had already occurred.\nThe woman had remained hospitalized for her condition for a significant amount of time. She also has since been treated for a number of bed sores. The woman is now confined to a nursing home where she continues to suffer from a significant brain injury.\nWhen patients require surgery, there is always the danger of brain injury if certain safety precautions are not taken. There is always the risk that anesthesia will not be properly administered, or that not enough action is taken to revive a patient that has undergone anesthesia. In the case of the woman mentioned above, there is also the danger of surgical error that can eventually lead to brain trauma.\nExperienced attorneys in the medical malpractice and personal injury areas can address clients concerns if they suspect that someone was injured due to a medical error. Sadly, many such brain injuries that occur due to such a mistake can be catastrophic.\nThis is not the first time that the hospital has been blamed for a medical error. Recently, an organ donor died while planning on donating a kidney to her brother.\nIf hospitals are not held accountable for such injuries, the likelihood of such errors will continue.\nSource: Fox News, “Family sues scandal-hit New York hospital after woman suffers brain damage,” June 12, 2012", "pred_label": "__label__POS", "pred_score_pos": 0.5883505344390869}
{"content": "Social Media\nStrengthen Reputation\nEnforce Loyalty Loop\nGrow Audience\nA Forbes study revealed that 78% of consumers say their purchases are impacted by companies’ social media posts. A strong social media profile is an effective tool for any sales strategy because of the ability to meet people at many stages of the consumer decision journey (CDJ). Social media allows your brand to be at the front of potential consumers’ minds, when considering a service or product. Having a strong profile, with positive reviews, a strong following, and evidence of credibility within the industry, makes you a viable purchasing option. With digital media having such a strong impact, the journey does not end with a purchase. Instead, you want to move them into the loyalty loop, where they will not only continue to patron your brand, but will advocate it to everyone they know. Our social media strategies will create moments for others to advocate organically and put your brand in ongoing dialogue, keeping your brand visible.", "pred_label": "__label__POS", "pred_score_pos": 0.9816272258758545}
{"content": "Despite Effort, Peru’s Covid-19 Response Fails Despite Effort, Peru’s Covid-19 Response Fails\nNEW HAVEN: In March, Peru was among first Latin American countries to introduce containment measures in the region, imposing the most drastic quarantine. International media celebrated the country taking such radical measures, especially given its capacity to launch ambitious fiscal and poverty alleviation policies to balance the economic impact of the containment and secure compliance on social-distancing measures.\nFollowing that line, some argued that “three decades of fiscal discipline and low public debt,” along with steady economic growth, put the country in an advantaged position relative to its peers, not only to spend those resources in the face of a crisis, but also to secure access to favorable credit lines from multilateral organizations. In other words, austerity measures were assumed to be responsible for Peru's favorable position.\nNonetheless, three months later, media outlets report the failure of these measures, stressing the existence of a paradox between the intensity of the containment measures and the virus’ rapid spread among the population. Public health experts and economists highlighted four conditions that explain this paradox: the number of tests, the irregularity of the quarantine, the presence of crowds in markets and banks, and the level of overcrowded housing.\nDue to the wide range in test availability, the comparative picture is imperfect. Peru ranks second in terms of tests for the region, yet public health experts agree that evolution of the country’s infection rates is still incongruent with what would have been expected, considering Peru’s stringent response.\nExperts then turn to three other conditions: the high volume of informal labor, more than 70 percent in Peru; high social and economic inequalities; rooted cultural differences and behavioral patterns that include consistent disrespect for laws.\nWhile all these observations are correct, something is still missing. Such conditions must be seen as symptoms of the real problem rather than independent factors that explain apparent inconsistencies. All those conditions are the effects of a single cause: the persistency of state deficiencies, especially in sensitive social issues. And, as has been argued recently, analysts must consider this major condition, along with the trust in the government, while assessing any administration's performance during this pandemic.\nThe paradox, if any, is that the precarious infrastructural state capacity – especially in issues such as public health and social welfare – before the pandemic explains both the need for radical confinement and social distancing measures and the adverse results after three months of implementation. This problem involves not only the weakness of the state apparatus to provide services and social protections, but also the lack of required social cohesion to contain the pandemic through social distancing. As a result, the government’s efforts have faced severe enforcement and compliance limitations.\nThese deficiencies’ origins are rooted on historical processes of state building that cannot be solved easily. However, the persistency and intensity of such failures in crucial areas nowadays – such as social redistribution, public health and education – can be traced back to the last three decades, precisely the decades when economists praised the “Peruvian economic miracle.” After all, those years of austerity especially constrained public spending on these social goods. Despite the presence of economic bonanza, Peru’s public health spending and social programs coverage rank below average in the region.\nFurthermore, the economic stability of the “miracle” occurred even as the problems listed by the international press intensified. These situations were not unrelated, but complementary. The lack of regulation on informality worked well as a cushion for the social impacts of the austerity policies. While the state introduced social redistribution programs, those prioritized models focusing on rural population, leaving massive portions of urban residents without benefits and vulnerable. Yet, urban families could still rely on the access to precarious, informal jobs, abundant due to the massive consumption produced by the economic bonanza. This informal employment sector did not vanish, but adapted to the pandemic despite the quarantine.\nConfronted by a health and economic crisis, Peru had the resources to invest in improving its precarious health system and introduce relatively high redistributive benefits for those in need during the pandemic. However, the lack of state infrastructure to redistribute those resources in urban areas soon created collateral problems such as the presence of crowds in banks and government offices, aiming to receive benefits or find out if they were eligible for benefits at all. Moreover, the lack of attention to inequality and informality problems reflected on poor urban planning and led to problems of overcrowding and non-compliance that added to pandemic challenges. Today, novice and experienced street vendors flood the streets in major cities.\nClarifying the origins of the paradox is worth noting, since it explains the problems of extreme austerity models for developing countries in the medium and long term. While it is true that responsible monetary and fiscal policies are needed in countries with a history of economic crises, the effects of these measures in the state’s capacity to react to new, pressing challenges such as pandemics or climate crisis must also considered.\nPeru is a poster child for the problems of radical austerity. This is not just a technocratic problem of policy design, but a state capacity one. Money means nothing if governments cannot spend it efficiently. Through the last two decades, several attempts to improve the role of the state have been blocked by a right-wing coalition of conservative politicians, neoliberal technocrats, business organizations and mainstream media. As a result, Peru’s impressive economic growth never translated into the infrastructural and social development the country urgently needs.\nThe government’s response must be assessed given these limitations. Criticism to the specific policies is relevant, but the state’s limitations constrain their efficiency drastically. To be clear, without these measures, the reality would have been worst. Yet, the government and media must undertake the same exercise when assessing the role of individuals. While it is easy to blame the citizenry for complacency and lack of compliance, it must also be acknowledged that such behavior is constrained and shaped by the state’s deficiency to deliver.\nUnfortunately, the prospects for progressive changes might be rather pale. First, electoral politics are highly personalistic and non-programmatic, favoring the rise of neophytes and populists that use these issues in campaign but forget them once in power. Without strong parties, electoral accountability becomes a major problem. Second, citizen’s illiberal values were already on the rise due to perceptions on criminality, corruption and immigration. Then, instead of an opportunity to realize and amend previous mistakes, the pandemic could exacerbate the country’s problems in the years to come. The country’s future lacks advantageous political “credit lines.”\nPaolo Sosa-Villagarcia is a 2019-20 Fox International Fellow at the Whitney and Betty MacMillan Center for International and Area Studies at Yale University and a PhD student with the Department of Political Science at the University of British Columbia. This article was published June 16, 2020.", "pred_label": "__label__POS", "pred_score_pos": 0.6748857498168945}
{"content": "For a long time the formation of protostellar discs — a prerequisite to the formation of planetary systems — has defied theoretical astrophysicists. Now, researchers have made a breakthrough in our understanding of how protoplanetary discs form, demonstrating that chemistry and microphysics are crucial to the fundamental processes underlying star and planet formation.", "pred_label": "__label__POS", "pred_score_pos": 0.9743638634681702}
{"content": "According to the World Health Organization (WHO), at least one in three women worldwide will experience either physical and/or sexual intimate partner violence or non-partner sexual violence in their lifetime. Gender-based violence (GBV) is a global public health epidemic and a violation of fundamental human rights. While GBV can happen to anyone, girls are more likely to experience sexual violence and harassment, as well as harmful practices such as forced marriage and female genital mutilation (FGM).\n5 Things to Know: Under international human rights law, all children and young people have the right to live free from the fear or threat of violence. Yet, violence against children, including GBV against girls, is frequently perpetrated with impunity. Almost universally, support services to mitigate the physical and psychological consequences of GBV are weak and do not address the trauma of survivors. For many children, particularly girls, school is an unsafe place, even though every child has the right to learn in a safe and secure environment. Rates of sexual violence and early marriage increase during a crisis, yet too often, girls in crises do not have access to life-saving information and services that could protect them against early or unintended pregnancies and sexually transmitted infections. Even when services are available, fear of stigma is an obstacle that prevents many girls from accessing care. The increased use of online space has led to abuse, harassment, and violence against children, which are violations of their human rights. The risks that the internet presents for children must not be underestimated. What Needs to Happen: States must recognize violence against children, including GBV against girls, as a significant human rights issue and commit to finding solutions. Legal protections for girls who are victims or at risk of violence must be strengthened, and harmful gender norms that condone the use of violence to control girls’ sexuality and social norms must be challenged. Significant effort is needed at international, national, and community levels to achieve these goals States and multilateral institutions must increase their financial and political commitments. Donors should provide bilateral aid and fund relevant multilateral platforms, such as the Global Fund to End Violence against Children. States must ratify and fully implement, without reservations, all regional and international agreements that relate to violence against children and GBV. States, UN agencies, and civil society must collect better data related to violence. Data must be disaggregated by relevant factors, such as age, sex, location, ethnicity, religion, disability, economic status, marital status, sexual orientation, gender identity, and migratory status. Data must be disaggregated by the distinct age ranges of 10-14 and 14-18 to ensure adolescent and teenage girls and their needs are visible. Sensitive data must be collected and stored in line with human rights considerations and relevant data protection standards. States must ensure that all children, adolescents, and young people, without discrimination, have access to comprehensive sexuality education to gain knowledge and develop the necessary skills to make conscious, healthy, and respectful choices about relationships and sexuality. States must ensure that all survivors of GBV have access to healthcare, including emergency contraception, safe abortion services, and psychosocial support, as well as access to shelter and safe houses if needed, and effective means to seek justice and redress. It is critical that support services do not reinforce harmful attitudes or further victimize survivors in any way. States and community leaders should hold community-level dialogue, engaging men and boys, to change norms, attitudes, and behaviours concerning girls’ rights with the goal of ending violence against girls. States and community leaders should take measures to address attitudes and behaviours that legitimize violence at national, local, school, and community levels to prevent and respond to school-related GBV. States, the private sector, and other relevant stakeholders must increase efforts to ensure children’s online safety.", "pred_label": "__label__POS", "pred_score_pos": 0.5336017608642578}
{"content": "Everyday musings ….Life as I see it…….my space, my reflections and thoughts !!\nTheme – ** Kaleidoscope of thoughts**\nThoughts are nomadic by nature. They enter the mind without permission, at any time of the day or night. Having a strong mind of their own, they can be very adamant at times. They take shape of positive or negative, fleeting or profound, chaotic or structured and at times utterly nonsensical. Some just take a peek and vanish, while some others build a nest and continue to stay on.\nThoughts have something magical in them. They define your temperament and moods. Though you cannot see it, you can feel its power. For they can drain you or pep you up. So be wary of feeding the right kind of thought. Else it will multiply manifold like a parasite, and within no time deflate you.\nMany a time, the thoughts are just images, haphazard and scattered all around. To gather them, dress them with words and present them is a daunting task. While at other times they are so structured and crystal clear, flowing nonstop like a gurgling brook.\nDepending on the words that dress them up, they present themselves in myriad hues and avatars. Be it a garden of vibrant blooms, or a starry constellation, a fiery flame or a tranquil reflection, a profound message or an enigmatic spell!\nThoughts are seasonal the fertile mind sprouts ideas at times they turn arid but when rains kiss the parched mind a literary garden blooms.\nThe above is a tanka poem.\nTanka is a poetry form which originated in Japan more than 13 centuries ago. In its purest form, tanka poems are most commonly written as expressions of love, self-reflection, and gratitude. It contains five lines and 31 syllables in the form of 5-7-5-7-7.", "pred_label": "__label__POS", "pred_score_pos": 0.722662091255188}
{"content": "Abstract\nDuring development, cells adopt distinct metabolic strategies to support growth, produce energy, and meet the demands of a mature tissue. Some of these metabolic states maintain a constrained program of nutrient utilization, while others providing metabolic flexibility as a means to couple developmental progression with nutrient availability. Here we discuss our understanding of metabolic programs, and how they support specific aspects of animal development. During phases of rapid proliferation a subset of metabolic programs provide the building blocks to support growth. During differentiation, metabolic programs shift to support the unique demands of each tissue. Finally, we discuss how a model system, such as Drosophila egg development, can provide a versatile platform to discover novel mechanisms controlling programmed shift in metabolism.\nASJC Scopus subject areas Genetics Developmental Biology", "pred_label": "__label__POS", "pred_score_pos": 0.9919192790985107}
{"content": "Continuous Integration and Delivery is commonplace for software. Let’s benefit from the same principles and apply them to documentation as well: Keep it up to date, run automated tests, collaborate as teams, roll it to production seamlessly.\nI firmly believe that ecosystems can only evolve if they understand their users. The need to write documentation for software is universal, yet each project has different audiences for its documentation and unique constraints. Let’s find out what’s common, what methods and tools work, and where we need to improve!\nUpdate: The Continuous Documentation Camp is rebooting\nI planned for an un-conference, but planning was difficult due to the COVID-19 virus. The number of registered participants was too small. The camp is rebooting to find a new concept to attract more participants and to avoid an impact of the virus.\nAll tickets have been refunded. Follow me on Twitter to receive updates on a new concept once it is available.\nContact me if you want to help or share ideas how to make this concept work.", "pred_label": "__label__POS", "pred_score_pos": 0.5200070142745972}
{"content": "THIS EVENT HAS BEEN POSTPONED—WE WILL ANNOUNCE A NEW DATE SOON! (originally scheduled for 10 November) Overview\nIn commercial environments, there is often a lack of understanding of research ethics. As a result, navigating the world of ethics can often be stressful and challenging for commercial researchers. In this session, Nazima Kadir will:\nprovide a history of ethical research and its relevance to commercial researchers who interact with people explain the concept of informed consent and how to practice it throughout the research process provide an opportunity for participants to evaluate different situations that arise in commercial research and evaluate them using ethical research frameworks\nNazima's approach to ethical research is based on her experience conducting sensitive and long-term research among vulnerable populations, undergoing rigorous human subjects reviews, and using the ethical guidelines of the American Anthropological Association and the Market Research Society. She has conducted research with populations as varied as Asian domestic workers in Cyprus, victims of police conduct in New York City, squatters in Amsterdam, African immigrant mothers in London, and gig economy workers in Brazil.\nPresenter\nNazima Kadir is the principal of the October Anthropologist, a global anthropological consultancy specializing in anthropological research for a variety of purposes: from public art and education to innovation and design. She has a PhD in anthropology from Yale and has over 20 years of experience conducting and applying anthropological research. Her book\nThe Autonomous Life, published by Manchester University Press, was shortlisted for the BBC Ethnography award, and featured on Radio 4 and Wired magazine.", "pred_label": "__label__POS", "pred_score_pos": 0.6704229116439819}
{"content": "Islamic finance has not been immune from the woes faced by the broader financial markets. On the contrary, for the first time since Islamic finance has matured into a global phenomenon, it has confronted issues of default, insolvency and restructuring on a significant scale and, in some cases, on the global stage. The need of Dubai World, Kuwait’s The Investment Dar, and other Gulf based investment and real estate development firms, to restructure billions of dollars in financing has made headlines around the world. Shariah-compliant investments made in Western nations have also required restructuring, alongside their conventional counterparts, due to the economic downturn in these nations. These defaults have precipitated efforts on the part of borrowers and creditors to restructure financial liabilities, both in and out of bankruptcy.\nTo read the full article, click below.\nReprinted with permission from\nFinancier Worldwide Magazine.", "pred_label": "__label__POS", "pred_score_pos": 0.6520687341690063}
{"content": "The immunocytochemical and electrophoretic localisation of aflatoxin B1-binding proteins in isolated liver mitochondria. Abstract\nMitochondria perform functions which are central to the life of most eukaryotic cells. These organelles can be considered the ultimate energy power house of a living cell. The role of mitochondria in cancer phenotype remains a fertile area of research. Several carcinogens are known to enter the mitochondria, resulting in impaired functioning and altered structure. Aflatoxin BI (AFB1) a primary type I mycotoxin elaborated by Aspergillus flavus and Aspergillus parasiticus, is carcinogenic for a wide species range. The epoxide is capable of binding to nucleic acids and proteins, resulting in induced mutations, cellular toxicity, and eventually carcinogenesis. Approximately 250 000 deaths occur annually in both China and Africa due to patients presenting with Hepatocellular Carcinoma (HCC). The causative agents being AFB1-ingestion via contaminated foods and feeds, and the Hepatitis B Virus infection. The toxin has a multifaceted mode of attack, capable of being activated to a highly reactive and carcinogenic derivative, the AFB1-8,9-epoxide, via the cytochrome P450 enzyme system of the microsomes, endoplasmic reticulum and also the mitochondria. The epoxide is capable of binding to nucleic acids and proteins, resulting in the formation of covalent adducts. The repeated occurrence of gold labelled toxin within mitochondria from hepatomas of patients presenting with HCC suggested that these organelles were direct sites of toxin binding. Despite observations that mitochondria appear as direct and perhaps preferential targets for attack by AFB1, the actual in vivo immunolocalisation and characterisation of bound AFB1 within liver mitochondria has not been reported previously. In addition the role of AFB1-protein binding within mitochondria was investigated to determine the mode of action of the toxin, within the mitochondrial system. Liver sections from rats treated with a single lethal dose of AFB1, showed distinct ultrastructural abnormalities viz. large nuclei, increased heterochromatin, and swollen mitochondria. Immunocytochemistry revealed for the first time, the selective localisation of conjugated gold labelled toxin within the mitochondria. Toxin was found in the intracristal and peripheral spaces and frequently within the mitochondrial matrix. The mitochondria isolated from treated rats revealed significant alterations and damage to the mitochondrial membranes. The cristae were also markedly swollen with the associated clearing of the mitochondrial matrix. Western blot immunoassays revealed the presence of five AFB1-bound proteins (150kDa, 50kDa, 25kDa, 18kDa, 14kDa) in the inner mitochondrial fraction of isolated mitochondria. High pressure liquid chromatography also revealed that a significant proportion (84%) of an initial dose of toxin, was absorbed by mitochondrial protein. This study is the first to show the presence of specific mitochondrial proteins involved in toxin binding. In addition, the presence of toxin within the mitochondria and the specific binding to inner mitochondrial proteins suggest that the toxin specifically targets the electron transport chain and hence effects ATP production. This study conclusively indicates that mitochondria are direct targets for attack by AFB1 during experimental carcinogenesis. Mitochondria therefore play an important role in AFB1-mediated carcinogenesis.", "pred_label": "__label__POS", "pred_score_pos": 0.818544328212738}
{"content": "Despite a 69% rise since the March 23 lows of this year, and at the current price of around $670 per share, we believe\nSherwin-Williams stock (NYSE: SHW) has reached its near term potential based on its historical P/E multiples. The company, which is a global leader in the development, manufacture, and sale of coatings, paints, and related products, has seen its stock rally from $397 to $670 off the recent bottom compared to the S&P which moved around 50%. The stock is leading the overall markets, as investors are positive about the strong demand in the retail segment – architectural DIY paints, which was also evident from the 21% jump in U.S. retailing network sales in the second quarter. Further, the stock is up 15% from the level seen at the end of 2019.\nSherwin-Williams’ stock has surpassed the level it was at before the drop in February due to the coronavirus outbreak becoming a pandemic. This seems to make it fully valued as, in reality, demand and revenues will likely be lower this year than last year.\nSome of the rise over the last 2 years could be attributed to roughly 20% growth seen in Sherwin-Williams’ revenues from FY 2017 to FY 2019. However, the net income figure decined by 11% over the same period. This drop in net income could be attributed to the one-time income tax benefit in FY 2017 due to the enactment of the U.S Tax Act.\nWhile the company has seen steady revenue growth over FY 2017-19, its P/E multiple has also increased. We believe the stock is unlikely to see a significant upside after the recent rally and the potential weakness from a recession driven by the Covid outbreak. Our dashboard\nWhat Factors Drove 64% Change in Sherwin-Williams Stock Between FY 2017 And Now? has the underlying numbers.\nSherwin-Williams’ P/E multiple changed from around 22x in FY 2017 to close to 35x in FY 2019. While the company’s P/E is just below 40x now, there is a downside when the current P/E is compared to levels seen in the past years – P/E of about 35x at the end of FY 2019 and around 33x at the end of FY 2018.\nSo what’s the likely trigger and timing for the downside?\nSherwin-Williams is a global paint giant that deals in the development, manufacturing, distribution, and sale of paint, coatings, and related products to professional, industrial, commercial, and retail customers. The company has reported lower revenues in Q1 and Q2 on a year-on-year basis mainly due to lower demand in certain product ranges like performance coatings etc. Further, lockdown restrictions during March, April, and May also contributed to this drop due to the closing down of its store locations. On the other hand, sales have increased in the retail segment (architectural DIY paints for homes), as more and more people have taken on home projects. This was able to offset some of the negative impact of lower revenues in the other units. While the investors are positive about the stock due to growth in the retail segment, we believe that the revenues and earnings for FY 2020 are likely to remain lower than the previous year. This is expected to put pressure on the stock price.\nThe actual recovery and its timing hinge on the broader containment of the coronavirus spread. Our dashboard\nTrends In U.S. Covid-19 Cases provides an overview of how the pandemic has been spreading in the U.S. and contrasts with trends in Brazil and Russia. Following the Fed stimulus — which set a floor on fear — the market has been willing to “look through” the current weak period and take a longer-term view. With investors focusing their attention on 2021 results, the valuations vs historic valuations become important in finding value. Though market sentiment can be fickle, and evidence of an uptick in new cases could spook investors once again.\nWhat if you’re looking for a more balanced portfolio instead? Here’s a\nhigh quality portfolio to beat the market, with over 100% return since 2016, versus 55% for the S&P 500. Comprised of companies with strong revenue growth, healthy profits, lots of cash, and low risk, it has outperformed the broader market year after year, consistently.", "pred_label": "__label__POS", "pred_score_pos": 0.8412387371063232}
{"content": "by Patrick Taylor,\nPrincipal What are Feasibility/Site Selection Studies?\nAs a community grows and prospers, it may become more evident that a new or replacement airport is a necessary piece of critical transportation infrastructure. Airports, particularly general aviation airports, provide a connection to markets on a regional and national level. The FAA prescribes a process to developing a new or replacement airport. The first step to determining if a new or replacement airport is needed and can be supported is the\nAirport Feasibility Study. Should it be determined that the local economy can support an airport, then an appropriate location is identified through a Site Selection Study. Once a site is identified, a master plan of the site is developed, followed by an Environmental Assessment. Feasibility Study\nThe Feasibility Study typically begins with an economic inventory and market assessment of the region expected to support the airport. This will include an analysis of aviation demand factors, such as competing airports, and potential aviation services to be offered. The next element is a detailed market assessment which includes a forecast of aviation demand and a determination of the specific facility requirements, such as runway length. The financial feasibility analysis will include a construction cost estimate and a detailed analysis of funding sources, including potential federal/state grant assistance.\nSite Selection Study\nThe Site Selection Study will analyze numerous potential airport sites and identify a preferred alternative. With the abundant availability of geographic data, it is most common to filter various site selection factors through a\ngeographic information system (GIS). Factors to be considered will include existing terrain, proximity to the region being served, proximity to other area airports, access to surface transportation infrastructure, and proximity to utilities. Successful Implementation\nFirst and foremost, there must be local political support for a new or replacement airport. There must also be an open and transparent process that actively engages the community, especially those that may be impacted by the planned location of the airport. Agencies anticipated to financially participate (FAA, State Aviation) should be engaged early in the process. The FAA prescribed process for a new/replacement airport additionally requires an\nAirport Master Plan followed by an Environmental Assessment. All four studies are eligible for FAA funding with a 10 percent local matching share.", "pred_label": "__label__POS", "pred_score_pos": 0.6770102977752686}
{"content": "Abstract PURPOSE: We aimed to evaluate the ADNEX MR scoring system for the prediction of adnexal mass malignancy, using a simplified magnetic resonance imaging (MRI) protocol.\nMETHODS: In this prospective study, 200 patients with 237 adnexal masses underwent MRI between February 2014 and February 2016 and were followed until February 2017. Two radiologists calculated ADNEX MR scores using an MRI protocol with a simplified dynamic study, not a high temporal resolution study, as originally proposed. Sensitivity, specificity, positive and negative predictive values, likelihood ratios, and the area under the receiver operating characteristic curve were calculated (cutoff for malignancy, score ≥ 4). The reference standard was histopathologic diagnosis or imaging findings during >12 months of follow-up.\nRESULTS: Of 237 lesions, 79 (33.3%) were malignant. The ADNEX MR scoring system, using a simplified MRI protocol, showed 94.9% (95% confidence interval [CI], 87.5%–98.6%) sensitivity and 97.5% (95% CI, 93.6%–99.3%) specificity in malignancy prediction; it was thus highly accurate, like the original system. The level of interobserver agreement on simplified scoring was high (κ = 0.91).\nCONCLUSION: In a tertiary cancer center, the ADNEX MR scoring system, even based on a simplified MRI protocol, performed well in the prediction of malignant adnexal masses. This scoring system may enable the standardization of MRI reporting on adnexal masses, thereby improving communication between radiologists and gynecologists.\nYou may cite this article as: Pereira PN, Sarian LO, Yoshida A, et al. Accuracy of the ADNEX MR scoring system based on a simplified MRI protocol for the assessment of adnexal masses. Diagn Interv Radiol 2018; 24:63–71.", "pred_label": "__label__POS", "pred_score_pos": 0.7009619474411011}
{"content": "In the game, the player acts as the head of the World Pandemic\nControl during the outbreak of an unknown flu. As the game progresses, the player must take actions, such as dispatching research teams, dispensing medication and face masks, and closing schools and airports, in an attempt to control and ultimately defeat the virus. As the pandemic intensifies, the player is given information about the history and science of epidemics through a series of newspaper articles and videos. Eventually, if the player is successful, the game ends with a count of the number of people infected and killed over the pandemic’s life span, and the money spent containing the virus.\nI think the game succeeds in presenting players with a lot of\ninformation through the multimedia featured in the game, and by including hints in it, giving players incentive to absorb it. Furthermore, it nicely illustrates the dangers of our highly connected world: there’s nothing more jarring than fighting a virus raging in Central and North America only to glance at Europe and find the epidemic exploding half way across the globe. However, the game does suffer from a few common pitfalls, and going over them might shed some light on some of the challenges with using games for education.", "pred_label": "__label__POS", "pred_score_pos": 0.5058674216270447}
{"content": "Paternity is defined as the legal relationship between a father and his children, and the rights and responsibilities that come along with that relationship. Fathers who are or were married to the mother of their child do not typically need to establish paternity, since the legal presumption is that a mother's husband or ex-husband (within a biologically appropriate time-frame) is the father.\nUnmarried fathers, however, must proactively establish their paternity - or the mother may seek to do so. Unless both parents agree on who is the child's father and are willing to submit a signed acknowledgment, it is likely you will need to establish paternity in court. If you are a parent seeking to have the paternity of your child established for legal reasons, an experienced paternity lawyer in Illinois can help. Our firm's paternity attorneys have experience representing both mothers and fathers in paternity cases.\n...\nRights and Responsibilities of Legal Fatherhood", "pred_label": "__label__POS", "pred_score_pos": 0.9895749688148499}
{"content": "a large national survey has found.\n“Over the past decade, there has been an increase in the use of cannabis among cigarette smokers and prevalence of cigarettes and cannabis co-use, suggesting that the negative consequences of cigarette–cannabis co-use may also become more prevalent over time,” wrote Andrea H. Weinberger, PhD, of Yeshiva University, New York, and colleagues. They noted that the prevalence of cigarette smoking is nearly three times higher among persons who use cannabis and have cannabis use disorders relative to those who do not.\nThe 2019 National Survey of Drug Use and Healththat 15.9% of Americans aged 12 years or older used cannabis in the past year. This number has been rising throughout the 2000s.\nIn that same report, cannabis use disorder (or marijuana use disorder) was defined as when an individual experiences clinically significant impairment caused by the recurrent use of marijuana, including health problems, persistent or increasing use, and failure to meet major responsibilities at work, school, or home. The report stated that approximately 1.6% of Americans aged 12 or older in 2018 had marijuana use disorder.\nIn the study published in, the researchers used the National Survey on Drug Use and Health data to analyze cigarette smoking quit ratios among U.S. adults with and without cannabis use and cannabis use disorders. “Quit ratio was calculated as the proportion of former smokers among lifetime smokers and is considered a measure of total cessation in a population,” the researchers said.\nIn 2016, the quit ratios for adults with a history of cannabis use or cannabis use disorders were 23% and 15%, respectively, compared with 51% and 48%, respectively, in those with no cannabis use or cannabis use disorders.\nOverall, quit ratios did not change significantly from 2002 to 2016 for individuals with cannabis use disorders after controlling for multiple demographic factors and other substance use disorders. However, during the same time period, quit ratios showed a nonlinear increase in cannabis users, nonusers, and individuals without cannabis use disorders.\nThe study findings were limited by several factors including the inability to generalize results to youth or individuals living outside the United States, the use of DSM-IV criteria to identify cannabis use disorder, the use of self-reports, and the inability to examine the timing of cannabis use as related to attempts to quit smoking, the researchers noted. However, the results highlight the need to consider offering smoking cessation treatment to individuals being treated for cannabis use disorders, and to include cannabis users in smoking cessation programs, the researchers noted.\n“Based on our results, both public health and clinical efforts to improve cigarette quit outcomes may benefit from including those with any cannabis use,” they said. More research is needed to determine whether trends in the quit ratio change over time for cannabis users or those with cannabis use disorder, they added.\nThe study was funded by the National Institute on Drug Abuse. The researchers had no financial conflicts to disclose.\nSOURCE: Weinberger AH et al. Tob Control. 2020;29(1):74-80. .", "pred_label": "__label__POS", "pred_score_pos": 0.9255441427230835}
{"content": "Windscreen repair services are now growing quickly in Leicester. You can repair your windscreen with much ease with a lifetime guarantee. Experts in windscreen repair will never let you down as these are produced from high-quality basic materials.\nIt is crucial that you do it the ideal method when it comes to windscreen repair. You will run the risk of getting your windscreen damaged completely during a mishap. This may also cost you your life, as well as your family’s.\nWindshield fractures are amongst the most typical issues dealt with by provider of the best Windscreen repairs in Leicester. Some windscreens do not reveal indications of a fracture or chip right away.\nWith time, the fracture might extend throughout the entire screen and change the driver’s view. Below are a few of the most typical reasons for windscreen chips and fractures:\n1. Small Stones — Small stones, which are tossed on the windscreen, are one of the significant causes of windscreen fractures. But this problem can be easily solved. As soon as a car has an issue with this crucial part of its body, take a look at any new windscreens repair businesses to ensure that your car stays in good shape.\n2. Direct Sunlight — Direct sunshine might not be a significant reason for windscreen fractures, in locations with low-temperature levels. In case you experience extreme heat, it might warp the glass shape or fracture the windscreen. To avoid your car from such, set up a sunshade in your car. This will help you avoid direct sunshine from harming your windscreen. You must also park the car in a shady area if you live in a humid location.\n3. Roadway Debris — Roadway debris is also among the significant reasons for windscreens fractures. This primarily takes place throughout roadway building and construction. Sometimes, a loose debris on the roadway may land on your windshield. Also, trucks that pass by you drop little stones. These stones are most likely to bounce from the ground, striking the screen of the car behind. To prevent this from occurring, minimize the speed of your car, specifically when another car is surpassing.\n4. Structural Weakness — In case of an accident, a car deflects the airbags on the passenger’s side and support the roofing system. They are set up using an adhesive, they can break in case of a structural pressure, specifically if the pressure is applied at the windshields edges.\nWindshields are a vital part of a car’s security system. Driving a car with a broken or chipped windscreens is a terrific risk. Not all individuals that drive are watchful and animals can also leap onto the asphalt anytime without a sign. For this factor, it is crucial for a driver to have excellent vision. This is just possible with a great windshield. It doesn’t matter if the damage is small or barely noticeable. As soon as you see a chip, have a look at any windscreen repair business for instant repair. If you’re in Leicester, one of the must-visit repair centres is http://www.allscreens-nationwide.co.uk. a", "pred_label": "__label__POS", "pred_score_pos": 0.5935931205749512}
{"content": "The mediation of disputes by community leaders in China has deep historical roots and has long been among the responsibilities of neighbourhoods and villages. While most research on the topic has looked at cities, mediation is in fact more common in the countryside. This paper draws on a survey conducted in 2002 (n=2,164) and repeated in 2010 (n=2,659), covering 23 villages in five provinces, which provides detailed data on conflict from disputants themselves. We examine the evolution of this much-debated mode of conflict resolution and assess its prevalence and effectiveness relative to alternatives. We find that, even as overall rates of disputing declined, seeking intervention by village authorities remained as common a response to disputes in 2010 as it was eight years prior. The paper thus sheds light on a primary means through which the party-state has tried to maintain stability, tamp down strife, and assert its primacy at the community level.", "pred_label": "__label__POS", "pred_score_pos": 0.6040377616882324}
{"content": "India suffers from twin challenge of high prevalence of communicable disease and risk of premature deaths from non-communicable diseases (NCDs). The overall healthcare spend in India is 4.2% of GDP (2018), lowest amongst BRICS counties, while global health care expenditure average amounts to approximately 10.2%. This is further exacerbated as the Government healthcare expenditure has largely been stagnant during last 10 years (~1.2% of GDP in 2018)1 . This has resulted into high out of pocket (OOP) spend on healthcare (65%).\nThis report on Driving Health Insurance Penetration in India – Covering the Missing Middle - highlights the existing issues in healthcare insurance penetration in India and presents suggestions to address them.", "pred_label": "__label__POS", "pred_score_pos": 0.9044929146766663}
{"content": "Norovirus is a major cause of acute gastroenteritis, with at least 49 different norovirus genotypes. GII.4 genotype is responsible for the majority of norovirus epidemic outbreaks. The genotypes associated with medically-attended sporadic acute gastroenteritis are less clear.\nZaid Haddadin, MD, Einas Batarseh, MD, and colleagues compared the clinical characteristics and distribution of norovirus genotypes in children who sought medical care for acute gastroenteritis in three clinical settings (outpatient, emergency department, inpatient) over three years.\nIn 2,885 children, norovirus was detected in 22% of stool samples. Nearly 90% of the norovirus-positive samples were GII-positive, and GII.4 viruses were detected in 51% of the genotyped GII-positive samples. Seasonal variations were noted among different genotypes, and children with GII.4 infections were younger and had more severe symptoms requiring more medical care compared to children with non-GII.4 infections.\nThe findings, reported in Clinical Infectious Diseases, highlight the importance of continuous norovirus surveillance and could guide strain selection for candidate norovirus vaccines.", "pred_label": "__label__POS", "pred_score_pos": 0.715064525604248}
{"content": "Bibtek download is not availble in the pre-proceeding\nEkin Dogus Cubuk, Barret Zoph, Jon Shlens, Quoc Le\n<p>Recent work on automated data augmentation strategies has led to state-of-the-art results in image classification and object detection. An obstacle to a large-scale adoption of these methods is that they require a separate and expensive search phase. A common way to overcome the expense of the search phase was to use a smaller proxy task. However, it was not clear if the optimized hyperparameters found on the proxy task are also optimal for the actual task. In this work, we rethink the process of designing automated data augmentation strategies. We find that while previous work required searching for many augmentation parameters (e.g. magnitude and probability) independently for each augmentation operation, it is sufficient to only search for a single parameter that jointly controls all operations. Hence, we propose a search space that is vastly smaller (e.g. from 10^32 to 10^2 potential candidates). The smaller search space significantly reduces the computational expense of automated data augmentation and permits the removal of a separate proxy task. Despite the simplifications, our method achieves state-of-the-art performance on CIFAR-10, SVHN, and ImageNet. On EfficientNet-B7, we achieve 84.7% accuracy, a 1.0% increase over baseline augmentation and a 0.4% improvement over AutoAugment on the ImageNet dataset. On object detection, the same method used for classification leads to 1.0-1.3% improvement over the baseline augmentation method on COCO. Code is available online.</p>", "pred_label": "__label__POS", "pred_score_pos": 0.8450397253036499}
{"content": "Blog\nHurricanes, typhoons and cyclonic storms are all forms of tropical cyclones, creating havoc and causing damage with high winds, rain and storm surge in low-lying regions.\nThunderstorms, ranging from mild to severe, are the most common weather formation, producing heavy rainfall, hail, high winds, flash floods, and damaging tornadoes.\nThe National Weather Service explores why people ignore warnings of approaching severe weather. Answers are vital to those that utilize NWS forecasts including mariners.\nHurricane watches and warnings are issued to warn residents of danger and damages that could occur with a hurricane. Understand the warnings and prepare to minimize risk.", "pred_label": "__label__POS", "pred_score_pos": 0.9966975450515747}
{"content": "10/28/2020\nBy Jessica Van Mulligen\nCost of legal representation and long wait times for a court date are common barriers. A less commonly discussed barrier is the physical layout of the law courts. Physical layout can include signage, seating, the availability of workspaces, or areas that offer privacy.\nLaw is a service profession[1], and the courts are key for legal service delivery. If the way legal services are administered is not meeting the needs of litigants, something needs to change. This need is intensified with the increasing prevalence of self-represented litigants within the legal system.[2] So, how do we ensure litigants using the courts are empowered to the greatest extent? Enter, human-centered design.\nHuman-centered design is a methodology for creating user-focused innovations. Human-centered design “judges a product, service, or system by what the experience of its audience is… [and that] to improve the functionality and experience of a given system, the needs and preferences of the user should be the guide.”[3] Human-centered design targets litigants, not lawyers.\nFoundational to a human-centered design project is collaboration with skilled professionals. Alberta Access to Justice Week presents an opportunity to collectively strategize how law courts can be reconfigured to be more user-friendly. With decreased traffic in the courts due to COVID-19, now is the ideal time to undertake these collaborative projects.\nInitiating this collaboration, I offer insight into my observations, informed by human-centered design, from attending the Edmonton Law Courts in 2019. As I navigated the courts, I asked myself two questions: Where are there gaps? What else is possible? I observed several areas to address, but in this post, I highlight the signage at the law courts.\nAfter completing a security check, litigants reach an airport-like information board with a list of matters being heard that day (Figure 1). While matters are organized alphabetically and assigned a colour based on the relevant level of court, this colour-coding is not carried over into other official signage. Additionally, the official signage is posted in high-traffic areas like elevator banks (Figure 2), making it difficult to review the information.\nSignage for legal aid services is particularly confusing because of its inconsistency. For example, Civil Claims Duty Counsel litigants must walk right up to the check-in table to locate the service (Figure 3). Further deficiencies in legal aid service signage include: inconsistent posting locations, limited information provided, obscure sign formats and signage in non-prominent areas (Figures 3, 4, 5). It is troubling that key services to assist litigants are not easily identified at the courts.[4]\nHuman-centered design tackles access to justice issues by ensuring innovations serve litigants who are unfamiliar with navigating their legal journey - innovations accessible to this group will also serve the broader public.[5] With a human-centered approach, litigants can handle their legal issues with greater confidence, knowing that spaces they encounter were designed with, and for, them.\nCompleting this research, I did not consider that a pandemic would so quickly reshape how in-person services are provided. I leave it in your hands, as the reader, to continue reimagining the usability of law courts, perhaps with greater focus on the usability of legal services online.\nJessica Van Mulligen graduated from the University of Alberta, Faculty of Law in 2020. She is articling at the Edmonton office of Bishop McKenzie. This post is based on a research paper that she completed for a class in access to justice taught by Professor Anna Lund.\n-------------------------------------------------------------\n[1] Margaret Hagan, “Design Thinking and Law: A Perfect Match”,\nLawPractice Today (Innovation Issue) (January 2014), online <http://www.courts.ca.gov/documents/BTB24-Precon1G-2.pdf> at 3 [Hagan, “Design Thinking”].\n[2] See generally Julie Macfarlane, Final Report, “The National Self-Represented Litigants Project: Identifying and Meeting the Needs of Self-Represented Litigants” (May 2013) (there is an SRL explosion in Canada).\n[3] Hagan, “Human-Centered Design Approach”,\nsupra note 5 at 202.\n[4] My quick suggestions to increase usability: colour-coded signs to correspond with the colouring system that already exists on the information screens and digitally map the interior of the Edmonton Law Courts.\n[5] Shannon Salter, “Online Dispute Resolution and Justice System Integration: British Columbia’s Civil Resolution Tribunal” (2017) 34 Windsor YB Access Just 112 at 124.", "pred_label": "__label__POS", "pred_score_pos": 0.8500497341156006}
{"content": "Market participants in the securities industry are contemplating various applications of the blockchain. Many of these participants have focused on discrete applications within the broader equity, debt and derivative markets. They focus on separate applications and devising limited-scale experiments related to the implementation of DLT. This is because, they seek to avoid the potential risks associated with more wholesale changes. Moreover, many of them have also focused on sectors they believe present significant inefficiencies. These inefficiencies are concerning their clearing infrastructure, operational processes or administrative functions. This is primarily driven by the view that focusing on areas with existing high levels of inefficiencies provides greater opportunities for demonstrating meaningful enhancements.\nHow does it work?\nThe administrative process of tracking the transfer of private company shares and maintaining capitalization tables may be manual, expensive and subject to errors. It may expose private issuers to regulatory risks. In light of these concerns, some market participants are considering DLT-based applications. This is to implement a system to track trading and ownership of private company shares. For example, in late 2015, one market participant launched a DLT-based platform for the issuance and trading of private company shares. This platform aims to provide private business issues with real-time transparency into the records or trading activity of its shares and shareholders of record.\nSome market participants are also exploring issuance and trading public company stock on a DLT-based platform. For example, one public company issuer recently issued a new class of digital shares directly on a proprietary DLT network such that the trading of shares happens on the platform with a same-day settlement. Similarly, some vendors are developing DLT-based trading systems for publicly traded securities. DLT has the potential to affect various aspects of the securities market. This includes market efficiency, transparency, post-trade processes and operational risk.", "pred_label": "__label__POS", "pred_score_pos": 0.9981808662414551}
{"content": "Review | Open Access\nA Lazarescu, \"New Diagnostic Techniques for Esophageal Disorders\",\nCanadian Journal of Gastroenterology and Hepatology, vol. 22, Article ID 671434, 6 pages, 2008. https://doi.org/10.1155/2008/671434 New Diagnostic Techniques for Esophageal Disorders Abstract\nEsophageal disorders are common in the general population and can be associated with significant morbidity. Several new diagnostic techniques for esophageal disorders have become available in recent years. These include capsule pH-metry, high-resolution manometry, impedance combined with either pH-metry or manometry, and high-frequency ultrasound. Capsule pH-metry is useful in children and in patients who cannot tolerate the conventional pH-metry catheter. It has the advantage of not interfering with a patient’s usual meals and activities during the 24 h study. High-resolution manometery is easier to perform and interpret than conventional manometry. This has led to improved diagnosis of various esophageal motility disorders. Impedance measures the movement of liquid and gas in the esophagus. When combined with pH-metry, impedance can confirm that retrograde bolus movement (ie, reflux) is occurring while simultaneously measuring changes in pH levels. It has also highlighted the importance of weakly acidic reflux in patients who do not respond to proton pump inhibitors. Weakly acidic reflux cannot be diagnosed with pH-metry alone. Impedance combined with manometry can determine whether a manometric abnormality leads to abnormal bolus clearance. In the past, this was performed with fluoroscopy, yet impedance is equally effective and does not carry the risk of increased radiation exposure. High-frequency ultrasound is currently a research tool to image the esophageal wall, particulary the two muscle layers, in real time during swallows and at rest. It has broadened our understanding of the pathophysiology of esophageal motility disorders.\nCopyright\nCopyright © 2008 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.", "pred_label": "__label__POS", "pred_score_pos": 0.5317598581314087}
{"content": "Motor vehicle accidents can happen at any time of the day or night and for a variety of different reasons. Despite this, law enforcement officers in Virginia and across the country may be quick to make assumptions about the cause of accidents that happen at a certain time of day. For example, they may automatically suspect that drunk driving is a factor in accidents that happen during the early morning hours.\nIn fact, a man was recently arrested for his alleged role in an accident that reportedly resulted in the death of a tractor-trailer driver. The incident is said to have occurred during the early morning hours of a day in late February. According to reports, a 37-year-old driver was headed south on a Virginia interstate when his vehicle veered over the median into oncoming traffic.\nReports indicate that his vehicle struck a tractor-trailer driven by a 53-year-old man. The latter is then believed to have lost control of the truck, allegedly resulting in the vehicle striking a guardrail and turning over. The truck driver had to be extricated but died.\nThe other driver was taken into police custody on suspicion of drunk driving in the Virginia crash. Despite his arrest, it is unclear what evidence supports the accusations against him or what his blood alcohol content was at the time of the collision. While an accident such as this is always a tragedy, there must be sufficient evidence to prove that a person is guilty beyond a reasonable doubt to convict them. Most people facing criminal charges want an experienced attorney on their side as they carefully weigh their options and determine what course of action is most appropriate for their individual situation.", "pred_label": "__label__POS", "pred_score_pos": 0.7740013599395752}
{"content": "PlasticsEurope and supporting member companies of Operation Clean Sweep (OCS) – an international programme to help prevent resin loss from getting into the marine environment – have presented the latest report on the ongoing activities regarding marine protection.\nIn its “operation clean sweep report 2017”, PlasticsEurope detailed measures taken by members to prevent pellet loss, including moves such as modifying equipment for better containment, training employees and involving their entire value chain, among others.\nA Zero Pellet Loss (ZPL) initiative was initially launched in 2013 by PlasticsEurope to raise awareness among employees at manufacturing plants on how to manage pellets and other particles at each step of the production and supply chain.\nZPL was then integrated on a pan-European base, into the global OCS programme in 2015.\nPlasticsEurope is targeting 100%-member engagement in the OCS programme for year-end 2017 and the report encourages other industry associations, policy-makers, NGOs and the general public to join this initiative to help achieve the goal of ‘zero pellet loss'.\nAccording to PlasticsEurope more than half of its members have signed the OCS pledge and are implementing different measures within their companies.", "pred_label": "__label__POS", "pred_score_pos": 0.664126992225647}
{"content": "Qing Ye\n02-05-2018\n11:00AM-12:00PM\n2206A Student Center\nDiabetes Self-management (DSM) applications (apps) have been designed to improve knowledge of diabetes and self-management behaviors. However, few studies have systematically examined if diabetes apps followed the American Association of Diabetes Educators (AADE) Self-Care Behaviors\nTM guidelines. The purpose of this study was to compare the features of current DSM apps to the AADE7 TM guidelines. In two major app stores, we used three search terms to capture a wide range of diabetes apps. Apps were excluded based on five exclusion criteria. A multidisciplinary team analyzed and classified the features of each app based on the AADE7 TM. We conducted interviews with six diabetes physicians and educators for their opinions on the distribution of the features of DSM apps. Out of 1,050 apps retrieved, 173 apps were identified as eligible during November 2015 and 137 apps during December 2017. We found an unbalanced DSM app development trend based on AADE7 TM guidelines. Future diabetes apps should attempt to incorporate features under evidence-based guidelines such as AADE7 TM to better support the self-management behavior changes of people with diabetes.", "pred_label": "__label__POS", "pred_score_pos": 0.6032695770263672}
{"content": "Meanwhile, you could also be at risk of coronavirus if you develop a new, continuous cough, or shortness of breath.\nYou’re more likely to be infected with COVID-19 if you develop at least two other symptoms, it added.\nThese include a high fever, the chills, muscle pain, headaches, and a sore throat.\nSome patients have also reported losing their sense of smell and taste.", "pred_label": "__label__POS", "pred_score_pos": 0.7609327435493469}
{"content": "Building upon the previous subject (Research Thesis Capstone – Part 1), this subject provides opportunities to extend, deepen and apply knowledge, skills and attributes, in the context of a research project.\nThis subject enables students to engage in the implementation, analysis and communication of a research project that demonstrates their advanced theoretical knowledge and critical reflection skills. It provides the opportunity for integration of their prior learning from the course, and demonstration of their advanced practice, focusing on an area of interest. During this project, students will have the unique opportunity to be closely trained and supervised by leading experts in oncology. It will reinforce their abilities to evaluate existing research, utilise appropriate methodological techniques in cancer research and to critically analyse and reflect on data.\nSubject type Subject code Fee Term Accredited MEDI90099 Assessed: $3,460 Available in 2020", "pred_label": "__label__POS", "pred_score_pos": 0.7131046056747437}
{"content": "Abstract\nAutophagy is a conserved eukaryotic process of protein and organelle self-degradation within the vacuole/lysosome. Autophagy is characterized by the formation of an autophagosome, for which Vps34-dervied phosphatidylinositol 3-phosphate (PI3P) is essential. In yeast, Vps34 forms two distinct protein complexes: complex I, which functions in autophagy, and complex II, which is involved in protein sorting to the vacuole. Here we identify and characterize Atg38 as a stably associated subunit of complex I. In atg38Delta cells, autophagic activity was significantly reduced and PI3-kinase complex I dissociated into the Vps15-Vps34 and Atg14-Vps30 subcomplexes. We find that Atg38 physically interacted with Atg14 and Vps34 via its N terminus. Further biochemical analyses revealed that Atg38 homodimerizes through its C terminus and that this homodimer formation is indispensable for the integrity of complex I. These data suggest that the homodimer of Atg38 functions as a physical linkage between the Vps15-Vps34 and Atg14-Vps30 subcomplexes to facilitate complex I formation.", "pred_label": "__label__POS", "pred_score_pos": 0.9935215711593628}
{"content": "No one is a stranger to the notion of security. We protect our homes and physical assets with locks and cameras and are vigilant when we encounter abnormal behavior. But for some reason, the data entrusted to us is not always given the same type of protection. Your data has become a prime target for cybercriminals which is manifested in the form of ransomware attacks. Attacks which are becoming increasingly prevalent. Your data cannot be secured simply by restricting access. The whole point is to make data usable and available for people who need to use it, contribute to it, and manage it. The key to protecting content from ransomware is to understand how it infiltrates files. To be effective, all attackers need is access to files, and this can be achieved through rudimentary tactics. But with purposeful, automated analysis and alerting, ransomware attempts can be quickly detected, shut down, and remediated.\nRansomware and the damage done Ransomware can be spread through phishing emails that contain malicious attachments. Attackers can also use social engineering to gain access to account credentials, and from there, it is easy to plant ransomware anywhere that account has access. The most common form of ransomware is crypto ransomware, which is a malware variant that encrypts files. Once your files are encrypted, a ransom message will appear onscreen demanding payment, typically in the form of Bitcoin or another untraceable cryptocurrency. The reality is that attackers often successfully extort their victims. And these financial successes have led to a rise of ransomware attacks and variants. In 2013, destructive and lucrative ransomware variants were introduced, including Xorist, CryptorBit, and CryptoLocker. Some variants encrypt not just the files on the infected device, but also the contents of shared or networked drives. In early 2016, a destructive ransomware variant, Locky, was observed infecting computers belonging to healthcare facilities and hospitals in the United States, New Zealand, and Germany. It propagates through spam emails that include malicious Microsoft Office documents or compressed attachments (e.g., .rar, .zip). Once opened, the malicious attachments run macros or JavaScript files and download and install the Ransomware.", "pred_label": "__label__POS", "pred_score_pos": 0.9736735820770264}
{"content": "What Will it Take for Corporates to Prepare Their Global Payments Processes for the Future?Luc Belpaire, Director of Product – Payments, FISCorporations are missing out on leveraging transformative technology, such as a payment factory or bank integration solution due to a lack on incentive around modernising their treasury operations.\nWhat Will it Take for Corporates to Prepare Their Global Payments Processes for the Future?\nBy Luc Belpaire, Director of Product – Payments, FIS\nFor the sixth year running, FIS has surveyed corporate treasury and finance professionals globally – and once again, many departments are battling the same challenges as they faced in 2014. So, what will finally prompt them to modernise their operations for the future?\nOf the corporations surveyed, 84% have already centralised their payments. However, most companies are still working in extremely complex payments and bank connectivity environments. Almost half (48%) are managing more than 100 bank accounts and 19% work with at least 11 banks. This explains why so many corporations are still dealing with fraud risk, high costs, little control and a lack of visibility into cash.\nNotably, not many have taken the next step towards making their payments future-ready by implementing a payment factory solution. According to the report, only 10% rely on a payment factory to originate and deliver payments to banks.\nWhat opportunities are corporations missing?\nCorporations are missing out on leveraging transformative technology, such as a payment factory or bank integration solution that can help them centralise and standardise their payments processes.\nOf the respondents, the 79% which have implemented a payment factory have achieved payback within or under two years, and 67% achieved a return on investment (ROI) of more than $100,000, with 15% achieving an ROI of more than $1m.\nA payment factory performs these functions:\nConsolidates data feeds from multiple payment systems such as accounts payable (AP) or enterprise resource planning (ERP) into a single view of payments\nAutomates and assigns workflows for the payments processes across the entire organisation, from AP to HR to treasury\nPuts controls in place so payments don’t leave the organisation due to human errors or fraud\nConverts payment messages into formats that the banks require\nConnects to global banking networks such as SWIFT to help streamline connections to the multiple banks with which a corporation deals\nTakes advantage of the latest trends around real-time payments and other services that banking application programming interfaces (APIs) and SWIFT gpi have to offer\nActs as an in-house bank, helping reduce banking fees\nLook for these eight returns on investment (ROIs) when building a business case for a payment factory:\n1. Improved control and compliance A payment factory centralises and standardises payment processes. The entire payment chain is secure through data and role segregation, audit history and flexible signing rules. That means human errors and fraud can be avoided, tangibly improving security and compliance.\n2. Simplified integrations and workflows A payment factory enables the establishment of an in-house bank for subsidiaries. By executing all business-unit payments, the in-house bank gives enterprise-wide visibility and control. It can also act as the interface between a company and the financial markets.\n3. Reduced payment fraud By enhancing workflows with internal and external screening, a payment factory helps a business utilise blacklists, whitelists and fraud listings and achieve compliance across territories. Meanwhile, dashboards provide real-time insights into transaction status and exceptions.\n4. Greater visibility and insights Centralised accounts and cash flows give better visibility of cash, while intuitive interfaces make payments visible to cash positioning. Validation of bank statements offers control over payment flows. And intraday reporting enables a business to update cash positions regularly and spot unexpected incoming funding.\n5. Centralisation and automation A payment factory standardises processes with best-practice workflows across regions, entities, banks and payment types, increasing productivity and economies of scale. Inefficiencies can also be eliminated through automation because there is no need for multiple approvals in multiple systems. Finally, rationalising infrastructure can tangibly simplify IT and save administrative costs.\n6. Increased productivity As a company moves from multiple eBanking systems to a single hub, usability and user management are both improved. The time and cost of documentation and employee training can also be avoided. And by integrating enterprise resource management (ERP) and treasury systems, company growth can be supported while maintaining headcount.\n7. Lowered costs Bank-agnostic connectivity such as SWIFT reduces bank dependence and improves a company’s negotiating position. That can mean lower transaction fees and a higher funding credit line. What’s more, increased straight-through processing helps reduce bank repair fees for manual errors or missing data.\n8. Flexibility and real-time readiness Finally, a payment factory offers the agility to fine-tune processes and respond to new market requirements – such as real-time payments – without changing back-end systems. Similarly, changes can be implemented once without having to individually address back-office systems such as ERPs.", "pred_label": "__label__POS", "pred_score_pos": 0.5628954172134399}
{"content": "On November 28, 2018, the United States government announced the investment of $100 million, through PEPFAR, to address key gaps toward achieving HIV epidemic control and ensuring justice for children, including by leveraging the unique capacities and compassion of faith-based organizations and communities.\nThe Faith and Community Initiative seeks to:\nEngage communities of faith to reach men and children with testing and services, understand the epidemic, and raise community awareness through:\nFaith community structures; and\nExisting and additional FBO partners.\nStrengthen justice for children through:\nCommunity leaders (e.g., faith, traditional, school , civic);\nFaith & traditional organizations/structures; and\nJustice sector, and those who work with the Justice sector.", "pred_label": "__label__POS", "pred_score_pos": 0.9375244975090027}
{"content": "Securing IoT: Facilities Managers Play a Crucial Role\nSecuring the Internet of Things is a mandate that extends beyond the IT department, according to recent research from Urgent Technology. The organization’s facilities manager must be part of the conversation, according to the UK-based facilities management and asset management software firm. Today’s smart buildings are equipped with a range of IoT devices which automate much of the facility management processes, including lighting, heating, ventilation and air conditioning (HVAC), as well as lifts, escalators and security. As building management systems evolve into Internet-enabled building automation systems, they are much more susceptible to possible cyberthreats. A technology that enables users to control all the elements of a building, which includes security equipment such as CCTV (closed-circuit television) and door locks, is also more vulnerable to a cyberattack.\nTo address those cybersecurity risks that may affect their organizations, facilities managers first need to acknowledge they have a crucial role to play, according to Paul Djuric, CEO of Urgent Technology. Djuric shared his views and advice on the evolving role of the facilities manager in securing IoT deployments in this Q&A.\nWhy did you decide to examine the role of the facilities manager in cybersecurity? Djuric: Hackers are no longer going through an organization’s main IT systems. Instead they’re increasingly targeting property and facilities-related devices, which are connected to the internet, such as the building management system or desk sensors. The trend toward the utilization of the Internet of Things and connected devices in properties means that cyber-hacking is no longer the sole concern of the IT department. Can you share some advice on how facilities managers can gain a seat at the table for cybersecurity discussions? Djuric: Facilities managers who are concerned that their systems are vulnerable should begin the cybersecurity process by lobbying those who are responsible for the safeguarding of information to commission a data assessment. This will help an organization identify what critical information is stored, processed or transmitted, establish why the data might be an attractive target, and establish any regulatory compliance it must adhere to.\nOnce the value of data is understood, facilities managers should encourage the same parties to commission a formal risk assessment to identify the possibilities of reducing any unnecessary storage and processing. They should assess the likelihood and impact of an attack. They should formally identify what an appropriate security baseline should be and establish the extent of any gaps between the existing and target positions. They should conduct an efficient data risk assessment, and carry out both internal and external penetration tests on the network.\nFrom the perspective of securing IoT technologies, what would you say is the main takeaway from your firm’s research? Djuric: Facilities managers and their organizations face significant challenges in the future in combating the cyberthreats posed by the convergence of physical assets within a building with data. This is why a wide-ranging and proactive approach should be taken to ensure that the facilities manager can reap the undoubted benefits of workplace digitization, while ensuring that facilities are not open to undue risks. In the future, facilities management and IT must always remain alert to the latest cyberthreats, and must work together with their software supply chain to help reduce the likelihood of data breaches.", "pred_label": "__label__POS", "pred_score_pos": 0.6247780323028564}
{"content": "Mexico LED Lighting Market - Growth, Trends, Forecast (2020-2025) The Mexican LED lighting market is expected to witness a CAGR of 17.1% during the forecast period (20202025). In the current market state, LEDs have gained a mainstream in the lightings market. Key factors behind this are the continuous declining LED prices in the country coupled with favorable government initiatives. The National Public Lighting Program to replace traditional lightings with LED aimed at sustainable use of energy.The National Public Lighting Program in support from CONUEE, and the Federal Electricity Commission for guidance on implementation, verification, and financing of efficient lighting projects. According to the World Bank, Over 2.6 million highefficient light bulbs were sold to the residential customers for a subsidized cost of 60% in two cities (Guadalajara and Monterrey) as part of the pilot project demonstration for efficient LED lighting. This project ILUMEX has surpassed its physical targets and successfully demonstrated the feasibility of reducing both greenhouse gas emission and reduction in electricity consumption. Nevertheless, due to the availability of lowcost materials and a recovering economy, global players are setting up their manufacturing facilities in the region. For instance, in June 2019, a USD 1 billion plant in the State of San Luis Potosi, Mexico, was unveiled, which will be BMW’s second in the Americas when production starts in early 2021. However, the market has been affected by the recent outbreak of COVID 19, and companies have been forced to restructure their strategies to deal with the ongoing pandemic. Companies, like Signify, were the worst hit due to this pandemic. Signify in February 2020 had planned to upgrade their solar connected street light to toggle between solar and grid power by using Philips Combo Charge Controller. But the company has gone into financial crunch due to the COVID outbreak, the company in March 2020 had announced a 20 percent pay cut of all their employees. Key Market Trends Increasing Demand for Outdoor Lighting Due to Smart Development Initiatives to Drive the Market Growth In Mexico, even though the LED penetration is low for the residential end user, the government is mainly focusing on outdoor lighting for reducing electricity consumption as well as greenhouse gas emission. According to the study by INEGI, the average penetration of LED in residential rooms is just 12% in the country. Recently, the government has initiated the project to replace all the streetlights in the Guadalajara city, half of the total 80,000 streetlights in the city across 200 districts along 100 roads. The project is reportedly selffinanced with the energy savings it creates. The program is planned on a 10year leasing contract valued at MXN 300 million (close to USD 19 million). With this program, the city is expected to create savings of over USD 500,000 per month. The Servicio Express Aeropuerto Carret on MonterreyLaredo Highway needed an energyefficient lighting solution for the service station’s parking lot and canopy that covers the pumping stations. The authority has mentioned that by replacing the old 23 inefficient metal halide flood and canopy fixtures with LED enabled to save energy of 268,000 kWh and USD 32,160 in energy and maintenance. Industrial Use of LED Lighting in Mexico is Expected to Grow Significantly With around 621 medical device manufacturing companies, Mexico is one of the largest exporters of medical devices to the United States, and parts of Latin America, known for its high quality. With export revenues going as high as USD 9 billion, in 2019, medical device manufacturers are having zero tariffs on imports and exports under NAFTA. This makes Mexico a potential destination for setting up a UVbased medical device franchise, which is one of the highest growing fields of UVLED light applications. Mexico has a severe freshwater shortage, and the reuse of water is extensively practiced across the region. Considering this, UVbased consumer products, like sterilizers and disinfectants, are expected to gain importance over the forecast period considering that 80% are urban population, according to the World Bank. Additionally, the WHO has stated that the use of UVbased disinfectants is becoming prevalent in the country; hence, healthcareassociated infections (HAIs) are the most common reasons for death. Vendors offering LED solutions are expanding their presence in Mexico to support ongoing local demand. For instance, Aquionics, a part of the Halma Group, and a prominent UVLED based disinfectant product manufacturer, has strengthened its team in Mexico, anticipating the demand for industrial LED lighting. Competitive Landscape The Mexican LED lighting market is highly fragmented, with the presence of a large number of domestic as well as international players in the country. Due to the fragmented nature of the market, the competition among the players is high. March 2020 Signify announced the completion of the acquisition of Cooper Lighting Solutions from Eaton for USD 1.5 billion. With this acquisition, the company has planned to focus on the innovation of connected lightings and systems. This is estimated to drive the revenue growth of the company in the North American market with an aimed increase in professional revenues from 42% to 53%. February 2020 Signify introduced a new integrated Philips Combo Charge Controller for streetlights, enabling the emergence of a hybrid solar system. With this innovation, the company is aiming at creating a new market for solar powered outdoor lightings in Asia, Africa, South America, Australia, and Spain, where the company has already installed solarpowered lights. Reasons to Purchase this report: The market estimate (ME) sheet in Excel format 3 months of analyst support Please note: This publisher does offer titles that are created upon receipt of order. If you are purchasing a PDF Email Delivery option above, the report will take approximately 2 business days to prepare and deliver.\nLearn how to effectively navigate the market research process to help guide your organization on the journey to success.Download eBook", "pred_label": "__label__POS", "pred_score_pos": 0.9691714644432068}
{"content": "Patients stopped taking warfarin 5 days before their procedure, and began subcutaneous dalteparin, 100 IU/kg, or an identical placebo 3 days before the procedure. The dalteparin/placebo was stopped 24 hours before the procedure and restarted after the procedure, until the patient’s INR was in the therapeutic range. Warfarin was resumed on the evening of the procedure or the following day.\nThe primary efficacy outcome was ATE, including stroke, TIA, or systemic embolism. The primary safety endpoint was major bleeding (defined as bleeding at a critical anatomic site, symptomatic or clinically overt bleeding, or a decrease in hemoglobin >2 g/dL). Secondary efficacy and safety outcomes included minor bleeding, acute myocardial infarction, deep vein thrombosis, pulmonary embolism, and death. Outcomes were assessed within 37 days of the procedure.\nThe incidence of ATE was 0.4% (4 events) in the no-bridging group vs 0.3% (3 events) in the bridging group (95% CI, -0.6 to 0.8;\nP=.01 for non-inferiority; P=.73 for superiority). Major bleeding occurred in 1.3% of the no-bridging group (12 events) and in 3.2% of the bridging group (29 events), indicating that no bridging was superior in terms of the major bleeding outcome (number needed to harm [NNH]=53; relative risk [RR]=0.41; 95% CI, 0.20-0.78; P=.005). The no-bridging group also had significantly fewer minor bleeds in comparison to the bridging group (NNH=11; 12% vs 20.9%; P<.001). There were no differences between groups in other secondary outcomes.\nWHAT'S NEW: High-quality evidence suggests it’s OK to stop warfarin before surgery\nThis is the largest good-quality study to evaluate perioperative bridging in patients with atrial fibrillation who were at low or moderate risk for ATE (CHADS\n2 score 0-4). Previous studies suggested bridging increased bleeding and offered limited benefit for reducing the risk of ATE. However, this is the first study to include a large group of moderate-risk patients (CHADS 2 score 3-4). This trial provides high-quality evidence to support the practice of simply stopping warfarin in the perioperative period, rather than bridging with LMWH.\nCAVEATS: Findings might not apply to patients at highest risk\nMost patients in this study had a CHADS\n2 score ≤3. About 3% had a CHADS 2 score ≥5 or higher. It’s not clear whether these findings apply to patients with a CHADS 2 score of 5 or 6.\nThis trial categorized ATE risk using the CHADS\n2 score, rather than the CHA 2DS 2-VASc, which includes additional risk factors and may more accurately predict stroke risk. Both patients who received bridging therapy and those who did not had a lower rate of stroke than predicted by CHADs 2. This may reflect a limit of the predictive value of CHADS 2, but should not have affected the rate of bleeding or ATE outcomes in this study.\nCHALLENGES TO IMPLEMENTATION: Physicians may hesitate to disregard current guidelines\nStrokes are devastating events for patients, families, and physicians, and they pose a greater risk of morbidity and mortality compared to bleeding. However, this study suggests patients who receive bridging have a higher risk of bleeding than stroke, which is in contrast to some physicians’ experience and current recommendations.\nA physician caring for a patient who’s had a stroke may be inclined to recommend bridging despite the lack of efficacy and evidence of bleeding risk. Additionally, until guidelines reflect the most current research, physicians may be reluctant to provide care in contrast to these recommendations.\nACKNOWLEDGEMENT The PURLs Surveillance System was supported in part by Grant Number UL1RR024999 from the National Center For Research Resources, a Clinical Translational Science Award to the University of Chicago. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Center For Research Resources or the National Institutes of Health.", "pred_label": "__label__POS", "pred_score_pos": 0.7386493682861328}
{"content": "If you have performed a gastric bypass you may wonder if behind this operation you can re-gain weight. Well, if so do not overlook this note to determine whether fat\ndiet and are part of the same process, after bariatric surgery. Gastric bypass\nThe bariatric surgery is a treatment that can be useful for treating obesity in certain circumstances. Despite these benefits, there are many concerns and questions that may arise, such as whether you can return to not gain\nweight. Can you re-gain weight after a gastric bypass?\nThe answer is yes. According to scientific data, between 20-87% of patients who have undergone the largest bariatric surgery to 2 years, they have gained weight. The magnitude of weight gain ranges from half a kilo to 60 kilos. Weight gain is frequently occurs between 3-6 years after surgery.\nFor some doctors, the 25% increase of the\nweight lost is enough to have another surgery. There are even cases that have not only gained weight but have regained diabetes. What causes weight gain?\nDecreased metabolism. Apparently after weight reduction induced by bariatric surgery, there is a reduction in basal metabolism, which contributes to weight pregnancies long term.\nSedentary. Another cause that can cause\nweight gain is inactivity, thereby incorporating physical activity is essential to complement the postoperative .\nIncreased food intake. If you have not done the relevant nutritional reeducation you can suffer from weight gain. According to some researchers, those who initially ate 900 calories / day, after 2 and a half increased their intake to 1400 cal / day. Frequent consumption of carbohydrates is associated with this weight gain, independent of caloric intake. If you consume high glycolic foods you consume, these stimulate insulin production and decrease biolysis.\nGastric bypass\nWeight loss surgery can help you lose weight, but unless you change some habits and food can fatten again. Reeducation Food and incorporating exercise are key to maintaining\nweight loss you have achieved after the thinning process.", "pred_label": "__label__POS", "pred_score_pos": 0.8193936944007874}
{"content": "On various road-based vehicles, including cars, buses, and trucks, automotive mechanics inspect, service, and perform repairs. Sites of employment vary. In a private or small auto-body or repair shop, an auto mechanic may function. They may also work at a gas station or for a car dealership. State or federal employees responsible for maintaining state vehicles, police cars, fire trucks, or vehicles for road maintenance are some auto mechanics.Learn more about us at\nmechanic near me\nMost auto mechanics on a standard vehicle are capable of servicing all basic needs. Mechanics can sometimes specialise in a certain part of the vehicle, such as the transmission, breaks, or engine. They may also be specialised by vehicle type or make, such as a mechanic specialising in all types of buses or some brand names, such as Subaru or Toyota. In a shop matching their specialisation, a specialised mechanic is more likely to work. For instance, a Toyota mechanic would probably work at a Toyota dealership or support centre. As members of teams, specialised mechanics can also work with each mechanic taking on a different part of the vehicle. As they are assembled and prepared for shipping to dealers, car manufacturers will also hire mechanics to inspect vehicles for quality. As cars come off the assembly line, the mechanic may need to make adjustments or minor repairs. Any mechanic has the first task of analysing the problem and determining its source. The mechanic’s ability to find problems difficult to locate is both a source of professional pride and recommendation. Once the problem has been found by a mechanic, they will then locate and instal whatever replacement parts are needed to correct it. Depending on the component, the mechanic will often need to locate and order parts from shops or specialised dealers.\nThey may also be client service agents, depending on the workplace of the mechanic. Mechanics working for small repair shops or dealerships will often discuss the issue and the possible solution with car owners. This may require a mechanic to sell their abilities or services to the client who is likely to shop around for their repairs for the best deal. A mechanic may also choose to start or take over a mechanical business of his own.", "pred_label": "__label__POS", "pred_score_pos": 0.6959588527679443}
{"content": "Police today carry multiple devices to safely respond to the communities they serve. This TechCapsule explores the realities of using wireless power technology, such as near-field and far-field wireless charging, to charge officer’s devices. The document provides key takeaways for police chiefs to understand about current use in policing, and what the future may look like for these products.\nSkip back to main navigation", "pred_label": "__label__POS", "pred_score_pos": 0.8650343418121338}
{"content": "Despite the hysterics of far-right nationalists, influxes of refugees have the potential to positively impact economies all over the world. Take Germany, which faces a shortage of over one million skilled workers, with 60% of companies citing finding skilled workers as their biggest challenge.\nYet many refugees find themselves at a disadvantage when compared to native workers because they did not have the opportunity to develop crucial job skills in their birth countries. As Achim Dercks, deputy managing director of the Association of German Chambers of Industry puts it, “Someone who comes from Eritrea and says he was an electrician might have repaired a radio or laid a cable there, but he might have never seen a fuse box, as we use it.”\nNGOs and nonprofits can play a vital role in helping refugees enter the workforce by providing training on essential job skills and assistance with job placement. Based on Sonata Learning’s experience developing training programs for NGOs/nonprofits, major manufacturing/industrial clients and the trades, we offer the following recommendations:", "pred_label": "__label__POS", "pred_score_pos": 0.9290544986724854}
{"content": "In his workshop, Dr. Banting will explore the historical underpinnings of multiculturalism policy in the Canadian federation, broadly comparing it to other complex and diverse democratic societies. He will take participants through the many challenges and road blocks that this country has faced over the last 150 years in terms of managing diversity through public policy: what has gone wrong? and what has gone right?\nHe will also explore with participants the many ways in which an ever diversifying society might cope with the upcoming challenges our democracy will face in the future, the politics of backlash and the uniqueness of the Canadian context. He will explore the types of policy responses that governments in Canada can implement to ease into the next 150 years.", "pred_label": "__label__POS", "pred_score_pos": 0.6964274644851685}
{"content": "WILMINGTON, North Carolina—January 30, 2020—GE Hitachi Nuclear Energy (GEH) today announced that it has officially begun the regulatory licensing process for its BWRX-300 small modular reactor.\nOn December 30, 2019 the company submitted the first licensing topical report (LTR) for the BWRX-300 to the U.S. Nuclear Regulatory Commission (NRC). GEH expects such LTRs to serve as a foundation for the development of a Preliminary Safety Analysis Report that could potentially be submitted to the NRC by a utility customer.\n\"Embarking on the U.S. licensing process is a significant milestone in the commercialization of the BWRX-300,\" said Jon Ball, Executive Vice President of Nuclear Products for GEH. \"The first licensing topical report was submitted to the NRC at the end of 2019 as part of an aggressive timeline that we set for ourselves. As the global demand for carbon-free energy increases, we are seeing significant interest in this groundbreaking SMR technology and are excited about continuing to work toward U.S. licensing.\"\nThe BWRX-300 is a 300 MWe water-cooled, natural circulation SMR with passive safety systems that leverages the design and licensing basis of GEH’s U.S. NRC-certified ESBWR. Through dramatic design simplification, GEH projects the BWRX-300 will require significantly less capital cost per MW when compared to other water-cooled SMR designs or existing large nuclear reactor designs.\nBy leveraging the existing ESBWR design certification, utilizing licensed and proven nuclear fuel designs, incorporating proven components and supply chains and implementing simplification innovations the BWRX-300 can, GEH believes, become cost-competitive with power generation from combined cycle gas plants and renewable energy platforms.\nAs the tenth evolution of GE’s first Boiling Water Reactor (BWR) design, GEH’s BWRX-300 represents the simplest, yet most innovative BWR design since GE began commercializing nuclear reactors in 1955.\nAbout GE Hitachi Nuclear Energy\nBased in Wilmington, N.C., GE Hitachi Nuclear Energy (GEH) is a world-leading provider of advanced reactors and nuclear services. Established in 2007, GEH is a global nuclear alliance created by GE and Hitachi to serve the global nuclear industry. The nuclear alliance executes a single, strategic vision to create a broader portfolio of solutions, expanding its capabilities for new reactor and service opportunities. The alliance offers customers around the world the technological leadership required to effectively enhance reactor performance, power output and safety. Follow GEH on LinkedIn and Twitter.\n###\nFor media inquiries, please contact:Jon Allen\nGE Hitachi Nuclear Energy\n+1-910-819-2581\n[email protected]", "pred_label": "__label__POS", "pred_score_pos": 0.7959465980529785}
{"content": "According to the latest report by IMARC Group, titled\n\"China Ceramic Ball Bearing Market: Industry Trends, Share, Size, Growth, Opportunity and Forecast 2020-2025,\" the ceramic ball bearing market size in China reached US$ 231 Million in 2019. Ceramic ball bearings are widely used to reduce the friction between moving rotary parts of an instrument or equipment. They comprise numerous parts, such as the cage, steel balls and outer and inner rings. They are essential in efficiently transmitting power and offering smooth and low friction motion by supporting both axial and radial loads. Ceramic variants are superior in quality and offer improved durability when compared to the stainless-steel bearings. They are capable of withstanding extreme physical impact and can efficiently work when placed under harsh temperatures and high corrosion environments. They require lesser amounts of energy due to their high speed. Since they are characterized by smoother and rounder surfaces, their usage also assists in reducing friction while offering higher dimensional stability.\nWe are regularly tracking the direct effect of COVID-19 on the market, along with the indirect influence of associated industries. These observations will be integrated into the report.\nChina Ceramic Ball Bearing Market Trends:\nThe market is primarily driven by a significant increase in vehicle production in China. This can be attributed to the increasing expenditure capacities and the competitive pricing of the majority of the automobiles, which, in turn, is escalating the sales of automobiles across urban and rural areas. In addition to this, several favorable government policies, such as reduced purchase fees for new cars and subsidies for car-buyers in rural areas, are acting as another growth-inducing factor. The increasing exports of vehicles have also contributed to the industry growth, as China has a well-established foothold on numerous foreign markets. Since ceramic ball bearings operate at relatively faster speeds and perform exceptionally well when subjected to harsh conditions, they form an essential component in the production of numerous automobiles. Apart from this, the country has a strong aftermarket for industrial equipment and motor vehicle repair, which uses these bearings as a preferred option. Hybrid ceramic ball bearings are gaining preference for repair purposes as their utilization minimizes the overall cost of the repair and results in reduced operating costs. Furthermore, numerous key players are equipping these ball bearings with advanced technologies and lightweight materials to improve the overall performance, thereby creating a positive outlook for the market. On account of the aforementioned factors, the market is expected to exhibit moderate growth during 2020-2025.\nMarket Summary:\nOn the basis of the raw material, the market has been divided into zirconium oxide, silicon nitride and others.\nBased on the product type, the market has been bifurcated into hybrid and full ceramic ball bearings.\nOn the basis of the application, the market has been classified into electric motors, automobiles, underwater equipment, laboratory equipment, aerospace and others.\nOn the geographical front, the market has been segmented into Guangdong, Jiangsu, Shandong, Zhejiang, Henan and Others.\nThe competitive landscape of the market has been studied in the report with the detailed profiles of the key players operating in the market.\nAbout Us:\nIMARC Group is a leading market research company that offers management strategy and market research worldwide. We partner with clients in all sectors and regions to identify their highest-value opportunities, address their most critical challenges, and transform their businesses.\nIMARC’s information products include major market, scientific, economic and technological developments for business leaders in pharmaceutical, industrial, and high technology organizations. Market forecasts and industry analysis for biotechnology, advanced materials, pharmaceuticals, food and beverage, travel and tourism, nanotechnology and novel processing methods are at the top of the company’s expertise.\nContact US\nIMARC Group\n30 N Gould St, Ste R\nSheridan, WY (Wyoming) 82801 USA\nEmail: Sales@imarcgroup.com\nTel No:(D) +91 120 433 0800\nAmericas:- +1 631 791 1145 | Africa and Europe :- +44-702-409-7331 | Asia: +91-120-433-0800, +91-120-433-0800", "pred_label": "__label__POS", "pred_score_pos": 0.6218136548995972}
{"content": "ISCAN (Integrated Service for Children with Additional Needs) in Tameside and Glossop supports 655 children in the community with disabilities and complex health needs. Many require regular suction treatment to keep their lungs clear of mucus and allow them to breathe more easily.\nWe have funded suction machines for ISCAN in the past to help them to cope with the high demand for them. However, the pandemic will see a sharp rise in the numbers seeking treatment for breathing difficulties and will put even more pressure on already overstretched resources, as it will for hospitals and health services throughout the UK.", "pred_label": "__label__POS", "pred_score_pos": 0.5252150297164917}
{"content": "Escherichia coli O157:H7 is a foodborne pathogen, implicated in various multi-state outbreaks. It encodes Shiga toxin on a prophage, and Shiga toxin production is linked to phage induction. An E. coli strain, designated 0.1229, was identified that amplified Stx2a production when co-cultured with E. coli O157:H7 strain PA2. Growth of PA2 in 0.1229 cell-free supernatants had a similar effect, even when supernatants were heated to 100°C for 10 min, but not after treatment with Proteinase K. The secreted molecule was shown to use TolC for export and the TonB system for import. The genes sufficient for production of this molecule…\nTwo Marinobacter sp. NP-4 and NP-6 were isolated from a deep oceanic basaltic crust at North Pond, located at the western flank of the Mid-Atlantic Ridge. These two strains are capable of using multiple carbon sources such as acetate, succinate, glucose and sucrose while take oxygen as a primary electron acceptor. The strain NP-4 is also able to grow anaerobically under 20?MPa, with nitrate as the electron acceptor, thus represents a piezotolerant. To explore the metabolic potentials of Marinobacter sp. NP-4 and NP-6, the complete genome of NP-4 and close-to-complete genome of NP-6 were sequenced. The genome of NP-4 contains…\nShewanella baltica 128 is a specific spoilage organism (SSO) isolated from the refrigerated shrimp that results in shrimp spoilage. This study reported the complete genome sequencing of this strain, with the primary annotations associated with amino acid transport and metabolism (8.66%), indicating that S. baltica 128 has good potential for degrading proteins. In vitro experiments revealed Shewanella baltica 128 could adapt to the stress conditions by regulating its growth and biofilm formation. Genes that related to the spoilage-related metabolic pathways, including trimethylamine metabolism (torT), sulfur metabolism (cysM), putrescine metabolism (speC), biofilm formation (rpoS) and serine protease production (degS), were identified.…\nChemical defense against predators is widespread in natural ecosystems. Occasionally, taxonomically distant organisms share the same defense chemical. Here, we describe an unusual tripartite marine symbiosis, in which an intracellular bacterial symbiont (“Candidatus Endobryopsis kahalalidefaciens”) uses a diverse array of biosynthetic enzymes to convert simple substrates into a library of complex molecules (the kahalalides) for chemical defense of the host, the alga Bryopsis sp., against predation. The kahalalides are subsequently hijacked by a third partner, the herbivorous mollusk Elysia rufescens, and employed similarly for defense. “Ca E. kahalalidefaciens” has lost many essential traits for free living and acts as a…\nMicrobacterium sp. strain SGAir0570 was isolated from air samples collected in Singapore. Its genome was assembled using single-molecule real-time sequencing and MiSeq short reads. It has one chromosome with a length of 3.38?Mb and one 59.2-kb plasmid. It contains 3,170 protein-coding genes, 48 tRNAs, and 6 rRNAs.Copyright © 2019 Kalsi et al.\nShiga toxin-producing Escherichia coli O157:H7 is a foodborne pathogen and is responsible for outbreaks of human gastroenteritis. This report documents the draft genome sequences of nine O157:H7 cattle strains, which were identified to be PCR positive for a Shiga toxin gene but displayed different levels of functional toxin activity.\nThe bacteriophage exclusion (BREX) system is a novel prokaryotic defense system against bacteriophages. To our knowledge, no study has systematically characterized the function of the BREX system in lactic acid bacteria. Lactobacillus casei Zhang is a probiotic bacterium originating from koumiss. By using single-molecule real-time sequencing, we previously identified N6-methyladenine (m6A) signatures in the genome of L. casei Zhang and a putative methyltransferase (MTase), namely, pglX This work further analyzed the genomic locus near the pglX gene and identified it as a component of the BREX system. To decipher the biological role of pglX, an L. casei Zhang pglX mutant…\nHere, we report the full-genome sequence of an NAD-hemin-independent Avibacterium paragallinarum serovar C-2 strain, FARPER-174, isolated from layer hens in Peru. This genome contained 12 potential genomic islands that include ribosomal protein-coding genes, a nadR gene, hemocin-coding genes, sequences of fagos, an rtx operon, and drug resistance genes. Copyright © 2019 Tataje-Lavanda et al.\nEnteropathogenic Escherichia coli (EPEC) is a leading cause of moderate to severe diarrhea among young children in developing countries, and EPEC isolates can be subdivided into two groups. Typical EPEC (tEPEC) bacteria are characterized by the presence of both the locus of enterocyte effacement (LEE) and the plasmid-encoded bundle-forming pilus (BFP), which are involved in adherence and translocation of type III effectors into the host cells. Atypical EPEC (aEPEC) bacteria also contain the LEE but lack the BFP. In the current report, we describe the complete genome of outbreak-associated aEPEC isolate E110019, which carries four plasmids. Comparative genomic analysis demonstrated…\nThe severity of environmental conditions at Earth’s frigid zones present attractive opportunities for microbial biomining due to their heightened potential as reservoirs for novel secondary metabolites. Arid soil microbiomes within the Antarctic and Arctic circles are remarkably rich in Actinobacteria and Proteobacteria, bacterial phyla known to be prolific producers of natural products. Yet the diversity of secondary metabolite genes within these cold, extreme environments remain largely unknown. Here, we employed amplicon sequencing using PacBio RS II, a third generation long-read platform, to survey over 200 soils spanning twelve east Antarctic and high Arctic sites for natural product-encoding genes, specifically targeting…\nUsing bacteria to transform reactive corrosion products into stable compounds represents an alternative to traditional methods employed in iron conservation. Two environmental Aeromonas strains (CA23 and CU5) were used to transform ferric iron corrosion products (goethite and lepidocrocite) into stable ferrous iron-bearing minerals (vivianite and siderite). A genomic and transcriptomic approach was used to analyze the metabolic traits of these strains and to evaluate their pathogenic potential. Although genes involved in solid-phase iron reduction were identified, key genes present in other environmental iron-reducing species are missing from the genome of CU5. Several pathogenicity factors were identified in the genomes of…\nVariable region analysis of 16S rRNA gene sequences is the most common tool in bacterial taxonomic studies. Although used for distinguishing bacterial species, its use remains limited due to the presence of variable copy numbers with sequence variation in the genomes. In this study, 16S rRNA gene sequences, obtained from completely assembled whole genome and Sanger electrophoresis sequencing of cloned PCR products from Serratia fonticola GS2, were compared. Sanger sequencing produced a combination of sequences from multiple copies of 16S rRNA genes. To determine whether the variant copies of 16S rRNA genes affected Sanger sequencing, two ratios (5:5 and 8:2)…\nNon-O157 Shiga toxin-producing Escherichia coli (STEC) strains are a common source of foodborne illness. STEC O111 is among the most prevalent non-O157 STEC serogroups. Few completed genomes of STEC O111 strains have been reported to date. We report here the complete genomic sequences of three O111:H8 strains that display a distinct aggregation phenotype.\nWe characterized 170 complete genome assemblies from clinical Bordetella pertussis isolates representing geographic and temporal diversity in the United States. These data capture genotypic shifts, including increased pertactin deficiency, occurring amid the current pertussis disease resurgence and provide a foundation for needed research to direct future public health control strategies.\nEnterovirulent Escherichia coli infections cause significant losses in the pig industry. However, information about the structures of the virulence and multidrug resistance (MDR) plasmids harboured by these strains is sparse. In this study, we used whole-genome sequencing with PacBio and Illumina platforms to analyse the molecular features of the multidrug-resistant enterotoxigenic E. coli (ETEC) strain 14OD0056 and the multidrug-resistant hybrid Shiga toxin-producing/enterotoxigenic E. coli (STEC/ETEC) strain 15OD0495 isolated from diarrheic pigs in Switzerland. Strain 14OD0056 possessed three virulence plasmids similar to others previously found in ETEC strains, while 15OD0495 harboured a 119-kb multivirulence IncFII/IncX1 hybrid STEC/ETEC plasmid (p15ODTXV) that co-carried…", "pred_label": "__label__POS", "pred_score_pos": 0.5524536371231079}
{"content": "PHANTOM PAIN What is Phantom Pain?\nIf you have lost a limb or another part of your body, you may feel painful sensations that seem to be coming from the missing part. This phenomenon is called “phantom pain.” It is common among amputees. It could become a chronic problem for some people.\nPhantom pain is believed to be linked to your brain and nervous system. When a piece of your body is removed, your brain no longer receives sensory signals from that area. Your confused brain may remap itself. It may begin to associate the missing part with another part of your body. This leads to painful sensations. Damaged nerves near the site of your amputation may also play a role in your pain.\nSymptoms of phantom pain after begin shortly after your amputation. You may feel stabbing, burning sensations. You may feel as if the missing part is being squeezed. It may throb. You may feel like the missing part is being bent it to a painful position. These sensations may come and go, or you may feel them all the time.\nTreatment options may include medications, nerve stimulation and other therapeutic techniques. Your healthcare providers at Pain MD Houston can create a care plan that is right for your needs.", "pred_label": "__label__POS", "pred_score_pos": 0.6991252899169922}
{"content": "At Living Holistic Health, we offer natural alternatives to improve your health and wellness. Our experienced and professional practitioners address the underlying drivers of your symptoms and use naturopathic and nutritional medicine to treat the causes.\nDelving into both conventional and traditional medicine, we explore the best of both worlds and address issues the natural way. Always up to date with the latest scientific research, testing, natural medicines, and partaking in ongoing training and seminars, we bring our knowledge and tools to the table to enhance your lifestyle.\nWhat sets us apart from other healthcare clinics is that we take the time to look at the person as a whole, including their history, diet and lifestyle. Our approach is thorough and shaped around a holistic framework that allows us to make educated decisions that will benefit the patient. We don't just focus on the symptom and prescribe a drug for it; we aim to understand the causes and provide a natural solution that'll benefit you for years to come.\nOUR SERVICES – HOW WE CAN HELP YOU\nFully qualified, registered and professional, our team of practitioners specialise in just some of the following services:\n- Digestive issues including Food Allergies, Intolerances and IBS.\n- Weight loss and dietary planning\n- Mood and Stress Disorders including Anxiety, Depression and Insomnia.\n- Autoimmune Diseases including Thyroid, Multiple Sclerosis, Alzheimer's Disease, Ulcerative Colitis, Coeliac Disease, and Rheumatoid Arthritis.\n- Women's Health including Fertility Issues, PMS, Menopause and PCOS.\n- Children's Health including Autistic Spectrum Disorders, ADHD and Allergies.\n- Metabolic conditions including Diabetes management, Type 1 & 2 and Insulin resistance.\n- Weight loss, weight management and high blood pressure.\n- Fatigue states and insomnia.\n- Sports nutrition.\n- Healthy ageing.", "pred_label": "__label__POS", "pred_score_pos": 0.9461365342140198}
{"content": "The Special of the Day… From the Orange Moon Cafe…\n\"All Is Well. All Is Not Well\"\nUltimately, all is well. God's eternal purpose in Christ will be fulfilled. His trusting children in Christ will be glorified. And His determination to exalt Christ proceeds to the inevitable culmination of His Son's exaltation and rule.\n\"Then cometh the end, when He shall have delivered up the kingdom to God, even the Father, when He shall have put down all rule and authority and power. For He must reign until He hath put all enemies under His feet\" (I Corinthians 15:24-25).\nIn temporal, earthly terms, however, all is not well. God is not satisfied with things as they are, nor should we be. The Lord Jesus taught His disciples to pray, \"Thy kingdom come, Thy will be done,\" clearly confirming our need to long for a coming day of righteousness that has not yet arrived (Matthew 6:10). The peace we have in Christ does not preclude a restless discontent with a \"world which lieth in wickedness\" (I John 5:19). Bible believing Christians are not \"que sera, sera\" fatalists who blithely and without compassion assign all things to God's determinate will. Scripture loses all meaning if we fail to see a Lord whose ultimate purposes will be fulfilled, but who grieves about the world as presently constituted.\nAgain, however, in the ultimate sense, all is well. Thus, we live in the spiritual dichotomy of assurance and disturbance. We rejoice in the Lord Jesus and His abundant provision for a heart maintained in peace and joy amid the turmoil of a fallen world. We also sorrow as we see the effects of sin and its horrific degradation. Reality demands that we journey upon these dual rails of awareness so plainly laid down by the revelation of Scripture. \"As sorrowful, yet always rejoicing\" testified the Apostle Paul who so well knew both tracks of \"all is well\" and \"all is not well\" (II Corinthians 6:10). We must join our brother of old in the challenging perception and response that requires both gratitude and grieving. \"Serve the Lord with gladness… Blessed are they that mourn\" (Psalm 100:2; Matthew 5:4). We look into the heart of Christ and find our own hearts filled with light. We also, however, look at the realities of this present fallen planet and find our hearts hurting and often even broken. It must presently be this way, and it will if we walk in the light of God's Truth. \"Rejoice with them that do rejoice, and weep with them that weep\" (Romans 12:15).\nThe mystery of God's way transcends our full understanding. An all powerful Being made angels and people with the freedom to reject Him and bring utter catastrophe upon His creation. He did so knowing that this would require His beloved Son to suffer and die by His own \"determinate counsel and foreknowledge\" (Acts 2:23). Moreover, God knew He would have to pour out His fury against sin upon the Lord Jesus so that He might save us from the \"wrath to come\" (I Thessalonians 1:10). He nevertheless created all things according to the perfection of His love and wisdom. He made a universe that would bring Him both joy and grief, a creation that would ultimately become all He intended it to be, but not before grave darkness and sorrow descended upon it. Yes, all is well when we look at the full picture. But all is not yet well when the scenes of a fallen and dying world disturb our hearts. These are the rails, the rails of Truth upon which we presently journey. All is well. All is not well. We must accept the blessed but difficult perspective, joining Paul in being \"sorrowful, yet always rejoicing.\"\n\"Even in laughter the heart is sorrowful, and the end of that mirth is heaviness.\"\n(Proverbs 14:13)\nWeekly Memory Verse\n\"Blessed be the God and Father of our Lord Jesus Christ, who hath blessed us with all spiritual blessings in heavenly places in Christ.\"\n(Ephesians 1:3)\n5551", "pred_label": "__label__POS", "pred_score_pos": 0.5842431783676147}
{"content": "Session Information Date: Monday, November 9, 2020 Session Type: Poster Session D Session Time: 9:00AM-11:00AM Background/Purpose: Among children diagnosed with systemic lupus erythematosus (SLE), there exists monogenic forms of SLE, where rare variants in a single gene lead to disease. The aim of this study was to calculate the burden of rare variants in monogenic SLE genes, in children suspected of monogenic SLE or lupus-like disease. Methods: From the Hospital for Sick Children (SickKids) Lupus clinic, we identified patients suspected of monogenic SLE due to young-onset disease (< 11y), one or more affected first-degree relatives, and/or history of consanguinity. We completed paired end whole genome sequencing (WGS) using an Illumina HiSeq X platform (n=69) or paired end whole exome sequencing (WES) with an Illumina HiSeq 2500 platform (n=3). Variant calling was performed with GATK and HAS, and functional annotation with ANNOVAR. We prioritized rare exonic variants (MAF< 1%) based on predicted functional impact (frameshift, nonsynonymous and stop-gain) and 36 monogenic lupus genes. Chi-squared tests identified a subset of variants with an increased burden in monogenic SLE cases compared to relevant ethnic controls (Bonferroni correction p< 8.9E-4). Polyphen, SIFT and CADD scores (≥30) predicted damaging and/or deleterious variants.\nParticipants also underwent genotyping on the Illumina multiethnic MEGA or GSA array. Ancestry was genetically inferred using principal component and ADMIXTURE, or by self-report (Canada census ethnicity categories). Additive non-HLA and HLA SLE genetic risk scores (GRSs) were calculated using common risk single nucleotide polymorphisms. We tested the relationship between GRSs and the number of rare monogenic SLE variants with functional impact using Spearman correlation (r\ns) coefficients. Results: The cohort included 72 suspected monogenic SLE patients, 65 with SLE and 7 with lupus-like disease (79% females), with a median age of diagnosis of 8 years (IQR=7,10). The majority of patients were admixed (33%) or European (29%). WGS analysis showed 1032 rare variants in monogenic SLE genes, with a median of 17 variants/gene (IQR= 10,32) and 14 variants/person (IQR=11,17). We identified 56 exonic variants with predicted functional impact, of which 18 variants in 24 patients had a significantly higher frequency in monogenic SLE cases compared to referent populations. We found 7 variants predicted to be disease-causing in 9 SLE patients, in genes: C1QA, C1QC, C1R, C4B, DNASE1L3 and MAN2B1 (Table).\nIn 68 individuals with calculated GRSs, we did not observe a correlation between the burden of rare monogenic SLE variants with functional impact and SLE HLA GRS (r\ns= 0.11, p=0.65) or non-HLA GRS (r s= 0.04, p=0.78) (Figure). Conclusion: In our cohort of suspected monogenic SLE patients, WES/WGS identified a likely causal genetic variant in 13% of patients. We did not detect a significant correlation between the number of rare monogenic SLE variants with functional impact and non-HLA or HLA GRS. Studies with larger cohort sizes are needed to validate our findings.\nTable. Frequency of predicted deleterious monogenic SLE variants in monogenic SLE cases compared to referent populations. (1) MAF reported for relevant referent population in gnomAD v2.1.1. (2) Chi-squared tests used to compare cSLE and referent variant frequencies. (3) Variant found in more than one monogenic cSLE patient.\nDisclosure: M. Misztal, None; F. Liao, None; S. Naumenko, None; A. Knight, None; D. Dominguez, None; J. Cao, None; D. Webber, None; B. Thiruvahindrapuram, None; D. Levy, None; A. Paterson, None; E. Silverman, None; L. Hiraki, None.\nMisztal M, Liao F, Naumenko S, Knight A, Dominguez D, Cao J, Webber D, Thiruvahindrapuram B, Levy D, Paterson A, Silverman E, Hiraki L. Identifying Rare Genetic Variants in Childhood-onset Monogenic Systemic Lupus Erythematosus [abstract].\nTo cite this abstract in AMA style: Arthritis Rheumatol.2020; 72 (suppl 10). https://acrabstracts.org/abstract/identifying-rare-genetic-variants-in-childhood-onset-monogenic-systemic-lupus-erythematosus/. Accessed November 29, 2020.\n« Back to ACR Convergence 2020\nACR Meeting Abstracts - https://acrabstracts.org/abstract/identifying-rare-genetic-variants-in-childhood-onset-monogenic-systemic-lupus-erythematosus/", "pred_label": "__label__POS", "pred_score_pos": 0.5698646306991577}
{"content": "NCASE Resource Library Featured Resources\nThis publication features some of the best resources, including webinars, briefs, and toolkits, available in the online NCASE Resource Library, developed for both practitioners and system builders.\nThese selected resources, curated by NCASE, offer ideas and information for OST system leaders to support recovery from COVID-19.\nThe NCASE Out-of-School Time Professional Development System-Building Toolkit was designed to assist states as they build professional development systems inclusive of school-age providers.\nSearch for Resources ? Search Results Filter By Reset Selections Expand All Filters Topics Resource type Publisher Search Results Filter By\nThis issue brief outlines steps that public and private sector leaders can guide a comeback effort and build back better following COVID-19.\nThis annotated bibliography provides a list of fifteen links to evidence-based practices, policy briefs, survey resources, and webinars to support Dual Language Learners (DLL). It is designed for policymakers, school administrators, and teachers in early child and primary education settings, and is helpful for Out-of-School Time (OST).\nThis online module is designed to train program and fiscal leaders to work together. It comes with printable resources like a budget form and a game to encourage teamwork.\nThis PowerPoint presentation explores key principles for effective business management. It describes the concept of shared services. Some slides demonstrate the extensive resources of the ECE Shared Resources tool used by more than 20 states. It provides examples of strengthening business practices in New Hampshire and Pennsylvania.\nThis article defines parent engagement and why it benefits children, families, and afterschool programs. It provides 15 examples of promising practices. Sample outreach materials and parent surveys are included. This resource supports resilience.\nThis resource is for program leaders to explore cost allocation. It discusses why assigning a shared cost to 2 or more programs is important. It defines key costs and provides a step-by-step guide to cost allocation.\nThis resource includes a powerpoint, video and handouts that define leadership. It provides a foundational exploration of difference between leadership and management. It can be useful for emerging leaders and training and TA professionals for school-age.\nThis webinar explores ways to create a framework for continuity, consistency, equity and developmentally appropriate practice between early childhood and schools. The focus is on birth to grade three and can be helpful for school-age to consider. The ideas and state examples suggest we need to align practices and polices through cross-sector relationships.", "pred_label": "__label__POS", "pred_score_pos": 0.8311887383460999}
{"content": "Written by Michele Rae, centerwithin.com – 2016 Fall Retreat Keynote Speaker\nWhen you think about yourself, who do you know yourself to be?\nThere are specific characteristics you may identify with such as being a man or woman, American or Mexican, daughter or father. You may classify yourself by what you do such as a painter, entrepreneur, volunteer or inventor. I am a woman, teacher and writer, mother and mystic.\nThere are characteristics that are broader and reflect your tendencies and preferences such as being an introvert or extrovert or your political views. I value connection, new ideas, authenticity, being in nature, quiet, dark chocolate and red wine. (OK, maybe the wine and chocolate are more specific)\nWhere did these identifications come from? We are taught our story by external references from the time we are born. Our parents, educators, church, and society hold certain values to have higher meaning than others. They teach us to differentiate what is acceptable and to conform to their standards and customs. We often confuse our authentic story with the one we believe we “should” have or who we are “supposed” to be.\nWho would you be if you examined each of these identifications and released the ones that do not fit anymore or feel constricting? Which ones feel the most real, ring true and make your heart sing? Are there parts of you that have been hidden and are longing to come out and play?\nLucky for us, in addition to being a character in our story we are also an author! If you could write in events, feelings, experiences and characters to enhance your story, what would they be? I recommend one theme that runs through the entire story is “I AM worthy and lovable.” Require every small choice, every moment of every day, to reflect that theme. If you come across a person or circumstance in your life that denies that you are loveable and worthy, consider removing them from your story, or at least relegating them to a minor character!\nIn fact, at the heart of all stories, all that has a beginning, middle and end, is an essence of pure light and love. The inner essence, some traditions call it the Holy Spirt aspect of God, others the Divine Spark and others a Reflection of Source, is identical in every living being. Take a few minutes every day, or set a couple hours apart once in a while, to really feel into this Center Within aspect of yourself. When you know it, and write your story from your true nature, magic happens! and you", "pred_label": "__label__POS", "pred_score_pos": 0.5594198703765869}
{"content": "Ending youth homelessness involves a number of critical elements and actions. These include the implementation of innovative programs and housing solutions tailored for the specific needs of young people as well as structural changes within the operations of homeless-serving systems. The transformation of public systems, including child welfare, education, mental health, income supports and criminal justice and their enhanced integration which can facilitate broad systems of care is essential. Each community also has unique dynamics that must be accounted for in local efforts and plans.\nTo support the enhanced capacity to respond to youth homelessness in unique local contexts across Canada, A Way Home has developed a toolkit to help communities create plans to prevent, reduce and end homelessness among young people. This webinar will introduce the new toolkit to those who are considering or already leading community efforts to develop strategic responses to youth homelessness.\nThe toolkit is available here: homelesshub.ca/youthplantoolkit\nADDITIONAL LINKS:\n[Blog] Helping Communities Go Further Faster: Youth Homelessness Community Planning Toolkit by Melanie Redman\nhomelesshub.ca/blog/helping-communities-go-further-faster-youth-homelessness-community-planning-toolkit Living Library of resources - homelesshub.ca/toolkit/chapter/additional-resources Continue the conversation on the Community Workspace on Homelessness - homelesshub.ca/workspace", "pred_label": "__label__POS", "pred_score_pos": 0.8541734218597412}
{"content": "Variable Earnings and Nonlinear Taxation\nWe explore the interaction between two facts. The first is that income is variable; the second is that the tax and transfer system transforms before tax income into after tax income in highly non-linear ways. The effect is to penalize (and reward) income variability in a manner which is both substantial and capricious.", "pred_label": "__label__POS", "pred_score_pos": 0.6754028797149658}
{"content": "The Future Growth Loan Scheme currently makes up to €300 million of loans available with a term of 8-10 years and is operated by the Strategic Banking Corporation of Ireland (SBCI) though participating lenders. Funding made available by the scheme facilitates long-term, strategic investment.\nAs at 8 May 2020, the scheme has received 3,502 eligibility applications, with 3,327 approved, 160 currently in process and 16 deemed ineligible. The scheme has seen significant uptake and the initial €300m funding has been almost fully subscribed, supporting a significant level of strategic investment by businesses. On 2 May, I announced an expansion to the Future Growth Loan Scheme of €200m. Officials of my Department, the Department of Agriculture, Food and the Marine, the Department of Finance, and the SBCI are working to ensure this is available as soon as possible.\nThe scheme is underpinned by a 64% counter-guarantee from the European Investment Fund. This counter-guarantee provides significant risk protection to the Exchequer against potential losses from the loan guarantee scheme. The FGLS was established using the European Investment Fund Agreement Act 2018. This Act allows for the Minister for Business, Enterprise and Innovation and the Minister for Agriculture, Food and the Marine to enter into agreements with the European Investment Fund (EIF) to facilitate access to finance for qualifying enterprises.\nThere is a limit of €75 million set out in the Act on the total value of agreements (for First Loss payments) that the relevant Ministers can enter into with the EIF. Capacity currently remains within the aggregate limit set out in the Act to allow for an agreement with the EIF in relation to the planned €200m expansion of the FGLS.\nHowever, the European Investment Bank (EIB) Group recently announced, as part of the European Union response to COVID-19, that it would be providing €25 billion in guarantees to underpin €200 billion in funding for member States to mitigate the impact of COVID-19. For Ireland to be able to enter into additional agreements with the EIF, so as to leverage these EIB guarantees, will require an amendment to the aggregate limit set out in the European Investment Fund Agreement Act 2018.\nOfficials of my Department have been working urgently alongside the Office of Parliamentary Counsel on the drafting of legislation to amend the aggregate limit for agreements within the European Investment Fund Agreement Act 2018. The intention is that it will be progressed through the Oireachtas as a matter of urgency once a new Government is formed.", "pred_label": "__label__POS", "pred_score_pos": 0.9196920990943909}
{"content": "A representative curve number (CN) of a catchment is often calculated from the area-weighted average of CN values of unique land use and soil combinations. While convenient for implementation, this method is known to underestimate direct runoff depth. This paper investigates the mathematical mechanism of the expected underestimation and proposes alternative CN averaging methods, the quadratic and exact averaging methods, to handle the underestimation problem. Results suggest that the quadratic method could reduce the level of underestimation in direct runoff depth, and further the exact method could provide the same direct runoff depth as that of the area-weighted direct runoff depth averaging method. A representative CN is found to be a function of rainfall size as well as catchment landscape, and the underestimation is relatively large for small and mid-sized storm events. The improvement in runoff estimation with the newly proposed averaging methods is particularly beneficial to stormwater management, flood controls, and erosion controls upon small return-period events.", "pred_label": "__label__POS", "pred_score_pos": 0.990469217300415}
{"content": "This report furthers the STEM ecosystem research described in a Noyce Foundation 2014 working paper amd shares evidence of the impact of cross-sector partnerships in the effort to create a rich STEM learning environment for all students. This report outlines recommendations for further research and highlights lessons from the field, along with a toolkit that includes an adaptable logic model and recommended strategies.Read more", "pred_label": "__label__POS", "pred_score_pos": 0.9374251365661621}
{"content": "The Centers for Medicare & Medicaid Services (CMS) Center for Medicare and Medicaid Innovation(CMMI) is introducing the Part D Enhanced Medication Therapy Management (Enhanced MTM) Model, which will aim to free up stand-alone Part D Prescription Drug Plans (PDPs) in specified regions of the United States. This model will commence January 1, 2017 with a five-year performance period, and it will serve as a unique enhanced medication therapy management (MTM) program, waive current requirements for enrollment and offer a reward for meeting certain cost-reduction parameters.\nAccording to CMS, Enhanced MTM is intended to assess whether providing selected Medicare Prescription Drug Plans (PDPs) with additional incentives and flexibilities to design and implement innovative programs will better achieve the overall goals for MTM programs. These goals include:\nImproving compliance with medication protocols, including high-cost drugs, to ensure that beneficiaries receive the medications they need, and use them properly Reducing medication-related problems, such as duplicative or harmful prescription drugs, or suboptimal treatments Increasing patients’ knowledge of their medications to better achieve their or their prescribers’ goals of therapy Improving communication among prescribers, pharmacists, caregivers and patients\nComments, questions and responses regarding this model can be sent to [email protected]. The inquiry should identify the sender and the organization represented and be submitted by October 16, 2015 to receive full consideration.\nCMS will be holding a webinar October 21, 2015 at 2pm (EDT) to provide further details. For more information about the webinar, visit http://innovation.cms.gov/initiatives/enhancedmtm/index.html.", "pred_label": "__label__POS", "pred_score_pos": 0.9799939393997192}
{"content": "[eng] MET alterations may provide a potential biomarker to evaluate patients who will benefit from treatment with MET inhibitors. Therefore, the purpose of the present study is to investigate the utility of a liquid biopsy-based strategy to assess MET alterations in cancer patients. We analyzed MET amplification in circulating free DNA (cfDNA) from 174 patients with cancer and 49 healthy controls and demonstrated the accuracy of the analysis to detect its alteration in patients. Importantly, a significant correlation between cfDNA concentration and MET copy number (CN) in cancer patients (r = 0.57, p <10−10) was determined. Furthermore, we evaluated two approaches to detect the presence of MET on circulating tumor cells (CTCs), using the CellSearch® and Parsortix systems and monitored patients under anti-EGFR treatment (n = 30) combining both cfDNA and CTCs analyses. This follow-up provides evidence for the potential of MET CN assessment when patients develop resistance to anti-EGFR therapy and a significant association between the presence of CTCs MET+ and the Overall Survival (OS) in head and neck cancer patients (P = 0.05; HR = 6.66). In conclusion, we develop specific and noninvasive assays to monitor MET status in cfDNA/CTCs and demonstrate the utility of plasma MET CN determination as a biomarker for monitoring the appearance of resistance to anti-EGFR therapy.", "pred_label": "__label__POS", "pred_score_pos": 0.9630938172340393}
{"content": "dc.description.abstract This study investigated the relationship between participation in competitive sports and\nacademic performance of secondary school students in Kenya. It was hypothesized\nthat athletes will have better academic performance than non-athletes. Gender, type of\nschool, social economic status (SES), Kenya Certificate of Primary Education\n(K.C.P.E.) marks and participation in competitive sports were used as independent\nvariables, while academic performance was regarded as the dependent variable. Data\nwere collected from 490 subjects randomly selected from 15 secondary schools within\nNairobi Province of Kenya. Questionnaires, interviews and school records were used\nfor data collection. Data were analysed through MANOVA and Tukey H.SD. tests.\nFindings revealed that athletes consistently performed better than non-athletes. It was\nalso found that SES, K.C.P.E. and type of school correlated positively with academic\nperformance while sex did not. It was recommended that competitive sports be\nemphasized in secondary schools because it is not detrimental to academic performance. en_US", "pred_label": "__label__POS", "pred_score_pos": 0.7421057224273682}
{"content": "Over the past few decades, research has shown how the gut can impact your overall health and wellbeing. Gut health plays a role in your mood, vibrant skin, heart health, and even your weight.[1]\nUnderlying gut health is trillions of bacteria, which reside within the gut. These bacteria play critical roles in many processes, including digestion and immunity.[2] A wall keeps the gut intact. This thin layer of cells forms the first physical barrier that separates the contents of the gut from the bloodstream.\nThis gut barrier allows nutrients to cross into the bloodstream while preventing potentially harmful small molecules and organisms from leaving the gut. Proteins called\ntight junctions to form a “glue” that keeps these cells sealed.[3] What is Leaky Gut?\nA healthy gut depends on the correct balance between favorable and unfavorable bacteria. When that balance becomes disrupted, a condition called\ndysbiosis results.\nThis imbalance between favorable and unfavorable bacteria can loosen up the tight junctions that keep the gut wall intact. Harmful substances can then leak into the bloodstream, creating\nincreased intestinal permeability or leaky gut.[4]\nThese particles –– partially digested food but also things like toxic digestive metabolites and bacterial toxins –– can then travel throughout the body, even slipping into the brain.\nNumerous things can disrupt the balance of gut bacteria and make the gut wall “leaky,” including:\nThe standard American diet, which is low in fiber and high in sugar Alcohol Non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen [5] Chronic stress [6] Over-using antibiotics [7] Infections such as Helicobacter pylori, a bacterium that infects the stomach [8] Environmental toxins How the Body Responds to Leaky Gut\nLeaky gut can create gut-related conditions including celiac disease, Crohn’s disease, and irritable bowel syndrome. These repercussions go beyond the gut, impacting the entire body. Among those reactions include:\nAn immune response.The immune system doesn’t recognize these partially digested food particles and other things that slip through the gut wall, so it attacks them. Chronic inflammation.As the immune system stays fired up, inflammation simmers. Over time, chronic inflammation can impact your entire body and contributes to nearly every disease.[9] [10] Food sensitivities.Imbalances in gut bacteria can create food sensitivities, where specific foods can trigger a reaction with bloating, gas, diarrhea, abdominal pain, and nausea.[11] Autoimmune disease.Particles that slip into the bloodstream can lodge in specific areas, such as joints. The immune system can mistakenly attack these tissues, which can lead to autoimmune diseases.[12]\n“All disease begins in the gut,” Hippocrates said about 2,500 years ago. What impacts the gut can go on to impact the entire body, including the brain. Scientists have connected leaky gut with conditions including autistic spectrum disorder, dementia, depression, schizophrenia, and other brain disorders.\nLeaky gut can play a role in a wide range of diseases, including diabetes and obesity.[13] It can even impact sleep by inhibiting the production of melatonin, a hormone that regulates circadian rhythm.[14]\n5 Ways to Support Gut Health\nWhat you eat and how you live can dramatically impact gut health. While leaky gut and other gut conditions sometimes require working with a healthcare practitioner, these five strategies can support the right balance of gut bacteria and keep the gut healthy.\nEat gut-supporting foods.Foods rich in probiotics support the growth of healthy gut bacteria. Kimchi, sauerkraut, and unsweetened Greek yogurt are excellent probiotic-rich foods. Leafy and cruciferous vegetables, low-sugar fruits like berries and avocados, and nuts and seeds provide dietary fiber, including prebiotic fiber, which feeds probiotics.[15] Our Advanced Planeliminates gut-unfriendly foods and incorporates anti-inflammatory, gut-healing foods. Try an elimination diet.If you suspect food sensitivities could be contributing to leaky gut, consider a short-term elimination diet, where you remove a particular food or foods for two to four weeks and see if your symptoms improve. If you reintroduce that food and symptoms reappear, you know what could be creating these problems.[16] Manage stress levels.The wide-ranging impact of chronic stress impacts nearly every aspect of health, including the gut. Learn 16 ways to manage stress here. Minimize Toxins.A good place to begin minimizing the pesticides and other toxins that contribute to leaky gut is with your food. The Environmental Working Group (EWG) provides a Shopper’s Guide to Pesticides in Produce. Make more informed cosmetics choices with the EWG’s Skin Deep®guide. Avoid harsh cleaning chemicals and save money with natural cleaning solutions. Get the right nutrient support.Probiotics reinforce the intestinal barrier by increasing tight junction proteins and supporting other intestinal cells. These living organisms maintain the balance of gut bacteria and suppress the growth of harmful bacteria. Probiotics also support the immune cells within the gut.[17]\nA probiotic supplement makes a convenient, effective way to get beneficial amounts of the healthy gut flora that helps restore the balance of gut bacteria and supports overall gut health. That’s why we created\nProbiotic 50B.\nThis broad-spectrum formula contains a diverse blend of the most highly-researched probiotics to support a healthy gut, immune system, and more in just one easy-to-swallow capsule daily.\nWhen it comes to buying probiotic supplements, quality matters. These supplements are\nliving organisms that have many barriers to cross, including shelf life and surviving the acidic conditions of the stomach. Probiotic 50B delivers a powerful blend of healthy gut bacteria in a moisture-resistant capsule featuring delayed-release technology. This ensures the capsule delivers all of the healthy bacteria to support a healthy gut, immune system, and so much more. Our capsules are non-GMO, dairy-free, and gluten-free. Never modify or discontinue any medication without the consent of your healthcare practitioner. References", "pred_label": "__label__POS", "pred_score_pos": 0.8432984948158264}
{"content": "The lesson is that diversification does matter and to think otherwise is foolish. Even though the Dow Jones Industrial Average and the S&P 500 continue to blow through historical highs, establishing and maintaining a defensive barrier (i.e., fixed income) is still critical in a well-managed portfolio.\nYes, I understand it may sometimes be tempting to put all your eggs in one basket after this year’s performance in the equity markets, especially domestic. However, without a crystal ball it is impossible to guess which asset class will lead the race in 2014.", "pred_label": "__label__POS", "pred_score_pos": 0.9797266721725464}
{"content": "Abstract\nMonocytes and dendritic cells (DCs), mononuclear phagocytes essential for immune responses, develop from hematopoietic stem cells via monocyte-DC progenitors (MDPs). The molecular basis of their development remains unclear. Because promoter-distal enhancers are key to cell fate decisions, we analyzed enhancer landscapes during mononuclear phagocyte development in vivo. Monocyte- and DC-specific enhancers were gradually established at progenitor stages before the expression of associated genes. Of the transcription factors predicted to bind to these enhancers, IRF8, essential for monocyte and DC development, was found to be required for the establishment of these enhancers, particularly those common to both monocyte and DC lineages. Although Irf8\n–/– mononuclear phagocyte progenitors, including MDPs, displayed grossly normal gene expression patterns, their enhancer landscapes resembled that of an upstream progenitor population. Our results illustrate the dynamic process by which key transcription factors regulate enhancer formation and, therefore, direct future gene expression to achieve mononuclear phagocyte development. The regulation of enhancer dynamics during postnatal mononuclear phagocyte development remains unclear. Kurotaki et al. analyze the enhancer landscape during monocyte and dendritic cell development in vivo. Enhancers are gradually established by transcription factors such as IRF8 at progenitor stages before the expression of associated genes, defining the progenitors’ differentiation potential. Keywords ChIP-seq IRF8 dendritic cell development enhancer monocyte transcription factor ASJC Scopus subject areas Biochemistry, Genetics and Molecular Biology(all)", "pred_label": "__label__POS", "pred_score_pos": 0.5080724358558655}
{"content": "Brand: NOW Features: Publisher: NOW Details: Cascara Sagrada Capsules from NOW® Foods is an egg-free product that may support your digestive tract. This soy-free supplement could cleanse your colon and regularize bowel movements. Cascara sagrada present in this supplement from NOW® Foods is an herb‚ rich in compounds called anthroquinones that could stimulate the smooth muscle in the large intestine and make them contract. They might increase bowel volume by preventing the absorption of water in the intestine. Bowel habits could vary from person to person and some people may experience difficulty in passing stool. Various factors could impair bowel activity and lead to infrequent movements‚ which could be uncomfortable or even painful. Cascara might possess anti-bacterial powers‚ thereby promoting the immune health of your intestine. It could also improve the tone of the intestine. Improve your digestive health and strengthen your intestine with Cascara Sagrada Capsules from NOW® Foods. These statements have not been evaluated by the Food and Drug Administration (FDA). These products are not meant to diagnose� treat or cure any disease or medical condition. Please consult your doctor before starting any exercise or nutritional supplement program or before using these or any product during pregnancy or if you have a serious medical condition. UPC: 733739046239 EAN: 0733739046239 Package Dimensions: 4.9 x 2.9 x 2.7 inches Binding: Health and Beauty Item Condition: New", "pred_label": "__label__POS", "pred_score_pos": 0.5707989931106567}
{"content": "Commerce The Commerce Department at Camberwell Girls is committed to implementing innovative teaching and learning strategies that focus on each student’s ability to understand how to navigate and make sense of our major financial, legal, economic and business institutions.\nCommencing with a range of Middle School subjects that focus on developing financial literacy in students including Being a Global Economic Citizen, Going into Business, The Law and You and Financial Literacy for the Consumer, Commerce then moves to a full range of Senior School VCE offerings.\nIn these subjects, students are encouraged and empowered to develop the skills required to recognise and understand how key institutions integral to our society operate. By developing and maintaining direct contact with government and private businesses, students are equipped with the knowledge to assess and compare actual practices with contemporary theory, preparing them to become tomorrow’s decision makers.\nSpecialised curriculum areas in the VCE program include: Accounting Business Management Economics Legal Studies\nIn the IB Program, Economics and Information Technology in a Global Society (ITGS) are popular options.", "pred_label": "__label__POS", "pred_score_pos": 0.9847848415374756}
{"content": "Many individuals in Oregon and across the country consider their financial future to be of the utmost importance. When facing substantial monetary hardships, one who wishes to protect this area of life may subsequently wonder about the available options for relief. For those who consider Chapter 7 bankruptcy, there are several factors that may influence their decision, and seeking guidance could prove beneficial to navigating the process.\nPerhaps one of the most intimidating aspects of a Chapter 7 bankruptcy involves the liquidation of assets. While this type of bankruptcy does call for liquidation, this doesn’t necessarily include all of one’s belongings. Certain assets may be exempt from the process, and gaining an understanding of federal and Oregon state bankruptcy laws could help an individual make informed decisions regarding his or her financial future.\nBy liquidating assets through a Chapter 7 bankruptcy, many of a person’s debts may be discharged in the process. However, not all debts are eligible for forgiveness, such as those pertaining to student loans and child or spousal support. Obtaining guidance on how filing for bankruptcy will impact one’s assets and debts could prove crucial to determining the correct path with which to seek relief.\nWith numerous crucial factors to consider regarding one’s financial future, an individual may find it beneficial to seek counsel in the initial stages of the process. By speaking with a bankruptcy attorney, a client in Oregon could obtain some much-needed advice on every available option for relief, as well as their potential outcomes. An attorney can thoroughly evaluate a client’s financial situation and provide advice on how to pursue the most favorable outcome through the necessary channels.\nSource: mpnnow.com, “John Ninfo: The basics of a consumer bankruptcy“, John Ninfo, Aug. 29, 2017", "pred_label": "__label__POS", "pred_score_pos": 0.9644483923912048}
{"content": "Sweeping Tax Relief Provisions included in the CARES Act (Individual Provisions)\nApril 1, 2020\nIn an effort to help businesses and individuals weather the economic storm created by the coronavirus shutdowns, the Coronavirus Aid, Relief, and Economic Security (CARES) Act, which Congress passed and the President signed on March 27, included many provisions easing restrictions imposed by the Internal Revenue Code. Key changes relating to Individual taxpayers are highlighted below. Changes oriented toward businesses have been covered in a separate Alert. Recovery rebates for individuals. To help individuals meet financial needs during this time of crisis, the federal government will send up to $1,200 to eligible single taxpayers and $2,400 to married couples filing joint returns. An additional $500 payment will be sent to taxpayers for each qualifying dependent child under age 17. For individual taxpayers with adjusted gross income (AGI) over $75,000, joint filers with AGI over $150,000 and head of household filers with AGI over $122,500, the payment amount is phased out, at a rate of 5% of the amount exceeding this threshold. Under these rules, the rebate is completely phased-out for a single filer with AGI exceeding $99,000, for a joint filer with no children with AGI exceeding $198,000, and for a head of household with one child, with AGI exceeding $146,500. Most individuals will not have to take any action to receive a rebate. IRS will compute the rebate based on a taxpayer’s 2019 tax return (or 2018, if the 2019 return has not yet been filed). Note that rebates are payable whether or not any tax was owed on the 2019 (or 2018) return. Waiver of 10% early distribution penalty. Recognizing that individuals may need to turn to their IRAs and other retirement plans for funds to help them through the crisis, the CARES Act waives the 10% penalty tax on early distributions from IRAs and defined contribution plans (such as 401(k) plans) for any person who (or whose family) is infected with the coronavirus or who is economically harmed by the pandemic. This relief applies to anyone (i) who is diagnosed with the coronavirus by a test approved by the Centers for Disease Control and Prevention, (ii) whose spouse or dependent is diagnosed with coronavirus by such a test or (iii) who experiences adverse financial consequences as a result of being quarantined, furloughed or laid off or having work hours reduced due to the pandemic, being unable to work due to lack of child care due to the coronavirus, closing or reducing hours of a business owned or operated by the individual due to the coronavirus, or other factors as may be specified by the Secretary of the Treasury. Penalty-free distributions are limited to $100,000, and may be re-contributed to the plan or IRA at a later time. Income arising from the distributions is spread out over 3 years unless the taxpayer elects otherwise. Employers are permitted to amend defined contribution plans to provide for these distributions. Additionally, defined contribution plans are permitted more flexibility in the amount and repayment terms of loans to employees affected by the coronavirus and attendant economic distress. Waiver of required distribution rules. Required minimum distributions that otherwise would have to be made in 2020 from defined contribution plans (such as 401(k) plans) and IRAs are waived. This includes distributions that would have been required by April 1, 2020, due to the account owners reaching the age of 70 1/2 in 2019. Charitable deduction liberalization. The CARES Act allows an individual taxpayer to take a $300 above-the-line deduction for cash contributions made, generally, to public charities in 2020. This rule overrides the limitation imposed by the 2017 tax act barring charitable contribution deductions for taxpayers filing with the standard deduction. An individual taxpayer’s ability to claim itemized deductions for charitable deductions in any year has been subject to a ceiling equal to 60% of the taxpayer’s modified adjusted gross income for the year. The CARES Act removes this limitation for cash contributions made, generally, to public charities in 2020. For both of these changes, no connection needs to be shown between the contributions and the impact of the coronavirus. High Deductible Plan Remote Care Services. The CARES Act allows high deductible health plans to pay for expenses in 2020 for tele-health and other remote health care services without regard to the deductible amount for the plan. Nonprescription Medical Products. For amounts paid after December 31, 2019, the CARES Act allows amounts paid from Health Savings Accounts and Archer Medical Savings Accounts to be treated as paid for medical care even if they are not paid under a prescription.\nE\nxclusion for employer payments of student loans. An employee currently may exclude $5,250 from income for benefits from an employer-sponsored educational assistance program. The CARES Act expands the definition of expenses qualifying for the exclusion to include employer payments of student loan debt made before January 1, 2021. MORE INFORMATION\nThe contents of this Alert are for informational purposes only and do not constitute legal advice. If you have any questions about this Alert, please contact the Shulman Rogers attorney with whom you regularly work or a member of the Shulman Rogers Tax Law Group.", "pred_label": "__label__POS", "pred_score_pos": 0.6907390356063843}
{"content": "At first glance the question, \"what do I want?\" seems to be about having something. I want some cake, I want a holiday, I want a job, I want a partner and so on. Thinking along those lines isn't floating my boat, or making me excited about the possibilities.\nInstead, if I focus on how do I want to feel, then it gets more interesting.\nWay back, when I was in my early 30's and suffering with depression, I recall often saying \"I just want to be happy\". I didn't get any more specific than that. And, it seemed elusive. Happiness.\nToday, as I ponder on how I want to feel I have already disappeared down a rabbit hole of investigating the difference between emotions and feelings. Seems emotions are physical and instinctive, whilst feelings are sparked by emotions and influenced by life experience, beliefs and thoughts. Maybe this is a distraction from the task in hand!\nWhen I think about how I want to feel what emerges is wanting to know that I matter.\nI want to feel excited about the day ahead when I wake up. I want to feel challenged and stretched, but not too much. I want to test out my edges, and discover what is possible.\nBut, the essential container for all of this is the feeling of being connected, of being a part of something bigger than myself, and knowing that my contribution matters (whatever it is). I want to feel included, to feel a part of something, to feel my contribution is significant (as in it matters, not that it's huge!).\nThis feels like work in progress. To be reflected, and slept on.\nAlmost done…\nWe just sent you an email.\nPlease click the link in the email to confirm your subscription!", "pred_label": "__label__POS", "pred_score_pos": 0.8935670852661133}
{"content": "Valuable lessons can be learned from smallholder farmers who have successfully protected and regenerated tree cover across agricultural landscapes in Senegal, with minimal reliance on tree nurseries, seedling distribution or tree planting. In the process, they have restored soil fertility to sustainably increase agricultural production. Analysing how and where this approach has occurred underscores the importance and feasibility of achieving restoration in ways that contribute to improved livelihoods, reduce vulnerability to climate change and other shocks, and restore ecosystem services. This article highlights a relatively low-cost intervention implemented by rural communities with support from development organizations.\nThis article was submitted for inclusion in the forthcoming edition of ETFRN News 60 - Restoring African drylands, due for release in December 2020, containing 25 articles plus interviews and boxes describing farmer-led, NGO, private sector, government and international initiatives. These highlight the roles of varied policies and stakeholder interests, and identify opportunities to encourage smallholder and community participation in scaling out successes and meeting national, regional and global commitments.", "pred_label": "__label__POS", "pred_score_pos": 0.9943934082984924}
{"content": "Future higher temperatures in the Norwegian Arctic, including the Barents Sea, will likely cause several pathogens (parasites, bacteria, viruses) to extend their distributions northward (Tryland et al., 2009). The prevalence and abundance of pathogens may also change. Such a change in distribution of pathogens may have several consequences for both wild and domesticated animals, which are difficult to predict due to a lack of data.", "pred_label": "__label__POS", "pred_score_pos": 0.6028529405593872}
{"content": "As a savvy eCommerce business, you’re fully aware that website performance matters in the digitized, instant-gratification world in which we live. Improved web performance impacts an increase in pages viewed, products viewed, cart conversions, and revenue.\nTake a moment to consider this – 53% of mobile users abandon sites that take longer than 3 seconds to load, according to a recent study from Google. Website performance is linked to the scalability of your commerce platform during periods of high traffic volumes, such as the holiday shopping season. (As a side note, retail websites saw record volumes of eCommerce sales during the 2016 holiday season.) It’s no wonder then that 74% of online retailers are concerned their existing platforms won’t scale for future growth, which brings up the question: How do you determine the scale and capacity to support your eCommerce business?\nSimply stated – it’s a blend of art and science. You need a strategy that accounts for seasonality, special promotions or campaigns, and cyber holidays. These elements contribute to increased traffic and sales spikes compared to the daily ebb and flow of your online business.\nUnderstanding the technical architecture of your current platform and key performance indicators (KPIs) that drive your online business will introduce a data-driven approach to calculate scalability requirements. As you consider commerce platforms and their supporting technical architecture, make sure you address these questions: What is the best hosting option for the platform and supporting platform integrations based on your current and future business needs? How will the platform’s performance be maintained as site traffic and order volumes increase? What disaster recovery and/or high availability options exist in the event of infrastructure failure?\nWhen considering the hosting environment, the most common options include:\nCloud\nThe advantages of cloud include its massive scalability and pre-configured or customizable environments that reduce hardware and management burdens for IT. Based on your business needs and budget, you can opt for a lower-cost public cloud, or choose a private cloud that ensures your networks are secure and compliant.\nOn-Premises\nThe benefit of this option is that you have complete control of the hardware, security, performance, and scale. However, this places the operational and fiscal responsibility for the eCommerce infrastructure on the shoulders of your IT team.\nHybrid\nThis environment provides the advantages of cloud and on-premises hosting – dedicated hardware to remain secure and compliant with the performance efficiencies of cloud. You can control critical systems and data in your on-premises environment while moving certain workloads, such as email or content delivery, to the cloud.\nIf you’re considering a Software-as-a-Service (SaaS)-based commerce platform, the infrastructure is typically provided as part of the service. However, you should still ask the same questions to ensure that the platform will scale for your anticipated growth. To learn more, download our latest guide – Best Practices for Choosing a Commerce Platform, Part 2 – where we explore the top three considerations for evaluating digital commerce platforms and illustrate how we’ve helped clients successfully launch their eCommerce re-platforming projects.", "pred_label": "__label__POS", "pred_score_pos": 0.9638798236846924}
{"content": "BACKGROUND: Premedical students often elect advanced science courses whose content will reappear during preclinical courses. Are such “preludes” useful? METHOD: The study participants were the 176 first-year students entering the University of Iowa College of Medicine in 1992. Their grades in medical school courses in biochemistry, gross anatomy, histology, physiology, and microbiology were compared with their grades in similar premedical courses. RESULTS: The students who had taken a premedical prelude in advanced science performed no better than their classmates except in biochemistry, where the 118 students (67%) with prior biochemistry exposure had a significantly higher mean score (96.3 vs 87.6, p < .0001 using Student's t-test). A biochemistry prelude appeared to benefit all students, especially those from minorities underrepresented in medicine. In addition, among the 13 students who failed biochemistry in medical school, a number of them had low grades in organic chemistry and had not taken a premedical course in biochemistry. To test the replicability of the findings, an analysis was undertaken of the biochemistry performances of the 162 students who had entered in 1991, and again a significant difference was found between the students who had and those who had not taken a biochemistry prelude. CONCLUSION: A premedical biochemistry course, required by only two schools in 1995-96, appears advantageous, especially for students with weak academic preparation. Lack of such benefit from other preludes suggests that premedical students might better choose electives in arts and humanities to enhance their educational breadth.\nCreated Date: 16 May 1997; Completed Date: 16 May 1997; Revised Date: 18 December 2000\n© 1996 Association of American Medical Colleges", "pred_label": "__label__POS", "pred_score_pos": 0.9569710493087769}
{"content": "Introduction: Transmedia Practices: A Television Branding Revolution Abstract\nThe television world is changing, having been impacted by mutations of three different natures: technological, narrative and participatory. Productions now use technology to enhance their content as television series and movie franchises are, increasingly, basing their narratives on principles of narrative complexity since active audiences do not only consume, but also engage with the said texts. These efforts made by the industry to target involved audiences demonstrate how transmedia practices have impacted not only on storytelling processes, but the text – and\nbrand – itself, the latter no longer being a mere programme with a limited duration, but a whole, composed of numerous elements spread across media. The goal of the different players involved is, nevertheless, quite different. While fans’ activities represent a way to empower themselves and engage with this universe, the teams behind institutional transmedia strategies seek to secure more (faithful) customers and, incidentally, a higher financial return.\nRather than reducing transmedia storytelling to the augmenting effect it had on the concept of narrative resulting from its ability to create an immersive environment, this issue seeks to discuss the wide range of economic perspectives available to film and television brands due to this very immersive environment. The transmedia phenomenon has, so far, mostly been approached from an either textual or participatory standpoint, but rarely so from a multidisciplinary perspective encompassing the marketing aspect. Providing insight on this topic – so far not discussed in\nNetworking Knowledge – through contributions from researchers in media, communications, cultural studies and marketing, the issue seeks to enrich our collective understanding of transmedia practices, in the hope of offering a more holistic approach. In doing so, the various pieces presented in this edition clearly demonstrate that transmedia practices have revolutionised television branding.. and that it’s just getting started. Networking Knowledge: Journal of the MeCCSA Postgraduate Network, 7(1). https://doi.org/10.31165/nk.2014.71.326", "pred_label": "__label__POS", "pred_score_pos": 0.5903372764587402}
{"content": "Habits are best made when we are young. It is essential to relate what children learn in school to their real-life activities. Each activity we do in school has an objective and is a ‘’teachable moment’’ for our students.\nKG students had a unique activity for table manners and etiquette, as reinforcing these manners is a crucial part of the everyday meal for kids. Children had many activities on that day. They pretended that their classroom is a restaurant with a creative restaurant name. They baked pizza and cupcakes with their teachers and modeled good table manners!!!\nWell done, KG students!!!", "pred_label": "__label__POS", "pred_score_pos": 0.9970899820327759}
{"content": "As more states implement specific Medicaid reimbursement practices for immediate postpartum long-acting reversible contraception (LARC) such as intrauterine devices (IUDs) and implants, researchers from the University of Michigan Health System have identified challenges for agencies and providers alike in a study published in\nContraception.\nMichelle Moniz, MD, MSc, an assistant professor of obstetrics and gynecology and researcher at the University of Michigan Medical School, and colleagues conducted semistructured phone interviews with Medicaid representatives in 39 states, 13 of which have specific payment practices for immediate postpartum LARC devices, on agency goals for immediate postpartum LARC method reimbursement and administrative- and provider-level experiences with policy implementation.\nMajor themes that emerged included difficulties by the agency in promoting beneficiaries’ well-being and improved access to LARC methods and provider mistrust of the agency regarding payment. Focusing on on ensuring that claims were paid and reimbursement rates sufficiently addressed clinical costs of LARC methods was also discussed in the interviews. Many expressed struggles with notifying providers effectively about inpatient method coverage and mixed reactions from providers on offering immediate postpartum LARC methods vs. concerns about potential patient harm and insufficient technical expertise. The representatives expressed concerns over limited or no resources for clinical implementation or evaluation for their primary roles as eliminating reimbursement barriers.\nContinue Reading\n“Many women’s first choice for birth control is an IUD or implant, which we know are the safest and most effective forms of reversible contraception. The problem is that many postpartum women can’t make it back to the office for an appointment to get one,” said Dr. Moniz. “Our findings suggest that more and more agencies recognize significant benefits to providing this service before women even leave the hospital.” The authors are optimistic that as more Medicaid programs cover immediate postpartum LARC methods for timely contraception, opportunities will emerge for discussing these and other barriers. Eight additional states are currently considering immediate postpartum LARC insertion reimbursement.\nFor more information visit med.UMICH.edu.", "pred_label": "__label__POS", "pred_score_pos": 0.8174892663955688}
{"content": "by Diana Guo (MLA I '21), Runke Luo (MLA I AP '21), and Yuning Zhang (MLA I '21) — Winner of a 2020 Applied Arts Award\n“Snow Bank” is a multi-scalar, community-based response to reuse snow for district cooling in East Boston by extending the lifetime of winter snow to be used during the extreme heat of summer. On the regional scale, snowstorms are growing more unpredictable in intensity as the climate changes while hot summers are increasingly unbearable. On the local community level, neighborhoods must come up with a rapid snow management plan that clears roads efficiently to allow equitable access to public transportation and protect their hydrological systems from severe snow meltwater contamination.\nWe seek to redefine the public commons through shared responsibility and redistribution of snow from a state of urban waste to one of valuable resource. Our team proposes an acupunctural network of snow storage inserted into the landscape that collect snow during cold seasons and emit cool air in the summer. The insertions correspond with above-surface landscapes that offer alternative spaces of public gathering and recreation. While each move is acupunctural, the larger effect becomes visible as a new shared commons emerges from the city fabric.", "pred_label": "__label__POS", "pred_score_pos": 0.8368574976921082}
{"content": "The interconnected world provides us with untold opportunities and conveniences. From shopping online to e-banking to something as simple as ordering a pizza, all made possible by the internet. However, these conveniences do not come risk-free, the internet also has a darker side. It is predicted that cybercrime could cost the global community up to £5.4 trillion annually by 2021. However, not every part of the world is equally exposed to cyberattacks, which then poses the question: How exposed is the UK?\nThe UK government’s ongoing initiatives and measures to combat cybercrime plays a key role in its recent rank as the 13th least exposed country to cyberattacks globally, as well as making the top ten cut in Europe, placing 8th. Whilst those who reside in the UK can breathe a sigh of relief, this doesn’t mean the UK is immune.\nThe biggest threats faced by the UK\nHacking techniques that leverage either stolen credentials or known vulnerabilities dominate the types of attacks across EMEA.\nAccording to Verizon’s 2020 Data Breach Investigations Report, 42 percent of web application data breaches are caused by stolen credentials, whereby the attacker gathers compromised login details either through phishing or malware to then gain access to an online account or platform. Unsurprisingly, 56 percent of the data exposed in data breaches falls into the credentials category, elevating the importance of protective software.\nMost notably, 2020 saw cybercriminals target outward-facing email servers, as well as business-critical applications.\nIncidentally, 27 percent of malware incidents were ransomware, which Cybersecurity Ventures predicts will cause damage costs of £16 billion by 2021, equating to 57X more than it was in 2015 – making it the fastest-growing type of cyberattack.\nThe second tactic used – exploiting vulnerabilities – accounts for 20 percent of breaches in EMEA, where an attacker gains access to data or a system or repurposes a server for malicious intent. Checking external-facing websites or software for vulnerabilities, as well as missing security protocols, such as multi-factor authentication, is key to minimise your exposure.\nSurprisingly, it’s not just external threats you should be worried about but also internal. Internal actors account for 13 percent of all data breaches with 70 percent of all threat actors driven by financial gain, followed by espionage (22 percent).\nWhere do the cyberattacks originate From?\nSince the very nature of cybercrime transcends international borders, cyber actors often mask their identity to remain completely anonymous which can make it difficult to identify those responsible for attacks. However, it has been reported by the National Cyber Security Centre that a significant number of incidents come from hostile nation-states.\nOne such example involved the infamous group Turla. Turla hijacked the systems of a rival Iranian APT (advanced persistent threat) allowing them to masquerade as Iranian hackers to cover their Russian origin while they executed malware attacks against UK entities.\nMore recently, the Lazarus Group, commonly believed to be run by the North Korean government, planned a large-scale campaign sending COVID-19-themed phishing emails to over 5 million businesses and individuals across six countries, including the UK.\nThe UK’s resilience to cyberattacks\nThe UK has the highest level of commitment to cybersecurity globally thanks to the three core objectives of the National Cybersecurity Strategy:\nDefend – Protect networks, data, and systems by ensuring that the UK can defend against new waves of cyberthreats, respond effectively to incidents, and provide citizens, businesses, and the public sector with the knowledge needed to employ the necessary security protocols. Deter – Make the UK a hard target by meticulously detecting, understanding, investigating, and disrupting all hostile actions taken against us, whilst also rigorously pursuing and prosecuting offenders. Develop – A combination of continued innovation through world-leading scientific research and development and maintaining a pipeline of talent to fill the skills needed to meet both the public and private sector needs will enable the UK to adeptly overcome the threats of an ever-changing cyber environment.\nThe UK is a prosperous digital nation and it will continue to attract the attention of attackers but with the £1.9 billion invested to defend, deter, and develop against cybercrime, the UK’s level of commitment to cybersecurity is set to stay at the top of the pack globally. However, global cooperation is required to make the digital world a safer place.\nContributed by Joshua Frisby, Founder of PasswordManagers.co.", "pred_label": "__label__POS", "pred_score_pos": 0.5745518207550049}
{"content": "There is no feeling like seeing the face of a student reaching an \"ahh haa\" moment in math class. After teaching middle school mathematics for almost ten years, I was eager to begin a journey of supporting my fellow classroom math teachers as our district’s mathematics coach. In this role, I have been able to continue to engage in one of my passions-connecting research to classroom practices. I am excited to serve the members of NCSM as the associate journal editor.\nMember Story\nI was deep into my 3rd year as the elementary mathematics coach for my school district, when a colleague approached me with an interesting opportunity to attend a leadership institute in Atlanta, GA. Little did I know that this institute would change my life. After attending NCSM’s Winter Leadership Institute that December, I knew I had found the place with \"my people\". Being able to collaborate, problem-solve, and celebrate with the people who understood the struggles, and the joy behind the celebrations, re-energized my quest in supporting our district’s mathematics teachers. From the \"Coaching Corner\" to NCSM’s position papers, I have found the guidance I need to be an effective mathematics coach.", "pred_label": "__label__POS", "pred_score_pos": 0.6066372394561768}
{"content": "Despite weaknesses, the new sub-compact SUV has the potential to bring the Japanese car maker back into the ...\nMCX-Natural Gas ( ₹127 )\nThe rally that the August futures contract of natural gas on Multi Commodity Exchange (MCX) was witnessing hit a roadblock at the resistance level of ₹150 in early July. Unable to move beyond that level, the contract reversed the trend immediately and started to fall. The decline has been quick where the contract is now trading around ₹127. Visibly, there is no support until its previous low of ₹121.4, meaning there is more room on the downside.\nCertain factors substantiate the bearish outlook. For instance, the price has slipped below the 21-day moving average (DMA) and the Relative Strength Index (RSI) and the Moving Average Convergence Divergence (MACD) indicators on the daily chart remains in their respective bearish territory. Considering these factors, the likelihood of further fall seems high.\nWhile ₹121.4 can be the nearest support, a decisive breach of this level can invite more bears, possibly resulting in more intense downtrend. The price could even fall to ₹110. On the other hand, if the contract recovers and moves up, ₹130 can be a hindrance. Above that level, the resistance can be spotted at ₹135; the 21-DMA and the 50 per cent Fibonacci retracement level coincides at this level making it a significant resistance.\nOn the global front, the generic first contract of natural gas on New York Mercantile Exchange (NYMEX) made a high of $1.92 in the first week of July. However, it was unable to advance further and started to moderate. Last week, it breached the support of $1.7 and the contract looks set to depreciate further.\nTrade Strategy:\nThe contracts on MCX and NYMEX has been in a decline since early July after having rallied during the preceding two weeks. Notably, the major trend of the energy commodity remains bearish, increasing the possibility of further decline in price. Hence, traders can go short in MCX-Natural gas on rallies with stop-loss at ₹135.", "pred_label": "__label__POS", "pred_score_pos": 0.9417065978050232}
{"content": "The Department of Health and Human Services (HHS) issued guidance to hospitals and clinics reminding them that they must still comply with patient privacy rules during the COVID-19 crisis. In light of media focus, it is particularly important for providers to obtain a valid health privacy authorization from each patient whose protected health information would be accessible to the media. This requirement applies even if footage uses pixilation, blurring, or alteration for patients’ faces or voices.", "pred_label": "__label__POS", "pred_score_pos": 0.9979439973831177}
{"content": "The concept of “connectedness with nature” is increasingly used in environmental and sustainability discourse. However, this construct has also ...On March 24, 2019 / By eyes4earth\nSoul is the price we have paid for our civilization.\neyes4earth.org is a portal into meaningful nature experience and connectedness with nature. It draws on scientific research and experiential insight to explore implications for sustainability education and consciousness.\nLearn more »", "pred_label": "__label__POS", "pred_score_pos": 0.9988781213760376}
{"content": "Far too often, youths are being prescribed powerful antipsychotics “off-label”, or for a different use than the drug was initially intended. Researchers report that for those under 18 of normal intelligence, there’s no indication that the drugs have any positive effect. As Sharon Kirkey reports for the Ottawa Citizen, presciption medication designed for schizophrenia, for…Read", "pred_label": "__label__POS", "pred_score_pos": 0.7960677146911621}
{"content": "Abstract\nThe Transmembrane BAX Inhibitor Motif containing (TMBIM) superfamily, divided into BAX Inhibitor (BI) and Lifeguard (LFG) families, comprises a group of cytoprotective cell death regulators conserved in prokaryotes and eukaryotes. However, no research has focused on the evolution of this superfamily in plants. We identified 685 TMBIM proteins in 171 organisms from Archaea, Bacteria, and Eukarya, and provided a phylogenetic overview of the whole TMBIM superfamily. Then, we used orthology and synteny network analyses to further investigate the evolution and expansion of the BI and LFG families in 48 plants from diverse taxa. Plant BI family forms a single monophyletic group; however, monocot BI sequences transposed to another genomic context during evolution. Plant LFG family, which expanded trough whole genome and tandem duplications, is subdivided in LFG I, LFG IIA, and LFG IIB major phylogenetic groups, and retains synteny in angiosperms. Moreover, two orthologous groups (OGs) are shared between bryophytes and seed plants. Other several lineage-specific OGs are present in plants. This work clarifies the phylogenetic classification of the TMBIM superfamily across the three domains of life. Furthermore, it sheds new light on the evolution of the BI and LFG families in plants providing a benchmark for future research.\nKeywords Bax inhibitor 1 Gene family evolution Lifeguard Programmed cell death Synteny network TMBIM", "pred_label": "__label__POS", "pred_score_pos": 0.6363335847854614}
{"content": "n August 2020, the National Institute for Learning Outcomes Assessment (NILOA) released survey findings examining assessment-related changes made in the Spring 2020 semester. As part of that report, we examined the intersections of those findings with other COVID-19 related reports on the shift to remote instruction and students’ experience of teaching and learning during that time, offering considerations for practice in the fall and beyond. While August was only a month ago, in pandemic time it feels like at least 8 months have passed since the report was released. Based on conversations with assessment professionals and questions raised about learning in the fall, the report remains relevant all this time later.", "pred_label": "__label__POS", "pred_score_pos": 0.9140476584434509}
{"content": "The Story of Meg Quinn\nAfter 44 seasons, Theatre of Youth (TOY) continues to provide innovative and professional theatre for child audiences. Today, it resides in Buffalo's historic Allendale Theatre as a destination for the community's youth to engage with dramatic experiences crafted just for them. Artistic Director Meg Quinn discussed how the theatre's mission has successfully connected with schools and families in the community.\n\"Anyone can jump up and down to entertain kids and have fun,\" said Quinn. \"We have always tried to take a bigger, greater responsibility for the children of our community.\"\nThis focus began in 1972, when Daemen College theatre professors Rosalind Cramer and Toni Smith Wilson attended an international conference of children theatres in Albany, NY. They were inspired by thought-provoking performances created specifically for child audiences, from theatres all over the world. Cramer and Smith Wilson brought this vision back to Buffalo and established Theatre of Youth with a group of several undergraduate students, including Quinn. TOY's programming today includes carefully selected plays that resonate across a range of age groups. Quinn notes that these plays share a common goal of having something important and authentic to say.\n\"Through these stories, we want to show children that some of life's difficult decisions take courage and can change the world,\" said Quinn. \"It gives them a lot to think about. That's our purpose.\"\nQuinn notes that selecting each season's performances is among her toughest and most important responsibilities. While TOY is committed to serving the development of Buffalo's youth, the selection process is highly collaborative across the country. Quinn communicates with artistic directors at professional children's theatres in Boston, Dallas, Kansas City, Minneapolis, Washington, D.C., and other cities to share scripts, discuss trending titles and share new information about research in creativity and child development.\nTOY's intimate connection with their child audiences continues even after the final curtain. As a part of the end of every performance, they convene a \"talk back\" session moderated by Quinn that prompts young attendees with questions intended to stir up their natural curiosities to think, respond and reflect on the onstage narrative they just watched.\n\"As we prepare for plays, I always tell the actors to give this next performance your best, because you could be introducing people to something new,\" said Quinn. \"Some children have never seen a play before, so these actors have the chance to create something memorable in their lives and make them feel like they belong.\"\nQuinn notes that this dialogue can plant the seeds for lives full of critical thinking and creative problem solving. According to her, children may exhibit greater confidence than grown-ups to ask profound questions; they are also challenged to think about making thoughtful choices in serious situations. To illustrate this, Quinn talked about a past performance, Tuck Everlasting, where the main character must choose between drinking magic water to live forever – thus outliving close friends and loved ones – or abstaining and live a natural life. Theatre of Youth exists not only to enrich, educate and entertain young audiences, but also to challenge children to reflect on the greater themes of life.\n\"Kids constantly ask questions about their place in life and whether [they will succeed],\" she said. \"We embrace their desire to explore and get to the essence of the story. And we provide a forum for it. If you know how to explore it that way, then you've got them. That's a really powerful thing.\"\nTo learn more about Meg and Theatre of Youth, visit http://www.theatreofyouth.org.", "pred_label": "__label__POS", "pred_score_pos": 0.6874383687973022}
{"content": "Every practising solicitor must have professional indemnity insurance (PI), which protects against negligence claims made by clients. Like your law firm, solicitor's professional indemnity insurance policies are unique and it’s crucial that you select the right one to ensure your business is appropriately covered.\nUnsure where to begin? That’s where this guide to solicitors PI will help. In it we explain what solicitor’s professional indemnity covers, how to optimise your proposal form, how the renewal process works and what to do if a claim is made against your law firm. We're here to help\nIf you have any questions or would just like to speak to one of our specialists, then you can email us directly.\nData processing - FAQs What will you do with my data?\nWe will always keep your personal information safe and only ask for it to send you relevant insights and product information which may be useful to you and your business. We will not pass your information to any third parties and you can unsubscribe at any time.\nWhat if I don't want to opt-in to receive your insights?\nThat's fine, you don't have to opt-in. We just need you to agree to our privacy notice, which you can read here.\nIf I opt-in, how often will you send me communications?\nWe won't bombard you and will only send you market updates and content that is relevant to you. We usually send one to two emails per month.", "pred_label": "__label__POS", "pred_score_pos": 0.5969369411468506}
{"content": "The European Labour Market Barometer rose again in October. The leading indicator for the European labour market generated by the European Network of Public Employment Services and the Institute for Employment Research (IAB) rose by 0.5 points. Reaching 99.2 points the indicator is still in the negatives but has now recovered a significant part of the sharp decline in April.\nThe labour market in Europe has recovered after the first lockdown in spring. However, the second Corona wave poses a major risk throughout Europe once again,\nexplains the IAB research department head Enzo Weber, who initiated the European Barometer.\nIt should be noted that the survey period ended before the strong increase in infections in the past two to three weeks. The sub-indicator of the European Labour Market Barometer for the development of seasonally adjusted unemployment rose by 0.8 to 100.3 points in October. It has thus left the negative area that signals rising unemployment in the next three months. The sub-indicator for employment also increased compared to the previous month. At a value of 98.2, it continues to reflect scepticism about the employment trends despite a plus of 0.3 points.\nThe uncertainty about further setbacks on the European labour market remains\nsays Weber.\nThe European Labour Market Barometer is a monthly leading indicator based on a survey among the local or regional employment agencies in 15 participating public employment services. The survey has been carried out jointly by the employment services and the IAB since June 2018. Participating countries include Austria, Bulgaria, Cyprus, the Czech Republic, Denmark, Belgium-DG, Belgium-Flanders, Germany, Iceland, Liechtenstein, Lithuania, Luxembourg, Malta, Portugal and Belgium-Wallonia.\nWhile component A of the barometer signals the development of the seasonally adjusted unemployment figures for the next three months, component B forecasts employment trends. The average of the components “unemployment” and “employment” constitutes the total value of the barometer. This indicator thus provides an outlook on the overall development of the labour market. The scale ranges from 90 (very poor development) to 110 (very good development). For each of the participating employment services, a barometer is determined, from which the European barometer is derived as a weighted average.\nThe time series of the European Labour Market Barometer including its components for all 15 participating employment services are available at www.iab.de/Presse/elmb-components.\nSie würden gerne Auszüge oder die gesamte Presseinformation in Ihr Redaktionssystem übernehmen?\nSie finden sie unter\nwww.iab.de/presse/elmb1020.\nMore information on the European Labour Market Barometer is available at https://www.iab-forum.de/en/launch-of-the-european-labour-market-barometer/.", "pred_label": "__label__POS", "pred_score_pos": 0.7257605791091919}
{"content": "New Reporting Process Allows Easier Return to Disability Assistance After Exceeding AEE Limit On September 1st the Ministry of Social Development and Social Innovation (MSDSI) will introduce a new procedure which will make it easier for people receiving disability assistance who exceed their Annual Earnings Exemption (AEE) limit to return to assistance. Recipients who wish to do so can continue to submit a monthly report slip to MSDSI even after they reach their AEE limit and cease to be eligible for assistance. Once the AEE limit is renewed the following January or if a person's earned income falls below their disability assistance rate during the year then disability assistance can be automatically re-instated. Monthly reports are due by the 5th day of the following month that income is received (e.g. income received in May should be reported by June 5th). Monthly reports can be completed online using My Self Serve or submitted to a Ministry office using the Monthly Report form (HR0081). People who choose not to report income on a monthly basis after they exceed the AEE limit keep their disability designation and will not need to reapply for the designation using the 28 page PWD designation application. However, they will need to submit a re-application for assistance which assesses financial eligibility if they wish to return to disability assistance.\nAnnual Earnings Exemption Refresher\nThe AEE allows people on disability assistance to receive earned income (usually this means income received in exchange for work or the provision of a service) without a reduction to their disability assistance. A person's AEE limit is the amount of earned income they can receive during the year without a reduction of disability assistance. Any earned income received after a person exceeds their AEE limit is deducted dollar for dollar from their disability assistance. The maximum AEE limit for a single person is $9600 per year (pro-rated for the number of months a person is receiving disability assistance in the year).\nThe AEE limit is renewed every January which, due to the MSDSI reporting system, allows people who are otherwise eligible for disability assistance to begin receiving assistance again in February for the March benefit month. The AEE does not apply to other sources of income (e.g. Canada Pension Plan Disability Benefits, Employment Insurance, Old Age Security), which are generally deducted dollar for dollar from disability assistance unless there is a specific exemption.\nIf you have any questions about this information, please contact Advocacy Access Program Director Sam Turcott at 604-872-1278 or 1-800-663-1278.", "pred_label": "__label__POS", "pred_score_pos": 0.6414066553115845}
{"content": "Renter’s insurance is an often overlooked policy. Insured’s are aware of the need for home insurance if they own a property. However, they fail to realize the importance of protecting their possessions and personal liability when renting an apartment or home in Massachusetts.\nMA apartment insurance is extremely affordable, with many insured’s getting the coverage nearly free when combining it with an auto insurance policy. We highly recommend taking advantage of this coverage to protect your clothes, furniture, electronics and personal liability in the event of a fire, theft, vandalism or other covered perils. Please remember to keep track of your possessions as well. This is critical in the event of a claim.\nAn associate at Zawada Insurance would be happy to walk you through the details of your renter’s policy to explain your coverage options. Contact Zawada Insurance today for comprehensive coverage at a competitive price at (508) 831-0133.", "pred_label": "__label__POS", "pred_score_pos": 0.5285642147064209}
{"content": "Connecting Standards, Instructional Materials, and Professional Learning for Equitable Outcomes\nTeachers deserve high-quality instructional materials and ongoing support to implement those materials. Mounting evidence suggests that providing teachers with access to high-quality, standards-aligned instructional materials and curriculum-based professional learning can result in improvement in student outcomes, making this a research-based continuous improvement strategy. Learn more about this research here.\nThe Wisconsin Department of Public Instruction aims to improve support for all teachers by ensuring that districts have the information they need to select high-quality instructional materials and to provide professional learning that supports effective implementation of those materials in English language arts and mathematics.\nEquity for Teachers, Equity for Students\nSelect rigorous academic standards.\nSelect high-quality, aligned instructional materials.\nProvide ongoing professional learning opportunities on the selected materials. Are Your Instructional Materials Aligned?\nAs a local control state, districts and schools in Wisconsin make important decisions regarding instructional materials. There are growing efforts to support this decision-making process. EdReports is one tool to determine whether instructional materials are aligned to Wisconsin’s academic standards in English Language Arts and Mathematics. View their rubrics and ratings of specific curricula. If your instructional materials are not included on EdReports, see the Instructional Materials Evaluation Tool from Achieve as another tool to use.", "pred_label": "__label__POS", "pred_score_pos": 0.9586821794509888}
{"content": "Abstract\nThis article studies whether the Purchasing Managers’ Index (PMI) can lend itself usefully to the forecasting of future stock returns. Utilizing time-series regression analyses, we find a positive relationship between changes in PMI and stock returns. This suggests that optimism (pessimism) as indicated by changes in the PMI translate into higher (lower) subsequent stock returns. Additionally, after controlling for macroeconomic conditions such as the strength of the U.S. dollar, inflation, and the current state of the U.S. economy, these results persist. The results show PMI changes have a greater impact on the stocks of smaller market capitalization firms and industries such as precious metals, computer technology, textiles, and automobiles. The article examines how PMI’s forecasting role has evolved over time using rolling regressions and including changes in PMI as an additional factor in Fama and French’s popular three-factor model.\n© 2011 Pageant Media Ltd", "pred_label": "__label__POS", "pred_score_pos": 0.8199384808540344}
{"content": "CK Kumaravel\nCK Kumaravel, Co-founder and CEO, Naturals Salon, shares his investment preferences\nKripa Mahalingam - November 13, 2019\nSahil Gilani\nSahil Gilani, Director-Sales and Marketing, Gits Food, shares his investment preferences\nKrishna Gopalan - November 13, 2019\nWhere The Rich Are Investing\nOutside of their own business, equities and start-ups have emerged as the primary financial assets of the rich and the famous. Structured debt is no longer in vogue\nKripa Mahalingam - November 25, 2019\nFear factor\n20/20 denotes perfect visual acuity but, as we head into the leap year, the outlook appears hazy and bleak\nN Mahalakshmi - November 05, 2019\nWhere the rich are investing\nDespite volatility, equity and debt are still the darlings of the ultra rich, but the flavour of the season is clearly alternative investments\nKrishna Gopalan - November 14, 2018\nPotent Cocktail\nWith uncertainty at its peak, 2019 promises to be an edge-of-the-seat thriller\nN Mahalakshmi - November 09, 2018\nWhere The Rich Are Investing\nHere’s how India’s ultra rich are redeploying their wealth amid falling return from two prominent asset classes — real estate and fixed income\nV Keshavdev - November 07, 2017\nWhere the rich are investing\nHere's a look at how India's ultra rich are deploying their wealth\nKripa Mahalingam - November 17, 2015\nWhere the rich are investing\nHow India’s affluent families are creating and growing their personal wealth\nKrishna Gopalan - August 03, 2015\nThe midas touch\nOur idea of tracking where the rich are investing — and the advice they are getting from their managers — is to simply get a sense of the investment climate\nN Mahalakshmi - February 19, 2016", "pred_label": "__label__POS", "pred_score_pos": 0.797597348690033}
{"content": "Floyd Medical Center has been named a Georgia Safe to Sleep Hospital by the Georgia Department of Public Health, highlighting the hospital's continued commitment to infant safety.\nGeorgia has one of the highest infant mortality rates in the country. Every week, three infants in Georgia die due to sleep-related causes, many of which are preventable.\n\"By utilizing safe sleep practices, we have an incredible opportunity to help new parents learn how to protect and care for their baby when they return home,\" explained Director of the Family Birth Center Kellie Pearson. \"It's been shown that observing hospital staff utilizing these safe techniques reinforces the same behavior in the parents.\"\nIn 2016, Floyd signed a pledge of intent to participate in the Georgia Department of Public Health's Safe to Sleep initiative.\n\"What's most troubling about statewide statistics related to infant mortality is that so many of these tragedies could have been prevented with proper education,\" Pearson added. \"At Floyd, we are committed to becoming a leader in the effort to protect infants and reduce the number of preventable deaths.\"\nThe Safe to Sleep designation indicates that Floyd staff have educated co-workers and parents, implemented a safe infant sleep policy, modeled safe sleep while babies are in the hospital and distributed educational support materials. It also signifies Floyd has completed a crib audit to measure compliance with safe sleep recommendations:\nAlone - Babies should sleep alone in their own space, close to, but separate from their caregiver.\nBack - Babies should be placed on their back every time they go to sleep.\nCrib - Babies should sleep in a crib or bassinet with a firm, flat surface with no extra things such as crib bumpers, blankets or toys.", "pred_label": "__label__POS", "pred_score_pos": 0.5605579614639282}
{"content": "“Vision, Passion, and Care:” The Impact of Charismatic Executive Leadership Communication on Employee Trust and Support for Organizational Change\nChange, particularly organizational change, can be difficult for many people. By supporting change through positive leadership communication practices, employees are more apt to be open to supporting that change. This brings with it a wealth of potential for positive and productive business practices.\nDespite the crucial role of executive leadership communication during change, knowledge on how to conduct such leadership communication is lacking. University of Florida College of Journalism and Communications Public Relations Associate Professor Rita Men, with doctoral student April Yue and Dr. Yonghong Liu from the University of North Carolina, wanted to explore how charismatic executive leadership communication could nurture employee trust, thus positively affect employee reactions to change.\nCharismatic executive leadership communication is defined by three behavioral dimensions: envisioning (communication about vision), energizing (communication about passion), and enabling (communication about care and support).\nThe study suggests that employee trust can lead to a positive reaction to change, an openness to change, and, perhaps most importantly, behavioral support for that change.\nResults showed that charismatic executive leadership communication, featured by executive leaders’ envisioning, energizing, and enabling change communication behaviors, largely contributed to employee’s positive reactions to change, both in terms of openness to change and in behavioral change. When leaders communicate a compelling vision for change, express excitement, passion, and confidence about change, and exhibit care, emotional support, and empathy surrounding change, this leads to behavioral support from employees.\nResults also demonstrate that trust in leadership is a key factor in how employees respond to change. Trust takes time and consistency to build, so a relationship-oriented, intentional communication strategy is necessary for ultimate positive results in leading a team or organization through any sort of institutional change.\nThe original research paper, “ ‘Vision, Passion, and Care:’ The Impact of Charismatic Executive Leadership Communication on Employee Trust and Support for Organizational Change ,” appeared in Public Relations Review , 17 May 2020. Authors: Linjuan Rita Men, University of Florida; Cen “April” Yue, University of Florida; Yonghong Liu, University of North Carolina, Greensboro. This summary was written by Marie Morganelli, Ph.D.", "pred_label": "__label__POS", "pred_score_pos": 0.907420814037323}
{"content": "South Korea's financial regulator said that it will open the country's first financial data exchange in March, a move that could boost the data-driven economy.\nThe exchange will serve as a key platform for buyers and sellers of financial, telecommunication and corporate data. It is meant to facilitate financial big data, according to the Financial Services Commission.\nThe move came nearly two weeks after South Korea's parliament passed three bills designed to ease regulations on the use of personal information, despite objections from privacy advocates.\nThe three bills related to data are intended to enable the use of personal information offered under an alias and processed technologically to conceal the provider's identity, without the user's consent, for compiling statistics and industrial research purposes.\nIn 2018, President Moon Jae-in stated that \"data economy\" is a key to South Korea's innovative growth. He expressed his determination to improve the legal system so that South Korea can emerge as a global powerhouse in data use, beyond just being an internet-savvy nation.", "pred_label": "__label__POS", "pred_score_pos": 0.9247402548789978}
{"content": "Stakeholders in Egypt’s entrepreneurship ecosystem are now offering numerous opportunities and support mechanisms for local start-ups grappling with slowing markets due to the ongoing coronavirus (COVID-19) pandemic.\nFrom financing to business and psychological support, the stakeholders are using an array of online tools and functions to push the entrepreneurial ecosystem forward.\nFalak Startups pumps new investments\nThe Falak Startups accelerator is offering up to EGP 1m in direct investment and support for start-ups in the healthtech, insuretech, fintech, logistics, 3D printing, remote work solutions, and e-learning fields. The investment is to enable growth in these sectors and strengthen their chances to thrive\n. This opportunity falls outside of their cycle process due to the strong need for certain services due to the coronavirus outbreak. Falak’s mission is to invest and nurture the next generation of entrepreneurs by providing them with the proper funding and tools to positively contribute to the economy. AUC Venture Lab launches online activities\nAmerican University in Cairo (AUC)-based incubator, Venture Lab (V-Lab), has launched three online activities to support entrepreneurs. The V-Lab Quarantine Clinic offers entrepreneurs free 25-minute one-on-one online consultations and mentorship sessions. V-Lab has partnered with Takestep, Altibbi and RiseUp Connect for free psychiatric consultation sessions\nTechne Bytes fireside chat series\nTechne platform has been hosting several regional online fireside chats since the start of the COVID-19 outbreak. The series has now gone international with the “Techne Bytes” interview series, which takes place every Sunday and Tuesday. The series hosts world industry experts, such as Managing Partner at Middle East Venture Partners (MEVP) Walid Mansour, and Director of Consumer Marketing Commerce & Payments at Facebook Noha Rizk. The series is designed to help entrepreneurs take the next steps in their journey despite the tough times. Techne had also previously moved the final stages of “Techne Drifts” online, resulting in more virtual attendees. Techne Drifts is a series of events that take place across Egypt to empower and strengthen entrepreneurs nationwide. Techne is a platform for a group of initiatives that support tech and tech-enabled start-ups around the Mediterranean region.\nSeedspace Cairo creates virtual hackathon\nSeedspace Cairo launched its virtual hackathon, SeekNotHide, in partnership with Startup Haus Cairo, Gemini Enterprises Africa, Ibtikar Khana, Ashoka, and Wuzzuf. The hackathon was a platform on which to combat the challenges that entrepreneurs and start-ups are facing due to the COVID-19 outbreak. Seedspace is a learning and working environment empowering tech entrepreneurs to tackle the complex challenges our world is facing.\nEndeavor provides resources for entrepreneurs\nEndeavor, a global non-profit organisation that supports high-impact entrepreneurs, has created an open-source library of curated, vetted crisis management resources. The library is designed to help entrepreneurs measure, plan and execute their plans during these unprecedented timee. Resources include articles, expert advice and webinar recordings around topics such as remote working, business continuity, contingency planning, and more. Operating across 37 markets, Endeavor is leading the global high-impact entrepreneurship movement to drive long-term economic growth. It also looks to build strong entrepreneurship ecosystems by selecting, mentoring, and accelerating the most impactful entrepreneurs.\nRainmaking Innovation launches “AMPLIFY” initiative\nThe Egypt-chapter of global innovation studio, Rainmaking Innovation, has called on entrepreneurs and founders of growth-stage start-ups to join its own AMPLIFY initiative. Aimed at creating commercially viable partnerships between start-ups and corporates in the banking sector, the initiative looks to ramp up B2B engagement proposals, whilst offering itself as an innovation partner. Through this, it looks to enable start-ups to harness the opportunity to ramp up their competitiveness despite the impact of the coronavirus. The initiative explores B2B commercialisation, piloting and corporate traction opportunities. Rainmaking Innovation is the mother company of global industry-focused accelerator Startupbootcamp. Globally, Rainmaking has facilitated over 300 corporate-start-up pilots, with over 200 corporate partners, at an 86% success rate. The deadline for applying to the initiative is 20 April.", "pred_label": "__label__POS", "pred_score_pos": 0.8046674728393555}
{"content": "by David Aurelio.\nAs the S&P 500’s 19Q1 earnings season enters the final stretch, Broadcom Inc (AVGO.OQ) delivered a heavy blow to the Semiconductors and Semiconductor Equipment industry when they reported revenue below expectations and provided a cautionary warning related to U.S. China trade and OEM inventory levels.\nNearly all of the S&P 500 companies (496) have reported 19Q1 earnings and roughly three quarters (75.6%) have beat expectations. As a result, first quarter earnings are now expected to increase 1.6%. This is an improvement from the expected two percent decline and earnings recession that was expected at the beginning of the of earnings season back on Apr. 1, 2019. However, just as investors may have warmed up to the idea that an earnings recession isn’t expected, a report from semiconductor giant Broadcom has caused many to take note.\nBroadcom’s conference call is significant due to the change in their outlook for a recovery in the second half, emphasis on the potential impact of the U.S.- China trade conflict, and highlights of OEMs risk reduction through decreased inventory.\nDuring the earnings call, Hock E. Tan, Broadcom Inc. – CEO, President & Executive Director, said, “Let me address the current business environment and our outlook for the remainder of the year. We have, as I indicated, performed very much to plan in the first half of fiscal ’19. And in the second half, we had expected a recovery. However, while enterprise and mainframe software demand remained stable, particularly in North America and Europe, with respect to semiconductors, it is clear that the U.S.- China trade conflict, including the Huawei export ban, is creating economic and political uncertainty and reducing visibility for our global OEM customers. As a result, demand volatility has increased and our customers are actively reducing inventory levels to manage risks. This leads us to believe the second half of 2019 will be more in line with the first half as opposed to the previously expected recovery. We now anticipate fiscal 2019 semiconductor solutions segment revenue of $17.5 billion, which translates into a year-over-year decline in the high single digits.”\nExhibit 1: S&P 500 Inventory to Total Assets Ratios by Sub-Industry\nInventory to total assets for the technology hardware, storage & peripherals sub-industry is expected to decline to 3.7% in 19Q2 from 3.9% in 18Q2. Apple Inc (AAPL.OQ) is expected to see inventory to assets of 1.4% in 19Q2 vs. 1.7% in 18Q2 and HP Inc (HPQ.N) is expected to be 16.7% in 19Q2 vs. 17.8% in the prior year. Therefore, it appears that analysts are also expecting many OEMs will reduce risk through inventory management.", "pred_label": "__label__POS", "pred_score_pos": 0.905586302280426}
{"content": "Many people are unaware of the time, expense, and frustration of end-of-life obligations. Many people are also unaware that obstacles can be easily avoided with proper estate planning. If you do not have a will, the courts must distribute your assets upon death in the manner outlined under statute. Many times, surviving family members receive items in a decedent’s estate that were not meant for them. In the worst cases, an improperly drafted will can be voided all together, resulting in the wishes of the decedent not being carried out.\nLaws of Intestacy Intestacy or intestate means passing away without a will. As a very general description, in Pennsylvania, if there is no valid will, a person's property is distributed in the following manner: 1. Spouse, 2. Any children, 3. Siblings, 4. Nieces and Nephews, 5. Grandparents, 6. Uncles and Aunts, 7. First and Second Cousins, and then, 8. the Commonwealth of Pennsylvania.\nIf this is not how you want your property distributed, you need a will. A will circumvents the default passing of property under the statutes and can be modified or revoked at any time. We can prepare for what will happen when your estate is distributed upon death. There are many considerations such as to where bank accounts, life insurance proceeds, vehicles, property (both real and personal), child custody, and sentimental items will default. We can create an effective plan that will ensure your wishes are honored without dispute, so that your family and property is protected in the unfortunate events of death or incapacitation. We can create the following tools within your estate plan to memorialize your wishes:\nWills\nLiving wills\nPowers of attorney\nHealthcare directives\nTrusts containing either money or property\nPay-on-death accounts\nSchedule a free consultation\nYou can call (412) 448-2326 or complete the form below. There is no obligation to retain our services, but we need to properly assess your case. We will respond to your inquiry within 24 business hours.\n*Notice: Usage of this website or contact form does not automatically create an attorney-client relationship.", "pred_label": "__label__POS", "pred_score_pos": 0.8232783079147339}
{"content": "Biogen and Eisai have decided to scrap the Phase III ENGAGE and EMERGE clinical trials evaluating aducanumab for the treatment of mild cognitive impairment due to Alzheimer’s disease, and mild Alzheimer’s dementia.\nThe move comes after a futility analysis by an independent data monitoring committee revealed that the trials were not likely to meet their primary endpoint upon completion.\nBiogen and Eisai noted that the decision is not based on safety concerns with the drug.\nReuters reported that the decision to discontinue the trials wiped out more than $18bn from Biogen’s market value, with the company's shares dropping approximately 30% to $225.70.\nAducanumab is an investigational, human monoclonal antibody (mAb) licensed by Biogen from Neurimmune. Biogen partnered with Eisai in October 2017 to develop the drug candidate globally.\nThe therapeutic is derived from B cells extracted from healthy elderly individuals with no signs of cognitive impairment or cognitively impaired elderly subjects having unusually slow cognitive decline.\nClinical trials ENGAGE and EMERGE were intended to assess the efficacy and safety of aducanumab in treating early Alzheimer’s.\nThe primary objective of the multi-centre, randomised, double-blind, placebo-controlled, parallel-group trials was the efficacy of monthly doses in slowing cognitive and functional impairment, compared to placebo.\nBiogen CEO Michel Vounatsos said: “This disappointing news confirms the complexity of treating Alzheimer’s disease and the need to further advance knowledge in neuroscience.\n“Driven by our steadfast commitment to patients and our strong business foundation, we will continue advancing our pipeline of potential therapies in Alzheimer’s disease and innovative medicines for patients suffering from diseases of high unmet need.”\nThe partners additionally noted that the Phase II EVOLVE safety study and the long-term extension of the Phase Ib PRIME trial of aducanumab will also be halted.\nData from the ENGAGE and EMERGE trials will be further assessed, and the initiation of a Phase III secondary prevention trial will also be evaluated.\nMeanwhile, Eisai has announced the launch of a Phase III Clarity AD trial of BAN2401 in patients with early Alzheimer’s. BAN2401 is an anti-amyloid beta protofibril antibody being co-developed by Eisai and Biogen.\nThe Clarity AD trial is designed to include 1,566 subjects with mild cognitive impairment (MCI) due to Alzheimer's disease (AD) or mild Alzheimer's disease dementia.", "pred_label": "__label__POS", "pred_score_pos": 0.7922252416610718}
{"content": "Abstract:\nAlzheimers disease (AD) is a progressive neurodegenerative disease characterized by cognitive decline associated with a deficit in cholinergic function. Inhibitors of acetylcholinesterase (AChE) and/or butyrylcholinesterase (BuChE), such as donepezil, galantamine or rivastigmine, are widely prescribed as symptomatic treatments for AD. These agents exhibit a wide variation in their pharmacological properties. Here we review clinical data from 1998 to 2009 investigating the effects of different cholinesterase inhibitor treatments on the levels and activities of cholinesterases in the cerebrospinal fluid (CSF) of AD patients. These studies suggest that treatment with rapidly-reversible cholinesterase inhibitors (e.g. donepezil, galantamine, tacrine) is associated with marked and significant upregulation of AChE activities and protein levels in the CSF of AD patients. In contrast, pseudo-irreversible cholinesterase inhibition (e.g. rivastigmine) is associated with a significant decrease in both CSF AChE and BuChE activities, with no upregulation of CSF protein levels. Additionally, donepezil is associated with a decrease in the level of the AChE-R isoform relative to the synaptic AChE-S isoform, whereas rivastigmine seems to increase this ratio. These findings suggest that these agents exert different effects on CSF cholinesterases. The clinical effects of these pharmacological differences are yet to be fully established.\npromotion: free to download\nKeywords: Cholinesterase inhibitors, Alzheimer's disease, cerebrospinal fluid, acetylcholinesterase, butyrylcholinesterase\nRights & PermissionsPrintExport Cite as", "pred_label": "__label__POS", "pred_score_pos": 0.6267692446708679}
{"content": "Economic leterature has stressed the importance of collaboration among accademia, industry and government as a key driver of innovation. This paper analyses the effects of public funding in promoting cooperation in innovation activities in Italy and in Germany, using data from the sixth Community Innovation Survey. The results show that in both countries receiving public support is positively related to undertaking collaborative innovation, but in Germany this relationship is the strongest. In Italy it varies depending on the funding source, whereas regional incentives on promoting collaboration are weak. This result is largely related to the size of the firm benefiting from this type of pubblic support (small and medium-sized firms) and from the industrial sector theyb belong to (low-technological industries). Additionally, the data show that public financial support also influences the choice of partners, making it easier for firms to adopt a more complex rqange of linkages, including suppliers, clients, and reaserch institutions. Keywords: Innovation policy, Cooperation, Public funding: Behavioural additionality, Community Innovation Survey Jel Code: O31; O32", "pred_label": "__label__POS", "pred_score_pos": 0.6803221106529236}
{"content": "The death of a family member in Pennsylvania or anywhere else involves grief for the survivors. However, as the executor of the decedent’s estate, you are responsible for many administrative details. Larger estates with complex assets can impose significant paperwork burdens on an executor. You will need to navigate many details surrounding the payment of debts, tax filings and asset transfers.\nChoosing a probate court\nA will needs to be filed with a probate court. Typically, you file the will with the probate court within the county where the person lived at the time of death. Someone who died while living out of state or in a different county than where the decedent’s real estate was located might need the will filed in the county where the real estate is.\nInforming creditors\nAn estate must pay off its debts, including credit card bills, home loans and personal loans. You will need to determine the value of an estate’s assets so that you know what funds are available to pay debts. This step alone could be time consuming as you try to track down assets and get them appraised. You will also place a Notice to Creditors in a local news publication to give creditors a chance to make a claim against the estate during probate.\nFiling taxes\nYou will need to complete an income tax return for the last year that the person was alive. Very large estates may also have estate tax obligations that must be paid on time.\nNotifying and paying heirs\nAs the executor, you will inform beneficiaries that they were named in the will. Transferring real estate to heirs or selling it first will take up more of your time than simple cash transfers.\nStaying organized\nWhile closing out an estate, you could encounter some surprises. Following the law is important for avoiding disputes and ensuring that all creditors and heirs receive their payments. You may want to learn more about how legal advice and estate administration services might reduce your workload and prevent costly delays.", "pred_label": "__label__POS", "pred_score_pos": 0.5198030471801758}
{"content": "£3.9 million modern languages research project launched in Manchester\nA consortium led by The University of Manchester has launched a four-year language research project which aims to demonstrate the UK’s critical need for modern languages research and teaching. The project will collaborate with schools and universities to develop curriculum innovations, and strengthen university commitments to local community heritage.\nThe launch of ‘Cross-Language Dynamics: Reshaping Community’, which is funded by an AHRC Open World Research Initiative (OWRI) grant, took place at The University of Manchester. They are leading a consortium which includes 11 other universities, city councils, the Royal Opera House, Tyneside Cinema, political think tank Chatham House, and a sixth-form college known for its strengths in modern languages. The event featured presentations by the project researchers and performances of film, dance, music and song by artists and members of local communities. Working across several world languages, among them Arabic, Spanish, and Russian, the project will incorporate perspectives from Linguistics, Literary, Media and Cultural Studies, International Relations, the Arts (Music, Film and Theatre) and Visual Anthropology. It will feature three areas of research, each of which explore a particular kind of language community - Multilingual Communities (urban populations whose identity is shaped by language diversity), Transnational Communities (sharing a single language but dispersed across different nation states) and Translingual Communities (those formed through cultural creativity across language boundaries).\nWe hope that our research will demonstrate the critical importance of modern languages to all those who wish to gain a better understanding of our world, which is both more networked and more fragmented than ever.\nProfessor Yaron Matras, Professor of Linguistics at The University of Manchester and founder of the Multilingual Manchester initiative, will lead the project's Multilingual Communities strand. He added: “Universities need to re-think their approach to delivering language degrees, and anchor their work more tightly in local communities, their language diversity, and the need for global outreach.”", "pred_label": "__label__POS", "pred_score_pos": 0.952549934387207}
{"content": "Inflammatory and microenvironmental factors produced by cancer cells are thought to directly or indirectly promote cancer cell growth. Prostaglandins, including prostaglandin E2, have key roles as a microenvironment factor in influencing the development of tumors, and are produced by the rate limiting enzyme cyclooxygenase 2 (COX-2). In this study, we used canine melanoma cells treated with the proinflammatory cytokine interleukin 1β (IL-1β) and investigated the transcriptional factor nuclear factor-κB (NF-κB) signaling in IL-1β-induced COX-2 expression. IL-1β induced prostaglandin E2 release and COX-2 mRNA expression in a time- and dose-dependent manner. In the cells treated with the NF-κB inhibitors BAY11-7082 and TPC-1, IL-1β-mediated prostaglandin E2 release and COX-2 mRNA expression were inhibited. IL-1β also provoked phosphorylation of p65/RelA and p105/NF-κB1, which are members of the NF-κB families. The IL-1β-induced phosphorylation of p65 and p105 was attenuated in the presence of both NF-κB inhibitors. In melanoma cells transfected with siRNA of p65 or p105, IL-1β-mediated COX-2 mRNA expression was inhibited. These findings suggest that canonical activation of NF-κB signaling plays a crucial role for inflammatory states in melanoma cells.", "pred_label": "__label__POS", "pred_score_pos": 0.8157191276550293}
{"content": "Cyclical variations in liquidity risk of corporate bonds by Cassandre Anténor-Habazac, Georges Dionn\nAuthors study regime switching features of liquidity risk in corporate bond premiums. Within a sample period ranging from July 2002 to April 2015, they first compute a liquidity risk index for BBB bonds, which considers various liquidity risk facets based on principal component analysis. Second, they identify two liquidity regimes in our sample using a Markov switching regime model that highlights the dynamic characteristics of this risk and its behavior before, during and after the last financial crisis. They observe that the liquidity risk index improved after the financial crisis. It seems that the recent Volcker Rule did not affect the liquidity of BBB bonds during our sample period.", "pred_label": "__label__POS", "pred_score_pos": 0.8684216141700745}
{"content": "You should always clean water-damaged basements right away to stop mold. However, if you didn't clean the water right away, and you find mold, you can clean it yourself.\nConcrete walls are commonly mold-resistant, but concrete is still porous, and the right elements could cause the mold. Here are tips to clean mold from basement walls.\nPrepare to Work\nFor this project, you need:\nwork gloves safety glasses breathing equipment bucket sponge paper towels hard-bristled brush dish soap or trisodium phosphate (TSP) borax vinegar sump pump\nDon't breathe mold spores. Always wear breathing equipment.\nLearn the signs of mold. Before you check for mold, shut off the power before you enter a flooded basement to prevent electrocution.\nThe first sign of mold is a musty smell. The smell of mold is distinctive, and it can't be remedied with a deodorizer. Allergic reactions such as headaches or wheezing could indicate a mold problem. Mold is commonly black, pink, white, or orange splotches.\nDry the Water\nDry out as much water as possible. Open windows, and use a sump pump to remove standing water. Sump pumps can be rented from home improvement stores. Trace and fix the source that caused the damage.\nIf there's a sump pump already installed, it should activate when the pit fills with water. Salvage what items you can, and disinfect them with vinegar.\nMix some vinegar and warm water in a spray bottle, spray it on the object. Clean the surface with a sponge. Items with severe mold growth should be discarded.\nClean the Mold\nPre-treat the mold by cleaning the walls with a sponge and mild dish soap. TSP is a powerful degreasing agent, but handle it with caution. Keep it away from glass, since it will etch the glaze. Mix a half a cup of TSP in a gallon of warm water.\nBorax is a safer alternative than bleach. Bleach is commonly suggested for mold removal, but it is only good for non-porous surfaces, as it doesn't go deep. Borax doesn't produce the toxic fumes like bleach does.\nCombine a cup of borax in a gallon of warm water. Scrub the area thoroughly with a hard-bristled brush. Wash off the solution with paper towels; inspecting the walls for any mold you may have missed.\nAfter the mold has been removed, disinfect the area with vinegar. Mix vinegar with some water, and spray down the walls, and let it dry.\nTo prevent mold problems in the future, lower the humidity with a dehumidifier, and keep watch for leaks. If you don't trust your skills, or the basement still hasn't dried, or mold returns, contact a water restoration service such as Complete Restoration Services.\nShare", "pred_label": "__label__POS", "pred_score_pos": 0.8473913669586182}
{"content": "While colonial imposition of the Canadian legal order has undermined Indigenous law, creating gaps and sometimes distortions, Indigenous peoples have taken up the challenge of rebuilding their laws, governance, and economies. Indigenous conceptions of land and property are central to this project.\nCreating Indigenous Property identifies how contemporary Indigenous conceptions of property are rooted in and informed by their societally specific norms, meanings, and ethics. Through detailed analysis, the authors illustrate that unexamined and unresolved contradictions between the historic and the present have created powerful competing versions of Indigenous law, legal authorities, and practices that reverberate through Indigenous communities. They have identified the contradictions and conflicts within Indigenous communities about relationships to land and non-human life forms, about responsibilities to one another, about environmental decisions, and about wealth distribution. Creating Indigenous Property contributes to identifying the way that Indigenous discourses, processes, and institutions can empower the use of Indigenous law.\nThe book explores different questions generated by these dynamics, including: Where is the public/private divide in Indigenous and Canadian law, and why should it matter? How do land and property shape local economies? Whose voices are heard in debates over property and why are certain voices missing? How does gender matter to the conceptualization of property and the Indigenous legal imagination? What is the role and promise of Indigenous law in negotiating new relationships between Indigenous peoples and Canada? In grappling with these questions, readers will join the authors in exploring the conditions under which Canadian and Indigenous legal orders can productively co-exist.", "pred_label": "__label__POS", "pred_score_pos": 0.8801080584526062}
{"content": "Article content\nMandatory public masking has been saving lives and leading to an earlier (and safer) reopening of societies around the world. Despite this, Canadian officials have been reticent to support this cheap, effective measure.\nAs of May 12, 13 U.S. states, including Illinois, New York and Massachusetts, and 84 countries, including Israel, Germany, Austria, Czechia and France, have laws mandating public masking. And zero Canadian jurisdictions.\ntap here to see other videos from our team.\nWe are emerging from a severe lockdown, taking tentative steps into the unknown. Over a period of seven weeks, Canadians have endured the challenges of physical isolation. The pressure to reopen society is immense, but many share our concern that reopening will cause a second wave of cases.\nAdvice for hand hygiene and physical distancing has been widely adopted and accepted.\nWhy not masks?\nCiting asymptomatic and presymptomatic spread, on April 6 Dr. Theresa Tam, Canada’s chief medical officer of health, stated “wearing a non-medical mask … is an additional measure that you can take to protect others around you in situations where physical distancing is difficult.”", "pred_label": "__label__POS", "pred_score_pos": 0.9926897287368774}
{"content": "Abstract\nRecords of 28 patients with pathologic lesions in the proximal femur treated by implantation of a femoral head and neck replacement prosthesis between 1984 and 1995 were reviewed. Mean clinical followup was 47.8 months in the eight living patients and 15.8 months in the 20 patients who had died. The underlying diagnosis was metastatic disease or myeloma in 22 patients. The most frequently occurring indication for implantation of this device was a pathologic fracture in 26 patients (18 displaced, eight impending), followed by resection and reconstruction in two patients. All femoral components were cemented: 23 were bipolar hemiarthroplasties and five were total hip arthroplasties. Implant survivorship was good (93%), with only two prostheses removed during the followup period, both for infection. However, radiographic analysis revealed increasing lucencies with time, particularly in the most proximal zones, resulting in radiographic failure in an additional case. Deep infection occurred in three cases, leading to resection arthroplasty in two patients. Periprosthetic fractures occurred in three cases, but only one occurred intraoperatively. Despite a high complication rate, the good implant survival during the shortened life span of these patients supports the continued use of femoral head and neck replacement prostheses in this population.\nASJC Scopus subject areas Surgery Orthopedics and Sports Medicine", "pred_label": "__label__POS", "pred_score_pos": 0.995689868927002}
{"content": "Tweet The following analysis of select counties of the Idaho real estate market is provided by Windermere Real Estate Chief Economist Matthew Gardner. We hope that this information may assist you with making better-informed real estate decisions. For further information about the housing market in your area, please don’t hesitate to contact your Windermere Powerhouse Group agent at 208-920-5966.\nECONOMIC OVERVIEW\nIt appears as if the significant COVID-19-induced contraction in employment Idaho experienced earlier this year is behind us (at least for now). Statewide employment declined modestly in March, but April was the real shock, with the loss of more than 78,000 jobs in the month, a decline of 10.2%. However, the economy appears to have turned around remarkably quickly, with a solid increase of 24,300 jobs in May. Idaho did see COVID-19 cases rise significantly in June, but the latest data appears to suggest that the trend has started to reverse. If this continues, I am hopeful more of the jobs lost will return.\nHOME SALES During the second quarter of 2020, 6,264 homes were sold, a drop of 10.6% when compared to the second quarter of 2019. However, I would note that sales rose 22.2% compared to the first quarter of this year. In the southern markets, sales rose in small Valley County, but dropped in the rest of the counties covered in this report compared to the same period a year ago. Year-over-year, sales growth was negative in all of the Northern Idaho counties contained in this report. The most substantial drop was in Bonner County, though the decline there amounted to only 37 units. Pending sales rose a significant 18% over the first quarter of the year, suggesting that closed sales will rise in the third quarter.\nFor More Information and local real estate market statistics and forecast for County, City and Neighborhood throughout Ada County.\nSend and email or call us at 208-920-5966.", "pred_label": "__label__POS", "pred_score_pos": 0.7509676218032837}
{"content": "Healthcare costs reach $9.9K per person, remain historically modest\nBy Admin | December 28, 2016\nThe passage of the Affordable Care Act allowed nearly 20 million Americans to obtain health care; prior to the act, they were unable to.\nHowever, rising health costs cannot be entirely blamed on this new group of people in the health insurance pool. Other factors contribute to the new average of per-person cost, which hovers close to $10,000.\nSome of those factors include:\nConsumer out-of-pocket spending, like copayments, deductibles and spending not covered by insurance, excluding premiums. Cost of prescription drugs, the increase in generic prescriptions, increase in cost of name-brand drugs Rise in cost of clinical and physician services And others.", "pred_label": "__label__POS", "pred_score_pos": 0.8820116519927979}
{"content": "The CLC is delighted that BuildUK and CECA yesterday announced the launch of the first phase of a new pre-qualification (PQ) system designed to reduce the complexities and inefficiencies that are costing the construction industry up to £1 billion a year. This announcement supports the commitment in the Construction Sector Deal to create a standardised PQ process across the public and private sectors which will generate cost savings for firms in the construction supply chain by ensuring that they only have to go through a single certification process, rather than several.\nThe CLC will work closely with BuildUK and CECA to ensure that this system is quickly and effectively implemented.", "pred_label": "__label__POS", "pred_score_pos": 0.875600278377533}
{"content": "As our country continues to face racial violence and inequities, organizations have stepped up their focus on transitioning from discussions to taking actionable steps toward achieving racial diversity, equity, justice and inclusion. To support these efforts, we have created a drawing together leaders from across government, nonprofit, philanthropy and commercial sectors to move the needle toward real change. We invite you to join us! “Center within the Center,” “Center within the Center,”\nCenter for Race, Equity, Justice and Inclusion\nSubstantial work is needed to ensure the nonprofit and philanthropy sectors are equipped to develop, implement and sustain a racial equity workplan that supports all nonprofits, especially those led by leaders of color. Investment in leadership development and individualized capacity building that can be scaled is critical for sustainability through current challenges and into the future.\nTo intensify our focus around race and equity, the Center is launching a large-scale initiative—the\nCenter for Race, Equity, Justice and Inclusion (REJI). This “Center within a Center” will consist of five pillars: Researchwill begin with gathering data to inform future programming, including a 12-month, race equity experiential learning series for board members and executive directors Cross Sector Collaborationwill include educating partners in the philanthropic, government and education communities about the issues being addressed by nonprofit organizations serving communities of color, and the specific challenges nonprofits led by leaders of color are facing. Advocacywill begin with outreach to and engagement of regulating bodies to strongly encourage policy and system changes regarding charitable organizations, diverse leadership and board compensation. Experiential Learningwill assist nonprofit organizations with the development of a racial equity work plan, including developing policies and procedures to create an anti-racist environment that enables all employees to thrive; and will share local historical and other learning journeys that are impacting race and trust relations, as well as hands-on service learning from nonprofit leaders on the ground. Capacity Buildingwill provide support to help strengthen nonprofit leaders’ ability to create an anti-racist environment, expand funding to underserved communities and leaders, assist nonprofits in attracting and retaining employees of color, and train all employees to understand the value of diversity, equity and the importance of inclusion in their organizations. Leadership Series informs, equips and inspires black professionals to take the lead\nAccording to a recent article published in Nonprofit Quarterly, 80 percent of nonprofits are led by white executives, and yet poverty rates among people of color are twice as high as whites and they typically compose a higher number of those supported by nonprofits.\nAs part of our efforts to transition from discussion to taking actionable steps, the Center recently initiated—and provided at no charge, an 8-part course:\nNonprofit Leadership Series for Black Professionals. Offered over the summer, the course provided invaluable information and tools to prepare and inspire participants to succeed as leaders in the nonprofit sector. Sessions included financial analysis, using tools such as PIE and STAR, personal development, inspiring a team, accountability, engaging with recruiters, lessons from leaders and guest speakers, group coaching sessions, and more.\nThe series was very well received and appreciated by sixty-six participants from a variety of organizations, including top executives, senior leaders, managers, a few service coordinators and even a board member.\nSpecial thanks to Rob Malone, Executive Director, The Arc Prince George’s County, for leading this effort.\nThe Center launched on July 15\n… with the first in a series of panel discussions with prominent change makers. Panel discussions will focus on the journeys of leaders of color, as well as key issues impacting organizations and communities. A cross sector group of over 100 leaders from our region joined us our inaugural convening:\nSpecial thanks to the participants on our first panel: Lisa Brown Alexander, President & CEO, Nonprofit HR Darryl Maxwell, Assistant Director (Nonprofit & Small Business), DC Bar Pro Bono Center Marcus Walton, President & CEO, Grantmakers for Effective Organizations Moderator: Glen O’Gilvie, CAE, CEO, Center for Nonprofit Advancement Central pool of resources To help you with your own efforts and keep you informed, we will maintain this pool of resources, posting information, tools and webinars as we learn of them.\nPrepared by the Center\nPassword:#aUw^P30\nThis September workshop provided a clearer sense of what a racial equity journey might look like for your organization, and how you can ready yourself, your team, and your stakeholders for this work.\nPrepared by the Aspen Institute\nThis glossary describes terms related to structural racism and terms used to promote racial equity analysis. It was created by the Aspen Institute Roundtable on Community Change, a group that worked with leading innovators to produce strong and reliable frameworks for successful and sustainable community change and development.\nPrepared by Equity in the Center, a Project of ProInspire\nThis in depth, well researched publication provides a comprehensive guide for engaging your organization in the transformational work of building a Race Equity Culture.\nPrepared by Neo Law Group\nWhile discussions regarding DEI are increasingly prevalent in the nonprofit sector, the next, more difficult, step forward is to turn the discussions into action. This article outlines steps we can take—as part of the nonprofit community dedicated to the benefit of the public—to effectuate our commitment to DEI.\nProvided by Neo Law Group\nIn the nonprofit sector, there is an evident racial leadership gap. This article talks about how organizations can address this issue of inadequate representation for minorities by incorporating DEI provisions into their governance documents.", "pred_label": "__label__POS", "pred_score_pos": 0.5256693363189697}
{"content": "Understanding Fear In Yourself\nWe all know the story of Batman, a fictional hero who defends truth and justice and lives in integrity. What is the reason for being Batman? He wants to face the fear of bats by turning his intense fear into a source of amazing power. Even the bravest people have the fear to overcome. Are you afraid of something real, like a spider or a height? Or maybe you are afraid of failure, change, or something more difficult to determine? Whatever makes you afraid, you must learn to recognize, confront, and acknowledge that fear so that nothing will hinder you in life. To help you control your fears, you can visit our website to get books from stan popovich.\nKnow when your fears become excessive. Fear is normal. You may feel scared when riding a bike for the first time or when starting a new job. However, if fear begins to take over your life and affect activity, that’s a problem. If the fear begins to burden, the difficulties it causes can intervene with your ability to move and you may endure severe nervousness or anxiety. Do these fears prevent your steps from achieving what you want in life? Here are some things to consider:\n– Fear causes intense anxiety or panic.\n– You acknowledge that fear is irrational. – You avoid a specific place or situation. – Avoiding fear causes difficulties and disruptions to your activities. – The fear lasted for 6 months or more.\nUnderstand the symptoms of fear. Fear is often a phobia, which includes situations, animals, blood, injections, and so on. When you are afraid, there is a psychological, mental, and emotional reaction, which includes:\n– Heart beating fast\n– Hard to breathe – Dizzy – Sweating – Feeling anxious and panicked overload – Want to run – Feeling isolated – Feeling as if to faint or die – Feeling helpless in the face of fear, even if you know it is not rational", "pred_label": "__label__POS", "pred_score_pos": 0.8588383197784424}
{"content": "PxEng Consulting Inc. understands buildings are never static. Our process is derived from the understanding that truly dynamic buildings must align our clients’ functional needs – today and beyond. As consultants, we serve as a comprehensive, single point of contact on behalf of the client to enhance overall performance through building systems integration, which in turn maximizes energy utilization.\nFundamental to this process is ensuring Building Operators and Occupants are empowered to effectively and efficiently maintain their buildings with quantifiable improvements for the Occupant. We look beyond the building’s infrastructure, to the opportunities that optimized buildings provide to human well-being while being in balance with the environment.\nWith extensive experience in large-scale, complex buildings and campus projects, SK has spent his career in the consulting field focused towards finding innovative high performance solutions for his clients.\nA passionate proponent of building systems performance and accountability, SK was a key member behind the development of the partnership between PxEng Consulting Inc. and Builtspace™ in developing our digital platform.\nSK’s future-forward solutions not only provide a highly automated, mobile and accessible alternative to traditional data compilation, analysis and tracking via the Cloud, they realize a more sustainable future by eliminating the need for paper and bulky records storage.", "pred_label": "__label__POS", "pred_score_pos": 0.9298378229141235}
{"content": "Researchers in the School of Geography are actively engaged in partnerships with diverse Indigenous groups to advance understanding and communication of their ambitions, experiences, knowledges and rights. This research highlights the continuous presence of Indigenous peoples and their occupation of, rights to, and relationships with their cultures and countries.\nIt explores the tensions between Indigenous and Eurocentric knowledges, values, and institutions of exchange, governance, and management of lands and seas, and seeks ways to enhance the recognition and practice of Indigenous autonomy. This research is important for social justice, and because it provides a powerful critique of modern society as well as inspiration and knowledge for addressing contemporary social and environmental challenges.\nOur research partners include Indigenous groups in Australia, The Pacific Islands, South America, and South and South-East Asia.", "pred_label": "__label__POS", "pred_score_pos": 0.9778938889503479}
{"content": "Millions of women across the country have access to free screening mammography, thanks to its inclusion as a required essential health benefit under the Affordable Care Act (ACA). However, if the results of that screening mammogram suggest the need for a follow-up diagnostic exam to determine if the woman has breast cancer, she may be faced with hundreds to thousands of dollars in out-of-pocket costs — all before she ever gets to treatment.\nA recent Susan G. Komen-commissioned study found the out-of-pocket costs for patients to be high, with frequent variation for diagnostic breast imaging while also identifying the inconsistency in cost and coverage as a recognized issue among both patients and health care professionals.\nIf women are unable to afford the costs associated with diagnostic imaging, many might delay or forego additional tests to rule out or confirm a breast cancer diagnosis. This is unacceptable. It's time to take action!", "pred_label": "__label__POS", "pred_score_pos": 0.9634970426559448}
{"content": "Impact of temperature and storage time on the migration of antimony from polyethylene terephthalate (PET) containers into bottled water in Qatar Date2017 MetadataShow full item record Abstract\nProsperity in Qatar and the consequent stresses on water resources resulted in a sustainable increase in the bottled drinking water market. Reports on health concerns and possible migration of chemicals from the plastic material into the water have driven the current investigation. This study aims to address the extent of antimony (Sb) leaching from polyethylene terephthalate (PET) water bottles subject to temperature variations (24–50 °C) due to Qatar’s hot climate and improper storage conditions. A representative basket including 66 different imported and locally produced water bottles was considered. The concentrations of Sb in bottled water ranged from 0.168 to 2.263 μg/L at 24 °C and from 0.240 to 6.110 μg/L at 50 °C. Antimony concentrations in PET bottles at 24 °C was significantly lower than those at 50 °C (p = 0.0142), indicating that the temperature was a principal factor affecting the release of Sb from the plastic into the water. Although the detected Sb amounts were below the guidelines endorsed by WHO and Qatar (standard 5 μg/L) at 24 °C, the concentration measured at 50 °C was higher than the recommended WHO values (6.11 μg/L).", "pred_label": "__label__POS", "pred_score_pos": 0.7750258445739746}
{"content": "Most employment is at-will, meaning the employer generally has the right to discharge an employee at any time for any reason or for no reason at all. However, a termination or other job action cannot violate protections against unlawful discrimination or retaliation.\nFederal laws prohibit employment actions based on an individual’s sex, religion, age, race, national origin, disability, pregnancy status or veteran status. If an employee claims that you fired them because they are part of one of these protected classes, you could face an employment discrimination investigation by the U.S. Equal Employment Opportunity Commission (EEOC) along with a wrongful termination lawsuit requesting monetary damages and other relief.\nBefore you decide to sever ties with an employee, it is smart to prepare yourself for the possibility that you could face these legal ramifications. Here are some proactive steps that can be taken:\nWrongful discharge claims are often proved by circumstantial evidence, so taking these steps can help you overcome the inference that the reason given for firing the employee was a pretext for unlawful discrimination or retaliation.\nThe experienced employment law attorneys at Hemmer DeFrank Wessels, PLLC stand prepared to answer your questions about legal and illegal employment termination. We also help companies create employee handbooks and disciplinary processes, and we draft employment contracts and separation agreements. To schedule a free initial consultation, call 859-344-1188 or contact us online. We represent businesses in Kentucky, and Ohio.", "pred_label": "__label__POS", "pred_score_pos": 0.6002428531646729}
{"content": "SCOTTISH manufactured export volumes fell by 0.4 per cent in the third quarter of 2015, and overseas sales of the key drinks sector, which includes Scotch whisky, were flat, official figures have shown.\nA 15.7 per cent tumble in exports by the metals and metal products sub-sector played a significant part in the overall fall in the Scottish manufacturing sector’s overseas exports during the three months to September.\nHowever, the Scottish Government figures show that food exports increased by 17.3 per cent quarter-on-quarter during the three months to September. This marked a continuation of the strong performance by Scotland’s food producers since 2013, achieved in the face of challenging economic conditions and pressures arising from sterling strength against the euro.\nExports of the engineering and allied industries rose by 2.4 per cent during the three months to September. This was driven by increases in mechanical engineering and electronics exports.", "pred_label": "__label__POS", "pred_score_pos": 0.9948914051055908}
{"content": "Prior to the Thanksgiving holiday, kindergarten students in Ms. Eileen Moloney’s class at Giblyn Elementary School experienced a hands-on STEAM lesson creating sun shelters for Play-Doh pumpkins.\nThe purpose of the interactive lesson was to demonstrate why pumpkins’ leaves protect them from the sun creating their orange color. This was part of a larger discovery lesson about the lifecycle of a pumpkin.\nUsing construction paper, Play-Doh, popsicle sticks, pipe cleaners, paper plates and more the students built their sun shelters and then tested them by shining a flashlight on the top of the structure to see if the light entered the shelter or if their pumpkin was shaded. If the pumpkins were exposed to the light students made improvements to their shelters and retested to ensure their pumpkins would be fully sheltered from the light.", "pred_label": "__label__POS", "pred_score_pos": 0.7800083160400391}
{"content": "(Natural News) A recent study published in the journal Nutrition Research evaluated daidzein, a natural isoflavone derived from soy, for its ability to promote bone growth. In particular, the scientists from the Logistics University of Chinese People’s Armed Police Force built on previous research on daidzein’s protective effects against osteoporosis. In particular, it was compared with estradiol, a synthetic… >View original article Author:", "pred_label": "__label__POS", "pred_score_pos": 0.5837427973747253}
{"content": "YEC Central Regional Event 2018\nOver the last couple of years, Youth Environment Council (YEC) members expressed interest in attending an additional event to the three normally scheduled for the year. They wanted more opportunities to connect, engage in activities which interest them and strengthen the outcomes and aims of the YEC at a local, regional level.\nYEC members in the Central Adelaide and Mount Lofty Ranges region identified bird watching and animals as areas of particular interest. In response to this, the NRM Education team organised a one-day event for members with a range of activities based on these themes.\nThe venue chosen by the participating YEC members was Bonython Park (Tulya Wardli); a beautiful place to experience nature along the banks of the River Torrens. The event was attended by 11 students from eight different schools and it allowed them to reconnect and engage with nature through enjoyable and educational outdoor activities. These included animal-orientated icebreakers, get-to-know you activities, games and birdwatching activities.\nOn the day the weather was perfect, with the clear, sunny conditions allowing the members to use binoculars and identification charts to observe and record birds in Bonython Park and along the river. These habitat assessments compared the suitability of different areas in the park in providing habitat for birdlife.\nThroughout the year, YEC members each complete a sustainability project in their school or community and this regional event provided the perfect opportunity for them to share and celebrate their current progress or to troubleshoot any challenges they’d encountered.\nBoth the NRM Education team and the YEC members are looking forward to the final event for 2018, the Sharing and Celebration Forum, which will be held at Cleland Wildlife Park in November. The YEC members will showcase their projects and celebrate their sustainability achievements with family, teachers, other students and invited guests.", "pred_label": "__label__POS", "pred_score_pos": 0.9957241415977478}
{"content": "While it has been standard practice for decades to whisk newborns off to a bath within the first few hours of their birth, a new study has found that waiting to bathe a healthy newborn 12 or more hours after birth increased the rate of breastfeeding exclusivity during the newborn hospital stay.", "pred_label": "__label__POS", "pred_score_pos": 0.90694659948349}
{"content": "If you have not reset your password since 2017, please use the 'forgot password' link below to reset your password and access your SAGE online account.\n“In this Fourth Edition, Repko and Szostak have gone further to de-mystify the interdisciplinary research process. By providing students with guiding study questions within each chapter, adding extended advice on how to choose a complex research question, and illustrating that many of the strategies outlined in this text can be applied beyond the academy, they are more responsive to the needs of both professors and students.”\n“Repko and Szostak’s text remains a vital guide to interdisciplinary inquiry, with clear accounts of an ideal progression from initial idea through completed project. While oriented to all levels from undergraduates to professional scholars, the book ably serves as a text for doctoral students; it has helped them achieve profound contributions. The current edition expands on instruction regarding literature searches and research questions, while encouraging students to rely on their own creativity as novel approaches are conceived and interpretations of findings sought.”\n\"The Fourth Edition of Interdisciplinary Research offers improved clarity and usability, particularly for undergraduate researchers. Guiding questions at the beginning of each chapter encourage readers to remain focused, and newly incorporated examples of relevant, recent research demonstrate that interdisciplinary perspectives have the power to help us understand and shape the world around us—including people, policies, and even public spaces—for the better.”\n“The revised edition of Interdisciplinary Research is timely and well received! Literature on interdisciplinary research has increased and developed to include a synthesis theory and practice from around the world. This book is recommended for undergraduate and graduate students and those involved in interdisciplinary research. Instructors using this as a primary or supplemental text will find the pedagogical revisions helpful in challenging students to engage with the interdisciplinary research process. I highly recommend it.”", "pred_label": "__label__POS", "pred_score_pos": 0.978472888469696}
{"content": "Article\n21 October, 2020\nSky High Fine: ICO fines British Airways £20m for data breach\nThe Information Commissioner's Office (ICO) has fined British Airways (BA) £20m has fined British Airways - the biggest such penalty to date - for failing to protect data resulting in more than 400,000 of its customers' details being subject to a cyber-attack in 2018. However, the penalty is far less than the £183.4 million the ICO proposed in 2019.\nAn ICO investigation found that BA processed a significant amount of personal data without adequate security measures. These inadequacies resulted in a breach which BA failed to detect for more than two months. ICO investigators found BA ought to have identified weaknesses in its security and resolved them with security measures that were available at the time, which would have prevented the breach.\nAs the breach occurred prior the UK leaving the EU, the ICO investigated on behalf of all EU authorities as lead supervisory authority under the GDPR. The penalty and action have been approved by the other EU DPAs through the GDPR's cooperation process.\nThe Penalty Notice issued by the ICO outlines BA's co-operation with the ICO following it becoming aware of the breach and the subsequent efforts it made to mitigate the impact of the attack on those whose data was taken. Moreover, it outlines the arguments used by BA to reduce the sum payable. BA suggested that the ICO was both unjust and disproportionate in applying a formula, which took into account global turnover to calculate the original penalty. This argument was strengthened by the fact the data breach did not result in any special category data being taken. Additionally, the initial sum appeared to be excessive when compared to other well publicised fines issued by the ICO under the higher GDPR regime.\nThe ICO also considered BA's current trading performance and made specific reference to the impact of the COVID-19 pandemic on the travel sector. This resulted in the amended fine being reduced from £25 million to £20 million.\nWhile ICO has back peddled, this is still the largest fine ever issued by the ICO. It may not be the 4% of turnover which the initial penalty used, however, in the current trading conditions, £20 million is a significant outgoing for BA.\nThe process has highlighted the appeal mechanism available to data controllers and the potential tactics for reducing penalties. While the UK will soon be detached from the GDPR's cooperation process, the level of the fine will likely set a precedent in the UK for the coming years.\nFor more information contact Daniel Milnes in our Governance, Procurement & Information department via email or phone on 01254 222313. Alternatively send any question through to Forbes Solicitors via our online Contact Form.", "pred_label": "__label__POS", "pred_score_pos": 0.677189290523529}
{"content": "The total number of new reports of unemployment claims last week totaled 881,000, which is better than our estimate as the job market continues to make gradual progress during the coronavirus pandemic recovery.\nEconomists surveyed by Dow Jones were looking for a total of 950,000.\nThese figures reflect improvements in the labor market and changes in the Department of Labor’s methodology to address seasonal factors. It is possible that the total amount of unemployment claims was overstated during the epidemic period due to the unique circumstances associated with the coronavirus.\nThis figure has decreased compared to the previous week, but the total has not been corrected, making comparison difficult.\nHowever, the department noted that the state’s claims ending August 29 had declined compared to the previous week’s 1.11 billion. According to Ian Shepherdson, chief economist at Pantheon Macroeconomics, using the old methodology, the total would be 1.02 million.\nContinuing claims declined sharply, dropping from 1.24 million to 1254 million. The insured unemployment rate, which is the default calculation for those who are paid for the entire workforce, fell 0.8 percentage points to 9.1%.\nThe Department of Labor has changed the methodology that uses seasonal adjustments to account for the normal turmoil in the job market that does not apply much under virus-related conditions.\nThe unadjusted total, which continued to fall below the adjusted figure during the pandemic, was 833,352 last week, up almost 8,000 from the previous week.\nUnadjusted figures show that claims under the Infectious Disease Unemployment Assistance Program rose sharply to 759,482 last week, up 151,674. These programs generally provided benefits during the pandemic to people who were not eligible for unemployment insurance.\nIn short, the rate of layoffs is still very high, and it seems that the percentage of newly fired people looking for another job quickly is falling,” Shepherdson said.\nAt the state level, Florida saw the largest decline during the state at 12,312, while California saw the largest increase at 39,958.\nThe total number of workers receiving salaries was one week behind the current data, and 29.2 million in the week ending August 15, an increase of about 2.2 million from the previous week.\nThe number of claims is one day ahead of the government’s August non-farm payroll report. Economists expect 1.32 million more jobs to be created, and the unemployment rate will drop from 10.2% to 9.8%.", "pred_label": "__label__POS", "pred_score_pos": 0.7008458375930786}
{"content": "What is the Law Regarding Employment in Ottumwa?\nEmployment law refers to the body of laws in Ottumwa that regulate employees, employers, and independent contractors. Hiring procedures, wage disputes, and termination are some issues that are controlled by these laws. A general understanding of Ottumwa employment laws is required for both the employee and their employer.\n\"At-Will\" vs. Contract Employment Terms\nEmployment is typically considered to be \"at-will\", although at times the employer and employee might have an employment contract preventing termination before it expires. So long as the reasons are not in violation of law, either the employee or the employer may end the position at any time under an \"at-will\" arrangement. If an employment contract exists between the parties, state and federal laws will decide the validity and enforcement of the contract terms for people living in Ottumwa.\nAnti-Discrimination laws in Ottumwa\nDiscrimination is illegal at any time of employment such as hiring policies, wage distribution, and terminations, according to laws which apply to residents of Ottumwa. Residents of Ottumwa are regulated by laws which make it illegal to discriminate against members of specific categories. These categories include race, age, gender, national origin, disability, and religion.\nEmployment discrimination claims are often heard by an administrative agency like the EEOC. Furthermore, some attorneys are specialists in the discrimination field.", "pred_label": "__label__POS", "pred_score_pos": 0.5799044966697693}
{"content": "We present a method for the generation and coherent manipulation of pulsed quantum frequency combs. Until now, methods of preparing high-dimensional states on-chip in a practical way have remained elusive due to the increasing complexity of the quantum circuitry needed to prepare and process such states. Here, we outline how high-dimensional, frequency-bin entangled, two-photon states can be generated at a stable, high generation rate by using a nested-cavity, actively mode-locked excitation of a nonlinear micro-cavity. This technique is used to produce pulsed quantum frequency combs. Moreover, we present how the quantum states can be coherently manipulated using standard telecommunications components such as programmable filters and electro-optic modulators. In particular, we show in detail how to accomplish state characterization measurements such as density matrix reconstruction, coincidence detection, and single photon spectrum determination. The presented methods form an accessible, reconfigurable, and scalable foundation for complex high-dimensional state preparation and manipulation protocols in the frequency domain.\nquantum frequency combs auantum circuitry frequency domain analysis", "pred_label": "__label__POS", "pred_score_pos": 0.5659120082855225}
{"content": "Among the many trends that have accelerated due to COVID-19 is the need for associate technologies that are hygienic and safe, yet still offer employees convenience, functionality and access to relevant data. Retailers’ new goal is to maintain or even boost service levels while providing contactless experiences designed to keep consumers and workers safe.\nThis\nRetail TouchPoints Tech Guide explores the range of solutions retailers can offer their employees to handle commerce’s new realities. Key topics include: Advanced mobile solutions supporting curbside and contactless pickupand contactless transactions; Biometric solutions such as voice and facial recognitionfor touch-free identity verification; Workforce and task management solutionsthat allow for shift-swapping and can handle routine associate requests; and Training and communication solutions that support expanded safety and hygiene protocolsand ongoing education for associates.\nDownload the Tech Guide now!", "pred_label": "__label__POS", "pred_score_pos": 0.9637362957000732}
{"content": "Udaipur : In an endeavor to highlight the importance of nutrition for healthy living, Amway India, one of the country’s leading FMCG direct selling company, celebrated National Nutrition Week. The celebrations were in line withPrime Minister Narendra Modi’s recent announcement onobservingSeptember as the Nutrition month under the National Nutrition Mission and converting it into a people’s movement. The efforts are aimed towards promoting healthy living, encourage a balanced nutritional intake coupled with a regular fitness regime to ensure one’s holistic wellbeing.\nCommenting on the initiative, Ajay Khanna, Chief Marketing Officer, Amway India, said, “Today, health and wellbeing has taken precedence over everything else with a rise in awareness and appreciation for healthy living and strong immunity. Consumers are exploring newer ways to remain fit and healthy to further build awareness on this, we are creating innovative engagement platforms on how we can lead a better, healthier life by bringing nutrition centre-stage. At Amway, we strongly believe that smart healthcare provides unparalleled value to human life and believe that healthy living is a lifestyle choice and goes beyond just physical. In line with this,we are also celebrating September as the Nutrition month and has launched a unique monthlong initiative ‘Cook for a Cause’. Under the initiative, Amway India employees and direct retailers/sellers have pledged to cook and donate meals to the needy to support the cause of addressing Childhood Malnutrition in India.I am proud that every day our organization practice ways of ‘helping people live better, healthier lives’, which has been a core philosophy for over 60 years now.”\nCommenting on the initiative,Gursharan Cheema, Senior Vice President – North & South, Amway India, said, “Nutrition has taken thecentre-stage and caused a shift in consumer perception towards preventive healthcare and immunity supporting products. The need for healthy living and proper nutritional intake has gained momentum. With a strong legacy of 80 years in supplementation and dietary support, we are uniquely placed to address evolving consumer demands real-time. In collaboration with our direct sellers, specifically health enthusiasts, we are building communities, bringing people together to engage and exchange knowledge on healthy living, benefits of a balanced diet along with the body’s nutritional requirement for its proper functioning. Therefore, our National Nutrition Week celebrations were aligned withPM Modi’s vision of promoting holistic nourishmentin India. We are aligning all our efforts towards catering to the rise in demand for immunity supporting products and the growing awareness around the importance of nutrition among our direct retailer/sellers and their consumers.”\nAmway India organized an array of virtual activities and sessions spread over a week to promote holistic wellbeing and educate the direct retailer/sellers and their consumers. During the nutrition week, Amway India emphasized the importance of a balanced nutritional diet and fitness for a healthy life, through virtual engaging sessions on Yoga, heart health and the importance of proper nutrition for women in different age-groups. Additionally, there were curated sessions on the fun at home workout challenges, virtual health & beauty consultation and a celebration with Nutrilite. During these sessions, health experts also highlighted the benefits of Amway’s products under its marque brands Nutrilite to support holistic wellbeing.\nIn the recent past, Amway India has organized multiple digital activities to promote healthy living and spread awareness around the importance of optimal nutrition. The company in June commemorated International Yoga Day by organizing a one of a kind digital health and wellness festival focusing on yoga and holistic wellbeing. Amway India also launched its first-ever virtual fitness series, ‘Fit Hai to Hit Hai’ to promote and spread awareness about fitness and healthy living, through various engagement activities. Embracing the wave of digitization, Amway has scaled up these initiatives by making them virtual to reach a larger set ofdirect retailers/sellers\nAmway’s Nutrilite is a brand of choice among health enthusiasts as it caters to the evolving demands of consumers through product innovations in nutrition and herbal nutrition range. The Nutrilite range of dietary supplements are specially created for people who want to stay healthy and to help them bridge the gap in their daily requirements of vital nutrients.", "pred_label": "__label__POS", "pred_score_pos": 0.5854751467704773}
{"content": "You Can Collect Worker's Comp Benefits and Personal Injury Damages, Too\nAt Western States Law, P.C., we can ensure that you collect the full range of your damages, including pain and suffering, from the negligent person responsible for your injuries. Workers' Compensation benefits do not generally cover many of these losses. Our attorney's fee will be based only on your personal injury recovery, not your workers' compensation benefits.\nIf You Run Into Problems with Your Workers' Comp Claim, We Can Help\nIf your benefits are suspended, reduced, or terminated early, or if your employer's insurer disputes the extent of your injuries, we can refer you to a knowledgeable lawyer who can help resolve the problem. If your worker’s compensation claim proceeds smoothly, however, you may never need them to hire a workers' compensation attorney. We will pursue the at-fault driver for your injuries while working with, or negotiating with, your workers' compensation insurer who is certain to want reimbursement for benefits they paid to you or on your behalf.\nWe represent truck drivers, cab drivers, bus drivers, Uber and Lyft drivers, delivery drivers, construction drivers, and anyone else who was hurt in a truck or car accident while working. In some cases, passengers or crew members who weren't actually driving at the time of the accident will also be able to sue for personal injury damages while collecting workers' comp benefits. We also represent workers injured by third parties in non-auto related accidents such as slip and falls, dog bites, or other claims.", "pred_label": "__label__POS", "pred_score_pos": 0.5682821273803711}
{"content": "Diana has spent the past 20 years working with the technologies that power the world’s most demanding IT environments and is interested in how solutions based on those technologies impact the business. A native from Colombia, Diana holds an MBA from Georgetown University and has held a variety of regional and global roles with HPE in the US, the UK and Sweden.\nAdvancing on the journey started a few years ago, Hewlett Packard Enterprise has continued to transform during 2019. This journey has included both spin-offs and acquisitions; the next-Gen IT project – a significant effort to...\nIn our connected 24x7 economy, experiencing downtime for most applications has become cost-prohibitive for business, not only financially but also in loss of reputation. Minimizing downtime has long been a core tenet of IT teams...\nThis website uses cookies to improve your experience. We'll assume you're ok with this, but you can opt-out if you wish. Cookie settingsACCEPT\nPrivacy & Cookies Policy\nPrivacy Overview\nThis website uses cookies to improve your experience while you navigate through the website. Out of these cookies, the cookies that are categorized as necessary are stored on your browser as they are as essential for the working of basic functionalities of the website. We also use third-party cookies that help us analyze and understand how you use this website. These cookies will be stored in your browser only with your consent. You also have the option to opt-out of these cookies. But opting out of some of these cookies may have an effect on your browsing experience.\nNecessary cookies are absolutely essential for the website to function properly. This category only includes cookies that ensures basic functionalities and security features of the website. These cookies do not store any personal information.", "pred_label": "__label__POS", "pred_score_pos": 0.7841391563415527}
{"content": "No one likes to be told \"no.\" Whether it was your mom telling you that you couldn't have the latest toy when you were a kid or your boss saying you can't have that raise, \"no\" is usually not a word that evokes positive thoughts. So, why would you put it in your store displays?\nMany stores that sell fragile items will have signage accompanying them that read \"Do not touch\" or \"No touching\" or \"You break it, you buy it.\" These signs not only cause a negative reaction in the customer, they are plain rude.\nIf you feel your merchandise needs a warning, be mindful of how you phrase it. \"Please handle with care\" is a polite way of getting the message across, but even better might be something like \"We would be happy to assist you with these fragile items.\" A sign like this encourages customers to engage with store clerks, offering more opportunities for you and your employees to woo them with stellar customer service skills.\nYour employees can be polite and your store welcoming, but if you have negative signage on your display tables, you might be sending the wrong message to shoppers.", "pred_label": "__label__POS", "pred_score_pos": 0.9883560538291931}
{"content": "Toronto luxury sales to lead the nation as normalcy is restored in Vancouver; cautious optimism renews in Calgary while Montreal maintains healthy growth, forecasts Sotheby's International Realty Canada\nTORONTO, ONTARIO--(Marketwired - March 22, 2017) - Canada's market for residential real estate over $1 million will be led by the Greater Toronto Area (GTA) in the spring of 2017, with sales volume, velocity and pricing of the $4 million luxury segment projected to surpass previous years' record-breaking performance, according to Sotheby's International Realty Canada. Vancouver's $1 million-plus real estate market is anticipated to normalize in the coming months, while cautious optimism returns in Calgary. Montreal's market for real estate over $1 million is expected to continue its course of modest, healthy growth.\nData compiled by Sotheby's International Realty Canada in the country's four largest real estate markets foreshadow spring performance in 2017. The GTA experienced the greatest year-over-year gains in sales over $1 million (condominiums, attached and single family homes). In January and February 2017, sales volume increased 87% across the region, while sales in the city of Toronto rose 44%. During this time, sales of luxury real estate over $4 million soared 144% and 147% in the GTA and the city of Toronto respectively. In Montreal, $1 million-plus real estate sales increased 13% in the first two months of 2017 compared to the year prior, while Calgary's remained on par with 2017 levels. Vancouver sales over $1 million fell from historic highs by 45% year-over-year during this time, as sales over $4 million contracted 68%.\nCanada's top-tier real estate market continues to face unprecedented levels of uncertainty in spring 2017, absorbing the impact of previously introduced government policy, responding to shifting signals on potential new regulation, and moving with forceful geo-political headwinds on a continental and global scale. In spite of these macro-influencers, local market factors such as inventory levels, regional economic and job indicators, consumer confidence and hyper-local demand will continue to be the predominant forces influencing top-tier market performance in spring 2017.\n\"The Toronto real estate market has pulled into a league of its own, and we expect to see all-star performances across every luxury segment - single family and attached homes, as well as unprecedented performance in the luxury condominium market,\" said Brad Henderson, President and CEO of Sotheby's International Realty Canada. \"At the same time, rising Canadian consumer optimism will add positive colour to the markets in Vancouver, Calgary and Montreal in the coming months.\"\nKey National Influencers Vancouver\nVancouver's top-tier real estate market is expected to normalize this spring, following an action packed 2016 that saw sales over $1 million hold steady at a nominal 1% year-over-year decrease from record highs as the $4 million plus market posted 34% gains in spite of multi-pronged policy introductions aimed at cooling the market.\nSlackening sales at the start of 2017 signal a pending return to more moderate levels of market activity: residential real estate sales over $1 million declined 45% year-over-year to 531 units sold in January and February 2017, while sales over $4 million decreased 68% to 43 units compared to 133 units sold in the same period in 2016.\nSingle family home sales over $1 million fell 56% to 296 units sold in the first two months of 2017 compared to the same period in 2016. During this time, luxury home sales over $4 million stalled as real estate consumers hesitated and price expectations diverged between prospective buyers and sellers. Luxury single family homes over $4 million decreased 71% year-over-year to 35 units sold in January and February 2017 compared to 120 units sold during the same months of 2016.\nDemand for top-tier condominiums continue to reflect greater resilience than the market for single family homes. Buoyed by favourable demographic trends, downsizing baby boomers and millennial first-time homebuyers are boosting demand as they seek alternatives to detached homes. Condominium sales over $1 million in January and February 2017 decreased 28% year-over-year to 142 units sold, with five sales over $4 million reflecting a 55% decline from the same months the previous year. Persistent bidding wars within the top-tier condominium market suggest healthy demand in spring 2017.\nIn spite of imminent real estate market adjustments, Vancouver has boasted Canada's fastest growing metropolitan area economy for two straight years, and economic authorities have projected that the city will maintain this leading position into 2017 with a 2.8% expansion of the economy. Continued net migration, the lowest unemployment rate of Canada's largest cities and low vacancy rates will continue to sustain long term housing demand and consumer confidence in Vancouver's top-tier real estate market in the longer term.\nCalgary\nCautious optimism has returned to the city of Calgary's top-tier real estate market as sales activity stabilized leading into spring 2017. Sales over $1 million (condominiums, attached and single family homes) experienced 19% gains in 2016 over 2015, and early 2017 data indicates that this ground will maintain into the spring. As inventory contracted, 64 properties sold over $1 million during the first two months of 2017, unchanged from the same period in 2016.\nOf these transactions, 57 single family homes sold over $1 million, up a marginal 2% over the same period in 2017. Two condominiums sold over $1 million in the first two months of 2017 compared to one in 2016.\nStabilizing consumer confidence, however, remains fragile. The city's real estate market remains vulnerable to continued uncertainty in the oil and gas sector, elevated unemployment rates, wage uncertainty and net population outflow. The potential risk for new spring listings inventory to overtake demand also exists. With a buyers' market still entrenched in Calgary, and with conventional and top-tier market indicators still weak, sellers are cautioned to price and market strategically for current conditions through the course of the spring.\nGreater Toronto Area (GTA)\nSoaring activity in the first two months of the year foreshadow new heights for the Greater Toronto Area's top-tier real estate market this spring. In January and February 2017, the GTA (Durham, Halton, Peel, Toronto and York) market continued its record-setting sales streak, posting the strongest year-over-year gains of Canada's four major metropolitan markets for the period. Real estate sales over $1 million (condominiums, attached and single family homes) increased 87% to 3,043 properties sold, while luxury sales over $4 million increased 144% year-over-year to 66 units sold. During this time, sales over $1 million and $4 million in the city of Toronto increased 44% and 147% year-over-year, to 943 and 42 properties sold.\nThese gains follow a year in which GTA sales over $1 million and $4 million surged 77% and 95% in 2016 over 2015, while $1 million-plus and $4 million-plus sales in the city of Toronto increased 44% and 87% year-over-year.\nExceptional performance is anticipated for the high-end condominium market in spring 2017. Shifts in demographics, strong consumer and investor confidence, and comparative affordability in face of escalating single family home prices has propelled steep gains in demand resulting in heated bidding wars, and robust sales. Across the GTA, early 2017 condo sales volume over $1 million exceeded 2016 levels by 104% with 167 units sold. Within the city of Toronto, sales of condos over $1 million rose 85% year-over-year to 135 units. Four condos sold over $4 million during this time, all within the city of Toronto, up 33% compared to the first two months of 2016.\nThe $1 million-plus market for single family homes is projected to sustain heated growth this spring. In the first two months of 2017, the segment experienced 86% year-over-year gains in sales volume within the GTA and 38% gains in sales volume in the city of Toronto to 2,876 and 808 units respectively. The $4 million-plus luxury home segment is expected to surpass previous gains: in the first two months of 2017, sales volume rose 158% year-over-year to 62 units sold in the GTA, and 171% to 38 units sold in the city of Toronto.\nMontreal\nHealthy gains are forecast for the $1 million-plus real estate market in Montreal for spring 2017, following modest year-over-year gains in sales volume in the first two months of the year. In January and February 2017, real estate sales over $1 million increased 13% over the same months in 2016 to 88 properties (condominiums, attached and single family homes) sold. While single family home sales rose 10% year-over-year to 76 properties sold, condominium sales over $1 million rose 33% to 12 properties sold.\nTop-tier single family home sales are expected to see steady gains in sales volume and velocity from 2016 levels. The addition of new condominium inventory to the market with the recent completion of several new developments is projected to moderate prices, even as projected consumer demand is forecast to absorb additional supply.\nContinued growth in Quebec's provincial economy, buoyant consumer optimism and enduring political stability are set to sustain positive market conditions for top-tier real estate through the spring.\nTo download the 2016 Year-End Top-Tier Real Estate Report (released January 2017), please visit: http://sothebysrealty.ca/insightblog/2017/01/11/2016-top-tier-real-estate-report-2/\nAbout Sotheby's International Realty Canada\nCombining the world's most prestigious real estate brand with local market knowledge and specialized marketing expertise, Sotheby's International Realty Canada is the leading real estate sales and marketing company for the country's most exceptional properties. With offices in over 30 residential and resort markets nationwide, our professional associates provide the highest calibre of real estate service, unrivalled local and international marketing solutions and a global affiliate sales network of approximately 850 offices in 65 countries to manage the real estate portfolios of discerning clients from around the world. For further information, visit www.sothebysrealty.ca.\nDisclaimer\nThe information contained in this report references market data from MLS boards across Canada. Sotheby's International Realty Canada cautions that MLS market data can be useful in establishing trends over time, but does not indicate actual prices in widely divergent neighborhoods or account for price differentials within local markets. This report is published for general information only and not to be relied upon in any way. Although high standards have been used in the preparation of the information and analysis presented in this report, no responsibility or liability whatsoever can be accepted by Sotheby's International Realty Canada or Sotheby's International Realty Affiliates for any loss or damage resultant from any use of, reliance on, or reference to the contents of this document.\nContact Information:", "pred_label": "__label__POS", "pred_score_pos": 0.6938357353210449}
{"content": "A frustrated upset couple in a quarrel not talking after the fight, offended, stubborn, insulted, the jealous man sitting silently on the sofa at home with a sad, depressed, disappointed woman.\nDomestic violence can happen to anyone at any time. However, there are some risk factors that make it more likely in some homes than in others. If you are at risk, seek out care immediately from this life-threatening situation.\nIt’s important to remember that the behaviour of one domestic abuser can be significantly different from others. However, realizing that you are at risk could help you to realize, it is time to get help. Working with domestic violence advocates is the best way to get insight into your own circumstances.\nWhat Makes a Person More Likely to Abuse?\nConsider the following risk factors. These common risk factors for domestic violence can be a common sign it is time to get help. You could be in a situation where only one is true. Or, there could be numerous.\nThreats\nAbusers may threaten to take actions that would cause physical harm to another person. This includes threats against others, such as homicide, but also threats to themselves. Some threaten suicide as a tool to control the behaviours of others.\nStalking\nStalking does not mean just physically following a person. It also can include situations where the abuser follows the movements of an individual online, at work, with friends, and with family. They have a constant need to know where their victim is.\nPrevious Assaults\nStatistics indicate that individuals who have a history of domestic violence are likely to be violent again. However, some people have a history of assault that does not involve the same individual or may involve friends, strangers, children, or even pets.\nAccess to Firearms\nWhen there are firearms, or other types of weapons, in the home, there is an increased chance that an individual will use them against loved ones. Firearms can provide a tool for threatening.\nDepression and Mental Health Concerns\nMany individuals who struggle with mental health conditions, including depression, bipolar disorder, and anxiety are at a heightened risk to abuse others. This does not mean all individuals with depression are a risk.\nJealousy and Possessiveness\nMany abusers are continuously jealous of their victims. This can include constant questions about where they are and what they are doing. It also includes possessiveness in not wanting their victim to spend time with third parties.\nDrug and Alcohol Consumption\nDrugs and alcohol can be a tool to break down inhibitions, but in some, they can also create aggressiveness and encourage reckless behaviour. Individuals who are using drugs or alcohol are more likely to abuse than those that do not.\nLack of Respect for the Law\nIndividuals who have been involved with law enforcement previously, including those who have charges of abuse, are more likely to abuse than those who do not. If they do not respect police officers or any type of governing body, this can be a risk factor for abuse.\nPreviously Traumatized Individuals\nSome individuals struggle with previous traumas or violence impacting them from childhood. Those who are abused as children are more likely to abuse victims in their own adulthood.\nMany other factors can increase the risk of a person becoming an abuser. This includes things like unemployment, pet abuse, controlling behaviours, and destruction of property. Seeking out care is essential for any abused individual who sees these signs in their abuser.", "pred_label": "__label__POS", "pred_score_pos": 0.9755753874778748}
{"content": "RC develops tailor-made nutritional programs designed to provide the best suited response to dogs’ specific needs.\nFor dogs under treatment, we have developed a range of dietary foods which takes into account the risks associated to the dog's main pathology (renal insufficiency, food intolerances, oral hygiene, digestive, hepatic, or urinary disorders, joint mobility, obesity, recovery…). Satietogenic effect Contains a special blend of fibres that have satietogenic effect on dogs High protein A high protein content (113g/1000kcal ME) helps maintain muscle mass during a weight loss programme Nutrients balance Enriched with nutrients (protein, minerals and vitamins) to compensate for the effect of energy restriction ensuring during a weight loss programme Dental Health Contains specific nutrients which contribute to maintaining good oral health Ingredients COMPOSITION: dehydrated poultry protein, vegetable fibres, wheat gluten*, tapioca, maize gluten, hydrolysed animal proteins, chicory pulp, maize, wheat, animal fats, psyllium husks and seeds, minerals, fish oil, fatty acid salt, fructo-oligo-saccharides, hydrolysed crustaceans (source of glucosamine), marigold extract (source of lutein), hydrolysed cartilage (source of chondroitin). ADDITIVES (per kg): Nutritional additives: Vitamin A: 18800 IU, Vitamin D3: 1000 IU, E1 (Iron): 35 mg, E2 (Iodine): 3.5 mg, E4 (Copper): 7 mg, E5 (Manganese): 45 mg, E6 (Zinc): 136 mg, E8 (Selenium): 0.06 mg - Preservatives - Antioxidants. ANALYTICAL CONSTITUENTS: Protein: 30% - Fat content: 9.5% - Crude ash: 6.7% - Crude fibres: 15.5% - Metabolisable energy: 2668 kcal/kg. *L.I.P.: protein selected for its very high assimilation.", "pred_label": "__label__POS", "pred_score_pos": 0.7604308128356934}
{"content": "A proposal Sen. Chris Van Hollen (D-Md.) and House Ways and Means member Don Beyer (D-Va.) are expected to unveil this morning would generate an estimated $635 billion in revenue over a decade, according to the Tax Policy Center, by tacking a 10 percentage-point surtax on all income exceeding $1 million for single filers and $2 million for married couples filing jointly. (The surtax wouldn’t be indexed to inflation.)\nThe levy would apply to a taxpayer’s modified adjusted gross income and be assessed on all income including wages, salaries and investment income, such as from stock dividends and sales. Advocates have posted a web-based calculator that lets you fiddle around with policies to apply the money to, including education, health care and infrastructure.", "pred_label": "__label__POS", "pred_score_pos": 0.7159900665283203}
{"content": "Improving the retail CX during tough times 29 May 2020\nThe retail industry faces the challenge of delivering a consistent experience across all channels, including online and physical storefronts. It is also becoming increasingly critical to delivering tailored offerings that meet the needs and interests of individuals – a blanket approach to marketing is simply no longer sufficient.\nThe key to both of these elements is analytics, which in turn relies on ‘always on, always available’ data and 24/7 uptime. However, this can prove difficult during times such as now, during a lockdown. Without effective data management in place, including backup and recovery, this is an impossible goal.\nThe omnichannel experience\nWith the lines between online and physical stores blurring, it has become imperative for retailers to deliver what has become known as an omnichannel experience. Not only does the look and feel of an online presence need to mimic that of a store, but the entire experience should also be seamless.\nRetailers are therefore having to consider gathering and augmenting data from customers regardless of their chosen channel of interaction so that the data can be analysed, and intelligent insights gained.\nSubsequently, the intelligence can be used to deliver an optimised experience based on the individual needs and desires of the customer – a tailored customer experience that has become crucial to success in today’s highly competitive global marketplace. During times such as Covid-19, a competitive advantage is crucial to ensure that your business remains relevant and revenue streams continue.\nAll about the data\nData lies at the heart of this ability, which means that it needs to be always-on and always available with as close to zero downtime as possible. The entire appeal of online retail is its availability at any time, so any outages are detrimental. Couple this with the growing need for delivery of goods during this time. As a result, it is now imperative for retailers to understand what data they have, how it can be used, and how it can and should be protected.\nThis requirement is also being driven from a regulatory standpoint, with the imminent enforcement of the Protection of Personal Information (PoPI) Act legislating how customer data should be handled. In addition, retailers need to comply with the Payment Card Industry Data Security Standard (PCI-DSS) which regulates how customer payment information must be stored and processed.\nData protection is key to continuity\nData may become lost or corrupted for any number of reasons, from innocent problems like a failed hard drive or accidental deletion to more sinister issues like ransomware attacks. Regulations mean that such an instance could result in hefty fines, however protecting data is also critical for business continuity.\nWhen using analytics, artificial intelligence, tailored marketing and shopping experiences, access to data is critical. If for any reason the data cannot be accessed, the insights gained will be negatively affected, which in turn has a detrimental effect on the customer experience. This might mean a loss in competitive advantage, which in retail could be devastating.\nWhile off-the-shelf data management solutions are readily available today, given the critical nature of data for the retailer, it is often beneficial to seek the skills of an experienced data management provider. Managed services are hugely beneficial to retailers in assisting them to deliver the omnichannel experience and make the best use of centralised data and analytical tools in a cohesive, workable solution.", "pred_label": "__label__POS", "pred_score_pos": 0.6727968454360962}
{"content": "This paper investigates the motivations for local right-to-farm protection ordinances by estimating a logit model relating the adoption of these ordinances to various political, economic and demographic factors previously found to affect the likelihood of passage of farmland preservation policies. Results suggest that the probability of adopting right-to-farm policies increases with the size and political clout of the farm public and with incentives to promote right-to-farm. Adoption is not enhanced by environmental concerns, nor by factors known to encourage adoption of farmland preservation policies. These findings raise serious concerns about the long-run viability of protections afforded agriculture in urbanizing areas.", "pred_label": "__label__POS", "pred_score_pos": 0.7308816909790039}
{"content": "Apr 14 2020\n(Français) The rapid spread of COVID-19 has highlighted especially the vulnerability of Canada’s older adults and the potential impact of technological innovations to mitigate the spread of disease and minimize its disruptive impact on health and fulfillment of psychosocial needs. The 2020 Emerging Entrepreneur Award is part of AGE-WELL’s effort to address the public health", "pred_label": "__label__POS", "pred_score_pos": 0.7960559129714966}
{"content": "Date of this Version\n2017\nCitation\n2017 Des Med Devices Conf (2017). 2017 April ; 2017\nAbstract\nPercutaneous coronary intervention (PCI) is the most common revascularization procedure, in which, fibrocalcific plaques are found in 17–35% of patients undergoing PCI [1]. Numbers will rise with population aging and prolonged statin treatment. Calcifications often lead to stent under expansion and strut malapposition, with increased risk of thrombosis and in-stent restenosis [2]. Presence of calcium strongly inhibits stent performance, a well-documented metric for outcome [3]. The goal of this work is to develop the finite element models for inspecting the influence of the calcium arc extent on the stenting outcomes, such as the stress and strain distribution within the plaque, and the lumen gain following stenting. Finite element method is an effective tool to reveal the mechanism of the stent expansion and its interaction with target lesion, provide guidance for optimal clinical outcomes.", "pred_label": "__label__POS", "pred_score_pos": 0.7677727937698364}
{"content": "During the last 20 years, the advance of communication technologies has generated multiple exciting applications. However, classical cryptography, commonly adopted to secure current communication systems, can be jeopardised by the advent of quantum computers. Quantum key distribution (QKD) is a promising technology aiming to solve such a security problem. Unfortunately, current implementations of QKD systems show relatively low key rates, demand low channel noise and use ad hoc devices. In this work, we picture how to overcome the rate limitation by using a 37-core fibre to generate 2.86 Mbit s\n−1 per core that can be space multiplexed into the highest secret key rate of 105.7 Mbit s −1 to date. We also demonstrate, with off-the-shelf equipment, the robustness of the system by co-propagating a classical signal at 370 Gbit s − 1, paving the way for a shared quantum and classical communication network.", "pred_label": "__label__POS", "pred_score_pos": 0.9689697027206421}
{"content": "Dogs can eat oranges, which are rich in vitamins, citric acid, carotene and other nutrients. Appropriate feeding for dogs is beneficial to their growth and development. However, some dogs with weaker gastrointestinal tract and poor digestive tract are not suitable for eating oranges. Dog owners should pay attention to the state of the dog.", "pred_label": "__label__POS", "pred_score_pos": 0.9993017315864563}
{"content": "Reduces Federal Overreach of NCLB Increases Support for Teachers, Promotes Innovation in the Classroom Washington, DC - Colorado U.S. Senator Michael Bennet, a former superintendent of the Denver Public School District, today joined 80 senators to pass a long overdue fix to No Child Left Behind. The bill, also known as the Every Child Achieves Act, reauthorizes the Elementary and Secondary Education Act (ESEA), the chief federal law addressing K-12 education. It reforms many of the policies from No Child Left Behind, the previous version of the bill, while maintaining several key policies that have proved successful.\n\"Passing this bill has been a long time coming, and it's encouraging we were able to do it with overwhelming bipartisan support,\"\nBennet said. \"Chairman Alexander and Ranking Member Murray deserve credit for their leadership throughout this process.\"\nAs superintendent of the Denver school district, Bennet was often on the receiving end of well-intentioned but misguided policies coming down from Washington. As a member of the Senate Health, Education, Labor, and Pensions (HELP) Committee, he helped write the bill, securing dozens of provisions during the committee's consideration of the bill and during the debate on the Senate floor. Bennet's work on the bill stems from his time spent as superintendent and from dozens of conversations with parents, students, teachers, and administrators from around the state.\n\"The updates we passed in this bill address many of the problems with No Child Left Behind, while maintaining its strengths,\"\nBennet added. \"Part of what we've been trying to do is bring the lessons learned in Denver - from families, principals, teachers, schools, and kids - and now schools that we've had a chance to visit all over the state. The views of Coloradans are threaded throughout this bill. We've worked to re-empower those closest to our kids to ensure decisions are being made by those who know them best. And we've supported new opportunities for teachers and schools to expand the innovative strategies that are helping kids learn and grow in the classroom. While this bill isn't perfect, it includes many necessary tools to help our states, school districts, principals, and teachers to ensure our kids succeed.\"\nBennet's chief priorities focused on improving equity and addressing inequalities for teachers and students, reducing federal overreach while ensuring kids from low-income families receive access to a great education, encouraging innovation to meet our most persistent education challenges, and supporting rural schools to meet their unique needs in the face of limited resources.\nStudies show that teachers are the single most important factor in school in ensuring a child is receiving a great education. To that end, Bennet worked to include support for teachers to prepare and grow in their profession. Among the provisions he secured is a measure to create new leadership opportunities for teachers within schools, such as career ladders, mentorships, and academic coaching. Along with this provision, he secured a separate measure providing access to higher-quality teacher development that has proven to help teachers grow. He also included support for teacher and school leader residency programs modeled off of the Denver Teacher Residency Program.\nOne of the chief complaints about No Child Left Behind was its prescriptive, top-down approach to helping failing schools. Bennet worked to ensure the bill reduced federal overreach and promoted state-driven accountability systems, while ensuring we take steps to close the achievement gap and provide all kids with a quality education. While maintaining annual assessments and requiring state to break down that data to identify and track achievement gaps for different subgroups of students, Bennet passed an amendment to help reduce the burden of data reporting requirements for local school districts.\nOften the strategies proven to help students succeed are being developed in the classroom by innovative teachers. Bennet secured several measures to dedicate funding to help schools and districts expand those strategies to more classrooms and schools. Elements of Bennet's English Learning and Innovation Act and updates to the Charter School Program he championed were included in the bill. He also secured measures based on his bipartisan Social Impact Partnership Act to support early childhood education.\nFor a full list of provisions Bennet secured in the\nEvery Child Achieves Act, CLICK HERE.\n# # #", "pred_label": "__label__POS", "pred_score_pos": 0.6842533349990845}
{"content": "Our success helping healthcare brands grow stems from the insight that meaningful doctor/patient communications are a pivotal “point of convergence” between the HCP and patient information journeys.\nOur relentless focus on these make-or-break interactions informs a unique approach to segmentation and communications that closely considers both sides of the point of care conversation.\nWe call it perspectives-based planning, starting with discovery that uncovers the unique “digital DNA” of our audiences. Understanding the challenges, beliefs, and media sources that influence treatment decisions informs a marketing game plan tailored to break through and inspire action.\nDigital technology has essentially dissolved the boundaries between channel and content, placing the onus on media experts to create content that resonates for audiences throughout the media mix. They need to know your brand, your market, and your customers.\nAt CPM we create dynamic experiences optimized for each touch point along the treatment journey. We seamlessly partner with brand teams and their clinical, regulatory, and communications experts to ensure effective and compliant omnichannel activation.\nBringing top talent to your everyday business ensures your content is strategically on-point and tactically just right for the channels we choose. From SEM ad extensions to social media infographics, programmatic interactivity to landing page experiences, CPM is the brains behind the campaign.\nLearn how effectively your brand is getting found and gaining traction with your audience, and how you measure up against your full-stack audience activation and engagement potential.", "pred_label": "__label__POS", "pred_score_pos": 0.7696447372436523}
{"content": "Solvent cabinet\nThis article includes a list of references, related reading or external links,\nbut its sources remain unclear because it lacks inline citations. (October 2019) (Learn how and when to remove this template message)\nIn a chemistry laboratory a\nsolvent cabinet is a chemical storage cabinet or cupboard which is properly labeled and equipped, for the storage of solvents (especially those that are combustible). A solvent cabinet should be positioned separately from acid cabinet or base cabinet (used for storing acids and caustic bases respectively, as solvents are not compatible with these substances. (Some carts for transporting containers of chemicals come equipped with a built in solvent cabinet).\nA solvent cabinet must incorporate a number of safety features. It should be adequately ventilated, preventing the release of excessive fumes (being either sealed or vented). It should be equipped to contain fires and isolate the contents from sources of ignition, be grounded (to prevent sparks and static discharge).\nReferences[edit] PETER URBEN (22 October 2013). Bretherick's Handbook of Reactive Chemical Hazards. Academic Press. p. 381. ISBN 978-0-08-052340-8.\nThis chemistry-related article is a stub. You can help Wikipedia by expanding it.", "pred_label": "__label__POS", "pred_score_pos": 0.9904783368110657}
{"content": "Intra Strength is a comprehensive blend of 9 plant based amino acids designed to take your workouts to the next level. With added electrolytes, vitamins, minerals and superfoods, this powerhouse formulation works to support hydration, endurance, recovery and muscle repair.\nIf your struggling to make the most of your workout session, try fuelling yourself with PranaOn Intra Strength!\nPranaOn has formulated the ultimate amino acid formula to support muscle endurance and energy during workouts. Intra Strength is a powerful blend of Branched Chain Amino Acids and Superfoods designed to fuel your body with Nitrates, Electrolytes, Vitamins, Minerals & Antioxidants.\nFeaturing an effective dose of Fermented Branched Chain Amino acids in a 2:1:1 ratio, these three key aminos help play a direct role in muscle tissue repair and growth. Intra Strength also features Electrolytes from Coconut Water powder to promote rehydration, Vitamin C to combat the effects of oxidative stress (i.e. exercise) and Nitrates from Beetroot Powder to increase blood flow. To further support the immune system we have included L-Glutamine and Vitamins B6 and B12.", "pred_label": "__label__POS", "pred_score_pos": 0.5348778963088989}
{"content": "Compliance Confidence\nIRS Issues Relief From Distributing 1095-Bs IRS Issues Relief From Distributing 1095-Bs In Notice 2019-63, the IRS provides a welcome ACA reporting relief for employers and insurance carriers.\nAs with prior years, the IRS extended the deadlines to complete and distribute certain ACA reporting forms.\nForm To IRS To IRS To Employee To Employee 1095-C No Extension Jan. 31 Mar. 2 1095-B No Extension Jan. 31 Mar. 2\nThe IRS provided additional relief to entities required to distribute Form 1095-B. The insurance carrier typically issues the 1095-B for insured plans. There are also some employers that must complete and distribute the 1095-B if it is a non-ALE (applicable large employer) self-insured plan. The 1095-B is intended to report coverage for purposes of individual mandate compliance. However, beginning January 1, 2019, the individual mandate penalty was eliminated.\nFor these two groups reporting on the B forms, the IRS stated that it will not assess a penalty for failure to distribute Form 1095-B to participants in cases where the reporting entity meets the following requirements:\nProminently place a notice on its website with an email address, physical address, and telephone number, where individuals can contact the entity to request a copy of the 1095-B; and The reporting entity provides a copy of the 1095-B within 30 days of the request.\nImportantly, this relief does not apply to the employer mandate reporting requirement to complete and distribute Form 1095-C. ALEs must still furnish a copy Form 1095-C to its full-time employee by the extended deadline, including completing Part III that is required for self-insured plans.", "pred_label": "__label__POS", "pred_score_pos": 0.8712092041969299}
{"content": "Spectra collected by the Near Infrared Mapping Spectrometer (NIMS) onboard the Galileo spacecraft determined that a variety of near-infrared absorption bands overprint the dominantly ‘dirty’ H\n2O ice spectral signature of Callisto’s surface. One such absorption band centered near 4 µm has been attributed to the presence of SO 2 on Callisto, as well as on Europa and Ganymede. This 4-µm feature is thought to originate from S-rich species that are erupted from volcanoes on Io, ionized, and subsequently transported in Jupiter’s co-rotating plasma to the three icy Galilean moons. This process can explain the presence of the 4-µm feature on the trailing hemispheres of Europa and Ganymede. On Callisto, however, the 4-µm band is stronger on its leading hemisphere, hinting at a different origin for this band and/or different contributing species, possibly including carbonates. Complicating matters, the often low signal-to-noise and low resolving power (R ~40–200) of spectra collected by NIMS has limited our ability to interpret the origin and composition of the 4-µm feature.\nTo further investigate Callisto’s 4-µm band, we collected new near-infrared spectra with the SpeX spectrograph on NASA’s Infrared Telescope Facility (~1.9–5.3 µm, R ~2500), representing a significant improvement over the quality of the available NIMS spectra. These SpeX spectra show that the 4-µm feature is significantly stronger on Callisto’s leading hemisphere, supporting prior analysis of the distribution of the 4-µm feature detected by NIMS. The central wavelength position of the feature we detected is shifted to 4.02 µm, whereas the SO\n2 combination band ( ν 1 + ν 3) detected on Io is centered near 4.07 µm, casting doubt on SO 2 as the primary constituent contributing to Callisto’s 4-µm band. Our results are more consistent with other S-bearing species like H 2S 2 or HS 2, which could be formed by charged particle radiolysis of hydrogen sulfide (H 2S). Additionally, the spectral signature of carbonates like Na 2CO 3 can also provide a good match to the 4-µm feature. The clear hemispherical asymmetry in the distribution of the 4-µm band is consistent with in-falling dust grains from Jupiter’s retrograde irregular satellites, which should contribute material primarily to Callisto’s leading side. Alternatively, the species contributing to Callisto’s 4-µm band could be native to this moon and are exposed by dust particle collisions that spur regolith overturn, as well as larger impact events that sample greater depths into its subsurface.", "pred_label": "__label__POS", "pred_score_pos": 0.9088990688323975}
{"content": "Front cover; Copyright page; Contents; List of Illustrations; Acknowledgments; Introduction; 1. Parental Socialization in the Jim Crow South; 2. The Growth of White Privilege in Southern Schools; 3. White Children and the Culture of Segregation; 4. The Violent Reality of White Youth's Socialization; 5. Ritual and Performance in Southern Lynchings; 6. White Girls' Participation in Southern Lynchings; Conclusion; Notes; Bibliography; Index.\nSummary\nWhite southerners recognized that the perpetuation of segregation required whites of all ages to uphold a strict social order-especially the young members of the next generation. White children rested at the core of the system of segregation between 1890 and 1939 because their participation was crucial to ensuring the future of white supremacy. Their socialization in the segregated South offers an examination of white supremacy from the inside, showcasing the culture's efforts to preserve itself by teaching its beliefs to the next generation. In Raising Racists: The Socialization of White Child.", "pred_label": "__label__POS", "pred_score_pos": 0.9288405776023865}
{"content": "It is vitally important that vehicles are kept clean, at a level that minimizes the spread of the coronavirus, particularly between drivers’ change. Coronavirus is transmitted mainly by droplets (for example, from sneezing, coughing, or contamination from the hand to the mouth to the surface). Therefore, the areas of greatest risk are likely to be those in front of the. driver's mouth and nose, and those that touch. These include the steering wheel, gear lever, operating panel (radio, a/c conditioner, etc.), seat belts, mirrors, door handles, window controls, air conditioning controls, controls and displays of infotainment, the dashboard, the fuel cap and the keys.\nThese areas should be thoroughly cleaned at the end of each driver's service period, each. day or before each delivery, whichever comes first, using disinfectant wipes (which must be available / stored in each vehicle). The process: 1. Before cleaning, the driver must perform hand hygiene with alcohol gel. 2. Put on nitrile gloves. 3. Remove and dispose of general trash. 4. Clean vehicle areas described above, including keys. 5. Complete the cleaning log and view it on the dash visible through the windscreen. 6. Get out of the vehicle and lock it. 7. Take gloves off and dispose of them (for general cleaning, this is not a \"biohazardous waste\" and can be placed in an ordinary landfill). 8. Repeat hand hygiene with gel alcohol. Cleaning should be methodical and thorough. In the event that a vehicle is delivered after driver self-isolation or a confirmed COVID-19 infection, a deep cleaning may be necessary. If a new driver takes over a vehicle, and the cleaning log is not visible or it is not clear that cleaning has been performed, you should carry out hand hygiene, wear nitrile gloves, clean the vehicle as directed and then complete the registration. JAGUAR TEAM", "pred_label": "__label__POS", "pred_score_pos": 0.8397604823112488}
{"content": "Clauses that are parallel in form and meaning show processing advantages in ellipsis and coordination structures (Frazier et al. 1984; Kehler 2000; Carlson 2002). However, the constructions that have been used to show a parallelism advantage do not always require a strong semantic relationship between clauses. We present two eye tracking while reading studies on focus-sensitive coordination structures, an understudied form of ellipsis which requires the generation of a contextually salient semantic relation or scale between conjuncts. However, when the remnant of ellipsis lacks an overt correlate in the matrix clause and must be ‘sprouted’ in the ellipsis site, the relation between clauses is simplified to entailment. Instead of facilitation for sentences with an entailment relation between clauses, our online processing results suggest that violating parallelism is costly, even when doing so could ease the semantic relations required for interpretation.", "pred_label": "__label__POS", "pred_score_pos": 0.8530194759368896}
{"content": "Cotecna launches Atlas®, a pioneering land and property tax solution Cotecna Inspection S.A. is pleased to announce the launch of Atlas®, a solution designed to manage the property tax system on behalf of local governments. The service is based on cutting-edge technology and helps them boost their property tax revenue in a cost-effective manner.\nProperty tax is a valuable source of revenue for governments, yet they often lack the resources to fully benefit from it. Atlas® is a “one-stop-shop” which provides a comprehensive management support across the entire process from identifying and recording all properties via satellite imagery, to implementing targeted enforcement measures in line with local legislations.\nSébastien Dannaud, CEO, Cotecna Inspection S.A., comments: “Atlas is a modular and scalable solution that offers governments flexible processes, access to experienced professionals, advanced technology and stable funding. It is unique in that it brings immediate and tangible benefits to both the government and the taxpayer.”\nThe benefits of Atlas® include:\nIncrease in revenue through fair property valuation and optimised tax collection Revenue projection and budgeting based on reliable information High level of compliance and efficient enforcement mechanism Enhanced public awareness about the importance of property tax\nThis new offering confirms Cotecna’s ambition to diversify its portfolio of services aimed at government agencies and boasting the latest technology. The company which recently acquired a leading Indian laboratory, Shiva Analyticals, aims to increase its geographical coverage in key regions and expand its reach through organic growth and acquisitions.\nFor more information About Cotecna\nCotecna is a leading provider of testing, inspection and certification services. We offer solutions to facilitate trade and make supply chain safer and more efficient for our clients. Our trusted network of professionals and certified laboratories provide expertise across four key sectors: agriculture & food, government & trade, minerals & metals, and general cargo. Founded in Switzerland in 1974, Cotecna started off as a family business and has now grown to become a world-class international player with 3,000 employees in close to 100 offices across more than 50 countries.", "pred_label": "__label__POS", "pred_score_pos": 0.6991657018661499}
{"content": "France’s international digital strategy, presented by the Minister for Europe and Foreign Affairs on 15 December 2017, serves both as a framework and roadmap for the coming years. It is centred around three key focuses: governance, the economy and security.\nDigital technology is now a key issue for France’s foreign policy and public action as a whole, be it for the success of France’s economy in the global competitive sphere or for conditions of stability, security and power on a global scale.\nThese changes carry with them the risk of a deregulated, dangerous and closed digital sphere and as such it is time for France to define the principles for digital technology that it wishes to see succeed around the world. To achieve this, France must promote a model which is faithful to its values.\nThis model opposes the trends of compartmentalization, control of networks and destabilization which we are currently witnessing. Furthermore, this model does not resemble the model supported by large American and Chinese tech firms, it aims to provide greater protection by ensuring fundamental rights are respected, by supporting the principle of loyalty and by defending fair competition and taxation.\nIt is with this context in mind that the Ministry for Europe and Foreign Affairs has drawn up France’s International Digital Strategy (.pdf, in French). It has done so in consultation with all administrations concerned and by opening up its text to public consultation. The Strategy is focused on three key pillars: governance, the economy and security.\nIt represents a reference framework and diplomatic roadmap for the years ahead. This document enables France to promote a world which associates freedom and respect for standards. This world is situated in a European context as only the European Union has the ability to incarnate and convey this vision on the world’s stage.", "pred_label": "__label__POS", "pred_score_pos": 0.769758403301239}
{"content": "This text serves as a convenient one-stop resource on the pathogenesis, diagnosis and treatment of kidney diseases in context of advanced heart failure and presence of ventricular assist devices. Advances in managing heart failure, evidence-based practices and therapies are covered, along with the management of this unique and complex subset of patients. The book also provides insights into combined heart and kidney transplantation. Authored by leaders in nephrology, cardiology and transplantation, this book fills a critical knowledge gap in understanding and treating patients with acute or chronic dysfunction of the heart and kidneys and how one induces dysfunction in the other organ.", "pred_label": "__label__POS", "pred_score_pos": 0.9915473461151123}
{"content": "In summary:\nLast week, Amazon Web Services held its annual AWS re:Invent conference in Las Vegas, a learning event designed to reach stakeholders in global cloud computing. As part of the event, NFL commissioner Roger Goodell announced the league would be partnering with AWS on machine learning applications. Specifically, the partnership intends to help reduce traumatic head injuries by leveraging the expertise of AWS. According to Tech Crunch, meticulous data files and decades of video mean the NFL has a head start, and AWS can use the information to create meaningful simulations. These could help influence helmet design and identify necessary rule changes that would reduce concussion risks. A recent study of former football players uncovered that 87% of them suffered from degenerative brain disease. The NFL-AWS initiative is part of a larger approach to safety the NFL is calling “The Engineering Roadmap,” which is intended to move the helmet industry forward.", "pred_label": "__label__POS", "pred_score_pos": 0.920695424079895}
{"content": "T cell-based tracking of multidrug resistant tuberculosis infection after brief exposure. Richeldi L., Ewer K., Losi M., Bergamini BM., Roversi P., Deeks J., Fabbri LM., Lalvani A.\nMolecular epidemiology indicates significant transmission of Mycobacterium tuberculosis after casual contact with infectious tuberculosis cases. We investigated M. tuberculosis transmission after brief exposure using a T cell-based assay, the enzyme-linked-immunospot (ELISPOT) for IFN-gamma. After childbirth, a mother was diagnosed with sputum smear-positive multidrug-resistant tuberculosis. Forty-one neonates and 47 adults were present during her admission on the maternity unit; 11 weeks later, all underwent tuberculin skin testing (TST) and ELISPOT. We correlated test results with markers of exposure to the index case. The participants, who were asymptomatic and predominantly had no prior tuberculosis exposure, had 6.05 hours mean exposure (range: 0-65 hours) to the index case. Seventeen individuals, including two newborns, were ELISPOT-positive, and ELISPOT results correlated significantly with three of four predefined measures of tuberculosis exposure. For each hour sharing room air with the index case, the odds of a positive ELISPOT result increased by 1.05 (95% CI: 1.02-1.09, p = 0.003). Only four adults were TST-positive and TST results did not correlate with exposure. Thus, ELISPOT, but not TST, suggested quite extensive nosocomial transmission of multidrug-resistant M. tuberculosis after brief exposure. These results help to explain the apparent importance of casual contact for tuberculosis transmission, and may have implications for prevention.", "pred_label": "__label__POS", "pred_score_pos": 0.8440628051757812}
{"content": "Seroprevalence of Toxoplasma gondii Infection in Refugee and Migrant Pregnant Women along the Thailand-Myanmar Border. van Enter BJD., Lau Y-L., Ling CL., Watthanaworawit W., Sukthana Y., Lee W-C., Nosten F., McGready R.\nToxoplasma gondii primary infection in pregnancy is associated with poor obstetric outcomes. This study aimed to determine the seroprevalence of Toxoplasma infection in pregnant migrant and refugee women from Myanmar attending antenatal care in Thailand. A random selection of 199 residual blood samples from first antenatal screen in 2014-2015 was tested for Toxoplasma IgG and IgM antibodies. Seroprevalence of Toxoplasma infection was 31.7% (95% confidence interval = 25.6-38.4). Avidity testing in the three positive IgM cases indicated all were past infections. Multiparity (≥ 3 children) was significantly associated with higher Toxoplasma seropositivity rates. Seroprevalence of T. gondii infection in this pregnant population is similar to the only other report from Myanmar, where multiparity was also identified as a significant association. Toxoplasma infection is important in pregnant women. Nevertheless, in this marginalized population, this infection may be given less priority, due to resource constraints in providing the most basic components of safe motherhood programs.", "pred_label": "__label__POS", "pred_score_pos": 0.5201249122619629}
{"content": "Within two weeks, we co-created the solution and went live starting in the first week of August. This is a COVID-19 information helpline for 300 healthcare workers for the entire Kampala operations of Healthy Entrepreneurs.“\nWhat are the next steps for the solution?\n\"Since the solution is developed in the cloud and not specific to the Ugandan market, Healthy Entrepreneurs is planning to expand the solution to other countries in Africa, starting with Kenya.\"\nWhat is your take on this voluntary project?\n“I have learned a few lessons which I will take with me. For instance, innovation does not always need to be complex and time-consuming. Sometimes a simple innovation can make a huge difference. On a personal level, it was great to work with real users (i.e., patients, doctors and nurses) of healthcare solutions, which I don’t usually do.\nSecondly, further privacy and regulation in healthcare does not always have to be complicated. Necessity - in this context, a global crisis - makes everything possible. Decentralization can make it easier, but it is mostly less easy for bigger companies. When creating a solution, complex programming is not always needed. The fundamental understanding of business context and the ability to chose the right technology is more than enough. COVID-19 provides us with a lot of opportunities to make a real impact for the end beneficiaries, where technology is a key enabler in making a difference in healthcare solutions.”\n---\nTo have a better understanding of the work of Healthy Entrepreneurs, click here.", "pred_label": "__label__POS", "pred_score_pos": 0.6814371347427368}
{"content": "Belgian tax on securities accounts: also for expats? Belgian tax on securities accounts: also for expats?\nThe Belgian law implementing a tax on securities accounts (TSA) has been adopted back in February 2018. As a reminder, the TSA is a new tax levied at the rate of 0.15% on the total value of in-scope securities held by Belgian individual tax residents on securities accounts with Belgian or foreign banks; or foreign individuals on securities accounts maintained with Belgian banks.\nThe tax is not due on savings accounts or term deposit accounts. Investments held in a unitized life assurance policy linked to one or more investment funds (‘insurance wrapper’) or in a pension savings account are also exempt from the TSA.\nTo the extent that the average annual value of such securities exceeds € 500,000 per account holder, the TSA would be due. The € 500,000 threshold is calculated in accordance with a specific mechanism.\nThe following instruments would be considered to determine the total value :\n(i) stocks (both of listed and unlisted companies) and certificates of such shares;\n(ii) bonds (irrespective of whether they are listed) and certificates of such bonds; (iii) rights in mutual investment funds or shares in investment companies; (iv) cash bonds; (v) warrants (but not stock options).\nThe TSA follows in the footsteps of the Belgian stock exchange tax introduced already in 2017. Both tax regimes can have significant extraterritorial implications and foresee optional withholding mechanisms for non-Belgian financial intermediaries.\nYour Belgian bank will report the values of the securities and the tax due per account holder and deduct the tax from the account holder’s account. The tax is to be reported and paid by 20 December, starting this year. Overseas banks may also report and pay the tax via a fiscal representative in Belgium.\nBelgian non-resident taxpayers\nThe tax on securities accounts aims at securities accounts of private individuals. Securities accounts of legal entities (e.g. companies and non-profit organizations) are excluded from the scope.\nIn the first place, it applies to private individuals who are Belgian tax resident, including professionals, who during the reference year are the beneficiary of one or more securities accounts held with a Belgian or foreign intermediary (e.g. a bank).\nInitially it was the intention, as is the case with the Belgian stock exchange tax, to only tax securities accounts of Belgian residents. But eventually, it was decided to also apply the TSA on securities accounts held by non-resident taxpayers with a Belgian bank. Therefore, Belgian securities accounts of (foreign) expats, diplomats, EU officials, etc. who, on the basis of specific regulation, have the status of Belgian non-resident taxpayer, are also subject to the TSA.\nThis implies an equal treatment of Belgian resident and non-resident taxpayers, as both categories would be subject to the TSA.\nHowever, the question arises whether an extension of the scope of the TSA to non-residents will not simply lead to the transfer of their securities account(s) to another country. As non-residents can only be taxed at source, Belgium cannot levy the TSA on a foreign securities account held by a foreigner who qualifies as a Belgian non-resident taxpayer.\nAs a result, the taxability of Belgian securities accounts of non-residents may not result in significant additional tax revenue and entails a significant risk of capital and employment in (foreign) banks and asset managers active in Belgium focusing mainly on non-residents, being chased away.\nDouble tax treaty\nThe question is also whether the applicable double tax treaty does not prevent Belgium from imposing such a (wealth) tax on a Belgian securities account held by a non-resident. Assuming that the TSA can be qualified as a wealth tax, it needs to be verified first whether the applicable treaty does not prevent the Belgian tax authority from levying such a tax.\nFor example, for a Dutch tax resident, the double tax treaty between Belgium and the Netherlands (Article 22, 3 ° DTT) stipulates that assets such as securities on a securities account may only be taxed in the country of residence (i.e. the Netherlands) and thus not in Belgium.\nThis will undoubtedly lead to discussions with the Belgian tax authorities.", "pred_label": "__label__POS", "pred_score_pos": 0.5522047877311707}
{"content": "If you don't like public speaking, you aren't alone. Public speaking is a common anxiety.\nBut Presentr may be a solution to overcoming your fear. With the help of artificial intelligence, you receive a personal coach who helps you hone your speaking skills either via the app or desktop platform. With it, you can record yourself giving a speech, and the system will provide feedback, such as alerting you on whether you are speaking at a good volume or highlighting the words you commonly use.\nPresentr isn't only an option for individuals, though. Multiple employees can use the app, and managers can track their efforts and progress. Companies can also use the app during live training sessions to gather analytics on participants.\nThis tool offers various pricing plans. The free one gives users 60 minutes of recording time, an assessment score, and tips. An individual user plan ($9 a month) and a team plan ($15 a month) offer more robust features, while a custom plan could provide whole companies with the full spectrum of services.\nPresentr may be the solution to overcoming a fear of public speaking.", "pred_label": "__label__POS", "pred_score_pos": 0.6065982580184937}
{"content": "The Payment Services Bill - A New Regulatory Framework for Payments29 Nov 2018 LegisWatch\nThe Monetary Authority of Singapore (\"\nMAS\") currently regulates various payment services under the Payment Systems (Oversight) Act (\" PS(O)A\") and the Money-changing and Remittance Businesses Act (\" MCRBA\"). New payment models and services have since developed which create uncertainty over the regulatory scope of the PS(O)A and MCRBA and present new risks to be addressed. MAS conducted a public consultation on key proposals in the proposed Payment Services Bill (\" PSB\") on 21 November 2017 (our update on this can be accessed here) and issued its response to feedback received on the public consultation on 19 November 2018 (available here). On 19 November 2018, the PSB (available here) was read in Parliament for the first time.\nThe PSB will:\nstreamline payment services under a single legislative framework by combining the PS(O)A and the MCRBA;\nenhance the scope of regulated activities by taking into account developments in payment services; and\ntake a risk-based approach, i.e., it will calibrate regulations according to the risks posed by the various regulated activities by adopting a modular regulatory regime,\nand comprises two parallel regulatory frameworks:\na licensing framework for payment service providers; and\na designation framework for significant payment systems.\nThis Update highlights the key points of the Payment Services Bill.\nIf you would like information on this or any other area of law, you may wish to contact the partner at WongPartnership that you normally work with or the following partner:", "pred_label": "__label__POS", "pred_score_pos": 0.7635295391082764}
{"content": "Authors: Jessica Blythe and Chris Cvitanovic\nThe unique challenges presented by the Anthropocene to marine socio-ecological systems necessitate new approaches of knowledge production that are capable of integrating scientific disciplines to develop solutions that are desirable, equitable, and viable. Despite increasing rhetorical support for interdisciplinary marine research, however, significant challenges associated with doing interdisciplinary research persist, and undermine progress towards tackling and navigating the complex challenges faced by marine social-ecological systems. While a growing body of literature has sought to identify strategies for overcoming the documented barriers to building capacity for interdisciplinary research at the individual level, there is very little empirically derived guidance for how to build institutional capacity and structures that support interdisciplinary research, particularly for research organizations focused on developing solutions to marine sustainability challenges. To address this gap, in our new open access study published in Frontiers in Marine Science, we undertake an in-depth evaluation of the Centre for Marine Socioecology (CMS) in Tasmania, Australia, which brings together disciplinary expertise in physics, law, economics, biology, sociology and governance to solve the grand challenges facing the worlds coastal and marine environments. In doing so we identified five key organizational features that enable successful interdisciplinary marine research: 1) Support female leadership, 2) Forge partnerships outside of academia, 3) Develop impact-based performance metrics, 4) Cultivate a visible brand and 5) Seek long-term funding. We also identify strategies for achieving each of these five features. Future engagement with these five principles, including exploration of how they translate across contexts, scales, and geographies, will be critical for building the interdisciplinary research capacity that is required to tackle our most pressing scientific and societal questions.", "pred_label": "__label__POS", "pred_score_pos": 0.978107750415802}
{"content": "Extracting the underlying trend signal is a crucial step to facilitate time series analysis like forecasting and anomaly detection. Besides noise signal, time series can contain not only outliers but also abrupt trend changes in real-world scenarios. To deal with these challenges, we propose a robust trend filtering algorithm based on robust statistics and sparse learning. Specifically, we adopt the Huber loss to suppress outliers, and utilize a combination of the first order and second order difference on the trend component as regularization to capture both slow and abrupt trend changes. Furthermore, an efficient method is designed to solve the proposed robust trend filtering based on majorization minimization (MM) and alternative direction method of multipliers (ADMM). We compared our proposed robust trend filter with other nine state-of-the-art trend filtering algorithms on both synthetic and real-world datasets. The experiments demonstrate that our algorithm outperforms existing methods.\nJun-9-2019", "pred_label": "__label__POS", "pred_score_pos": 0.9854334592819214}
{"content": "Civil Rights\nBlock on Trump's Asylum Ban Upheld by Supreme Court\nEarlier this week the Tenth Circuit reviewed two sections of the amended Utah Sexual Solicitation Statute for First Amendment facial challenges by several escort service businesses. The district court upheld § 1313(1)(c), but found § 1313(2) unconstitutionally vague.\nThe Tenth Circuit, reversed in part, and affirmed in part, holding that the two sections were constitutional and did not infringe on appellants' First Amendment rights.\nIssue Preclusion\nAppellants argued that issue preclusion should apply because a predecessor sexual solicitation statute, previously held unconstitutional, had similar language. The court did not agree because the new statute was different, enacted separately, had distinct purposes, different effects and different definitions of \"sexual activity.\"\nWhether the Statute Is Over Broad\nThe court noted that the test for over-breadth is more stringent when criminal conduct is concerned, because of a state's legitimate interest in enforcing criminal laws. Appellants argued that the statute would prohibit conduct meant to be artistic or entertaining but the court did not agree. The court emphasized the fact that the statute required the acts coupled with the intent to engage in sexual activity for a fee. Without that intent, the conduct would not be considered criminal.\nWhether the Statue Is Vague\nLast, the court had to determine whether the statue was vague. The court noted that the statute gives \"fair notice of what conduct it prohibits.\" The fact that intent was required bolstered its position. The 10th Circuit stated the fact that surrounding circumstances could be used to infer intent was not problematic and cited examples such as the 10th Circuit Criminal Pattern Jury Instructions, and carjacking case law to illustrate its point.\nIt seems the Utah legislature got it right the second time around. After the predecessor sexual solicitation statute was found unconstitutional, it went back and drafted a statute that contained more specific language. This is a text book example of our balance of powers at play.\nRelated Resources:", "pred_label": "__label__POS", "pred_score_pos": 0.7419635057449341}
{"content": "A recent Comment, published in The Lancet Digital Health, has provided key insights into public perceptions on data sharing. Data sharing\nData science and artificial intelligence (AI) have the ability to transform how healthcare is delivered. The ongoing COVID-19 pandemic has been a key example of how global data sharing improves data-driven responses. Researchers have been able to rapidly collect, analyse, model and report data timely.\nNevertheless, data sharing in some cases is still a controversial subject. The most common concern is in relation to privacy. Despite efforts to ensure anonymity, malicious hackers remain a risk in re-identifying individuals. For many, the risk of data sharing outweighs the benefits.\nPrevious surveys have explored the range of views that the public hold about data sharing. It is clear that the public question the safety of their data. In particular, they are concerned about sharing their health data with third parties.\nA survey\nIn this study, researchers surveyed individuals across the UK and USA to examine public attitudes towards data sharing, data access and the use of AI in healthcare. The team selected these countries as comparators, as both are high-income countries with significant investment in advanced health information technology and data-driven care. They also wanted to observe whether the contrasting healthcare delivery systems would influence public attitudes.\nThe researchers developed an online YouGov survey. From this, they obtained data from 3,194 respondents aged >18 years across the UK (n=2,080) and USA (n=1,114).\nPerceptions on data sharing\nWhist more respondents were aware of electronic health records, their use was not widespread, particularly in the UK (14.3% vs 44.5% in the USA). Access to medical records was also low (59.0% in the UK and 70.1% in the USA). Nonetheless, many respondents still regarded access to their medical records as useful.\nWillingness to share anonymised health information was different depending on who was receiving it. Respondents were less willing to share their anonymised data to institutions using it for a more commercial purpose, e.g. insurance or tech companies. Older respondents were less trustful on sharing their personal information with any organisation compared to younger respondents.\nMost respondents, from both countries, felt happier to receive advice from a healthcare professional without assistance from AI (58.2% vs 54.8% in the UK and 51.8% vs 38.2% in the USA). However, a small majority of UK respondents, in contrast to the USA, felt happy to receive care from AI software if it was there just as a support for healthcare professionals. Younger respondents were more open to receiving advice from independent AI than older respondents.\nImplications\nThese results highlight that access and use of EHRs is not widespread. There are several barriers to accessing health records, including poor usability and interoperability, language barriers and overall mistrust in healthcare systems. Previous studies have shown that in the USA, ethnic minorities and lower income patients adopt EHRs less often than white and higher income patients. This emphasises the importance of tackling inequity in digital health. Patient involvement in the design of digital applications will likely be key in responding to the rapidly evolving expectations of digital services.\nAnother concern is the lack of trust. In the USA, over a third of patients were not willing to share their data with their doctor. It is clear that individuals are concerned about people profiting off their data. This was reinforced by the fact respondents were less willing to share their data with commercial end-users.\nThe team highlighted that these results represent a sharp shift in public opinion compared to the 2016 Wellcome Trust survey. In this survey, respondents were willing to share data with commercial organisations. This shift represents the increased public awareness of risks and consequences of data sharing with commercial industries.\nThe researchers emphasise the need for public standards that secure regulation and transparency of data use and sharing. They also suggest the importance of communicating this to patients clearly so that they understand how and why their data is being used.", "pred_label": "__label__POS", "pred_score_pos": 0.9915066361427307}
{"content": "You are here: A New Beginning EMAN'S STORY\nFor many Syrian refugees seeking shelter from the bombing and violence which has shattered their lives, Jordan is a sanctuary that allows them to focus once again on living, rather than struggling for survival.\nBut even away from the fighting, their horrific experiences can often continue to dominate their futures.\nEman had been happy in Homs, before the war touched the city. At 51 she was a recognised artist, with a popular gallery and a career as an art teacher – passing on her passion to younger generations of Syrians. Her husband was a successful businessman, they had a comfortable home and led prosperous lives.\nAll this was lost when they fled and, in Jordan, Eman could not stop crying. She was overcome with sadness at every moment, withdrew from her family and stopped eating or sleeping. She could not see a way forward.\nShe agreed to meet with an International Medical Corps case worker, and complained that her family's lives were ruined. They were struggling to find employment in their new surroundings, she could not face leaving their house and her children were suffering. Her son had reached Norway illegally and was struggling to adapt, while her daughter Mais – who had been studying law at Homs University – could now not complete her studies.\nIt was all too much for Eman; she had no energy, no desire to do anything and couldn’t even bring herself to complete the daily chores.\nShe too was lost.\nInternational Medical Corps’ case worker referred her to a psychiatrist and, just two days, later she was diagnosed with Major Depression Disorder.\nNow, through mental healthcare programmes funded with aid from the British people, Eman's recovery could begin. She was provided with medication and set a schedule of therapy sessions where she could explore the feelings she was struggling with. On the psychiatrist’s recommendation, she was also encouraged to begin volunteering as part of the NGO’s work in the country – providing her with a reason to get up in the morning and fill her day.\nEman began teaching again, providing young refugees with a creative outlet to express their feelings and views. Her work began to bring in money, and her family’s financial issues began to improve. Through encouragement from her case worker, the family applied for a scholarship at Al Yarmouk University for Mais – her daughter won the opportunity and returned to her studies. A more motivated Eman began phoning her son in Norway every day, providing the support he needed to begin moving forward – her days filled up and her depression lessened.\nToday Eman is enjoying her life once again.\nShe is more sociable, is part of the community there and able to engage in her art – the outlet which is so important to her. While the stresses that such refugees face still exist for her, she feels she can cope with them, with the support of those medical professionals who have encouraged her to regain her future.", "pred_label": "__label__POS", "pred_score_pos": 0.9285378456115723}
{"content": "December 9, 11-11:45 AM EDT\nPartnerships are critical to ensure a patient’s safe transition of care—especially during a public health emergency.\nEight months into the COVID-19 pandemic, an adequate PPE supply and access to testing are essential but not always enough. Equally important are our partnerships with providers of healthcare in our community.\nThis virus serves as a wake-up call. Let’s strengthen relationships and tackle challenges in a more committed, enduring way. Explore how Community Coalition Leaders connected with partners across the continuum to collectively address COVID-19 challenges.\nDiscover ways to: Harness the power of provider coalitions Establish a COVID-19 focused coalition Tackle critical areas as a coalition Invite Your Community Partners Share our flyer with your partners to ensure your community is engaged in this webinar.", "pred_label": "__label__POS", "pred_score_pos": 0.9993060827255249}
{"content": "Condominium and Cooperative Law in California\nCondominiums and cooperatives are forms of \"common interest\" communities.\nThese are communities in which each resident rents or owns a residential unit. The residential units are part of a larger building, or complex of buildings, which are owned by another entity, such as a corporation or association. The residents are accountable for the upkeep of common areas, such as lawns and walkways. Rather than personally tending to these things, residents typically pay a fee that covers these necessities.\nIf you simply look at a condominium or cooperative community, you likely won't be able to tell if it's one or the other.\nThis is due to the fact that there are no visual or physical characteristics that can distinguish one from the other. All the differences between them lie in the ownership arrangements that the residents have. With a condominium, the residents typically own their housing unit, and collectively own the land on which it sits. In a cooperative, the residents rent the units, and the land is owned by a single entity, either a corporation or other type of business association.\nLaws and Regulations Concerning Common Interest Communities in Redlands, California\nWhile there are a lot of Redlands, California laws that will affect the residents and owners of condominium and cooperative communities, there are few that are actually specific to such communities. Alternatively, they are mostly governed by laws of more general application, such as contract law, zoning laws, and landlord/tenant law.\nThe daily lives of residents, and what they are and aren't allowed to do in their residences, will be far more heavily impacted by rules and regulations that the homeowner's association, or the owner of the land, has imposed.\nThe land that common interest communities occupy is typically private property. Therefore, the owners of the property are free to make certain rules governing what is and isn't allowed on it. A good manager or owner will typically make every effort to strike a balance between residents' freedom to do what they want in their homes, and the rights of their neighbors to a safe, clean, and reasonably quiet living space.\nThis authority, however, has limits. There are some rules which landowners cannot impose. Most obviously, they can't bar people from renting or buying units based on their race, religion, or national origin in Redlands, California. This conduct is illegal under state and federal law, and can result in grave civil penalties.\nCan a Redlands, California Attorney Help?\nIf you have problems with your landlord, your homeowners association, or a neighbor, a reliable Redlands, California real estate lawyer may prove invaluable.", "pred_label": "__label__POS", "pred_score_pos": 0.5367587208747864}
{"content": "Abstract\nA spike protein mutation D614G became dominant in SARS-CoV-2 during the COVID-19 pandemic\n1,2. However, the impact on viral spread and vaccine efficacy remains to be defined. Here, we engineer the D614G mutation in the USA-WA1/2020 strain and characterize its effect. D614G enhances replication on human lung epithelial cells and primary human airway tissues through an improved infectivity of virions. Hamsters infected with the G614 variant produced higher infectious titers in the nasal washes and trachea, but not lungs, confirming clinical evidence that the D614G mutation enhances viral loads in the upper respiratory tract of COVID-19 patients and may increases transmission. Sera from D614-infected hamsters exhibit modestly higher neutralization titers against G614 virus than against D614 virus, indicating that (i) the mutation may not reduce the ability of vaccines in clinical trials to protect against COVID-19 and (ii) therapeutic antibodies should be tested against the circulating G614 virus. Together with clinical findings, our work underscores the importance of this mutation in viral spread, vaccine efficacy, and antibody therapy. ASJC Scopus subject areas General", "pred_label": "__label__POS", "pred_score_pos": 0.7836933135986328}
{"content": "The Brihanmumbai Municipal Corporation (BMC) on Thursday announced the ban of firecrackers as the state government requested them to. Considering the Maharashtra Government’s appeal to citizens, for avoiding the use of firecrackers this Diwali, initially, BMC has drafted a notice to silence them.\nEarlier, this major step was taken by the Madhya Pradesh government, as Chief Minister Shivraj Singh Chouhan, requested the citizens to avoid the use of firecrackers and discourage the foreign goods that could harm the environment. As the pollution is rising day by day, the government is fearful that increased smoke will result, in poor air that can harm the covid patients.\nWhile the whole world is combating this virus, new difficulties may arise with the growing pollution. However, in view of the present scenario, the senior officials may review the draft within two days while counseling with the state before announcing it. Earlier States like Madhya Pradesh, Delhi, and West Bengal had banned the use of firecrackers.\nMunicipal Commissioner Suresh Kakani said, “We cannot confirm anything yet as no decision has been taken. However, as soon as the government will give us orders we will initiate the request. We are following up on the issue.” Additionally, a civic official stated that such drafts have been made by the government of Rajasthan as well. Commissioner warned that any sought of active participation in the firecracker business will result in penalization.\nThe increased risk of infections and other severe symptoms, such as asthma or lung failure can be injurious for children and senior citizens. The State Environment Minister, Aditya Thackerey, has asked the BMC to delve into the matter while exploring various possibilities to silence the use of firecrackers. Thus, less amount of smoke in the air and decreased sound during the festival can be peaceful for many Covid-19 patients.\nUnder the Epidemic Diseases Act, the government and the BMC can ban the use of firecrackers for safeguarding many lives that are under threat.\nAs the BMC officials are waiting for the government orders, the state has appealed to people to discourage the use of firecrackers which can lead to noise pollution. As Mumbai was the state with the highest number of covid cases till October, therefore, the state is not willing to risk the life of its citizens just for the sake of a festival.\nEven if one applies sense, it could exasperate the health situations which could be fatal. Keeping all the concerns and repercussions in mind, citizens must avoid the use of firecrackers. Thus, considering the bleak Covid-19 conditions, the second wave of this virus may hit the nation.\nThe public health minister Rajesh Tope proposed the idea of a ‘Cracker – Free Diwali’. Organizing a meeting with the Covid-19 task force, the minister stated, “We discussed several topics in the cabinet. Additionally, the use of crackers was also discussed and we appeal to the general public not to burst crackers at any cost.” The smoke will settle in the atmosphere and could continue in the form of fog that can last through the winters.", "pred_label": "__label__POS", "pred_score_pos": 0.799435555934906}
{"content": "This new project, a partnership between NLGN, Barrow Cadbury Trust, Carnegie UK Trust, and Power to Change, aims to capture and share the good practices that have emerged during the Covid-19 pandemic, and find ways to embed and build on them.\nIf you work for a local authority, public service, community group or simply have a story to share, they would be interested to hear from you.\nIf you would like to contribute your experiences to this research, contact Simon Kaye, skaye@nlgn.org.uk.", "pred_label": "__label__POS", "pred_score_pos": 0.8957656025886536}
{"content": "Now that the tax season has passed and the demands of the holidays are far behind us, we can take a moment to reflect on the blessings of Independence Day. As advisors, we have the opportunity to help our clients pursue their unalienable rights to life, liberty and the pursuit of happiness. Now, perhaps more than ever, is a perfect time to revisit your clients’ current financial plans to ensure they are focused on the right objectives for the future. Here are just a few ideas to help you initiate these discussions with your clients.\nHard times for boomers The baby boomer generation currently faces financial challenges no generation has previously encountered, including pension terminations, unabated healthcare costs, growing uncertainty about government programs such as Medicare and Social Security combined with decreased personal savings rates in an era of increased life expectancy. These realities will call upon most boomers to significantly adjust their lifestyles to accommodate the possible loss of a job, healthcare coverage or personal savings.\nDespite these ongoing challenges, with your wise counsel baby boomers can still find comfort and security as they plan for retirement. First and foremost we must convince clients to live below their means. This will leave them with income now to save for the future. Some of the most valuable elements of any strong financial plan are built on a foundation of life insurance and annuities.\nA safe solution Annuities deliver guaranteed income clients can’t outlive, while life insurance creates tax-free capital to assure that their debts and obligations will not outlive them. If the current downturn in the economy has taught us anything, it is that life insurance and annuities were built for times like these.\nLife insurance provides clients’ heirs with the confidence and peace of mind that there will be dollars free of income-, capital gains- and, when properly structured, estate-tax, for their loved ones and beneficiaries. It is important for advisors to realize financial planning, especially during retirement is relative. Our current economic challenges affect all clients, regardless of their income or financial portfolio.\nAs challenging as it might be, it’s our duty to help our clients muster the confidence to believe the future is in their hands, not the government. Together we can help them build a lifetime of independence that our founders fought so valiantly for.", "pred_label": "__label__POS", "pred_score_pos": 0.5708798170089722}
{"content": "Heaton, Pam F..2009.Assessing musical skills in autistic children who are not savants.Philosophical Transactions of the Royal Society B: Biological Sciences, 364(1522),pp. 1443-1447.ISSN 0962-8436[Article]\nDescriptions of autistic musical savants suggest that they possess extraordinary skills within the domain. However, until recently little was known about the musical skills and potential of individuals with autism who are not savants. The results from these more recent studies investigating music perception, cognition and learning in musically untrained children with autism have revealed a pattern of abilities that are either enhanced or spared. For example, increased sensitivity to musical pitch and timbre is frequently observed, and studies investigating perception of musical structure and emotions have consistently failed to reveal deficits in autism. While the phenomenon of the savant syndrome is of considerable theoretical interest, it may have led to an under-consideration of the potential talents and skills of that vast majority of autistic individuals, who do not meet savant criteria. Data from empirical studies show that many autistic children possess musical potential that can and should be developed.", "pred_label": "__label__POS", "pred_score_pos": 0.7469697594642639}
{"content": "I’ve walked past the oak tree a few times, since meeting Finola, feeling her absence there, and wondering about isolation.\nA few weeks ago, the sound of suitcase wheels, outside on the pavement, caught my attention, hooking into a longing for freedom; their squealing protests echoing an over-laden world in lockdown.\nIt stopped beneath my window, creating a silence that stepped into absence, loneliness and then curiosity as a woman’s quiet northern lilt ushered her presence into the room through the open window.\nI lent into the alcove to look at her. She was busy rummaging in a holdall that was resting on top of her black suitcase, eventually, pulling out a large stainless-steel flask and passing it to the shop’s security guard. I recognised that sense of familiarity, a habit, and I felt the loss of those habits that coat-hanger the day.\nIt was a travelling bag, her essentials to hand, and she quickly pulled out a jumper to put on over the small rucksack on her back; preparing for an evening chill that would reach into a cold night.\nShe came back at more or less the same time every evening, keeping a distance from other homeless people who were congregating close to the shop. I wanted to imagine her life; how locked-in worked for those locked-out, but the lack of sureness and a foothold in my everyday imagining seemed unlikely.\nSadly though, being stranded in a city with relatively quiet empty streets, imagining seemed unnecessary. The sleeping spaces, often created behind buildings near heat sources, were more visible on the streets, and sitting places – homing into where people were coming and going. Competition for money and food fierce at times, as people tried to secure what they needed.\nWalking in the streets, I found myself looking for her, but we eventually met in a park of fields, a couple of miles away. She was sitting, leaning against an oak tree. I stood looking at her as she took in the warmth of the sun as it fell, reaching under the canopy of new leaves and trailing blossom as the blackbirds were singing. The suitcase lying open, her belongings cascading onto the grass as though she had been rummaging again; an arresting image.\nShe looked tired and weather-worn but relaxed, and it felt as though we shared a sense of being at home in green open spaces. She looked like she’d fallen asleep in the grass at some point, with bits of dry twigs and leaves snagged in her hair, and earth caught under her fingernails.\nAs I stopped to say hello, an insect landed in my eye and she quickly offered me her wipes; it eased us into a conversation that felt a bit awkward to start with but seemed to find its own way. I don’t know what I expected, but it largely settled on the the burning issue of the epidemic.\nI suppose, I thought her interest might rest with the practical everyday aspects of it, but she wanted to discuss the wider societal implications. Whilst we chatted a bit about ourselves, there was a feeling that we came from different worlds, but that Covid-19 seemed to question the reality of that.\nThere was a sense of beauty in our unexpected connection, as with her name, Fonola, that derives from Fionnuala – the carrier of Gaelic legends.", "pred_label": "__label__POS", "pred_score_pos": 0.6921001672744751}
{"content": "Samburu and Marsabit Counties in Kenya are home to several pastoralist tribes, among them the Samburu, the Borana, the Rendille and the Gabra. These tribes are distinct in language and customs, but one similarity they share is that they continue to practice Female Genital Mutilation/Cutting (FGM/C) and Child, Early and Forced Marriages (CEFM) despite Kenyan laws outlawing both in 2001.\nAn average of 76% of women across these tribes underwent FGM/C and 70% were married before they were 18. Each tribe is led by elders who make the decisions for the rest of their community and play a crucial role in maintaining these harmful practices.\nThe practices are linked; when a girl (typically between 8-15 years old) undergoes FGM/C, she is considered ready to be married off, often to a much older man and is expected to drop out of school once she is married.\nThrough funding from USAID and our donors, we created Koota Injena — which translates to “Come let us talk” in the Borana language — where we promote the use of community dialogues to end FGM/C and CEFM in 40 communities who identify as Samburu, Borana, Rendille and Gabra in Samburu County and Marsabit County", "pred_label": "__label__POS", "pred_score_pos": 0.9923739433288574}
{"content": "Our lifestyle is made up of choices. From the food we eat to the words we use, they all have a rippling affect in our lives and those around us. The next challenge is to be intentional with the words you choose - spoken, written and thought. Take the following into consideration:\nBe Positive\nChoose To vs. Have To/Can't\nWant To vs. Have To\nCan vs. Can't\nChoice vs. Should\nWant vs. Don't Want\nFor example, I am allergic to dairy and gluten. You will rarely hear me say, \"I can't have that.\" I would more likely say, \"I choose not to eat that.\" Another example, I explained to Crystal (my dear friend) a challenge I was having at work. She observed the language I was using and found me consistently using \"don't want.\" Bringing this to my attention, she encouraged me to identify and put my energy (thought and action) to what I DO want.\nI challenge you to use your words - spoken, written and in thought - with intention for your greatest good and that of others.", "pred_label": "__label__POS", "pred_score_pos": 0.9500356316566467}
{"content": "This paper focuses on the present condition and future of the professoriate and is part of a long-term study on how the academic profession is changing, now more rapidly than at any time in memory. These dramatic shifts have led to a deep restructuring of academic appointments, work, and careers. The question now looming is whether the forces that have triggered academic restructuring will, in time, so transform the academic profession that its role—its unique contribution—is becoming ever more vulnerable to dangerous compromise. Whether the academic profession is able to negotiate successfully its role in the new era—to preserve core values and to ensure the indispensable contributions of the academy to society—remains to be seen.", "pred_label": "__label__POS", "pred_score_pos": 0.983870267868042}
{"content": "Well that’s not what I said. I’m saying that when we stop judging we can make adult decisions about what to do next. By calling them “bad” and shaming them, we’re just staying in relationship with them. When we see them for what they are—mentally ill people—we can take appropriate action, such as walking away, or removing the authority from them (or encouraging or requiring them to get treatment for PTSD). When we cannot see them for what they are, we turn them into these scary bogey-people that we don’t know what to do with.", "pred_label": "__label__POS", "pred_score_pos": 0.9585191607475281}
{"content": "Abstract\nThis study assessed the usefulness of passing euthanized Atlantic salmon\nSalmo salar smolts through an Archimedean screw turbine to test for external damage, as compared with live, actively swimming smolts. Scale loss was the only observed effect. Severe scale loss was 5·9 times more prevalent in euthanized turbine‐passed fish (45%) than the live fish (7·6%). Additionally, distinctive patterns of scale loss, consistent with grinding between the turbine helices and housing trough, were observed in 35% of euthanized turbine‐passed smolts. This distinctive pattern of scale loss was not seen in live turbine‐passed smolts, nor in control groups (live and euthanized smolts released downstream of the turbine), which suggests that the altered behaviour of dead fish in turbine flows generates biased injury outcomes.", "pred_label": "__label__POS", "pred_score_pos": 0.9741072654724121}
{"content": "The explosive growth in online video streaming gives rise to challenges on efficiently extracting the spatial-temporal information to perform video understanding. Conventional 2D CNNs are computationally cheap but cannot capture long-term temporal relationships; 3D CNN based methods can achieve good performance but are computationally intensive, making it expensive to deploy. In this paper, we propose a generic and effective Temporal Shift Module (TSM) that enjoys both high efficiency and high performance. Specifically, it can achieve the performance of 3D CNN but maintain 2D complexity. The central idea of TSM is to shift part of the channels along the temporal dimension, which facilitates information exchange among neighboring frames. TSM can be inserted into 2D CNNs to achieve temporal modeling at the cost of zero FLOPs and zero parameters. On the Something-Something-V1 dataset which focuses on temporal modeling, we achieved better results than I3D family and ECO family using 6X and 2.7X fewer FLOPs respectively. Measured on P100 GPU, our single model achieved 1.8% higher accuracy at 8X lower latency and 12X higher throughput compared to I3D. Remarkably, our framework ranks the first on both Something-Something V1 and V2 leaderboards upon this paper's submission.", "pred_label": "__label__POS", "pred_score_pos": 0.7180131673812866}
{"content": "detail - Regional Programme Australia and the Pacific Online-Seminar This portlet should not exist anymore Details\nThis year’s dialogue will take place in a slightly altered, virtual format – the overarching theme of ‘\nCybersecurity in Crisis Times- A Way Forward for Europe and Australia’ will be addressed through three separate interactive discussion sessions with speakers from Europe and Australia.\nThe Covid-19 pandemic has highlighted not only the interconnectedness of the world but also the associated vulnerabilities. This requires us to look at how we manage global interdependence, particularly in the area of cyberspace, as a politically contested space shaped by hyper-connectivity and lack of overarching global governance. The topic for the entire dialogue/discussion series hence centres around multilateral and multi-stakeholder engagement and the potential for increasing cooperation as the COVID-19 pandemic has widened the attack surface for cyber operations. While this first discussion in the series will focus on global cyber norms, subsequent sessions (one later in August and one in September) will respectively be dedicated to joint responses to large-scale cyber incidents and the EU approach as well as AI governance.\nWe are supported in the organization by three experts from the Stiftung Neue Verantwortung – a Berlin think tank at the intersection of technology and society – who will chair these sessions.\nThis event will be held under Chatham House Rule (not open to the public). Experts are invited to these discussions as part of a selected group to allow for the opportunity to actively engage and share insights.\nSession One\nThe opening discussion will be on\n‘Covid-19 and the road to global cyber norms: The case of banning cyber operations against public health infrastructures’.\nInput speakers from the European and Australian side are:\nMs Johanna Weaver, Head of the Australian delegation to the UN Open-ended Working Group on cyber norms, Department of Foreign Affairs and Trade, Mr Wolfram von Heynitz, Head of the Cyber Policy Coordination Staff, German Federal Foreign Office Mr Lukasz Olejnik, independent adviser and researcher Mr Bart Hogeveen, Head of Cyber Capacity building, International Cyber Policy Centre, Australian Strategic Policy Institute\nThe session will be chaired by Alexandra Paulus from the Stiftung Neue Verantwortung (SNV)\nThematic Overview: Following multiple cyber operations targeting public health infrastructures, various groups of states and non-state actors condemned such attacks and even advanced concrete proposals for establishing a norm banning cyber operations against public health infrastructures. This case study raises interesting questions and implications regarding the process of establishing global cyber norms at the United Nations and beyond. For example, what steps would be necessary to make such a norm sufficiently robust? How is this relevant for European-Australian cooperation in this matter?", "pred_label": "__label__POS", "pred_score_pos": 0.5657958984375}
{"content": "Suppliers and Quality Agreements Managing global supplier audits to allow more efficient monitoring of suppliers across sites, while improving supplier-related quality processes and saving time and effort. Generica QMS Suppliers and Quality Agreements module addresses challenges such as potential supplier inspection, supplier quality and approval process, agreement management, as well as external supplier audit planning and execution. This module assists the quality team in ensuring a valid and up-to-date agreement for each product and each supplier, as well as controlling individual suppliers while maintaining a global perspective.\nGenerica QMS is used for managing suppliers and quality agreements on a global basis. A part of the wide responsibility manufacturers in the Life Science industry have for the quality of their producs is verifying the quality delivered by their suppliers. This includes conducting audits to approve the suppliers, performing periodic assessments, tracking all suppliers quality occurrences, closely managing quality agreements, verifying commitments, and so on.\nManaging suppliers and agreements with Generica QMS avoids duplications resulted form suppliers that supply multiple sites, improves process quality, and saves time and effort for the site quality teams. Generica Suppliers and Qulity Agreements module addresses challenges ranging from potential supplier inspection, to the quality approval process, agreements management all the way to external supplier audit planning and execution.\nOne of the things make Generica QMS an intuitive and friendly systme for users is its seamless integration with standard tools such as Word, Excel and PDF. This allows users to remian in their familiar work environment when performing their daily activities, and not needing to leave their relevant document. The majority of the actual work can be easily performed from those common tools, while they are being leveraged by Generica to support Generica QMS functionality and processes. This increases user productivity, while helping to ensure regulatory compliance.\nGenerica Suppliers and Quality Agreements includes a pre-defined solution and best practices, but can also be easily configured to meet company’s specific processes and needs.", "pred_label": "__label__POS", "pred_score_pos": 0.7701754570007324}
{"content": "Secure Newly Remote Privileged Users\nSecure remote access for your privileged users who must access critical systems and data\nDeemed Critical Infrastructure? Get a free six-month license from Prianto\nAs more IT administrators are required to work remotely, securing and monitoring their activities is extremely important, particularly when accessing critical infrastructure and sensitive systems.\nOne Identity Safeguard for Privileged Sessions (former Shell Control Box solution) enables you to control, monitor and record privileged sessions (including for those administrators working from home), remote vendors and other high-risk users. It serves as a proxy, inspecting application-level protocol traffic and rejecting any traffic that violates the protocol – making it an effective shield against attacks. We realize that you are being asked to rapidly transition to a remote workforce. This can be particularly challenging with your privileged users who now must work from home but still access privileged systems and data to keep your organization moving forward. The Cybersecurity and Infrastructure Security Agency (CISA) recommends that as organizations explore various alternate workplace options that they should enhance system monitoring to ensure early detection of threats and abnormal activity.\nOne Identity can help meet these recommendations and smooth migration to supporting an expanded remote workforce, including privileged users. We have the solutions and experience to help organizations that are deemed critical infrastructure enhance security through additional monitoring with Safeguard for Privileged Sessions.\nSafeguard for Privileged Sessions compliments your existing remote-access system by recording and monitoring access to privileged or critical systems. Sessions are monitored in real time and, if unusual or unwanted behavior is detected, actions can be taken immediately, including sending an alert or terminating a session. You can even enable policies that restrict clipboard access and SFTP to limit the transfer of data to the users’ remote machine.\nSafeguard for Privileged Sessions is a turnkey appliance, which means installation and configuration are simple and quick. Operating at the network level, it is transparent to the user and yet it enables them to continue using client applications and workflow processes. Your organization will begin to experience value within a day and full implementation typically takes around three to five days.\nFree Six-Month License\nOrganizations that are deemed critical infrastructure qualify for a free, six-month license to help secure your environment. This license may be extended if the crisis continues. Once you register, our technical team can demonstrate the capabilities of the One Identity Safeguard solution and discuss the architecture as well as the installation process.\nRegister for the program Watch our video on securing privileged remote access Learn more about Safeguard for Privileged Sessions\nWhat can we do for you?\nWe are looking forward to your contact!\nTo keep yourself up-to date, click here to subscribe to our newsletter!", "pred_label": "__label__POS", "pred_score_pos": 0.6487043499946594}
{"content": "The epidemiology of norovirus gastroenteritis in China: disease burden and distribution of genotypes. Zhou H., Wang S., von Seidlein L., Wang X.\nWith the improvements of sanitation and nationwide safe water supply the occurrence of bacterial diarrhea declined remarkably, while viruses became the leading causes of acute gastroenteritis (AGE). Of these viruses, noroviruses (NoVs) are responsible for a considerable burden of gastroenteritis, especially in children < 2 years and elderly ⩾ 65 years. NoVs circulating in the Chinese population are antigenically highly diverse with the genotype GII.4 being the dominant strain followed by GII.3. Given the widespread contamination in environmental sources, and highly infectious nature of NoVs, vaccination would be the desirable strategy for the control of NoV infections. However, a better understanding of acquired immunity after infection, and a reliable immunological surrogate marker are urgently needed, since two vaccine candidates based on virus-like particles (VLPs) are currently moving into clinical evaluations in China.", "pred_label": "__label__POS", "pred_score_pos": 0.7616447806358337}
{"content": "On 24 September the European Commission issued a\nDigital Finance Package, which includes the Digital Finance Strategy for the EU.\nAs the Covid-19 pandemic spread through Europe, the uptake on new digital financial solutions increased while the need for a widespread adoption became evident. With the Digital Finance Package, the European Commission is aiming to tackle the challenge of promoting digital finance services while addressing the risks that may arise for users and for the stability of the financial market.\nThe Commission has identified\nfour priorities to guide digital transformation until 2024: Harmonization of the Digital Single Market for financial services to allow financial firms to scale up across borders, eliminating many restrictions for FinTech providers. This includes regulation on electronic identification and trust services for electronic transactions, extending the latter to the private sector. Empowerment of digital innovation through a regulatory framework that promotes the responsible useof digital financial services. The main focuses of the European Commission are c rypto-assets and distributed ledger technology(e.g. blockchain), further developed in the proposal for Regulation on Markets in Crypto-assets. The proposal also addresses the use of critical ICT providers(e.g. cloud service providers) by crypto-asset providers. Enhancement of data-driven innovation and data-sharing across sectors, supporting a Single Market for Data. Enforcement of the principle “same activity, same risk, same rules” between new market players and existing financial institutions. The European Commission aims to safeguard the Union’s financial stability through a proposal for a new Framework for digital operational resilience for the financial sector.\nThis proposal intends to:\nGuide financial institutions through ICT risk management; Establish rigorous resilience testingfor ICT systems used in these institutions; Create awareness in financial supervisors for cyber-attacksand for the dependencyof finance firms on ICT service providers; Create a report mechanismfor ICT incidents in the sector.\nAt VdA, our interdisciplinary Team of FinTech experts, composed of members from the ICT and the B&F practice areas is delivering rigorous and strategic legal advice to prepare our clients for the new challenges arising from the Digital Finance Package.", "pred_label": "__label__POS", "pred_score_pos": 0.9243394732475281}
{"content": "Are you easily distracted, unable to keep focus and continuously failing to complete tasks? ADD is formulated to specifically address these issues. It is a combination of nutrients aimed at stabilising blood sugar, increasing Adrenal function, raising blood pressure and eliminating brain fog, ADD, autism and poor concentration.\nIngredients: 5HTP, Calcium D-Pantothenate (B5), Chromium Polynicotinate, DMAE, Grape Seed Extract, L-Glutamine, Oatstraw (Avena Sativa), Pine Bark Extract, Quercetin, Reishi Mushroom Extract, Vanadyl Sulphate, Vitamin B Complex, Zinc Gluconate", "pred_label": "__label__POS", "pred_score_pos": 0.8931207656860352}
{"content": "Entertainment law offers services such as contracts and copyrights that are particularly designed for pieces of entertainment like books, movies and visual arts. It is an imminent concern for those who work in the entertainment industries that their work is never plagiarized or exploited. Artists have certain intellectual property rights in Missouri, which are safeguarded in part by copyright and trademark laws.\nWhat is A Copyright?\nA party holding a copyright can exclusively produce a given form of entertainment, requiring any others who want to use it to get consent first. In order to comply with the entertainment laws in Missouri, someone seeking to use your copyrighted material must negotiate and acquire a license or contract from you first. A copyright does not last forever, and all procedures surrounding copyrights are controlled by state entertainment laws. You will want to familiarize yourself with the specifics, whether you want to simply protect your property rights or you are interested in selling licenses for your work.\nWhat is a Trademark?\nA symbol or other notable visual characteristic that people associate with a brand is a trademark. Visual cues are key in the entertainment industry to create product recognition. Trademarks, unlike copyrights, do not expire. However, they must be registered with the U.S. patent and trademark office. Once you have your trademark, creating brand identity becomes much easier.\nHow Can a Missouri Attorney Help?\nDeciding whether you need a trademark or copyright is often a decision best made with the advice of an attorney in Cameron that has experienced in entertainment law. The filing process in Missouri can also go more smoothly with an attorney to guide you.", "pred_label": "__label__POS", "pred_score_pos": 0.5335454344749451}
{"content": "By Howie Berman, executive director, American Council on the Teaching of Foreign Languages.\nImagine being rushed to the emergency room after a car accident or a heart attack. You’re in terrible pain, perhaps confused and disoriented. The last thing you want to have to worry about at that critical moment is the ability to communicate with a doctor. Yet, for many patients in America, this is the unfortunate reality.\nAccording to 2017 Census Bureau data, a record of 66.6 million U.S. residents spoke a language other than English at home. By 2010, the Limited English Proficiency (LEP) population, those individuals who are not fluent in English, rose to 8.7%, up from 6.1% from 1999. In those 10 years, the U.S. saw an influx of over 11 million LEP individuals, driving the need for qualified language services.\nIn an increasingly globalized world, the healthcare industry is lacking in world language skills, and the need for multilingual healthcare professionals is rapidly growing.\nHealthcare providers should be capable of communicating with patients in a way that allows them to make informed decisions about their health. Effective communication with patients is critical to the safety and quality of treatment, but in modern society that’s not always the case.\nACTFL’s\nMaking Languages Our Business report shows the results of a national survey among 1,200 upper-level managers and human resources professionals with knowledge of their organization’s foreign language needs. The report was conducted by Ipsos Public Affairs, with support from Pearson LLC and Language Testing International. The report points to a critical and growing language skills gap across multiple business sectors—and the U.S. healthcare system is not immune to the challenges that this gap presents. Language Barriers in Healthcare\nAccording to the report, the healthcare and social assistance sectors are more likely than any other industry to have foreign language needs exclusively for the domestic market. Additionally, employers in healthcare are also the most likely of the sectors represented in the report to expect an increase in demand for foreign language skills in the next five years.\nWhile there are several laws in place designed to ensure healthcare organizations can communicate to patients in multiple languages, not all organizations adhere to them.\nTitle VI of the Civil Rights Act of 1964, Americans with Disabilities Act (ADA) and Affordable Care Act (ACA) all require federal healthcare programs such as Medicare or Medicaid to provide patients with interpretation/translation services if they have a language barrier or sensory impairment.\nIf a medical organization neglects to seek assistance from a qualified interpreter or does not provide translated written materials, and it results in harm to the patient, this constitutes medical malpractice.\nPatient Risk\nThe consequences of ineffective communication between physicians and patients can have devastating results. A physician who cannot communicate with a patient due to a language barrier may deliver delayed or incorrect medical care. The Federal Agency for Healthcare Research and Quality recognizes Limited English Proficient (LEP) patients are at higher risk for injury during medical treatment than those fluent in English, often resulting in greater harm to the patient, and cost to both the patient and healthcare provider. Further, language miscommunication with LEP patients leads to treatment delays, patient confusion, more extended hospital stays and even lawsuits.\nIt’s evident a change is needed. How then can healthcare organizations build a pipeline of multilingual employees and ensure all patients have access to high-quality care?\nBridging the Language Skills Gap\nOne way that healthcare professionals can work to solve the skills gap is by conducting language needs analyses within their healthcare institutions. Identify linguistic strengths and weaknesses in the organization and define current and future language needs. A language audit will help create clear goals and measurable outcomes for attaining the necessary language capacity.\nAdditionally, making world languages a strategic focus throughout the recruitment process is also a critical step to addressing the need for multilingual employees. Set hiring targets for employees with foreign language skills based on organizational goals.\nProviding care in a patient’s native language prioritizes patient safety, facilitates a critical human connection, enhances money-saving efficiency and decreases liability. By addressing the language skills gap, U.S. healthcare employers will not only benefit from a pipeline of prospective multilingual employees but also improve the patient experience and overall health of Americans in the process.", "pred_label": "__label__POS", "pred_score_pos": 0.6557377576828003}
{"content": "Terry Laughlin and I, as well as many TI Master Coaches, have discovered that teaching/learning correct shoulder and scapular articulation can significantly accelerate the process of mastering efficient, effective and enduring swim technique while diminishing the risk of injury.\nLike the martial arts, TI Swimming movements are sourced from your pelvic core – specifically your Don Tien – as it is known in T’ai Chi. All bio-mechanically efficient movements start deep in the center of your body.\nMastering the scapular and shoulder articulation in all phases of the freestyle swim stroke assures the correct mediation between your powerful pelvic core and your more delicate extremities.\nNow you are swimming with your core, not your hands! This is the key to efficiency and endurance.", "pred_label": "__label__POS", "pred_score_pos": 0.8287841081619263}
{"content": "Abstract\nA 34-year-old woman had simultaneous photorefractive keratectomy and corneal collagen crosslinking with riboflavin-ultraviolet-A irradiation for the treatment of progressive pellucid marginal corneal degeneration in both eyes. No intraoperative or early postoperative complications occurred. Twelve months postoperatively, the uncorrected visual acuity was assessed at 20/40 in both eyes compared with counting fingers preoperatively. The corrected visual acuity also improved from 20/50 and 20/63 to 20/25 and 20/32 in the right eye and left eye, respectively. Corneal topography revealed a significant improvement in both eyes. Despite the encouraging results, longer follow-up is necessary to confirm the stability of the results.\nASJC Scopus subject areas Surgery Ophthalmology Sensory Systems", "pred_label": "__label__POS", "pred_score_pos": 0.9982897639274597}
{"content": "Over 250,000 people who work for an employer who has voluntarily signed up to the \"real living wage\" are set for a pay boost of 20p to £9.50 an hour and by 10p in London to £10.85.\nThis is not to be confused with the compulsory National Living Wage, which is currently £8.72 an hour for anyone over the age of 25.\nThe increase is designed to help workers and families through the pandemic. Over 800 more employers have accredited with the Living Wage Foundation since the start of lockdown, including Tate and Lyle, Network Rail, Capital One and the All England Lawn Tennis Club. They join a network of almost 7,000 employers across the UK who are already paying this recommended rate to ensure all staff earn a wage that meets the real cost of living, and covers everyday needs.\nThe increase should be implemented as soon as possible but in any event within six months.", "pred_label": "__label__POS", "pred_score_pos": 0.501950740814209}
{"content": "Abstract:\nPromising research on DNA repair signaling pathways predicts a new age of anti-tumor drugs. This research was initiated through the discovery and characterization of proteins that functioned together in signaling pathways to sense, respond, and repair DNA damage. It was realized that tumor cells often lacked distinct DNA repair pathways, but simultaneously relied heavily on compensating pathways. More recently, researchers have begun to manipulate these compensating pathways to reign in and kill tumor cells. In a striking example it was shown that tumors derived from mutations in the DNA repair genes, of BRCA-FA pathway, were selectively sensitive to inhibition of the base excision repair pathway. These findings suggest that tumors derived from defects in DNA repair genes will be easier to treat clinically, providing a streamlined and targeted therapy that spares healthy cells. In the future, identifying patients with susceptible tumors and discovering additional DNA repair targets amenable to anti-tumor drugs will have a major impact on the course of cancer treatment.", "pred_label": "__label__POS", "pred_score_pos": 0.6252230405807495}
{"content": "Morristown Airport's Economic Impact Airports are a crucial part of New Jersey’s overall economy. As such, the New Jersey Department of Transportation (NJDOT) periodically reviews and updates the New Jersey State Airport System Plan (NJSASP). Revisions to the economic impacts of its system airports are included to maintain accurate data on which to base business decisions made by the State, municipalities, airport community and other entities. Airports play a vital role in New Jersey’s local and state economies, not only providing transportation for residents, businesses and visitors; but also serving as key economic drivers. All airports included in this study contribute jobs, payroll, and output to the local economy. Based on the data collected, each airport was evaluated to determine the impacts on the economy of New Jersey. Below is the economic impact of Morristown Airport from the 2016 NJDOT report.\nThe Morris County Economic Development Corporation, a division of the Morris County Chamber of Commerce, is a partnership of business and government dedicated to growing the economy of Morris County, New Jersey through programs and services that result in business attraction, creation, retention, and expansion, and to assist government in managing growth for the benefit of present and future generations.", "pred_label": "__label__POS", "pred_score_pos": 0.5020110011100769}
{"content": "The coronavirus pandemic has drastically changed the K-12 landscape across the U.S. As school administrators, teachers, staff and students navigate the new and challenging academic year ahead, effective communication and engagement will be more vital than ever.\nThis comprehensive guide outlines how a critical communication and collaboration platform can improve information flow, expedite response efforts and allow school communities to adapt to any situation that may arise on campus or remotely.", "pred_label": "__label__POS", "pred_score_pos": 0.9994139671325684}
{"content": "Tenaga Nasional Berhad (TNB), Malaysia’s largest electricity utility, has commissioned an enterprise energy management (EEM) system from Power Measurement of Canada to help optimise power quality and reliability across its national distribution network. Under the terms of the agreement, Power Measurement’s Malaysian agent, SFG Technology (M) Sdn Bhd, will supply, install, test and commission the EEM system, which consists of a network of ION® intelligent energy meters and web-enabled software.\nThe EEM system will automatically monitor and report on power quality conditions at each substation. As a detailed source of both real-time and historical information, it will help staff identify potentially disruptive conditions, investigate the source of faults, and restore power quickly after an outage. This technology will also provide operations and planning staff with the information to evaluate network performance through monthly and annual power quality reports. Additionally, the EEM system is expected to accommodate TNB’s benchmarking objectives by helping to analyse harmonics, and routinely monitoring compliance with international power quality standards such as EN50160, SEMI F47 and ITIC.", "pred_label": "__label__POS", "pred_score_pos": 0.7005881071090698}
{"content": "Update on Injured Ontario Workers and Bill 148\nInjured workers who currently receive benefits under the provincial Workplace Safety and Insurance Board (WSIB) should be aware of proposed changes to Ontario’s minimum wage laws.\nIn mid-July 2017, the Ontario Ministry of Labour announced that it intended to create more opportunity and security for workers through its Bill 148, which is the proposed Fair Workplaces, Better Jobs Act, 2017.\nAmong the proposed changes is an increase in the minimum wage across the province, to $15 per hour, and taking steps to ensure part-time workers are paid the same hourly wage as full-time workers.\nTo examine the impact of these proposed amendments, the province subsequently undertook a two-week consultation on Bill 148, and established a Standing Committee on Finance and Economic Affairs. The Committee travelled to 10 communities to hear from residents and business owners, and conducted a clause-by-clause review of the Bill.\nThat Committee heard from advocacy groups for injured workers and specifically those who are currently receiving WSIB benefits for wage loss due to workplace related injuries or illnesses. Those groups’ concern focused on the interplay between the WSIB’s practice of “determining” or “deeming” the wage-levels of injured workers who would otherwise be employed and the level of WSIB benefits that those workers are entitled to receive.\nSpecifically, these advocacy groups noted that if the minimum wage is increased to $15 per hour as proposed by Bill 148, then injured workers currently on WSIB benefits could see those benefits decrease, based on the Board’s determination of the level of income such workers might otherwise earn were it not for their work-related illness or injury. The full impact of the proposed minimum-wage increase on existing WSIB benefit entitlements was the subject of a formal submission to the Standing Committee.\nIt should be emphasized that the changes proposed under Bill 148 – which affect a broad range of employment and labour issues have not yet been finalized. On August 21, 2017, the Standing Committee adopted at least some of the suggested improvements of the stakeholders’ on various topics. Those amendments will be reported back to the Ontario Legislature when it resumes sitting on September 11, 2017.", "pred_label": "__label__POS", "pred_score_pos": 0.9608267545700073}
{"content": "Dive Brief: Wheelabrator is suing Baltimore County, Maryland for failing to deliver a contractually-mandated minimum of 215,000 annual tons of waste to the company's Baltimore incinerator, as first reported by the Baltimore Sun. According to the lawsuit, Baltimore County provided 65,813 fewer tons last year than stipulated by a 2011 contractual amendment. As of April 5, the county has reportedly sent 2,223 tons to the Wheelabrator facility and has announced plans to curtail its business before the contract term is up. \"The damages the County will incur for failure to deliver the waste guaranteed to be delivered by it in the contract are more than $32 million,\" said Wheelabrator spokesperson Michelle Nadeau in a statement. \"We are confident the court will find in our favor, unnecessarily costing Baltimore County taxpayers as much as $46 million in total contract savings and damages.\" Dive Insight:\nThe complaint, which was filed last Thursday in the Baltimore County Circuit Court, seems likely to exacerbate the already-fraught relationship between Wheelabrator and local officials in the Baltimore area. Following sustained public backlash against Wheelabrator's local incinerator, the Baltimore City Council voted unanimously in February to approve emissions standards far outstripping the state's current requirements — a move widely regarded as an attempt to close the facility.\nOpposition against the 30-plus-year-old incinerator has also found increased political support at the state level. Earlier this year, the Maryland Senate voted to remove WTE as a qualified source of renewable energy — a designation that allows the facility to reap over $1 million in subsidies each year from utility customers. That \"green energy\" label has since been restored in a final bill awaiting Gov. Larry Hogan's signature.\nAccording to the filed complaint, Baltimore County's original 2009 contract, which lacked a minimum tonnage requirement, was amended in 2011 to stipulate that the county deliver a minimum of 215,000 tons of waste annually in exchange for waste disposal price reductions, a one-time payment of $2.15 million by Wheelabrator and other conditions.\n\"We regret that multiple attempts to resolve this issue through good-faith negotiations — including a cost reduction that would have saved Baltimore County more than $14 million over the remaining term of our contract — have been unsuccessful,\" Nadeau said in a statement. \"We continue to believe it is in both parties' interest to resolve this matter amicably.\"\nWheelabrator has maintained that the city's new emissions requirements could effectively shut down the facility, and efforts to change the company's state renewable energy status aren't likely to taper off. Still, many industry stakeholders continue to broadcast optimism regarding the future of WTE in the U.S. — during a presentation at this year's NAWTEC conference, Macquarie's recent purchase of Wheelabrator was framed as a long-term play destined to weather present scrutiny.\n\"Wheelabrator has been around a long time — it's one of the leading energy platforms in the world,\" said Paul Mitchener, a managing director at Macquarie Infrastructure and Real Assets, at the event. \"It has a mix of UK and U.S. energy assets, a proven and respectable environmental management team, and has invested a lot of money in upgrades.\"\nWheelabrator's strong regional presence was also highlighted as a deciding factor in Macquarie's investment.\n\"We like the Northeast disposal market — it's on the cusp of change,\" Mitchener declared, noting the region's high population density, consistent and diverse waste generation, and relative economic stability. \"It's the most European market today. Prices have been rising for landfill disposal, but WTE plants are still receiving a lot of waste — and we don't think there's going to be any change in technology or regulation that's going to drive away a lot of the waste that's going to facilities we're investing in.\"\n\"We believe in WTE,\" he added. \"We don't care that some of these assets are 30 years old. We see a great future in this business.\"", "pred_label": "__label__POS", "pred_score_pos": 0.7236831188201904}
{"content": "Yes. You read it correctly –\nisocation. No typographical errors here. We know how the pandemic and the quarantine have sparked a phenomenal new wave of creativeness among people – learning new skills, discovering new hobbies, and – to the travel community – inventing new words.\nIsocation: an amalgamation of the words ‘isolation’ and ‘vacation’. The terminology refers to the anticipated travel trend following the cessation of quarantines and border closures wherein people will prefer to seclude themselves in luxury accommodations with exclusive in-house facilities and services. This is based on the certainty that people are eager to refill their need for leisurely travel, but planning for a future vacation is not without special attention to safety and health.\nHowever, though the word has a touch of novelty to it, such holiday experiences have long been enjoyed by elite travelers even before the pandemic. This is courtesy of luxury rental\nKeep reading this article on A Luxury Travel Blog.", "pred_label": "__label__POS", "pred_score_pos": 0.9981340765953064}
{"content": "Dissolving an LLC\nIf you choose to close a Colorado LLC (limited liability company), this will require you to complete several tasks. Dissolving the company is a key step that you absolutely cannot skip.\nAt formation, you registered your LLC with Colorado. Dissolution is formal process that officially ends your company's classification as business entity that is state registered. This process also ensures that claimants, including creditors, cannot reach the business.\nThe first step towards the voluntary dissolution of your Colorado LLC will be checking the operating agreement. An properly drafted operating agreement will almost always include a section dedicated to the dissolution process. Most of the time, these rules require LLC members to vote in favor of a resolution that will dissolve the company. There is likely a specific requirement of a minimum percentage of LLC members that must vote for the resolution. Ensure you follow the procedural requirements outlined in your dissolution rules. These may include providing members with advance notice of the meeting or setting the meeting and vote for a particular time.\nIf the operating agreement does not include a dissolution process or you do not have an operating agreement, the default rules in the Colorado LLC Act regarding voluntary dissolution of an LLC will apply. The Act lets you voluntarily dissolve the LLC if the members agrees.\nRegardless of the approach you take to dissolve the LLC, you must ensure you record all parts of the decision making process and draft a resolution of dissolution. This record will represent the dissolution meeting's official minutes.\nFiling the Dissolution Statement\nAfter voting to dissolve your LLC, you must file a dissolution statement with the Secretary of State. Under Colorado law, this statement of dissolution must include:\nYour LLC's name Your LLC's principal office address the state ID number of LLC\nYou do not need to craft the statement of dissolution from scratch or include your dissolution meeting's final minutes. The Secretary of State website has a form you will complete. Colorado requires you to file the statement online through the Secretary of State website and pay a $25 fee.\nThe online dissolution filing is typically processed immediately. You should note that following your LLC’s dissolution, others can legally use the business name.\nWinding Up Your Company\nAfter the dissolution with the Secretary of State is complete, the LLC still exists, but only to wind up the company's outstanding affairs. You can designate at least one manager or member of the LLC to handle the winding up process.\nThe Colorado LLC Act outlines several key tasks that are part of winding up. They include:\nSettling disputes Preserving the property or business of the LLC as a going concern over a reasonable period of time. Defending and prosecuting proceedings and actions against the company, including administrative, criminal, and civil. Collecting assets of the LLC. Disposing of properties of the LLC that will not be distributed in-kind to members. Distributing any remaining property of the LLC among members.\nIt is also crucial for your LLC to pay any outstanding taxes that are due. There is no requirement in Colorado for you to obtain tax clearance prior to dissolution and on your federal and state return you will simply mark the box labeled “final return” on the the appropriate form.\nSending Notice to Claimants and Creditors\nAnother key task involves providing notice to claimants and creditors. It is optional to give notice of the dissolution of the LLC to potential claimants and creditors, but it is wise to do so. Taking this step can reduce the potential liability of members, managers, and officers in the future. It may also provide additional safety when finalizing member distributions.\nBased on Colorado Law, you must give notice via a written document that is sent directly to any known claimants following dissolution. To count as proper notice, this written document must indicate that any claim filed against the LLC must take place by a stated deadline. If it does not occur by then, the action will be barred. The notice should also state that other limiting actions or statutes may bar these claims sooner than the stated deadline. You cannot list the deadline as any date sooner than two years following the date the notice is delivered.\nAlternatively, you can provide unknown claimants with notice via a newspaper ad. Check the specific requirements for using publication as notice as there are particular rules. Typically, claimants will have a time frame of five years following the publication date in which they can bring the claim.\nIf you decide to deliver notice to claimants that your LLC has dissolved, we strongly suggest you get assistance. Business attorneys will assist you with this.\nYou should also note that in cases where your LLC has registration in another state as well, you must file an additional form with that state.\nConclusion\nDissolving and winding up an LLC are just two of the many steps that may be involved in the process of closing down a business. You will likely need additional guidance to ensure you complete all steps that may be required for your business. If you would like to speak with a qualified and experienced attorney about your business, you can schedule a consultation through the contact link on our website.", "pred_label": "__label__POS", "pred_score_pos": 0.6536916494369507}
{"content": "Our Services Letter of Access management The European chemicals legislation REACH requires chemical substances that are placed on the EU market to be registered with the chemicals agency ECHA; and pursues the principle “one substance, one registration”.\nAll registrants of the same substance are obliged to the Joint Submission and must use the same data to avoid unnecessary animal testing.\nThe access right to the data for the participants in the Joint Submission is regulated via the so-called “Letter of Access” (LoA). By signing the Joint Submission Agreement, the co-registrant agrees to contribute to the total cost of registering a particular substance. These costs consist of the data, dossier and administrative costs and are reflected in the LoA fee. After payment of the LoA fee, the co-registrant receives the agreed files necessary for registration, the token allowing him to access the Joint Submission and the LoA document certifying the data access rights.\nFor more than ten years, we have been supporting consortia and lead registrants in the implementation of an efficient Letter of Access management system and are at your disposal as a competent partner\nwith the following services: Communication with potential and existing co-registrants Create and update Joint Submission Agreements Calculation of LoA fees Invoicing Issuing of LoA documents and sending the files required for registration to co-registrants (basic IUCLID, CSR, and token) Documentation and required data updates Management of LoA fees on trustee accounts Recalculation and processing of reimbursements or additional charges", "pred_label": "__label__POS", "pred_score_pos": 0.7117156386375427}
{"content": "Abstract\nDuring the intraerythrocytic stage of infection, the malaria parasite Plasmodium falciparum digests most of the host cell hemoglobin. Hemoglobin degradation occurs in the acidic digestive vacuole and is essential for the survival of the parasite. Two aspartic proteases, plasmepsins I and II, have been isolated from the vacuole and shown to make the initial cleavages in the hemoglobin molecule. We have studied the biosynthesis of these two enzymes. Plasmepsin I is synthesized and processed to the mature form soon after the parasite invades the red blood cell, while plasmepsin II synthesis is delayed until later in development. Otherwise, biosynthesis of the plasmepsins is identical. The proplasmepsins are type II integral membrane proteins that are transported through the secretory pathway before cleavage to the soluble form. They are not glycosylated in vivo, despite the presence of several potential glycosylation sites. Proplasmepsin maturation appears to require acidic conditions and is reversibly inhibited by the tripeptide aldehydes N- acetyl-L-leucyl-L-leucyl-nor-leucinal and N-acetyl-L-leucyl-L-leucyl- methional. These compounds are known to inhibit cysteine proteases and the chymotryptic activity of proteasomes but not aspartic proteases. However, proplasmepsin processing is not blocked by other cysteine protease inhibitors, nor by the proteasome inhibitor lactacystin. Processing is also not blocked by aspartic protease inhibitors. This inhibitor profile suggests that unlike most other aspartic proteases, proplasmepsin maturation may not be autocatalytic in vivo, but instead could require the action of an unusual processing enzyme. Compounds that block processing are expected to be potent antimalarials.\nASJC Scopus subject areas Biochemistry Molecular Biology Cell Biology", "pred_label": "__label__POS", "pred_score_pos": 0.5532081723213196}
{"content": "Vitamin D3 is produced by the photolytic action of ultraviolet radiation on the skin. Despite the fact that any organism can produce the quantity of Vitamin D3 it requires, modern lifestyle and insufficient exposure to solar radiation results in Vitamin D3 deficiency, the intake of which is mandatorily through nutrition, due to its very important role in maintaining good health.\nVitamin D3 has a significant role in maintaining calcium and phosphate homeostasis and consequently maintaining healthy bones and teeth. Additionally, Vitamin D3 participates in tissue metabolism and its presence in sufficient quantities is substantial for the differentiation of cells and the preservation of membrane functionality , as well as for the function of various organs such as the skin, the muscles, the pancreas, the nerves, the parathyroid gland and the immune system.\nTablets: 1200IU/tab, 2000IU/tab, 4000IU/tab", "pred_label": "__label__POS", "pred_score_pos": 0.9894044995307922}
{"content": "Coles and Woolworths in Australia have decided to reinstate buying limits on toilet roll and paper towels after a surge in demand.\nReacting quickly is vital to manage stock flow\nColes was the first of the two major retailers to lift all of its buying restrictions a few weeks ago, followed by Woolworths shortly afterwards. However, the recent demand has led Coles to restrict buying to one pack of each item per customer and Woolworths limiting it to two of each item. Woolworths Supermarkets managing director, Claire Peters, explained that although demand isn't as high as before, or the same nationwide, Woolworths was moving quickly to ensure that stock remained flowing.\nLimits could come and go for some time\nThe last thing that major retailers globally want is to see a repeatition of panic-buying that occured at the start of the pandemic. Retailers and suppliers continue to work increasibly hard to ensure that shelves remain stocked and managing purchasing limited could be something that we continue to see for sometime.\nBefore the nationwide announcement, Woolworths had already reinstated a new limit of two items per customer on toilet paper, hand sanitiser, paper towels, flour, sugar, pasta, mince, long-life milk, eggs and rice in the state of Victoria, where there has been a resurgence in panic-buying. However, even if there are peaks in buying across certain states, retailers may still impose nationwide limits, particularly on high demand items, to ensure that stock is fairly distributed.", "pred_label": "__label__POS", "pred_score_pos": 0.882574200630188}
{"content": "India: 'Small Entity' criteria for classification under various IP Enactments broadened Various IP enactments, including the Patents Act, Trade Marks Act and Designs Act, provide for a discounted official fee for ‘small entities’ that are defined as entities meeting the criteria of 'medium enterprise' under the Micro Small and Medium Enterprises Development Act, 2006 (MSME Act). Further benefits for ‘small entities’ include expedited examination of their patent applications which can be requested under the provisions of the Indian Patents Act. The applicable criteria for evaluation of a 'small entity' will be revised with effect from July 1, 2020. As per the revision, an enterprise that meets the following criteria (investment limit and turnover limit) may avail the fee benefits of ’small entity’ under the Indian IP laws: After revision:\nBefore the revision, the criteria for classification as a ‘small entity’ was the investment limit of an enterprise. To be categorized as a “small entity”, the investment limits were as follows: Before revision:", "pred_label": "__label__POS", "pred_score_pos": 0.5786833167076111}
{"content": "The District of Columbia is becoming increasingly more segregated by race and income. As outlined in the Urban Institute report The Color of Wealth in the Nation’s Capital, this segregation is built on racist public and private practices, and has amplified disparities and inequities in health, education, work opportunities, with effects that continue today.", "pred_label": "__label__POS", "pred_score_pos": 0.7373129725456238}
{"content": "by Margaret Haylock Capon\nRecently, I received a “Remember When” e-mail from an old school friend, who was one of my classmates at Picton’s Mary Street School, in the 1950’s. It contained illustrations of approximately 30 items described as blasts from the past. Among them were ice cube trays with levers, Studebaker cars, juke boxes, and candy cigarettes. When I had scrolled to the bottom of these images, I discovered a line that read “if you can remember all of these, then you are old.” Reluctantly, I admitted that I could clearly remember everything, with the exception of someone called Marlin Perkins and a beverage identified as Falstaff beer.\nWhen I replied to my former classmate’s e-mail, I observed that we were, indeed, vintage. Then, I asked if he could remember penny candy. My question prompted both of us to reminisce about Scott’s Groceteria, a small corner store near the present location of Cope-Barrett. My friend confided that he often stopped there on his way to school. I, too, remembered counting out my pennies to buy blackballs, caramels, and sourballs, all at three for a cent. We also recalled wax lips, licorice pipes, and similar confections that tickled the tongues of the younger set.\nWhile sharing our memories of penny candy, I confided that my experience with these sweets did not end in childhood. When I was 17 years old, I took a summer job at East End Grocery, a corner store at Main and Division Streets. The proprietor, Johnny Kavanaugh, was one of the few local grocers who still sold penny sweets.\nThe candy counter was located behind the counter, immediately to the left of the cash register. Pasteboard boxes were filled with taste treats including Jujubes, chocolate and butterscotch caramels, blackballs, sourballs, candy cherries, licorice babies, and candy wafers in pastel colours, which were imprinted with messages such as ‘I Love You’. Beside the candy counter was a stack of small brown paper bags waiting to be filled.\nInitially, I was intrigued by the penny candy display, for it brought back fond memories of my childhood. However, I quickly came to regard these sweets as an irritating carry-over from another era. When neighbourhood children came into the story, many of them brought pop bottles to be redeemed for penny candy. When I had paid them their deposit fees, they would then gaze intently at the selection of penny candy, before slowly deciding on their purchases. Often, it took five minutes or more, for a youngster to fill a small paper sack with candy. As my small customers stood on tip-toe to peer over the counter, often a line-up of impatient grown-ups with grocery items formed behind them.\nAfter working at the store, for a short time, I decided that a candy express lane was urgently needed. I began by trying to hurry the children along as they made their choices. I would suggest that licorice whips were an excellent value or mention that blackballs would outlast caramels, but as I began to reach for these treats, the children invariably would counter my recommendations with requests for other confections. It was not unusual for them to change their minds three or four times. Drastic action obviously was needed.\nWith Johnny’s consent, I introduced the grab bag. I made up these bags of penny candy in three sizes priced at a nickel, a dime, and a quarter (for the big spenders). I, then, twisted the tops of the paper sacks tightly and placed them on the counter where the penny candy had previously been displayed. The children’s initial reaction was one of disbelief. I was immediately asked where the licorice babies had gone and small customers began to argue that they were not about to spend a nickel for a bag of treats that might not contain any blackballs. I stood firm and told them that they would have to pay their money and take their chances. To mollify them, I assured them that I had carefully selected a variety of candies and they could be sure that at least one of their favourites would be found in every paper sack.\nAfter a few days, it became obvious that my new marketing scheme was a failure. The sale of penny candy plummeted. No longer able to savour the delightful experience of choosing, our little customers had decided to boycott the candy counter. By mutual agreement, Johnny and I made a return to the old system. All of the grab bags were emptied and free choice was restored. Throughout my two-year career as a grocery store clerk, I continued to tap my foot impatiently, as neighbourhood youngsters, each day, began the painstaking selection of their candy.\nIn later years, I came to realize that, for my small customers, selecting the right candy was almost as much fun as eating it. With only a few cents in their pockets, the world was at their feet. They possessed that heady sense of power that comes with the freedom to choose. Their mothers might have told them what to wear that day and their teachers had decided what they would learn, but when it came to penny candy they were free to buy whatever they liked.\nToday, I wonder if the children I once served with such impatience will one day recall penny candy as a special part of their childhood. If they do, I hope they will have no recollection of East End Grocery’s cranky clerk. Now that the internet has proclaimed me officially old, I have realized the error of my youthful ways.\nFiled Under: Margaret Haylock-Capon About the Author: Maggie Haylock is a freelance writer and former newspaper reporter who has co-authored several books with her husband, Alan Capon.", "pred_label": "__label__POS", "pred_score_pos": 0.6843175888061523}
{"content": "There is no doubt that complex simulations are an efficient, realistic, and engaging way to measure a diverse set of competencies. To that end, HumRRO\ndevelops fully customized, client-owned, high fidelity simulations that take advantage of branching and multi-level animation to place the test taker in realistic situations. The simulations can be administered online and on demand. The use of branching technology allows the tool to track and score responses at several points during the assessment process. Our content oriented development approach ensures a high degree of job-relatedness and face validity. Additionally, we have conducted several criterion-related validity studies which have shown strong relationships between these rich-media assessments and job performance. The simulations produce valid and reliable scores while providing an engaging experience that today’s users expect and demand. When used for development, participants also receive competency-based feedback to stimulate self-reflection and facilitate discussions with peers, mentors, or supervisors. Because our assessments are fully customized, they reflect each client organization’s culture, values, and policies.", "pred_label": "__label__POS", "pred_score_pos": 0.6673399209976196}
{"content": "India has one of the lowest motorization rates in the world, but is set to take off in a similar trajectory as China and the U.S. In India, air pollution has reached crisis levels. Motor vehicles are estimated to contribute 20 to 40 percent of the air pollution in major cities, such as Ahmedabad and Delhi. In recent years, the Indian government has made serious commitments to tackle the air quality and mitigate emissions along with initial electric mobility programs and policies.\nAround the world, leading countries have announced ambitious electric vehicle (EV) goals and proposed plans to end gasoline and diesel sales. India has introduced programs to advance electric mobility through the Faster Adoption and Manufacturing of Hybrid and EV (FAME) scheme and charging infrastructure programs while several states in India have announced EV policies. A widespread, accessible public charging infrastructure network is needed to support a robust EV market – as evidenced by experiences in China, the United States, and around the world. In India, EV sales would need to reach 30% for private cars, 70% for commercial cars (i.e. delivery vehicles, fleets, and taxis) 40% for buses and 80% for two and three-wheelers by 2030 to achieve the government's electric mobility goals, according to analysis by the Indian government.\nUnder the second phased of the FAME scheme (2019), India is set to bring nearly 2,600 electric vehicle (EV) charging stations across the country starting in 2020, to enable growth in the nascent EV markets. However, to achieve India’s EV goals, an aggressive scale-up will be needed in the deployment of charging infrastructure. To support the scale-up, it will be key to understand the challenges faced by the EV charging infrastructure market and strategies government agencies, utilities, charging service providers, and automakers are deploying to overcome these challenges.\nGiven the close connections of the transport sector on clean air, health, jobs, and energy security, the case for an action on electric mobility is more compelling than ever in India. NRDC and partners, through their work at the national- and state-level, focus on advancing electric mobility so that India can march ahead to meet its transport electrification, air quality and climate change goals.", "pred_label": "__label__POS", "pred_score_pos": 0.8852682709693909}
{"content": "The private equity real estate industry has taken its first steps towards standardized reporting with the publication of a digital dictionary.\nThe Global Definitions Database includes a common glossary of non-listed real estate terms, which have been either agreed to globally, or are region-specific. New terms are expected to be added to the online publication in the future.\nThe GDD should increase alignment among private real estate fund managers, streamline processes and create more consistency in reporting, according to John Ravoisin, member of the Global Definitions Tax Force.\nThe database was compiled by industry bodies including the Asian and European Associations for Investors in Non-listed Real Estate Vehicles, the Pension Real Estate Association and the National Council of Real Estate Investment Fiduciaries.\nIt is part of a wider initiative, spearheaded by the organizations, to create a set of global reporting standards and guidelines which aims to address the disparities in global real estate operations. There are standardized due diligence questionnaires in Europe and Asia that are not used in the US, while the US’s focus on risk management is less emphasized than in other regions, for example.\nThe consortium will now work on developing a standardized fees and expenses metric and an accompanying investor reporting template.", "pred_label": "__label__POS", "pred_score_pos": 0.8968683481216431}
{"content": "The title of this post may puzzle you if you haven't spent a lot of time in Florida. Everything here is an extreme. I needed a couple of yearsbefore I realized the extent of Florida's extremes.\nIf it looks like a nice, sunshiny day, odds are it's 99 F (37 C). After a while here, you start thinking that 86 F (30 C) is nice and cool.\nWhen I grew up, my mom always emphasized the importance of being outside in the sun and enjoying sunny days. In Florida that way of thinking will get you a heatstroke and possibly skin cancer.\nIf it's cold, it's probably not all that cold on the thermometer, but the combination of high humidity and being used to 99F makes 45 feel like the coldest it has been anywhere. Ever.\nIf it rains, you think investing in a car might have been a mistake - clearly you should have bought a boat. Or, built an ark. My current workplace would be understanding if weather prevented me from appearing on time, but I have had an employer who said, \"It's just a tornado.\"\nA windy day somewhere else might be an inconvenience. A windy day in Florida will blow the roof off your house.\nPlants that barely survive potted in a greenhouse in other places become trees in Florida.\nBig trees.\nBugs in other places are small and can be annoying. Bugs in Florida grow to the size of small birds. Or, there's a billion of them. Not joking. A billion.\nSince I'm afraid of bugs I'll do everyone a favor and not include a picture of\nthat.\nLove bug season sounds cute. It is not.\nSnowbird season also sounds cute. It is not. It's hard to find crowds like tourist season in Florida.\nDo you have extremes where you live? What's the worst?", "pred_label": "__label__POS", "pred_score_pos": 0.8298856616020203}
{"content": "Strathcona County RCMP Remind Residents To Lock Their Vehicles Strathcona County RCMP remind residents to lock their vehicles\nStrathcona County, Alta. – Strathcona County RCMP is urging residents to take steps to prevent vehicle thefts and theft from vehicles. Most vehicle crime is opportunistic and by following some straightforward advice, and working together, we can ensure that this type of crime is reduced in our community.\nThefts from vehicles are more likely to occur in areas that contain many vehicles and minimal pedestrian traffic. Theft of vehicles also increases in areas with less visibility such as rural properties. Regardless of the location, any area where a vehicle is left running and unattended, unlocked, or with valuables in plain view, the risk is increased.\nSteps for protecting your vehicle can be as simple as closing the windows and removing the keys when you leave. Here are more tips for preventing thefts:\nLock the doors. Remove valuables from vehicle including purses, shopping bags, change, electronics and sunglasses. Remove garage door opener. Park your vehicle in sight or in a well-lit area. Use a steering wheel lock. Lock your garage. Disable power to the garage door if you’re leaving for an extended period of time\nIf you see something suspicious, report it the Strathcona County RCMP at 780-467-7741. If you see a crime in progress, call 911. If you wish to remain anonymous, you can contact Crime Stoppers at 1-800-222-8477 (TIPS), online at www.P3Tips.com or by using the “P3 Tips” app available through the Apple App or Google Play Store.", "pred_label": "__label__POS", "pred_score_pos": 0.6933612823486328}
{"content": "Congenital syphilis is a severe, disabling, and often life-threatening infection seen in infants. A pregnant mother who has syphilis can spread the disease through the placenta to the unborn infant.\nCongenital syphilis is caused by the bacterium\nTreponema pallidum, which is passed from mother to child during fetal development or at birth. Nearly half of all children infected with syphilis while they are in the womb die shortly before or after birth.\nDespite the fact that this disease can be cured with antibiotics if caught early, rising rates of syphilis among pregnant women in the United States have increased the number of infants born with congenital syphilis.\nSymptoms in newborns may include:\nSymptoms in older infants and young children may include:\nIf the disorder is suspected at the time of birth, the placenta will be examined for signs of syphilis. A physical examination of the infant may show signs of liver and spleen swelling and bone inflammation.\nA routine blood test for syphilis is done during pregnancy. The mother may receive the following blood tests:\nAn infant or child may have the following tests:\nPenicillin is used to treat all forms of syphilis.\nMany infants who were infected early in the pregnancy are stillborn. Treatment of the expectant mother lowers the risk of congenital syphilis in the infant. Babies who become infected when passing through the birth canal have a better outlook.\nCall your health care provider if your baby has signs or symptoms of this condition.\nIf you think that you may have syphilis and are pregnant (or anticipate becoming pregnant), call your health care provider immediately.\nSafer sexual practices may help prevent syphilis. If you suspect you have a sexually transmitted disease such as syphilis, seek medical attention immediately to avoid complications like infecting your baby during pregnancy or birth.\nPrenatal care is very important. A routine blood test for syphilis is done during pregnancy. This identifies infected mothers and allows them to be treated to reduce the risks to the infant and themselves. Infants born to infected mothers who received proper penicillin treatment during pregnancy are at minimal risk for congenital syphilis.\nCongenital lues; Fetal syphilis", "pred_label": "__label__POS", "pred_score_pos": 0.627682089805603}
{"content": "Coronavirus Effect on Media Houses Goals To outline some of the media houses that are addressing the coronavirus crisis. Early Findings Theaters\nNATO\nIn the first week of March 2020, the box office has experienced a 60% decline from 2019, due to the coronavirus crisis. The National Association of Theater Owners (NATO) has taken the initiative to request the federal government for aid to support over 100,000 staff members in movie theaters during the coronavirus crisis. Streaming Services Netflix\nStreaming services such as Netflix are likely to experience an overwhelming subscription due to social distancing. Since the start of the year to mid-March, Netflix’s shares have gone up by 12.5%.\nInvestors are favoring Netflix as it is relatively virus-proof due to the zero exposure to epidemic-related environments. Thus, the company stands to benefit more should the epidemic intensify and people avoid public places such as movie theatres.\nDisney +\nEven though Disney’s media empire has been rendered empty due to the coronavirus outbreak, with its theme parks closed, Disney is making the best out of its streaming services, such as Disney +.\nRecently, Disney announced that it would make Frozen 2 available on Disney + by March 15, to help families contain anxiety during the coronavirus crisis. This has been prompted by the successful theatrical release, which has raked in $1.4 billion worldwide.\nProposed next steps:\nYou need to be the project owner to select a next step.", "pred_label": "__label__POS", "pred_score_pos": 0.8459054231643677}
{"content": "You’ve cleaned your entire house, mopping and sweeping the floors, cleaning up crumbs and vacuuming, but you keep seeing roaches! Unfortunately, even in a clean house roaches can find their way inside. Cockroaches seek out three things: water, food, and shelter. While you might think you’ve taken all the necessary precautions, there could be some elements you’re missing that can attract roaches to your home.\nRoaches are thigmotactic, meaning they want to feel contact on all sides of their bodies. Because of this, they are commonly found nesting in places such as wall cracks, under sinks, in drains, and even water heaters. Every home has these features so despite your best cleaning efforts, these pests can still find a way in through small gaps or doors to reach these locations.\nEven the cleanest of homes can still have the occasional leaky pipe or faucet. Roaches need moisture to survive and are constantly searching for it. Areas where moisture has accumulated is an attractant to roaches. Refrigerators and air conditioning units are two common places that these pests infest. Cockroaches enjoy dark areas equally as much as they do water. You can traditionally find these pests in basements near appliances that use water, too.\nBesides what brings them inside your home, roaches are also attracted to what’s outside. Standing water in places like gutters, flowerpots, or birdbaths can also attract these pests to your property. Trash and recycling bins also provide a great food source for roaches, as they typically will eat garbage.\nSeal any cracks and gaps that are leading into your home Repair any water leaks throughout your house Sweep daily and vacuum your house weekly Keep your garbage and recycle cans sealed\nTired of dealing with roaches yourself? Consider calling a professional pest control company who can inspect your home, identify where these pests are getting in from, and provide you with a customized plan to treat them.", "pred_label": "__label__POS", "pred_score_pos": 0.5897846221923828}
{"content": "19 Jan True happiness cannot be bought\nAs holiday sales stretch earlier and earlier into the year, many have wondered what effects America’s increase in materialism has been having on our nation’s children.\nIn a study recently conducted by Lan Nguyen Chaplin, a professor of marketing at the University, researchers asked children to rate the value they placed on materialistic objects such as ‘stuffed animals,” “money” and ‘sports equipment,” and compared these responses with how the children rated non-materialistic sentiments like “being with friends,” “being good at sports” and “helping others.” Researchers also evaluated the self-esteem of the children and compared the results.\nA report recently released by Chaplin documenting the results of her study reveals that self-esteem is a key factor in a child’s level of materialism. Simply put, children who have low self-esteem tend to value material possessions more than children who don’t. While this study focused on youth, its findings speak to a greater reality that all of us living in a materialistic society, regardless of age, must face.\nTo what extent does your happiness depend on ‘stuff”? To what extent do you associate happiness with material possessions? Depending on your answers to these questions, how “real” is your happiness?", "pred_label": "__label__POS", "pred_score_pos": 0.7912476062774658}
{"content": "Though surrogacy law can vary from one state to another in the U.S., there are countries where gestational surrogacy, or even surrogacy generally, is entirely prohibited. When surrogacy isn’t allowed, it can leave those couples and individuals who are relying on this form of third-party reproduction to build their families in the lurch. In order to have a child in the manner they desire, international couples will need to travel to countries that are surrogacy friendly, often the United States.\nInternational intended parents will need to work with a gestational surrogate who resides in a state where surrogacy laws do not prohibit an agreement from taking place. Surrogacy friendly states include California, Colorado, Connecticut, Delaware, Georgia, Illinois, Indiana, Iowa, Kentucky, Maine, Maryland, Massachusetts, Minnesota, Missouri, Nevada, New Jersey, New Mexico, North Carolina, Ohio, Oregon, Pennsylvania, Rhode Island, South Carolina, South Dakota, Tennessee, Texas, Utah, Vermont, Washington, Washington DC, West Virginia, and Wisconsin.\nCountries where surrogacy is not currently allowed or faces restrictions include France, Germany, Spain, Italy, Portugal, Russia, England (all of the United Kingdom), and Denmark.\nTraveling for surrogacy\nInternational intended parents are encouraged to choose a third-party reproductive agency that has experience working with couples and individuals traveling for surrogacy. The surrogacy process is complex for those who already reside in the U.S., and a travel schedule and possible language barrier will increase this complexity. Fortunately, there are advantages to choosing a U.S.-based agency like Fertility SOURCE Companies.\nRegulated medical care provided Very strict egg donation and gestational surrogacy screening High IVF success rates Favorable / friendly fertility laws (can depend on the individual state) Multiple cross-country locations for intended parents to choose to travel to (fertility friendly states from coast to coast) Your case manager\nA core benefit to choosing an agency like Fertility SOURCE Companies is working with an assigned Case Manager. Our Case Managers have worked with countless international growing families and can assist with everything from travel arrangements to coordination / selection of a fertility clinic, discussion / review of fees, medical procedures, legal issues, and more. Many intended parents express considerable relief at being able to rely on a Case Manager who is specifically assigned to their third-party reproduction journey.\nIf you have questions about international surrogacy, working with an agency, or a Case Manager, please contact Fertility SOURCE Companies today.", "pred_label": "__label__POS", "pred_score_pos": 0.6155987977981567}
{"content": "ISBN : 9780195529081\nWhere issues and crisis management intersect and converge with risk and reputation is one of the most dynamic and challenging areas of management and professional communication. Moreover, the new Process Approach to issue and crisis management reveals that these disciplines are not separate activities but form part of a continuum of management responsibilities which comprise a comprehensive response to events or developments which threaten organisational reputation or success Issues and Crisis Management: Exploring Issues, Crises, Risk and Reputation introduces and explores each element, while at the same time emphasising the relationship between them all.\n1. Setting the framework\n2. Issue Management - Development and Tools 3. Issue Management - Identification and Prioritisation 4. Issue Management - Planning 5. Issue Management - Activism 6. Crisis Management - Readiness and response 7. Crisis Management - Planning 8. Crisis Management - International 9. Crisis Management - Disasters 10. Risk Management - Perception, Hazard and Outrage 11. Risk Management - Reputation 12. Leadership and the future", "pred_label": "__label__POS", "pred_score_pos": 0.9663245677947998}
{"content": "The Health and Safety Executive (HSE) has warned against the use of KN95 facemasks as Personal Protective Equipment (PPE). A safety alert has been issued, urging all employers and suppliers not to purchase or use KN95 facemasks as PPE.\nThe alert stated that \"KN95 is a performance rating that is broadly equivalent to the EU standard for FFP2 facemasks. Products manufactured to KN95 requirements rely on a self-declaration of compliance by the manufacturer. There is no independent certification or assurance of their quality.\nThis respirator has been identified as suspect by HSE experts and locally arranged testing has confirmed they would not meet requirements, including to protect against the ongoing coronavirus pandemic. About 90% of the PPE concerns and queries currently being received by HSE involve KN95 masks which are often accompanied by fake or fraudulent paperwork.\"\nThe required action within the alert is that \"masks that are not CE marked and cannot be shown to be compliant must be removed from supply immediately.\"\nWhere masks are CE marked, \"suppliers must be able to demonstrate how they know the documentation and CE marking is genuine, supported by Notified Body documentation showing compliance with the essential health and safety requirements as required by the Personal Protective Equipment Regulations (EU) 2016/425.\"", "pred_label": "__label__POS", "pred_score_pos": 0.9904387593269348}
{"content": "Abstract\nWind power in the NE (Northeast) region of Brazil is currently undergoing rapid development and installed capacity is expected to exceed 16,000 MW by 2020. This study examines the feasibility of integrating large scale wind power into an electricity grid (the Brazilian NE subsystem) which has a high proportion of existing hydroelectricity. By extrapolating existing wind power generation data, the maximum achievable wind power penetration (without exports to other Brazilian regions) and corresponding surplus energy is determined for the NE subsystem. The viable maximum penetration of wind energy generation in the NE subsystem was estimated to be 65% of the average annual electricity demand assuming that existing hydroelectric and gas generators have 100% scheduling flexibility. These results are compared to the actual gross penetration of wind power forecast to reach 55% in the NE subsystem by 2020. The overall LCOE (levelised cost of electricity) is calculated for various scenarios where wind power replaces all fossil fuel generators in NE subsystem. It was concluded that by 2020, wind power could feasibly reduce the overall LCOE by approximately 46-52% and reduce CO\n2eq emissions by 34 million tonnes per year compared to a power system with no new renewable generation. Keywords Hydroelectricity Integration LCOE (levelised cost of electricity) Renewable energy Wind power", "pred_label": "__label__POS", "pred_score_pos": 0.6738898754119873}
{"content": "Cistus Ladanifer is an ancient healing herb that has been used for centuries to treat a variety of conditions such as respiratory problems, painful joints, arthritis, hormonal imbalance and anxiety. It is very high in antioxidants and gives a great boost to your immune system.\nHowever, this powerful plant is also known for its anti-ageing properties; consequently, by drinking two cups a day you will not only feel revitalised, your complexion will also appear clearer, brighter and develop a radiant glow.\nYou only need half a teaspoon in a small teapot, let this steep for a couple of minutes and then drink (sweeten with honey if desired.)", "pred_label": "__label__POS", "pred_score_pos": 0.5039591789245605}
{"content": "Abstract\nThis study assessed psychological disorders in 50 patients with chronic temporomandibular disorders and 51 patients with acute TMD. The results revealed a significant psychological comorbidity in both groups of patients. Both groups had high rates of psychopathology that exceeded the base rates of the general population. Such findings are in keeping with an integrated biopsychosocial model of TMD, and have significant implications for treatment of these patients.\nASJC Scopus subject areas Dentistry(all)", "pred_label": "__label__POS", "pred_score_pos": 0.8583539128303528}
{"content": "Abstract\nDespite National Institutes of Health recommendations to administer antenatal steroids as a single course to women threatening preterm delivery, repeated treatments are often given. We investigated effects of repeated dexamethasone (DM) administered to the ewe on small maternal and foetal placental arteries. We hypothesized that DM would increase responsiveness to endothelin-1 (ET-1) and norepinephrine (NE) and that foetal arteries would react differently to ET-1 and NE compared to maternal arteries. Ewes received three treatments beginning at 103, 110, and 117 days of gestation (dGA). Each treatment consisted of four IM injections of 2 mg DM or saline at 12-h intervals. At 119 dGA, in vitro functional studies were performed using Mulvany wire myography and endothelin receptor (ETR) expression was quantified using real-time RTPCR and receptor ligand autoradiography. Foetal placental arteries demonstrated greater maximal contractility to ET-1 and lesser maximal contractility to NE compared to maternal arteries. DM increased the maximal contraction elicited by ET-1 and NE in foetal but not maternal placental arteries. DM also increased the abundance of type-A ETR but not type-B ETR mRNA in foetal but not maternal placental arteries. However, within the whole placentome, DM increased the abundance of type-B ETR and decreased type-A ETR mRNA, which was confirmed by similar changes in ETR binding specifically within the labyrinth region. In summary, repeated DM treatment results in agonist and vascular bed specific responses within the placenta.\nASJC Scopus subject areas Reproductive Medicine Obstetrics and Gynecology Developmental Biology", "pred_label": "__label__POS", "pred_score_pos": 0.5246115326881409}
{"content": "While many may not look at burn injuries as being as catastrophic as a brain injury or spinal cord injury, it’s important to recognize just how damaging they can be. You can suffer a burn injury in many different situations, with many of them resulting from negligence.\nRecognizing the different types of burn injuries and how severe the damages are can be important to pursuing legal action.\nTypes of Burn Injuries\nWhen you need to file a lawsuit against someone for a burn injury you may sustain, recognizing the potential cause can help you hold a specific person responsible. The cause of the burn often determines the potential type of a burn injury, which can include:\nThermal burnsresulting from contact with flames or hot liquids or objects Chemical burnsresulting from contact with bleach, acid, chlorine, ammonia, and more Electrical burnsresulting from contact with open currents Friction burnsresulting from repeated contact between your skin and another surface Radiation burnsresulting from prolonged exposure to radiation Degrees of Burn Injuries\nBurn injuries are categorized based on their severity and the symptoms you display.\nFirst-degree burns:These burn injuries are the least severe, often resulting in just damage to the epidermis (first layer of skin). This is commonly something like a sunburn. Second-degree burns:These can result in damage to your epidermis and dermis, often resulting in severe pain. A skin graft may be needed for these types of burns. Third-degree burns:The more severe burns are third-degree burns and can result in damage to sweat glands and tissue underneath the layers of skin.\nThe most severe burns can cause nerve damage, making the affected area numb of sensation or pain.\nAt Crane Flores, LLP, we commit ourselves to helping you through the most challenging matters. Let our team help you pursue the outcome you need and deserve. Our personal injury attorneys represent clients from Ventura, Oxnard, and Santa Barbara.", "pred_label": "__label__POS", "pred_score_pos": 0.5253919363021851}
{"content": "Nigeria’s leading Engineering, Procurement, Construction and Commissioning (EPCC) Services Company, Nestoil Limited, has won the ‘Best Company’ in Infrastructural Development’ at the the 10th edition of the SERAs (Social Enterprise Report Awards) ceremony held at the Muson Centre in Lagos Nigeria on Friday November 11, 2016.\nThe SERAS CSR Awards are Nigeria’s first and most prestigious Corporate Social Responsibility (CSR) Awards, featuring other African participants.\nNestoil emerged winner in ‘Best Company’ in Infrastructural Development’ category, which had other notable organisations and multinationals such as Exxon Mobil, GT Bank, Shell Petroleum Development Company (SPDC), OANDO Foundation, MTN Nigeria and Lafarge,as an acknowledgment of its social connectedness and contributions to societal development.\n“We are not a quoted company, but we are a business with a conscience. We will continue to conduct our operations and selves in a manner that will promote social good and well-being of mankind. As an organization, Nestoil is committed to conducting its operations in a socially responsible manner, and we take awards such as this as reminders to organisations, business leaders and managers of their creeds sustainability”, ‘Segun Fafore, Head, Corporate Communications, who received the award for the company.\nAs an organisation that operates in the oil and gas sector, Nestoil is fully aware of its obligations to nature, humanity and the society at large. The company, through its Corporate Social Responsibility arm, the Obi jackson Foundation, has evolved and implemented progarmmes that support the attainment of the eight Millennium Development Goals (MDGs).\nAcknowledged for its industry leadership through execution of technically complex projects which have enhanced quality of life in Nigeria and contributed to the operational efficiency of its clients, Nestoil is consistently seeking innovative avenues for striking a balance between its economic activities and environmental sustainability.\nConsequently, the company has not only integrated sustainability into its operations, but also identified key focus areas of social intervention. These areas are Education, Health& Safety,Economic empowerment, Community Investment and Development, Sports Gender Equality &Women Empowerment and Environment.", "pred_label": "__label__POS", "pred_score_pos": 0.9243460297584534}
{"content": "When the symptoms of the cancer reduce or disappear. A partial remission is when there has been a significant improvement in the cancer. A complete remission is when there is no evidence of active cancer….\nSearch: remission\nTreatment given to cure the cancer, such as chemotherapy or radiation therapy. This does not include long-term treatment such as hormone medication, which may be taken for several years to maintain remission.", "pred_label": "__label__POS", "pred_score_pos": 0.9997994303703308}
{"content": "Degree\nDoctor of Philosophy (PhD)\nDepartment\nEnglish\nDocument Type\nDissertation\nAbstract\nWhile research on motivation in second language acquisition is copious and the interest in undocumented youth within the education field is growing, there is a need to closely examine the intersection of being both undocumented and an English Learner (EL) and how this intersection often limits ELs, especially those in underserved schools. Using ethnographic methods, this dissertation documents the educational experiences of thirty-one Spanish-speaking ELs in a predominately of color, urban, working-class high school in the southeastern United States. EL participants were ages fourteen through twenty with varying non-citizen immigrant statuses. Semi-structured interviews and field notes were collected during the 2017-2018 school year, with follow-up interviews conducted eight months after nine participants had left high school. This study uses a desire-centered theoretical approach (Tuck, 2009), which highlights the complexities and contradictions of lived experience instead of focusing exclusively on the damage and trauma that often frames marginalized voices as depleted and helpless. The study categorized the desires that emerged into “intertwined” and “vital” desires. Intertwined desires include undocumented ELs yearning to learn English and graduate high school to gain social capital in the United States and as a contingency plan in case of deportation to their native countries. Additionally, undocumented ELs desire more inclusive school spaces where they are not alienated because of language and nationality differences. As a result of these gaps in academic and emotional support, ELs fostered solidarity and peer mentoring. Vital desires include safety, connection, and guidance. Since limited English abilities and undocumented status are often barriers to college and career opportunities, undocumented ELs desire guidance as they make decisions about life after high school and stronger connections with peers and family as they contend with the uncertainty of a non-legal status. The study recommends investing in healing-centered, culturally-sustaining curriculums and highly-trained educators among other interventions for policy and practice.\nDate\n5-15-2020\nRecommended Citation\nTorres, Alejandra Sofia, \"Documenting Desire: Addressing the Educational Needs of Undocumented English Learners\" (2020).\nLSU Doctoral Dissertations. 5256. https://digitalcommons.lsu.edu/gradschool_dissertations/5256 Committee Chair\nWeinstein, Susan", "pred_label": "__label__POS", "pred_score_pos": 0.5057435035705566}
{"content": "Educators Anti-bias Education\nWe understand the ways that media influence young people’s understanding of their world and are committed to questioning certain language, roles, stereotypes, and attitudes.\nLesson plans are the cornerstone of Journeys’ work, reinforcing academic standards while teaching young viewers how to watch a film and challenging them to examine how their own experiences influence their perceptions of others. We provide prompts within the lesson plans to confront bias and typecasting that are perpetuated by media makers, adding to society’s adoption of these harmful attitudes. These prompts are excellent tools for today’s educators who say that they often feel inadequate to teach subjects in a multi-cultural context.\nWe believe many films can be transformative educational resources to facilitate community dialogue, inspire proactive learning for youth, parents, and educators who desire to advocate for certain causes. Educators crave resources to address the inequities present in our society, especially those that affect inequalities in education.\nOur Methodology Following the lead of educators Grant Wiggins and Jay McTighe, we use a “backward-design” process that follows several steps: Identify main ideas or Enduring Understandings Establish Essential Questions Determine key knowledge and skills to be taught Determine the evidence of learning students should present at the end of lesson Provide background notes to teachers and assessment tools Provide instructions for the “how-what-when” Provide downloadable interactive materials Curriculum Lesson and Engagement Plans Include: Pre-film viewing preparation and subsequent lessons Recommendations for creating the best setting for film viewing Recommendations for special reading needs students Our curricula comply with Common Core Standards and when appropriate with subject area standards. Recommendations for an interdisciplinary approach Assessment tools Our developmentally appropriate and culturally sensitive materials support various learning styles and promote literacy. We fully support Teaching Tolerance’s Anti-bias Framework in Education.", "pred_label": "__label__POS", "pred_score_pos": 0.5250110030174255}
{"content": "Naples, Fl. (November 22, 2019) – As predicted by a group of Naples real estate brokers, buyer activity began to rise in October with a remarkable 23.7% increase in overall pending sales (homes under contract) to 987 pending sales during October 2019 compared to 798 pending sales in October 2018. Sellers also felt a surge in showings (up 40% compared to October 2018), and the number of price reductions slowed to just 15% of the properties available in October’s overall inventory compared to September, which saw 26% of its inventory’s prices reduced. Price reduction activity is an important behavior for buyers to watch as it is an indication of how eager sellers are to sell. Closed sales during October increased 9.7% to 758 closed sales compared to 689 closed sales in October 2018, according to the October 2019 Market Report released by the Naples Area Board of REALTORS® (NABOR®), which tracks home listings and sales within Collier County (excluding Marco Island).", "pred_label": "__label__POS", "pred_score_pos": 0.9899759292602539}
{"content": "Does technology amplify adverse herding among inexperienced investors? In their October 2020 paper entitled \"Attention Induced Trading and Returns: Evidence from Robinhood Users\", Brad Barber, Xing Huang, Terrance Odean and Christopher Schwarz test the relationship between episodes of intense stock buying by retail (Robinhood) investors and future returns. Their source for buying intensity is the stock popularity feature of Robintrack from May 2, 2018 until discontinuation August 13, 2020 (with 11 dates missing and two hours missing for 16 other dates), during which the number of Robinhood user-stock positions grows from about 5 million to over 42 million. They define intense stock buying (herding event) as a dramatic daily increase in number of Robinhood users owning a particular stock in two ways:\nAmong stocks with at least 100 owners at the start of the day, select those in the top 0.5% of ratio of owners at the end of the day to owners at the beginning of the day. Select stocks with at least 1,000 new owners and at least a 50% increase in owners during the day.\nUsing Robintrack data supporting these definitions and associated daily stock returns, open and close prices, closing bid-ask spreads and market capitalizations,\nthey find that:", "pred_label": "__label__POS", "pred_score_pos": 0.7114179134368896}
{"content": "Does adding international equity exposure and an escape to \"cash\" enhance performance of a relative momentum strategy that switches between stock and U.S. Treasury bond exchange-traded funds (ETF)? In his February 2018 paper entitled \"Simple and Effective Market Timing with Tactical Asset Allocation Part 2 - Choices\", Lewis Glenn updates and considers two extensions to a strategy summarized in \"Simplest Asset Class ETF Momentum Strategy?\" that each month holds SPDR S&P 500 (SPY) or iShares Barclays 20+ Year Treasury Bond (TLT) depending on which has the higher total return over the last three months. Specifically, the three strategies are:\nPair Switching (PS) - the original strategy as described above. Quint Switching (QS) - adds iShares MSCI EAFE (EFA), PowerShares QQQ (QQQ) and iShares MSCI Emerging Markets (EEM) to the asset universe, each month picking the top performer. Quint Switching Filtered (QSF) - modifies QS by adding a rule that if any of SPY, TLT, EFA, QQQ and EFA have non-positive returns over the lookback interval, switch to iShares Barclays 7-10 Year Treasury (IEF) .\nFor all strategies, he includes 0.1% switching frictions for each buy and sell action. He focuses on compound annual growth rate (CAGR) and maximum drawdown (DDD\nmax) as key strategy performance metrics. He considers momentum ranking (lookback) intervals of 1 to 5 months to determine the optimal interval for the two strategy extensions. Using monthly dividend-adjusted closes of the specified funds during April 2004 through January 2018, he finds that:", "pred_label": "__label__POS", "pred_score_pos": 0.5600728988647461}
{"content": "View from the House: A critical moment for our country PUBLISHED: 09:00 14 November 2020\nFREE TO USE\nWe are at a critical moment for our country, with a rise in infection rates, hospital admissions, and tragically, the number of deaths.\nYou may also want to watch:\nI’m glad that the government has finally taken the decision to bring in lockdown restrictions, but this should have been done weeks ago. The government chose to ignore the guidance from its own scientific advisers and wasted valuable time which will come at an economic cost and a human cost.\nThis government needs to act fast. We desperately need a test, track and trace system that works. Instead of wasting billions of pounds on private contractors such as SERCO who have failed to deliver, the government should be working collaboratively with local health providers and local authorities. This is the only way to prevent the spread of Covid-19 and enable us to get out of the cycle of lockdowns and damage to lives, livelihoods and the wider economy.\nIf you value what this story gives you, please consider supporting the East London Advertiser. Click the link in the orange box above for details.", "pred_label": "__label__POS", "pred_score_pos": 0.9367043375968933}
{"content": "Rare genomic changes as a tool for phylogenetics. Rokas A., Holland PW.\nDNA sequence data have offered valuable insights into the relationships between living organisms. However, most phylogenetic analyses of DNA sequences rely primarily on single nucleotide substitutions, which might not be perfect phylogenetic markers. Rare genomic changes (RGCs), such as intron indels, retroposon integrations, signature sequences, mitochondrial and chloroplast gene order changes, gene duplications and genetic code changes, provide a suite of complementary markers with enormous potential for molecular systematics. Recent exploitation of RGCs has already started to yield exciting phylogenetic information.", "pred_label": "__label__POS", "pred_score_pos": 0.8690526485443115}
{"content": "Over 60 educators have participated in #edchat discussions. Will you collaborate with us to create educational change?\nAlthough relatively new, #edchat has become an incredible collaborative tool for educators to debate and evaluate solutions to various problems through Twitter. Over 60 educators and administrators have contributed to the #edchat discussions from various countries around the world. In what other forum would this be possible?\nMr. Regier sees things evolving fairly rapidly, accelerated by the increasing use of social networking technolo\nThe real promise of online education, experts say, is providing learning experiences that are more tailored to individual students than is possible in classrooms. That enables more “learning by doing,” which many students find more engaging and useful.", "pred_label": "__label__POS", "pred_score_pos": 0.5191259384155273}
{"content": "Persons using assistive technology may not be able to fully access information in this file. For assistance, please contact us.\nStructured Abstract Objectives\nReviewers often employ a \"best evidence\" approach to address the key questions, but what is meant by \"best\" is often unclear. The goal of this project was to create a decision framework for \"best evidence\" approaches in systematic reviews. This document is not intended to be prescriptive, but rather to provide a conceptual construct to enhance the transparency of inclusion decisions made during the course of a systematic review.\nReview Methods\nWe set out to accomplish the following tasks: (1) create a list of possible inclusion criteria, and for each criterion, create a list of factors that might affect a reviewer's decision to use it, (2) create a list of evidence prioritization strategies, and (3) list the ways in which evidence prioritization strategies might be formally evaluated. In a series of conference calls, collaborators from five Evidence-based Practice Centers discussed methods for accomplishing the tasks noted above. After the initial conference call, the project leaders prepared a series of discussion documents specific to the first three tasks. Subsequent conference calls were scheduled to discuss comments and suggestions from the collaborators, whose feedback was incorporated in revisions in the task documents. The document was then externally reviewed by experts from other institutions, and revisions were made based on reviewer comments.\nResults\nFor Task 1, we identified 21 potential inclusion criteria and 15 modifying factors a reviewer should consider when deciding which criteria to employ. The inclusion criteria were divided into three categories: criteria pertaining to study design, criteria pertaining to study conduct and reporting, and criteria pertaining to relevance. A flow chart of the decision process provides a guide to reviewers, and tables illustrate the factors influencing decisions about each inclusion criterion. For Task 2, we identified four strategies for prioritizing evidence. For Task 3, we identified a number of potential approaches that might be used to formally evaluate these strategies in the future.\nConclusions\nSystematic reviewers routinely prioritize evidence in numerous ways. This paper provides a framework for understanding the possibilities, considering influential factors, and choosing among the myriad options. This will help enhance the transparency of review processes, which in turn may help users determine how different reviews of the same topic can reach different conclusions.", "pred_label": "__label__POS", "pred_score_pos": 0.830436646938324}
{"content": "From Name:From Email:To Name:To Email:Optional Message:Many new moms do not admit postpartum mental health issuesfrom Psych CentralAlthough it is commonly acknowledged that pregnancy can lead to postpartum mood disorders, over 20 percent of new moms do not discuss their symptoms with healthcare providers. North Carolina State University researchers found that 21 percent of recent mothers experiencing conditions such as anxiety and depression, fail to inform their healthcare team.more7701 Las Colinas Blvd., Ste. 800, Irving, TX 75063", "pred_label": "__label__POS", "pred_score_pos": 0.7897851467132568}
{"content": "COVID-19: Transportation Response Center\nTransit streets are designed to move people, and should be evaluated in part by their ability to do so. Whether in dense urban cores, on conventional arterials, or along neighborhood spines, transit is the most spatially efficient mode.\nTraditional volume measures fail to account for the entirety of functions taking place on urban streets, as well as the social, cultural, and economic activities served by transit, walking, and bicycling. Shifting trips to more efficient travel modes is essential to upgrading the performance of limited street space.\nUsing person throughput as a primary measure relates the design of a transit street to broader mode shift goals.\nThe capacity of a single 10-foot lane (or equivalent width) by mode at peak conditions with normal operations.\n60 people per meter per minute, allowing 1.5 sq. meters per pedestrian and a 75 meter per minute walking speed.\n“Ch 6, Bus Transit Capacity.” TCQSM, 3rd Ed. (2013).\nZhou et al. measured 2,500 bikes per meter per hour on cycle tracks in downtown Hangzhou.\nDan Zhou, et al. Estimating Capacity of Bicycle Path on Urban Roads in Hangzhou, China (2014).\nWhile street performance is conventionally measured based on vehicle traffic throughput and speed, measuring the number of people moved on a street—its person throughput and capacity—presents a more complete picture of how a city’s residents and visitors get around. Whether making daily commutes or discretionary trips, city residents will choose the mode that is reliable, convenient, and comfortable.\nTransit has the highest capacity for moving people in a constrained space. Where a single travel lane of private vehicle traffic on an urban street might move 600 to 1,600 people per hour (assuming one to two passengers per vehicle and 600 to 800 vehicles per hour), a dedicated bus lane can carry up to 8,000 passengers per hour. A transitway lane can serve up to 25,000 people per hour per travel direction. Read More+\nA reasonable planning-level capacity for a dedicated transit lane is 80 buses per hour; assuming 100 riders per vehicle (a comfortable articulated bus capacity), 8,000 riders per hour can be moved through a single transit lane. At two-minute headways (or 30 buses per hour), a standard 40-foot bus, assuming 60 passengers, moves 1,800 passengers per hour.\nHigh-capacity LRVs, running four cars per train with a capacity of 125 riders, have a capacity of 15,000 passengers per hour.\nTransportation Energy Data Book, edition 34 (2015).\nStreetcar and Light Rail Streetcar and Light Rail Characteristics. Regional Transportation District (2012).", "pred_label": "__label__POS", "pred_score_pos": 0.570244312286377}
{"content": "Projekteja vuodessa\nAbstrakti\nTrust plays a crucial role in online social networks where users do not communicate or interact with each other in a direct face-to-face manner. Although many researchers have already conducted comprehensive studies on trust computing like trust evaluation, pairwise trust prediction is still relatively under explored especially with machine learning methods which can overcome the disadvantages of both linear predication and trust propagation. This survey aims to fill this gap and first provides an overview of state-of-the-art researches in pairwise trust prediction using machine learning techniques, especially in the context of social networking. Specifically, we present a workflow of trust prediction using machine learning and summarize current available trust-related datasets, classifiers and different metrics used to evaluate a trained classifier. Also, we review, compare, and contrast the literature for the purpose of identifying open issues and directing future research.", "pred_label": "__label__POS", "pred_score_pos": 0.9962669610977173}
{"content": "The UK Government has proposed a new UK-wide Emissions Trading System (ETS) to replace the EU system, the UK Department of Business, Energy & Industrial Strategy (BEIS) announced Monday.\nThe system – designed by the UK Government jointly with the Scottish Government, Welsh Government and Northern Ireland Executive – includes plans to reduce the existing emissions cap by 5%, going further than the current EU system, the department said.\nIt stressed the new scheme would replace the EU ETS, which the UK will leave at the end of this year as the transition period ends for the UK to leave the EU.\nHowever, the UK would be open to considering a link between a UK ETS and the EU ETS, \"if it suits both sides’ interests,\" which is subject to the ongoing trade negotiations between the UK and EU, the department noted.\nOnce a new system is up and running the government intends to go even further by amending the cap again in line with its net-zero target.\n\"The UK is a world-leader in tackling climate change, and thanks to the opportunities arising as we exit the transition period, we are now able to go even further, faster,\" Energy Minister Kwasi Kwarteng, was quoted as saying.\nKwarteng asserted that this new scheme would provide a smooth transition for businesses while reducing the UK's contribution to climate change.\nThe department noted that elements of the new ETS will be familiar to operators and are designed to ensure a seamless transition at the end of the year.\nAround a third of UK emissions and around 1,000 UK factories and plants are currently covered by the EU ETS and will continue to be covered by the UK system.\nAccording to the department, the approach to free allocation of allowances under the new system will be consistent with what operators will expect under the EU ETS.\nBy Ebru Sengul Cevrioglu\nAnadolu Agency\nenergy@aa.com.tr", "pred_label": "__label__POS", "pred_score_pos": 0.7760860919952393}
{"content": "We present the adaptation of an IFCC method for α-amylase using 2-chloro-4-nitro-phenyl-α-D-maltotrioside as substrate (1) suited for routine work at 37℃. In the assay, a constant proportion of substrate, i. e. 92%, is directly converted to 2-chloro-4-nitrophenol and maltotriose. The method is based on multi- and univariate optimization leading to following measurement conditions: substrate, 2.25 mmol/l; chloride, 310 mmol/l; calcium 5.0 mmol/l; 4-morpholinoethanesulphonic acid, 50 mmol/l; pH 6.28. The assay may be carried out manually or by mechanized procedures, with substrate or sample start, and it shows these analytical properties in measuring amylase activity of sera: no lag phase, detection limit 2.9 U/l, linear range ≤820 U/l (for 300 s) or ≤1450 U/l (for 120 s of measurement), and total manual imprecision 3.2% (CV) at 46 U/l. Bilirubin ≤630 μmol/l, haemoglobin ≤6 g/l, triacylglycerols ≤30 mmol/l, heparin ≤100 kU/l, and glucose ≤120 mmol/l do not interfere. For adults, we established a preliminary 0.95-reference interval of 30–90 U/l not dependent on sex or age. A close association with the IFCC method demonstrates the reliable transfer of its measurement conditions to a robust routine method with minimal changes.", "pred_label": "__label__POS", "pred_score_pos": 0.9192581176757812}
{"content": "In its letter, EAPN expressed three key concerns and puts forward proposals to address them, to ensure a strong social dimension and balanced vision for the EU, backing social investment in social protection and promoting social rights:\nFar from reaching the European target of reducing the numbers living in poverty and social exclusion by 20 million by 2020, latest official figures show a rise of about 4 million people. There is enough evidence that this is directly related to the austerity policies. The resulting unemployment, poverty and inequality are feeding social unrest, xenophobia and racism that are undermining stability and social cohesion within, and between, EU Member States. EAPN welcomes the increasingly strong stance taken by Social Ministers in the EPSCO to promote “a balanced vision of social progress and social cohesion is crucial to restoring the confidence of citizens… this should emphasize fairness and equity in burden sharing and be reflected in the policies” 2but the policies pursued lack the necessary coherence to achieve such a vision. The EU, through its intervention on economic governance and the fiscal compact, has indirectly impacted on Member States’ social spending and isincreasingly intervening in their social policy. This raises key issues of legal legitimacy as well as democratic accountability and undermines trust in the EU project. This is in stark contrast to demands for positive cooperation to ensure high-level social standards in the EU, which is often blocked on the grounds of ‘subsidiarity’.\n/END/\nSee:\nLetter to Ministers for Social Affairs EAPN 2013 Assessment of Country Specific Recommendations and proposals for alternative CSRs from National and EO Members and Detailed Country Fiches EAPN Response to the Social Investment Package: Will the SIP deliver on poverty? (June 2013) For further information, contact Fintan Farrell (Director) fintan.farrell@eapn.eu (Tel. +32 2 226 58 50 – fax. +32 2 226 58 69 – or Nellie Epinat (Communications officer) Nellie.epinat@eapn.eu (+32 498 44 13 66)\n1. Employment, Social Policy, Health and Consumer Affairs Council (EPSCO)\n2. Letter from the Irish Presidency on social dimension of the EMU (15 May)", "pred_label": "__label__POS", "pred_score_pos": 0.8614212274551392}
{"content": "Abstract\nIn conscious newborns, the ventilatory response to hypoxia is characterized by precocious hyperventilation followed by tardive hypoventilation, the latter disappearing with age. The hypoventilation could be mainly related to a weak peripheral drive and to the persistence of the diaphragmatic activity during expiration. Also, a decrease in metabolic rate and body temperature interferes with the response. The hyperventilation in response to hypercapnia increases as maturation proceeds and the maturation of the peripheral chemoreceptors contribute to this effect, as during hypoxia. The responses to both stimuli depend on many factors such as sleep state, anesthesia or ambient temperature.", "pred_label": "__label__POS", "pred_score_pos": 0.8142068982124329}
{"content": "The Business of Decolonization serves to deepen our understanding of the end of the British empire, too often approached as if it was a process shaped and experienced exclusively by nationalist and imperial politicians and policy-makers. It explores British companies' experience of, and involvement in, developments leading to the transfer of power in Ghana, the former colony of the Gold Coast. The book demonstrates that businessmen developed strategies to cope with political change, reveals the extent of their involvement in nationalist politics, and highlights the contrasting responses of different companies to political and constitutional developments in the colony. Drawing on an extensive range of company, business association, personal, and official papers, the book focuses primarily on company activity. However, it also investigates relations between British firms and the colonial state on the eve of Ghanaian independence, and examines the place of British business interests in British policy.\nProduct code: 9780198208488\nISBN 9780198208488 Dimensions (HxWxD in mm) H224xW144xS21 Series Oxford Historical Monographs No. Of Pages 276 Publisher Oxford University Press", "pred_label": "__label__POS", "pred_score_pos": 0.9298924207687378}
{"content": "The Job Description of a Legal Cashier\nIndividuals with an interest in the legal field who enjoy bookkeeping and handling payments should consider becoming legal clerks. With the legal field growing at a faster than average rate compared with other jobs, according to the U.S. Bureau of Labor Statistics, employment opportunities for legal clerks is expected to grow.\nEducation and Experience\nThough a college degree can make individuals more competitive applicants, most employers only require legal clerks to have a high school diploma or equivalent education. Previous experience working as a legal cashier, accounting secretary, or in the legal field are necessary since this is not typically an entry-level position.\nSkills\nLegal cashiers must be proficient in computer use and the Microsoft system. Typically employers place an emphasis on previous experience using Microsoft Excel or spreadsheet software. Additionally, applicants for these positions should demonstrate excellent communication skills both in person and while answering the telephone. They should have strong writing skills, place emphasis on details, and be trustworthy since their job entails working with money. They must be highly organised and be able to work well independently.\nDuties\nThese professionals are in charge of bookkeeping, and aid in the financial management of accounts for the law firm. Legal cashiers receive payments for goods and services such as food, rent, deposits, accounts receivable, and fees. They work a cash register or computer to register these payments. They must check the identification of customers who use checks or charge accounts. They must accurately count the amount of money in the register at the end of each shift. Additionally, they collect and issue refunds as well as record daily transactions. They must write checks and review bank accounts. These professionals must maintain knowledge of legal proceedings as well as the company's financial software.\nWork Environment\nLegal cashiers spend most of their day in an office, working behind a desk or tellers window. Though they work with many people throughout the day taking payments, they typically have minimal supervision. Usually, their schedule follows the standard 40-hour work week though some legal cashiers chose to work part-time.\nSalary\nAccording to a 2009 survey from CBSalary.com, the average annual salary for a legal clerk is £27,551 per year. Salaries, however can range from £22,324 to £41,583 per year. As with all salary surveys, these figures can vary significantly based upon experience, employer, and geographic location.", "pred_label": "__label__POS", "pred_score_pos": 0.989776611328125}
{"content": "Modern organizations rely on 2 strategic factors for success: information & technology (I&T). Reality proves that I&T is a critical and multi-dimensional success factor, affecting almost any business activity and unit;thus, it needs to be governed using a multitude of components (e.g. processes, organizational structures, information flows and behaviors). All these components should work together, holistically.\nGovernance of Enterprise Information and Technology (GEIT) is an activity which allows stakeholders to engage in setting direction and monitoring performance against enterprise objectives while addressing the complex regulatory environment of various industries and jurisdictions as well, by\ndesigning, implementing and sustaining a governance system.\nUltimately, organizations that establish and maintain a governance system achieve operational excellence by executing their business strategy in a consistent and reliable way, reducing operational risks and costs while increasing competetive revenue.\nOur GEIT Approach\nHaving a team of skilled and certified governance consulting professionals, we assist you on your governance program journey from the early system design to implementation, continuous oversight and improvement, in a 4-phase approach.\nDespite the fact that a governance system should be holistic and describe end-to-end processes and components within the organization, our GEIT approach can also be applied to organizations focusing only on specific topics or issues, such as critical, business-enabling compliance matters.\nKeep in mind that no silver bullet exists for the design of a GEIT system. Since every enterprise has its own distinct character, profile, business, industry and regulatory environment, threat landscape, IT dependence and strategic components, a tailor-made approach is the only way to achieve successful setting and implementation.", "pred_label": "__label__POS", "pred_score_pos": 0.5641498565673828}
{"content": "Majority believe cashless society will leave some groups behind\n7 June 2019 | 0\nA Dublin Mint Office study has revealed that 88% of people believe a cashless society will exclude some societal groups.\nThe study involved 562 participants and was conducted by the Dublin Mint Office, a private company that sells commemorative coins.\nIts respondents believe the measure could exclude vulnerable groups like the elderly, homeless people and small businesses.\nAdditionally, it found that 68% of participants are against the prospect of a cashless society.\nLeinster is the providence most in favour of a cashless society, with 38% welcoming the measure. Munster is the most opposed, with just 23% supporting it.\nOf those surveyed, 57% favour using cash, as it offers more privacy and is more widely accepted than other forms of payment.\nFor the 43% who prefer using card or digital payment methods, the most commonly cited reason was convenience.\nWhile 55% believe cashless payment is less secure than physical currency, 66% find it more convenient than using cash.\nTechCentral Reporters", "pred_label": "__label__POS", "pred_score_pos": 0.99906325340271}
{"content": "This year, consumers in Greece – stressed by the multitude of taxes, which must be paid by the end of December – have yet again limited their Christmas spending to the bare essentials.\nMoreover, given that consumer spending in December this year amounts to roughly €3.22 billion, it is clear that the decline in retail turnover is 42% compared to December 2009, when the Greeks spent 5.6 billion.\nThe Institute for Trade and Services of the National Confederation of Commerce estimates that in December 2015 retail turnover has shrunk by a further 8.3% compared with the same period of 2014. This fact is attributed to a whole series of events, which have affected adversely both the psychology of consumers and the smooth operation of businesses.\nThe following retail sectors have seen the steepest decline in December since 2009: household appliances - 56.1%, clothing and footwear - 42.9%, pharmaceutical and cosmetic products - 38.1%, fuel - 28.8%, books and stationery - 28.1% and food products - 19.9%.", "pred_label": "__label__POS", "pred_score_pos": 0.9459800720214844}
{"content": "This week is National Reconciliation Week, a time for all Australians to learn about our shared histories, cultures, achievements and relationship with Aboriginal and Torres Strait Islander People. It is an opportunity to explore how each of us can contribute to achieving reconciliation.\nBetween Monday 27 May and Monday 3 June, we commemorate two significant milestones in the reconciliation journey – the anniversaries of the 1967 Referendum which included Aboriginal people within the constitution and the High Court Mabo decision, which acknowledged the unique connection with the land for Aboriginal people.\nMany of our established climbing areas have significant meaning to the traditional custodians of the land. As climbers, it is important to understand the cultural heritage of the Traditional Owners and to preserve and respect the traditional owners connection to the land.\nThis year, the theme of National Reconciliation Week is\n‘Grounded in Truth, Walk Together with Courage’. “To foster positive race relations, the relationship between Aboriginal and Torres Strait Islander peoples and the broader community must be grounded in truth. Whether you’re engaging in challenging conversations or unlearning and relearning what you know, this journey requires all of us to walk together with courage.” Reconciliation Victoria\nACAV encourages all its members to take a moment to reflect on the significance of this week and to participate in National Reconciliation Week activities happening across the state. You can also plan your own event. To find a list of events taking place in your area please visit https://www.reconciliation.org.au/national-reconciliation-week/nrw-events/\nFrom the ACAV Interim Committee", "pred_label": "__label__POS", "pred_score_pos": 0.9908700585365295}
{"content": "Previously, I highlighted three steps a company must take to unlock the business value of Microsoft Office 365 (O365). In the final blog of this series, I explain how to get started with O365 and implement true change.\nOrganizations must continue to transform to keep up with, or exceed, customer, business, and employee expectations. As digital transformation persists, there are increasing demands for digital dexterity in the workforce. According to Gartner, “Digital dexterity will be a significant driver of competitive advantage (or disadvantage, in the case of digital deficiency) for the foreseeable future. So, helping employees productively use new cloud office workloads can be a key element of a digital dexterity plan.”\nO365 provides the tools and services to achieve superior digital dexterity. However, it does not happen through mere exposure to O365 tools. It is necessary to carefully consider the six steps outlined in this series. These steps help can drive the adoption of O365 and achieve its inherent business value.\nGetting It Right\nWe take you through 10 best practices, considerations, and suggestions that can enrich your Microsoft Teams deployment and ensure both end-user adoption and engagement.\nWhen change management is done well it is a beautiful thing. People are engaged with the right messages, in the right ways, at the right time. They understand why the change is being implemented. They buy into what the new system or process means to them. Because they buy-in, they seek – yes proactively seek – more information and are simply excited for the results that will come in the new environment. They attend training and absorb the content. At go-live, they are engaged, which minimizes disruption and enables the project to realize operational benefits quickly.\nChange management increases the probability of staying on schedule and budget, resulting in higher benefit retention and ROI.\nWhy Perficient\nOur team of organizational change management professionals applies broad-based business experience and expertise to mitigate the people-related risks of change programs. We help you manage the transition process to ensure your team is ready, willing, and able to perform effectively in the new environment.\nTo learn more, download this guide here to explore the six steps required to begin unlocking the true value of O365, or you can submit the form below.", "pred_label": "__label__POS", "pred_score_pos": 0.735649824142456}
{"content": "Is Your IoT Deployment Secure?\nTransportation and logistics companies recognize they must strengthen their approaches to cybersecurity but are not yet taking the practical steps to safeguard their industrial Internet of Things (IoT) deployments, according to a study done on behalf of Inmarsat.\nAccording to the study, which surveyed 125 businesses across the transport industry, 64% of respondents say their processes to combat cybersecurity threats could be stronger, and two thirds (66%) say more could be done to protect against data mishandling.\nDespite recognizing the enhanced security threats of Industrial IoT, just 38% have invested in new security technologies and only 39% have partnered with security specialists for assistance, indicating that not enough is being done to secure operations. One driver for this response is a lack of relevant skills, with 59% of respondents reporting they lacked staff with cybersecurity skills to deliver their Industrial IoT deployments.", "pred_label": "__label__POS", "pred_score_pos": 0.8735169172286987}
{"content": "The Achilles' heel of iron-based catalysts during oxygen reduction in an acidic medium† Abstract\nFor catalysing dioxygen reduction, iron–nitrogen–carbon (Fe–N–C) materials are today the best candidates to replace platinum in proton-exchange membrane fuel cell (PEMFC) cathodes. Despite tremendous progress in their activity and site-structure understanding, improved durability is critically needed but challenged by insufficient understanding of their degradation mechanisms during operation. Here, we show that FeN\nC x moieties in a representative Fe–N–C catalyst are structurally stable but electrochemically unstable when exposed in an acidic medium to H y 2O 2, the main oxygen reduction reaction (ORR) byproduct. We reveal that exposure to H 2O 2leaves iron-based catalytic sites untouched but decreases their turnover frequency (TOF) viaoxidation of the carbon surface, leading to weakened O 2-binding on iron-based sites. Their TOF is recovered upon electrochemical reduction of the carbon surface, demonstrating the proposed deactivation mechanism. Our results reveal for the first time a hitherto unsuspected key deactivation mechanism during the ORR in an acidic medium. This study identifies the N-doped carbon surface as the Achilles' heel during ORR catalysis in PEMFCs. Observed in acidic but not in alkaline electrolytes, these insights suggest that durable Fe–N–C catalysts are within reach for PEMFCs if rational strategies minimizing the amount of H 2O 2or reactive oxygen species (ROS) produced during the ORR are developed.", "pred_label": "__label__POS", "pred_score_pos": 0.7778700590133667}
{"content": "SECTION27 welcomes the Western Cape High Court’s decision to block plans by government to proceed with the unlawful and unconstitutional nuclear deal.\nWe specifically pay tribute to Earthlife Africa and the Southern African Communities’ Environment Institute for their tireless work, advocacy and activism. We always knew that should this deal – which our country cannot afford – be signed, generations would be paying off this massive debt. The court ruling is another significant blow against corruption.\nCivil society organizations are one of the final hurdles against further state capture and we urge foundations, donors and South Africans to do all they can to support these entities.", "pred_label": "__label__POS", "pred_score_pos": 0.7618950605392456}
{"content": "Why Demand for Digestive Health Keeps the Probiotics Market Growing\nThe probiotics market is growing. Why? Over the past five years, the number of internet searches for “Gut Health” has grown by 669%. With greater interest in digestive health, food and beverage manufacturers have an opportunity to meet consumers with the benefits they demand. The first step is understanding your prospective buyers to create a better food or beverage product that meets their interests.\nThis white paper explores a new global consumer survey, offering unique insights about: Factors driving growth of the digestive health category and probiotics market. Consumers’ expectations of digestive health products. Geographic variations in terms of awareness and intent to purchase. Probiotic solutions for meeting demand. To download this white paper, please fill out the form.", "pred_label": "__label__POS", "pred_score_pos": 0.5102590322494507}
{"content": "What does your data mean to you? Ever wondered how to draw strong insights from data? For a driven firm, it is quite important. The presentation of this data is vital for your team as its analysis directly influences the following actions. The issue though is not every firm is able to accomplish this task which hinders their success. Forrester found that while 74% of firms say they want to be data-driven, only 29% are successful in connecting their analytics to action.[1] This statistic demonstrates that this is a problem for a majority of firms.\nThese issues occur for varying reasons; one common cause is the lack of a learning culture coupled with employees being accustomed to heuristic methods. This deters focus on utilizing the data through technology thus leading to weaker insights compared to competitors. Another problem is the lack of tools which allow for efficiency in generating value.[2] The missing piece to solving all of this? The right technological solutions.", "pred_label": "__label__POS", "pred_score_pos": 0.8466569781303406}
{"content": "Through major histocompatibility complex class Ia leader sequence-derived (VL9) peptide binding and CD94/NKG2 receptor engagement, human leucocyte antigen E (HLA-E) reports cellular health to NK cells. Previous studies demonstrated a strong bias for VL9 binding by HLA-E, a preference subsequently supported by structural analyses. However, Mycobacteria tuberculosis (Mtb) infection and Rhesus cytomegalovirus-vectored SIV vaccinations revealed contexts where HLA-E and the rhesus homologue, Mamu-E, presented diverse pathogen-derived peptides to CD8+ T cells, respectively. Here we present crystal structures of HLA-E in complex with HIV and Mtb-derived peptides. We show that despite the presence of preferred primary anchor residues, HLA-E-bound peptides can adopt alternative conformations within the peptide binding groove. Furthermore, combined structural and mutagenesis analyses illustrate a greater tolerance for hydrophobic and polar residues in the primary pockets than previously appreciated. Finally, biochemical studies reveal HLA-E peptide binding and exchange characteristics with potential relevance to its alternative antigen presenting function in vivo.\nJournal article\nNat Commun\n07/08/2018\n9\nAnimals, Antigen Presentation, CD8-Positive T-Lymphocytes, Cytomegalovirus, Enzyme-Linked Immunosorbent Assay, Epitopes, HEK293 Cells, Histocompatibility Antigens Class I, Humans, Killer Cells, Natural, Macaca mulatta, Mycobacterium tuberculosis, Peptides, Protein Binding, Protein Conformation, Simian Immunodeficiency Virus", "pred_label": "__label__POS", "pred_score_pos": 0.9484597444534302}
{"content": "By Samhita Social Ventures\nJuly 24, 2018\nRead Time: 3 min\nThe inaugural session of CSR Café was held on July 4, 2018 and at Cafe Zoe, and was facilitated by Luis Miranda, Trustee – Collective Good Foundation, Chairman – Centre for Civil Society and Chairman – CORO, The session was focused around the ‘The Five Ways CSR Heads Can Create Lasting Change.’\nParticipants shared their insights and experiences on managing multiple mandates as a CSR Leader, the struggle with engaging stakeholders, the need for more sectoral research and the potential for collaboration among themselves and with the government. The following is a summary of themes explored:\nFollow us on social media to keep updated about the valuable learning from this formidable community of CSR leaders. If you and your company are interested in participating in this forum, do reach out to us at [email protected]", "pred_label": "__label__POS", "pred_score_pos": 0.9873818159103394}
{"content": "Natilee McGruder\nOn my journey to a healthier me, I have recently started an elimination diet where I am cutting out known inflammatory foods such as dairy, meat, sugar, grains (rice, wheat, etc), starchy vegetables (beans and potatoes) and alcohol. It has been a challenging and eye-opening experience to keep my meals both satisfying and tasty. As […]\nAs we step into 2014, many of us have pledged (as we do every year) to focus on improving our health. Generally, we resolve to change our diet and exercise habits. While I certainly don’t begrudge anyone setting a goal and working towards it, my sense is that longer lasting changes tend to be ones […]", "pred_label": "__label__POS", "pred_score_pos": 0.5655954480171204}
{"content": "Five Cayuga County businesses have agreed to pay $50 fines after the local health department found they violated COVID-19 face covering rules.\nThree of the establishments — China Wok, McDonald's on Genesee Street and Speedway on State Street — are in Auburn. The other two are Dunkin' Donuts in Weedsport and New York Pizzeria in Cato.\nAt its meeting Tuesday, the Cayuga County Board of Health approved consent orders signed by the businesses, which acknowledged the violations and agreed to pay a modest penalty.\nThe fines followed inspections by the Cayuga County Health Department. The department found that the businesses weren't complying with the state face covering requirement. For businesses, including restaurants, workers must wear masks or face coverings at all times.\nAn employee at Dunkin' Donuts in Weedsport wasn't wearing an \"adequate face covering\" while preparing baked goods in the rear of the restaurant. The face covering was in her pocket at the time of the inspection, according to the department's documentation.\nTwo employees at New York Pizzeria in Cato weren't wearing face coverings when an inspector visited the restaurant. One employee who did not have a face covering engaged with customers, the inspector said, and the other worker was preparing food. After the inspector informed them of the mandate, the employees put on face coverings.\nThere were two employees at China Wok who also weren't wearing face coverings. One of the employees was waiting on customers at the time of the inspection. Another employee wasn't properly wearing a mask as she prepared orders.\nTwo employees at McDonald's on the city's west end weren't properly wearing masks, according to the inspector's report. One employee had their face covering below their nose while waiting on a customer. Another employee wasn't wearing the face covering while walking through the back of the restaurant.\nAt Speedway, a cashier did not properly wear a face covering while waiting on four customers, including the health department inspector. A customer also wasn't wearing a face covering while failing to maintain social distancing between the cashier and the inspector.\nUntil recently, the Cayuga County Health Department would educate businesses about the face covering mandate after the first complaint. If the department receives a second complaint, the business is inspected and a consent order could be issued. If the business commits repeat offenses, a board of health hearing is possible and they could face additional penalties.\nEileen O'Connor, the health department's director of environmental health, said Tuesday that they will skip the educational phase of the process. One reason she cited is the increase in COVID-19 cases and the time constraints the department faces in responding to the outbreaks.\n\"We think, at this point in the game, businesses should know, especially restaurants because we regulate restaurants and we have sent them emails regarding this, but we believe all businesses should know that masks are required,\" O'Connor said.\nSo far, 12 Cayuga County businesses — mostly restaurants — have paid fines after violating the face covering mandate.\nPolitics reporter Robert Harding can be reached at (315) 282-2220 or robert.harding@lee.net. Follow him on Twitter @robertharding.\nConcerned about COVID-19?\nSign up now to get the most recent coronavirus headlines and other important local and national news sent to your email inbox daily.", "pred_label": "__label__POS", "pred_score_pos": 0.6686007380485535}
{"content": "Description\nAt the end of World War II roughly 300,000 American GIs were deployed as occupation forces in Germany. Many of them quickly developed intimate relations with their former enemies. Those informal interactions played a significant role in the transformation of Germany from enemy to ally of the United States, argues Petra Goedde in her engrossing book.\nGoedde finds that as American soldiers fraternized with German civilians, particularly as they formed sexual relationships with women, they developed a feminized image of Germany that contrasted sharply with their wartime image of the aggressive Nazi stormtrooper. A perception of German \"victimhood\" emerged that was fostered by the German population and adopted by Americans. According to Goedde, this new view of Germany provided a foundation for the political rapprochement that developed between the two countries even before the advent of the Cold War. Her provocative findings suggest that the study of foreign relations should focus on interactions not only between politicians and diplomats but also between ordinary citizens.", "pred_label": "__label__POS", "pred_score_pos": 0.836081862449646}
{"content": "Arizona law defines sexual harassment as any unwanted conduct of a sexual nature, whether they are verbal advances or physical acts. Some forms of sexual harassment that are most commonly committed by an employer include exchanging favoritism for sexual favors, the creation of a hostile work environment of a sexual nature, and sexual advances.\nHow does Arizona Law Prohibit Sexual Harassment?\nFirst, Youngtown employers can be required to formulate company policies that specifically address sexual harassment in the workplace. These must be posted in a visible area such as a break room. Matters covered by such policies should include contact information used by employees to report incidents, handling procedures for claims, and corrective measures (in the event that a claim turns out to be successful).\nFurthermore, federal and Arizona laws create specific agencies which are responsible for handling sexual harassment cases. The agencies are given authority to investigate workplaces in Youngtown to determine if the incidents alleged in the complaints they receive are true. Employers are also barred under these laws from taking action in retaliation against an employee who has claimed sexual harassment, such as firing them or denying them a promotion.\nHow can a Arizona attorney help?\nIt can be difficult to both investigate and show a sexual harassment claim without having any expertise in the applicable areas of law. It's not uncommon for federal investigators to be too overworked to handle individual claims. Thus, hiring an attorney in Youngtown can be the safest way to file your claim within the deadlines for sexual harassment claims that Arizona has defined.", "pred_label": "__label__POS", "pred_score_pos": 0.5108599662780762}
{"content": "Scientific reports, 9(1), p.2203. Larus michahellis, mitoQ supplementation increased the early growth rate of chicks but did not reduce mtDNA damage. The level of mtDNA damage was negatively correlated with chick mass, but this relationship was not affected by the mitoQ treatment. We also found that chick growth was positively correlated with both mtDNA copy number and the mitochondrial enzymatic activity of citrate synthase, suggesting a link between mitochondrial content and growth. Additionally, we found that mitoQ supplementation increased mitochondrial content (in males), altered the relationship between mtDNA copy number and damage, and downregulated some transcriptional pathways related to cell rejuvenation, suggesting that scavenging mtROS during development enhanced growth rates but at the expense of cellular turnover. Our study confirms the central role of mitochondria modulating life-history trade-offs during development by other mechanisms than mtROS-inflicted damage.", "pred_label": "__label__POS", "pred_score_pos": 0.8552550077438354}
{"content": "5-22-2020| Jessica Baumgardner-Zuzik, Shaziya DeYoung, and Uzra Zeya\nCOVID-19 is much more than a public health emergency. It is essentially\n“stabilization in reverse,” upending economies and societies, fueling division and distrust of government, and exacerbating drivers of violent conflict globally, especially in fragile and conflict-affected states. And yet, at a moment when peacebuilding is needed most, we are facing a potential systemic loss in peacebuilding capacity globally due to the disruptions wrought by the ongoing global pandemic.\nThis report highlights findings from April 29-May 11, 2020 survey responses of 60 AfP member CEOs, representing peacebuilding organizations across the globe. The results point to existential threats to peacebuilding efforts posed by COVID-19. Findings were further analyzed across small-scale (69%), medium-scale (14%), and large-scale (17%) organizations within participating respondents.", "pred_label": "__label__POS", "pred_score_pos": 0.9986348152160645}
{"content": "Organisation: Australian Border Force Job Title: Client Services Word Limit: 2000 Characters pp Location: Queensland\nContributes to Strategic Thinking\nThroughout my career, especially within the government sector, I have developed the ability to think logically, understand situations from a strategic perspective and follow through by formulating and implementing effective short-term and long-term decisions.\nWithin the Australian Taxation Office (ATO), as a Customer Service Representative, I practice informed decision-making and possess sound judgement with recognition of implications. Contributing to solutions and progress, I harness information and opportunities when performing my day-to-day duties, constantly working diligently to adhere with existing practices to improve efficiency.\nDuring my tenure with ATO, I recently during a shift as a floor walking support staff I provided support to a recently trained team member with a highly irate customer. This customer was threatening to make an official complaint and demanding to speak with a manager, as they were not happy with the current Customer Service Representative attempts at resolution. As managers are not technically trained, my manager called on my expertise to manage this call. In order to adhere to corporate procedures, I worked with this customer to establish a level of trust that was established in the competence of my ability to listen, empathise and educate in internal processes. Upon investigation into the customer’s issue regarding a payment into the incorrect account, I could identify that prior escalation had already been actioned but the relevant department had not actioned accordingly to service level agreements (SLA). In my senior team member access, I was one of few that could instigate direct payment if corporate polices and measurables were not met. With the customer now aware of the transfer of payment, I had calmed the situation by providing a practical solution in line with authority levels. Further to this, I also took the opportunity to educate the customer on future management of their accounts to eliminate reoccurrence of this issue.\nAchieves Results\nA self-motivated, results-orientated professional, I take responsibility for achieving outcomes within my position as a Customer Service Representative with the ATO. My accomplishments within this position include meeting targets, mentoring and training staff, leading by example, and supporting improvements to systems and procedures.\nMy ability to achieve results in a protocol and results driven environment best demonstrated during my position with ATO. Consistently exceeding customer expectations, I display my strong desire to excel in all business areas whilst striving for excellence.\nWhilst currently employed with ATO in the capacity of Customer Service Representative, I received a call from a customer who was a sole trader and currently in payment arrangement with the ATO. The customer had been defaulting on his obligation of agreed payment amounts and was confused with the arrival of separate additional invoices that were also due for payment. In line with ATO policy, I was not in a position to offer many alternatives to him but instigated recent training techniques I had acquired in recent internal debt collection training. Through the techniques gained, I initiated questioning to break down the customers’ financial capacity of payments and reviewed the customers’ situation in its entirety rather than traditional dictated methods used by the ATO. This allowed client to realise they did not have the surplus cash flow to meet their original plan, I proceeded to enter an arrangement that was substantial and could be committed to by customer. The outcome of my results driven methodology was that the customer was better educated and my key performance targets were high due to level of debt recovery. With this\npositive and practical outcome, I was then asked to train other staff on this approach and received positive feedback from the ATO national accredited quality register on my handling of that call.\nSupports Productive Working Relationships\nDemonstrating myself as an active team member, I have been instrumental in contributing to exceptional teams throughout my career history. Committed to team performance and often assisting others, I am prepared to work overtime or complete additional tasks to help team members or management.\nDuring my tenure with ATO as Customer Services Representative, I was awarded the opportunity to step into a mentoring capacity within the team responsible in coaching new staff. Having just completed internal training, they are yet to display their skills in a practical setting, I am responsible in the support and coaching in corporate procedures. The staff were having difficulty in following a nine-step call procedure due to its involvedness, I acknowledged the concerns of the team and initiated development of a condensed document that still adhered to policies. The outcome of my initiative was that they staff were able to follow the direction to completion and decreased times on calls with the confusion since removed. In demonstrating my commitment to corporate and internal cultivating relationships’, I improved the efficiency of the team, built trust and rapport from colleagues and received a personal thank you from the Assistant Director for my efforts.\nEstablished as a collaborative team member, I have formed constructive relationships with all stakeholders ensuring processes followed and culture within the company upheld. Possessing the ability to act in an inclusive manner and the initiative often required building productive relationships, I have been successful in building rapport in all network settings and interactions.\nExhibiting a commitment to supporting constructive working relationships, I manifest this by valuing individual difference and diversity and recognising working styles of individuals and factoring this into the management of tasks.\nDisplays Personal Drive and Integrity\nDemonstrating a high level of motivation, personal drive and integrity, I have successfully balanced work with the ability to multitask and remain focused. My career to date has involved diverse responsibilities, such as mentoring and training and embracing customer-based service delivery models, which have enabled me to develop excellent personal and professional skills. With a demonstrated record of commitment, consistency and a focus on quality service and outcomes, I possess practical experience and a range of professional skills and strengths that contribute to positive outcomes.\nWithin in my current position at the ATO, I am responsible in dealing with sensitive customer situations whilst adhering to strict legislation. Upholding core values of Australian Public Service, I apply ethical work practices and demonstrate integrity in all work practices. Striving for first call resolution outcomes in all interactions, I handled a customer querying their tax refund as it was outside delivery SLA. Although this customer initially was irate, I applied the Hearing them out, Empathy, Appropriate questioning and Take action (HEAT) model acquired through professional development training to understand the complaint and proceeded to explain how I would personally manage their concerns. Confirming my dedication to professional skills and career drive, I was successful in turning this call around including the customer apologising for his initial manner, providing a sound resolution adhering to all corporate legislation in this process.5\nIn a competitive work dynamic, I strive for professional development and advancement within my career. Embracing all opportunities offered, I was acknowledged as a top performer within team and was invited to complete a pilot program of debt collection training. Resilient and achievement orientated, I am dedicated to breaking down any barriers throughout my career to achieve optimum success for both business and my personal career growth.", "pred_label": "__label__POS", "pred_score_pos": 0.7580338716506958}
{"content": "As defensive security controls raise the bar to attack, attackers will employ increasingly sophisticated techniques to complete their mission. Understanding the mechanics and impact of these threats is essential to systematically discover and deflect the coming wave of advanced attacks.\nMandiant has developed a comprehensive whitepaper that provides a multi-faceted analysis of the exploit payload \"Operation RussianDoll.\" This payload is an exploit for CVE-2015-1701 embedded within the un-obfuscated 64-bit RussianDoll payload (MD5: 54656d7ae9f6b89413d5b20704b43b10). The whitepaper references a freely available open-source proof of concept and provides malware triage analysts, reverse engineers, and exploit analysts with tools and background information to recognize and analyze future exploits. It also covers how red team analysts can apply these principles to carve out exploit functionality or augment exploits to produce tools that will enhance effectiveness of security operations.\nThe whitepaper walks the reader through the payload's actions to understand how to loosely identify what it does once it has gained kernel privilege. It then discusses how to obtain higher-resolution answers from reverse engineering by using WinDbg to confirm assumptions, manipulate control flow, and observe exploit behavior. Building on this and other published sources, a technically detailed exploit analysis is assembled by examining the relevant portions of win32k.sys. Finally, the paper discusses how to extract and augment this exploit to load encrypted, unsigned drivers into the Windows 7 x64 kernel address space.\nWe hope this analysis will support security professionals' understanding of the malware used by Advanced Persistent Threat (APT) actors and of tools and techniques that may be used to conduct enhanced analysis.", "pred_label": "__label__POS", "pred_score_pos": 0.6947396993637085}
{"content": "Abstract: Context: Several decades of dietary research recommended the consumption of antioxidants and vitamins rich foods as a protective tool against a broad portfolio of diseases Aims: This study aims to test if oral supplementation of natural antioxidants and vitamins before the winter season, may reduce the occurrence of upper respiratory tract infection (URTI) in adolescents. Settings and Design: Natural antioxidants and vitamins supplements were given to 90 adolescents (45 males, and 45 females) from an orphanage against a placebo during three months in a double-blind fashion. Methods and Material: Saliva was collected before and after supplementation. The antioxidant activity of saliva was determined in vitro using electrolysis as a free radical generating system. Additionally, total antioxidant activity, glutathione and ascorbic acid levels in the saliva were evaluated before and after supplementation. The URTI frequency was recorded throughout the winter season (3 months). Statistical Analysis: All values were expressed as means ± SEM. Significance of the results was assessed using Student's t-test and Fisher’s test Results: Data indicated that only five individuals from the group that received antioxidants and vitamins supplements manifested URTI while 14 adolescents from the non-supplemented group showed symptoms of URTI. Biochemical analysis revealed that the saliva in provenance from the supplemented group exhibited a higher capacity to scavenge free radicals compared to its capacity before supplementation. This supplementation also increased the total antioxidant activity and the levels of both ascorbic acid and glutathione in the saliva. Conclusions: We concluded that oral intake of antioxidants and vitamins protects against URTI through increased antioxidant activity.\nKeywords : Antioxidants, vitamins, saliva, adolescents, upper respiratory tract infection (URTI).", "pred_label": "__label__POS", "pred_score_pos": 0.892791211605072}
{"content": "Relational Leadership demands that we take the time to generate that awareness, to understand how we both shape and are shaped by our culture, experiences, and social identities. The PCP mission does not directly address racial and restorative justice — but we can cultivate more awareness and identify actionable steps to take.", "pred_label": "__label__POS", "pred_score_pos": 0.9989199638366699}
{"content": "The space between commuters in public transport is shrinking to move the economy faster, increasing the risk of catching COVID-19. However, infections can be prevented by following what a panel of health experts called the\n\" Seven Commandments To Revitalize the Country Safely.\"\nThe same group, which includes\nformer health secretary Manuel Dayrit, submitted its recommendations on physical distancing in public transport to the Inter-Agency Task Force on COVID-19.\nHere are the\n\" Seven Commandments To Revitalize the Country Safely\" for commuters: Wearing of proper face masks Wearing of face shields No talkingand no eating Adequate ventilation Frequent and proper disinfection No symptomaticpassengers Appropriate physical distancing\n\"We believe that the combination of these measures will be amongst the most comprehensive in the world, based on our consultation with international experts. These 7 Commandments need to be strictly enforced and independently monitored in their implementation,\" the group said.\nImplementing the rules will allow the\ngradual relaxing of social distancing measures for a two-fold or even three-fold increase in passenger capacity without compromising public health, it said.\n\"The comparative toll on Filipinos from a further prolonged recession is much more devastating than the manageable risks entailed in our plan.\nWe believe that there is a way forward that carefully balances a careful reopening of public transport capacity, with public health, while allowing purposeful flexibility to re-adjust measures based on actual and evolving data from the ground.\"", "pred_label": "__label__POS", "pred_score_pos": 0.8595377802848816}
{"content": "Maintain\nThe maintenance of a qualification begins as soon as the qualification has been coded on SQA’s Awards Processing System (APS) and centres begin to deliver it.\nThrough delivering the qualification, tutors may come across issues around the structure and content of the qualification. For example, they may wish to suggest including an alternative Unit to meet a specific need, amending a Unit specification to clarify, simplify or correct something. External Verifiers may also identify issues around the assessment of the qualification through their verification visits to centres.\nIt is important that issues surrounding delivery and assessment of a qualification are identified, considered and addressed.\nMaintenance is about ensuring a qualification remains fit for purpose.", "pred_label": "__label__POS", "pred_score_pos": 0.8498164415359497}
{"content": "Hilary Stohs-Krause Why we worry about all the wrong things\nModern humans aren't great at risk assessment.\nWe often blithely ignore that which could harm us, and are conversely intimidated by things that are quite safe. This inability to recognize threat has vast implications for many aspects of our lives, including our careers.\nDo you want to be less stressed? Make better decisions? Learn strategies for identifying (and dealing with!) unnecessary worry? Let's explore the root causes of fear and anxiety together, and discover how we can start to deliberately rewrite our instincts.\nHilary Stohs-Krause\nHilary Stohs-Krause is currently based in Madison, WI, where she's co-owner and software developer at Ten Forward Consulting. She came to tech by way of childhood website-building (a \"Buffy the Vampire Slayer\" fansite, to be exact).\nShe volunteers regularly with several tech and community organizations, and co-runs Madison Women in Tech, a local group with more than 2,000 members. She loves sci-fi/fantasy, board games and bourbon barrel-aged stouts. She tweets at @hilarysk.", "pred_label": "__label__POS", "pred_score_pos": 0.6392192840576172}
{"content": "Staying out of debt is simple, but it’s not easy. It requires resilience — forgoing impulsive purchases in exchange for long-term financial freedom. Personal debt can be categorized as necessary or unnecessary. Necessary debt can generally be linked to assets such as your home mortgage, a basic car for getting to work, or a college degree. Unnecessary debt, on the…", "pred_label": "__label__POS", "pred_score_pos": 0.8993859887123108}
{"content": "Event\nOn Monday, January 27, Cambodian health authorities reported the first confirmed case of novel coronavirus (2019-nCoV) in the country. The individual infected is reportedly a Chinese national in Sihanoukville.\nFurther spread of the virus is possible in Cambodia over the near term.\nContext\nThe first case of 2019-nCoV was reported on December 31. The source of the outbreak has been linked to a wet market in Wuhan. Human-to-human and patient-to-medical staff transmission of the virus have been confirmed. Many of the associated fatalities have been due to pneumonia caused by the virus.\nThe World Health Organization (WHO) held an emergency panel in Geneva (Switzerland) on January 23 to discuss the virus, ultimately deciding that it was too early to classify the outbreak as a \"public health emergency of international concern.\" As of January 27, cases of the virus have been confirmed in France, Australia, Thailand, Japan, Malaysia, Indonesia, South Korea, the US, Vietnam, Singapore, Nepal, Macao, Cambodia, and Taiwan and suspected cases have been reported in Mexico and Cote d'Ivoire. The virus has killed 81 people and has infected over 2700 others.\nVirus screening measures are being implemented at airports worldwide.Pneumonia symptoms include dry cough, chest pain, fever, and labored breathing. Pneumonia can be contagious and can be transmitted from human to human. The influenza virus, or the flu, is a common cause of viral pneumonia.\nAdvice\nIndividuals who plan to travel to or have recently returned from China, particularly Hubei province, are advised to monitor the situation and prepare for flight disruptions. Individuals are advised to take precautionary measures to reduce their risk of contracting the virus:\nAvoid all contact with animals (dead or alive); avoid eating animal products that are undercooked; avoid all markets where animals are sold Avoid all close contact with people displaying symptoms of the disease (e.g. difficulties breathing) Individuals within China developing symptoms of pneumonia are advised to seek medical attention, avoid contact with other people, and wash hands regularly Frequently wash hands and wear a face mask Adhere to all instructions issued by the local authorities and their home governments", "pred_label": "__label__POS", "pred_score_pos": 0.5878539085388184}
{"content": "Sweep, dust, or vacuum the floor regularly with the hard floor attachment (not the beater bar) to prevent accumulation of dirt and grit that can scratch or dull the floor finish. For tough spots, such as oil, paint, markers, lipstick, ink or tar, use acetone/nail polish remover on a clean white cloth. Then wipe the area with a slightly damp cloth to remove any remaining residue. First test the method in a small less conspicuous area of the floor. For spots such as candle wax or chewing gum, harden the spot with ice and then gently scrape with a plastic scraper, such as a credit card. Be careful not to scratch the flooring surface. Wipe clean with a slightly damp cloth. Use a dry cloth to blot up spills as soon as they happen. Never allow liquids to stand on your floor for extended periods of time. Periodically clean the floor with cleaning products made specifically for laminate floor care. Spray the cleaner onto a dry swiffer or a microfiber mop, rather than spraying directly on to the floor. Do not use cleaning products such as Swiffer Wet Jet or Vileda Pro Mist that spray liquid directly onto the floor. Do not over use steam cleaners or wet mops, which may cause irreparable damage to your floor. Do not wash or wet mop the floor with soap, water, oil-soap detergent or any other liquid cleaning product. This could cause swelling, warping, delamination, and joint-line separation, and void the warranty. Avoid using steel wool, abrasive cleaners, or strong ammoniated or chlorinated type cleaners. Do not use any type of buffing or polishing machine on your laminate floors. A more frequent dust-mopping or vacuuming schedule may be required in very sandy areas such as a beachside home.", "pred_label": "__label__POS", "pred_score_pos": 0.8509770631790161}
{"content": "Cyclooxygenase-2 (COX-2) overexpression is an established factor linking chronic inflammation with metaplastic and neoplastic change in various tissues. We generated transgenic mice (BK5.COX-2) in which elevation of COX-2 and its effectors trigger a metaplasia-dysplasia sequence in exocrine pancreas. Histologic evaluation revealed a chronic pancreatitis-like state characterized by acinar-to-ductal metaplasia and a well-vascularized fibroinflammatory stroma that develops by 3 months. By 6 to 8 months, strongly dysplastic features suggestive of pancreatic ductal adenocarcinoma emerge in the metaplastic ducts. Increased proliferation, cellular atypia, and loss of normal cell/tissue organization are typical features in transgenic pancreata. Alterations in biomarkers associated with human inflammatory and neoplastic pancreatic disease were detected using immunohistochemistry. The abnormal pancreatic phenotype can be completely prevented by maintaining mice on a diet containing celecoxib, a well-characterized COX-2 inhibitor. Despite the high degree of atypia, only limited evidence of invasion to adjacent tissues was observed, with no evidence of distant metastases. However, cell lines derived from spontaneous lesions are aggressively tumorigenic when injected into syngeneic or nude mice. The progressive nature of the metaplastic/dysplastic changes observed in this model make it a valuable tool for examining the transition from chronic inflammation to neoplasia.", "pred_label": "__label__POS", "pred_score_pos": 0.9442075490951538}
{"content": "Artificial intelligence (AI) holds great promise to empower us with knowledge and scaled effectiveness. To harness the power of AI systems, we can—and must—ensure that we keep humans safe and in control. This session will introduce a new user experience (UX) framework to guide the creation of AI systems that are accountable, de-risked, respectful, secure, honest and usable.", "pred_label": "__label__POS", "pred_score_pos": 0.5272822380065918}
{"content": "Learning and Motivation\nIn order to deconstruct the neuronal basis of behavior, one must first understand the mechanisms underlying the behavior itself. These studies adopt sophisticated Pavlovian and instrumental procedures to examine the psychobiological variables underlying learning and decision-making.\nIngestive Behavior\nIn today’s obesogenic environment many individuals struggle to regulate caloric intake, which leads to obesity and associated comorbidities. As obesity rates continue to rise, there is a critical need to develop effective strategies to combat this epidemic. These studies examine the psychological and neurobiological variables underlying the regulation and dysregulation of energy intake.\nGhrelin’s influence on cue-evoked food seeking and intake Melanin Concentrating Hormone and cue-potentiated feeding Melanin Concentrating Hormone and orexin interactions within the lateral hypothalamus Neuropsychiatric Illness\nDysfunctions related to pleasure and reward are a hallmark of many neuropsychiatric illnesses (e.g., depression, schizophrenia). These studies identify endophenotypes of neuropsychiatric illness using animal models.\nDopamine and Learning\nStudies explore the role of dopamine in associative learning and decision-making. These studies use optogenetic and chemogenetic procedures to selectively stimulate and inhibit midbrain circuitry with a high degree of spatial and temporal resolution.\nThe role of the D2 receptor in effort-based decision-making Optogenetic stimulation of tyrosine hydroxylase", "pred_label": "__label__POS", "pred_score_pos": 0.5314575433731079}
{"content": "The\nFinancial Select Sector SPDR (NYSEArca: XLF), the largest financial services ETF, is lower by 3% over the past month, but some market observers believe the sector warrants renewed attention in the current interest rate climate.\nEarlier this year, financials were also propped up by a rise in bond yields as higher interest rates typically widen the margin spread between bank loans and deposits. The spreads will further widen as the Federal Reserve has stated its intentions to raise interest rates in response to economic growth and rising inflation.\nA steeper yield curve could help XLF and rival financial services ETFs rebound.\n“Banks get squeezed as a yield curve flattens, since they typically take on short-term debt to fund longer-term loans, and profit from the gap between the two rates. Conversely, a steeper yield curve would boost the margin,” reports Evie Liu for Barron’s.\nLooking for Financial Catalysts\nFundamental factors, including the aforementioned rising interest rates, have been supportive of bank stocks and ETFs this year. Additionally, the financial services sector, the second-largest sector weight in the S&P 500, has had the regulatory wind at its back this year as the Trump Administration has sought to roll back parts of the Dodd-Frank legislation. Still, the sector is disappointing investors.", "pred_label": "__label__POS", "pred_score_pos": 0.913364827632904}
{"content": "Acquisition and integration\nIntegration and acquisition are a routes to growth, even more so in times of economic stress. However, they carry a number of risks.\nWhether you are being acquired or seeking acquisition, we will help you mitigate these risks and ensure best value. From due diligence, to ensuring internal alignment and engagement, we know how to make it a success. Please send Claire Kinloch your brief today.", "pred_label": "__label__POS", "pred_score_pos": 0.6029901504516602}
{"content": "A news report, released by experts in international relocation, shows that Ireland is one of the top countries people move to from the United States, the United Kingdom, and Australia.\nMoveHub, which specializes in moving people abroad, released a report on global migration trends over the last 12 months. They report that were 22.2 percent more inquiries for moving to Ireland than moving out of Ireland during the past financial year (April 1, 2015 to March 31, 2016).\nThey also report that inquiries for moving to Ireland have increased by 6.9 percent compared with the prior fiscal year. During that same period interest in moving out of Ireland decreased by 0.9 percent.\nIt's good news following the massive outward migration during the recession. However, Ireland still has one of the highest levels of emigration in Europe – one person leaves every six minutes. According to the Central Statistics Office (CSO) 240 people leave Ireland each day.\nThe recent report from MoveHub was based on an analysis of over 180,000 inquiries regarding moving abroad along with an overview of the top 30 destinations and origin countries on a global scale.\nThe main points of the Global Moving Trends Report include:\n- 65% of moves are 'professional migrants,' meaning people moving for job opportunities and motivated by growing economies and better quality of life.\n- Ireland is one of the top countries people move to from Australia, the UK, and the USA.\nThe report also found that the top three reasons people move abroad are:\n- Employment - 34.8%\n- New experience - 29.7%\n- Join family 20.9%", "pred_label": "__label__POS", "pred_score_pos": 0.5018805265426636}
{"content": "KoreaMed, a service of the Korean Association of Medical Journal Editors (KAMJE), provides access to articles published in Korean medical, dental, nursing, nutrition and veterinary journals. KoreaMed records include links to full-text content in Synapse and publisher web sites.\nObjective This study aimed to investigate the potential correlation between baseline characteristics of individuals visiting an emergency room for a suicide attempt and subsequent psychiatric outpatient treatment adherence.Methods Medical records of 525 subjects, who visited an emergency room at a university-affiliated hospital for a suicide attempt between January 2017 and December 2018 were retrospectively reviewed. Potential associations between baseline characteristics and psychiatric outpatient visitation were statistically analyzed.Results 107 out of 525 individuals (20.4%) who attempted suicide visited an outpatient clinic after the initial emergency room visit. Several factors (e.g., sober during suicide attempt, college degree, practicing religion, psychiatric treatment history) were significantly related to better psychiatric outpatient follow-up.Conclusion Several demographic and clinical factors predicted outpatient adherence following a suicide attempt. Therefore, additional attention should be given to suicide attempters who are at the risk of non-adherence by practitioners in the emergency room.", "pred_label": "__label__POS", "pred_score_pos": 0.982272744178772}
{"content": "Consuming calories later in the day is associated with obesity and metabolic syndrome. We hypothesized that eating a late dinner alters substrate metabolism during sleep in a manner that promotes obesity.To examine the impact of late dinner on nocturnal metabolism in healthy volunteers.This is a randomized crossover trial of late dinner (LD, 22:00) versus routine dinner (RD, 18:00), with a fixed sleep period (23:00-07:00) in a laboratory setting.20 healthy volunteers (10 males, 10 females), aged 26.0 ± 0.6 years, BMI 23.2 ± 0.7 kg/m2, accustomed to a bedtime between 22:00-01:00.An isocaloric macronutrient diet was administered on both visits. Dinner (35% daily kcal, 50% carbohydrate, 35% fat) with an oral lipid tracer ([2H31] palmitate, 15 mg/kg) was given at 18:00 on RD and 22:00 on LD.Nocturnal and next-morning hourly plasma glucose, insulin, triglycerides, free fatty acids (FFAs), cortisol, dietary fatty acid oxidation, and overnight polysomnography.LD caused a 4-hour shift in the postprandial period, overlapping with the sleep phase. Independent of this shift, the postprandial period following LD was characterized by higher glucose, a triglyceride peak delay, and lower FFA and dietary fatty acid oxidation. LD did not affect sleep architecture, but increased plasma cortisol. These metabolic changes were most pronounced in habitual earlier sleepers determined by actigraphy monitoring.LD induces nocturnal glucose intolerance, and reduces fatty acid oxidation and mobilization, particularly in earlier sleepers. These effects might promote obesity if they recur chronically.", "pred_label": "__label__POS", "pred_score_pos": 0.9243631362915039}
{"content": "Global Trends Of Open Innovation\nThe\nTechStory website noted that the clear benefits of open innovation bring cost-effective methods in R&D with scope for improving productivity. Since priorities change, companies will start to seek for accurate market research targeting the right customers bringing about immense potential of productive synergies between internal and external innovation. World over, various models for open innovation include companies who work for their clients to secure ideas and technologies from the best innovators across the globe.\nClick here to read the full article.", "pred_label": "__label__POS", "pred_score_pos": 0.5134888291358948}
{"content": "The number of Americans seeking unemployment benefits in the wake of the coronavirus outbreak has doubled in just a week.\nAccording to Labor Department figures on Thursday, a record 6.6 million individuals filed for assistance, up from the revised 3.307 million that had been the previous record.\nThe jump is likely to cause the unemployment rate, currently at a nearly 50-year low of 3.5%, to soar when released on Friday, with some estimates reaching as high as 15%.\nMaking matters worse, this may not even be the complete picture, as many states' employment websites are overwhelmed and can't process all the claims.", "pred_label": "__label__POS", "pred_score_pos": 0.9684557914733887}
{"content": "PURIFICATION\nThe Sulfur Recovery Unit or Claus unit converts undesirable, toxic H2S gas into beneficial elemental sulfur. This process utilizes different types of Claus catalyst to facilitate the conversion.\nPURIFICATION\nPurification catalyst removes contaminants from liquid and gas processes using catalytic, regenerative, or sacrificial means. The catalyst is typically a mixed metal oxide formulated to remove specific contaminants. The catalyst can be in tabular or extrudate, or sphere shape.\nPURISTAR CATALYST\nPuristar R9-12/E-315- removes Os, CO, H2, etc Puristar Catalyst R3-12-removes arsine, phosphine, COS, H2S, etc Puristar Catalyst R3-15-removes O2, CO, H2, etc Puristar Catalyst R3-16-removes O2, CO, H2, sulfur, etc ProSorb-removes aresine, phosphine, sulfurs, O2, CO, CO2, H2 PuriStar R3-17-removes CO Puristar R3-81 -removes O2, NOx, etc Puristar R8-21 – removes O2, NOx, etc Puristar R3-11/R3-11G -Removes O2, CO, H2 HTZ-51 – removes sulfur compounds HTZ-31 – removes sulfur compounds SC-501 – removes H2S and other sulfurous compounds ST-201 – removes sulfur compounds LEADING WITH CATALYST SOLUTIONS\nContact Coastal Chemical to learn how we can assist with tabular, extrudate or sphere shaped catalyst.", "pred_label": "__label__POS", "pred_score_pos": 0.6568264961242676}
{"content": "Abstract : Purpose:\nDespite the urgency regarding increasing rates of obesity and chronic diseases in the Caribbean, few studies described the nutrition transition. We aimed to provide such information by identifying dietary patterns in the French West Indies and their characteristics.\nMethods:\nThis cross-sectional analysis included 1144 Guadeloupeans and Martinicans from a multistage sampling survey conducted on a representative sample. Dietary patterns were identified using principal component analysis followed by a clustering procedure, and described using multivariable regression models.\nResults:\nFour patterns were identified: (i) a “prudent” pattern characterized by high intakes of fruits, vegetables, legumes, seafood and yogurts, low intakes of fatty and sweet products, and a high Diet Quality Index-International (DQI-I); (ii) a “traditional” pattern characterized by high intakes of fruits, vegetables, tubers and fish, low intakes of red and processed meat, snacks, fast foods, and sweetened beverages, with a high DQI-I, mostly shaped by women and older persons; (iii) a “convenient” pattern characterized by high intakes of sweetened beverages, snacks, and fast foods, with the lowest DQI-I, principally shaped by young participants; (iv) a “transitioning” pattern characterized by high consumptions of bread, processed meat, sauces, alcoholic and sweetened beverages, but also high intakes of tubers, legumes, and fish, mainly shaped by men, middle aged, of whom 35% had metabolic syndrome.\nConclusion:\nThe co-existing dietary patterns in the French West Indies, marked by a generational contrast, seem to reflect different steps in dietary change as described in the literature, suggesting an ongoing nutrition transition.", "pred_label": "__label__POS", "pred_score_pos": 0.9749451279640198}
{"content": "Governments fight financial crime globally with new sanctions, including lists of states, entities, or individuals suspected of engaging in or being consistent with illegal activities.\nUN sanctions are diplomatic decisions enforced by the United Nations organizations and states against other states, entities, or individuals. These sanctions are measures of safety to preserve national safety interests, peace, and international law.\nThe international sanctions are generally special restrictions on cultural, economic, trading, and diplomatic relationships with a certain country designated individual or organization.\nIt is crucial to know if the client is subject to specific regulations or the corporation is coming from a sanctioned country. By knowing this information, institutions act accordingly and blocking them or applying needed restrictions to their interaction.\nBusinesses have to comply with these regulations. Otherwise, they will face harsh legal measurements, such as criminal and civil penalties.\nSanctions and the way of handling them are wide and depend on a reason or a specific case to applied regulations. Firms or individuals subjected to sanctions may be specific individuals prohibited from the UN, such as states or terrorists, meaning that their nationals have become influenced by restrictions like trade barriers or travel ban.\nUN sanctions are enforced by international authorities or the government result of the diplomatic policy or illegal activity. As the United Nations is the most powerful regulator of international peacekeeping, sanctions list are aimed to prevent terrorism, weapons proliferation, international treaties violation, money laundering, trafficking of narcotics, destabilization of sovereign countries, etc.\nSanctions can be:\nFor instance, the United Nations financial sanctions list includes countries like:\nFor these sanctioned countries, nationals being on the sanctioned list means that they may become subjects to travel prohibitions, commodity, or financial restrictions like not being allowed to have any conduct monetary transactions or do business with UN countries or specific regions.\nNowadays, having loads of clients and transactions, businesses can’t administrate to every case manually. It contains a huge amount of data, every single detail on each individual in question. That is the reason corporations have begun to apply screening software proving to be more effective and have accuracy over 99%.\nSanction Scanner’s database consists of over 1000 Sanctions, regulatory and law enforcement, and other official global and local sanction and pep lists, including those issued by the USA, UK, UN, and other global major and minor government departments. You can use integration between your Project and Sanction Scanner. This will automatically make your AML queries. We always keep our lists up to date. Sanction Scanner checks and processes updated Sanction and PEP lists every fifteen minutes. Sanction Scanner’s lists are compatible with all regional sanctions, CTF, and Anti-Money Laundering requirements. You will be using real-time data, always. AML Check is very easy with the Sanction Scanner.\nRequest a demo and learn how\nSanction Scanner protects your firm from the Financial Crimes.", "pred_label": "__label__POS", "pred_score_pos": 0.5917592644691467}
{"content": "A recent decision by the Delaware Supreme Court relating to a merger between two pharmaceutical companies that was terminated before closing could have implications on bank mergers and acquisitions.\nOn Dec. 7, 2018, the Delaware Supreme Court affirmed the lower court’s ruling in\nAkorn v. Fresenius Kabi that a Material Adverse Effect (“MAE”) had occurred with respect to Akorn under the terms of its merger agreement with Fresenius.\nThe Supreme Court upheld the lower court’s determination that (1)\nAkorn had suffered an MAE under the terms of the agreement that excused Fresenius from its obligation to close the transaction, and (2) Fresenius properly terminated the merger agreement because of Akorn’s breach of its regulatory representations and warranties under the merger agreement, which gave rise to an MAE, and Fresenius had not materially breached the merger agreement (which would have prevented it from exercising its termination rights).\nWhy the Akorn Case Is Important\nThis is the first ruling in Delaware that an MAE had occurred in a merger transaction, allowing the buyer to walk away from a signed merger agreement. The lower court’s opinion provides unprecedented guidance for future negotiation and litigation of MAE clauses. The decision is applicable to all industries, including the banking industry, and makes it clear that, first, the heavy burden to establish an MAE with respect to the target remains with the buyer.\nHow The Case Impacts Bank M&A\nMerger partners should carefully consider the categories of events or changes, as well as any specific events, that should be excluded from the MAE definition, ensuring that the definition accurately reflects the agreed upon allocation of risk between the parties. Sellers should exclude industry-wide changes impacting the seller, while buyers should be mindful to provide that broad industry changes that disproportionately affect the seller are not carved out from the definition. Typical carve-outs from the MAE definition in a bank merger agreement include: changes in laws and regulations affecting banks or thrift institutions, changes in GAAP, changes in the value of securities or loan portfolio or value of deposits or borrowings resulting from a change in interest rates, and changes relating to securities markets in general. Buyers who are uncomfortable with the broad definition of an MAE, even following Akorn, and are significantly larger than the seller may wish to consider inclusion of a few specific financial closing conditionsto supplement the broad MAE clause. Buyers in the bank M&A context should in good faith continue the regulatory approval process even while contemplating terminating the deal over a possible MAE — having “clean hands” matters. How the Court Found an MAE Fresenius, a German pharmaceutical company, and a U.S. generic drug manufacturer, Akorn, formally agreed in April 2017 to merge.\nShortly after, Akorn’s financial performance “fell off a cliff;” its revenues declined the next four quarters by 29 percent, 29 percent, 34 percent and 27 percent, respectively. Its operating income plummeted 84 percent, 89 percent, 292 percent and 134 percent, respectively, during the same period.\nFresenius terminated the merger agreement in April 2018, asserting that Akorn had suffered a general MAE. Fresenius further asserted it had an\nexplicit right to terminate the merger agreement because Akorn breached its regulatory compliance representations and warranties. Akorn’s lawsuit followed, seeking for the court to force Fresenius to close the transaction.\nThe Court of Chancery determined Akorn suffered a general MAE, which resulted from issues that disproportionately affected Akorn compared to similar companies in its industry. Focusing on the plain text of the merger agreement, the court determined that Akorn bore the general risk of the MAE and through several carve-outs to the provision, Fresenius bore the “systemic” risks related to Akorn’s industry. However, through specific exclusions from these carve-outs, the risk was shifted back to Akorn in the event that the risks disproportionately affected Akorn’s business as compared to other participants in its industry. In analyzing whether the effect was “material,”\nthe court stated the effect should “substantially threaten the overall earnings potential of the target in a durationally-significant manner.”\nIn other words, the court determined that Akorn’s dramatic downturn in performance was significant because it had persisted for a year and had no sign of abating, rejecting Akorn’s argument that any assessment of the decline in its value should be measured not against its performance as a standalone entity but against its value to Fresenius as a buyer.\nConclusion This case is directly applicable to the banking industry. Many banks suffered dramatic declines in earnings during the financial crisis that would be considered durationally significant within the framework reinforced by Akorn. Causes included massive credit losses, drastic margin compression and the regulatory reaction to the crisis. Banks need to take into account their risk profile and that of their merger partner when negotiating the MAE definition and consider how it would work under a variety of adverse economic environments.", "pred_label": "__label__POS", "pred_score_pos": 0.6965770721435547}
{"content": "Stratifying stroke risk to guide treatment in patients with non-valvular atrial fibrillation\nAntiplatelet (usually aspirin) and anticoagulant (usually warfarin) treatments are available to reduce the risk of stroke in patients with atrial fibrillation (AF) but both have potentially harmful adverse effects and warfarin can be time-consuming and expensive to monitor. Guidance exists for choosing between treatments but is often insufficiently detailed to support an informed choice about the risk and benefits. Prescribers and patients are often left with a choice between aspirin or warfarin, and aspirin – which is perceived to be safer and easy to use – is often chosen. This article explores the evidence for aspirin and warfarin in preventing stroke in patients with AF, and describes how we should change the way that decisions about treatment are made.", "pred_label": "__label__POS", "pred_score_pos": 0.9565262198448181}
{"content": "Schengen entry is free for citizens of 60 countries and no visa is required for stays up to 90 days for tourism purposes. However, the growth of visitors in Europe has raised security concerns and the European Commission has developed a mechanism for controlling the entry of Third-Country nationals into the Schengen Area to ensure greater security for nationals and residents – the European Travel Information and Authorization System (ETIAS).\nETIAS is intended for Third-Country nationals who are exempt from the visa requirement before traveling to the Schengen Area such as Brazil, Canada, USA, etc., and aims to implement a security and control system for their entry, being expectable to become operational by January 2021.\nThe application for the authorization will be made online and its approval should take a maximum of 4 days. It will cost € 7.00 for each citizen aged 18 years and over and is mandatory for any traveler who is allowed to enter without obtaining a visa, regardless of age.\nThis authorization will be valid for an unlimited number of entries into Schengen countries in the following 3 years after being issued or until the travel document registered during the application expires. However, the limit to stay in the Schengen Area is maintained – it cannot exceed 90 days within a period of 180 days.\nAir carriers and sea carriers will need to check before departure whether Third-Country nationals subject to the travel authorization requirement have a valid travel authorization or not. Three years after the entry into operation of ETIAS, this obligation will also apply to international carriers providing bus services.", "pred_label": "__label__POS", "pred_score_pos": 0.8313581943511963}
{"content": "Establishing a Cancer Registry in a Resource-Constrained Region: Process Experience From Ghana. Yarney J., Ohene Oti NO., Calys-Tagoe BNL., Gyasi RK., Agyeman Duah I., Akoto-Aidoo C., McGuire V., Hsing JC., Parkin M., Tettey Y., Hsing AW.\nPURPOSE: In a review of cancer incidence across continents (GLOBOCAN 2012), data sources from Ghana were classified as Frequencies, the lowest classification for inclusion, signifying the worst data quality for inclusion in the analysis. Recognizing this deficiency, the establishment of a population-based cancer registry was proposed as part of a broader cancer control plan. METHODS: The registry was examined under the following headings: policy, data source, and administrative structure; external support and training; and definition of geographic coverage. RESULTS: The registry was set up based on the Ghana policy document on the strategy for cancer control. The paradigm shift ensured subscription to one data collection software (CanReg 5) in the country. The current approach consists of trained registrars based in the registry who conduct active data abstraction at the departments and units of the hospital and pathologic services. To ensure good governance, an administrative structure was created, including an advisory board, a technical committee, and registry staff. External support for the establishment of the Accra Cancer Registry has come mainly from Stanford University and the African Cancer Registry Network, in collaboration with the University of Ghana. Unlike previous attempts, this registry has a well-defined population made up of nine municipal districts. CONCLUSION: The Accra Cancer Registry was established as a result of the lessons learned from failed previous attempts and aim to provide a model for setting up other cancer registries in Ghana. It will eventually be the focal point where all the national data can be collated.", "pred_label": "__label__POS", "pred_score_pos": 0.7747082710266113}
{"content": "The political landscape in the UK has shifted significantly in the last three months, but the future remains as uncertain as ever, especially in relation to Brexit. We continue to monitor the situation, and have further reduced our exposure to UK assets as a defensive measure.\nThe prospects for the addition and withdrawal of trade tariffs between the US and China, and others, have continued to move global markets, including weakening areas of the global economy in some regions too, significantly Europe, due to its heavy reliance on trade. However, we also see potential for more positive economic news in the near future as growth in the service industry may provide economic stability for countries that have previously relied on manufacturing.\nShould this deterioration persist we may have to prepare for a slowdown in economic growth. However it remains to be seen whether or not a recession will emerge.\nThroughout 2019, we have maintained a lower-than-average risk level in our Balanced, Conservative and Cautious portfolios. Despite this, they have outperformed their respective benchmarks, as we have been very selective in which risks we were willing to take. We hope to continue this trend by ensuring that our first priority is to preserve values by limiting the effects of market falls, even if this means we are likely to see more modest returns in the short term.\nRead the full detail here:", "pred_label": "__label__POS", "pred_score_pos": 0.9362870454788208}
{"content": "The PhD to Consulting (PtC) conference is a one day annual event targeted at doctoral and post-doctoral researchers interested in pursuing a career in consulting.\nA doctorate nurtures qualities like exceptional problem-solving skills, intellectual curiosity and a drive to achieve outstanding results. Commercial organisations and consulting firms are realising the potential of PhDs, valuing their fresh and thoughtful approach in delivering business insights. However, a number of high calibre researchers are unaware of this opportunity, and find it difficult to locate appropriate resources and guidance to realise a transition from academia to consulting.\nThe PtC conference provides a platform for discussion and networking for PhD researchers and professionals from top consulting firms. The conference will focus on topics such as:\nExploring how receptive the UK consulting industry is to PhD students/graduates. Determining the scope for PhD recruits in consulting. Defining the consulting industry expectations of PhD students/graduates. Outlining the skills that PhD recruit should have for a career in consulting and how they may apply. Establishing any sector/industry specific demands for PhD students/graduates. Analysing typical recruitment and assessment procedures, including case interviews and competencies.", "pred_label": "__label__POS", "pred_score_pos": 0.5956836938858032}
{"content": "According to the State Bank of Pakistan (SBP), Pakistan could expect GDP growth to stay within the range of 1.5–2.5% in FY21. The targeted GDP growth was 2.1%.\nThis growth is expected due to the steady performance of agriculture and the services sector.\nHowever, due to the second wave of coronavirus and some other factors, these growth projections are at risk:\nAs a result, while a rebound in growth is expected in nearly all the regions in 2021, downside risks remain high,Source\nThe SBP expected exports to stay in the range of $23.4–23.8 billion in FY21 – higher than the $22.5bn recorded in FY20.\nThe debt servicing relief of $2.7bn (equivalent to 1% of GDP) provided to Pakistan under the G-20’s Debt Servicing Suspension Initiative will help create expenditure space for Covid-19-related spending,\nThe SBP is expecting the inflation rate for FY21 to stay within the range of 7-9pc in FY21 against the target of 6.5%.", "pred_label": "__label__POS", "pred_score_pos": 0.9999672770500183}
{"content": "Fluid mechanics is governed by a set of equations called the Navier-Stokes equations, which are the mass conservation, momentum conservation as well as the energy conservation equations. These will be briefly discussed below but references such as the publications of Versteeg and Malalasekera [1] or Ferziger and Peric [2] present them in more detail and depth.\n1. Mass conservation\n\\underbrace{\\frac{\\partial \\rho}{\\partial t} }_\\mathrm{transitoire} + \\underbrace{\\vec{\\nabla} \\cdot (\\rho \\vec{v})}_\\mathrm{advection} = 0\nwhere \\rho is the fluid density and \\vec{v} the velocity vector.\nThis equation stipulates that if a fixed volume is considered within a studied domain, the mass of fluid entering the volume is equal to the mass of the outgoing fluid.\n2. Momentum conservation\n\\underbrace{\\frac{\\partial \\rho \\vec{v}}{\\partial t}}_\\mathrm{transitoire}+\\underbrace{ \\vec{\\nabla}\\cdot(\\rho\\vec{v}\\otimes\\vec{v})}_\\mathrm{advection}=\\underbrace{- \\vec{\\nabla} p + \\vec{\\nabla} \\cdot [\\tau]}_\\mathrm{diffusion} + \\underbrace{\\rho \\vec{g}}_\\mathrm{source}\nwhere p is the fluid pressure, \\vec{g} the gravity field and [\\tau] the tensor of viscous stresses.\nThis equation, derived from Newton's second law, governs the fluid movement. It establishes that the amount of movement is equal to the sum of the surface and volume forces acting on the fluid.\n3. Energy conservation\n\\underbrace{\\frac{\\partial \\rho h_{\\text{tot}}}{\\partial t} - \\frac{\\partial p}{\\partial t}}_\\mathrm{transitoire} + \\underbrace{ \\vec{\\nabla} \\cdot (\\rho \\vec{v} h_\\mathrm{tot})}_\\mathrm{advection} = \\underbrace{\\vec{\\nabla} \\cdot (\\lambda \\vec{\\nabla} T) + W_\\mu}_\\mathrm{diffusion} + \\underbrace{S_h}_\\mathrm{source}\nwhere h_{tot} is the enthalpy of the fluid, \\lambda the thermal conductivity and W_\\mu the thermal dissipation resulting from viscous stresses.\nThis equation, derived from the first principle of thermodynamics, ensures energy conservation within a fixed volume in space.\nThese three equations serve as a basis for contemporary fluid mechanics studies. Different versions of these equations can be used depending on the assumptions considered (incompressible fluids, Boussinesq approximation, etc.). Bernouilli's theorem, which is also commonly used, can be seen as an application of the momentum conservation to an incompressible, inviscid and stationary fluid. This can then be expressed with the following equation:\n\\frac{p}{\\rho}+\\frac{v^2}{2}+g z = \\mathrm{constante}\n4. References Versteeg, H. K., & Malalasekera, W. (2007). An introduction to computational fluid dynamics: the finite volume method. Pearson Education. Ferziger, J. H., & Peric, M. (2012). Computational methods for fluid dynamics. Springer Science & Business Media.", "pred_label": "__label__POS", "pred_score_pos": 0.9631422758102417}
{"content": "A Practical Guide to Addressing the Social Needs of Older Adults by West Health Institute and University of California, Irvine details how to implement a social needs screening and referral program for older patients into clinical practice. Driven by significant growth of the older adult population across the United States and the demand to improve health outcomes and reduce healthcare costs, there is heightened attention and increased awareness of the importance of social determinants of health. There is growing consensus that addressing not only the medical needs of an individual but also their social needs, is critical to achieve “whole-person care.” The screening and referral program that we share in this guide was developed and tested specifically for older adults in a clinical setting and considers key social needs that directly impact their daily function and ability to live independently. A Practical Guide to Addressing the Social Needs of Older Adults\nThis interactive guide provides an approach to address the social needs of older adult patients in four stages: ASSESS readiness, PREPARE teams and partners, IMPLEMENT the intervention, and EVALUATE the impact. The guide was developed based on insights from a collaboration between the Gary and Mary West Health Institute (WHI), the University of California, Irvine, Division of Geriatric Medicine and Gerontology, and SeniorServ, a large non-profit community-based organization in Orange County, CA.", "pred_label": "__label__POS", "pred_score_pos": 0.5254530310630798}
{"content": "<p>Bringing together leading scholars, scientists, and clinicians, this compelling volume explores how therapists can cultivate wisdom and compassion in themselves and their clients. Chapters describe how combining insights from ancient contemplative practices and modern research can enhance the treatment of anxiety, depression, trauma, substance abuse, suicidal behavior, couple conflict, and parenting stress. Seamlessly edited, the book features numerous practical exercises and rich clinical examples. It examines whether wisdom and compassion can be measured objectively, what they look like in t.</p>\nZotero Collections: Zotero Collections:\nWe have developed a low dose Mindfulness-Based Intervention (MBI-ld) that reduces the time committed to meetings and formal mindfulness practice, while conducting the sessions during the workday. This reduced the barriers commonly mentioned for non-participation in mindfulness programs. In a controlled randomized trial we studied university faculty and staff (n=186) who were found to have an elevated CRP level,>3.0 mg/ml, and who either had, or were at risk for cardiovascular disease. This study was designed to evaluate if MBI-ld could produce a greater decrease in CRP, IL-6 and cortisol than an active control group receiving a lifestyle education program when measured at the end of the 2 month interventions. We found that MBI-ld significantly enhanced mindfulness by 2-months and it was maintained for up to a year when compared to the education control. No significant changes were noted between interventions in cortisol, IL-6 levels or self-reported measures of perceived stress, depression and sleep quality at 2-months. Although not statistically significant (p=.08), the CRP level at 2-months was one mg/ml lower in the MBI-ld group than in the education control group, a change which may have clinical significance (Ridker et al., 2000; Wassel et al., 2010). A larger MBI-ld effect on CRP (as compared to control) occurred among participants who had a baseline BMI <30 (-2.67 mg/ml) than for those with BMI >30 (-0.18 mg/ml). We conclude that MBI-ld should be more fully investigated as a low-cost self-directed complementary strategy for decreasing inflammation, and it seems most promising for non-obese subjects.\nZotero Collections:\nPages", "pred_label": "__label__POS", "pred_score_pos": 0.9876375198364258}
{"content": "May 19, 2011 The recent crisis was characterized by widespread deterioration in funding conditions, as well as impairment of the mechanism through which liquidity is normally redistributed within the financial system. Central banks responded with extraordinary measures. This article examines the provision of liquidity by central banks during the crisis as they adapted their existing facilities and introduced new ones, while encouraging a return to private markets and mitigating moral hazard. A review of this experience illustrates the importance of clear principles for intervention, a flexible operating framework, and clear communication and co-operation by central banks. By exposing the degree of interdependence of financial institutions and markets, the crisis highlighted the need for reforms aimed at improving the infrastructure supporting core funding markets and the liquidity of individual institutions.", "pred_label": "__label__POS", "pred_score_pos": 0.9992622137069702}
{"content": "COVID-19 Preventative Measures To our valued customers and partners,\nThe BC Liquor Distribution Branch (LDB) is watching closely as the global situation with COVID-19 continues to evolve. I wanted to reach out to you personally to let you know what we’re doing to stem the spread of viral infections, including COVID-19.\nThe health and safety of our employees and customers is our highest priority\nOur highest priority continues to be the health and safety of our customers, employees and those in our supply chain network including wholesale customers, manufacturers, suppliers and delivery partners.\nWe are in regular contact with our team members across the organization to reinforce protocols that support everyone’s wellbeing. Each of our facilities, including Head Office, BC Cannabis Stores (BCCS) and our distribution centre are implementing more frequent processes for the cleaning and disinfecting of common areas and equipment.\nWe remain committed to delivering excellent customer service\nWe are working closely with our industry partners to mitigate potential supply issues, while reinforcing our safety and hygiene procedures. At this time, we are not experiencing any delays or impacts to the supply of non-medical cannabis product.\nWe are following the guidance of government and health authorities\nWe have activated our Emergency Operations Centre to monitor the situation and ensure our standards are being strictly adhered to. We are closely following the direction of our provincial health officials which maintain a low public health advisory for British Columbia at this time.\nWe have put processes in place to support prevention and are monitoring the health of our employees.\nWe will do everything we can to support provincial efforts to manage this virus, while continuing to provide service to British Columbians.\nBlain Lawson\nGM and CEO\nBC Liquor Distribution Branch", "pred_label": "__label__POS", "pred_score_pos": 0.6397734880447388}
{"content": "The Committee should ensure that any Local Rules are posted for players to see, whether on a separate handout on the first tee (sometimes referred to as a \"Notice to Players\"), the scorecard, a notice board or the course website.\nMany organizations that run multiple competitions create a document which contains all the Local Rules they commonly use in all of their competitions. Historically this document has been printed on card stock and is known as a \"Hard Card\".\nIf players are required to play balls on the Conforming Ball List (see Model Local Rule G-3) or use clubs on the List of Conforming Driver Heads (see Model Local Rule G-1) or that meet the groove and punch mark specifications (see Model Local Rule G-2), the Committee should consider making the lists available for players to view or provide access to the applicable online databases.\nSheets that provide the groupings for the round along with their starting times should be produced and posted in locations where players can check them. While players are frequently sent their pairings electronically or can check them on a website, they should also be available at the course so that players can reconfirm their starting time.\nThe Committee may wish to provide players with a sheet that shows them the position of the holes on the putting greens. These may be circles with the distance from the front of the green and the nearest side, a piece of paper with just the numbers or a more detailed set of drawings of the green and its surrounds with the location indicated.\nThe Committee is responsible for publishing on the scorecard or somewhere else that is visible (for example, near the first tee) the order of holes at which handicap strokes are to be given or received. This allocation will be used for handicap matches and in some forms of net-score stroke play such as Four-Ball, Stableford, Maximum Score (when the maximum score is linked to the player's net score) and Par/Bogey competitions. For guidance on how to determine the order, consult the rules or recommendations contained within the Handicap System operating in the local jurisdiction.\nMatch Play - In a handicap match, the Committee should clarify the following in the Terms of the Competition:\nWhere the Committee has authorized a match to begin at a hole other than the 1st, the Committee may alter the stroke index allocation table for such matches.\nStroke Play - In a net-score competition, the Committee should determine the handicap allowances in accordance with the rules or recommendations contained within the Handicap System operating in the local jurisdiction. For example, if full handicap, or a percentage of the handicap, will be applied.\nCopies of the Pace of Play and Code of Conduct policies should be available to players before the competition begins. When players are unfamiliar with these policies, the Committee may wish to go over them with the players in advance of the competition.\nReferees and others who will be enforcing these policies should be trained and provided with any other additional materials, such as timing sheets or scripts with the specific language they should use to inform players of warnings or possible breaches.\nEach Committee should consider how to evacuate players in case of severe weather or another emergency. If it is felt necessary, an evacuation plan may be created and provided to the players. Additional information can be found in Model Local Rule J-1.", "pred_label": "__label__POS", "pred_score_pos": 0.7389991283416748}
{"content": "When your spouse breaks their promise to remain faithful to you for the duration of your marriage, that could very well lead to divorce. If you have recently filed for divorce from your spouse in Texas, you may wonder whether that adultery will have any bearing on the case.\nUnlike most states, which have rules that specifically prevent the courts from considering marital misconduct when splitting up a couple’s assets, Texas does allow the consideration of verifiable adultery to influence the division of your assets and debts. That means that if you can prove adultery, there may be financial consequences for your tax and financial benefits for you.\nHowever, the situation can quickly become more complicated if your spouse is an active member of the military.\nMilitary rules are very clear about adultery\nThose who serve in the military must comply both with civilian laws and the Uniform Code of Military Justice (UCMJ). The rules in the UCMJ go over everything from how someone should behave while in uniform to their obligations to the society around them. Part of those obligations involves being an upstanding member of society, which does not typically involve adultery.\nMilitary members who commit adultery while in the service could very well face court-martial as a result. The military has adjusted its definition of adultery to now include more than just procreative sex between opposite-sex partners. Additionally, there are now rules that offer some leniency for those who begin dating during a separation but prior to a formal divorce.\nIf you leverage your spouse’s adultery, that could affect their military career, and therefore, any benefits that you might hope to receive as a result of your support of them during their service. Discussing the potential impact of adultery claims on your divorce with an attorney before you file can help you make the best decision for your situation.", "pred_label": "__label__POS", "pred_score_pos": 0.6009101867675781}
{"content": "Niestety wyniki u szczurow ale zawsze cos\nNa dole podsumowanie najwzniejszych spraw:\nOptimal and effective oral dose of taurine to prolong exercise performance in rat.\nMiyazaki T, Matsuzaki Y, Ikegami T, Miyakawa S, Doy M, Tanaka N, Bouscarel B.\nIbaraki Prefectural Institute of Public Health, Mito, Japan.\nThe aim of this study was to determine the effective and optimum dose of taurine for exercise performance and to maintain tissue taurine concentration. Rats received a respective daily dose of 0, 20, 100, and 500 mg/kg body weight of taurine (EC and ET-1, -2, -3 groups, respectively) for two weeks, and then, were subjected to treadmill until exhaustion. The running time to exhaustion was significantly prolonged by 25% and 50% in the ET-2 and -3 groups, respectively, compared to that in the EC group accompanied with maintenance of taurine tissue concentrations. Furthermore, the oxidative glutathione per total glutathione ratio in tissues was inhibited in the ET-2 and -3 groups whereas it was higher in the EC group than in both the no exercise and taurine-administered groups. Therefore the effective and optimal doses of oral taurine administration for two weeks on a transient exercise performance were between 100 and 500 mg/kg/day.\nU szczurow o ktorych podano 100 mg/kg 25% wzrosl czas biegu do wyczerpania\nU szczurow o ktorych podano 500 mg/kg 50% wzrosl czas biegu do wyczerpania\nZmieniony przez - bimbam w dniu 2005-04-26 09:06:40", "pred_label": "__label__POS", "pred_score_pos": 0.7481327056884766}
{"content": "Pathogenic or benign. In 2018, ICK, coding for Intestinal-Cell Kinase, was reported as a novel causative gene in Juvenile Myoclonic Epilepsy (JME) in the New England Journal of Medicine. JME is one of the most common epilepsy syndromes, and the authors suggested that up to 7% of JME in their study may be explained by pathogenic variants in this gene, suggesting that, if applicable to all individuals with JME, it may provide a genetic diagnosis for an expected 500,000 individuals worldwide. In a reply to the initial study, the investigators of the EuroEPINOMICS-CoGIE, EpiPGX, Epi4K, and EPGP Consortia attempted to replicate these initial findings, but could not find any evidence in for a role of ICK in JME and indicated that the initial results may have arisen by chance and due to methodological issues. Given the potential implications for future research and therapy development in a relatively common epilepsy, the controversial ICK story is a good example to highlight why it is important to revisit the current consensus on when we consider a candidate a true disease gene and why a category mistake confusing variant pathogenicity for gene validity may result in false positive findings. Epilepsy genes. Let me preface this blog post by the statement that I am not neutral, as I am both a member of the EuroEPINOMICS consortium, authoring the letter to the NEJM editor and a member of the ClinGen Epilepsy Gene Curation Expert Panel, which is tasked with evaluating gene-disease relationships in the epilepsies. As of April 2019, we have not yet formally reviewed the evidence for or against ICK, so this blog post is not written in my role as the ClinGen Epilepsy Expert Panel leader. In addition, rather than taking sides in the discussion regarding ICK, I would like to lay out the general framework for when we call a gene a valid “epilepsy gene”, assessing a concept referred to as gene validity. Gene validity versus variant pathogenicity. There are two major concepts that we discussed in our 2018 Primer of the Genetic Literacy Series: clinical validity of the disease-gene relationship and variant pathogenicity. Clinical validity of the disease-gene relationship asks whether there is sufficient evidence that support the role of pathogenic variants in a gene in a given disease. Variant pathogenicity assesses the evidence for a particular variant to be disease-causing. For example, a truncating variant in SCN1A in an individual with Dravet Syndrome is pathogenic as the gene is a valid disease gene for Dravet Syndrome (i.e. the clinical validity of the disease-gene relationship of SCN1A and Dravet syndrome is established) and haploinsufficiency is an established disease mechanism with absence of protein-truncating variants in the general population (variant pathogenicity: check). However, variant pathogenicity is irrelevant if the disease-gene relationship is not clinically valid. For example, you may find a de novo truncating variant in the Mucin 12 gene ( MUC12) in an individual with Dravet Syndrome that has similar variant properties. However, as MUC12 is not a disease gene, this variant is not disease causing. In fact, MUC12 is a rather variable gene in the human genome with more protein-truncating variants than you would expect. Taken together, the validity of the disease-gene relationship must be established before assessing whether a given variant can be disease causing. The ICK gene. In their 2018 publication, Bailey and collaborators initially identified an ICKc.914A>C (p.K305T) missense variant in a large family with JME including 12 affected individuals. The variant segregated within this family. They subsequently identified further missense variants in 22 of 310 additional patients from the GENESS consortium that has study sites in United States, Mexico, Honduras, Brazil, and Japan. While JME is a relatively mild phenotype, disease-causing variants are typically not found in unaffected individuals. However, the ICKc.914A>C (p.K305T) missense variant is found in allegedly unaffected Latino individuals in the gnomAD browser (Figure 1). While it is theoretically possible that such a scenario occurs, such a variant would usually not be considered disease-causing unless there is further evidence for this particular variant. A similar situation is encountered with the PRRT2gene, where the common disease-causing c.649dupC variant is encountered in single individuals in large population databases (link), but the genetic evidence for this particular variant is overwhelming and confirmed over time. This is conceptually different from the ICKc.914A>C (p.K305T) variant. Accordingly, even a low population frequency is typically a strike against a variant being disease-causing and suggests that the ICKc.914A>C (p.K305T) variant is a population variant. If this variant that is seen in 1:5000 individuals were a true disease variant, it alone would account for 20% of all JME. Basically, genetic variation has been recognized as so prevalent that genes have fight an “uphill battle” to convince us that they are disease causing. This evidence needs to occur primarily on a genetic level, e.g. functional data cannot compensate for the lack of genetic evidence. If we hypothesize that ICK in the general population. ICKvariants are disease-causing through a loss-of-function mechanism, we would typically expect protein-truncating variants to be very rare or absent in the general population, a measure that is quantified by the probability of being loss-of-function intolerant (pLI) score that is implemented in the gnomAD browser. Genes such as SCN1Aor STXBP1have a pLI of 1.00, suggesting that loss-of-function variation is not tolerated in the general population. In other words, there is significant gene constraint. For ICK, the situation is different (Figure 1). The ICKgene is not constrained in the general population. Validation. While is it possible that ICK only causes disease due to a low frequency population variant in a single family, such an isolated phenomenon usually would not account for sufficient gene validity and independent validation is required. This is what has been attempted in the joint EuroEPINOMICS-CoGIE, EpiPGX, Epi4K, and EPGP letter to the NEJM editor, which was not able to validate the initial results. While negative results do not “harm” the status of ICK as a rare disease gene in a single family, it demonstrates that this finding is not generally applicable. Where does this leave us with regards to evaluating the role of ICK in JME? Population genetics argues against haploinsufficiency as the disease mechanism and suggested pathogenic variant in the initial family is a rare Latino population variant. While there is significant genetic heterogeneity in the epilepsies that would allow for such a scenario to occur for true disease-causing variant, it is highly unusual in 2019 for a true gene-disease association to fail replication given the range of resources available. Past experience has shown that the alleged disease variants turned out to be benign population variants.", "pred_label": "__label__POS", "pred_score_pos": 0.7657480239868164}
{"content": "The test methods described are designed to determine the disinfectant activity of processes used in the 1) medical area, 2) veterinary area, 3) food, industrial, domestic and institutional area using automated processes for distributing chemicals by air diffusion with no operator manually applying the disinfectant. This document covers the disinfection of nonporous surfaces but not that of the air.\nThe objective of the described processes is to disinfect the surfaces of the overall area including the external surfaces of the equipment contained in such rooms. Air handling and products or processes specifically designed for the disinfection of medical devices are excluded from the scope of this document. The test methods and volumes described provide a defined challenge. This document is applicable to processes for which activity is claimed against the following groups of microorganisms: - vegetative bacteria, - mycobacteria, - bacterial spores, - yeasts, - fungal spores, - viruses, - bacteriophages. This document does not cover processes for which the mode of action is based on immersing and/or circulation, flooding, spraying, wiping or other processes where the product is directly applied to the surfaces and not via air dispersion.\nOznačení ČSN EN 17272 (665231) Katalogové číslo 510515 Cena 570 Kč570 Datum schválení 1. 10. 2020 Datum účinnosti 1. 11. 2020 Jazyk angličtina (obsahuje pouze anglický originál) Počet stran 68 stran formátu A4 EAN kód 8596135105151 Dostupnost skladem (tisk na počkání)", "pred_label": "__label__POS", "pred_score_pos": 0.9670030474662781}
{"content": "A strong case can be made that the fundamental supports of the housing market– demographics, employment, creditworthiness and income–will not recover for a generation. – Of Two minds\nBy Charles Hugh Smith at Of Two Minds\nEXCERPTS:\nIt can even be argued that housing has lost its status as the foundation of middle class wealth, not for a generation, but for the long term.\nRising rates of homeownership require five conditions:\n1. Favorable demographics: a cohort of potential buyers that is larger than the cohort of potential sellers.\n2. Rising household formation rates: an expanding population does not necessarily translate into rising rates of household formation. If the number of people per household goes up, then the number of households can plummet even as population expands.\n3. A large cohort of creditworthy potential buyers: that means buyers with savings, buyers with sufficient income to pay the mortgage and buyers with low debt loads.\n4. An economy that generates rising incomes to support homeownership.\n5. An unshakable belief that owning a house is a favorable and secure investment that will rise in value in the decades ahead.\nIf the first four conditions have eroded, then the belief in the permanence of a rising housing market will also erode.\nHelp Make A Difference By Sharing These Articles On Facebook, Twitter And Elsewhere:", "pred_label": "__label__POS", "pred_score_pos": 0.7356246709823608}
{"content": "How to Write a Rebuttal Letter to Your Employer for Being Passed Over for a Promotion\nNot getting the promotion you wanted can be devastating, especially if you believed your qualifications were better than those of other candidates. Once you've had time to think about the promotion and perhaps ask why you didn't get the job, writing a rebuttal letter might not get you the job but it could position you for consideration when future promotional opportunities arise. Don't write an emotionally driven letter to argue why you should have received the promotion. Write a rebuttal letter with a professional tone that clearly and rationally explains your point.\nValidate\nReview the skills, qualifications and expertise required for the promotion you wanted. Obtain the materials your human resources department or the hiring manager had to determine if you were eligible for a promotion. Compare those materials to your resume to see if the qualifications they had to go by in the selection process match your qualifications. Note any areas where your qualifications and skills exceed those required for the promotion.\nChronology\nDraft a chronology of your history with the company. Include your positions and a brief statement about your job duties, as well as promotions and raises you received during your employment. Describe instances where you've assumed higher-level responsibilities in the absence of your supervisor or manager. If you've performed the duties required in the job that you didn't get, explain when and how often you performed those duties and accolades you received for your performance.\nApplication\nTrace your steps through the application process for the promotion. If there wasn't a formal process, describe how you expressed an interest in the promotion during conversations with your boss or someone from the HR department. Include statements made to you that indicated you might have been in the running for the promotion, such as acknowledgement for receipt of your formal application for the job.\nJustification\nState why you were entitled to the promotion. Refrain from comparing yourself to the person who received the promotion -- base your rebuttal letter on the merits of your qualification, not how you are a better candidate than a colleague who was promoted. If your employer recruited external candidates for the job and ultimately hired someone from the outside to fill the position, explain why you would have been a more suitable person for the job. In this case, describe how your knowledge of the company's mission and philosophy, as well as existing relationships with employees, make selecting an internal candidate a wise decision instead of hiring from outside the organization.\nInterest\nExpress your regret for not receiving the promotion. Reiterate your continued interest in being promoted. Restate your strengths and include an updated version of your resume to ensure HR or the hiring manager has a current record of your skills and qualifications. Ask for guidance, training or professional development opportunities to prepare you for a future promotion.\nReferences\nWriter Bio\nRuth Mayhew has been writing since the mid-1980s, and she has been an HR subject matter expert since 1995. Her work appears in \"The Multi-Generational Workforce in the Health Care Industry,\" and she has been cited in numerous publications, including journals and textbooks that focus on human resources management practices. She holds a Master of Arts in sociology from the University of Missouri-Kansas City. Ruth resides in the nation's capital, Washington, D.C.", "pred_label": "__label__POS", "pred_score_pos": 0.925958514213562}
{"content": "In Tennessee and most states, you are considered \"per se\" under the influence for driving if your blood-alcohol content is measured at 0.08%. However, the National Transportation Safety Board has issued a recommendation encouraging all states to lower their per se standards to 0.05%. In 2018, the state of Utah became the first to do so.\nNow, New York state is considering doing the same thing. Two members of the state assembly have introduced a bill to lower the per se standard to 0.05% and also to lower the threshold for another New York law, aggravated driving while intoxicated, from .12%-.18%.\n\"This bill is about bringing loved ones home safely,\" one of the assemblymen told reporters. \"Reducing the BAC limit from .08 to .05 in New York will save lives. It's common sense legislation.\"\nAccording to a memo accompanying the bill, some 10,000 people are killed each year in crashes involving impaired drivers. Another 173,000 or more are injured.\nWould reducing the BAC standard bring down drunk driving accidents?\nThat is unclear. What seems clearer is that lowering the threshold would expose many more people to arrest for DUI. After all, it only takes about three to four drinks for the average person to reach the 0.08% threshold. If we lowered the threshold to 0.05%, people who had previously been considered sober enough to drive would then be considered dangerously drunk.\nWhat we need is some agreement, and ideally scientific consensus, on when a person is truly impaired. That is difficult to come by, especially because different people metabolize alcohol at somewhat different rates.\nMen become less intoxicated per drink than women, and larger people can generally drink more before becoming intoxicated. Conversely, smaller people and those with certain medical conditions can become more intoxicated than average after a few drinks. Therefore, one person might be impaired after three drinks while another might not be.\nAre the police hampered by the 0.08% standard? Are they failing to arrest obviously intoxicated drivers because they test at or below 0.08%? They have the authority to arrest anyone who, in their professional opinion, is too impaired to drive.\nThe American Beverage Institute, a trade group representing the hospitality industry, argues that 0.05% is just too low. \"The move is an attack on the restaurant and hospitality industries,\" it says, \"and converts their responsible customers into criminals.\"\nWe can't have a per se DUI standard that responsible drinkers would fail.", "pred_label": "__label__POS", "pred_score_pos": 0.7707447409629822}
{"content": "This article examines delayed onset Post Traumatic Stress Disorder (PTSD) among UK military personnel.\nAbstract\nDelayed-onset posttraumatic stress disorder (PTSD) is defined as onset at least 6 months after a traumatic event. This study investigates the prevalence of delayed-onset PTSD in 1397 participants from a two-phase prospective cohort study of UK military personnel. Delayed-onset PTSD was categorized as participants who did not meet the criteria for probable PTSD (assessed using the PTSD Checklist Civilian version) at phase 1 but met the criteria by phase 2. Of the participants, 3.5% met the criteria for delayed-onset PTSD. Subthreshold PTSD, common mental disorder (CMD), poor/fair self-reported health, and multiple physical symptoms at phase 1 and the onset of alcohol misuse or CMD between phases 1 and 2 were associated with delayed-onset PTSD. Delayed-onset PTSD exists in this UK military sample. Military personnel who developed delayed-onset PTSD were more likely to have psychological ill-health at an earlier assessment, and clinicians should be aware of the potential comorbidity in these individuals, including alcohol misuse. Leaving the military or experiencing relationship breakdown was not associated.\nFull Reference\nGoodwin, L; Jones, M; Rona, RJ; Sundin, J; Wessely, S; Fear, NT 2012. Prevalence of Delayed-Onset Posttraumatic Stress Disorder in Military Personnel: Is There Evidence for This Disorder? J Nerv Ment Dis;200: 429Y437", "pred_label": "__label__POS", "pred_score_pos": 0.858745813369751}
{"content": "City making in the Global South has been notoriously characterized for its simultaneous, although differing modes of operation: a formally planned and legal one that meets the needs and buying power of the wealthier part of the population, and an unplanned, illegal one, caused by the unmet demand of the remaining part. As a result, self-built homes and spontaneous settlements have emerged, and represent a large portion of the built environment, albeit a very compromised and unequal one.\nFor several decades, cities in Latin America have made significant investments to reverse this trend. However, improvement efforts alone have not been enough to lift the negative stigma from these territories. Recognition of\nbarrios, villas and favelas as parts of the city is a task still pending.\nIn a critical review of upgrading interventions, the presence of public space emerges as a key transformative element. The publication argues to expand the agency of architects and urban designers and creatively find ways of justifying, financing, and building public spaces in communities – spaces that have a catalytic effectiveness in achieving significant urban and social transformation.\nThis publication was made possible by the Graham Foundation and CAF, development bank of Latin America, as well as the Wheelright Fellowship from Harvard University.\nThe book was edited and published by Actar Publishers.", "pred_label": "__label__POS", "pred_score_pos": 0.7284523248672485}
{"content": "We present a combined theoretical and experimental effort to enable strong light absorption (>70%) in atomically thin MoS2 films (<= 4 layers) for either narrowband incidence with arbitrarily prespecified wavelengths or broadband incidence like solar radiation. This is achieved by integrating the films with resonant photonic structures that are deterministically designed using a unique reverse design approach based on leaky mode coupling. The design starts with identifying the properties of leaky modes necessary for the targeted strong absorption, followed by searching for the geometrical features of nanostructures to support the desired modes. This process is very intuitive and only involves a minimal amount of computation, thanks to the straightforward correlations between optical functionality and leaky modes as well as between leaky modes and the geometrical feature of nanostructures. The result may provide useful guidance for the development of high-performance atomic-scale photonic devices, such as solar cells, modulators, photodetectors, and photocatalysts.", "pred_label": "__label__POS", "pred_score_pos": 0.9845006465911865}
{"content": "When a business owner or new homeowner purchases a piece of real estate, they may be surprised to find that someone else is permitted by law to be on their property for a specific purpose. This right is known as an easement. Easements in California can be established in four different ways.\nOne way to establish an easement in California is through an express grant. Express easements are those where the landowner actually gives an easement to someone else. This can be done through a deed, contract or other written document.\nAnother way to establish an easement in California is through implication. Implied easements are created when a piece of land is split into two or more part, but it is intended by both owners that the owner of one part of the land is permitted to enter the other part of the land for a specific purpose. However, such easements only exist if there is a strict necessity for them. Strict necessity exists when no other convenient way to access the property is available. However, in contrast to express easements, implied easements do not have to be written.\nA third way to establish an easement in California is through necessity. These are similar to implied easements. However, while implied easements may exist out of convenience, an easement by necessity exists when no alternative access to one part of the property is available at all.\nFinally, easements in California can be established by prescription. This takes place when a person has openly, notoriously and continuously for at least five years been using the easement. The person using the easement must be doing so without the landowner’s permission. Easements by prescription need not be in writing.\nUltimately, if you purchased a piece of property that has an easement on it or if you believe you have a right to an existing easement on another’s property, it is important to seek legal advice. Easements are legal constructs, and this post cannot promise any specific result with regards to easement issues. Attorneys in California may be a useful resource to those with questions about easements.", "pred_label": "__label__POS", "pred_score_pos": 0.9800822734832764}
{"content": "Adding a few healthy habits to your daily routine will do wonders for your long-term health. These tips may even boost longevity!\nThis herbal kit contains botanicals that are rich in antioxidants and nutrients intended to support healthy immune function. The herbal supplements can assist your body with protecting itself from external threats.", "pred_label": "__label__POS", "pred_score_pos": 0.9902732372283936}
{"content": "Learning how to manage performance well has significant benefits for both the employee and the organisation.\nWhen underperformance is managed fairly and positively, employee loyalty and motivation improves. When working at its best it takes an employee who would be excellent but for one or two performance weaknesses and enables them to live up to their potential. This improves their long-term job security and workplace productivity.\nManagement of performance should not be a huge event; it should be quick and relatively pain free and something that’s done incrementally at the first sign of a deviation in ‘expected’ behaviour. If unaddressed for long periods of time it can become a major problem.\nThis course provides the ‘how to’ of effectively identifying and addressing underperformance. The focus is on helping employees to achieve their potential.\n– Understand what drives performance\n– Recognise underperformance – Identify the causes of underperformance – Effectively address underperformance – Support employees to achieve their full potential – Enhance employee engagement and loyalty – Develop performance objectives and motivate commitment – Determine when to apply informal and formal performance counselling – Develop a Performance Improvement Plan.", "pred_label": "__label__POS", "pred_score_pos": 0.8914401531219482}
{"content": "This week’s must reads in patient safety and health care focus on the need for supporting and maintaining a culture of safety. Two items may be overlooked as the emphasis is placed (where it should) on preventing adverse events and death to the patient:\nSupport the “second victim”. Celebrate patient safety efforts.\nThe concept of safety culture originated outside health care, in studies of high reliability organizations, organizations that consistently minimize adverse events despite carrying out intrinsically complex and hazardous work. High reliability organizations maintain a commitment to safety at all levels, from frontline providers to managers and executives. This commitment establishes a “culture of safety” that encompasses these key features: acknowledgment of the high-risk nature of an organization’s activities and the determination to achieve consistently safe operations a blame-free environment where individuals are able to report errors or near misses without fear of reprimand or punishment encouragement of collaboration across ranks and disciplines to seek solutions to patient safety problems organizational commitment of resources to address safety concerns Support the “Second Victim ”\nIn a recent post, Cheryl Connors, RN, MS (Patient Safety Specialist, Armstrong Institute for Patient Safety and Quality) reminds us to support the “second victim” and provide emotional first aid:\nSupporting the “second victim” supports a #patientsafety culture #healthcare Click To Tweet\nLet’s say that you’re a nurse on a hospital unit, and a colleague has recently been involved in a medication error. It was a mistake that anyone might make — a tenfold overdose that occurred when she wrote down an order and accidentally moved a decimal point one space to the right. Luckily, it didn’t lead to major harm, but the nurse is visibly shaken by the event and the investigation that followed. She looks to you for help dealing with her feelings of professional inadequacy and fear.Now the pressure is on you. What do you say? What words should you avoid? Celebrate P atient Safety Efforts\nRaema A. Howell, MSHI, BSN, RN, CNOR discusses another important element in creating a patient safe culture – celebrating success:\nCelebrating safe #medical procedures supports a #patientsafety culture #healthcare Click To Tweet\nKeeping patients safe is a challenging goal shared by all health care providers. In the perioperative setting, care providers ’ actions are guided by providing a safe experience for patients. A successful surgical outcome occurs because of perioperative nurses and other team members whose expertise and knowledge helps protect patients from harm. Surgeries that occur without incidents or near misses should be acknowledged and the team members should be recognized for excellence.", "pred_label": "__label__POS", "pred_score_pos": 0.5257915258407593}
{"content": "A study conducted at Florida Atlantic University found that mice who were taken from the cage they lived in and later placed back in it caused a surge of dopamine \"that mimics the response to a dose of cocaine.\"\nFrom Science Daily:\nThe researchers questioned whether their findings reflected leaving an unappealing environment or if it truly was a response to the positive aspects of a known and safe environment. Therefore, they examined whether dopamine surges arise when the mice were relocated from the plexiglass recording chamber to a clean cage with natural bedding matching the one they had been living in prior to the study. Indeed, dopamine release occurred, however, this release was not as large as that observed when mice were transferred to the home cage and the dopamine surge was not as sustained.\n\"We weren't really exploring home cage effects,\" said Felix Mayer, Ph.D., a post-doctoral fellow in Blakely's lab and lead author of the study. \"However, we were struck as to how reliable the manipulation was in evoking dopamine release particularly when placed in the context of little or no rise in dopamine when the mice were moved from the home cage to the test chamber. We are excited now to see if the genetic models of brain disorders we study will impact this effect.\"", "pred_label": "__label__POS", "pred_score_pos": 0.6379839181900024}
{"content": "Abstract\nA correlative study in 50 cases of healed myocardial infarction compared the 12 lead electrocardiogram with pathologic observations. The electrocardiogram was interpreted according to established Minnesota codes with some modifications. The following conclusions were reached: (1) The electrocardiogram underestimates the extent of myocardial infarction. (2) When a healed myocardial infarct at a specific location is recognized with electrocardiographic criteria, it is likely that there are unrecognized infarcts involving other areas of the left ventricle. (3) Infarctions involving the lateral and inferobasal areas are frequently unrecognized. (4) The electrocardiogram is more likely to miss myocardial infarcts in patients with multiple, than in those with single, electrocardiographically diagnosed infarcts. (5) Apical myocardial infarction does not appear to have specific electrocardiographic findings, other than those related to general infarct localization by electrocardiogram, particularly in patients with anteroseptal or anterolateral infarction. (6) Abnormal Q waves, generally thought to indicate transmural myocardial infarction, are frequently found in subendocardial infarction. (7) The simplified electrocardiographic classification of myocardial infarct site (anteroseptal, inferior, anterolateral) used in this study is preferable to more detailed classifications previously suggested by others.", "pred_label": "__label__POS", "pred_score_pos": 0.5859248638153076}
{"content": "Abstract\nIn seeking to support diversity, one challenge lies in adequately supporting and assessing science cognitions in a writing-intensive Biochemistry laboratory course when highly engaged Asian English language learners (Asian ELLs) struggle to communicate and make novice errors in English. Because they may understand advanced science concepts, but are not being adequately assessed for their deeper scientific understanding, we sought and examined interventions. We hypothesized that inquiry strategies, scaffolded learning through peer evaluation, and individualized tools that build writing communication skills would increase confidence. To assess scientific thinking, Linguistic Inquiry Word Count (LIWC) software measured underlying analytic and cognitive features of writing despite grammatical errors. To determine whether interventions improved student experience or learning outcomes, we investigated a cross-sectional sample of cases within experimental groups (n = 19) using a mixed-methods approach. Overall trends of paired t-tests from Asian ELLs’ pre/post surveys showed gains in six measures of writing confidence, with some statistically significant gains in confidence in writing skill (p=0.025) and in theory (p≤0.05). LIWC scores for Asian ELL and native-English-speaking students were comparable except for increased cognitive scores for Asian ELLs and detectable individual differences. An increase in Asian ELLs’ cognitive scores in spring/summer over fall was observed (p = 0.04), likely as a result of greater cognitive processes with language use, inquiry-related interventions, and peer evaluation. Individual cases further elucidated challenges faced by Asian ELL students. LIWC scores of student writing may be useful in determining underlying understanding. Interventions designed to provide support and strengthen the writing of Asian ELL students may also improve their confidence in writing, even if improvement is gradual.\nPubMed: MeSH publication types Journal Article", "pred_label": "__label__POS", "pred_score_pos": 0.5117015838623047}
{"content": "Abstract\nWe have recently demonstrated that anionic liposomes efficiently introduce foreign DNA into postmitotic neurons and other cell types (Lakkaraju, A., Dubinsky, J. M., Low, W. C., and Rahman, Y.-E. (2001) J. Biol. Chem. 276, 32000-32007). To investigate the mechanism of liposome uptake, we followed the internalization of anionic liposome-encapsulated Cy3-1a-beled oligonucleotides (AL-Cy3ONs) by hippocampal neurons using confocal microscopy. Uptake of AL-Cy3ONs was widespread and time- and temperature-dependent, indicative of receptor-mediated endocytosis. The low-density lipoprotein receptor-related protein (LRP) was crucial for anionic liposome endocytosis because the receptor-associated protein or an anti-LRP antibody inhibited internalization, and fibroblasts lacking LRP did not internalize AL-Cy3ONs. Using selective endocytosis inhibitors, we found that liposome endocytosis and intracellular transport required clathrin, dynamin, an intact cytoskeletal network, and phosphatidylinositol 3-kinase activity. Cy3ONs did not significantly colocalize with recycling endosomal/lysosomal markers and entered neuronal nuclei within 1-3 h of incubation. Approximately 50% of the internalized liposomal phospholipids were recycled back to the cell surface, in keeping with the fluidity of their acyl chains. Liposome endocytosis did not require heparan sulfate proteoglycans or cause calcium influx into neurons. Thus, constitutive endocytosis of anionic liposomes by LRP utilizes only one component, in contrast to the more involved heparan sulfate proteoglycan-LRP pathway implicated in the pathogenesis of Alzheimer's disease.", "pred_label": "__label__POS", "pred_score_pos": 0.625807523727417}
{"content": "Phobias Definition\nThe term\nphobia is derived from the Greek language elements phobos (irrational fear, terror, panic) and phobien (\"to put to flight\"). Types of Phobias Simple Phobias / Specific Phobias\nSimple phobias are irrational, ongoing fears coupled with compelling desires to avoid certain situations or things. Because these fears are connected a particular object or circumstance, they are also known as specific phobias. Many common phobias fit into this category:\nFears around transportation, like the fear of flying or traveling across bridges Animal phobias, such as the fear of snakes Medical fears, i.e. white coat syndrome, the fear of doctors or fear of needles Other specific phobias like the fear of clowns Social Phobias\nPer the name, these phobias are connected to social situations. In some cases, a fear of impending danger is at the heart of the fear, such as fearing being in a crowd. In other cases, a person may fear being watched or judged, as in the common fear of public speaking.\nObsessive Phobias\nThese phobias are marked by fears not rational given the situation, are unexplainable by the affected individual and beyond voluntary control. These phobias often coincide with correlated obsessive compulsive disorders.\nPhobia Causes and Treatment\nIn most cases, the person experiencing a phobia has had some measure of a negative experience with the event or thing serving as the object of the fear.\nThis experience could have happened recently or earlier in childhood.\nOften, the media and popular culture will reinforce phobias. The fears of snakes, flying and public speaking are examples of common phobias that have been depicted on TV, in movies and in the news.\nTreatment often begins with identifying the root cause of phobias. Adapting a more realistic mindset of the fear, along with systematic desensitization are also common treatment strategies. Professional help in the form of therapy is also a time-honored treatment modality.", "pred_label": "__label__POS", "pred_score_pos": 0.8226656913757324}
{"content": "Abstract\nArginine deprivation is a promising strategy for treating ASS-negative malignant tumors including melanoma. However, autophagy can potentially counteract the effectiveness of this treatment by acting as a pro-survival pathway. By combining tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) with arginine deprivation using ADI-PEG20 (pegylated arginine deiminase), we achieved enhanced apoptosis and accelerated cell death in melanoma cell lines. This implies a switch from autophagy to apoptosis. In our current investigation, we found that TRAIL could induce the cleavage of two key autophagic proteins, Beclin-1 and Atg5, in the combination treatment. Using specific inhibitors for individual caspases, we found that caspase-8 inhibitor could completely abolish the cleavage. Furthermore, caspase-8 inhibitor was able to fully reverse the enhanced cytotoxicity induced by TRAIL. Inhibitors for caspase-3, 6, 9, and 10 were able to block the cleavage of these two autophagic proteins to some extent and correspondingly rescue cells from the cytotoxicity of the combination of TRAIL and arginine deprivation. In contrast, calpain inhibitor could not prevent the cleavage of either Beclin-1 or Atg5, and was unable to prevent cell death. Overall, our data indicate that the cleavage of Beclin-1 and Atg5 by TRAIL-initiated caspase activation is one of the mechanisms that lead to the enhancement of the cytotoxicity in the combination treatment.\nKeywords ADI-PEG20 Atg5 Autophagy Beclin-1 Caspase TRAIL ASJC Scopus subject areas Clinical Biochemistry Molecular Biology Cell Biology", "pred_label": "__label__POS", "pred_score_pos": 0.7603670954704285}
{"content": "Teeth that are severely compromised or decayed can be saved via endodontic therapy, or what is commonly known as root canals. Root canal therapy removes diseased or infected dental pulp from the inside part of a tooth. Endodontic treatment aims to restore a tooth’s function and save a damaged or decayed tooth from extraction.\nIf you’re interested in root canal treatment in Newton, MA, please contact Newton Wellesley Dental Partners. Our dentist in Newton, MA, is highly skilled and well-versed in painless root canal procedures.\nCertain signs are indicative of the need for a root canal procedure. These include:\nWe advise our valued patients to book regular dental exams and cleanings with our dentist to prevent common dental problems. The sooner you catch a dental issue, the more conservative the prescribed treatment. Severe tooth damage often develops over a lengthy period, and you can take steps to prevent dental challenges from escalating.\nThere are two types of root canals—non-surgical and surgical root canals. Non-surgical root canals are the most common type. During a non-surgical root canal, the dentist performs a procedure that is similar to a deep filling. To achieve this, the dentist accesses your root canals using dental files. The dentist removes all diseased pulp and then disinfects the root canals using sodium hypochlorite. This solution eliminates all microbes from the root canals. Finally, the dentist seals the canals using gutta-percha material. In instances where the tooth structure is severely compromised, the dentist may recommend dental crowns to restore the tooth’s function and appearance.\nA surgical root canal in Newton, MA, is reserved for cases where non-surgical endodontic therapy is insufficient. Surgical root canals may be recommended as first-line treatments or as part of endodontic retreatment, depending on the individual’s circumstances. Endodontic retreatment refers to the additional procedures a patient undergoes after an initial root canal treatment and fails to get relief.\nApicoectomy, or root-end resection, is a type of surgical root canal treatment. An apicoectomy involves the removal of the root ends of a tooth. There are other endodontic surgery types, and our dentist will discuss them with you if necessary.\nAre you looking for a trusted dental practice that offers root canals near you? Reach out to Newton Wellesley Dental Partners today to schedule a visit with our dentist in Newton, MA.", "pred_label": "__label__POS", "pred_score_pos": 0.8129504323005676}
{"content": "A rapid method has been developed to determine enterococci using immunomagnetic separation and bioluminescence. Small paramagnetic beads are coated with antibodies having a specific affinity to enterococci. The captured enterococci are quantified by bioluminescence. The entire procedure takes 30 minutes without a pre-enrichment step. After developing the method, field tests were performed in California. Eight beach samples were provided for determining enterococci using the rapid method. At the same time, the same samples were tested with traditional methods performed by 26 local laboratories. The results show a significant agreement between the two methods. In six out of the eight locations, the predictions based upon the rapid method agreed well with the average values by the traditional methods in determining the quality of swimmable water. Among these, the four predictions were very close to the average colony count. The results also showed the sensitivity of the rapid method (<104 CFUs/100 ml).", "pred_label": "__label__POS", "pred_score_pos": 0.5608540773391724}
{"content": "Yes, you heard it right. This common household material can revolutionize data storage and computing. Want to know about it further? Follow the details that we have mentioned in the paragraphs below.\nA very non-toxic and easy-to-obtain material found in the household paint might be beneficial for one of the most significant machine learning issues.\nThe latest scientific journal that got published recently by one of the teams working at Sandia National Laboratories, in collaboration with researchers from the University of Michigan, stated that the material – titanium oxide, which we can often be seen in varnishes and paints, can effectively improve the energy efficiency which would, in turn, increase the performance of computer chips.\nIf the computer chip will get coated with titanium oxide and then gets heated to more than 150 degrees Celsius, there are significant chances that some of the oxygen molecules will get removed, which will result in the creation of oxygen vacancies. This entire process will make the material a lot more electrically conductive, which will let it store a more significant amount of information.\nThis discovery is crucial, as it will undoubtedly change the way computers store and process data. This, in turn, will result in saving a significant amount of energy.\nAll the information gets stored in one place before computers transfer it to another location for processing in the current scenario. This constant transfer process develops a significant amount of strain on the systems in processing power and energy usage. If this unnecessary power loss can be minimized, the oxygen vacancies will handle a more significant memory that requires intensive energy.\nThe lead author of the journal, Yiyang Li, described that they have tried to organize the storage and processing at the same place. However, that might now be new; they succeeded in doing it in a repeatable and predictable manner. In a general aspect, too, it takes a significant amount of energy to do machine learning. This is because you move it back and forth. One of the significant barriers while machine learning is power consumption.\nFinal Verdict\nThis latest discovery related to titanium oxide might effectively help in image processing, voice recognition, and autonomous vehicles. However, these are only early-day predictions. A lot of research is yet to be done on this subject to scale it up before there’s an employment of the oxygen vacancies in the consumer or business technology.", "pred_label": "__label__POS", "pred_score_pos": 0.9656134247779846}
{"content": "We have a full time, Fume Hood Certification Specialists available to evaluate and certify your fume hoods. It is recommended that all fume hoods have a minimum annual certification performed to insure proper function.\nA service call by our Fume Hood Specialist includes the following: Identify the fume hood airflow requirements and ensures they operate in conjunction with the building HVAC system. When purchasing a new fume hood, will help ensure you have the right hood for your application. Verifies proper installation of your fume hood. Ensures proper fume containment, airflow and exhaust discharge. Provides you with \"ASHRAE 110-1995-All Test\" results and certifies hoods in compliance with established test criteria. Chemical Fume Hood Test Methodologies. ASHRAE 110 - 1995:Method for Testing Performance of Laboratory Fume Hoods - this approach is the one quantitative measure of hood performance. This test is mandated by ANSI Z9.5 for all new hood installations. Recommendation: Mandated for every new hood. Recommended for every hood to gain a complete understanding of the hoods performance. LTMW 1105 SOP:This approach is comprehensive and provides a qualitative review of all factors that may impact hood performance. All procedures outlined in OSHA 1910.1450 as it relates to chemical fume hood testing, ANSI Z9.5 and ASHRAE 110 - 1995 (excepting tracer gas testing) are followed. A comprehensive report detailing hood performance vs. target performance, concerns and recommendations, original field checklists and equipment calibration certificates are provided. Recommendation: We recommend this method for annual chemical fume hood certification and preventative maintenance. FVS - Face Velocity and Smoke Testing:This is a simple test following the methods of the ASHRAE 110 - 1995 Method and ANSI Z9.5 - 1992 Version. Face Velocity is recorded with real time data logging - the original data tape is included with the report. Large volume smoke challenge and low volume smoke tests are conducted and the results recorded in the report. Recommendation: Semi-annual or quarterly checks between LTWM 1105 SOP annual certification.", "pred_label": "__label__POS", "pred_score_pos": 0.9326705932617188}
{"content": "I employ an Evidence-Based Creative Teaching EBCT approach, which is fully documented in my recent book, Creative Teachers: Self-directed Learners (Springer, 2020).\nEBCT has its roots in a synthesis of current research from the behavioural, cognitive and neurosciences, the pioneering research on the effectiveness of different instructional methods and strategies by John Hattie (2008, 2012), and the application of this work by Geoff Petty (2006; 2018), who established Evidence-Based Teaching in the global educational literature.\nI evolved and developed EBCT from over a decade of extensive research and application in designing and facilitating instruction, validated its effectiveness across most educational and vocational sectors, in several countries, and with over 15,000 teaching/training professionals in a range of cultural contexts.\nTo meet the needs of teaching/training professionals in this rapidly changing educational landscape, I am providing a fully online EBCT approach to key areas of professional development in teaching/training. This approach includes, pre-recorded and live webinars, self-contained interactive online workshops, and synchronous tutorials using Zoom. The learning mediums are customised to context and can be further enhanced through personalized coaching when required/needed.", "pred_label": "__label__POS", "pred_score_pos": 0.9317271113395691}
{"content": "In Indiana, the age of sexual consent is 16. However, this number is nearly arbitrary, as the law permits individuals aged 14 and 15 to consent to sex with anyone younger than 18. Thus, despite the age of majority, a 15-year-old and 17-year-old could legally have sex in Indiana, but if the older person were 18, it would be a crime.\nSort of. Indiana takes a few notable deviations from standard age of consent laws.\nMarriage: Under Indiana law, it is a defense if the minor is married. The minimum age for marriage in Indiana is 15, and therefore there is an exception carved out to facilitate that.\nClose-in-age: Technically, this \"close-in-age\" provision is a defense instead of an exception, but it allows a 4 year gap in age if the two are in an ongoing personal relationship. Thus, ostensibly, a an 18-year-old could avoid prosecution for having sex with a 14-year-old, provided the two were in an ongoing romantic relationship as defined by Indiana law.\nMistake of fact: Indiana is one of the few states that provides for a mistake of fact in their statutory rape laws. Thus, if someone has a reasonable, good-faith belief the individual they are having sex with is 16 or older, they can avoid criminal liability.\nIf you believe you have violated Indiana’s age of consent laws, you should contact an attorney immediately. A criminal defense lawyer can help you understand the law, what your options are, and represent you if the state decides to press charges.", "pred_label": "__label__POS", "pred_score_pos": 0.851881206035614}
{"content": "In 2018 the Turkish Personal Data Protection Board\n(\"\nBoard\") launched the online\nregistration platform called VERBIS for Data\nControllers 1.\nAccordingly, the Data Controllers are now required to register\nto with VERBIS system\nbefore 30 September 2019.\nUnless there is an exemption, registration is made via a personal\ndata inventory prepared as per the guidelines of the Board.\nThe data inventory (\"\nData Inventory\")\nshould include the type and category of the personal data collected\nand retained, the purpose, duration, method of the processing\nactivity and other information deemed necessary by the Board.\nPreparation of the Data Inventory could be a time consuming process and may require a couple of months to complete therefore both local and foreign corporations should already be taking action to ensure compliance.\nThe Board held the following categories of Data Controllers exempt from registration to VERBIS:\n- Data Controllers who have less than 50 employees\nand annual balance sheet below TRY 25 million,\nprovided that such Data Controller's main activity is not the\nprocessing of special category personal data;\n- Data Controllers who only process data manually, and which processing is not part of any data registration system;\n- Public notaries;\n- Associations (\"\nDernekler\"), Foundations\n(\" Vakıflar\") and Unions\n(\" Sendikalar\").\n- Political parties;\n- Registered Lawyers;\n- Certified public accountants and independent accountant and financial advisors;\n- Customs brokers;\n- Mediators;\nEven the foregoing entities exempt from registration in VERBIS are still required to comply with the requirements of the Code. We anticipate that even those currently exempted may be required to register in the future therefore a robust compliant data processing policy is recommended.\nIt should be noted that foreign entities even without an\nestablishment in Turkey or permanent residence, which process data\nof local residents in Turkey\nare not exempt from\nregistration and so they will be required to register\nbefore they start processing data. Processing without being\nregistered could give rise to a potential fine. Sanctions for Failure to Register within the Deadline\nUnder the Data Protection Law\n(\"\nLaw\"), Data Controllers who fail to\nfulfill the obligation of registration by the deadline of 30\nSeptember 2019 are subject to penalties between TRY 20,000 and TRY\n1,000,000.\nIn this context it is strongly recommended that all corporate entities in Turkey both foreign and local, take the necessary action to prepare for registration before the Deadline if they collect personal data from Turkey.\nIf you have any questions of require any further assistance with the foregoing we will be happy to help.\nFootnote\n1 \"\nData Controllers\" being\nreal persons and legal entities that collect and retain personal\ndata from Turkish residents. The content of this article is intended to provide a general\nguide to the subject matter. Specialist advice should be sought\nabout your specific circumstances.", "pred_label": "__label__POS", "pred_score_pos": 0.7559446096420288}
{"content": "Distinct metabolic pathways mediate regulatory T cell differentiation and function. Hashimoto H., McCallion O., Kempkes RWM., Hester J., Issa F.\nInvestigation of the cellular metabolic pathways of immune cells, or immunometabolism, is a field of increasing interest. An understanding of immunometabolism provides routes to modifying T cell function for therapeutic purposes. Here, we review immunometabolism with a specific focus on regulatory T cells (Tregs). While T cells are known to switch their metabolic profile from oxidative phosphorylation to aerobic glycolysis upon activation, in vitro-induced Tregs display alternate metabolic characteristics which may be related to their specialised suppressive function. Recent data suggest that the preferential pathways employed by Tregs differ in vivo and ex vivo. Metabolic 'harshness', particularly the deterioration of glycolysis, positively affects Treg differentiation and function, while negatively correlating with Treg clonal expansion and migratory capacity. These context-dependent findings provide new insights into the behaviour of Tregs with implications for both tumour immunology and autoimmunity. This review examines the field in detail, offering an overview of our current understanding of Treg immunometabolism.", "pred_label": "__label__POS", "pred_score_pos": 0.9853808879852295}
{"content": "【标题】儿童和Minecraft：一项关于儿童数字游戏的调查\n【摘要】诸如Minecraft的数字游戏已经占据了很多儿童媒介食谱中的显著位置。然而，人们对于关于谁在玩、和谁玩、如何玩的了解却不明晰。本文对753名3～12岁儿童家长进行了有关儿童参与Minecraft的定量调查。我们的结果证实，Minecraft是占据该年龄段主导地位的数字游戏，尤其是在平板设备上。我们提供了一个明显的、关于儿童玩Minecraft和参与元游戏材料的早期性别化的证据。这项研究特别推动了旨在确保儿童在数字游戏相关文化空间中性别平等的努力。它还强调了收集游戏特有的描述性信息的重要性，而不是将研究局限于对“屏幕时间”的总体测量。\nAbstract\nDigital games such as Minecraft currently hold a position of significance in the media diets of many children. However, little is known explicitly about just who plays, with whom and how. This article presents the quantitative results of a survey of 753 parents of children aged 3–12 years about their child’s engagement with Minecraft. Our results establish Minecraft as the dominant digital game title played by this age group, particularly on tablet devices. We provide evidence of a marked early gendering of children’s Minecraft play and engagement with meta-game material. This research gives particular impetus to efforts aimed at ensuring gender equity in digital game–related cultural spaces inhabited by children. It also highlights the importance of collecting game-specific descriptive information, rather than limiting studies to aggregate measures of ‘screen time’.\n【引用信息】\nChildren and Minecraft: A survey of children’s digital play\nJane Mavoa, Marcus Carter, and Martin Gibbs\nNew Media & Society\nVol 20, Issue 9, pp. 3283 – 3303 First Published December 19, 2017\nhttps://doi.org/10.1177/1461444817745320", "pred_label": "__label__POS", "pred_score_pos": 0.8015514612197876}
{"content": "The Fasting Blood Glucose test, which is also called Fasting Blood Sugar (FBS) test, is a blood test that measures blood sugar levels. If you have elevated levels, it shows that your body cannot properly handle sugar, which can be a sign of diabetes and insulin resistance. For this test, you will be required to fast (not eat or drink) for 8 to 12 hours beforehand, following the guidance you got from your healthcare provider. A blood sample will be taken and sent to the lab, where the glucose levels are analyzed. A fasting glucose level of less than 100mg/dL is considered normal, a measurement between 110 – 125 mg/dL is a sign for impaired fasting glucose (for example because of pre-diabetes), and a value greater than 126 mg/dL in two or more sample is considered a sign of diabetes. Follow the instructions of your healthcare provider before, during and after the test.\nSources: Mayo Clinic. Diabetes. https://www.mayoclinic.org/diseases-conditions/diabetes/diagnosis-treatment/drc-20371451 (accessed 3. August 2020) Cleveland Clinic. Blood Sugar Tests. https://my.clevelandclinic.org/health/diagnostics/16790-blood-sugar-tests (accessed 3. August 2020) WebMD. Diabetes Testing. https://www.webmd.com/diabetes/diagnosing-type-2-diabetes (accessed 3. August 2020)", "pred_label": "__label__POS", "pred_score_pos": 0.9316849112510681}
{"content": "Internal auditors are tasked with bringing objectivity to the assurance functions they perform within an enterprise. They are also increasingly called upon to provide a wide range of advisory services, stretching from managing risk to enhancing company performance. In a recent conversation with\nThe CPA Journal, Mark Martinelli, chief audit executive for Synchrony, discussed the issues currently facing internal auditors. He describes how the internal audit function has changed over time and how the bar has been raised. Martinelli also characterizes internal auditing as a unique opportunity for CPAs and a field that features strong competition for talented individuals.", "pred_label": "__label__POS", "pred_score_pos": 0.9897636771202087}
{"content": "Pfizer announced new, longer-term data from the Intergroup Exemestane Study (IES) showing that women who switched to Aromasin (exemestane tablets) after taking tamoxifen for 2-3 years experienced a significant reduction in the risk of disease-free survival (DFS) events compared to women who continued on tamoxifen for a full five years of treatment. This study was a randomized, double-blind, multinational trial of postmenopausal women with early breast cancer evaluating the clinical benefits of switching 2,352 patients to Aromasin after 2-3 years of tamoxifen versus continuing 2,372 patients on tamoxifen for a full 5 years of therapy. The primary endpoint of the study was DFS in the intent-to-treat (ITT) population. In postmenopausal women with early breast cancer at a median follow-up of 91 months, switching to AROMASIN after two to three years of tamoxifen, for a total of five years of treatment, was shown to result in a 16% reduction in the risk of DFS events, defined as local or distant recurrence of breast cancer, contralateral breast cancer, or death from any cause, compared to staying on tamoxifen for five years (HR=0.84; 95% CI: 0.75-0.94; P=0.002) in the ITT population. For the secondary endpoint of overall survival in the ITT population, there was an 11% relative risk reduction of death. There was a statistically significant 14% reduction in the risk of death noted in the ER+/unknown population (HR=0.86: 95% CI: 0.75-0.99 P=0.04).\nAromasin is indicated for the adjuvant treatment of postmenopausal women with estrogen-receptor positive early breast cancer who have received 2-3 years of tamoxifen and are switched to Aromasin for completion of a total of five consecutive years of adjuvant hormonal therapy. Aromasin is also indicated for the treatment of advanced breast cancer in postmenopausal women whose disease has progressed following tamoxifen therapy.\nFor more information call (800) 438-1985 or visit www.pfizer.com.", "pred_label": "__label__POS", "pred_score_pos": 0.5181171298027039}
{"content": "Beyond Reading, Writing, and Arithmetic: The Role of Teachers and Schools in Reporting Child Maltreatment\nNearly 4 in 10 children report experiencing maltreatment by adulthood. Early detection mitigates maltreatment’s negative effects. Yet factors that drive early detection remain understudied. We examine one possible source of early detection: educators in school settings. Administrative data on reports of child maltreatment across the U.S. over a 14-year period allows us to use two different regression discontinuity methods, one based on school-entry laws and one on school calendars. Both methods show education professionals are reporting cases that would have been missed otherwise. These findings suggest that improved training and support of educators may improve society's ability to help children and families.\nAny opinions and conclusions expressed herein are those of the authors and do not necessarily represent the views of the U.S. Census Bureau or the National Bureau of Economic Research. We appreciate the helpful comments from seminar participants at the NBER Summer Institute Children’s Program Meeting, New York University’s Wagner Graduate School of Public Service and Steinhardt School, Columbia University, the University of Virginia’s Batten School of Public Policy and Curry School of Education. We thank Carina Chien and Martha Johnson for excellent research assistance. Data used in this article are a version of the National Child Abuse and Neglect Data System (NCANDS, HHS ACF Children’s Bureau 2015) Child File, which was shared with us as part of a unique pilot secure micro-data program. All errors and omissions are our own.", "pred_label": "__label__POS", "pred_score_pos": 0.7508619427680969}
{"content": "Millions of U.S. adults have high blood pressure, yet most do not have it under control. Research cited by the American Heart Association notes that remote cardiac monitoring can greatly reduce patient blood pressure compared to typical care and self-monitoring alone. The PY-802-LTE Blood Pressure Monitor makes remote blood pressure monitoring easy for patients, care providers and developers. Features include:", "pred_label": "__label__POS", "pred_score_pos": 0.6467502117156982}
{"content": "(Washington, D.C., March 19, 2020) – U.S. Secretary of Agriculture Sonny Perdue today announced a partnership between the U.S. Department of Agriculture (USDA) and the U.S. Department of Labor (DOL) to help facilitate the identification of foreign and domestic workers that may be available and eligible to transfer to other U.S. agricultural sector employers to fulfill critical workforce needs within the U.S. under existing regulatory authority during the COVID-19 pandemic.\n“Ensuring minimal disruption for our agricultural workforce during these uncertain times is a top priority for this administration,” Secretary Perdue said. “President Trump knows that these workers are critical to maintaining our food supply and our farmers and ranchers are counting on their ability to work. We will continue to work to make sure our supply chain is impacted as minimally as possible.”\n“American farmers and ranchers are at the frontlines of maintaining the nation’s food supply,” Secretary Scalia said. “In these unprecedented times, it is critical for them to have the workforce they need. This new partnership between USDA and DOL will help support our farmers, ranchers, and American families.”\nBackground:\nUSDA and DOL have identified nearly 20,000 H-2A and H-2Bcertified positions that have expiring contracts in the coming weeks. Therewill be workers leaving these positions who\ncould be available totransfer to a different employer’s labor certification. The data,available on www.farmers.gov/manage/h2a,includes the number of certified worker positions, the current employer nameand contact, attorney/agent name and contact, and the worksiteaddress. This information will be a resource to H-2A employers whoseworkforce has been delayed because of travel restrictions or visa processinglimitations. Employers should be aware that all statutory and regulatoryrequirements continue to apply. Employers are encouraged to monitor www.travel.state.govfor the latest information and should monitor the relevant Embassy/Consularwebsites for specific operational information.", "pred_label": "__label__POS", "pred_score_pos": 0.7765475511550903}
{"content": "Isolated spinning neutron stars, asymmetric with respect to their rotation axis, are expected to be sources of continuous gravitational waves. The most sensitive searches for these sources are based on accurate matched filtering techniques that assume the continuous wave to be phase locked with the pulsar beamed emission. While matched filtering maximizes the search sensitivity, a significant signal-to-noise ratio loss will happen in the case of a mismatch between the assumed and the true signal phase evolution. Narrow-band algorithms allow for a small mismatch in the frequency and spin-down values of the pulsar while coherently integrating the entire dataset. In this paper, we describe a narrow-band search using LIGO O2 data for the continuous wave emission of 33 pulsars. No evidence of a continuous wave signal is found, and upper limits on the gravitational wave amplitude over the analyzed frequency and spin-down ranges are computed for each of the targets. In this search, we surpass the spin-down limit, namely, the maximum rotational energy loss due to gravitational waves emission for some of the pulsars already present in the LIGO O1 narrow-band search, such as J1400−6325, J1813−1246, J1833−1034, J1952+3252, and for new targets such as J0940−5428 and J1747−2809. For J1400−6325, J1833−1034, and J1747−2809, this is the first time the spin-down limit is surpassed.", "pred_label": "__label__POS", "pred_score_pos": 0.5608431100845337}
{"content": "Chicago, IL 60601\nFREE CONSULTATIONS 312-945-1300 Birth Injuries From Prolonged Labor Addressing Complications from Stalled or Arrested Labor - Illinois Medical Negligence Attorney\nLabor and delivery is a commonplace procedure that happens every day, but complications may occur during birth that present risks to the health of the child or the mother. Prolonged labor is one issue that could result in birth injuries, and in these cases, medical personnel need to act to ensure that a child is delivered safely.\nWhat Is Prolonged Labor?\nWhen a mother enters the active stage of labor, doctors or nurses will monitor a variety of factors to ensure that labor is progressing at the expected rate. These factors include the dilation and thinning of the cervix, the position of the child in the mother's pelvis, and the length and frequency of contractions. Labor may be considered prolonged if it lasts longer than 20 hours (or just 14 hours for second or third pregnancies) or if the cervix does not dilate at the expected rate for four hours.\nCauses of Prolonged Labor\nLabor may become slowed or arrested for a variety of reasons, including:\nCephalopelvic disproportion - The child's head may be too large to move through the birth canal. Malpresentation - Children are typically delivered head-first. If the child is in the breech position or is not facing toward the mother's back, this may lead to slowed or arrested labor. Weak contractions - If contractions are not strong enough, they may not cause the cervix to dilate at the proper rate. Pain medications administered to the mother may result in slowed or weakened contractions. Risks of Prolonged Labor\nWhen labor lasts too long, this can lead to health issues that affect both the child and the mother, including:\nAsphyxia - Prolonged labor can result in issues that affect the placenta or umbilical cord, such as placental abruption, and this may result in an interruption of the flow of blood and oxygen to the child. A child may also experience asphyxia if he or she becomes lodged in the birth canal. Oxygen deprivation can lead to brain injuries, including fetal stroke, hypoxic ischemic encephalopathy (HIE), or periventricular leukomalacia (PVL). Fetal distress - A lengthy labor may cause a child to experience a low or irregular heart rate or other forms of distress. This may be caused by the intense contractions that can result if drugs such as Pitocin are administered to speed up the labor process, and it can result in complications such as meconium aspiration. Birth trauma - If the child remains in the birth canal for too long, this can put too much pressure on the head and brain, resulting in injuries such as skull fractures. If a child has trouble progressing through the birth canal, a doctor may use forceps or vacuum extractors to aid in the delivery, and improper use of these tools can lead to brain injuries or brachial plexus injuries. Infections - Prolonged labor increases the chances that the child will contract an infection during birth or experience sepsis. Maternal injuries - Lengthy labor increases the risks of maternal infections, vaginal lacerations, and post-partum hemorrhaging. Help With Injuries From Prolonged Labor\nA mother and child should be closely monitored by hospital staff throughout labor and delivery, and if labor is not progressing at the proper rate, medical intervention may be needed. In some cases, Cesarean delivery may be necessary in order to reduce the risk of injury to the child or mother.\nThe effects of injuries that occur due to lengthy labor can be far-reaching, and they may have a long-term impact on the child's development or the mother's health. If you or your child have suffered harm because of prolonged labor, you will want to understand whether medical negligence may have played a part. The Birth Injury Law Alliance can review your case and help you understand the options that are available to you. For a free consultation and case evaluation, contact us at\n312-945-1300.", "pred_label": "__label__POS", "pred_score_pos": 0.8339977860450745}
{"content": "By Josh Loeb\nThe RCVS is in advanced discussions about adopting a lower standard of proof in disciplinary hearings for vets and registered vet nurses (RVNs).\nThe move, which would bring the college into line with other professional regulators, could lead to more charges against vets and RVNs being proven.\nThe college’s council is expected to make a decision about the matter in the near future.\nCurrently, the RCVS uses the criminal standard of proof, whereby allegations must be proven beyond reasonable doubt.\nSince the college is one of the last, if not the last, remaining UK regulators to use this standard, it is open to a legal challenge.\nUse of the criminal standard places a relatively high burden on the college when attempting to prove the truth of allegations made against vets. By contrast, ‘on the balance of probabilities’ – the standard used by other regulators and...", "pred_label": "__label__POS", "pred_score_pos": 0.7396109104156494}
{"content": "Celina’s PhD project will assess the adaptive capacity of kelp forests in a changing climate. Kelp forests are among the most productive ecosystems in the world while providing numerous ecosystem services. Yet, these valuable habitats are declining due to climate change and other anthropogenic influences. As a result, we can see a decrease in kelp performance and eventually an ecosystem collapse leading to a shift from kelp forests to communities dominated by turf algae. However, different kelp populations show varying responses to climatic stress. Identifying these differences will be crucial in predicting possible future scenarios and improving restoration efforts. The aim of this project is therefore to identify thresholds and feedback mechanisms resulting in the loss of kelp forests, and to provide novel solutions to promote kelp forest restoration and resilience.", "pred_label": "__label__POS", "pred_score_pos": 0.9904832243919373}
{"content": "Analysis and Optimization of Installed Antenna Performance Time: Mon 2020-03-09 13.00 Subject area: Electrical Engineering Doctoral student: Henrik Frid , Skolan för elektroteknik och datavetenskap (EECS) Opponent: Professor Hugh Griffiths, University College London Supervisor: B. Lars G. Jonsson, Elektroteknisk teori och konstruktion Abstract\nThis Ph.D. thesis consists of six papers, which are labeled with roman numerals. Papers I-III have already been presented in a licentiate thesis published in2017, and this Ph.D. thesis therefore focuses on Papers IV-VI. All six papersare within the scope of microwave and antenna engineering, with applications to radar, electronic warfare (EW), radio astronomy or communications.\nThe common theme for Papers IV-VI is installed antenna performance (IAP). These papers present three methods for solving three problems related to IAP, by using information available in the installed far-field data. In these papers, we address the main challenges within the scope of IAP, i.e. antenna placement, electromagnetic compatibility (EMC), estimation of installed system performance (particularly direction-of-arrival (DoA) estimation accuracy)and optimization methods to compensate for or minimize installation effects. The presented methods make no simplifying assumptions regarding the antennas or their installation, and instead rely on using the installed far-field data, which is obtained through computational electromagnetics. These methods are therefore valid for generic array antennas. The presented methods are useful for antenna placement studies, i.e. as input for the decision on antenna placement on a platform such as an aircraft, ship, satellite or car.\nPaper IV considers the problem of antenna placement with respect to EMC. A platform, such as an aircraft, ship, satellite, or car, may have a large number of radio-frequency (RF) systems installed onboard. Since some systems transmit a high RF power, while other systems aim to receive weak RF signals, there is a significant risk for unwanted electromagnetic interference (EMI) due to an insufficient isolation between the antennas associated with each RF system. This paper presents a method for estimating the isolation between antennas installed on the same platform, in order to determine therisk for EMI as a function of antenna placement. Finally, a numerical case-study is presented, considering two monopole antennas installed on a small aircraft under line-of-sight conditions. Results are also presented for other installation configurations, where the antennas are not within line-of-sight.\nPaper V considers antenna placement and radome design with respect to DoA estimation accuracy. Firstly, we define the term \"installation error\" applied to DoA estimation. A method for determining the DoA estimation accuracy for a specific installation is thereafter presented. The paper ends with a numerical case-study for an array antenna installed behind a single-shell radome in the tail of a realistic full-scale model of a fighter aircraft.\nPaper VI presents a method to compensate for radome effects on radiation patterns for array antennas. A convex optimization approach is used to minimize the side-lobe level, while taking the radome effects and mutual coupling into account. The paper ends with a numerical case-study for amonopulse-array installed behind a single-shell radome.", "pred_label": "__label__POS", "pred_score_pos": 0.7772995233535767}
{"content": "Islamist groups continue to be significant non-state actors in several Muslim-majority states. However, nations such as Saudi Arabia, Iran, Turkey, Pakistan, and others have weaponized religious discourse – both to manage Islamists at home and pursue foreign policy objectives abroad. Join us as we assess how variant Islams shape the geopolitics of these countries and vice-versa.\nDr. Peter Mandaville is a Professor of Government and Politics in the Schar School of Policy and Government at George Mason University. He also is a Nonresident Senior Fellow in Foreign Policy Studies at the Brookings Institution and Senior Research Fellow at Georgetown University’s Berkley Center for Religion, Peace & World Affairs. Mandaville previously served as a Senior Advisor in the Office of Religion and Global Affairs at the U.S. State Department and as a member of former Secretary of State Hillary Clinton’s Policy Planning Staff.\nDr. Kamran Bokhari is Director of Analytical Development at the Center for Global Policy. He also is a national security and foreign policy specialist at the University of Ottawa’s Professional Development Institute. Bokhari has served as the Central Asia Studies Course Coordinator at the U.S. Department of State’s Foreign Service Institute.", "pred_label": "__label__POS", "pred_score_pos": 0.8414208292961121}
{"content": "Perfect Law and Legal Definition\nPerfect is subject to different meanings, but in the context of real estate, it refers to the act of making complete or taking all required steps to obtain a result, such as obtaining a lien or other security by legal action or completing and filing all documents to present a case to a court of appeals. It is often used to refer to the filing of a lien with the appropriate entity responsible for land records, such as the county recorder's office. A mechanic's lien for labor and/or materials used to improve real property is \"perfected\" by filing a lawsuit and obtaining a judgment that the lien attaches to the property.\nIf a creditor has liens against him/her by more than one person, the person who has perfected their lien will get priority over a lien that is not perfected. State law varies, but the lien created by the statutory framework must be perfected and preserved within the time period set forth in the statutes.", "pred_label": "__label__POS", "pred_score_pos": 0.6349203586578369}
{"content": "Abstract\nA significant number of people living with human immunodeficiency virus type 1 (HIV-1) suffer from HIV-associated neurocognitive disorders (HAND). Many previous studies investigating HIV in astrocytes as a heterogenous population have established the relevance of astrocytes to HIV-associated neuropathogenesis. However, these studies were unable to differentiate the state of infection, i.e., active or latent, or to evaluate how this affects astrocyte biology. In this study, the pseudotyped doubly labeled fluorescent reporter red/green (R/G)-HIV-1 was used to identify and enrich restricted and active populations of HIV\n+ astrocytes based on the viral promoter activity. Here, we report that the majority of human astrocytes restricted R/G-HIV-1 gene expression early during infection and were resistant to reactivation by vorinostat and interleukin 1β. However, actively infected astrocytes were inducible, leading to increased expression of viral proteins upon reactivation. R/GHIV- 1 infection also significantly decreased the cell proliferation and glutamate clearance ability of astrocytes, which may contribute to excitotoxicity. Moreover, transcriptome analyses to compare gene expression patterns of astrocyte harboring active versus restricted long terminal repeats (LTRs) revealed that the gene expression patterns were similar and that the active population demonstrated more widespread and robust changes. Our data suggest that harboring the HIV genome profoundly alters astrocyte biology and that strategies that keep the virus latent (e.g., block and lock) or those that reactivate the latent virus (e.g., shock and kill) would be detrimental to astrocyte function and possibly augment their contributions to HAND. IMPORTANCE More than 36 million people are living with HIV-1 worldwide, and despite antiretroviral therapy, 30 to 50% of the people living with HIV-1 suffer from mild to moderate neurocognitive disorders. HIV-1 reservoirs in the central nervous system (CNS) are challenging to address due to low penetration of antiretroviral drugs, lack of resident T cells, and permanent integration of provirus into neural cells such as microglia and astrocytes. Several studies have shown astrocyte dysfunction during HIV-1 infection. However, little is known about how HIV-1 latency affects their function. The significance of our research is in identifying that the majority of HIV + astrocytes restrict HIV expression and were resistant to reactivation. Further, simply harboring the HIV genome profoundly altered astrocyte biology, resulting in a proinflammatory phenotype and functional changes. In this context, therapeutic strategies to reactivate or silence astrocyte HIV reservoirs, without excising proviral DNA, will likely lead to detrimental neuropathological outcomes during HIV CNS infection. Keywords Astroglia HIV-1 latency HIV-associated neurocognitive disorders (HAND) Neuroinflammation RNA sequencing Transcriptomics Viral reservoirs", "pred_label": "__label__POS", "pred_score_pos": 0.7136086225509644}
{"content": "What is a Sunroom?\nA sunroom is a covered area connected to a house that usually has screened openings to allow airflow. They often act as sitting rooms — a peaceful place to enjoy conversation with friends and family or to relish by yourself in a good book. Sometimes, they are constructed using materials that can withstand cold temperatures. They often go by other names, such as solariums or patio rooms.\nKinds of Sunrooms\nThere are two primary kinds of sunrooms, three and four seasons. Three-seasons sunrooms are constructed using light-weight materials and usually have screens to allow airflow. They are designed to be enjoyed from spring through fall, but not winter. Four-seasons sunrooms — built with heavier materials, heated, and insulated to shield from the cold — are designed to be used year-round.\nPros of Adding a Sunroom\nAdding a sunroom to your home has several meaningful benefits that are worth considering. They add space to your home that is connected to the outdoors — a place to enjoy some fresh air without having to leave the house. They act as an additional room to gather with friends and family, and since three out of the four walls of your sunroom will have exposure to natural light, you won’t need additional lighting during the day. They may also increase the property value of your home, as many view a sunroom as a welcome addition to their home.\nCons of Adding a Sunroom\nWithout a doubt, the largest downside to installing a sunroom is cost. Homeowners will incur expenses for installation, a potential increase in taxes, and increased heating expenses for four-seasons sunrooms. It is also worth noting that, when sitting in your sunroom, you can be seen by people outside of your home. Those valuing privacy can install screens to avoid this.\nCost of Adding a Sunroom\nThe costs associated with adding a sunroom to your home are varied. There are at least five variables that go into a sunroom’s total cost. The primary contributor to the cost of a sunroom is its size. The larger the room, the more expensive it will be. Likely the next largest factor is who you hire to install your new sunroom — a high-end contractor or home remodelers may do a more professional job, but you’ll have to pay substantially more. Likewise, an inexperienced contractor may offer a good deal, but you won’t know how well the job will be completed. These factors must be weighed heavily before making your decision.\nYou want to find a contractor who has experience and references — someone you can trust to do an acceptable job for a fair price. The next largest factor in determining the cost of your new sunroom is your location. For those in places that stay warm year-round, a three-seasons sunroom will do. However, those wishing to install a sunroom in colder climates who wish to enjoy their sunroom year-round, consider a four-seasons sunroom — the additional costs associated with insulating and heating your sunroom will make the project more expensive.", "pred_label": "__label__POS", "pred_score_pos": 0.5065099000930786}
{"content": "This is my summer salad for a few reasons: Its light, bright and super fresh. This salad is named “Detox Salad” because it truly is one. I always recommend that my clients increase the amount of bitter foods they eat into their diet because they have such incredible benefits. For starters, these help to increase digestion as they stimulate the gall bladder and liver to produce digestive juices. Bitter foods also decrease our bodies desire for sugar; so it helps to keep those sugar cravings low.\nSome examples of bitter foods include: Radish, kale, arugula, radicchio, parsnip, beet + beet tops.\nWhether you feel like you need a little reset, are going to a dinner party or want to try something new; this salad should hopefully do the trick.\nIngredients:\n- 2 red or yellow beets, peeled and shaved\n- 2 carrots, peeled and shaved\n- 1 cup kale, chopped\n- 5 radish, chopped\n- ¼ cup radicchio, shaved\n- ½ to 1 cup of parsley\n- 1 tbsp lemon\n- 1 tbsp lime\n- 1 tbsp apple cider vinegar\nMethod:\n1. Simply add all ingredients into a large bowl and mix well.\n2. Transfer to the fridge and allow it to chill for at least one hour.\n3. At this point, you can add more citrus or vinegar\n4. Store in the fridge for up to 4 days\nThat’s it! Its super simple and tastes even better the next day. I hope you enjoy this recipe!\n- Jass\n1 view", "pred_label": "__label__POS", "pred_score_pos": 0.6544134616851807}
{"content": "OR WAIT 15 SECS\nFDA’s final CMC guidance sets expectations for manufacturing and quality for human gene therapy INDs. This article reviews existing analytical applications, focusing on viral vector characterization of impurities.\nIn January 2020, the FDA issued\nFinal Guidance for Industry: Chemistry Manufacturing and Control (CMC) Information for Human Gene Therapy Investigational New Drug Applications (INDs) and other guidance documents for human gene therapies, which set expectations for manufacturing and demonstration of quality (1). These products are applied to deliver genetic material (transgenes) or modified cells that have been designed to alleviate or even eliminate a broad range of diseases that are rooted in the genetics of individuals or populations of patients. Pharmaceutical Technology eBook: Regulatory Sourcebook October 2020 Pages: 52-58\nWhen referring to this article, please cite it as P. Wunderli et al., “Viral Vector API Characterization of Product-Related Impurities,\"\nPharmaceutical Technology Regulatory Sourcebook eBook (October 2020).", "pred_label": "__label__POS", "pred_score_pos": 0.5395913124084473}
{"content": "Your gutters play a vital role in protecting your property from water damage. That's why it's important to ensure they're in top condition at all times. Here, commercial roofing and gutter repair experts from Quality One Roofing Inc discuss the gutter maintenance...Read More\nArchives for February 2020\nCommercial roofing systems can be more challenging to maintain than residential roofs due to their massive size and lack of slope. One thing that can be particularly challenging is accurately identifying signs of damage. In this post, roof repair experts from Quality...Read More", "pred_label": "__label__POS", "pred_score_pos": 0.9930406808853149}
{"content": "Chemistry of the silica magnetic beads\nThe center of the silica magnetic microbead is typically magnetite Fe3O4 or maghemite γ-Fe2O3, giving the bead superparamagnetic properties. In the presence of a magnetic field the beads will become magnetized in the direction of the magnetic field. When the magnet is removed, the beads lose their magnetization completely, reverting back to a fully demagnetized state (standard magnetic materials, as standard iron, have always some remnant magnetization). The beads can be coated in silica, silicon dioxide. This is typically done using a version of the Stöber method, using tetraethyl orthosilicate (TEOS) to create a SiO2 layer around the magnetic bead.\nUses of the silica magnetic bead\nThe silica magnetic bead can be used to isolate or purify nucleic acids from a solution. The beads are now a common and prefered technique for separating genomic DNA, plasmid DNA, or RNA. Silica magnetic beads are used to avoid contaminations and loss of material throughout the purification process, which involves various buffers, salts, and alcohol. The silica magnetic bead binds nucleic acid, but not irreversibly, and can be retained by a permanent magnet device to perform each wash or liquid removal step by simply removing unwanted material from a container while the beads with bound nucleic acid are held by magnetic force to the edge of the container.\nHow to bind nucleic acid to silica magnetic beads\nThe backbone of DNA is negative due to its phosphate backbone. DNA is propelled to bind more efficiently to silica magnetic beads by the presence of a chaotrope. A standard chaotrope called guanidinium hydrochloride is used for this process. A chaotrope will disrupt the bonds of the DNA, particularly to water in a solution. This will allow the DNA to bind elsewhere, such as to the silica coating on the magnetic bead. RNA is purified similarly, but degradation by RNAses is always a concern. For RNA, buffers and solutions are optimized to reduce degradation activity. The main procedure is to put your solution with beads in the presence of a magnet, and remove the contents while keeping the beads. Then the beads can be resuspended in a new desired solution.\nSilica magnetic bead for the laboratory\nThere are multiple methods for nucleic acid separation that have been used before the innovation of the silica magnetic bead. One can do a spin column purification, which involves silica coated columns which capture nucleic acids in the presence of a chaotropic buffer. RNA or DNA can be extracted doing a phenol-chloroform extraction, with extra precautions taken for RNA to avoid degradation. Switching to magnetic beads purifications involved purchasing the magnets specific to biological separation, and the magnetic beads. Some laboratories will make their own beads and pre-coat their own beads. Silica magnetic beads simplify the purification process by having consistent and easy steps. When a solution is in the presence of a magnetic force, the beads will stay in the container while the rest can be completely removed. This reduces the amount of unwanted residual buffer while keeping the yield of the protocol high.", "pred_label": "__label__POS", "pred_score_pos": 0.7023199796676636}
{"content": "TORRANCE — General Motors and Honda on Sept. 3 announced they have signed a non-binding memorandum of understanding following extensive preliminary discussions toward establishing a North American automotive alliance.\nThe scope of the proposed alliance includes a range of vehicles to be sold under each company’s distinct brands, as well as cooperation in purchasing, research and development, and connected services.\nUnder the proposed alliance, Honda and GM would collaborate on a variety of segments in North America, intending to share common vehicle platforms, including both electrified and internal combustion propulsion systems that align with the vehicle platforms. Co-development planning discussions will begin immediately, with engineering work beginning in early 2021.\nThe announcement builds on the agreement signed between the companies in April to jointly develop two all-new electric vehicles for Honda based on GM’s highly flexible global EV platform powered by Ultium batteries. The GM-Honda relationship, which began more than two decades ago, includes recent collaboration between the companies on fuel cells, batteries and the Cruise Origin shared autonomous vehicle.\n“This alliance will help both companies accelerate investment in future mobility innovation by freeing up additional resources. Given our strong track record of collaboration, the companies would realize significant synergies in the development of today’s vehicle portfolio,” said Mark Reuss, president of General Motors.\n“Through this new alliance with GM, we can achieve substantial cost efficiencies in North America that will enable us to invest in future mobility technology, while maintaining our own distinct and competitive product offerings,” said Seiji Kuraishi, executive vice president of Honda Motor Co., Ltd. “Combining the strengths of each company, and by carefully determining what we will do on our own and what we will do in collaboration, we will strive to build a win-win relationship to create new value for our customers. In this way, Honda will continue making steady progress in solidifying our existing business by realizing strong products, strong manufacturing capability and a strong business structure.”\nAn alliance in North America between Honda and GM would leverage the best technologies and generate substantial cost efficiencies from shared vehicle platforms and propulsion systems, joint purchasing, potential manufacturing efficiencies and other collaboration efforts. This would enable both GM and Honda to make greater investments in advanced and next-generation technologies.\nGM and Honda also plan to share R&D and engineering costs for select future co- developed vehicle and propulsion platforms. This would create substantial efficiencies and free up capital, enabling both companies to meet the increasing requirements to invest in various future mobility trends and additional growth opportunities for each company’s distinct brands.\nHonda and GM plan to collaborate in joint purchasing activities to create further cost efficiencies by leveraging both companies’ respective scale, insight and best practices. Purchasing collaboration would be focused on joint sourcing of materials, logistics and localization strategies.\nIntroducing advanced technology is imperative, given shifting consumer and regulatory requirements. To address this challenge efficiently, the alliance would explore combining the R&D efforts between the two companies related to advanced technology areas, including electrical architecture, advanced driver assist systems, infotainment, connectivity and vehicle-to-everything communication.\nIn April, the companies announced that Honda will incorporate GM’s OnStar safety, security and connected services into the two all-new electric vehicles for Honda based on GM’s global EV platform, seamlessly integrating them with HondaLink. Based on that collaboration, GM and Honda will explore further co-development opportunities for future connected services, including GM’s OnStar and infotainment.\nAll facets of the alliance will be governed by a joint committee, comprising senior executives from both companies.", "pred_label": "__label__POS", "pred_score_pos": 0.7580122947692871}
{"content": "This White Paper assesses the multifaceted pervasiveness of corruption in Yemen. It is demonstrated, amongst others, that patronage networks are now emerging among previously marginal or unknown figures and that the financial involvement of Saudi Arabia and the United Arab Emirates has extended patronage across national borders. It is argued that any anti-corruption agenda must aim to understand the complex configuration of patronage networks in Yemen, to be introduced gradually, and to get the buy-in of as wide a group of Yemenis as possible.", "pred_label": "__label__POS", "pred_score_pos": 0.9938403964042664}
{"content": "Mr. Speaker, today I rise to honour all the health care workers who have lost their lives serving this country on the front lines of the COVID pandemic. According to journalist Nora Loreto, of the 6,000 Canadians who have died from COVID-19, over 5,000 are linked to residential care facilities, close to 86%. We know from the unions representing these workers that a significant portion of these workers are racialized.\nI rise to honour Leonard Rodriques, a personal support worker and member of Unifor, whose family says his death was due to a lack of PPE at his workplace. He was buying masks from the dollar store because his workplace was not providing him with PPE. After he was denied the personal protection from his workplace, he was sent home. He tested positive, and when symptoms worsened he went to the hospital. A few hours later, he was discharged from the hospital, and he died two days later. The story of Mr. Rodriques cannot be forgotten. We must begin to collect race-based data related to COVID-19.", "pred_label": "__label__POS", "pred_score_pos": 0.957745373249054}
{"content": "BackgroundAn anesthetic state can reduce adverse airway reaction during laryngeal mask airway (LMA) removal in children. However, the anesthetic state has risks of upper airway obstruction or delayed emergence; so possibly less anesthetic depth is advisable. Caudal analgesia reduces the requirement of anesthetic agents for sedation or anesthesia; it is expected to reduce the sevoflurane requirement for LMA removal. Therefore, we determined the EC50 of sevoflurane for LMA removal with caudal analgesia and compared that to the EC50 without caudal analgesia.MethodsForty-three unpremedicated children aged 1 to 6 yr were enrolled. They were allocated to receive or not to receive caudal block according to their parents' consent. General anesthesia were induced and maintained with sevoflurane and oxygen in air. EC50 of sevoflurane for a smooth LMA removal with and without caudal analgesia were estimated by the Dixon up-and-down method. The LMA was removed when predetermined end-tidal sevoflurane concentration was achieved, and the sevoflurane concentration of a subsequent patient was determined by the success or failure of the previous patient with 0.2% as the step size; success was defined by the absence of an adverse airway reaction during and after LMA removal. EC50 of sevoflurane with caudal block, and that without caudal block, were compared by a rank-sum test.ResultsThe EC50 of sevoflurane to achieve successful LMA removal in children with caudal block was 1.47%; 1.81% without caudal block. The EC50 were significantly different between the two groups (P < 0.001).ConclusionsCaudal analgesia significantly reduced the sevoflurane concentration for a smooth LMA removal in anesthetized children.\nDOI 인용 스타일", "pred_label": "__label__POS", "pred_score_pos": 0.9991768598556519}
{"content": "The ongoing COVID-19 pandemic has brought countless challenges to families across the nation. From adjusting to a work-from-home schedule to attempting to fill the role of our children’s teachers, it has been a time of great transition for all of us as we adapt to our “new normal.”\nTo provide a sense of normalcy and joy during these challenging times, the Kiwanis Club of Orangevale-Fair Oaks provided 24 scooters and helmets to children in the Orangevale area. With the help of a Club Grant from the Cal-Nev-Ha Children’s Fund, the club partnered with the local organization About Kidz to distribute these scooters and helmets to children in their community on June 18, 2020.\nThe project was a massive success for the club! When asked to summarize the project, Club President Sal Arrigo said, “I’ll say it this way – a simple idea from one of our members turned into an extremely rewarding project. The enthusiasm from the kids, About Kidz, and the ‘thank yous’ from the parents was well worth the effort.”\nThe project was even covered by Orangevale Live, a grass-roots marketing collaborative which highlights “home-grown, real-life news” in their community. When asked about the idea by Orangevale Live, Arrigo stated, “Kids want to play, and Kiwanis supports kids.” Well put, Sal! We are honored to partner with clubs to build a better future for our children!", "pred_label": "__label__POS", "pred_score_pos": 0.5264087915420532}
{"content": "“He got up from the meal, took off his outer clothing, and wrapped a towel around his waist. After that, he poured water into a basin and began to wash his disciples’ feet, drying them with the towel that was wrapped around him.” John 13:4–5, NIV.\nThe mood is somber; conversation is dismal, and the spiritual climate is changing. Jesus is aware that His time on earth is concluding and with death quickly approaching He, like anyone who knows they are about to die, imparts a few last life lessons to those who are closest to Him. Instead of relishing in His Kingly glory, Jesus\nchoosesto humble Himself to the role of a servant and washes His disciple’s feet.\nHow can we become confident to serve in a world that promotes self? The spirit of entitlement tries to permeate our lives even though it is contrary to the way Jesus lived His life on earth. Our Lord would have been justified to have a spirit of entitlement, since He was sinless and God dwelling in the flesh, but He chose to be selfless and ministered to His disciples in a way that transcended cultural norms.\nPrayer: Lord, teach me how to invest in people like You do. I pray You would transform how I view ministry and help me serve people, as You do. If a spirit of entitlement rises up in me, help me to realize it right away so I can ask You to purify my heart. l not only desire to love like You love, but I want to serve how You serve. Lead me to someone I can minister to today. In Jesus name.", "pred_label": "__label__POS", "pred_score_pos": 0.9207553863525391}
{"content": "Description\nCommissioned by the Australian Education Union (SA), this report identifies significant shortcomings in the 2003 literacy and numeracy testing conducted in South Australian schools. The authors argue that well-designed standardised tests can be useful as one part of an assessment regime, but the current tests need to be improved considerably.", "pred_label": "__label__POS", "pred_score_pos": 0.6500298976898193}
{"content": "NCASE Resource Library Featured Resources\nThis publication features some of the best resources, including webinars, briefs, and toolkits, available in the online NCASE Resource Library, developed for both practitioners and system builders.\nThese selected resources, curated by NCASE, offer ideas and information for OST system leaders to support recovery from COVID-19.\nThe NCASE Out-of-School Time Professional Development System-Building Toolkit was designed to assist states as they build professional development systems inclusive of school-age providers.\nSearch for Resources ? Search Results Filter By Reset Selections Expand All Filters Topics Resource type Publisher Search Results Filter By\nThis report captures what was shared at an October 2019 Conference about the challenges of teaching social and emotional learning (SEL) in afterschool programs. It provides a brief history of the growing focus on SEL, along with a summary of remarks by national leaders.\nThis classic report clarifies the cost of quality out-of-school time programs, based on data from 111 quality programs in six cities. It provides the mean and range for hourly and daily cost per slot, with an analysis of factors that bring differences to cost.\nThis report offers important insights into how collaboration across sectors can help state and city systems build a more skilled, sustainable workforce that better supports children and youth.\nThis report discusses the components of strong continuous quality improvement systems, emphasizing ways to safeguard and sustain such systems. It shares lessons learned from afterschool quality system leaders who took part in a multi-year Wallace-funded initiative for cities.\nThis website offers afterschool nonprofits a range of tools, articles, reports, and resources to develop financial skills. It includes articles, webinars, videos, and self-assessment resources on planning, operations, monitoring, and governance.\nThis website provides links to all issues of Afterschool Matters, a national, peer-reviewed journal aimed at practitioners who develop and manage youth programs, as well as researchers and policymakers. The journal is published two to three times a year; each journal is 48-60 pages. Articles on almost any topic related to school-age care are available here.\nThis website provides resources on program planning, managing staff and volunteers, planning lessons, technology, and materials using a real-life, project-based approach to learning. The website includes sections on digital storytelling, inquiry-based learning, youth media training, fostering positive climates, and nurturing creativity.", "pred_label": "__label__POS", "pred_score_pos": 0.5364154577255249}
{"content": "Home Office & Smart Home\nCyber Security\nMany of small businesses and homes have been victims of cybercrime and have had their personal information, including bank details, compromised, or stolen without their knowledge.\nOne of the ways hackers can get into your system is through your router. They can also gain access through smart devices such as unsecured smart light bulbs, Wi-Fi baby monitors, smart watches and many other internet gadgets commonly found in homes or small offices.\nThese devices are clearly here to stay. However, hackers can and have been using these as a back door into people’s homes and personal data.", "pred_label": "__label__POS", "pred_score_pos": 0.9680057168006897}
{"content": "Motorists were speeding three times more frequently during lockdown compared to normal, according to new analysis by AX.\nThe study of telematics data by AX suggests motorists were making the most of unusually low traffic levels, giving drivers the opportunity to speed in otherwise normally congested areas.\nSerious speeding events – the most severe category of excessive speed – occurred every 136 miles on average in April, compared to every 443 miles in February.\nMajor speeding events were also significantly more frequent, taking place on average once every 32 miles in April, down from every 94 miles in February.\nIt wasn’t just a case of motorists covering shorter journeys either, with major speeding events occurring on average once every 4.3 trips in April compared to every 9.8 trips two months earlier.\nVan drivers, who played a crucial role during lockdown, proved to be much more obedient than car drivers, with telematics devices detecting major incidents twice as often as normal compared to four times as frequently for car drivers.\nIn normal circumstances, data suggests van drivers tend to commit more major speeding events than cars, whereas the reverse is true for serious events, largely due to the majority of cars offering more potent performance than most vans.\nAs lockdown restrictions began to ease, speeding also started to return to normal levels, with all types of speeding incident occurring almost half as frequently in June compared to April, although still far from pre-lockdown levels.", "pred_label": "__label__POS", "pred_score_pos": 0.9900297522544861}
{"content": "The United Nations turns 75 in 2020. This is indeed a time for celebration. The UN has helped maintain peace and security and lessen the casualties of war, played a critical role in the fight against AIDS and other diseases, feeds approximately 104 million people annually from 80 nations, and has convened a series of summit conferences to combat our growing climate crisis.\nWe now face threats that were unimaginable 75 years ago. Nuclear proliferation, climate change, mass migration, and terrorism are a daily occurrence. We need a new UN, capable of handling these challenges. CGS has partnered with organizations worldwide to use the occasion of the UN’s 75th anniversary to push for meaningful change. UN2020 and Together First are two organizations that are leading the way. We invite you to explore and get involved in this vital work.", "pred_label": "__label__POS", "pred_score_pos": 0.9984197020530701}
{"content": "HEALTHY HOLIDAY RECIPES Nurture your consortium with Octo-nutty goodness.\nA meal before the meal? These recipes are so tasty you'll need to remind yourself to save room for the main course.\nWe went a little nuts with these updates to the classics. There's no need for anyone to know they've got a healthy spin — that'll be our little secret.\nWho needs another take on the classic pumpkin pie? These recipes give you additional options that are simple to make and hard to resist.\nHEALTH NUTS, HEALTHY NUTS Gluten-free, Paleo, Whole30, Keto or vegan? We've got you covered — with 8 arms!\nPaleo recipes exclude dairy, grain, and processed food while focusing on nutrients from plant and animal proteins, vegetables, and fruit.\nThe Whole30 lifestyle emphasizes whole foods and healthy proteins, eliminating sugar, alcohol, grains, legumes, soy, and dairy.\nA vegan diet excludes all animal-derived foods including eggs, dairy, meat, and fish. Plant-based proteins are a must-have for vegans.\nThe ketogenic diet is a high-fat, adequate-protein, low-carb diet that forces the body to burn fats rather than carbohydrates.\nGluten-free eating is helpful for treating Celiac Disease and GI issues. It eliminates the gluten proteins found in wheat and related grains.\nYou can't spell nutrition without NUT, right? Whatever your dietary needs or preferences, you can't go wrong with these tasty recipes.", "pred_label": "__label__POS", "pred_score_pos": 0.9208642244338989}
{"content": "Abstract\nWe developed a novel delay discounting task to investigate outcome impulsivity in pigs. As impulsivity can affect aggression, and might also relate to proactive and reactive coping styles, eight proactive (HR) and eight reactive (LR) pigs identified in a manual restraint test (\"Backtest\", after Bolhuis et al., 2003) were weaned and mixed in four pens of four unfamiliar pigs, so that each pen had two HR and two LR pigs, and aggression was scored in the 9h after mixing. In the delay discounting task, each pig chose between two levers, one always delivering a small immediate reward, the other a large delayed reward with daily increasing delays, impulsive individuals being the ones discounting the value of the large reward quicker. Two novel strategies emerged: some pigs gradually switched their preference towards the small reward ('Switchers') as predicted, but others persistently preferred the large reward until they stopped making choices ('Omitters'). Outcome impulsivity itself was unrelated to these strategies, to urinary serotonin metabolite (5-HIAA) or dopamine metabolite (HVA) levels, aggression at weaning, or coping style. However, HVA was relatively higher in Omitters than Switchers, and positively correlated with behavioural measures of indecisiveness and frustration during choosing. The delay discounting task thus revealed two response strategies that seemed to be related to the activity of the dopamine system and might indicate a difference in execution, rather than outcome, impulsivity.", "pred_label": "__label__POS", "pred_score_pos": 0.588184118270874}
{"content": "Abstract\nThe last decade has seen declining numbers of students studying modern foreign languages at degree level, and university language departments are experiencing serious falls in recruitment (CILT, 2000). This inquiry, conducted during The European Year of Languages (2001) and using predominantly qualitative research methods, aimed to provide some initial data on why students are not studying for MFL degrees. Data were collected in five stages involving research interviews (both group and individual) and a small-scale questionnaire from the following populations: selected university undergraduates; selected sixth-formers in both a state-sector and a private-sector school; two heads of modern languages in the school sector; two modern language programme leaders in the university sector. Whilst any conclusions drawn from this study are not generalisable, two key factors emerged from the students' responses. These were a general climate of negativity surrounding perceptions of (degree-level) modern foreign language study, and a negative A level experience. Four broad themes emerged from the interviews with staff members. These were: the teaching of modern foreign languages in secondary (and primary) schools; a general ‘climate of negativity’ pervading wider society; vocational concerns on the part of students; and professional roles and practice.\nOriginal language English Pages (from-to) 59-67 Number of pages 9 Journal Language Learning Journal Volume 2 Issue number 29 Publication status Published - 2004", "pred_label": "__label__POS", "pred_score_pos": 0.5442522764205933}
{"content": "I know the coronavirus is first and foremost on everyone's mind, and I want you to know I'm here and will continue to update you as needed. I hope you are doing well and taking good care of yourself. If…\nI know you’re all concerned about the coronavirus, and I’ll keep updating you on that as needed. If you missed my email yesterday on what I've learned about the coronavirus and how I can support you during this time, be…\nWow. As you all know, the coronavirus situation has really grown. For weeks now, I have been confused by it. All the fear just didn't make sense when compared to the number of people affected. In the U.S. the number…\nEvery day we're hearing about the coronavirus in the news, and I know many of you are concerned. I'm here to reassure you and let you know what you can do to protect yourself. The reason the coronavirus is such…\nToday I'm talking about one of my very favorite topics, perimenopause. I've just gone through perimenopause myself, and now I'm officially in menopause - woohoo! I know firsthand how tricky this transition time can be. A few years ago, I…\nI hope your 2020 is off to a good start! For me it's been a wild ride so far, and I'm excited to see what lies ahead. I'm back with my hormone series, and today we're talking about the fertility…\nRecently I did something that took a LOT of courage. Honestly, I still can't believe I did it! I wrote a song, recorded it, AND performed it - yes, in front of people!! This was huge for me. I'm not…\nHave you heard of xenoestrogens? If not, please listen up. This is a HUGE problem we're all facing, no matter our age or gender. Xenoestrogens are chemicals that are acting as estrogen in our systems and severely disrupting our natural…\nThe transition into puberty & womanhood can be pretty tricky, as you may remember. :) Many girls are experiencing things like menstrual cramps, fatigue, and weight gain, not to mention the emotional ups & downs. It can be a really…\nPlease forgive my absence! I've been a busy lady these past couple of months. I traveled to Australia for a Mediherb speakers conference, then headed to Niagra Falls for a Joe Dispenza Advanced Meditation retreat. In the midst of all…", "pred_label": "__label__POS", "pred_score_pos": 0.6732361316680908}
{"content": "Despite popular tradition, we know that Jesus was likely not resurrected early on Sunday morning following His crucifixion, because scripture tells us that when the women went to the tomb ‘very early in the morning,’ the angels told them,\n“He is not here; he has [already] risen!” (Luke 24:6).\nSo when exactly was Jesus resurrected?\nDespite what church tradition would have us believe, a proper analysis of scripture makes clear that Jesus was\nnot crucified on Friday and did not rise on a Sunday morning in AD 30. According to scripture and the Jewish calendar for the year of Jesus’ crucifixion, Jesus fulfilled the Spring Feasts of the Lord (Leviticus 23) at His first coming; he fulfilled Passover with His crucifixion; He fulfilled the Feast of Unleavened Bread with His burial; and He fulfilled First Fruits with His resurrection.\nIt is especially significant that the Jewish\nFeast of First Fruits was observed on the day following the weekly Sabbath of the Passion Week – on Sunday. According to Jewish tradition, all days began at sundown; therefore, . Jesus’ resurrection must therefore have occurred at some point during that period. And since we have already established that it was First Fruits began at sundown of Saturday and ended on sundown of Sunday beforeearly morning on Sunday, when did it actually occur?\nJesus specifically stated that – like Jonah – He would be in the heart of the earth for\n(Jonah 1:17, Matthew 12:40). Unfortunately, church tradition – which advocates a Friday afternoon crucifixion, a burial before sunset, and a resurrection on Sunday morning -simply would not allow for the scripturally-required three days and three nights three days and three nights – even if we allow for partial days and nights.\nI believe that in order for Jesus’ Passion to have properly fulfilled scripture and the traditions of the Jewish Feasts, the crucifixion must have occurred on Wednesday afternoon. Burial would have followed at sundown (the beginning of Thursday and the\nFeast of Unleavened Bread); and the resurrection would have occurred at sundown on Saturday, the start of First Fruits and the beginning of Sunday on the Jewish calendar. This chronology provides three full days and three full nights for Jesus’ body to be in the earth.\nBecause Jesus served as the\nFirst Fruits of the resurrection, it makes sense that He would have been resurrected at the start of First Fruits, which would also have corresponded to the Jewish rite of First Fruits, during which the Temple Priests offered to heaven the first cuts of barley from a special field in the Kidron Valley. This would have been the exact moment at which Jesus rose from the grave.\nGod makes all things perfect. What could have been more perfect than this?\nFor a complete discussion of the\nof Jesus’ death, resurrection, and ascension(s), please read the various postings at the following link on the when website: Truth in Scripture", "pred_label": "__label__POS", "pred_score_pos": 0.7268953323364258}
{"content": "A Class I medical device recall has been issued by Medtronic for certain HeartWare Ventricular Assist Device (HVAD) cardiac devices, after the manufacturer recognized that a screw may break or tear during assembly before it is implanted, resulting in a delay in treatment that could cause serious and potentially life threatening complications.\nThe Medtronic HeartWare HVAD recall was announced by the FDA on May 28, following nearly 100 reports of problems where the strain relief screw broke and outflow graft tore while preparing the device for implant. To date, no deaths have been associated with the impacted products, but the class I designation indicates that continued use of the product may result in severe adverse events.\nThe HeartWare Ventricular Assist Device (HVAD) is a pump that helps the heart deliver blood to the rest of an individual’s body, and is typically used as a bridge to cardiac transplant for patients at risk of left ventricular heart failure. It is used on patients both in the hospital and out of the facility, such as when a patient is being transported via aircraft or helicopter.\nAccording to the recall, the Medtronic HVAD contains a defect that may allow the outflow graft of the Pump to tear and the strain relief screw to break during assembly, prior to implant. Officials have indicated these defects may not be identified during or after they are attached to the HVAD pump, which may result in failure to perform and delay life-saving treatment.\nThe problem places patients at risk of suffering serious injuries, including dizziness, loss of consciousness, bleeding, fluid buildup around the heart, the need for additional medical procedures and death.\nThe recall impacts at least 4,924 HeartWare HVAD Pump Outflow Graft and Outflow Graft Strain Relief systems with model numbers 1125, 1103 and 1153 manufactured by Medtronic and distributed to medical facilities across the U.S. from March 1, 2018 to April 1, 2020.\nMedtronic initiated the recall on April 3, 2020 and issued a Medical Device Safety Alert to all affected customers, instructing them to closely inspect the graft after assembly and before implantation and to practice standard pre-operative and immediate post-operative patient management to look for this issue.\nAfter receiving 92 reports of the strain relief screw breaking or the outflow graft tearing, the FDA upgraded the Medical Device Safety Alert to a Class I recall, indicating it is the most serious of its kind, and that a risk of serious injury or death could result from the use of the products.\nCustomers with impacted devices are being asked to complete a Physician Confirmation Form sent on April 3, 2020, and either return it to your Field Representative or email to RS.CFQFCA@medtronic.com to indicate you received the notification.\nMedtronic has experienced a variety of issues with HeartWare HVAD models, resulting in at least two recalls in recent years. In 2018, Medtronic issued a HeartWare HVAD recall involving more than 16,000 devices after discovering the electrical connection between the system’s power source, such as the battery, AC adapter, or DC adapter, and the HVAD controller could be interrupted. Officials warned this may cause the pump to stop working, resulting in an exacerbation of heart failure symptoms, including weakness, dizziness, anxiety, nausea, loss of consciousness or death.\nIn 2017, Medtronic issued another Class I recall for HVAD System Controllers due to the devices experiencing battery failure, power and data failures, and premature wearing of the alignment guides. That recall resulted in at least two deaths, four serious injuries and 27 field reports of other failures and problems regarding the devices.", "pred_label": "__label__POS", "pred_score_pos": 0.5924634337425232}
{"content": "In this age of rapid digitization and automation, the popularity of ICT education at most universities has evidently skyrocketed. With an increasing number of students studying CS courses, the workload for educators has also increased significantly. Because of this, we often observe a pattern across universities wherein educators only conduct a final examination at the end of the course rather than have assignments periodically throughout the course duration. Teachers rightly point out that they do so primarily because they simply lack resources and time to examine a large number of student submissions and provide feedback individually.\nStudents note that the lack of formative assessment with feedback does not help much with the learning process and is often discouraging for newcomers. For instance, at the University of Edinburgh, Dr Volker Seeker has been teaching ‘Introduction to Object Oriented Programming’ for a couple years and he mentions that they traditionally only had a final exam for this course because of the difficulty involved in providing feedback to everyone and the lack of efficient tools to check for plagiarism on the Java code. This final exam created a strong sense of dissatisfaction among students, especially for beginners, since they only had a limited time of 2 hours to solve the programming exercises. This was clearly discouraging particularly for students who were keen on learning programming skills and would have preferred to receive feedback regularly.", "pred_label": "__label__POS", "pred_score_pos": 0.5480395555496216}
{"content": "Imagine a world where we become micro-generators of clean, renewable solar power in a connected and resilient micro-grid.\nThis possibility is now becoming a reality with Hydro Ottawa's\nMiGen Transactive Grid. MiGen enables consumers and businesses to help shape the future of the electricity grid by establishing micro-grids. These allow participants to generate their own solar power, store electricity, share with connected neighbours, and send unused electricity back to the grid.\nRead more on\nhttps://mailchi.mp/hydroottawa/hydro-ottawa-bia-update-newsletter-1917577?e=844f4b6ab2", "pred_label": "__label__POS", "pred_score_pos": 0.9956865310668945}
{"content": "For four decades, the team at Hord Coplan Macht (HCM) has provided expert design services to healthcare and educational institutions, nursing schools among them, across the country to help them meet current needs while offering flexibility for the future.\nRecognizing the unique set of challenges nursing/allied health educators and administrators are currently facing, we are creating resources to offer insight into the evolving nursing profession, how educators are addressing this evolution and the pallet of learning spaces needed to prepare nursing students for the future profession.\nTopics covered in this whitepaper include:\nEvolving Healthcare Environment Changing Demographics in Nursing Active Learning Spaces Enhance Outcomes Implications Of These Trends For Nursing Education Facilities Design Considerations + Solutions", "pred_label": "__label__POS", "pred_score_pos": 0.9943543672561646}
{"content": "Abstract\nParticle suspensions, present in many natural and industrial settings, typically contain aggregates or other microstructures that can complicate macroscopic flow behaviors and damage processing equipment. Recent work found that applying uniform periodic shear near a critical transition can reduce fluctuations in the particle concentration across all length scales, leading to a hyperuniform state. However, this strategy for homogenization requires fine tuning of the strain amplitude. Here we show that in a model of sedimenting particles under periodic shear, there is a well-defined regime at low sedimentation speed where hyperuniform scaling automatically occurs. Our simulations and theoretical arguments show that the homogenization extends up to a finite length scale that diverges as the sedimentation speed approaches zero.\nASJC Scopus subject areas Chemistry(all) Biochemistry, Genetics and Molecular Biology(all) Physics and Astronomy(all)", "pred_label": "__label__POS", "pred_score_pos": 0.7682325839996338}
{"content": "Abstract\nAccording to attentional control theory (ACT; Eysenck et al. in Emotion 7(2):336–353, 2007) anxious individuals recruit motivation on demanding tasks, which helps prevent performance shortfalls. We used a quasi-experimental design to examine the relationship between trait anxiety (operationalised using questionnaire scores), situational stress (manipulated using ego threat instructions) and motivation (indexed using a self-report goal-commitment scale) in predicting effectiveness (accuracy) and efficiency (accuracy divided by RT) on the reading span task. After controlling for depression, the variables were not related to effectiveness; however there was a significant trait anxiety × goal-commitment interaction on reading span efficiency. Higher trait anxiety predicted better efficiency at higher goal-commitment, and poorer efficiency at lower goal-commitment, and these relationships were independent of situational stress. Results are interpreted in terms of ACT.", "pred_label": "__label__POS", "pred_score_pos": 0.9571089148521423}
{"content": "the call protection period. Interest rates could potentially fall to the point where it would be beneficial for the company to call the bond, yet the company is unable to do so. 6. A make-whole call provision should lower the coupon rate in comparison to a call provision with specific dates since the make-whole call repays the bondholder the present value of the future cash flows. However, a make-whole call provision should not affect the coupon rate in comparison to a plain vanilla bond. Since the bondholders are made whole, they should be indifferent between a plain vanilla bond and a make-whole bond. If a bond with a make-whole provision is called, bondholders receive the market value of the bond, which they can reinvest in another bond with similar characteristics. If we compare this to a bond with a specific call price, investors rarely receive the full market value of the future cash flows.\n7. A positive covenant would reduce the coupon rate. The presence of positive covenants protects bondholders by forcing the company to undertake actions that benefit bondholders. Examples of positive covenants would be: the company must maintain audited financial statements; the company must maintain a minimum specified level of working capital or a minimum specified current ratio; the company must maintain any collateral in good working order. The negative side\nYou've reached the end of your free preview.\nWant to read all 3 pages?", "pred_label": "__label__POS", "pred_score_pos": 0.8974531292915344}
{"content": "R3 Report Issue 24: PC Standards for Maternal Safety\nEffective July 1, 2020, 13 new elements of performance (EPs) will be applicable to Joint Commission-accredited hospitals. These new requirements are within the Provision of Care, Treatment, and Services (PC) chapter at PC.06.01.01 and PC.06.01.03 and are designed to improve the quality and safety of care provided to women during all stages of pregnancy and postpartum. The United States ranks 65th among industrialized nations in terms of maternal death. Because of worsening maternal morbidity and mortality, The Joint Commission evaluated expert literature to determine what areas held the most potential impact. The literature review revealed that prevention, early recognition, and timely treatment for maternal hemorrhage and severe hypertension/preeclampsia had the highest impact in states working on decreasing maternal complications. This approach was supported by a technical advisory panel assembled by The Joint Commission, resulting in the development of EPs that focus on these complications.", "pred_label": "__label__POS", "pred_score_pos": 0.5368866920471191}
{"content": "Comparing rates and characteristics of harms across different pharmaceutical opioids: an examination of Australian ambulance attendances 2013-2018. Abstract Background. Similar to other high-income countries, Australian opioid-related mortality has almost doubled in the past decade, and the majority of the deaths are pharmaceutical opioid-related. Despite common extramedical use, few studies examine the relative harms associated with different pharmaceutical opioids. Aims. This study aimed to describe rates and characteristics of ambulance attendances related to nine commonly prescribed pharmaceutical opioids: buprenorphine, codeine, fentanyl, oxycodone, oxycodone-naloxone, morphine, pethidine, tramadol, and tapentadol. Method: Trained research assistants coded clinical records of ambulance attendances from January 2013 to September 2018. Cases were included where recent extramedical (i.e. over- or inappropriate) use of a pharmaceutical opioid significantly contributed to the reason for the ambulance attendance.\nWe examined supply-adjusted rates of attendances using Poisson regression and used multinomial logistic regression to compare severity and other characteristics of attendances associated with different pharmaceutical opioids in Victoria (Australia’s second largest state), and compared these to the other jurisdictions of Australia.\nResults. We identified 14 161 ambulance attendances relating to extramedical use of pharmaceutical-opioids. In Victoria, the highest rates of attendance (per 100 000 mg OME) were for codeine (0.273/100 000) and oxycodone (0.113/100 000). The lowest rates were for fentanyl (0.019/100 000) and tapentadol (0.005/100 000). Rates of oxycodone-naloxone-related attendances (0.031/100 000) were lower than for oxycodone as a single ingredient (0.113/100 000).\nFentanyl-related attendances were the most severe, most likely to be an accidental overdose and have naloxone administered, and least likely to be transferred to hospital. In contrast, codeine-related attendances were more likely to involve co-morbid suicidal thoughts or behaviours, involve younger females and require transport to hospital for further care.\nDespite significant changes in the volume of supply for different opioids over the study period, rates of supply-adjusted harm remain relatively stable. Data from states outside Victoria were broadly consistent.\nDiscussion. This study represents one of the most detailed population level examinations of pharmaceutical opioid-related harm in Australia. Distinct patterns of harms were observed for different opioids. These highlight the need to consider factors such as the formulation, to develop nuanced responses to reduce pharmaceutical opioid-related harm, particularly as newer formulations are introduced. Furthermore, policy attention has largely focused on accidental overdose, with less consideration of interventions aimed at intentional harm. Policy makers may consider the role of regulation in addressing harms from pharmaceutical self-poisoning.", "pred_label": "__label__POS", "pred_score_pos": 0.9021216630935669}
{"content": "Sudden obstetric collapse is a rare but a potentially life-threatening event, it is a sudden event involving the cardio-respiratory systems and /or the brain resulting in an absent or reduced conscious level and potentially death, at any stage up to 6 weeks of delivery.Dr. Alpesh Gandhi, Consultant Obstetrician and Gynaecologist discusses the immediate management which involves resuscitation of the patient (assessment, CPR, basic and advanced life support, cardioversion). He discusses the decision making in emergency Caesarean section in cardiac arrest and perimortem Caesarean section. The various causes of sudden obstetric collapse, and the differential diagnosis and the salient points pertaining to vasovagal shock, sudden uterine inversion, sepsis, septic shock, acute pulmonary oedema and amniotic fluid embolism are discussed at length.", "pred_label": "__label__POS", "pred_score_pos": 0.945712149143219}
{"content": "Crowd Connected’s multi-faceted Colocator platform was successfully deployed to monitor and engage with fans of Real Madrid and Juventus for the UEFA Champions League Final – Europe’s premier club football match – which took place at the beginning of June 2017 at the National Stadium of Wales in Cardiff. Meeting the Business Need\nSteer Davies Gleave (SDG), an independent global consultancy that combines commercial, economic, technical and planning expertise, was contracted by the Football Association of Wales to engage football fans in a dynamic fashion as they travelled to and from the UEFA Champions League final. The match was played in Cardiff, a location unfamiliar to the vast majority of the travelling supporters. It was estimated that well over 170,000 Italian and Spanish fans would descend on the Welsh capital for their respective clubs’ biggest game of the season – significantly more than the stadium’s official total seating capacity of 74,500. The solution\nIn an atmosphere of heightened security concerns, organisers were seeking ways to: Engage with the travelling supporters of each club in a cutting-edge way, keeping them informed and up to date; Monitor, log and understand in real time the movement of fans both as they travelled to the stadium pre-match and as they left after the game; Showcase an enhanced digital experience which combined seamlessly with the physical; and Encourage fans to see more of Cardiff thereby spreading demand.\nTapping into their experience and track record from both the London 2012 Olympics and the 2015 Rugby World Cup, SDG developed a specific event mobility app, designed to provide fans with a personalised ‘guide in their pocket’. Supporters of both teams were encouraged to download this dedicated app before they even began travelling across Europe to the game.\nThe Solution\nSDG turned to Crowd Connected and our market-leading location intelligence to underpin the delivery of three significant component elements of their solution:\nreal-time location data harvesting, processing and visualisation to provide unrivalled situational awareness; highly targeted geo-behavioural communications to fans; and granular post-event analytics.\nCrowd Connected’s Colocator SDK was embedded into the SDG-developed app. Without requiring any additional hardware, data from mobile phones with this app installed was transmitted to the cloud-based Colocator platform, where it was stream processed in real time to ‘digitise the physical’.\nThe Results\nUsing the Insight module within the intuitive web-based Colocator console, SDG provided control rooms in multiple location with customised visualisation of fan movement in qualitative and quantitative form via configurable heatmaps and dashboards.\nThis delivered never-seen-before\nlive readouts of vital information such as journey times, fan densities and queue times. It enabled, at a glance, those who needed the information to see, for example, how fans’ actual travel patterns were deviating from the planned and/or predicted behaviour.\nThis awareness of aggregated travel trends began even before supporters reached the UK. And it provided a single source of truth for understanding behaviour across multiple transport modes.\nSDG also extensively used the Engage module for its unbeatable\ngeo-targeted messaging capability. Engage enabled SDG to build sophisticated communication campaigns to fans who had downloaded the app, providing real-time audience segmentation based on any combination of historic and present location. As a result, by Integrating Crowd Connected’s Colocotor technology with Urban Airship’s push message delivery system, SDG were able to deliver a large number of highly targeted push notification messages.\nOver 50 different messages were sent, composed in multiple languages (Spanish, Italian and English), engaging with fans from three weeks before the match. Examples included highly targeted logistics advisories relevant only to certain segments of fans (by club, by mode of transport, by current and historic location, etc), messages promoting specific attractions citywide in Cardiff, and advisories re match-specific arrangements.\nMoreover, the effectiveness of certain push-notifications recommending a particular course of action could be evaluated by analysing the subsequent movement of app users who had been targeted with that message.\nFinally, SDG relied on the app user location data provided by Crowd Connected to deliver a\npost-event wrap-up based on hard evidence – normally only captured through expensive survey methodologies.\nCrowd Connected’s Colocator technology was instrumental to us making people think differently about how to engage fans and influence their behaviour. We’re delighted with the results and are very excited by the prospect of working closely with Crowd Connected on future projects.Russ Yell – Head of Digital Intelligence, SDG", "pred_label": "__label__POS", "pred_score_pos": 0.600589394569397}
{"content": "UK aid’s approach to youth employment in the Middle East and North Africa\nA full review assessing the relevance and effectiveness of UK aid programmes in promoting employment opportunities for young people across the Middle East and North Africa (MENA).\nBackground\nOver half of the population in the MENA region is under 24 years old and a quarter of young people in the labour force are unemployed. Some countries within the region report that up to 60% of young women are not in education, employment or training (NEET), whilst nearly 30% of young unemployed people across the region have a university degree.\nThe youth employment challenge is exacerbated by both demand-side failures, such as a lack of access to finance, restrictive business regulations and cronyism which reduces the number of employment opportunities, and supply-side failures, such as education and skills that do not match labour market needs, making it harder for young people to compete for jobs.\nOverall, the MENA region is characterised by economic and geopolitical instability. Economies face structural imbalances including large, inefficient public sectors, uncompetitive business environments and governance challenges, as well as high youth unemployment.\nWithin this context, sustainable economic development and poverty reduction in the region are closely linked to the need to create decent work opportunities for young people.\nScope\nThe range of potential interventions to address youth unemployment is broad. We have identified 115 programmes with a total value of over £2.4 billion from the UK’s aid portfolio in the region that include a youth employment element within the scope of our review.\nThe portfolio under review includes programmes where youth employment is a direct objective, or where youth employment is a component of other objectives, such as in programmes that promote stability or support refugee populations.\nThe portfolio covers Iraq, Jordan, Lebanon, the Occupied Palestinian Territories (OPTs), Syria, Turkey, Yemen, Algeria, Egypt, Libya, Morocco and Tunisia, and includes programming since the publication of the 2015 UK aid strategy.\nReview questions Relevance:Is the UK’s approach to promoting youth employment in MENA relevant to needs? Coherence:How coherent is UK aid’s approach to promoting youth employment? Effectiveness:How effective is the UK’s support to youth employment in MENA? Timeline\nResearch for this review began in September 2020, with publication expected in June 2021.", "pred_label": "__label__POS", "pred_score_pos": 0.6270846128463745}
{"content": "Pregnancy outcomes in women with lupus significantly improved in last 18 years\nHealio Primary Care reports on the findings of an HSS study published in the\nAnnals of Internal Medicine which demonstrated maternal mortality significantly decreased and overall pregnancy outcomes improved in women with systemic lupus erythematosus (SLE).\nLead study author Bella Mehta, MBBS, MD, MS, rheumatologist at HSS, and colleagues, conducted a retrospective cohort study using discharge data from the National Inpatient Sample database to evaluate trends and fetal complications in SLE patients from 1998-2015. Outcomes including in-hospital maternal mortality, fetal mortality, non-delivery-related hospital admissions, preeclampsia or eclampsia, cesarean sections, and the length of stay were evaluated and compared in pregnant women with and without SLE.\nResearchers noted that the significantly larger improvement in maternal mortality among women with SLE compared with those without SLE suggests that factors beyond developments in obstetrics were responsible for improved maternal mortality in those with SLE.\nRead the full article at Healio.com.", "pred_label": "__label__POS", "pred_score_pos": 0.9913796186447144}
{"content": "Breath is life force, Spirit moving into and through us. When we breathe, life flows through us.\nWe all want to feel vital, alive, peaceful and full of purpose. When we breathe consciously and purposefully, we release nervous energy, anxiety, fear and stress and breathe in peace, purpose, love, and compassion.\nWhen we breathe, we release our hectic pace and claim peace. We slow our minds and bring our focus back to the present moment so that we can perceive and act from a more balanced place.\nIn recent weeks the world has again become a scarier place – we again witness terrorist attacks resulting in death, disruption and fear. It’s in times like this our gratitude practices help us remember the truth we know – that love, compassion, and peace are the powers that sustain us and that ultimately prevail. Gratitude is the first step in opening our hearts to this truth, even in challenging times.\nRev. Sydney’s message focuses on expressing appreciation with meaning, using the tools of nonviolent communication. How do you turn a comment such as “Good job!” into an expression of detailed appreciation that lets the listener know what his or her effort meant to you? Learn how expressing appreciation more deeply can create meaningful connection in your life!", "pred_label": "__label__POS", "pred_score_pos": 0.9358351826667786}
{"content": "摘要\nYoung incipient species provide ideal materials for untangling the process of ecological speciation in the presence of gene flow. The Miscanthus floridulus/sinensis complex exhibits diverse phenotypic and ecological differences despite recent divergence (approximately 1.59 million years ago). To elucidate the process of genetic differentiation during early stages of ecological speciation, we analyzed genomic divergence in the Miscanthus complex using 72 randomly selected genes from a newly assembled transcriptome. In this study, rampant gene flow was detected between species, estimated as M = 3.36 × 10\n-9 to 1.20 × 10 -6, resulting in contradicting phylogenies across loci. Nevertheless, beast analyses revealed the species identity and the effects of extrinsic cohesive forces that counteracted the non-stop introgression. As expected, early in speciation with gene flow, only 3-13 loci were highly diverged; two to five outliers (approximately 2.78-6.94% of the genome) were characterized by strong linkage disequilibrium, and asymmetrically distributed among ecotypes, indicating footprints of diversifying selection. In conclusion, ecological speciation of incipient species of Miscanthus probably followed the parapatric model, whereas allopatric speciation cannot be completely ruled out, especially between the geographically isolated northern and southern M. sinensis, for which no significant gene flow across oceanic barriers was detected. Divergence between local ecotypes in early-stage speciation began at a few genomic regions under the influence of natural selection and divergence hitchhiking that overcame gene flow. All Science Journal Classification (ASJC) codes Genetics Plant Science Cell Biology", "pred_label": "__label__POS", "pred_score_pos": 0.7490838170051575}
{"content": "How can manufacturers grow profits by designing, selling and producing personalized products? Manufacturers have significantly increased the level of personalization in their products over the past five years, and customization will accelerate over the next five. Why? Companies across the manufacturing industries recognize that tailoring products drives increased differentiation, higher sales, and better margins. How", "pred_label": "__label__POS", "pred_score_pos": 0.5596605539321899}
{"content": "160 Gould Street\nSuite 310\nNeedham,\nMA\n02494\nOver time, the term Wealth Management has come to be used interchangeably with that of Investment Management. Historically, Investment Management has been defined as the selection, appropriate allocation and continuous management of financial assets. A search for ‘Wealth Management’ will highlight many resources offering ‘Investment Management’; but few are representative of a comprehensive Wealth Management philosophy.\nAt The Bulfinch Group, we believe Wealth Management should be far more than a well-designed investment selection and a discussion focused on rates of return. The Bulfinch Group has redefined Wealth Management by creating a Protection-First Planning Methodology to help safeguard wealth and provide for each client’s unique financial situation. Our Advisors utilize a client-centric approach, first preserving income and cash flow as the foundation of the wealth management process. Investment management, estate planning, tax strategies, retirement planning, college savings, and ongoing cash flow protection are all additional components of the coordinated, integrated and cohesive wealth management methodology.", "pred_label": "__label__POS", "pred_score_pos": 0.7765698432922363}
{"content": "What is the Local Government Benchmarking Framework?\nThe LGBF is a high-level benchmarking tool designed to support senior management teams and elected members to ask questions about key council services.\nIt reflects a commitment by SOLACE (Scotland) and COSLA to develop better measurement and comparable data as a catalyst for improving services, targeting resources to areas of greatest impact and enhancing public accountability.\nThe framework provides high-level 'can openers' which are designed to focus questions on why variations in cost and performance are occurring between similar councils. They do not supply the answers. That happens as councils engage with each other to ‘drill down’ and explore why these variations are happening.\nThe LGBF helps councils compare their performance against a suite of efficiency, output and outcome indicators that cover all areas of local government activity. The framework now has 8 years of data. Publication of the LGBF forms part of each council’s statutory requirements for public performance reporting, replacing the previous SPI regime.\nData for all councils can be found on the Improvement Service site.", "pred_label": "__label__POS", "pred_score_pos": 0.9017418026924133}
{"content": "Glossary Data Virtualization\nData virtualization delivers a unified, simplified view of an organization’s data that can be accessed anytime. It integrates data from multiple sources, to create a single data layer to support multiple layers and users. The result is faster access to this data, providing instant access, any way you want it.\nData virtualization involves abstracting, transforming, federating and delivering data from disparate sources. This allows users to access the applications without having to know their exact location.\nThere are some important advantages to data virtualization: An organization can gain business insights by leveraging all data They can become aware of analytics and business intelligence Data virtualization can streamline an organization’s data management approach, which reduces complexity and saves money\nData virtualization involves three key steps. First, data virtualization software is installed on-premise or in the cloud, which collects data from production sources and stays synchronized as those sources change over time. Next, administrators are able to secure, archive, replicate, and transform data using the data virtualization platform as a single point of control. Last, it allows users to provision virtual copies of the data that consume significantly less storage than physical copies.\nSome use cases for data virtualization are: Application development Backup and disaster recovery Datacenter migration Test data management Packaged application projects", "pred_label": "__label__POS", "pred_score_pos": 0.7071060538291931}
{"content": "The United States is no stranger to deadly natural disasters. Natural disasters can occur in various forms and at any time. While you cannot predict everything, there are measures that can minimize the damage that incurs.\nBetween 2010 and mid-2019, major storms and climate-related events caused a total of $761 billion in damage and killed nearly 5,200 people in the United States.\nA natural disaster is a major adverse event resulting from natural processes of the Earth; examples include floods, hurricanes, tornadoes, volcanic eruptions, earthquakes, tsunamis, and other geologic processes.\nGet a free quote now or ask us a question,it’s free, simple and fast. GET A QUOTE", "pred_label": "__label__POS", "pred_score_pos": 0.5057506561279297}
{"content": "You may have heard about genetically modified organisms (GMOs) along with predictions of dire consequences for the planet or claims the technology is necessary to feed the Earth’s growing population. At the April edition of Beer with a Scientist, Paul Vincelli, PhD, professor in the Department of Plant Pathology at the University of Kentucky College of Agriculture, Food and Environment, will set the record straight with peer-reviewed science.\nVincelli will make the trip across I-64 to share his expertise on the scientific understanding of GMOs based on the substantial body of scientific literature. He will explain exactly what constitutes a genetically engineered crop, whether eating recombinant DNA is safe, and why scientists would want to change a plant’s genes in the first place.\nAt UK, Vincelli serves as coordinator for the United States Department of Agriculture (USDA) Sustainable Agriculture Research and Education Program. He provides science-based outreach on risks and benefits of genetically engineered crops in Kentucky, the nation and internationally.\nThe program begins at 8 p.m. on Wednesday, April 13 at Against the Grain Brewery, 401 E. Main St. A 30-minute presentation will be followed by an informal Q&A session.", "pred_label": "__label__POS", "pred_score_pos": 0.5781087875366211}
{"content": "By definition, a small business is typically a flat, centralized organization. The founder/owner is the boss and makes all the critical decisions. However, as the personnel count grows, the firm’s structure typically expands either horizontally (flat) or vertically (tall). Again, various factors including the owner’s management style, might affect what type of structure a business assumes.\nYou are here Flat versus tall organizations\n6841\nFront Matter Body Matter The mind of the entrepreneur: Your entrepreneurial journey begins by embarking on your own hero’s journey! Back Matter", "pred_label": "__label__POS", "pred_score_pos": 0.9527120590209961}
{"content": "Optimising haemodynamics in complex stented arteries\nGrant number: LP150100233 | Funding period: 2016 - 2020\nActive\nAbstract\nThis project aims to optimise the hemodynamics (blood flow) in coronary arteries with high curvatures and bifurcations. Experience has shown that the build-up of plaque — and the resulting occlusion of blood flow — tends to occur in these complex arterial regions. The most common therapeutic strategy is the insertion of a stent to prop open the artery. However, the nature of the geometry often leads to post-stenting complications such as restenosis and thrombosis, ultimately resulting in negative outcomes. In this project, advanced research methods from fluid dynamics and optimisation and control will be used to potentially minimise these highly undesirable effects.", "pred_label": "__label__POS", "pred_score_pos": 0.9995263814926147}
{"content": "Understanding the Key Role of NSPases in Early Broiler Nutrition\nThe early nutrition of broilers plays a key role in their lifetime productivity as in this intensive growth period the gastrointestinal tract (GIT) is under development. Alongside efficient nutrient utilisation, a healthy gut will support a robust immune system. It is widely accepted that maintenance or improvement of gut health is essential for optimum growth, better feed efficiency and overall health.", "pred_label": "__label__POS", "pred_score_pos": 0.9966465830802917}
{"content": "The role of internal audit continues to evolve, driven by many factors including economic conditions, globalization, and new, emerging risks. These scenarios are creating a dynamic environment and new opportunities for internal auditors to demonstrate its value. Internal auditors must create value for the business.\nPHAM CONSULT’s internal audit professionals bring the right mix of internal audit experience, industry specific knowledge and highly technical specialized skill sets. We can help your enterprise:\n– Improves the performance of the internal audit function so that it provides sufficient comfort to the Audit Committee or the Board of Supervisors.\n– Ensures that the internal audit team tackling the right risks, as well as improving and aligning the enterprise’s governance, risk and control frameworks. – Provides independent advice to the Board of Directors, the Audit Committee or the Board of Supervisors, management on the enterprise’s organizational risks and the state of the enterprise’s control.", "pred_label": "__label__POS", "pred_score_pos": 0.6340497732162476}
{"content": "As a former college student undertaking an assistant professor apprenticeship, it came as a surprise to me when I realized that it is quite a challenging experience having to deal with my more than 20 English composition students while I serve as a masters students myself. The task has provided me with opportunities for identifying the various issues affecting students in their academic life while comparing it with that of other well-established individuals in different careers. Upon starting dealing with the students, for instance, I had high expectations of them and quite idealistic that they would perform their level best. I approached the profession in a noble manner believing that I would manage to make a significant difference in the young individualss lives who shows minimal interest in literature as well as lacked the capacity to express them opinions in writing. Due to my mynervousness in my initial days with the students, I used to sweat, even though the profession excited me as well. I believed that I had the capacity to inspire the students in the same manner my former professors inspired me, although I was not well aware of the challenges that lay ahead of me while dealing with the students.\nDuring my undergraduate years, about four years ago, I had come across some professors who did not have the capacity to inspire their students. I often overheard people raising complaints concerning the apathy portrayed by the students, as well as administrators who did not take the time to understand the situation of their students. Some of them complained that they used to work extensively without being accorded the appreciation they deserved. I can remember a time when one professor approached me to warn against joining the institution since he regretted the way he had spent his life without gaining any notable recognition from the school as well as the challenges he faced with the students. He stipulated that the students became lazier after the end of every year. As such, the teaching staff regarded the job of instruction as becoming harder while it was also less rewarding. The conversation I had with the professors led me to think how I would survive in the learning environment on my own.\nOne day, I believed that the professor were an individual who was headed toward retirement and needed to create room for new professionals who had appeared more enthusiastic and motivated to pursue the task, although this was not the case as I later came to realize. I believed I was one of the ideal people for handling the work as based on the trust I had in myself as capable of fostering learning motivation in any environment. I trusted that I had the capacity to influence any student to improve despite any common challenges apparent in the teaching environment. As such, I disregarded the opinions raised by the former professor believing I was capable of transforming the learning atmosphere. Presently, it is three years after I joined the institution where I am teaching. I think that if things go according to the way I want them to, I will be earning tenure soon. I am now wondering whether I was uncharitable to the former professor of the institution, as he might have known certain things that I do not.\nThoughts and Feelings Description\nUpon my discussion with the former teacher of the university I am currently teaching, I was amazed that he felt the job of dealing with the students as challenging. I thought that did not have what it takes to survive in an environment dominated by ambitious students. I felt that he was afraid that the students did not appreciate his efforts in the teaching environment, thus leading him to tire of the dealing with them. In the field of academics, however, I am still relatively fresh with no significant groundwork on how to cope with the diverse terrifying situations associated with the institution. Nevertheless, I feel that I already understand the various exhaustions and frustrations that may lead a college professor to feel as if he had wasted his career while dealing with challenging students. During my initial encounters with my students two years ago, I came across a paper, which a student argued that John Lenin had utilized his Beatles career to serve as a stepping-stone for controlling Russia. I also came across another one that stipulated that in the early 1990s, practices, such as homosexuality and adultery did not exist. Based on the initial encounter with the two papers, I started questioning whether the students had any significant knowledge concerning what they were writing.\nI did not wish to start judging the misconceptions by the students initially as my pedagogue drove me to correct them. Considering myself as an educated person, I used to shake my head as well as laugh whenever I came across such vital misconceptions. At times, however, I would come to the realization that I am the one responsible for marking the papers after devoting more than 14 hours daily during the workdays in educating the students to ensure that they get the concepts right. As such, I would often sit wondering whether this is what I should devote my entire life to depending on the encounters I had with the numerous challenging students. I would even question whether I was capable of making any difference in the lives of the students as they showed no signs of progress even after the numerous efforts I applied to ensure captured the relevant concepts.\nWhenever I was in class with my students, the question repeated itself in my mind every time I heard the cell phones of the students ringing in class or whenever I realized that the essay a student wrote was gathered directly from Wikipedia. At other times, the students that attained a D during the initial submission fail to make any improvements in the following draft. I also wished that the students would talk to me in case they needed any suggestions in writing an influential paper. I realized that every time I repeated the question that prevailed in my mind, it would be possible to apply more profanity based on the frustration I went through with the students. Because of these frustrations, I started realizing that the teaching profession is a daunting one, particularly when one is forced to deal with students with diverse, challenging students. Therefore, I considered reflecting on my past to determine whether my professors felt challenged, or failed to things that might help me cope with the present situation, or if I can learn something new from the students despite their uncooperative behavior in the learning environment.\nReflective Observation\nPresently, I understand self-awareness, self-regulation, and motivation in ways that I did not before serving as an educator in my present environment. I have realized that considering the students as tiring, disrespectful, and annoying is worth reviewing to understand the reasons behind such acts fully. For instance, during my undergraduate years, I used to portray significant respect toward my professors. However, when looking at the students I usually deal with, I often see as if they are mocking the efforts I apply to make them better students. When I look at the encounters I have with my students, I can now look back and understand why the individuals who have been in the profession for most of their lives direct so much frustration toward their students. The situation is usually depressing when one realizes that the experience within the college shows signs of degradation to an extent that it is incomparable to my college years when we used to show significant excitement upon attaining new knowledge.\nI frequently recount an essay from one my former teacher and a good friend, which stipulated that the dream we currently dream concerning the way things used to be is no longer true, while it is more fantastical as it is the case with other types of goals. Indeed, while embarking on my efforts to educate the young adults, I have come to realize that my individual memory has somehow erased my past, mostly because of the detriments I go through for having to face the students who make my life challenging. I even remember when one student in my class considered himself as showing significant respect toward his professors although he usually fell asleep during the introductory English classes in the morning hours. I also recall a time when he handed in a research paper that lacked works cited page since he believed in other things that he considered as better than editing his work before handing it in. In this case, I now realize that students have different perceptions of life and education itself. Therefore, it is the role of the educators to consider reviewing the various situations of the learners to determine the forces behind their unusual behavior to determine the ideal ways of coping with them.\nFurthermore, considering the activities I undertook during my college years if anyone tried telling me that the behavior I exercised portrayed disrespect toward my professors, I would have been dismayed and sad as well. I used to represent profound respect toward my teachers. When reflecting on my sociology professors and others, for instance, I perceived them as the smartest individuals I had ever come across. I believed I have the capacity to ask any question that troubled me and argued that the answer they offered me was the correct one. The obvious intelligence they portrayed made them appear self-assured, confident, and intimidating to a person who only possessed several book collections. Therefore, even though I showed important respect for the obvious intelligence they portrayed as well as values and the profound insights they instilled in me, the admiration I had for them hindered me from asking questions that I believed they were capable of answering. The fear I had for appearing fooling led me to opt for ignorance, which is the same situation I am encountering with the students my students.\nAdded Meaning\nFrom my dealings with the students as well as when focusing on my previous life as a student, I believe I have realized that all people have something to offer irrespective of whether they are students or educators. As an assistant professor as well as an average person, I am quite aware of the ignorance that prevails in me even during the present day. Furthermore, I am mindful of the fact that the professors I used to idealize and idolize must have understood the limitations of their knowledge while they encountered similar doubts that I am still facing to this day. Therefore, one of the things associated with being a learned person revolves around accepting the notion that we do not know everything. As a student, I should have taken the time to overcome my ignorance and ask the right questions to my professors, irrespective of whether I believed they had the answers to them or not. By doing so, I would have managed to identify my weaknesses earlier, thereby prepare me adequately with diverse ways of handling my future career.\nWhen reflecting on my learning and teaching career, I am afraid that if the students of today do not realize the need for identifying the kind of ignorance that characterizes a considerable number of learners, they might assume that the superiority offered by the knowledge we have downgraded them. They might also believe that I am judging them for the ignorance they portray. They might also think that we usually judge them if they direct their ignorance toward us by raising questions they suspect we may be having answers. In this perspective, therefore, it is vital to embark on guiding the students toward identifying the various forms of weaknesses they portray in the learning environment, thereby allow them to be well equipped in matters concerning education and in their interactions with educators.\nI agree,...\nNeed a paper on the same topic?\nWe will write it for you from scratch!\nRequest Removal\nIf you are the original author of this essay and no longer wish to have it published on the SpeedyPaper website, please click below to request its removal:\nStress causes The mission statement Canadian Media Portrayal of Refugees and Immigrants The Renaissance Essay The concept of leadership Global Market Assessment Teaching Vocabulary with Music Racially Theory PROFESSIONAL MEMORANDUM ON CRIMINAL JUSTICE Is Feminism Justified? Healthcare Information Privacy Leadership Experience", "pred_label": "__label__POS", "pred_score_pos": 0.785586416721344}
{"content": "Healthy Hair Wash Powder is chemical-free and has zero preservatives. It only contains natural ingredients, including the goodness of Bhringraj and Tulsi. We harvest Bhringraj, the king of hair Ayurvedic rejuvenators from the Northern plains of India. Our experts ensure that we harvest Bhringraj flowers during optimal periods. Its high nutrient content promotes scalp and hair health. At the same time, the soothing effects of Tulsi boost healthy blood circulation in the scalp.\nWe also added Shikakai. A traditional herb for hair washing and conditioning. We collect its pods when they reach the right maturity stage to retain its astringent and tonifying quality for healthy hair. The inclusion of Brahmi and Amalaki provides cooling properties. Their presence encourages a healthy response against occasional inflammation affecting the scalp.\nWe make the Healthy Hair Wash in a traditional family-owned pharmacy under monitored conditions. Following sustainable Ayurvedic practices, Healthy Hair Wash is formulated according to the classic ancient formulas. Our experts produce Healthy Hair Wash in small batches to optimize effectiveness and preserve its freshness.\nWe collaborate with organic farmers who follow traditional practices to cultivate the ingredient. They follow our guided instructions and do not use any toxic chemicals or pesticides during the harvest and processing.\nWhat's more?\nOur expert practitioners (Ayurvedic Vaidyas classically trained in India) have selected only ethically wildcrafted, and certified organic ingredients for Healthy Hair Wash. Additionally, our organically grown ingredients come from native farms. That way, we ensure that the farmers do not use pesticides or toxic chemicals during the harvest or processing.\nWe also source fresh ingredients, cultivated in the ideal topographical environment. Such careful sourcing increases the quality of the ingredients and the effectiveness of the supplementation.\nWhile we source ingredients in India, we process the product in the USA. That way, we can guarantee that you have access to whole foods and traditional products. Moreover, our herbal supplements go through multiple quality assurance checks before they reach your doorstep. We offer only the best for your health and wellbeing.\nIt's only here that you'll find organic supplementation that helps enrich your body with strength, vitality, and optimal health.", "pred_label": "__label__POS", "pred_score_pos": 0.6030849814414978}
{"content": "Non-Bank Financial Intermediation\nNon-banks play an increasingly important role in the global financial system. It is important therefore that risks from non-bank financial intermediation (NBFI) are effectively managed and that authorities have the tools they need to effectively supervise and regulate NBFI.\nThe FSB has undertaken significant work to assess and address the risks from NBFI since the global financial crisis. A key pillar of the FSB’s work has focused on its annual exercise to monitor NBFI activities and implementing a range of reforms agreed to address problems highlighted by the global financial crisis.\nThe FSB’s regular vulnerabilities work assesses risks across the financial system including risks that may be developing with NBFI. This work is supplemented with deeper dives to better understand emerging risks and agree what coordinated supervisory and regulatory action should be taken.\nDevelopments in credit markets\nThe impact of COVID-19 on credit markets highlighted vulnerabilities in the NBFI sector related to liquidity mismatches, leverage and interconnectedness, and investor behaviour related to certain funds that they may treat as cash equivalents during economic calm but not during crisis. While extraordinary central bank interventions calmed capital markets, which remained open and enabled firms to raise new and longer-term financing, such measures should not be required.\nUnderstanding risk, risk transmission, and policy implications for the NBFI sector is more important than ever. Authorities across the financial sector must develop a shared understanding of our financial system as a whole and build consensus where policy responses may be needed. The FSB has formed a group on non-bank financial intermediation, composed of senior leaders from market regulators, macroprudential authorities, and international organizations, which will build a holistic view of resilience in the NBFI sector. By the G20 Summit this November, the group will carry out a holistic review of the market turmoil that occurred in March by leveraging the various workstreams underway in the FSB and SSBs. In addition, the FSB has begun a mapping exercise of the critical connections between traditional banking and non-bank sectors in a cross-border setting. This combined work will clarify the various points of vulnerabilities and risk amplification and transmission in the financial system, and will inform future steps of the FSB. In 2021 under the Italian G20 Presidency to improve the resiliency of the NBFI sector while preserving its benefits.\nLeveraged loans and collateralised debt obligations\nMarkets for leveraged loans and collateralised loan obligations (CLOs) have grown significantly in recent years, with the majority of issuance concentrated in the US and to a lesser extent the European Union. The securitisation of leveraged loans through CLO issuance, which had come to a halt almost entirely between 2009 and 2010, exceeded pre-crisis levels in 2014 and has remained strong since then. While most leveraged loans are originated and held by banks, and banks have the largest exposure to the market, the role of non-bank financial institutions has increased.\nIn December 2019 the FSB published a report that reached the following conclusions:\nVulnerabilities in the leveraged loan and CLO markets have grown since the global financial crisis. Borrowers’ leverage has increased; changes in loan documentation have weakened creditor protection; and shifts in the composition of creditors of non-banks may have increased the complexity of these markets.\nBanks have the largest direct exposures to leveraged loans and CLOs. These exposures are concentrated among a limited number of large global banks and have a significant cross-border dimension.\nA number of non-bank investors, including investment funds and insurance companies, are also exposed to the leveraged loan and CLO markets.\nGiven data gaps, a comprehensive assessment of the system-wide implications of the exposures of financial institutions to leveraged loans and CLOs is challenging.\nThe FSB will is considering what steps can be taken to close data gaps and continues to analyse the financial stability risks. It has also continued to assess the regulatory and supervisory implications associated with leveraged loans and CLOs.", "pred_label": "__label__POS", "pred_score_pos": 0.5751903057098389}
{"content": "PRESENTATION\nContact: Jacqueline Sánchez\nThe recent announcement by BP CEO\nBernard Looney for the company to attain net zero emissions by 2050 is the latest news to ripple across the global oil industry with a direct link to confronting the climate challenge. Development of international agreements targeting emissions reduction, national policies and corporate goals are all placing increasing focus on the role of oil in a post-2050 world. This is particularly true for the large-scale, highly complex and capital-intensive projects in the sector that often take a decade or more to bring online. Layered on top of the foregoing is polarizing climate change activism and demands on oil and gas companies and the sector writ large. This begs the question of whether we are reaching the moment when it may already be too late for major new offshore oil development?\nJoin us for a webinar with\nJed Bailey, Managing Director of Energy Narrative and long-time Latin American energy analyst. Bailey will share his insights on the intersection of climate activism and the oil and gas sector with insights for the region, particularly the possible implications for deepwater projects in Brazil and Mexico and the nascent oil sector in Guyana and Suriname. The webinar will be held Tuesday, March 10 at 10:00am San Diego (12:00 pm Houston; 1:00 pm New York; GMT/UTC – 8 hours). The webinar will include a live Q&A session with the audience.", "pred_label": "__label__POS", "pred_score_pos": 0.9050436019897461}
{"content": "Management models - love them or hate them, they're at the heart of management thinking and practice. They have two main purposes: to provide a framework for improving business performance; and to confuse the uninitiated with buzzwords and acronyms.\nYou've heard of balanced scorecards, CRM, just-in-time and SWOT? How about the Deming cycle, parenting advantage or socio-technical organizations? Even if you have, can you describe them clearly and do you know how you can use them in your business?\nKey Management Models takes the reader through each of the essential management tools in a clear, structured and practical way. It provides comprehensive coverage of the main tools, and of the models developed by the Gods of management thinking: Belbin, Handy, Kotter and Mintzberg.\n1. Activity based costing\n2. Adizes' paei management roles 3. Ansoff's product/market grid 4. Balanced scorecard 5. The BCG matrix 6. Belbin's team roles 7. Benchmarking 8. Business process redesign 9. Capability maturity model 10. Change quadrants 11. Chaos model 12. Competitive analysis: Porter's five forces 13. Compliance typology 14. Competing values of organizational effectiveness 15. Core competencies 16. Covey's seven habits of highly effective people 17. Customer marketing and relationship management 18. The Demming cycle 19. The EFQM model 20. Eisenhower's effective time management 21. Four competencies of the learning organization 22. Generic competitive strategies 23. Greiner's growth model 24. Handy's Gods of management 25. Hofstede's Cultural Dimensions 26. Just-in-time 27. Kaizen 28. Kay's distinctive capabilities 29. Krajlic's purchasing model 30. Kotter's eight phases of change 31. MABA analysis 32. Malcolm Baldridge award 33. 7-S Framework 34. Mintzberg's Configurations 35. Nolan's IT growth stages 36. Offman's core quadrants 37. Overhead value analysis 38. Parenting advantage 39. Production models 40. Risk award analysis 41. Schools of strategy synthesis 42. Seven forces model 43. Simon's levels of control 44. Sociological organization 45. SWOT analysis 46. The fifth discipline 47. The neurotic organization 48. Value chain 49. Value disciplines", "pred_label": "__label__POS", "pred_score_pos": 0.5343410968780518}
{"content": "An Introduction to Civic Practice Civic practice draws on opera’s authentic creative assets to address public priorities and community needs.\nThe leaders who undertake this work have a deep respect and nuanced understanding of a community’s historical context and existing cultural norms, are strong partners with organizations from different sectors, and focus on stewarding a process of relationship-building and co-creation.\nAn Introduction to Civic Practice, published by OPERA America, shares learning from the 2016 and 2018 meetings of the Civic Action Group, a peer-learning cohort of company representatives working to explore how opera can increase its capacity to address civic priorities. The Civic Action Group was supported by an Our Town grant from the National Endowment for the Arts.", "pred_label": "__label__POS", "pred_score_pos": 0.836048424243927}
{"content": "Smart City Mobility Smart cities, mobility, and the road in between Smart City Bike Services: Economic, Environmental and Societal Impacts\nThe number of bike-sharing programs globally doubled between 2014 and 2018, while the number of bikes increased twenty-fold. Today, there are over 17 million shared bikes in use, about 10 million of them in China. Demand is rising in Europe and the US too.\nWhile cycling has increased in popularity over the last decade, there has been a recent shift in favor of e-bikes and e-scooters, which are easier to use and don’t require pedaling. Research shows that in cities where both options were available, e-scooters were five times more popular than pedal bikes. 40 million e-bikes are expected to be sold worldwide in 2023.\nCycling, micro-transport, and bike-sharing trends go hand in hand with the rise of smart city technologies. Cities desperately need an alternative to private car ownership, and bicycles and light electric vehicles are increasingly perceived as a solution. Smart cities are encouraging light modes of transport and building infrastructure and policies to support them, in the hope that they can reduce the burden on road infrastructure, and improve quality of life in city centers.\nIn this article you'll learn about: What is Bike-Sharing?\nA bike sharing system is a service that allows members of the public to use bicycles for short periods of time. Some services are free, some are paid, and most provide apps that map out a network of bikes located throughout the city. Some bike sharing companies reimburse the city for the space that their bikes occupy. Bike sharing systems can use docking stations, or they can be dockless.\nDocked bike share services use computerized bike racks that lock the bikes, releasing them only when a user enters payment information. Docked services are well-suited for daily commutes, as the stations are typically located in strategic positions. A potential drawback is that users might find an empty station, or face problems docking the bike at the end of their trip if the station is full. Dockless bike share services are a newer development and are especially suitable for single, short trips. Riders use a smartphone app to locate bikes, which they can unlock with their phones. Users can then park the bikes anywhere within a designated area, locking them on ordinary bike racks or fences.\nDockless bikes are usually cheaper and more convenient than docked bikes because you can park them right at your destination. However, misplaced bikes can be an issue, as it is harder for authorities to prevent parking on the road. One way to regulate this is to offer incentives like credit points to users who return the bikes to designated areas.\nBike-Sharing Benefits\nBike-sharing services can have a dramatic impact on cities in which they operate, benefiting both the local economy and the environment.\nEconomic Benefits\nBike-sharing offers economic benefits for individuals and cities alike. For individuals, bike-sharing services offer a cost-effective alternative to private cars and taxis. For cities, the low-cost nature of bike-sharing allows users to spend more money at local businesses. Several studies have confirmed that people who travel by bike tend to spend more than those who drive.\nAnother economic benefit is the data accumulated by bike-sharing services, which provides information on commuter patterns. This information offers cities and service providers the opportunity to earn revenue via advertising and can help cities plan their services and policies.\nEnvironmental Benefits\nBike-sharing schemes reduce fuel consumption, emissions, and congestion in city centers. Bike-sharing also encourages physical activity and can contribute to the health of city residents. The US government recommends a weekly minimum of 150 minutes of moderately intense physical activity, and cycling to work is an easy way to achieve this goal.\nBike-Sharing Downsides and Best Practices\nBike-sharing can also have a negative impact on cities. Mismanaged bike-sharing systems can cause issues: if there are too many bikes relative to demand, or if bike-sharing companies fail to collect damaged bikes, they can take up public space and inhibit movement.\nIf you are implementing or considering a bike sharing program, consider these best practices:\nProvide a regulatory frameworkand collaborate with bike-sharing companies to establish successful bike sharing systems. Build infrastructurethat favors cyclists and integrates bike-sharing systems with other modes of transportation, like trains. Initially limit the number of bikes, allowing for growth to match demand. Provide enough bike racks to protect public space. Shift responsibility to bike-share companies, requiring them to maintain their infrastructure and remove dysfunctional bikes immediately. Examples of Leading Bike-Sharing Services\nIt might be useful to familiarize yourself with leading bike service providers, understand their mode of operation, policies, and pricing, as you consider a bike service program. The following are bike sharing services with a global presence:\nMobike: Operates over five million bikes, with 100 million users taking up to 25 million trips per day. The company encourages riders to park at Mobike Preferred Locations and provides incentives for good parking practices. Users can also receive Mobike Credits for reporting illegally or badly parked bikes. It is based in Beijing and is valued at around $3 billion. Lime Bikes: Offers electric bicycles and scooters as well as traditional bikes. Users locate the GPS-fitted dockless bikes through a mobile app. Lime charges $1 for a 30-minute trip and is especially popular on college campuses. The company is valued at $2 billion and has its headquarters are in San Francisco. The Broader Impact of Smart City Bicycle Programs\nA new study from the University of Kentucky showed that shared bicycle and scooter services may be reducing the usage of buses; every 1,000 bikes on or near a bus route contributed to a decrease of over 1.7% in bus rides. The same study showed bike sharing may be encouraging consumers to take trains. However, other research shows few shared bike users switch over from private cars.\nTogether with the impact on local economies, pollution, congestion, and personal health, bike-sharing services are much more than a curiosity and are becoming a central part of smart city strategies. Smart city bike programs are inexpensive to manage and can make a major contribution to smart city goals. Even if they do not, as of yet, reduce private car ownership, they contribute to a compelling ecosystem of public transport options that are creating a new mobility economy.", "pred_label": "__label__POS", "pred_score_pos": 0.5404196977615356}
{"content": "Creating SciComm Workshop at CSPC 2019 ABOUT THE PANEL //\nWith growing divides in public and scientific opinion on controversial science policy issues like data privacy, vaccinations, and climate change, there has never been a more pressing time to improve how we communicate science.\nIn a step toward achieving this goal, Art the Science team members Alice Fleerackers (ScholCommLab), Julia Krolik (Pixels and Plans), Cat Lau (CHILD-BRIGHT Network), and Dorina Simeonov (AGE-WELL NCE Inc.) shared their science communication expertise at this year’s Canadian Science Policy Conference in a panel titled Creating SciComm: An interactive session connecting scientists, policymakers, and the public. Collaborative and participatory, the panel offered a hands-on approach to communicating science through visual methods. Attendees used paper, markers, glue sticks, and their own creativity to engage with four themes of public concern: climate change, artificial intelligence, genetically modified foods, and vaccinations.\nDuring the session, participants learned to embrace their creativity, work together, and harness the power of visual communication to make science more understandable, accessible, and engaging. In less than an hour, they produced these 55 unique infographics—evidence of their originality, enthusiasm, and willingness to connect with communities beyond the conference.\nPARTICIPANT INFOGRAPHICS // VIDEO INTERVIEWS // SESSION GALLERY //", "pred_label": "__label__POS", "pred_score_pos": 0.9397478103637695}
{"content": "When we consider making changes in our lives, we often look at the reasons why not to change first, then look at the reason why we should change.\nThis resistance is both genetic and biological. It takes a lot to go against this programming, but when we do, when we make the effort to truly think and act differently, the rewards are tremendous!", "pred_label": "__label__POS", "pred_score_pos": 0.9480372667312622}
{"content": "These online and certified (by University of College of Estate Management – UCEM) learning modules will provide ex-military with knowledge that will enable them to take the first step towards becoming\nsite and employment ready, i.e. gain an understanding of the construction industry as defined by employers. For example: how a construction project and a construction site operate, roles and career pathways, specific knowledge/understanding required by employers, overcoming barriers faced by ex-military.\nThese bespoke modules are developed through qualitative and quantitative research using surveys, along with veteran and employer focus groups. This research identified the particular issues/challenges faced by ex-military and employers and created content designed to resolve these issues.\nThe outcomes of these transferable\npre-employment learning modules are:\nUpon completion of the modules, certification will be gained from UCEM and this accreditation can be used as evidence to employers of the individual’s knowledge of and commitment to a particular profession.\nThis UCEM accreditation will also come with a commitment from UCEM that the individual is\nguaranteed a place on a relevant UCEM course for onward learning. This offer can be taken up as the individual moves into employment.", "pred_label": "__label__POS", "pred_score_pos": 0.6877179741859436}
{"content": "The Internal Revenue Service (IRS) has recently issued the Transfer Pricing Examination Process (TPEP) (Publication 5300(6-2018)), replacing the Transfer Pricing Audit Roadmap issued in 2014. As every transfer pricing issue is unique, transfer pricing examinations are factually intensive and require a thorough analysis of functions, assets, and risks, along with an accurate understanding of relevant financial information The TPEP provides a framework and a guide to best practices and processes to assist with the planning, execution, and resolution of transfer pricing examinations. The TPEP will be shared with taxpayers at the start of a transfer pricing examination, to help them understand the process and work effectively with the examination team – it will be updated regularly based on feedback from examiners, taxpayers, practitioners, and others.\nThree phasesThe TPEP is comprised of three sections: Planning Phase, Execution Phase, and Resolution Phase. During the planning phase, the scope of the audit will be determined and the examination team will work with the taxpayer to establish a plan to complete the examination in a timely manner. The examination plan will be issue-focused and contain the issues identified, audit steps, timelines, and communication agreements. During this phase, the IRS issue team will gather, review, and analyze data and compute key financial ratios in order to develop a preliminary working hypothesis. This phase concludes with the opening conference.\nDuring the execution phase, the issue team will conduct interactive discussions with the taxpayer, including using the Information Document Request (IDR) process, to develop the facts. Prior to the taxpayer orientation meetings, the issue team will review and analyze the taxpayer’s transfer pricing documentation and note areas requiring further development, confirmation, or inquiry. The issue team will also review and analyze relevant intercompany agreements and conduct functional analysis interviews, plant tours, and site visits. The taxpayer must provide the documentation within 30 days of an IRS request. Once the issue team has finished the execution phase, it will meet with the taxpayer to discuss all issues before finalizing the Notice of Proposed Adjustment (NOPA) and the Economist Report.\nThe goal of the resolution phase is to reach an agreement, if possible, on the tax treatment of each issue examined. If a field resolution is not reached, then the normal administrative procedures will ensue. PenaltiesThe TPEP states that penalties should be considered whenever adjustments are made to a tax return. This is in line with a separately issued IRS directive (January 2018) instructing Large Business & International examiners to more aggressively assert penalties in certain transfer pricing examinations. The issue team is directed to discuss the imposition of penalties at the same time as the primary adjustment.", "pred_label": "__label__POS", "pred_score_pos": 0.5259084701538086}
{"content": "____________________ 2009 Auto Restructuring Rising Used Car Prices Point to Recovery in the New Auto Market, According to Scotia Economics\nTORONTO - Used car prices, a key leading indicator of the health of the overall auto market, are strengthening and point to a continuation in the global auto sales recovery, according to the latest Global Auto Report released by Scotia Economics.\n\"Historically, cyclical turning points in pre-owned vehicle prices lead directional changes in the new car and light truck market by three to six months, reinforcing our view that the outlook for new vehicle sales has improved significantly and that a sustained cyclical recovery is underway,\" said Carlos Gomes, Senior Economist and Auto Industry Specialist, Scotiabank. \"Interestingly, over the past two years, the cyclical turning points in U.S. used car prices have led not only the new vehicle market, but also the directional changes in the overall economy.\"\nAuto Sector Credit Trends\nAccording to the report, the increased prominence of used vehicle prices as a leading indicator of overall economic activity reflects changes in credit availability. Aside from improved access to credit, a pickup in household confidence was also a key factor stimulating used vehicle demand. Consumer confidence in the United States bottomed at a record low in February (data back to 1970), before bouncing back over the summer.\nReduced Supply Will Support Prices Going Forward\nA reduced supply of used vehicles, due to a sharp decline in new fleet purchases, as well as the drop in leasing over the past year, are structural changes that will continue to support used vehicle prices in both the United States and Canada. This suggests that, in both countries, firmer used car prices will be a multi-year phenomenon, not just a short-term cyclical development.\n\"In Canada, new fleet purchases will likely drop to less than 180,000 units in 2009, 100,000 units fewer than the average of the past decade and less than half the record volumes of the late 1980s,\" said Mr. Gomes. \"In addition, the number of new leased vehicles in Canada will slump below 400,000 units this year, the lowest level since 1995. These sharp reductions will lead to a decline in the number of vehicles supplied to the Canadian used vehicle market by 2011.\"\nGlobal Auto Recovery Remains Intact\nIn September global car sales, excluding the United States, posted a double-digit year-over-year increase - the strongest gain since April 2008.\nKeeping with the global trend, Canadian new car and light truck sales also remained strong in September. Purchases exceeded an annualized 1.50 million units for the third consecutive month - the best performance since last October, before the late-2008 sharp sales downturn.\n\"This suggests that Canadian households are becoming more confident as economic conditions stabilize,\" commented Mr. Gomes. \"We estimate that this trend remains intact, with volumes surpassing an annual rate of 1.50 million units in October.\"\nIn contrast, new vehicle purchases in the United States fell to an annualized 9.2 million units in September, as demand softened from the 'cash for clunkers'-induced 12.7 million units of the previous two months. However, volumes remained roughly in line with the level prevailing in June, prior to the introduction of the government subsidy. Purchases also remained above the early-2009 cyclical low of 9.0 million units. This suggests that the impact of the 'sales pull ahead' from the government program has largely run its course.\n\"In fact, Scotia Economics believes that low inventories also had a significant impact on dampening sales in the United States last month,\" concluded Mr. Gomes. \"Preliminary estimates suggest that overall industry volumes are bouncing back, with purchases back above an annualized 10 million units in October.\"\nScotia Economics provides clients with in-depth research into the factors shaping the outlook for Canada and the global economy, including macroeconomic developments, currency and capital market trends, commodity and industry performance, as well as monetary, fiscal and public policy issues.", "pred_label": "__label__POS", "pred_score_pos": 0.6097052097320557}
{"content": "This guide from the Commonwealth Secretariat is not intended as a blueprint for implementing gender-responsive budgeting. Instead, it was developed to present basic information about gender budgets so that those\nThis resource pack provides relevant knowledge to facilitate mainstreaming gender-responsive approaches into reproductive health programs, and the inclusion of specific aspects of gender inequality and disadvantage into national policy frameworks.\nThis report discusses the compliance of government budgets with the Convention on the Elimination of All Forms of Discrimination Against Women (CEDAW). It covers expenditure, revenue, macroeconomics of the budget,\nThis paper proposes gender-responsive budgeting as an effective tool for monitoring the accountability of fiscal policy. Bakker first analyzes the relationship between budget and accountability in general, focusing on comprehensiveness,\nThis publication is divided in four sections to provide a comprehensive understanding of gender-responsive budgets. It describes the evolution of work in this area, assesses the role of different stakeholders,", "pred_label": "__label__POS", "pred_score_pos": 0.9253205060958862}
{"content": "Prioritise education in conflict-affected areas: Across the world 28 million1 primary school-age children living in conflict-affected countries are out-of-school, and they form half of the world’s total out-of-school population. During conflict, infrastructure assets such as schools are damaged or completely destroyed during fighting. Children may choose to stay away from school due to their and their family’s safety fears in the midst of conflict, or the need to supplement their family’s income amidst conflict-related financial loss. Children who are internally displaced by conflict face a particularly challenging task accessing education due to the specific conditions created by their displacement, such as loss of livelihoods making school fees hard to find, and discrimination from host communities. Children caught in conflict are being deprived of their right to education2 and denied the opportunity to benefit from the protective and life-sustaining mechanisms of education.\nDRD, children, protection, education, Internally Displaced Persons,", "pred_label": "__label__POS", "pred_score_pos": 0.9453738927841187}
{"content": "This course will prepare you for the CSSLP® exam. It examines the first domain in the field of Secure Software - understanding the core security concepts that must be designed and built into all software regardless of language or implementation.\nMany applications written today are vulnerable to attack or compromise. This is because many developers are unaware of how to incorporate security principles into their applications. In this course, CSSLP®: Secure Software Concepts, you'll learn the foundational concepts of security in relation to application development, and be provided with the basis for building secure software that will withstand the attacks it will face - both accidental and intentional adverse events. First, you'll explore core concepts of secure software. Next, you'll dive into understanding the process of security design. Finally, you'll cover how to understand risk in a controlled environment as it applies to software. By the end of this course, you'll have a solid understanding of the core secure software concepts and be prepared to progress into the next domain.\nKevin Henry is a passionate mentor and educator in the fields of information security and audit. Mixing experience with knowledge, Kevin delivers effective training programs for companies and individuals worldwide. A frequent speaker at prestigious conferences, Kevin is known for a clear understandable manner of imparting practical information and explaining difficult topics.\nCourse Overview Hi everyone. My name is Kevin Henry, a security consultant and computer analyst programmer and a holder of the CSSLP, the Certified Secure Software Lifecycle Professional certification. Welcome to my course on Secure Software Concepts, the first domain of the CSSLP certification. This course will help you prepare for and develop, implement, operate, and maintain secure software programs, and assist you in preparing for the CSSLP examination. This course is based on the latest version of the exam outline used to create the examination questions. I work in outreach as a security evangelist at Team Cymru, and I've been involved in the field of information systems, programming, security, and audit for many years. And I look forward to sharing with you knowledge and experience that can help you understand the techniques and objectives used to design secure programs. Software applications have become a favorite playground and point of compromise for criminals and hackers. Therefore, writing secure programs is essential. This course will examine the steps in secure software development, and address the ways to integrate security into the systems and software development lifecycle processes. Some of the major topics we will cover include the core concepts of secure software, the process of security design, and understanding risk in the control environment as it applies to software. By the end of this course, you'll have a solid understanding of the core secure software concepts, and be prepared to progress into the next domain of secure software requirements. I hope you'll join me on this journey to learn about the value, benefits, and features of the secure software lifecycle, and the role you can play in this exciting and rewarding field through this course at Pluralsight.", "pred_label": "__label__POS", "pred_score_pos": 0.8603150248527527}
{"content": "In the 1970s the cultural historian William Irwin Thompson described Richard Nixon’s resignation as U.S. President as the end of the presidency itself. He believed that Nixon’s departure symbolized a shift in the power of the office rather than just the failure of one man. The idea that leadership in the Oval Office may not be significant corresponds with the transit of transformational Pluto through executive Capricorn from 2009-2023, especially now with revolutionary Uranus coming into a stressful 90-degree square with Pluto. The point is that institutions are changing, including that of the Chief Executive in the United States, regardless of who she or he may be.\nThompson’s idea came to mind recently when I looked at the natal charts of Newt Gingrich and Mitt Romney, the leading candidates for the Republican nomination. Gingrich, unsurprisingly, is a glib Gemini with the Moon in philosophical Sagittarius with both making stressful squares to dreamy Neptune. He also has verbal Mercury in chatty Gemini closely conjunct unconventional Uranus. None of these were surprising but what is remarkable is the lack of planets in the early degrees of season starting Cardinal signs, where Uranus and Pluto will continue to trigger changes through 2015.\nMitt Romney is a Pisces with the Moon in Scorpio with only diaphanous Neptune at 9 Libra in the Uranus-Pluto transit zone. This lack of planets at these critical points made me think that neither man would be a meaningful change agent during the next few years. Barack Obama fares slightly better with sociable Venus at 1 degree of Cancer, but that’s still relatively trivial with respect to where the major planetary action is. (Transformational Pluto’s opposition to Obama’s Venus at the time of his inauguration in January 2009 reflects the breakthrough as the first mixed race U.S. president.) The absence of astrological activity is not proof of cultural insignificance but it does suggest that none of these men are likely to lead us into the dawn of a new age, which corresponds with William Irwin Thompson’s decades old belief in the withering power of the American presidency.\nIt isn’t surprising, though, that an office that requires vast amounts of money and media attention to obtain is not going to represent the cutting edge of American consciousness. The seven-year transit of Uranus in independent Aries is, as I’ve often stated, about individual breakthroughs leading the way to collective change. The leadership we seek lies within each of us. Yet surprisingly, Vladimir Putin’s Sun at 13 Libra is in the Uranus-Pluto transit zone, suggesting that he may play a greater role in shaping the future than the three Americans mentioned. This doesn’t mean that the old KGB spymaster will be transformed into an angel of enlightenment but that changes in Russia may be have more impact on the world’s future than we expect.", "pred_label": "__label__POS", "pred_score_pos": 0.5825897455215454}
{"content": "I. Citizenships in Europe: harmony and conflict. – I.1. A curious legal status perched on limitations. – I.2. EU citizenship: two lessons. – II. EU citizenship: questioning the established narrative. – II.1. Empowering the citizen – Humiliating the State. – II.2. Promoting democracy – Undermining democratic outcomes. – II.3. Promoting non-discrimination – Undermining equality. – II.4. Implications for the rule of law: the sole possibility of one type of constitutionalism. – III. We have time: the new picture is here to stay. Table of Contents: European citizenship, although derived from the nationalities of the Member States, came to play a significant independent role in reforming European constitutionalism in unanticipated ways by undermining some of the key assumptions underlying the notions of citizenship, equality and democratic accountability. Instead of lingering merely as a super-structure atop Member State nationalities, it instead reshuffles the constitutional basics and not all Europeans emerge as winners as a result. This brief Abstract: Articleprovides an introductory background for the Special Section on EU citizenship and rights of European Papers, Vol. 3, 2018, No. 3 and outlines some of the core tensions which EU citizenship brings to light. EU citizenship – equality – justice – conferral – wholly internal situations – Member State nationalities. Keywords:\n* Professor of EU Constitutional Law, University of Groningen, d.kochenov@rug.nl.", "pred_label": "__label__POS", "pred_score_pos": 0.5463564395904541}
{"content": "Qualifying for a rental home can be as challenging as a home purchase. However, there are ways around finding the right property for you!\nFirst, engaging a real estate professional like myself is key. You've heard the old adage: \"It is not always what you know but who you know.\" It is about the relationship between the two agents and the relationship between the Landlord and their agent.\nIn the event you have marginal credit or what could be considered a derogitory background check: Here are just a few things that may allow you to rent with those issues:\nFind an individual landlord vs a Management Company Pay a larger deposit or rent in advance Use letters of recommendations Find someone to co-sign for you Find a roommate Pay extra per month\nRecommendations are weighty. Especially when they come from credible sources, such as a current or previous landlord, employer, even a roommate. These letters of recommendation shouldn’t only be glowing tributes to your character. They should also give insight into the nature of your financial relationship with the writer of the letter. This would soften the impact of negative entries on your credit report.\nYou may source for endorsements from landlords who you only had short-term leases with or even get a reference letter from your bank. The bottom line is that letters of recommendation should put your landlord at ease about responsibility and financial capability.\nAs your representative, these are a few of the things that I can negotiate on your behalf. I will work tirelessly representing you and only you! As compared to the Listing Agent who works for the Landlord and is obligated contractually to work only in their best interest.\nRemember Real Estate Experience is not Expensive - It is Priceless... It will save you time and money! I look forward to serving your real estate rental needs! Call or Text for a direct prompt response: 281-703-0016", "pred_label": "__label__POS", "pred_score_pos": 0.6162052154541016}
{"content": "Bibtek download is not availble in the pre-proceeding\nFeng Xie, Ruichu Cai, Biwei Huang, Clark Glymour, Zhifeng Hao, Kun Zhang\nCausal discovery aims to recover causal structures or models underlying the observed data. Despite its success in certain domains, most existing methods focus on causal relations between observed variables, while in many scenarios the observed ones may not be the underlying causal variables (e.g., image pixels), but are generated by latent causal variables or confounders that are causally related. To this end, in this paper, we consider Linear, Non-Gaussian Latent variable Models (LiNGLaMs), in which latent confounders are also causally related, and propose a Generalized Independent Noise (GIN) condition to estimate such latent variable graphs. Specifically, for two observed random vectors $\\mathbf{Y}$ and $\\mathbf{Z}$, GIN holds if and only if $\\omega^{\\intercal}\\mathbf{Y}$ and $\\mathbf{Z}$ are statistically independent, where $\\omega$ is a parameter vector characterized from the cross-covariance between $\\mathbf{Y}$ and $\\mathbf{Z}$. From the graphical view, roughly speaking, GIN implies that causally earlier latent common causes of variables in $\\mathbf{Y}$ d-separate $\\mathbf{Y}$ from $\\mathbf{Z}$. Interestingly, we find that the independent noise condition, i.e., if there is no confounder, causes are independent from the error of regressing the effect on the causes, can be seen as a special case of GIN. Moreover, we show that GIN helps locate latent variables and identify their causal structure, including causal directions. We further develop a recursive learning algorithm to achieve these goals. Experimental results on synthetic and real-world data demonstrate the effectiveness of our method.", "pred_label": "__label__POS", "pred_score_pos": 0.9270035028457642}
{"content": "Bibtek download is not availble in the pre-proceeding\nChristian Naesseth, Fredrik Lindsten, David Blei\n<p>Modern variational inference (VI) uses stochastic gradients to avoid intractable expectations, enabling large-scale probabilistic inference in complex models. VI posits a family of approximating distributions q and then finds the member of that family that is closest to the exact posterior p. Traditionally, VI algorithms minimize the “exclusive Kullback-Leibler (KL)” KL(q||p), often for computational convenience. Recent research, however, has also focused on the “inclusive KL” KL(p||q), which has good statistical properties that makes it more appropriate for certain inference problems. This paper develops a simple algorithm for reliably minimizing the inclusive KL using stochastic gradients with vanishing bias. This method, which we call Markovian score climbing (MSC), converges to a local optimum of the inclusive KL. It does not suffer from the systematic errors inherent in existing methods, such as Reweighted Wake-Sleep and Neural Adaptive Sequential Monte Carlo, which lead to bias in their final estimates. We illustrate convergence on a toy model and demonstrate the utility of MSC on Bayesian probit regression for classification as well as a stochastic volatility model for financial data.</p>", "pred_label": "__label__POS", "pred_score_pos": 0.8885694146156311}
{"content": "Diabetic retinopathy (DR) is the most prevalent microvascular complication of diabetes and a leading cause of preventable blindness in the working-age population. However, due to a lack of suitable biomarkers, its prediction in asymptomatic patients is insufficient. Currently, DR is diagnosed at a stage when typical morphologic lesions become fundoscopically visible. Yet, chronically elevated blood glucose levels lead to characteristic alterations in retinal vessel caliber, blood flow, oxygen saturation, and the capillary network, which precede DR lesions. Furthermore, emerging evidence suggests that retinal neurodegenerative changes occur early in diabetes, initiating a disintegration of the retinal neurovascular unit prior to the appearance of microvasculopathy in DR. This chapter will discuss recent research achievements toward understanding the complexities of DR pathophysiology. It will focus on the nomination of potential imaging biomarkers for the prediction of DR development and progression using innovative structural, functional, and metabolic imaging techniques, including optical coherence tomography angiography (OCTA), retinal oximetry, ultra-wide field FA, and corneal confocal microscopy (CCM). Validation of these biomarkers would allow the identification of patients at high risk of developing DR and might initiate a swift move to early diagnosis and individualized care.\nPart of the book: Early Events in Diabetic Retinopathy and Intervention Strategies", "pred_label": "__label__POS", "pred_score_pos": 0.9917518496513367}
{"content": "A transportation investment that materially improves links between centres opens up previously unavailable options for new activities. Traditional cost-benefit analysis does not adequately take account of the value of this option; real options theory must be added to the analysis to evaluate the full benefits.\nThis paper uses a specific example, Auckland's Harbour Bridge, to motivate the importance of real options analysis. Using illustrative, multi-period models of the real options problem, it highlights how inclusion of real options factors may either increase or decrease the attractiveness of a proposed investment.\nThe models identify situations in which it is optimal to invest even where a standard benefit-cost ratio is less than one.", "pred_label": "__label__POS", "pred_score_pos": 0.5358800888061523}
{"content": "Finding HIPAA Compliant IT Services (Tips & Insights)\nFinding a HIPAA compliant company offering IT services in Rhode Island can be a challenge.\nAs a small or mid-sized medical organization, you need to choose a HIPAA compliant IT company that will secure protected health information (PHI) and comply with HIPAA requirements, while at the same time protecting people’s data, optimize operations, and reduce costs.\nDiscover what a HIPAA compliant IT service looks like and how to find one.\nWhat Is HIPAA?\nHIPAA stands for Health Insurance Portability and Accountability Act. It sets standards for protecting sensitive patient data. Medical organizations with PHI need to have security protocols for their system, equipment, and processes. They should follow these measures to ensure HIPAA compliance. Any partner, contractor, or sub-contractor that the medical organization works with and has access to the PHI needs to be HIPAA compliant.\nProtected health information (PHI) refers to any data held by a covered entity concerning health care, health status, or payment for health services that one can link to an individual. It covers 18 fields of electronic PHI (e-PHI), such as Name, Social Security Number, and Diagnosis. HIPAA requires the organization to disclose this information to a person within 30 days upon request.\nWhat Are HIPAA Privacy and Security Standards?\nThe Department of Health and Human Services (HHS) outlines that HIPAA Privacy Rules establish national standards for protecting PHI. The Security Rule defines national security standards for protecting PHI transferred or held in electronic form.\nHIPAA Security Rules operationalize HIPAA Privacy Rules by addressing the safeguards that covered organizations need to secure e-PHI. HHS’s Office of Civil Rights (OCR) enforces the Privacy and Security Rules. Medical organizations that violate the rules directly or by association get penalties, such as fines.\nWhy Do Companies Offering IT Services Need to Comply to HIPAA Standards?\nAs medical organizations embrace technology, HIPAA compliance becomes critical to secure e-PHI. Cybercriminals may target the data, which makes the rules necessary to protect them. With the rules in place, an organization can adopt innovations while protecting the details of patients.\nHIPAA Security Rule is flexible enough to allow the relevant institutions to implement procedures, technologies, and policies that suit their size, structure, and risks to e-PHI. The company providing your organization with IT services in Rhode Island needs to comply with HIPAA Regulations and Rules. This requirement protects your PHI and saves you from penalties for violating them.\nOverview of HIPAA Rules and Regulations\nHIPAA Regulations and Rules specifications and standards include:\n1. Administrative Safeguards\nAdministrative safeguards are procedures and policies that show how the medical institution will comply with the act. They include:\nCovered institutions need written privacy procedures and policies. They should designate a privacy officer to develop and implement all required procedures and policies. The written privacy procedures and policies need to reference management supervision and institutional agreement to observe the set security controls. The procedures should restrict access to e-PHI to personnel that need them for their functions. It should list the allowed workers or classes of employees. The policies need to address access authorization, modification, establishment, and termination. The policies need to outline how ongoing training for the relevant staff handling the e-PHI will happen. The policies should ensure external partners, such as contractors and sub-contractors, are HIPAA compliant. A medical organization can achieve this compliance by including clauses in the contract requiring the external organization, such as an MSP, to comply with HIPAA Rules and Regulations. The policies should outline a contingency plan for emergencies, such as backups and change control procedures. The policies should specify the frequency, scope, and procedures of audits. Audits need to be both event-based and routine. The regulations need to specify the instructions for responding and addressing security breaches under HIPAA rules. 2. Physical Safeguards\nPhysical Safeguards are measures that control physical access to prohibit inappropriate access to e-PHI. They include:\nPhysical Safeguards include protocols that govern the removal or introduction of software and hardware. Equipment removed from service need to undergo disposal procedures to safeguard e-PHI. Measures that control and monitor access to hardware or software with e-PHI. Only allowed personnel should access them. They also include protocols that control access powers, such as maintenance records, facility security plans, and visitor logbooks and escorts. They include measures that govern the use of workstations, such as their strategic locations away from unrestricted areas. Protocols for ensuring external partners know and comply with physical access rules and regulations. 3. Technical Safeguards\nTechnical Safeguards control access to computer networks and enable the relevant organizations to secure communications involving e-PHI done in open networks to ensure they reach the recipient. They include:\nInformation systems with PHI need protection from intrusion, such as adequate encryption for open or closed networks. Data integrity is essential, including the double-keying, digital signature, use of a checksum, and message authentication to ensure data integrity. External entities that the covered entity communicates with also need some authentication, such as password systems, telephone callback, token systems, and three-way handshakes. Covered organizations need to document their HIPAA compliance and avail supporting documents to the relevant government agencies to determine compliance. IT documents should include written policies, procedures, access records, and all configuration settings for components of networks. Covered entities need documented risk management and analysis programs. Why Choose TAG As Your HIPAA Compliant IT Services Provider\nTechnology Advisory Group (TAG) provides IT support and IT services to organizations in Rhode Island, such as managed IT services, cybersecurity solutions, cloud technologies, and IT consulting.\nWhen you choose us as your IT services company we bring:\nIT support from an MSP that meets HIPAA requirements for a secure network, including workstations, wireless connections, and mobile computing 24/7/365 support Reliable cybersecurity to protect your IT infrastructure A team of experienced professionals Visible returns for your IT expenditure and we will help you understand how you are enjoying our services Customized support to help your organization benefit Advice on how you can better use IT support or innovations to help you achieve your objectives\nConsult with us today and let us help you leverage HIPAA compliant IT services to achieve your goals.", "pred_label": "__label__POS", "pred_score_pos": 0.5352866649627686}
{"content": "We're familiar with the concept of packing a \"Go Bag\" in the 3rd trimester of pregnancy, or if serving as active duty military. If you're someone with chronic illness who may need an emergency trip to the hospital, or someone who is at increased risk of hospitalization during the COVID 19 Pandemic, it's a good idea to pack a \"Go Bag\" now.\nIn the preceding blogs titled Crash Course in Nursing Homes, Part 1, Part 2 and Part 3, I shared Susan's experiences with illegal nursing home practices and lessons learned. This post summarized the lessons learned for easy reference. You may think you're admitted to the hospital but you may actually only be on observation status. Observation status does not qualify you for medicare coverage for a skilled nursing facility. Ask your nurse, doctor, or the admissions team if you are \"admitted\" or on \"observation status.\" Lesson 1: Rehab/nursing home stays are only covered by Medicare if a patient is first admitted to a hospital for 3 midnights.\nWhen they hear \"palliative care,\" most people think \"hospice\"--but this isn't quite correct. While hospice does include palliative care, palliative care is not limited to patients qualified for hospice. Palliative care focuses on relief from the symptoms of illness and addresses physical, emotional, and spiritual needs. Many hospital systems now employ palliative care specialists and some outpatient centers do as well. Some hospice organizations are offering palliative care services in the home to patients not qualified for hospice.\nUrinary Tract Infections (UTIs) are an infection anywhere in the urinary tract system, though we commonly think of them as bladder infections. For most younger adults, they are a simple infection that causes pain in the low pelvis, burning with urination and frequency. However, as we age, typical symptoms are different and the infections can be more serious. UTIs are a common source of infection in the elderly, ranked #2 after upper respiratory infections. If untreated, they can lead to infection of the kidneys (pyelonephritis), sepsis (overwhelming infection in the blood stream), and even death.", "pred_label": "__label__POS", "pred_score_pos": 0.6824291944503784}
{"content": "Agricultural production increasingly uses pesticides to control pests and other crop problems. Such products are, in general, toxic and leave residues in food and soil, contaminating not only groundwater, but also the food chain. On the other hand, there is a growing prospect of a healthier diet, organic farming, that has a high cost when compared to foods grown with synthetic chemicals.\nThrough an innovative technology, we intend to study economically and socially significant pests for agriculture in Brazil, with the aim of developing a specific biopesticide for local agriculture. We believe that our approach can represent a paradigm shift in the treatment of agricultural pests.", "pred_label": "__label__POS", "pred_score_pos": 0.630483865737915}
{"content": "The committee is also tasked with mitigating obstacles regarding the recall of unused spectrum, from state agencies for the National Broadcasting and Telecommunications Commission (NBTC), in exchange for compensation. It is expected to enhance cooperation between related agencies for 5G development support.\nDeputy prime ministers Somkid Jatusripitak, Prawit Wongsuwon and Wissanu Krea-ngam serve as the deputy chairmen of the committee. The minister of finance, minister of tourism and the minister of education are also part of the committee.\nThe permanent secretary for the Digital Economy and Society Ministry serves as the director and secretary of the committee.\nThis committee is formed to promote vertical 5G development, ensuring optimum benefits of 5G adoption for the economy and end users. It will promote a clear roadmap for 5G adoption and infrastructure development by ensuring the participation of representatives from key ministries, said Thailand NBTC secretary-general Takorn Tantasith.\nThe COVID-19 pandemic has prompted Thailand's major telecom operators to rev up deployment of 5G technologies. The country's top mobile operators are racing to deploy 5G networks at hospitals to support doctors and medical personnel to fight the virus.\n“Application of 5G to public health demonstrates how digital infrastructure can have a significant impact on people's health during a major emergency,” said Buddhipongse Punnakanta, Thailand Digital Economy and Society Minister.\nThe Digital Economy and Society Ministry, together with Huawei Technologies Thailand, are providing AI-assisted solutions with 5G technology to hospitals in the country with the aim of enabling output diagnosis results more efficiently through a high-speed network. Industrial organizations such as GSMA pointed out that 5G technologies are crucial in the fight against the pandemic and will be a “backbone” for the economic recovery. It is increasingly accepted in the industry that ICT and digital economy will be a major push as work resumes post pandemic.", "pred_label": "__label__POS", "pred_score_pos": 0.8038619756698608}
{"content": "Pfizer and BioNTech, the companies that recently announced their experimental coronavirus vaccine is 90% effective, has signed a distribution agreement with the European Union for 200 million doses of the vaccine.\nThe Hill reported that the European Commission would distribute the vaccine. In light of Pfizer’s vaccine trials and other companies such as Eli Lilly’s antibody treatment, many are hopeful a successful vaccine will be available by the middle of 2021.\n“Since the onset of the pandemic, Pfizer’s priority has been to develop a safe and effective vaccine, while simultaneously scaling up our manufacturing to deliver doses before the end of the year. This is an ambitious goal but critical to halting this global pandemic,” said Pfizer CEO Albert Bourla.\n“Today’s finalized supply agreement with the European Commission represents the largest initial order of vaccine doses for Pfizer and BioNTech to date and a major step toward our shared goal of making a COVID-19 vaccine available to vulnerable populations,” he added.\nMany European countries, faced with a second wave, has been initiating localized lockdowns.", "pred_label": "__label__POS", "pred_score_pos": 0.6424779295921326}
{"content": "IRS announces tax relief for Nebraska and Iowa disaster victims TAX ALERT |\nRecently, in separate notices, the IRS announced tax relief for taxpayers impacted by the recent winter storm that caused flooding in the Midwest. On March 22, the IRS published notice NE-2019-02, providing tax relief for regions of Nebraska impacted by the recent winter storm. Currently, the relief for regions in Nebraska is limited to Butler, Cass, Colfax, Dodge, Douglas, Nemaha, Sarpy, Saunders and Washington counties. On March 25, 2019, the IRS issued notice IA-2019-02, providing relief for Fremont, Harrison, Mills, Monona and Woodbury counties in Iowa.\nLike tax relief for other major disasters, these provisions also extend to taxpayers not located within the declared disaster area, but whose records necessary to meet a tax filing deadline are located within the impacted declared areas. Additionally, impacted taxpayers include workers assisting with the relief efforts who are affiliated with a recognized government or philanthropic organization. All qualifying taxpayers with an address outside of the impacted areas must contact the IRS at 866-562-5227.\nGrant of relief\nThe tax relief postpones various tax filing and payment deadlines due on or after March 9, 2019 and before July 31, 2019 for Nebraska locations and deadlines on or after March 12, 2019 and before July 31, 2019 for Iowa locations. As a result, affected individuals and businesses have until July 31, 2019 to file returns and pay any taxes that were originally due during this period. That includes upcoming tax year 2018 filings for calendar year taxpayers due on March 15, 2019 and April 15, 2019 as well as deadlines for making quarterly estimated tax payments. Specifically for impacted individual tax filers, the relief applies to their 2018 income tax returns that are otherwise due April 15, 2019. The relief also applies to tax-exempt organizations operating on a calendar-year basis that have a Form 990 due on May 15, 2019.\nIn affected Nebraska counties, the IRS will waive any late-deposit penalties for federal payroll and excise tax deposits normally due on or after March 9, 2019, and before March 25, 2019, if the deposits are made by March 25, 2019. In affected Iowa counties, the IRS will waive any late-deposit penalties for federal payroll and excise tax deposits normally due on or after March 12, 2019, and before March 27, 2019, if the deposits are made by March 27, 2019\nThe IRS automatically provides filing and penalty relief to any taxpayer with an IRS address of record located in the disaster area. Thus, taxpayers need not contact the IRS to get this relief. However, if an affected taxpayer receives a late filing or late payment penalty notice from the IRS that has an original or extended filing, payment or deposit due date falling within the postponement period, the taxpayer should call the number on the notice to have the penalty abated.\nThese declarations also trigger special provisions that give affected taxpayers the option of claiming disaster-related casualty losses on their federal income tax return either in the year the event occurred or in the preceding tax year. While personal casualty losses are no longer deductible beginning with the 2018 tax year as a result of tax reform, personal casualty losses attributable to a federally declared disaster may be claimed as a qualified disaster loss. See Publication 547 for details.", "pred_label": "__label__POS", "pred_score_pos": 0.5593831539154053}
{"content": "Abstract\nCaco-2, a human differentiated intestinal epithelial cell line, is a promising model for investigating the mechanism of polarized targeting of apical and basolateral membrane proteins. We stably transfected rat GLUT5 cDNA and rabbit GLUT1 cDNA into Caco-2 cells with an expression vector. Immunohistochemical study revealed that the GLUT5 protein expressed was localized at apical membranes and that the GLUT1 expressed was present primarily in the basolateral membranes of cells grown on permeable support. Next, to investigate the domain responsible for determining apical vs. basolateral sorting in glucose transporters, we prepared several GLUT1-GLUT5 chimeric cDNAs and transfected them into Caco-2 cells. A GLUT1 [N terminus- sixth transmembrane domain (TM6)]-GLUT5 [intracellular loop (IL)~C terminus] chimera was observed exclusively at the apical membrane, while GLUT1 (N terminus~IL)-GLUT5 (TM7~C terminus) and GLUT1 (N terminus~TM12)-GLUT5 (C- terminal domain) chimeras were observed mainly at the basolateral membrane, a localization similar to that of GLUT1. Moreover, using a recombinant adenovirus expression system, we expressed a GLUT5 (N terminus~TM6) - GLUTI(IL)-GLUTS(TM7~C-terminus)chimera, which was observed at the basolateral membrane. Based on these results, the C-terminal domain does not determine isoform-specific targeting of GLUT1 and GLUT5. Rather, it is the intracellular loop in glucose transporters that appears to play a pivotal role in apical-basolateral sorting signals in Caco-2 cells.\nASJC Scopus subject areas Molecular Biology Endocrinology", "pred_label": "__label__POS", "pred_score_pos": 0.9993372559547424}
{"content": "We used to plan all the learning experiences in advance. If the entire unit is planned out in detail, where are the opportunities for learners to drive the inquiry? How do they take ownership of their learning and lead it in new directions?\nWe do, at my school, plan the big picture, of course. We build on where the learners have come from and ensure clarity on the conceptual direction. We know what we hope the learners will come to understand and the skills and dispositions required to support the learning. But plans are flexible and responsive to what the learners reveal. The individuality of the journey, the specific teachable moments, and the ways the learning might impact or transform each learner, depend on how the inquiry unfolds.\nAs we shift to an increasingly emergent model, the learning is becoming more meaningful. The more we take an inquiry stance, seeking to notice what our learners are curious about and how best they learn, the more competently we can support them in moving forward. The more thoughtfully we reflect on what is revealed, the more effectively we can respond.\nWhen questioned recently about our strategic plan, I realised that this is also how we, as leaders at my school, plan. We know where we have come from and we can identify goals for moving ahead. And then what? We value the power of ‘what if’ and ‘how might we’ questions to provoke thinking, encourage dreaming and support our inquiry stance.\nHere too, it seems our model is more emergent. The more attentively we observe and notice ourselves and others, the more we are able to explore possibilities. The more thoughtfully we reflect on the nuances of complex issues, openly examine tensions and actively disrupt the status quo, the more ready we are to experiment with innovative solutions.\nCreating a carefully laid out action plan in advance, with specific strategies and tasks, is not, it seems, our optimum style.", "pred_label": "__label__POS", "pred_score_pos": 0.696468710899353}
{"content": "The Business Auto Policy typically extends Liability coverage to all Corporate Employees for vehicles Hired or Borrowed by the\nName Insured (generally a Corporation). Your Business Auto Policy will function in excess of the Hired or Borrowed vehicle’s insurance. However, Liability coverage is not extended to any employees (frequently Officers/Owners) when they or their spouse borrow or rent a vehicle for their personal use. A coverage gap occurs if they do not have vehicles registered in their personal names or that of their spouse as they then have no Personal Automotive Policy coverage to respond. This same exclusion of coverage would apply to Uninsured/Underinsured Motorist coverage also.\nTypically, many people tend to rent vehicles while on vacation, generally in their personal names. If this occurs, the individual is relying on the limits provided by the Rental Company. We strongly suggest that Owners/Executives consider the addition of Drive Other Car Coverage, which will allow the Corporate Automobile limits to follow them if they\nRent or Borrow a vehicle in their personal name within the United States, its Territories and Possessions, Puerto Rico and Canada.\nThe cost varies per Company but generally is in the $250 range for each individual designated on the Commercial Auto Policy.\nIf this exposure exists, we strongly suggest that you consider this coverage. Please contact your Agent or Customer Service Representative if you desire more information.", "pred_label": "__label__POS", "pred_score_pos": 0.8526030778884888}
{"content": "Giant Microbes Original Measles Morbillivirus\nFACTS: Measles, sometimes known as rubeola, is a well-known, highly contagious virus. Although its telltale symptoms are body-covering red spots often accompanied by a mild fever, it is in fact a respiratory disease that can lead to life-threatening conditions such as pneumonia and encephalitis (or brain swelling and degeneration). And indeed, in countries where malnutrition and poor health are prevalent, measles infections can be fatal.\nThe good news is that in 1963 scientists synthesized a vaccine from a live rubeola virus, and nearly all children in the developed world are now inoculated against measles, typically along with mumps and rubella when they receive their MMR shot. (A vaccine against varicella, the virus which causes chickenpox, is now often included in the shot, making it the MMRV.)\nHowever, in developing nations that lack widespread vaccination programs, measles remains a significant health threat. Indeed, the World Health Organization calls measles one of the leading causes of vaccine-preventable childhood death.\nFortunately, international efforts to vaccinate against measles are having a significant impact upon the incidence of measles worldwide. As global vaccination campaigns continue, additional lives will be saved.\n(Measles is nicht to be confused with German measles vich is caused by a completely different wirus.)", "pred_label": "__label__POS", "pred_score_pos": 0.9982457160949707}
{"content": "Applications are being invited for arts, museums and libraries projects that engage people in England with arts and culture.\nAfter suspending the National Lottery Project Grants programme in March 2020 due to the coronavirus/COVID-19 crisis, Arts Council England is re-opening the programme for applications today, aiming to support individuals and organisations to get activities up and running again.\nApplications are accepted for grants of between £1,000 and £100,000. The total amount of funding available between July 2020 and April 2021 is £59.8 million.\nThe grants can support a broad range of activities, ranging from projects that directly create and deliver creative and cultural activity and content for audiences, visitors and digital users, to those that have a longer term impact on strengthening the sector, such as organisational development, research and development and sector support.\nDue to the impact that the coronavirus pandemic has had on the arts sector, the Arts Council is particularly keen to support:\nMost of the criteria of the programme have remained the same as they were before it was suspended but the Arts Council has removed the requirement for a minimum 10% match funding until further notice, taking into account that artists and organisations are struggling to secure any additional funding under the present circumstances. Additionally, some changes were made which were already due to launch before the programme was suspended. Most notably, public libraries can now apply for grants to deliver activities addressing any one of the four Universal Library Offers (Creativity and Culture; Reading; Information and Digital; Health and Wellbeing).\nApplications will be accepted on an ongoing basis from 22 July 2020 onwards.", "pred_label": "__label__POS", "pred_score_pos": 0.9179147481918335}
{"content": "Individuals who face mounting debts such as student loans may qualify to have these debts discharged after filing for bankruptcy. Being absolved of these financial obligations can occur only if the debtor proves that the debt will result in undue hardship for both him and his dependents. As any bankruptcy attorney will attest, proving your undue hardship rests upon three key factors:\n1. A debtor cannot maintain a minimal standard of living based on his current income and expenses. If a judge decides to release you from your debt, you must first prove that your attempt to repay it will result in a severe negative impact to your quality of life. Only if evidence that supports this claim is provided will the court then consider the remaining undue hardship qualifications. 2. Current circumstances indicate that for the duration of the repayment period, or a significant portion of it, the debtor will continue to experience hardship if forced to maintain his debt. Many bankruptcy lawyers consider this to be the hardest factor to prove. Basically, a judge must be persuaded that, over the duration of your repayment period, you will not experience a significant change in lifestyle or income level that will allow you to more easily resolve your debt. However, if you can successfully argue this point, you have only one more obstacle to overcome in proving your undue hardship. 3. The debtor has made a good-faith effort to repay his debt. Have you tried to pay off your debt? Can you show the judge proof of your past efforts to maintain and reduce your debt? If so, you have effectively made your case for undue hardship. At this point, should the judge decide in your favor, you would be released from all further responsibilities in paying off your debt.\nDo you qualify for undue hardship? The bankruptcy law firm of Cutler & Associates, Ltd. can help you to determine whether you are eligible for having some or all of your debt discharged after declaring bankruptcy.", "pred_label": "__label__POS", "pred_score_pos": 0.9732112288475037}
{"content": "Dollar reached a 14-year high\nFollowing the US election results and Donald Trump’s win, the market is speculative about the US economic growth outlook as well as the timing of a US interest rate hike, considering Trump’s protectionist policies.\nTrump has announced that he will spend $1 trillion on infrastructure construction. This spending, along with a reduction in taxes, is likely to give trade restrictions as well as the economy a significant boost, which could fuel inflation. Trump’s inflationary policies, combined with the already hawkish Federal Reserve, points to higher interest rates in the future. These sentiments have led to the upward trajectory of the US dollar (UUP), which reached a 14-year high on November 16, 2016.\nTech sector’s vulnerability to US dollar fluctuations\nThe above chart shows that IBM generates more than half of its revenue from outside the United States. Apart from IBM, Oracle (ORCL), Symantec (SYMC), and Microsoft (MSFT) are some of the leading technology players that derive a majority of their revenues from regions outside the United States. These regions include the EMEA (Europe, the Middle East, and Africa) and the Asia-Pacific. As a result, their top lines are significantly impacted by the appreciating US dollar.\nApart from significant revenue generation, cash parked overseas adds to these companies’ vulnerabilities to currency fluctuations.\nLater in this series, we’ll discuss the growing cash reserves in the tech sector.", "pred_label": "__label__POS", "pred_score_pos": 0.8473418951034546}
{"content": "(1 Samuel 2:30 ESV) “… for those who honor me I will honor …” If you have ever watched the movie “Chariots of Fire”, you may remember the scene where Eric Liddell, a Scottish runner for Great Britain, is about to run the 400 meter race in the 1924 Olympics in Paris. Most people are doubtful of Liddell’s ability to when this race. In the film, just before the race begins, Jackson Scholz – an American runner, hands Liddell a note; “It says in the good Book, ‘He that honors me, I will honor.’ Good luck.” (Actually, the note was sent by Eric Liddell’s teammates, but this is movie history.) As real history records, Eric Liddell went on to win the race. Let us consider what God is saying in the phrase, “for those who honor me I will honor.” God is justly jealous of His honor. He would not be God if He was to part with one molecule of His attributes. Thus, to honor God is to trust Him to be all that He says He is. We must totally trust in God’s divinity and His revealed Word. Doubt dishonors God and His Word. As Christians, we must beware of those who hold low views of biblical inspiration, as well as those who tamper with the meaning of Scripture. Christians should stand in awe of God’s divinity and bow unquestioningly to His Authority and Word as found in the Bible. As we honor God, He honors us by making His Word a light in the darkness of difficult times. (Psalm 119:105) Honor God’s Word and it will guide you in life, support you in death, and take you to heaven. Honor God’s Word and He will honor you by making that Word the joy of your soul. Paul writes, “Let the word of Christ dwell in you richly, teaching and admonishing one another in all wisdom, singing psalms and hymns and spiritual songs, with thankfulness in your hearts to God.” (Colossians 3:16 ESV) Christians are to pursue a God-honoring faith that rests in Him with a childlike and unquestioning confidence. Faith that honors God is a faith that relies on His power to complete all that He has pledged in His covenant and Word to perform. We honor Him by our unhesitating trust in His power, faithfulness, and love. The Scriptures teach us that, “You keep him in perfect peace whose mind is stayed on you, because he trusts in you. Trust in the Lord forever, for the Lord God is an everlasting rock.” (Isaiah 26:3-4 ESV) The faith that honors God is believing His promises when they are not yet fulfilled; that He will answer our prayers although they are not yet answered; and that He cares for us even when there is no evidence of that care; that faith will be honored by Him. Honor Christ! What a dishonor it would be to our Savior to doubt the effectiveness of His blood to pardon and that of His righteousness to justify the very chief of sinners. God honors us with His grace when we do not deserve it. “For the wages of sin is death, but the free gift of God is eternal life in Christ Jesus our Lord.” (Romans 6:23 ESV) Genuineness of faith will ultimately result in the praise, glory, and honor of God through Jesus Christ our Lord. (1 Peter 1:7 ESV)", "pred_label": "__label__POS", "pred_score_pos": 0.8402359485626221}
{"content": "However, toothbrushing, flossing, or using oral rinses did not a make significant difference in whether those living in the same house became infected. Despite many people taking known infection control measures such as sanitizing toothbrushes and not sharing toothbrushes and toothpaste tubes, some cross-infection occurred, the authors wrote.\n\"This result can be interpreted to indicate the tongue as the main oral organ acting as a reservoir of COVID-19 and the importance of brushing to decrease the viral load of the individual carrier,\" wrote the group, led by María José González‑Olmo of the dentistry department at Rey Juan Carlos University in Madrid.\nHabits of housemates\nGlobal efforts to contain SARS-CoV-2, the virus that causes COVID-19, include maintaining good hygiene, keeping a safe distance from others, and sanitizing surfaces. Preliminary research has suggested that the mouth is a robust site for infection and transmission of the virus, and other evidence has indicated that maintaining good oral hygiene also may stop the spread. Here, researchers aimed to determine whether misuse of dental hygiene would facilitate the spread of COVID-19 among people living together.\nApproximately 300 people living in Spain were sent an online questionnaire in April 2020, approximately four weeks after the country was locked down due to the pandemic. All respondents lived with and shared a bathroom with another person. Approximately 170 people were cross-infected from housemates, the researchers found.\nRoutines that may matter most\nApproximately 34% of all participants reported that they brushed their teeth two or more times daily, about 20% flossed every day, about 15% used a daily rinse, and about 17% brushed their tongue every day. Tongue brushing was used more among those without transmission of the disease to other members of their households (t = 2.202; p = 0.029).\nOf those in the cross-infected group, 127 shared toothbrush containers and 43 did not. In the group with no cross-infection, 65 shared brush containers and 67 didn't. Only a small segment of both groups disinfected their brushes with bleach daily. A total of 276 participants didn't disinfect their brushes. Of the 25 people who sanitized their brushes, about one-third still became infected with the novel coronavirus. In addition, about 5% of the cross-infected group (eight people) shared their toothbrush with someone they lived with. Of those who didn't get infected, only one shared a toothbrush.\nThe study had some limitations, according to the authors. For example, the data were self-reported, and the aerosol and surface viability of SARS-CoV-2 at the participants' homes could not be measured due to lockdowns.\nEncourage good habits\nNevertheless, dentists should encourage patients to maintain good oral hygiene, including flossing and tongue brushing, and to avoid actions like toothbrush sharing or storing brushes with others.\n\"The use of inappropriate measures in the dental environment could contribute to the indirect transmission of COVID-19 between cohabitants,\" they wrote.\nCopyright © 2020 DrBicuspid.com", "pred_label": "__label__POS", "pred_score_pos": 0.6540054082870483}
{"content": "Notre boutique utilise des cookies pour améliorer l'expérience utilisateur et nous vous recommandons d'accepter leur utilisation pour profiter pleinement de votre navigation.\nJ'accepte\nThis paper investigates the degree to which victims of Sexual and Gender Based Violence (SGBV)1 access justice in Rwanda.\nThis study has used three main methods. The desk review has been used to explore and extract secondary data from laws, policy documents, studies and administrative and specialized reports. Interviews and focus group discussions have been conducted with key informants to gain first hand materials and insights. The findings suggest that Rwanda has achieved impressive progress in relation to the improvement of the legal and policy frameworks. The country has put in place an equally supportive institutional structure. However, access to justice for victims of SGBV is still complicated due to several practical reasons, including persistent legal gaps, limited capacity among service provider structures and staff and the lack of evidence for many cases related to SGBV.\nDr Aggée M.\nShyaka Mugabe is a Senior Lecturer and Senior Researcher at the Centre for Conflict Management of the University of Rwanda. He holds a PhD in Political ans Social Sciences from the Université Catholique de Louvain, Belgium (2005-2009). He has completed a postdoctorate fellowship at the School of Global Studies (SGS), Sweden.\nAttention : dernières pièces disponibles !\nDate de disponibilité:", "pred_label": "__label__POS", "pred_score_pos": 0.7633639574050903}
{"content": "to make a booking at one of our South Auckland clinics\n*Please read our online booking terms and conditions carefully before booking\nShin Splints\nJanuary 17, 2017\nThe term \"shin splints\" refers to pain along the shin bone (also known as the tibia) — the large bone in the front of your lower leg. Shin splints are common in runners, dancers and military recruits. Medically known as medial tibial stress syndrome, shin splints often occur in athletes who have recently intensified or changed their training routines. The increased activity overworks the muscles, tendons and bone tissue.\nMost cases of shin splints can be treated with rest, ice and other self-care measures. Wearing proper footwear and modifying your exercise routine can help prevent shin splints from recurring. Your podiatrists can advise you on this, and our podiatrists who specialize in myofascial release and kinesio taping can assist with the healing.\nShin Splints are not a condition covered by ACC as it is an overuse injury and is not from a direct incident.", "pred_label": "__label__POS", "pred_score_pos": 0.8499538898468018}
{"content": "NEW YORK (TheStreet) --\nBarrick Gold ( ABX) stock is declining by 1.68% to $6.45 in early morning trading on Friday, as gold prices retreat after Federal Reserve Chairwoman Janet Yellen indicated in a speech yesterday that the central bank will hike interest rates before the year ends.\nDuring a speech at the University of Massachusetts on Thursday afternoon, Yellen said that an interest rate increase could happen in 2015. The Fed's two remaining meetings this year are scheduled for October and December.\nThe assurance of an upcoming interest rate hike has strengthened the dollar and consequently weighed on gold prices, as dollar-traded gold becomes more expensive to foreign buyers,\nThe Wall Street Journal reports.\nHowever, increased seasonal demand for gold from China in October to February should reverse some of the commodity's losses in upcoming months, according to\nThe Journal.\nGold for December delivery is lower by 0.62% to $1,146.70 per ounce on the COMEX this morning.\nBarrick Gold is a gold mining company based in Toronto, Canada.\nSeparately, TheStreet Ratings team rates BARRICK GOLD CORP as a Sell with a ratings score of D. TheStreet Ratings Team has this to say about their recommendation:\nWe rate BARRICK GOLD CORP (ABX) a SELL. This is driven by some concerns, which we believe should have a greater impact than any strengths, and could make it more difficult for investors to achieve positive results compared to most of the stocks we cover. The company's weaknesses can be seen in multiple areas, such as its generally high debt management risk, disappointing return on equity and generally disappointing historical performance in the stock itself.\nHighlights from the analysis by TheStreet Ratings Team goes as follows:\nThe debt-to-equity ratio of 1.26 is relatively high when compared with the industry average, suggesting a need for better debt level management. The company's current return on equity has slightly decreased from the same quarter one year prior. This implies a minor weakness in the organization. Compared to other companies in the Metals & Mining industry and the overall market, BARRICK GOLD CORP's return on equity significantly trails that of both the industry average and the S&P 500. ABX's stock share price has done very poorly compared to where it was a year ago: Despite any rallies, the net result is that it is down by 57.91%, which is also worse that the performance of the S&P 500 Index. Investors have so far failed to pay much attention to the earnings improvements the company has managed to achieve over the last quarter. Naturally, the overall market trend is bound to be a significant factor. However, in one sense, the stock's sharp decline last year is a positive for future investors, making it cheaper (in proportion to its earnings over the past year) than most other stocks in its industry. But due to other concerns, we feel the stock is still not a good buy right now. Despite the weak revenue results, ABX has significantly outperformed against the industry average of 45.0%. Since the same quarter one year prior, revenues slightly dropped by 9.2%. The declining revenue has not hurt the company's bottom line, with increasing earnings per share. 41.46% is the gross profit margin for BARRICK GOLD CORP which we consider to be strong. Regardless of ABX's high profit margin, it has managed to decrease from the same period last year. You can view the full analysis from the report here: ABX", "pred_label": "__label__POS", "pred_score_pos": 0.5417684316635132}
{"content": "The U.S. private sector added 200,000 jobs in September, which beat economists' expectations and has fueled speculation that the\nFederal Reserve will hike interest rates before year end, Reuters reports.\nHigher interest rates would likely strengthen the dollar, and a stronger dollar would weigh on demand for gold as the precious metal's relative cost would increase for foreign buyers.\n\"The dollar's rise has been a wrecking ball for commodity-sensitive assets this year,\" Ken Ford, president of\nWarwick Valley Financial Advisors, told MarketWatch.\nGold for December delivery is sliding by 1.14% to $1,114.20 per ounce on the COMEX this afternoon.\nSeparately, TheStreet Ratings team rates YAMANA GOLD INC as a Sell with a ratings score of D. TheStreet Ratings Team has this to say about their recommendation:\nWe rate YAMANA GOLD INC (AUY) a SELL. This is driven by several weaknesses, which we believe should have a greater impact than any strengths, and could make it more difficult for investors to achieve positive results compared to most of the stocks we cover. The company's weaknesses can be seen in multiple areas, such as its feeble growth in its earnings per share, deteriorating net income, disappointing return on equity, weak operating cash flow and generally disappointing historical performance in the stock itself.\nHighlights from the analysis by TheStreet Ratings Team goes as follows:\nYAMANA GOLD INC has experienced a steep decline in earnings per share in the most recent quarter in comparison to its performance from the same quarter a year ago. The company has suffered a declining pattern earnings per share over the past two years. During the past fiscal year, YAMANA GOLD INC reported poor results of -$1.35 versus -$0.59 in the prior year. The company, on the basis of change in net income from the same quarter one year ago, has significantly underperformed when compared to that of the S&P 500 and the Metals & Mining industry. The net income has significantly decreased by 254.9% when compared to the same quarter one year ago, falling from $5.10 million to -$7.90 million. Return on equity has greatly decreased when compared to its ROE from the same quarter one year prior. This is a signal of major weakness within the corporation. Compared to other companies in the Metals & Mining industry and the overall market, YAMANA GOLD INC's return on equity significantly trails that of both the industry average and the S&P 500. Net operating cash flow has decreased to $121.80 million or 17.98% when compared to the same quarter last year. In addition, when comparing the cash generation rate to the industry average, the firm's growth is significantly lower. Despite any intermediate fluctuations, we have only bad news to report on this stock's performance over the last year: it has tumbled by 73.48%, worse than the S&P 500's performance. Consistent with the plunge in the stock price, the company's earnings per share are down 150.00% compared to the year-earlier quarter. Naturally, the overall market trend is bound to be a significant factor. However, in one sense, the stock's sharp decline last year is a positive for future investors, making it cheaper (in proportion to its earnings over the past year) than most other stocks in its industry. But due to other concerns, we feel the stock is still not a good buy right now. You can view the full analysis from the report here: AUY", "pred_label": "__label__POS", "pred_score_pos": 0.8077682256698608}
{"content": "2nd reading of ordinance allowing the keeping of chickens (hens) with some limitations. Given this is the second reading and the first was passed unanimously, this is being placed on the consent calendar. Consideration of establishment of ad-hoc committee to work on updating Town Center Specific Plan. This would consist of approving RFPs to go out to various vendors. Revisiting the Town Center Specific Plan for potential updates was one of the Council goals for 2019. While an RFP does not result in any cash outlays, if we were to move forward on any actual updates there would likely be a significant cost.\nBecause updates to the plan happen so infrequently and there are a great many laws that govern what can and cannot be included in a plan like this, the city is not staffed to handle this type of work with existing resources. As a result, if the City wishes to update this plan, it will likely have to engage in outside consultants who have professional expertise in this area.\nTo engage outside vendors for a project of this nature, we would send out a Request for Proposal (RFP) which gives guidelines and asks respondents to propose services to the city. Upon reviewing the responses, the level of services offered and an approximate price, the city may make a decision on whether or not to engage those services.\nIt would be a long process and involve significant staff time and public input and discussion. Doing something like this could be the first step in collectively deciding what the vision for our downtown will be. I was glad to be a voice advocating for this to be included as one of the Council goals this year.\nIf you have any thoughts or questions about any of these items please comment or contact me and I'll do my best to respond or find out more and report back.", "pred_label": "__label__POS", "pred_score_pos": 0.8201111555099487}
{"content": "The inability to lose weight despite increasing exercise and decreasing caloric intake may be due to low thyroid levels. An underactive thyroid gland can drastically slow down your metabolism, making weight loss a near impossibility. Without correcting thyroid levels, if you're suffering from an underactive thyroid, also known as hypothyroidism, you may continually struggle with your weight, not only having difficulty losing weight but also potentially gaining while you are working hard to lose it. Alternatively, an overactive thyroid gland, also known as hyperthyroidism, can drastically speed up the metabolism, causing the body to burn calories at a faster-than-normal rate resulting in unexplained weight loss.\nThis site offers information designed for educational purposes only. You should not rely on any information on this site as a substitute for professional medical advice, diagnosis, treatment, or as a substitute for, professional counseling care, advice, diagnosis, or treatment. If you have any concerns or questions about your health, you should always consult with a physician or other healthcare professional.", "pred_label": "__label__POS", "pred_score_pos": 0.9894583821296692}
{"content": "A new report finds that active enforcement against foreign bribery significantly decreased since 2018.\nThe best maritime news and insights delivered to your inbox bi-weekly. Here's what you can expect from us: News & key insights covering the maritime industry Expert analysis and opinions on maritime corruption and more Exclusive interviews Subscribe to Maritime Fairtrade\n*Maritime Fairtrade newsletter is 100% free, and you can always unsubscribe with one click.", "pred_label": "__label__POS", "pred_score_pos": 0.6048463582992554}
{"content": "When I started my first corporate level marketing position, I determined to “always only add.” I decided I was going to use my hands to build, not tear down, and that no matter who I worked with, I only wanted to add – no matter what.\nOne day, a man on my team (who passed a lot of judgment), was eating cake at a small birthday celebration at work. At the party, he told someone they were “living a sedentary life” and to “mind what you eat.” Later, when he passed my desk and fell into his chair saying, “Whew, I’m tired,” I wanted to respond, “Passing all that judgment can wear you out!” But I didn’t; instead I started drafting an email to a coworker about it.\nWhile typing, I glanced at the only hot-pink sticky hanging around my monitors. “If I sent this,” I thought, “all I am doing is stirring up an ‘us-against-them’ mentality in a team environment.” I wasn’t looking at the good, I wasn’t building a relationship or respect – I wasn’t adding anything.\nI don’t have to like everyone, but I do have to love everyone. People are people, and I am no greater. If I am going to love them, I need to love them all the time. God wants to and can use us at all moments, in every moment. At all times, I need to remember: if I am not adding, I am in the way.\nI deleted the email.\nGinny’s Idea\nIs there a goal you want to keep in mind at your workplace? Create your own post-it note to remind you along the way.", "pred_label": "__label__POS", "pred_score_pos": 0.7637190818786621}
{"content": "Olya Mastikhina, Byeong-Ui Moon, Kenneth Williams, Rupal Hatkar, Dakota Gustafson, Xuetao Sun, Margaret Koo, Alan Y.L. Lam, Yu Sun, Jason E. Fish, Edmond W.K. Young, ORCID ProfileSara S. Nunes\nWhile interstitial fibrosis plays a significant role in heart failure, our understanding of disease progression in humans is limited. To address this limitation, we have engineered a cardiac-fibrosis-on-a-chip model consisting of a microfabricated device with live force measurement capabilities using co-cultured human cardiac fibroblasts and pluripotent stem cell-derived cardiomyocytes. Transforming growth factor-β was used as a trigger for fibrosis. Here, we have reproduced the classic hallmarks of fibrosis-induced heart failure including high collagen deposition, increased tissue stiffness, BNP secretion, and passive tension. Force of contraction was significantly decreased in fibrotic tissues that displayed a transcriptomic signature consistent with human cardiac fibrosis/heart failure. Treatment with an anti-fibrotic drug decreased tissue stiffness and BNP secretion, with corresponding changes in the transcriptomic signature. This model represents an accessible approach to study human heart failure in vitro, and allows for testing anti-fibrotic drugs while facilitating the real-time assessment of cardiomyocyte function.", "pred_label": "__label__POS", "pred_score_pos": 0.9746827483177185}
{"content": "PROJECT DOCUMENT REPOSITORY\nDuring sustained periods of drought, landholders have come to appreciate the quality and persistence of native grasses under stress compared to non-native pasture species. How we manage these pastures is therefore essential to maintaining a productive and profitable livestock industry in NSW\n1998 - 2005\nBiological Control of Scotch Thistle and Paterson’s Curse\n2015\nGetting to the root cause of pasture legume (subclover) decline in NSW\n2015 - 2017\nYield Prophet: Matching crop inputs with potential yield in Harden\nAcknowledgements\nThis project was conducted by the Binalong Landcare Group (a subgroup of HMLG), with technical support from South East Local Land Services and NSW Department of Primary Industries (DPI).", "pred_label": "__label__POS", "pred_score_pos": 0.9980451464653015}
{"content": "Friday, August 14, 2020\nDebbie Guerra, executive vice president at ACI Worldwide, observed that criminals are exploiting the card-not-present (CNP) space, especially buy online/pick up in store (BOPIS) and click-and-collect payment methods. \"Fraudsters are targeting higher value items like electronics and luxury brand names, especially within newer channels such as curbside pick-up and in-parking lot pick-up,\" she said. \"We continue to see a huge increase above industry averages in eCommerce sales year over year.\"\nWill LaSala, security evangelist at OneSpan, has also seen a sharp increase in phishing attacks and new account takeovers during the COVID-19 crisis. \"We can attribute up to $77 million caused by COVID-related attacks,\" he said. \"Account takeover rose to the top during COVID and phishing attacks are up by 667 percent, making a huge impact across the board.\"\nGuerra further noted that ecommerce activity was up by 19 percent during July 2020 compared to the previous year. ACI's findings were based on hundreds of millions of ecommerce transactions from the company's global merchant base. Notably, the data revealed a sharp uptick in the outdoor items category, which rose from 9 percent in 2019 to 12 percent in 2020.\nFollowing are additional data points from the ACI study:\n\"We continue to see a huge increase above industry averages in ecommerce sales year over year,\" Guerra added. \"As more brick-and-mortar stores reopen with COVID restrictions, we are seeing card-present transactions slightly increase; however, we expect the ecommerce trend to continue post-COVID as consumers experience the convenience and speed of digital payments.\"\nLaSala mentioned that he has seen similar trends in the banking sector, where account takeover attacks have increased by 72 percent, much of it related to federal relief programs such as the Payroll Protection Plan, stimulus checks and unemployment benefits. Also, the Dark Web has made a huge cache of personally identifiable information available to fraudsters and array of tools designed to help them initiate new attacks.\n\"People mistakenly think of fraudsters as guys in hoodies who perpetrate crimes from their basements,\" LaSala said. \"In reality, cybercrime is a well-organized global enterprise.\" For example, there are specialists within the multilayered threat landscape whose sole focus is writing attacks and designing email templates, he stated, while others purchase and use these products to launch attacks.\nThe criminals who design attacks are inventive and agile, LaSala noted. \"They leverage the products by making a few simple tweaks and using them again,\" he said. \"Through the years, we've seen reused and redeployed variants. That's why we recommend a holistic, multilayered approach that uses application shielding, dynamic passwords and artificial intelligence to protect mobile and cloud environments.\"\nThe Green Sheet Inc. is now a proud affiliate of Bankcard Life, a premier community that provides industry-leading training and resources for payment professionals. Click here for more information.\nNotice to readers: These are archived articles. Contact names or information may be out of date. We regret any inconvenience.", "pred_label": "__label__POS", "pred_score_pos": 0.7299029231071472}
{"content": "The continued Covid-19 situation poses huge challenges regarding labor issues, personal data processing, public health, contracts, corporate governance, tax obligations and sanctions-related matters. This raises substantial questions and concerns from a tax and legal point of view. WTS Global, GTM’s international tax network, has compiled a 50+ country overview of information and guidance for multinational organizations on managing the evolving impacts of Covid-19.\n[last updated October 2020]", "pred_label": "__label__POS", "pred_score_pos": 0.9999135732650757}
{"content": "Abstract : This contribution explores, within a critical narrative analysis framework, the changing role and in fact the gradual erasure of the linguist and the sociolinguist as a figure or character in the Occitan activist discourse. It seeks to draw parallels between this phenomenon and the concomitant development of the presence of the medical profession within that discourse, and to establish connections with a new interest for language transmission in the home. Parallel developments can be observed in Wales and other territories where a minority language is spoken, and beyond the erasure of the linguist as a figure, it questions the role of the individual and the collective in language revitalisation.", "pred_label": "__label__POS", "pred_score_pos": 0.638043999671936}
{"content": "During the Space Telescope and Optical Reverberation Mapping Project (STORM)observations of NGC 5548, the continuum and emission-line variability becamede-correlated during the second half of the 6-month long observing campaign.Here we present Swift and Chandra X-ray spectra of NGC 5548 obtained as a partof the campaign. The Swift spectra show that excess flux (relative to apower-law continuum) in the soft X-ray band appears before the start of theanomalous emission-line behavior, peaks during the period of the anomaly, andthen declines. This is a model-independent result suggesting that the softexcess is related to the anomaly. We divide the Swift data into on- andoff-anomaly spectra to characterize the soft excess via spectral fitting. Thecause of the spectral differences is likely due to a change in the intrinsicspectrum rather than being due to variable obscuration or partial covering. TheChandra spectra have lower signal-to-noise ratios, but are consistent withSwift data. Our preferred model of the soft excess is emission from anoptically thick, warm Comptonizing corona, the effective optical depth of whichincreases during the anomaly. This model simultaneously explains all the threeobservations: the UV emission line flux decrease, the soft-excess increase, andthe emission line anomaly.\nWe present the results of an optical spectroscopic monitoring programtargeting NGC 5548 as part of a larger multi-wavelength reverberation mappingcampaign. The campaign spanned six months and achieved an almost daily cadencewith observations from five ground-based telescopes. The H$\\beta$ and He II$\\lambda$4686 broad emission-line light curves lag that of the 5100 $\\AA$optical continuum by $4.17^{+0.36}_{-0.36}$ days and $0.79^{+0.35}_{-0.34}$days, respectively. The H$\\beta$ lag relative to the 1158 $\\AA$ ultravioletcontinuum light curve measured by the Hubble Space Telescope is roughly$\\sim$50% longer than that measured against the optical continuum, and the lagdifference is consistent with the observed lag between the optical andultraviolet continua. This suggests that the characteristic radius of thebroad-line region is $\\sim$50% larger than the value inferred from optical dataalone. We also measured velocity-resolved emission-line lags for H$\\beta$ andfound a complex velocity-lag structure with shorter lags in the line wings,indicative of a broad-line region dominated by Keplerian motion. The responsesof both the H$\\beta$ and He II $\\lambda$4686 emission lines to the drivingcontinuum changed significantly halfway through the campaign, a phenomenon alsoobserved for C IV, Ly $\\alpha$, He II(+O III]), and Si IV(+O IV]) during thesame monitoring period. Finally, given the optical luminosity of NGC 5548during our campaign, the measured H$\\beta$ lag is a factor of five shorter thanthe expected value implied by the $R_\\mathrm{BLR} - L_\\mathrm{AGN}$ relationbased on the past behavior of NGC 5548.\nDuring an intensive Hubble Space Telescope (HST) Cosmic Origins Spectrograph(COS) UV monitoring campaign of the Seyfert~1 galaxy NGC 5548 performed from2014 February to July, the normally highly correlated far-UV continuum andbroad emission-line variations decorrelated for ~60 to 70 days, starting ~75days after the first HST/COS observation. Following this anomalous state, theflux and variability of the broad emission lines returned to a more normalstate. This transient behavior, characterised by significant deficits in fluxand equivalent width of the strong broad UV emission lines, is the first of itskind to be unambiguously identified in an active galactic nucleus reverberationmapping campaign. The largest corresponding emission-line flux deficitsoccurred for the high-ionization collisionally excited lines, C IV and Si IV(+OIV]), and also He II(+O III]), while the anomaly in Ly-alpha was substantiallysmaller. This pattern of behavior indicates a depletion in the flux of photonswith E_{\\rm ph} > 54 eV, relative to those near 13.6 eV. We suggest twoplausible mechanisms for the observed behavior: (i) temporary obscuration ofthe ionizing continuum incident upon BLR clouds by a moving veil of materiallying between the inner accretion disk and inner BLR, perhaps resulting from anepisodic ejection of material from the disk, or (ii) a temporary change in theintrinsic ionizing continuum spectral energy distribution resulting in adeficit of ionizing photons with energies > 54 eV, possibly due to a transientrestructuring of the Comptonizing atmosphere above the disk. Current evidenceappears to favor the latter explanation.", "pred_label": "__label__POS", "pred_score_pos": 0.8172455430030823}
{"content": "Turmeric Salve Fusion\nThe aromatic root of the turmeric plant has been used for centuries as a treatment for digestive disorders, inflammation, arthritis and infection. Many of turmeric's historic uses are not necessarily supported by scientific evidence. Nevertheless, turmeric supplements are commonly prescribed as a component of modern integrative medicine. According to the University of Maryland Medical Center, early studies suggest that turmeric can promote the health of your joints, blood vessels and digestive tract. Compounds in turmeric capsules may also offer hope as a complementary cancer treatment.", "pred_label": "__label__POS", "pred_score_pos": 0.6761934757232666}
{"content": "Clinically proven to deeply rehydrate the skin by increasing its ability to hold onto water for longer.\nSuper Drink contains 6 potent actives that boost hydration, therefore, reinforcing the skin’s physical integrity, giving it plump fullness. This powerful and natural formula contains essential actives that will help prevent transepidermal water loss and restore deep hydration, leaving the skin feeling smooth, healthy and bouncy.\nSuitable for all skin types with deficiencies causing dehydration, dryness, thinning skin and fine lines.\n20ml\nBenefits\nSuper Actives are potent clinically proven plant-powered ingredients which have been encapsulated into a unique liposome. Liposomes are like biocompatible bubbles made from the same material as the skin’s cell membrane. These bubbles are filled with Serum Factories unique super active formulas and are delivered into the skin to target specific skin problems.\nEAU DE SOURCE MARINE 80%: this water is rich in minerals and trace elements and stimulates lipid synthesis to reinforce the skin's barrier function and prevent water loss. It enhances cohesion between the dermis and the epidermis by increasing the number of hemidesmosomes which are mini spring-like structures that give the skin fullness and bounce.\nMARIMOIST: proven to function as a water \"attractor\" and an excellent delivery system for water to the skin.\nHYALURONIC ACID: can attract 1000 times its weight in water.\nPENTAVITIN: long-lasting barrier repair features for long-term hydration, increasing the skin's moisture reservoir for 72 hours.\nFUCOCERT: relieves the spread of inflammation and allergic reactions, increases hydration by 44% one hour after application.\nLACTIC ACID: derived from fruits, this alpha hydroxy acid strengthens the acid mantle to balance healthy hydration levels.\nHow to Use\nShake serum before use. Apply 3-4 drops to a clean face in the morning and at night. Super Drink can be used alongside any serum, cream or oil for extra hydration. Always layer products on the skin from lightest to heaviest.\nFormulated Without\nAnimal products, gluten, silicone, drying alcohols, SLS, parabens, phthalates, PEGs, ethanolamines, chemical sunscreens, synthetic fragrance, BHT, and BHA.", "pred_label": "__label__POS", "pred_score_pos": 0.5764867663383484}
{"content": "Having a beautiful home is great, but maintaining a front yard all year round can be costly. We’ve pulled together some front yard landscaping ideas (budget-friendly options included) to help you maintain the exterior appearance of your home.\nA backyard can be many things. A place for entertaining, another home within the same vicinity of your beloved home, a haven for rest and relaxation, or an area for sport and activities.\nRegardless of the many ways you may use your backyard, maximizing your space on a budget can often be a challenge.\nEven if you were to hire a trusted landscaping service, you may not even know what backyard design to begin with. This is why we’ve decided to share with you the most common ideas we discuss during a one-on-one backyard landscaping design consultation.\nThe 59 Best Landscaping Blogs, Influencers, Instagram Accounts, Historical Sites, Magazines & Websites Landscaping Tips For Sandy Springs' Homeowners Authors\nWe love everything landscaping. We don't love writing too much, but we are giving it a go! We hope y'all enjoy it.", "pred_label": "__label__POS", "pred_score_pos": 0.5151828527450562}
{"content": "Our bankruptcy compliance and consumer bankruptcy litigation attorneys provide our clients’ bankruptcy departments with practical guidance both in and out of court. The team has decades of experience in consumer bankruptcy litigation and manages our clients’ caseloads efficiently and effectively.\nThe team also has leveraged prior matters to predict ranges of outcomes and contain legal costs. We apply that litigation experience – together with our experience guiding clients through a broad range of enforcement, remediation, and audit engagements – to provide practical regulatory and compliance advice and help our clients enhance the efficiency of their bankruptcy compliance management systems.\nBradley’s compliance and regulatory lawyers partner with in-house legal departments, default servicing management and operational staff at financial institutions helping them navigate the current bankruptcy regulatory environment. Our team includes lawyers that have served extended periods as temporary in-house bankruptcy counsel to various clients, including a Fortune 100 financial institution and one of the nation’s leading mortgage servicers.\nAdditionally, nearly all the members of our team have spent significant time on-site with our financial services clients, fully immersed in their bankruptcy departments and systems of record, working closely with key bankruptcy personnel to address the wide-ranging issues facing bankruptcy departments.\nAs trusted legal counsel, we bring our deep experience and informed perspective to helping clients avoid potential statutory or regulatory violations by addressing bankruptcy compliance and consumer financial protection issues proactively while keeping in mind the limitations on our clients’ financial, human, and IT resources. Our preventive measures eliminate or minimize litigation, financial repercussions, and other disruptions to our clients’ businesses.\nTo ensure compliance with the Bankruptcy Code provisions, Bankruptcy Rules, local rules, administrative orders, and servicing standards established by federal and state regulators, Bradley attorneys:\nOur consumer bankruptcy litigation team represents financial services clients in numerous states, effectively containing their legal spend by guiding them through potential outcomes and helping them choose their battles wisely under the specific circumstances of each case. We understand the desire to resolve matters quickly when appropriate.\nThrough our deep bankruptcy experience and grasp of the relevant facts in each case, we often are able to negotiate early resolutions with opposing counsel. When an early resolution is not feasible, we zealously represent our clients’ positions before the bankruptcy court while containing costs as much as possible.\nMatters we handle include:", "pred_label": "__label__POS", "pred_score_pos": 0.9559870958328247}
{"content": "A living will is a legal document that allows patients to provide healthcare providers with an outline of their wishes in the event they become incapacitated and unable to communicate their wishes themselves. The document often contains a provision for a person to be designated as healthcare power of attorney. This individual can speak on the patient’s behalf if he or she cannot do so.\nKentucky has specific living will laws as outlined in the Kentucky Living Will Directive Act. These are some of the highlights of this important law.\nIn Kentucky, a valid living will must have four components:\nLiving wills are revocable in the same way that traditional wills are. Methods of revocation include:\nRevocation is effective immediately. This action overrides any previous written healthcare directives.\nIt’s worth noting that healthcare providers may follow living wills or advance directives created outside of Kentucky, so long as those directives are consistent with generally accepted medical practices. If a doctor cannot follow the instructions of the living will, he or she must inform the patient and the family, and cannot impede transferring the patient to a healthcare facility or doctor who can comply with the instructions.", "pred_label": "__label__POS", "pred_score_pos": 0.9982982873916626}
{"content": "Northern Beaches naturopathy belief is not to nurse symptoms but to treat the cause of imbalance.\n$60.00\nOmega Max fish oil\nHighly concentrated dose of omega-3 polyunsaturated fatty acids. Each softgel contains: 650mg of eicosapentaenoic acid (EPA) and 400mg of docosahexaenoic acid (DHA).\nComplies with the strictest quality standards set for acceptable levels for common contaminants including lead, cadmium, mercury, arsenic, dioxins and polychlorinated biphenyls (PCBs).\nSourced from small fish like Sardines, Anchovies and Whitebaits\nEssential fatty acids, in the correct ratio, play a critical role in a wide variety of health related conditions.Recognising the roles that fish oils have in structure and physiologic functioning is a necessary step towards re-establishing EFA levels and ratios in the body.Used at the recommended dose EFAs are safe and devoid of toxicity but caution is required with high doses in patients scheduled for surgery and those currently on anticoagulant therapy.\nDIRECTIONS\nAdults: Take 1 softgel once daily or as directed by your healthcare", "pred_label": "__label__POS", "pred_score_pos": 0.5350133776664734}
{"content": "Importance of the Resilient Kids Boot Camp Game\nThe reality of life is that all human beings get stressed more often than they realize. Learning how to navigate through challenging events and manage stress is not easy. Over exposure to stress in children has been found to cause decreased academic performance, problems with attention, impulsive behaviors, increased depression and anxiety, sleep problems, and social struggles However, the ability to be remain calm during difficult events and utilize healthy coping skills to manage stress is a skill set that can be taught and developed.\nCreative Ways To Use The Game\n*Via teletherapy-For example, the cards can be \"fanned\" across the screen allowing the child to select a card. Discussion and problem solving to follow. Game board is used with family in between sessions to reinforce skills.\n*In person\n*With individuals or groups\n*At home during family game time\n*One skill card a day as a journal topic\n*Role play\n*Classroom guidance\nReasons To Play\n*To help children build resiliency as they develop mindfulness and social skills, as well as learn how to regulate emotions and handle stress.\n*Resilience training and practice will assist children find meaning in stressful events and learn how to stay present focused.\n*Teach children a skill set to remain calm when placed into challenging events or situations.\nDisclaimer: Please note that while playing this game may enhance coping skills, individual results and outcomes may vary.", "pred_label": "__label__POS", "pred_score_pos": 0.941586434841156}
{"content": "Latin Name: Origanum marjorana Country: Hungary Method: steam distilled Status:\nconventional\nDescription: Marjoram is a heady essential oil, with a deep, warming spice that is surrounded by a mild sweetness, and is most noted for its potent sedating effects.\nIt is useful for clearing bruises, healing minor wounds, and reducing toothaches. It has been shown to be beneficial when treating bronchitis, breathing difficulties, respiratory distress & infections, snoring, headaches, migraines, arthritis, muscle aches & stiffness, muscle spasms, sprains, rheumatism, irregular heartbeat, constipation, flatulence, digestive infections & complaints, and ulcers.\nMarjoram is also known for assisting in regulating menstrual cycles, providing relief from painful periods, as well as tension, moodiness, and anxiety associated with PMS. It is considered an anaphrodisiac (curbs excessive sexual appetite) and may also assist in the removal (or repelling) of ticks.\nThis essential oil is excellent for tackling strong emotions and hindering fears. It is commonly used to address high stress issues, nervous tension, impatience, grief, panic, psychosis (to an extent), and sharp sadness. It may be used to combat feelings of claustrophobia, oppression, and irritability. It has been used to assist in the release of obsessions, and sometimes helps to relieve deep trauma.\nThe subtle (energetic) properties of Marjoram don't stray too far from its core psychological benefits. Said to allow individuals to embrace their unconscious fears, it allows one to step away from fears with comfort and support. It's a powerful tool for individuals suffering from grief, as it will assist in acceptance of deep, emotional loss. Marjoram is said to increase the attraction of love, happiness, health, and wealth, as well as promote our ability to give. It may be useful for those attempting a period of celibacy (particularly after a break up), and may help us to forgive without judgment or criticism, for no other reason than to have an untroubled heart.\nContraindications: Not recommended for use during the 1st trimester of pregnancy. Use caution around those with asthma, low blood pressure, and acute depression. It has been suggested that prolonged overuse may deaden the emotions, though regular proper use should not have this effect.", "pred_label": "__label__POS", "pred_score_pos": 0.6875346899032593}
{"content": "Περίληψη : The present dissertation explores the existence of offsetting movements between private and public saving, in a global level, for the period 1970-2015. The study of saving behavior aims to provide evidence in favor of Ricardian Equivalence or against it. Ricardian Equivalence is a proposition, initially formulated by David Ricardo and since then it has divided the economists. The proposition suggests that, under some assumptions, an individual should be indifferent about how a government will finance its spending (by taxation or debt issuing). A detailed literature review is presented, while the main hypothesis is tested with dynamic panel data econometric methods. The empirical results provide support forthe existence of partial Ricardian behavior but reject the hypothesis of pure Ricardian Equivalence. We also discuss the factors that make the existence and the examination of Ricardian Equivalence a complicated procedure.", "pred_label": "__label__POS", "pred_score_pos": 0.7267642021179199}
{"content": "DOI:10.1128/jb.177.14.4131-4133.1995 ABSTRACT\nWe have studied the response of Vibrio vulnificus to temperature shifts (23 to 13 degrees C) within the organism's permissive growth range. Cold shift induced a diminution in protein synthesis. Following a short lag, cells began growth at a new rate. Forty proteins were induced by this downshift.", "pred_label": "__label__POS", "pred_score_pos": 0.7055384516716003}
{"content": "Genetic changes involved in the metaplastic progression from squamous esophageal mucosa toward Barrett's metaplasia and adenocarcinoma are almost unknown. Several evidences suggest that some miRNAs are differentially expressed in Barrett's esophagus (BE) and esophageal adenocarcinoma. Among these, miR-143, miR-145, miR-194, miR-203, miR-205, miR-215 appear to have a key role in metaplasia and neoplastic progression. The aim of this study was to analyze deregulated miRNAs in serum and esophageal mucosal tissue biopsies to identify new biomarkers that could be associated with different stages of esophageal disease. Esophageal mucosal tissue biopsies and blood samples were collected and analyzed for BE diagnosis. Quantitative Real-time PCR was used to compare miRNA expression levels in serum and 60 disease/ normal-paired tissues from 30 patients diagnosed with esophagitis, columnar-lined oesophagus (CLO) or BE. MiRNA expression analysis showed that miR-143, miR-145, miR-194 and miR-215 levels were significantly higher, while miR-203 and miR-205 were lower in BE tissues compared with their corresponding normal tissues. Esophageal mucosa analysis of patients with CLO and esophagitis showed that these miRNAs were similarly deregulated but to a lesser extent keeping the same trend and CLO appeared as intermediate step between esophagitis and BE. Analysis on circulating miRNA levels confirmed that miR-194 and miR-215 were significantly upregulated in both BE and CLO compared to esophagitis, while miR-143 was significantly upregulated only in the Barrett group. These findings suggest that miRNAs may be involved in neoplastic/ metaplastic progression and miRNA analysis might be useful for progression risk prediction as well as for monitoring of BE/CLO patients.\nLingua originale English pagine (da-a) 47821-47830 Numero di pagine 10 Rivista Oncotarget Volume 7 Stato di pubblicazione Published - 2016", "pred_label": "__label__POS", "pred_score_pos": 0.7626704573631287}
{"content": "Recent PhD graduate Lawrence Williams has published an article in\nFrontiers in Sociology entitled, “How Career Identity Shapes the Meaning of Work for Referred Employees.” The article dismantles previous sociological explanations surrounding the phenomenon of referred employees having longer tenures than non-referred employees. Within the study, the author demonstrates how career plans or career identity shaped how information and peer support led to respondents either staying in or leaving their jobs.\nLawrence Williams recently defended his dissertation in the Department of Sociology at the University of Toronto. His research interests lie within sociological theory, sociology of culture, and deviance. His current research focuses on how individuals working in the field of customer service understand their careers and find meaning at work. It also examines the role of intuition in major life decisions.\nWe have posted the citation and the abstract below. The full text is available through\nFrontiers in Sociology, here.\nWilliams, Lawrence H. 2019. “How Career Identity Shapes the Meaning of Work for Referred Employees.”\nFrontiers in Sociology 3.\nSociological explanations for why referred employees typically have longer tenures than non-referred employees tend to be either that referred employees enter their jobs possessing a clearer sense of employer expectations or that they often receive support from their referrers while on the job. However, through analysis of work-history interviews conducted with salespersons in Toronto, Canada, I find that the significance of each of these factors for a person’s tenure depends on their career plans. For individuals with clear career plans, information mattered but support was less important. Conversely, for individuals with unclear career plans, support mattered but information was less important. I find that this divergence was based on the fact that individuals who had clearer career plans cared more about the fit they had with the\ntasksthey performed in jobs which they were referred into while those with unclear plans tended to be more concerned about their overall fit with the job’s culture. I examine this difference in job satisfaction by demonstrating how the combination of information and support respondents had at any given job led them to either support, interrogate, or re-route their career plans differently based on the initial clarity of these plans. Based on these findings, I argue that the role that referrals play in shaping turnover intentions should be nested within individuals’ career identities. Doing so prevents researchers from seeing turnover intentions as being solely based on expectations at the time of hire or on connections made, strengthened, or weakened on-the-job and, instead, necessitates a more grounded view of turnover decisions.", "pred_label": "__label__POS", "pred_score_pos": 0.9188332557678223}
{"content": "Defining a formal sales methodology helps the sales organization realize repeatable and scalable results by replicating the behaviors and activities of high performers. However, companies often adopt a new sales methodology with little understanding of what they are getting and what it will take to ensure a successful implementation and ongoing engagement. This session will explore the various types of sales methodologies, the business needs that a methodology addresses, and a process for internal discovery, methodology definition and alignment to sales outcomes.\nThis session will provide the following benefits:", "pred_label": "__label__POS", "pred_score_pos": 0.9966604113578796}
{"content": "Successful real estate developers and development attorneys must effectively anticipate and manage risk. Managing visible and known risks seems simple; what separates the great from the good is the ability to anticipate, plan for, and develop contingencies for unknown risk scenarios. Failure to account for these risks can be catastrophic. Hurricanes Harvey and Katrina unveiled the stark consequences of the failure to adequately plan for catastrophic events, showcasing chemical-plant explosions, flooded buildings, and lost real estate assets. Extreme weather conditions are increasing in severity and frequency, and oceans are rising, so resilient real estate developers must adapt and engineer buildings and site configurations that are sustainable under changing climatic conditions.\nPremium Content For: Environment, Energy, and Resources Section", "pred_label": "__label__POS", "pred_score_pos": 0.550324559211731}
{"content": "CTS are your trusted provider of Commercial Intruder, Fire, CCTV and Access Control Systems\nAs a business, you have duty to ensure that your staff and anyone visiting your premises are safe and secure. This can be achieved by having a professionally installed and maintained security system, which will include Intruder Alarm, Fire, CCTV and Access Control Systems. These systems protect both property and people.\nAdditionally, you may benefit from lower insurance premiums if your business is adequately protected from burglary and fire.\nYou should choose a reputable installer that can provide you with a security system that is certified and installed to the latest industry standards, and who can prove their credentials to you.\nAs an NSI Gold approved company employing only the best staff, which includes vetted and highly skilled security system engineers, you can rest assured that we will design and install a security system for you, to the highest standards, using the most up to date equipment and technology.\nWe are proud to have worked with many commercial clients across East Anglia and further afield, from small shops to international companies occupying large commercial premises in the UK. We are confident that our clients would vouch for our excellent standards of service, both before, during and after installation.", "pred_label": "__label__POS", "pred_score_pos": 0.6018619537353516}
{"content": "Unless your plan terms provide otherwise, the salary (elective) deferral limit is applied uniformly to the compensation that the employee receives throughout the year. Compensation and contribution limits are subject to annual cost-of-living adjustments. The annual limits are: salary deferrals - $19,500 in 2020 and 2021 ($19,000 in 2019), plus $6,500 in 2020 and 2021 ($6,000 in 2015 - 2019) if the employee is age 50 or older (IRC Sections 402(g) and 414(v)) annual compensation - $290,000 in 2021, $285,000 in 2020, $280,000 in 2019 (IRC Section 401(a)(17)) total employee and employer contributions (including forfeitures) - the lesser of 100% of an employee’s compensation or $58,000 for 2021 ($57,000 for 2020 not including \"catch-up\" elective deferrals of $6,500 in 2020 and 2021 ($6,000 in 2015 - 2019) for employees age 50 or older) (IRC section 415(c)) Example: Mary, age 49, whose annual compensation is $360,000 ($30,000 per month), elects to defer $1,500 per calendar month, up to $19,000 for the 2019 year. Mary may contribute to the plan until she reaches her annual deferral limit of $19,000 even though her compensation will exceed the annual limit of $280,000 in October. Employer matching contributions If your plan provides for matching contributions, you must follow the plan’s match formula. Example: Your plan requires a match of 50% on salary deferrals that do not exceed 5% of compensation. Although Mary earned $360,000, your plan can only use up to $280,000 of her compensation when applying the matching formula for 2019. Mary’s matching contribution would be $7,000 (50% x (5% x $280,000)). Although Mary makes salary deferrals of $19,000, only $14,000 (5% of $280,000) will be matched. She must receive a matching contribution of $7,000 (50% x $14,000) under the terms of the plan. What does your plan say? Although not common, a plan can specifically require that salary deferrals cease once a participant’s compensation reaches the annual limit. If your plan specifies that salary deferrals be based on a participant’s first $280,000 of compensation, then you must stop allowing Mary to make salary deferrals when her year-to-date compensation reaches $280,000, even though she hasn’t reached the annual $19,000 limit on salary deferrals, and must base the employer match on her actual deferrals. Additional resources Retirement Topics – Contributions FAQs: Contributions Publication 560, Retirement Plans for Small Business (SEP, SIMPLE, and Qualified Plans)", "pred_label": "__label__POS", "pred_score_pos": 0.5195465087890625}
{"content": "Predicting cognitive resilience from midlife lifestyle and multi-modal MRI: A 30-year prospective cohort study. Topiwala A., Suri S., Allan C., Valkanova V., Filippini N., Sexton CE., Heise V., Zsoldos E., Mahmood A., Singh-Manoux A., Mackay CE., Kivimäki M., Ebmeier KP.\nBACKGROUND: There is significant heterogeneity in the clinical expression of structural brain abnormalities, including Alzheimer's disease biomarkers. Some individuals preserve their memory despite the presence of risk factors or pathological brain changes, indicating resilience. We aimed to test whether resilient individuals could be distinguished from those who develop cognitive impairment, using sociodemographic variables and neuroimaging. METHODS: We included 550 older adults participating in the Whitehall II study with longitudinal data, cognitive test results, and multi-modal MRI. Hippocampal atrophy was defined as Scheltens Scores >0. Resilient individuals (n = 184) were defined by high cognitive performance despite hippocampal atrophy (HA). Non-resilient participants (n = 133) were defined by low cognitive performance (≥1.5 standard deviations (S.D.) below the group mean) in the presence of HA. Dynamic and static exposures were evaluated for their ability to predict later resilience status using multivariable logistic regression. In a brain-wide analysis we tested for group differences in the integrity of white matter (structural connectivity) and resting-state networks (functional connectivity). FINDINGS: Younger age (OR: 0.87, 95% CI: 0.83 to 0.92, p<0.001), higher premorbid FSIQ (OR: 1.06, 95% CI: 1.03 to 1.10, p<0.0001) and social class (OR 1 vs. 3: 4.99, 95% CI: 1.30 to 19.16, p = 0.02, OR 2 vs. 3: 8.43, 95% CI: 1.80 to 39.45, p = 0.007) were independently associated with resilience. Resilient individuals could be differentiated from non-resilient participants by higher fractional anisotropy (FA), and less association between anterior and posterior resting state networks. Higher FA had a significantly more positive effect on cognitive performance in participants with HA, compared to those without. CONCLUSIONS: Resilient individuals could be distinguished from those who developed impairments on the basis of sociodemographic characteristics, brain structural and functional connectivity, but not midlife lifestyles. There was a synergistic deleterious effect of hippocampal atrophy and poor white matter integrity on cognitive performance. Exploiting and supporting neural correlates of resilience could offer a fresh approach to postpone or avoid the appearance of clinical symptoms.", "pred_label": "__label__POS", "pred_score_pos": 0.9920495748519897}
{"content": "Victims of Lawsuit Claim Support in a case against Xarelto. Doctors claim that it had unlisted and daunting side effects.\nDrs. John C. Hwang and Judy Hun observed patients from their practice who were currently participating in a long-term blood thinner regimen and ranged in age from 70 to 89. While they were originally taking more traditional medications, they switched to Xarelto after its FDA approval in 2011. According to empirical observation, these patients showed a marked increase in incidents of vitreous hemorrhages or eye-bleeding that appeared to coincide with their change in medication. Victims of Lawsuit Claim Support after receiving side effects. The doctors noted that the bleeding events were most likely to occur in those who had an established history of blood thinner use, such as warfarin, and switched to the new-generation anticoagulant. Hwang and Hun published their complete findings in the June 2015 issue of JAMA Ophthalmology, and noted, “In all cases, an acute vitreous hemorrhage occurred shortly after rivaroxaban (Xarelto) treatment was initiated.” Another landmark study was published in the April 2015 issue of the British Medical Journal (BMJ) that indicated as high as a two-fold increase in the risk for stomach bleeds by patients taking Xarelto in lieu of warfarin. For the purposes of the study, investigators screened nearly 46,000 complete medical histories. It was noted that the bleeding events were most common in those who had been taking warfarin, but weaned off the drug in favor of the promising new treatment option presented by Xarelto. In the United States, more than 2,800 individual cases against Xarelto and its manufacturers have been consolidated to form the multidistrict litigation (MDL) No. 2592. The common allegations of the plaintiffs in these cases include a substantially increased risk of catastrophic bleeding events, injury, and even death. Judge Eldon Fallon has been appointed to oversee the MDL proceedings in the Eastern District Court of Louisiana.\nOriginally Posted by Laurence Banville of the Legal Examiner Victims of Lawsuit Claim Support – Ball and Bonholtzer Trail attorney – Los Angeles", "pred_label": "__label__POS", "pred_score_pos": 0.9307593107223511}
{"content": "Hypertrophy, hyperplasia and altered mucus secretion from the respiratory submucosal glands (SMG) are characteristics of airway diseases such as cystic\nfibrosis, asthma and chronic bronchitis. More commonly, hyper-secretion of the nasal SMGs contributes to allergic rhinitis and upper airway infection. Considering the role of these glands in disease states, there is a significant dearth in understanding the molecular signals that regulate SMG development and patterning. Due to the imperative role of FGF signalling during the development of other branched structures, we investigated the role of Fgf10 during initiation and branching morphogenesis of murine nasal SMGs. Fgf10 is expressed in the mesenchyme around developing SMGs while expression of its receptor Fgfr2 is seen within glandular epithelial cells. In the Fgf10 null embryo, Steno's gland and the maxillary sinus gland were completely absent while other neighbouring nasal glands showed normal duct elongation but defective branching. Interestingly, the medial nasal glands were present in Fgf10 homozygotes but missing in Fgfr2b mutants, with expression of Fgf7 specifically expressed around these developing glands, indicating that Fgf7 might compensate for loss of Fgf10 in this group of glands. Intriguingly the lateral nasal glands were only mildly affected by loss of FGF signalling, while these glands were missing in Eda mutant mice, where the Steno's and maxillary sinus gland developed as normal. This analysis reveals that regulation of nasal gland development is complex with different subsets of glands being regulated by different signalling pathways. This analysis helps shed light on the nasal gland defects observed in patients with hypohidrotic ectodermal dysplasia (HED) (defect EDA pathway) and LADD syndrome (defect FGFR2b pathway). Submucosal gland (SMGs), FGF10, EDA, branching morphogenesis\nID: 27620637", "pred_label": "__label__POS", "pred_score_pos": 0.8155978918075562}
{"content": "Download as Adobe PDF\nFinal published version, 6.12 MB, PDF document\nLicence: Creative Commons: Attribution (CC-BY)\nAgeing has a profound effect on the immune system, termed immunosenescence, resulting in increased incidence and severity of infections and decreased efficacy of vaccinations. We previously showed that immunosurveillance in the intestine, achieved primarily through antigen sampling M cells in the follicle associated epithelium (FAE) of Peyer’s patches, was compromised during ageing due to a decline in M cell functional maturation. The intestinal microbiota also changes significantly with age, but whether this affects M cell maturation was not known. We show that housing of aged mice on used bedding from young mice, or treatment with bacterial flagellin, were each sufficient to enhance the functional maturation of M cells in Peyer’s\npatches. An understanding of the mechanisms underlying the influence of the intestinal microbiota on M cells has the potential to lead to new methods to enhance he efficacy of oral vaccination in aged individuals M cells, Peyer’s patches, small intestine, mucosal immunity, ageing, microbiota, flagellin, IgA\nID: 146469646", "pred_label": "__label__POS", "pred_score_pos": 0.9510889053344727}
{"content": "Abstract\nPublished evidence indicates that nearly 60% of blueberry-producing countries experience yield instability. Yield is a complex trait determined by genetic and environmental factors. Here, using physiological and biochemical approaches, we tested the hypothesis that yield instability results from year-to-year environmental variation that limits carbon assimilation, storage and partitioning. The data indicate that fruit development depends primarily on the daily production of non-structural carbohydrates by leaves, and there is no accumulation of a starch buffer to allow continuous ripening under conditions limiting for photosynthesis. Photosynthesis was saturated at moderate light irradiance and this was mainly due to stomatal and biochemical limitations. In a dynamic light environment, photosynthesis was further limited by slow stomatal response to increasing light. Finally, labelling with 13 CO 2 at specific stages of fruit development revealed a relatively even distribution of newly assimilated carbon between stems, roots and fruits, suggesting that the fruit is not a strong sink. We conclude that a significant component of yield variability results from limitations in photosynthetic efficiency that are compounded by an inability to accumulate starch reserves in blueberry storage tissues in a typical northern European environment. This work informs techniques for improving agronomic management and indicates key traits required for yield stability in such environments.\nKeywords 13 CO 2 -labelling Vaccinium carbon assimilation carbon storage corymbosum sink tissues starch yield", "pred_label": "__label__POS", "pred_score_pos": 0.9894106388092041}
{"content": "The STAT3 Signaling Pathway affects Sca1+ Bone-associated Progenitors in the Hematopoetic Stem Cell Niche Author: Michael Wong Mentors: Xingbin Hu, Postdoctoral Fellow, City of Hope Ching-Cheng Chen, Principal Investigator, City of Hope\nThe hematopoetic niche is the core regulation machinery for hematopoietic stem cell (HSC) differentiation and self-renewal in bone marrow. STAT3 is a highly conserved signaling pathway that is involved in cell proliferation and cell cycle, but it is not yet known whether the STAT3 signal is a definite player in niche constitution. We previously confirmed that Sca1+ bone associated progenitors can differentiate into stroma lineages to maintain HSCs. This study aims to functionally characterize the role of the STAT3 signal on Sca1+ cells and their function in the hematopoetic niche. A transgenic osteotrix:STAT3 knockout mouse model was used for analysis. By flow cytometry, Sca1+ populations were isolated and examined. It was observed that STAT3 knockout populations exhibited increased myeloid lineages in peripheral blood and spleen samples. The myeloid lineage changes are believed to be a result of the Sca1+ bone associated progenitors because, firstly, the osteotrix:STAT3 knockout mice exhibited significantly increased Sca1+ sub-populations, and secondly, the down-regulated STAT3 Sca1+ cells co-cultured long-term improved the HSCs' engraftment in bone marrow transplantation assays. It was also observed in vitro that down-regulated STAT3 Sca1+ cells’ proliferation also rose. This observation is consistent with the earlier findings that Sca1+ populations increase when STAT3 is down-regulated or knocked out. This study is significant in clarifying how the STAT3 pathway participates in the niche constitution, a key component in HSC maintenance.\nPresented by: Michael Wong Date: Saturday, November 17, 2012 Time: 3:45 PM — 4:00 PM Room: Bell Tower 2515 Presentation Type: Oral Presentation Discipline: Biology", "pred_label": "__label__POS", "pred_score_pos": 0.7761561274528503}
{"content": "This focus report provides a summary of States’ Social Services Block Grant (SSBG) expenditures for, and recipients of, support services for older adults across all SSBG service categories. The SSBG program defines older adults as individuals 60 years of age and older. An analysis of 6-year trends in the use of SSBG expenditures for these services is also included.", "pred_label": "__label__POS", "pred_score_pos": 0.7189581394195557}
{"content": "Interested in becoming a foster carer, but want to know more about if you can foster? Perhaps you’re a single parent, or you’re currently renting a property and wondering if this affects your application? Our detailed guide breaks down fostering requirements, as well as addressing some myths and misconceptions around who can become a foster carer.\nIn order to become a foster carer, as a first port of call, there are three primary fostering requirements you need to have:\nHowever, there are other requirements that you’ll need to become a foster carer – such as a home where children under five are placed should be non-smoking, and your home should not have any aggressive pets or dangerous pets. Often with fostering, there are many misconceptions regarding whether you can foster based on your career, experience or living situation. That’s why we put together our top 10 fostering myths guide which highlights the most common misconceptions about who can foster.\nWhether you apply through your local authority or through an independent fostering agency, such as Capstone Foster Care, during the application process, you will undergo a health check and all members of your household over the age of 18 will undergo a Disclosure and Barring (DBS) check. Foster care training, help and support are provided during the application process and throughout your fostering work.\nIf you have any questions regarding who can foster, or wondering ‘Can I foster if…?’, our detailed guide can help. Alternatively, get in touch with a member of our expert team here at Capstone Foster Care.\nYou can chat with us online and you can get the answers to your questions immediately.", "pred_label": "__label__POS", "pred_score_pos": 0.6039493083953857}
{"content": "13,000 people are injured each year from ordinary objects that are unsecured in car accidents. It is vital that items in your car are secured safely and properly. At the moment of impact a seemingly innocuous item can be propelled to lethal speeds.\n“Sometimes the most dangerous things we face in an accident can come from inside the car” Practice safe cargo securing\nIt is our recommendation/belief that all our items are stowed securely in the car.\n-Place large items in the car trunk and fasten them securely\n-Smaller items such as phones should be placed in compartments or even in your pocket\n-Water bottles should be placed securely into their holders\n-Briefcases and purses should be placed in the car trunk\n-Ideally heavy items should be placed up against the rear of the passenger seat in the trunk\n-Straps and tie downs should be used where possible\n-Small and pointy objects should be placed in boxes away from passengers\n-Pets should be in secured carriers at all times\nThe below German crash test videos demonstrate how dangerous unsecured luggage can be.", "pred_label": "__label__POS", "pred_score_pos": 0.8261327743530273}
{"content": "- Discussion:\n- deformity is characterized by severe angular deformity with a prominent gibbus at the apex of the curve;\n- etiology involves either failure of\nsegmentationor defect in formationof vertebral body elements;\n-\ndefect of formation:\n- failure of formation of the anterior elements produces the worst deformity;\n- prognosis for defect in formation is considerably worse;\n- natural history involves relentless progression of deformity;\n-\nsequelae:\n-\nparaplegiacommonly results if untreated;\n- breakdown of the overlying soft tissues;\n- compression of the abdominal viscera;\n- impairment of pulmonary function;\n- poor sitting posture;\n-\ndefect of segmentation:\n- slightly better prognosis;\n- produces a more rounded kyphotic shape;\n- deformity progresses more slowly and paraplegia is uncommon;\n- Posterior Fusion: - in children < 5 yrs w/ curves < 55 deg, only an situ posterior arthrodesis is required since some spontaneous correction of kyphosis will occur with continued growth; - posterior fusion may have wider indications w/ kyphosis due to failure of segmentation (as opposed to failure of formation); - posterior kyphectomy & arthrodesis involve meticulous care of tissues; - resection of the non-functioning cord at apex of the deformity; - water-tight dural closure, w/ care being taken not to occlude terminal end of normal spinal cord at site of transection of cord; - bivalve total-contact orthosis is used to support trunk until fusion is solid; - Anterior & Posterior Fusion: - combined anterior & posterior fusion is indicated for children > 5 years, and curves > 55 deg; - paralytic deformity: - reconstruction begins w/ anterior release w/ interbody arthrodesis; - decompression of spinal cord anteriorly is required;; - as a staged procedure, posterior arthrodesis is followed by segmental spinal fixation to pelvis; - reduction: - correction of kyphotic defomrity carries a high risk of paraplegia, esp when it is tried preoperatively w/ traction; - this will stretch cord over fixed kyphotic deformity; - congenital kyphosis may be corrected intraoperatively if intra operative cord monitoring if available; - anterior arthrodesis: - requires strut graft as well as interbody arthrodesis; - anterior unsegmented bar will develop in growing child if interbody arthrodesis is not added to procedure since unfused vertebral bodies will continue to grow & contribute to the deformity; - strut graft is placed as close to vertebral bodies as possible to reduce the risk of pseudoarthrosis; - vertebral resection: - w/ severe deformity present at birth, vertebral resection and a short arthrodesis may be required for closure of overlying soft tissues; - loss of correction with growth is common, and arthrodesis of entire spine may be required by age 10 yrs\nCongenital kyphosis due to defects of anterior segmentation.", "pred_label": "__label__POS", "pred_score_pos": 0.982305645942688}
{"content": "Vision dominates audition in adults but not children: a meta-analysis of the Colavita effect\nHirst, Rebecca J. and Cragg, Lucy and Allen, Harriet A. (2018)\nAbstract\nThe Colavita effect occurs when participants respond only to the visual element of an audio-visual stimulus. This visual dominance effect is proposed to arise from asymmetric facilitation and inhibition between modalities. It has also been proposed that, unlike adults, children appear predisposed to auditory information. We provide the first quantitative synthesis of studies exploring the Colavita effect, combining data from 70 experiments across 14 studies. A mixed-meta-regression model was applied to assess whether the Colavita effect is influenced by methodological factors and age group tested. Studies reporting response time data were used to test for the presence of asymmetrical facilitation between modalities. Studies with adult participants yielded a medium, approaching large, effect size. Studies exploring the Colavita effect in children yielded no Colavita effect. Across adult and child studies, no methodological factors influenced the effect. Contrary to asymmetrical facilitation, response time data suggested a general slowing under bimodal conditions. These findings suggest that whilst vision dominates in adults, this effect is absent in childhood.\nActions (Archive Staff Only)", "pred_label": "__label__POS", "pred_score_pos": 0.7793923616409302}
{"content": "The proliferation of molecular diagnostics is bringing a tidal wave of complexity, cost and quality issues for payers, clinicians and laboratories. As a result, payers are accelerating efforts to appropriately manage (Read the full article)\nLab Processes and Procedures\nMedical laboratories are a critical part of the healthcare system. A patient’s diagnosis and treatment are often based on test results, and an incorrect laboratory test result could lead to (Read the full article)", "pred_label": "__label__POS", "pred_score_pos": 0.9852434396743774}
{"content": "Jackie Burke’s presentation that focused on the challenges for trauma exposed workforces. It explores the multiple meanings of ‘complex trauma’ and the implications for women’s wellbeing and safety from violence. Key discussions include:\nThe Challenge of Responding to Multiple Needs in the Right Order The Challenge of Responding Effectively to “Needs in Disguise” The Challenge of Problem Saturated Work The Challenge of Vicarious Traumatisation", "pred_label": "__label__POS", "pred_score_pos": 0.9998641610145569}
{"content": "One of our clients, a leading global automotive supplier with operations across Europe, was struggling with fragmented Finance processes that inhibited performance. Other issues it faced included a high degree of manual intervention, lack of standardization and the expense of maintaining a high percentage of staff in relatively high cost European locations. To align cost levels toward global best practices and drive improved data harmonization, the company opted for a shared services model. Chazey was engaged to develop a business case (see the part one of this series) and subsequently help launch a new, pan-Europe shared services center.\nThis article explores how the company implemented the end-to-end rollout of its Finance shared services after the pre-launch of the business case development phase. It highlights the Design phase as crucial to successful shared services implementation and share a planning roadmap.\nThe paper forms part of “How to implement a new shared services center” series as part two. Part one explains shared services feasibility study and business case development.", "pred_label": "__label__POS", "pred_score_pos": 0.9996309876441956}
{"content": "The injustices of high- versus low-skilled temporary labour migration programs: With evidence from Canada\nOften, however, these critics fail to distinguish between high- and low-skilled TLMP, the stipulations of which are often quite distinct. Where they do distinguish between them, the common conclusion is that only low-skilled TLMP pose problems of justice which require immediate action. Patti Lenard will examine these assumptions. She argues that both low- and high-skilled TLMP often pose problems of justice, and that while some of these apply only to high- or low-skilled programs, there are others which apply to both. She will illustrate these dilemmas by reference to the Canadian case, where the government has expanded the number of migrants participating in TLMP significantly over the last 10 years.", "pred_label": "__label__POS", "pred_score_pos": 0.9579043984413147}
{"content": "Abstract\nIntracranial subdural hemorrhage is a rare complication of lumbar puncture. Caudal traction and tear of the subdural veins due to negative pressure caused by leakage of cerebrospinal fluid (CSF) following lumbar puncture (LP) is the mechanism. Prolonged headache or neurological symptoms following LP should warrant cross-sectional imaging to rule out subdural hemorrhage as it can be fatal. We report a case of subdural hemorrhage following LP in a patient with suspected meningitis and communicating hydrocephalus.\nKeywords Hydrocephalus Lumbar puncture Meningitis MRI Subdural hemorrhage", "pred_label": "__label__POS", "pred_score_pos": 0.7843950390815735}
{"content": "© 2015 Taylor & Francis. Much academic research on migrant mothers focuses on mothers who are separated from their children, often through their integration into global care chains, or on mothers within the context of family migration. This paper argues that co-resident migrant mothers' experiences provide an important window on the complexities of the migration experience. Using a specific case study of Ireland, and drawing from a broader longitudinal research project that focuses on recent migrants, the paper explores migrant mothers' understandings and experiences of belonging and not-belonging. We argue that structural obstacles and cultural understanding of care actively conspire to undermine migrant mothers' potential to develop place-belongingness. Interviewees' discussions of their status as full-time mothers were often framed through images of ideal motherhood, but equally highlighted how the absence of affordable childcare and family members isolates them and prevents them from creating a sense of belonging outside of the process of mothering and the home.", "pred_label": "__label__POS", "pred_score_pos": 1.0}
{"content": "Estimated reading time: < 1 Minute 20 July 2020\nIn 2017, the UK, Scottish and Welsh Governments agreed they would need to manage policy divergence between the different parts of the UK in some areas covered by EU law.\nThey agreed to establish common frameworks on the basis of set criteria. These criteria included enabling the functioning of the UK internal market, while acknowledging policy divergence; ensuring compliance with international obligations; and ensuring the UK can negotiate, enter into and implement new international agreements, including trade agreements.\nThis briefing summarises developments to early July 2020, considering:\nthe progress of the common frameworks programme; how common frameworks could interact with UK international obligations and the UK internal market; and how law and policy have developed in policy areas where common frameworks are planned, including the development of interim arrangements.\nThis briefing charts the developments that took place before the publication of the UK Government’s\ninternal market white paper. We will publish a second briefing which looks in more detail at the internal market proposals themselves.", "pred_label": "__label__POS", "pred_score_pos": 0.8470556735992432}
{"content": "5. WORKING WITH CARE AND SUPPORT PROVIDERS 5.1 Introduction\nSafeguarding is everyone’s business. This section considers a range of issues about quality and safety, positive practice, safeguarding concerns and managing large scale enquiries. Partnerships between safeguarding and commissioning functions and their interdependent roles and responsibilities towards providers are explored. It is essential to know what works well to support a positive culture of cooperation and information sharing with joint accountability for risk and benefits. It identifies the role and responsibilities of the five groups that influence quality:\nProfessionals and staff Commissioners and funders(Local authorities, CCG and NHS England) Regulators(CQC, Trust Development Agency, Monitor) The public, including adults who use services, their families and carers Providers- A provider for the purposes of this policy and procedure is any care or health provider who delivers support and care to a group of individuals. This would include but is not exclusive to the following: Domiciliary Care Providers Residential Care Homes Nursing Homes Supported Living Private hospitals NHS provision Day Care/Opportunities Providers Rehabilitation Units for people who misuse drugs or alcohol Voluntary agencies Respite provision Hospices\nBy working in partnership these groups can assist early identification if providers are at risk of falling standards that might lead to wider concerns and the need for safeguarding intervention. There is a clear responsibility on commissioners and providers to ensure safe, quality services that will reduce the need for safeguarding interventions.\nThis section is relevant to all providers not just those in the CQC inspection regime. The CQC are responsible for inspecting and monitoring providers registered under the Health and Social Care Act 2008 . It has statutory powers to inspect how well services are performing against ‘Fundamental Standards’ of quality and safety, and can take proportionate enforcement action to ensure providers improve where there is poor care.\nThis section explores work with providers as a means for responding to potential business failure (contracts and commissioning responsibilities) and details how allegations of organisational abuse are managed where safeguarding concerns are identified as serious matters within an organisation as opposed to single concerns that may be addressed under Section 42 (safeguarding responsibilities). Safeguarding concerns in this sense relate to patterns of reported abuse or neglect about one provider, or where a single concern indicates a serious matter that warrants closer inspection under adult safeguarding processes. In some instances, safeguarding action may be initiated following a Safeguarding Adult Review, or run in parallel to one.\nThe focus of this section is on prevention, in particular actions that might be taken in response to concerns about quality issues, to reduce the risk of escalation to safety and safeguarding issues.\nFinally, this section aims to ensure that people have a voice in influencing how services are delivered and where there are concerns, and how their views and experiences lay at the heart of improvements.", "pred_label": "__label__POS", "pred_score_pos": 0.6923888921737671}
{"content": "Recreational outings\nFor five years, Mary lived in Cape Town and regularly took the children out for exciting excursions on the weekends. Now, she commutes to Cape Town once or twice a year for a month at a time. The older children have been on safaris, wilderness reserves and wellness retreats to learn more about their own heritage and art history. These outings give the children invaluable opportunities to encounter new experiences, such as art lessons and exhibitions, exposing them to everyday life and practices that would otherwise have remained unknown to them. Many of the children have never been to a real restaurant before or even used cutlery to eat a meal. In addition to this, good nutrition is also a vital part of maintaining the children’s health, ensuring that their bodies receive the proper sustenance for a good life. These outings show them another side of life, one where every moment is not a struggle, where food and fun are a reality and they can simply relax and enjoy the happy moments.\nWhat the children love most though is when Mary takes them into her own home on weekends. For the past ten years, she has spent countless hours with them, teaching them how to swim and dive, cook and providing the children with general life lessons in a real home environment.\nA Boy’s story\nOn one occasion, Mary and four of the vulnerable children from the townships children’s home, were on a weekend trip to the circus after having spent the morning at her home, bathing and having breakfast. While driving to the circus, a 7-year-old boy looked up from the passenger seat beside her and said “Mary, I don’t want to die.” After a heartbreaking moment, she turned to him and reassured him that if he continued to take his medications and look after himself with healthy food and a careful lifestyle, he could have a long, happy life, with even a wife and children. After hearing this, the little boy squeezed his eyes shut and was quiet for a long while. He then opened his eyes, nodded to himself, and promptly said: “Okay, so how much further to the circus?”", "pred_label": "__label__POS", "pred_score_pos": 0.8375478386878967}
{"content": "A Closer Look at Accommodation Solutions: JAN's Solution Showcase\nWorkplace accommodations for workers with disabilities come in many forms, ranging from the simple to the technical. They can involve digital technology, changes to a workstation, or specialized productivity tools. Regardless, these adjustments to where, when, or how work is done enable qualified individuals with disabilities to perform the essential functions of a job.\nA number of common and effective accommodations are featured in the Job Accommodation Network's (JAN) latest Solution Showcase — a video series highlighting productivity enhancements for workers with a variety of disabilities. Each short video addresses a particular accommodation solution, illustrating the \"why and how\" of the tactic.\nThe newest Solution Showcase videos explore color coding, adjustable workstations, and more. Color coding—which can assist those who face difficulties with organization, prioritization, and memory—can entail using colored post-it notes, paper clips, folders, and binder tabs. The adjustable workstations video showcases sit-and-stand desks and other office and industrial workstations.\nYou can find these new videos on JAN's website, along with all the videos in the helpful series.\nJAN is funded by a contract from the U.S. Department of Labor's Office of Disability Employment Policy.", "pred_label": "__label__POS", "pred_score_pos": 0.9382725954055786}
{"content": "Commercial and residential real estate owners should consider purchasing flood insurance, even if the property is not in a high-risk or flood-prone area. Floods can occur at almost any location from events such as a fast, heavy rainfall; blocked storm drain; or an overflowing stream.\nFlood insurance generally covers your home and its foundation; plumbing and electrical systems; central air and heating systems; cabinets; and a detached garage. Some policies also will cover personal belongings, such as clothing and furniture.\nFlood insurance is typically not included under standard homeowners’, renters’ or commercial property insurance policies.\nFlood insurance is generally purchased through the National Flood Insurance Program, administered through the Federal Emergency Management Agency (FEMA) or private insurers.", "pred_label": "__label__POS", "pred_score_pos": 0.9515588283538818}
{"content": "Thieves may have gotten to the carcass of a sperm whale that recently washed ashore on a Bali beach first, after officials reported all of its teeth missing and pointed to a lack of awareness among the public about the protected specie\nThe twilight zone contains the largest biomass of the world’s ocean. Identifying its role in the trophic supply and contaminant exposure of marine megafauna constitutes a critical challenge in the context of global change. The white shark (Carcharodon carcharias) is a threatened species with some of the highest concentrations of neurotoxin methylmercury (MeHg) among marine top predators. Large white sharks migrate seasonally from coastal habitats, where they primarily forage on pinnipeds, to oceanic offshore habitats. Tagging studies suggest that while offshore, white sharks may forage at depth on mesopelagic species, yet no biochemical evidence exists. Here, we used mercury isotopic composition to assess the dietary origin of MeHg contamination in white sharks from the Northeast Pacific Ocean. We estimated that a minimum of 72% of the MeHg accumulated by white sharks originates from the consumption of mesopelagic prey, while a maximum of 25% derives from pinnipeds. In addition to highlighting the potential of mercury isotopes to decipher the complex ecological cycle of marine predators, our study provides evidence that the twilight zone constitutes a crucial foraging habitat for these large predators, which had been suspected for over a decade. Climate change is predicted to expand the production of mesopelagic MeHg and modify the mesopelagic biomass globally. Considering the pivotal role of the twilight zone is therefore essential to better predict both MeHg exposure and trophic supply to white sharks, and effectively protect these key vulnerable predators.\nOceana regrets that the Fisheries Bill, which has today received Royal Assent making it the Fisheries Act, fails to include a legal duty to fish sustainably, below Maximum Sustainable Yield (MSY), for all stocks. The Fisheries Bill originally offered hope of a new gold standard for fisheries management in the UK, which could have served as an example across the globe. It could\nSharing your scoops to your social media accounts is a must to distribute your curated content. Not only will it drive traffic and leads through your content, but it will help show your expertise with your followers.\nIntegrating your curated content to your website or blog will allow you to increase your website visitors’ engagement, boost SEO and acquire new visitors. By redirecting your social media traffic to your website, Scoop.it will also help you generate more qualified traffic and leads from your curation work.\nDistributing your curated content through a newsletter is a great way to nurture and engage your email subscribers will developing your traffic and visibility.Creating engaging newsletters with your curated content is really easy.", "pred_label": "__label__POS", "pred_score_pos": 0.9790790677070618}
{"content": "In its report ‘The European market for savoury snacks to 2006’ Datamonitor said the UK accounted for almost half of the $4bn European savoury snacks market with consumers spending $28.40 per head in 2001, in return for this they received 3.4 kg of snacks each.\nThe total European market had grown by over $1bn since 1996, representing a 74.5% rise in value, due largely to innovation within this sector and is expected to grow to a value of $5bn by 2006.", "pred_label": "__label__POS", "pred_score_pos": 0.5302076935768127}
{"content": "One of the primary questions in CF is the so called\nq 1 sproblem. In a D/T mixture, some fraction of the muons captured in theexcited state of muonic deuterium can be transferred to the triton beforereaching the ground state with the probability (1-\nThere has been a longstanding discrepancy between theoretical predictions,based on semi-classical calculations, and experimental data derivedindirectly (see for example, Ref. [1,36]). Recentexperimental developments [37,38] using state-of-the-art Xray detection technologies are producing more direct information about\nq 1 s\nProcesses involving excited states,\nn>1, of the muonic atom have gainedincreasing theoretical attention. In addition to semi-classicalcalculations of excited transfer reactions [39,40], fullquantal calculations are emerging [41] using the hypersphericalapproach (Section 2.1.4). The transport cross sectionsof excited atoms including Stark transitions are being investigated mainlyin semi-classical approaches [42,43].\nRecently, a new process has been suggested by Froelich andWallenius [44,45,46]. They predict a high rate offormation of a muonically excited metastable three-body state (associated with the adiabatic 3potential [47]) in thecollision of excited with D\n2, which will then decay into,effectively reversing the transfer reaction:\nWe note that the side path model is unlikely to impact our measurements using emitted from layers, since the Ramsauer-Townsend effect is not expected for excited muonic atoms.", "pred_label": "__label__POS", "pred_score_pos": 0.660675585269928}
{"content": "Asyra Allergy Testing\nThe Asyra Health Screening system offers a non-invasive and effective system of allergy detection and elimination.\nAllergy, food intolerance and sensitivity issues are increasingly common. In most cases, allergic response to certain allergens has an underlying cause, reflecting weakness, imbalance, stress or nutritional deficiency elsewhere in the body. Effective therapy does not suppress the symptoms of allergy, but works to ease presenting symptoms as one stage of treatment, whilst assessing the underlying root of the issue and working to address this and strengthen the body, to minimise allergic tendencies.\nThe Asyra Allergy Desensitisation Protocol evaluates key allergens and substances causing allergic reaction or intolerance. These include a variety of food substances, such as the common triggers of wheat and grains, dairy, soy, nuts, sugar, meats etc, to other allergens such as grass, flower and tree pollens, animal hair, dust and moulds. A desensitisation remedy is then made of all identified allergens.\nThe patient is additionally evaluated for any underlying patterns of ill health and weakness that may be contributing to intolerance or reactivity. This includes any nutritional deficiencies that may be present, toxicity or digestive issues. A second remedy that addresses any causative issues is given alongside the Desensitisation remedy to support the Programme.\nPrinciples of Allergy Elimination\n1 Identify key allergens and desensitisation strategies 2 Create an individualized remedy for desensitisation 3\nSecond support remedy to address underlying\ncausative issues that may be aggravating or\ncausing allergic tendencies and to assist action of desensitisation remedy.\n4\nBuild health with customized healing template\nthrough nutrition, diet and lifestyle modification.", "pred_label": "__label__POS", "pred_score_pos": 0.522253692150116}
{"content": "Winter cover crops are grown infrequently by farmers in California’s Central Valley because dry seasons are common over the winter. The potential requirement for irrigation during a dry year serves as a barrier to increased implementation of cover crops and growers frequently leave fields fallow. This study was conducted at the USDA Natural Resources Conservation Service, Lockeford Plant Materials Center (PMC) with the objective to evaluate cover crop species as alternatives and additions to the standard triticale.", "pred_label": "__label__POS", "pred_score_pos": 0.9279447793960571}
{"content": "Abstract\nStudies of carbon nanotube (CNT) based composites have been unable to translate the extraordinary load-bearing capabilities of individual CNTs to macroscale composites such as yarns. A key challenge lies in the lack of understanding of how properties of filaments and interfaces across yarn hierarchical levels govern the properties of macroscale yarns. To provide insight required to enable the development of superior CNT yarns, we investigate the fabrication - structure - mechanical property relationships among CNT yarns prepared by different techniques and employ a Monte Carlo based model to predict upper bounds on their mechanical properties. We study the correlations between different levels of alignment and porosity and yarn strengths up to 2.4 GPa. The uniqueness of this experimentally informed modeling approach is the model's ability to predict when filament rupture or interface sliding dominates yarn failure based on constituent mechanical properties and structural organization observed experimentally. By capturing this transition and predicting the yarn strengths that could be obtained under ideal fabrication conditions, the model provides critical insights to guide future efforts to improve the mechanical performance of CNT yarn systems. This multifaceted study provides a new perspective on CNT yarn design that can serve as a foundation for the development of future composites that effectively exploit the superior mechanical performance of CNTs. (Chemical Equation Presented).\nAll Science Journal Classification (ASJC) codes Materials Science(all) Engineering(all) Physics and Astronomy(all)", "pred_label": "__label__POS", "pred_score_pos": 0.6690211892127991}
{"content": "The Global Learning for Adaptive Management (GLAM) is an initiative envisioned as a globally networked learning alliance that aims to actively identify, operationalise and promote rigorous evidence-based approaches to adaptive management. GLAM has a legacy of research on effective monitoring, evaluation and learning (MEL) for Adaptive management (MEL4AM) and a library focused on adaptive and MEL4AM work.\nThis brief explores the issues and learning related to work the USAID/Honduras Transforming Market Systems (TMS) Activity has been leading to support both public- and private-sector stakeholders to generate and use metrics and data for decision-making, setting economic growth agendas, building alliances, and adapt to changing circumstances.\nThe Summary outlines the ways in which DI’s use of collaborating, learning and adapting (CLA) mindsets and practices contributed to its development achievements.\nFrom February to June 2020, the DRG Center is hosting a series of virtual panel discussions titled \"The DRG Tipping Point.\"\nA guide on local philanthropy as an element of societal self-reliance.\nFor the USAID/Uganda School Health and Reading Program (SHRP) – implemented by RTI, adapting to improve results was at the heart of early grade reading efforts since the program started in 2012.\nThe USAID Resiliency in Northern Ghana (RING) Project had notable success in its first three years of integrated agriculture, nutrition, livelihoods and sanitation programming to improve nutrition and household resiliency within the most vulnerable homes in the Northern Region. One area of project focus is women’s...\nThe USAID/Bangladesh “Feed the Future Livestock Production for Improved Nutrition (LPIN) Activity” utilized Collaborating – Learning – and Adapting (CLA) from start to finish.\nUtilizing CLA approaches such as Pause and Reflect, the DREAMS attendees applied learning on MERS to determine areas within their project that could be made more market-aware.\nYouth unemployment and underemployment is a major development challenge around the world and particularly in Kenya which has one of the highest rates of youth unemployment globally. This case explores the CLA approach of Kenya Youth Employment and Skills Program (K-YES), a five-year program funded by USAID that enhances employment opportunities for unemployed and underemployed Kenyan youth (aged 18-35) who have not completed secondary education.", "pred_label": "__label__POS", "pred_score_pos": 0.8330655097961426}
{"content": "Stimulus-induced exocytosis of large dense-core vesicles (LDCVs) leads to discharge of neuropeptides and fusion of LDCV membranes with the plasma membrane. However, the contribution of LDCVs to the properties of the neuronal membrane remains largely unclear. The present study found that LDCVs were associated with multiple receptors, channels and signaling molecules, suggesting that neuronal sensitivity is modulated by an LDCV-mediated mechanism. Liquid chromatography-mass spectrometry combined with immunoblotting of subcellular fractions identified 298 proteins in LDCV membranes purified from the dorsal spinal cord, including G-protein-coupled receptors, G-proteins and other signaling molecules, ion channels and trafficking-related proteins. Morphological assays showed that δ-opioid receptor 1 (DOR1), β2 adrenergic receptor (AR), G(αi2), voltage-gated calcium channel α2δ1 subunit and P2X purinoceptor 2 were localized in substance P (SP)-positive LDCVs in small-diameter dorsal root ganglion neurons, whereas β1 AR, Wnt receptor frizzled 8 and dishevelled 1 were present in SP-negative LDCVs. Furthermore, DOR1/G(αi2)/G(β1γ5)/phospholipase C β2 complexes were associated with LDCVs. Blockade of the DOR1/G(αi2) interaction largely abolished the LDCV localization of G(αi2) and impaired stimulation-induced surface expression of G(αi2). Thus, LDCVs serve as carriers of receptors, ion channels and preassembled receptor signaling complexes, enabling a rapid, activity-dependent modulation of neuronal sensitivity.", "pred_label": "__label__POS", "pred_score_pos": 0.6434112787246704}
{"content": "Key international themes in coercion. Molodynski A., O'Brien A., Burns J.\nCoercion remains a dominant theme in mental healthcare and a source of major concern. While the presence of coercion is ubiquitous internationally, it varies significantly in nature and degree in different countries and is influenced by a variety of factors. Recent reports have raised concerns about physical restraint and the increasing use of legislation in high-income countries. At the same time, a recent Human Rights Watch report on pasung (the practice of tying or restricting movement more generally) in Indonesia has served to highlight the plight of many in middle- and lower-income countries who are subject to degrading and dehumanising 'treatment'.", "pred_label": "__label__POS", "pred_score_pos": 0.9628854990005493}
{"content": "Cities face the challenge of defining optimal strategies for an adaptive, resilient and low-impact urban development. In this context, Sustainable Drainage Systems (SuDS) arise as an innovative solution for stormwater management.\nThe CoSuDS project aims at promoting the transition towards smart stormwater management from a collaborative perspective, bridging the gap between pilot implementation to long-term city strategy. The project will co-develop a “CoSuDS Toolbox” to be used for defining transition pathways in cities, being applied at district level for a city in Spain and integrating multiple actors in the process through collaborative charrettes. The pilot district will become a reference example for further upscaling and replicability in Europe.", "pred_label": "__label__POS", "pred_score_pos": 0.9773877263069153}
{"content": "\"To prevent hackers from getting personal data of users, users don't need to use a VPN connection in their daily life\", said Yevgeny Lifshits, a member of the expert council of the State Duma Committee on Information Policy, Information Technology and Communications.\nHe explained that a VPN is a virtual network that is supposed to protect the user's personal data from hackers. It is assumed that using this network allows users to maintain network privacy. However, according to the expert, VPN services carry more danger than protection.According to Lifshits, such services are not needed in everyday life.\n\"Sometimes VPN services are necessary for work to transfer commercial data. In everyday life, they have no value.\"\nAccording to the expert, if a person does not commit crimes that he wants to hide with a VPN, then he does not need to protect himself. Otherwise, passwords may end up in the hands of hackers.\n\"A user installing a VPN believes that he has secured himself, but the service provider may allow a data leak,” said Lifshitz.\nAccording to him, if the VPN service is unreliable, hackers can get passwords and other personal data of the user. The expert noted that now there are thousands of companies offering a secure connection and an ordinary person can make a mistake with the choice of a reliable one.\nEarlier it was reported that the personal data of 20 million users of free VPN services were publicly available on the Internet. Experts found on the open server email addresses, smartphone model data, passwords, IP addresses, home addresses, device IDs, and other information with a total volume of 1.2 terabytes. It is noted that the leak occurred from networks such as UFO VPN, Fast VPN, Free VPN, Super VPN, Flash VPN, Secure VPN and Rabbit VPN. Some of them have millions of downloads from Google Play and the App Store and high ratings.", "pred_label": "__label__POS", "pred_score_pos": 0.9003344774246216}
{"content": "Download for free:Download PDF Paperback 978-971-560-160-3 e-ISBN 978-971-560-227-3\nThe Philippine Census of Agriculture (CA), which reflects the performance of the agricultural sector through the years, presents data essential in effective implementation of strategic policies and resolutions to improve agriculture in the country. The National Statistics Office (NSO) is responsible for gathering data for the CA, which began in 1960 and has since been conducted every decade. A complete count of all farm operators in the Philippines, the CA collects data on the basic structural characteristics of each farm (e.g.,\nsize and location, tenure status, main use of land, crops planted, livestock or poultry raised, agricultural practices, type of irrigation used, farm equipment or machineries used, and demographic characteristics of the agricultural operators and their household members).\nThis study analyzed the results of the 2002 CA and compared it to the findings of the 1991 Census of Agriculture and Fisheries (CAF) to determine if the agricultural sector improved because of policy change, technological improvement, or a shift in demands or other factors. To meet the study objectives, the following variables were explored: farms and farm sizes, cropping pattern vis-à-vis irrigation system, shift in major crops and geographical variation in cropping density, shift in land use, and tenure of holdings. Their differences across time and/or space were also assessed.\nThe CA collected information from sample barangays to represent each city or municipality, except for some provinces that were completely enumerated. In the 2002 CA, the provinces of Batanes, Isabela, Laguna, and Bukidnon were completely enumerated. Meanwhile, in the 1991 CAF, these provinces and the province of Marinduque were completely enumerated. For this study, a region was picked from the three broad island groups. The region within the island group was selected based on the enumerated number of farms and the variety of planted crops reported. The region with the highest number of farms and the most varied crops planted within the island group was analyzed. Region II, Region VI, and Region X were selected for Luzon, Visayas, and Mindanao, respectively.\nThe study showed that from 1991 to 2002, the number of farms had increased while farm area and average farm size had decreased. This did not apply to Region II, which experienced an increase in farm area. However, a generally decreasing trend of the computed Gini coefficients for both regions and provinces signaled a improvement in farm distribution. This indicates a more equal distribution of farms in 2002 than in 1991.\nAll the three regions practiced cropping patterns that chiefly involved temporary crops, with palay and corn as the top two temporary crops planted in terms of the number of farms. In terms of area planted, palay was the most dominant temporary crop in the three regions. Corn was another dominant temporary crop in Region II and Region X while sugarcane was another dominant temporary crop in Region VI.\nFor palay farms, the same-crop pattern was practiced more than the different crop pattern in 1991 and 2002. In all regions, the coverage of irrigation systems improved. This could have been a result of the government’s irrigation programs. The volume of production from irrigated palay farms improved as well. The most common irrigation system in both years was the national irrigation system.\nFor corn, the dominant cropping pattern in Region II and Region X in 1991 and 2002 was the same-crop pattern. Meanwhile, the different-crop pattern was practiced more in Region VI. In 2002, the irrigation system that was commonly used in corn farms in the three regions was “others,” which included water fetching and windmills. As in palay farms, the use of irrigation for corn farms likewise increased.\nBanana and coconut were among the top five permanent crops in Region II, Region VI, and Region X from 1991 to 2002. Region X shared the highest number of banana hills and coconut trees, the largest land area planted with banana and coconut, and the least cropping density for both crops. In the three regions, both crops showed a decreasing trend in farm area, which could be attributed to shift of crop, conversion to non-agricultural land, and the implementation of Comprehensive Agrarian Reform Program (CARP). An\nupward trend was also noted in the cropping density of banana and coconut in the three regions as a means of increasing production to meet local and global demand for said crops. In terms of the number of farms and farm area, there was no major shift in main land use in the three regions from 1991 to 2002. Farms were used in raising temporary crops, of which rice and corn, being the staple food of the Filipinos, shared the largest portion. The portion of farms with homelot as the main land use rose in the three regions. This can be attributed to the programs addressing housing needs, especially for the urban poor. Region X indicated a major shift in the second most common land use, from permanent crops in 1991 to homelot in 2002.\nThe most common form of tenure status in the three regions was fully-owned/owner-like possession. Tenure status improved in Region II and Region VI, which indicates the effect of CARP implementation. However, such improvement was not observed in Region X.", "pred_label": "__label__POS", "pred_score_pos": 0.5476942658424377}
{"content": "A proactive approach to change\nChapters 1 and 2 have already introduced a wide range of dimensions and factors that can be incorporated within the corporate configurations model. However, the model is not yet complete. We still need to refine the axes used on both sides of the rainbow and we need to consider when and how companies will move around the model. These ideas are introduced in this chapter. When the high and low scales are properly incorporated on both\naxes of themodel it becomes clear that there canbe considerable confusion caused if certain positions within the model are occupied by the corporate centre. However, it can sometimes be less clear precisely what action such a centre should take to move itself to a sustainable value-adding situation. It should also already be clear from the preceding chapters that any\ngroup may need, or wish, to alter its current positioning within the model. This may be in response to a change in its external business environment, its own internal organisation, or simply to improve the effectiveness of its current corporate strategy. In this chapter, the general implications of such matters are consid-\nered. The simplest type of move is a repositioning within an existing corporate configuration; what we refer to as migrations within the model. Transitions across the model involving changing from one configuration to another are normally muchmore complicated, particularly if the organisation is trying to move dramatically around the model, rather than moving just across the boundary into the nextdoor configuration. The detailed, specific issues involved in moving just across the boundary to the next configuration in the model are\ndealt with, for each configuration, in Chapters 4 to 7, which deal individually with the controls, scale, scope and creative configurations. The more complex transitions around the model are then considered in Chapter 8 in Part III of the book.", "pred_label": "__label__POS", "pred_score_pos": 0.5986152291297913}
{"content": "ATO Extension of Home Office Claim\nFor many Australian workers, COVID-19 has meant abandoning the daily commute and working from home. In response, the ATO has announced a temporary simplified short cut method to make it easier for individual taxpayers to claim deductions for additional running expenses incurred (e.g. heating, cooling, lighting, equipment, internet costs), as a result of working from home.\nEligible individuals will be able to claim a deduction for all running expenses incurred during the period\n1 March 2020 to 30 June 2020, based on a rate of 80 cents for each hour an individual carries out genuine work duties from home. This is an alternative method to claiming home office expenses under existing arrangements, which generally require an analysis of specific running expenses incurred and more onerous record-keeping.", "pred_label": "__label__POS", "pred_score_pos": 0.5473843216896057}
{"content": "EMDR EMDR and Trauma\nIn the context of EMDR (Eye Movement Desensitization and Reprocessing), trauma is conceived\nas any experience that activates the fight-or-flight response but does not resolve. For example:\n\"A soldier is traumatized by a bomb that has detonated in front of him. When the bomb goes off,\nthe soldier dives for cover. When the smoke clears, he realizes his fellow soldier has been killed.\nThe soldier is numb, paralyzed mentally, and thinks \"I survived at the expense of my buddy\".\nWhen the soldier returns home, he is startled by loud noises, especially explosive ones such as\noverhead planes and cars backfiring. He dives for cover when he hears a low flying jet overhead.\nHe feels guilty. His guilt intensifies when he watches the news and hears about the deaths of\nsoldiers. He has difficulty falling asleep and when he does fall asleep, he frequently has\nnightmares. When he is awake, he is irritable, hypervigilant, anxious, and sometimes\nexperiences flashbacks.\nIn the EMDR context, this trauma is an experience which has not been put into narrative memory.\nThe experience is still alive, and is activated by triggers in his current life. It is as if the bomb is\ncontinually exploding in the present. The experience is encoded with negative beliefs about\nhimself such as \"It's my fault that my buddy died\" or \"I don't deserve to live.\"\nWHAT IS EMDR?\nEMDR or Eye Movement Desensitization and Reprocessing is a trauma protocol that works with\nmemory networks. It is a tool for processing experiences that are still \"alive\", as with the soldier\nwho dives for cover when a plane flies overhead by putting those experiences into narrative\nmemory. During EMDR, the soldier is guided by the clinician, through his traumatic experience so\nthat it no longer is disturbing. So that the negative belief \"I don't deserve to live\" can be replaced\nby a positive belief, such as \"I am a survivor\" or \"I deserve to live.\" When the experience is fully\nprocessed, the soldier may still feel sad or angry about what happened, but the experience is no\nlonger disturbing or \"alive\". It is in the past: it is now a memory. He can live in the present\nwithout nightmares, flashbacks, or feelings of guilt.\nTHE EMDR CONTEXT\nEMDR is implemented in the context of a therapeutic relationship with a clinician that has been\nproperly trained through EMDRIA (Eye Movement Desensitization and Reprocessing Institute of America) certified trainings.\nYou should never do EMDR with a clinician who is not trained and certified through EMDRIA approved trainings.\nBefore implementing EMDR, the clinician takes time to get to know the client and to ensure that\nthe client is well informed, feels safe, and empowered to engage fully in processing, The\nclinician will take a thorough Trauma and Attachment history. The clinician will also facilitate client\nawareness of the client's disturbance levels, and teach self-soothing techniques which may\ninclude installing a SAFE PLACE, as well as creating a psychological CONTAINER in which the client\ncan store traumatic experiences so that they do not continue to interfere with present day\nfunctioning. The clinician will reinforce existing client strengths and install positive coping\nmechanisms so that the client can manage daily stressors. The clinician takes care not to engage\nin processing until the client is ready and addresses present stressors before moving into\nprocessing disturbing material from the past.\nHOW DOES EMDR WORK? EMDRreplicates REMor Rapid Eye Movement which we all experience in deep sleep. We\nhypothesize that psychological content is processed in deep sleep. That is why professional\nathletes, for instance skiers, will watch movies that simulate the downhill course the night before\nthey perform. During REM sleep or by repeatedly watching and practicing the downhill course, the athlete will \"ski\" the course he is to\nperform. On the day of performance, the skier is able to precisely follow the course encoded in his\nmemory during REM sleep, or by repeatedly watching/practicing the downhill course. In EMDR, as in REM, the client moves his eyes from left to right and back again, stimulating both sides of his brain and integrating left brain logic with right brain\ncreativity. Thus,\nEMDRis also known as bi-lateral stimulationof the brain.\nAlthough eye movements are most typically used; tapping, auditory clickers or buzzers placed in\nthe client's hands, alternating left and right can be used if eye movements are not comfortable for\nthe client.\nThrough EMDR, the client is safely supported by the clinician while he or she travels through the\ntraumatic experience. EMDR is often more effective and efficient than talk therapy because it\ntargets a specific memory, processing and integrating all aspects of the targeted\nexperience: images, thoughts, sounds, smells, emotions and body sensations.\nEMDR is completely client centered. Once EMDR processing begins, the clinician stays out of the\nway of processing. The clinician implements the bilateral stimulation, stopping after sets that\ntypically include 6 to 30 sets of left right (bilateral) movement. At each break, the client is\ninstructed to take a deep breath, and notice thoughts, feelings, sensations. With each set, the\nclient experiences the traumatic material with less disturbance and more empowerment. The goal\nis to reach a zero level of disturbance around the target experience, and to replace a negative belief such as\n\"I don't deserve to live\" with the positive belief, e.g. \"I survived, I deserve to live.\"\nClients who have struggled through years of talk therapy often report significant relief, and the\nability to experience peace and joy after going through EMDR treatment, sometimes after just a\nfew sessions.\nEMDR is getting past your past so that you can be fully present to your life.", "pred_label": "__label__POS", "pred_score_pos": 0.6201688647270203}
{"content": "Improved resilience has emerged as a top priority for the U.S. power grid. Efforts to mitigate wildfire risk in Northern California last year led to hundreds of thousands of electricity customers being disconnected from the grid. During hurricane season, customers in the Eastern and Southern U.S. often face the associated threat of multi-day power outages. In many other parts of the country, portions of the local power grid are susceptible to interruptions due to a variety of other factors. Improved resilience would reduce or avoid those outages, allowing industries, businesses, and households to maintain their uninterrupted supply of electricity.\nResilience can be improved through the deployment of microgrids, among other options such as vegetation management and circuit hardening. Microgrids have been described in a wide variety of ways. Simply put, the term “grid” refers to a combination of power generation, customers who consume the power, wires that deliver the electricity to customers, and a control system that manages this process. As discussed in this paper, a microgrid simply is a small, self-sufficient grid.\nSome types of microgrids provide resilience by serving load locally. If portions of the power grid are temporarily turned off to prevent wildfires or if a transmission line is taken offline during a hurricane, microgrids “downstream” of those interruptions continue to keep the lights on by providing power from local resources.\nParallel to the search for improving grid resilience is a strong focus among utilities and policymakers on a cleaner U.S. power supply, with goals to limit greenhouse gas (GHG) emissions and improve local air quality. Twenty-one utilities and 23 states have committed to massive reductions in electricity generation emissions – typically reductions of 80% or more – over the next 10 to 30 years.", "pred_label": "__label__POS", "pred_score_pos": 0.5368152856826782}
{"content": "Short-term crude oil prices\nCrude oil prices have rallied almost 30% since the low in February 2016. However, they have fallen almost 6% in 2016 due to record supplies from the US to Russia. Oil prices are still following the long-term bearish trend. The US crude oil inventory is crucial for crude oil prices in the short term.\nKey support levels\nShort covering and lower crude oil prices could support crude oil prices. Crude oil prices could see resistance at $37 per barrel. Prices hit this mark in November 2015. In contrast, rising production from Iran and the appreciating US dollar could drag crude oil prices lower. The key support for crude oil prices is $25 per barrel. Prices tested this mark in 2003.\nCrude oil price forecast\nA recent poll from Reuters suggests that crude oil prices could hit $40 per barrel in 2016. Morgan Stanley estimates that crude oil prices could average around $30 per barrel in 2016. The U.S. Energy Information Administration estimates that Brent crude oil prices could average $38 per barrel in 2016 and $50 per barrel in 2017. WTI (West Texas Intermediate) oil prices could average $38 per barrel in 2016 and $50 per barrel in 2017. On the other hand, the National Bank of Abu Dhabi suggests that crude oil prices could test $20 per barrel in the short term due to fragile economic conditions in the Middle East and North Africa region. Read How Are Oil Prices Squeezing OPEC Members’ Budgets? to learn more.\nThe recent uptick in crude oil prices benefits oil and gas producers like Petrobras (PBR), Devon Energy (DVN), Chevron (CVX), Noble Energy (NBL), PetroChina (PTR), Apache (APA), WPX Energy (WPX), and PDC Energy (PDCE).\nThe volatility in crude oil prices impacts ETFs and ETNs like the iShares Global Energy ETF (IXC), the iShares U.S. Energy ETF (IYE), the iShares U.S. Oil Equipment & Services ETF (IEZ), and the VelocityShares 3x Long Crude Oil ETN (UWTI).", "pred_label": "__label__POS", "pred_score_pos": 0.9564000368118286}
{"content": "Lead Counsel independently verifies Mesothelioma attorneys in Lynbrook by conferring with New York bar associations and conducting annual reviews to confirm that an attorney practices in their advertised practice areas and possesses a valid bar license for the appropriate jurisdictions.\nMesothelioma, a rare form of cancer that develops in the protective lining of many internal organs, is caused by exposure to asbestos, such as inhaling or ingesting asbestos in the workplace. Symptoms of mesothelioma may not appear for 20 to 50 years after the exposure.\nYou can sue for damages, and if whoever exposed you to asbestos knew asbestos was present, you may also seek damages to punish the party who negligently exposed you to asbestos. To protect your rights you should hire a Lynbrook asbestos attorney to file your lawsuit and be your advocate.\nAn attorney can often resolve your particular legal issue faster and better than trying to do it alone. A lawyer can help you navigate the legal system, while avoiding costly mistakes or procedural errors. You should seek out an attorney whose practice focuses on the area of law most relevant to your issue.\nThe goal of an initial consultation is to find an attorney you are comfortable working with and someone who can help you understand your options under the law. Seek to understand the relevant legal experience the attorney brings to your case. While it is not realistic to expect an attorney to resolve your legal issue during an initial consultation, you should gain a level of comfort with his/her ability to do so. A good consultation can clarify issues, raise pertinent questions and considerations for your case, and help you make an informed decision towards resolving your legal issue.\nPro se – This Latin term refers to representing yourself in court instead of hiring professional legal counsel. Pro se representation can occur in either criminal or civil cases. Statute – Refers to a law created by a legislative body. For example, the laws enacted by Congress are statutes. Subject matter jurisdiction – Requirement that a particular court have authority to hear the claim based on the specific type of issue brought to the court. For example, the U.S. Bankruptcy Court only has subject matter jurisdiction over bankruptcy filings, therefore it does not have the authority to render binding judgment over other types of cases, such as divorce.", "pred_label": "__label__POS", "pred_score_pos": 0.5292719006538391}
{"content": "You might have a small business where only a handful of people work. Or, perhaps, you have a larger facility that sees a lot of foot traffic. Regardless of size, hazardous events, particularly fires, might deal a fatal blow. Commercial fires might happen anywhere, at any time and could harm a lot of people. Then, when you start to pick up the pieces, you might have to rely heavily on your\nbusiness owners policy (BOP). However, your BOP will only cover fire losses up to a certain limit. Therefore, the right risk management can help you keep fire risks low, even though you can’t avoid every risk. BOP Coverage for Fire Damage\nOften, your BOP can address the costs of damage caused by in-store fires. It might provide:\nProperty coverage that pays for damage to your building and possessions. It might pay for stock and inventory, damaged furnishings and related items.\nLoss of use/Business interruption insurance will apply to situations where fire damage forces you to stop operations until you can recover. The coverage can help you cover essential costs that might still exist in the interval. It might help you pay client salaries and ongoing bills during the closure.\nIf a client or other party gets hurt in the fire, they might sue the business for negligence. In these cases, general liability insurance might compensate them for their medical costs. Liability coverage might also apply if the fire spreads from your building to other peoples' property and damages them.\nStill, not all losses will have coverage under your BOP. For example, if an employee gets hurt in the fire, then they might qualify for workers’ compensation. You will have to buy a separate policy for this loss.\nKeeping Fire Risks Low in the Business\nAny responsible business owner should take proper fire safety steps. The more you follow guidelines, the more you might reduce the likelihood of a fire occurring.\nDon’t burn candles or other exposed flames on the premises (unless you work in an environment where this is a common practice).\nEnsure that your building meets fire safety codes. You will need a smoke alarm at minimum. You might also need emergency lighting, fire extinguishers and even fire hose hookups.\nPlace maps with escape routes in prominent areas of the business.\nKeep walkways clear and open.\nHave you electricity and HVAC systems inspected regularly, especially if you notice signs of malfunctions.\nNever use equipment or flammable materials in unsafe or non-specified ways.\nIf a fire does occur, don’t hesitate to contact your BOP provider. They can help you determine how you can best file a claim for the costs of the damage.\nAlso Read: What Does a Business Owners Policy Cover?", "pred_label": "__label__POS", "pred_score_pos": 0.7580846548080444}
{"content": "The maritime sector plays a vital role in the UK economy and continues to provide vital freight and key worker services throughout the pandemic. However, it has faced significant disruption and challenges, as have many parts of the economy. To support businesses and employees, HMG has responded with an unprecedented £330 billion of financial measures. In addition, the Department provided bespoke financial support to ensure that critical lifeline and freight services continued to operate through the most challenging period.\nMy Department is working closely with the maritime sector on their restart plans. This includes identifying the support that will need to be provided to enable the safe resumption and continued increase of services and operations. We are also working with the sector on a longer-term Maritime Recovery Plan which will build on Maritime 2050 published in January 2019. Given the changes that COVID-19 has caused, we are considering where new recommendations could be made in addition to Maritime 2050, or existing recommendations accelerated, to help the maritime sector recover from COVID-19 and continue to grow.", "pred_label": "__label__POS", "pred_score_pos": 0.5924451351165771}
{"content": "In the WYBSL, the safety of our players, parents, spectators, coaches, umpires and staff is paramount. In these tumultuous times, it is everyone’s responsibility to do their part to prevent the spread of COVID-19.\nFollowing the guidelines established by the State of Ohio, Department of Health and in consultation with the City of Westerville, the WYBSL has put specific plans in place to help combat this virus. We ask that everyone do their part to ensure a safe season by understanding the steps we are taking:\nCOVID Mandatory Guidelines\nThe following guidelines are to be implemented at all times by all WYBSL participants and spectators to ensure everyone’s safety. The coach(es) are held responsible for following and implementing all required guidelines:\nThe Coach must keep a complete list of coaches and players present at each practice and game. This list shall include the date, beginning and ending time of the practice/game, names, addresses and phone contact of all players and coaches to be made available upon request from the local health department. (Roster will be provided with names, address and contact information) All participants and spectators must adhere to six-foot physical distancing while outside of the field of play and dugouts. All participants and coaches must conduct symptom assessments (self-evaluation) before arriving to the fields. Anyone experiencing symptoms 1must stay home. No team water coolers or shared drinking stations. Athletes and Coaches should use individual water containers. Compliant game balls must be designated to each team for use while that team is playing defense. Face coverings for coaches are recommended, but not required, in the field of play and dugouts. Athletes must wear face covering when not in the field of play or dugouts, if unable to maintain a 6ft distance Face coverings are currently required for spectators, if unable to maintain a 6ft distance. Line-ups will not be passed between the teams or score keepers. Upon the third out, the “put out player” should bring the designated defensive game ball back to their respective dugout. Athletes are strongly recommended to travel to the venue only with members of their immediate household, if possible. Face coverings are currently required while walking to the fields if unable to maintain a 6ft distance. Whenever possible, equipment and personal items should have proper separation and should not be shared. If equipment must be shared, proper sanitation should be administered between users. No touch rule – players should refrain from high fives and other physical contact with teammates, coaches and spectators. Spectators must not enter the field of play, which includes the bench and field areas. Spitting, eating seeds, gum or other similar products are strongly discouraged. Individuals should not congregate in common areas and/or the parking lot following the event or practice. If you become aware of a confirmed case of one of your players or a player’s family, contact the league and we will contact the local health district about suspected cases or exposure.\nHead coaches are responsible to follow and practice the mandatory guidelines to ensure player, coach and spectator safety.\n1 Per the CDC, symptoms include cough, shortnessof breath or difficulty breathing, fever, chills, muscle pain, sore throat, and new loss of taste or smell. Equipment Sanitation\nIt is recommended that equipment not be shared by players. Where this is not possible, the WYBSL has put a sanitation procedure in place. This applies to equipment such as bats, helmets, catcher’s gear, baseballs & softballs.\nThe league will provide all coaches with an EPA approved disinfectant approved for use against COVID-19 and stands ready to re-supply it whenever necessary.\nWe encourage the use of a designated bench coach/volunteer to monitor this procedure.\nContact Tracing\nCoaches will use their rosters and designated “contact tracing” forms to document the coaches and players at each practice. Line-up/scorebooks will serve the same purpose for games. This is necessary should any contact tracing be necessary.", "pred_label": "__label__POS", "pred_score_pos": 0.9102368354797363}
{"content": "Community Submission - Author:\nHenrique Erhardt\nTotal supply refers to the number of coins or tokens that currently exists and are either in circulation or locked somehow. It is the sum of coins that were already mined (or issued) minus the total of coins that were burned or destroyed.\nTherefore, the total supply includes both the circulating supply and the coins that are yet to hit the open market. For instance, coins that are being held under a lockup or vesting period, which typically follows a private sale or Initial Coin Offering (ICO) event.\nIn contrast to the total supply, the circulating supply refers to all coins that are already circulating and available for trading in the various cryptocurrency markets. The circulating supply refers to the coins that are already in the hands of the public and, as such, does not include coins or tokens that are locked up or being held in reserve.\nSince the market prices of a cryptocurrency coin cannot be directly affected by the part of the supply that is locked or reserved, the calculation of market capitalization normally considers only the circulating supply instead of the total supply.\nWhile the total supply includes all coins that were already mined (or issued) minus the ones that were burned, the max supply refers to all coins that will ever come into existence. Unlike the total supply, the max supply includes the coins that are yet to be mined (in the future), along with the ones that are part of the total supply and also the ones that were burned.\nFrom a cryptoeconomics point of view, many coins are valuable due to their inherent scarcity. For example, Bitcoin and other mineable coins are generated every time a new block is validated by a miner (and confirmed by the rest of the network). However, the generation of new coins is not an infinite process as most of the mineable cryptocurrencies have a cap (max supply) that limits the number of coins that can be generated. The max supply is usually defined at the moment the genesis block is created.", "pred_label": "__label__POS", "pred_score_pos": 0.5498642921447754}
{"content": "In a historic collective bargaining round between General Motors and the United Auto Workers, nearly 50,000 UAW members began a strike against GM on September 16, 2019. Key issues in the strike included GM's tiered employee wage structure, healthcare benefits, job security, pensions, and GM’s treatment of temporary workers.\nThe 2019 UAW-GM strike affected individuals, families, and the communities that rely on GM to sustain their way of life. Though the strike has ended, the memory of the UAW members' fight is still vivid in the minds of those who lived it.\nSchool of Human Resources and Labor Relations Assistant Professors Dr. Maite Tapia and Dr. Christian Lyhne Ibsen in collaboration with UAW International Representative (Ret.) Mark Strolle, conducted a survey of striking GM workers at two Locals in Lansing, Michigan, UAW Local 602 and Local 652. The purpose of the survey was to understand the workers' attitudes towards the strike, the support they received, as well as the strength of worker-union relationships.\nLead researchers: Maite Tapia (tapiam@msu.edu) and Christian Lyhne Ibsen (ibsenchr@msu.edu), Assistant Professors, Michigan State University, Mark Strolle (strolle@msu.edu), UAW International Representative (Ret.)\nFull MSU team: Philip S. Deortentiis, Asst. Prof; Carla Lima Aranzaes, PhD student; Dasom Jang, PhD student; Caroline Brown, Graduate student; and Dana Staublin, undergraduate student.", "pred_label": "__label__POS", "pred_score_pos": 0.5343483686447144}
{"content": "Abstract\nFoodborne diseases cause approximately 76 million illnesses, 325,000 hospitalizations, and 5000 deaths each year in the United States. The authors present and analyze information derived from epidemiologic investigations and surveillance systems on foodborne infections caused by consumption of molluscan shellfish. This review focuses on the bias in reporting of shellfish-vectored illness, prevention and control of such infections, the origin of recognized viral and bacterial etiologic agents, and a new potential public health threat of a food-and-waterborne protozoan contaminant, Cryptosporidium parvum.\nASJC Scopus subject areas Gastroenterology", "pred_label": "__label__POS", "pred_score_pos": 0.7139825224876404}
{"content": "I buried my head in my pillow, the soft fabric muffling my frustrated screams. I hate it. I hate it, I hate it, I hate it.\nI was low. AGAIN. It seems to be the trend lately. My efforts to keep my blood sugars from spiking has resulted in more lows. Lows that seem unexpected because I really thought everything I was doing seemed right. Lows that have been incredibly disruptive, making me stop whatever activity I’m doing. Stubborn lows, that a couple glucose tablets don’t seem to solve. Lows that wake me up at night, lows that won’t go away, lows that leave me feeling awful. And upset. And frustrated.\nI don’t want to treat the low. I’m tired of stuffing my face with sugar, not because I want it, but because I need it. I’m tired of working so hard in my workouts, only to have to later eat everything I burned off or sit out because I can’t continue with a low. I’m especially tired of eating when I’m not hungry and feeling awful while I wait for my blood sugar to stabilize.\nI can see the extra weight creeping on, and I hate it. I hate that I don’t have a choice when I’m low. I hate that those forced extra 80 calories of my fruit snacks add up. I hate that insulin makes it harder to lose weight. I hate that these lows are often then leading to later highs, sending me on a blood sugar roller coaster. I hate not feeling my best.\nI’ll talk to my doctor, I’ll make adjustments. We’ll work to get rid of these lows. But for now I just want to scream into my pillow and wish for the day when all of this will disappear. When sugar will just be sugar and not a substance that often feels like its controlling my life.\nSome days, weeks, months are better than others. I’ll make it through this rut, I know I will, but today, right now, I really hate my diabetes.", "pred_label": "__label__POS", "pred_score_pos": 0.972434401512146}
{"content": "Performance Management Performance management (PM) includes activities which ensure that goals are consistently being met in an effective and efficient manner. Performance management can focus on the performance of an organization, a department, employee, or even the processes to build a product of service, as well as many other areas. PM is also known as a process by which organizations align their resources, systems and employees to strategic objectives and priorities. Performance management features a process for managing both behavior and results, two critical elements of what is known as performance.", "pred_label": "__label__POS", "pred_score_pos": 0.7190309166908264}
{"content": "A safe and effective dengue vaccine has been lacking and the results of the study, which was conducted in 5 endemic countries in Latin America and the Caribbean, show a significant efficacy against the disease and high efficacy against its severe forms. These results confirm those of another study conducted in Asia and published 2 months earlier. They suggest that this vaccine could be a useful tool for public health, used in synergy with vector control measures.\nPDC is working with international health agencies, dengue experts and leaders in public health to integrate novel tools for the prevention and control of dengue. Dengue vaccines, used in combination with mosquito control, antiviral drugs and innovative models for epidemiological surveillance, will be vital to effectively and sustainably control dengue in endemic countries.", "pred_label": "__label__POS", "pred_score_pos": 0.60986328125}
{"content": "On February 10, 2017, Shin & Kim successfully defended Korea’s largest broadcasting company against a lawsuit by its employees seeking approximately KRW 185 billion in unpaid wages. The total number of plaintiffs numbered 2,257, of which 1,599 remained when the final judgment was rendered.\nValidity of Comprehensive Wage Agreement The plaintiffs, who had served in the broadcasting, technical and management departments, among others, alleged that the company did not pay the required overtime allowances (which include overtime, nighttime, and/or holiday payments) as provided for under the Labor Standards Act. Representing the broadcasting company, Shin & Kim argued that the plaintiffs had agreed to a valid comprehensive wage agreement where a portion of total overtime allowance would be included as part of their basic salary and the remainder of the overtime allowance would be determined by the number of hours actually worked by the employee. As part of our argument, we asserted that it was difficult to determine the actual number of hours worked by employees due to the nature of the work in broadcasting, but regardless the company’s payments were sufficient to cover overtime allowance and therefore the comprehensive wage agreement was not unfairly disadvantageous to the employees and should be recognized as valid.\nThe Seoul Southern District Court agreed and ruled the comprehensive wage agreement was valid and that the company had satisfied its obligations under the comprehensive wage agreement to pay the required overtime allowances under the Labor Standards Act.\nSignificance of the Judgment The present judgment is especially meaningful because in a recent, related case, the Korean Supreme Court did not acknowledge the validity of a comprehensive wage system in principle, making it difficult for employers to defend against lawsuits attacking the validity of comprehensive wage agreements. However, despite the uncertainty surrounding the recent Supreme Court decision, Shin & Kim was able to successfully argue that the comprehensive wage agreement entered into between the company and its employees was fair and valid with respect to the calculation of overtime allowance.\nShin & Kim is a leader in labor and employment law with extensive experience, expertise, and a remarkable track record. Additional successful representations include our representation of Korea Train Express (KTX) against a claim brought by crew members regarding dispatched workers, our representation of Ssangyong Motor Company in a dispute with its labor union, and our representation of Korea Development Bank regarding its merit-based wage system, among many others.", "pred_label": "__label__POS", "pred_score_pos": 0.991180956363678}
{"content": "Why a one metre passing rule?Cyclists need to ride one metre from the curb or parked cars to avoid getting doored. To illustrate this, I measured the amount of space it takes for a Honda Civic to open and it is just about one metre per the picture below. If a cyclist needs one metre to avoid getting doored (or curbside obstacles such as manhole covers), it is only fair they have such space on both sides to maximize their safety. Factor in handlebar widths and motor vehicles would likely have to move over to the adjacent traffic lane; therefore letting the cyclist take the lane. To understand what it feels when somebody gets too close to you, Santa Rosa’s Street Smarts Program produced this public service announcement.\nBicycle with pool noodle (via Warren Huska)\nWhile this idea was not copied from elsewhere and I hadn’t previously heard of it, a similar idea was used to highlight how much space drivers take by attaching a wireframe around the bicycle resembling a car’s dimensions of approximately five metres by two metres.[2] These two measures, among others, go to show how cycling related issues can be made aware in unconventional ways.\nBe inspired!\nRob Z (e-mail)\nFollow @RZaichkowski\n---\n[1] http://www.mto.gov.on.ca/english/safety/bill-31.shtml\n[2] Laura Bliss.\nCityLab. “If Bicycles Took Up as Much Space as Cars …” October 9, 2014. http://www.citylab.com/commute/2014/10/if-bicycles-took-up-as-much-space-as-cars/381300/.", "pred_label": "__label__POS", "pred_score_pos": 0.588740348815918}
{"content": "Abhinand C and Shilpa Rajeev, two students from the Government College of Engineering in Kannur, Kerala, have bagged the first prize of $10,000 at the recently concluded CODE19 online hackathon against coronavirus in India. Their winning entry, called iClassroom, involved a modern virtual classroom for the millennial generation. It connects students with teachers through a social media-type interface for uninterrupted learning in the time of the pandemic.\nThe 72-hour online hackathon was hosted by the US-based Motwani Jadeja Family Foundation. It saw thousands of innovators and developers from India and abroad compete online from the comfort of their homes to create open-source solutions against the Coronavirus crisis facing the nation.\nSaid 19-year-old Abhinand C: “Our winning entry was a virtual classroom that makes learning easier and more intuitive by providing an engaging peer-to-peer social media-type platform. It enables students and teachers to interact with each other, clear their doubts, mentor others and conduct online classes. We developed iClassromm as a dedicated platform for students to continue with their studies uninterrupted in the prevailing pandemic conditions. It serves as a tool for enhanced learning within and outside physical classrooms.”\nSaid 20-year-old Shilpa Rajeev: “We built this platform as a practical solution for all learning communities to interact with each other, share resources and keep track of progress in chosen courses, rather than use multiple communication tools for this purpose. We now intend to enhance iClassroom’s functionality by integrating several useful apps.”\nSaid well-known entrepreneur, investor, philanthropist and change agent Ms Asha Jadeja Motwani, the Founder of Motwani Jadeja Family Foundation which hosted CODE19 online hackathon: “We were overwhelmed by the high quality of entries received and the deep enthusiasm shown by all the participants. A community of hackers and mentors, especially young students from all parts of the country, came together to enable India’s fight against Coronavirus. I believe the qualitative, open-source projects created at this hackathon would help mitigate the impending Corona-inflicted challenges in India. I am hopeful that the total prize money of $34,000 awarded to winning teams will enable them to realize their solutions and bring them to market.”\nThe second prize of $5,000 was claimed by six students of Manipal Institute of Technology for enabling remote diagnosis of Covid19 patients to reduce the risk of infection for healthcare workers. Their solution, TeleVital, captures a patient’s vital statistics remotely through a Web cam and browser.\nThe third position was divided into three categories, with each of the three winning teams awarded $3,000 as prize money. The winners included SoloCoin which gamifies social distancing by allowing people to earn “solo coins” by staying at home and redeeming them for rewards from various merchants; the Covid19 Fact Checker, a fake news checker that leverages authentic government, scientific, and public health information to bust misinformation about the Covid19 pandemic; and Grape Community, an open platform that connects people with their neighborhood shopkeepers and suppliers. In addition, 10 best innovative solutions were awarded $1,000 each at the hackathon.\nCODE19 was organized by the Motwani Jadeja Family Foundation in collaboration with partners such as TIE Mumbai, IAMAI Startup Foundation, Mumbai Angels Network, Association of Designers of India, Stumagz and GirlScript. The event had three leading academic institutions as partners – National Institute of Design (Ahmedabad), IIT Kharagpur and Centre for Entrepreneurship – Ashoka University.", "pred_label": "__label__POS", "pred_score_pos": 0.8794535398483276}
{"content": "Abstract\nRecent research on snow cover patterns over recent decades is reviewed for GB. Interpretation for upland areas is complicated by data availability issues. Nevertheless, two distinct features can be highlighted. Firstly, a general relationship of average yearly snow cover duration with mean temperature. This relationship is apparently non‐linear indicating that snow cover duration is especially sensitive to a defined mean temperature range. Secondly, that snow cover can be rather variable from year to year, or over multi‐year phases. This variability has been related to the frequency of synoptic‐scale atmospheric circulation patterns including the North Atlantic Oscillation. These two features are used to contextualise recent and likely future trends in snow cover. It is suggested that there may be different patterns of variability in some mountain areas compared to the adjacent lowlands. This is associated with combined effects of temperature and precipitation during exposure to different air masses. Suggestions are made for improving snow cover observations to further investigate these issues.", "pred_label": "__label__POS", "pred_score_pos": 0.5337275266647339}
{"content": "Nairobi, Kajiado and Mombasa top the list of counties with the highest value of distressed property sales according to data from Kenya’s second biggest mortgage lender, Housing Finance. Data from the mortgage lender’s recent bold auction revealed 68 distressed properties in Nairobi, including one commercial property. The properties were valued at over KES 800m.\nKajiado had 11 distressed properties valued at about KES 150 million while Mombasa had 25 distressed properties valued at KES 100 million.\nAn analysis of Housing Finance’s recent bold auction campaign shows that the distressed assets under sale were scattered over 8 counties with a distressed sale value of about KES 1.23 billion. The mortgage lender recently suffered a court case that awarded KES 1.2 billion to a family following a botched property auction.\nHousing Finance has the highest non-performing mortgages in the market with a value of KES 7.66 billion (16% of mortgage portfolio) compared to Kenya Commercial Bank with KES 4.73 billion (7% of mortgage portfolio), according to a recent Centum research.\nThe research states that the auction campaign is part of the lender’s wider strategy to clean up its non-performing mortgage book in readiness for the aggressive move to the affordable housing segment and is not indicative of widespread distress in the real estate sector.\nAccording to Knight Frank’s latest Prime Global Cities Index, the rising number of distressed properties in Nairobi has also affected prime residential values significantly, with lenders intensifying efforts to recover non-performing loans through sale of collateral.", "pred_label": "__label__POS", "pred_score_pos": 0.7198618054389954}
{"content": "Taking the Hydrogen Council’s vision for hydrogen to the next level, the study entitled\nHydrogen, Scaling up outlines a comprehensive and quantified roadmap to scale deployment and its enabling impact on the energy transition. Developed with support from McKinsey and launched as global leaders gathered at COP 23 in Bonn, this report, presents the first comprehensive vision of the long-term potential of hydrogen and a roadmap for deployment. This ambitious yet realistic approach would deliver deep decarbonization of transport, industry, and buildings, and enable a renewable energy production and distribution system. To realize this vision, investors, industry, and government will need to ramp up and coordinate their efforts. Click here for the Press release Our vision: The hydrogen economy in 2050\nAchieving the hydrogen vision would create significant benefits for the energy system, the environment, and businesses around the world. It would avoid 6 Gt of CO2 emissions, create a $2.5 trillion market for hydrogen and fuel cell equipment, and provide sustainable employment for more than 30 million people.", "pred_label": "__label__POS", "pred_score_pos": 0.658928632736206}
{"content": "JoAnna Villone\nWP-07\nThis paper explores the complex processes and discourses in the construction of identity among Mexican Americans in St. Paul, Minnesota during the post-war period of 1945-1960. The construction of ethnicity within a group arises out a complex interaction between external and internal influences. It results of the tension between social and political contexts, arising from the desire of the group to maintain cultural traditions within a society that requires a certain degree of conformity from immigrants. The pressure to conform to post-war Minnesota society significantly affected Mexican-Americans in St. Paul who did not desire to surrender their cultural traditions and values and constantly sought to define their distinctiveness. The formation of ethnic identity was a process of interaction between the White communities’ definition of the Mexican American community and how they envisioned Mexican Americans would conform to American political, social, and economic institutions, as well as, Mexican American own construction of ethnicity. According to the author, the annual Independence Day celebrations played a crucial role in the construction of the Mexican American identity. It is an event that was assimilationist but also resistant to assimilation, reactive to larger social trends but also assertive and formative. The celebrations reflect the incredibly complex processes involved in “becoming Mexican American.”", "pred_label": "__label__POS", "pred_score_pos": 0.8522630333900452}
{"content": "Today in History, June 30, 1906:\nThe Federal Meat Inspection Act is passed by Congress.\nAfter Upton Sinclair had published “The Jungle” about Chicago’s corrupt meat packing industry, President Theodore Roosevelt sent representatives to investigate the industry.\nDespite the Chicago industry’s efforts to hinder the investigation, the investigators uncovered horrible practices. TR respected his investigator’s findings, and Congress acted to protect the public.\nThe USDA was born, and healthy meat processing practices were enforced. It may seem a mundane issue, but where would the health of our children be without these actions?", "pred_label": "__label__POS", "pred_score_pos": 0.9179108142852783}
{"content": "Jobless claims for the past week were lower than economists had predicted as workers begin returning to their jobs, data from the Labor Department shows.\nThe total number for jobless claims for the week ending in July 4 was 1.3 million, according to the Labor Department data, which is 99,000 fewer claims than the previous week.\nContinuing claims dropped 698,000 from a week ago to 18 million after the previous week’s 530,000 drop, the outlet reported.\nUnemployment Insurance Weekly Claims\nInitial claims were 1,314,000 for the week ending 7/4 (-99,000).\nInsured unemployment was 18,062,000 for the week ending 6/27 (-698,000).https://t.co/ys7Eg5LKAW\n— US Labor Department (@USDOL) July 9, 2020\nThe week ending in July 4 marked the 15th consecutive week that initial claims were above 1 million, CNBC reported, and Pandemic Unemployment Assistance program claims increased by 42,000 from a week ago, totaling 1.039 million.\nDespite the better than expected numbers, this marked the 15th consecutive week that initial claims totaled above 1 million.\nNews of the weekly jobless claims follows June jobs report numbers showing that the U.S. added 4.8 million jobs in June, while the unemployment declined to 11.1 percent.\nThese numbers mark the second month of both increasing jobs and dropping unemployment since the country lost a record 20.5 million jobs due to the coronavirus pandemic closures.\nMay’s unemployment rate had declined by 1.4 percentage points from April’s 14.7 percent, which was the highest unemployment rate since at least 1948.\n“These improvements in the labor market reflected the continued resumption of economic activity that had been curtailed in March and April due to the coronavirus (COVID-19) pandemic and efforts to contain it,” the report said.\n“In June, employment in leisure and hospitality rose sharply.\n“Notable job gains also occurred in retail trade, education and health services, other services, manufacturing, and professional and business services.”\nAuthor: Mary Margaret Olohan Source: Western Journal: Weekly Jobless Claims Drop Below Expert Expectations", "pred_label": "__label__POS", "pred_score_pos": 0.8997396230697632}
{"content": "Drain covers, drain protectors and sediment traps keep spills contained on site and prevent them entering stormwater drains or waterways. Store near drains to deploy quickly in the event of a spill.\nThe early stages of a spill clean up are the most critical. These protectors and covers are an excellent, low-cost preventative solution to help you avoid costly fines associated with unauthorised discharge violations.\nThese protective and preventative products are available in a variety of styles, sizes and materials. They are designed and manufactured in Australia.\nChoose from gel-filled, malleable covers, water-filled protectors, flexible urethane drain protector or drain wardens with hydrocarbon absorbent pillows for additional stormwater drain protection.\nUse this stormwater drain filter to prevent solids, silt and hydrocarbons entering waterways via...View\nUse gel-weighted drain covers to prevent spills from entering stormwater drains and traps. These...View\nThese reusable, PVC water filled drain covers can be quickly filled with a standard...View\nUse these urethane drain protector to create a tight seal over drains and prevent spills...View\nThis sediment trap is a non-absorbent, permeable barrier to trap and prevent solids and...View\nUse this 1.2m silt sock nico bag to prevent solids, coarse silt and sand from entering...View", "pred_label": "__label__POS", "pred_score_pos": 0.9964558482170105}
{"content": "What Is a Homeowners Association Fee?\nA homeowners association fee (HOA fee) is an amount of money that must be paid monthly by owners of certain types of residential properties, and HOAs collect these fees to assist with maintaining and improving properties in the association. HOA fees are almost always levied on condominium owners, but they may also apply in some neighborhoods of single-family homes.\nFor condominium owners, HOA fees typically cover the costs of maintaining the building's common areas, such as lobbies, patios, landscaping, swimming pools, and elevators. In many cases, the fees cover some common utilities, such as water/sewer fees and garbage disposal. The association may also levy special assessments from time to time if its reserve funds are not sufficient to cover a major repair, such as a new elevator or new roof. Note that some properties may assess both condo fees and HOA fees.\nHOA fees can also apply to single-family houses in certain neighborhoods, particularly if there are common amenities such as tennis courts, a community clubhouse, or neighborhood parks to maintain.\nUnderstanding Homeowners Association Fees What Do HOAs Do?\nIn addition to taking care of maintenance and repair issues, HOAs also create rules related to parking or the use of common areas. In neighborhoods of single-family homes, the HOA may create rules on how often members can paint their houses, which types of fences they may have, how they must maintain their landscaping or related issues.\nKey Takeaways Homeowners association (HOA) fees are the monthly dues homeowners associations collect. Generally, HOA fees are used to pay for amenities, property maintenance, and repairs. HOA fees are standard for most purchased condominiums, apartments, and planned communities, though some neighborhoods that consist of single-family homes also have HOA fees. What Happens If Someone Doesn't Pay HOA Fees?\nIf an owner of property governed by an HOA does not pay the required monthly or annual fees as well as any special assessments, the HOA can take action against the delinquent homeowner.\nThe actions depend on the contract between the HOA and the homeowner. Some contracts dictate that the HOA can charge late fees to the homeowner, while others allow the HOA to initiate a lawsuit, place a lien on the property, or foreclose on the owner's property to collect the delinquent payments.\nIf a member fails to remit payment to the HOA, it affects the other members of the community. Common areas may suffer due to lack of funds, or other members may be assessed special fees to cover maintenance costs or other expenses.\nHow Much Are HOA Fees?\nHOA fees vary drastically, but some estimates claim these fees are between $100 and $700 per month, with roughly $200 as an average. However, fees vary based on what the HOA provides. Generally, the more services and amenities, the higher the fees. In some cases, owners face higher fees if the reserve fund is not managed correctly.\nBecause of that, a potential homeowner should investigate the efficacy of a particular HOA before agreeing to buy a home in that community. Additionally, the buyer should add the cost of the fee into their prospective budget when determining whether or not they can afford a property.", "pred_label": "__label__POS", "pred_score_pos": 0.8589948415756226}
{"content": "Optimising CAR-T efficacy in pancreatic cancer with bioengineered scaffolds and immune agonists lead supervisor: Prof Eric o'neill, department of oncology lead supervisor: Prof Eric o'neill, department of oncology Co-supervisor: Prof Hua Ye, Department of Engineering Science Commercial partner: Oxford BioMedica, Oxford\nCancer stem cells (CSCs) can drive tumorigenesis as founder elements or through malignant\ncells that gain stem cell traits. CSCs are defined as slowly replicating cells, where bulk tumour growth arises from non-CSCs. Therapeutic strategies target fast-replicating cells in bulk tumour, as more quiescent CSCs avoid targeting and contribute to recurrence and metastatic spread by repopulating the non-CSC compartment. Although challenging, due microenvironmental factors and tumour plasticity between CSC and non-CSCs, targeting CSCs is critical in the search for curative cancer treatments. The oncofetal tumor-associated antigen 5T4 (TBGP) has been identified as a CSC marker in several malignancies. OXB have developed immunotherapies targeting 5T4 including a Vaccinia-based vaccine (Trovax) and 5T4-directed chimeric antigen receptor T-cells (CAR-T) (OXB-302) with positive responses in clinical trials.\nAlthough promising, Vaccine and CAR-T cell therapies are less effective in solid tumours due to\ninefficient tumour targeting, the immunosuppressive microenvironment; and tumour heterogeneity/plasticity. Implantable biopolymer devices can deliver vaccines or CAR-T cells directly to the surfaces of solid tumours (e.g. pancreatic cancer and melanoma), and are more effective in tumour targeting than systemic delivery. We aim to adapt this technology to implant biopolymer scaffolds to target 5T4 expressing cells in orthotopic human tumours engrafted in immunocompromised mice. Additionally, combination of CAR-T strategies with the agonists of the STimulator of IFN Genes (STING) pathway (e.g. cyclic di-GMP) can lead to dramatic tumour regression. This is achieved though stimulation of antigens not recognized by the adoptively transferred lymphocytes that could target heterogeneous tumours or CSC and non-CSC compartments.\nThus, we propose a project to understand the role of 5T4 in CSCs, investigate bioengineering\nscaffold devices that concentrate and localise 5T4-target therapies in solid tumours and combine these with STING agonists to protect against the emergence of escape variants in vivo. We aim to explore the feasibility of these approaches in vivo in mice and in human tissue samples. The candidate will gain experience in cell and tumour biology, bioengineering of scaffolds and in the design, construction and deployment of CAR-T cells in these experimental models.", "pred_label": "__label__POS", "pred_score_pos": 0.9910160303115845}
{"content": "Map Unavailable Date/Time Date(s) - 10/29/2020 12:00 PM - 1:30 PM Location Remote via Webinar Categories Session One – Racial Disparities in the Criminal Justice System, Collateral Consequences and Barriers to Second Chances\nBlack Americans are more likely than white Americans to be arrested. Once arrested, they are more likely to be convicted. Once convicted, they are more likely to experience lengthy prison sentences. Moreover, there are drastic racial disparities in the enforcement of laws, judiciary proceedings and treatment within and beyond the criminal justice system. When an individual is arrested or convicted of a crime, they face a vast web of laws and policies, including court-imposed fees and fines. For many who are low income, these function as permanent punishments – barriers that limit human rights and restrict access to crucial resources needed to re-build lives.\nPresenters in this session will discuss the collateral consequences of criminal justice system involvement, and the disproportionate impact on communities of color. They will also assist as we begin to explore how the legal community can advocate for change, including through policy efforts and by providing direct service to low income individuals seeking expungement of criminal records (see session below on criminal expungement basics).\nSPEAKERS", "pred_label": "__label__POS", "pred_score_pos": 0.914955198764801}
{"content": "Research has documented that outstanding leaders take time to reflect. Their success depends on the ability to access their unique perspective and bring it to their decisions and sense-making every day.\nNecessary cookies are absolutely essential for the website to function properly. This category only includes cookies that ensures basic functionalities and security features of the website. These cookies do not store any personal information.\nAny cookies that may not be particularly necessary for the website to function and is used specifically to collect user personal data via analytics, ads, other embedded contents are termed as non-necessary cookies. It is mandatory to procure user consent prior to running these cookies on your website.", "pred_label": "__label__POS", "pred_score_pos": 0.999602735042572}
{"content": "Create an Account - Increase your productivity, customize your experience, and engage in information you care about.\nThe Alameda-Contra Costa Transit District (AC Transit) continues to provide bus service to healthcare, resources, and employment, during the ongoing novel coronavirus (COVID-19) pandemic. While service is deemed essential transit, AC Transit is doing its part to ensure that everyone is practicing social distancing to stem-the-tide of COVID-19 transmission.\nIn addition to the Centers for Disease Control and Prevention (CDC) guidance to establish Rear Door Boarding and restrict a six-foot space around the operator’s compartment, we are now minimizing the number of riders on each bus. This practice will remain in place until further notice.\nAs a result, AC Transit directly appeals to riders and communities, to partner with them in maintaining the following passenger thresholds:\nOnce the on board count nears or reaches the new COVID-19 passenger thresholds, the operator may bypass stops. For waiting riders, the external head-sign will convert to “Drop-Off Only,” alerting that the bus will not stop. For riders on board, the operator will continue to recognize requests to exit. AC Transit riders may experience trip delays and are asked to plan accordingly. It is important to note, on board safety is paramount and AC Transit sincerely apologizes for any inconvenience.\nIn addition to social distancing, AC Transit strongly encourages riders to follow CDC guidelines to wear a cloth face mask on board, covering the nose and mouth, effective immediately. Riders will continue to experience their bus operator wearing personal protective equipment (PPE) including gloves, eyewear, and masks. Riders should avoid interactions with the bus operator.\nWhile they augment safety practices, AC Transit reminds riders to travel for essential trips only. When bus transit is necessary, kindly avoid buses displaying Drop-Off Only, always practice proper hand-washing, and strictly observe coughing and sneezing etiquette – by using one’s elbow or disposable tissue.\nFor the latest COVID-19 service updates and trip planning, please visit www.actransit.org.", "pred_label": "__label__POS", "pred_score_pos": 0.9664937853813171}
{"content": "A federal judge has granted the Federal Trade Commission’s request for a preliminary injunction against two people and their companies for allegedly tricking small commercial trucking businesses into paying them for federal and state motor carrier registrations by impersonating government transportation agencies, such as the U.S. Department of Transportation (USDOT).\nConsumers who own and operate certain types of commercial vehicles must register annually with the Unified Carrier Registration (UCR) system or their state government and pay a fee based on their fleet size. Some of these small businesses also must file a Motor Carrier Identification Report every two years, which can be done at no charge on the Federal Motor Carrier Safety Administration website.\nAccording to the FTC’s complaint, the defendants have taken in more than $19 million from thousands of small businesses by sending misleading robocalls, emails, and text messages that create and reinforce the false impression that they are, or are affiliated with, the USDOT, the UCR system, or another government agency. As noted in the FTC’s complaint, the defendants used official-sounding names, official-looking websites, warnings of $1,000 in civil penalties or fines for non-compliance, and threats of imminent law enforcement to trick consumers into using their registration services instead of using official government website services.\nAccording to the complaint, the defendants deceptively disclosed the total amount charged, without telling consumers the cost included the defendants’ service fees that ranged from $25 to $550 or more. The FTC also alleges that many consumers who paid the defendants’ UCR fees were automatically enrolled, without their knowledge or consent, in “SafeRenew,” the defendants’ annual renewal program for UCR fees.\nDefendants James P. Lamb, Uliana Bogash, DOTAuthority.com Inc., DOTFilings.com Inc., Excelsior Enterprises International Inc. and JPL Enterprises International Inc. are charged with violating the FTC Act and the Restore Online Shoppers Confidence Act.\nThe Commission vote authorizing the staff to file the complaint was 3-0. It was filed in the U.S. District Court for the Southern District of Florida. The court entered a preliminary injunction against the defendants on September 29, 2016.", "pred_label": "__label__POS", "pred_score_pos": 0.7160231471061707}
{"content": "I have developed this class in response to what seems to be a growing number of individuals who wish to actively manage their physical health conditions but struggle to participate fully in mixed group classes due to specific limitations.\nThis physio-led Pilates class will provide a safe space to build confidence in movement and exercise without a feeling of overwhelm, or exclusion that can sometimes occur in mixed ability groups.\nIf you are recovering from illness or injury, or managing a longer term condition such as arthritis, or simply wish to participate in gentle, encouraging movement class without pressure to “achieve” more reps, more “burn”. If you are unsure about what your body is capable of following injury or in light of ongoing conditions and feel this is a barrier to you moving forward with positive health goals, this is the class for you.\nTo register your interest or find out more – contact me today.", "pred_label": "__label__POS", "pred_score_pos": 0.7901943922042847}
{"content": "Our Pilgrim Status Our Pilgrim Status Warren E. Berkley\nIn order to be a Christian, with persuasive power and reverence, you must personally come to terms with your pilgrim status. This earth is not our permanent home. (In fact, this earth is not anyone’s permanent home, see 2 Pet. 3:10-13). Nobody will live on the earth forever because the earth will not last forever. Peter puts it simply:\n“…both the earth and the works that are in it will be burned up!”\nI bring this up because if we don’t get this, we cannot effectively learn or apply the teachings of Christ in the New Testament. We must not just play with the idea intellectually, we must personally embrace it. We are pilgrims.\n“Beloved, I beg you as sojourners and pilgrims, abstain from fleshly lusts which war against the soul, having your conduct honorable among the Gentiles, that when they speak against you as evildoers, they may, by your good works which they observe, glorify God in the day of visitation,” (1 Pet. 2:11,12).\nYou cannot consistently abstain from fleshly lusts until you recognize your pilgrim status. You cannot participate in the defeat of those things that war against the soul, if you are holding to this earth as your home. You cannot wholeheartedly engage in honorable conduct “among the Gentiles,” until your attachment to this world is put in true perspective. You cannot lead people to glorify God in the day of visitation, while living in denial of your pilgrim status.\nAs Christians, we are more related to heaven than earth. If we don’t get that, we cannot get the rest of it right. May our confession be: “I am a stranger in the earth; do not hide Your commandments from me,” (Psa. 119:19).", "pred_label": "__label__POS", "pred_score_pos": 0.7682752013206482}
{"content": "Nothing is permanent, that includes the pipes inside your home. As time goes on, pipes gradually corrode, rust and decay. Eventually, you get leaks or worse a flood. This could potentially bring water and even raw sewage into your home or business causing thousands of dollars in damage.\nWater Pipe Replacement Replacing / repiping an entire home is a big job and unless you're planning a remodel you don't want to do it early. That's why Green Tech Plumbing is here to help you assess the situation and your available options. We'll work with you to develop a plan that matches your property's needs and your budget. Water repiping is a complicated job but we've got your back. Call Green Tech Plumbing to schedule a free estimate on your water pipe replacement project How Long Do Pipes Last? The type of plumbing installed on your property determines how long you can expect it to last. This information can be found by examing the pipes or by checking your home inspection report from the time of purchase.\nSupply Pipes These are the pipes bringing water into your home. They are under constant pressure and most likely to leak.\nBrass Pipes - 80 to 100 years.\nCopper Pipes - 70 to 80 years. Galvanized steel - 80 to 100 years. Lead and Polybutylene - Remove ASAP Drain Pipes Cast iron - 80 - 100 Years Polyvinyl chloride (PVC) - 25-40 Years\nThese are just guidelines. The actual time will vary by environmental conditions and maintenance schedules. For example, if your water has a high mineral content, your pipes are more likely to corrode. If your pipes are starting to age, call Green Tech Plumbing for a free plumbing inspection.\nWhen To Repipe / Replace Lines? Older Home - If your house is over 50 years old and using galvanized steel pipes. Or if your plumbing is a network of different materials and is using non-standard routing methods. Leaks - If you're dealing with frequent leaks from multiple locations. As water pipes age the materials used to weld the joints can start to fail. Replacing the water supply pipes now could save you money on future repair costs. Low Water Pressure - If the water pressure is continually dropping and is accompanied by reddish-brown water coming out of the tap. Sometimes the water may only be brown initially and then turn clear. This is a sign that the old pipes have accumulated minerals on the interior and reducing water flow. Slab Or Pinhole Leaks - Pipes inside your foundation can leak and cause parts of your home to appear damp or wet. This typically occurs in older homes when the pipes in the foundation corrode and start to fail. They may not be noticeable at first but over time they can cause some serious damage. Water Bill Going Up - If your water bill is going up without a good reason it may be your pipes. If you turn off the water to your home and the meter continues to run then you've got a leak in your water system.", "pred_label": "__label__POS", "pred_score_pos": 0.5645283460617065}
{"content": "Abstract\nPlatelets play roles in malignancy, wound healing, and immunity. Nevertheless, their significance in postoperative outcomes is not established. This is a retrospective cohort study of 100,795 patients undergoing cancer surgery in 2010 and 2014 in >500 hospitals. Patients were stratified into five groups based on preoperative platelet counts. Multivariable logistic regression was used to determine the risk of 30-day mortality, morbidities, readmission, and prolonged hospitalization using the mid-normal group as a reference. We adjusted for demographic variables, comorbidities, and operation complexity. In the 2014 cohort, multivariable analysis showed that mortality was higher in patients with thrombocytopenia (OR 1.49, 95% CI [1.23–1.81]), high-normal platelets (OR 1.29, [1.06–1.55]), and thrombocytosis (OR 1.78, [1.45–2.19]). Composite postoperative morbidity followed a similar trend with thrombocytopenia (OR 1.34, [1.25–1.43]), high-normal counts (OR 1.41, [1.33–1.49]), and thrombocytosis (OR 2.20, [2.05–2.36]). Concordantly, the risks of prolonged hospitalization and 30-day readmission followed the same pattern. These results were validated in a large colon cancer cohort from the 2010 database. In conclusion, platelet count is a prognostic indicator in cancer surgeries. This could be related to the role of platelets in wound healing and immunity on one hand, and propagating malignancy on the other.\nKeywords Morbidity mortality oncology thrombocytes ASJC Scopus subject areas Hematology", "pred_label": "__label__POS", "pred_score_pos": 0.7769560217857361}
{"content": "The identification of a critical junction in the brain could lead to new treatments for Alzheimer's disease, according to a recent study. Researchers have found an area considered to be the doorway to the hippocampus, which is key for transforming daily experiences into lasting memories. The hippocampus is the source of the learning capacity in humans, allowing people to remember vital information. It is believed that by stimulating the entorhinal cortex with electrical impulses memory can be strengthened, providing a solution for symptoms experienced by those with Alzheimer's disease. The discovery was made when observing seven epilepsy patients who had electrodes implanted in their brain to locate the origin of their seizures. When monitoring the electrodes it was found that when nerve fibres where stimulated in patients, landmarks could be identified. A spokesperson from the Alzheimer's Society commented: \"We still don't know exactly what happens in the brains of people with Alzheimer's to cause symptoms such as memory problems. \"Research which could broaden our knowledge of this is therefore essential.\" However, the Alzheimer's Society warns that more research is needed in a larger and more targeted study before scientists can begin to develop an effective treatment. Find out more about Alzheimer's disease care at Barchester homes.", "pred_label": "__label__POS", "pred_score_pos": 0.5814986228942871}
{"content": "Boundaries are everywhere: between sectors, geographies, generations, backgrounds and beliefs. Chicago is replete with boundaries that are old, and create fear and uncertainty, even among those courageous enough to approach, touch and attempt to transcend them.\nChicago will not reach its true potential if our city does not break through these boundaries by convening the next generation of leaders to establish diverse relationships, facilitate crucial conversations and collaborate around future solutions.\nThe Chicago200 initiative can transcend these boundaries.\nChicago200 is an annual leadership program that convenes young diverse leaders from across the Chicago region to address the question,\n“What will we make our city known for by its 200th birthday in 2037?”\nChicago 200 will connect individuals of different economic status—our North Side and West Side residents with our South Side and Downtown residents, our young people with our established adults—all to chart the course for a more equitable Chicago by 2037.\nDuring the inaugural program in April 2019, participants will meet with city and neighborhood leaders to brainstorm, test, refine and present their visions for the city over four days. They will investigate key issues, hold difficult conversations and collaborate around tangible solutions for Chicago.\nThen,\nOn the Table 2019 will accelerate the momentum. As a follow up to Chicago200, participants will host an On the Table discussion focused on how to implement solutions emerging from Chicago200.\nBeyond 2019, the goal is that a diverse alumni group of 2,000 leaders will emerge from the program over the next ten years. As advisors to established leaders in the city, these young leaders will express their vision for the city and help shape Chicago’s future. By 2037, ten big ideas will have emerged, which these leaders will help make a reality.\nThe 2019 inaugural pilot of Chicago200 is supported by the Trust in partnership with Common Purpose, with support from Chicago Public Media, University of Chicago, The John D. and Catherine T. MacArthur Foundation, City Colleges of Chicago, Chicago Votes, Northern Trust, 1871, Civitas Child Law Center of Loyola University and Window to the World Communications, Inc. (WWCI), parent organization of WTTW and WFMT.", "pred_label": "__label__POS", "pred_score_pos": 0.7048331499099731}
{"content": "Executor or Personal Representative\nAn executor (also called\npersonal representative or administrator in some states) is the person who will be in charge of your probate. He or she will: gather your assets; handle the sale of your assets, if necessary; prepare an inventory; hire an attorney; and distribute the property.\nThis should be a person you trust, and if it is, state in your will that no bond will be required to be posted by him or her. Otherwise, the court will require that a surety bond be paid for by your estate to guarantee that the person is honest. It is best to appoint a resident of your state as executor, because a bond may be required of a nonresident even if your will waives it.\nSome individuals select two people to handle the estate to avoid jealousy, or to have them check on each other's honesty. However, this is not always a good idea. It makes double work in getting the papers signed, and there can be problems if they cannot agree on something.\nA bank can serve as executor of your estate, but their fees are usually high. Remember, the person handling your estate is usually entitled to some compensation. Some states specify a percentage, while others allow a reasonable hourly fee. A family member will often waive the fee. If there is a lot of work involved, the executor may request the fee, or other family members may insist that he or she take one. You can insist in your will that your executor or personal representative be paid a fee.\nIn many states, an executor or personal representative cannot sell your real estate without approval by the court. If you trust your executor, you can avoid the expense and delay of this by giving him or her the power to do so without court approval.", "pred_label": "__label__POS", "pred_score_pos": 0.713426947593689}
{"content": "The Four Quadrants of Learning: Contextualizing the Language of Instruction for Students with Disabilities By Marissa Desiree Pardo\nThis issue of\nNASET’s Classroom Management series was written by Marissa Desiree Pardo. The following case being studied will focus on Eradio, a seventh-grade student who is Deaf and hard in Hearing (DHH). He is struggling in his Social Studies classroom at Palm Tree Middle School. As a result of this study, a range of contextual supports and cognitive involvement will be examined. Cummins’ four quadrants of language learning will be explained including quadrant one, cognitively undemanding and context embedded, quadrant two, context embedded and cognitively demanding, quadrant three, cognitively demanding and context reduced, and quadrant four, context reduced and cognitively demanding (Cummins, 1995). This study will identify at least three activities per quadrant that Eradio can benefit from participating in that fall within the criteria of each quadrant. To Access this Article\nTo access the full issue of this month's Classroom Management Series, NASET members should login to view and or download a PDF file version.", "pred_label": "__label__POS", "pred_score_pos": 0.939430832862854}
{"content": "Research Alert\nNewswise — The narratives of patients and families with spinal cord injury tell the story of how people make sense of the injury and the rehab experience. Reading these stories provides insight for the rehabilitation nurse to better understand the illness experience from the patient and family perspective– which in turn – can help identify nursing interventions to assist in those experiences. Read\nConstructing Recovery Narratives: Experiences and Expectations Following SCI.\nAbstract\nPurpose\nThis study aimed to explore how married individuals construct narratives following spinal cord injury (SCI).\nDesign\nProspective qualitative study.\nMethods\nEighteen married people with SCI were recruited during inpatient hospitalization. In-depth interviews were conducted at approximately 1, 4, and 7 months post-SCI. Interviews were analyzed using thematic analysis.\nFindings\nParticipants constructed three primary narrative types (optimistic, anxious, and stability) about their trajectories following SCI, focusing on their expectations about recovery and their past and current experiences with their spouse, peers, and health professionals. These narrative types are the foundation for understanding how people make sense of the rehabilitation experience in relation to others.\nConclusions\nFindings provide an initial understanding of how expectations of life with SCI as well as social interactions in the healthcare setting influence experiences of injury and recovery.\nClinical Relevance\nFindings can inform future interventions during SCI rehabilitation to ease transitions and decrease anxiety following SCI.", "pred_label": "__label__POS", "pred_score_pos": 0.9840100407600403}
{"content": "Approximately 6,000 eviction filings occur in Hennepin County each year, and about 90% of alleviction judgements are due to nonpayment of rent. Eviction results in forced displacement,contributing to instability within neighborhoods and potentially harmful effects for children,families, and individuals. Despite the growing number of studies on the subject, the link betweencounty service use, an eviction filing or judgement, and shelter entry in Hennepin County wasunsubstantiated. Our report aims to fill this gap. At the request of Hennepin County, we soughtto demonstrate the link between evictions and homelessness as well as identify barriers in theeviction prevention process.Our research team conducted a mixed-method analysis using quantitative and qualitative data. Inour qualitative research, we interviewed individuals in organizations that provide services andmonetary aid aimed at preventing eviction. We employed snowball sampling to speak with 19staff members at different governmental and nonprofit providers across the county, usingsemi-structured interviews to catalogue their experiences and perspectives.\nProfessional paper for the fulfillment of the Master of Public Policy degree.\nSuggested Citation\nHoldener, Andee; Nelson, Jessica; Quint, Lydia; Rea, Nicholas; Svitavsky, Katherine; Uhrich, Maria; Whelan, Nicole; Zanoni, Caitlin.(2018).Eviction and Homelessness in Hennepin County.Retrieved from the University of Minnesota Digital Conservancy,http://hdl.handle.net/11299/206597.\nContent distributed via the University of Minnesota's Digital Conservancy may be subject to additional license and use restrictions applied by the depositor.", "pred_label": "__label__POS", "pred_score_pos": 0.9380250573158264}
{"content": "Genome-wide association studies (GWAS) have identified over 100 risk loci for schizophrenia, but the causal mechanisms remain largely unknown. We performed a transcriptome-wide association study (TWAS) integrating a schizophrenia GWAS of 79,845 individuals from the Psychiatric Genomics Consortium with expression data from brain, blood, and adipose tissues across 3,693 primarily control individuals. We identified 157 TWAS-significant genes, of which 35 did not overlap a known GWAS locus. Of these 157 genes, 42 were associated with specific chromatin features measured in independent samples, thus highlighting potential regulatory targets for follow-up. Suppression of one identified susceptibility gene, mapk3, in zebrafish showed a significant effect on neurodevelopmental phenotypes. Expression and splicing from the brain captured most of the TWAS effect across all genes. This large-scale connection of associations to target genes, tissues, and regulatory features is an essential step in moving toward a mechanistic understanding of GWAS.", "pred_label": "__label__POS", "pred_score_pos": 0.9997536540031433}
{"content": "MD Bryan Hindle attended the monthly branch meeting of IOSH (Institution of Occupational Safety and Health), today. Every month these meetings feature a few hours of worthwhile safety training and this month, mental health was on the agenda. This event was organised by IOSH Yorkshire’s members and included two professional presentations.\nDr Jo Yarker presents her research to IOSH members on sustainable return to work.\nDr Jo Yarker has been examining the resources people use when they return to work. She presented data from interviews conducted with 38 returning employees and managers who have supported return to work. Putting this in context; in the UK alone, stress, anxiety or depression accounts for 44% of all ill-health related cases and 57% of all working days lost to ill-health in 2017-2018 (HSE, 2018). Returning to work following sickness absence can be challenging; too many people struggle to return, and many subsequently relapse and take further absences.\nThe research suggests that supporting an employee to strengthen their IGLOO – their Individual, Group, Line Manager, Organisation and Overarching resources – can help them to return to, and stay in work. This was a fascinating session and provoked some good question and answers from the floor.\nVictoria Filed delivered a really useful and practical session. Her presentation was packed with essential links to on-line mental health resources. Most of these were for health and safety professionals, however, there were others, which could be used to help employees who may have concerns, or be suffering from stress and anxiety. As a result this was also very well received by delegates and once more, there were lots of questions from members.\nWhat has all this to do with Brick-Tie Preservation? Everyone has a right to be respected at work, be free from anxiety and to feel valued. We believe that the health and well-being of all of our team impacts the service we provide for clients. Therefore, our people can enjoy their work and look after our customers with a smile. It is one reason why we take time-out to attend these meetings and bring the best ideas back home, for everyone’s benefit.\nYou can read about some of the work we have been doing to help our employees stay mentally safe and healthy at work here\njobs - Wall Tie Survey - Health and Safety - damp diagnosis - NVQ - CPD - Wall Tie Corrosion - woodworm - bryan hindle - Staff Training - mould - DryRod - Cintec Anchors - wet rot - structural repairs - mould growth - training - charity - condensation - timber survey - Helifix - damp survey - DryZone - damp - Vandex - Thermography - customer service - Dry Rot - Chemical damp proofing - Oldroyd Green - CSRT - Timber Infestation - Basement Waterproofing - PCA", "pred_label": "__label__POS", "pred_score_pos": 0.6109681129455566}
{"content": "CYBRARY RESEARCH STUDY\nHybrid Skills in Cybersecurity: Educating the Workforce to Advance the Evolution of Future Roles\nPhilip H. Kulp | Nikki E. Robinson | Travis D. Howard\nCybrary Fellowship Research, August 2020\nCYBRARY RESEARCH STUDY\nPhilip H. Kulp | Nikki E. Robinson | Travis D. Howard\nCybrary Fellowship Research, August 2020\nCybersecurity roles are transitioning to hybrid jobs composed of technical and soft skills that require practitioners to integrate varying competencies. Practitioners must understand that learning is a journey and not a goal because technology changes so rapidly that new skills must be continuously acquired. The purpose of this study was to survey Cybersecurity and Non-cyber IT professionals to identify the awareness and practice of Hybrid Skills. The analysis of the data focused on understanding if Cybersecurity professionals are currently practicing Hybrid Skills and identify the source of learning. 85% of the participants responded that they relied on self-study to learn new skills, while only 30% of the participants identified a university as the source of continuing knowledge.\nThe survey collected data from Cybersecurity and Non-cyber IT professionals to compare responses and identify differences across the industries. The survey responses for respondents’ understanding of Hybrid Skills needed for their jobs suggest that Cybersecurity respondents outperform the Non-cyber IT respondents. The respondents were then asked if they review job postings to identify trends in their roles. The results again favored the Cybersecurity respondents. Finally, the responses from Cyber and Non-cyber IT professionals were compared to examine the active implementation of Hybrid Skills in their current roles.\nHigh-level observations from the survey:\nThe survey proved to be an overwhelming success with over 1800 people responding from the Cybersecurity and Non- cyber IT roles. Participants reported their age, gender, and the highest level of education achieved. Respondents to the survey also self-reported the title of their current position.\nPractitioners must understand that learning is a journey and not a goal because technology changes so rapidly that new skills must be continuously acquired. Automation has been predicted to replace jobs for many years; instead, robots replace tasks and not whole jobs\n[5]. Workers must contend with multiple factors over a career which could detract from their marketability. Employers must understand those job seekers may also desire careers that are not only challenging but also fulfilling. New professionals entering the workforce are not always looking for the highest paying job; a meaningful job is still attractive. Taking into account the broad aspects of a lifetime of learning, Cybersecurity professionals must create a plan to stay relevant in the job market by monitoring trends and adapting to changes while following a meaningful career path.\nA combined MITx and Harvardx report on edX identified 66% of registrants as having at least a bachelor’s degree\n[7]. The demographic information portends workers’ understanding of the need for further training in specific topics after graduating from a traditional institution. Coding bootcamps and other modular learning opportunities can be leveraged to gain particular skills needed to enhance a career or maintain an existing role. Other forms of modular learning are accessible through Massive Open Online Courses (MOOC) and online learning platforms such as Cybrary. Self-styled learning requires organizational skills and learning from mostly asynchronous material, which may not suit every student. Students must also discover the best methods they need for learning. Students must select the training which will provide a benefit to their current role or position them to meet the requirements of a future job.\nUC Berkley described data science as the “biggest minor” in the near future, which will prepare students for performing work in other areas of their careers\n[2]. IT and Cybersecurity roles will require the ability to make sense of data for the business. These jobs will also require the ability to communicate with managers, team members, and engineers on other teams [1]. The jobs of the future will require Hybrid Skills composed of not only hard skills such as data science and statistics, but soft skills such as relationship building, collaboration, and emotional intelligence. The soft and hard skills used in the survey questions were based in part on top competencies Google looks for in candidates [6]. While some jobs may benefit from Hybrid Skills, others may cross functional boundaries and be compromised of skills from diverse fields.\nThe National Initiative on Cybersecurity Education (NICE) framework created a taxonomy of the terms related to the cybersecurity workforce\n[4]. While NICE attempted to create a clear distinction among cybersecurity fields, some hybrid jobs already exist, with combined Cybersecurity and Non-cyber IT roles. For example, a cybersecurity legal counsel, privacy compliance officer, or cyber threat intelligence linguist bridge the divide between the law and cybersecurity [3]. As the company’s intellectual property and business function become tied to data, cybersecurity awareness will permeate into every role in the organization; cybersecurity hybrid jobs may become the norm.\nSurvey respondents answered questions on a scale from 1 to 5. An answer of 1 represented\n, and a 5 Strongly Disagree The first question was general to see how respondents self-reported. The responses were compared to actual Hybrid Skills to identify the difference between perception and reality. Cybersecurity respondents reported an average response of 4.2. Non-cyber IT respondents reported an average of 3.9. The next question was more specific to understand how people discover the Hybrid Job skills they should be learning. Cybersecurity respondents reported an average response of 3.9. Non-cyber IT respondents reported an average of 3.5. A difference between the perceived understanding of Hybrid Skills and the discovery already appeared. Cybersecurity respondents reported an average response of 3.8. Non-cyber IT respondents reported an average of 3.6. A further divergence was identified between perceived understanding of hybrid skills and the application of Hybrid Skills in their current role.\nThe responses to the survey were evaluated according to two major themes to determine if a gap exists between the perception that Cybersecurity professionals understand Hybrid Skills and if they are practicing them:\nThe responses were compared between Cybersecurity and Non-cyber IT respondents. The comparison is needed to determine if Cybersecurity professionals are maintaining the skills required to compete in the current and future marketplace. During the compilation of the data, some interesting trends emerged regarding education levels, so further analysis was performed.\nTwo survey questions were used to measure the understanding of Hybrid Skills. The first question asked respondents, “I understand the hybrid skills needed to maintain my marketability (skills which are not core to my job).” The second was indirect and asked respondents about how they actively tracked job trends with the following questions, “I review job openings to look for trends in the market.” The table below includes the average responses to each question and the combined average per reported role.\nFor both questions, the Chi-square test of homogeneity was used to determine if an equal distribution across the sample could be identified. Cybersecurity professionals exceeded the critical value of both tests, which suggests that the responses comparing Cybersecurity and Non-cyber IT were not evenly distributed. Cybersecurity professionals overperformed the expected rate of self-reported knowledge of the Hybrid Skills needed to maintain marketability by 4.8%. Cybersecurity professionals overperformed the predicted rate by 7.8% when answering the question that they review jobs to understand trends in the market. While the responses to these questions point to encouraging signs for Cybersecurity professionals, the researcher performed additional analysis of the responses.\nThe responses were separated for each reported role, and the average was calculated. Data Scientists responded with the highest rates, followed by Cybersecurity professionals. An interesting observation was the low ranking for Executives. Upon further review, the data seems to make sense since Executives tend to stay in positions longer than IT professionals, so they would not be searching for job postings. Data Scientists had the highest response values, which is of interest since they also had the highest rate for Hybrid Skills in practice.\nNine questions in the survey were used to assess Cybersecurity professionals’ practice of Hybrid Skills compared to all other professionals in the IT industry. Some of the questions were related to technical skills such as the use of statistics, Data Science, ML, or AI. Other questions related to soft skills such as team collaboration, artistic, social, and emotional intelligence. The table below includes the averaged responses to each question and the combined average per reported role.\nFor the nine questions regarding the practice of Hybrid Skills, the same Chi-square test was used to determine if an equal distribution across the sample could be identified. Cybersecurity professionals exceeded the critical value of the test, which suggests that the responses comparing Cybersecurity and Non-cyber IT were not evenly distributed. The Cybersecurity professionals exceeded the expected value of the responses as compared to Non-cyber IT professionals.\n“What resources do you use to acquire new skills?”\nAcross all industries, 85% selected self-study, 48% selected MOOC, and 62% selected certifications. Only 30% selected universities. These results do not discount the value of higher education since universities build the foundation and structure for a lifetime of learning. The respondents high rate of self-study suggests they understand traditional education is not the end of the experience, and continuous knowledge is a requirement.\nCybersecurity and Non-cyber IT professional chose ‘None’ and ‘MOOC’ at approximately the same rate. ‘Self-study’ was chosen at similar rates, with Cybersecurity at 89% and Non-cyber IT at 85%. The two groups diverged further when selecting certifications with Cybersecurity responding at 75% and Non- cyber IT at 57%. Some differences were observed with the response for ‘University’ with Cybersecurity selecting the response 35% and Non-cyber IT at 29%.\nThe differences between the two groups may be associated with the entrance requirements into the field, either realistic or perceived. The question “How can I break into the cybersecurity field,” is encountered continuously by those already in cybersecurity. Cybersecurity professionals do not always point to universities as their source of knowledge for their job, but they responded with higher rates than the Non-cyber IT respondents. With the high response rates of 89% and 75% for self-study and certifications, respectively, cybersecurity professionals appear to understand the need for continuous learning. The need for self-study and attaining certifications may also affect the responses by Cybersecurity professionals to the question regarding how a newcomer can break into the industry.\nAfter analyzing the results of learning resources, the demographic data for education was re-visited and divided by the job role to review the differences between Cybersecurity and Non-cyber respondents.\nDr. Philip Kulp is a Cybrary Fellow and content creator on the Cybrary platform. He has been consulting in cybersecurity for over 20 years and performing other IT roles for over 25 years. In his current role as a cybersecurity architect and incident responder, he combines his passion for IT and cybersecurity to develop realistic approaches to secure the enterprise. He also serves as a secure code reviewer, independent assessor, and webapp tester. Dr. Kulp developed the NIST 800-53 and DevSecOps Fundamentals courses for Cybrary and is actively working on other classes to deliver content for the cyber community. Philip seeks opportunities to balance his cybersecurity skills between academic, technical, and compliance roles. He holds the CISSP certification and two Offensive Security certifications of OSCP and OSCE. In his educational capacity, Philip serves as a chair, committee member, and mentor for doctoral students in the Ph.D. and D.Sc. programs at Capitol Technology. He also serves as an adjunct professor at Drexel University. Dr. Kulp has authored research papers on security for medical drone security, graphing website relationships to predict website security, and the current topic of Hybrid Skills in the cybersecurity community.\n[1] Bentley University. 2016. 2016 Year of the ‘Hybrid Job’.\nhttp://www.bentley.edu/prepared/2016-jobskills.\n[2] Joyce, L. 2020. Data Science: A 21st Century Job Skill for Every Discipline.\nhttps://blog.edx.org/data-science-a-21st-century-job-skill-for-every-discipline/.\n[3] Bate, L. 2018. Cybersecurity Workforce Development: A Primer.\nhttps://www.newamerica.org/cybersecurity-initiative/reports/cybersecurity-workforce-development/.\n[4] National Institute of Standards and Technology. National Initiative for Cybersecurity Education (NICE).\nhttps://www.nist.gov/itl/applied-cybersecurity/nice.\n[5] The Economist. 2017. Lifelong Learning is Becoming an Economic Imperative.\nhttps://www.economist.com/special-report/2017/01/12/lifelong-learning-is-becoming-an-economic-imperative\n[6] Elmore, T. 2018. The Seven Top Skills Google Now Looks for in Graduates.\nhttps://www.psychologytoday.com/us/blog/artificial-maturity/201807/the-seven-top-skills-google-now-looks-in-graduates.\n[7] Ho, A.D., Reich, J., Nesterko, S.O., Seaton, D.T., Mullaney, T., Waldo, J., Chuang, I., 2014. HarvardX and MITx: The First Year of Open Online Courses, Fall 2012-Summer 2013. SSRN Journal.\nhttps://doi.org/10.2139/ssrn.2381263", "pred_label": "__label__POS", "pred_score_pos": 0.5132514238357544}
{"content": "Congress has returned to Washington, DC, to face multiple issues that could affect GNYHA members in the coming months. We prepared the attached white paper outlining our current legislative priorities, which include Medicaid disproportionate share hospital (DSH) cuts, surprise billing legislation, graduate medical education, drug pricing, and infrastructure.\nCongress’s top priority in September will be to pass a spending bill for Federal fiscal year (FY) 2020 before it begins on October 1. Congress will likely pass a short-term continuing resolution (CR) to prevent a government shutdown while negotiations on the full-year spending package continue.\nBoth long- and short-term spending bills often serve as vehicles for other legislative proposals, and GNYHA will advocate to include our priorities in any legislation that passes. Specifically, spending legislation is an appropriate vehicle to address our top priority, the delay of the Medicaid DSH cuts. It also could serve as a vehicle for legislation to address the nation’s worsening physician shortage by funding additional Medicare-reimbursed residency slots, such as the\nOpioid Workforce Act of 2019 (H.R. 3414), which recently passed the House Ways & Means Committee.\nSurprise billing legislation also remains a top priority for Congress. GNYHA’s position is that Congress should address surprise medical bills, but that any proposal that passes must not include the setting of benchmark rates. New York State’s surprise billing law is an ideal model for Congress to follow. An outline of our surprise billing principles can be found here.\nOver the summer, both the Senate Health, Education, Labor and Pensions (HELP) Committee and the House Energy & Commerce Committee passed surprise billing proposals that set benchmark rates. We expect two more House committees, the Ways & Means Committee and the Education & Labor Committee, to release proposals. We remain in close contact with all health committees to educate them on this issue. We also continue to engage with members of the New York Congressional delegation, especially Senate Minority Leader Chuck Schumer (D-NY) and those who serve on committees of jurisdiction.\nGNYHA continues to monitor Congressional efforts on drug pricing and we have met with the Senate Finance Committee to discuss our concerns with its proposal, the\nPrescription Drug Pricing Reduction Act. We also continue to educate lawmakers and staff on the need to pass legislation to address the nation’s deteriorating hospital infrastructure. GNYHA’s legislative proposal to address this vital issue can be found here.\nWe will keep our members apprised of any relevant developments on Capitol Hill.", "pred_label": "__label__POS", "pred_score_pos": 0.8871139883995056}
{"content": "What is Infertility Counseling?\nInfertility is a painful struggle. In the United States 10-15 % of couples have difficulty getting pregnant or sustaining a pregnancy. Even with the support of your partner, loved ones and medical team, you may feel isolated, confused, and beat down during your journey. Physically, countless tests, procedures, medications, and schedules can leave you feeling desensitized, disconnected, and robotic. Emotionally, stress, loss, fear, and failure can lead to feelings of anxiety, depression, and complicated grief.\nInfertility counseling can support you during this difficult time by providing a safe space for you to navigate the physical, emotional, and relational challenges of your journey in a healthy and productive way. Identifying and understanding emotions, working through trauma and loss, exploring options and goals, managing family dynamics and strengthening relationships are all important aspects of infertility counseling.\nWho is it for?\nHWP provides infertility counseling to individuals and couples.", "pred_label": "__label__POS", "pred_score_pos": 0.9273374676704407}
{"content": "Tipton County students will become critical readers, writers and thinkers who are self-directed in their learning.\nTipton County teachers will facilitate student-directed learning and develop strong readers by effectively implementing a high quality literacy curriculum that aligns to the science of reading:\n1. Explicit instruction of phonics and foundational\nskills in K-2 2. High quality texts that systematically build background knowledge 3. A deep focus on textual evidence and the comprehension of texts’ key ideas and details", "pred_label": "__label__POS", "pred_score_pos": 0.822787344455719}
{"content": "MIL-T-26025E (USAF)\n3.1.2.2 Dissimilar metals.\nUnless protected against electrolytic corrosion, dissimilar metals shall\nnot be used in intimate contact with each other. Dissimilar metals are defined in MIL-STD-889.\nThe vehicle shall be constructed so that parts shall not work loose\n3.1.3\nDesign and Construction\nin service, and shall withstand the loads, shocks, vibrations and other conditions incident to operation,\nshipping, and storage with minimum loss of time for maintenance, repair, and servicing. The design of\nthe vehicle shall ensure safe, efficient, and economical operation. All assemblies, controls, and installed\nequipment shall be located so there will be no adverse interference with each other or with operations and\nshall be readily accessible for maintenance, operation, removal, and replacement. The vehicle shall\ncomply with MIL-STD-1472, Federal Safety Regulations 49CFR571 and 49CFR393.\nThe vehicle, including all components, shall have a Mean-Time-Between-\n3.1.3.1 Reliability.\nFailures (MTBF) of not less than 250 hours demonstrated at an 0.9 confidence level. The vehicle shall be\ndesigned for a life expectancy of at least 14 years.\nThe vehicle shall be designed and constructed to provide the following:\n3.1.3.2 Maintainability.\nA minimum number of parts consistent with the performance required herein.\na.\nA minimum amount of time for assembling, disassembling, locating trouble sources and\nb.\nmaintaining the vehicle. Where practical, components shall be located for rapid\ninspection and recognition of potential failure.\nEase of adjusting, servicing and replacing parts and components.\nc.\nUse of readily available standard tools and equipment for maintenance.\nd.\nMaintenance with a minimum number of tools.\ne.\nf.\nMaximum repair time, excluding time to troubleshoot, of no greater than eight hours.\nMaximum total downtime to perform all daily scheduled maintenance and servicing\ng.\ntasks of no greater than 15 minutes.\nThe vehicle shall be designed so that one mechanic, using common hand tools, can perform the following\nmaintenance operations within the time specified:\nRemove, replace and adjust all engine driven belts - 3/4 hour.\n(1)\nRemove and replace alternator - 1/2 hour.\n(2)\nRemove and replace all filters, screens and strainers in all hydraulic systems -\n(3)\none hour.\nRemove and replace engine coolant system hoses - 1/2 hour.\n(4)\nDrain engine lubricating oil, remove and replace oil filter element (s) and refill\n(5)\ncrankcase - one hour.\nRemove and replace fuel filter element (s) - 1/2 hour.\n(6)\nDisconnect battery cables, remove and replace batteries and reconnect battery\n(7)\ncables - 1/2 hour,\nDrain torque converter oil and transmission oil, remove and replace all filter\n(8)\nelements and strainers and refill converter and transmission - one hour,\n5", "pred_label": "__label__POS", "pred_score_pos": 0.7566125988960266}
{"content": "Green coffee beans 100% Premium Quality\nGreen coffee beans are unroasted seeds of the plant Coffea Arabica. During roasting, the natural antioxidants present in the coffee beans are removed, which is not at all beneficial for our health. But as these green coffee beans do not go through the same procedure, they are considered as highly beneficial for our overall health.\nYou can enjoy green coffee without experiencing the high of caffeine intake Roasting the coffee beans removes most of the active ingredient in green coffee bean extract: a molecule known as chlorogenic acid. There are two active ingredients in green coffee bean extract: caffeine and chlorogenic acid. Its good for you. Theres more chlorogenic acid", "pred_label": "__label__POS", "pred_score_pos": 0.8212513327598572}
{"content": "-FWD.us Statement on Passage of the “Fairness for High Skilled Immigrants Act” WASHINGTON, DC. – FWD.us President Todd Schulte issued the following statement on July 10 th, after the U.S. House of Representatives passed H.R. 1044, or the“Fairness for High Skilled Immigrants Act,” by a vote of 365-65:\n“We congratulate Representatives Lofgren (D-CA) and Buck (R-CO), along with tens of thousands of directly-impacted advocates and organizers, on the passage of the ‘Fairness for High Skilled Immigrants Act’ by the House of Representatives today. With an overwhelming 365 votes in support, the bill’s passage represents a real example of bipartisan leadership in modernizing our legal immigration system.\n“This bill will help ensure those seeking permanent residency don’t face extraordinary wait times — projected at 50 years or more for people from countries like India and China — simply because of their country of origin. Eliminating ‘per-country’ caps for employment-based green cards and raising caps for family-based green cards will make the system fairer for immigrant families while also strengthening the United States’ ability to recruit and retain top global talent by establishing a fair and predictable path to permanent legal status.\n“Now that the House has acted, the Senate should immediately take up its bipartisan companion bill, S. 386, led by Senators Lee (R-UT) and Harris (D-CA).”\nBackground:\nThe bipartisan “Fairness for High Skilled Immigrants Act” aims to reduce and ultimately eliminate excessive backlogs for qualified immigrants seeking green cards by removing outdated limits and transitioning to a first-come, first-served system.\nUnder current law, only 7% of total green cards can go to individuals from any one country each year. This has led to extraordinary backlogs and wait times projected at 50 years or more for immigrants from populous countries like India and China. H.R. 1044 would eliminate the 7% cap for employment-based green cards and raise the cap for family-based green cards to 15%. Importantly, no one who is currently waiting to receive a green card will lose their spot in line.\nEliminating the “per-country” caps will strengthen the fairness and competitiveness of our immigration system. It will ensure individuals are not forced to wait decades for a green card simply because of their country of origin; it will also protect their children, who often face “aging out” of their dependent status during the years of waiting. And it will help the United States continue to recruit and retain top global talent by providing a clear and reliable path to permanent residency for those who wish to pursue it.\nWith over 300 bipartisan cosponsors, the “Fairness for High Skilled Immigrants Act” is one of the most popular bills in Congress and an opportunity for both parties to work across the aisle to strengthen our legal immigration system.", "pred_label": "__label__POS", "pred_score_pos": 0.6827255487442017}
{"content": "Enterococcus Clinical Veterinary MicrobiologyGenomic, Antimicrobial Resistance, and Public Health Insights into Enterococcusspp. from Australian Chickens\nDue to Australia’s management of antimicrobial use in poultry, particularly the discontinued use of avoparcin for nearly 20 years, it is hypothesized that vancomycin-resistant enterococci associated with human disease are not derived from poultry isolates.\nCommentaryThe New, New Daptomycin Breakpoint for Enterococcusspp.\nIn 2019, the Clinical and Laboratory Standards Institute revised the daptomycin breakpoints for\nEnterococcusspp. twice in rapid succession.", "pred_label": "__label__POS", "pred_score_pos": 0.9200688004493713}
{"content": "If you've been invited for a job interview, you've already impressed the prospective employer with the accomplishments and skills listed on your resume. But while the resume is important, the one-on-one meeting with the hiring manager can make or break your chances of receiving a job offer. You must now win him or her over with your professionalism and enthusiasm for the position.\nOne of the key factors for a successful interview is how well you prepare for the discussion. According to a Portuguese proverb, “He who is well prepared has half won the battle.”\nFollowing are some suggestions for tipping the scales in your favor:\n–", "pred_label": "__label__POS", "pred_score_pos": 0.9525591731071472}
{"content": "Reusable respirator cartridges and filters purify the air in workplace environments that contain heavy dust, fumes, gases and vapors. Cartridges and filters are available in different types. Some cartridges filter out gas and vapors, while others filter out only organic vapors. Filters typically protect against dust particulates and non-oily mists. However, some protect against both oily and non-oily mists. Cartridges and filters must be replaced on a regular schedule because they become clogged and less effective over time.", "pred_label": "__label__POS", "pred_score_pos": 0.9652510285377502}
{"content": "Why This Class\nAs a parent, you realize the only constant force in life is change. You also know accepting this reality is easier said than done—especially for your student as they grow towards adulthood. This course helps by exposing them to stories that display how human beings respond and adapt to change.\nMentors in this course guide students through some of the most striking works of modern world literature. In the process, students discuss and debate themes ranging from justice and mercy to cultural confrontation and personal redemption. Students also explore the emotional impact of large-scale changes in society—and learn how individuals can act as change agents to drive those shifts. To summarize their learning, students end the course by writing a personal essay called “This I Believe.”\nBy completing this course, students gain clarity on the core beliefs and values that will help them navigate the stormy seas of change. They can also relate more deeply to others who struggle to accept and embrace changes in their lives.", "pred_label": "__label__POS", "pred_score_pos": 0.858063817024231}
{"content": "An ambitious plan for poverty eradication is set to benefit thousands of below poverty line households in Bharatpur and make the district poverty-free by 2015. Through a well-planned strategy for self and wage employment generation, the plan would benefit 11,000 BPL families of the total of 49,394 such households in the district during the current financial year.\nAccording to the figures compiled by the Lupin Human Welfare and Research Foundation, which has formulated the poverty eradication plan, the total rural population in the nine blocks of Bharatpur district is 20.54 lakh, which includes the BPL population of 2.46 lakh.", "pred_label": "__label__POS", "pred_score_pos": 0.6136742830276489}
{"content": "Prochlorophytes, cyanobacteria and eukaryotic ultraplankton from coastal waters of the western Mediterranean Sea were analyzed by flow cytometry to obtain measurements of cell abundance, relative fluorescence per cell (related to cellular pigment content) and relative light scatter per cell (related to cellular size). Cyanobacteria were the dominant group followed by small eukaryotic cells and prochlorophytes. The depth distribution of these ultraplanktonic components in the euphotic layer showed a decrease in the cell abundance with depth in parallel to the decrease of irradiance. Relative cellular light scatter showed similar distributions at the different depths, indicating no variation in the cell size. However, relative cellular fluorescence showed a clear increase with depth, both in red (chlorophyll\na) and orange (phycoerythrin) fluorescence, suggesting photoacclimation. This was confirmed by the increase in cellular chlorophyll a concentration with depth, as derived from fractionated chlorophyll a analysis. The total fluorescence (F), calculated from the integration of the flow cytometric ineasurements of cellular fluorescence weighed by the cell abundance for each group, was significatively correlated with the fractionated chlorophyll a measurements, suggesting F as a useful means to characterize the group composition of bulk chlorophyll a, and therefore both as rough estimators of ultraphytoplankton biomass.", "pred_label": "__label__POS", "pred_score_pos": 0.7033959627151489}
{"content": "This type of dog training involves teaching your dog how to navigate an obstacle course as you run alongside him or her. While many people assume that only certain dog breeds, such as Border Collies, excel at Agility, the truth is that any type of dog can participate in this fun activity. Here, how Agility training can benefit both you and your dog will be discussed.\nBonding\nSpending quality time with your dog is the best way to develop a deep and lasting relationship. Teaching your dog new tricks in a fun and enthusiastic way will strengthen your connection while improving your ability to communicate with your pet.\nExercise\nDuring an Agility session, dog and owner must run through an obstacle course as quickly as possible without making any mistakes. The dog must run, jump, and turn, which provides a great workout for an active pup. Similarly, the owner runs alongside the dog to direct him or her where to go throughout the course. This high-paced activity is a definite calorie burner!\nMental Stimulation\nMany dogs (and humans!) require a mental challenge in addition to physical exercise. The constant learning, thinking, and navigating involved in Agility training makes this activity the perfect way to exercise your dog’s brain. Additionally, humans must continually learn how to communicate in new ways with their dogs to achieve the most success!\nSocialization\nThe main component of maintaining a healthy and balanced dog is socialization. Agility, as a part of dog training, is a great socialization activity because it requires dogs to try new and potentially scary things as they grow more advanced. For instance, running through a tunnel or over an A-frame can be frightening to dogs, but they are taught how to confront these fears safely. Dogs are also given an opportunity to socialize with new animals and humans during Agility classes and competitions.\nSimilarly, humans can socialize with like-minded individuals. Whether searching online forums for Agility advice or attending classes or competitions, Agility training is a great way to meet new people.\nUltimately, Agility training is beneficial for both dogs and humans because it provides exercise, mental stimulation, socialization, and a chance for bonding. Regardless of your dog’s age, size, or breed, Agility can be great for you both!\nDon’t forget to adjust your dog’s food accordingly the activity.\nDog tracking system comes in handy as it allows you to track both more closely. You can already pre-order Actijoy system on our website to keep track of your dog’s activity, nutrition and changes in behavior in one step.\nall dogs should be treated as individuals. The Actijoy blog is for educational and entertainment purposes only. In the case of emergency, always seek qualified health care from a local veterinarian or emergency facility. Actijoy™ blogs are not designed to treat, diagnose, or prescribe medication for your pet. Please note:", "pred_label": "__label__POS", "pred_score_pos": 0.5151830911636353}
{"content": "Minister of State, Federal Capital Territory (FCT), Ramatu Aliyu, has charged the youth to leverage the N75 billion Nigerian Youth Investment Fund ( NYIF) the Federal Government has introduced to empower them economically.\nAliyu made the call at the maiden edition of NYIF celebration in Abuja. She identified poverty and unemployment as factors that drive youth to violent extremism and crime.\nThe minister noted that the NYIF was a demonstration of President Muhammadu Buhari’s sensitivity to the affairs of youth. He explained that it was in a bid to give the youths a lift that the government created a new N75 billion youth fund.\nShe, therefore, called on Nigerian youth to leverage the government’s social investment scheme and several other soft loan schemes available to youth entrepreneurs to enhance job creation.\nAliyu stated that as part of measures to mitigate this ugly trend, the Federal Government since 2015 had initiated programmes to reach out in other to ameliorate the vulnerabilities of youths in the country.\nThe minister revealed that the FCT administration had been contributing its best to support the federal government initiatives, adding that the administration had been generating a couple of peculiar intervention programmes to assist young people, their families and communities on a sustainable routine basis.\nShe hinted that the FCTA, through the Youth Development Department of the Social Development Secretariat, had trained youths in various viable economic skills at the FCT Youth Support Centre, Nyanya.\nThe acting secretary of Social Development Secretariat, Kelvin Ike, stressed that no nation could witness any meaningful progress and development in an atmosphere of persistent restiveness due to neglect of the youths.\nHe stated that everything must be done to ensure a meaningful life for young people, stressing that it was in this light that the administration had put measures in place to support the youths despite the unfriendly economic challenges.", "pred_label": "__label__POS", "pred_score_pos": 0.9768933057785034}
{"content": "Estimated Total Annual Driving Costs for:\nTotal Cost per Kilometre $0.40 Average Fuel Economy (L/100km) 7.65 Fuel Cost per Year (Gas) $1,539.58 *Cost is representative of owning or leasing a vehicle for 5 years.\nOver 5 years the 2019 Toyota Rav4 XLE 4D Utility FWD\nemits 17 582 kg of greenhouse gas\nOver 5 years the 2019 Honda CR-V LX 4D Utility 2WD\nemits 17 548 kg of greenhouse gas\nThese prices are provided by gasprices.caa.ca\nThe reduction in value of a vehicle incurred during a given period of time.\nThe cost of keeping your vehicle in running order, including the OEM recommended maintenance schedules and unscheduled maintenance costs (ex. tires and battery).\nThe cost for maintaining a driver’s license and registering the vehicle in your province.\nThe cost to insure a vehicle, which depends on a variety of factors. Assumptions are based on a driver under the age of 65, six years of driving experience with no accidents, living in a suburban/ urban location, personal use, with a $500 deductible. We also include personal liability, medical, property, and insurance for an uninsured driver.\nThe monthly payment is an estimate that assumes a 15% down payment using current finance rates in your area, and includes the principal amount of the loan and interest payments.", "pred_label": "__label__POS", "pred_score_pos": 0.5241096019744873}
{"content": "Published on August 21st, 2020 | by Sumit Bhowal Tips For Developing Effective Healthcare Teams\nAnyone whose had a loved one in the hospital knows the importance of healthcare heroes. Not only do they save lives, but they teach others how to take better care of themselves and provide emotional support during difficult times. It is no wonder that healthcare workers have high turnover and burnout rates. Therefore, as you prepare your healthcare workforce management strategies, consider implementing some added teamwork and support policies for these employees.\nConsistent Communication\nIn healthcare settings, preventing miscommunications is vital because misunderstandings lead to errors that may be detrimental to patients’ health. Therefore, healthcare leaders must implement strategies that ensure clear, effective communication. For example, leaders should establish formal communication guidelines for different situations, such as sharing patient information among medical team members.\nLeaders may also consider providing or promoting communication education that teaches the medical team members how to communicate clearly and ask open-ended questions. Training may also include learning skills and developing effective follow-up questions.\nHealthcare managers should also clearly communicate the organization’s goals and objectives. Management’s expectations should be clearly communicated to each employee. In addition, your employees should understand all the support services you offer.\nCultivate Compassion\nEvery employee in a healthcare facility should show compassion toward the patients and their loved ones. Although each practitioner has a specific job, they should consistently reassure their visitors and ensure they have what they need.\nHowever, compassion starts with leadership. Not only should healthcare leaders offer compassion to their patients, but they should also offer compassion to their employees. Therefore, management should ask the patients if they need anything and give them assurance that they will be supported throughout their time in the facility. In addition, leaders should actively observe their employees to ensure they have everything they need.\nPromote Teamwork\nMedicine requires collaboration among many specialized team members, as well as patients and their loved ones. Therefore, team goals should be clearly outlined and reviewed frequently. Teams should have consistent documentation and communication guidelines. They should adopt the same approach and language with their patients. They should foster the same environment and service delivery strategies.\nEffective teamwork also requires complete teams. Therefore, healthcare managers should ensure their teams are fully staffed. Staffed teams allow the employees to focus on their part of the team’s goals. This allows leadership to maximize human capital while preventing overworked employees.\nTeam-specific goals may include efficiently using resources, education requirements and productivity. Focusing on growth encourages the employees to remain focused and committed to the organization. It also encourages them to review and stretch their career goals. When the employees are focused on their team and personal growth goals, they provide more efficient and effective serviced to the patients, which improves their satisfaction.\nHealthcare personnel are valuable. They not only treat patients, but they also provide comfort to patients and their loved ones. Despite the steady increase in medical service demands, these employees must still deliver exceptional patient care, reduce waste and maintain patient records. Therefore, healthcare leaders should seek out ways to ease the burden on their workers.", "pred_label": "__label__POS", "pred_score_pos": 0.9047254323959351}
{"content": "A sound leadership training strategy can be the difference between lackluster courses with disappointing results and improved job performance that drives organizational success.\nDeveloping relevant, engaging training programs that align closely with business goals is crucial for lasting performance sustainment.\nUse this infographic from The Center for Leadership Studies to breathe new life into your leadership training strategy and watch business results soar.\nTrouble viewing this PDF? You can download here.", "pred_label": "__label__POS", "pred_score_pos": 0.5617753267288208}
{"content": "In\nRhinoceros, the gradual takeover of society by the beasts is made to seem natural and, therefore, inevitable. Eugene Ionesco presents the protagonist, Bérenger, as a conventional person with normal goals and aspirations. Initially, as he does not question his society’s values, he is not motivated to challenge them. Everyone is equally confused by the animals running loose. As a few individuals realize that the animals are transformed humans, they wonder what is happening but do not try to stop it. As more people change, Bérenger continues to observe but remains unaffected; he regards their behavior, like their new appearance, as aberrant. A few exceptions do not affect society overall.\nBetween acts 2 and 3, after his friend Jean becomes a rhinoceros and attacks him, Bérenger starts to understand that he is now in the minority, which everyone else identifies as abnormal. When his girlfriend, Daisy, leaves him to join the herd, he is left solitary and alienated. Because he clings to his humanity, now fiercely resisting the universal transformation, the human condition as Ionesco presents it is precisely that combination of isolation and resistance to mob rule.", "pred_label": "__label__POS", "pred_score_pos": 0.9074034094810486}
{"content": "Ever more efficient renewables, digitalization, decentralization, a smarter grid and innovative market instruments are expected to radically transform the future energy system, calling for strategic and forward-looking decisions by energy policy makers. IRENA highlights how best practices – namely inclusive and participatory processes coupled with a proper accounting for innovation – can lead to a better development and use of long-term energy scenarios (LTES), shedding also new light on the vast potential for jobs creation along the renewable energy transition.", "pred_label": "__label__POS", "pred_score_pos": 0.5905187129974365}
{"content": "The Quality Infrastructure Investment Database is an initiative of the G20 under the 2019 Japanese Presidency, in collaboration with the Global Infrastructure Hub, the OECD and the World Bank.\nThe database includes resources and facilities relevant to Quality Infrastructure Investment under the principles of Sustainable Growth & Development, Economic Efficiency, Environmental Considerations, Building Resilience, Social Considerations, and Infrastructure Governance.\nThe Guidance Note’s overall aim is to help accelerate the flow of quality infrastructure projects, including through mobilising private capital and supporting project preparation. The analysis has sought to identify some of the unique niches and roles that such institutions can occupy and play in support of government objectives and policies in these areas.", "pred_label": "__label__POS", "pred_score_pos": 0.7818727493286133}
{"content": "This chapter will primarily focus on obtaining permanent residency via Program Electronic Review Management [hereinafter PERM] certification process for skilled workers, professionals, and advance degree holders. Currently, (other than National Interest Waiver Cases) any such PERM case must be first certified by the Department of Labor. This process can take several months and often costs thousands of dollars in advertising and other fees.\nWe would have the Department of Labor to issue an annual list of occupations that have been clearly recognized as in “short demand” for each state. The list would also include the Department of Labor’s findings on what the minimum requirement for the position should be as well as the minimum wage. As these occupations would be recognized by the Department of Labor as in demand, the standard labor certification process of pre-advertising and wage requirement would be omitted.", "pred_label": "__label__POS", "pred_score_pos": 0.8595167994499207}
{"content": "I should have known that my sister would be the one to usher me through this moment of danger, possibility, and divine intervention. After all, at the beginning of my life, it was Miriam who watched over me as I floated down the Nile and then courageously suggested to Batyah, Pharaoh's daughter, that she could find a nursemaid for the baby (me) that had been drawn from the water. And now, as I once again found myself floating in uncertain waters, it was Miriam who kept me from sinking beneath the eddies and waves of God’s power.\nI was struggling. Something within me had felt different from the moment I began my descent from God’s mountain. I was overwhelmed by the power of the experience and I couldn’t find the time or space to process this intense journey of mine.\nI thought I had already acclimated myself to the constant transformations and upheavals that had made me both a divinely-appointed guide for my people and a man lonely in the middle of thousands. At the burning bush,\nmy life’s purpose was refocused, and when Aaron arrived to partner with me, I realized that every aspect of my life would be remade to fulfill God’s needs. My heart hurt when something shifted in my relationship with my beloved, Zipporah, the changes so subtle that I wondered if she even noticed them. After I had spoken to God, Zipporah began to treat me differently, giving me more space than I would have liked. At times, it felt like she had begun to see me as a prophet even though I was desperate to just be her husband and fall into her arms.\nWhen I returned to Egypt, the Israelites treated me as if I was entirely foreign to them. After I successfully followed God’s instructions and brought forth those ten plagues, the people - mine and the Egyptians - gave me a wide berth. Did they fear me? Were they in awe of me? It was as if the closer I became to God, the greater the distance grew between me and my people.\nEven my mothers seemed to hold back. At the Red Sea,\nGod’s power coursed through my veins, almost taking me out, and in that moment, I knew that two mothers - Batyah and Yocheved - were aware of my increasing weakness. But they didn’t come to me as they so often had when I was a child. When they looked at me, did they recognize their son? Or was I someone completely transformed? Perhaps into someone who was no longer theirs?\nRemaining on top of God’s mountain for forty days and nights was incredible- overwhelming, disorienting, transcendent, and more. I knew even as I experienced God’s presence that I would never be able to adequately explain what had happened.\nAs I descended from the mountain, I felt… different.\nAll the moments that had come before, when I thought I had been utterly transformed, paled in comparison. Now that I had experienced Sinai, it was as if a world of meaning- once opaque and hiddened- was now brightly illuminated. I could now see through the surface of things and could perceive clearly- what was and what is- in both the wilderness and in people’s souls. It felt like my mind was on fire. Everywhere I looked, it was as if everything was being illuminated by the light of a thousand candles.\nAnd yet, even as I probed my newfound abilities, I saw how they again separated me from my people. Now even my kinsmen refused to meet my gaze. I perceived an intermix of wonder and fear on my people’s faces. I was standing among multitudes and yet I felt shunned and alone.\nSuddenly, I felt the tides of divine and human power rising up to my throat, threatening to pull me under. But then, out of the sea of strangers who wore the faces of friends, my sister swam into view. Miriam hurried to me, pushing people out of her way and calling my name. She grabbed hold of my hands and guided me gently into my tent.\nShe helped me settle onto the floor, and then, looking so deeply into my eyes that she seemed to speak directly into my soul, she told me what everyone was seeing: I was aglow.\nShe told me I was radiating a bright light from my eyes, my face, my whole being. I was startled by her explanation, worried that I had transformed from a man into something else entirely. How could I be a father, a husband, a brother, a son, if I was not a man? Had I become something foreign?\nWe sat together for some time. Miriam did not try to comfort me with hollow words. Instead, she used her presence to remind me of the human connections that bound me to this earth. Eventually, I began to understand. I was still Moses, but I was no longer only the man I had been. I had been transformed: by the encounter with God and by the process of inscribing the holy utterances of the Torah itself.(1)\nI covered my face with my hands trying to blot out this strange, new knowledge, as God had blotted out the sun back in Egypt. I turned to my sister and unburdened my soul. I confessed to her that I was exhausted from facing the stares and the fears of our people. I wept as I explained how I felt that I must always be strong and resolute- the kind of leader that people prefer to remember. She let me cry and share without comment, without judgement.\nThe tent fell into silence, and for a long time, we simply sat together, drawing strength from one another and our connection. Then Miriam slowly removed my hands from my face, and looked deeply into my eyes. She offered me a lesson that had been hard won from her own experiences with the yolk of prophecy. She explained that the connection that we have with God is both a burden and a blessing. She reassured me that over time, I would learn to balance both elements just as she had done. She told me that eventually I would understand that the light of God’s love, of God’s trust, was a precious gift, offering great insight. My connection to our God would help me clarify my confusion about people’s intentions and differentiate between friends and foes.\nShe counseled me to embrace God’s light and to find ways to preserve my own identity lest it be burned away by the power of divine illumination.\nSuddenly her eyes lit up, and, after telling me to wait, she ran out of the tent. Moments later, she returned with a large piece of cloth. She explained, “We hang curtains between the Holy of Holies and the Israelites, cloth that protects our people when the power of God is too much. With a veil you would be able to do the same. You could cover your eyes when the the light is too much for you or for the people. It could give you the space to just be Moses the man.\nHer solution was simple and reflected both the wisdom of a prophet who understood the burdens of another, and the love of a sister who knew the heart of her brother.\nWe hugged. I thanked her, telling her how much I valued her strength, advice, and partnership. And, then we left the tent where we had stolen time as brother and sister and went out to handle our responsibilities to our people. She offered me a confident nod, and I walked on, clasping my veil in a tight grip.\nI went to speak to Aaron and the elders. And then to the people. As the day ended and my feet dragged with exhaustion. I felt exhausted and fragile. But rather than become overwhelmed by the toll that prophecy had taken on me, I followed my sister’s advice. I put a veil upon my face (Exodus 34:33) and wrapped myself in privacy and peace.\n1-Midrash Tanchuma and Prof. Aviva Gottleib Zornberg", "pred_label": "__label__POS", "pred_score_pos": 0.8023984432220459}
{"content": "If you have one or more missing teeth, then you may feel self-conscious when you are speaking with friends or out on a date. If you have missing front teeth, then you may think that people are staring at you and refrain from speaking. If you have missing back teeth, then it can be difficult to eat many foods, such as meat and vegetables. This difficulty engaging in common social activities can put a damper on your self-esteem and ability to interact with people. However, your cosmetic dentist can address your dental issue and boost your self-esteem with dental implants in San Jose. Read on to see how one or more dental implants can turn your social life around.\nDental implants are placed directly into your jawbone, and they connect with a dental crown to create a suitable tooth replacement. If you need more than one tooth replacement, then one or more implants can be used in conjunction with implant-supported dentures or bridges. These tooth replacements will look and feel like your natural teeth, and you can smile, speak, and eat without difficulty. Speak with your dentist about boosting your self-esteem with dental implants.", "pred_label": "__label__POS", "pred_score_pos": 0.5941590070724487}
{"content": "Claim\nA photograph shows red-tinted clouds over a large wildfire in California.\nOrigin\nA photograph purportedly showing eerily beautiful, red-tinted clouds over a large wildfire in California began making its way online in early August 2018:\nThe wildfire in California burned through more than 270,000 acres in California in August 2018, making it the state’s second largest fire in history. This photograph, however, didn’t have anything to do with that enormous conflagration.\nThis image images to show Altocumulus clouds taken from an airplane at sunset. Before this image was attached to the wildfire claim, it was shared with the following caption on Reddit: “Altocumulus clouds & a sunset at 30,000ft.”\nInterestingly, one of the comments on that 31 July 2018 post joked that it would be an interesting “plot twist” if this image were actually taken over California. A few days later, this photograph was in fact being shared with the claim that it showed “Clouds over the California fires, 30,000 feet up.”\nSome commenters asserted that this image was originally shared by meteorologist Owen Shieh and posted a screenshot purportedly showing Shieh’s original Facebook message:\nHoaxEye, a Twitter account dedicated to debunking viral images, managed to contact both Shieh and Province and posted a screenshot of their correspondence. Province confirmed that he was the one who took the photograph and stated that the image actually shows a sunset somewhere over Hawaiian waters:\n— HoaxEye (@hoaxeye) August 8, 2018\nShieh also confirmed to us that this photograph was originally posted to his Facebook page (where it is only visible privately to friends) and stated that the viral claims attached to this image are incorrect.\nMichael Lowry, an atmospheric scientist, explained why these clouds appeared to “glow” red in the photograph (which he tweeted was taken near Hawaii, not California, and was unrelated to fires or volcanoes):\nThis is woefully dishonest. This was taken from a C-17 ~40 min from Oahu, not CA (and not by Peter Singer). The glow is from a sun angle below the horizontal plane illuminating shallow altocumulus clouds. Not fires. Not lava. Thankfully I don’t believe everything on the twitters. https://t.co/OLFKFrzioI\n— Michael Lowry (@MichaelRLowry) August 6, 2018\nThis photograph also resembles other media capturing sunset views taken from altitudes just above a cloud layer:\nWildfires do create unique-looking clouds, but they wouldn’t resemble the ones shown in the viral photograph. CNN meteorologist Brandon Miller explained that pyrocumulus clouds often form over wildfires, as the extreme heat of those blazes forces air to rise rapidly:\nNormal cumulus clouds form because the sun’s rays heat the ground, forming warm air that rises because it is less dense than the cooler air above. As it rises, the air cools and condenses to form the cloud.\nDuring a wildfire, however, the extreme heat from the flames forces air to rapidly rise. As the fire burns trees and other plant life it causes the water inside them to evaporate into the rising air. This additional moisture in the atmosphere condenses in the cooler air above, on smoke particles also produced by the fire.\nHere’s a video from Accuweather about these pyrocumulus “fire clouds”:", "pred_label": "__label__POS", "pred_score_pos": 0.5445836782455444}
{"content": "Hy-Vee has teamed up with fellow food and drug retailers to help reduce plastic waste by joining the Consortium to Reinvent the Retail Bag as a supporting partner.\nThe coalition, launched over the summer, was founded to test options to the single-use plastic shopping bag now used by mass retailers nationwide. CVS Health, Target and Walmart are the consortium’s founding partners, while The Kroger Co. serves as the group’s grocery sector lead partner. Walgreens participates as a supporting partner, and investment firm Closed Loop Partners serves as managing partner. Dick’s Sporting Goods takes part as sports and outdoor retailer sector lead partner.\nWhen the consortium was announced, the participating retailers pledged more than $15 million toward the Beyond the Bag Initiative, a three-year effort that calls on retailers to “think outside the box” to address the global waste issue of plastic shopping bags.\n“The opportunity to join the Beyond the Bag Initiative and address the shared challenges presented by single-use plastics with some of the largest and most influential retailers in our country is crucial as we remain committed to reducing our environmental impact,” Jay Marshall, vice chairman and president of Hy-Vee’s supply chain and subsidiaries, said in a statement. “Through this collaboration, we can truly move the needle on a global waste issue and bring to life some much-needed solutions. We look forward to contributing our knowledge and insights and collectively collaborating with other consortium partners to pave the way for a more sustainable future.”\nMore than 100 billion single-use plastic retail bags are used annually in the United States, and less than 10% are recycled, according to the consortium, which also noted that a plastic bag’s lifespan far outlasts it usage. The average time of use for a single-use plastic bag is 12 minutes, versus an average of 1,000 years for it to break down. That exacts a heavy toll on the environment, as plastic retail bags are among the top 10 items found on beaches and waterways worldwide each year.\nWest Des Moines, Iowa-based Hy-Vee operates more than 275 supermarkets and drugstores in Iowa, Illinois, Kansas, Minnesota, Missouri, Nebraska, South Dakota and Wisconsin.\n“We are thrilled to welcome Hy-Vee to the Consortium to Reinvent the Retail Bag. The collaborative power of our consortium enables us to have impact at scale and accelerate the pace of innovation to find alternatives to the current retail bag,” commented Kate Daly, managing director of the Center for the Circular Economy at Closed Loop Partners. “We continue to invite other retailers to join us and send a unified signal for transformational change to address this long-standing environmental challenge.”\nIn August, the Consortium to Reinvent the Retail Bag launched a global innovation challenge to source solutions — including technology-enabled reuse models, new materials, and software and hardware innovations — to replace the today’s plastic bag. The challenge, which closed last week, drew more than 450 submissions.\nConsortium partners, including retailers and environmental advisory partners, and third-party experts will review and select the shortlist and winners. All submissions are judged according to sustainability, accessibility, customer behavior and alignment with reuse and recovery infrastructure. Winning concepts are eligible to receive a portion of $1 million in funding, participate in a circular accelerator to receive further assistance in scaling, and access testing and potential pilot opportunities.\nOther consortium participants include stakeholders across the plastic bag value chain, such as suppliers, materials recovery facilities, municipalities and advocacy groups.\n“Our commitment to phase out single-use plastic bags across our enterprise is a critical part of our Zero Hunger | Zero Waste social impact plan,” stated Lisa Zwack, head of sustainability at Kroger. “We’re thrilled to welcome Hy-Vee to the consortium, and we encourage other retailers to join our search for innovative, sustainable solutions to the traditional single-use plastic bag.”", "pred_label": "__label__POS", "pred_score_pos": 0.6630141735076904}
{"content": "Anjeneya Dubey is the director of performance engineering for McGraw-Hill Education, a learning science company that delivers personalized learning experiences. His responsibilities include ensuring that every product built is high performing, highly scalable, highly available, highly reliable, and fault tolerant. In his past five years with McGraw-Hill, Anjeneya has built automated performance engineering frameworks that detect performance and scalability issues early on in a fast-paced agile environment. Previously he was a technology consultant, with experience across the spectrum of the product delivery life cycle from development to testing to site reliability engineering activities in complex high-visibilty enterprise environments.\nIn the world of continuous integration and continuous delivery, the importance of ensuring good performance has increased immensely. While functional and unit testing are relatively easier to integrate into these processes, performance engineering has typically raised more challenges. Here's how you can mitigate them.", "pred_label": "__label__POS", "pred_score_pos": 0.9041294455528259}
{"content": "By Zach Cavanagh\nThe California Department of Public Health will now allow for the resumption of youth sports workouts, conditioning and physical education with proper physical distancing, according to another round of new guidance released on Monday, Aug. 3.\nThe guidance applies to all youth sports, including school sports. However, school sports may remain unaffected by the latest guidelines, as campuses may not physically reopen until their county has been off the state monitoring list for 14 consecutive days, per the state guidelines. Orange County currently remains on the state monitoring list.\nThe Capistrano Unified School District informed district athletic teams that a plan to return to the Phase 1 Conditioning Camps will be announced on Tuesday, Aug. 11. Those camps were originally scheduled to begin on July 6 before they were canceled.\nYouth sports games, tournaments and any events that would require close contact or would “promote congregating” are still not allowed. Youth sports practices and conditioning will be allowed only when physical distancing of six feet and a stable, preferably smaller, group of athletes can be maintained.\nYouth sports are encouraged to work out outdoors, but if activities take place indoors, a cloth face covering is required. The guidance states that all activities that require heavy exertion should then take place outside without a face covering and with physical distancing.\nThis is the latest upswing on the rollercoaster of youth sports guidelines in California.\nSchool sports and many youth leagues closed down in mid-March as the state rolled out its first shutdown guidance. Some youth leagues began to resume small operations over the next two months before Orange County released guidance on June 15 that said youth sports practices were allowed to resume via the state’s day camp guidance.\nYouth leagues sprung back into action, and local high schools were set to open conditioning camps on July 6. However, those school camps were mostly shut down before they started following a letter from the Orange County Department of Education and further state guidance on July 8 that shut down all youth sports activities until Monday’s latest guidance.\nOn July 20, the CIF State and CIF-SS offices shifted the start of high school sports seasons into December and January. However, until schools can physically reopen, those dates remain tentative.\nZach Cavanagh Zach Cavanagh is the sports editor for Picket Fence Media. Zach is a multiple California Journalism Award winner and has covered sports in Orange County since 2013. Follow him on Twitter and Instagram @ZachCav and follow our sports coverage on Twitter @SouthOCSports. Email at zcavanagh@picketfencemedia.com.", "pred_label": "__label__POS", "pred_score_pos": 0.6080637574195862}
{"content": "Through participation in an Enneagram Staff Training, staff members will learn the nine diverse perspectives of the Enneagram types the unconscious placement of attention that drives energy particular blind spots that limit growth and maintain unhealthy patterns the unconscious driver of reactivity each type’s verbal and nonverbal communication style strategies for more effective communication inherent strengths of each type Outcomes broader perspective that honors diverse opinions becoming more curious and less judgemental strategies for moving beyond limiting patterns, creating more effectiveness in work as strengths expand more neutrality and presence in difficult time engaging conflict creatively, allowing more possibilities to emerge increased clarity in communications creating efficiency and smooth flow of information balanced use of strengths with clear boundaries making space for other’s strengths\nWhile working with staff, Sandra underscores the perspectives represented on the staff and their strengths as well as those perspectives that are missing. Identifying team blind spots and naming the missing perspectives leads to ensuring those perspectives are included in discussions and decision-making. Asking a staff member to bring the missing perspective into the meeting offers an effective way of increasing cognitive diversity on the team.", "pred_label": "__label__POS", "pred_score_pos": 0.731374979019165}
{"content": "When working with families and children I take a team approach, where all members of the family are considered a part of the treatment plan and solution. I use age-appropriate, play-based, creative interventions to help children and parents find calm physical and emotional states. Combinations of these therapies assist parents in better understanding their child’s behaviours, and improve connections and overall harmony within the home.\nFamilies come to me when their children have challenges with:\n– tantrums\n– emotional expression – mood swings – ADHD/hyperactivity – school/social challenges – defiance – ASD Parents are empowered through:\n– parent skill-building\n– gaining insight into reasons for their children’s behaviours – learning de-escalation strategies – learning to assist their children in emotional regulation – improve connection between family members Sessions can include:\n– child-centre, age-appropriate interventions\n– play-based, creative interventions – emotional regulation and coping strategies\nIf you think I can help your child and family, click the button below to set up a call.", "pred_label": "__label__POS", "pred_score_pos": 0.5738046169281006}
{"content": "Abstract\nAntiangiogenic therapy improves survival in patients with advanced stage cancers. Currently, there are no reliable predictors or markers for tumor vessel response to antiangiogenic therapy. To model effective antiangiogenic therapy, we disrupted the VEGF gene in three representative cancer cell lines. HCT116 xenografts had low proportions of endothelial tubes covered by pericytes that stained with α-smooth muscle actin (SMA) antibody. Upon disruption of VEGF, HCT116\nVEGF-/- xenografts had significantly decreased tumor microvessel perfusion compared with their parental counter-parts. Furthermore, HCT116 VEGF-/- xenografts mounted a tumor-reactive response to hypoxia, characterized by the induction of hypoxia-inducible factor-1 (HIF-1) target genes. One highly induced protein was DPP4, a measurable serum protein that has well-described roles in cancer progression. In contrast, LS174T and MKN45 tumor xenografts had high proportion of endothelial tubes that were covered by SMA+ pericytes. Upon disruption of VEGF, LS174T VEGF-/- and MKN45 VEGF-/- xenografts maintained tumor microvessel perfusion. As such, there were no changes in intratumoral hypoxia or HIF-1α induction. Together, these data show that the extent of tumor vessel response to angiogenic inhibition could be correlated with (a) the preexisting coverage of tumor endothelial tubes with SMA+ pericytes and (b) differential tumor induction of HIF-1 target genes. The data further show that DPP4 is a novel marker of HIF-1 induction. Altogether, these preclinical findings suggest novel clinical trials for predicting and monitoring tumor vessel responses to antiangiogenic therapy. ASJC Scopus subject areas Cancer Research Oncology", "pred_label": "__label__POS", "pred_score_pos": 0.8913978934288025}
{"content": "In a recently published article for Newsline, a publication of the Federation for Children with Special Needs, Bob Crabtree reflects on the slow process between the time that a substance is recognized as toxic to children and the time that legislatures act (if they act at all) to regulate its use, and the resulting harm to children.\nIn the article,\nPublic Toxins and the IDEA: In Quest of an Accountable Economy and a Fully Funded IDEA, Mr. Crabtree discusses the implications of this regulatory failure for disability advocacy, with emphasis on the need for a robust independent regulatory system to determine the possible neurodevelopmental effect of materials before those materials are allowed in the marketplace. In addition, Mr. Crabtree argues that Congress must fully fund IDEA to provide adequate support to all children with disabilities, including those children whose disabilities are caused or amplified by harmful products in the marketplace.\n(Readers are encouraged to return to this site with comments if they are so moved, as the Federation’s site does not include that option.)", "pred_label": "__label__POS", "pred_score_pos": 0.5863787531852722}
{"content": "Title\nTempered radicalism in the academy: Scholar-activism in the neoliberal university\nDocument Type\nArticle\nPublication Date\n11-2020\nPublication Title\nJournal of Social Issues\nAbstract\nUsing a collaborative critical personal narrative methodology grounded in intersectionality, we interrogated tensions in identifying ourselves as tempered radicals and scholar‐activists who were involved in a local university‐community activist organization. We assert the value of informal activist spaces within the university and identify issues related to the lack of recognition of scholar‐activism as legitimate scholarship, including the paradox of universities as colonizing and liberatory spaces for community engagement and activism. Our themes highlight how mentorship affects scholar‐activism and how activism transforms and disrupts the neoliberal university. Yet, activism is rendered invisible, making homeplaces for scholar‐activism critical for students, faculty, staff, and the community to address structural inequalities within and outside of the university. We conclude with recommendations to improve mentorship for scholar‐activists, to revise tenure and promotion policies to include scholar‐activism, and to recognize spaces within the academy that honor scholar‐activism as a critical form of praxis informed by intersectionality.\nFirst Page\n1\nLast Page\n22\nDOI\nhttps://doi.org/10.1111/josi.12401\nISSN\n1540-4560\nRepository Citation\nRichter, Jennifer; Farago, Flora; Swadener, Beth Blue; Roca-Servat, Denisse; and Eversman, Kimberley A., \"Tempered radicalism in the academy: Scholar-activism in the neoliberal university\" (2020).\nFaculty Publications. 29. https://scholarworks.sfasu.edu/humansci_facultypubs/29\nTell us how this article helped you.", "pred_label": "__label__POS", "pred_score_pos": 0.6556268334388733}
{"content": "Fish oil is a rich source of omega 3 fatty acids, EPA and DHA and turmeric is a source of curcuminoids.\nThe quality recipe and exacting nutritional specifications of Dib’s ensures your dog receives essential nutrients that are required to maintain health and vitality.\nThe dense nature of Dib’s Premium Dog Bits aids in oral hygiene, as the gentle, abrasive texture of Dib’s massages and cleans teeth and gums.\nThis assists in the removal of plaque, which is a precursor to gingivitis and periodontal disease.\nIngredients\nDib’s is formulated from a selection of the following ingredients: Cooked meat or meat by-products derived from beef, lamb, poultry or pork, cooked fish or fish by-products, fish oil, animal fat, vegetable oil. Cooked cereals and products derived from wheat, canola and soybeans. Lysine, methionine, threonine, tryptophan, natural flavours, bentonite, salt, turmeric, enzymes and antioxidants.\nVitamins: A, D3, E, K, B1 (thiamine), B2 (riboflavin), B3 (niacin), B5 (pantothenate), B6 (pyridoxine), B7 (biotin), B9 (folic acid), B12 (cobalamin) and choline chloride.\nMinerals: Calcium, phosphorus, sodium, chloride, cobalt, copper, iodine, iron, manganese, organic selenium and zinc.", "pred_label": "__label__POS", "pred_score_pos": 0.9609721302986145}
{"content": "The widespread loss and damage consequent on the COVID-19 pandemic will inevitably cause a large number of businesses and individuals to consider the means by which they may recover their loss, either by suing potential wrongdoers (e.g. employers who insist on employees coming to work, resulting in contraction of the virus) or by making claims under insurance policies.", "pred_label": "__label__POS", "pred_score_pos": 0.6127392649650574}
{"content": "Those who diligently seek me shall find me.\nBuilding a relationship with Jesus requires daily communication with Him.\n“Trust in the Lord with all thine heart; and lean not unto thine own understanding. “In all thy ways acknowledge Him, and He shall direct thy paths.” “Be not wise in thine own eyes; fear the Lord and depart from evil.” Prov 3\nWe may lose sight of the importance of daily prayer due to a busy schedule, but we must put God first in all our endeavors for His protection, grace, mercy and provision.\nHis grace is sufficient. He provides blessings to the just and the unjust, but when you are in a relationship with Him you are open to receive the many benefits and promises that He gives freely to His children.\nPrayer is more than asking God to do or give you something. It’s an act of worship and praise.\nIt’s in the quiet moments when we acknowledge who He is that provides us peace, inner joy and strength to go through our day with high expectations. When we pray over our lives and others, we will gain a sense of inner harmony and peace despite what we may encounter through the day.\nSometimes we may feel our prayers go unanswered, but God has our best interest at heart. It must be His will not our own. Everything happens for a higher and greater purpose that we may not understand at the time, but through faith, obedience and patience, we will inherit the promises of God.\nGod works in seasons. Abraham and Sarah, The Apostle Paul, Daniel, Joseph, Job and Moses are examples of people who had to endure and wait for the promises of God.\nI write this piece to encourage you to endure any situation, circumstance or obstacle. I am a living example of the realities of deterred dreams, dealing with extreme difficulties and disappointments, but God never fails and His word does not return void. (Isaiah 55:11)", "pred_label": "__label__POS", "pred_score_pos": 0.6399041414260864}
{"content": "All persons residing in the Virgin Islands are encouraged to participate in the Territory’s COVID-19 Survey to assist Public Health officials in determining the public’s knowledge and understanding about the disease.\nThe survey, which is available online at https://www.surveymonkey.com/r/BVI_COVID-19_KAP, takes approximately 10 minutes to complete and is anonymous and confidential.\nThe questionnaire was designed by Chief Epidemiologist Harmony Brewley-Massiah who stated that the survey is a Knowledge, Attitudes and Practices (KAP) study to capture what is known, what is thought, what is done in relation to a specific topic, in this case, the Coronavirus COVID-19.\nMrs. Brewley-Massiah explained that establishing a baseline for public understanding is important for containing the virus.\nShe said, “Once we identify where the gaps are when it comes to what people have learned so far about the Coronavirus COVID-19 and what preventative actions they’re practicing in their daily lives, we can effectively tailor our efforts to prevent it from spreading in our community.”\nResponses will be analysed by the Ministry of Health and Social Development, and the analysis will be shared with the BVI community.\nPersons who are experiencing symptoms of COVID-19 or who think they may have been exposed to the virus should stay at home and call the COVID-19 medical hotline at 852-7650.", "pred_label": "__label__POS", "pred_score_pos": 0.7641394138336182}
{"content": "New Jersey has stringent laws punishing those charged with drug offenses. If you or a loved one was charged with the possession of a controlled substance, you need assistance from a skilled Atlantic City criminal defense attorney. Facing New Jersey’s criminal justice system after being arrested and charged with a crime can be a scary experience. However, we can help you understand what to expect from your case moving forward. You may wonder if being in possession of a controlled substance such as Xanax can lead to an automatic conviction in New Jersey. Our Atlantic City drug charge defense attorneys from the Law Offices of John J. Zarych explain.\nWill I Go to Jail for Having Xanax Without a Prescription in New Jersey?\nMany people get confused and falsely believe they will not face criminal charges for possessing or otherwise consuming a substance that is commonly prescribed by physicians. However, you can quickly hit a wall if you get caught with a controlled substance without a valid prescription from a board-certified physician. Put simply, if you get caught with Xanax and don’t have a valid prescription for its use, you can face severe criminal penalties. Atlantic City criminal lawyer for Xanax possession John Zarych can help you fight these charges.\nAccording to N.J.S.A. § 2C:35-10, it is illegal to actually or constructively obtain or possess a controlled substance without a valid medical prescription. This legal statute is clear and leaves very little to interpretation. In New Jersey, only those compliant with this statute are allowed to possess and use a controlled substance, such as Xanax.\nIf you are found in possession or control of Xanax without a valid medical prescription, you can face prison time and steep fines. For instance, if you forged a prescription to get Xanax, you can face a third-degree indictable crime charge. This specific type of crime is serious, and if convicted, you can face up to five years in prison and up to $100,000 in fines. If this has happened to you or a loved one, contact an experienced prescription drug charges defense lawyer.\nHowever, your criminal charges can increase if you are found guilty of selling and distributing Xanax. For instance, if you are found with Xanax in excess of 100 tablets, caplets, or pills, you can be charged with a second-degree indictable crime. If convicted, you can face up to ten years in prison and up to $300,000 in criminal fines.\nBeing charged and convicted of possessing, selling, or distributing Xanax without a valid license can lead to severe criminal consequences. It is essential to hire an experienced New Jersey drug charges defense lawyer who can help you during this time.\nHow Can I Defend Against Charges for Having Xanax without a Prescription in New Jersey?\nYou can defend yourself against your drug charges involving Xanax, despite their potential consequences. Many times, defense strategies available to defendants often involve the circumstances surrounding your arrest and charges. It is essential to keep in mind that you have constitutional rights that should be respected at all times.\nSuppose you were stopped by the police, which led to a discovery of Xanax without prescription. In these circumstances, everything from your stop to your search and seizure must be done following the constitutional mandate. According to the Fourth Amendment of the U.S. Constitution, all citizens – including criminal suspects – are protected against unreasonable or otherwise illegal searches and seizures.\nBased on this principle, there are things the police can and cannot do during an investigation. A police officer can engage in a “reasonable” search if they have probable cause to believe you were in possession of Xanax without a valid prescription. A police officer cannot stop you and search your entire vehicle looking for drugs without probable cause. In order to search your vehicle, a police officer must have seen the illegal drug in plain sight, gathered some other articulable facts that support probable cause, or gone to court to get a search warrant. Any evidence obtained in violation of your constitutional rights cannot be admitted as evidence against you.\nIn your case, the prosecutor must be able to prove beyond a reasonable doubt that you committed the crime for which you are charged. If they cannot meet their burden of proof, you cannot be convicted. However, it is necessary to have a competent, skilled, and experienced criminal defense attorney by your side.\nAre There Other Alternatives to Jail Time for Having Xanax without a Valid Prescription in N.J.?\nAs we mentioned, drug charges in New Jersey can lead to prison and hefty criminal fines. However, you may have an alternative option to incarceration. New Jersey’s Pretrial Intervention Program (PTI) acts as a diversion program where offenders avoid jail by participating in rehabilitation. While this program is a potential option, it is critical to understand that it is not available for all types of crimes. Typically, violent offenders are not eligible for PTI, and they will have to go through the ordinary course of prosecution.\nThe goal of PTI is to assist participants and help them avoid future drug incidences. To achieve this, PTI offers a structured treatment program to help participants avoid falling back on old habits. The most significant upside of this type of program is that it allows the defendant to avoid jail and avoid a criminal conviction record. As you may know, having a criminal record can have lasting, severe consequences. It is absolutely critical to talk to your lawyer and see whether you can qualify for this program and avoid a criminal conviction.\nCriminal Defense Attorney Offering Free Consultations in New Jersey\nIf you or a loved one is facing criminal charges for having Xanax without a valid prescription in New Jersey, you need to act quickly. Facing New Jersey’s criminal justice system for drug charges can be overwhelming and challenging. However, you are innocent until proven otherwise. You can fight against your charges with our Atlantic City criminal defense attorneys. At the Law Offices of John J. Zarych, we can fight aggressively and strategically to defend and uphold your rights as a defendant. To learn more about all of our services in a free, confidential consultation, call our law offices today at (609) 616-4956.", "pred_label": "__label__POS", "pred_score_pos": 0.9091446995735168}
{"content": "Exosomes, derived from various biofluids, may serve as potential biomarkers for cancer early detection. Nevertheless, exosome clinical translation remains challenging due to the lack of reliable isolation and detection methods. Researchers from Wenzhou Medical University present a novel integrated microfluidic device specifically designed for isolation and in-situ detection of lung cancer-specific exosomes collected from patient’s urine. The new device has been fabricated using polymethyl methacrylate (PMMA) and a nanoporous gold (Au) nanocluster membrane modified with the capture antibody. The second antibody-conjugated Au nanorod probe was then loaded to identify and quantify lung cancer-specific exosomes using a dark field microscope. AuNC-Exosome-AuR complex produces a significant scattering wavelength shift and an improved scattering intensity due to resonance Rayleigh scattering, which enables the ultrasensitive detection of exosomes with a LOD below 1000 particles/mL. The proteomic analysis revealed that the high-purity exosomes has been isolated by the device. The researchers then validated this method with 500 μL urine samples from lung cancer patients and controls, which showed great promise for differentiating early-stage lung cancer patients from healthy individuals. Taken together, the presented method is fast and ultrasensitive and can be easily adapted for the isolation and detection of cancer specific exosomes from other malignant tumors.\nAn integrative microfluidic device for isolation and ultrasensitive detection of lung cancer-specific exosomes from patient urine. Biosensors and Bioelectronics[Epub ahead of print]. [abstract]", "pred_label": "__label__POS", "pred_score_pos": 0.9984394311904907}
{"content": "GEM&L aims to contribute to the academic study of language in organizations, from the management of cultural differences to the understanding and sense-making structured by language. GEM&L’s initiatives include\naffirming the place of language and languages in management research and education encouraging reflection on the role of language and cultural studies teachers from an interdisciplinary perspective facilitating contact and collaboration among researchers, teachers, and professionals with an interest in this field.\nThe association hosts an annual international conference with double-blind peer-reviewed selection process and supports its members, including doctoral students, by promoting and assisting them in their research activities and circulating information on academic journals and conferences.", "pred_label": "__label__POS", "pred_score_pos": 0.9581388831138611}
{"content": "Five growers worked with the Nebraska On-Farm Research Network in 2014 to assess the use of cover crops for their farming operations. Specifically, these producers were concerned with the impact of cover crops on the yield of the subsequent cash crop. The cover crop mixtures and cash crops varied by location. The results of these five studies are explored here, moving from west to east across the state.", "pred_label": "__label__POS", "pred_score_pos": 0.5151206254959106}
{"content": "Abstract\nWithin the Australian construction industry, rework has been identified as a significant factor that contributes to cost increases and project completion delays. It has been suggested that a major cause of rework relates to the quality of contract documentation that is produced by design consultants and that higher fees paid to consultants would result in improved contract documentation quality. Using a questionnaire survey, this paper determines the key contract documentation variables that influenced rework costs in 161 construction projects. Evidence from the findings presented form the basis of practical suggestions made for improving the management of the design process and the production of contract documentation in projects. However, no significant relationship between contract documentation and rework could be established from the findings presented.", "pred_label": "__label__POS", "pred_score_pos": 0.9234971404075623}
{"content": "Abstract\nWe investigate how the strictness of a requirement to consult on potential client fraud affects auditors' propensity to consult with firm experts. We consider two specific forms of guidance about fraud consultations: (1) strict, i.e., mandatory and binding; and (2) lenient, i.e., advisory and non-binding. We predict that a strict consultation requirement will lead to greater propensity to consult, particularly under certain client- and engagement-related conditions. Results from two experiments with 163 Dutch audit managers and partners demonstrate that consultation propensity is higher under a strict consultation requirement, but only when underlying fraud risk is high. The strictness effect is also greater under tight versus relaxed time pressure. Further, a strict standard increases auditors' perceived probability that a fraud indicator exists. Overall, we demonstrate that the formulation of a standard can have the desired effect on the judgments of auditors while also creating unexpected incentives that may influence auditor judgments.", "pred_label": "__label__POS", "pred_score_pos": 0.8775599002838135}
{"content": "Interoperability is a key trend in the field of digital healthcare. Discover what interoperability is, why it is important to medical fields such as dermatology, and learn about how intelligent dermatology such as DermEngine is developing integration tools to create a centralized platform.\nAs technology develops, the need for electronic medical records (EMR) is continues to soar. The goal of EMRs is to keep a digital record of patients’ medical history in order to provide centralized, secure, accessible care. Discover what the latest dermatology EMR software has to offer.\nTo combat the rising rates of skin cancer, medical professionals must be equipped with advanced dermoscopy tools designed to optimize and enhance their practice.", "pred_label": "__label__POS", "pred_score_pos": 0.6227490901947021}
{"content": "Reaching the ambitious EU 2050 climate neutrality goal means that steep reductions of carbon dioxide (CO\n2) are necessary, along with further minimisation of methane emissions. With the latter accounting for 10% of all greenhouse gases (GHG) emissions in the EU in 2017, energy-related methane emissions have been identified as a priority under the European Green Deal.\nGasNaturally Members are taking decisive steps to better assess, document and reduce methane emissions, and support the European Commission in developing a Methane Strategy. However, achieving these reductions, in the shortest possible time and in the most cost-efficient manner, will directly depend on getting certain technicalities right and using appropriate policy tools. The European Commission should incentivise early action on methane emissions reduction, boost innovation and ensure flexibility for new technologies and practices.\nThe EU gas industry is making significant progress in reducing methane emissions.\nBased on available data, the gas industry accounts for around 5% of the overall EU methane emissions (approximately 0.6 % of the total EU GHG emissions). These originate from fugitive emissions (unintentional leaks from equipment or components – most challenging to quantify), venting (intentional releases due to safety considerations, equipment design or maintenance/operational procedures) and incomplete combustion.\nThe good news is that the EU gas industry can and is taking meaningful steps to reduce methane emissions. Between 1990 and 2017, industry initiatives have already led to a 56% reduction in fugitive methane emissions from natural gas activities. However, while methane emissions can be detected (e.g. using infra-red, laser cameras, spectrometer technology), they are more difficult to accurately measure. Therefore, improving the accuracy of the data is a key priority in order to continue reducing emissions.\nA 2019 report on methane coordinated by GasNaturally Members GIE and MARCOGAZ highlights the challenges as well as the progress made by the industry on identifying, detecting, quantifying, reporting and verifying emissions along the value chain, while continuously improving the accuracy of data through progress in science and technology. At any given time, there are several projects around the world, at various stages of completion, that continue to contribute to our understanding of methane emissions sources and approaches to mitigation.\nAn example is the 2017 launch of the Methane Guiding Principles (MGPs), developed by a coalition of industry, international institutions, NGOs and academics, which is supported by a majority of GasNaturally Members. Focusing on five priority areas, one of the actions undertaken by the coalition is the development of a methane common reporting template. This initiative complements and reinforces others, such as the Oil & Gas Climate Initiative and the Climate and Clean Air Coalition – Oil and Gas Methane Partnership.\nTo continue the progress in reducing methane emissions, GIE and MARCOGAZ, in collaboration with representatives from the entire gas value chain, developed an Action Plan which was launched in January 2020. Consisting of over 50 concrete actions, the Action Plan aims at ensuring accuracy and harmonisation, developing cost-effective and flexible policies, continuously improving and stimulating innovation, taking a balanced and holistic approach and engaging all sectors and non-EU stakeholders.\nThe EU should incentivise early action on methane emissions reduction and stimulate innovation.\nGasNaturally supports the European Commission in developing an ambitious methane strategy, that incentivises early action, drives performance improvements, facilitates proper enforcement, stimulates innovation and is flexible to accommodate new technologies and practices. Given the technical challenges related to methane emissions in the gas industry, we stand ready to contribute with evidence-based insights from ongoing research projects, which is particularly critical for the development of Measurement, Reporting and Verification (MRV) standards that are currently under discussion.\nOn a more general note, the success of the European Green Deal in general and of progress on methane in particular will strongly depend on a robust innovation agenda. Gas will continue to play a key role in the EU’s energy landscape, which means that creating incentives to promote innovation in tackling emissions across the European gas supply chain should be among the priorities of the EU’s agenda on decarbonisation.", "pred_label": "__label__POS", "pred_score_pos": 0.9609267711639404}
{"content": "Unstable soil can expand or shift with high moisture or extreme temperature changes, leading to significant variations in pressure that can make foundations tilt, buckle, heave or crack. When a foundation isn’t set properly, these problems become even worse. A sagging foundation is a serious concern for your household's overall safety. Foundation cracks, cracks in window/door frames, and uneven floors act both as side effects and indicators of a larger problem. Over time, severe damage can come from sagging foundations, costing more in repairs and leaving homeowners with precarious living conditions.\nThere are options for repairing sagging foundations, depending on the exact nature of your home, the construction of your foundation, and the ground underneath and alongside it. If the soil underneath can be stabilized, possibly with high-pressure grouting, that might be enough. If it's a helical pier, push pier, or wall brace – three of the most common solutions – restoring the integrity of your foundation protects your investment in your home. If compact soil isn’t too deep and the structure of your home isn’t too heavy, helical piers are a common repair option. In the case of larger, heavier buildings or when load-bearing soil is deeper, push piers are often used. In some cases, a galvanized steel wall brace anchored vertically might be enough. Rely on the experts at Thrasher to find the best solution for you and to guarantee you will be satisfied with the results.", "pred_label": "__label__POS", "pred_score_pos": 0.9479627013206482}
{"content": "Fill out the form and a member of the InfoSum team will get in touch to arrange a demo of the world’s first Unified Data Platform.\nNever miss an opportunity to deliver relevant and timely marketing. Streamlined legal and privacy review and cutting-edge technology deliver accelerated data onboarding.Speed\nInstantly measure the intersection between your first-party data and our best-of-breed activation partners. Empowering transparent decision making when onboarding your data.Platform\nDeliver marketing at an unrivalled scale with no reliance on a single form of identity. Enabling you to maximise match rates across any number of channels.Identity\nLegacy data onboarding solutions required customer data to be moved into a third-party environment, where the data is ‘flattened’ to their proprietary third-party ID.\nInfoSum’s data onboarding solution is built on a decentralised identity infrastructure that removes the need to share Personal Data with a third-party.\nIdentities are matched deterministically either using the unique identifiers that already exist in each dataset, or via an ‘identity bridge’ with one of InfoSum’s trusted identity partners.\nWith third-party cookies and other third-party identifiers under increased scrutiny from regulators and now actively blocked by all the major web browsers, Personal Data (PII), such as an email address, is becoming an increasingly important identifier. However, using Personal Data to match identities between data sets, requires an increased focus on privacy and security.\nInfoSum provides a privacy-by-design data clean room environment to deterministically match identifiers on Personal Data, providing a cookieless solution that enables advertisers to utilise their first-party data within the advertising ecosystem.\nInfoSum doesn’t rely on a single form of identity. This allows us to remain completely identity agnostic and not be constrained by the limits of what one identity or identifier can support.\nBy taking this approach, advertisers can match their first-party customer data against any addressable audience across any media channel. This unlocks the ability to plan holistic marketing campaigns across digital, mobile audio and connected TV to unlock true omnichannel marketing.\nPrivacy has been built into every element of InfoSum’s platform, delivering a truly privacy-by-design data onboarding solution. By utilising a federated architecture, data can remain decentralised and in control of the data owner, while also enabling identities to be matched and analysis conducted - all without sharing any of the underlying data.\nAll results are at an aggregated statistical level and are designed to drive data insights, planning and measurement. Additionally, differential privacy techniques are applied to all results generated, ensuring that no single individual can ever be identified through the platform.\nInfoSum remains completely agnostic, enabling brands to activate across their chosen identity partner or combination of partners.\nData is uploaded to a dedicated instance, running on secure cloud infrastructure, known as a Bunker. Only you have access to this, and the data never leaves.\nWhere a relationship exists with an identity partner, they will need to send you a permission to use their identity graph in your analysis.\nThrough the connections tab, you can instantly see the intersection between your data and the identity partner’s identity graph.\nFurther analysis can be conducted of the audience, and segments created.\nOnce your audience segment has been created, this can be sent for direct activation via the identity partner.\nWhen this happens, only the identity partners own unique IDs are sent, ensuring your data is never shared.\nWe don’t hold any data. We provide the identity infrastructure to power a decentralised ecosystem.\nFederated technology keeps your data in its own unique Bunker, that only you can access.\nYou remain in control of who can analyse your data. This never grants access to the raw data.\nOffline data is matched to online identifiers without sharing the data with a third-party identity vendor.\nDownload our case study to find out how a national supermarket was able to onboard their first-party data, enabling them to deliver relevant and timely advertising to their loyalty cardholders.\nDeliver more relevant and timely marketing faster and at greater scale than ever before, with our end-to-end data onboarding solution.", "pred_label": "__label__POS", "pred_score_pos": 0.8696033954620361}
{"content": "Digital technologies, in the form of social contact tracing apps, look like they are going to play an important role in tackling the Covid-19 crisis. This intervention argues that while liberating us in the short-term, such technologies could contribute to the growing power and influence of surveillance capitalism over our lives.", "pred_label": "__label__POS", "pred_score_pos": 0.8072342872619629}
{"content": "The global rating agency Standard & Poor's (S&P), on Wednesday, affirmed its 'BBB-' rating with a stable outlook. The development comes within days of Moody's downgrading India to one notch above junk status.\nThe ratings agency affirmed its 'BBB-' long-term and 'A-3' short-term unsolicited foreign and local currency sovereign credit ratings on India. The outlook on the long-term rating is stable.\nIndia's rating reflects its above-average real GDP growth, sound external profile, and evolving monetary settings. India's strong democratic institutions promote policy stability and compromise, and also underpin the ratings, S&P said, explaining the rationale for its action.\nThese strengths are balanced against vulnerabilities stemming from the country's low per capita income and consistently elevated fiscal deficits that contribute to high general government debt, net of liquid assets. India's economy will contract in the fiscal year 2021, largely owing to the impact of the COVID-19 pandemic, it added.\n'We forecast a 5.0% decline in real GDP growth, which would be the worst economic performance in recent history,' S&P said in a statement.\nThe global economic downturn resulting from the pandemic, along with strict domestic measures aimed at containing the spread of the local epidemic, are hitting the economy hard, and will likely result in a significant fall in activity in the first quarter of this fiscal year.\nIndia's economy is likely to achieve a strong recovery following the deep contraction in this fiscal year; we forecast real GDP growth at 8.5% in fiscal 2022, the agency said.\nProductive capacity has been severely disrupted during this period, and millions of workers have left their jobs to return home, sometimes crossing the country to do so. India's labor markets have therefore weakened dramatically, and may take some time to heal, it added.", "pred_label": "__label__POS", "pred_score_pos": 0.9698505401611328}
{"content": "Marking territory of their own is a crucial element of bear interaction. Bears take a lot of time and effort to place appropriate markings and stake their turf. They leave scratches and gouges, augmented by olfactory urine markings, on the trunks of large, stand-alone trees or big, unusually shaped stumps. Thus they proclaim loud and clear: ‘This is my territory! Do not trespass or you’ll have me to deal with!’ By doing so, they delineate their ‘home turf’ where they find food, shelter and mating partners. This sends a signal to weaker or less confident specimens to seek other habitats, thus reducing the risk of a direct clash between two bears.\nVideo:\nPhoto Gallery:", "pred_label": "__label__POS", "pred_score_pos": 0.6421705484390259}
{"content": "Abstract Scope Aluminothermic reduction of metal oxides commonly known as the thermite process has remained unchanged since its inception in 1893. This reduction process is highly exothermic and has an activation temperature above the melting point of Al at around 660⁰C, with the reactants reaching up to 2000⁰C. We present a variant of the thermite process capable of reducing metal oxides at low temperatures in the range 50⁰C to 600⁰C. Results will be presented for reduction of ZnO, CuO, SnO2, Sb2O5, Fe2O3, NiO, V2O3, Ta2O5 and WO3 with yields up to more than 99%. For most of those oxides, the by-products can be separated from the metal powder products by washing in water. This novel reaction route enables a new simple pathway for reducing metal oxides through solid-solid reactions, directly leading to metal and metal alloy powders and allowing to conserve morphological features from the starting precursors.", "pred_label": "__label__POS", "pred_score_pos": 0.8432598114013672}
{"content": "Tuesday, 13 August 2019\nIn a brand-new ranking dominated by US genetics, the Danish-bred Viking bull,\nVH Balisto Brook, rises to the top, graduating from the young sire genomic ranking with early milking daughters.\nPublished today (13 August 2019) by AHDB Dairy, Brook’s Profitable Lifetime Index (PLI) of £794 is the highest of the available proven bulls and reflects the high fat and protein percentages in his Predicted Transmitting Ability (PTA), at +0.23% and +0.12% respectively. He combines this with breed-leading udder health figures (-40 SCC, -5 Mastitis), reflecting the significant emphasis placed on these traits over many years in the Nordic countries.\nAlso graduating from the genomic young sire ranking is the new entry in second place,\nBomaz AltaTopshot (PLI £766). This Cogent Supershot son transmits high production figures with 1,187kg milk and 71.2kg combined fat and protein.\nThe familiar name of\nCo-op Robust Cabriolet features in third place, now with 684 UK daughters contributing to his production figures. He excels in calf survival (+4.2), Lameness Advantage (+4.2) and maintenance index (-21), earning him a PLI of £755 at a reliability of 95%, the highest in the top 10.\nFormer number one sire,\nLarcrest Commend, now ranks fourth in this elite group of bulls, with a PLI of £752. With over 100 UK daughters, he transmits high milk solids at 0.20% fat and 0.18% protein.\nNew in fifth place is the Mr Mogul Delta son,\nSiemers Bloomfield, a high daughter Fertility Index bull (+13.1) with good calf survival (+4.1) and long daughter lifespans (+0.7). His PLI is £749 and Type Merit of +2.6 is the second highest in the top 10.\nSixth ranking\nView-Home Littlerock maintains a top-10 position with a PLI of £719, as his UK daughter numbers rise to 124.\nGerman-bred\nMocon retains seventh position (PLI £715) while eighth ranking De-Su 12147 Allstar is propelled into the top 10 as 111 more UK milking daughters contribute to his PTAs. This son of Balisto (one of four in the top 10) features a massive 40.3kg protein, to help earn him a PLI of £714.\nNinth placed\nCookiecutter Harper (PLI £713) is a former top 10 sire, while the Mogul son, EDG Rubicon rounds off the top 10. A massive 52.6kg fat (78.4kg fat plus protein) helps to earn him a PLI of £709. With +3.26 points for type, he is also the highest Type Merit sire in the top 10.\nJust outside the daughter-proven top 10, newcomer,\nAOT Silver Helix may cause a stir, with a breed-leading 88.2kg fat plus protein, while some serious daughter fertility improvements can be expected from the highest FI bulls in the top 25. These bulls – Teemar Shamrock Alphabet (PLI £682) and S-S-I Mogul Multiply (PLI £676) – have Fertility Indexes of +19.6 and +19.1 respectively.\nCommenting on the proven bulls, Marco Winters, head of animal genetics for AHDB Dairy, says: “Every one of these daughter-proven bulls has graduated at some point from the young sire genomic ranking, each bull helping to build confidence in the UK and international dairy sire proving systems.\n“Producers who choose to keep a few, high-ranking, daughter-proven bulls amongst their service sires can do so in the knowledge that these sires have a reliable track record. But they also serve as a reminder that genomic evaluations are proving their value, as one tranche of young sires follows the next into the proven rankings.”", "pred_label": "__label__POS", "pred_score_pos": 0.6133028268814087}
{"content": "In this modern era of globalisation where geographical boundaries are no longer a limitation, with shrinking lead times and increasing speed of business, organisations have a greater need for efficient supply chains than ever before.\nIn this blog I will explore the collaboration features allowing organisations to plan their supply chains effectively and efficiently.Read Article", "pred_label": "__label__POS", "pred_score_pos": 0.990196943283081}
{"content": "Number of households privately renting has doubled in 30 years\nThe number of households renting from private landlords has more than doubled in the past thirty years.\nSome 22% of households now rent privately, according to a report from think tank ResPublica.\nIn 1985 the figure was just 9%.\nConversely, the number of households renting from public landlords has fallen dramatically during the same period.\nIn 1985, 30% of households rented from public landlords, a figure which has since fallen to 9%.\nThe report also reveals that owner-occupancy levels are the same now as they were thirty years ago.\nIn 1985, 61% of households owned their home, the same proportion as today, ResPublica reports.\nThis is despite a significant drop in the early 2000s.\nEarlier this year, the annual English Housing Survey revealed that in 2013/2014 19% of households rented privately, while owner-occupiers accounted for 63% of all households.", "pred_label": "__label__POS", "pred_score_pos": 0.9427598714828491}
{"content": "Bernard Gauthier\n01.06.1996\nThis article assesses the performance of small-scale manufacturing enterprises during the process of structural adjustment in Cameroon. It seeks to determine whether all segments of the industrial sector have been similarly affected by down-scaling, or whether some categories have adapted better to the liberalization of trade and regulatory parameters. Survey results show that a large segment of the manufacturing sector, mostly larger-scale units originally established within a highly subsidized and protected economic environment, is experiencing difficulty in adapting to liberalization measures. On the other hand, small-scale enterprises, which did not benefit from the same kind of protection as their larger counterparts, are experiencing growth. However, if current trends are maintained, the vitality of the small-scale sector will probably not be sufficient to prevent deindustrialization of the country.", "pred_label": "__label__POS", "pred_score_pos": 0.5278568267822266}
{"content": "The Federal House of Commons Standing Committee on Health has initiated a study of Lesbian, Gay, Bisexual, Transgender, Queer and Two-Spirit (LGBTQ2) health in Canada. This includes a review of the challenges LGBTQ2 communities face in accessing health services (physical, mental and sexual) across the country. As part of this, the committee invited the public to make written submissions.\nWith contributions from two BLG lawyers, Daniel GirlandoandJohn McIntyre, and other lawyers across Canada, the Canadian Bar Association's Sexual Orientation and Gender Identity Community Section and Health Law Section jointly made recommendations on five topics, briefly summarized below and available in full on the CBA website.\nConversion therapy— institute clear criminal and taxation sanctions for those individuals and organizations offering conversion therapy, as the current bans on public funding for conversion therapy in Manitoba, Ontario, Nova Scotia and Vancouver are not enough to protect children and vulnerable adults; Access to pre-exposure prophylaxis (PrEP) treatments— study the cross-Canada public coverage of PrEP (a prophylactic drug linked to a decline in new HIV infections) as part of the federal government's impending national pharmacare plan; Intersex surgery on infants and children — institute criminal prohibitions on genital normalizing surgeries on children with intersex variations until the child can meaningfully participate in the decision (except where there is an immediate risk to the child's health); Eligibility to donate blood— immediately implement the recommendation to reduce the restriction on donations from men who have sex with men to three months after their last sexual contact (instead of one year) and continue to review based on new research and recommendations [note: the Minister of Health announced this change on May 8, 2019]; and Trans health— increase sensitivity and competence training in trans health care issues for providers and fund training for gender confirming surgeries.", "pred_label": "__label__POS", "pred_score_pos": 0.535519003868103}
{"content": "COVID-19 could affect CPE reporting deadlines.\nThe National Association of State Boards of Accountancy (NASBA) on Tuesday announced that it was recommending state boards of accountancy across the country extend their CPE-completion deadlines to accommodate accountants affected by COVID-19 disruptions. This development comes on the heels of federal, state, and local governments implementing a number of public safety measures designed to reduce the spread of the coronavirus.\nNASBA recommended extending current CPE deadlines to October 31, 2020. “If a CPA’s reporting period ended on March 31, 2020, the licensee would have until October 31, 2020, to complete the CPE requirements for that reporting period,” NASBA explained. “Similarly, if a CPA’s reporting period ended on June 30, 2020, the licensee would have until October 31, 2020, to complete the required CPE.”\nAs an advocacy and advisory group for state boards of accountancy, NASBA notes in the press release that it does not hold regulatory authority over those bodies. While individual boards of accountancy will make their own determinations concerning CPE deadlines for current and pending licensees, NASBA committed to cataloguing which states extend their CPE deadlines.\nIn the announcement, NASBA noted that their office—located in Nashville, TN—has already transitioned to remote work, underscoring the challenges faced by businesses across the country.\nSource: “CPE Reporting Grace Period Due to COVID-19 – NASBA Recommendations”", "pred_label": "__label__POS", "pred_score_pos": 0.9546884894371033}
{"content": "A legally mandated, multilateral, mutual assistance scheme for coping with natural disasters has long eluded the community of nations. Instead, ‘disasters without borders’ are managed through a non-binding international humanitarian network. Below, John Hannigan shows that this arrangement has become a victim of the changing geopolitics of security, international development and complex emergencies, and suggests that in its place we must expect a realigned global policy field of natural disasters.\nOn 15 October, 2013, a 7.2-magnitude earthquake, the deadliest in 23 years, struck the central Philippine islands of Cebu and Bohal. The quake seriously damaged churches dating from Spanish colonial times, displaced 344,000 residents, and killed more than two hundred. Within ten days, a ‘“Bohol Earthquake Action Plan’” was up and circulating on ReliefWeb, an information portal for the global humanitarian community administered by the United Nations Office for the Coordination of Humanitarian Affairs. Among those seeking $US 46 million under the Plan are the International Labour Organization, Habitat for Humanity and World Vision. This underscores the widely shared notion of ‘disasters without borders’\n1: what happens in one part of the globe resonates elsewhere, socially, economically and politically.\nIn this article, I will outline how a humanitarian aid model for dealing with disasters became widely accepted in international affairs during the 1970s and 1980s; faltered in the 1990s; and is currently being challenged by a new approach to disaster management wherein risk management and insurance logic replace humanitarian concern as guiding principles.", "pred_label": "__label__POS", "pred_score_pos": 0.6783424615859985}
{"content": "The world is facing increased levels of humanitarian need with many people being forced to leave their homes. This displacement may occur within their own country or across borders. For increasing numbers of displaced people the reasons for leaving include for their own safety due to war and violence or from environmental disasters. The vulnerabilities these people might face may be intensified by language barriers, social isolation and limited awareness of where to seek help. Understanding the underlying issues, conflicts and pressures which cause migrations may allow developed nations to help prevent them and ameliorate the consequences when they occur.", "pred_label": "__label__POS", "pred_score_pos": 0.7886505722999573}
{"content": "This paper brings together evidence from various data sources and the most recent studies to describe what we know so far about the impacts of the COVID‐19 crisis on inequalities across several key domains of life, including employment and ability to earn, family life and health. We show how these new fissures interact with existing inequalities along various key dimensions, including socio‐economic status, education, age, gender, ethnicity and geography. We find that the deep underlying inequalities and policy challenges that we already had are crucial in understanding the complex impacts of the pandemic itself and our response to it, and that the crisis does in itself have the potential to exacerbate some of these pre‐existing inequalities fairly directly. Moreover, it seems likely that the current crisis will leave legacies that will impact inequalities in the long term. These possibilities are not all disequalising, but many are.", "pred_label": "__label__POS", "pred_score_pos": 0.50527024269104}
{"content": "Abstract\nCircadian rhythm sleep disorders are characterized by a desynchronization between the intrinsic circadian clock and the extrinsic light-dark cycle. As a result, symptoms of excessive sleepiness and insomnia can lead to significant impairment of daytime functioning. The six currently recognized circadian rhythm sleep disorders may involve either a primary abnormality of the patient's circadian clock or a normal functioning circadian clock with a newly changed external physical environment. Both light therapy and melatonin can be used strategically to realign the patient's endogenous sleep-wake cycle with the preferred sleep-wake schedule. Continued research of the underlying pathophysiology of circadian rhythm sleep disorders may lead to improved treatment strategies.\nASJC Scopus subject areas Psychiatry and Mental health", "pred_label": "__label__POS", "pred_score_pos": 0.9827068448066711}
{"content": "11. Gëzim Visoka (2016), ‘Peace is what we make of it? Peace-shaping events and ‘non-events”, Peacebuilding , 4(1): 54-70.\nAttempts to build peace often fail to achieve the intended outcomes. Such endeavours often lead to unintended effects shaped by multiple factors, events, and actors. This raises the question: if the intentional actions that constitute peace processes do not succeed in bringing about their intended impact, what actually shapes peace? This article argues that peace is shaped by events and non-events within and beyond the liberal peace architecture, as well as being determined by local agents who are not directly or intentionally involved in peacebuilding endeavours. While the success of liberal peace is measured based on the generalised assemblage of selected events, the unintended, unanticipated, and unprevented events that emerge as consequences arising from liberal peace actions are reduced to non-events to minimise responsibility. However, the power of these ignored non-events that occur at local institutional, public, and everyday levels have been crucial to shaping the nature, process, duration, and politics of peacebuilding. Unpacking the politicisation of events and non-events reveals that peace is what we make of it rather than a true reflection of the complex reality in conflict-affected societies. To substantiate this conceptualisation of abstruse peace, this article draws on examples from numerous events and non-events as experienced in Bosnia and Herzegovina, Kosovo, and Timor-Leste.", "pred_label": "__label__POS", "pred_score_pos": 0.9999644160270691}
{"content": "Infant Room Welcome to the Infant Room! Ages: 6 weeks through transition 14-16 months\nJMLC understands and practices the importance of attachment. Research indicates that secure attachments and healthy parent child relationships are associated with psychosocial health.\nTherefore, insecure attachments result in a wide range of difficulties for the child such as disassociation, unhealthy bonds, depression, fears, poor self regulation, and feelings of isolation.\nPoor attachment can be caused by a variety of situations including changes in child care placement. JMLC is dedicated to bonding with infants to promote healthy childhood.\nJMLC accepts infants at 6 weeks old and the infant only transitions to the transition classroom when the child is secure and ready for the next step of development. The child transitions into the next classroom based on developmental abilities rather than chronological age.", "pred_label": "__label__POS", "pred_score_pos": 0.677414059638977}
{"content": "Uncoated fabrics provide the next level of heat insulation and light absorption. Uncoated fabrics constitute the vast majority of fabrics used in curtains, and are composed of a tightly woven fabric, most typically a cotton/polyester blend, which is mostly opaque when viewed in ambient light. Uncoated fabrics provide a reasonable level of heat insulation due to the tight weave of the fabric. However, the fabric itself is typically not thick enough to completely absorb strong light sources. As a result, when curtains made from uncoated fabrics are closed in an attempt to block out direct sunlight, light will still be visible through the curtain.", "pred_label": "__label__POS", "pred_score_pos": 0.5942580699920654}
{"content": "Rethinking Cancer UCL Cancer Domain Symposium Monday13 May 2019 UCL Institute of Education Registrationfor the inaugural UCL Cancer Domain Symposium is open\nCancer remains one of the major causes of morbidity and premature death worldwide; one in two people in the UK born after 1960 will be diagnosed with some form of cancer during their lifetime. UCL has a proud track record in addressing the societal, technical, and health challenges of cancer and in exploring its underling biology.\nThis symposium, organised by the UCL Cancer Domain, invites our broad community to assemble for the first time at scale to consider challenges and opportunities in cancer research, prevention and treatment, from biological, clinical, technical, economic and societal perspectives. The event showcases our distinctive multidisciplinary expertise and features interactive discussion sessions with our speakers and panels. Talks are scheduled on the following themes:\nCancer evolution: can we beat Nature? Cancer detection: the earlier the better? The cancer treatment revolution and how we afford it\nWe aredelighted to announce that\nProfessor Charles Swanton (UCL CancerInstitute and Francis Crick Institute) and Professor Mariana Mazzucato(UCL Institute for Innovation and Public Purpose) will deliver the keynote lecturesat this event. Register your place here: https://ucl-cancer-domain-symposium-2019.eventbrite.com\nJoin the conversation by tweeting us @UCL_SLMS using the hashtag #UCLCancerDomain", "pred_label": "__label__POS", "pred_score_pos": 0.8247244358062744}
{"content": "In the aftermath of India’s COVID-19 lockdown, specific groups have emerged as particularly vulnerable to the economic and social consequences of this preventive action. One key group among these are the homeless, who are forced to occupy public spaces and utilise shared facilities, face hunger and are subject to reprisals for violating social distancing. This article outlines Mumbai’s action plan for protecting its 2 lakh homeless from being exposed to Covid-19, and addressing their needs in a time of crisis.\nImage by Alvin Decena on Unsplash", "pred_label": "__label__POS", "pred_score_pos": 0.9983742833137512}
{"content": "[Researchers] have convincingly demonstrated that a subset of individuals in persistent vegetative states have meaningfully functioning minds — even as they remain completely unable to engage in other forms of volitional communication or behavior.\nThese discoveries have been largely heralded as good news by patients’ family members, neurologists, and advocacy groups. The logic runs like this: If individuals in pseudo-persistent vegetative states can communicate, even in this rudimentary manner, then there is justification for continued care and hope for further recovery.\nAs a bioethicist, I fear that this optimism may be blinding us to a genuine moral horror: being trapped in this way may be a form of unwitting medical torture.\n…\nSo what we are actually asked to decide, in cases where a patient’s wishes are unknown, is how to balance the prospect of contact via fMRI, or even recovery, against the possibility that the patient is trapped incommunicado in a persistent vegetative state and suffering psychological torment for years. That is no easy choice. But it is also not clear that the default should be preserving life, since it comes with the risk of perpetuating torture.", "pred_label": "__label__POS", "pred_score_pos": 0.5383797883987427}
{"content": "Seriphos\n$41.00\nResearch indicates that serine phosphate derivatives can reverse hypothalmic-pituitary resistance to cortisol feedback in cases of cortisol hypersecretion. It is also indicated in conditions of memory deficit. Indicated in cognitive decline, senile dementia and mild cases of Alzheimer’s disease. Seriphos is an Adaptogen and adrenal support formula that contains key nutrients for stress resiliency including phosphoserine, magnesium, calcium and phosphorus. This formula assists in balancing cortisol when levels are elevated due to acute or chronic stress.*\n******\nRecommended Dosage: Take 1 capsule daily with water 15 minutes before meal, or as directed by a healthcare practitioner. If pregnant, consult your physician before using this or any other product. - See Quantity: 100 Capsules Ingredients:\nOther ingredients: Gelatin capsule Milk, Soy, Egg, WheatDoes Not Contain: Storage: Store in a cool, dry place, not to exceed 77 F. Keep out of reach of children.", "pred_label": "__label__POS", "pred_score_pos": 0.9361628293991089}
{"content": "Each Vegetarian Capsule contains: Citicoline 250 mg Choline (bitartrate) 14 mg Non-medicinal ingredients: Microcrystalline cellulose, silicon dioxide. Capsule: Hypromellose. Contains no wheat, gluten, corn, nuts, dairy, soy, eggs, fish, shellfish or any animal byproducts. Dosage: Take 2 capsules daily with/without food, or as directed by a health care practitioner. Consult a health care practitioner for use beyond 3 months. AOR AOR, Citicoline 264mg 60 Vcaps\n$47.99\nAOR, Citicoline\nCiticoline plays a crucial role in the Kennedy pathway, by which the body synthesizes phosphatidylcholine (PC) and, ultimately, other phospholipids, such as phosphatidylserine (PS). By supporting the body’s synthesis of new phospholipids in youthful, physiological balance, Citicoline supports brain structure. Extensive research supports the role of Citicoline in supporting optimal cognitive function.", "pred_label": "__label__POS", "pred_score_pos": 0.847565233707428}
{"content": "It is easy to neglect your property, however one of the best ways to retain its value is to take care of it. That does mean fixing repairs when they are needed and carrying out regular maintenance checks.\nHere are our top tips on how to take care of your property all year round, from spring to winter. Spring External; - Clear gutters of leaves and debris to prevent issues caused by rainfall. - Check the roof for moss growth and loose or missing tiles. - Monitor the condition of exterior paintwork. - Make sure windows are cleaned regularly and check the condition of the glass and frames. - Maintain any decking, cleaning it annually to prevent a build-up of moss. - Clean any external decoration such as pots or stone work. Internal; - Pull furniture away from walls to air your living spaces, also check for damp and mould patches. - Open your windows to ventilate your home, preventing stale air and increased moisture. - Take down any curtains and blinds for a deep clean. - Check internal pipes for signs of leaks. - Check your loft for any signs of damage such as misaligned roof tiles and water ingress. Summer External; - Carry out exterior decorating jobs, the warmer weather will allow things to dry quicker. - Maintain your garden- trim ivy and other climbing plants to reduce the likelihood of damage and cut back any large trees and shrubs near the house. - Tackle any roof issues before the winter months draw in. Internal; - Get your boiler serviced and bleed your radiators in time for the cooler months. - Ensure your curtains and window are open to circulate fresh air into your home. - Monitor your loft for signs of pests, wasp nests are very common during this season. - If you have an open fire or wood burner, ensure your chimney is swept and prepared to be used during the winter months. Autumn External; - Clear your gutter during the end of autumn as trees will have dropped their leaves. - Insulate any outside pipes or taps ready for those frosty mornings. - Inspect your drains and be clear of any issues. Internal; - Check draught proofing around doors and windows. - Check that you have the correct about of insulation in your loft- aim for a minimum depth of 270mm. Winter External; - Check for any cracks in exterior walls that could be made worse by ice. - Check for any storm damage i.e. trees and fences, ensure these are not damaging your property. - Check your roof tiles after any high winds, they may have come loose or even fallen off. Internal; - Wipe away any signs of condensation, as this could lead to damp and rot. - Use extractor fans or leave windows on the latch to prevent moisture building up in your bathroom or kitchen. - Check your pipes regularly after a cold snap. These checks and fixes will keep your home in the condition that it deserves, a little TLC goes a long way- give these tips a try!", "pred_label": "__label__POS", "pred_score_pos": 0.5150208473205566}
{"content": "TY - BOOK ID - 46843 TI - Historical and Multidisciplinary Perspectives on Hope AU - van den Heuvel, Steven C. PY - 2020 SN - 9783030464899 DB - DOAB KW - Positive Psychology KW - Moral Philosophy KW - Sociology of Religion KW - Christian Theology KW - Heterodox Economics KW - Moral Philosophy and Applied Ethics KW - Hope Theory KW - Hope Theory and Positive Psychology KW - Hope and Human Economic Behaviour KW - Cognitive Psychology KW - Philosophy and Theology of Hope KW - Hope Development in Western Countries KW - Hope Research KW - Hope and Health Studies KW - Open Access KW - Positive psychology KW - Ethics & moral philosophy KW - Religion & beliefs KW - Sociology & anthropology KW - Christianity KW - Theology KW - Economic theory & philosophy UR - https://www.doabooks.org/doab?func=search&query=rid:46843 AB - This open access volume makes an important contribution to the ongoing research on hope theory by combining insights from both its long history and its increasing multi-disciplinarity. In the first part, it recognizes the importance of the centuries-old reflection on hope by offering historical perspectives and tracing it back to ancient Greek philosophy. At the same time, it provides novel perspectives on often-overlooked historical theories and developments and challenges established views. The second part of the volume documents the state of the art of current research in hope across eight disciplines, which are philosophy, theology, psychology, economy, sociology, health studies, ecology, and development studies. Taken together, this volume provides an integrated view on hope as a multi-faced phenomenon. It contributes to the further understanding of hope as an essential human capacity, with the possibility of transforming our human societies. ER -", "pred_label": "__label__POS", "pred_score_pos": 0.9159595966339111}
{"content": "OUR APPROACH\nOne Size Does Not Fit All.\nWe approach inclusion and diversity management through a multidisciplinary lens that includes research and methods from sociology, psychology, neuroscience, political science, organizational behavior, education, economics, and other disciplines.\nBy embedding inclusion into processes, policies, and culture, we help build a workspace that leverages human differences, works to increase organizational efficiencies and effectiveness and ensures employees feel valued, respected, and connected to your organization and its business objectives. DIAGNOSTIC & BENCHMARKING\nThe journey starts with diagnostic and benchmark assessments designed to identify unique strengths and opportunities. We use quantitative data to pinpoint where barriers exist, conduct qualitative research to understand why they exist, and then create a tailored strategy to nurture a culture of inclusion that promotes and sustains diversity and equity\nREFRAME BIAS\nUnconscious bias is a significant barrier not only to diversity and inclusion, but to effective decision-making, team collaboration, and management. Our customized program facilitates awareness and fosters an organizational culture that assumes and accepts bias is inherent in human decision-making. We create effective team-based practices to identify biases as they emerge, and counteract them on the fly, thus mitigating their impact.\nCULTURE OF INCLUSION\nTrue inclusivity demands an ongoing focus on the intrinsic value of a human-centric workplace and an action plan for creating a culture of belonging. Shaped by the feedback and data we retrieve during diagnostics, our inclusion prescription will provide specific strategies employees can use to cultivate a sense of belonging and equip managers and leaders with the knowledge and skills to build inclusive high-performing teams.", "pred_label": "__label__POS", "pred_score_pos": 0.8308296799659729}
{"content": "High-resolution IMS-MS under low-field conditions in a pressure- and temperature-controlled IMS drift cell allows separation of multiple protein conformers.\nOver the last decade, numerous papers have reported IMS-MS investigations of biomolecules, especially proteins. In these studies, IMS-MS is used to probe the three-dimensional shape of biomolecules as well as the composition, stoichiometry, and arrangement of units in biomolecular complexes. Yet, the majority of these studies were conducted either on drift-tube IMS instruments that do not operate under low-field conditions or on travelling wave IMS (TWAVE or TWIMS) instruments. Use of such instruments can lead to artifacts due to collisionally-induced heating and imprecise measurements of collision cross sections.\nThe TOFWERK IMS-TOF is a drift-tube based IMS-MS instrument that operates under low-field conditions with a high pressure- and temperature-controlled IMS cell. This ensures that native conditions are preserved during the ion mobility separation. Additionally, the IMS-TOF exhibits superior ion mobility resolution, thus allowing deeper insight into the conformational diversity of biomolecules. This is demonstrated here for the calcium-binding protein calmodulin, an essential and ubiquitous messenger protein. Calmodulin is activated by binding Ca\n2+ ions which substantially changes the structure of the protein and therefore its interactions within signalling pathways.\nAnalysis with the IMS-TOF reveals the conformational complexity of calmodulin. The data below were obtained either under denaturating conditions (apo; “no Calcium”) or under native ESI conditions (halo; “Calcium-bound”). Nitrogen was used as the buffer gas and the drift-tube was operated at 1000 mbar, 30°C and a reduced field- strength of 2 Td.", "pred_label": "__label__POS", "pred_score_pos": 0.9674126505851746}
{"content": "Extreme climate events such as droughts and heat waves exert strong impacts on ecosystems and human well-being. Estimations of the risks of climate extremes typically focus on one variable in isolation. In this study, we present a method to examine the likelihood of concurrent extreme temperature and precipitation modes at the interannual scale, including compound cool/dry and cool/wet events during the cold season as well as compound hot/dry and hot/wet events during the warm season.", "pred_label": "__label__POS", "pred_score_pos": 0.9920093417167664}
{"content": "How To Handle Coronavirus As A Small Business Owner thenshow symptoms, which poses a few problems. Despite what you hear on the news, you don't need to clean out the grocery store of their toilet paper, water, and canned goods and prepare for the end of times. However, you do need to take a couple precautions like washing your hands, covering your coughs and staying out of crowded spaces.\nAs a business owner, you're in a unique situation as you're not only responsible for your own safety around the virus, but your employees as well. Here are a few things to consider when thinking about what to do.\nDecide if you are keeping your doors open Have enough resources to support a remote-centric environment Make sure all cleaning supplies are stocked up Have a business continuity plan in place", "pred_label": "__label__POS", "pred_score_pos": 0.7919389009475708}
{"content": "ABOUT\nBrad Upham is an Assistant Professor in the Department of Pediatrics and Human Development. His research program focuses on how carcinogens alter cell signaling.\nDr. Upham received his Ph.D. from Virginia Polytechnic Institute & State University. He completed his postdoctoral training at the USDA and Louisiana State University. Additionally, he holds two Master’s degrees – one in Botany and the other in Environmental Toxicology and Engineering. He joined MSU as an Assistant Professor and leads the Research Translation Core at the MSU Superfund Research Program Center (MSU-SRP). This center focuses on the toxicology of dioxin and similar compounds identified as environmental contaminants in Michigan’s Tri-Cities.\nRESEARCH\nDr. Upham’s research investigates how environmental contaminants alter cell signaling pathways at the molecular level to produce adverse health outcomes, with particular emphasis on carcinogens. He also studies how natural products interact with these cell signaling pathways to prevent the toxic effects of environmental contaminants.", "pred_label": "__label__POS", "pred_score_pos": 0.5168859362602234}
{"content": "The Department of Education (DOE) has provided clarity on the reporting requirements for foreign gifts to and contracts with American universities after stepping up its scrutiny of such funding. DOE’s increased concern with foreign funding for universities has led to the arrest of a Harvard professor, who is charged with concealing payments he received from the Chinese government for research.\nSection 117 of the Higher Education Act requires that institutions report to the federal government any gift or contract with a foreign source valued at $250,000 or more “considered alone or in combination with all other gifts from or contracts with that foreign source within a calendar year.” In December, DOE issued a statement reminding universities of their obligations under the Act and announcing a new reporting system. DOE also requested a budgetary review of its new system from the Office of Management and Budget (OMB) and called for public comment.\nAfter receiving 41 comments, DOE responded with explanations about several issues on which higher education associations had previously sought clarification. For example, it confirmed that there is a rebuttable presumption that foreign gifts and contracts received through legal entities, such as foundations that operate substantially for the benefit for or under the auspices of a university, must be disclosed. DOE further explained that universities must disclose the name and address of the specific foreign source and unredacted copies of any contract with a foreign source, but it will not make this information publicly available. For donors who wish to remain anonymous, DOE explained that “their names and addresses must be shared with the Department to the extent that the institution has or could reasonably obtain the donor’s identity” but such information will also not become public.\nWhile contracts that involve payment from a foreign source to an institution are reportable, contracts that involve the transfer of funds from an institution to a foreign source are not reportable, according to DOE. Additionally, reportable contracts include intellectual property license fees from a foreign source of a university patent. DOE also noted that if a foreign source pays tuition for students and the payment meets the $250,000 threshold, such payment is considered a “contract” and is reportable.\nDOE previously sent letters to several American universities requesting information about gifts from and contracts with foreign sources such as China, Qatar, and Russia. Foreign funding for U.S. universities has come under increasing scrutiny amid concerns of foreign influence in the U.S., including reports of Russian meddling in U.S. elections and censorship by the Chinese government. The Department of Justice (DOJ) has also addressed foreign influence in the U.S. through aggressive enforcement of the Foreign Agents Registration Act (FARA).\nImage by Harvard University", "pred_label": "__label__POS", "pred_score_pos": 0.9977204203605652}
{"content": "Research output: Contribution to journal › Article\nJames DeGregori, Paul Pharoah, Peter Sasieni, Charles Swanton\nScreening leads to meaningful reductions in deaths from cancers. However, reductions in all-cause mortality (ACM) are harder to demonstrate. Failure to demonstrate ACM benefit should not diminish advances in cancer screening. We consider how co-morbidities related to an aging and damaged soma can hinder achievement of ACM benefit.", "pred_label": "__label__POS", "pred_score_pos": 0.9986428022384644}
{"content": "Link to Pubmed [PMID] – 33022088 Link to DOI [DOI] – 10.1111/1462-2920.15271\nEnviron Microbiol 2020 Oct; ():\nDeep-sea hydrothermal vents are inhabited by complex communities of microbes and their viruses. Despite the importance of viruses in controlling the diversity, adaptation and evolution of their microbial hosts, to date, only eight bacterial and two archaeal viruses isolated from abyssal ecosystems have been described. Thus, our efforts focused on gaining new insights into viruses associated with deep-sea autotrophic archaea. Here, we provide the first evidence of an infection of a hyperthermophilic methanogenic archaea by a head-tailed virus, Methanocaldococcus fervens tailed virus 1 (MFTV1). MFTV1 has an isometric head of 50 nm in diameter and a 150 nm-long non-contractile tail. Virions are released continuously without causing a sudden drop in host growth. MFTV1 infects Methanocaldococcus species and is the first hyperthermophilic head-tailed virus described thus far. The viral genome is a double-stranded linear DNA of 31 kb. Interestingly, our results suggest potential strategies adopted by the plasmid pMEFER01, carried by M. fervens, to spread horizontally in hyperthermophilic methanogens. The data presented here opens a new window of understanding on how the abyssal mobilome interacts with hyperthermophilic marine archaea. This article is protected by copyright. All rights reserved.https://pubmed.ncbi.nlm.nih.gov/33022088", "pred_label": "__label__POS", "pred_score_pos": 0.562932014465332}
{"content": "Languages are a key part of our European identity and culture. Linguistic diversity is supported and celebrated as part of the EU’s motto “United in Diversity”. However, the EU alone has 24 official languages, which can lead to language barriers, hampering the free flow of ideas, information, commerce and culture. The German EU Council Presidency Translator will address this challenge during the upcoming German EU Council Presidency.\nThe free online machine translation service can be used to translate websites, documents or text directly entered on the translator page from and into all EU languages, allowing EU citizens to communicate across languages and borders.\nThe Translator is developed using German and European high-tech AI. It uses systems from leading Centers of Excellence and companies like the German Research Center for Artificial Intelligence (DFKI), DeepL and\nTilde as well as with eTranslation, the European Commission's machine translation system. It is funded by the Federal Foreign Office.\nThe German EU Council Presidency Translator was released on July 1st, 2020 and will remain available online for the whole duration of the German EU Council Presidency. For further information, please visit presidencymt.eu/page/about. If you have any questions about the German EU Council Presidency Translator or if you require technical assistance, please contact info@presidencymt.eu.\nLink to translation service: https://www.presidencymt.eu Link to the website of the German Presidency of the Council of the European Union: https://www.eu2020.de/eu2020-en", "pred_label": "__label__POS", "pred_score_pos": 0.8208023309707642}
{"content": "The International Finance Corporation – IFC, a member of the World Bank Group, has announced an investment up to $100 million in Nigeria’s Zenith Bank Plc. To help it increase support to clients and companies whose cash flows have been disrupted by challenges caused by the COVID-19 pandemic.\nIFC’s loan to Zenith Bank is its first investment in Africa through its COVID-19 fast-track financing support package. The funding will help Zenith, an existing IFC client, overcome challenges resulting from ongoing, limited access to foreign currency, working capital, and trade funding.\nZenith will support dozens of businesses in Nigeria’s health, pharmaceuticals, food, and trading sectors, allowing them to strengthen operations, maintain employment, and critical access imports of goods, commodities, and raw materials during these challenging economic times.\nEbenezer Onyeagwu, Group Managing Director/CEO of Zenith Bank, said, “IFC’s support is essential and will help us respond to challenges resulting from the COVID-19 pandemic. It will allow us to support compelling export initiatives and trade financing for critical goods and materials, especially for the medical and pharmaceuticals sectors. Our partnership with IFC is strong, and we are committed to its environmental, social, and governance (ESG) requirements.”\nThe closure of borders, shutting of businesses, and reduced global trade-related to COVID-19 are affecting Nigeria’s economy and others across Africa, with the World Bank predicting Africa’s first recession in 25 years.\nIFC’s loan to Zenith is part of its $8 billion global fast-track financing package, announced in March to support business activity and preserve jobs in the face of COVID-19. Close to 300 clients have requested support globally.\nEme Essien Lore, IFC Country Manager in Nigeria, said, “IFC’s support for Nigeria’s banking sector will help keep the wheels of Nigeria’s economy turning at a time when it is facing a major challenge from COVID-19. Our experience from past shocks, including the global financial crisis in 2008, has taught us that keeping companies solvent is key to saving jobs and limiting economic damage.”\nZenith has more than 400 branches in Nigeria and serves over 9 million corporate and individual clients within its global footprint. IFC’s overall portfolio in Nigeria stands at $1.3 billion, in sectors including manufacturing, financial services, infrastructure, and technology.", "pred_label": "__label__POS", "pred_score_pos": 0.940993070602417}
{"content": "Abstract reb genes code for R-bodies: large, extendable polymers that are known for their roles in obligate endosymbioses. In the non-endosymbiotic pathogen Pseudomonas aeruginosa, reb homologues are part of a cluster found in virulent strains. Here, we demonstrate that R-bodies are produced in abundance by P. aeruginosa PA14 subpopulations during biofilm growth, identify regulators of reb gene expression, and show that reb genes are required for full colonization and virulence in host models. Competing Interest Statement\nThe authors have declared no competing interest.", "pred_label": "__label__POS", "pred_score_pos": 0.6644140481948853}
{"content": "Thyroid over-replacement may increase atrial fibrillation, stroke risks\nCHICAGO— Among a large cohort of adults prescribed thyroid hormone replacement therapy, those with low thyroid-stimulating hormone levels had more atrial fibrillation and strokes, according to study data presented at the American Thyroid Association annual meeting.\nMaria Papaleontiou\n“Our study provides new insights on the risks of atrial fibrillation and stroke in patients being treated with exogenous thyroid hormone,”\nMaria Papaleontiou, MD, assistant professor of internal medicine in the division of metabolism, endocrinology and diabetes at the University of Michigan, told Endocrine Today. “We found that despite controlling for known cardiovascular risk factors, such as smoking, hypertension, etc, low serum TSH was associated with both incident atrial fibrillation and stroke.”\nPapaleontiou and colleagues analyzed data from the Corporate Data Warehouse of the Veterans Health Administration collected between 2004 and 2017 on 756,555 adults who were prescribed thyroxine alone or T\n4 plus liothyronine. Patients with thyroid cancer and those with medications that alter thyroid function tests, such as amiodarone, were excluded\nAll patients had at least two available TSH measurements, and 29% of them had at least one measurement less than 0.5 mIU/L, indicating over-replacement, according to Papaleontiou. Among the entire cohort, 10.5% had atrial fibrillation and 2.4% experienced a stroke.\nUsing multivariable generalized linear mixed-effects models, the researchers found that incident atrial fibrillation was statistically significantly associated with lower vs. higher TSH level (OR = 0.97; 95% CI, 0.96-0.97), older vs. younger age (e.g. age ≥85 years: OR = 9.46; 95% CI, 8.98-9.96 compared to age 18-49) and cardiovascular risk factors such as hypertension (OR = 1.73; 95% CI, 1.69-1.78). Similarly, stroke was significantly associated with lower TSH (OR = 0.98; 95% CI, 0.97-0.99) even when adjusting for other cardiovascular risk factors including history of prior atrial fibrillation.\n“Low TSH was independently associated with incident stroke in thyroid hormone users, even when controlling for prior history of atrial fibrillation, the most common mechanism thought to lead to stroke in hyperthyroidism,” Papaleontiou said. “This suggests that there may be additional mechanisms leading to increased risk of stroke in patients who are over-replaced with thyroid hormone.” –\nby Jill Rollet Reference:\nPapaleontiou, M. Oral Abstract 12. Presented at: 89th Annual Meeting of the American Thyroid Association; Oct. 30-Nov. 3, 2019; Chicago.\nDisclosure: Papaleontiou reports no relevant financial disclosures.", "pred_label": "__label__POS", "pred_score_pos": 0.6075583100318909}
{"content": "Advice for dating an older man\nThey explain that a change in mindset is essential for women over 60 who want to find romance.In my recent interview with dating coach, David Wygant, he suggested that men are often the ones who lack confidence and suffer from fear of rejection.A healthy sex life can include giving pleasure in many ways: using words, kissing, erotic touch, oral sex, even sex toys.\nThese days, women expect to get as much pleasure as men do from sex and the older man might need a while to adjust to that idea.\nIn fact, older men and women are often more comfortable with their bodies and more knowledgeable about what a partner might enjoy. ED is often caused by clogging or tightening of the blood vessels leading to the penis, which in turn leads to poor functioning of the erectile tissue. As many as half of American men aged 40 to 70 have had some degree of erectile difficulty. These men cannot get or maintain an erection at all.\nAnd the confidence that comes with aging can be very sexy. The likelihood of developing ED increases with age. Certain medications, including some blood pressure medicines, can also contribute to ED.\nHe says that older women have the power to make a connection that turns into a dating opportunity.\nFor example, three simple ideas for creating dating opportunities include smiling genuinely, approaching men first and learning the art of flirting.\nWell, many women would argue that the same comment applies to dating after 60.", "pred_label": "__label__POS", "pred_score_pos": 0.6626125574111938}
{"content": "In this session, you’ll hear about topics such as how Americans plan for financial security and retirement and whether they feel it needs improvement, where young professionals are on the road to financial security and if they’re moving in the right direction, attitudes toward student loan debt, money and financial decision making, and how people prioritize where their money is spent, the financial state of individuals and the country as a whole, and how long people plan to work, whether this is by necessity or choice, and their preparedness to live long lives. The session will be interactive and engaging.\nIhssane is the President and Co-Founder of Connecticut Young Professionals. He formulates and implements the strategic plan that guides the direction of CTYP. With a tremendous commitment to the community, he connects groups and individuals to CTYP for mutual benefit.\nAs a Financial Adviser, Ihssane cultivates relationships with responsible and successful individuals and business owners who are seeking guidance on how to achieve current financial success and how to grow to protect and preserve their assets over the long term. Whether the focus is family or business, Ihssane works with individuals to identify financial goals, provide solutions to help them reach those goals, and how to implement these suggestions.", "pred_label": "__label__POS", "pred_score_pos": 0.5478716492652893}
{"content": "We are in the Garden of Gethsemane on the night Jesus is arrested. He has been praying, speaking with His Father about what is to come. That's something we should consider: Jesus has no sin to interfere with His relationship and His understanding of God's will. He knows.\nHe still takes time to pray. And do we?\nHis prayer is first for the current disciples. They are going to face difficulties and Jesus is well aware of those challenges. He knows that they will be persecuted and executed for obeying Him. And this is not \"you can't have a discount on your airline tickets\" inconvenience but true persecution: prisons, pain, death.\nA key component is John 17:19 where Jesus speaks of sanctification coming through truth. We tend to think in other terms, more subjective terms than \"truth.\" Or, these days, people speak of \"their truth\" as if truth is something that can shift from person to person. That's not truth. Truth is static, fixed--understandings can change, what people perceive to be truth can change--but truth does not shift. If Jesus is the truth (see John 14:6), then becoming like Christ is connected to seeking the unchangeable truth.\nThe pursuit of truth, then, is part of the Christian life. There is nothing inherently Christian about remaining in ignorance nor of neglecting the knowledge that God has made available. Neither is there a virtue to pursuing knowledge exclusive of the Creator---if Jesus is the truth then ultimate understanding must, by nature, include Him.\nThis is why our worship-filled lives as Christians must involve a great deal of wonder at so much. The specific, special revelation that is the Word of God must not be neglected and indeed must reach first place. But the remainder of the general revelation in Creation must be studied, the amazing things at human creativity can achieve, all belong within the bounds of what we study and appreciate.\nFrom there, Jesus goes on to pray for all those who will believe from the preaching of the disciples. I would recommend that you pick up from this that Jesus knew there would be a length of time between His ascension and return. And that the disciples should have known that as well--be careful with the view that suggests the disciples expected an immediate return. It is likely that they did, at times, become frustrated that Jesus did not come back as soon as they wanted. My word--that hits many a preacher when the Lord does not return on Saturday night! However, I don't think we give the disciples enough credit for the Holy Spirit working in them after the Resurrection.\nStill, we are in the line of those who believed because of the preaching of the disciples. That puts us in those Jesus prays for. Perhaps, then, we should examine what He prayed for and see what it would look like to obey His words. He prays for unity and love--these are not mystical moments that will just happen. We can choose to obey, choose to seek unity in His truth. Or we can not.\nThen comes my favorite part of this reading: the arrest of Jesus. Why? Look at John 18:5-6. The arresting posse shows up to take Jesus, He asks who they seek--and they say \"Jesus of Nazareth.\" His answer is two words in Greek:\n\"I am.\"\nSeriously. That's His answer. The same name that God revealed to Moses in Exodus 3. Jesus demonstrates His unity with God with this. And then take a look at what happens to the crowd:\nThey fall down. Some interpreters take this to mean they deliberately fell at His \"blasphemy.\" I take it the other way: at the Word of Jesus, they are struck down. They cannot stand in His presence. It's not their choice. It is His power.\nAnd Peter thinks that his sword will help...\nWe do the same thing. Our swords, our scheming, our plans--all of these are useless compared to the Word of God. There comes a time to lay down our titles, our labels, our methods, and our personal views aside for the sake of the Word of God.", "pred_label": "__label__POS", "pred_score_pos": 0.7983789443969727}
{"content": "Growth Trends for Related Jobs\nA real estate transaction coordinator functions as a liaison between real estate agents, clients, escrow companies and mortgage brokers during the process of a real estate sale. Many real estate brokerages hire transaction coordinators to effectively manage the administrative tasks involved in closing a sale, according to Clareity Consulting.\nEducation and Job Prerequisites\nReal estate transaction coordinators can be either licensed or unlicensed real estate agents. Benefits of having a real estate license include a potential for increased pay and the ability to communicate more effectively with agents and clients. Unlicensed real estate transaction coordinators cannot negotiate or disclose pricing terms to clients. Regardless of licensing, a real estate transaction coordinator needs a solid clerical or administrative background and some knowledge of real estate as a job prerequisite. Formal training is not necessarily required, nor is any specific college degree.\nEscrow Duties\nA real estate transaction coordinator receives a ratified purchase contract from an agent, opens the escrow and supplies the escrow or title officer with the necessary information to begin the process of managing the file. The real estate transaction coordinator arranges for pickup of the initial deposit money. Additionally, the real estate transaction coordinator sends the cooperating agent any necessary disclosures required by law.\nTime Frames and Deadlines\nTransaction coordinators are in charge of creating timelines for important dates such as deadlines for loan and inspection contingency removals. A few days before a deadline, the real estate transaction coordinator calls or emails a reminder to the real estate agent, so that all responsibilities are met. Sometimes a real estate transaction coordinator orders a natural hazard disclosure statement on behalf of the seller or schedules a home inspection for a buyer.\nAdministrative Tasks\nAdministrative work is a big part of the real estate transaction coordinator's work. Duties include maintaining the file to ensure all the mandatory disclosures are completed and sent to the cooperating agent or broker for the client’s review and approval. As each document returns by mail, fax or email, the real estate transaction coordinator checks for all initials, signatures and dates before marking the disclosures as complete and filing them. Additionally, a real estate transaction coordinator calls the agents and other parties to remind them of missing documents.\nQuality Control\nTransaction coordinators ensure the smooth and efficient management of the steps necessary to close a sale. A client or agent often relies on a real estate transaction coordinator to monitor and assess the progress of the sale so that important deadlines are met and contingencies are released. Furthermore, a real estate transaction coordinator provides a preliminary audit of the file for the managing broker to review.\nAdditional Duties\nSome real estate transaction coordinators produce marketing for agents, such as ''Just Sold'' postcards or monthly newsletters. Other real estate transaction coordinators are licensed agents who can assist the agent with renegotiating terms after a pest inspection reveals wood rot damage that needs to be fixed before a loan funds.\nReferences\nWriter Bio\nAngela Lam Turpin has been a writer for 20 years. Her articles and essays have appeared in \"San Jose Mercury News,\" \"The Sun,\" and in the book, \"Wild Child: Girlhoods in the Counterculture\" (Seal Press). She is a licensed Realtor (CA Dept of Real Estate License #01201734) experienced with residential sales, mortgage loans, and foreclosures.\nPhoto Credits\nmichaeljung/iStock/Getty Images", "pred_label": "__label__POS", "pred_score_pos": 0.6616589426994324}
{"content": "Abstract\nObjective: To evaluate the effectiveness of olanzapine versus aripiprazole in patients with schizophrenia. Method: Patients aged 18 to 65 years with schizophrenia (diagnosed according to DSM-IV-TR criteria) were randomly assigned to either olanzapine (n = 281) or aripiprazole (n = 285) for 28 weeks of double-blind treatment. The primary outcome was time to all-cause discontinuation. Efficacy was measured by Positive and Negative Syndrome Scale (PANSS) total change from baseline. Time-to-event data were analyzed via the Kaplan-Meier method. The study was conducted from October 2003 to July 2007. Results: Treatment groups did not differ significantly in time to all-cause discontinuation (p = .067) or all-cause discontinuation rate (olanzapine, 42.7% vs. aripiprazole, 50.2%; p = .053). Olanzapine-treated patients had significantly longer time to efficacy-related discontinuation (p < .001) and a significantly lower efficacy-related discontinuation rate (olanzapine, 8.9% vs. aripiprazole, 16.8%; p = .006). Olanzapine-treated patients had a significantly greater mean decrease (last observation carried forward) in PANSS total score (-30.2) than did aripiprazole-treated patients (-25.9, p = .014). Olanzapine-treated patients had a mean weight change of +3.4 kg (vs. +0.3 kg for aripiprazole-treated patients; p < .001) and a significantly greater incidence of ≥ 7% body weight gain at any time (40.3% vs. 16.4%; p < .001). Fasting mean glucose change was +4.87 mg/dL for olanzapine and +0.90 mg/dL for aripiprazole (p = .045). Incidence of baseline glucose < 100 mg/dL and ≥ 126 mg/dL at any time was 1.7% for olanzapine and 0.6% for aripiprazole (p = .623). Fasting mean total cholesterol change was +4.09 mg/dL for olanzapine and -9.85 mg/dL for aripiprazole (p < .001). Incidence of baseline total cholesterol < 200 mg/dL and ≥ 240 mg/dL at any time was 9.2% for olanzapine and 1.5% for aripiprazole (p = .008). Fasting mean triglycerides change was +25.66 mg/dL for olanzapine and -17.52 mg/dL for aripiprazole (p < .001). Treatment groups did not significantly differ on measures of extrapyramidal symptoms. Conclusion: Treatment groups did not differ significantly on the primary outcome. Olanzapine-treated patients had significantly greater improvement in symptom efficacy at 28 weeks as well as significantly greater mean increases in weight and glucose and significantly greater worsening on lipids parameters. Trial Registration: clinicaltrials.gov Identifier: NCT00088049.\nASJC Scopus subject areas Psychiatry and Mental health", "pred_label": "__label__POS", "pred_score_pos": 0.5495592355728149}
{"content": "Monday, October 7, 2019\nThe GAO recently released a new report, Social Security Benefits: SSA Needs to Improve Oversight of Organizations that Manage Money for Vulnerable Beneficiaries. Here are the highlights:\nWhat GAO Found\nThe Social Security Administration (SSA) approves organizational payees—such as nursing homes or non-profits that manage the Social Security benefits of individuals unable to do so on their own—by assessing a range of suitability factors, such as whether the organizations have adequate staff to manage benefits for multiple individuals. However, GAO found that SSA's policy does not specify how to assess more complex suitability factors, such as whether an organization demonstrates sound financial management. Without clearer guidance, unqualified or ill-prepared organizational payees could be approved to manage benefits. Also, SSA does not currently require background checks for key employees of an organizational payee. In contrast, SSA requires background checks for individual payees—such as a relative or friend of the beneficiary. A comprehensive evaluation could help SSA determine whether and how to expand their use of background checks to organizational payees.\nTo ensure organizational payees are managing funds appropriately, SSA uses several monitoring tools, including resource-intensive onsite reviews. Certain organizational payees, such as those that charge fees for their services or have 50 or more beneficiaries (high-volume), receive onsite reviews every 3 to 4-years. In contrast, payees that serve fewer than 50 beneficiaries (low-volume)—the vast majority—are selected for review based on their estimated likelihood of misusing beneficiary funds, and a relatively low percent of them receive onsite reviews (see figure). SSA uses a predictive statistical model to identify higher risk low-volume payees, but the model's effectiveness cannot be fully assessed by GAO or others due to missing documentation on how it was designed. SSA officials said they will update the model in the future, but do not have a time frame for doing so. Establishing such a time frame and documenting design decisions are key steps toward assessing the model's effectiveness.\n. . .\nWhat GAO Recommends\nGAO is making nine recommendations in this report, including that SSA: clarify how to assess complex suitability factors; assess requiring background checks for organizational payees; establish a timeframe for reviewing the predictive model and document design decisions resulting from that review; and establish timeframes for, and conduct revisions of the accounting form. SSA agreed with all nine recommendations and provided technical comments that GAO incorporated as appropriate.\nThe full report is available here.\nhttps://lawprofessors.typepad.com/elder_law/2019/10/new-report-ssa-needs-more-oversight-of-those-who-handle-vulnerable-beneficiaries-.html", "pred_label": "__label__POS", "pred_score_pos": 0.8900831937789917}
{"content": "This study , published by the American College of Medical Genetics and Genomics, analyses clinical data for 87 patients with a molecularly confirmed diagnosis of MWS, including 62 previously reported patients and 25 unpublished cases, and compared them with patients previously reported by other authors. The data was obtained through collaborations involving clinicians from various countries. Such primary data have never been collated from a large cohort of affected individuals. In this article we present a comprehensive study of MWS features underlining a highly consistent phenotype for the disease, its genotype–phenotype correlations, and the phenotypic and clinical evolution taking place with age. The purpose of the article is to assist clinicians to identify the disease and to provide them with updated care recommendations for patient management.", "pred_label": "__label__POS", "pred_score_pos": 0.5722591876983643}
{"content": "The Florida Public Service Commission (PSC) recently approved a renewable natural gas (RNG) program for Peoples Gas System, marking the first time a Florida natural gas utility will offer biogas producers the option of delivering RNG into its distribution system.\nAs the PSC explains, RNG – biogas that has been processed to meet pipeline quality standards – is produced from materials such as wastewater treatment plants, landfills, municipal solid waste, livestock manure, and agricultural waste. Peoples Gas has been approached by landfill operators and wastewater treatment plant owners who want to deliver RNG into the utility’s distribution system.\nAccording to the PSC, the biogas producer could use the RNG onsite or contract with a customer who will purchase the RNG from the biogas producer. Potential customers may include compressed natural gas (CNG) refueling stations and industrial customers, or Peoples could purchase the RNG, thus displacing a portion of traditional (geologic) natural gas with RNG.\nPotential RNG projects include waste-to-energy requests for proposals issued by local governments, including Hillsborough, Polk, and Volusia Counties, and the City of St. Petersburg to reuse gas that now escapes into the atmosphere or is flared (burned off).\n“We are excited to be the first utility in Florida – and among the first in the country – to offer this innovative new service,” says T.J. Szelistowski, president of Peoples Gas, in a press release. “This is a win for the environment, a win for our customers, and a win for the communities we serve.”\nThe PSC unanimously approved the new utility service, which will offer the opportunity for Peoples Gas to clean, condition and transport a customer’s biogas. According to the utility, the new conditioning service is expected to be available to customers in 2018.", "pred_label": "__label__POS", "pred_score_pos": 0.5378631353378296}
{"content": "Providing monetary and non-monetary goods to research participants in Zambia\nFactors considered when offering monetary goods\n- compensation for time, transport, parking etc.\n- required by Research Ethics Committee\n- difficulty in recruiting\n- wage rate\nFactors considered when offering non-monetary goods\n- advised by the community\n- used previously by self or colleague\n- required by Research Ethics Committee\n- reward participants for their time\n- food offered as lunch\n- non-monetary goods deemed more appropriate\n- difficulty in recruiting\nAll participating Research Ethics Committees confirmed that they review health research involving human participants and most of them were unable to provide the policy for review.\n# Global Bioethics", "pred_label": "__label__POS", "pred_score_pos": 0.9993661046028137}
{"content": "►▼Show Figures\nHydrogel-based bio-inks have recently attracted more attention for 3D printing applications in tissue engineering due to their remarkable intrinsic properties, such as a cell supporting environment. However, their usually weak mechanical properties lead to poor printability and low stability of the obtained structures. To obtain good shape fidelity, current approaches based on extrusion printing use high viscosity solutions, which can compromise cell viability. This paper presents a novel bio-printing methodology based on a dual-syringe system with a static mixing tool that allows in situ crosslinking of a two-component hydrogel-based ink in the presence of living cells. The reactive hydrogel system consists of carboxymethyl chitosan (CMCh) and partially oxidized hyaluronic acid (HAox) that undergo fast self-covalent crosslinking via Schiff base formation. This new approach allows us to use low viscosity solutions since in situ gelation provides the appropriate structural integrity to maintain the printed shape. The proposed bio-ink formulation was optimized to match crosslinking kinetics with the printing process and multi-layered 3D bio-printed scaffolds were successfully obtained. Printed scaffolds showed moderate swelling, good biocompatibility with embedded cells, and were mechanically stable after 14 days of the cell culture. We envision that this straightforward, powerful, and generalizable printing approach can be used for a wide range of materials, growth factors, or cell types, to be employed for soft tissue regeneration.View Full-Text\nThis is an open access article distributed under the Creative Commons Attribution License\nwhich permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited", "pred_label": "__label__POS", "pred_score_pos": 0.7574319243431091}
{"content": "Focal muscular atrophy (FMA) has various causes and, hence, various signs and symptoms.\nMuscle wasting is probably the presenting symptom when the onset is insidious (see images below). Weakness may not be a primary symptom in these patients.A man with neuralgic amyotrophy presenting with wasting of deltoids involving the right side more than the left.A middle-aged man with (atypical) anterior horn cell disease presenting with wasting of the right quadriceps.\nMuscle weakness occurs when the onset is more abrupt.\nDistal weakness in the upper limbs may manifest with the following difficulties: opening jars, holding tightly to a pencil, typing, fingering a musical instrument, buttoning a shirt, or tying shoelaces.\nProximal weakness in upper limbs may manifest with difficulty in raising the arms or reaching for high objects.\nWeakness of lower limb muscles may result in the following difficulties: walking, climbing stairs, walking on uneven surfaces, and stumbling over small objects.\nMuscle twitching (fasciculations) occurs when anterior horn cells or proximal roots are involved.\nMuscle cramps, commonly experienced in the gastrocnemius muscles, are characterized by sudden, brief, intense muscle pain; a strong, hard, palpable muscular contraction; and immediate relief by stretching the muscle.\nSensory symptoms (eg, pain, numbness, tingling or burning sensation) suggest involvement of roots, plexi, or peripheral nerves.\nTrophic changes may be seen when small fibers of the peripheral nerve are involved or a defect in pain, temperature, or joint-position sensation is noted.\nSystemic symptoms suggest diabetes, arthritis, articular injury, collagenosis, malignancy, abuse of prescription or nonprescription drugs, or intravenous (IV) drug abuse.\nGeographic preponderances of monomelic amyotrophy, polio, and leprous neuropathy have been recognized. Consider such diseases in immigrants from the appropriate geographic regions.\nA history of affected family members may suggest genetic disorders such as spinal muscle atrophy (SMA) or a familial clustering due to infectious disease or environmental mechanisms.\nPast history of polio, trauma, radiation, electrical injury, malignancy, or lymphoma should suggest an etiology for FMA.\nOccupational exposure to toxins may lead to FMA.", "pred_label": "__label__POS", "pred_score_pos": 0.5065593719482422}
{"content": "8 (sorry, 10) Habits of Highly Effective Google Managers.\nAre managers really necessary? Google wanted to know for sure, so in 2002, it experimented by removing bosses from its hierarchy.\nThe answer was a resounding yes. Managers were critical not only for structure and clarity, but also for team performance.\nAfter Google discovered that its teams needed great managers, it wanted to know the characteristics that made some bosses more effective than others.\nIn 2008, Project Oxygen (an initiative to uncover the traits of Google's best managers)gathered 10,000 manager observations including performance reviews, surveys, and nominations for top-manager awards and recognition. After analyzing the data, Google stumbled upon a realization that surprised many--even its former senior vice president of people operations, Laszlo Bock.\nIn a New York Times article that revealed the findings, Bock acknowledged that the company had historically hired managers or promoted people who exhibited a higher level of technical expertise than others.\n\"It turns out that that's absolutely the least important thing,\" Bock says. \"It's important but pales in comparison. Much more important is just making that connection and being accessible.\"\nBock's team of people experts didn't stop there.\nUpon further analysis of the findings, they narrowed in on \"Eight Habits of Highly Effective Google Managers.\" Be a good coach. Empower your team and don't micromanage. Express interest in an employee's success and well-being. Be productive and results-oriented. Be a good communicator and listen to your team. Help your employees with career development. Have a clear vision and strategy for the team. Have key technical skills, so you can help advise the team.\nHowever, 2008 was a long time ago. Since, Google has increased in size and complexity, and so has the demands on its managers. To ensure the Eight Habits were still relevant, Google gathered additional employee feedback and revisited the research. Two major themes arose. Googlers wanted to see:\nmore effective cross-organization collaboration and\nstronger decision-making practices from leaders.\nWhat Google discovered was that the traits of its effective bosses had evolved with the company. As a result, it updated habits Nos. 3 and 6 from above and added two more. I've provided my personal thoughts on the significance of each.\nNo. 3 (updated). Creates an inclusive team environment, showing concern for success and well-being.\nCreating an environment in which everyone feels included and a sense of belonging is the first step toward showing genuine concern for employees' well-being. An inclusive team environment ensures that everyone's voice is heard and that all team members feel like they can bring their full selves with them to work.\nIt doesn't matter how much you care if, at the end of the day, employees don't feel part of the team. Instead, create an environment that universally empathizes with and celebrates everyone's differences.\nNo. 6 (updated). Supports career development and discusses performance\nThe two go hand-in-hand. Development opportunities that are not driven by performance feedback are a poor use of time and resources.\nWhen managers provide feedback and then follow it up with a customized development plan, employees walk away from performance reviews feeling encouraged and supported rather than frustrated and confused.\nIt's a responsibility of managers to not only serve as a sounding board as individuals consider development opportunities, but also to ensure their efforts lead to improved performance.\nNo. 9 (new). Collaborates across Google\nIt's hard for teams to gain traction and earn support from others when their managers operate with a compartmentalized mentality. Now, more than ever, a team's effectiveness relies on its ability to collaborate with others and create comprehensive solutions.\nIt's critical that managers remove silos across the organization and create stronger, more deliberate connections between people, teams, functions, and locations.\nNo. 10 (new). Makes strong decisions\nNo one likes spinning their wheels or seeing work stalled due to ineffective decision making. It's important that managers provide guidance and act swiftly to ensure their team's work stays on track, and the impact is maximized.\nTo ensure informed decisions are made, Google encourages managers to test their ideas out loud and collect feedback by explicitly advocating for their opinions (voicing individual views, reasoning, and providing data), testing their understanding by inquiring about others' perspectives (soliciting ideas and feedback), and then synthesizing the responses to ensure a comprehensive understanding before making a decision.\nAs our respective markets change and our companies evolve, it's important that our people grow at the same rate as the business. Hats off to Google for revisiting old research and ensuring its managers change with the times.", "pred_label": "__label__POS", "pred_score_pos": 0.9538083076477051}
{"content": "Abstract\nPurpose of review Corneal astigmatism is a common refractive error observed in a significant percentage of cataract patients. Accurate measurements of the preexisting corneal astigmatism are essential in order to achieve the desired refractive outcome after toric intraocular lens (IOL) implantation. This article presents a comprehensive review of recent published literatures on methods for measuring preoperative corneal astigmatism for toric IOL implantation.\nRecent findings A variety of instruments has been introduced and used to measure the magnitude and meridian of corneal astigmatism during preoperative assessments of cataract patients. Instruments that consider both the anterior and posterior corneal surfaces as critical factors for measuring total corneal astigmatism are expected to provide better accuracy. Although these instruments facilitate improved evaluations of corneal astigmatism and have helped minimize postoperative residual astigmatism, a perfect method to analyze preoperative corneal astigmatism has not yet been established.\nSummary Perfect correction of astigmatism after toric IOL implantation by using accurate corneal astigmatism values is the goal of this surgical procedure. To achieve this, correct and precise measurements of corneal astigmatism to determine the magnitude and meridian should be obtained.\nAll Science Journal Classification (ASJC) codes Ophthalmology", "pred_label": "__label__POS", "pred_score_pos": 0.9164730906486511}
{"content": "Wednesday, August 28, 2019 DTI Remains Steadfast in Extending “Malasakit” to Marawi IDPs\nThe Department of Trade and Industry (DTI) together with other members of the Task Force Bangon Marawi (TFBM) Subcommittee on Business and Livelihood continue to foster livelihood growth for internally displaced persons (IDPs) affected by the Marawi siege through the Kawiyagan program.\nDubbed as “Siyap sa Marawi, Gagaw ko Pagtao” (Pag-aalaga sa Marawi, Pagmamahal sa Kapwa), Kawiyagan is a series of distribution of livelihood assistance to the IDPs affected by the Marawi siege. The program is one of the TFBM’s initiatives in refreshing Marawi City’s illustrious business environment. Last August 22 marked the first anniversary of the Kawiyagan program since its launching on August 24, 2018.\nDuring the program’s launching anniversary, DTI-10 Regional Director Linda Boniao emphasized its essence being an avenue not limited to the distribution of livelihood starter kits, but also a way to showcase the beneficiaries’ outputs, and how different agencies complement each other’s livelihood interventions.\nKawiyagan also ensures that livelihood programs will be immediately provided directly to the IDPs and it encourages other stakeholders to provide livelihood assistance to the IDPs. This ongoing initiative of the TFBM serves as an inspiration for the IDPs’ fellow residents of Marawi.\nThe Subcommittee on Business and Livelihood is chaired by DTI with member agencies the Department of Agriculture (DA), Department of Agrarian Reform (DAR), Department of Environment and Natural Resources (DENR), Department of Labor and Employment (DOLE), Department of Science and Technology (DOST), Technical Education and Skill Development Authority (TESDA), Cooperative Development Authority (CDA), local government units (LGUs) of Marawi City and Lanao del Sur and humanitarian organizations.\nAs of August 23, 2019, 17,680 beneficiaries or 36% of the target 49,000 IDPs by the end of 2019, have already received starter kits from the DTI-TFBM livelihood interventions. The Department has released more than P200M worth of the starter kits including sari-sari store, bigasan, sewing, school supplies, carinderia, carpentry, electronic tools, and e-loading.\nTFBM, through its Subcommittee on Business and Livelihood led by DTI, ensures the unceasing assistance for the revival of businesses and livelihood projects in the affected city.", "pred_label": "__label__POS", "pred_score_pos": 0.751995325088501}
{"content": "Protocols for Encounter with Extraterrestrials: Lessons from the Covid-19 Pandemic J. W. Traphagan et al. (2020), JBIS, 73, pp.234-238 Refcode\n: 2020.73.234\nKeywords\n: SETI, Covid-19, Pandemic, Risk, Cultural diversity\nAbstract:\nThis paper explores lessons evident from the Covid-19 pandemic as a framework for thinking about contact withextraterrestrial intelligence (ETI). The Covid-19 pandemic represents an opportunity to think through challenges that mayarise in response to contact with ETI in part because it represents a potential threat to the entire population of Earth,thus forcing nations to implement similar measures, even if the specifics of those measures and levels of restrictionsvary from one country to another. We argue that contact with ETI will not occur in a political and ideational vacuum. Itwill occur within an historical context and diverse cultural contexts from which people will interpret the import and risksassociated with a contact event. Just as local conditions are influencing the response to Covid-19, governments andpolitical leaders will draw on localized cultural and social conditions as they conduct risk assessments related to ETIcontact and consider the value associated with managing or controlling the context and potential outcomes of a contactevent. Thinking about how governments, in particular, respond to events like the Coronavirus pandemic represents anopportunity to explore how other potential existential threats to global society like contact with ETI might pan out.\nShare this: PDF file, 5 pages: £5.00", "pred_label": "__label__POS", "pred_score_pos": 0.6626582741737366}
{"content": "Transferring schools can be one of the biggest decisions a college student makes. Changing schools can be a challenge both academically and athletically. Being informed is important.\nNCAA transfer rules are a tricky subject – schools must consider the academic impact a transfer student may experience along with the competitive impact a team left behind might feel when a student-athlete leaves for another school. Member schools are regularly evaluating rules to strike the best balance between supporting the student-athletes who wish to transfer and those who remain at their original school.", "pred_label": "__label__POS", "pred_score_pos": 0.9980368614196777}
{"content": "Experimentation plays an essential role in engineering education, allowing to balance theoretical proofs and emphasis on physical intuition. Laboratories can fulfil several goals at once, but they also involve high costs, mostly due to equipment, space, and human resources for operating and maintaining them. Remote-access labs have been proposed as a feasible alternative: developed since the early 2000s by an ever-increasing research community, they are real or virtual labs accessible at distance through a computer network. Recently, alternative bibliometric taxonomies and classifications of current networked remote-access labs have been proposed. Yet, none of these works proposes a comprehensive structure to collect and organize the information, especially from a technical perspective, aiming at the definition of the state of the art and future outlooks of provided solutions. In the present work, we fill this gap extending previous works by enlarging their set of criteria towards a general multi-layer model for networked remote-access labs. We performed a systematic review of relevant literature to retrieve useful information and to design the data collection and classification structure, which is finally validated performing a mini-Delphi method.\nAppare nelle tipologie: 1.1 Articolo su rivista", "pred_label": "__label__POS", "pred_score_pos": 0.9619635939598083}
{"content": "It doesn’t happen often, but on occasion, someone defending against legal action can pass away unexpectedly. In many cases, this ends the legal action. For example, you can’t press criminal charges against someone that is no longer alive. However, it is a bit different with personal injury cases.\nOften if the estate of the deceased is particularly small, the claim will be dropped. However, if the deceased had significant assets in his estate, it is possible for the injured party to continue their personal injury claim, but this time do so against the decedent’s – the deceased party’s – estate.\nWhat this does is grind distributions to heirs to a grinding halt. The estate will need to remain intact until the case has been settled. Once done, the amount from the personal injury case, if successful, will be taken out of the estate. The remainder will then be distributed to the heirs.\nCommonly, this occurs in the event of fatal accidents. For example, if the deceased was negligent for a car accident that killed them, the other injury party could file a personal injury claim against the deceased’s estate. It is a difficult situation for everyone involved. The other injured party may be able to have much of their damages covered by filing a claim with the decedent’s insurance, which is still valid if they passed away. However, they still have the right to file a further claim against the estate of the deceased as insurance may not cover everything.\nAre you in a difficult situation where a loved one has passed away and legal action threatens their estate? We can help. Contact us today to see what Ford + Bergner LLP can do to help you get through this complicated and difficult time with minimal stress over the legal issues.", "pred_label": "__label__POS", "pred_score_pos": 0.8352308869361877}
{"content": "Lani Shiota completed her Ph.D. in Social/Personality Psychology at University of California, Berkeley, in 2003, and then received post-doctoral training in the Berkeley Psychophysiology Lab. She established the Shiota Psychophysiology Laboratory for Affective Testing (a.k.a. SPLAT Lab), which studies human emotions, relationships, and awe. Awe has been defined as the positive emotion one may experience when confronting a vast stimulus that is not accounted for by one's current understanding, and/or challenges one’s day-to-day scope of experience.\nWhat you'll learn in this podcast:", "pred_label": "__label__POS", "pred_score_pos": 0.6974089741706848}
{"content": "Explanations of how organisms might adapt to urban environments have mostly focused on divergent natural selection and adaptive plasticity. However, differential habitat choice has been suggested as an alternative. Here, we test for habitat choice in enhancing crypsis in ground-perching grasshoppers colonizing an urbanized environment, composed of a mosaic of four distinctly coloured substrates (asphalt roads and adjacent pavements). Additionally, we determine its relative importance compared to present-day natural selection and phenotypic plasticity. We found that grasshoppers are very mobile, but nevertheless approximately match the colour of their local substrate. By manipulating grasshopper colour, we confirm that grasshoppers increase the usage of those urban substrates that resemble their own colours. This selective movement actively improves crypsis. Colour divergence between grasshoppers on different substrates is not or hardly owing to present-day natural selection, because observed mortality rates are too low to counteract random substrate use. Additional experiments also show negligible contributions from plasticity in colour. Our results confirm that matching habitat choice can be an important driver of adaptation to urban environments. In general, studies should more fully incorporate that individuals are not only selective targets (i.e. selected on by the environment), but also selective agents (i.e. selecting their own environments).", "pred_label": "__label__POS", "pred_score_pos": 0.5857463479042053}
{"content": "This course aims to bring together Western and Eastern views of Body Movement for Health while offering a pragmatic approach, allowing you to learn and practice your learning at the same time.How to move in harmony\nThe Universe abides by the rule of dynamic adaptability, millions of atoms in constant movement.\nThe human body is no different. We are designed to move, and movement is energy. The way you move has a knock-on effect on your overall health, your physical sensations and more specifically, your emotions. Moving in harmony with these sensations and emotions also helps to safeguard your overall wellbeing.\nHence developing body movement awareness gives you an opportunity to understand your natural capabilities and move accordingly to maximise your health.\nThe reward of experiencing these changes is a more harmonious connection between your body, your mind and your environment, feeling more energised and happier, while enhancing your overall quality of life!\n– Learn and practise your learning with videos, practical exercises, quizzes, observation and reflection times –", "pred_label": "__label__POS", "pred_score_pos": 0.9288198947906494}
{"content": "Kiel,\nReynolds, Jesse (2011): The Regulation of Climate Engineering Reynolds, Jesse (2011): The Regulation of Climate Engineering. In: Law, Inn Tech 3 (1), S. 113–136.\nEssay on (legal) regulation of CE and problems with specific CE methods.\n\"Intentional interventions in global physical, chemical, and biological systems on a massive scale are receiving increasing attention in hopes of reducing the threat of anthropogenic climate change. Known as climate engineering, or geoengineering, research is moving forward, but regulation remains inadequate, due in part to significant regulatory challenges. This essay asserts that key to overcoming these regulatory challenges is distinguishing between the two primary forms of climate engineering, and between deployment and research. One of climate engineering's two primary forms, carbon dioxide removal, can largely be addressed through existing legal instruments. In the case of solar radiation management, the other primary form, focusing initially on research can bypass the geopolitical quagmire of deployment. Two other major challenges to developing regulation for solar radiation management research remain: establishing regulatory legitimacy, and developing an appropriate definition of research. Potential regulatory forms include centralized international legal instruments, fully or partially private transnational networks, and norms developed from the bottom up.\"", "pred_label": "__label__POS", "pred_score_pos": 0.9766528606414795}
{"content": "Towards Positive Change, A Case of the Textile and Garment Industry Bangladesh\nAbstract: In 2013, the Rana Plaza Complex in Bangladesh collapsed claiming the lives of 1134 RMGworkers. This event ignited foreign stakeholders applying pressure on factories within the sectorto uphold adequete safety measures and address concerns over labour rights. The ILO and EUhave since conducted surveys and forwarded recommendations toward what they considerpositive change, in a comittment to improve labour rights and factory safety. (Ashraf & Prentice2019) Prior to this devasting event, women’s rights organisations/movements have and continueto actively challenge cultural and traditional norms in an effort to address issues of social injusticewithin the sector and in society in general. These grievances range from harassment, long hours,fairer wage distribution and equal rights. Currently, 86% of the workforce in Bangladesh workswithin the industry, comprising mostly of women and (children) and is its largest exporter toforeign cloths brands in the West. An estimated 4 million people contribute to this labour forceand since the emergence of the industry in the 1980’s, women have faced various disparities.Women workers have faced conditions which have subjected her to unequal premises and beingless privilaged. An essential part of this inquiry is discussing conceptions of womanhood,empowerment and of gender and class.This DP examines how the Accord, OWDEB and NGWF engage, address and advocate change,together with their representatives. All three stakeholders are striving for positive change withinthe sector, each with a specific focus on areas of concern. This inquiry foremost examines thepush for change.\nAT THIS PAGE YOU CAN DOWNLOAD THE WHOLE ESSAY. (follow the link to the next page)", "pred_label": "__label__POS", "pred_score_pos": 0.5813493728637695}
{"content": "In today’s ever-changing economic, political, and global business environments, diversity and inclusion are important considerations for all organizations. The vision of Diversity in Fund Finance is a Fund Finance (“FF”) community that: (i) recognizes that diverse perspectives strengthen the FF industry and organizations within it, and enhance the ability of those in the FF industry to better serve their clients and colleagues by working together, (ii) is inclusive of diverse individuals across each organization within the FF industry, including at the highest levels of each organization, and (iii) respects the viewpoints and contributions of diverse individuals in their organizations and the FF industry as a whole.\nThe Diversity in Fund Finance initiative is focused in the areas of education, opportunity, action, and affinity, as further detailed below.\nEducation – Part of our mission with respect to education is to educate students about the FF industry, provide opportunities for students to network with industry professionals and facilitate recruitment and retention of students in positions in FF industry organizations. Diversity in Fund Finance recognizes that engagement and relationships need to be built with students early in their careers to create more opportunities to recruit and retain talent to address the current generalized lack of diversity within the FF industry. Opportunity – Part of our mission is also to provide opportunities for would-be and current FF professionals to network, build connections, secure positions and obtain support to progress their careers and advance within their organizations as leaders in the FF industry. Action – We understand that effecting change requires time, shared efforts and new thinking to drive progress. We aim to bring together FF professionals who want to take action to contribute to positive changes, particularly with respect to diversity and inclusion, within the FF industry. Affinity – We provide an open, inclusive, supportive, welcoming, and respectful space for diverse FF industry professionals, students and other would-be professionals in the FF industry to connect based on their shared diverse perspectives and professional experiences. We strive to be inclusive of all diverse individuals, regardless of their culture, race, ethnicity, gender, gender identity, sexual orientation or beliefs.\nFor more information, please contact any of the Co-Chairs of Diversity in Fund Finance, Natasha Puri at Natasha.Puri@lbusa.com or +1 212 895 9538, Anastasia Kaup at ankaup@duanemorris.com or +1 312 499 6767, or Nicki Macgregor at nicki.macgregor@cba.com.au or +1 646 591 8111", "pred_label": "__label__POS", "pred_score_pos": 0.5369492769241333}
{"content": "Keeping Kentucky's Education System Strong\nHow Kentucky’s education standards and aligned assessments are crucial for national security\nWhile you do not often hear the words “national security” and “the Kentucky Academic Standards” in the same sentence, there are a couple of key reasons why they are linked. First, retired military leaders know the standards and aligned assessments are vital for ensuring America has well-educated individuals who are prepared to defend our nation.\nSecond, military families depend on consistent standards for their children, who typically attend schools in many different districts during their K-12 years. Kentucky is home to the 11th largest active military population in the U.S. and has an estimated 25,000 school-aged children whose active duty military parents are temporarily assigned to facilities in the state.\nDifferences in standards and assessments can negatively impact the academic experiences of students who move frequently. Therefore, after careful consideration, the Department of Defense decided to adopt the Common Core for schools they run on military installations beginning in the 2015-16 school year, to “make it easier for students when they relocate to other military or public schools.”\nMaintaining rigorous and consistent academic standards will ensure that students will be better prepared for postsecondary education, the civilian workforce, or the military, if they choose to serve.\nMajor general (Ret.) Michael Davidson, U.S. Army\nFor these reasons and more, the Kentucky Academic Standards and aligned assessments are critical components of an educational experience that prepares young people to meet the demands of the 21st century economy and military.\nKentucky’s Academic Standards (KAS) establish the skills that children must achieve at each grade level. In addition to essential academic content, Kentucky’s Academic Standards focus on critical thinking, complex problem solving, and effective communication—key skills needed in today’s military and many other careers.\nThis report outlines why KAS, along with aligned assessments, are the clearest way to demonstrate Kentucky’s commitment to a world-class education and show measurable results.\nStates", "pred_label": "__label__POS", "pred_score_pos": 0.8702128529548645}
{"content": "A beekeeper captured a heartwarming moment of compassion between insects when he observed an incapacitated bee falling into a honey extractor. The poor bee became covered in honey, so the keeper moved it to the front of his beehive.\nAs soon as the bees realized that one of their own was in danger, they started to help right away, cleaning the honey off of their mate. It took many bees half an hour to clean their friend off, but when they did, its wings were as good as new.\nThe human perception of insects and animals is that they're emotionless creatures with no unique or distinct personalities within their species. However, new studies have demonstrated that even cockroaches have their own unique characters.\nBack, on July 7, 2012, a prominent international team of cognitive neuroscientists, neurophysiologists, neuroanatomists, neuropharmacologists, and computational neuroscientists gathered at the University of Cambridge in order to assess the conscious experience and related behaviors in human and non-human animals. The statement they wrote is known as The Cambridge Declaration on Consciousness.\nThis international team of scientists said that: “Convergent evidence indicates that non-human animals have the neuroanatomical, neurochemical and neurophysiological substrates of conscious states along with the capacity to exhibit intentional behaviors. The evidence consequently indicates that humans are not unique in possessing the neurological substrates that generate consciousness. Non- human animals, including mammals, birds, and many marine creatures, including octopuses, also possess these neurological substrates.”\nIf animals can feel pain, use tools, make choices, and communicate with each other, is it that hard to imagine them as aware, complex beings with feelings and thought processes?\nAnimals and Humans aren't the only conscious beings on this planet, though. Recent studies have discovered that plants have their own form of communication. Researchers with the University of Western Australia discovered that corn plants emit and respond to particular sounds. In their study “Towards Understanding Plant Bioacoustics,” the team discovered that when plants are played a continuous sound at 220 Hz, they grow toward the sound. This frequency range is similar to the clicking sound made by the plants themselves.", "pred_label": "__label__POS", "pred_score_pos": 0.8713524341583252}
{"content": "Abstract\nDuring the past 20 years, the thermoelectric properties of nanostructures such as one-dimensional bismuth (Bi) platforms have prompted the development of a wide variety of nanowire growth methods, aiming to achieve higher energy-conversion efficiency. Most of these methods have demonstrated single-crystal nanowire growth of a quality unmatched in bulk Bi. However, in contrast to the theoretical expectation that Bi nanowires should exhibit high thermoelectric performance, their observed thermoelectric properties have prevented their technological exploitation. Here, we review the current progress in the thermoelectrics of bismuth nanowires, the fundamentals of their advantage and limitation over bulk Bi, and their potential use for enhancing the thermoelectric performance.\nAll Science Journal Classification (ASJC) codes Chemistry(all) Materials Chemistry", "pred_label": "__label__POS", "pred_score_pos": 0.9744179844856262}
{"content": "In May 2010, in a speech before the Council on Foreign Relations, Education Secretary Arne Duncan spoke of the importance of a well-educated citizenry: “America’s success depends on the success of its individual citizens, just as the progress of humanity ultimately depends on the shared progress of nations. I believe that education has immeasurable power to promote growth and stability in the 21st century.”", "pred_label": "__label__POS", "pred_score_pos": 0.9262769222259521}
{"content": "Abstract\nObserved phytoplankton interannual variability has been commonly related to atmospheric variables and climate indices. Here we showed that such relation is highly hampered by internal variability associated with oceanic mesoscale turbulence at middle and high latitudes. We used a 1/54° idealized biogeochemical model with a seasonally repeating atmospheric forcing such that there was no external source of interannual variability. At the scale of moorings, our experiment suggested that internal variability was responsible for interannual fluctuations of the subpolar phytoplankton bloom reaching 80% in amplitude and 2 weeks in timing. Over broader scales, the largest impact occurred in the subtropics with interannual variations of 20% in new production the full strength of this variability could not be captured with the same model run at coarser resolution, suggesting that submesoscale resolving models are needed to fully disentangle the major drivers of biogeochemical variability at interannual time scales. Key Points Submesoscales generate interannual variations in phytoplankton blooms The variability occurs at local scale and translates to larger scale High horizontal resolution is needed to fully capture it\nAll Science Journal Classification (ASJC) codes Geophysics Earth and Planetary Sciences(all) Keywords Bloom chaotic fluxes interannual phenology submesoscale", "pred_label": "__label__POS", "pred_score_pos": 0.6052821278572083}
{"content": "One Housing are a non-profit organization that provide housing, maintenance, care, and support for people in the UK who struggle to find a place to live. The majority of their employees work remotely in communities with residents and therefore rely on mobile devices to communicate and record data. This provides convenience and flexibility for the employees, however it can also result in inflated data bills for the organization.\nCorrata has given us predictability of our mobile data spend and saved us money from month one.\nCharles Hall, Financial Controller\nThe solution\nControlling data usage and reducing costs was the number one priority for One Housing when they contacted Corrata. The organization lacked the ability to track and identify high usage events or offenders and were also unable to impose controls or restrictions to manage data consumption and associated costs.\nData Usage Control from Corrata gave One Housing visibility over mobile data usage across their entire mobile estate via the Corrata Console. This enabled administrators to track data usage in real time, receive alerts and quickly resolve potential bill shock events. The ability to apply monthly or daily data usage limits to individual employees while domestic or roaming, block high-bandwidth apps such as Netflix and YouTube, and permit business critical apps was essential. One Housing saw significant data usage changes immediately resulting in a significant reduction in mobile data plan costs and elimination of bill shock events.", "pred_label": "__label__POS", "pred_score_pos": 0.8555712699890137}
{"content": "Chronic Illness & Complex Medical Conditions\nNavigating chronic illness can feel like being in a tiny skiff on a roiling sea. The client and his or her family can experience a whole range of stressors including anticipatory grief, struggles with maintaining pre-illness identity, depression resulting from missing out on normal activities, and irritability from coping with persistent pain. It can be hard to find joy and fulfillment in circumstances like these—but, with the help and support of our skilled team, you can work toward healing psychologically, regardless of your ailment. In many cases, this psychological healing can create a positive feedback loop that actually improves the underlying physical condition. This is an empowering and life-changing experience, and one we are honored to facilitate.\nHow it works Book your free phone consultation\nTake our quiz to find the therapist who’s right for you and book a free 15-minute phone consultation.\nGet familiarized with the process\nDuring your phone consultation, your therapist will answer your questions and schedule your first visit.\nAttend your first appointment\nYour therapist will get to know you and offer a supportive plan to help you reach your goals.", "pred_label": "__label__POS", "pred_score_pos": 0.5612499713897705}
{"content": "Water Safety\nLead-contaminated dust is the most common source of lead exposure.\nOlder homes may contain lead pipes or faucets that can contribute to lead exposure. When lead pipes are moved or worked on near your home or within your home, lead may leach into the water as it passes through the pipes.\nIf you have lead pipes, consider cleaning the aerator, flushing the water lines, and/or using a filter that is certified by the National Sanitation Foundation (NSF) for lead removal. For more information, see the resources below.\nDRINKING WATER SUPPLIES IN KENT COUNTY\nYour water is either from a public water supply or from a private well. If you get a bill for your water, you are on a public water supply. Public water suppliers are required to test household water for lead. The same requirement does not apply to private wells.\nTo ensure drinking water is safe, public water supplies throughout Kent County are sampled under the Safe Drinking Water Act for compliance with the Lead and Copper Rule. These water sources are closely monitored by the Kent County Health Department and the Michigan Department of Environment, Great Lakes, and Energy (EGLE). If your water is from a well, you are encouraged to test it for lead. For testing, contact the Kent County Health Department lab at 616-632-7210.", "pred_label": "__label__POS", "pred_score_pos": 0.6395174860954285}
{"content": "Based on mouse studies, AURKA (STK15) was identified as a candidate skin tumor susceptibility gene. STK15 is frequently amplified in human colon cancers and other tumor types. The authors identified the STK15 91T->A variant and showed “statistically significant allele-specific amplification of the 91A allele (P = 0.018, chi squared test), providing additional evidence for the role of this allele in human cancer”. Individuals with even one copy of the 91A allele develop tumors with a higher degree of aneuploidy than homozygous 91T individuals.\nMeta-analysis confirmed that the 91A polymorphism is a low-penetrance cancer susceptibility allele in several cancer types, with greater risk for the 91A homozygotes. When the results were combined in a meta-analysis, the authors “found an OR of 1.4 for the T+91A homozygotes (95% CI of 1.22—1.59, P-value < 0.001)” and a “modest but significant increase in risk in the T+91A heterozygotes (OR = 1.10, 95% CI 1.03—1.18, P-value = 0.006)”.", "pred_label": "__label__POS", "pred_score_pos": 0.6914022564888}
{"content": "U.S. Dollar Strengthens While Pound Slumps\nTuesday saw the U.S. dollar strengthen versus other major currencies as the markets waited for the Fed decision regarding rates. The pound sterling, on the other hand, kept falling as concerns over the potential chaos of a no-deal Brexit grew.\nThus, the U.S. dollar index was 97.877, equating to an increase of 0.1%.\nThe Federal Reserve will be meeting to discuss monetary policy starting on Tuesday for two days. On Wednesday, analysts expect the Fed to announce a rate decrease of at least 25 basis points.\nWhile there was a lot of support for the idea that the Fed’s rate cut would be 50 basis points, it is believed far less likely now thanks to positive data, including good U.S. GDP figures.\nThe USD was further strengthened by a significant increase in June’s pending home sales, along with positive consumer confidence figures in July.\nThe U.S. dollar gained ground versus the Japanese yen, with the USD/JPY trading at 108.58, showing a decline of 0.2%. The JPY weakened on the back of the Bank of Japan’s decision to maintain the interest rate at current levels, but revision their inflation predictions downwards.\nPound Slumps as Markets Fear a No-Deal Brexit Will Cause Global Chaos\nThe pound hit its lowest level since March 2017, trading at $1.2120. Since Boris Johnson took over as Prime Minister, the pound has declined by $0.036.\nJohnson has repeatedly stated that he was willing to go through with a no-deal Brexit, and markets now fear the chaos that would result from this move.\nThe pound has been a slave to any news surrounding the Brexit since the EU referendum was held in 2016. The pound had its most significant decline in one day since the early 1970s after the result of the referendum was publicized.\nING issued a note to their clients warning them that the pound would likely experience even more weakness in the near future. The bank’s analysts feel that the pound will continue to decline, mainly due to the uncertainty surrounding Brexit, but also the increasing likelihood that early elections will take place.\nBoris Johnson has stated that he will negotiate a new deal with the EU and plans to boost the U.K.’s economy after what he dubbed the “gloom” of Theresa May’s stint as PM.\nDespite Johnson’s veiled threats towards the EU that he was willing to remove the U.K. from the union without a deal, the European Union has stated they are unwilling to change the terms already negotiated with Theresa May.\nIn an attempt to garner further support, Johnson as embarked on a tour of the country. Thus, on Monday, while in Scotland, he told the press that he wanted to negotiate a new deal, but, at the same time, preparations must be made for a no-deal Brexit.\nWhat concerns investors is the potential shockwave that could affect the global economy if the U.K. left the EU without a deal. It could also potentially push the British economy into a recession, cause upheaval in the financial markets, and London’s position as the most important international financial hub would weaken.\nHowever, those in favor of Brexit believe that the short-term difficulties would be outweighed by the long-term benefits. Furthermore, they feel that the potential problems resulting from a no-deal Brexit have been greatly exaggerated.\nTuesday saw Boris Johnson attempt to draw British farmers to his side by promising they would receive better conditions and deals once the U.K. was out of the European Union. He stated that he fully backed British farmers and wanted to ensure that the Brexit would be beneficial for them.\nOne serious problem in any potential negotiations between the U.K. and the EU is the Irish backstop, which is meant to prevent the installation of a hard border between the Republic of Ireland and Northern Ireland.\nJohnson is adamant that the backstop is removed, or he won’t return to the negotiating table. The EU, on the other hand, refuses to back down. Thus, a no-deal Brexit is becoming increasingly likely, and the pound will continue to suffer as a result.", "pred_label": "__label__POS", "pred_score_pos": 0.7975437045097351}
{"content": "Helping sports clubs change the game: Part two Why sports brands need to think about fan behaviour\nIn helping sports clubs build deeper engagement with their spectators, we need to think about what sports clubs can offer their audience and also how those watching can contribute to the experience.\nTo do this, we need to take into account how spectators are likely to behave in this setting; in a predictably irrational way. This will differ by sport, by team, by individual event. Even for each individual fan.\nBut what the ‘right’ fan experience needs to achieve is consistent; fostering that passion and belonging that underpins ongoing engagement. Getting the stadium experience ‘right’ rests on the balance between two complimentary factors:\nIdentifying and facilitating the ‘right’ behaviours– promoting a positive, vibrant atmosphere that supports a sense of participation and belonging while… Softening (or removing) the ‘wrong’ behaviours– challenging anti-social and negative behaviours that contribute to divisions amongst the fans\nThis doesn’t mean telling people how they should (or shouldn’t) behave.\nIt’s about encouraging and creating an environment within stadiums that supports a sense of belonging and participation for everyone to flourish in.\nWe understand how to leverage behavioural economics to overcome these barriers\nBy understanding behavioural ‘rules of thumb’ (heuristics) that spectators hold, we can determine what causes biases that result in these negative behaviours which hinder deeper fan engagement.\nWith this knowledge we can investigate, test and create effective ways to intervene and change behaviour.\nWe’ve applied this expertise across different industries including sport; just see how we’re helping The FA to challenge anti-social behaviours amongst away fans\nhere.", "pred_label": "__label__POS", "pred_score_pos": 0.577569842338562}
{"content": "LAS Group has submitted plans for a significant revitalisation of Northcote Plaza, which will see two strata titles within the precinct transformed into a new mixed-use town centre called Northcote Green.\nThe $500m Northcote Green precinct has been designed primarily to enhance and improve the local amenity, delivering a gym, extensive green corridors and connective links, new dining and café tenancies, community pop up activation areas, a community amphitheatre, activated laneways and improved access throughout the precinct.\nThe existing retail offering in Northcote Plaza will also be strategically re-weighted and re-positioned under the proposed redevelopment, with the current percentage of food and beverage tenants set to double from 4.3 per cent to 8.6 per cent, in a move to improve footfall and dwell times within the centre.\nThe project is expected to generate an additional $21 million in additional retail expenditure in coming years once complete, according to economic modelling by Macroplan commissioned by the developer, with the significant economic windfall created by Northcote Green, along with the creation of approximately 600 short-term construction jobs and 500 ongoing positions, set to play a positive role in the local area’s economic recovery from COVID-19.\nLAS Group managing director Les Smith said the proposed redevelopment would bring much-needed new life to the ageing retail hub.\n“ Northcote Plaza has held an almost iconic status in the community for almost 40 years. We see this as an opportunity to reinvigorate and revitalise the precinct to deliver upgrades to the existing infrastructure while adding significant amenity and new community facilities.\n“ Our vision for the strategic redevelopment and re-alignment of the tenant mix within the centre, along with the delivery of extensive public amenity and community facilities, is to create more reasons to visit the precinct and deliver more benefit to both existing traders and the local community,” he said.\nDue to the site’s unique individual strata titling, Northcote Plaza’s existing trader footprint will remain largely unaffected by the proposed redevelopment and will continue to trade as normal throughout construction.Northcote Green’s announcement follows the commencement of construction at LAS Group’s One Wellington project in St Kilda, a 50-50 joint venture with real estate powerhouse Qualitas, which will bring 252 build-to-rent apartments to one of Melbourne’s most sought-after locales.", "pred_label": "__label__POS", "pred_score_pos": 0.6530873775482178}
{"content": "Alysia Gradney, Principal\nThe Gudz 832-263-1714 alysia@thegudz.com\nInstitute targeting Black STEM professionals, tech startups, and government officials launches #BlackTechPolicy Week, a virtual event on December 1 – 5, 2020\n(Black PR Wire) #BlackTechFutures Research Institute opens registration for its first-ever #BlackTechPolicy Week. Funded in part by an Ewing Marion Kauffman Foundation Knowledge Challenge award, granted to Stillman College School of Business and Dr. Fallon Wilson, #BlackTechPolicy Week will explore the challenges and opportunities municipalities and organizations encounter when building equitable tech policies, and the impact of these policies on Black lives.\nAmid the U.S. presidential transition period, #BlackTechPolicy Week places Black lives at the epicenter of AI ethics, EdTech, VC investments into tech startups, privacy, bridging the digital divide, and more. The week-long engagement will bring together technologists, higher learning institutions, professional and affinity groups, entrepreneurship organizations, government officials, community organizers, private foundations, tech startups, urban planners, faith leaders, and local organizations.\n\"By placing the value of Black futures at the center of technological development and advancement, #BlackTechPolicy Week will serve as the birthing ground for innovative policies and strategic networking,\" said Dr. Fallon Wilson, Co-Founder of #BlackTechFutures Research Institute. \"Our goal is to unite scholars, practitioners, and community activists in a dialogue—a movement—to grow tech equity at the hyper-local level.\"\nLaunched in 2020, the #BlackTechFutures Research Institute serves as a long-term educational initiative housed at Stillman College, a Historically Black College and University (HBCU). The institute is positioned to build a national network of city-based researchers and practitioners researching sustainable local Black tech ecosystems. The outcomes of this work are to develop a national public data archive and create actionable policy recommendations at municipal, state, and national levels. #BlackTechPolicy Week serves as the institute's first public engagement opportunity.\nFor nearly 150 years, Stillman College has been a creator and advocate of inclusive and equitable environments for Black people. Dr. Cynthia Warrick, Stillman’s first female President, continues that legacy in the 21st Century through innovation and technology.\n\"To proactively increase the participation of Black technologists, it is imperative we identify, engage, educate, connect, and support scholars and practitioners in technology,\" states Isaac McCoy, Dean of the School of Business at Stillman College. \"Not only is this work important, but it's critical to the equitable advancement of Black people in a digital world.\"\n#BlackTechPolicy Week includes three panels, free and open to the public, where participants will hear directly from Black tech leaders in multiple sectors. This year's sessions include:\nA National Black Tech Policy Agenda: December 1, 2020, at 6:00 pm/CST Black Public Interest Technologists: December 3, 2020, at 6:00 pm/CST Organizing Black Tech Communities Online: December 4, 2020 at 6:00 pm/CST Supporting Local Black Tech Ecosystems: December 5, 2020, at 10 am/CST\nParticipants will hear from the nation's top technologists, politicians, entrepreneurs, community organizers, medical professionals, and more. This year's #BlackTechPolicy Week speakers include:\nRev. Leah Daughtry, Black Church PAC Clint Odom, National Urban League Dr. Nicol Turner Lee, Brookings Institute Chris Lewis, Public Knowledge Dr. Andre Brock, Georgia Institute of Technology Maurita Coley, Multicultural Media, Telecom and Internet Council (MMTC)\nTo register and learn more about the institute, visit blacktechfutures.com.", "pred_label": "__label__POS", "pred_score_pos": 0.5763214826583862}
{"content": "A notable number of federal student loan borrowers struggle to make payments. While most have heard about income-driven repayment (IDR) plan options many don't know where to start.\nThis step-by-step guide walks borrowers through the free process of applying for IDR through the U.S. Department of Education's Federal Student Aid website. Use this resource for your own education or share with student loan borrowers directly.\nEnter your contact information to download this resource.\nFind additional resources at our Definitive Guide to Default Prevention page.", "pred_label": "__label__POS", "pred_score_pos": 0.7561250925064087}
{"content": "Insights to help you mitigate the risks associated with Coronavirus\nWhile the primary focus of any business will be on ensuring the health and wellbeing of staff, businesses are facing an increasing number of challenges that need to be addressed and mitigated. The legal implications are wide-ranging and complex.\nHere we bring together the practical considerations and insights into critical questions and from across different jurisdictions to help businesses manage and mitigate risk.\nHow can our lawyers help you to navigate through this period?\nWe can help you identify the risks, provide options and discuss various legal remedies, advise on the measures being taken by various governments, provide insight from an industry perspective, consider the supply chain and regulatory challenges, help you plan your response and minimise the threat of disputes.\nWe understand that you need strategic, cross-jurisdictional advice from experts who can help you respond quickly to the emerging crisis. Please get in touch with your usual Clifford Chance contact.", "pred_label": "__label__POS", "pred_score_pos": 0.6931275129318237}
{"content": "Background: Childhood maltreatment has been associated with significant impairment in social, emotional and behavioural functioning later in life. Nevertheless, some individuals who have experienced childhood maltreatment function better than expected given their circumstances. Main body: Here, we provide an integrated understanding of the complex, interrelated mechanisms that facilitate such individual resilient functioning after childhood maltreatment. We aim to show that resilient functioning is not facilitated by any single ‘resilience biomarker’. Rather, resilient functioning after childhood maltreatment is a product of complex processes and influences across multiple levels, ranging from ‘bottom-up’ polygenetic influences, to ‘top-down’ supportive social influences. We highlight the complex nature of resilient functioning and suggest how future studies could embrace a complexity theory approach and investigate multiple levels of biological organisation and their temporal dynamics in a longitudinal or prospective manner. This would involve using methods and tools that allow the characterisation of resilient functioning trajectories, attractor states and multidimensional/multilevel assessments of functioning. Such an approach necessitates large, longitudinal studies on the neurobiological mechanisms of resilient functioning after childhood maltreatment that cut across and integrate multiple levels of explanation (i.e. genetics, endocrine and immune systems, brain structure and function, cognition and environmental factors) and their temporal interconnections. Conclusion: We conclude that a turn towards complexity is likely to foster collaboration and integration across fields. It is a promising avenue which may guide future studies aimed to promote resilience in those who have experienced childhood maltreatment.\nIoannidis, K., Askelund, A.D., Kievit, R.A.\net al. The complex neurobiology of resilient functioning after childhood maltreatment. BMC Med 18, 32 (2020).", "pred_label": "__label__POS", "pred_score_pos": 0.9979021549224854}
{"content": "IASB trustees will undertake a constitution review\n07 Nov 2003\nAt their meeting in Brussels on 4 November 2003, the trustees of the IASC Foundation (which oversees the IASB) announced the appointment of a committee to review the IASB's constitution.\nAt its 3 November 2003 meeting, the constitution review committee felt it was important to announce the existence of the committee. The procedures and timetable were also decided. Meetings would generally be open, with proposals published prior to decisions being made. A list of topics to be examined will be issued quickly without comment on the relative importance of each, though the committee recognised that some additional questions might arise in the course of their work.\nThe committee felt that transparency is essential. The trustees discussed staffing for the review and concluded that at most one additional staff member could be funded. They discussed, without conclusion, whether there should be an advisory board. While such a board would provide a good sounding board, some trustees were concerned that an advisory board might assume some of the power of the review committee itself. The matter of duplication of effort of the review committee and the advisory board was also discussed.\nTrustees noted that the Constitution is detailed and rule based. They discussed whether it provides for sufficient representation by analysts and preparers of accounts. They noted that it is sometimes difficult to get these parties involved in IASB activities and that this issue can not be resolved in the constitution.\nTrustees noted that the constitution includes a list of organisations which the IASB should consult, but some important groups (such as the Basel Committee) are not included. However the IASB Chairman noted that while the wording needed to be altered slightly, the list was not meant to be exhaustive and did not preclude consultation with other groups.\nWe have created a new Page on IASPlus to track the progress of the constitution review.", "pred_label": "__label__POS", "pred_score_pos": 0.6097867488861084}
{"content": "A display technology developed at the Korea Electrotechnology Research Institute (KERI) produces 3D pixels with nanoscale dimensions by 3D-printing quantum dots (QDs) embedded in polymer nanowires. The technology — called “nanophotonic 3D printing” by the research team — could be used to achieve superhigh-resolution displays in TVs, smartphones, virtual reality headsets, and other devices. The more pixels on a display screen and the more densely the pixels are integrated, the higher the resolution. To increase the number of pixels that can appear on a screen, the traditional approach has been to reduce the pixel size. Achieving a higher definition through a smaller pixel size has become a key to leading in this competitive market, but reducing pixel size can also limit light intensity. A South Korean research team developed a technology to produce a nanodisplay with a superhigh resolution based on a 3D-printing technique. Courtesy of Korea Electrotechnology Research Institute (KERI). The KERI team believed that the light intensity required for a superhigh resolution could be achieved by producing pixels with a 3D structure. Instead of using a 2D patterning approach, the team applied a 3D structure to its pixels to overcome light intensity issues. The 3D layout enabled a twofold increase in brightness with full colors (red, green, blue), compared to conventional thin-film-based structures, and had no significant effects on the spatial resolution. Using its nanophotonic 3D-printing technology, the team demonstrated the production of pixels with a lateral dimension of 620 nm and a pitch of 3 μm for each of the red, green, and blue colors. The researchers demonstrated the three primary colors in 5600 pixels per inch (PPI), exceeding that of 8K QLED TV (100 PPI), laptop (200 PPI), and smartphone (800 PPI) devices, while surpassing the limit of commercial technology (1000 PPI) by five times or more. The team also demonstrated individual control of the brightness based on a simple adjustment of the height of the 3D pixels. The pixel density provided by the KERI team’s approach could be applied to future displays for VR and AR, beam projectors, and other applications requiring superhigh resolution. One of the biggest benefits of the nanophotonic 3D-printing technology, the researchers believe, is that the QDs can be 3D-printed onto polyimide or polyethylene terephthalate materials, which are used to produce flexible substrates. This could allow the technology to be used for wearable or rollable devices. The research was published in ACS Nano (www.doi.org/10.1021/acsnano.0c04075).", "pred_label": "__label__POS", "pred_score_pos": 0.6569631695747375}
{"content": "COLUMBUS, Ohio, August 2019 – Back-to-school season is upon us, and UCT has gotten into the spirit by collecting and distributing over 15 bags of supplies including spiral notebooks, pencils, crayons, calculators, glue, and even backpacks for students at Livingston Elementary School in Columbus.\nLivingston Elementary School’s nearly 450 students in grades PK-6 includes individuals with developmental handicaps and learning disabilities, children with multiple disabilities, and gifted and talented students. The donated supplies will benefit all students since the school has a community supply system, which means all supplies are shared by everyone. This system helps students learn how to share and cooperate; it cuts down on competitiveness and one-upmanship; and it ensures that all students have what they need to get the most out of their school experience.\nUCT has three local councils in Columbus that support a number of worthy causes in the central Ohio area, including the Mid-Ohio Foodbank’s Operation Feed, United Way, Faith Mission, Special Olympics, The ARC and Ronald McDonald House.", "pred_label": "__label__POS", "pred_score_pos": 0.7994821667671204}
{"content": "The demands you face as a healthcare executive are continually growing. Adopting population health strategies presents challenges to running your own organization, while at the same time you may be asked to partner with others to address the social needs of your community. The initiatives you undertake to enhance community health may require changes in healthcare delivery. You may also find yourself leading a community healthcare program. This interactive seminar will help prepare you to lead your organization in its new role as a steward of health, and it will provide the foundation for designing and adapting to a community-oriented healthcare model.", "pred_label": "__label__POS", "pred_score_pos": 0.9925832748413086}
{"content": "The Non-user Fallacy: How Abreva Leveraged Loyalists to Convert Non-users\nAt the time when GSK engaged with Brandtrust, the Abreva team possessed considerable knowledge regarding the category and consumer’s needs and motivations. However, the brand did not understand the disconnect between non-users desires for treatment and the rationalizations at shelf to choose less expensive, second tier brands. Why was the Abreva team missing the mark with non-users when all signs pointed to ‘yes’? They were chasing the wrong idea and asking the wrong questions.\nWhile a typical approach would focus on studying non-users and uncovering their attitudes toward the brand and their rationale for not using the brand, Abreva partnered with Brandtrust to understand how and why non-users became users. By focusing on those who currently use the brand, the brand was able to not only uncover what obstacles prevent non-users from trial but also what motivates non-users to move into trial.\nThis webinar features guest Elizabeth Latoracca, Global Insights Director of Pain Management at GlaxoSmithKline, and Brandtrust’s own Kristian Aloma.", "pred_label": "__label__POS", "pred_score_pos": 0.9844172596931458}
{"content": "*SOC Code (Standard Occupational Classification): 7122\nDebt, rent and other cash collectors collect payments due or overdue from households and businesses and empty cash from prepayment meters or machines.\nCommon tasks include:\nNo academic qualifications are required. Training is typically provided on-the-job. This may be supplemented by specialised training courses within larger agencies.\n*Introduced in 1990, SOC is a multi-purpose common classification of occupations in UK. Jobs are defined in terms of skill level and skill content, including qualifications, training and work experience.\nBreaking down the official government big data sources by gender, age and region. Hours and pay data based on full time equlivalent roles.", "pred_label": "__label__POS", "pred_score_pos": 0.5006893873214722}
{"content": "Police are investigating the tragic death of a young man who was murdered in Florida Monday afternoon. Authorities identified the victim as 19-year-old Jeffrey Marlin Dumersaint. The incident occurred at a gas station near the border separating Miami-Dade and Broward counties on August 17 around 3:30 p.m.\nMiami-Dade Police arrested the shooter, who was identified as 32-year-old Robert Caleb. According to a local news report, Caleb and Dumersaint were engaged in an altercation at the 7-Eleven gas station store on 1000 NE 215th Street when Caleb withdrew a semiautomatic handgun from his backpack and repeatedly shot at Dumersaint, fatally wounding him.\nAfter the shooting, Caleb fled the scene but was apprehended by authorities a few blocks south of the store. In the arrest report, Caleb alleges he was walking toward the 7-Eleven when he was almost struck by Dumersaint’s vehicle. He claims this was what led to the argument and subsequent shooting.\nTwo other vehicles were involved in a collision outside the store while attempting to evade the gunfire. Fortunately, the occupants did not sustain any injuries.\nCaleb is now facing first-degree murder charges.\nWhat It Means to Be Charged With First-Degree Murder in Florida\nIn Florida, first-degree murder is considered a capital felony, meaning it is among the most severe of all criminal charges and carries some of the strictest penalties of all crimes committed in the state. Those who are found guilty can be sentenced to life in prison, or worse, may even face the death penalty.\nHowever, just because a person is charged with first-degree murder doesn’t mean they will automatically receive an extreme sentence. Under certain circumstances, penalties may be reduced, but not without the help of an extremely experienced criminal defense lawyer.\nThe Benefits of Hiring a Skilled Criminal Defense Lawyer\nIf you were arrested on first-degree murder charges in Florida, a knowledgeable legal team, such as the criminal defense lawyers at Michael D. Weinstein, PA, can represent your case and ensure you are given due process. Your attorney will investigate the circumstances surrounding the incident, interview authorities and witnesses, have all forensic evidence properly analyzed, and, ultimately, do everything in their power to protect your rights.\nDepending on the specific details of the incident and what your attorney uncovers, your charges may be reduced to second- or third-degree murder or manslaughter. In some circumstances, a plea deal can be entered to further reduce the penalties. Those who are wrongfully accused of committing murder may even be acquitted of the charges.\nAnyone who has been accused of a crime has the right to retain legal counsel. The accused or their loved ones should always acquire an attorney who focuses on criminal defense to ensure their legal counsel has the specific skills and experience needed to successfully contest the charges in court.", "pred_label": "__label__POS", "pred_score_pos": 0.9314638376235962}
{"content": "Mechanical properties\nWe carry out macroscopic deformation experiments in compression using a ZWICK Z050 testing system, equipped with a high-temperature furnace (up to 1200 °C), a high-precision strain gauge (± 10 nm) and a video system for in-situ sample monitoring during deformation.\nThe group has long standing expertise in the analysis of mechanical testing experiments including incremental testing (e.g. stress-relaxation, temperature cycling, etc.) to determine thermodynamic activation parameters of the deformation process. We characterize the microstructure of deformed materials in depth, employing the transmission electron microscopes of the Ernst-Ruska Centre, and applying techniques such as Bragg-contrast imaging, Convergent Beam Electron Diffraction, and high-resolution imaging.\nParticular achievements of the group are the consistent characterization of quasicrystal plasticity in terms of a cluster friction model, and the discovery of metadislocations, a novel class of defects enabling plastic deformation of complex, large unit-cell materials. Currently we are focusing on the mechanical characterization of high-entropy alloys.\nM. Feuerbacher.\nDislocations in Icosahedral Quasicrystals Invited Review. Chem. Soc. Rev. 41, 2012, 6745. H. Klein, M. Feuerbacher, P.Schall and K.Urban. A novel type of dislocation in an Al-Pd-Mn quasicrystal approximant, Phys. Rev. Lett, 82 1999, 3468. M. Heggen, L. Houben, M. Feuerbacher. Plastic deformation mechanism in complex solids Nature Materials 9, 2010, 332.", "pred_label": "__label__POS", "pred_score_pos": 0.6125702857971191}
{"content": "Leasing an apartment can be a time-intensive proposition, particularly in situations where landlords require a variety of supporting information to ensure that you, the future tenant, do not pose a legitimate financial risk. Following employment verification, credit checks and reference evaluations, a landlord may still require that the tenant find a co-signer to support their application. Generally, this person has a more reputable financial history and acts to support an otherwise weak leasing application. In the event that the co-signer is located out of state, the landlord may choose not to allow them to attach their name to the application.\nTips\nLegally, an individual residing in a different state than a prospective tenant may act as their co-signer. However, it is ultimately the decision of the landlord as to whether or not they will allow this.\nThe Basics of Co-Signing\nAs mentioned previously, the role of the co-signer is to act as a second funding source in the event that the primary applicant is unable to meet the terms of their leasing obligation. Applicants who meet or exceed the financial standards established by the landlord will not be required to find a co-signer. Those who do not, however, will most likely be forced to use co-signer or withdraw their application.\nThe individual who chooses to co-sign on the leasing application assumes a variety of risks and responsibilities. In the event that the primary applicant is unable to meet the terms of the loan, it will become the duty of the co-signer to pay the rest of these financial obligations. Failure to do so could negatively impact the credit score of the co-signer, even though they never actually lived in the property in question. Simply put, all of the duties assigned to the original application will be transferred to the co-signer if the original tenant is unable to fulfill them.\nOut-of-State Cosigner Apartment Considerations\nBecause of the fact that the co-signer will carry the burden of the lease, many landlords require that these individuals reside in the same state as the primary applicant. Debt collection could be significantly more complex in situations where the co-signer is not located in the same state as the primary applicant. These logistical factors will commonly persuade landlords to implement an in-state requirement for these individuals.\nThat being said, this is not always the case. Given the fact that this requirement is discretionary, specific policies referring to co-signers and their current place of residence is entirely left to the landlord.\nEvaluating Potential Options for Co-Signers\nAs a loan co-signer and landlord alike, the best way to avoid a potentially negative situation is to remain in close contact with one another. For example, a loan co-signer may ask that the landlord contact them in the event that the tenant is late on rent or fails to pay entirely. Tactics such as these will help minimize the overall risk of the primary tenant forfeiting their contractual requirement and passing them on to the co-signer.\nAlthough a co-signer may feel some form of obligation to support a close associated with their application, it is important to remember that this should be the most objective decision possible. Acting as a co-signer carries serious financial obligations and potential consequences. If the original applicant has not displayed the degree of financial responsibility needed to inspire the necessary confidence, co-signing is not advised.\nReferences\nWriter Bio\nRyan Cockerham is a nationally recognized author specializing in all things innovation, business and creativity. His work has served the business, nonprofit and political community. Ryan's work has been featured at Zacks Investment Research, SFGate Home Guides, Bloomberg, HuffPost and more.", "pred_label": "__label__POS", "pred_score_pos": 0.7448407411575317}
{"content": "Abstract\nDiet and exercise have been shown to have significant importance in predicting both physical and psychological well-being. However, there is little empirical evidence examining the effects of regular practices which encourage awareness on an individual’s health-related identity and self efficacy. This study examined the effects of a daily awareness-based intervention on health-related identity and self-efficacy. Fifty-four adults were allocated into either an 8-week control (n=25) or intervention group(n=29) and all completed a battery of measures designed to assess their health-related identity and self-efficacy. The intervention group were sent a daily email reminder for 8 weeks to log on to a computer website and answer a series of reflective questions. These questions related to the quality and volume of food and liquids consumed throughout the day, their mood, the type, intensity and duration of exercise which they engaged in throughout the day, and the amount of paid or unpaid work hours which they were engaged in throughout the day. Finally, participants were asked daily whether they aimed to achieve balance in any of their regular roles.The control group did not engage in any intervention during the 8-week phase. The ‘daily diary’ website and questions aimed to promote awareness of health behaviours, and results indicated the intervention group displayed a significant improvement in all variables, when compared with the control group.\nOriginal language English Pages (from-to) 14-28 Number of pages 15 Journal Graduate Journal of Sport, Exercise & Physical Education Research Volume 4 Publication status Published - 2016", "pred_label": "__label__POS", "pred_score_pos": 0.861557126045227}
{"content": "Trading Updates 14/02/2020\nTrading Update - 14 February 2020\nFurther trades have taken place in the funds in February 2020.\nFollowing the rally in risk asset prices we have top sliced our exposure to equities somewhat; reducing exposure to passive vehicles replicating indices in European, Emerging market and US equities. This is a tactical move reflecting the risks that (a) the near term economic impact of the novel Coronavirus may be greater than currently priced in, and (b) reported infections outside China could start to accelerate.\nIn cutting our equity exposure, we have reduced our positions in Sterling hedged share classes in order to reflect the view that the differences between the UK and European Union Brexit negotiating positions will be thrown into sharp relief over the next month or so, and this could undermine Sterling.\nProceeds raised have been used to increase exposure to infrastructure, gold and cash.\nPurchase – TwentyFour Income Fund\nWe have purchased the TwentyFour Income Fund, a London-listed closed-ended investment company focusing on European asset-backed securities, for the Managed Income and Defensive funds.\nWe believe the European structured credit market currently offers standout absolute and relative value within global credit markets. The £645m company, which originally listed on the main market of the London Stock Exchange in 2013, is managed by the highly regarded ABS team at TwentyFour Asset Management and has delivered attractive returns to shareholders since launch.\nThe underlying portfolio comprises investments issued by banks and other financial institutions that are principally secured against UK and EU residential mortgages and corporate loans, and generates a floating rate income yield in excess of 7%. The company aims to generate net total returns of 6-9% per annum and a pay a minimum dividend yield to shareholders of at least 6%.\nCornelian Investment Team", "pred_label": "__label__POS", "pred_score_pos": 0.5698246359825134}
{"content": "Pineapple & asthma Pineapples may have more than just taste benefits, as they are also helpful in reducing asthma.Updated: Sep 04, 2004, 12:09 IST\nPineapples may have more than just their tasty benefits, as they have now been found to be helpful in reducing asthma.\nA study conducted by Eric R. Secor of the University of Connecticut, has revealed that bromelain derived from the stem of pineapple plant is effective in reducing inflammation associated with asthma.\nDuring the experiments conducted on mice, Secor found that bromelain treatment significantly reduced the total white blood cell count, which increases with the onset of asthma and reduced the formation of cell markers for inflammatory asthma.\nHow exactly bromelain works is not yet determined.However, the study could offer a significant breakthrough in the treatment of a pulmonary disorder that continues to harm millions of people across the world.", "pred_label": "__label__POS", "pred_score_pos": 0.9074925780296326}
{"content": "Phoenix residents who find themselves operating their vehicles near semi-trucks can wind up nervous. This is usually because they know that one minor mistake on a trucker’s part can cause serious damage, leaving them with serious injuries. All too often this fear becomes a reality. In these situations, car accident victims can struggle to find a way to overcome their injuries, regain their physical capabilities, recover their financial losses, ease their emotional trauma and obtain a sense of justice.\nFortunately, a personal injury lawsuit could help achieve all of these goals. Yet, when a car accident involves a semi-truck, matters can quickly become complicated. One reason is because it is often difficult to determine which parties can be held accountable. Although an errant trucker is almost always on the hook, it may be unclear as to whether a truck company can be held liable. While the legal theory of “vicarious liability” says yes, with some exceptions, those lines can become blurred when truckers are owners and operators, or when they are carrying a load that belongs to a party separate from the truck company.\nEvidentiary issues can arise in these cases, too. Even though truckers keep logs, truck companies retain maintenance records and truck data including speed is stored, this evidence can and sometimes does conflict with other evidence. This can present problems that can be challenging to overcome if a victim doesn’t know how to utilize the law to his or her advantage.\nTo best develop a legal claim against a trucker and/or truck company, accident victims need to thoroughly prepare their legal arguments while anticipating the defense’s strategy and objections. This can be a daunting process. This is why many accident victims get further legal information to assist them in their fight for compensation.", "pred_label": "__label__POS", "pred_score_pos": 0.5077464580535889}
{"content": "Types of Mouth Injuries\nAn injury to lips can be due to a fall, resulting in cuts to the upper or lower lips of kid. If the wound is severe, it affects deeper tissues of the lip, such as muscles, nerves, or blood vessels.\nWhen a child falls with a pointed object such as pencil or tooth brush in the mouth it causes severe wound in the back of the throat and soft palate.\nTongue wound usually occurs after an accidental bite during eating or a fall.\nMost of the mouth injuries heal without stitches. However, you should consult the doctor immediately in case of:\nNon-stop bleeding\nGaping wounds\nCuts through the border of the lip\nInjury to the back of the throat or palate\nWounds with severe pain and difficulty breathing or swallowing\nHow to handle mouth injuries at home?\nApply pressure on cuts using a clean cloth or gauze wet with cold water for up to 15 minutes.\nRinse your child’s mouth with warm water after meals to wash away foods to avoid foods from sticking on the cut.\nAvoid spicy, salty or citrus foods such as lime or oranges until the cut heals completely. Give your child bland foods during this time.", "pred_label": "__label__POS", "pred_score_pos": 0.9301189184188843}
{"content": "TOKYO, Oct 14, 2020 – (JCN Newswire) – Mitsubishi Heavy Industries, Ltd. (MHI) has made a financial investment in HydrogenPro AS of Norway, a company engaged in the development and manufacture of electrolyzers, devices that produce hydrogen by the process of water electrolysis. MHI subscribed to newly issued shares placed by HydrogenPro in an initial public offering (IPO) undertaken to fund expansion of its business operations. MHI already provides various decarbonization technologies that allow for a realistic path towards net-zero and will form the strategic partnership with HydrogenPro to further expand its portfolio and provide green hydrogen production plants to the market going forward.\nHydrogenPro was established in 2013 based in the Norwegian city of Porsgrunn, Telemark County. The history of water electrolysis technology traces back to 1927, when a fertilizer and heavy water plant employing water electrolysis technology was launched in Telemark by Norsk Hydro, a Norwegian state owned conglomerate. HydrogenPro has already developed a 9 megawatt (MW) class hydrogen production system (production capacity: 4.4 tons/day) adopting water electrolysis technology incorporating a pressurized cells with alkaline electrolyte. Plans are now underway toward achieving a 100 MW class plant (capacity: 48 tons/day).\nToday, demand is growing for green hydrogen production plants, especially in Europe. France has announced a target of 6.5 gigawatts (GW) in electrolyzer capacity by 2030, Germany is targeting a capacity of 5 GW by 2030, and 10 GW by 2040, while the EU aims at securing 40 GW of renewable hydrogen electrolyzers by 2030.\nMHI’s investment in HydrogenPro provides further financial stability and long-term certainty for projects utilizing green hydrogen to decarbonize various sectors. MHI’s investment in HydrogenPro not only signals its confidence in HydrogenPro’s offerings, but more importantly, this investment underscores its confidence in the green hydrogen market which will be supported by a multitude of electrolyzer manufacturers and technologies.\nGoing forward, MHI will continue to explore technology innovations that will drive decarbonization of industrial sectors including power generation, refinery, fertilizer, steel and transport utilizing hydrogen as fuel, feedstock, or for hydro processing. In parallel with initiatives promoting green hydrogen, MHI will explore the feasibility of hydrogen derived from fossil fuel in combination with CCUS (carbon capture, utilization and storage) – blue hydrogen – as another approach to decarbonize industries.\nAbout Mitsubishi Heavy Industries, Ltd.\nMitsubishi Heavy Industries (MHI) Group is one of the world’s leading industrial firms. For more than 130 years, we have channeled big thinking into solutions that move the world forward – advancing the lives of everyone who shares our planet. We deliver innovative and integrated solutions across a wide range of industries, covering land, sea, sky and even space. MHI Group employs 80,000 people across 400 locations, operating in three business domains: “Power Systems,” “Industry & Infrastructure,” “Aircraft, Defense & Space.” We have a consolidated revenue of around 40 billion U.S. Dollars. We aim to contribute to environmental sustainability while achieving global growth, using our leading-edge technologies. By bringing people and ideas together as one, we continue to pave the way to a future of shared success.\nFor more information, please visit MHI’s website: https://www.mhi.com\nFor Technology, Trends and Tangents, visit MHI’s new online media SPECTRA: https://spectra.mhi.com\nCopyright 2020 JCN Newswire. All rights reserved. www.jcnnewswire.com", "pred_label": "__label__POS", "pred_score_pos": 0.5068514347076416}
{"content": "Understanding the pathways from biodiversity to agro-ecological outcomes: A new, interactive approach\nChang, Mauricio G.; Wratten, Stephen D.; Shields, Morgan; Costanza, R.; Dainese, M.; Gurr, G. M.; Johnson, Janine; Karp, D. S.; Ketelaar, J. W.; Nboyine, Jerry; Pretty, J.; Rayl, Ryan; Sandhu, H.; Walker, M.; Zhou, W.\nAbstract\nThe adoption of agro-ecological practices in agricultural systems worldwide can contribute to increased food production without compromising future food security, especially under the current biodiversity loss and climate change scenarios. Despite the increase in publications on agro-ecological research and practices during the last 35 years, a weak link between that knowledge and changed farmer practices has led to few examples of agro-ecological protocols and effective delivery systems to agriculturalists. In an attempt to reduce this gap, we synthesised the main concepts related to biodiversity and its functions by creating a web-based interactive spiral (www.biodiversityfunction.com). This tool explains and describes a pathway for achieving agro-ecological outcomes, starting from the basic principle of biodiversity and its functions to enhanced biodiversity on farms. Within this pathway, 11 key steps are identified and sequentially presented on a web platform through which key players (farmers, farmer networks, policy makers, scientists and other stakeholders) can navigate and learn. Because in many areas of the world the necessary knowledge needed for achieving the adoption of particular agro-ecological techniques is not available, the spiral approach can provide the necessary conceptual steps needed for obtaining and understanding such knowledge by navigating through the interactive pathway. This novel approach aims to improve our understanding of the sequence from the concept of biodiversity to harnessing its power to improve prospects for ‘sustainable intensification’ of agricultural systems worldwide.... [Show full abstract]\nKeywordsagroecology; interactive tool; sustainable intensification; biodiversity; implementation pathway; outcomes; Agronomy & Agriculture Fields of Research070108 Sustainable Agricultural Development; 070301 Agro-ecosystem Function and Prediction; 070103 Agricultural Production Systems Simulation; 05 Environmental Sciences; 07 Agricultural and Veterinary Sciences; 16 Studies in Human Society Date2020-10-01 TypeJournal Article Collections MetadataExpand record\n© 2020 The Authors. Published by Elsevier B.V.", "pred_label": "__label__POS", "pred_score_pos": 0.6179671287536621}
{"content": "A prophet once said, “Your anger is a gift.”\nThat prophet was Zack De La Rocha.\nIn this age of incivility, many crave civility as an ends in itself.\nHowever, civility is a situational virtue. In many ways, civility is a bourgeois virtue. It protects the powerful and the comfortable, because uncivil behavior is a threat to them most of all.\nDo not agitate. Do not criticize. It is not civil and nice. Martin Luther King’s Letter for Birmingham Jail was a response to those that that agreed with his goals but who felt that he was causing too much trouble. Those who said “wait” then now say “be civil.”\nNow, some might say that this is hypocritical of me. Didn’t liberals like me criticize Glenn Beck for lacking civility? Well, some did. However, I never did. My issues with Bro. Beck were with the content of his views and message. Whether he was “civil” or not was irrelevant to me.\nDoes civility have a place? Absolutely! Civility within families, within organizations, and amongst neighbors is a wonderful thing. Likewise, incivility is not a virtue in and of itself. It is sometimes appropriate, but it often is not. Surely it can be annoying. In many ways, that is the point. It should be used strategically.\nNow, anger itself is not a virtue unless it is rooted in good ground. I would contend that we need more anger rooted in social justice. More specifically, we need anger rooted at injustice.\nAdditionally, we need to make a distinction between anger and hate. Loving our neighbor and enemy still applies. Injustice should anger us. We should not hate people. This requires a certain discipline which is rooted in moral firmness. This moral firmness can be rooted in a religious or secular philosophy. Roots are needed, but the nature of those roots are of minor concern to me.\nThe proper and the comfortable will surely disagree. They do not make me angry. However, I do laugh at their discomfort.\nCategories: Blog", "pred_label": "__label__POS", "pred_score_pos": 0.9443707466125488}
{"content": "\"A Few Months to Live\" describes what dying is like from the perspectives of nine terminally ill individuals and their caregivers. Documenting a unique study of end-of-life experiences that included detailed conversations in home care settings, the book focuses on how participants lived their daily lives, understood their illnesses, coped with symptoms - especially pain - and searched for meaning or spiritual growth in their final months of life. The accounts are presented largely in the participants' own words, illuminating both the medical and non-medical challenges that arose from the time each learned the \"bad news\" through their final days of life and memorial services. Describing the nationwide crisis that surrounds end-of-life care, the authors contend that informal caregiving by relatives and close friends is an enormous and too-often invisible resource that deserves close and public attention. By incorporating not only the ill person's but also the family's perspective, they portray the nine participants in the contexts of their daily lives and relationships rather than simply as patients. Addressing such issues as palliative care, quality of life, financial hardship, grief and loss, and communications with medical personnel, the authors identify how families, professionals, and communities can respond to the challenges of terminal illness and the need to confront life's end.", "pred_label": "__label__POS", "pred_score_pos": 0.9783220291137695}
{"content": "The Edo State Government has set aside 1000 hectares for cassava cultivation in the state, as part of its agriprenuer programme targeted at galvanising women farmers towards realising its food security target.\nIn a statement signed by the Permanent Secretary, Ministry of Agriculture and Natural Resources, Godwin Okonofua, the state government said the 1000 hectares of land are dedicated for cassava production under the women empowerment initiative.\nHe noted that the state sourced funds from the Central Bank of Nigeria under the auspices of the Commercial Agricultural Credit Scheme towards implementing the project.\n“The government has undertaken to clear 1,000 hectares at Oria, Esan South East Local Government Area for its women empowerment initiative,” he said.\nThe state government is pursuing a holistic agricultural programme that prioritises key crops, notably rice, maize, cassava and oil palm, with heavy public and private sectors’ involvement.\nWhile the state government is working with the Nigeria Incentive-Based Risk-Sharing System for Agricultural Lending (NIRSAL) for the projects on rice and maize, using mechanised farming, private companies are expanding their investments in oil palm plantations, with new entrants bolstering the agricultural scene in the state.\nIn a recent chat with journalists, Special Adviser to Governor Obaseki on Agriculture, Food Security and Forestry, Prince Joe Okojie, said the state government accessed N5bn from the CBN for its agricultural programme. Of the money, he said N2.2bn would be used for crop production, N2.3bn for land development and N100m for irrigation.\nHe explained that N1.2bn would be used to cultivate rice in Iguoriakhi, Iguomon, Illushi, Warrake and Agenebode while Maize would be cultivated at Usugbenu, Sobe and Ekpoma.", "pred_label": "__label__POS", "pred_score_pos": 0.630227267742157}
{"content": "(University of St Andrews and Getty Research Institute)\nIn the fifteenth century the Face of Christ found an enthusiastic devotee at the Burgundian court. Philip the Good (1396-1467) owned his grandfather’s immense prayerbook, known as the Grandes Heures. His grandfather, Philip the Bold (1342-1404), had used the manuscript heavily. All of the inherited signs of wear may have encouraged the younger Philip to treat it as a living, physical, functional manuscript rather than as some showpiece. As Anne van Buren has shown, Philip the Good had the book dismantled and had texts and images added to it before having it rebound in two volumes (Cambridge, Fitzwilliam Museum; and Brussels, Royal Library). Among the items he added to the book were at least 6 parchment sheets that each depicted the Face of Christ. Each of these has a different size, style and provenance. What’s clear is that 1) Philip the Good added these images successively over time, which reveals his sustained interest in this theme; and 2) he venerated them in a particularly physical way by handling them and touching their surfaces to the point where the images are severely darkened with use.\nThis paper has a twofold aim. First, I will contextualise Philip’s interest in this iconography by considering his other book commissions, including the large grisaille Prayerbook of Philip the Good (Hague, Royal Library). Secondly, I speculate on how and why he treated these images of the Face of Christi in such a physical manner. To do this, I will investigate Philip’s broader patterns of devotional performance and consider his behaviour against cultural norms of the fifteenth century. Grounding my study in the ideas of Marcel Mauss (‘Techniques of the body’), I aim to show how Philip set behavioural trends in the rugged handling of images of the Face of Christ.", "pred_label": "__label__POS", "pred_score_pos": 0.8425248861312866}
{"content": "The evaluation and disclosure of environmental liabilities is a key responsibility of environmental attorneys and environmental managers (EM). The financial reporting requirements of the Securities and Exchange Commission (SEC) associated with annual reports or financial statements for governmental and public companies help drive this effort. While private companies are not required to report publicly, they need to have regular reporting for their banking institutions and financial stockholders. This process has no real standardized framework, but the Financial Accounting Standards Board (FASB), the Governmental Accounting Standards Board (GASB), ASTM International, the SEC, and many other sources offer guidance documents to support this work.\nPremium Content For: Environment, Energy, and Resources Section", "pred_label": "__label__POS", "pred_score_pos": 0.6618107557296753}
{"content": "Unterm Strich. Erbschaften und Erblasten für das Deutschland von morgen.\nGermany is facing great societal changes. In many regions, Germany's population is shrinking and work forces are decreasing. Demographic change is challenging Germany, leading to economic and social shifts and creating new social divisions in many regions and cities. While a growing population has long been understood as a threat to the environment, it is now clear that a shrinking population does not automatically improve the environmental situation. \"The Bottom Line\", edited by Volker Hauff and Günther Bachmann, with contributions from Ecologic and the Berlin-Institute, examines the assets and debts of Germany's future inheritance.\nAcross a variety of public policy issues, from public transport to waste water treatement, ecological benefits as well as their financing are being questioned. However, the situation also provides opportunities. By raising the stakes around key societal issues, the demographic shift means there is a growing public interest in finding effective solutions to old problems Political and social shortcomings are now clearer and the need to solve them more urgent. This is yielding new support for policy measures such as easing the financial burdens of families, restricting settlement boundaries, fostering early childhood education, and actively steering immigration. As an intergenerational appraisal, \"The Bottom Line\" distinguishes future options from future burdens and sheds new light on the chances, problems and challenges raised by settlement patterns, labor markets, education, immigration, nature conservation, energy use and transportation.\nThe book is available for download.", "pred_label": "__label__POS", "pred_score_pos": 0.876178503036499}
{"content": "Executive Intelligence\nYour high-profile employees represent the company’s brand to shareholders, media, clients, and personnel. They also enjoy access to your company’s most sensitive financial records, personnel data, and plans for the future. With such high visibility, thorough background screening of your senior personnel is of paramount importance.\nExecutiveOps Intelligence is designed especially for organizations that require a more extensive background check on certain individuals slated for high-profile or high-risk positions. A specialized research analyst compiles detailed information, delivering a comprehensive overview of key elements of a candidate’s professional and personal history in an easy-to-understand report.\nXO's Executive Intelligence product will help fulfill your hiring needs with these benefits:\nHelping you hire the right high-profile candidates Reducing risk in your potential high-profile hires Protecting your brand and reputation\nExecutive hiring is a challenge because, unlike regular employees, executive job candidates have unique professional histories and expectations of a white-gloved approach to the hiring process. An executive candidate will also have a more significant ability to influence change at your organization than the average employee; necessitating a more thorough background check.", "pred_label": "__label__POS", "pred_score_pos": 0.8862996101379395}
{"content": "Why do I need a personal injury attorney?\nIf you are injured in an accident, you may be quickly presented with a settlement offer from the responsible party’s insurance company, or even from your own insurance company. When you are offered compensation with no effort on your part, you may wonder why you need to hire a personal injury attorney. The fact is that such quick offers for a personal injury settlement are often totally inadequate to cover the expenses and damages you have incurred and will continue to incur long after you accept a check.\nWhen you hire a personal injury attorney to represent you, your lawyer will advocate on your behalf to push the insurance companies to offer you a settlement that fully compensates you for all your past and future medical expenses, lost wages and earning capacity, and pain and suffering. If the insurance companies are not willing to fully compensate you, an attorney can file and pursue a personal injury lawsuit on your behalf.", "pred_label": "__label__POS", "pred_score_pos": 0.7635658979415894}
{"content": "The Centers for Disease Control and Prevention has issued a temporary eviction ban to help prevent further spread of the coronavirus.\nThe ban, which ends Dec. 31, covers people who become ill or who are at risk for severe illness from the novel coronavirus due to an underlying medical condition.\nThe CDC’s order does not apply in any state, local territorial or tribal area “with a moratorium on residential evictions that provide the same or greater level of public-health protection than the requirements listed.”\nHowever, while the ban may halt evictions prompted by mass layoffs due to the coronavirus, the order could also negatively affect landlords who will not be able to collect unpaid rent.", "pred_label": "__label__POS", "pred_score_pos": 0.883755087852478}
{"content": "Hello. Honestly, it wouldn't matter if this were a hobby or an extracurricular activity. It is well documented with the court and the committee meeting minutes that the tables used to derive the parental child support obligations are inclusive of every conceivable expense for a family. When a parent is \"residential\" or \"custodial\" they receive all the money for all these expenses and they are expected to pay for them using child support money.\nIt is a common misconception that a child should be able to be supported on child support. This narrative is completely false. Kansas is an income shares state which puts a financial obligation on each parent to pay their respective share of the expenses. So the child support payment only represents the father's portion. Mother also needs to contribute. My personal opinion is that cheer is absolutely an extracurricular activity. Terming it a \"hobby\" is tomato/tomoto. Cheerleading is practiced in schools. Just because you decide to spend $1k or more per month for competitive cheer doesn't make it a hobby. But, to my previous point - it doesn't matter what you call it. While I sat on the advisory committee I was in the room when a similar question was asked of the state economist. It was concluded that families who elect to spend enormous amounts on frivolous activities simply take away from other activities (and potentially needs). This would be the case with married families - there's no reason to provide additional advantages to children of separated families. If it can't be afforded in a married family, it can't be afforded by a separated family. A little blunt, but that's my opinion.", "pred_label": "__label__POS", "pred_score_pos": 0.7790435552597046}
{"content": "Now in its 20th year, the survey is an annual assessment of the current and future state of the global automotive industry.\nThe\n2019 Global Automotive Executive Survey marks the 20th year that KPMG has interviewed approximately 1000 automotive executives and 2000 consumers worldwide, to understand how the global automotive sector is growing, changing and reacting to challenges and opportunities. Key findings:\nFor further details, visit the interactive platform for KPMG’s Global Automotive Executive Survey at\nhome.kpmg/gaes2019 and compare statistics by country, region, questions asked and more.\nFor a summary of the global results,\ndownload the PDF here.", "pred_label": "__label__POS", "pred_score_pos": 0.9521902799606323}
{"content": "Cyclic nucleotide-gated (CNG) channels are crucial for visual and olfactory transductions. These channels are tetramers and in their native forms are composed of A and B subunits, with a stoichiometry thought to be 2A:2B (refs 6, 7). Here we report the identification of a leucine-zipper-homology domain named CLZ (for carboxy-terminal leucine zipper). This domain is present in the distal C terminus of CNG channel A subunits but is absent from B subunits, and mediates an inter-subunit interaction. With cross-linking, non-denaturing gel electrophoresis and analytical centrifugation, this CLZ domain was found to mediate a trimeric interaction. In addition, a mutant cone CNG channel A subunit with its CLZ domain replaced by a generic trimeric leucine zipper produced channels that behaved much like the wild type, but less so if replaced by a dimeric or tetrameric leucine zipper. This A-subunit-only, trimeric interaction suggests that heteromeric CNG channels actually adopt a 3A:1B stoichiometry. Biochemical analysis of the purified bovine rod CNG channel confirmed this conclusion. This revised stoichiometry provides a new foundation for understanding the structure and function of the CNG channel family.", "pred_label": "__label__POS", "pred_score_pos": 0.8456701636314392}
{"content": "This study examined perceived risk of harm from smoking or ST use in a U.S. nationally representative sample of high school seniors and examined its association with current smoking status. Data were derived from the Monitoring the Future project for 1999 through 2003 (n = 11,093). We used multiple logistic regression analysis to examine the association between comparative perceived risk of harm of smoking and ST use with current smoking status, while adjusting for sex, race, and perceived risk of harm from smoking. In 1999-2003, 74.0% of high school seniors perceived great risk of harm from smoking and 44.9% perceived great risk from using ST. Perceived risk varied by smoking intensity: 80.3% of non-smokers perceived great risk of harm from smoking, compared to 49.7% of students who smoked about one-half pack per day and 36.1% of pack-a-day smokers. Overall, 52.7% perceived equal risk of harm from using either product, 41.3% perceived greater risk from cigarettes, and 6.1% perceived a greater risk from using ST. Adjusting for sex and race, high school seniors who perceived that smoking conveyed a greater risk for harm than did using smokeless tobacco were significantly more likely to be smokers than were those who perceived equal risk from the products (odds ratio [OR] = 1.43; 95% confidence interval [CI] 1.29-1.60). Those who perceived that using smokeless tobacco was riskier than smoking were even more likely to be current smokers (OR = 2.43; 95% CI 1.96-3.01). Effective methods for communicating accurate health risks to young people are needed.", "pred_label": "__label__POS", "pred_score_pos": 0.5207594633102417}
{"content": "Progressive myoclonus epilepsies (PMEs) are a group of rare, inherited disorders manifesting with action myoclonus, tonic-clonic seizures and ataxia. We sequenced the exomes of 84 unrelated individuals with PME of unknown cause and molecularly solved 26 cases (31%). Remarkably, a recurrent de novo mutation, c.959G>A (p.Arg320His), in KCNC1 was identified as a new major cause for PME. Eleven unrelated exome-sequenced (13%) and two affected individuals in a secondary cohort (7%) had this mutation. KCNC1 encodes KV3.1, a subunit of the KV3 voltage-gated potassium ion channels, which are major determinants of high-frequency neuronal firing. Functional analysis of the Arg320His mutant channel showed a dominant-negative loss-of-function effect. Ten cases had pathogenic mutations in known PME-associated genes (NEU1, NHLRC1, AFG3L2, EPM2A, CLN6 and SERPINI1). Identification of mutations in PRNP, SACS and TBC1D24 expand their phenotypic spectra to PME. These findings provide insights into the molecular genetic basis of PME and show the role of de novo mutations in this disease entity.", "pred_label": "__label__POS", "pred_score_pos": 0.6749060153961182}
{"content": "Abstract\nOsteoporosis is a major public health concern. The combination of exercise, hormone replacement therapy, and calcium supplementation may have added benefits for improving bone mineral density compared to a single intervention. To test this notion, 320 healthy, non-smoking postmenopausal women, who did or did not use hormone replacement therapy (HRT), were randomized within groups to exercise or no exercise and followed for 12 months. All women received 800 mg calcium citrate supplements daily. Women who exercised performed supervised aerobic, weight-bearing and weight-lifting exercise, three times per week in community-based exercise facilities. Regional bone mineral density (BMD) was assessed by dual energy X-ray absorptiometry. Women who used HRT, calcium, and exercised increased femoral neck, trochanteric and lumbar spine bone mineral density by approximately 1-2%. Trochanteric BMD was also significantly increased by ∼1.0% in women who exercised and used calcium without HRT compared to a negligible change in women who used HRT and did not exercise. The results demonstrate that regional BMD can be improved with aerobic, weight-bearing activity combined with weight lifting at clinically relevant sites in postmenopausal women. The response was significant at more sites in women who used HRT, suggesting a greater benefit with hormone replacement and exercise compared to HRT alone.\nKeywords Bone mineral density Exercise Hormone replacement Osteoporosis Postmenopausal Women", "pred_label": "__label__POS", "pred_score_pos": 0.831866443157196}
{"content": "Can grandparents pursue visitation rights?\nGrandparents have unique bonds with their grandchildren. You may have played an influential role in the upbringing of your grandchild, helping them with their homework, spending weekends and holidays together and more.\nHowever, whether due to divorce or a family rift, your time with your grandchild may seem uncertain. California allows grandparents to seek visitation rights for their grandchildren. Yet, the process to do so can be complicated and depend upon your family’s situation. Do you have options to remain in your grandchild’s life?\nPursuing “reasonable visitation”\nWhen your time with your grandchild is at risk, first attempt to resolve the dispute outside of the courtroom. Resolving family disputes amicably can preserve relationships and ultimately benefit the child by avoiding a potentially costly and bitter legal battle.\nIn some cases, such attempts may prove to be unsuccessful. Grandparents may then pursue reasonable visitation rights under California law. In determining whether to award these rights, courts must first establish a pre-existing relationship between you and the grandchild. This means proving that your relationship has formed a bond that would make visitation rights in the best interests of the child.\nThen, the court must weigh potential grandparents’ visitation rights with the rights of the child’s parents. Courts ultimately act in the best interests of the child, which often includes preserving and encouraging the child’s relationship with both parents. The court will attempt to balance these relationships when it benefits the child.\nExceptions to seeking visitation rights\nOne barrier to seeking reasonable visitation is the marriage of the child’s parents. When the child’s parents are married, you may have limited options to successfully seek visitation rights. However, there are exceptions, such as:\nIf the parents live separately If the child does not currently live with either parent If the location of one parent has been unknown for at least one month If a stepparent has adopted the child If one parent has joined the grandparent’s petition for visitation rights\nThese exceptions can also apply after the court grants visitation rights. For example, if the parents who previously lived apart move back in together, the parents may petition the court to revoke the visitation rights.\nThe prospect of losing valuable time with your grandchild can be devastating. As pursuing grandparents’ visitation rights can be complex, consider discussing your situation with an attorney to learn your options and pursue your rights.", "pred_label": "__label__POS", "pred_score_pos": 0.9979707598686218}
{"content": "Although throwing injuries in the shoulder most commonly occur in baseball pitchers, they can be seen in any athlete who participates in sports that require repetitive overhand motions, such as volleyball, tennis, and some track and field events.\nSymptoms of a SLAP tear may include:\nPopping, clicking, or catching in the shoulder.\nPain when you move your arm over your head or throw a ball.\nA feeling of weakness or instability in the shoulder.\nAching pain. People often have a hard time describing or pointing to exactly where the pain is.", "pred_label": "__label__POS", "pred_score_pos": 0.6178561449050903}
{"content": "A Digital Bar Crawl\nUpdated: May 21\nOld Monk, the iconic Indian rum has been enjoyed by tens of millions of Indian men (and several women). My dad, a scotch drinker, would go back to Old Monk on special occasions. A bartender (mixologist, as she corrected me) at a Chelsea bar (of the London variety) surprised me with a choice of half a dozen cocktails based on Old Monk!\nWhile by no means a new art, mixology is enjoying a global revival, with searches for craft cocktails across the world rising fivefold between 2010 and 2018. No longer a forbidden pleasure or insurance against disease, today’s cocktails answer the millennial consumer’s call for intentional food experiences, joining the ranks of artisanal coffee, cooking, beer, and a growing list of food industries.\nUnique even among these, mixology takes hipster food culture’s respect for origin and creative vision, adding a theatrical flair that other sectors have only just started to mimic. In a professional’s hands modern bartending is choreography, with regional styles ranging from New York’s colorful speakeasies to Tokyo’s subtle, precise approach. Its breadth of techniques is surpassed only by its willingness to play with bold ingredients, as elite bartenders stretch customer tastes while remaining relevant in a crowded marketplace.\nThe industry has come a long way with from dried octopus to edible soil. I wondered about the trends tying these concoctions together. Could I, a cocktail enthusiast figure out where the industry is headed without years of barbacking or bankrupting myself at the bars?\nA DIGITAL BAR CRAWL\nCurious, I gathered signature drinks from the top 20 bars in Perrier’s list of the best in the world, whose bartenders are recognized as trailblazers and trendsetters in the industry. My colleagues and I ran 182 recipes through an AI NLP engine, weighing keywords for popularity across different drink and alcohol types. We correlated these to search trends throughout 2018 around five common base spirits — gin, whiskey, rum, vodka, and tequila/mezcal — in Singapore, London, and New York.\nWe found that gin is currently the most popular spirit worldwide, appearing in 25% of consumer search interest and 31% of signature drinks. Whiskey comes in a close second, taking up 21% of search and 25% of signature drink interest. Curiously, although vodka represents 23% of consumer searches, it is far less popular among elite bartenders (12%), who prefer rum (19%) in their drink selection.\nAcross all drink categories, citrus (46%) is by far the most common flavor note, reflecting a well-established market preference for acidity shown in the growing popularity of light-roasted African coffees, sourdough breads, and the rise of sours in craft beer. To balance this, craft bartenders use infused liqueurs (29%) and bitters (20%) to add complexity, weaving in sweetness (19%) as a note instead of placing it front and center. Broadly speaking, tropical flavors such as passionfruit and pineapple were trendy (11%), with warmer notes such as spices, woodiness, and chocolate closely trailing (7%).\nRegionally, several interesting insights surfaced:\nPopularised in London as the drink of the disreputable, gin enjoys five times as much interest in the city as its nearest competitor, whiskey. Local brand Beefeater enjoys a twofold or threefold lead, with Scottish brands Hendricks and Tanqueray dominant in New York and Singapore.\nRum and tequila are largely still seen as lowbrow or party drinks, with searches across all three cities reflecting little awareness of craft consumption. Consumer interest focused on generic recipes and mainstream brands such as Captain Morgan, Kraken, Bacardi, Jose Cuervo, and Patrón.\nNew York drinkers were familiar with niche brands such as Brugal (Dominican Republic) and Zapaca (Guatemala) rum, as well as less common subcategories such as sotol (an aged agave liquor). They were more likely to seek origin and production information in tequila, suggesting that they are more open-minded and exploratory as drinkers\nThe whiskey market is highly differentiated across regions. Where London whiskey drinkers focus on Scottish and Irish single malts, Singaporean drinkers take to established, high-end craft brands from Japan, Scotland, and the United States. New York drinkers span the gamut, enjoying foreign single malts and budget bourbons alike\nTHE NEXT HIP ALCOHOL\nAnalysing search behavior and trendsetters in tandem enables one to get a feel for popular trends, catching shifts in taste before they lose their novelty. At any point, only one or two base spirits dominate consumer preferences in each market. Even among elite bartenders, a group known for its willingness to experiment, these main spirits account for up to 50% of signature drinks.\nAlthough this is currently gin’s moment of fame, we believe that dark rum will be the next meaningful trend in mixology. Sweet and complex, with warm tropical notes, dark rum offers a strong base for the flavor notes elite bartenders are leading the market towards.\nIf you enjoyed reading this post, you might also like:", "pred_label": "__label__POS", "pred_score_pos": 0.5402604341506958}
{"content": "By Ragan M Conteh\nThe National Revenue Authority (NRA) will next year continue its tax education program, including targeted taxpayer workshops, publishing relevant taxpayer education materials, production and airing of jingles, use of celebrities and activists for tax education and implementing a National Taxpayers Awards Day by the end of the year.\nAccording to the 2021 budget, the National Revenue Authority will implement a Domestic Tax Preparers Scheme that would allow trained tax agents to help small and medium taxpayers in record keeping and tax compliance.\nTo prevent under-declaration and smuggling, at customs, the NRA will activate the valuation module of the ASYCUDA World System and enhanced it with an international price reference database, while fully utilising the newly constructed cargo inspection facility at the seaport.\nThe authority will operationalize excise stamp duty on imports of alcohol, tobacco and other commodities subject to excise duties, thereby controlling smuggling associated with the importation of these commodities.\nThe 2021 budget has several tax policy measures, which have been proposed in the 2021 Finance Bill to protect local manufacturing industries, enhance the efficiency and effectiveness of tax administration, cushioning the lingering effect of COVID-19 on businesses, especially SMEs, improve consumer welfare, and support Government priority areas, among others.\nIn the area of duty and tax exemptions, the duty and tax waivers constitute a significant source of revenue loss due to the continued abuse and misuse of the facility by some beneficiary agencies. Despite the drop, from Le601.0 billion, in 2019, to Le326.0 billion, during the first three quarters of 2020, duty and tax waivers still remain high. The share of duty and taxes waived, on donor funded projects, is also high at 22%.", "pred_label": "__label__POS", "pred_score_pos": 0.5491727590560913}
{"content": "Our client, ‘Mary’, suffered a lower back injury, and had been medically unfit for work for 12 weeks. She was reporting high levels of pain and poor function despite attending physiotherapy and receiving adequate medical management. Mary believed her pain would become much worse if she attempted to return to work.\nPrior to her injury, Mary reported she experienced a multitude of workplace internal issues, including a poor relationship with her employer, a high workload and a risk of redundancy.\nShe presented as depressed and struggling with the day to day demands of everyday life – demonstrating minimal motivation to increase her hours of work in line with medical guidelines. Mary’s treating doctor and physiotherapist were also very passive, resulting in capacity upgrades being difficult to negotiate.\nMary was referred to PeopleSense by Altius psychologists to participate in the Enhanced Recovery Program (ERP).\nAfter just a few sessions of the Enhanced Recovery Program, Mary demonstrated a complete shift in her mindset, indicating an eagerness to increase her working hours. This led to Mary independently visiting her treating doctor to negotiate a full medical clearance for work, up to one month ahead of schedule.\nMary confirmed that the rapport she developed with her psychologist during the ERP, and the strategies provided to her during the program were the prominent factors for this turn around, and her return to work success.\nThis is a familiar story we observe at Altius Group with injured workers - regardless of age, industry or education. A poor understanding of pain, a tendency to avoid activity along with reports of previous workplace conflict are strong factors that influence a clients’ motivation to return to work after injury.\nPsychosocial risk factors such as these can complicate recovery from a physical injury and, if not addressed in the early stages, can often lead to a poor return to work outcome.", "pred_label": "__label__POS", "pred_score_pos": 0.9956774711608887}
{"content": "The solvation and the onset of dissolution of a cellulose I beta microcrystal in ionic liquid media are studied by molecular simulation. Ionic liquids can dissolve large amounts of cellulose, which can later be regenerated from solution, but their high viscosity is an inconvenience. Hydrogen bonding between the anion of the ionic liquid and cellulose is the main aspect determining dissolution. Here we try to elucidate the role of a molecular cosolvent, dimethyl sulfoxide (DMSO), which is an aprotic polar compound, in the system composed of cellulose and the ionic liquid 1-butyl-3-methylimidazolium acetate. We calculated quantities related to specific interactions (mainly hydrogen bonds), conformations, and the structure of local solvation environments, both for a solvated oligomer chain of cellulose and for a model microfibril composed of 36 chains in the 1b crystal structure. We compare two solvent systems: the pure ionic liquid and a mixed solvent with an equimolar composition in ionic liquid and DMSO. All entities are represented by detailed all-atom, fully flexible force fields. The main conclusions are that DMSO behaves as an \"innocent\" cosolvent, lowering the viscosity and accelerating mass transport in the system, but without interacting specifically with cellulose or disrupting the interactions between cellulose with the anions of the ionic liquid. An understanding of solvation in mixed solvents composed of ionic liquids and molecular compounds can enable the design of high-performance media for the use of biomass materials.", "pred_label": "__label__POS", "pred_score_pos": 0.7658010721206665}
{"content": "On May the 5th, Baker Hughes Incorporated (NYSE: BHI) released their monthly international rig count numbers. The firm confirmed that the number of international rigs during April of 2017 was up 13 to 956. March of 2017 had 943, while April of 2016 had 946 international rigs. The average rig count in the United States for the month of April was 853 equating to an increase of 64 rigs compared to March. The Canadian rig count was down by 145 from March 2017 to April 2017. The average Canadian rig count topped out at 108, while the figure rested at 253 in March of the same year.\nOverall, the worldwide rig count took a small dip dropping from 1,985 in March to 1,917 in April of 2017. April’s worldwide rig count was significantly higher than the same month the previous year, with an increase of 493 rigs year over year. Nevertheless, oil prices now trade at a 5-month low after taking a massive slide on Thursday. The drops come despite reassurances from Saudi Arabia that Russia was on the verge of joining OPEC in extending cuts. Saudi Arabia’s OPEC Governor Adeeb Al-Aama recently told Reuters that OPEC and non-OPEC countries were very close to striking a new deal regarding supply cuts. Despite the news, a Kremlin spokesperson admitted a decision had not yet been made regarding Russia’s involvement in the cuts.\nIt is believed that OPEC will agree to extend cuts when the group meets on May 25. However, a more significant cut is unlikely. Previously, OPEC and non-OPEC countries agreed to cut production by 1.8 million barrels a day for the first 6 months of the year. Despite the previous and impending cuts, climbing oil output from the United States weighs heavily on traders. Slow Chinese demand has also helped to drag down oil prices. At the time of this writing, crude oil prices sit close to the 45.50 mark.", "pred_label": "__label__POS", "pred_score_pos": 0.9736876487731934}
{"content": "Dr. Jay explains that inactive ingredients in pesticides can be even more toxic than the active ingredients. Dr. Todd adds that pesticides can worsen the effects of other toxins in your body and deplete nutrients.\nDr. Jay Davidson and Dr. Todd Watts begin each LIVE session by discussing a topic or challenge you may encounter on your path to optimal health. They share new insights and their clinical experience treating people with conditions like yours. Plus, you can ask the docs questions related to Microbe Formulas’ products during the session.\nAdd to Calendar12/2/2020 1:00 PM12/2/2020 2:00 PMAmerica/BoiseLive with the DocsWeekly live Zoom broadcast with Dr. Jay Davidson and Dr. Todd Wattshttps://microbeformulas.zoom.us/j/891188468Microbe Formulassupport@microbeformulas.com15FREQ=WEEKLY;BYDAY=WE;INTERVAL=1", "pred_label": "__label__POS", "pred_score_pos": 0.9601686000823975}
{"content": "Thirty-nine urbanized ethnic Namibian people comprising 21 Bushmen (semi-urbanized), 7 Hereros and 11 Kavangos were assessed for plasma lipids and fatty acid (FA) composition. Total cholesterol and triacylglycerol concentrations were measured by enzymatic methods, and neutral lipid FA composition by gas-liquid chromatography. The results demonstrated that while total cholesterol concentrations were not significantly different, significant differences in triacylglycerol concentrations (P < 0.05) were seen between Bushmen and Kavangos. By comparing Bushmen with Hereros and Kavangos, significant differences between Bushmen and Kavangos were also observed in plasma triacylglycerol FA compositions, particularly 16:0 (32.73% vs. 25.05%), 16:1n-7 (7.00% vs. 5.06%), 18:2n-6 (9.30% vs. 22.25%) and 20:3n-6 (0.12% vs. 0.48%), while Kavangos had higher 20:4n-6 levels than Hereros (1.44% vs. 2.00%). In plasma cholesteryl esters, Bushmen were significantly different from Kavangos in 16:1n-7 (8.85% vs. 4.93%), 18:1n-9 (32.06% vs. 23.07%) and 20:4n-6 (6.91% vs. 10.00%). Significant differences were also observed between Bushmen and Hereros in 18:0 (1.08% vs. 1.29%) and 18:2n-6 (35.68% vs. 45.50%). The FA of Namibian groups were also compared with South African reference groups comprising urbanized whites and Xhosas and rural Vendas. The differences in blood lipid values can be explained primarily by excessive alcohol consumption. These results suggest that semi-urbanized Bushmen have changed their diets under urbanized conditions which may increase their risk of coronary heart disease.", "pred_label": "__label__POS", "pred_score_pos": 0.9733179807662964}
{"content": "The blood meal of hard ticks such as Ixodes ricinus lasts several days. This is made possible by tick salivary factors that inhibit inflammation, haemostasis and the host immune response. We assessed the latter on a model of immune response in vivo. A significant reduction of specific IgM and IgG levels was observed in BALB/c mice infested 5 days before injection with bovine serum albumin (BSA) and QuilA but not in mice infested 5 days after the immunization. This effect was not observed in mock-infested mice and could not be attributed to the use of anesthetics. The antibody response was not merely delayed and the Th(1)/Th(2) balance appeared not altered. T-dependent zones and germinal centers in lymph nodes draining the tick bite site showed no apparent morphological alterations or shift in T cell subpopulations. However, the spleens of tick-infested mice had also an enlarged red pulp, indicating an increased extramedullary haematopoietic activity.", "pred_label": "__label__POS", "pred_score_pos": 0.9433315396308899}
{"content": "Pay Equity Glossary\nTrusaic is committed to helping employers achieve pay equity, every step of the way. We combine advanced data and statistical analyses with regulatory expertise to help companies strategize and reach their goals. We also provide education, resources, and the tools you need to navigate the complexities of pay equity. Below you’ll find an essential list of pay equity terms.\nLegitimate Business Factors (LBF): Legitimate Business Factors (LBF) are factors affecting compensation, including a seniority system, a merit system, a system which measures earnings by quality or quantity or production, and/or otherwise reflecting differences in skill, effort, responsibility, productivity, training, and working conditions.\nIdentified Factors (IF): Identified Factors (IF) are Legitimate Business Factors (LBF) that are present in a client’s data for a pay equity analysis.\nEmployee Classes: Employee classes refer to employees divided into groups by protected classes, e.g., gender and/or race/ethnicity.\nReference Class: A reference class is an employee group defined by a specific protected class to which other classes are compared, and is used for evaluating wage differences.\nAssessed Class: An assessed class is an employee class analyzed for a wage disparity relative to a reference class.\nSimilarly Situated Employee Group (SSEG): This refers to a collection of employees in which wages are expected to vary only due to Identified Factors (IF); two employees in the same SSEG with identical IF are expected to receive the same compensation.\nPay Analysis Group (PAG): A Pay Analysis Group (PAG) is a collection of Similarly Situated Employee Groups (SSEG) at different compensation levels; after adjusting for level compensation differences between two SSEGs, employees in those SSEGs with the same IF are expected to receive the same compensation.\nBase Wage Rate: Base Wage Rate refers to employer-defined regular compensation expressed as an hourly rate, excluding paid overtime and bonuses.\nTotal Compensation: Total compensation reflects total monetary compensation (including paid overtime and bonuses) divided by total hours, adjusted for overtime hours for non-exempt employees.\nRegression Analysis: This is an advanced form of statistical analysis in which weighted estimates are applied to different Identified Factors (IF) for determining wages; this type of analysis also measures pay disparities when applied to a Pay Analysis Group (PAG).\nPay Gap: A pay gap refers to an average compensation difference between an assessed class and the reference class without controlling for Identified Factor (IF) differences.\nPay Disparities: Pay disparities are average compensation differences between an assessed class and the reference class for which Identified Factor (IF) differences are controlled.\nCohort Analysis: This type of analysis compares average wages between assessed and reference class employees who match in terms of a particular Identified Factor (IF) or factors, e.g., sales workers who have overtime non-exempt status.\nWage Distribution: Wage distribution refers to effective hourly compensation ordered from low to high for a given protected class; it graphically compares low/middle/high wages within an assessed class with low/middle/high wages in the reference class.\nQuantile Comparison: A quantile comparison compares the proportions of assessed and reference class wage distributions that are below a specific wage. For example, what proportion of the wages for an assessed class are below the median (50%) wage of the reference class? If the proportions of an assessed class below specified wage points are consistently larger than those for the reference class, that may be additional evidence of a pay disparity.\nEconomic Significance: A context-dependent percentage difference in compensation that is large enough to review, consider, or address is considered to be economically significant.\nStatistical Significance: Statistical significance indicates the importance of a pay disparity as measured by the size of a test statistic.\nImpacted Class: An impacted class is an assessed class with an economically significant pay disparity.\nExposure: Exposure refers to total annual compensation differences for employees in impacted classes.\nPay Equity Audit (PEA): A Pay Equity Audit (PEA) is an audit conducted to assess whether an employer’s workforce is equitably compensated regardless of gender, race, ethnicity, or other factors, accounting for Identified Factors (IF).\nPay Gap Risk Assessment (PGRA): A Pay Gap Risk Assessment (PGRA) is an assessment of compensation differences between an assessed class and the reference class without controlling for Identified Factor (IF) differences; it is often used by employers as a tool to determine the need for a Pay Equity Audit (PEA).", "pred_label": "__label__POS", "pred_score_pos": 0.5470905303955078}
{"content": "According to media reports, at least ten incidents of birds striking different aircraft during landing or take-off have been reported in July. This is an alarming situation as birds striking aircraft can cause significant damage and in rare instances even cause a plane to crash.\nThe Civil Aviation Authority needs to take immediate notice and adopt a strategy to prevent aircraft from suffering further bird hits in future. The primary reason for birds entering a danger zone, which is runways, are the housing schemes that have been allowed in close proximity to airports. The open garbage bins or large heaps of trash scattered around these societies attract the feathered scavengers who inadvertently cross the path of airliners. The CAA must conduct a survey of all societies located close to runways and ask them to either remove the garbage bins altogether or ensure a quick disposal of trash to get rid of the birds.\nEngr. Riaz Akbar Wah Cantt", "pred_label": "__label__POS", "pred_score_pos": 0.9396529793739319}
{"content": "COVID-19 Resources\nAs a critical partner to your business, CSi Advisory Services understands the importance of our ability to continue to support our clients and their employees amidst this global health event.\nThe health and well-being of our associates, clients, and their employees is of utmost importance to us. We have been monitoring Coronavirus (COVID-19) developments closely through local authorities, the U.S. Centers for Disease Control and Prevention, and the World Health Organization. As the situation continues to evolve, we are keenly focused on our preparedness efforts to maintain a safe work environment for our associates and to sustain our business operations.\nVirtual or Phone Meetings\nCSi Advisory Services remains committed to providing support to our employers and their plan participants. While our in-person meetings are temporarily suspended, we are still very willing to conduct meetings over the phone or through video conferencing. If you would like us to host a group meeting for your employees or if your employees would like to schedule an individual meeting, please feel free to reach out to us using our Request for Consultation.\nCOVID-19 INSIGHTS FOR RETIREMENT PLAN SPONSORS\nAs of March 2020, the COVID-19 pandemic has made its impact throughout the United States. Not only has it had a significant effect to the economy, it has changed nearly every Americans way of life. It has most definitely made its mark on your company, which may present serious financial difficulties for your employees. Given the immediate financial impact that many individuals are facing, employers and retirement plan administrators should expect to receive inquiries from plan participants regarding access to retirement savings.\nSome companies may need to take action in regards to employer contributions and even personnel in the coming days, weeks and months. The following information is aimed at preparing you for inquiries, administration and decisions you might encounter, including:\nC.A.R.E.S. Act Legislation\nHardship Distributions\nLoans\nImpact of Furloughs\nPartial Plan Terminations\nPlan Investments\nEmployee Compensation\nEmployer Contributions\nC.A.R.E.S. Act Legislation\nThe Coronavirus, Aid, Relief, and Economic Security (C.A.R.E.S.) Act (the “Act”) was passed on March 27, 2020. The Act is intended to loosen access to retirement plan funds for individuals impacted by the COVID-19 pandemic. At present the following are elements of the Act:\nWaiver of 10% penalty on early withdrawals for amounts up to $100,000 from a retirement plan or IRA\nFor an individual who:\nIs diagnosed with COVID-19;\nWhose spouse is diagnosed with COVID-19;\nWho experiences adverse financial consequences due to furlough, quarantine, layoff, reduction in hours, inability to work due to lack of child care due to COVID-19, or closing of business/reduction of hours by individual due to COVID-19; or\nFactors determined by the Secretary of the Treasury\nIndividuals are allowed pay the tax on distributions ratably over a three year period; and\nIndividuals are allowed to repay the distribution back to the plan, tax-free, over the next three years (not limited by plan limits)\nPlan loan are impacted as follows:\nAmount available is doubled to the lesser of:\n$100,000; or\n100% of their vested account balance.\nIndividuals with outstanding loans with a repayment due from the date of enactment of CARES through December 31, 2020 may delay loan repayments for up to one year.\nRequired Minimum Distributions (RMD):\nTemporary suspension of the annual RMDs due in 2020\nParticipants who want to continue taking their distributions will be able to do so.\nThe plan will eventually need to be amended.\nAs legislation is quickly evolving, we will keep you informed of any and all pertinent information.", "pred_label": "__label__POS", "pred_score_pos": 0.6957228183746338}
{"content": "Hog Day 2019 Number Two Piggeries Group and Lionel’s Veterinary Supplies held their 15th annual Hog Day from 23 - 25 October 2019.\nThe theme was “Production to Profit” and concentrated on the cost of production and not solely on production and performance. Seven international speakers presented various topics and delegates were privileged to share their wealth of knowledge and experience.\nThe common “thread” among producers worldwide was that challenges are more frequent and greater; Survival and growth will be based on the following basics:\nIt must be about the people: look after your employees well, train them and motivate them.\nUse modern technology as often as possible – you are a global player.\nProtect your environment: it is the only one you have.\nAdopt animal welfare policies wherever possible.\nFocus on the big drivers in your business and be precise in planning, implementing and monitoring.\nTalent is never enough: you need to apply talent and you need to keep growing it.\nTeamwork and communication is key.\nLeave a LEGACY.\nThe delegates were fortunate to have Jean de Villiers as a key note speaker at the closure. His message was also about people, attitudes, teamwork and communication.\nMr Philip Von Memerty - Chairperson of Hog Day 2019 - stated that he believed it was a successful conference, there was a blend of youth and experience and interaction was good. He expressed his heartfelt gratitude to every sponsor, to Duncan, Lourika, Danél, Nicole and the entire “Lionel's Team” for all the contributions.\nHis closing comments were “GO FOR THE BIG GAME – GIVE IT ALL!”", "pred_label": "__label__POS", "pred_score_pos": 0.542847752571106}
{"content": "Neurotechnology's New Wave, Part II: Value, Acceptance, and Clinical Applications\nJune 18, 2006\nNeurotechnologic devices are proving themselves in clinical medicine. Many of these devices offer several distinct advantages over traditional pharmaceutical-based therapies: their effects are reversible, they are often cheaper than pharmaceuticals, and they solve therapy adherence issues. \"If a problem occurs, you can turn off the device; or if the disease evolves over time, you can dynamically adjust the device,\" explained Ali R. Rezai, MD, chairman of the Center for Neurological Restoration at the Cleveland Clinic.", "pred_label": "__label__POS", "pred_score_pos": 0.8909433484077454}
{"content": "Abstract\nOBJECTIVES: Overutilisation of antibiotics may contribute to the emergence of antimicrobial drug resistance, a growing international concern. This study aimed to analyse the performance of UK general practices with respect to antibiotic prescribing for respiratory tract infections (RTIs) among young and middle-aged adults. SETTING: Data are reported for 568 UK", "pred_label": "__label__POS", "pred_score_pos": 0.9887946844100952}
{"content": "Abstract\nInternalization of ADAMTS13 by macrophages may contribute to its clearance from the circulation. Here we investigated endocytic mechanisms that contribute to the uptake of ADAMTS13 by macrophages. Human monocyte-derived macrophages were used to monitor the uptake of fluorescently labeled recombinant ADAMTS13 by flow cytometry. Internalization of ADAMTS13 was blocked upon", "pred_label": "__label__POS", "pred_score_pos": 0.9454160928726196}
{"content": "Abstract\nHolomycin is a dithiolopyrrolone antibiotic natural product produced by Streptomyces clavuligerus, ATCC 27064. This paper reports on the identification of a gene cluster from S. clavuligerus that directs holomycin biosynthesis. Heterologous expression of the cluster in S. albus then induced the production of holomycin. Bioinformatics analysis of the gene cluster revealed that holomycin was assembled by a single multidomain non-ribosomal peptide synthetase (NRPS) consisting of heterocyclization, adenylation, and thiolation domains (Cy-A-T), a free-standing condensation domain, two thioesterases, five tailoring enzymes involved in oxidative reactions and two regulatory and transcriptional genes. Knock out of the gene, HomI, completely abolished the production of holomycin, which is consistent with its role as a key biosynthetic gene and is likely involved in the formation of the disulfide bond generating the final precursor, holothin.\nKeywords Dithiolopyrrolone Holomycin NRPS Heterologous expression Biosynthesis", "pred_label": "__label__POS", "pred_score_pos": 0.6816853880882263}
{"content": "Green infrastructure is a cost effective method to manage stormwater by preventing pollution of our waterways before it happens. NYC’s urban environment is lined with pavement, concrete, and empty roofs that drain rainfall immediately to sewers. In contrast, more porous surfaces, such as vegetated roofs, street trees, bioswales and rain gardens, can slow or capture stormwater before it enters the sewer system. These types of green infrastructure also have co-benefits, like filtering air and reducing local heat during the summer. When the community is a stakeholder in its development, green infrastructure can also mean green jobs and community cohesion.\nTell the Mayor to Cut the Crap and make green infrastructure a priority in NYC!\nWe’re at a pivotal moment for green infrastructure. NYC is currently not on track to meet its modest development goals. The City Council has held a hearing on new green roof legislation. Help us make sure this legislation creates opportunity, requirements and incentives for green roofs.", "pred_label": "__label__POS", "pred_score_pos": 0.7614052295684814}
{"content": "By Bill Hornbarger, Chief Investment Officer at Moneta\nMarch marked the 10th anniversary of the low on the S&P 500 during the Global Financial Crisis. Since then, the index produced an annualized total return of 16.7% during one of the best-performing decades for risk assets returns on record.\nThe market rebound in late December last year continued through March, but relied heavily on confidence in central banks to contain downside risks of slowing global growth. The most significant risk to this rebound and low volatility is central banks losing control of this narrative.\nIn his recent 60 Minutes interview, Federal Reserve Chair Jerome Powell said, “Growth has slowed in some major economies.” At the Federal Open Market Committee (FOMC) meeting in March, Fed policymakers signaled zero rate increases in 2019 and just one hike in 2020, down from the previous guidance of two hikes in 2019 and one in 2020. This change in forward expectations aligns interest rate expectations with the current, observed slower growth momentum. Federal fund futures signal an even more accommodative monetary policy stance, forecasting a full 25 basis point rate cut by year-end.\n(see chart below)\nWhile March provided plenty for investors to digest, risk assets proved resilient. Ongoing protests in France, uncertainty around Brexit, back-and-forth U.S.-China trade negotiations and weaker domestic growth and inflation data did not deter the rebound in risk assets.\nThe S&P 500 Index rallied 1.9% in March and now stands 20.6% above its December lows. The forward price-to-earnings valuation multiple on the S&P 500 Index increased 1.6 to 17.1 during the first quarter and explained a large portion of those returns.\nAs earnings season unfolds, it will be instructive to focus on earnings growth and compare full-year earnings guidance to current estimates. Bloomberg consensus estimates lowered their earnings growth forecast for 2019 from 8.1% to 2.4%, but those forecasts also call for approximately 2.0% margin expansion from 2018(1).\nCorporate profit trends will be particularly important since recent bank lending surveys indicated tightening of lending standards. If lending standards do not ease quickly, corporations will need to offset higher borrowing costs by reducing capital expenditures, labor costs or cutbacks in other areas. While we expect corporate profit margins to fluctuate over short periods, we acknowledge they are currently high by historical standards in the face of a slower growth outlook.\nIn contrast to the risk-on sentiment in the equity market, returns in fixed income markets were consistent with mounting growth concerns. High yield credit spreads widened 0.1% to 3.9%, and the 10-year U.S. Treasury yield fell 0.3% to 2.41%. The spread between two-year and 10-year U.S. Treasury yields fell 5.0 basis points to 13.9 in March.\nThis month, Fed policymakers outlined a roadmap for balance sheet normalization: slow the pace of reduction starting in May and conclude balance sheet reduction by the end of September. The yield curve continued to flatten in Q1. We believe inversion on the front end of the yield curve is still sending Fed policymakers a message that monetary conditions remain too tight.\nWhile still a low probability, the yield curve could be signaling that monetary policy cannot generate sustained economic growth. For example, starting in mid-2018 (before the European Central Bank ended its asset purchase program), the rise in long-term Treasury yields began to slow as investors called the synchronized growth narrative into question. This indicates that accommodative monetary policy may need concurrent and forward-looking economic indicators to justify a further sustained rally in risk assets.\nMarket Outlook\nDespite the rebound in equity valuations, we remain constructive on underlying fundamentals while acknowledging that elevated valuations likely reduce upside potential from here absent meaningful and sustained earnings growth.\nExpectations still call for the U.S. economy to grow approximately 2.1% in 2019. Fed policymakers took steps at the March meeting to accommodate slowing growth momentum. Effects of fiscal and monetary accommodation are still working through China, and the European Central Bank recently announced a new term lending facility intended to spur loan growth in the region. Although the U.S.-China trade conflict remains fluid, U.S. officials extended the deadline for further negotiations. Both mounting populism in Europe and Brexit negotiations remain sources of headline risk for markets and bear monitoring.\nInvestors should be patient and adhere to a well-constructed, diversified investment portfolio anchored to their goals and time horizon. Despite elevated uncertainty, we do not find compelling reasons at this time to justify overriding our asset allocation methodology. While corrections like the one experienced in the fourth quarter of last year are unnerving, they are a natural part of the market cycle and often represent a process of resetting valuations.\nGlobal Highlights\nMarket Snapshot\nFixed Income Longer-dated U.S. Treasury yields rose and the yield curve steepened due to stronger-than-expected GDP data and diminished concern over tariff issues with China. High yield corporate bonds were the best performing fixed income asset class as lower quality credits continued to benefit from healthy risk appetites. Municipal bond prices benefitted from constrained supply. International unhedged and emerging markets debt posted negative returns as the U.S. dollar rallied. Equities U.S. equities continued their advance as fewer macroeconomic headlines resulted in positive sentiment. Growth broadly outperformed value during the month. Industrials, Utilities and Technology outperformed the broader index. Developed international equities advanced, but were subdued by weak economic data and concerns of slowing growth. Emerging market equities posted modest gains as attractive valuations and a backdrop of economic reforms in China supported returns. Real Assets Real assets were higher for the month with the exception of international REITs, which fell moderately due to global growth concerns. Commodities were the best performing real asset class for the month. Lower-than-expected oil supply was supportive for prices throughout the period. Master limited partnership (MLP) business ventures advanced modestly on higher oil prices, but mixed earnings reports, rising interest rates and pipeline delays muted returns. Financial Market Performance\n1 Bloomberg © 2019 Moneta Group Investment Advisors, LLC. All rights reserved. These materials have been prepared for informational purposes only based on materials deemed reliable, but the accuracy of which has not been verified. Past performance is not indicative of future returns. These materials do not constitute an offer or recommendation to buy or sell securities, and do not take into consideration your circumstances, financial or otherwise. You should consult with an appropriately credentialed investment professional before making any investment decision.", "pred_label": "__label__POS", "pred_score_pos": 0.6727534532546997}
{"content": "Mr. Speaker, ten years after its first forum on women, the Centrale de l'enseignement du Québec is organizing its second gathering, this week, under the theme: \"Power, a non-traditional job\".\nAware of women's limited access to the various forms of power, the participants will cover four themes: women's ability to act in their personal lives, their perception of autonomy, political power and the economy.\nDespite the vitality of the women's movement, women have yet to be recognized as a social force that cannot be ignored. Thérèse Casgrain deeply believed that women's power had to be gained alongside and not in opposition to men's. So, men will be invited to attend on the final day and take part in special workshops.\nWomen's power to be, act and imagine is a major asset to the development of our society. Women must take their rightful place.", "pred_label": "__label__POS", "pred_score_pos": 0.9360888600349426}
{"content": "Abstract\nCost-effective heat mitigation strategies are imperative for maintaining milk production and dairy farm profitability in the U.S. with projected climate change. This study investigated the cost-effectiveness of four heat abatement strategies, including Minimal (open barn or shading), Moderate (forced ventilation), High (fans and misting), and Intense (air conditioning). Heat stress and subsequent impacts on milk production per cow were predicted across nine climatic regions in the U.S. for early (2015 to 2034), mid (2045 to 2064) and late (2081 to 2100) 21\nst century, using downscaled climate projections. Heat abatements were used to adjust predicted milk production losses and illustrate the potential to reduce milk production losses due to heat stress. Economic analysis included a cost-benefit ratio calculation associated with the implementation of each heat abatement. Results showed that milk production losses were expected to accelerate across the U.S. at a mean rate of 174±7 kg/cow/decade, with the fastest rate in the Southeast region. Relative to Minimal heat abatement, Moderate, High, and Intense heat abatements increased annual milk production per cow by 3%, 4%, and 6% during early-21 st century, 3%, 6%, and 11% during mid-21 st century, and 3%, 8%, and 21% during late-21 st century, respectively. The cost effectiveness of different heat abatement strategies generally increased with subsequently stronger heat abatements. In mid- and late-21 st century, mean annual net values of High and Intense heat stress abatement implementation approached -$30 to $190 /cow and -$20 to $590 /cow, respectively, with the largest net annual benefit in late-21 st century under Intense abatement. Findings from the study demonstrate the value of using downscaled climate projections to shed light on local and regional strategies to abate heat stress on cattle and mitigate potential milk production losses due to climate change.", "pred_label": "__label__POS", "pred_score_pos": 0.6659373641014099}
{"content": "Abstract\nThis study was designed to compare the interactions of IL-2 and IL-15 with the IL-2Rβ and IL-2Rγ\nc subunits, as differences in receptor interactions between IL-2 and IL-15 might contribute to the functional differences between these two cytokines. The results suggest the existence of a human IL-15Rα subunit, although physical evidence of this molecule was not obtained. Proliferation of anti-CD3 (OKT3)-stimulated human PBL was compared for responsiveness to IL-2, IL-15, and F42K, an IL-2 mutant that does not bind the IL-2Rα chain. F42K was more potent than IL-15 in activating a dose-dependent response. This fact, along with Scatchard binding analyses of IL-15 on OKT3 blasts and YT cells revealing both high and intermediate affinity receptors, supports the existence of IL-15Rα on these cells. Additional characterization of the IL-15R utilized covalent cross-linking to affinity label IL-2R and IL-15R on YT cells and OKT3 blasts. Consistent with previously reported functional data, IL-2Rα was not co-precipitated from the [ 125I]IL-15 receptor-ligand complex, demonstrating that IL-15 does not interact physically with the IL-2Rα subunit. While IL-2Rα did co-precipitate with IL-2Rβ and IL-2Rγ c in the presence of IL-2, IL-15Rα did not co-precipitate with the IL-2Rβ/γ c complex. Finally, YT cells equilibrated with IL-2 and then precipitated through IL-2Rβ showed that IL-2Rβ and IL-2Rγ c co-precipitate in a 1:1 ratio, while only IL-2Rβ was found in the immunoprecipitates of YT cells equilibrated with IL-15. This indicates that IL-15 creates a less stable bridge between the IL-2Rβ and IL-2Rγ c chains than does IL-2 on YT cells. This result was identical for both surface-iodinated YT cells and immunoprecipitates that were probed for IL-2Rβ and IL-2Rγ c on Western blots.\nOriginal language English (US) Pages (from-to) 1339-1348 Number of pages 10 Journal Journal of Immunology Volume 156 Issue number 4 State Published - Feb 15 1996 ASJC Scopus subject areas Immunology and Allergy Immunology", "pred_label": "__label__POS", "pred_score_pos": 0.6874257326126099}
{"content": "d'Arta trims 1.6MW of electricity with Demand Side Response Belgian food manufacturer embraces Demand Side Response to control costs and deliver on sustainability Offsetting rising electricity costs\nThe processing, deep-freezing and cold storage of vegetables uses huge amounts of energy, making it the largest monthly cost for d’Arta. To offset rising electricity costs, the business wanted to explore Demand Side Response (DSR).\nIsolating flexible power\nTogether with the d’Arta team, REstore (now part of Centrica Business Solutions) performed an on-site DSR audit. This revealed the potential for 1.6 MW of power curtailment in three different cold storage rooms at the plant.\nThese heavily insulated warehouses have a substantial thermal buffer able to keep temperatures low for a few hours without the need for extra cooling. However, the audit also revealed the identified flexible power did not fully comply with the technical specifications imposed by the Transmission Supply Operator. To address this, Centrica Business Solutions demonstrated its value added as an aggregator by integrating d’Arta’s power curtailment potential in its broader portfolio of participating companies using its FlexPond™ platform.\nThe results\nThrough Centrica Business Solutions’ DSR programme, d’Arta is able to curtail 1.6 MW of electricity consumption and generate payments to offset rising electricity costs.\nThe project protects d’Arta’s production. Using highly automated food processing and logistics systems, d’Arta is able to produce and distribute over 4,000 pallets of ready-to-eat meals and packaged vegetables every week. Isolating the flexible power for DSR purposes from the freezer production lines enables d’Arta to maintain the cooling processes for both cold storage facilities and for the production lines in the same machine room.\nThe benefits aren’t just financial. The DSR solution lowers the company’s carbon footprint and helps to curb global climate change.\nWhy Centrica Business Solutions? Centrica Business Solutions respects pre-set conditions for curtailment at all times. There is no impact on production and high-quality standards are always maintained. Demand Side Response facilitates the further development of renewable energy. It lowers industry’s carbon footprint. It helps to curb global climate change. Demand Side Response generates significant recurring revenue. Industrial consumers can use these earnings to reduce their energy bill.", "pred_label": "__label__POS", "pred_score_pos": 0.610028088092804}
{"content": "We're an affiliate\nWe hope you love the products we recommend! Just so you know, we may collect a share of sales or other compensation from the links on this page. There is no cost to you. Thank you if you use our links, we really appreciate it!\nYou just acquired a peloton bike for your personal work out sessions. If you do not have a dedicated gym area, you would be wondering where to place it to get the maximum use of it while protecting your flooring.\nSo, can you place your peloton on the carpet?\nThe answer is yes. You can place your peloton on carpet, but making certain precautions such as placing some plywood underneath for stability, and adding a mat on top to protect your carpet from sweat.\nThis article discusses why you need a carpet/mat for your peloton and other related questions. Keep reading to learn more.\nWhy Would You Need A Carpet For Your Peloton?\nIf you do not have a dedicated gym area, it is recommended that you place your peloton on a carpet. Even with a gym area, it is still good that you purchase a dedicated peloton mat like this.\nSo, why is it wise to place a peloton on a carpet? First, we want to consider the question about flooring. Flooring is an expensive investment, and you must maintain it so that the floor can last for long looking as good as it was new.\nThat said, it would be insane to use a peloton on bare hardwood flooring, for instance. Pelotons can cause immense damage to the floor given the intense friction from the pedaling, chain drive spillages, and even dust buildup.\nDiscussed below are details of how the carpet will be of help.\nAs you move the bike around or pedal, the wheels will be spinning, causing a lot of friction and even scratches. If the bike is resting on a bare floor, be ready to see some scratches and dents, especially for hardwood and vinyl flooring. Thus, a carpet would come in handy in minimizing such damage. During the spinning, some dust might be produced, and at times, lubricants from chains may spill. It would be better if all these fell on the carpet, as opposed to falling directly on your expensive flooring. During the workout, a lot of sweating takes place. The carpet will come in handy in absorbing the sweat drops from falling on the bare floor and causing slipperiness. Given the noise produced when spinning the peloton, you may want an absorber so that you do not cause unnecessary disturbance. A carpet is a perfect noise absorber. Finally, bare floor may sometimes get slippery. To maintain balance while working out on a peloton, a carpet would be your perfect bet. It will give you safety, and especially with intense and pumped up workouts. What Precautions Should You Take While Using A Carpet?\nWhen working out on a peloton placed on a carpet, you may notice some wobbling, especially when doing intense workouts. This is due to uneven carpet surface. However, do not worry, as there is a remedy.\nYou can place a plywood board under your peloton on the carpet. This will reduce the wobble significantly, and allow you to pedal smoothly without instances where you are forced to slow down.\nThus, even with intense workouts, vibrations on the floor are reduced significantly. Second, they provide your bike with extra cushioning, stability and noise reduction. Lastly, there is the question about protecting the carpet from sweat and wear and tear because of friction.\nIf you feel like using a mat and plywood at the same time is too much for you, you can still buy a heavy-duty mat. This one will play the role of both, although compared to the plywood it might be less stiff.\nAre All Carpets Safe For Placing A Peloton?\nWe have seen that you can place your peloton on the carpet to protect the floor and for stability of the bike, as well as safety during workout sessions. However, not all carpets will have these provisions. Below are some considerations to make as you choose the right carpet for your peloton.\nA thick carpet will do a good job at protecting your flooring. Additionally, it is more comfortable, does not curl up, and it always lays flat easily. Additionally, choose a sturdy and durable material that can withstand the wear and tear subjected to it from the peloton at work. The carpet should be large enough to accommodate your peloton. Luckily, once you have your peloton at home, figuring out the right size of carpet to buy will not be hard. Related Questions How can you make a peloton stable on the carpet?\nA peloton placed on a carpet might not be completely stable because carpets may tend to have uneven surfaces. The best thing to do is place a plywood board on the carpet and a bike mat on the plywood before placing the peloton. This way, you won’t feel any wobbling.\nWhich room would be ideal for placing your peloton?\nIf you do not have dedicated gym space, you may face a dilemma on where to place your bike. You will want a room with less distraction so that you focus on your session. Whatever room you choose, a power socket should be near so that you do not overstretch your bike’s wires. Finally, choose a room with proper ventilation and air condition. You know why this is very important.", "pred_label": "__label__POS", "pred_score_pos": 0.6713365912437439}
{"content": "Qualifying For Social Security Disability With Psychological Problems? Question: One of my employees is having severe emotional problems that are interfering with his ability to do his job and get along with others. He told me he doesn’t think he can keep his job, based on his severe depression. Can people with psychological problems really qualify for Social Security disability benefits? Answer: The situation you are describing isn’t entirely uncommon. Over 25% of our nation’s adults struggle with mental illness. There are a significant number of individuals with severe mental impairments that find it nearly impossible to work due to their psychological instability.\nWithin South Florida, individuals diagnosed with a severe mental impairment, may typically experience problems interacting with other employees, following instructions, working long periods of time, and managing average stress on-the-job. If someone has been diagnosed with a mental impairment, he may be eligible to apply for Social Security disability benefits in Florida. However, navigating the procedures of the Social Security criteria is quite stressful and cumbersome process.\nIn this case, receiving Social Security disability benefits may be a possibility for someone who has a severe mental impairment. Contact the Law Office of David Benenfeld for a FREE consultation to help you with your claim. Call: 954-807-1334.", "pred_label": "__label__POS", "pred_score_pos": 0.8874228000640869}
{"content": "PURPOSE: Image acceleration provides multiple benefits to diffusion MRI, with in-plane acceleration reducing distortion and slice-wise acceleration increasing the number of directions that can be acquired in a given scan time. However, as acceleration factors increase, the reconstruction problem becomes ill-conditioned, particularly when using both in-plane acceleration and simultaneous multislice imaging. In this work, we develop a novel reconstruction method for in vivo MRI acquisition that provides acceleration beyond what conventional techniques can achieve. THEORY AND METHODS: We propose to constrain the reconstruction in the spatial (k) domain by incorporating information from the angular (q) domain. This approach exploits smoothness of the signal in q-space using Gaussian processes, as has previously been exploited in post-reconstruction analysis. We demonstrate in-plane undersampling exceeding the theoretical parallel imaging limits, and simultaneous multislice combined with in-plane undersampling at a total factor of 12. This reconstruction is cast within a Bayesian framework that incorporates estimation of smoothness hyper-parameters, with no need for manual tuning. RESULTS: Simulations and in vivo results demonstrate superior performance of the proposed method compared with conventional parallel imaging methods. These improvements are achieved without loss of spatial or angular resolution and require only a minor modification to standard pulse sequences. CONCLUSION: The proposed method provides improvements over existing methods for diffusion acceleration, particularly for high simultaneous multislice acceleration with in-plane undersampling.\nJournal article\nMagn Reson Med\n07/2019\n82\n107 - 125\nGaussian processes, SMS, diffusion MRI, image acceleration, k-q reconstruction", "pred_label": "__label__POS", "pred_score_pos": 0.9971234798431396}
{"content": "Social isolation is a public health crisis. Social isolation is defined as an absence of meaningful social relationships. Studies have found the health risks of social isolation can be more harmful than obesity, and prolonged isolation is equivalent to smoking 15 cigarettes a day. In a united effort to help those affected, the foundations recently expanded\nConnect2Affect.org, which was originally launched by AARP Foundation in 2016. The site offers resources to address social isolation, including an assessment that individuals can take to find out if they or a loved one are at risk for social isolation and get guidance on how to strengthen their social bonds.\nFunded by AARP Foundation with the support of a grant from United Health Foundation, this report explores the impact of the COVID-19 pandemic on adults of all ages, to understand levels of social isolation during the pandemic, and to assess knowledge of how social isolation can impact a person’s health.", "pred_label": "__label__POS", "pred_score_pos": 0.6219631433486938}
{"content": "It is challenging to experimentally define an energy landscape for protein folding that comprises multiple partially unfolded states. Experimental results are often ambiguous as to whether a non-native state is conformationally homogeneous. Here, we tested an approach combining systematic mutagenesis and a Brønsted-like analysis to reveal and quantify conformational heterogeneity of folding intermediate states. Using this method, we resolved an otherwise apparently homogeneous equilibrium folding intermediate of Borrelia burgdorferi OspA into two conformationally distinct species and determined their relative populations. Furthermore, we mapped the structural differences between these intermediate species, which are consistent with the non-native species that we previously proposed based on native-state hydrogen exchange studies. When treated as a single state, the intermediate ensemble exhibited fractional Phi-values for mutations and Hammond-type behaviors that are often observed for folding transition states. We found that a change in relative population of the two species within the intermediate ensemble explains these properties well, suggesting that fractional Phi-values and Hammond-type behaviors exhibited by folding intermediates and transition states may arise more often from conformational heterogeneity than from a single partial structure. Our results are consistent with the presence of multiple minima in a rugged energy landscape predicted from theoretical studies. The method described here provides a promising means to probe a complex folding energy landscape.", "pred_label": "__label__POS", "pred_score_pos": 0.9615079164505005}
{"content": "Description\nOne of the most significant social psychological studies was conducted on the heels of the Holocaust and the atrocities committed during that period in history. Social psychologists questioned how individuals could blindly follow an authority figure’s demands to inflict harm.\nA brief summary of Milgram’s seminal research on obedience to authority. Describe Milgram’s methodology as well as his reults and his interpretation of those results. Discuss what current research has found regarding conforming to authority. Will individuals most tend to conform to authority? Why or why not? Does current research support or refute Milgram’s findings? Explain.", "pred_label": "__label__POS", "pred_score_pos": 0.7043229341506958}
{"content": "An uncommon situation unfolded recently as three local residents appeared to be targeted with paintball gun attacks. According to the Altoona Police Department, last week these three residents reported being shot by paintballs in three separate drive-by paintball shootings.\nOver the course of one evening, the paintball attacks took place in three different locations. Twice, a person on a bicycle was targeted, with the third occurrence involving a pedestrian. The police reported that all three vehicles gave the same description of the SUV that the paintballs originated from, a silver-colored SUV.\nWhile being shot with a paintball may not sound serious, being shot with a paintball, especially while biking can cause severe injuries. In addition to the soft tissue damage caused by the paintball’s impact, the impact could cause the bicyclist to lose control and crash. These crashes can cause abrasions, broken bones, head injuries, and even death.\nFor example, commenters on the Altoona Police Department’s Facebook page say that the first teenager went to the emergency room because of the injuries she sustained in the attack. The Altoona Police Department are still investigating this incident, and there has been no official update on this victim’s condition.\nThe perpetrators will likely be charged criminally, but it is through a personal injury lawsuit that these three victims can receive compensation for their injuries, even emotional, that resulted from these drive-by attacks. This is why, once the perpetrators are identified, these three victims should file a personal injury lawsuit against all the individuals involved.\nDepending on the circumstances, the shooter or shooters, the driver, and possibly even those in the vehicle may all be liable to these victims. The key will be identifying the facts of who did what, and then filing the lawsuit against all those involved.\nThe Altoona Police Department ask the public to call them if they have any information on any of these incidents or on the silver-colored SUV. And, once the perpetrators are caught, the victims of these incidents should seek to recover damages in a personal injury lawsuit.", "pred_label": "__label__POS", "pred_score_pos": 0.7230809926986694}
{"content": "Shareholder Disputes Unfortunately, shareholder disputes are a common part of business, but they don’t have to be debilitating to your enterprise. If you have a shareholder agreement in place, you’re already in a more positive position to resolve issues, but whether you do or not, you still may face the decision on whether to institute […]\nWiderman Malek Law Blog\nIn a perfect world, businesses would run seamlessly, shareholders would always agree on decisions, and there would never be legal actions based on claims between and among those who hold shares in the same enterprise. Alas, we do not live in a perfect world, and shareholder disputes are unfortunately a reality in many companies, large […]\nHaving a solid foundation is crucial to any business, and in the context of enterprises that have shareholders, one of the key components of that foundation is a shareholder agreement. In short, yes, you need one. A shareholder agreement is a voluntary and consensual contract among and between those individuals who hold shares in the […]", "pred_label": "__label__POS", "pred_score_pos": 0.9108891487121582}
{"content": "Improving primary care for patients with chronic illness is critical to improving healthcare quality, value and patient experience. Primary care providers are participating in several new payment models that emphasize quality and value. However, little is known about whether and how participation in these programs affects care delivery, specifically for patients with chronic needs.\nDori Cross, an assistant professor in the School of Public Health at the University of Minnesota, worked with a team of researchers to conduct in-depth interviews with 14 primary care practices participating in value-based payment models. The findings were recently published in the journal\nHealthcare.\nOf those interviewed, half of the practices had improved patient outcomes over time for their chronic disease patients (based on administrative claims data) and half did not.\nResearchers identified several strategies that differentiated practices with improved performance for chronic disease patients. Practices had to balance immediate care delivery needs while also creating new adaptive structures and processes to better respond to changing pressures and demands.\nKey strategies generated long-term value to practices by strengthening:\n- access and receptivity to new ideas for care delivery through external learning opportunities;\n- efforts to foster intrinsic motivation among providers and staff;\n- pursuit of new staffing and workflow models that integrated care management while delegating administrative requirements to external supporting organizations.\n\"Practices are serving an increasingly complex population while simultaneously complying with numerous new service and documentation requirements under value-based program models,\" said Cross. \"Those successful at improving outcomes for chronic disease patients under these models did so by pursuing a culture of change, with strategies that emphasized adaptiveness and creative use of resources.\"\nThese findings help inform payers and primary care practices seeking evidence-based strategies to foster a stronger delivery system for patients with significant healthcare needs.", "pred_label": "__label__POS", "pred_score_pos": 0.6791417598724365}
{"content": "The verb gustarhas a special structure in Spanish, and it forms a part of one of the grammatical subjects that presents the greatest problem for students, since it does not bear any grammatical similarity to English.\nOne of the first things that we learn in a new language is how to express likes and dislikes. \"I like Spanish,\" \"I like the culture,\" \"I like how it sounds,\" or \"I like to travel around South America\" are some of the most common answers to the question \"Why are you learning Spanish?\"\nWe use the verb\ngustar to express desires, dislikes, interests, preferences, and feelings.\nA normal statement in Spanish is formulated by a\nSubject + Verb + Complement.\nFor example,\nYo corro en el parque- I run in the park Ella come una hamburguesa- She eats a hamburger\nWith the verb\ngustar, the most important difference is that subject personal pronouns ( yo, tú, el, ella, usted, nosotros, nosotras, ustedes, ellos, ellas) are . Instead, it is necessary to use the corresponding indirect object pronouns not used (IO)for each person, preceded by the preposition \"a.\"\nThe structure is as follows:\nIndirect Object Pronoun (IO) + Gustar (in the 3rd person) + Complement\nFor example,\nA mí- I like ice cream me gustael helado A ti- You like Italian food te gustala comida italiana\nWith the verb\ngustar we need to differentiate between singular and plural objects. When the object is singular, we use gusta, and when it is plural, we use gustan.\nFor example,\nA mí- I like the book me gustael libro A mí- I like the books me gustanlos libros A ellos- They like the dog les gustael perro A ellos- They like dogs les gustanlos perros A nosotros- We like the beach nos gustala playa A nosotros- We like the beaches of Mexico nos gustanlas playas de México\nWe can also state that we like an activity with the form\ngusta.\nFor example,\nA mí- I like to eat ice cream me gustacomer helado A ustedes- You all like to listen to music les gustaescuchar música A nosotros- We like to run in the park nos gustacorrer en el parque And what do you like?", "pred_label": "__label__POS", "pred_score_pos": 0.8869187831878662}
{"content": "Millennials and Digital Communities Reshaping the Legal Profession in 2018 Date:February 26, 2018\nWhat’s Reshaping the Legal Profession in 2018?\nGranted, we are only two months into the new year. While there aren’t specific shakeups that haven’t already been identified in 2017, this year will be marked by two key shifts: 1) Millennial Attorneys, 2) Digital Communities\nMillennials (aka, individuals born between roughly 1980 and 2000) are literally taking over the world in 2018. They now makeup the largest generation — 92 million strong in the United States. Clients and colleagues are going to have to learn to live with them.\nThese legal professionals will be entering the workforce in their early to mid 20s through their early 30s. This new generation holds entry-level associate, paralegal, law clerk and legal support positions in law firms, corporate legal departments, the government and other practice environments. Despite the many negative stereotypes, law firm supervisors have found millennial attorneys to be smart, creative, optimistic, achievement-oriented and tech-savvy. Distinct from the Generation X attorneys, millennial attorneys are marked by a unique desire to seek supervisors and mentors to engage in their professional development. Key factors to consider:\nMillennials multi-task, communicate through email and text, and are accustomed to web-based delivery systems for CLEs and trainings. They will Google you, your clients…and everything. Pay attention to your digital footprint and digital presence. Millennials enter the legal practice anticipating demanding hours and billable hour quotas—what they expect that is different from previous generations of attorneys is a greater sense of flexibility and autonomy. They expect access and feedback—more than previous generations of attorneys, they want it more than just during their formal reviews and evaluations. Digital Communities have opened entirely new networks for lawyers to engage with. Networks have always been critical for lawyers. Being connected with different communities help lawyers find clients, make referrals, share insights, seek mentors, and develop personally as professionals.\nLinkedIn and other platforms (including platforms created by bar organizations) enable lawyers to not only look each other up, but to connect in new and meaningful ways.\nDigital communities also mean that there are entire networks of valuable information, now stored online in various quantities and qualities. Savvy lawyers should take advantage of this explosion of information and data.\nData now includes paper documents, electronic documents, emails, text messages, and social-media postings—generating about 2.5 exabytes daily—much of which is now stored virtually. This means that understanding and leveraging technology to protect information, to go through the discovery process, secure information, or to communicate privately will all require a new approach. Lawyers willing to embrace the latest technologies and innovations may find new opportunities in eDiscovery.", "pred_label": "__label__POS", "pred_score_pos": 0.6212536096572876}
{"content": "Better Listening & Communication\nGiven the fact that one political party has held the governorship and a super majority in both legislative chambers for many years, Utah is effectively a one-party-rule state. This has led to a lack of accountability which is typically exercised by opposing parties in a healthy multi-party system. One symptom of this is the failure of leaders to act for the benefit of all voters instead of their extreme base. With no fear of viable general election opponents, they only need to fear extreme challengers from within their own party.\nThe Legislature’s recent actions surrounding tax reform is a perfect examples of this. While tax reform was clearly necessary, a substantial increase in sales taxes on groceries was widely unpopular. The Legislature decided to ignore public sentiment and passed it anyway with little attempt to educate the public or involve them in the decision making process. This resulted in a grass-roots revolt in the form of a citizen referendum that forced the Legislature to walk away from tax reform sporting a historically low approval rating.\nWhat Can Be Done? Elect moderate candidates such as from the United Utah Party that can appeal to broad swaths of the Utah electorate and end one-party rule Demand better communication and responsiveness from Legislators by utilizing citizen initiatives and referendums when necessary", "pred_label": "__label__POS", "pred_score_pos": 0.526954174041748}
{"content": "Other parts of this series: Insurers and brokers can take three steps to implement effective sanctions risk strategies and support growth.\nIn our previous post, we discussed Know Your Customer (KYC) processes in insurance and pain points from a financial crime (FC) perspective. We highlighted key challenges and pain points in protecting insurers, brokers and customers from FC risks.\nThis post discusses in more detail how firms can enhance their current processes, better identify and mitigate risks for new or existing customers and how effective use of third-party vendors can provide increased benefits. Together, these measures can help insurers properly identify and mitigate potential sanctions and FC risks, supporting growth underpinned by effective compliance.\nImproving processes\nA key reason for process and data inefficiencies within insurance is the wide variation in processes between brokers and insurance providers.\nSolving this data problem can increase opportunities for automation, reducing inefficiencies and manual error. This in turn can support automated controls for insurers, permitting faster tracking of changes to customer accounts and support better identification of emerging risks.\nAutomated processes, combined with data hygiene, allow the real-time controls necessary to support digital FC controls, including sanctions screening, where incorrect information can cause delays, increase false positives or obscure true positive matches on your books.\n1 Introducing innovation\nIn addition to improved processes, new innovative tools currently used to identify and mitigate FC risks can be applied to insurance as well. These tools cover three areas: Onboarding, ongoing customer KYC screening and FC threat identification. Screening for Sanctions, Politically Exposed Persons (PEPs) and Adverse Media, a key part of KYC processes is one such opportunity area. As discussed in our related post on screening, name matching, tracking appropriate lists automatically and appropriate alerting to focus on true matches are important elements in effective processes.\nWhereas tools today may require manual effort to complete screening and discounting, innovative alliances like Ripjar Ltd can help automate this process, speeding time to screen for Sanctions, PEPs or Adverse Media risk, removing false positives and allowing insurance compliance teams to more effectively identify and mitigate risk.\nLeveraging intelligent operations\nIn some instances, insurers and brokers may find it more effective to leverage efficient third parties to conduct their KYC, escalating alerts requiring business review or approval, and completing the process on their behalf. Accenture’s Compliance as a Service (CaaS) model is an effective tool for companies looking to outsource elements of their compliance monitoring, investigations and reporting services. Such a model delivers cost-effective risk management using intelligent operations, mitigating risk while allowing firms to continue their focus on strategic growth.\nInsurers and brokers face evolving FC risks due to the nature of their products and services. To better face these risks, firms have an opportunity to improve their anti-FC processes, leveraging innovative tools or working with innovative vendors and alliances. Leveraging the improvements from these changes can help insurers and brokers continue to secure their businesses in a cost-effective manner, without sacrificing adherence to regulatory requirements.\nAccenture’s experience in process transformation and anti-financial crime, with its ecosystem of innovative vendors and relationships, is well positioned to help the industry identify potential risks to their firms and to customers.\nTo find out more on the topic or how Accenture can help you strengthen your financial crime capabilities please contact one of our authors.\nReference “Accenture 2019 Global Risk Management Study – Insurance Report,” Accenture, November 2019. Access at: https://www.accenture.com/us-en/insights/financial-services/insurance-global-risk-study.", "pred_label": "__label__POS", "pred_score_pos": 0.5111273527145386}
{"content": "When connecting your Gusto and ZipBooks accounts, you may have noticed that contracted workers did not sync between the two apps. This is because 1099 contractors are handled differently than traditional employees—here's a little background:\nWhen distinguishing between employees and contractors, there’s more to consider than hours and pay schedules. Employees can be part-time and contractors can make more than salary. The IRS distinguishes between the two by whether the payer “has the right to control how the worker performs the services” or just to direct the result. Employees, essentially provide their services under direction. They receive W-2s as their year-end tax forms and are typically hired indefinitely. Independent contractors, also frequently called “freelancers” or \"1099s\" (because of the tax forms they receive), are hired to do a particular job or project. They are in control of how, when and where they perform their work, though the employer can accept or reject the result. They are professionals paid an agreed-upon rate for a particular service, and they do not receive a salary or employee benefits. Think graphic designers, copywriters, photographers, web developers, and event planners. Note: If any of your ZipBooks team members are already listed in Gusto as Contractors, select \"Don't add to Gusto\" to avoid duplicates.", "pred_label": "__label__POS", "pred_score_pos": 0.6847711801528931}
{"content": "Uber on Thursday reported that it lost $1.1 billion in the newly ended quarter as the pandemic walloped its ride-hailing business while boosting its food delivery service.\nRevenue in Uber’s mobility unit was down 53 percent from the same quarter last year, while money taken in from Uber Eats, which includes delivering restaurant meals or other orders, more than doubled, according to the San Francisco-based company.\nThe third-quarter loss was marginally more distinguished than in the same period last year.\n“Despite an uneven pandemic response and broader economic uncertainty, our global scope, diversification, and the team’s tireless execution delivered steadily improving results,” chief executive Dara Khosrowshahi stated in an earnings release.\nUber shares that had been buoyed by the triumph of an initiative that lets drivers remain classified as independent contractors in California wobbled in aftermarket trades before edging slightly higher.\nDemand for rides directly correlates to pandemic lock-down restrictions in cities, and Uber’s mobility and delivery units are positioned to take advantage of returns to pre-virus lifestyles, Khosrowshahi said in an earnings call.\n“Uber is becoming the go-to app for getting around or getting something delivered to your door in 30 minutes,” Khosrowshahi stated.\nThe global COVID-19 pandemic has set back Uber’s efforts to drive into profitability, but executives announced they remain optimistic.\n“As consolidated growth returns, it will return to a more profitable foundation,” stated chief financial officer Nelson Chai.\nUber’s future was brightened this week with the passage of a California referendum allowing it and other “gig economy” operators to keep their contractor-driver business model.\nThe measure known as Proposition 22 effectively overturns a state law that would require the ride-hailing firms and others to reclassify their drivers and provide employee benefits.\nNecessary cookies are absolutely essential for the website to function properly. This category only includes cookies that ensures basic functionalities and security features of the website. These cookies do not store any personal information.\nAny cookies that may not be particularly necessary for the website to function and is used specifically to collect user personal data via analytics, ads, other embedded contents are termed as non-necessary cookies. It is mandatory to procure user consent prior to running these cookies on your website.", "pred_label": "__label__POS", "pred_score_pos": 0.6801042556762695}
{"content": "Abstract\nTo address the illicit cigarette trade, the European Union (EU) has signed agreements with the four major Transnational Tobacco Companies (TTCs) that involve establishing extensive systems of cooperation. All agreements foresee two types of payments: annual payments (totalling US$ 1.9 billion over 20 years) and supplementary seizure payments, equivalent to 100% of the evaded taxes in the event of seizures of their products. While limited by the fundamental lack of transparency in this area, our analysis suggests that these agreements have served largely to secure the TTCs' interests and are threatening progress in tobacco control. The seizure payments are paltry and a wholly inadequate deterrent to TTC involvement in illicit trade. Despite the agreements, growing evidence indicates the TTCs remain involved in the illicit trade or are at best failing to secure their supply chains as required by the agreements. The intention of the seizure-based payments to deter the tobacco industry from further involvement in the illicit cigarette trade has failed because the agreements contain too many loopholes that provide TTCs with both the incentive and opportunity to classify seized cigarettes as counterfeit. In addition, the shifting nature of cigarette smuggling from larger to smaller consignments often results in seizures that are too small to qualify for the payments. Consequently, the seizure payments represent a tiny fraction of the revenue lost from cigarette smuggling, between 2004 and 2012, 0.08% of the estimated losses due to illicit cigarette trade in the EU. Our evidence suggests the EU should end these agreements.\nOriginal language English Pages (from-to) 254-260 Journal Tobacco Control Volume 25 Issue number 3 Early online date 28 May 2015 DOIs Publication status Published - May 2016 Keywords illicit cigarettes", "pred_label": "__label__POS", "pred_score_pos": 0.8903944492340088}
{"content": "Homepage At a Glance\nThe\nStrategic Investment Fund (SIF) provides funding to support key initiatives of the University of Virginia’s 2030 Plan. Originally developed in 2016, the SIF provides funding that currently supports 48 distinct awards totaling just under $640 million dollars since inception. Projects will be selected for funding by the SIF Oversight Committee (SOC) through two mechanisms: a formal proposal and review process, and by opportunistic investment to support the strategic plan.\nThe SIF award funding is approximately evenly divided among three categories: research and research infrastructure, academic excellence, and access and affordability. A resoundingly successful component of the SIF program involves matching awards, including, in particular, the Bicentennial Scholars and the Bicentennial Professors Funds. Over sixty percent of the SIF funds awarded to date are being matched to varying degrees by philanthropic gifts dedicated to these two programs, thereby increasing the return on investment.\nThe projects that are funded by the SIF undergo periodic post award assessment by the Post-Award Assessment Committee (PAC) to ensure programmatic due diligence and adherence to the highest standards of stewardship and fiduciary responsibility.\nSupporting the vision for a great and good University\nIn 2019, the University's Board of Visitors approved a proposal that the\nStrategic Investment Fund (SIF) be used to fund the University’s 2030 strategic plan.\nThe\n2030 strategic plan is built around four goals: Strengthen the foundationof the University by both attracting talented and diverse students, faculty and staff, and supporting them. Cultivate a vibrant communityand build connections with our neighbors, alumni and more. Enable discoveries“that enrich and improve lives” by becoming an international leader, supporting interdisciplinary work, and “approaching all learning as an opportunity for discovery. “ Make UVA synonymous with service” by offering a great value to our students, providing affordable health care to our community and leading economic development. For additional information, please email [email protected]", "pred_label": "__label__POS", "pred_score_pos": 0.8341556191444397}
{"content": "The New York State Department of Financial Services (DFS) has extended emergency regulations issued in March requiring insurers to waive cost-sharing for COVID-19 testing and for all telehealth services during the current emergency.\nOriginally set to end last week, these cost-sharing waivers have now been extended until at least September 9, 2020. DFS guidance reflecting the extended dates can be found here.\nGNYHA appreciates DFS’s actions to facilitate improved access to these important services.", "pred_label": "__label__POS", "pred_score_pos": 0.9801795482635498}
{"content": "DUMP TRUCK INSURANCE\nDump truck coverage falls under the general category of commercial vehicle insurance. Like any commercial vehicle, owners of dump trucks are required to have liability insurance coverage before these trucks can be legally driven or used for jobs.\nThis coverage is particularly necessary as mishaps in these heavy-duty vehicles can lead to extensive damages. Because dump trucks are intended mainly for off-road use, their design is often such that a collision with a car can have deadly results. In fact, the Bureau of Labor and Statistics reports an average of one dump-truck related fatality every week in the United States.\nWhat Does Dump Truck Insurance Cover?\nA basic commercial dump truck insurance policy will provide the mandatory coverage required to operate these commercial vehicles. This includes the minimum bodily injury and property damage liability coverage amounts required by state law.\nTo ensure that your finances are secure and that your business is properly covered, you may want to consider building a basic commercial vehicle policy. Most commercial truck insurance companies provide the following additional coverage options that you can include in your dump truck policy:\nNon-trucking insurance: This coverage is designed for independent owner/operators with contract jobs. It provides liability insurance if you should be involved in an accident in your truck during off-work hours.\nMotor truck general liability insurance: This coverage will protect you from liability for damage you cause to your customer’s property while operating your vehicle on their grounds.\nPhysical damage insurance: This additional coverage provides compensation for any damage to your dump truck, and is usually required by dealerships if you are leasing your vehicle.\nMotor truck cargo insurance: If the cargo you will be hauling on your truck is valuable, you may be required to carry motor truck cargo insurance.\nCollision insurance: This will cover the repair of damage to your dump truck if you collide with another vehicle or object.\nFire and theft insurance: This comprehensive insurance will provide compensation for damages to your vehicle from fire or theft.\nEnvironmental insurance: This insurance will cover certain pollution-related losses and fines and the costs for restoration and clean-up, if necessary.\nRental reimbursement / downtime insurance: If your truck is damaged in an accident, this coverage will allow you to continue your business operations while your truck is being repaired or will cover business losses if continuation is not possible.\nOff-season comprehensive only insurance: If your business is seasonal, this will save you money while protecting your vehicle while it is not in use.", "pred_label": "__label__POS", "pred_score_pos": 0.8580911755561829}
{"content": "FamilyMart Malaysia is supporting the movement to reduce food wastage with a commendable initiative called Do Good Save Food. Shoppers can enjoy 25% off selected items when purchasing on the same “Best Before” date from 4pm to 11.59am. The promotion is applicable at all outlets.\nHowever, the romotion is not in conjunction with other promotions or discounts in store and cannot be used together with other coupons /vouchers.\nThe implementation of sustainable business practices have become important as consumers are increasingly judging companies by how sustainable they are.", "pred_label": "__label__POS", "pred_score_pos": 0.6041527986526489}
{"content": "Reptiles represent a phylogenetic lineage that provides a unique link between ectothermic anamniotes and endothermic amniotes. Compared to mammalian and avian species, our understanding of the reptilian immune system is greatly lacking. This gap in knowledge is largely due to an absence of established immune-based assays or specific reagents for these species. In the present study, brown watersnakes () were live-captured in the wild, sexed, weighed, measured, bled via the caudal vein, and released. At 24 hr post-collection, peripheral blood leukocytes were enriched and evaluated with an established mammalian lymphocyte proliferation assay. Snake peripheral blood leukocyte enrichment yielded >90% lymphocytes with viabilities averaging 81.5%. Baseline physiologic data for , including hematology and total solids, leukocyte differentials, cell recovery, and plasma biochemistry, were also collected. Cells cultured with Concanavalin A exhibited significantly increased proliferation at both 72 and 96 hr. These preliminary results show that enriched peripheral blood from wild-caught provides a sufficient yield of leukocytes that can be cultured and functionally evaluated using a standard mammalian immune-based assay.\nReferences\nPubMed", "pred_label": "__label__POS", "pred_score_pos": 0.9888108968734741}
{"content": "Aseptic Non Touch Technique (ANTT) is a unique Clinical Practice Framework for ensuring high standards of aseptic technique and has been shown to help reduce Hospital Acquired Infections (HAI).\nANTT is used for all invasive procedures from major surgery to community care. It has become the most widely used standard for aseptic technique in healthcare internationally and is being established as a universal practice language for aseptic technique.", "pred_label": "__label__POS", "pred_score_pos": 0.5818074941635132}
{"content": "A polyimide is a specific type of polymer produced from diamines and dianhydrides. Polyimides may be thermoplastic, with a high melt viscosity requiring high pressure to form molded parts. Polyimides may also be thermosetting, whereby imide oligomers are crosslinked into a three-dimensional network. Leading markets segment for polyimides include molding resins, films, fibers, advanced composites, wire enamels, foams, coatings and adhesives.\nDue to the excellent electrical and physical properties, polyimides are used in aerospace, electronics, automotive, and various other industrial applications. Electronics is the fastest-growing end user segment for polyimides and this trend is anticipated to continue in the future. Polyimide films are used to make flexible printed circuits for laptops, smartphones, tablets, wearables and other devices. Transparent polyimide films are of interest as it will be a substitute for substrates in flexible, lighter-weight flat panel displays, imaging sensors, solar cells, and other products.\nAccording to Gen Consulting Company, global polyimide market is projected to grow at a CAGR of 7.2% during the forecast period 2020-2026. The polyimide market is segmented on the basis of product, application, and region. The report offers a breakdown of market shares by product, including PI Film, PI Resin, PI Foam, PI Fiber, PI Varnish. By application, the polyimide market is classified into Aerospace, Electronics, Automotive, Industrial. On the basis of region, the polyimide industry is analyzed across North America, Europe, Asia-Pacific, South America and MEA (the Middle East, and Africa). North America dominates the global demand for polyimide and this trend is anticipated to continue during the forecast period. As the third largest polyimide market in the world, Asia Pacific is showing the fastest growth rate primarily owing to huge demand in China.\nBy Product:\n- PI Film\n- PI Resin\n- PI Foam\n- PI Fiber\n- PI Varnish\nBy Application:\n- Aerospace\n- Electronics\n- Automotive\n- Industrial\nBy region, the market is analyzed across North America, Asia Pacific, Europe, Middle East & Africa and South America. This report forecasts revenue growth at global, regional & country level from 2020 to 2026.\n- North America (U.S., Canada, Mexico, etc.)\n- Asia-Pacific (China, Japan, India, Korea, Australia, Indonesia, Taiwan, Thailand, etc.)\n- Europe (Germany, UK, France, Italy, Russia, Spain, etc.)\n- Middle East & Africa (Turkey, Saudi Arabia, Iran, Egypt, Nigeria, UAE, Israel, South Africa, etc.)\n- South America (Brazil, Argentina, Colombia, Chile, Venezuela, Peru, etc.)\nThe market research report covers the analysis of key stake holders of the polyimide market. Some of the leading players profiled in the report include:\n- Boyd Corporation\n- CEN Electronic Material Co. Ltd\n- Changchun Hipolyking Co., Ltd.\n- Changshu Zhongxun Space Flight Insulating Material Co. Ltd\n- Compagnie de Saint-Gobain S.A.\n- Du Pont-Toray Co., Ltd.\n- DuPont de Nemours, Inc.\n- Ensinger Sintimid GmbH (HP Polymer Inc.)\n- Evonik Industries AG\n- Gabriel Performance Products, LLC\n- Guilin Electrical Equipment Scientific Research Institute Co. Ltd.\n- HD MicroSystems, LLC.\n- Hipolyking Polyimide Materials Co. Ltd\n- Honghu Shuangma Advanced Materials Tech Co., Ltd.\n- Huawei Polyimide Co., Ltd.\n- Huntsman Corporation\n- I.S.T Corporation\n- Imitec, Inc.\n- Jiangsu Aoshen Hi-Tech Materials Co., Ltd.\n- Jiangsu Shino New Materials Technology Co., Ltd.\n*list is not exhaustive, request free sample to get a complete list of companies\nThe base year of the study is 2019, and forecasts run up to 2026.\nResearch Objective\n- To analyze and forecast the market size of global polyimide market.\n- To classify and forecast global polyimide market based on product, application, and region.\n- To identify drivers and challenges for global polyimide market.\n- To examine competitive developments such as mergers & acquisitions, agreements, collaborations and partnerships, etc., in global polyimide market.\n- To conduct pricing analysis for global polyimide market.\n- To identify and analyze the profile of leading players operating in global polyimide market.\nThe report is useful in providing answers to several critical questions that are important for the industry stakeholders such as manufacturers and partners, end users, etc., besides allowing them in strategizing investments and capitalizing on market opportunities. Key target audience are:\n- Manufacturers of polyimide\n- Raw material suppliers\n- Market research and consulting firms\n- Government bodies such as regulating authorities and policy makers\n- Organizations, forums and alliances related to polyimide", "pred_label": "__label__POS", "pred_score_pos": 0.9452213644981384}
{"content": "Abstract\nAtrial fibrillation (AF) is the most common arrhythmia worldwide associated with significant morbidity and mortality and represents a significant health care burden. Goals of AF treatment include prevention of cardioembolic stroke using anticoagulation and device therapy and restoration of sinus rhythm using antiarrhythmic drugs or catheter ablation techniques. A comprehensive assessment of cardiac chamber size and function is often started with echocardiography as a first line diagnostic imaging strategy. Recently, innovations in advanced imaging using cardiac magnetic resonance (CMR) and cardiac computed tomography (CCT) provide a detailed characterization of atrial anatomy and have been shown to accurately exclude thrombus and guide left atrial appendage (LAA) closure or catheter ablation (CA) of atrial fibrillation. Compared to echocardiography, CCT offers an uncompromised spatial resolution and a fast dataset acquisition, with the disadvantages of the need of iodine contrast agent and radiation exposure. CMR, conversely, can rely on very high temporal resolution, the unique feature of tissue characterization and the absence of radiation exposure. However, the main drawbacks of this diagnostic tool are long scan times and low availability. This review will illustrate the vital role of multimodality cardiac imaging in the accurate identification of left atrial, pulmonary vein and LAA size and function, discuss advanced imaging techniques to rule out thrombus and highlight novel CMR and CCT techniques to guide catheter ablation of AF and LAA occlusion.\nASJC Scopus subject areas Radiology Nuclear Medicine and imaging Cardiology and Cardiovascular Medicine", "pred_label": "__label__POS", "pred_score_pos": 0.5554189682006836}
{"content": "Twenty-eight personal data breaches have been reported to The Office of the Data Protection Commissioner (ODPC) in the last two months up to 13 December 2018.\nThe number of breaches has increased slightly, when compared with the previous reporting period of 26 reported breaches over the two months up to 18 October. The increase is likely due to two factors: firstly, organisations are increasingly more aware of their legal obligation to report breaches; and secondly, certain organisations have erred on the side of caution by reporting incidents that do not necessarily meet the breach classification criteria.\nThe ODPC encourages all local organisations to continue with this cautious approach as this provides valuable intelligence to the real-world risks faced by local organisations.\nMost incidents reported to the ODPC were low-level with no further action required. However, the ODPC has a heavy caseload of ongoing investigations into breaches and complaints that do require significant further inquiry.\nAs with the previous reporting period, there have been a number of incidents where hackers have gained control of email accounts using social engineering techniques.\nGuernsey’s Data Protection Commissioner, Emma Martins commented on the role of breach reporting and organisations’ duty to consider the people affected.\n‘We continue to see local organisations engaging in their legal obligation to report data breaches to our office. This is an essential aspect of compliance as it requires organisations to proactively engage with the risks they face in protecting people’s personal information. It also ensures they robustly consider the impact a breach may have on the people whose data has been affected.’\nThe ODPC uses the breach report information received to shape activities, particularly its communications strategy and regulatory action plan. Understanding where organisations are vulnerable enables the ODPC to target its resources in the most effective way.\nThe ODPC is working to improve its online breach reporting mechanism and has asked for any comments to be submitted via enquiries@odpc.gg.\n— Personal data breach: legal criteria A personal data breach is defined in section 111(1) of the Law as any incident that meets the following criteria: “ a breach of security leading to the accidental or unlawful destruction, loss, alteration, unauthorised disclosure of, or access to, personal data transmitted, stored or otherwise processed”.\nThere will likely be a breach whenever\nany personal data is accidentally lost, corrupted or disclosed, or if someone accesses it or passes it on without proper authorisation to do so.\nHowever, organisations do\nnot have to report any incidents that meet the above criteria if the incident is ‘unlikely’ to result in a risk to the ‘significant interests’ of any person whose data has been affected by the incident. It can be difficult, and sometimes inappropriate, for organisations themselves to judge whether there is a risk to a person’s significant interests, so the ODPC encourages all incidents to be reported. ‘Significant interests’ explained A person’s ‘significant interests’ are defined in our local Law as any aspect of their life that could be put at risk due to their personal data being breached. This could include their physical safety, their reputation, and could extend to placing them at risk of identity theft, fraud, financial loss, psychological distress or humiliation. Action points for organisations after a personal data breach: Read: ODPC breach reporting guidance document(includes checklists and templates); Let ODPC knowthe breach has occurred – via the secure online breach reportingmechanism; Take steps to limit the damage. Where appropriate, advise any person who received data in error that they should delete the data and must not make use of or disclose the data to anyone else; Consider whether it may be necessary or appropriate to report the breach to any other regulatory or law enforcement agency; In some cases you will need to notify the personwhose data was disclosed in the breach; Ensure your organisation reviews and learnsfrom what has happened. Action ODPC take following a reported breach: They recordthe breach, securely and confidentially, and assessits severity; They contact the organisation to confirm receiptof the breach report and discuss what happens next(each report is assessed on a case by case basis); Where necessary the ODPC may need to communicatewith other data protection authorities, if the breach is likely to affect people outside of the Bailiwick.", "pred_label": "__label__POS", "pred_score_pos": 0.6880985498428345}
{"content": "Singapore, 8 September 2020–TIBCO Software Inc., a global leader in enterprise data, empowers its customers to connect, unify, and confidently predict business outcomes, solving the world’s most complex data-driven challenges. Today, TIBCO announced a three-year collaboration with the Faculty of Engineering Universitas Indonesia. This program will provide students with the technology skills to develop their data science skills and prepare them for future career success.\nThrough this collaboration with the Faculty of Engineering UI, TIBCO is equipping students with core data analytics skills that are a fundamental become requirement of the next generation’s workforce. “As organisations in Indonesia, and across the region, continue to move ahead with digital transformation, the need for highly specialized skills in data science grows. We see our collaboration with the Faculty of Engineering UI as mission critical in addressing the future data talent gap,” explained Nick Lim, TIBCO, general manager, Asia Pacific and Japan (APJ).\n“TIBCO recognizes the need to empower students by developing their critical data skills that will prepare them for meaningful and productive careers in engineering, management, data analytics, and systems design. Through the TIBCO Academic Alliance, we provide the technology to spark learning and innovation in classrooms, and prepare the workforce of tomorrow.”\nTIBCO and the Faculty of Engineering UI see this collaboration as an opportunity to train up to 500 students of from the industrial engineering major and will eventually include students from other faculties within UI. The program offers students school-based workshops and hands-on practice using cutting-edge technologies including TIBCO Spotfire®, offered for free through TIBCO’s Academic Alliance initiative.\n“This collaboration with TIBCO is in line with our commitment to academic excellence through private sector collaboration with leading technology companies, as we strive to maintain leadership in the global academic environment. Integrating academic learning with real-world practice is part of our overall efforts to nurture future-ready graduates,” said Amalia Suzianti, Head of Industrial Engineering Department, Faculty of Engineering UI. “With our partnership with industry experts such as TIBCO, we are optimistic that this innovative program will further strengthen our high-quality education for our students and provide them with the data analytics skills needed in today’s business environment.”\nTIBCO has a strong record of successful engagement with schools across the Asia Pacific region at post-secondary levels. These include collaborations with Nanyang Polytechnic, Singapore Polytechnic, and Institute of Technical Education in Singapore.", "pred_label": "__label__POS", "pred_score_pos": 0.7721494436264038}
{"content": "Waste Separation Fans\nACI is helping many companies with innovative solutions to recycling issues, particularly in the area of waste separation.\nFor example, a waste separation fan placed horizontally across a drop enables all ‘light’ material to be caught by the airflow and blown into a collection bin on the opposite side of the conveyor. From wood fibres that are manufactured into paper and glass to metal materials which are melted and formed, ACI waste separation fans are compatible in various applications used in the recycling industry.\nAdditionally air knives can be employed during the separation of aluminium from non-conductive materials. Their purpose is to boost the flight of the conductive aluminium as it is ejected by the electric field created by the eddy current device (positives repelling each other) beyond a separating baffle. This greater distance of travel ensures a more positive separation of materials to achieve a cleaner end product.\nBlowers are commonly used to separate lights within recycling processes", "pred_label": "__label__POS", "pred_score_pos": 0.935012936592102}
{"content": "\"as His divine power has given to us all things that pertain to life and godliness, through the knowledge of Him who called us by glory and virtue...\" (2 Peter 1:3) (Ephesians 1:3) \"Blessed be the God and Father of our Lord Jesus Christ, who has blessed us with every spiritual blessing in the heavenly places in Christ\" (1 Corinthians 3:21) \"Therefore let no one boast in men. For all things are yours...\" God has given you everything you require to live victoriously and be successful in life. Meanwhile, in our opening verse, we see something very important: it's about your knowledge of Him. There's nothing you could ever need or desire for a godly life that's not already yours in Christ. However, making it a reality in your life is a function of your knowledge of Him.\nThis kind of knowledge is full, exact knowledge (\n\"epignosis\" in the Greek). God's provisions aren't going to come to pass in your life because they're written in the pages of the Bible. There's a knowledge of Him that you must have-- knowledge that unites the knower with that which is known-- knowledge that's beyond the senses, knowledge that's specific and without assumptions.\nSomething so beautiful and powerful about knowing Him is that not only do you get to know and appropriate all that He's given to you, you also get to know yourself.\nThe more you know Him, the more you know you. He mirrors you. His Word mirrors you. In Him, you see you. You can never really know yourself as God knows you until you know Him. He made you! Only He knows what's inside you and what you're capable, only He can reveal who you are to you.\nThe way to get to know Him, and to discover yourself, is to study and meditate on the Word.\n(2 Corinthians 3:18) \"But we all, seeing the glory of the Lord with unveiled faces, as in a mirror, are being transformed into the same image from glory to glory by the Spirit of the Lord.\" Search and discover who you really are by looking into the mirror of God by getting to know the Lord. The moment you get a hold of what the Word says is yours, or who the Word says you are, respond by affirming accordingly. That's how you endorse His Word into manifestation in your life. Prayer: Dear Father, thank you for giving me everything I need for a godly life of success and victory in this world. I'm full and loaded with blessings. As I look into your Word, I'm transfigured. You're glory is revealed in and through me, in Jesus' Name. Amen. Further Study: Philippians 3:10; John 10:15", "pred_label": "__label__POS", "pred_score_pos": 0.6180879473686218}
{"content": "How we influence far and wide Corporate Dojo's distinctive philosophies and approach to enhancing people leadership regularly attracts the attention of key media outlets seeking an expert opinion. Here are just some of them: How to get the hiring process right\nEmploying the wrong person can make a leader's job harder and affect a team's productivity. Here are seven tips to ensure you make the right choice.\nReflect for a moment on when you have made hiring mistakes. What were the consequences of bringing the wrong person or people into your team? If you get hiring decisions wrong, your job is made significantly harder as you fix challenges created by poor behaviours or bridge gaps due to inadequate capability.\nHiring the right person starts with a commitment to selecting candidates who are clearly aligned with your organisation's values. If a candidate's thinking and approach have a detrimental effect on the spirit, engagement or performance of the rest of your team, hiring them comes at a big cost. Be disciplined and patient as you search for the right person who brings the character traits that will enable them and your team to thrive.\nHere are seven tips to help you get the hiring process right:\n1. Ask the right questions\n2. Use collective wisdom\n3. Assess a candidate's career aspirations\n4. Look beyond your interview\n5. Reverse the reference check process\n6. Be diligent about probation\n7. Fail fast", "pred_label": "__label__POS", "pred_score_pos": 0.8423736095428467}
{"content": "Abstract : Neurons receive a large number of active synaptic inputs from their many presynaptic partners across their dendritic tree. However, little is known about how the strengths of individual synapses are controlled in balance with other synapses to effectively encode information while maintaining network homeostasis. This is in part due to the difficulty in assessing the activity of individual synapses with identified afferent and efferent connections for a synapse population in the brain. Here, to gain insights into the basic cellular rules that drive the activity-dependent spatial distribution of pre- and postsynaptic strengths across incoming axons and dendrites, we combine patch-clamp recordings with live-cell imaging of hippocampal pyramidal neurons in dissociated cultures and organotypic slices. Under basal conditions, both pre- and postsynaptic strengths cluster on single dendritic branches according to the identity of the presynaptic neurons, thus highlighting the ability of single dendritic branches to exhibit input specificity. Stimulating a single presynaptic neuron induces input-specific and dendritic branchwise spatial clustering of presynaptic strengths, which accompanies a widespread multiplicative scaling of postsynaptic strengths in dissociated cultures and heterosynaptic plasticity at distant synapses in organotypic slices. Our study provides evidence for a potential homeostatic mechanism by which the rapid changes in global or distant postsynaptic strengths compensate for input-specific presynaptic plasticity.", "pred_label": "__label__POS", "pred_score_pos": 0.7939847707748413}
{"content": "Situations that call for crisis communications can be stressful, complex and on-going. Those factors make this a vital time for an organization and its brand; and the right message can make the difference to the health of your image and reputation.\nAs organizations become more proactive in their continuity planning, many have embraced the role of communications in their preparation. These groups have also come to understand that fully managing a situation includes a solid crisis communications strategy as a vital part of the process. As professional communicators work on such events, one of the top decisions they’ll help you make will be picking your spokesperson.\nSelecting an appropriate spokesperson for a crisis situation is not always cut-and-dry. During a major event, you want to have the right spokesperson for the situation.\nHere are a few things to consider when choosing a crisis spokeperson: Organizational structure:Think about the way your organization is structured. Is it a smaller, tight-knit family business? Or is it a large organization with multiple layers? As a general rule of thumb, the larger the organization, the more options you’ll have. Proper level:Each issue that an organization faces has different levels of scrutiny. The specific situation will help you to determine the spokesperson based upon their perceived status. You can potentially diffuse or enflame a situation by selecting the correct or incorrect representative for the situation. Credibility:When selecting a spokesperson for a situation, your crisis communications team should consider an individual’s subject matter expertise. Your first inclination may be an adept speaker however, if he or she knows very little about the topic, you may want to reconsider. An expert will not only be more credible with content, but will also be better able to handle follow-up or unplanned questions. Escalation:In a situation, you should be mindful of a worst-case scenario. Information or events can change, putting your organization’s credibility at further risk. You should always consider giving your organization the potential to change or elevate your spokesperson if necessary.\nSelecting a spokesperson in a crisis communications situation is often multi-faceted decision. It is strongly encouraged that organizations build these considerations into their crisis communications plan to remove stress and demonstrate internal transparency as to why you’ve chosen a specific spokesperson instead of others.\nSituations which require crisis communications can be stressful and demanding. That’s why having a solid plan with defined roles in place prior to a situation can remove stress and be the difference between success and failure during a high-profile event.\n______________\nJeff Christensen serves as M3’s Client Communications Advisor. He has worked with organizations to help them plan for and handle crisis communications for the past fifteen years.", "pred_label": "__label__POS", "pred_score_pos": 0.5651713609695435}
{"content": "Xarelto (rivaroxaban) is prescribed for the treatment or prevention of blood clots. Xarelto is a blood thinner that can also be used for the treatment of deep vein thrombosis and atrial fibrillation. There is currently no generic version of Xarelto available in the United States or at PharmacyChecker-accredited online pharmacies.\nPeople can easily save money on Xarelto 15 mg by comparing Xarelto prices at Canadian and international online pharmacies with discount prices available at U.S. pharmacies in your neighborhood. Xarelto sold in the U.S. is manufactured in Germany or the U.S. (Puerto Rico).\nThe total price includes shipping fees which typically cover an entire order, making it more economical to purchase multiple medications in the same order.\nU.S. government officials have stated that individuals who order non-controlled prescription drugs from Canada or other foreign sources (up to a three-month supply) for their own use are not being pursued or prosecuted - although it is technically not legal for individuals to import most prescription drugs. The U.S FDA regulates the safety and efficacy of medications sold in U.S. pharmacies. Medications dispensed from outside the U.S. are regulated for safety and efficacy by pharmaceutical/pharmacy regulatory authorities in other countries. Read how regulations may differ by country.", "pred_label": "__label__POS", "pred_score_pos": 0.884293794631958}
{"content": "Many people become interested in edibles because they don’t enjoy the harsh experience of smoking or are worried about the long-term health concerns associated with it. Vaporization is another health-conscious alternative commonly recommended, but edibles can oftentimes provide longer-lasting relief to chronic symptoms like pain, often making them a preferred choice for medical patients.\nEach Laughing Monkey Edibles Bag Contains:\n6 PC\n150 MG Total 25MG Per Piece", "pred_label": "__label__POS", "pred_score_pos": 0.9975067973136902}
{"content": "Circumcision: Benign Physical Findings\nDuring the assessment of a newborn whose parents have requested circumcision, the examiner often encounters findings that, although not dangerous, cause concern or questions.\nMany of these findings are benign and do not present a contraindication to circumcision, but any finding in the perineal area should be thoroughly assessed before the procedure is considered.", "pred_label": "__label__POS", "pred_score_pos": 0.8141294717788696}
{"content": "Marine strategy framework directive: Defining joint monitoring opportunities for the Eastern Mediterranean and the Black Sea, through dedicated decision making workshops and innovative policy tools [in Marine Policy] Marine Policy, Volume 67, May 2016, Pages 76–82\nAbstract:\nThe Marine Strategy Framework Directive (MSFD) is an important milestone for the preservation of the European marine environment. However, Member States can find its monitoring requirements challenging, particularly where it regards the definition and implementation of joint monitoring programmes between neighbouring countries. The challenges are even greater in the Mediterranean and the Black Sea, where many countries are not members of the European Union and where Regional Sea Conventions face greater difficulties in coordinating monitoring activities. This paper presents the results from two regional workshops, within the framework of IRIS-SES project, which aimed to inform policy- and decision-makers in the Eastern Mediterranean and the Black Sea on what key stakeholders, including scientists, academia and local authorities, consider the main gaps, needs and opportunities for the MSFD joint monitoring regarding eutrophication and contaminants. It shows that a bottom-up approach, guided by structured workshops, can be a successful means of enhancing cooperation.\nClick on the image below to access the full paper.", "pred_label": "__label__POS", "pred_score_pos": 0.9448084831237793}
{"content": "At the time, Mullis was manually synthesizing oligonucleotide probes to help detect a sickle cell anemia mutation. He had grown tired of the laborious, error-prone manual approaches required to amplify and detect target genes and was contemplating ways to ease the mundanity of his work. In what has been described as an “ah ha!” moment in his silver Honda Civic, Mullis conceived of a method that relied on a cascading biochemical reaction that split (denatured) target DNA segments, which would then be combined (annealed) with complementary primers and then enzymatically processed by a DNA polymerase to create new DNA templates (this cascading reaction resulting in polymerized target DNA become known as a “Polymerase Chain Reaction” or “PCR”).", "pred_label": "__label__POS", "pred_score_pos": 0.7151730060577393}
{"content": "Regardless of what industry you work in, one thing that you likely know well is that your peers, acquaintances, and clients may not always agree with you. With so many different people and unique minds in the world, it’s unfathomable to imagine that everyone will agree and get along. With this in mind, an essential skill in the realm of business is dispute resolution.\nThis entails defusing a tense situation between two parties, understanding their problems, and finding a solution that is appropriate for the situation.\nBusiness disputes are a regular occurrence and it’s only a matter of time before you face one yourself. How you respond will have a significant impact on the outcome, your relationship with the other party, and your reputation.\nTo ensure that you know your options when handling a business dispute, we’ll explain the primary methods used to manage disagreements below.\nMediation: A relaxed approach.\nThe most relaxed approach to dispute resolution is mediation. This is the most informal style and works best for basic misunderstandings. A good example of this would be figuring out how much you and another party should pay for a minor accident that you both contributed toward.\nWith mediation, there’s an understanding that you want to continue a healthy working relationship with the other party.\nHowever, there are clear differences and it’s difficult to see who is right and what is fair.\nMediation involves a third party known as a mediator. This person will listen to both sides of the story and facilitate discussions between you.\nA mediator is fantastic for helping guide you to a common ground. They do not decide for you, nor can they force you to follow through with the decision you agree upon.\nThis is typically the first step in resolving business disputes. If you can’t work things out with another party through mediation, then you’ll need to escalate the formality level.\nArbitration: A less formal approach.\nTaking things a step further, you can use arbitration to resolve a dispute.\nArbitration is much more formal than mediation, making it ideal for situations with conflicts of interest and politics. There is often less of a concern on maintaining a relationship with the other party and more of a focus on being on the favorable end of the outcome.\nWhen pursuing arbitration, a third party is also involved. The key difference here is that this third party is an authority figure. This means that they will make the decision, which will be binding. You and the other party will submit your case, including any relevant evidence. The arbitrator will serve as a judge and pass a sentence that is often unappealable.\nWhile arbitration is similar to litigation, arbitration is far quicker and a more private process. This makes it a great choice for businesses looking to maintain their reputation.\nLitigation: A more formal approach.\nShould you require legal intervention, litigation will be the method employed.\nThis is often the most expensive, draining, and time-consuming way to handle a dispute. It is the most formal strategy and involves the court system.\nLike arbitration, litigation seeks to find a ruling on the situation. It’s typically reserved for fairly hostile situations that cannot be managed with less formal styles of dispute resolution.\nLitigation involves a third party serving as a judge. Additionally, a jury panel will also sit in and listen to the case. Both parties will collectively pass a judgment, which often makes the ruling impartial. Court cases take several months and even years to complete. Between scheduling appearance dates, gathering, submitting, and reviewing evidence, listening to testimonies, and managing delays, there’s a lot to work through and it will inevitably take time.\nYou should always aim to avoid using litigation whenever possible. Other dispute resolution techniques are often cleaner, easier, cheaper, and less stressful to deal with.\nMixed strategies: A combined approach.\nThe three methods mentioned above are the main techniques used to resolve business disputes. They vary in severity, how the issue is approached, and how enforceable the outcome is. While these three set the standard for business disputes, several mixed strategies exist that use a combination of mediation, arbitration, and litigation.\nA few of them include a minitrial, summary jury trial, renting a judge, and negotiations. While not all strategies are effective for every situation, it’s smart to try whatever you can to keep a dispute out of court, so no one wastes their time and money on an easy resolvable case.\nMediation and arbitration are not always successful, but litigation is often unappealing. This is why mixed strategies have been created to help offer more opportunities to quell a dispute.\nConsider your unique situation and what it requires for resolution. Find a strategy that suits your situation well for a quick and painless solution.\nClosing thoughts\nBusiness disputes are a normal part of operating a business. Misunderstandings and mistakes are easy to make, but sometimes disagreements require a third party for resolution.\nBecause of this, you should understand what the main strategies for business dispute resolution are. This includes mediation, arbitration, litigation, and techniques that are some combination of the three or several mixed strategies.\nWhile disputes are certainly a hassle, they don’t need to be a big deal. If you’re prepared to handle any disagreement that comes your way, any misunderstands that happen in the future will be easily squashed and everyone can happily return back to their work.", "pred_label": "__label__POS", "pred_score_pos": 0.5669776201248169}
{"content": "On August 3, 2020, the CFTC issued a Consent Order imposing a $4 million civil penalty and permanent injunctions against the New York Mercantile Exchange, Inc. (“NYMEX”) and two NYMEX employees, William Byrnes and Christopher Curtin, for disclosing confidential information about futures trading activity in the possession of NYMEX to commodities brokers.\n1 The Consent Order demonstrates the CFTC’s continued emphasis on investigating and pursuing insider trading activity and holding exchanges accountable for their employees’ conduct. NYMEX Employees’ Insider Trading\nOn numerous occasions between 2008 and 2010, Byrnes and Curtin were found to have disclosed to a broker material nonpublic trade information obtained through Byrnes and Curtin’s special access as NYMEX employees. Byrnes and Curtin disclosed the following confidential information: the identities of counterparties to specific options trades; whether a counterparty purchased or sold an option; whether the option was a call or put; the volume of contracts traded; the expiry; the strike price; and the trade price. According to the Consent Order, this conduct violated Section 9(e)(1) of the Commodity Exchange Act (the “Act”), which prohibits insider trading, and CFTC Regulation 1.59(d)(1)(ii), which prohibits disclosure of material nonpublic information obtained through special access as an employee of a self-regulatory organization. Section 9(e)(1) and CFTC Regulation 1.59(d)(1)(ii) are specific to “registered entities” such as contract markets, clearing organizations, and swap data repositories, but does not apply to market participants. Accordingly, this action was not based upon the CFTC’s fraud-based manipulation authority.\nIn addition to imposing a monetary penalty, the CFTC imposed permanent trading bans on Byrnes and Curtin. Curtin voluntarily resigned from NYMEX in April 2009, and Byrnes was terminated in December 2010. Given that the relevant activity occurred between 2008 and 2010, it is likely that the defendants entered into an agreement tolling the statute of limitations during the investigation. The CFTC also charged Ron Eibschutz, the broker who received the nonpublic information, with aiding and abetting the NYMEX employees’ violations of the Act. The August 3, 2020 Consent Order does not resolve the CFTC’s claim against Eibschutz.\nNYMEX Found Vicariously Liable\nThe Consent Order holds NYMEX vicariously liable for the actions of Byrnes and Curtin, imposing a $4 million civil monetary penalty jointly and severally on NYMEX, Byrnes, and Curtin, with the liability of the individual traders capped at $500,000 in total. Additionally, the CFTC enjoined NYMEX from further violations of Section 9(e)(1) of the Act and CFTC Regulation 1.59(d)(1)(ii).\nThis enforcement action against NYMEX is the “first time the CFTC has charged an exchange with violations of the proscription in the Act and the CFTC regulations against disclosures of material nonpublic information by exchange employees.”\n2 Director of Enforcement James McDonald emphasized that “commodity exchanges are responsible for violations of the Act or CFTC regulations by their officials, employees, and agents within the scope of their employment or office.” 3 This serves as a reminder that exchanges must take affirmative steps to ensure that their employees fully understand their obligations under the Act and the CFTC rules. ******\nIf you have any questions regarding this client alert, please contact one of the authors, any member of our CFTC team listed below, or the Willkie attorney with whom you regularly work.\nClick here to download this article.\n1 CFTC v. William Byrnes, Christopher Curtin, NYMEX, and Ron Eibschutz, No. 13 Civ. 1174 (VSB) (Aug. 3, 2020). 2 Commodity Futures Trading Commission, NYMEX and Two Former Employees to Pay $4 Million for Disclosing Material Non-Public Information (Aug. 4, 2020), here. 3 Id.", "pred_label": "__label__POS", "pred_score_pos": 0.6318154335021973}
{"content": "An observational cohort study with a large number of patients was conducted to compare the clinical outcomes of treatment with first-generation autologous chondrocyte implantation to that of treatment with autologous bone marrow stem cells. Seventy-two matched (lesion site and age) patients underwent cartilage repair using chondrocytes or bone marrow stem cells. There was a significant improvement in the patients quality of life after cartilage repair in both groups. However, there is no difference between the two groups in terms of clinical outcomes. The authors concluded that bone marrow stem cells are as effective as chondrocytes for articular cartilage repair, and have advantages in terms of requiring less knee surgery, reduced costs, and minimised donor-site morbidity (Nejadnik et al., 2010)", "pred_label": "__label__POS", "pred_score_pos": 0.5829900503158569}
{"content": "Carpet beetles are incapable of biting a human in any perceptible way. Their mandibles are not large enough to inflict a painful bite and they carry no venom. Due to this there are virtually no health concerns from being bit by a carpet beetle.\nHowever, there are potential health concerns when the beetles gain access to human foods. Cross-contamination can become a big risk in these food situations and this should be taken seriously.\nWith Halloween just around the corner, its time for larger-than-life creepy, crawly creatures skittering across lawns, lurking in dark alleyways and dropping out of nowhere to frighten their hapless victims.", "pred_label": "__label__POS", "pred_score_pos": 0.8725265264511108}
{"content": "As a pediatrician, I often treat kids that are “Neonatal Intensive Care Unit (NICU) grads”, which refers to babies that needed NICU care after birth due to prematurity or other life-threatening medical conditions. I’m always inspired by these patients and their families because they have persevered through very challenging experiences.\nProject Sweet Peas is a 501(c)3 national non-profit organization coordinated by volunteers, who through personal experience have become passionate about providing support to families of premature or sick infants and those who have been affected by pregnancy and infant loss. This amazing organization acknowledges the importance of parental involvement in the NICU, and seeks to promote family-centered care (FCC) competencies in hospitals nationwide. Care packages, hospital events, peer-to-peer support, financial aid, educational materials, and other Project Sweet Peas services, support the cultural, spiritual, emotional, and financial needs of families as they endure life in the NICU.\nProject Sweet Peas also makes a lifelong commitment to support families experiencing pregnancy and infant loss. In a baby’s last moments, families are encouraged to make cherished memories with custom Project Sweet Peas keepsake items. Healing and remembrance continue to be fostered through programming such as peer-to-peer support, and their annual candlelight vigil.\nI’m so impressed by the wonderful work Project Sweet Peas is doing for so many families and babies, as well as their mission and values. The support they provide to families of fragile infants and the way they inspire them with the hope of tomorrow really touches this mama’s heart.\nDr. Sylma is committed to supporting Project Sweet Peas with a portion of our sales. Please join us in supporting these families who have had their world turned upside down and are experiencing tremendous difficulty in bringing their children into health, and also those who tragically have lost their little ones. Together, we can truly serve these families in need.\nLove always,", "pred_label": "__label__POS", "pred_score_pos": 0.7484703063964844}
{"content": "EVENT SUMMARY\nWhen it comes to developing a pragmatic infrastructure and cloud strategy, there are key areas to address: How do you shift from legacy systems to embrace future needs? How do you design for uncertainty? What cloud strategies and options should you consider?\nGartner Analyst, David J. Cappuccio, Chief of Research for Infrastructure, responsible for research in enterprise data center strategies and trends, data center cloud and hybrid strategies and data center consolidation and migration strategies answers these key questions and shares emerging infrastructure trends and strategies.\nRichard Zheng, President of Servpac, a local Telecom and IT solutions provider, also shares trends he sees in Hawaii business’ adoption of the cloud and how flexibility is a key component to designing a strategy. He shares how he leverages expertise from Gartner as he prepares his organization to meet the changing needs of customers.", "pred_label": "__label__POS", "pred_score_pos": 0.7806519865989685}
{"content": "Overtime Wage Claims Under The Fair Labor Standards Act And Indiana Law Overtime Wage Claims Under The Fair Labor Standards Act And Indiana Law\nMany American’s live paycheck to paycheck, making untimely or improper payment a burden for many workers. Employees may hesitate, however, to challenge their employer and assert their right to be paid the amount they have earned.\nThe Fair Labor Standards Act (FLSA) and other applicable state law protect an employee’s right to timely and correct payment of overtime hours.\nFair Labor Standards Act: Overtime Pay\nThe U.S. Wage and Hour Division of the Department of Labor (USDOL) specify that any employee covered by the FLSA must receive overtime pay for any hour worked over 40. Additionally, the rate of overtime pay must be at least 1.5 times the employee’s regular base pay. These rules do not apply to weekend or holiday hours, however, which may remain at an employee’s standard rate.\nOccasionally an employee is hired to work more than 40 hours per week. The FLSA has provisions to ensure fair overtime payment for these situations as well. This ensures employers cannot avoid paying overtime based upon an employee’s contract.\nFLSA Vs. Indiana Wage Claims Act\nFor those individuals not covered by the FLSA, it is possible to have a claim arise under the Indiana Wage Claims Act (Act). This Act allows employees who have received less compensation than they are owed, or have not received their compensation on time, to receive back-wages, as well as penalty damages and attorney fees.\nThe Indiana Department of Labor (IDOL) limits these claims and states that the maximum amount a claim arising under the Act may be $6,000. Any amount exceeding this limit should be brought to the attention of a private attorney to determine how to proceed.\nCollecting Wages Owed\nIf anyone has questions about the FLSA or the Act they should contact an experienced employment law attorney. An attorney can help determine your eligibility and the viability of a potential claim.\nFinally, not receiving the proper income or not receiving it on time can be a very time-sensitive dilemma. Families need to pay their mortgage, their phone bill, and put food on the table. While the USDOL and IDOL do their best to resolve wage disputes as quickly as possible, it is recommended an employee consult an attorney to ensure all procedures are followed correctly and promptly.", "pred_label": "__label__POS", "pred_score_pos": 0.679132342338562}
{"content": "Pierpaolo Polzonetti\nThis article explores how food and drink in opera convey meaning, define relationships, trigger psychophysical reactions, and denote dramatis and singers’ personae. It proposes a basic theoretical foundation of “operatic gastromusicology” by outlining five primary functions of food in opera: social, intimate, denotative, medicinal, and dietary. These five functions are exemplified through the analysis of gastronomic signs in Verdi’s\nTraviata. The opera and its performance history illustrate how the production of this opera reflects the changing culture of food and the body. Luchino Visconti’s production in Milan’s La Scala in 1955, with Maria Callas as the consumptive protagonist, was in this respect a watershed in the history of opera. The singer’s rapid and prodigious weight loss prior to this performance triggered an epochal shift in opera culture toward an unprecedented conflation of the dramatis and singer’s persona. Linda Hutcheon and Michael Hutcheon\nThe singing and acting performer in staged opera\nhas and also performs a body that is both a biological entity and an ideological construct: its race, sex, physique, and age are all given meaning by directors—and audiences. Within the contexts of feminist, queer, and disability studies, this chapter reads the “marked” body of the protagonist of David Alden’s 2008 production of Gaetano Donizetti’s 1835 Lucia di Lammermoor as the literal embodiment of the excruciating vulnerability of Lucia as subject through the medium of her youthfulness and her mixed race: a Down syndrome child sexually abused by her brother on stage. Just as the opera’s use of coloratura is a marked musical gesture of madness in dramaturgical terms for the “voice in performance,” so the specifically marked corporeal body of Lucia was crucial to this production’s dramatic power, as well as the ethical and political issues it raised. Hanne Blank\nThis chapter proposes that in the grand opera of the nineteenth century, sexuality and dis/ability combine with opera’s musical, literary, and dramatic elements, enabling experiences of the sublime within the context of human embodiment. Operatic representation of disability, including madness and lovesickness, enables audiences to both experience and contemplate uncontrollable and overwhelming forces, the essence of Arthur Schopenhauer’s conception of sublimity. The rise of these representations in nineteenth-century opera coincides with increasingly influential concepts of normative bodies, bodily controllability, and marginalization of bodily excess and disability. Opera’s textual, musical, sung, and acted representations of embodied excess, disability, and physical extremity enhance audiences’ immersive witnessing of and physical empathy with those representations.", "pred_label": "__label__POS", "pred_score_pos": 0.5476253032684326}
{"content": "Long-term kidney allograft survival remains a major clinical challenge. Recurrent glomerulonephritis disease, including recurrence of IgA nephropathy (IgAN), is a significant barrier to long-term kidney allograft survival. We performed a retrospective, observational study to evaluate the role of everolimus (EVR) in the risk of recurrent IgAN.\nThe study included data from 135 patients aged ≥16 years with biopsy-proven IgAN on native kidneys who underwent a kidney transplant (KT) between December 2002 and December 2018. Patients who underwent de novo KT received mycophenolate mofetil (MMF) (n = 107) or EVR (n = 28). The mean recipient age in the MMF and EVR groups was 44.9 ± 13.7 and 41.1 ± 10.1, respectively. The median (interquartile range) follow-up period was 90.9 (64.9-115.3) and 21.2 (11.4-30.6) months, respectively (< .0001). All patients received continuous corticosteroid and tacrolimus therapy. The death-censored graft survival rate after KT and the recurrence-free survival rate did not differ significantly between the groups. Univariate and multivariate Cox regression analyses identified EVR for de novo KT as an independent predictive factor for recurrence-free survival (P = .024). Our findings suggest that EVR-based regimens with tacrolimus and corticosteroid therapy for de novo KT reduce the recurrence of IgAN compared with MMF-based regimens with tacrolimus and corticosteroid therapy. Copyright © 2020. Published by Elsevier Inc. References\nPubMed", "pred_label": "__label__POS", "pred_score_pos": 0.9278544187545776}
{"content": "Despite stereotypes to the contrary, others have discovered and are promoting the inspiring stories & messages freely given by our elders.\nGail Zugerman offers up these stories through her podcast - GrowingOlderWithGusto. In this episode, Gail and Lee compare notes about their experiences with the older generations and what they have learned from this engagement. Together they explore lessons such as how successfully aging people view their past & future and how to turn an ordinary past into an extraordinary future. You won't want to miss Gail's 5 keys that are critical for successful aging. This conversation will surely inspire an upgrade in your thinking as to how you see yourself on your forward path.\nDespite stereotypes to the contrary, others have discovered and are promoting the inspiring stories & messages freely given by our elders.\nLee Deeply respects the wisdom and perspectives of the elders in our culture. The changes they have seen in their lifetime often provide useful insights about what lies at the heart of many of our current events. In this episode, Lee has the opportunity to speak with 94-year-old elder - Priscilla. They discuss the culture and society as it was and how it has evolved to the characteristics around us today. Priscilla points to many cultural factors such as the elimination of Sunday Blue laws, the introduction of factories, World war 2 and the Vietnam War, and the rise of social media as a cultural influence. She also muses on the many pursuits she has engaged in during her time - piano, painting, Tai-chi. Her ability to speed read helps her to stay cognitively sharp and up-to-date on current events. Join Lee in this intriguing conversation with an engaging elder to see where your insights will fall.\nJoin Lee as he continues to share his insights and experiences in handling the challenges of aging. In this episode, he shares the difficulties of going blind in one eye. Aging forces us to accept who we are becoming. The question is: How are we dealing with those challenges? Are we sidelined by them, or do we choose to see these as opportunities to learn more about ourselves and the possibilities that our inevitable aging bring? Lee goes into his personal history in facing medical trauma, knowing that the master is not the one who has the best circumstance, but one who makes the best from any circumstance. Lee firmly believes that you cannot have bad without good. They are flip sides of the same coin. As he promised, Lee allows his listeners and Insider’s Club members to follow along with his aging journey as he explores these somber adventures with acute glaucoma and blindness in his right eye.\nLee is back to explore how our thoughts evolve with us. More specifically, this episode discusses the human value system and how it typically changes with the years. Human values are the virtues that guide us to take into account the human element when we interact with other human beings. They determine how we feel and treat others on a small and large scale. These values help us to determine what is right or wrong in our lives. Lee has observed that our values (e.g. Achievement, Hedonism, Security, Conformity, Tradition, Power, etc.) changes as we age. He offers 4 introspective questions whose answers reveal who you were, as well as who you have become in relation to your values. He also shares his own answers to these questions to show the changes that have occurred in his thinking over the past 25 years. Listen and join Lee in a powerful tool to help you forgive your past and chart a brighter future.\nLee's guest for this episode is Dr. Rachna Patel, whose practice has given her the reputation of being the Medical Marijuana Expert. Together, they bring this controversial topic into the light to answer many common questions (and a few uncommon ones). The conversation is packed with information such as - Medical vs. Recreational; the medical conditions that can be directly addressed with these treatments; who should avoid medical marijuana; Big Pharma's role, plus much more.\nThe challenges of aging is something most of us are not yet familiar with. But we will all face these challenges. And who will teach us how to see and approach these difficulties (or pleasures) of getting older. This episode introduces \"the Aging Academy\" where Lee offers to become a \"pioneer for aging\" by exposing his personal challenges that affect him as the years mount up. Lee, like everyone else, is getting older. Increasing stress, shifting priorities, aching bones, and changing social patterns all have their impact, and Lee wants to share with you, through the Aging Academy, how he is (or is not) dealing with these issues in his life. Lee talks about his anticipation and expectation for the Aging Academy project to be a source of specific information on tackling common problems of aging in our culture", "pred_label": "__label__POS", "pred_score_pos": 0.5233064889907837}
{"content": "The total area of Queensland that is drought-declared has risen to 65.2 per cent after a significant lack of rainfall across central, southern and south east Queensland.\nAgriculture Minister Mark Furner has accepted the recommendations of local drought committees following their assessment of seasonal conditions and drought declared five additional shires and extended or issued part drought declarations in four others.\nThe new declarations cover Ipswich Regional Council, the remainder of Western Downs Regional Council, Scenic Rim Regional Council, the remainder of Banana Regional Council, Gladstone Regional Council, Rockhampton Regional Council, Livingstone Shire and the southern portion of the Central Highlands Regional Council including part of the Woorabinda Aboriginal Shire Council area, defined as south of the Capricorn Highway.\nAny producer who is experiencing difficult conditions in any council area that is not drought declared, that they can apply for an Individually Droughted Property (IDP) declaration giving them the same access to drought assistance as an area declaration.\nProducers can access further information at longpaddock.qld.gov.au.\nFor further information on drought assistance visit daf.qld.gov.au or call the Customer Service Centre on 13 25 23.", "pred_label": "__label__POS", "pred_score_pos": 0.5904095768928528}
{"content": "Over the last few years, the global iGaming industry has reached new, unprecedented heights. In turn, this has resulted in contemporary gamers exploring a wide array of diverse, casino-oriented markets. Intriguingly, this shift in user trends has been indicative of the ever-changing nature of the sector.\nWhile the emergence of online casinos has proved fruitful to numerous countries, the market’s growth has highlighted the influence of Malta regarding digital gambling. Fundamentally, the Southern European island country’s existing gaming outlook is a reflection of broader alterations. So, let’s consider Malta’s approach to in-house and online gaming.\nAnalyzing Malta’s Land-Based Offerings\nRecently, increasing numbers of casino players have sought to explore numerous offerings available at digital operators. Primarily, this is a result of the accessibility, convenience, and variation that comes with web-based platforms. Despite that, in-house opportunities remain a focal point of the country’s in-house entertainment.\nAlthough there is little choice available to those seeking a land-based casino experience, with VisitMalta listing four establishments that provide traditional offerings, the scale of each illustrates their local appeal. Of those available, Casino Malta by Olympic Casino is the country’s largest, with its opportunities covering poker, table games, and 300 video machines. Since opening in 2015, the facility is considered to be Malta’s best casino because of its diverse approach to in-house entertainment.\nHowever, despite the popularity of land-based casinos, the emergence of digital alternatives has enabled Malta to explore varied approaches to contemporary betting. In this regard, it’s apparent that the country is something of a microcosm of global trends. As per Malta InsideOut, slot machines generally take a backseat compared to roulette, for example, which is the island country’s most popular game. Interestingly, this is somewhat similar to the United Kingdom. Of all the activities, a Gambling Commission report states that sports betting is participated in the most, as opposed to slots.\nDiversifying to Become an Industry Leader\nWhile land-based establishments have yet to allow Malta to explore the development of in-house slots, digital alternatives have proved to be undeniably beneficial. Contrary to Malta’s limited real-world casinos, the country boasts a significant presence within the iGaming sector. Crucially, the Malta Gaming Authority regulates one of the country’s major economic contributors in the form of both in-house and digital casinos.\nBecause of the sector’s well-regulated nature, Malta has become the industry’s leading figure, morphing itself into the world’s iGaming capital. To showcase this, a whole host of contemporary operators are licensed by the MGA, including Caxino. The platform itself offers prospective players a whole host of gaming opportunities, such as live variants, table games, and slots, such as Aztec Gems Deluxe and Deadwood.\nInterestingly, this showcases how the country’s influence has enabled it to explore aspects of the casino industry that have yet to hit the heights at land-based facilities. With slots now becoming a central part of iGaming, Malta’s influence could aid in enhancing the appeal of machine games across the world.\nIn a Position to Bring About Change\nDigitally, Malta is a dominant player in the world of casino gaming. While it remains to be seen if this leading status will impact real-world slot popularity, few can argue that it won’t have any negative implications on participation. In becoming a central figure in the iGaming industry, it appears apparent that local gaming trends in Malta are mirrored by players across the globe, hence the need for well-regulated operators.", "pred_label": "__label__POS", "pred_score_pos": 0.8100011348724365}
{"content": "Abstract\nDrawing on institutional theory, this study examines how adherence to a number of 'institutional' and 'technical' environmental forces can influence the business success of managed cam organizations (MCOs). The standards studied include: (1) institutional forces: socially accepted procedures for delivering care (access to quality care, availability of information, and delivery of care in a personal manner); and (2) technical forces: industry standards for cost control and efficient use of financial and medical resources. The most significant finding is that successful MCOs must conform to both institutional and technical forces to be successful. MCOs that conform to either one or the other type of standard were no more successful than those that conformed to neither. These findings have several important implications for MCO strategy. First, to be successful, MCO executives must understand the external environment in which they operate. They must anticipate and respond to shifts in that environment. Second, this understanding of the external environment must place equal emphasis on societal demands (e.g., for accessible care and information) and on technical demands (e.g., for cost-efficient care). These findings may well reflect that once managed care penetration reaches relatively high levels, marketshare can no longer be gained through cost-efficiency alone; rather, enrollee satisfaction based on societal demands becomes a key factor in maintaining and gaining marketshare. Institutional theory provides some strategies for accomplishing these goals. Cost-containment strategies include implementing policies for cutting costs in areas that do not affect the quality of care, such as using generic drugs and reducing administrative excesses and redundancies. At the same time, MCOs must implement strategies aimed at improving conformity to prevailing societal perceptions of appropriate care, including providing patients more freedom to choose their physicians and encouraging and rewarding care providers for being friendly and personable. An MCO should work to inform the public of the organization's efforts to provide high-quality, low-cost medical care in a friendly, convenient manner.\nASJC Scopus subject areas Leadership and Management Health Policy Strategy and Management", "pred_label": "__label__POS", "pred_score_pos": 0.5300046801567078}
{"content": "Reasons to Seek a PE Partner\nFor owners, the thought of making a business transition or adding a partner can be very stressful. However, working with a PE partner is often:\nAn ideal way to overcome succession challenges and provide ownership to management, family members or others The most viable method of expanding a business or acquiring a competitor A sound way for owners to realize liquidity while maintaining ownership — a win-win for those who believe in their company's future, but don’t want to face all of the risks alone The most direct path for a company to make fundamental business improvements that often are more difficult to achieve under current ownership constraints The most viable way to ensure your company isn’t left behind during an economic phase where many industries are experiencing consolidation", "pred_label": "__label__POS", "pred_score_pos": 0.9876635670661926}
{"content": "Abstract\nHER2 is overexpressed or gene amplified in 20%-25% of breast cancers. The anti-HER2 monoclonal antibody trastuzumab targets HER2-positive tumors, inhibiting proliferation and inducing cell death via extracellular and intracellular mechanisms. The clinical benefits observed with trastuzumab in the metastatic setting provided the rationale for assessing trastuzumab in the treatment of early breast cancer. Four large phase III adjuvant trials (NSABP B-31, NCCTG N9831, HERA, and BCIRG 006) investigated the efficacy and safety of 1 or 2 years of trastuzumab given in combination with or after standard adjuvant chemotherapy. The addition of 1 year of trastuzumab to adjuvant chemotherapy significantly improved disease-free survival (DFS) by 33%-52% and overall survival by 34%-41% in the 4 trials. The DFS benefits were observed regardless of age, nodal status, hormonal status, or tumor size in all trials. The cumulative incidence of congestive heart failure or cardiac death ranged from 0-0.9% in the control arms and 0-3.8% in the trastuzumab-containing arms. These were below the safety cutoff points set by the individual studies' independent data monitoring committees, indicating acceptable cardiac safety. Risk factors associated with cardiac dysfunction included baseline left ventricular ejection fraction level, hypertension, and older age. The addition of trastuzumab to adjuvant chemotherapy provides significant survival benefits with a positive benefit/risk ratio. Ongoing and planned trials correlated with basic science will enhance our understanding of HER2-positive disease, leading to treatment optimization and further improvements in patient outcomes.\nKeywords c-Myc Cardiac toxicity Chromosome 17 Paclitaxel Topoisomerase IIα ASJC Scopus subject areas Cancer Research Oncology", "pred_label": "__label__POS", "pred_score_pos": 0.5546635389328003}
{"content": "On 14 June 2016, Tania Molteni, guest speaker from the collaborative project COOPENERGY and researcher at Bocconi University in Italy joined the 3\nrd Partners’ Meeting of the multEE project in Sarajevo. Ms Molteni’s presence aimed to increase learning and exchange of experience between projects with a similar focus. During her talk, she addressed the importance of multi-level governance for sustainable development. She also presented a user guide on Multi-Level-Governance focusing on the coordination between the regional and local levels, which was created with the aim of developing sustainable energy concepts.\nThe COOPENERGY project was funded by the Intelligent Energy Europe Programme and aimed at supporting the development of more effective collaborative working between regional and local public authorities to maximise positive energy planning outcomes and accelerate reduction of greenhouse gas emissions.", "pred_label": "__label__POS", "pred_score_pos": 0.9582659602165222}
{"content": "New data from the Department of Health is showing a growing share of very young children and teenagers are testing positive for COVID-19 compared to earlier in the pandemic, a worrying sign that could have major implications for New York City’s in-person schooling initiative.\nCompared to other age groups, children aged 4 and under showed the highest weekly positivity rate: 3.2% for the week ending on October 31st, compared to 2.2% for city residents overall. The positivity rate was more than double that of the first week of September, when 1.4% of children under 4 tested positive.\nChildren ages 13 to 17 had the second highest weekly positivity rate. In early October, the rate among that group soared to 3.9% before declining to 2.6% in the last week of October.\nInterestingly, positivity rates for children aged between 5 to 12 also began rising after September, but after peaking at 2.8%, have since declined to 1.5%.", "pred_label": "__label__POS", "pred_score_pos": 0.6477899551391602}
{"content": "The \"gluten-free\" final rule, published by the U.S. Food and Drug Administration (FDA) in 2013, is intended to provide safe food choices for people suffering from celiac disease. This final rule is not applicable for cosmetic products. As a result, analytical methods for gluten estimation in cosmetics are warranted to aid in the determination of the presence of gluten in these products. A survey of 36 cosmetic products was conducted to measure gluten content by three different ELISAs. None of the nine gluten-free-labeled cosmetics included detectable gluten. The gluten content in six cosmetics was 15.2-1453.5 ppm by one competitive ELISA, whereas three cosmetics contained 11.7-572.3 ppm gluten when quantitated with two sandwich ELISAs. Gluten or hydrolyzed wheat protein was found as an ingredient in five cosmetics with detectable gluten levels. A poor recovery of gluten was observed for most of the cosmetics in the foundation/blush/powder category by ELISA kits. This finding warrants a need for improved analytical methods for gluten estimation in cosmetics.", "pred_label": "__label__POS", "pred_score_pos": 0.8809838891029358}
{"content": "If you’ve ever considered entering the trading market, you may have heard people dissuading you and telling you that it is a gamble. While they are not wholly wrong, they aren’t entirely right either. Sure, your luck plays a role in the outcome of your investment, but there are several additional factors and trading strategies you can leverage for a fruitful return on investment. Once you learn these trading strategies, you can master the art of market investments. Let’s find out what momentum trading is, and the critical factors involved in implementing strategies for it.\nWhat is momentum trading?\nMomentum trading is defined as the practice or act of buying and selling trading market assets, as per their recent price trend strengths. The practice assumes the premise that if enough force is applied to a price move, the price will continue moving in the same direction. Assets start attracting more attention from investors and traders upon reaching a higher price, which, in turn, pushes the price to higher heights. This trend continues until numerous sellers enter the market. Once there are enough sellers in the market, the momentum strategy is said to be in force, causing the momentum to change its direction, and forcing the asset’s price to reduce.\nHow do traders implement momentum trading strategies?\nMomentum traders attempt to identify the strength of a trend in a given direction. Once this happens, they open a position, hoping to gain from the expected change in the asset’s price. They then close the position when the trend begins losing its strength. Momentum traders primarily focus on the main body of the move of the price instead of attempting to find or analyse the top and bottom of a given trend. Their primary objective is to exploit the market sentiment and the herd mentality, i.e. the general tendency among traders to follow a proven concept and benefit from it.\nFactors involved in implementing a solid strategy\nThe momentum trading system is primarily based on three key factors, based on which strategies are implemented. They are as under\n1.\nThe volume of the assets traded\nIn terms of momentum stock trading, the volume is defined as the amount of the asset traded, in a specific time frame. It represents the total number of assets traded as opposed to the total number of transactions. As such, if ten buyers buy one asset each, it appears the same as if one buyer has bought ten of the same asset. Volume, in momentum trading, is rather crucial as traders should be able to take rapid entry and exit positions. The positions they take depends on the presence of a steady number of buyers and sellers. A market with a high number of traders is known as a liquid market, in which traders can easily exchange assets for cash. If there aren’t enough traders, the market is deemed illiquid.\n2.\nThe volatile market conditions\nIn the momentum trading system, traders consider volatility as their primary source of income. Volatility represents the degree to which an asset’s price changes. A highly volatile market represents the presence of a significant price swing, whereas low volatility means that the market is comparatively stable. In momentum trading, traders attempt to seek out volatile markets and take advantage of the rise and falls in the asset’s price in the short term. These traders attempt to capitalise on the volatility of the asset’s prices. Since volatility represents risks, momentum traders typically implement risk management strategies to protect their trades from the volatile market movements, including setting the stop-loss limits.\n3.\nThe timeframe of the trade\nThe final factor involved in implementing a water-tight strategy is the total time taken to enter and exit a trade. Most momentum trading strategies focus on short-term movements in asset prices. However, how long a trend lasts entirely depends on the duration taken by the trend to maintain its strength. The time frame strategy is ideal for traders who choose to employ a longer-term trading style, for instance, position trading. Short-term traders can also combine this strategy with other strategies such as scalping and day trading.\nFinal note:\nAs a market trader, you can always benefit from having multiple strategies up your sleeves. It would help if you also familiarise yourself with the various trading indicators such as the Momentum Indicator, the Relative Strength Index (RSI) Indicator, Moving Averages Indicator and the Stochastic Oscillator Indicator. You can also identify the assets you may be interested in investing and practice trading on various online simulators before you start trading live. For more details on momentum trading, you can contact an Angel Broking Expert.", "pred_label": "__label__POS", "pred_score_pos": 0.6278104782104492}
{"content": "Right ventricular (RV) function plays a pivotal prognostic role in multiple cardiac diseases. Echocardiography guidelines recommend that RV quantification be performed in the RV-focused view, which is theoretically more reproducible than the four-chamber (4Ch) view. However, differences between views in RV size and function measurements have never been systematically studied. Accordingly, the aim of this study was to compare (1) RV size and function parameters obtained from the RV-focused and 4Ch views and (2) test-retest variability between these two views.\nResearchfor care", "pred_label": "__label__POS", "pred_score_pos": 0.9789060354232788}
{"content": "Water and Society\nHuman societies strongly rely on access to water resources, which are essential to support livelihoods and provide favorable conditions for sustainable development. While benefiting from water services and struggling with water-related disasters (floods and droughts), humans also alter the hydrological regime by building dams, canals, levees, etc... This work aims to improve our understanding of human-water interactions, and the dynamics emerging from the feedbacks between hydrological and social processes.\nThe purpose of this project is to explore water-related issues and their link to sustainable development. To this end, it aims to better understand the dynamic relationships between hydrology and societies. This also require exploring how societies change the hydrological regime while, at the same time, hydrological changes simultaneously shape societies, i.e. socio-hydrology.\nAt the department, the studies dealing with the interface between water and society are organized around three main research lines:\nGlobal hydrology Engineering hydrology Socio-hydrology\nThe project activities are partly funded by VR and FORMAS and linked to the new scientific decade Panta Rhei (2013–2022) of the International Association of Hydrological Sciences (IAHS). The work is also carried out in support of three strategic research goals of the department: natural hazards, climate and sustainable development.", "pred_label": "__label__POS", "pred_score_pos": 0.7222659587860107}
{"content": "Benign metastasizing leiomyoma (BML) is the term used to describe multiple benign pulmonary leiomyomatous lesions occurring in patients with a previous history of uterine leiomyoma. On the other hand, pulmonary fibroleiomyomatous hamartoma (FLH) is also multiple nodules and the discrimination of the nodules between BML and FLH is not determined. We report the case of 36-year-old woman who had a previous history of uterine leiomyoma. The woman was referred to our hospital for evaluation of asymptomatic bilateral nodules in chest roentgenogram examination. A chest X-ray showed multiple nodules in bilateral lung. Chest computed tomography (CT) scan showed round nodules well-defined margins in bilateral lung. Thoracoscopic partial resection of the lung was performed. Pathological examination revealed that the tumor composed of spindle-shaped smooth muscle cells and its characteristics were remarkably similar to those of the previously resected uterine leiomyoma. Therefore, these lung tumors could be considered to be lung metastases from a uterine leiomyoma (benign metastasizing leiomyoma).", "pred_label": "__label__POS", "pred_score_pos": 0.8276690244674683}
{"content": "As cars get more and more feature packed, another equipment that has found into several new models is a digital video recorder (DVR), also known as a dashcam.\nHaving video evidence from a DVR will save from unnecessary “he said, she said” disputes arising from an accident.\nMany cars these days offer a built-in front-facing DVR while some manufacturers like Toyota will even offer a rear-facing camera for an additional RM 350, which is a small price to pay for better peace-of-mind.\nIf your car isn’t equipped with a built-in DVR, fret not as aftermarket solutions are available. To keep things simple, these are some features worth looking out for while shopping for a new DVR.\nVideo resolution: The minimum video resolution is 1080P, but 2160Pand 4koffer sharper video footage, at the expense of larger file sizes. Framerate: 30 frames per second (fps) is the norm these days, but 60 fpsis ideal. Higher fps also means larger file sizes Memory card: We recommend shopping for memory cards that are designed specifically for DVR usage, which are often labeled as ‘ High Endurance’. Manufacturers such as Transcend, Kingston, Samsung, and SanDiskoffer such cards. Memory card capacity: Go with at least 32GB, 128GBif you can afford. Display size. Good to have a display to align and adjust the DVR, but not a must-have. Some DVRs make do without a display, relying instead on WiFi connection for users to view recordings. G-Sensor. When the G-Sensordetects a crash, the DVR will lock the video recording to prevent it from being deleted or overwritten.\nApart from these requirements, we also recommend users to check actual video footage from the DVR before purchasing, as a blur video footage is useless as an evidence. It is also worth watching DVR reviews on YouTube before making a decision.\nFurthermore, it’s a good idea to watch video footages in various scenarios, not just in daylight. A good DVR is able to capture sharp footage regardless of the lighting conditions.\nBrands to look out for include\nViofo, Xiaomi, 70Mai, Transcend, and Blackvue. These are reputable and established brands that offer great cameras that various price points.\nAs for installing the DVR, we are aware that wire-tapping kits are common, but know that these methods will void the car’s warranty as it tampers with the car’s original wiring, so do it at your own risk.\nIt’s best to use the 12V socket/ cigarette lighter/USB as the power source.\nSo there you have it, a reasonably comprehensive guide on how to purchase a DVR.", "pred_label": "__label__POS", "pred_score_pos": 0.7082492113113403}
{"content": "This body of art is an on-going exploration of the intersection between the body, home, and the landscape.\nPrevious iterations of this installation play space can be found at these links:\nExcerpt from PhD Exegesis concerning this exploration:\n“This research grew from critiquing the sense of tension between my body and the environment. I found this tension repeated in my inquiry through my frustration at the visual dominance of mathematical space in my home’s interior and the surrounding urban environment. Critiquing this frustration led me to identify how habitual perception of these seemingly stable, standardised environments, in coincidence with mundane routine, can dull phenomenological depth: we don’t so much open out to these spaces as contain our subjectivities within them. Deliberation on these observations broke with this habitual perception at various points, prompting me to sense these ordinary environments more deeply as a world that strikes my body on its sensory surfaces.\nGaston Bachelard notes that “a house is first and foremost a geometrical object, one which we are tempted to analyse rationally.”\n[1] However, Bachelard elaborates, the lived house is transposed to the human plane whenever it “is considered a place of cheer and intimacy.” [2] In this fullness, the primacy of the home’s rational geometry yields to the home’s dream world. In seeking to plot the interaction of this geometry and its dream, I gradually disrupted the sensible partition of my common sense. In fact, my aversion to the mathematical, the utilitarian, and the standardised fixed in place my perception of inert, dead, matter.” (p. 135 – 136)\n[1] Bachelard,\nThe Poetics, 48.\n[2] Bachelard,\nThe Poetics,48.", "pred_label": "__label__POS", "pred_score_pos": 0.9791467785835266}
{"content": "I feel as though I live in my own reality. I uniquely experience the world, and at times, it separates me from others.\nMy emotions are very intense, and I struggle with both experiencing and controlling them. Other than experiencing these emotions, my relationships are most affected by BPD and my feelings.\nAt times, my emotions build-up, and I’m unable to keep them inside. I become erratic and unstable. Most of the time, I can keep my feelings inside. However, it is not that I am burying these feelings; my emotions change moment to moment. The difference is every one of my feelings is extreme and will often be viewed as an overreaction. I cannot burst, break down, or express these unpredictable and sometimes irrational emotions.\nWhen I am with others, I may not say much or always seem ‘there’ because my mental reality is going a mile a minute. I am processing what the other person says, I interpret and internally react; I manage my emotions.\nOften I struggle to relate. The issues I deal with daily are not the best conversation starters, and most people in my life cannot connect to what I go through. I find myself jealous of their goals and abilities. I am so proud of those I love, but it reminds me of what I cannot do and how easily it comes for them.\nBeing around others drains me. While I enjoy being around those I love, I need a lot of alone time. I can spend more time with those I am closest to. They understand me better than most, so they are more comfortable for me to be around. Although they may not understand my life, they support me and love me for who I am. Even so, I keep myself at a distance, protecting my mental state.\nThere are vital signs for when I have been around others too much or need time alone. I become irritable; I emotionally react to others and am often controlled by these emotions. I attach to those I’m around. I usually expect too much of people but am unable to communicate my needs. I will take others’ actions personally, so it affects me when I am pulling people too close.\nRelationships are essential for a happy and healthy life, but it is also necessary to have healthy boundaries and understand one’s needs. I need people in my life to connect, feel loved and supported, grow within relationships, and share experiences. Relationships are complicated for me, but they also make life worth it.", "pred_label": "__label__POS", "pred_score_pos": 0.9148963093757629}
{"content": "Symbolic Math Toolbox™ operates on numbers by using either numeric or symbolic arithmetic. In numeric arithmetic, you represent numbers in floating-point format using either double precision or variable precision. In symbolic arithmetic, you represent numbers in their exact form. This topic compares double-precision, variable-precision, and symbolic arithmetic.\nNumeric computations in MATLAB\n® use double-precision arithmetic by default. For example, evaluate the expressions 10001/1001, π, and . The results are converted to double-precision values. x = 10001/1001 y = pi z = sqrt(2) x = 9.9910 y = 3.1416 z = 1.4142\nFor more information about double-precision arithmetic, see Floating-Point Numbers. This arithmetic is recommended when you do not have Symbolic Math Toolbox or are using functions that do not accept symbolic input. Otherwise, exact symbolic arithmetic and variable-precision arithmetic are recommended. To convert a symbolic value to double precision, use the\ndouble function.\nVariable-precision arithmetic using\nvpa is the recommended approach for numeric calculations in Symbolic Math Toolbox. You can specify the number of significant digits when performing calculations with variable-precision arithmetic.\nFor example, use\nvpa to evaluate the fraction 10001/1001. By default,\nvpa evaluates inputs to 32 significant digits. Approximate the fraction 10001/1001 to at least 32 significant digits.\nvpa(10001/1001) ans = 9.991008991008991008991008991009\nApproximate the fraction to at least 8 significant digits. Change the number of significant digits by using the\ndigits function.\ndigits(8); vpa(10001/1001) ans = 9.991009\nIn variable-precision arithmetic, you can increase the number of significant digits for greater precision. Alternatively, you can decrease the number of significant digits for faster computations and decreased memory usage.\nSymbolic Math Toolbox provides the\nsym and\nsyms functions to perform exact symbolic computations. In symbolic arithmetic, you can perform computations involving numbers and variables in their exact form, such as\nx/2,\n2^(1/2), or\npi. The following three examples show several calculations that are performed in symbolic arithmetic.\nUse\nsym to create symbolic numbers. Express the irrational numbers π and in symbolic form.\nx = sym(pi) y = sqrt(sym(2)) x = pi y = 2^(1/2)\nWhen you declare a number, MATLAB automatically converts the number to double precision. For example, declare the integer\n80435758145817515 as the input argument of\nsym. The number loses its accuracy since it is bigger than the largest consecutive integer\nflintmax in double precision, which is\n2^53.\nZ = 80435758145817515 Zinaccurate = sym(80435758145817515) Z = 8.0436e+16 Zinaccurate = 80435758145817520\nsym.\nZaccurate = sym('80435758145817515') Zaccurate = 80435758145817515\nYou can then perform calculations with large integers using symbolic arithmetic accurately. For example, evaluate the sum of the cubes of three large integers.\nZ1 = sym('80435758145817515') Z2 = sym('12602123297335631') Z3 = sym('-80538738812075974') Zsum = Z1^3 + Z2^3 + Z3^3 Z1 = 80435758145817515 Z2 = 12602123297335631 Z3 = -80538738812075974 Zsum = 42\nWith symbolic arithmetic, you can solve a mathematical equation. For example, solve the quadratic equation\nax 2 + bx + c = 0. Use\nsyms to declare the variable\nx and the coefficients a, b, and c in the quadratic equation. syms a b c x eqn = a*x^2 + b*x + c == 0;\nFind the solutions using\nsolve and return them as symbolic expressions.\nsols = solve(eqn,x) sols = -(b + (b^2 - 4*a*c)^(1/2))/(2*a) -(b - (b^2 - 4*a*c)^(1/2))/(2*a)\nUse\nsubs to substitute symbolic values for the coefficients. Set\na = 1, b = 2, and c = 3. Return the solutions of the quadratic equation as symbolic numbers. solsSym = subs(sols,[a b c],[1 2 3]) solsSym = - (8^(1/2)*1i)/2 - 1 (8^(1/2)*1i)/2 - 1\nYou can then convert the symbolic solutions to floating-point format in double precision or variable precision.\ndigits(32); solsDouble = double(solsSym) solsVpa = vpa(solsSym) solsDouble = -1.0000 - 1.4142i -1.0000 + 1.4142i solsVpa = - 1.0 - 1.4142135623730950488016887242097i - 1.0 + 1.4142135623730950488016887242097i\nThe table below compares double-precision, variable-precision, and symbolic arithmetic.\nDouble Precision Variable Precision Symbolic Example 1: Evaluate sin(π) a = pi sin(pi) a = 3.1416 ans = 1.2246e-16 b = vpa(pi) sin(b) b = 3.1415926535897932384626433832795 ans = -3.2101083013100396069547145883568e-40 c = sym(pi) sin(c) c = pi ans = 0 Example 2: Evaluate 1 - 3*(4/3 - 1) a = 4/3 1 - 3*(a - 1) a = 1.3333 ans = 2.2204e-16 digits(16); b = vpa(4/3) 1 - 3*(b - 1) b = 1.333333333333333 ans = 3.308722450212111e-24 c = sym(4)/3 1 - 3*(c - 1) c = 4/3 ans = 0 Functions Used\ndouble\nvpa\ndigits\nsym\nData Type\ndouble\nsym\nsym\nRound-Off Errors Yes, the answer has 16 digits of precision. Yes, the number of digits depends on the precision used. No, the results are exact. Speed Faster Faster, depending on the precision used Slowest Memory Usage Least Variable, depending on the precision used Greatest", "pred_label": "__label__POS", "pred_score_pos": 0.9975943565368652}
{"content": "Is chasing storms ethical? After one profit-hungry chaser published the photograph of a dying child, it's time to re-evaluate if this is acceptable.\nAs someone who works as a disaster researcher and consults on emergency response, the fewer people we have in the path of destruction, the better. While yes, sometimes we still need ground-truth reports from spotters, but the NOAA satellite upgrades are getting pretty fantastic. Not only that, but spotters are trained, while anyone with a death-wish can go storm chasing. I'd even be open to debating if spotters are strictly necessary — just like I advocate for using robots to investigate active volcanoes, I'm all for getting \"good enough\" reports from machines instead of fantastically detailed reports from people in a risky situation.\nI already habitually watch chaser footage on mute; it may be time to flat-out stop watching to keep chaser footage as it escalates into disaster-porn.", "pred_label": "__label__POS", "pred_score_pos": 0.9854164123535156}
{"content": "Global Health Council was unable to submit statements on all (or some) official agenda items.\nGlobal Health Council, in collaboration with The Hunger Project, VillageReach, and Partners in Health notes that:\nCOVID-19 demonstrates that Universal Health Coverage in every community must be the top priority. Increased investment in all seven Global Action Plan accelerators must focus on community health systems so that tests and vaccinations can succeed.\nSustainable financingrequires a fair share of public budgets for delivery of health services and products at the tier of governance closest to the people. Community Health Centers(CHC) must be accessible (within 5km) and free to all, particularly in low-income rural communities. Every CHC must have access to clean water, sanitation,internet access, and well-trained healthcare workers. Community Health Workers(CHWs),particularly women, are critical to maintaining essential services and responding to the pandemic, ensuring every person is reached to halt misinformation, stigma, and to prevent gender-based violence. CHCs must institutionalize links with community associations, particularly women’s groups. Integrated centers to support determinants of health.CHCs can be the anchorfor one-stop access to all public services and education on health and nutrition. Health ministries should require Citizen Charters and mandatory social accountability mechanisms to ensure quality. Research & Development, innovation and access.Greater investment must be made to ensure CHWs have adequate personal protective equipment and fair compensation to support their role in deployment of testing and vaccines. Data and digital health. All CHWs should have access to remote continuing education and two-way communication at all times. Innovative programming in fragile and vulnerable states. The pandemic spotlights community resilience and the value of online platforms and connectivity to enable CHWs to network, access innovations, and share best practices even when higher tiers of government are disrupted.", "pred_label": "__label__POS", "pred_score_pos": 0.7056832909584045}
{"content": "A growing consensus across otherwise disparate perspectives on perception and action is that visually guided postural control emerges from within task constraints. Task constraints generate physiological fluctuations across various parts of the body. These fluctuations foster exploration of the available sensory information. For instance, standard deviation (SD) and temporal correlations of bodily sway can indicate how richly postural control samples available mechanical and visual information. Too much or too little SD entails destabilization of posture. Temporal correlations show a similar relationship, but they have also been shown to support carrying sampled information to other aspects of the postural system. The present study shows that increasing visual constraints on posture reveals an adaptive relationship between SD and temporal correlations of postural fluctuations. In short, changing the viewing distance of a fixation target shows that temporal correlations self-correct themselves across time and diminish SD across time as well. Notably, these relationships were strong for all viewing distances except the most comfortable viewing and reaching distance. This self-correcting relationship allows the visual layout itself to press the postural system into a poise for engaging with objects and events in the surrounding.\nbioRxiv Subject Collection: Neuroscience", "pred_label": "__label__POS", "pred_score_pos": 0.8633351922035217}
{"content": "The program's purpose is to provide the learner with knowledge and understanding of the fundamental management skills, behavior, and attitudes required to manage and lead laboratory teams towards achieving goals.\nHanine is a professional engineer with 16 years of experience managing numerous multidisciplinary projects. She has a keen focus on systems and procedures and manages projects driven by performance. She embraces change as an opportunity to succeed. With that mentality, she has often been put in the role of superuser or trainer for the implementation of new or improved systems.\nThis module introduces the changing laboratory environment, and presents the application of different management approaches in two laboratory scenarios.\nThis module provides a comprehensive understanding of the 6 basic management functions and its application in the laboratory environment.\nThis module will uncover key characteristics that will equip managers to handle situations and lead teams effectively.\nThis module summarizes the management fundamentals and key characteristics required to manage confidently and competently.", "pred_label": "__label__POS", "pred_score_pos": 0.8719061613082886}
{"content": "For many managers, it is impossible to stop working when the clock strikes five. Instead of wasting your evenings and weekends hunched in front of a laptop or worrying about unfinished tasks, employ one or more work/life balance tactics to ensure separation. In doing so, you'll be a more effective manager and a more present spouse, parent and friend.\nThe first step in creating a comfortable work/life balance is improving your time management systems. When you spend the day feeling rushed and slightly behind schedule, it is more challenging to leave the office with a sense of accomplishment and peace. To help, schedule 10-minute buffers on either side of each meeting or scheduled activity. These small chunks of time will give you time to think, reflect and transition to the next task without feeling overwhelmed.\nManagers are often overloaded with employee requests, meetings and supervisory activities. As the person in charge, you may feel obligated to handle everything yourself — usually, at the sacrifice of work/life balance. Instead, become a master of prioritization and delegation. Go through your list of outstanding tasks and mark those that can only be handled by you. Delegate all other tasks to your assistant or other employees on your team. Then, arrange the remaining tasks in order of importance and deadline. In doing so, you won't need to spend time at home worrying about a crucial task that went unfinished.\nDuring the day, many professionals are easily distracted by phone calls, emails and visiting co-workers. Each interruption kills productivity and puts you farther behind, which leads to poor work/life balance. If you're finding it difficult to focus, Forbes magazine suggests using your phone alarm to mark the end of the task at hand. Pick the most important project on your list, set the alarm for one hour in the future and get to work. Alternatively, instead of checking your email every five minutes, set an alarm for every two hours to indicate a dedicated email break. Alarms can eliminate the worry about missing meetings or losing track of time, so you can stay focused and improve overall time management.\nFor many professionals, mental preoccupation is the major challenge of achieving a healthy work/life balance. On busy or stressful work days, it can be difficult to transition from work to home; as a result, you end up worrying about a client over dinner or struggling to solve a management problem as you're falling asleep. To change your mindset from professional to personal mode, it can be helpful to create a small ritual at the end of each day. Do a five-minute mediation on the train or sitting in your car — close your eyes, let go of all thoughts and focus on your breath. You can also distract your mind by watching a short television show, reading a chapter of a favorite book or stopping to have a cocktail with friends. If you're a fan of fitness, go straight from work to the gym; an intense workout is an excellent way to clear your head.\nIt takes time to accomplish a comfortable work/life balance, particularly if you've spent years in workaholic mode. However, when you make an effort to leave work at work, you'll be a better manager and a happier person.\n(Photo courtesy of David Castillo Dominici / freedigitalphotos.net)", "pred_label": "__label__POS", "pred_score_pos": 0.8378990888595581}
{"content": "To Participate: Tweet a photo of you and your daughter, granddaughter, niece, cousin, etc., with the hashtag #shesinnocent.\nIn response to a new study from the Georgetown Law Center on Poverty and Inequality turned its attention to society’s perception of black girls and reported that “black girls were more likely to be viewed as behaving and seeming older than their stated age,” they also find that this dynamic is in place for girls as young as 5 years old.", "pred_label": "__label__POS", "pred_score_pos": 0.9329232573509216}
{"content": "The hydrogenation and oxide formation behavior of Fe-Ni-based metallic glasses (MGs), where measurements by the conventional gas-solid reaction method are difficult, is analyzed by a two-step approach: chronoamperometry followed by cyclic voltammetry (CA + CV). We introduce a concept of effective volume by measuring the thickness of the region where the hydrogen and hydroxyl ion interactions with Fe-based MG take place, which is characterized by high-angle annular dark-field scanning transmission electron microscopy. A very constant film thickness influenced by the OH- and H+ is confirmed by TEM, where the chemical homogeneity is maintained within this region. The weight percent of hydrogen and the corresponding hydrogen-to-metal ratio are determined as 1.16% and 0.56, respectively. When compared to previous studies conducted by the electrochemical- permeation method, the H/M ratio is found to be an order of magnitude larger. Electrochemical impedance spectroscopy (EIS) and subsequent equivalent circuit modeling (ECM) of the tested ribbons resolve the surface-diffusion processes for hydride formation and oxidation kinetics. This contribution provides a different perspective for the design and study of low-cost and high-performance amorphous nanofilms for hydrogenenergy applications, particularly when the common gas-adsorption methods are problematic.", "pred_label": "__label__POS", "pred_score_pos": 0.9993513226509094}
{"content": "Establishing a culture of sound business ethics within an organization is challenging, to say the least. Companies that market products that are not considered to be “healthy” for consumers have additional challenges. Using the online library, research a company that markets “unhealthy” products. Examples might include tobacco or alcohol companies but these examples are not all-inclusive. Respond to the following questions.\n1. Briefly describe the company and its product and the ethical dilemma associated with the production and distribution of its products.\n2. Describe how the perception of the product differs within cultures both within the United States and globally.\n3. How has this company handled the ethical implications of its product with a focus on social responsibility, integrity and\nbusiness ethics?\n4. Explain how leadership within the organization can instill a culture of ethics within the marketing department as they\nstrive to advertise a product that is not healthy for the customer.\nYour response should be a minimum of two double-spaced pages not including the title and reference pages. You are required to use at least one peer-reviewed source. Referenced sources must have accompanying in text citations complying with APA guidelines.", "pred_label": "__label__POS", "pred_score_pos": 0.8086748719215393}
{"content": "Diabetes pathology derives from the combination of hyperglycemia and hypoinsulinemia or insulin resistance leading to diabetic complications including diabetic neuropathy, nephropathy and retinopathy. Diabetic retinopathy is characterized by numerous retinal defects affecting the vasculature and the neuro-retina, but the relative contributions of the loss of retinal insulin signaling and hyperglycemia have never been directly compared. In this study we tested the hypothesis that increased retinal insulin signaling and glycemic normalization would exert differential effects on retinal cell survival and retinal physiology during diabetes. We have demonstrated in this study that both subconjunctival insulin administration and systemic glycemic reduction using the sodium-glucose linked transporter inhibitor phloridzin affected the regulation of retinal cell survival in diabetic rats. Both treatments partially restored the retinal insulin signaling without increasing plasma insulin levels. Retinal transcriptomic and histological analysis also clearly demonstrated that local administration of insulin and systemic glycemia normalization use different pathways to counteract the effects of diabetes on the retina. While local insulin primarily affected inflammation-associated pathways, systemic glycemic control affected pathways involved in the regulation of cell signaling and metabolism. These results suggest that hyperglycemia induces resistance to growth factor action in the retina and clearly demonstrate that both restoration of glycemic control and retinal insulin signaling can act through different pathways to both normalize diabetes-induced retinal abnormality and prevent vision loss.", "pred_label": "__label__POS", "pred_score_pos": 0.5064800381660461}
{"content": "In these desperate times due to the COVID-19, During Pandemic, Muslims should follow the teachings of Prophet Muhammad (PBUH). Considering the aspects of life, Prophet’s (PBUH) steps during such crises are also ideal for us.\nHe (PBUH) asked us to do following things during a pandemic; Advised locals to perform the Friday prayers within the home during the heavy rain. Requested people to self-isolate during a plague. He (PBUH) asked to maintain social distancing by not leaving the current area. Ensured that the authority took care of the people’s basic needs. Cooked soup to take care of the needy. We can also; Appeal people to donate generously and open state treasury for poor people. Find volunteers to help the people to get the necessary items. Counsel people to adopt hygiene rules in their routines. Prophet Muhammad (PBUH) never limited anyone to keep washing their hands five times every day when performing ablution. However, He (PBUH) recommended performing overall physical cleanliness. Purifying the way of living:\nAs the verse mentioned above states, our beloved Prophet Muhammad (PBUH) used to frequently encourage the Muslims to maintain measures of prevention in order to boost their immunity. In the past, few contagious diseases already took place.\nIn such cases, He (PBUH) always guided the believers of Allah to stay isolated. Also, if someone’s death took place because of the disease, He (PBUH) encouraged them to follow the rituals of burying on the spot.\nIt is also believed that at the time of emergencies, for instance, a war, He (PBUH) buried a lot of dead soldiers without giving them the regular washing and shrouding in order to complete the process quickly.\nRecalling the creator:\nYet, our Holy Qur’an states that;\nThe last messenger of Allah (PBUH), always emphasized and gave importance to: Upbring a responsible acquaintance who can become the origin of frequent betterment for everyone. Contribute to the current knowledge for benefiting humanity. Leaving behind charity to assist the poor and needy people.", "pred_label": "__label__POS", "pred_score_pos": 0.8687863945960999}
{"content": "Abstract\nChildhood spontaneous bladder rupture is an uncommon event, usually associated with bladder augmentation. Occasionally it occurs in normal bladders or non-augmented bladders with a predisposing factor. We present a unique case of misdiagnosed spontaneous bladder rupture in a non-augmented bladder exstrophy patient without evidence of lower urinary outlet obstruction. His acute abdomen mimicked appendicitis and was managed with laparoscopic exploration, intraperitoneal fluid drainage, appendectomy and bladder drainage. This case highlights the need for pediatric urological consultation by surgeons in the case of an acute abdomen with free fluid in a patient with an abnormal bladder.\nKeywords Acute abdomen Bladder exstrophy Bladder rupture Urinary ascites ASJC Scopus subject areas Pediatrics, Perinatology, and Child Health Urology", "pred_label": "__label__POS", "pred_score_pos": 0.6797630786895752}
{"content": "How does pregnancy impact iron levels?\nDuring pregnancy, the volume of blood in your body increases by about 30-50%. Iron needs are increased because the body uses iron to make extra blood to transport oxygen for the mother and baby during this time.\nDietary iron requirements can increase to as much as 30mg per day of iron during pregnancy, especially in the second and third trimesters. This may mean supporting a healthy diet with iron supplements when daily iron needs cannot be met through diet alone.\nHowever, food supplements are not a substitute for a varied diet and a healthy lifestyle. Also, you should not exceed the recommended daily supplement dose of iron without consulting your doctor or pharmacist.", "pred_label": "__label__POS", "pred_score_pos": 0.7022264003753662}
{"content": "According to the Department of Health and Human Services’ (HHS) 2012 Annual Rate Review Report, an ACA provision requiring insurance companies to justify rate increases above a certain threshold has slowed the rate of premium growth, resulting in $1 billion in consumer savings. A separate ACA medical loss ratio provision that limits insurance company spending on administrative costs has resulted in $1.1 billion in rebates to consumers, HHS announced.", "pred_label": "__label__POS", "pred_score_pos": 0.724543571472168}
{"content": "Abstract\nUrea Transporters are a family of membrane channel proteins that facilitate the passive transport of urea across the plasma membrane. UTs are divided into two subgroups, UT-A and UT-B. UT-As are primarily located in renal tubule epithelia and UT-Bs are highly expressed in renal descending vasa recta and extrarenal multiple tissues. Various urea transporter knockout mice exhibit low urine concentrating ability, which suggests that UTs are novel diuretic targets. With highthroughput screening of small molecule drug-like compound libraries, various potent UT inhibitors with IC50 at nanomolar level were identified. Furthermore, selective UT inhibitors exhibit diuretic activity without disturbing electrolyte and metabolism balance, which confirms the potential of UTs as diuretic targets and UT inhibitors as novel diuretics that do not cause electrolyte imbalance. This review article summarizes the identification and validation of urea transporter as a potential diuretic target and the discovery of small molecule UT inhibitors as a novel type of diuretics. UTs are a potential diuretic target. UT inhibitors play significant diuresis and can be developed to diuretics without disturbing electrolyte balance. Copyright© Bentham Science Publishers; For any queries, please email at [email protected]", "pred_label": "__label__POS", "pred_score_pos": 0.9478650689125061}
{"content": "Consumer Label Compliance Consumer labels are meant to be seen by potential customers in retail and online purchase settings.\nRegulation for consumer labels typically apply to chemical products that can be purchased at retail locations for personal or household use such as household cleaners, air fresherers, detergents, paints, lubricants etc. Regulations for these products not only differ by product and location, these regulations often differ from industrial regulations, and require a separate review(s).\nFor products in the United States of America we offer a\nCPSC (consumer product safety commission) label review service. For products in Canada we offer a CCCR (Consumer Chemicals and Containers Regulations) label service. For products in other locations, contact us for more details.\nNexreg’s Experts recommend reviewing each consumer label individually to ensure compliance for import and export. Contact us today!", "pred_label": "__label__POS", "pred_score_pos": 0.6784799098968506}
{"content": "2018 CSDMS meeting-012\n\"4) EarthLab\" is not in the list (1) Downscaling climate models for regional applications, 2) Dakota, 3) ANUGA, 4) Artificial Intelligence & Machine Learning, 5) Will not attend a clinic) of allowed values for the \"CSDMS meeting select clinics3 2018\" property.\nBrowse abstracts\nTowards a Quantitative Understanding of Parameters Driving Submarine Slope Failure: A Data Mining and Machine Learning Approach Jeffrey Obelcz, Naval Research Lab Stennis Space Center Mississippi, United States. jbobelcz@gmail.com Naval Research Lab Stennis Space Center Mississippi, United States. warren.wood@nrlssc.navy.mil\nSubmarine slope failure is a ubiquitous process and dominant pathway for sediment and organic carbon flux from continental margins to the deep sea. Slope failure occurs over a wide range of temporal and spatial scales, from small (10e4-10e5 m3/event), sub-annual failures on heavily sedimented river deltas to margin-altering and tsunamigenic (10-100 km3/event) open slope failures occurring on glacial-interglacial timescales. Despite their importance to basic (closing the global source-to-sink sediment budget) and applied (submarine geohazards) research, submarine slope failure frequency and magnitude on most continental margins remains poorly constrained. This is primarily due to difficulty in 1) directly observing events, and 2) reconstructing age and size, particularly in the geologic record. The state of knowledge regarding submarine slope failure preconditioning and triggering factors is more qualitative than quantitative; a vague hierarchy of factor importance has been established in most settings but slope failures cannot yet be forecasted or hindcasted from a priori knowledge of these factors.\nA new approach to address the knowledge gaps outlined above is using machine learning to quantitatively identify triggering and preconditioning factors that are most strongly correlated with submarine slope failure occurrence. This occurs in three general steps: 1) compile potential predictors of slope failure occurrence gridded and interpolated at desired resolution, 2) compile predictands (specific values that we wish to predict), and 3) recursively test predictor/predictand correlation with observed data until the strongest correlations are found. Potential predictors can be parsed into categories such as morphology (gradient, curvature, roughness), geology (clay fraction, grain size, sedimentation rate, fault proximity), and triggers (seismicity, significant wave height, river discharge). Predictands (i.e. training data) are various proxies for slope failure occurrence, including depth change between bathymetric surveys and sediment shear strength. The initial test sites are heavily sedimented, societally important river deltas, as they host both frequent slope failures and ample predictor/predictand measurements. Once predictors that strongly correlate with submarine slope failure occurrence are identified, this approach can be applied in more data-poor settings to further our current understanding of global submarine slope failure distribution, frequency, and magnitude.", "pred_label": "__label__POS", "pred_score_pos": 0.7362313866615295}
{"content": "Information technology services are needed by all companies. A wide range of IT hardware and software solutions are used by businesses and organizations. External support services may be needed to manage these setups. The services are needed if there is no internal IT team to handle such jobs or such a team is not capable of handling the tasks at hand. The company offering IT management services offers a wide range of services. The types of services such a company offers depend on its specialty. For example, a company may offer only IT hardware repair services while another one may offer only software related services.\nThese companies can offer support services for IT asset management, performance management, security, troubleshooting, diagnostics, system repair, administration and remote monitoring, among others. They can help install all types of IT hardware and software setups. They have specialists to install network, data backup and cloud systems. Their services can be hired on per job, annual or regular basis.", "pred_label": "__label__POS", "pred_score_pos": 0.5411276817321777}
{"content": "Principal contributor: Hannah Breul Source:Colonial Pipeline\nFollowing an outage that began on October 31, Colonial Pipeline’s Line 1 resumed shipping gasoline early Sunday morning. Line 1 carries gasoline from the Gulf Coast to as far east and north as North Carolina, and is a key supply source for several states in between and beyond. When operating at full capacity, Line 1 carries 1.4 million barrels per day of gasoline from the U.S. Gulf Coast to a major junction and product storage hub in Greensboro, North Carolina. Various branches provide gasoline to central and eastern Tennessee, southern Georgia and eastern and western portions of Virginia. Beyond Greensboro, other portions of Colonial’s system send gasoline, diesel and other transportation fuels to Maryland and New Jersey.\nAccording to Colonial Pipeline, gasoline is expected to reach as far north as Charlotte, North Carolina, within a day of Line 1’s restart. Gasoline shipments on Colonial’s system are expected to reach as far north as Baltimore, Maryland, by Tuesday and to reach their northern terminus in Linden, New Jersey, near New York Harbor, by Wednesday.\nTotal motor gasoline stocks in the Lower Atlantic states (defined by Petroleum Administration for Defense District, or PADD, 1C) were at relatively high levels before the October 31 outage, with 27.5 million barrels, or nearly 20% above the previous five-year average, in storage as of October 28. Inventory data for the week ending November 4 will be available on Wednesday, November 9 in the Energy Information Administration’s (EIA’s)\nWeekly Petroleum Status Report.\nDespite the recent outage, GasBuddy, a crowd-sourced retail gasoline price comparison site, showed retail prices in most areas in the Southeast below $2.35 per gallon (g) as of November 7. EIA’s weekly retail price for regular gasoline for the Lower Atlantic (PADD 1C) was $2.17/g as of Monday, November 7, virtually unchanged from the previous week, and 6 cents/g below the national average.\nA previous disruption to Line 1 flows from September 9 – September 21 resulted in record changes in motor gasoline stocks in both the Lower Atlantic states and the Gulf Coast states during the week ending September 16. During that week, total motor gasoline stocks in PADD 1C fell by nearly 6 million barrels, from 28 million barrels to 22 million barrels. Meanwhile, Gulf Coast (PADD 3) gasoline stocks increased by nearly 4.8 million barrels. In the week ending September 23, stocks grew modestly in both regions, indicating that resupply had begun to reach the Lower Atlantic region.", "pred_label": "__label__POS", "pred_score_pos": 0.964722216129303}
{"content": "Linear Investments provides a summative overview on the performance of Hedge Funds in October and the first three quarters of 2019.\nHedge Funds posted the best performance this year since 2013.\nAccording to Bloomberg hedge funds are gaining momentum, surpassing uncertainties in markets and geo-politics having gained 4.9% on average in the first three quarters of 2019. Eurekahedge Hedge Fund index similarly returned 5.7% over the same timeline with nearly 30% of the managers within the index having recorded double digit returns.\nAs at the end of September, Eurekahedge reported that assets under management within the hedge fund industry stood at US$2.27trillion, illustrating a performance growth of US$98.3 billion year-to-date. Leading performance for the year within the Eurekahedge Index were Global Macro and Equity Long/Short strategies, while geographically Latin America focused funds led returns. Bloomberg similarly highlighted equity strategies as leading in terms of gains, followed by event-driven strategies.\nThe growth has come despite a year of uncertainties roiling markets; Brexit, US-China trade war, impeachment inquiries to name but a few. Nevertheless, in the continuation of the longest bull-run in US history, hedge funds have continued to trail the S&P 500 which rallied 18.74% in the first three quarters of 2019. Whilst Eurkeahedge reports US$120.8bn in investor redemptions from hedge funds over the year, it also shows redemptions slowing with net outflows in Q3 reported as US$34.3bn versus Q1 US$46.4bn. Now in the final quarter of 2019, the challenging geo-political backdrop remains in addition to relatively unchartered monetary policy regimes and a slowing global economy.\nAranca Research Group cites that the top challenges in the hedge fund community include growing AUM, fee pressures and keeping up with regulatory change.\nHowever, funds that are already performing well are expected to continue to capture institutional investment. This growth will be further driven by HNWIs in emerging markets. As we look to the year ahead, it will be up to investors to navigate these nuances to ensure the best returns.\nLinear has always held the stance that as volatility returns to the market the Alternative area will start to strengthen in risk return patterns and become more attractive than when the market is totally directional.", "pred_label": "__label__POS", "pred_score_pos": 0.5531421899795532}
{"content": "The process of ending a marriage can be daunting. Even after deciding to divorce, either spouse may be overwhelmed by the thought of court hearings, custody disputes and asset division.\nWhen a couple files for divorce in Florida, they can pursue a simplified marriage dissolution if they meet certain criteria.\nSimplified divorce\nWith this process, the state does not require financial disclosure. However, either party can ask for disclosure during negotiation of a simplified divorce agreement. A married couple can request a simplified marriage dissolution in Florida if:\nAt least one spouse has lived in Florida for at least six months Both spouses agree to waive spousal support. They reach an agreement on property and debt division. They have no children younger than 18 together and the wife is not currently pregnant. Standard divorce\nCouples who do not meet the above requirements must file for a standard divorce in Florida. This process requires full financial disclosure within 45 days of filing. The spouse who initiates the divorce must submit a petition that details his or her preferences for child custody, property division and spousal support as applicable. He or she must serve the other spouse with the petition along with the hearing date scheduled by the court. The responding spouse can submit his or her own petition within 20 days of receiving legal notice.\nFlorida may require couples who cannot agree on the key issues in divorce to go to mediation. If mediation does not prove successful in helping the couple reach a fair agreement, the judge will make a decision about contentious issues on the couple’s behalf.", "pred_label": "__label__POS", "pred_score_pos": 0.92484050989151}
{"content": "DNB expects that banks understand the potential impact of climate-related risks on their balance sheets. Any material climate-related risk should be governed in a way consistent with sound risk management similar to any other type of material risk. DNB’s interpretation of how existing regulation applies to climate-related risk management is detailed in the Q&A.\nDNB has assessed existing practices in the Dutch banking sector related to the management of climate-related risks. This Good Practice document aims to share some of the good practices that were observed by DNB, with the intention to inform the sector as a whole. These good practices provide non-binding guidance on how banks can organise their processes and procedures to manage the climate-related risks related to their activities.\nClimate change poses new challenges to the risk management of banks. Both physical and transition risks can be characterised by significant uncertainty and nonlinearity, while their probability of occurrence may not be reflected in historical data. These challenges thus warrant timely and concerted actions by banks, but also by the wider private and public sector.", "pred_label": "__label__POS", "pred_score_pos": 0.9986281991004944}
{"content": "Know where your food comes from. Our 2019 weekly share list.\nHelping The Community\nOrganic Local CSA produce contains fewer pesticides and chemicals such as fungicides, herbicides, and insecticides are widely used in conventional agriculture, and residues remain on (and in) the food we eat. Organic food is often fresher because it doesn't contain preservatives.\nCSA's are good for your health, community, and environment.", "pred_label": "__label__POS", "pred_score_pos": 0.553351640701294}
{"content": "@MISC{Dhenesh_observationsof, author = {Virallikattur S Dhenesh and Elena Sitnikova and Jill Slay}, title = {observations of team meetings in organisations}, year = {} }\nShare\nOpenURL\nAbstract\nTeams collaborate in different contexts within organisations to share information with its members in achieving their targets. Collaborations with face-to-face meetings are prevalent despite the emergence of numerous tools to support distributed team collaborations. However, the nature of tool-support for team collaborations in the last decade was focused on supporting distributed and web-mediated meetings. Furthermore the tools were either not designed to support all the processes within team collaboration or not readily adopted by users. Literature on developing an integrated tool-support that includes all the potential processes within a meeting, and learning lessons whilst designing tools to improve the state of their adoption is largely unexplored. This paper reports on a qualitative study that observed twenty team meetings from five organisations in South Australia and analysed the data using a grounded theory approach to generate stories on team activities. The stories were used to develop a tool-kit framework and lessons on providing a tool support for team meetings. The proposed framework consists of a list of potential hardware and software tools that could be introduced within a team meeting to support the team activities.Lessons were learned on the potential processes that would require tool support, participants ’ requirements and how technology", "pred_label": "__label__POS", "pred_score_pos": 0.6474605202674866}
{"content": "Thursday, March 9, 2017, 6:00 PM | Leave Comment\nBankruptcy affords those in significant financial distress a clean start. However, the fact of bankruptcy remains on your credit history for up to a decade.\nIf you seek to avoid the harm to your credit and ability to buy a home or other major ticket items, consider these tips to suppress your debt burden.\nNo Substitute for Cash\nRelying on\ncredit for staplesand regular living expenses can unnecessarily increase your debt load.\nCredit card debt should not pay for disposable items such as groceries or most restaurant trips.\nWhen you turn to credit for these purchases, you face interest charges for items things with little or no repetitive use and that no longer exist.\nUse cash or your checking account for electric, gas, water, garbage, cable and other regular monthly bills.\nGetting Financially Lean\nIf you find money tight, consider eliminating certain services.\nFor instance, consider removing data plans from your smartphone and tablets and using Wi-Fi at your home or at establishments that offer it free of charge.\nReduce monthly payments by downgrading or eliminating satellite or cable television or satellite packages, especially those with channels you don’t watch.\nAbove and Beyond\nPay more than the minimum payment. Consumer Reports states that it would take you\n24 yearsto wipe out a $2,000 balance on an 18-percent credit card if you paid only two percent per month.\nExtra payments on small balance credit cards can reduce your interest outlays on especially high-interest cards.\nAlternatively, devote extra amounts to the lower-balance accounts and reserve minimum payments for the high-balance cards.\nUsing tax refunds can make a significant dent in your debt. As you pay off cards, you’re credit score may increase because zero-balance accounts equate to more available credit.\nHome Equity Loan\nWith a home equity loan, you borrow against your home’s value, less what you already owe on it.\nUsing the home equity loan proceeds, you pay off existing credit cards, medical bills and other unsecured debt.\nFurther, the lower interest rate on a home equity loan replaces the higher interest rates on your credit cards.\nHowever, a home equity loan effectively converts unsecured credit to a secured loan. If you miss payments, you could lose your home to foreclosure.\nCredit Counseling\nFind a reputable credit counseling agency that can help examine your credit condition, negotiate for lower rates and consolidate your credit cards, student loans, medical bills and other unsecured debt.\nIn a debt management plan arranged through a credit counselor, you deposit an amount monthly with the agency. With your deposit, the agency pays these creditors according to a set plan. Depending on the plan or creditor, you may avoid late fees or interest.\nConsult your state’s Attorney General’s office, a consumer protection organization or an agency on the United States Trustee Program’s approved pre-bankruptcy counseling list.\nIf bankruptcy is your last resort against mounting debt, contact an attorney like\nLazaro Carvajal who can guide you through the procedures and requirements for getting your debt discharged. Throw us a like at Facebook.com/doable.finance", "pred_label": "__label__POS", "pred_score_pos": 0.934277355670929}
{"content": "Companies based in the Philippines, the government, and the academe recently met to discuss the implications of the future of work. The\nFuture of Work Symposium, organized by Austrade Manila on behalf of Macquarie University in Makati city, provided a platform for all involved to discuss issues challenging businesses undergoing digital transformation. Issues included meeting supply of needed skills in the new workforce; concerns related to staff hiring, on-boarding and training; massive job losses due to automation; and the increasing need for lifelong learning.\nParticipants of the event included high-level representatives from the Philippine government, private and academic sectors, Australian businesses, business process outsourcing firms, and multinational companies located at the Clark Freeport and Economic Zone.", "pred_label": "__label__POS", "pred_score_pos": 0.999683678150177}
{"content": "It is often thought that young children are incapable of understanding transgender and nonbinary identities, but this is untrue. Additionally, \"No harm is done on an individual or societal level if a child has the option of exploring their gender identity from early on,\" even if the child later turns out to be cisgender.[1]", "pred_label": "__label__POS", "pred_score_pos": 0.9998011589050293}
{"content": "X-linked Charcot-Marie-Tooth (CMTX) disease is a common inherited degenerative disorder of the peripheral nerve. Previously, our laboratory identified a large New Zealand/United Kingdom (NZ/UK) family mapping to the CMTX3 locus (Xq26.3-27.1). We have now identified a second large, Australian X-linked CMT family that links to the CMTX3 locus. This new family has the same phenotype as our previously described CMTX3 family, with slightly milder disease in males than CMTX1 and asymptomatic carrier females. This study also includes the re-analysis of one of the original US pedigrees reporting the CMTX3 locus. The large Australian family shared the complete disease haplotype with our original NZ/UK family, while the American family shared only the distal portion of the disease haplotype. Comparison of the frequency of the CMTX3 haplotype to the normal population showed strong statistical evidence (p < 0.0001) indicating that the smaller shared haplotype is identical by descent. This suggests that the new CMTX3 family, our previously reported family, and the original American CMTX3 family have a common ancestor, and the disease in these families is caused by a founder mutation. The ancestral recombination observed in the American family refines the CMTX3 interval to a 2.5 Mb region between DXS984 and DXS8106. In this region, 11 out of the 15 annotated genes have been excluded for pathogenic mutations.", "pred_label": "__label__POS", "pred_score_pos": 0.5772755146026611}
{"content": "Purpose: The aim of this meta-analysis and systematic review was to determine whether bleeding prophylaxis benefits patients after colonoscopic polypectomy. Methods: A systematic review of the literature was performed to find prospective randomized controlled trials of postpolypectomy hemorrhage prophylaxis. Studies were selected according to specific criteria and analyzed to generate pooled data. Results: Eight studies encompassing 2,595 polyps met the criteria for the meta-analysis. The rate of early bleeding was significantly decreased relative to the control when a single prophylactic technique was used [2.58% vs. 8.15%, OR = 0.34 (95% CI, 0.20-0.58), P < 0.0001]. The use of multiple prophylactic techniques resulted in a lower early postpolypectomy hemorrhage rate compared with the use of a single prophylactic technique [0% vs. 8.41%, OR = 0.12 (95% CI, 0.03-0.47), P = 0.002]. The late bleeding rate did not differ significantly between the monotherapy and control groups [0.61% vs. 1.39%, OR = 0.37 (95% CI, 0.11-1.28), P = 0.12], and the use of combined preventative techniques did not significantly decrease the late postpolypectomy bleeding (PPB) rate compared with use of a single prophylactic method [1.43% vs. 2.05%, OR = 0.70 (95% CI, 0.32-1.55), P = 0.38]. Conclusion: Prophylactic endoscopic treatments are effective at reducing early PPB after colonoscopic polypectomy. However, patients with late PPB may not benefit from bleeding prophylaxis.", "pred_label": "__label__POS", "pred_score_pos": 0.5721820592880249}
{"content": "With more stringent health and safety legislation, utilities need to identify, assess, and control workplace risks. Lone worker safety has become a focus across utility organisations, with many staff travelling long distances, driving vehicles after hours, and undertaking maintenance and development of utility infrastructure in hazardous environments.\nAcross Australia and New Zealand, the shift to privatised utility networks, expanding infrastructure, growing populations and tightening margins are driving the need to optimise operational efficiencies and effectiveness, while managing risk. Ensuring better, more affordable customer outcomes requires maximising the productive utilisation of existing organisational fleet and assets. Sharing resources and improving transparency are two ways to achieve this.", "pred_label": "__label__POS", "pred_score_pos": 0.5818912982940674}
{"content": "Abstract\nA study was conducted to understand the three steps of the NF-κB pathway, IκB degradation, processing of NF-κB precursors, and activation of IKK and other kinases. The study also highlighted how deubiquitination enzymes negatively regulate the NF-κB pathway and how dysfunction of these enzymes lead to human diseases. It was observed that NF-κB pathway provided an understanding of roles of ubiquitin in cell signaling including signal-dependent degradation of an inhibitor that further lead to a rapid activation of a signaling cascade, limited proteolysis of a precursor protein by the proteasome, and activation of protein kinases. The ubiquitin system played a significant role in diverse signaling cascades leading to NF-κB activation. The study also concluded that pervasive role of ubiquitin in NF-κB pathways showed the regulatory potential of ubiquitination and deubiquitination.\nASJC Scopus subject areas Chemistry(all)", "pred_label": "__label__POS", "pred_score_pos": 0.9999785423278809}
{"content": "Description\nCystone naturally promotes a healthy urinary tract and helps maintain normal urine composition and mucosal integrity. It is a natural aid in maintaining healthy water management and relieves temporary water – weight gain.\nBALANCES PH OF URINE: It manages the production and composition of urine, thereby balancing its pH, which is often a cause for UTI’s and the burning sensation while emptying your bladder.\nHELPS REDUCE STONE FORMATION: Cystone works by managing the concentration of calcium salts in the blood, which contributes to the formation of stones, and aids in breaking them down and expelling them from the body. It does this by acting on mucin, the sticky substance which binds the particles together to form stones. NATURAL DIURETIC: Cystone naturally increases the excretion of excess water from the body, thereby increasing urine production and reducing bloating. This reduces the chances of you catching repeat urinary infections. ALL NATURAL SUPPLEMENT: As it is made of natural ingredients based on Ayurveda, Cystone does not exhibit any side effects as long as the recommended dose and use is not exceeded.", "pred_label": "__label__POS", "pred_score_pos": 0.7945690155029297}
{"content": "Norwegian Cruise Line, based in Miami, is one of the most innovative companies operating in the cruise industry. As part of their commitment to the environment, Norwegian Cruise Line applied biocide free, Intersleek foul release coatings to the 78,309 GRT Norwegian Sun when it was built in Germany in 2001.\nTen years later, the Intersleek\n® system has only needed touch-up repairs, significantly reducing overall paint volume, packaging, waste and VOC emissions. Because full coats were not necessary, dry-docking time and costs were also significantly reduced.\nDuring Norwegian Sun’s dry dock in the Bahamas in January 2011, it was noted that the Intersleek® system had performed well and was in good condition with no animal or weed fouling. Commenting on the performance of the Intersleek\n® system, Mr. Brian Swensen, Senior Vice President, Technical Operations, Norwegian Cruise Line said, “We are very pleased with the performance of the Intersleek ® system. At Norwegian Sun’s two interim dry-docks, we only applied a total of 600 litres of Intersleek®. For a standard antifouling system, we would have used approximately 6,000 litres. This has resulted in a 90% reduction in VOC emissions and a 100% reduction in biocide release. The fact that no full coats were required meant that the dockings in 2004 and 2007 were completed ahead of schedule with lower paint and application costs than expected.”\nIntersleek\n® has now been applied on more than 500 passenger vessels over the last 15 years, including 100 cruise vessels. Many of these vessels have achieved significant efficiency improvements with reduced environmental impact.", "pred_label": "__label__POS", "pred_score_pos": 0.7679742574691772}
{"content": "Coat tight-fitting metal parts, such as gears, clutches, and press-fit assemblies, with these lubricants before sliding them together to make assembly easier. Once assembled, they provide initial lubrication in equipment before oil has a chance to flow.\nMineral-oil-based lubricants, derived from petroleum, are more economical than synthetic-oil-based lubricants. Lubricants with zinc prevent corrosion.\nLubriplate No. 105 is often used to assemble motor and engine components. It has excellent moisture resistance.", "pred_label": "__label__POS", "pred_score_pos": 0.997100830078125}
{"content": "Summary\nThe Grazing Land Management (GLM) education package aimed to contribute to increased awareness, understanding and uptake of grazing management strategies and practices that are both profitable and sustain the natural resource base of the grazing enterprises. The initial development of the package highlighted the need for regionally specific information on which graziers based their decisions. Accordingly, this project supported the customisation of the GLM package in the Southern Gulf, Desert Uplands and Channel Country regions.\nCustomisation of the regionally specific GLM packages involved the following steps: 1. Collation of locally relevant publications, information, photos and data sets. 2. Development of a land type framework derived from producer surveys, reference material and discussions with agency staff. 3. Develop a local case study property which is used to demonstrate the financial and natural resource management implications of changed grazing management practices on land condition. 4. Review of materials at a technical review and pilot workshop which includes local producers who provided critical feedback to the regional developers. 5. Publication which includes formatting by desktop publishers and editing to ensure consistency of style and appropriate language in accordance with the MLA EDGEnetwork style guide. All materials were tested in a technical review pilot within the region, with the outcomes used to adjust the materials prior to finalisation. All materials were finalised, formatted by desktop publishers and edited for style and consistency in accordance with the publishing standards of MLA EDGEnetwork. As the workshop is delivered in these regions, locally relevant case studies, photo standards and pasture growth measurements will be accumulated and integrated into the workshop materials.", "pred_label": "__label__POS", "pred_score_pos": 0.5146551132202148}
{"content": "Disruptive mood dysregulation disorder (DMDD), a newcomer to psychiatric nosology, addresses the need for improved classification and treatment of children exhibiting chronic nonepisodic irritability and severe temper outbursts. In recent years, many of these children have been diagnosed with bipolar disorder, despite the lack of distinct mood episodes. This diagnostic practice has raised concerns, in part because of the escalating prescription of atypical antipsychotics. This article provides an overview of the limited literature on DMDD, including its history and relevant studies of assessment and treatment. A case study is included to illustrate key points, including diagnostic issues that clinicians may encounter when considering a diagnosis of DMDD.\nREAD FULL ARTICLE From ajp.psychiatryonline.org", "pred_label": "__label__POS", "pred_score_pos": 0.9773234128952026}
{"content": "Clinical Oncology deals with the nonsurgical aspects of cancer, including therapeutic administration of ionising radiation (radiotherapy) and chemotherapy. Clinical oncologists determine which treatment to use by considering a range of factors including tumour type, the site of the tumour, the stage of the disease and the patient’s general health. *2019 Journal Impact Factor was established by dividing the number of articles published in 2017 and 2018 with the number of times they are cited in 2019 based on Google Scholar Citation Index database. If 'X' is the total number of articles published in 2017 and 2018, and 'Y' is the number of times these articles were cited in indexed journals during 2019 then, impact factor = Y/X", "pred_label": "__label__POS", "pred_score_pos": 0.6972928643226624}
{"content": "Middle School Basketball Rules\nFor boys and girls in middle school, basketball promotes teamwork and sportsmanship in addition to athletic competition. Although rules vary slightly by league, middle school players all follow the basics of the game. The general rules governing middle school basketball create a fast-moving game for spectators and an energetic sport for participants.\nBasic Basketball Rules\nIn basketball, players on teams of five compete to achieve the most points at the end of the designated time. Teams score points by throwing the basketball into the team's respective metal hoop, located at each end of the court. To achieve this, players move the ball to their team's end of the court by dribbling or passing the ball to other players. The ball can be passed with one or both hands, but once both hands touch the ball, the same player cannot dribble it again. Players cannot walk with the ball and cannot kick it.\nPlayers score two points for baskets made inside the designated three-point line, and three points for shots made when the player is standing outside that line. Free throws score one point. A player takes a free throw shot when she has the ball as an offensive player and then is the victim of a foul, such as an elbowing from a defensive player.\nTo properly play defense when players from the other team possess the ball, a player stays near a corresponding offensive player, but does not impede her movement or physically push or harm her in any way. When a player takes a shot, players may not block the ball if it has already started to descend into the goal.\nIf the ball rolls out of boundary lines marked around the perimeter of the court after a player has touched it or had possession of it, or if a player steps out of bounds, the opposing team chooses a player to throw the ball in to another player on that team, and gains possession of the ball.\nMiddle School Rule Differences\nIn middle school basketball, students usually play a shortened game. For instance, in the National Basketball Association, players challenge each other over the course of four 12-minute quarters, with a 15-minute halftime. Middle school players, in contrast, play quarters that last seven or eight minutes long.\nEach basketball league or association governs its own league's play. In some districts, middle school players follow high school rules and others follow rules for youth play. In youth play, according to the International Basketball Federation, goals are lowered for youth teams, the courts are smaller and the balls themselves are smaller than professional regulation balls.\nIn general, the rules of middle school basketball work to make the game less frustrating to the players. For instance, some middle school leagues ban zone defense. Zone defense is a technique of having multiple defensive players guarding multiple offensive players at the same time. In middle school basketball where zone defense is banned, each player guards only one other player, which is called man-to-man defense.\nReferences\nWriter Bio\nAndrea Lott Haney writes articles and training materials for food industry publications. Having studied foodservice sanitation, nutrition and menu planning at Purdue University, Lott Haney has more than 10 years of experience as a catering and event planner for luxury hotels and currently tours the Midwest as a corporate customer service trainer and consultant.", "pred_label": "__label__POS", "pred_score_pos": 0.5441656112670898}
{"content": "The Compliance Life details the journey to and in the role of a Chief Compliance Officer. How does one come to sit in the CCO chair? What are some of the skills a CCO needs to success navigate the compliance waters in any company? What are some of the top challenges CCOs have faced and how did they meet them? These questions and many others will be explored in this new podcast series. Over four episodes each month on The Compliance Life, I visit with one current or former CCO to explore their journey to the CCO chair. This month, my guest is Katie Smith who is the Vice President for Ethics at Assurance. She previously served as Assistant Vice President and Chief Ethics Officer for USAA and Executive Vice President and Chief Compliance and Ethics Officer at Convercent.\nKatie is passionate about compliance, having worked in the field for 20 years, building high-performing teams and increasing employee engagement by up to 300%. She has proven expertise in building and promoting talent, creating a trust-based culture, anti-corruption, code of conduct, conflict of interest, marketing internal programs, training and awareness, investigation excellence, data privacy and process efficiency. She is a much sought after public speaker and contributor featured in Wall Street Journal, Time, Fortune, NBC and Compliance Week. Katie’s commitment to the compliance profession is well as she currently sits on the Board of Directors of the Ethics and Compliance Initiative (ECI).\nIn this third episode, we take up a topic not often discussed by compliance professionals: when is it time to move on? Katie gives six pivots points, including the following: (1) Incredible opportunity – lateral, upward, or balance; (2) Jaded. Objectivity is dying a slow death; (3) Bored as you have stood up a program, survived a crisis, now what do you do? (4) Retire and stay on Autopilot; (5) The support for you program is simply not there; and (6) Died on a compliance hill. Katie provides guidance on what compliance professionals should do if they find themselves in any of these situations.", "pred_label": "__label__POS", "pred_score_pos": 0.8231099843978882}
{"content": "A team of researchers from McMaster University in Canada made a big discovery with the help of a 16\nth century mummy. This belonged to a two-year-old child who was initially believed to have been suffering from smallpox. However, they decided to perform a genetic analysis and discovered the actual cause of death was hepatitis B. This proves the disease has been around for more centuries than we thought. The mummy had actually died of hepatitis B\nThe child must have died sometime around 1569, and was found buried in Naples, Italy, in the Basilica of Saint Domenico Maggiore. Researchers discovered the mummy between 1983 and 1983, and saw it was covered in some strange marks which resembled smallpox. After studying the marks, they discovered traces of smallpox particles in them, so they assumed this was the cause of death.\nThese findings were important for establishing the evolution of smallpox throughout time. Researchers couldn’t tell how early the disease appeared, and this would have been the oldest evidence of its presence in the Medieval world. However, it turned out it wasn’t actually smallpox that killed the boy.\nHepatitis B left marks on the body similar to those of smallpox\nThis wasn’t the only disease which could leave blister marks on a person. Hepatitis B is an infection of the liver but, if small children contract it, they are left with similar marks on the face, legs, arms, and bottom. On all these areas, the mummy showed blisters.\nTo solve the mystery, researchers collected samples from the skin and bones of the mummy and performed a genetic analysis on them. This way, they reconstructed the genome of the disease which killed the boy. The result wasn’t smallpox, but hepatitis B.\nThey also performed an advanced type of electron microscopy, and what they found didn’t resemble none of the viruses they were looking for. This way, they concluded that, during mummification, the virus might have been altered and took an unrecognizable form. Also, this explains why they mistook the virus for Variola at first (the virus that causes smallpox).", "pred_label": "__label__POS", "pred_score_pos": 0.6230840682983398}
{"content": "Reef structures and stabilisation to facilitate reef recovery\nBioballs\nTM or Subcon Mushrooms\nSmall (a few hectares, a single reef)\nNovel, human-made structures for coral settlement (new shapes, sizes and surfaces) can enhance reef structural complexity and provide surfaces to promote coral resettlement and growth. They can range from micro-scale engineering to artificial reefs.\nPlacing large, manufactured structures such as Bioballs\nTM or Subcon Mushrooms onto degraded reefs could facilitate coral resettlement, improve survival rates, enhance herbivory, fish diversity and growth of immobile organisms.\nThey would be deployed from large barges.", "pred_label": "__label__POS", "pred_score_pos": 0.9458761215209961}
{"content": "The Tier 2 Visa is granted to international skilled workers who have been offered a job in the UK. Once you get your sponsorship through your UK-based employer, you can apply for your permit. This status allows you to remain in the country until the date mentioned on your certificate, or for a maximum period of 5 years.\nHowever, it is not uncommon for workers to have their employment terminated early. Whether this is due to resignation, dismissal, or any other reason, it affects your immigration status. Consequently, your Tier 2 Visa will be curtailed. At this point, you must find a new sponsor or leave the UK within 60 days (or until the end of your visa, if this is shorter).\nDealing with a termination of employment and a Tier 2 Visa curtailment is inevitably a stressful experience. However, it is crucial to follow the Home Office’s guidelines and strategically plan how to proceed. Whether you wish to lawfully remain in the UK or to go back to your home country, there are different paths that you can follow.\nWhat are the responsibilities of a Tier 2 Sponsor?\nWhatever the reasons for your termination of employment, your sponsor must report this change of status to the Home Office within 10 days of your contract ending. The UKVI must also be informed of your last known address so that you and your employer can receive a copy of your Tier 2 Visa curtailment letter.\nIf you are submitting your notice of resignation, it is recommended to send a copy to the UKVI along with your planned leaving date.\nAfter the date reported in your curtailment letter, you have 60 days to either get a new sponsor, apply for a new visa, or leave the country.\nTermination of employment on a Tier 2 Visa: moving to a new job\nThe termination of your current employment in the UK does not necessarily mean that you must leave the country. You still have an adequate timeframe within which you find another sponsor and apply for a new job.\nOnce you receive a new job offer, your employer needs to provide you with a new Certificate of Sponsorship (CoS). You will then be able to apply for a new Tier 2 Visa and to remain in the UK until a decision is made.\nDo not forget that you can only accept job offers that meet the Resident Labour Market Test requirements. In addition, you are not allowed to start your new job until your Tier 2 Visa is issued.\nSwitching to a new visa after your Tier 2 curtailment\nDepending on your circumstances, you may have different options to remain in the UK. In other words, you may be eligible for a different visa.\nFor example, if one of your relatives is a British citizen or settled person, you can apply for a Family Visa. Otherwise, if you have a genuine idea for a new business, you can file a Tier 1 Entrepreneur Visa application.\nIf you have lived in the UK for at least 5 years on any lawful immigration status, you may also be eligible for ILR. The Indefinite Leave to Remain will grant you the right to live, work, and settle in the UK without being subject to immigration control.\nThe Tier 2 Visa “cooling off period”\nIf you are unable to apply for a new permit after your Tier 2 Visa curtailment, you have to leave the UK. Otherwise, you will face severe consequences and jeopardise your chances to be granted re-admission in the country.\nOnce outside the UK, you can still apply for a new Tier 2 Visa. However, you will be allowed to submit your application only after twelve months or more have passed since you left the country. This is known as the Tier 2 Visa “cooling off period”.\nIf you plan to apply for a new Work Visa, you must keep any evidence of leaving the UK, such as your airline tickets, to show when this period started. Nevertheless, if you wish to apply for a different visa category, you are free to do that without having to wait for the cooling off period.\nCan I appeal against a Tier 2 Visa curtailment letter?\nAfter the Home Office has been informed of your employment termination, you will receive a Tier 2 Visa curtailment letter. This document discloses your rights and duties, including details about your entitlement to challenge this decision. However, the Home Office hardly grants the right to appeal against a Tier 2 Visa curtailment. By losing your employment status, you do not satisfy the minimum requirements for this permit anymore.\nAs there is rarely a different option, you will need to either seek new employment or leave the country.\nOn the other hand, it is unlikely for the Home Office to impose an immediate termination of your leave to remain. It is worth noting that your employment contract is binding on both parties, and you are entitled to a minimum notice period. In other words, you still have time to apply for a new visa or to adequately arrange for your return to your home country.\nWhat happens if my Tier 2 Sponsorship is cancelled?\nIf your company loses its licence, your Tier 2 Visa can no longer be sponsored. As a consequence, your immigration status will be automatically cancelled.\nIt must be noted that there is no appeal option in this instance. Without a proper Sponsor Licence, your Tier 2 Visa cannot be considered valid anymore. However, you will still be given 60 days to either leave the country or get a new visa.\nIf you received a Tier 2 Visa curtailment letter, you must ensure to follow the right steps. By doing this, you can maintain a lawful immigration status and get a better chance of having another UK Visa granted in the future.", "pred_label": "__label__POS", "pred_score_pos": 0.6726670861244202}
{"content": "Lipoprotein (a) (Lp(a)) is a plasma lipoprotein of high atherogenicity and competes with plasminogen at the site of plasminogen receptors. It is known that diabetic patients show a hypercoagulable state which might contribute to diabetic vascular complications. In the present study, mean levels of plasma Lp(a) and parameters of coagulation and fibrinolysis such as thrombin-antithrombin III complex (TAT) and alpha 2 plasmin inhibitor-plasmin complex (alpha 2PIC) were elevated in diabetic patients with nephropathy compared to healthy controls. A significant positive correlation was observed between the plasma levels of Lp(a) and alpha 2PIC (p < 0.05). Plasma levels of alpha 2PIC showed a significant positive correlation with those of TAT in the diabetic group, while there was no significant correlation observed in the non-diabetic group. The present results suggest that factors of Lp(a) and coagulation-fibrinolytic systems interacted, contributing to vascular complications in diabetic patients with nephropathy.", "pred_label": "__label__POS", "pred_score_pos": 0.9985694289207458}
{"content": "Abstract\nBACKGROUND: Fear of death (FoD) is an exceptionally stressful symptom of ST-elevation myocardial infarction (STEMI), which received little scientific attention in recent years. We aimed to describe the prevalence and factors contributing to FoD among STEMI patients and assess the impact of FoD on prehospital delay.\nMETHODS: This investigation was based on 592 STEMI patients who participated in the Munich Examination of Delay in Patients Experiencing Acute Myocardial Infarction (MEDEA) study. Data on sociodemographic, clinical and psycho-behavioral characteristics were collected at bedside. Multivariate logistic regression models were used to identify factors associated with FoD.\nRESULTS: A total of 15% of STEMI patients reported FoD (n = 88), no significant gender difference was found. STEMI pain strength [OR = 2.3 (1.4-3.9)], STEMI symptom severity [OR = 3.7 (2-6.8)], risk perception pre-STEMI [OR = 1.9 (1.2-3.2)] and negative affectivity [OR = 1.9 (1.2-3.1)] were independently associated with FoD. The median delay for those who experienced FoD was 139 min compared to 218 min for those who did not (p = 0.005). Male patients with FoD were significantly more likely to delay less than 120 min [OR = 2.11(1.25-3.57); p = 0.005], whereas in women, this association was not significant. Additionally, a clear dose-response relationship between fear severity and delay was observed. Male FoD patients significantly more often used emergency services to reach the hospital (p = 0.003).\nCONCLUSIONS: FoD is experienced by a clinically meaningful minority of vulnerable STEMI patients and is strongly associated with shorter delay times in men but not in women. Patients' uses of emergency services play an important role in reducing the delay in male FoD patients.", "pred_label": "__label__POS", "pred_score_pos": 0.9852814078330994}
{"content": "Common Sense Parenting (CSP) is a parenting program that can be applied to every family.\nThe program's easy-to-learn techniques address issues of communication, discipline, decision making, relationships, self-control and school success.\nCommon Sense Parenting classes help parents:\nBuild strong, healthy relationships Correct and change problem behavior Minimize problems that disrupt family life Raise responsible, caring children Communicate effectively Avoid power struggles Control your emotions Balance discipline with affection Praise a childu2019s good behavior\nProfessionally trained parent trainers teach the course band provide instruction, consultation band support.\nEarly studies examined CSP results based on parent and family characteristics. Results indicated improvement in child behavior, parent attitudes, family satisfaction and parent problem-solving ability. Additionally, CSP participants reported statistically and clinically significant reductions in child behavior problems that were maintained at a three-month follow-up.\nA recent evaluation of CSP was completed as part of a research project and in collaboration with the Center for At-Risk Childrenu2019s Services at the University of Nebraska-Lincoln. Participants, many with significant risk factors, were referred to the CSP program through various sources. Results revealed statistically significant increases in positive parenting beliefs and practices, and reductions in parenting stress and parent-reported child behavior problems.", "pred_label": "__label__POS", "pred_score_pos": 0.5837763547897339}
{"content": "March 27, 2020\nMayo Clinic is investigating infrapatellar saphenous nerve neuroma as a source of pain after total knee arthroplasty. About 20% of patients who have a total knee arthroplasty are dissatisfied with the result, often due to residual pain. Mayo Clinic's work seeks to address persistent medial knee pain that lacks a clear etiology, such as infection, misalignment or loosening of the prosthesis.\n\"This type of medial pain can be misdiagnosed as tendonitis or pes anserine bursitis. But it often turns out to be an infrapatellar saphenous nerve neuroma that is causing pain,\" says Glenn G. Shi, M.D., an orthopedic surgeon at Mayo Clinic in Jacksonville, Florida. \"Patients who have a misdiagnosis might be sent to pain clinics or physical therapy with no reasonable outcomes. That leads to a lot of frustration for patients and orthopedic surgeons alike.\"\nThe incidence of infrapatellar saphenous nerve neuroma after total knee replacement is unknown. \"But we think this problem is underrecognized,\" Dr. Shi says.\nRama infrarrotuliana del nervio safeno\nLa ilustración muestra la rama infrarrotuliana del nervio safeno, que suele cortarse durante una artroplastia total de rodilla.\nIn cadaveric studies, Mayo Clinic has found that the standard surgical incision used in total knee arthroplasty almost always severs the infrapatellar saphenous nerve. The severed nerve generally doesn't affect the knee's function. But the nerve ending can become trapped in the incision's closure or in subsequent scar tissue, leading to a neuroma.\n\"Why some people get a neuroma and others don't is part of our investigation,\" Dr. Shi says. \"We are also trying to determine if we can somehow tuck the nerve end into the knee during surgery, to protect it from entrapment and prevent problems down the road.\"\nSeeking a modified surgical technique\nMayo Clinic's investigation of saphenous nerve neuroma after total knee arthroplasty encompasses several studies. The cadaveric project aims not only to understand the anatomical pattern of the nerve's intersection with a standard knee-replacement incision but also to investigate suturing techniques that avoid trapping the nerve in the incision closure. Clinical studies assess how frequently orthopedic surgeons see the saphenous nerve during standard total knee arthroplasty. \"If we can teach our orthopedic surgeons to see the nerve, we can potentially avoid injury that might require another surgery,\" Dr. Shi says.\nIn addition, Mayo Clinic is investigating strategies to treat infrapatellar saphenous nerve neuroma. One approach involves ultrasound-guided hydrodissection of the nerve from the adjacent interfascial planes, followed by a corticosteroid injection. A preliminary Mayo Clinic study found that this minimally invasive procedure significantly reduced medial knee pain for nine of 16 patients studied.\nFor patients whose pain persists after hydrodissection, Mayo Clinic is exploring options for surgical repair. \"We are trying to use a less invasive incision to find the nerve end and place it in an area where it is protected from scar tissue,\" Dr. Shi says. A prospective study is using a similar approach during total knee arthroplasty to prevent infrapatellar saphenous nerve neuroma from developing.\n\"This problem isn't widely discussed among orthopedic surgeons, but it's very impactful. Up to 3 million people are expected to have total knee arthroplasty by 2035,\" Dr. Shi says. \"Our goal is to bring attention to this problem, which we think contributes to patients' dissatisfaction after total knee arthroplasty. A modified technique for the procedure can potentially avoid the development of neuroma and reduce pain.\"", "pred_label": "__label__POS", "pred_score_pos": 0.6894118785858154}
{"content": "The Consumer Financial Protection Bureau released an outline of proposed regulations aimed at strengthening debt collection rules. The first effort to significantly govern debt collection in 40 years, the outlined proposal provides the first public glimpse of how the CFPB is planning to move forward in the debt collection rulemaking process. According to\nThe New York Times, under the proposed regulations, debt collection companies will have to more fully document the debt they are trying to collect, make it clear how a consumer can dispute the debt, and adhere to state statutes of limitations that bar them from pursuing older debts. Additionally, collectors would be barred from trying to contact individuals who owe money more than 6 times per week, and after a debtor dies, collectors would have to wait 30 days before contacting family members about paying up. Although the proposals only cover third-party debt collection issues, the CFPB also indicated that it plans to address outstanding issues such as first-party debt collectors and creditors at a later date.\nThe number of Americans filing new applications for jobless benefits rose more than expected last week. Initial claims for unemployment benefits, a proxy for layoffs across the U.S., rose by 14,000 to a seasonally adjusted 266,000 in the week ended July 23, according to the Labor Department. However, according to The Wall Street Journal, economists believe the underlying trend continues to point to sustained labor market strength.\nChina’s Cabinet issued its first rules for ride-sharing apps, encouraging local officials to promote the burgeoning industry, and affirming the legal status of Uber and local competitors. After years of tension with regulators, including office raids by Chinese police and legal challenges to their business model, Uber and its Chinese competitors welcomed the official endorsement. The Cabinet set guidelines for registration, fares, employment of drivers and payments, but is giving cities and local authorities leeway to work with the industry across the country.", "pred_label": "__label__POS", "pred_score_pos": 0.8170440196990967}
{"content": "It’s no secret it costs a premium to live within a specific school zone. But how much?\nNew Real Estate Institute of Victoria (REIV) data shows that homes located within the catchment area for some of Melbourne’s best public secondary schools are attracting close to a $600,000 premium compared to those outside the zone.\nIn 2016, the median house price of properties with more than two bedrooms in desirable public school zones is significantly higher than the median price of nearby similar homes bordering the zone.\nTop of the class? The analysis, undertaken in the 12 months to March, shows the largest price difference was recorded for homes zoned for University High in inner northern Parkville.\nHomes within the school zone had a median house price of $1,395,000 while homes within a one-kilometre radius of the school zone had a median of $799,000 – a difference of $596,000.\nHomes zoned for McKinnon Secondary College also achieved sale prices significantly higher than those located outside the catchment area. The median house price for homes within the zone was $1,500,000 compared to a median of $1,195,000 for homes in the same suburb but outside the school zone.\nVendors of homes within the school zone for Cheltenham Secondary College could also expect higher sale prices than those located outside the zone. A difference of $150,000 was recorded for homes that sold within the school zone.\nREIV CEO Geoff White says access to high-quality amenities and services – particularly schooling and education – is a key driver of price growth across Melbourne.\n“Rather than paying private school fees, parents of school-aged children are increasingly investing that money in the family home and buying into areas zoned for top performing public schools,” he says.\n“These areas also experience a high number of sales indicating the level of buyer demand within these zones.”\nArticle source: http://feedproxy.google.com/~r/API_Property_News/~3/VbmROcyekOY/", "pred_label": "__label__POS", "pred_score_pos": 0.5776733160018921}
{"content": "Anxiety disorders are the most common mental illness in the USA, affecting 40 million adults. Now, during the pandemic, anxiety levels have only increased: fear of going out, grocery shopping, taking…\nTag:\npositive psychology\nAll managers would like their teams to be more productive. Yet most companies are using the same old methods: strategic plans, goal-setting, streamlining operations, reducing inefficiency. Others are offering employee…", "pred_label": "__label__POS", "pred_score_pos": 0.6846047639846802}
{"content": "From this compact book, learn from a certified financial planner certificant CFP® who has helped hundreds of clients over more than thirty-five years practical estate planning steps you can take to protect yourself and those you love. This book, written in layperson’s words for easy understanding, explains aspects of wills, financial and medical powers of attorney, revocable living trusts, “living wills,” and much more. Learn how to use free tools such as beneficiary designations, POD, and TOD forms (and when not to use them) to avoid the expense, delay, and publicity of probate. Making distinctions among single ownership, joint ownership with rights of survivorship, and trust ownership are essential.\nThis work explains personal retirement plans such as traditional and Roth IRAs, 401(k), and 403(b) employer retirement plans, along with concepts such as tax deferral, pretax, and after-tax contributions, transfers, and retirement plan distribution strategies. Income taxes, capital gain taxes, and estate taxes are also made simple. Michael shows you how to maintain control over your team of advisors while getting the most out of professionals who serve you. Having been a caregiver himself, learn from Michael how you can successfully navigate emotional concerns, preventing and reducing family arguments. Challenges faced by spouses, parents, adult children, caregivers, executors and administrators, heirs, and beneficiaries are highlighted to lighten your burden. Michael’s experience and education provide valuable insights for widows, widowers, and adult children suffering from the pain and fog of bereavement. This unique book combines both helpful tips to solve thorny obstacles you face, without confusing legalese, with an understanding of the feelings individuals and families face on the path from wellness, to illness, death, and while tackling postdeath estate settlement. This book fills a crucial unmet need enabling spouses, parents, and adult children to make wiser decisions while protecting those they love.", "pred_label": "__label__POS", "pred_score_pos": 0.8754739761352539}
{"content": "Neodrill, known for its industry-leading CAN technology, has launched its new Wellhead Saver System. Designed to directly address the industry challenge of drift-off, it is estimated that the new solution will deliver savings in the order of 6 to 12 rig days on a typical well. Enhanced health and safety benefits are also a key part of the technology.\nWhen deepwater rigs are used under shallow water conditions, the forces and bending moments from the BOP and riser are placed on the wellhead. The new WSS adapts the established CAN well foundation to redirect the bending forces away from the wellhead directly into the well foundation. By protecting the wellhead, conductor and casing from over-bending and over-stressing, it is possible to increase the drift-off distance before disconnect occurs. This allows the rig to stay on location and remain connected to the well in more severe weather conditions, saving idle rig time costs.\nCompared to the traditional approach of tethering the BOP and wellhead system down, the WSS is connected to both the wellhead and the CAN, which allows it to act as a wellhead saver sub. This process enables drilling operations to take place without loading the original wellhead. It also facilitates installation of the production tree on a virgin wellhead. Compared to the BOP tethering system, a unique aspect is that it avoids long steel and fibre wires that may require re-tensioning during operations.\nIt is anticipated that the WSS will deliver cost savings and HSE benefits. The use of the CAN technology, as well as the reduced weight of the system in comparison to the BOP tethering system, also reduces the CO\n2 footprint.\nNeodrill’s Chief Executive Officer, Jostein Aleksandersen says, “With the increased use of deepwater drilling rigs in shallow water operations, the underlying threat of ‘drift-off’ will increase substantially. Our Wellhead Saver System has been designed to overcome the challenges typically associated with the use of heavy BOPs on deepwater rigs in shallow water.”\n“Sitting as part of our new solutions offering, the WSS looks to bring a smart solution to the market to effect real positive change,” Aleksandersen continues.", "pred_label": "__label__POS", "pred_score_pos": 0.6013721227645874}
{"content": "He stated: “Pubs are just starting to get back on their feet after lockdown and these new restrictions are a significant setback.”\n“We urgently need the Government to extend the furlough scheme for hospitality venues and confirm what additional support it will provide to protect jobs and the future of pubs.\n“We made safety our priority when reopening and fewer than one per cent of our 1,700 managed pubs have been contacted by NHS Test and Trace since reopening in July, which demonstrates pubs are not disproportionately spreading cases and our measures are working.\n“Removing a key trading period and further damaging customer confidence looks set to cost us several million pounds per week, on top of already reduced customer numbers in our pubs to maintain social distancing.", "pred_label": "__label__POS", "pred_score_pos": 0.9143757820129395}
{"content": "Maintaining the integrity of the pharmaceutical supply chain in this unprecedented time would not be possible without the incredible efforts of distribution industry employees, who are working around-the-clock to move critical medicines and healthcare supplies.\nSupporting and protecting valued employees is a core mission for HDA distributor members. This crisis has forced the industry to be nimble and think creatively about how best to protect the health and wellness of employees while ensuring they have the flexibility and resources they need to work effectively.\nPlanning and Preparation\nMaintaining a robust employee support system during a once-in-a-lifetime public health challenge begins with preparation. As news of the virus began to spread earlier this year, distributors sprang into action, proactively launching contingency plans to stay ahead of the curve. Many HDA members convened company-wide task forces and initiatives to coordinate their individual responses, ensure the continued operations of critical business functions and put procedures in place to keep employees safe.\nAs part of ongoing efforts to provide additional resources for members and augment their individual response efforts, HDA organized and distributed recommended protocols on maintaining a safe working environment during COVID-19, including key recommendations from the Centers for Disease Control and Prevention (CDC) and Occupational Safety and Health Administration (OSHA). The protocols were recently updated as individuals and businesses adapt to the “new normal” of operating under a pandemic.\nAdditionally, each distributor member has their own plan in place for how operations will adjust if an employee tests positive for COVID-19. This may include shutting down a facility for 24 hours for a deep cleaning before reopening for business or activating contingency protocols that rely on nearby distribution centers to continue processing orders if one facility is closed.\nProtocols for a Safe Work Environment\nWhile HDA members quickly transitioned staff that could work remotely, sustaining pharmaceutical supply chain operations requires that many pharmaceutical distribution center staff remain on site to organize and ship products.\nFollowing the outbreak, distributors instituted a variety of preventive measures in accordance with CDC guidelines and implemented new programs designed to protect and recognize employees’ contributions during this unprecedented time. Each HDA member company has individual procedures in place that reflect their unique workforce. Some examples of programs and policies include:\nMandating daily deep cleanings at all distribution centers and hiring additional cleaning staff to more frequently sterilize public surfaces to further minimize risk. Changing guidelines to allow employees to avoid high-traffic areas, including encouraging employees to “punch in” using a time clock app on their phones and staggering lunch breaks. Dividing staff into shifts and paying one shift to stay at home and remain on call in case someone on the main shift tests positive for COVID-19. Distributing personal protective equipment (PPE) to employees and couriers. Supporting employees through incentive pay, back-up dependent care programs and enhanced paid time off policies for those who need to quarantine or care for family members. Providing lunches for employees to support nearby restaurants and minimize trips away from facilities during shifts.\nThroughout this crisis, HDA distributor members have gone the extra mile to direct lifesaving medicines to the frontlines while meeting the daily healthcare needs of all Americans. This has only been possible by protecting the health and well-being of their people.\nTo learn more about the industry’s commitment to ensuring the health and wellness of distributor employees and their families, check out our new video.\nFor additional HDA materials and pandemic response resources, visit: www.hda.org/covid19.", "pred_label": "__label__POS", "pred_score_pos": 0.5923793315887451}
{"content": "Dayton Ohio is a smaller, lower-density, and slow-growing metropolitan area, not a prime expansion candidate for venture-capital backed private mobility providers. The local transit agency took a need for bikeshare into its own hands, partnering with a local nonprofit, Bike Miami Valley, to bring Link Dayton Bikeshare to the region. This arrangement is unique in that the transit agency is the owner and operator of the service. When dockless scooters swept the country in 2019, the Regional Transit Agency (RTA) applied the same agency-operated and -maintained model to a partnership with the scooter provider Spin — a model that’s unique among transit agencies in the U.S. This gave the agency facility over managing multiple modes, partnering with providers, and understanding major data issues at play. APTA describes the experience in a feature on Transit as a Micromobility Manager.\nWhen the City of Dayton was working on authorizing legislation for scooters, the RTA worked closely with them to require that any provider permitted to operate in the city must provide a public API and integrate with the City’s chosen mobility app provider. Now, Dayton is working with the Transit app on trip planning integration, and RTA and Bike Miami Valley have included similar language in their transportation and bikeshare contracts, requiring all private transportation providers (ridehailing, scooters, micromobility, and whatever comes next) to aggregate their service information alongside RTA’s schedule in a single trip planner as a condition of operating in the city. Working with a private provider provides the city and transit agency with a system that’s agnostic both to the services and the platform providers and lets the public agencies maintain continuity even if they choose to change vendors in future.\nIn 2019 Uber began offering transit trip planning on its app, and by May it launched a partnership with Denver’s Regional Transportation District (RTD) and its mobile ticketing partner Masabi. Now, Uber riders in Denver can both see real-time transit information in the app, and have the ability to purchase tickets and use their phones to access ridehail and bus services. Denver was the first city globally to have such an option through the Uber app. Uber is not the only option for mobile ticketing, and by working with a flexible vendor, Denver has multiple channels available for users to purchase and use tickets online. In Las Vegas, where an entrepreneur had previously tried and failed to develop a subscription-based MaaS platform with Tesla vehicles, a similar partnership enables ticketing on the Uber app. Each of these examples demonstrates advancement towards Level 2 of MaaS.", "pred_label": "__label__POS", "pred_score_pos": 0.5852913856506348}
{"content": "Litigation Lawyers in Lancaster\nResidents of Lancaster, Wisconsin who suffer legal wrongs are typically legally entitled to compensation for harm they incurred as a result. This compensation is typically obtained by filing a lawsuit.\nIf you're contemplating filing a lawsuit, there are various things you need to consider, and it is not a decision to be made lightly. You should not file a lawsuit without seeking the advice of a Lancaster, Wisconsin civil litigation attorney first.\nYour Lancaster, Wisconsin civil litigation attorney will be able to advise you on whether or not you have a legitimate case, and, if so, your best avenues on how to proceed. The attorney will also discuss with you the fees for their services, and whether he or she can represent you on a contingency basis.\nSteps for Filing a Lawsuit in Lancaster, Wisconsin\nConsultation with your attorney: Before you proceed with any legal action in Lancaster, Wisconsin, you should seek the advice and counsel of a reliable Lancaster, Wisconsin attorney. He or she will be indispensable in helping you succeed in your lawsuit.\nDrafting The Complaint: In Lancaster, Wisconsin, the initial step to filing a lawsuit, once you've actually decided to do so (in consultation with your attorney), is writing a complaint. A complaint is simply a list of facts that you allege against the defendant. A court must look at these allegations and decide if they add up to a legitimate cause of action, assuming they're true. If they do not add up to a cause of action, the case may be dismissed. The complaint also typically ask the court to provide specific relief, should it rule in the plaintiff's favor.\nServing The Defendant: Once you and your attorney have written a good complaint, and filed it with the court, it needs to be served on the defendant within a specific period of time. This is necessary under the law of Lancaster, Wisconsin to ensure that the defendant actually knows that he's being sued, and has time to find a lawyer and prepare a defense. Generally, the defendant should be served in person. However, when this isn't possible, service by mail is also acceptable in a few instances.\nAwaiting the Defendant's Response: Once a lawsuit has been filed, and the defendant has been served in Lancaster, Wisconsin, the defendant has time to respond. They typically do so by drafting an answer to the complaint, in which they deny the plaintiff's allegations, or assert a legal defense. If the defendant fails to respond within a set period of time, they will be in default, and you may be able to get a \"default judgment\" against them, in which all of your allegations against the defendant are viewed as if the defendant admitted them, and you only need to establish that you've suffered losses that warrant the damages you're asking for.\nHow Can A Lancaster, Wisconsin Tort Lawyer Help?\nThe basic outline above does not come close to covering all the specifics involved in filing a lawsuit in Lancaster, Wisconsin.\nIf you have suffered a legal wrong in and decide to sue the person who you believed wronged you, you should speak with a qualified Lancaster, Wisconsin attorney.", "pred_label": "__label__POS", "pred_score_pos": 0.9383171200752258}
{"content": "FDA Issues Guidelines on Safe Development of Nanotechnology Products\nThe agency issued three final guidances and one draft guidance to provide regulatory clarity for industry on the use of nanotechnology.\nThe U.S. Food and Drug Administration has issued three final guidances and one draft guidance on the use of nanotechnology in manufacturing in order to provide greater \"regulatory clarity\" for the industry, according to a press release from the agency. One final guidance covers the agency's overall approach for the products being regulated and the other two final guidances and the draft guidance provide recommendations for food, cosmetics, and food for animals.\n\"Our goal remains to ensure transparent and predictable regulatory pathways, grounded in the best available science, in support of the responsible development of nanotechnology products,\" said FDA Commissioner Dr. Margaret A. Hamburg. \"We are taking a prudent scientific approach to assess each product on its own merits and are not making broad, general assumptions about the safety of nanotechnology products.\"\nFDA points out it does not \"make a categorical judgment that nanotechnology is inherently safe or harmful, and will continue to consider the specific characteristics of individual products.\" Nanotechnology is an emerging technology that allows scientists to create and manipulate materials on an incredibly small scale measured in nanometers.\nAccording to the FDA, the guidances are:\nFinal Guidance for Industry: Considering Whether an FDA-Regulated Product Involves the Application of Nanotechnology\nThe guidance outlines overarching considerations for all FDA-regulated products, identifying points to consider when determining whether a product involves the use of nanotechnology. It is intended to help industry and others identify when they should consider potential implications for regulatory status, safety, effectiveness or public health impact that may arise with the application of nanotechnology in FDA-regulated products.Final Guidance for Industry: Safety of Nanomaterials in Cosmetics\nThe guidance describes FDA's current thinking on the safety assessment of nanomaterials when used in cosmetic products and encourages manufacturers to consult with the FDA on test methods and data needed to support the substantiation of a product’s safety.\nFinal Guidance for Industry: Assessing the Effects of Significant Manufacturing Process Changes, Including Emerging Technologies, on the Safety and Regulatory Status of Food Ingredients and Food Contact Substances, Including Food Ingredients that are Color Additives\nThe guidance alerts manufacturers to the potential impact of any significant manufacturing process change, including changes involving nanotechnology, on the safety and regulatory status of food substances. This guidance also describes considerations for determining whether a significant manufacturing process change for a food substance already in the market affects the identity, safety, or regulatory status of the food substance, potentially warranting a regulatory submission to the FDA.\nDraft Guidance for Industry: Use of Nanomaterials in Food for Animals\nThis draft guidance addresses issues related to the use of nanotechnology in food ingredients intended for use in food for animals. Public comments on this draft guidance are requested by Sept. 10, 2014.\nFDA will continue to pursue ongoing scientific research and regulatory efforts and will consider new studies and data, as they become available, to determine future actions. Science is a critical component of the agency’s ongoing review of products. FDA has invested in a nanotechnology regulatory science program that will enhance the agency's scientific capabilities. Additional guidance for industry will be developed as needed.\nFDA, an agency within the U.S. Department of Health and Human Services, protects the public health by assuring the safety, effectiveness, and security of human and veterinary drugs, vaccines, and other biological products for human use, and medical devices.", "pred_label": "__label__POS", "pred_score_pos": 0.620331883430481}
{"content": "Abstract:\nProtracted volcanic eruptions may exhibit unanticipated intensifications in explosive behaviour and attendant hazards. Santiaguito dome complex, Guatemala, has been characterised by century-long effusion interspersed with frequent, small-to-moderate (<2 km high plumes) gas-and-ash explosions. During 2015–2016, explosions intensified generating hazardous ash-rich plumes (up to 7 km high) and pyroclastic flows. Here, we integrate petrological, geochemical and geophysical evidence to evaluate the causes of explosion intensification. Seismic and infrasound signals reveal progressively longer repose intervals between explosions and deeper fragmentation levels as the seismic energy of these events increased by up to four orders of magnitude. Evidence from geothermobarometry, bulk geochemistry and groundmass microlite textures reveal that the onset of large explosions was concordant with a relatively fast ascent of a deeper-sourced (∼17–24 km), higher temperature (∼960–1020◦C) and relatively volatile-rich magma compared to the previous erupted lavas, which stalled at ∼2 km depth and mingled with the left-over mush that resided beneath the pre-2015 lava dome. ... mehrWe interpret that purging driven by the injection of this deep-sourced magma disrupted the long-term activity, driving a transition from low energy shallow shear-driven fragmentation, to high energy deeper overpressure-driven fragmentation that excavated significant portions of the conduit and intensified local volcanic hazards. Our findings demonstrate the value of multi-parametric approaches for understanding volcanic processes and the triggers for enigmatic shifts in eruption style, with the detection of vicissitudes in both monitoring signals and petrological signatures of the eruptive products proving paramount.", "pred_label": "__label__POS", "pred_score_pos": 0.8708086609840393}
{"content": "Object: The predominant mechanism of early graft failure after coronary artery bypass grafting (CABG) is associated with antiplatelet treatment using drugs such as acetylsalicylic acid (ASA). Impaired hemostasis of multiple etiologies is often present in patients undergoing on-pump cardiac surgery. We investigated the impact of intravenous ASA administration on platelet function in this setting. Methods: Forty-two patients were enrolled in the study. Patients received 100 mg oral ASA once daily, beginning in the early postoperative period. Noncompliance was eliminated by the administration of 300 mg ASA intravenously at 6-8 days post-operation. Blood was drawn immediately before, 1 h and 24 h after ASA administration. Results: A platelet function analyzer (PFA-100™) was used to evaluate closure time (CT), turbidimetric platelet aggregation (TPA) and impedance platelet aggregation (IPA) induced by arachidonic acid (AA), collagen and ADP and results were compared with the respective values from 120 healthy individuals. At 1 h and 24 h after administration, we found that intravenous ASA caused CEPI-CT to be significantly prolonged with a reduction of AA and collagen-induced IPA. Despite postoperative oral ASA administration for 6-8 days, PFA-100™ CEPI and CADP-CT were significantly shorter and ADP-TPA and IPA values induced by any agonist were significantly greater in patients than in controls. Intravenous ASA had no significant influence on CADP-CT or ADP-induced IPA (ADP-IPA). Conclusion: Platelet tests for diagnosing patients as aspirin responders (ASA-R) or aspirin non-responders (ASA-NR) were found to be not comparable. Patients after CABG show augmented platelet dysfunction. Intravenous ASA administration may indicate a promising approach to reduce laboratory resistance after CABG procedure. The reason for this is not clear and requires additional clinical studies.\n© Georg Thieme Verlag KG Stuttgart · New York.", "pred_label": "__label__POS", "pred_score_pos": 0.6271640658378601}
{"content": "Abstract Motivation Phylogenetic networks represent reticulate evolutionary histories. Statistical methods for their inference under the multispecies coalescent have recently been developed. A particularly powerful approach uses data that consist of bi-allelic markers (e.g., single nucleotide polymorphism data) and allows for exact likelihood computations of phylogenetic networks while numerically integrating over all possible gene trees per marker. While the approach has good accuracy in terms of estimating the network and its parameters, likelihood computations remain a major computational bottleneck and limit the method’s applicability. Results In this paper, we first demonstrate why likelihood computations of networks take orders of magnitude more time when compared to trees. We then propose an approach for inference of phylo-genetic networks based on pseudo-likelihood using bi-allelic markers. We demonstrate the scalability and accuracy of phylogenetic network inference via pseudo-likelihood computations on simulated data. Furthermore, we demonstrate aspects of robustness of the method to violations in the underlying assumptions of the employed statistical model. Finally, we demonstrate the application of the method to biological data. The proposed method allows for analyzing larger data sets in terms of the numbers of taxa and reticulation events. While pseudo-likelihood had been proposed before for data consisting of gene trees, the work here uses sequence data directly, offering several advantages as we discuss. Availability The methods have been implemented in PhyloNet (http://bioinfocs.rice.edu/phylonet). Contact ,", "pred_label": "__label__POS", "pred_score_pos": 0.6300244927406311}
{"content": "Many large companies work in both the commercial and government sectors. However, when large companies do business with the government, they often unintentionally overlook whether the focus of their brand’s message resonates with the government sector. While marketing campaigns and branding may be working very successfully with target commercial markets, the same messaging and campaigns may fall short of achieving the goal of raising awareness and perceptions of the company within the target government market, because government decision-makers’ needs, priorities and expectations can vary widely from what motivates commercial buyers.\nBrand and perception studies, or\nAttitude, Awareness and Usage (AAU) research, can provide government contractors invaluable insights into how they are perceived in the government marketplace, revealing gaps in market understanding and acceptance of your brand. This can make a significant difference in everything from general market positioning to win themes in specific bids and proposals. Conducting this type of research specifically for the government market. Be sure to read the full article on how contractors can better leverage brand studies to remain competitive in today’s austere budget climate here.", "pred_label": "__label__POS", "pred_score_pos": 0.798693060874939}
{"content": "First Nations are being asked to develop tendering policies as a condition of funding related to federal funded capital projects over $100,000, excluding housing. This requirement for a competitive tendering process is intended to support public confidence in the transfer of federal funds to First Nations and in their accountability.\nFirst Nation tendering policies should address the local situation and aspirations of their communities, but they must encompass the key principles and mechanisms applied by the public and private sectors. This document is intended to assist First Nations in developing their own tendering policies.", "pred_label": "__label__POS", "pred_score_pos": 0.9853302240371704}
{"content": "I remember vividly the first time I taught a class. It was the summer of 1992 at the Universidad Laboral in Gijón, Asturias, as part of the Spanish Language and Cultural Studies Program hosted for European students by Universidad de Oviedo. The anticipation and anxiety I felt then still reverberate in my practices today. First day of school will always be an exhilarating event for me!\nAs I was preparing to meet my students at Saint Petersburg Polytechnical University (SPbPU), my mind was racing to the speed of sound and my heart was pounding: would I be able to connect with their hearts? would the material I curated for them with such care be appealing? how would I manage to engage every learner in our conversations?\nmatices, it felt familiar. It was time. I timidly entered the room and felt observed with curiosity, certainly did not perceive a sign of reservation, and I went on: ‘hello, my name is Nuria, we will be working together this semester exploring matters of intercultural literacy, language identity and storytelling. It is an honor to be here with you, and look forward to learning from your perspectives and creating together a space where all views and opinions are welcome and respected. I want to heartily thank you for this opportunity. Now, please, tell me about yourselves…”\nand with this prelude, SPbPU students began to share insights about their lives and their dreams, some with more confidence than others, but all with an elegant cadence in the way they uttered the English sentences. I was captivated. They are linguists and study several languages, they have a deep appreciation for language diversity and understand that the world does not end at the Russian borders. They are willing to examine their own cultural beliefs in light of new perspectives, they are courageous. I feel fortunate to have such inspiring teachers!", "pred_label": "__label__POS", "pred_score_pos": 0.8605372905731201}
{"content": "Sanctions have long been a serious concern for banks. However, they are now being applied more regularly across a variety of industries. Breaking them can quickly lead to heavy fines, export bans, denial of access to the US banking system, reputational damage, and severe supply chain disruption. Individuals involved risk criminal charges.\nRecent portfolio\nA selection of articles, reports and other content.\nArchives\nNovember 2020\nCategories", "pred_label": "__label__POS", "pred_score_pos": 0.5076302289962769}
{"content": "UC Merced A histone deacetylase adjusts transcription kinetics at coding sequences during Candida albicans morphogenesis. Author(s): Hnisz, Denes Bardet, Anaïs F Nobile, Clarissa J Petryshyn, Andriy Glaser, Walter Schöck, Ulrike Stark, Alexander Kuchler, Karl et al. Published Web Locationhttps://doi.org/10.1371/journal.pgen.1003118 Abstract\nDespite their classical role as transcriptional repressors, several histone deacetylases, including the baker's yeast Set3/Hos2 complex (Set3C), facilitate gene expression. In the dimorphic human pathogen Candida albicans, the homologue of the Set3C inhibits the yeast-to-filament transition, but the precise molecular details of this function have remained elusive. Here, we use a combination of ChIP-Seq and RNA-Seq to show that the Set3C acts as a transcriptional co-factor of metabolic and morphogenesis-related genes in C. albicans. Binding of the Set3C correlates with gene expression during fungal morphogenesis; yet, surprisingly, deletion of SET3 leaves the steady-state expression level of most genes unchanged, both during exponential yeast-phase growth and during the yeast-filament transition. Fine temporal resolution of transcription in cells undergoing this transition revealed that the Set3C modulates transient expression changes of key morphogenesis-related genes. These include a transcription factor cluster comprising of NRG1, EFG1, BRG1, and TEC1, which form a regulatory circuit controlling hyphal differentiation. Set3C appears to restrict the factors by modulating their transcription kinetics, and the hyperfilamentous phenotype of SET3-deficient cells can be reverted by mutating the circuit factors. These results indicate that the chromatin status at coding regions represents a dynamic platform influencing transcription kinetics. Moreover, we suggest that transcription at the coding sequence can be transiently decoupled from potentially conflicting promoter information in dynamic environments.", "pred_label": "__label__POS", "pred_score_pos": 0.936760663986206}
{"content": "Covid-19 Impacts on Immigration Detention: Global Responses\nOver the past few months, immigration detention practices around the world have been changing rapidly as state and civil society actors respond to manage the multiple impacts of COVID-19. In some cases, these changes have been positive, leading to stronger protection of the rights of non-citizens. In others, they have led to the increased marginalisation of and discrimination against non-citizens.\nIn collaborating with the Humanitarian and Development Research Initiative to produce this joint edited collection, IDC sought to provide a platform for our members and partners to discuss their experiences, actions and perspectives as the pandemic unfolded across the globe. The contributions are rich and diverse, showing the impact that COVID-19 has had on refugee, undocumented migrant and stateless communities around the world.", "pred_label": "__label__POS", "pred_score_pos": 0.5702095031738281}
{"content": "This article explores the Spanish crown's efforts to study, cultivate, and transplant spices from the East Indies to the West Indies and then to Spain in the sixteenth and early seventeenth centuries. Beginning with Christopher Columbus's first observations of New World flora, the Spanish crown sought out spices to cultivate for economic gain. Although they were ultimately unsuccessful in efforts to generate a large-scale spice trade, colonial officials and local entrepreneurs participated in a coordinated program of empirical information gathering and botanical experimentation that is itself of historical significance. For the empirical and experimental—\"scientific\"—methods they represented serve to challenge and enhance current understanding of several historiographical themes: the origins of economic botany and the Scientific Revolution more generally, the role of human agency in the Columbian exchange, and the dissemination of knowledge from imperial centers to colonial peripheries.", "pred_label": "__label__POS", "pred_score_pos": 0.6064866781234741}
{"content": "To ensure the most economically vulnerable residents in the state are supported during a state of emergency, the Senate advanced legislation on Thursday and it now heads to the Governor’s desk.\nThe bill (A-3858) would require the Commissioner of Human Services to issue supplemental cash assistance payments, under certain circumstances, to those within the Work First New Jersey program, the Supplemental Nutrition Assistance Program, and the special supplemental food program for women, infants and children.\nThe bill sponsors, Assembly Democrats Raj Mukherji (D-Hudson), William Spearman (D-Camden, Gloucester) and Andrew Zwicker (D-Somerset, Mercer, Middlesex, Hunterdon), issued the following statement:\n“Food shortages caused by COVID-19 could have a devastating impact on families who rely on public assistance programs to put food on the table. Too many living paycheck to paycheck are grappling with what do if they are unable to afford extra stocks of food and basic supplies at home. Making sure these families, in times of special vulnerability like a pandemic, have the extra financial support they need is both critical and just.”\nThe bill was approved by the full Assembly 53-0-12 on Monday March 16, 2020.", "pred_label": "__label__POS", "pred_score_pos": 0.5032467842102051}
{"content": "Livestock producers can now access a wealth of industry information collected from the 2016 beef and sheep industry in a new pocket-sized yearbook produced by AHDB Beef & Lamb.\nFacts and figures have been compiled and updated to deliver key insights for industry from farm-to-fork.\nBeef and veal exports were up ten per cent on 2015 at more than 110,000 tonnes, giving a return of £370 million to the beef sector. However, issues around supplies, competitiveness and consumer demand have played a significant part in driving up prices.\nFor the sheep sector, prices remained below average until May. June’s referendum led to a sharp decline in the value of the pound and consumer demand came under pressure due to rising retail prices and competitively priced alternatives such as chicken.\nDuncan Wyatt, lead red meat analyst at AHDB, said: “The pocketbook provides essential information to our levy payers and stakeholders, helping them make informed decisions about their businesses.\n“Having an insight into recent market trends ensures the industry is better prepared for what is to come. This is even more important with Brexit on the horizon, as levy payer businesses need to ensure they are equipped to deal with the potential impact this may have.”\nThe yearbook can be downloaded from the AHDB Beef & Lamb website or a hard copy requested by emailing beeflamb.comms@ahdb.org.uk", "pred_label": "__label__POS", "pred_score_pos": 0.634867250919342}
{"content": "With many students across the country participating in virtual learning during the COVID-19 pandemic, at-school vision screenings have been limited. These annual school-provided screenings play a crucial role in identifying and treating vision problems early on. While this adversely affects all students, those from low-income families are particularly disadvantaged. Dr. Joel Leffler, Pediatrix-affiliated pediatric ophthalmologist at Children’s Eye Care of North Texas in Plano, says parents who struggle more with economic hardship often lack access to these basic health examinations, even in pre-COVID times. “It is safe to assume that these at-risk children have even less access to essential services like vision screenings and assessments during the pandemic, as availability of health and community services are even more limited,” Leffler said.\nView the full story at Healthline", "pred_label": "__label__POS", "pred_score_pos": 0.8423799276351929}
{"content": "Signs of Child Abuse\nChild abuse does not discriminate. It happens in every culture, class, and community. It might be happening to your child or affecting your child’s best friend or teammate. When you notice one or more of these signs, you may be unsure if abuse is occurring. Children may exhibit these signs but not be victims, or they may be victims without clearly identifiable signs. If you suspect abuse, you should think critically about what else you know or have observed about the family.\nIf you have a concern about a child from a different culture than your own or who belongs to a community that you don’t understand well, consider whether the concern relates to parenting practices and personal beliefs that may be different from your own, but are not necessarily abuse. Remember, families struggling with poverty are often safe and loving. Thank you for your care in understanding how to detect abuse. Your actions today are part of the solution.", "pred_label": "__label__POS", "pred_score_pos": 0.6396908760070801}
{"content": "Many people in the United States spend a significant portion of their income on housing, which leaves less for other essentials such as food and transportation. What options are available for those who are seeking more affordable housing? How can the church support them?\nWhether you avail yourself of a single session on a topic that interests you, or engage in an ongoing basis, linking your faith with your approach to contemporary issues should prove rewarding.", "pred_label": "__label__POS", "pred_score_pos": 1.0000087022781372}
{"content": "CREATE VIBRANT COMMUNITIES\nCommunity revitalization is about holistically creating healthier communities. Research consistently shows that access to affordable housing is crucial for vital communities and there are positive impacts between housing and the social well being of residents.\nThis section provides resources that address varying aspects of community revitalization, including tools to engage residents in housing and community-led regeneration initiatives.\nResources can be found under the following key themes:", "pred_label": "__label__POS", "pred_score_pos": 1.000003457069397}
{"content": "The journey for foster and adopted children, their caregivers, and the supportive professionals can seem like a runaway train at times. This journey is often filled with heart-warming connection and heart-wrenching pain (often at the same time) and this ambiguity and volatily can often create crisis for all parties involved. How each party understands and relates to moments of crisis is the number one factor in how well we get through it gracefully with the least amount of “collateral damage.” This 2-part webinar series will take a closer look at crisis so we can perhaps not only better navigate it but also prevent unnecessary crisis.\nYou are here: / / Crisis Intervention Part I: Managing Aggression and Other Difficult Behaviors", "pred_label": "__label__POS", "pred_score_pos": 0.9758835434913635}
{"content": "As a renter, you don't want anything that brings harm to you or your possessions. However, sometimes, things happen that are beyond your control. For example, a fire might break out and destroy your property. Even if you took steps to reduce fire risks, they clearly didn't completely eliminate the risk of one occurring.\nIt's certainly important to take fire safety precautions as a renter. However, you also need protection in the event that a blaze breaks out anyway. This is where a comprehensive renters insurance policy can help.\nRenters Insurance and Fire Coverage\nRenters insurance often comes with two standard types of coverage — liability and personal property coverage. Liability coverage can help protect renters if their actions lead to unintentional injuries or property damage. For example, let's say you accidentally knock over a candle that causes a fire and substantial property damage. Liability coverage may help you compensate the property owners for the damages to their owned property. The owner or landlord's insurance may also cover fire damage.\nPersonal Property coverage can help renters protect damage to their own personal property. As a renter, you likely own most or all the possessions inside of the rental home. By placing a value on your possessions in your policy, you can help replace these items should a fire destroy them.\nMost renters don't have to worry about how to repair property damage or replace personal items after a fire. Their renters insurance policy should help. Nonetheless, every policy differs, and some might exclude certain fire damage scenarios. Renters should ensure that they have the right fire coverage for their specific property.\nProper Fire Prevention Steps in Rental Properties\nWhen you rent a home, you should often consider yourself a guardian of another person's property. You should do everything you can to reduce fire risks. This can protect both you and the property owner.\nBefore moving in, make sure the homeowner has had the home inspected by a third party to ensure it meets fire code.\nIf you notice frayed wiring, damaged electrical systems, clogged chimneys or other fire risks, tell the homeowner. They will need to have someone repair the damage.\nUse all electrical appliances in the home appropriately. These are flammable systems, and should be treated with care. Only operate them according to manufacturer recommendations.\nMonitor your own usage of flammable materials, such as candles or heating irons. Never leave these items unattended.\nRemember, renters insurance will likely cover you for in the event of an accidental or uncontrollable fire. But you won't be covered if the fire was a result of negligence. Also, never set a fire on purpose. This act is considered arson. And arson is felony crime in most states,\nincluding Minnesota.\nWe can help you find coverage. Call\nLancette Agency, LLC at (651) 264-1230 for a free Minnesota renters insurance quote.", "pred_label": "__label__POS", "pred_score_pos": 0.9170435070991516}
{"content": "SMEs don't understand security risks, ACSC survey finds\nEach year cyber incidents cost this cohort a combined $29 billion, yet nearly half of them cannot or will not invest more than $500 per annum on cybersecurity.\nA general lack of awareness and understanding of IT is largely to blame.\nOf more than 1700 people surveyed, nearly one in 10 were unable to explain cyber threat terminology such as malware, phishing, ransomware or insider threats. One in five Mac users were unaware of which operating system their business was using, while the same proportion of Windows users have an operating system that stopped receiving security updates in January 2020.\nAdditionally, there was an apparent reluctance to invest in cybersecurity, with the majority of respondents underestimating the damage a cyber attack could cause. Around 87% believed they could regain normal operations immediately or within a few days following an attack.\nSole traders were the least prepared with just 3% outsourcing their own cybersecurity, compared with 35% of higher-staffed SMEs. Those who were outsourcing their IT overestimated the level of protection it provided.\nDespite underestimating the risk, 90% of respondents are seeking to further their understanding and better manage cybersecurity threats.\nMany blame complexity and a lack of dedicated IT staff for their current practice.\nImage credit: ©stock.adobe.com/au/MIND AND I\nThe ACCC is seeking feedback about Google's proposed acquisition of Fitbit, and an...\nThe Privacy Act 2020 is now in effect in New Zealand, with changes that will affect businesses...\nCybermerc has announced the launch of a government-funded national cyber threat sharing platform...", "pred_label": "__label__POS", "pred_score_pos": 0.9758538007736206}
{"content": "Taxing Caloric Sweetened Beverages: Potential Effects on Beverage Consumption, Calorie Intake, and Obesity The link between high U.S. obesity rates and the overconsumption of added sugars, largely from sodas and fruit drinks, has prompted public calls for a tax on caloric sweetened beverages. Faced with such a tax, consumers may reduce consumption of these sweetened beverages and substitute nontaxed beverages, such as bottled water, juice, and milk. This study estimated that a tax-induced 20-percent price increase on caloric sweetened beverages could cause an average reduction of 37 calories per day, or 3.8 pounds of body weight over a year, for adults and an average of 43 calories per day, or 4.5 pounds over a year, for children. Given these reductions in calorie consumption, results show an estimated decline in adult overweight prevalence (66.9 to 62.4 percent) and obesity prevalence (33.4 to 30.4 percent), as well as the child at-risk-for-overweight prevalence (32.3 to 27.0 percent) and the overweight prevalence (16.6 to 13.7 percent).\nActual impacts would depend on many factors, including how the tax is reflected in consumer prices and the competitive strategies of beverage manufacturers and food retailers.\nReleased Friday, July 2, 2010\nSee http://www.ers.usda.gov/Publications/ERR100/", "pred_label": "__label__POS", "pred_score_pos": 0.5852042436599731}
{"content": "Nutrition\nIn early 2016, Mondelez introduced its updated ‘Strategy Globe’ and formulated a vision, ‘to be the best snacking company in the world.’ To achieve its vision and strategic focus, Mondelez has identified three growth ambitions: Grow our people, grow our business and grow our impact. In this context, it has developed a new platform, ‘Impact for Growth’ which the company sees as a focused approach to driving growth and delivering positive change.\nMondelez factors nutrition into its decisions about acquisitions. The company also conducts extensive nutrition-related risk assessment to mitigate risks to support its ‘Well-being Strategy.’ This type of risk assessment is one of the most comprehensive from the companies assessed.\nDespite some strong elements described above, the company could strengthen its commitment to grow by making nutrition and health more central in its ‘Strategy Globe’ and by having it play a more integral and central role in its ‘growth ambitions.’ This should be built upon a clear commitment to deliver more, healthy foods with specific reference to low-income populations in both developed and developing markets.\n‘Impact for Growth’ covers Mondelez’ global ‘Well-being Strategy’ which has three pillars: 1. Expanding ten existing well-being brands in Mondelez portfolio, with the goal of growing them at twice the rate of its base portfolio; 2. Renovating and improving the nutrition and ingredient profile of its best-selling brand; 3. Continuing to inspire consumers to snack mindfully and planning to deliver 15% of its revenue from portion-controlled snacks that are individually wrapped and have 200 calories or fewer.\nWithin these three pillars, Mondelez has formulated additional 2020 goals covering a broad range of nutrition-related topics such as product reformulation, developing its healthy product portfolio, labeling, marketing to children, consumer education and stakeholder engagement.\nMondelez’s CEO, in conjunction with a Board Committee, is engaged in the review and progress of its ‘Well-being Strategy.’ The company has established a ‘Well-being Leadership Team’ that is overseen by three senior executives who report directly to the Board and the CEO. The ‘Well-being Leadership Team’ sets the direction of Mondelez global ‘Well-being Strategy.’ Even though the CEO’s accountability for the overall business strategy of which the ‘Well-being Strategy’ is an important component, Mondelez could strengthen this commitment by linking directly the remuneration of its CEO to its well-being objectives.\nTo strengthen its ‘Well-being Strategy’, the company is encouraged to conduct annual internal audits of its delivery. It could also expand the formal panel that advises the Board with specialists from a broader range of expertise, such as marketing, labeling and promoting active lifestyles.\nThe company annually publishes a progress report entitled, The Impact for Growth, and provides global updates on nutrition. Despite its global presence, the company does not publish separate reports for its major markets. Mondelez also does not yet follow the industry-leading practice of commissioning external verification of the nutrition information and data in its reports.", "pred_label": "__label__POS", "pred_score_pos": 0.8861046433448792}
{"content": "Abstract\nObjective: To investigate the association between 25-hydroxyvitamin D [25(OH)D] levels prior to liver transplantation (LT) and the development of acute cellular rejection (ACR) within the first year post LT.Methods: This retrospective study included 275 consecutive LTs performed in 262 patients at Mayo Clinic in Jacksonville, Florida over 13 months. A total of 149 patients met the inclusion criteria. The correlations between 25(OH)D levels and the development, severity, and number of biopsy-proven ACR episodes were assessed.Results: The prevalence of 25(OH)D levels <30 ng/mL was 92%. No association was found between pre LT 25(OH)D levels and the diagnosis of ACR (P = .61). Mean ± SD pre LT 25(OH)D levels were 16.1 ± 6.8 ng/mL for 48 subjects with no rejection, 16.1 ± 8.2 ng/mL for those with a mild first episode of ACR (n = 58), and 18.4 ± 12.4 ng/mL for those who experienced a moderate/severe first ACR (n = 39). However, in a subgroup analysis of patients with 25(OH)D levels <30 ng/mL, there was a statistically significant negative correlation (P = .0252) between 25(OH) D level and the ACR rate.Conclusion: Vitamin D insufficiency and deficiency prior to LT was prevalent in our cohort. There was no statistically significant association between low 25(OH)D levels and the diagnosis or severity of ACR or the number of rejection episodes within the first year post LT. However, there was a negative correlation between 25(OH)D levels below 30 ng/mL and the rate of ACR within 1 year post LT.\nASJC Scopus subject areas Endocrinology, Diabetes and Metabolism Endocrinology", "pred_label": "__label__POS", "pred_score_pos": 0.5679439306259155}
{"content": "You are currently viewing the abstract.View Full Text\nLog in to view the full text\nAAAS login provides access to\nScience for AAAS members, and access to other journals in the Science family to users who have purchased individual subscriptions. Log in through your institution Log in through your institution Abstract\nEngagement of the interleukin-17 (IL-17) receptor complex triggers activation of the transcription factor nuclear factor κB (NF-κB). A wide array of signaling molecules can contribute to the activation of NF-κB, but a number of common themes link the receptors engaged to activate it with the translocation of the active complex to the nucleus; among these is a clear role for ubiquitination. Ubiquitination is essential to the degradation of the inhibitor of NF-κB (IκB) subunits, which otherwise retain the inactive NF-κB complex in the cytosol. However, additional roles for ubiquitination in the assembly of signaling complexes and in enzyme activation are underappreciated aspects of NF-κB induction pathways. These roles require a form of ubiquitination biochemically distinct from that which targets proteins for degradation. The identification of Act1, an adaptor protein of the IL-17 receptor, as an E3 ubiquitin ligase capable of initiating this modification provides an impressive connection between the IL-17 receptor complex and pathways that activate NF-κB.", "pred_label": "__label__POS", "pred_score_pos": 0.6591246128082275}
{"content": "Announcement\nThe teams from ECMC North successfullly delivered their first online educational event on 19 October 2020. We have now moved to developing the content for the ECMC COVID-19 Community Hub, a curated online platform to build on the learnings from the workshops held in October.\nWondering what other centres do to overcome the challenges of COVID-19 for early phase trials? Interested in contributing to sharing best practice? Don’t know who to ask about COVID-19 implications when planning future trials? Then join ECMC North in the educational event to help develop a framework for delivery during the pandemic.\nBelow are two examples of work being done in Manchester to support the COVID effort.\nBy David Pinato et al. published in Cancer Discovery.\nA large Imperial-led study has revealed valuable insights into the impact and risk factors for cancer patients with COVID-19. The findings, from almost 900 cancer patients diagnosed with SARS-CoV-2 infection in the UK, Spain, Italy and Germany, highlight a number of key clinical insights, including:\nThe CATALYST trial is seeking signals of efficacy of drugs targeting the most serious symptoms of the COVID virus. The aim is to reduce the severity of the disease, leading to a reduction in the number of patients needing to be admitted to intensive care, and ultimately in deaths. The drugs being tested include those already in use for patients with cancer and inflammatory diseases such as rheumatoid arthritis.\nCancer Research UK has collated some of the guidelines from official sources on the collection and processing of human specimens for clinical and translational research during and after the COVID-19 pandemic into a single document.\nUCLH is part of the Oxford COVID-19 vaccine trial and expected to recruit 500 participants in June.\nStaff at Cardiff's ECMC have been transferring their talents to help tackle the pandemic, engaging in the rapid set-up and recruitment to COVID-related studies.", "pred_label": "__label__POS", "pred_score_pos": 0.6567374467849731}
{"content": "When hitting the roads this fall you should always drive with confidence especially when the temperatures and weather conditions drastically change. In a year filled with so much uncertainty, the last problem you need is a broken-down car. We can't say it enough but proper tune-ups will ensure your vehicle lasts longer while preventing costly repairs that may result from neglect. Forgetting to tune up your car or truck after your summer travel can be a costly one. At Naugatuck River Motors we prioritize your needs while keeping your pocket in mind. Our goal has always been to keep Connecticut drivers on the road longer while ensuring their vehicle is safe and reliable. No matter the issue, our skilled mechanics and technicians will take care of you; rest assured you're in the right hands. With nearly four decades of experience, our mechanics will diagnose and repair any issues before they progress. Proper tune-ups are essential, and we’re ready to keep your car or truck top of mind! Should I Take My Car or Truck in For a Tune-Up? Of course, no matter the age or type of vehicle you should always prioritize regular maintenance for your weekend cruiser or everyday car. Not only does a proper tune-up ensure your vehicle is safe, but it reduces associated costs that could arise down the road. This is especially the case for basic fluid changes that are the vital components to a fully functional car. Neglect them, and face the consequences of a damaged engine, transmission, or faulty brakes. Contact our mechanics to see if you're due for a tune-up and save! What do Mechanics Check During Tune-Ups? A qualified mechanic will take a diverse approach to vehicle inspection. When having regular maintenance checks in fixed intervals, your car or truck will receive first-class treatment at Naugatuck River Motors. We know that your vehicle is a large investment and we want to ensure the value of your vehicle performs better than the industry average for your model. What are some of the routine tune-ups performed? Fluid Changes Air condition fluid, transmission fluid, antifreeze, and brake fluid are essential to the longevity of your vehicle. When replacing these fluids in a timely manner you can rest knowing your car is safe to drive. Air Filters Not only do air filters pass the necessary airflow to your vehicle but they prevent your vehicle from using more gas. In a time of economic uncertainty, your dollars shouldn't be spent on fill-ups. During each tune-up, our Waterbury mechanics will inspect each air filter for excessive debris, while ensuring your car's air filters run properly. Don't let your car stall from lack of oxygen. Whenever recommended, replace your air filters to avoid unfavorable outcomes. Windshield Wipers As temperatures begin to change and the weather begins to be even more unpredictable, all Connecticut vehicle owners should have their windshield wipers inspected and replaced. Worn-out windshield wipers just won't do the job and can result in an accident when driving in inclement weather. Car Battery Although car batteries are made to last a significant amount of time, you should always have a mechanic inspect your battery to ensure it is properly connected and all looks well. Oil Changes Vehicles typically need a regular oil change every three to six months. but this may vary due to driving habits. Oil is highly important in the functions of your vehicle as it carries away heat from your engine. Running on old oil and failing to properly drain it could result in engine issues and in severe cases, permanent damage. Contact our team for a low-cost oil change in Connecticut. Belts During a tune-up, a skilled auto mechanic will inspect and diagnose all your vehicle's hoses and belts. This is especially vital for older vehicles that tend to wear out hoses and belts far quicker. If you hear any unusual noises coming from your vehicle you should inform us immediately. This may be due to a faulty or worn-out belt that needs to be replaced. For classic car owners, hoses can frequently get clogged resulting in costly repairs. Our mechanics will inspect each hose properly to ensure there is no splitting or cracked hoses. If needed, we will replace any worn-out hoses. Does Regular Maintenance Improve the Value of my Vehicle? Neglect is the biggest deterrent to any prospective buyer. Forgetting to have regular maintenance and inspections will result in a vehicle that depreciates rapidly. Not only will your vehicle be susceptible to breakdowns but the value of your vehicle will go with it. No one wants another person's problems, especially when it comes to vehicles. Leading Auto Facility in Waterbury, Connecticut As a top-rated auto facility in Waterbury, Connecticut we understand the importance of traditional tune-ups for your vehicle. When you arrive at Naugatuck River Motors we want you to understand that we have built a history of quality service at affordable rates. We know what our competitors offer, and to them, you're just another dollar sign. This is not the case with Naugatuck River Motors, we take pride in exceptional customer service and offer a clear and concise diagnosis of any vehicle issue. Contact our team today to see how you can save on your first maintenance check-up. Naugatuckrivermotors.com | 203-527-6494", "pred_label": "__label__POS", "pred_score_pos": 0.6453378200531006}
{"content": "Third-Party Advocates Will Play a Key Role in a New Political Dynamic\nBy: Jared Parks, Vice President\nTo put it mildly, 2020 has not been a year that has been short on surprises and challenges. The first global pandemic in a century which demanded robust policy responses, coupled with a highly-charged and often unpredictable political environment – and a looming election – presented enormous challenges for businesses of every shape and size and across diverse industries. Those businesses and industries also faced unprecedented challenges in advocating for their principals and interests in a virtual environment where constituents and advocates could no longer engage as easily with policymakers and their staffs through shoe-leather lobbying or traditional constituent meetings.\nIn this context, 2020 has underscored the importance of partnering with like-minded third-party advocacy organizations to ensure that policymakers and staff hear stakeholders’ key messages and fully understand the impacts of a given policy consideration upon them. Third-party groups can be a voice for the often large numbers of grassroots activists among their memberships, offering lawmakers a finger on the pulse of their constituents when direct engagement is more difficult. They also often have a deep well of policy expertise which they can offer to policymakers on the basis of trusted, well-established relationships. Finally, many third-party groups have well-developed relationships with the media and can be valuable allies in getting a message out and shaping a narrative.\nLooking ahead to 2021, and with the election now behind us, there are still many unknowns ahead, but it is clear that we will have a new presidential administration and a divided government should the current Senate majority remain in-tact. It is equally clear that third parties will have a critical role to play across the board in the new dynamic awaiting us in 2021.\nThe incoming administration will confront the immediate task of staffing up at every agency across government. Many third-party policy experts and advocates bring their expertise to bear in government service when ideologically aligned with the administration in power. If past is precedent, the new administration will draw heavily upon the deep bench of policy experts and advocates at like-minded think tanks and third-party groups as they look to fill key roles. This makes aligned third-party groups a valuable resource to a new administration, effective influencers with key personnel, and powerful advocacy partners.\nAdditionally, third-party groups often serve not just as advocates, but as incubators for policy proposals ranging from taxes to infrastructure to energy. As any new administration seeks to hit the ground running in implementing its agenda, it can draw upon the expertise, research, and recommendations of aligned third parties that have often spent years studying a given issue, making such organizations valuable partners in engaging and educating a new crop of policymakers.\nFor the outgoing administration and presumed Republican majority in the Senate, third parties are more important than ever. Many from the outgoing administration will likely apply their expertise, experience, and relationships as outside advocates at aligned third-party groups. And for Republican lawmakers seeking to restore and expand their party’s position in government, support from allied third parties and the vast numbers of conservative activists they represent is critical to their success.\nAt The Herald Group, our Alliance Development team focuses solely on building and maintaining extensive relationships with national, state, and local third-party groups and key opinion leaders and works to mobilize these organizations and influencers on behalf of our clients. THG’s strategic partnership building capabilities include:\nThird-Party Audits and Platform Development Coalition Strategy and Development Identification, Recruitment, and Mobilization of Key Third-Party Advocates Key Influencer Communications\nIn a year that has brought many changes to the advocacy space, the importance of leveraging third-party partnerships has been a constant, and at The Herald Group, we only see its value increasing in the months ahead.", "pred_label": "__label__POS", "pred_score_pos": 0.618141770362854}
{"content": "We are excited to be participating in AWS re:Invent 2017, the largest global conference focused on cloud computing. As a company, if you’re thinking of, or already have embarked on a cloud initiative, this is a must attend event.\nFrom Backup to Analytics – Hybrid Cloud Redefined\nCompanies of all sizes are being faced with the explosion of data and are struggling on how to effectively manage it and extract value from it. This has been one of the key drivers of the great migration to the cloud. As traditional File, Block, SAN and NAS environments cannot cost effectively scale with this rapid data growth, nor are they architected to support unstructured data, companies are looking at object storage and cloud to provide a viable solution.\nObject storage is the backbone of all major cloud providers and allows scalability, data durability and resiliency not achievable with traditional RAID architectures. Object is the language of the Cloud and S3 / Object APIs are becoming the norm. Customizable metadata and search capabilities enhance data value.\nNew hybrid workflows, leveraging object storage on premises with public cloud resources, are changing the economics of data for analytics and backup workloads. At re:Invent we’ll be showcasing how our HGST ActiveScale™ object storage system enables hybrid workflows that can greatly simplify backup environments while increasing storage efficiency to deliver dramatic savings.\nAn Ecosystem to Power Your Hybrid Cloud Strategy – Booth #127\nWe have a built a deep ecosystem of vertically integrated Independent Software Vendors (ISVs) that can help companies determine their appropriate cloud strategy and improve hybrid workflow data management. At AWS re:Invent 2017 several key ISVs will join us in our\nbooth #127, including: StorReduce– Rethink Your Backup Strategy: StorReduce is the only deduplication engine built for cloud object storage. StorReduce is designed to meet the unique requirements of companies using public, private or hybrid cloud storage for large volumes of data. StorReduce sits between your applications and cloud storage, transparently deduplicating data inline at speeds of up to 1400 MB/s per server, reducing storage costs, speeding up the time for transfer between clouds and freeing your data for use in the cloud via standard cloud APIs. Learn how StorReduce + HGST’s ActiveScale + AWS™ can replace traditional backup appliances, saving you 70%+. Primary Data – Intelligently Automate Data Management:Primary Data’s DataSphere gives petabyte-scale enterprises the ability to respond automatically to the demands of their applications and data. Whether IT needs to optimize performance, simplify data migrations, save budget, or simplify adoption of new technologies like the cloud, DataSphere makes it simple to set objectives and automate data management across existing and new storage resources. Elastifile™– enjoy a data anywhere strategy:As a cloud-scale distributed file system, on-premises and in-cloud, Elastifile’s data fabric is seamlessly accessible from anywhere in the world, allowing users to integrate and collaborate with the data as if it’s stored locally. With flash-native, scale-out performance, every workload’s data is now available to use without needing to ask for it, wait for it, or copy it across the network. Join Us at AWS re:Invent 2017\nOur expertise in manufacturing up the stack, starting at the hard disk drive components, delivers you with industry leading reliability, significant cost efficiencies to help enable a data forever architecture.\nBe sure to stop by the\nVenetian/Sands Expo Hall, Booth #127 to learn more about how HGST ActiveScale system, paired with AWS and our ISV partners, can help your data thrive while saving you and your company money.\nI look forward to seeing you in Las Vegas!", "pred_label": "__label__POS", "pred_score_pos": 0.6598851084709167}
{"content": "The Central Agency for Public Mobilization and Statistics (CAPMAS) announced, on Monday, that Egypt’s unemployment rate rose slightly to 9.6% during the second quarter (Q2) of 2020.\nThe latest figures reflect a slight increase of 1.9% compared to the 7.7% reported in Q1 of 2020, and an increase of 2.1% from Q2 of 2019.\nCAPMAS noted that the number of unemployed reached 2,574 million, or 9.6%, of the total workforce, of which 1,934 million were male and 640,000 were female. This compared to the 2,236 million unemployed in Q1 of 2020, reflecting a 15.1% increase to 338,000. This also reflected an increase of 480,000 from Q2 of 2019, or a 22.9% uptick.\nCAPMAS attributed this rise in the country’s unemployment rate to the repercussions of the novel coronavirus (COVID-19) pandemic.\nThe government-implemented precautionary measures that saw schools and international air traffic suspended, as well as the partial closure of shops, and public transportation closed during a night-time curfew, were just some of the measures that have affected the local economy.\nMohamed Abo Basha, Head of Macroeconomic Analysis at EFG Hermes Holding, told Daily News Egypt, that the latest unemployment figures are not a large hike in comparison to other countries in America and Europe.\nHe added that other countries have witnessed higher hikes in unemployment rates, as they had to impose tougher lockdown measures due to the pandemic than Egypt.\n“Egypt did not impose a total closure, but rather a partial closure with a curfew, which resulted in a relatively small increase in its unemployment rate,” he said, “Additionally, some sectors, including construction, industry, and agriculture, have not been affected largely, while the most affected sectors were the services sector, so this results in an unemployment hike which is not as large as that which was witnessed in other countries.”\nCAPMAS explained that the size of Egypt’s workforce reached 26,689 million employees during Q2 of 2020, compared to 29,008 million employees during Q1, reflecting a decrease of 8.0%. The agency pointed out that the urban labour force reached 11,817 million individuals, while in the countryside it reached 14,872 million individuals. Egypt’s male labour force currently stands at 22,746 million, whilst the female workforce stands at 3,943 million.\nCAPMAS noted that the decline in workforce numbers can be attributed to the pandemic, which has lead to both job losses, and a general dip in job opportunities.\nThe agency explained that, of the proportion of men in the workforce, 8.5% were unemployed in Q2 of 2020, compared to 4.5% in Q1, and 4.2% in Q2 of 2019. The unemployment rate among female was 16.2% of the total female labour force in Q2 of 2020, compared to 21.9% in Q1 of the year, and 22.4% in Q2 of 2019.\nThe agency added that, during Q2 of 2020, the percentage of unemployed in the 15 to 29 years age group reached 60.4%, compared to 68.5% in Q1.\nThe percentage of unemployed in the 15-29 years age group reached 60.4% of the total unemployed, while 39.7% of the total unemployed were recorded in the 30-64 years age group.\nThe agency explained that the urban unemployment rate reached 12.5% during Q2 of 2020, compared to 11.1% in Q1, and 9.3% in Q2 of 2019. At the same time, the unemployment rate in rural areas reached 7.4%, compared to 5.1% in Q1, and 6.1% in Q2 of 2019.\nCAPMAS added that the percentage of unemployed people with intermediate, upper-intermediate, university degrees and postgraduate degrees decreased to 69.2% in Q2 of 2020, compared to 85.0% in Q1.\nThe number of employed individuals reached 24,115 million in Q2 of 2020, compared to 26,772 million in Q1, a decrease of 9.9%. The urban work force reached 10,339 million workers, while it scored 13,776 million in rural areas.\nCAPMAS explained that the number of workers receiving cash wages reached 18,306 million, or 75.9% of the total employed, of which 15,782 million are male and 2,524 million are female.\nThe number of self-employed workers reached 2,091 million, of which 2,027 million are male and 64,000 are female, representing 8.7% of the total employed.\nThe agency added that the number of self-employed workers who do not employ others has reached 2,662 million, of whom 2,438 million are male workers and 224,000 are female. This segment represents 11.0% of the total.\nThe number of workers contributing to unpaid work, or projects within the family, reached 1,056 million workers. Of this, 565,000 were male and 491,000 were female, representing 4.4% of the total employed.\nThe agency indicated that the wholesale and retail trade activity lost 624,000 workers during Q2 of 2020, whilst manufacturing activity lost 569,000 workers. Food and accommodation services activities lost 469,000 workers, the transport and storage activity lost 309,000 workers, and the construction and building activity lost 288,000 employees.\nAccording to CAPMAS, agricultural and fishing activity achieved the largest participation rate of workers in economic activities, as the number of workers in this sector reached 5,053 million. Of this number, 4,513 million were male and 540,000 were female, representing 21.0% of the total employed.\nThe number of workers in Egypt’s construction sector reached 3,364 million workers, of whom 3,343 million were male and 21,000 were female, or 14.0% of the total number. The number of workers in wholesale and retail trade activity reached 3,240 million workers, of whom 2,901 million were male and 339,000 were female, or 13.4% of the total employed.\nThe number of workers in manufacturing activity reached 3,009 million, of which 2,810 million were male and 199,000 were female, representing 12.5% of the total employed. The number of workers in education reached 2,065 million, of which 1,065 million were male and 1 million were female, at 8.6% of the total employed.\nAbo Basha mentioned that it will take at least 12 months, if not longer, for Egypt’s employment rate to return to pre-coronavirus numbers. He stated that it depends on how the virus develops, and if there is a new wave or not.\n“As we have witnessed locally and globally, even if business movement returns and there is an increase in sales rates, the demand is not at the same levels as witnessed before COVID-19, which explains why most employers will be unable to take on new employees,” Abo Basha said\nAs an example of this, he highlighted Egypt’s tourism sector which remains far below its pre-coronavirus levels, despite the reopening of the country’s airports and hotels to local and international tourists.\nWith considerably less revenues coming in, hotels will be unable to take on new employees and, in turn, will not be able to operate with the same size of work force as pre-coronavirus. Abo Basha noted that that this low financial turnover and inability to take on new staff affects all other sectors in Egypt.\nHe added that the Egyptian economy may recover faster due the government not having imposed a complete lockdown. Despite some degree of economic activity permitted in the recent past, the local economy still faces uncertainty in the coming period, dependant on how the coronavirus develops.", "pred_label": "__label__POS", "pred_score_pos": 0.941179096698761}
{"content": "Youth in Ohio with complex behavioral health and multi-system needs face unique challenges and have unique care and support needs. Studies show that intensive community-based care coordination and the use of targeted in-home and community services that are driven by kids and their families can have a significant impact on inpatient and emergency department use, moves between homes, and other barriers to their ability to thrive. A different service array is needed to stabilize these children in their families.\nWith these needs in mind, the Ohio Department of Developmental Disabilities (DODD) is collaborating with the Ohio Department of Medicaid (ODM) to create OhioRISE (Resilience through Integrated Systems and Excellence), a specialized managed care plan that will serve this unique population’s needs.\nOn October 28, 2020, ODM released a Request for Applications (RFA) to solicit responses from managed care organizations (MCOs) interested in serving as the OhioRISE specialized managed care plan. Additional details and the RFA can be found on the Request for Proposals page of medicaid.ohio.gov.", "pred_label": "__label__POS", "pred_score_pos": 0.9395379424095154}
{"content": "Abstract\nObjective: To investigate the relationship between renal function and linezolid (LZD)-induced thrombocytopenia and elucidate the underlying mechanism using a chronic renal disease (CRD) mouse model. Materials and Methods: CRD was induced in 5-week-old male Institute of Cancer Research (ICR) mice by 5/6 nephrectomy. After this procedure, LZD (25 and 100 mg/kg) was administered intraperitoneally once every day for 28 days. Platelet counts, white blood cell (WBC) counts, and hematocrit (HCT) levels were measured every 7 days. 2-\n14C-thymidine (0.185 MBq) was administrated intravenously to LZD-administered mice to evaluate the thymidine uptake ability of bone marrow. Results: Platelet counts were significantly lower in the LZD-administered CRD group than in the LZD-nonadministered groups at 14, 21, and 28 days (P < 0.05); however, these changes were not observed in LZD-administered mice with normal renal function, regardless of the duration of LZD administration. No significant changes were observed in WBC counts or HCT levels in any LZD-administered CRD mouse. Moreover, radioactive levels in bone marrow were not significantly different in each group. Conclusions: These results indicate that LZD-induced decreases in platelet counts were enhanced by renal impairment in vivo, suggesting that LZD-induced thrombocytopenia is not caused by nonimmune-mediated bone marrow suppression. Keywords Chronic renal disease model mouse DNA synthesis ability hematological effect linezolid thrombocytopenia ASJC Scopus subject areas Pharmacology Pharmacology (medical)", "pred_label": "__label__POS", "pred_score_pos": 0.655410885810852}
{"content": "DOI:10.1128/MCB.11.1.468 ABSTRACT\nDuring Dictyostelium discoideum development, cell-cell communication is mediated through cyclic AMP (cAMP)-induced cAMP synthesis and secretion (cAMP signaling) and cell-cell contact. Cell-cell contact elicits cAMP secretion and modulates the magnitude of a subsequent cAMP signaling response (D. R. Fontana and P. L. Price, Differentiation 41:184-192, 1989), demonstrating that cell-cell contact and cAMP signaling are not independent events. To identify components involved in the contact-mediated modulation of cAMP signaling, amoebal membranes were added to aggregation-competent amoebae in suspension. The membranes from aggregation-competent amoebae inhibited cAMP signaling at all concentrations tested, while the membranes from vegetative amoebae exhibited a concentration-dependent enhancement or inhibition of cAMP signaling. Membrane lipids inhibited cAMP signaling at all concentrations tested. The lipids abolished cAMP signaling by blocking cAMP-induced adenylyl cyclase activation. The membrane lipids also inhibited amoeba-amoeba cohesion at concentrations comparable to those which inhibited cAMP signaling. The phospholipids and neutral lipids decreased cohesion and inhibited the cAMP signaling response. The glycolipid/sulfolipid fraction enhanced cohesion and cAMP signaling. Caffeine, a known inhibitor of cAMP-induced adenylyl cyclase activation, inhibited amoeba-amoeba cohesion. These studies demonstrate that endogenous lipids are capable of modulating amoeba-amoeba cohesion and cAMP-induced activation of the adenylyl cyclase. These results suggest that cohesion may modulate cAMP-induced adenylyl cyclase activation. Because the complete elimination of cohesion is accompanied by the complete elimination of cAMP signaling, these results further suggest that cohesion may be necessary for cAMP-induced adenylyl cyclase activation in D. discoideum.", "pred_label": "__label__POS", "pred_score_pos": 0.830378532409668}
{"content": "Preparation in early grades followed by a high school curriculum of high academic rigor is crucial to ensuring equal opportunity in the sciences at the college level and beyond. A lack of participation in STEM courses has been attributed to bias toward males in curricula (Sanders et al., 1997). Many students and their families don’t understand the benefits and requirements of taking increasingly high-level math courses starting in middle school. Providing this information to families often, early, and in the primary languages spoken in the homes is necessary. It is important that we don’t close opportunities to students from lack of understanding.\nA bias-free re-conceptualization of courses leading to nontraditional careers is necessary. Encouraging males to participate in allied health or early childhood education courses opens up opportunities that may have been of interest but felt off limits to the males. “Girls Math Camp” participants reported improved confidence when geometry lessons included drawing and manipulative models (Frost & Wiest, 2007). Respondents to a .html of 1000 female IT professionals named a relevant curriculum as one of four factors contributing to their entrance and persistence in an IT career (Girl Scouts, 2008). Curricular materials need to be relevant to a student’s prior experience (Zuga, 1999).\nWhen checking your curriculum for bias, pay attention to issues such as:\nstereotyping of the career or employees, invisibility of gender, ethnicity, and/or (dis)ability within the curriculum materials, restriction to a single viewpoint when many viewpoints exist, isolating “women’s contributions” or “inventions by African American scientists” to separating sections or indicating that they play but a minor role, and finally, using language that perpetuates the myth that only men are electricians or only women are teachers.\nA link to a more detailed curriculum checklist is included in the resources available to you at the end of this module and is available on www.napequity.org.", "pred_label": "__label__POS", "pred_score_pos": 0.6647392511367798}
{"content": "Wittgenstein noted that we engage in language games and quite often we borrow words from different games and misuse them such as using words with scientific connotations in religious discourse or using aesthetic terms in ethics and so on. He even claimed that mathematics was also suffering from the same problem, and he fiercely advocated for finitism as a result.\nHas anyone developed Wittgenstein's insight into techniques for discussing philosophical problems? Is it possible and if not why?\nFor me particularly in the field of theology, I often thank Wittgenstein for saving me from the theist/atheist debates that were really popular a few years ago. As a theist myself, l think we need to emphasize how much we don't understand God as he is unlike anything we know of, for starters He exists outside spacetime and when we use the word exist for him, it is clearly used in a different sense than any simple empirical statement in the world. Some theologians (Ibn Arabi) even differentiated existence into necessary and dependent existence to resolve the confusions that arise out of mixing these concepts up together. I believe that philosophy should always be focused on making things clear rather than building newer structures, but that's a topic for another day.", "pred_label": "__label__POS", "pred_score_pos": 0.9983630776405334}
{"content": "Fleet Operating Cost - Electric Trucks Goals\nTo determine the total cost of operating a fleet of electric vehicles by class (1 - 8).\nEarly Findings According to a report by Drive Electric, electric vehicles typically go 20 miles further than their gasoline counterparts for the same cost, translating into instant cost savings for electric vehicles. The primary costs of ownership of company vehicles in North America include depreciation (44%), fuel (22%), repairs and maintenance (17%), and interest, tax, and fees (5%), according to a report by Deloitte. The total cost of ownership of electric vehicles after accounting for depreciation and maintenance was found to be as low as $0.18 - $0.25 per mile, which is much lower than the $0.32 - $0.35 for standard sedans.\nInformation relating specifically to the total cost of operating a fleet of class 1 - 8 electric vehicles is scarce. This is mainly due to the fact that the market for electric trucks of any class is yet to mature, and few data exist on the history of their maintenance or durability to accurately estimate their total cost of operation. Below are some examples of companies that plan to launch class 1 - 8 trucks in the future:\nClass 1 - 4 Several automakers are set to begin production or introduce electric trucks in this category. Electric trucks from automakers such as Tesla, GM, Lordstown, Rivian, Ford, Bollinger, and Hercules are expected to hit the market between 2021 and 2024. Class 5 - 8 BYD, Volvo, and Freightliner are some of the major automakers that have announced their intention to produce or introduce electric trucks in this category in the nearest future. BYD is the global leader in battery-electric trucks. Although, it only began offering electric trucks to the public in October 2019. It currently offers class 5 and class 6 trucks. Freightliner introduced pre-production models in August 2019 to gauge the feasibility of heavy-duty electric trucks and further refine the finished product with insights obtained from the operations of the pre-production models. Proposed next steps:\nYou need to be the project owner to select a next step.", "pred_label": "__label__POS", "pred_score_pos": 0.7901833653450012}
{"content": "Fleet managers should collaborate with a procurement contract specialists and the company's legal department to review commercial terms of a contract.\nDifferentiating Sourcing and Strategic Sourcing From Purchasing and Procurement\nOne challenge for fleet managers interacting with procurement professionals is understanding the nuances of procurement terminology. Many fleet managers believe the term “procurement” is synonymous with the term “sourcing,” but there are important distinctions between the two functions.", "pred_label": "__label__POS", "pred_score_pos": 0.8096331357955933}
{"content": "Cybercriminals are well-funded, organized and increasingly sophisticated, leveraging dark web chat forums and government-grade software tools. The targeting of financial institutions is on the rise. These cyberthreat statistics must be taken seriously; financial institutions need a plan to stay ahead of the attacks.\nDuring this 56-second video we’ll answer the following questions:", "pred_label": "__label__POS", "pred_score_pos": 0.9932302832603455}
{"content": "March 2020\nIZA DP No. 13065: Parents' Responses to Teacher Qualifications\nWe identify the causal effect of teacher qualifications on parents' investments in their children. Exploiting a unique, high-stakes educational setting in which teachers are randomly assigned to classes, we show that parents react to more qualified teachers by increasing their financial investments in their children. The key mechanism is an increase in parents' belief that academic achievement is driven by student effort—for which financial investment is instrumental. However, higher teacher qualifications do not improve student test scores. This is likely due to a negative effect of teacher qualifications on students' belief in the importance of effort for academic achievement. Our findings uncover various family-wide behavioral reactions to teacher qualifications and highlight the intricacies in educational production within households.", "pred_label": "__label__POS", "pred_score_pos": 0.9398565888404846}
{"content": "ABSTRACT\nAortic dissection and rupture occur in 20–40% of patients with Marfan's syndrome. This occurs predominantly in the third and fourth decade of life, contributing to the increased morbidity and mortality of this specific group of patients. This is the first known documented case report of pre-pubertal left coronary sinus rupture with left coronary artery aneurysms with fistulous communication to both superior vena cava and right superior pulmonary vein presenting with a continuous murmur.\nThis manuscript has been assigned to a volume and issue but has not yet been published. It is either being edited, typeset or is in the proof stage of publication.\nIn the pre-published stage, this manuscript may contain statements, opinions, and information that have errors in facts, figures, or interpretation. Any final changes in this manuscript will be made at the time of publication and will be reflected in the final electronic version of the issue. The editors and authors and their respective employees are not responsible or liable for the use of any such inaccurate or misleading data, opinion or information contained in the articles in this section.", "pred_label": "__label__POS", "pred_score_pos": 0.6034993529319763}
{"content": "Jerome HughesPress TV, Brussels As they rubber-stamped the bloc's 46-page negotiating document, general affairs ministers from the 27-nation EU used words such as complicated, difficult, and tough with respect to the forthcoming talks aimed at trying to reach a free trade deal with the UK.\nMichel Barnier was referring to a claim made on a number of occasions by London-appointed Northern Ireland Secretary Brandon Lewis that there would not be a border on the Irish sea.\nHowever, this is a key component of the Brexit withdrawal agreement that the British Government has fully endorsed. It is crucial to preventing highly contentious border checks on land between the Republic of Ireland and Northern Ireland.\nWhen trade talks start next week, major challenges are also likely to emerge relating to fishing rights, employment standards, climate change, and a whole range of other issues.\nOutside the venue of the ministers' meeting in Brussels, workers' unions held a demonstration. They highlighted the fact that poverty and youth unemployment levels remain very high in the EU. It is time, they said, for the remaining 27 countries to take action.\nRight now, everything remains the same. It is as though the UK is still in the EU. But when the Brexit transition period ends on December 31, there will be wide-ranging consequences if a trade deal has not been reached. That is the outcome many experts are predicting. It's anticipated Boris Johnson is set to prioritize UK-US relations above ties between London and Brussels.\nThe UK delegation led by negotiator David Frost is due to arrive here next Monday to begin formal talks with the EU's team, headed up by Michel Barnier. According to analysts, the two biggest obstacles standing in the way of a possible deal are the unrealistic time frame and the influence of eurosceptic Donald Trump.", "pred_label": "__label__POS", "pred_score_pos": 0.6404771208763123}
{"content": "Ethical Conduct Information Ethical Code of Conduct for Humanist Professionals\nCelebrants, chaplains, invocators, and lay leaders are ambassadors of humanism and expected to uphold the highest standards of personal ethics and conduct, especially in their official duties.\nViolation of the Ethical Code of Conduct is grounds for immediate removal of endorsement. Represent Authentic Humanism\nHumanist Professionals shall uphold and represent the ethical and philosophical principles of humanism as expressed in Humanist Manifesto III: Humanist and Its Aspirations, as well as adhere to and uphold the purposes, policies, and bylaws of the American Humanist Association and the Humanist Society.\nHumanist Professionals may choose or not choose wording referencing divine/supernatural or otherwise non-humanist content in ceremonies. However, this should only be to recognize the culture, traditions, or guests of the ceremony. It is unethical to present scripture readings, explicitly supernatural elements, or elements of other religions as humanist prayer.\nHumanist Professionals should be honest in any interaction with the nature of humanism including scientific naturalism and human-based rational ethics. This is particularly important for ceremonies or coaching.\nMaintain Humanist Values\nHumanist Professionals should at all times conduct themselves in a manner that reflects the highest degree of honesty and integrity when dealing with clients. All shall be expected to treat others with courtesy, dignity, respect, and tolerance, and without prejudice or bigotry. All will treat those suffering from stress, trauma, or tragedy with the utmost empathy and care.\nPeople and the diversity they represent should be valued. this includes a diversity of belief. While Professionals need not hide their own beliefs or avoid disagreements, they should reserve arguments for the proper time and place.\nMaintain Professional Integrity\nHumanist Professionals should treat any information divulged by clients with strict confidence at all times within the extent authorized by law.\nHumanist Professionals should not use their positions of respect to further any other paid or voluntary work. They should do business primarily as ambassadors of humanism. Financial compensation is appropriate for services provided, but profit-making should never override humanist values.\nFor official work, Humanist Professionals should maintain a high standard of dress and reserve informal for times when such is called. “Vestments,” if used, should be reserved and strictly humanist in nature.\nHumanist Professionals shall protect the integrity of their profession by investigating and reporting violations that may occur.\nHumanist Professionals should never exceed their qualifications. This applies to the type and size of ceremonies, events, or counseling. It is particularly important for Professionals to not provide mental health services of any kind without proper qualifications. All should be willing to act on behalf of those they are working with and provide referrals to more-qualified personnel whenever necessary, including psychologists, religious personnel, or other celebrants or chaplains, as appropriate.\nProtect Those In Your Care\nHumanist Professionals should not publicize the content of any ceremony or activity that has been completed without first ensuring that sufficient changes have been made to ensure that identification of the subject is impossible or that subjects have authorized, in writing, use of their likeness or ceremonies.\nHumanist Professionals shall avoid exploiting those in their care, especially for commercial, sexual, political, or other favors.\nHarassment Policy\nWe strictly prohibit and will not tolerate harassment based on an individual’s protected status, including but not limited ot sexual or racial harassment.\nThis conduct includes but is not limited to:\nUnwanted sexually suggestive statements, questions or jokes; Repeatedly rejected sexual flirtations, advances, or propositions; Pressuring for sexual activity, including offering employment benefits in exchange for sexual favors or denying employment benefits in response to a refusal to provide sexual favors; Offensive touching or assault, obscene gestures or suggestive sounds; Use of insults, slurs or negative stereotyping; Circulating individually targeted offensive jokes, pictures, or other similar material; Intimidating acts, such as bullying or threatening based on an individual’s protected status; Falsely denying, lying about, or otherwise covering up or attempting to cover up conduct that is prohibited by this policy; or Any other conduct that shows hostility toward, disrespect for, or degradation of an individual based on an individual’s protected status. Chaplain Covenant\nHumanist Chaplains who work in institutions with vulnerable and non-humanist populations are expected to maintain an additional standard of pluralistic support and non-proselytism in their chaplain duties.\nHumanist Chaplains are expected to support institution personnel on their own terms, making every effort to respect and provide for the deeply-held beliefs and practices of non-humanists with just as much care and concern as they would humanists.\nHumanist Chaplains are prohibited from coercing and encouraging those professing non-humanist beliefs to adopt humanist beliefs.\nHumanist Chaplains will not invite others to humanist activities, materials, or discussion unless the chaplain has good reason to believe that the individual wishes to investigate humanism. “Good reason” might be a specific request, a specific profession of nontheistic beliefs or humanistic beliefs.", "pred_label": "__label__POS", "pred_score_pos": 0.5227909684181213}
{"content": "Shark bycatch in the experimental tuna longline fishery in Lakshadweep Sea, India Published online on 23. January 2015 Shark bycatch in the experimental tuna longline fishery in Lakshadweep Sea, India K.V. Aneesh Kumar, P. Pravin, B. Meenakumari, P. S. Khanolkar, M. V. Baiju\nABSTRACT:\nStudied were the bycatch from the experimental longline fishing operations in the Lakshadweep Sea. The experiments were conducted on converted Pablo boats, originally used for pole and line fishing operations, to capture skipjack tuna in the Lakshadweep Islands. The overall bycatch rate was very high, with a mean hooking rate of 8.05/1000 hooks compared to the targeted tuna catch (1.75/1000 hooks). Bycatch contributed 82.4% of the catch in comparison to the tuna (17.6%) Thunnus albacares, in the longline operations. Silky shark (Carcharhinus falciformes) with 89.9% was the dominant shark species followed by C. amblyrhynchos, Galeocerdo cuvier, Alopias pelagicus, Negapriion acutedens and Sphyrna lewinii with 4.7, 2.7, 1.4, 0.7 and 0.7%, respectively. Sharks contributed to 74.1% of the catch, followed by 15.7% sailfishes and 10.2% miscellaneous fishes. Higher bycatch rates were evident during evening hours compared to mornings, but the results were not significant statistically. Studies on the effects of depth on the overall fishing performance and species selectivity failed to establish any significant relationship at a depth range of 35–100 m. Soaking time had a significant effect on bycatch rates. The hooking rate of sharks declined with an increase in soaking time. Considering the high shark bycatch in the fishery, an accurate monitoring of the longline fish catches in the Lakshadweep waters is an important step towards ensuring the sustainability of other populations, especially sharks.\nJournal of Applied Ichthyology. doi: 10.1111/jai.12682", "pred_label": "__label__POS", "pred_score_pos": 0.8422092199325562}
{"content": "The United States has finally joined the bandwagon of countries testing a central bank digital currency (CBDC), Thursday reports revealed.\nGovernor Lael Brainard said during a virtual technology event yesterday that the US Federal Reserve, in collaboration with research teams from Boston Fed and Massachusetts Institute of Technology (MIT), is conducting experiments with a hypothetical digital currency.\nAccording to Brainard, both institutions have been researching blockchain technology for several years to see how the central bank can utilize it for a digital dollar alongside the effect it might have on the existing financial system.\n“We are taking the time and effort to understand the significant implications of digital currencies and central-bank-digital-currencies around the globe,” she said, adding that the dollar’s significance as a global reserve currency means the Fed has a vital role to play in the research and development of digital currencies.\nNo Issuance Yet\nAlthough the Fed is taking the next step to build and test a DLT-based currency, Governor Brainard noted that the central bank “hasn’t yet committed” to issuing a CBDC should the experiment become successful. It is strictly for research purposes, she said.\nA formal policy process would be required before the central bank can issue or use the currency. And that decision would involve the government and other stakeholders with many legal questions to be answered. Brainard noted that the Fed had not started the process, nor has it decided to start it.\nFindings from the experiment would be published, and the codebase would be made available through an open-source software for anyone to use as an experiment, the governor added.\nLeading the project, James Cunha, the senior vice president at the Boston Fed, explained that the first step is to develop an “engine and the software that can meet the needs” of CBDC for a country as big as the United States.\nAccording to Cunha, some of the significant challenges involved in the project include large transaction volumes, security, and privacy.\nChina Leading The Race\nMajor companies across different industries are already testing China’s new digital yuan in large scales.\nCryptoPotato reported in late July that Tencent-backed food delivery giant Meituan Dianping would test the country’s national digital currency on its web-based platform used for shopping foods, consumer products, and retail services.", "pred_label": "__label__POS", "pred_score_pos": 0.6047635078430176}
{"content": "Abstract\nThe role of the immune system in cancer progression has become increasingly evident over the past decade. Chronic inflammation in the promotion of tumorigenesis is well established, and cancer-associated tolerance/immune evasion has long been appreciated. Recent developments of immunotherapies targeting cancer-associated inflammation and immune tolerance, such as cancer vaccines, cell therapies, neutralizing antibodies, and immune checkpoint inhibitors, have shown promising clinical results. However, despite significant therapeutic advances, most patients diagnosed with metastatic cancer still succumb to their malignancy. Treatments are often toxic, and the financial burden of novel therapies is significant. Thus, new methods for utilizing similar biological systems to compare complex biological processes can give us new hypotheses for combating cancer. One such approach is comparing trophoblastic growth and regulation to tumor invasion and immune escape. Novel concepts regarding immune activation in pregnancy, especially reactivation of the immune system at labor through toll like receptor engagement by fetal derived DNA, may be applicable to cancer immunotherapy. This review summarizes mechanisms of inflammation in cancer, current immunotherapies used in the clinic, and suggestions for looking beyond oncology for novel methods to reverse cancer-associated tolerance and immunologic exhaustion utilizing mechanisms encountered in normal human pregnancy.\nKeywords Cell-free fetal DNA Circulating tumor DNA Immunotherapy Inflammation Toll like receptors ASJC Scopus subject areas Immunology and Allergy Immunology", "pred_label": "__label__POS", "pred_score_pos": 0.6500962972640991}
{"content": "For this lightning talk, I wish to provoke thought by questioning assumptions around OER as it is understood by the mainstream. Just as philosophers have long wished us to better understand our relationship to technology, we should now more thoughtfully approach \"open\" with all its promises including its dangers and risks. This talk will seek to build understanding around the trajectories that are preferable or probable for the OER movement, but also demand consideration for unexpected, radical shifts in law, technology, and society. This video will be edited and include reuse of CC licensed and public domain images and video, creating a collage around the topic of OER and the future.\nLearning Outcomes: Viewers will be shown lenses through which alternative futures of OER might be imagined, offering questions and provocations to foster useful discussions.", "pred_label": "__label__POS", "pred_score_pos": 0.9161967039108276}
{"content": "Abstract\nThe vertebrate complement system consists of sequentially interacting proteins that provide for a rapid and powerful host defense. Nearly 60 proteins comprise three activation pathways (classical, alternative, and lectin) and a terminal cytolytic pathway common to all. Attesting to its potency, nearly half of the system's components are engaged in its regulation. An emerging theme over the past decade is that variations in these inhibitors predispose to two scourges of modern humans. One, occurring most often in childhood, is a rare but deadly thrombomicroangiopathy called atypical hemolytic uremic syndrome. The other, age-related macular degeneration, is the most common form of blindness in the elderly. Their seemingly unrelated clinical presentations and pathologies share the common theme of overactivity of the complement system's alternative pathway. This review summarizes insights gained from contemporary genetics for understanding how dysregulation of this powerful innate immune system leads to these human diseases.\nOriginal language English Pages (from-to) 25-52 Number of pages 28 Journal Annual Review of Pathology: Mechanisms of Disease Volume 12 DOIs State Published - Jan 24 2017 Keywords Age-related macular degeneration Alternative complement pathway Atypical hemolytic uremic syndrome C3 C3 glomerulopathies CD46 Factor B Factor H Factor I", "pred_label": "__label__POS", "pred_score_pos": 0.5973248481750488}
{"content": "Qumin is proud to announce that we have been appointed by leading Pharma company Sanofi.\nUnder the guidance of our Insight and Strategy team, we will be providing market deep-dive research on category dynamics and latent semantic and semiotic analysis on leading category products.\nAn ageing population, overall income growth and a deeper involvement of social capital have resulted in a significant transformation of China’s Health and Pharma sector over the past decade.\nChina has already become the second-largest pharmaceutical market and the largest healthcare market in the world, maintaining high growth momentum.\nAlthough COVID-19 has brought challenges to the Chinese and global economy since early 2020, it also sped up the digital transformation of the healthcare industry.\nQumin’s team are excited to be supporting businesses like Sanofi to understand consumer and brand behaviour on these digital channels.", "pred_label": "__label__POS", "pred_score_pos": 0.8840229511260986}
{"content": "Children in Haiti face numerous challenges, particularly in the current context of political unrest. Thousands of Haitian children fall victim to trafficking, prostitution, and HIV/AIDS, and many thousands more have no access to basic education. Children are also used in armed gangs that have been terrorizing Port-au-Prince in recent months.\nIn a bid to ensure children are not forgotten in Haitian politics, the workshops aim to use the unique role of political leaders as public figures and community motivators to promote children's rights and the condemnation of their involvement in gangs. It is expected that leaders participating in the workshops will inscribe these principles in their party platforms.\n\"This training is one part of IOM's broad strategy to promote positive alternatives to gang violence, particularly for the youth,\" says IOM Haiti chief of mission, Maureen Achieng. \"We hope that by raising the awareness of political leaders to the issue, they can help spread the message to their constituents and we can keep children out of armed gangs.\"\nThe training is being conducted by the Child Protection Unit of the UN Mission for Stabilization in Haiti (MINUSTAH) and UNICEF with cooperation from the Haiti Institute for Social and Political Training. The seminars include members of major political parties and take place over several days in August in the Haitian capital, Port-au-Prince.\nIOM is co-sponsoring the workshops as part of its Haiti Transition Initiative programme, funded by USAID's Office of Transition Initiatives. The programme, which began in May 2004, aims to stabilise communities by bridging the gap between the government and the general population by creating dialogue between them and by rehabilitating community infrastructures. A key component of this programme is to provide alternatives to gang violence through employment and community activities.\nFor further information, please contact:\nStephanie Broughton\nIOM Port-au-Prince Tel +509 245 51 53 Email: sbroughton@iom.int International Organization for Migration Copyright © IOM. All rights reserved.", "pred_label": "__label__POS", "pred_score_pos": 0.6905921697616577}
{"content": "Abstract\nObjectives: To investigate the structural validity of a battery of physical performance tasks and to investigate the construct validity of the resulting factors. Design: A measurement study. Setting: A large, private orthopedic clinic and a physical therapy clinic in an urban area. Participants: One hundred three consecutive adult patients with low back pain who were referred for physical therapy assessment. Interventions: Not applicable. Main Outcome Measures: The physical performance battery was composed of the 50-foot speed walk, 5-minute walk, repeated trunk flexion, sit to stand, loaded reach, rollover tasks, and Sorensen upper-body lift. Participants also completed 5 self-report measures. Results: Two correlated (.74) factors, speed and coordination and endurance and strength, were derived from the physical performance tasks. The Sorenson upper-body lift task was the only indicator that was not useful in defining the factors. Both factors had statistically significant correlations with measures of physical disability, lack of self-efficacy, and negative affect. Both factors had a trivial correlation with a numeric rating of pain intensity. Conclusions: There is support for 2 meaningful empiric groupings (ie, the derived factors) of the performance tasks. Pain intensity had a trivial overlap with speed-coordination and endurance-strength factors.\nKeywords Low back pain Physical endurance Rehabilitation ASJC Scopus subject areas Physical Therapy, Sports Therapy and Rehabilitation Rehabilitation", "pred_label": "__label__POS", "pred_score_pos": 0.8683652281761169}
{"content": "Israeli (Hebrew:ישראלי, lit. Israeli) was an Israeli daily Hebrew language newspaper distributed for free in railway stations, bus terminals, and Delek gas stations. Based on the concept of the Metrofree daily newspapers, it was geared toward a young, urban, and mobile clientele.\nThe newspaper, first published in January 2006, was co-owned by Sheldon Adelson and Hirsch Media (owned by Shlomo Ben Tzvi) and published by Israeli News Ltd. Its headquarters were located on Menahem Begin Road in Tel Aviv. Its original budget was planned to be US $35 million over three to four years.\nIt was long suspected that the paper was losing money, but as the number of pages increased from the originally-planned sixteen to twenty-four, and often even more (up to 40), the publishers insisted that the newspaper's expanding size was a sign of strong demand from advertisers. Israeli aimed to become the second-largest paper in Israel, behind Yediot Aharonot, and claimed to print 200,000 issues each day in two daily editions, morning and evening. Criticism of this claim led the publishers to consider numbering each copy under supervision of an accounting firm.\nLiquefied natural gas (LNG) is natural gas (predominantly methane, CH4) that has been converted to liquid form for ease of storage or transport. It takes up about 1/600th the volume of natural gas in the gaseous state. It is odorless, colorless, non-toxic and non-corrosive. Hazards include flammability after vaporization into a gaseous state, freezing and asphyxia. The liquefaction process involves removal of certain components, such as dust, acid gases, helium, water, and heavy hydrocarbons, which could cause difficulty downstream. The natural gas is then condensed into a liquid at close to atmospheric pressure by cooling it to approximately −162°C (−260°F); maximum transport pressure is set at around 25kPa (4psi).\nLNG achieves a higher reduction in volume than compressed natural gas (CNG) so that the (volumetric) energy density of LNG is 2.4times greater than that of CNG or 60 percent that of diesel fuel. This makes LNG cost efficient to transport over long distances where pipelines do not exist. Specially designed cryogenic sea vessels (LNG carriers) or cryogenic road tankers are used for its transport. LNG is principally used for transporting natural gas to markets, where it is regasified and distributed as pipeline natural gas. It can be used in natural gas vehicles, although it is more common to design vehicles to use compressed natural gas. Its relatively high cost of production and the need to store it in expensive cryogenic tanks have hindered widespread commercial use. Despite these drawbacks, on energy basis LNG production is expected to hit 10% of the global crude production by 2020.(see LNG Trade)", "pred_label": "__label__POS", "pred_score_pos": 0.8677565455436707}
{"content": "The current state of cybersecurity is a global issue that requires an equal amount of due diligence regardless of the industry your organization is part of. To make for a consistent approach when applying best security practices across the enterprise environment, the NIST (National Institute of Standards and Technology), has posted the five pillars for building a robust cybersecurity framework.\nEach of these five pillars, or functions, provides the foundation for building a successful and holistic cybersecurity program in your enterprise.\nIdentify\nThe identify function is used to help organizations develop and understand their cybersecurity risk when evaluation their business systems and networks. This initial step builds a foundation for deploying effective policies on how to protect both physical and digital business assets adequately.\nProtect\nThe protect function is the action stage of cybersecurity planning and supports the organization's ability to limit or contain the impact of cybersecurity events. This involves protecting assets through the use of IAM (Identity and Access Management) solutions, database security technologies, staff training, and other safeguards that ensure the delivery of critical infrastructure services.\nDetect\nThe detect function ensures the timely discovery of cybersecurity incidents so they can be responded to. This includes recognizing anomalies or events in system and networks as they happen and verifying the effectiveness of protective measures used to respond to these activities.\nRespond\nThe response function is a critical pillar and refers to all appropriate activities needed when taking action against detected cybersecurity incidents. This is an essential component when containing potentially devastating attacks as they are discovered. This includes managing communications during and after events with appropriate incident response teams, stakeholders, and law enforcement while driving the analysis, mitigation activities, and technologies necessary to resolve the issues.\nRecover\nThe recover function outlines all activities necessary to restore any capabilities or services in the event of a catastrophic event or large-scale business disruption. This includes implementing recovery planning processes, training procedures, and teams that will drive recovery efforts and implement improvements based on lessons learned from new events and recovery initiatives.", "pred_label": "__label__POS", "pred_score_pos": 0.8572304844856262}
{"content": "Draft of Australia’s Strategy for Nature 2018 - 2030\nThis submission has been prepared by the Australian Environmental and Planning Law Committee of the Law Council’s Legal Practice Section.\nThe Committee welcomes the opportunity to respond to the National Biodiversity Strategy Secretariat in relation to\nAustralia’s strategy for nature 2018-2030: Australia’s biodiversity conversation strategy and action inventory published by the Department of the Environment and Energy.\nThe 2016 Commonwealth State of the Environment report concluded that “Australia’s biodiversity is under increased threat and has, overall, continued to decline.”\nThe Law Council is concerned that the current range of laws and policies designed to address biodiversity loss, conservation and protection have not been adequate to prevent significant detrimental impacts on Australia’s biodiversity. It supports initiatives to make improvements in that area.\nThe Committee has reviewed the Draft Strategy. It has also had the benefit of considering a comprehensive submission in response to the Draft Strategy prepared by the National Environmental Law Association (NELA).\nThe Committee supports the vision stated in the Draft Strategy that:\nAustralia’s nature, now and into the future, is healthy and resilient to threats, and valued both in its own right and for its essential contribution to our health, wellbeing, prosperity and quality of life. You can read the full submission below.", "pred_label": "__label__POS", "pred_score_pos": 0.6390877962112427}
{"content": "By Shawn C at August 15 2020 06:15:13\nNo matter the economic slump, increasing profits is typically the number one goal of any business. To ensure profitability, a company must demonstrate a competitive advantage over others in its industry, either by cost leadership (same product as competitors, lower price), differentiation (same price, better services), or focusing on an exclusive segment of the market (niche). For long term maintenance of competitive advantage, a firm must ensure that its methods cannot be duplicated or imitated. This requires constant analysis and regular reinvention of competitive strategies.\nWhen you sit down to compile all of the elements of your business plan, make sure you have each section able to stand on its own merits. This means you should not reference other sections sending the reader (your potential investor) back and forth between sections.", "pred_label": "__label__POS", "pred_score_pos": 0.7234538793563843}
{"content": "High-impact practices (HIPs) are educationally effective teaching and learning practices that, when designed well and implemented with fidelity, have been shown to accrue educational benefits for students. HIPs share a set of underlying characteristics that help make them effective, including “considerable time and effort,” real-world application of learning, meaningful engagement across differences, and “frequent and substantive feedback” (NSSE, nd).\nIn fall 2017, the Kirwan Center assembled a leadership team representing four USM institutions to help inform the Kirwan Center’s efforts to scale, sustain, and assess High-Impact Practices (HIPs) system-wide. The team is focusing on building capacity within their institutions to track student participation in HIPs, adapt and use emerging quality frameworks associated with HIPs, and assess the individual and cumulative impact of HIPs on student retention/progression/completion and on student learning. In undertaking this work, the Kirwan Center hopes to catalyze a set of lead institutions in advancing their own HIPs efforts while also positioning them to serve as models for other institutions within the System and across the country in scaling, sustaining, and assessing high-quality HIPs.", "pred_label": "__label__POS", "pred_score_pos": 0.8480388522148132}
{"content": "What is so smart about a smart meter?\nSmart meters are considered smart mainly because homeowners can track their energy usage, while their readings are automatically sent to their suppliers. This later provides customers with a more precise energy bill.\nSmart meters vs standard meters\nThere are several differences between the standard meter and the smart meter. The Office of Gas and Electricity Markets (Ofgem) website provides more information on smart meters. Standard meters require the customer to report their readings. On the other hand, smart meters send the usage information through a “mobile network” to the customer’s supplier. In addition, smart meters include an in-home display that allows homeowners to keep track of their energy consumption and calculate their total costs. Unlike standard meters, bills from a smart meters turn out to be more accurate because costs are not based on “up-to-date data” estimates.\nImage Credit How does a smart meter function? Smart meters are made up of three main parts, which include the smart electricity meter, the smart gas meter, and the in-home display, which still require a gas meter box and an electric meter box. These separate sections communicate with each other wirelessly and then the information is transferred through a central hub that is linked to a Data Communications Company (DCC) network. Energy suppliers also receives automatic updates from your smart meter detailing the exact amount of gas and electricity that a customer has used. Several energy suppliers also offer apps to customers with smart meters, which allows users to see their updated gas and electricity consumption. Moving to smart meters\nSmart meters will most likely gain popularity. It has been estimated that the smart gas meter market will increase to USD 10.92 billion by 2026. As a result, the need for both a gas meter box and an electric meter box remains. If you need to replace your gas meter box or electric box, you can go to the MeterBox website to view the boxes that are available.\nSmart meter concerns\nThe government’s big campaign aimed to switch about 53 million standard meters with smart meters by 2020 continues. However, concerns about smart meters still linger. As a result, the government has decided to no longer make it mandatory, but has encouraged energy suppliers to offer them to their customers as standard.", "pred_label": "__label__POS", "pred_score_pos": 0.5628817081451416}
{"content": "\"I take...an outward route, arguing that the Agrarian project was and must be seen as a willed campaign on the part of one elite to establish and control 'the South' in a period of intense cultural maneuvering. The principal organizers of I'll Take My Stand knew full well there were other 'Souths' than the one they touted; they deliberately presented a fabricated South as the one and only real thing.\"\nIn Inventing Southern Literature Michael Kreyling casts a penetrating ray upon the traditional canon of southern literature and questions the modes by which it was created. He finds that it was, indeed, an invention rather than a creation. In the 1930s the foundations were laid by the Fugitive-Agrarian group, a band of poet-critics that wished not only to design but also to control the southern cultural entity in a conservative political context. From their heyday to the present, Kreyling investigates the historical conditions under which literary and cultural critics have invented \"the South\" and how they have chosen its representations. Through his study of these choices, Kreyling argues that interested groups have shaped meanings that preserve \"a South\" as \"the South.\"\nAs the Fugitive-Agrarians molded the region according to their definition in I'll Take My Stand, they professed to have developed a critical method that disavowed any cultural or political intent or content, a claim that Kreyling disproves. He shows that their torch was taken by Richard Weaver on the Right and Louis D. Rubin, Jr., on the Center-Left and that both critics tried to preserve the Fugitive-Agrarian credo despite the severe stresses imposed during the era of desegregation.\nAs the southern literary paradigm has been attacked and defended, certain issues have remained in the forefront. Kreyling takes on three:\nreconciling the imperatives of race with the traditional definitions of the South;testing the ways white women writers of the South have negotiated space within or outside the paradigm; andanalyzing the critics' use and abuse of William Faulkner (the major figure of southern literature) as they have relied on his achievement to anchor the total project called Southern Literature.\nMichael Kreyling, a professor of English at Vanderbilt University, is the author of several books, includingEudora Welty's Achievement of OrderandAuthor and Agent: Eudora Welty and Diarmuid Russell.\neISBN: 978-1-60473-776-9\nSubjects: Language & Literature\nTable of Contents\nYou are viewing the table of contents\nYou do not have access to thisbookon JSTOR. Try logging in through your institution for access.", "pred_label": "__label__POS", "pred_score_pos": 0.5037111043930054}
{"content": "The recent conflict inCôted'Ivoire has led to the militarization of many young civilians on both belligerent sides, especially in the west of the country. What is of particular interest is that many of these youths have assumed a function of 'commuting' conscripts, alternating periods of semi-military work, where they had to report to some kind of warlike hierarchy, with periods at home where they went back to a quasi daily routine. This became particularly characteristic as the Ivoirian war evolved into a situation of 'no peace, no war' with sporadic violence still occurring, but only at certain periods and within specific settings. This book examines the different processes that led to the militarization and demilitarization of youth inCôted'Ivoire during the period 2002-2007 in a context where borders between the military, civilian, and humanitarian arenas have never been strict, and have varied according to conflict phases, individuals' social networks and the locality of the recruitment. [Book abstract]Free online at http://hdl.handle.net/1887/17912\nYear of publication: 2011Series: African Studies CollectionVolume: 36\nThe following extensions are supported: png, jpeg, jpg, gif, txt, csv, swf, pdf, doc, docx, rtf, xls, xlsx, ppt, pptx, odt, ods, eps.", "pred_label": "__label__POS", "pred_score_pos": 0.654771625995636}
{"content": "Married parents are proud of their children, want them to succeed, and rarely feel any jealousy of them. Moreover, children in happy married families rarely feel jealous of their parents. However, divorcing parents often feel jealous if their children form a close bond with one parent and the children often feel jealousy when a divorced parent begins dating. Jealousy within a divorcing family is caused by insecurity, dependency, and fear of abandonment. Divorcing mothers most often feel jealous of their daughters while divorcing fathers most often feel jealous of their sons. Daughters most often feel jealous when their father starts dating while sons most often feel jealous of their mother when she begins dating.\nCauses of Parental Jealousy\nA divorcing parent often feels jealous when their children establish a close relationship with the other parent. The parent may criticize their children because of his or her jealous feelings, and the negative messages have a damaging effect on the children’s emotional development, making the children feel they are “not good enough” to deserve love.\nDistorted Relationship with Parents\nA divorcing parent who feels jealousy can give his or her children confusing emotional messages. Children need to feel loved by both their parents, but if they get too close to their divorcing father, their mother may feel threatened and the divorcing father may feel jealous if the children get too close to their mother. But, if the children stay away from one parent, they lose that parent’s love and support. These children are caught in an emotional bind. To avoid this damaging situation, divorcing parents should strive to maintain a close relationship with their children, support them, and offer the children love and encouragement.\nAvoid Feeling Jealous During a Divorce.\nThere are two main ways for divorcing parents to avoid feeling jealous of their children during divorce. The better method is to opt for collaborative divorce rather than litigation. By choosing collaborative divorce, the parents will learn how to communicate, develop better parenting skills, minimize the stresses of divorce, avoid feeling insecure, and have a good chance of avoiding jealousy. If the parents choose litigation and one of them later feel jealousy toward their children, the jealous parent should see a counselor about their jealousy.\nJealousy and Control\nWhen a divorcing parent feels jealous and insecure, he or she often attempts to control the other spouse’s relationship with their children. However, the more a divorcing spouse tries to control how the other parent deals with their children, the more resentful the other parent will become. The divorced parents’ relationship deteriorates and creates more insecurity, forming a negative cycle that just makes the jealousy worse. The solution is for the jealous parent to stop trying to control the other parent and allow him or her to discipline the children without being second guessed.\nJealous Children and Dating Parents\nAfter a divorce, children need to establish a new relationship with their divorced parents. Daughters need to reconnect with their divorced father and sons need to love and protect their divorced mother. Parent-child relationships get especially complicated when the divorced parents begin dating or get re-married. Boys typically become protective of their mother, resent their father abandoning them, and feel angry and jealous of mother’s new boyfriend. After a divorce, parents are usually not dating and have free time to spend with their children.\nDuring this post-divorce transition, children become reattached to their divorced parents. However, when a divorced parent begins dating, the new relationship can cause jealousy among the children. The daughter may feel displaced by her father’s new girlfriend and the son may feel displaced by Mom’s new boyfriend. Additionally, Mom may worry about what would happen if the children decided they wanted to live with their Dad and his new spouse, and that may cause her to feel jealous of his bond with the children.\nMost children of divorced parents experience jealousy when their parents begin dating and divorced parents may feel jealous of their children’s bond with the ex-spouse. Jealousy is a natural reaction when family dynamics shift. And, the dating parent is usually so happy to be in a new relationship that he or she may neglect the children for a while. The best way to handle family jealousy is to hold a frank and open discussion between parent and children about their feelings. Also, the children should make an effort to get to know father’s girlfriend or mother’s boyfriend—they may actually find they like them.", "pred_label": "__label__POS", "pred_score_pos": 0.8224612474441528}
{"content": "• Many asthma patients across the EU5 (France, Germany, Italy, Spain, the United Kingdom) require lifelong treatment to manage their condition. This places a substantial financial burden on the national healthcare systems, and the launch of novel, premium-priced biologic therapies targeted at severe refractory asthma will undoubtedly exert additional pressure.\n• The behavior of payers—as they strive to control disease-associated costs—will play an increasingly influential role in shaping the market access landscape for asthma in the EU5, such that emerging biologics must compete to prove their worth. • Against a backdrop of budget constraints and increasing competition, this research explored the evolving reimbursement and prescribing environment for asthma biologics seeking to secure optimal market access. Authors: Elena Kozhemyakina, Ph.D.; Andrea Kravit ; Janie Cox, Ph.D.", "pred_label": "__label__POS", "pred_score_pos": 0.8345448970794678}
{"content": "Abstract\nThe use of molecular and continuum emission spectra from multiple bubble (MB) and single bubble (SB) sonoluminescence (SL) is explored as a probe of bubble temperature during cavitational collapse. It is proposed that molecular and continuum SL arise from different chemical pathways, which occur during discrete intervals along the cavitational collapse time line, thus yielding different cavitation temperatures. A coupled bubble dynamics/chemical kinetic model of cavitational collapse is developed and used to explore a variety of proposed molecular SL mechanisms for the C\n2(d→a), CN(B→X), and OH(A→X) emissions. Molecular SL is shown to arise from chemiluminescent reactions of seed molecules (e.g., hydrocarbons, N 2, H 2O) and their dissociation products, and occurs during the early and middle stages of cavitational collapse. This emission is broadly characterized as originating from reactions involving singly or multiply bonded molecular precursors with corresponding effective emission temperature ranges of approximately 3000-8000 and 8000-25 000 K, respectively. An analysis of an experimentally observed CN(B→X) MBSL spectrum is reported which is consistent with CN emission occurring over a broad distribution of cavitation temperatures ranging from approximately 5000 to 15 000 K. Continuum SL is attributed to transitions of electrons produced by high-temperature ionization and confined to voids in the dense fluid formed during the latter stages of cavitational collapse. The continuum is similar for both SBSL and MBSL, and is characterized by a temperature range of ≈20 000-100 000 K. The observation of significant molecular emission for MBSL, and not for SBSL, is attributed to the broad distribution of initial bubble sizes for MBSL. In SBSL, a single bubble is repetitively cycled through collapse and reexpansion, and its collapse is driven well into the continuum emission regime. In MBSL, only a small fraction of the bubbles will be driven to this level of collapse, while a much larger fraction will attain only the single or multiple bond chemistry regimes. Thus in MBSL the bubble size distribution averaged emission will tend to enhance the molecular relative to the continuum emission. It is concluded that both SBSL and MBSL are consistent with an adiabatic compressional heating description of bubble collapse. ASJC Scopus subject areas Engineering(all) Physical and Theoretical Chemistry", "pred_label": "__label__POS", "pred_score_pos": 0.578167736530304}
{"content": "Pain is a common condition, characterised by a highly unpleasant sensory and emotional experience.Read more\nSport is at the centre of many people’s lives. Yet changed circumstances due to the current health crisis are leaving sportspeople and athletes with a gaping hole where their passion once was, unable to perform for pleasure, or their livelihood, in the same way. At Bio Concepts, our General Manager of Marketing and Sales, Jane Hermann, also doubles as an Ironman Triathlete competing on a global scale. She shares her experience as an athlete adjusting to this tricky time, giving insight into the impact this has had on her training.Read more\nCurrently, access to medical services and testing is reserved for those who are unwell, but what if you have questions about how you can best support your own and your family’s health at this time? What if you have other health concerns or you're anxious and stressed?Read more\nPermission to let go of the pressure to be productive during this pandemic. We’re in the murky midst of a global health crisis, grappling to navigate an uncertain situation and chaotic changes to our world that most of us have never experienced before. Yet, adding to the cocktail of emotions this situation has served up, many of us may be feeling the weight of another pervasive pressure – productivity.Read more\nBringing a baby into the world is a life changing experience. But when life as we know it has already changed so significantly around us, we explore what impact this pandemic is having on new mothers, faced with raising a newborn in a reality far from the one they would have hoped for. As this undefined period of isolation places restrictions on visitations and support networks, we hear from a new mum who shares her raw and honest experience during this challenging and emotional time.Read more", "pred_label": "__label__POS", "pred_score_pos": 0.512776255607605}
{"content": "It's snowing and cold today where I live. These conditions create a stubborn glaze of ice on the cars parked outside. The sounds of frantic scrapping on the windshields ricochet through the neighborhood.\nIn our haste to get on our way, we tend to clear a peephole through the ice just large enough to see ahead. Yet, such a strategy is dangerous. It limits our field of vision and diminishes our capacity for strategic response. It's a quick fix with potentially devastating results.\nToday's hyper accelerated, disconnected world can quickly ice our souls. Yet we tend to navigate through it with only a peephole of vision. As a result, we steer our way through contemporary life with a limited perspective, a diminished response, and a deflated spirit. A more expansive sight line is needed to keep our souls thawed and our lives expansive.\nHave you ever had a conversation that went far deeper than the words spoken or an experience where you felt you had participated in something sacred–that you had been part of the unbidden activity of a reality much more expansive than yourself? If so, you are experiencing life beyond the peephole.\nOne of the more significant resources I found to scrape ice from my soul and broaden my vision is the book \"God hides in plain sight: How to see the sacred in a chaotic world\" by Dean Nelson. In this colorful, story-driven introduction to sacramental living, Nelson offers human beings a way to see the presence of God amid the chaos and acceleration of every day life.\nAn expansive life beyond the peephole. That's the way to go!", "pred_label": "__label__POS", "pred_score_pos": 0.8270105123519897}
{"content": "At RCR Law, we believe that practical legal advice should be accessible to everyone. Unfortunately, that’s not always the case. Our thriving pro bono practise was established in response to a need and represents our commitment as a firm to invest in the community we call home. Every lawyer commits a minimum of 35 hours to pro bono work every year, a truly rewarding experience that offers personal and professional enrichment.\nWe’re delighted to be a signatory to the national pro bono target with the Australian Pro Bono Centre.\nMeet the pro bono team Nominate someone deserving of our pro bono program.\nWe have a genuine desire to ensure everyone has access to the legal support they need, when they need it, regardless of their circumstance. If you know someone in need of professional support from a team committed to delivering practical and understandable legal support, please reach out via the form below.\nPartnering with positive change-makers within the community.\nWe’re proud to be sponsors of the TIACS Foundation – an organisation dedicated to empowering people with mental health tools and resources. By removing physical and financial barriers to valuable, professional support, the foundation aims to reduce the rate of suicide and self-harm within Australia.\nThere is a well-researched link between financial burden and mental health issues. As part of our partnership, the RCR legal team frequently provide onsite support, integrating into the TIACS team in order to provide free legal and financial advice to individuals.", "pred_label": "__label__POS", "pred_score_pos": 0.8330958485603333}
{"content": "KPMG’s 2021 personal tax planning guide provides valuable information about the current tax laws and provides planning tips.\nTo support year-end tax planning and help you plan for the year ahead, KPMG LLP (KPMG) presents the\n. Prepared by tax professionals from our Washington National Tax office, the guide provides valuable information and insights to support your year-end tax planning and ensure your tax position is in shape heading into 2021. 2021 Personal Tax Planning Guide\nWhat's new for 2021\nThe Coronavirus Aid, Relief, and Economic Security Act\nAmong the key temporary changes in the CARES Act affecting individuals are:\nA retroactive suspension of the excess business loss limitation for tax years beginning before 2021 (creating the potential for some business owners to access a refund of cash or to pay a reduced tax liability).\nA 5-year carryback period for NOLs arising in tax years 2018, 2019, and 2020.\nA temporary suspension of the TCJA-imposed 80% of taxable income limitation on the use of certain NOLs.\nA potential opportunity for individuals who itemize to deduct up to 100% of their adjusted gross income for certain charitable cash contributions made in 2020.", "pred_label": "__label__POS", "pred_score_pos": 0.6626662611961365}
{"content": "OR WAIT 15 SECS\nEarly signs of bilirubin-induced neurologic damage in healthy term and near-term newborns are often vague. A comprehensive approach to management helps prevent rapid progression and irreversible consequence.\nA late-night telephone call from a parent of a recently discharged newborn reporting that the baby has, or may have, jaundice heralds a potential medical emergency-especially when jaundice is coupled with concerns about poor feeding, excessive sleepiness, irritability, or lethargy. This constellation of complaints requires detailed questioning about specific signs and symptoms, a review of the birthing and postnatal history and predischarge data, and, possibly, an emergency neurologic evaluation of muscle tone, alertness, and cry pattern for evidence of bilirubin-induced neurologic dysfunction (BIND).\nAlthough the clinical signs described by the parent sound vague, and may simply reflect a new parent's anxiety or inexperience, they also could be early, nonspecific-but nevertheless sentinel-signs of acute bilirubin encephalopathy (ABE). ABE refers to the acute, and often progressive, manifestations of bilirubin toxicity that are seen in the first weeks after birth. When unmonitored or untreated, they may progress rapidly to advanced manifestations such as opisthotonus and seizures. If intervention to reduce the bilirubin load rapidly is neither timely nor efficient, chronic, permanent clinical sequelae of bilirubin toxicity-referred to as kernicterus-result and become increasingly apparent during infancy.\nNewborn jaundice generally has a reassuringly benign outcome. It is kernicterus following an acute, brief, preventable exposure to extreme hyperbilirubinemia that can have lifelong deleterious effects. This article discusses the clinical signs, symptoms, and known causes of kernicterus and presents a systems-based strategy for preventing it. The strategy is based on predischarge screening and a bilirubin measurement plotted on the hour-specific bilirubin nomogram to identify newborns at risk of severe hyperbilirubinemia and to target follow-up to prevent irreversible damage.\nThe damage ranges from minimal to severe with signs of ABE: kernicteric sequelae, isolated auditory neuropathy (a form of sensorineural hearing loss), extrapyramidal movement disorders, or a combination of neuromotor, sensorineural hearing disability, and visual disability. Some experts believe that BIND may have milder, subtler neurologic manifestations, but this theory is unproven.\n6-11", "pred_label": "__label__POS", "pred_score_pos": 0.8303247690200806}
{"content": "CBD Users May Test Positive for Marijuana on Urine Drug Screen\nMedscape recently featured a set of findings from the MIND program which were\npublished in JAMA psychiatry last week! Although it is often assumed individuals using hemp-derived products will test negative for THC, 50% of study participants enrolled in the open label phase of our clinical trial tested positive on a urine drug screen after four weeks of using the full-spectrum high CBD product. This occurred even though the product contained far less THC than is legally allowable for hemp-based products in the US, and occurred despite the fact that no individuals reported feeling high or intoxicated when using the product. Accordingly, results suggest some individuals who consistently use hemp-based products, which are legal in the US, may be at risk for adverse legal consequences.", "pred_label": "__label__POS", "pred_score_pos": 0.6857614517211914}
{"content": "You've probably seen someone put a fruit in a brown paper bag and store it in a humid place to ripen it. If storage in a dark place is supportive to the ripening process, then common sense seems to dictate that putting fruit under light would hinder ripening. Unfortunately, it's not quite that simple. While light affects ripe fruit, it does so indirectly.\nHow Ripening Works\nFruits produce ethylene gas as they mature. This gas is a ripening agent, so exposure to it supports further ripening. However, fruits also need the right temperature and humidity to ripen. Green fruits generally take 2 weeks to ripen in an environment with a temperature of between 65 and 70 degrees Fahrenheit, or 3 to 4 weeks in 55-degree conditions.\nRole of Light\nLight does not directly contribute to the ripening process and fruits actually don't need any light to ripen. However, light shining on a fruit could increase the temperature in that fruit's path. If the light results in a favorable temperature, the fruit ripens. If your fruit is already ripe, then the effect will be an overly ripe fruit.\nNegative Impact\nA big bowl of ripe fruits on a kitchen counter or table provides visual appeal and welcomes visitors to help themselves. However, if the fruit is in the path of intense light, then the heat produced by the light can cause your fruit to over-ripen quickly. As a result, you'll have to discard them. Thus, if you wish to display fruit, find an out-of-the-way spot in which sunlight or indoor lighting does not touch it.\nAlternative\nIf you've brought home fruits from the grocery store that are already ripe, the best way to keep them ready to eat for the longest possible is to store them in your refrigerator. On the other hand, some produce, including tomatoes, contain substances that degrade in cold temperatures. In such cases, storage in a cool, dark, dry place is best. If your fruit has not yet fully ripened, place the fruit in a paper bag and place the bag in a pantry or cupboard.", "pred_label": "__label__POS", "pred_score_pos": 0.5067278146743774}
{"content": "17 March 2020\nThe recent coronavirus (Covid-19) outbreak in the world and in Turkey has been affecting all aspects of our daily lives which obviously includes the severe disruption of economic and commercial life. In these extraordinary times, it is important to understand how the legal regulations approach to these circumstances with the aim to ensure sustainability of commercial activities. For this reason, it would be useful to consider the potential impacts of the outbreak on commercial contracts under Turkish laws, particularly within the framework of the Turkish Code of Obligations (\"TCO\").\nCompare to the risks existing in the ordinary course of life, circumstances of \"force majeure\" are envisaged as exceptions to the basic principle of sanctity of contracts (pacta sunt servanda), under contracts law.\nAs known, the current situation has been declared as \"pandemic\" by the World Health Organization. Within the scope of contractual relations, the coronavirus outbreak stands as an inevitable and unpredictable situation. Considering the severity of the outbreak, under contracts law; this situation may certainly be considered as an external event, a force majeure that may lead to breach of a debtor's obligations beyond its control.\nCommercial contracts often contain \"force majeure\" provisions which basically aim to address suspension of certain obligations, non-liability of the party who fails to perform its obligations and under certain conditions termination of contract, and these provisions generally include epidemics together with other specific unexpected events. The parties may agree on the list of events that will be considered as force majeure in their contracts.\nIf a contract does not adequately address the events and consequences of force majeure or in cases where a force majeure provision is not included in the contract, the general provisions of the TCO shall be applied.\nDepending on the nature of the obligations under the contract in question, an epidemic may be recognised as a circumstance leading to temporary or permanent impossibility to perform. For example; in regions where the epidemic is widespread, due to risks associated with the epidemic or as a result of governmental measures such as travel, free movement, export or import restrictions, it may truly become impossible to perform obligations related to certain goods or services. Especially in the case of an obligation with a definite due performance date (i.e. if the postponed/delayed performance of an obligation would not satisfy the expectations of the purchaser of goods or services or if late performance is not possible), the force majeure will be deemed to have made it permanently impossible to perform the obligations and therefore the debtor's obligation to perform will cease immediately and au tomatically without resorting to any judicial procedure (TCO Art. 136).\nHowever, if a postponed/delayed performance is acceptable for the other party and if this is practically possible; so that if the force majeure causes only a temporary impossibility in terms of the performance of that contract, it will be accepted that the debtor is in temporary default without fault. In this case, the debtor will not be obliged to pay any compensation due to this delay (TCO Art. 112). However, following the disappearance of the force majeure event, the debtor will be obliged to perform the due obligation in question. Existence of permanent impossibility can also be argued in cases where it is not possible to foresee when such impossibility will come to an end (for example, in continuous contractual relations) and that in good faith it is not possible to expect the debtor to be bound by the contract for an unforeseeable period of time.\nOn the other hand, it should be noted that an epidemic may not always result in impossibility of performance in relation to certain goods and services (i.e. services of online advertising, broadcasting and some other goods and services). In such cases, if performance of the obligations would still be exceptionally costly and burdensome, due to unexpected developments or as a result of changes in the financial market conditions, the adversely affected party may request adaptation of the contract from the court due to hardship in performance and if not possible, may withdraw from the contract (TCO Art. 138) (provided that the obligations in question have not been fulfilled yet or fulfilled with reserving the rights arising out of such events).\nIf you have any questions regarding our above note, please do not hesitate to contact us.", "pred_label": "__label__POS", "pred_score_pos": 0.6381858587265015}
{"content": "For nearly two years, we have held theme-based Healing Circles for Virginia Mason Hospital in Seattle. Our themes include self-care, grief and loss, relationship and communication, growing with and navigating emotions, reframing thoughts, mindfulness, joy, purpose, and connection. These themes generate a meaningful and integrated experience over time. It’s wonderful to gather and create a whole experience for the participants through qigong, meditation, imagery, poetry, writing, and sharing that reflects the depth of the month’s journey.\nWe find a way of balancing intention, presence, and spaciousness that helps the group settle in and feel held as well as allowing for what feels most emergent and alive. I carry a woven basket that contains our portable altar to create sacred space whenever and wherever we arrive for circle. Participants have made offerings for the altar such as sweetgrass and a beautifully carved wooden angel given during chemotherapy.\nThough we meet for only two-and-a-half hours on a Monday afternoon once a month, it’s moving to see how the members of the group feel a sense of seamless continuity. We’ve grown to care for one another and to track each other’s journeys. The capacity to feel more ease, to listen and to dive deep creates inspiration shared by all. A major learning from our experience is the importance of commitment over time to show up fully for circle on the part of the participants and the facilitators. There is a mutuality and reciprocity that develops over time and enriches and deepens how we show up—both in circle and our lives. The sense of safety and spontaneity allows for each of us to share what is true for us, and to know that we will be accepted, honored and celebrated in our sorrow, joy and wholeness.\nOne couple, both skilled musicians, came to circle originally as patient and caregiver, one actively in treatment while the other had a history of cancer. Over the course of our time together, the caregiver developed a new brain tumor and was catapulted into treatment. They had to change the dance in their relationship—to be there in a new way to support one another while being in the throes of their individual journies. During one of our healing circles, they brought a guitar and sang right into our hearts. We were deeply moved by the beauty of the music, the power of love, and the appreciation of how evanescent these moments of meaning can be. (We were also grateful for the box of tissues that have become a fixture in our altar.)\nEach month, participants receive an overview of the next month’s theme. Being able to anticipate the theme creates a keynote for the month that gains momentum, meaning, and clarity, and that guides each of us over time. From the feedback we’ve received from participants, healing circles are transformational as mini-retreats, akin to the longer retreats we offer at Harmony Hill Retreat Center for people with cancer and their families.\nI am grateful for my partner and ally, Linda Covert. Co-facilitation is a dance that calls for listening, flexibility, mutual growth, creativity and the moment-to-moment discernment of knowing when to step in and when to make space. As facilitators, we carefully weave and support the process and the sharing of the group to bring a vibrancy that carries us all through the ongoing rough-and-tumble of life.\nHeader photo by Corrine Bayley", "pred_label": "__label__POS", "pred_score_pos": 0.6093752384185791}
{"content": "Joseph Lofthouse wrote:My land comes to me via word of mouth, and with a handshake... People know that I'm a farmer. They have land that is a burden to them. They wish that someone would take care of it, so they ask me if I'd grow on their land. I turn down more offers than I accept. If I was taking care of any more fields, I'd have to hire help, and that doesn't appeal to me. I paid rent the first few times, but I have since learned that land is a burden to it's owners. Many would even pay me to take care of their land for them.\nTravis Johnson wrote:...but I disagree with door to door approaches being the last resort...\nCrown resource lands may be used for a variety of purposes under a lease, permit, easement or licence that allow the legal occupation or use of the land. Examples include:\n- Remote recreational cottage; - Traditional resource use cabins; - Commercial and industrial operations; and - Wild rice harvesting. Leases are generally longer term dispositions that allocate lands for particular use. Permits are shorter term authorizations that grant access to the land for a specific purpose.", "pred_label": "__label__POS", "pred_score_pos": 0.6307180523872375}
{"content": "Integrated health care (IHC) connects pharmacy, dental, vision, disability, Employee Assistance Program (EAP), and supplemental health plan data to an employer’s medical plan. This allows doctors and other health care providers to share actionable data to better diagnose and treat members, detect coverage gaps, and guide employees toward prevention and care management.\nWhile IHC has been on an upward trajectory since 2016, the findings from the 2020 Integrated Health Care Report, Edition 4 demonstrate that this strategy has effectively become the norm among employers. The majority — 56% — now connect benefits to save money and improve employee health. This represents an 11% increase since 2018.\nThe move to integration: a breakdown by product\nVision and pharmacy are the top products employers are focused on integrating in 2020, followed by dental and disability. EAP and supplemental health were measured for the first time. Both already demonstrate significant importance.\nVision – 75% integrated\nPharmacy – 73% integrated\nDental – 67% integrated\nDisability – 63% integrated\nEAP – 62% integrated\nBelow is a video outlining the key 2020 research findings. To learn more about IHC, reach out to your broker, benefits consultant or insurance company representative. You can also find more information at www.specialtybenefits.info/ihc.", "pred_label": "__label__POS", "pred_score_pos": 0.7354773283004761}
{"content": "The rollercoaster of emotions, driven by uncertainties during the pandemic can create fertile ground for self-doubt, fear, and insecurity.\nFor young people, signs that suggest this can include:\n🔹Mood swings 🔹Change in regular sleep/eating habits 🔹Habits such as nail-biting, thumb-sucking, or hair-pulling/chewing 🔹Physical ailments like stomachaches & headaches.\nIn this camp, they’ll learn:\n🔸How to enhance and protect a healthy self-esteem 🔸Understand the source of their fear, insecurity & self-doubt 🔸Healthy coping skills when dealing with life challenges\nActivities include:\n🔸Therapeutic art 🔸Mask-play 🔸Creative writing 🔸Breathing techniques for confidence", "pred_label": "__label__POS", "pred_score_pos": 0.9926145672798157}
{"content": "Which Cryptocurrency will we use for the \"Internet of Things\" (IoT)?\nThere are billions of devices connected to the Internet. These range from computers, smartphones, home security systems, doorbells and lights to urban infrastructure. These tools and systems can be controlled by connecting them to the Internet. We all have a growing number of these devices in our homes and around us. The\nInternet of Things (IoT) refers to this universe of devices that can be accessed, monitored and controlled via the Internet.\nThe\nInternet of Things offers great potential to make our lives easier and more efficient. A common example is controlling your home lights or temperature via your smart phone. However, the possibilities don't end there. In the near future these machines will not only communicate with each other via the Internet, but they will be able to seamlessly accept payments from each other. Where will we use this technology and what currency will machines use to \"pay\" each other? Examples include your electric vehicle communicating with tolls, charging stations and parking meters. Using IoT enabled technology your car could pay these fees seamlessly over the Internet. What cryptocurrency is likely to be robust enough to handle the potential trillions of transactions that will be occurring on the IoT? Bitcoin as been referred to as the \"currency of the Internet\". However, blockchain technology is slow and requires fees to process. Another issue is that processing slows down with increased users in the system. It is also currently energy intensive. One potential solution is a cryptocurrency called IOTA. It is similar to Bitcoin in that it is based on an online distributed ledger system. However, unlike Bitcoin it does not use blockchain technology. It uses a technology called tangle. IOTA cryptocurrency actually increases its speed of transactions a the transaction volume increases. This system seems ideal for the Internet of things. This innovative technology is already being implemented in cars like the Jaguar Land Rover on a trial bases.\nThe short video below gives a nice explanation of\nIOTA cryptocurrency and Tangle technology", "pred_label": "__label__POS", "pred_score_pos": 0.5386965870857239}
{"content": "CD154-CD40 interactions play key roles in humoral and cellular immune responses. With regard to the latter, ligation of CD40 on endothelial cells upregulates important intercellular adhesion molecules. Activated endothelial cells also regulate leukocyte trafficking into inflammatory sites by secreting chemokines. In this study we asked whether CD154 mediated signals induce human umbilical vein endothelial cells (HUVEC) to secrete neutrophil or peripheral blood mononuclear cell (PBMC) chemoattractants. HUVEC were cocultured with CD154(+) Jurkat D1.1 cells in the presence or in the absence of anti-CD154 mAb or control mAb. Additionally, HUVEC were cocultured with control CD154(-) Jurkat B2.7 cells. Supernatants were harvested after 24 h and chemotaxis assays performed. Supernatants derived from Jurkat cells did not induce either neutrophil or PBMC chemotaxis. Resting endothelial cells produce at baseline some neutrophil and PBMC chemoattractants. However, there was significantly enhanced neutrophil and PBMC chemoattractant activity in supernatants derived from CD154 stimulated HUVEC. The enhanced leukocyte migration was specifically inhibited by anti-CD154 mAb. Anti-chemokine mAbs were used to identify specific chemokines mediating the enhanced leukocyte chemotaxis activity in CD154 stimulated HUVEC supernatants. There was complete or near complete inhibition of enhanced neutrophil and PBMC migration by anti-IL-8 and anti-monocyte chemoattractant protein-1 (MCP-1) mAbs, respectively. Anti-RANTES mAb partially blocked the enhanced PBMC migration, whereas anti-macrophage inflammatory protein-1alpha (MIP-1alpha) mAb had no effect. Utilizing specific ELISAs, we confirmed that CD40 ligation induces HUVEC to secrete IL-8, MCP-1, and RANTES, but not MIP-1alpha. Finally, we present evidence that the effects of CD154-CD40 interactions on HUVEC chemokine production are independent of IL-1beta production. These findings demonstrate that CD154-CD40 interactions induce endothelial cells to produce specific neutrophil and mononuclear cell chemoattractants.\nCopyright 1999 Academic Press.", "pred_label": "__label__POS", "pred_score_pos": 0.7236998081207275}
{"content": "Don’t worry – this time, news is coming from China unrelated to the coronavirus outbreak.\nWith so many people around the world working from home, social distance and quarantining themselves after potential exposure to COVID-19, online searches around cryptocurrencies have become a bump.\nAccording to an available report, the Chinese search engine Baidu has made a significant leap in its searches for “Bitcoin” (BTC). The data index shows that searches for BTC have increased by 183% in the past thirty days, while the number of people searching for information about the cryptocurrency on mobile devices has also skyrocketed.\nThe interest may be related to the theory that a global economic crisis may lead to a growing value for the cryptocurrency as a hedge against the banks.\nWith Google currently blocked in China, Baidu is one of the most popular search engines. However, Chinese netizens are not the only ones with a growing interest in the crypto market.\nGoogle’s search results for BTC in the United States peaked at 30 days on March 13. This was shortly after the cryptocurrency experienced its biggest daily decline in the past seven years, when more than $ 1 billion in longs were liquidated.\nWith much of the world’s population connected more than ever, it is not surprising that many have expressed an interest in Bitcoin. However, the number of search results related to buying the cryptocurrency is significantly higher than those seeking to sell it.\nThis data is somewhat unusual in that many Americans in larger cities are advised to protect their place, with some losing their jobs completely. Bitcoin traders may need to liquidate at least part of their holdings to pay for the daily expenses, yet it seems that many want to buy more.\nThe crypto market has shown that it can be as volatile as traditional when the global economy is facing a pandemic. However, the price of BTC has stabilized after the crash two weeks ago, and traders may want to buy while the price is low.", "pred_label": "__label__POS", "pred_score_pos": 0.5872921347618103}
{"content": "Real Estate Perspective on New Lease Accounting Standards\nBy John Corbett, MAI, ASA, FRICS and Marc R. Shapiro, MAI, MRICS\nKey findings of the report include: Accounting Standards Update 2016-02, Leases (Topic 842) will have an impact on accounting practices across the real estate industry. The most significant change in the new lease guidance requires lessees to recognize right-of-use assets and lease liabilities for all leases, with few exceptions. Lessors and lessees must ensure that their finance teams understand these new guidelines and are prepared to determine the necessary data points, as more rigorous transparency standards now apply.", "pred_label": "__label__POS", "pred_score_pos": 0.998123049736023}
{"content": "4. Writing. Logic will also help you to write more clearly and effectively, for clear writing and clear thinking are a “package deal”: the presence or absence of either one brings the presence or absence of the other. Muddled writing fosters muddled thinking, and muddled thinking fosters muddled writing. Clear writing fosters clear thinking, and clear thinking fosters clear writing. Common sense expects this, and scientific studies confirm it.\nThere is nothing more effective than traditional logic in training you to be a clear, effective, and careful writer. It is simply impossible to\ncommunicate clearly and effectively without thinking clearly and effectively. And that means logic. [Adapted from Peter Kreeft, Socratic Logic]", "pred_label": "__label__POS", "pred_score_pos": 0.8230493664741516}
{"content": "Ruffer Investment Company (RICA) is designed to achieve positive annual total returns (after expenses) of at least twice the Bank of England base rate. The trust invests internationally across a range of asset classes, seeking to hold both growth and protective strategies in an appropriate balance with the aim of generating consistent positive returns and avoiding losses over rolling 12-month periods.\nRICA consists of pools of assets designed to provide different return profiles in various environments. This structure has proven robust in the market sell-off in Q1 2020, with NAV returns basically flat (\nsee Performance). The managers have long argued that structural problems in developed economies – primarily too much debt and too little growth – will ultimately compel governments and central banks to ever more extreme measures to try and inject inflation and nominal growth into the system, and have been positioned accordingly. A sharp shock to the economic system from the spread of COVID-19 seems set to catalyse this, and they believe it will be unlikely to prove politically feasible to unwind ‘temporary’ emergency-support measures.\nAs we discuss in the\nPortfolio section, the managers have taken profits in protective strategies focussed on equity markets and volatility after a substantial rally in these derivatives. However, they continue to hold protection in credit markets, which should offer asymmetric protective characteristics should the current crisis evolve into a full-blown credit crisis.\nWith the protective strategies having largely offset losses in the equity holdings, RICA’s NAV has remained resilient. However, the\ndiscount has moved slightly wider, but seems to have consistently attracted buyers when around current levels (c. 6% as of 31/03/2020). Kepler View\nRICA has fulfilled its primary objective in the recent, turbulent, weeks. In the ‘Goldilocks’ investment epoch, it may have been tempting to disregard many of the protective strategies as requiring a spike in volatility which the ‘Fed put’ would essentially preclude. However, as seen in both Q4 2018 and Q1 2020, a permanently becalmed state is not a realistic expectation for asset markets. We had previously highlighted that these protective strategies with asymmetric pay-off structures would likely ultimately prove highly attractive, and thus it has proven. The managers’ trading activity around these in recent weeks seems sensible, booking profits from assets unlikely to offer much further appreciation whilst retaining assets which retain substantial upside if the current pandemic and associated economic shutdown develops into a wider systematic credit event.\nHaving protected on the downside, the managers have also identified attractive potential convexity in inflation-linked bonds. The short-term direction of inflation appears uncertain, with a tsunami of government borrowing meeting a likely chasmic dearth of private spending, but, should these ‘temporary’ government programs prove hard to reverse, governments will be directly injecting money into the economy. RICA’s portfolio remains well-balanced; the\ndiscount does not seem to offer the prospect of a substantial uplift, but in our view is unlikely to widen substantially. Overall RICA should continue to offer resilience as part of a balanced portfolio, with the potential for substantial upside if the managers’ base case macro scenario materialises.\nbull bear Has offered protection in recent sell-off, and should continue to do so in future Will likely lag equity products if we see a sharp market recovery Should offer substantial upside if inflation picks up materially Deflation remains a risk to absolute returns Hedges are well balanced to growth opportunities Dividend yield is likely to be low", "pred_label": "__label__POS", "pred_score_pos": 0.6069387793540955}
{"content": "When I lost my leg, I sued the construction company that had been involved in the site where the accident occurred. My prosthetist was charged with projecting my prosthetic needs for the rest of my life.\nThe figure he gave my attorney would not have kept me in prostheses for five years, let alone the fifty some years of my life expectancy. When I became a prosthetist I saw a need for a systematic approach to projecting the prosthetic needs of the amputee.\nExpert Witness Testimony\nI have provided expert witness testimony in over 30 cases in the past twenty years. I have been on the stand and withstood numerous depositions. I have worked with sloppy legal teams and others who left no stone unturned in their pursuit of information that improved their client’s case. My case history record is balanced with over 40% of the cases for the defense.\nDefining Needs Analysis for Prosthetic Devices\nI create a personalized Needs Analysis that bases the replacement of prosthetic devices on the amputee’s activity level. I base the premise of the report on medical records or deposition testimony which is all part of the court record. I minimize conclusions based solely on my experience. Being an amputee myself, I help any team project an accurate portrayal of realistic expectations of amputee life.", "pred_label": "__label__POS", "pred_score_pos": 0.5335109829902649}
{"content": "When solvents become contaminated or dirty, they require careful distillation and recycling. Proper solvent recovery and recycling is not only essential to the environment, it's critical for your business — reducing the need for new solvent production can can substantially reduce your waste management costs.\nWith Solvent Recycling Systems, 98% of your solvent/chemical waste disposed of ends up reused. We help you accomplish this by increasing the efficiency of degreasing and cleaning operations through our patented solvent distillation equipment.\nCost savings are immediate and substantial: Greatly reduce the volumes of solvents, associated handling costs for waste removal, and unnecessary storage costs for both fresh solvent and waste solvent.\nThe reduction in waste generation can make a critical difference in an operation's compliance status, often keeping levels low enough to reduce or prevent the need for additional paperwork, recordkeeping, and reporting.\nWe can help you achieve true value from your contaminated solvents.", "pred_label": "__label__POS", "pred_score_pos": 0.7586618661880493}
{"content": "EspañolNo, it is not a misprint. I did not mean for the title to be the “Angst ‘for’ Freedom.”\nA pioneering 1941 work in social psychology by social scientist Erich Fromm,\nEscape from Freedom (also known as The Fear of Freedom), explores our relationship with freedom, and in particular, the personal consequences of its absence under authoritarian rule. Fromm examines how, when freed from authority, we are often left with feelings of confusion.\nThe insights offered by social scientists in this field are relevant to our understanding of the adaptation challenges of those that have been deprived of individual liberties for decades, and to the challenges faced by post-totalitarian societies.\nPost-totalitarism does not imply democracy. In academic jargon, post-totalitarism refers not just to a historical period of time after totalitarian rule. Post-totalitarism is a specific political category for regimes that still seek control over its citizenry after having lost the legitimacy accruing from its official ideology or charismatic leadership.\nIn this sense, Cuba, with a discredited ideology and elderly historic leadership, may soon enter a post-totalitarian stage.\nBy definition, totalitarianism pursues total control of political, economic, and social domains. Choice is eliminated. For those not used to exercising freedoms, and inexperienced in the know-how of choosing, an overload of options often leads to poor decisions when suddenly confronted with the extreme stimuli of the plethora of choices available in free societies.\nStudies in economics and marketing corroborate the idea of the paralyzing and anxiety-producing effects of having too many choices.\nFor many recent Cuban immigrants, the initial exposure to the many choices and decisions required by a free society results in increased levels of anxiety and hopelessness. These conditions are also observed in post-totalitarian societies. Following the collapse of the Soviet Union, numerous studies have documented this phenomenon of the fear of freedom. When memories of communist repression faded in former Soviet-bloc countries, some longed for the perceived simplicity of communist rule.\nFromm’s early work differentiated between “freedom from” (negative freedom) and “freedom to” (positive freedom). In the political context, negative freedom refers to freedom from institutional oppression. Positive freedom refers to freedom to develop one’s potential. Once free from oppression, we must learn to make responsible choices in the pursuit of our dreams.\nIt is by choosing that we demonstrate who we are, and what we care about. Cuban immigration attests that, without choice, life is nearly unbearable. This is what I call the angst of freedom.\nFromm’s work suggests that when nations escape from institutional totalitarian rule (when they experience negative freedom), they have a propensity to submit to authoritarian rule; to replace one tyranny for another. He argues that such societies are predisposed to replace the old totalitarian order with an authoritarian regime as a way of coping with the overwhelming choices of positive freedom (“freedom to”).\nPost-totalitarian nations often choose a new authoritarian regime that will have a different external appearance but will perform the same function of eliminating the anxiety and uncertainty of having to choose freely. On this basis, some argue that democracy is not so desirable for Cuba and propose governance of enlightened or benevolent despotism. The legitimization of the Castro regime under the new US-Cuba policy offers a subtle example of this view.\nAs a political category, post-totalitarism is incompatible with civil and political rights. And these rights are fundamental, because without political rights the citizenry cannot assert any rights. Without political rights, economic rights lack foundation and are not rights but permits that can be revoked. Thus, support for a post-totalitarian, non-democratic regime implies allowing the regime to impose an illegitimate order.\nThe remedy for the anxiety effects of being free to choose is not some form of choice-limiting, “Castro-light” governance. The antidote is a citizenry fully cognizant of, and free to exercise, its political and economic rights.\nDemocratic governance and free markets are the only systems designed to ensure citizen participation in political and economic affairs. And it is that participation that teaches us to appreciate diversity, to welcome the challenges of our choices, and to transform the angst of freedom into the love of freedom.", "pred_label": "__label__POS", "pred_score_pos": 0.5942655801773071}
{"content": "A special thank you to these Trusted firms for supporting the investor.com mission and ongoing research! Are you a Trusted fiduciary? Join these firms today.\nThe investor.com Trusted badge is awarded to the advisory firms that meet strict regulatory requirements.\nUnlike doctors and lawyers, not all financial professionals act as fiduciaries when providing Americans financial advice. Financial advisors have not one, but three possible regulatory classifications.\nUsing over 500,000 data points collected directly from the SEC, the investor.com Trust algorithm surfaces the right questions Americans should ask their financial advisor.", "pred_label": "__label__POS", "pred_score_pos": 0.9963799118995667}
{"content": "Despite a major setback due to the pandemic, the lubricants market in ASEAN region is very dynamic and presents strong growth prospects over the forecast period. Overall, growth is expected to be driven by the consumer segment, followed by the commercial and industrial segments. Government regulations and policies, COVID-19’s impact in the short term, consumer purchasing power, government spending on key industries, and international trade and commodity prices are some of the factors that can critically impact industrial and commercial automotive lubricants segments over the forecast period. Learn about this dynamic market from the upcoming webinar.\nThe insights are sourced from Kline’s report, Opportunities in Lubricants: ASEAN Market Analysis published October, 2020. The study provides a review of market trends and supply/demand drivers, enabling industry participants to capitalize on these trends.\nWith this webinar, attendees will gain key insights into the lubricants markets of eight major ASEAN countries.\nSpecifically, the webinar will help to:\nGain key information on demand for lubricants by product, country, and industry\nLearn about the competitive landscape Discover how the market is impacted by the current C-19 pandemic Gain insights on key trends, challenges, and opportunities", "pred_label": "__label__POS", "pred_score_pos": 0.9999668598175049}
{"content": "The Department has published a guide titled “Quick Guide to CDBG Eligible Activities to Support Infectious Disease Response.” The Department notes that “[g]rantees should coordinate with local health authorities before undertaking any activity to support state or local pandemic response.” The guide also notes that the CDBG activities may fund a range of eligible activities that prevent and respond to the spread of coronavirus.\nThe guide can be found here.", "pred_label": "__label__POS", "pred_score_pos": 0.9999054074287415}
{"content": "Tributação das entidades de previdência complementar sob a ótica da teoria da maximização de riquezas de Richard Posner DOI: http://dx.doi.org/10.18836/2178-0587/ealr.v2n1p141-154 Abstract\nThe growth of investment in private plans has brought an opportunity for reflection on the role of taxation on this important producer of domestic savings. The new role of the Brazilian state seeking to increase the tax burden as the key to maintaining economic development. This paper aims to present a relationship between the public pension crisis, the growth of pension funds and the role of taxation, particularly income tax in the three phases of impact: contributions, applications and rescues. This study will be conducted from the critical perspective of theory of justice of Richard Posner on the Field of Economic Analysis of Law.\nKeywords\nLaw & Economics; Tax Law; Supplementary Pension Plan; Normative Analysis; Richard Posner\nFull Text:PDF (Português (Brasil))\nDOI: http://dx.doi.org/10.18836/2178-0587/ealr.v2n1p141-154\nEconomic Analysis of Law Review - ISSN 2178-0587", "pred_label": "__label__POS", "pred_score_pos": 0.513569712638855}
{"content": "Ellis Smith, with American Cannabis Company, and Dr. Mitch Day, Scientist and Entrepreneur, hosted a panel of experts to discuss germplasm and micropropagation within the cannabis industry.\nAs a renowned subject matter expert on micropropagation and genetic analysis, Dr. Mitch Day knows there’s an unsolved problem in the cannabis industry: a significant lack of public germplasm repositories. Day believes cultivators can benefit from micropropagation with disease-resistant cloning and large-scale cultivar storage for advanced breeding programs. In this webcast, Day discusses the benefits, challenges, and importance of germplasm with cannabis industry experts Dylan Wilks, founder and CTO of Orange Photonics, as well as Dr. Max Jones, Assistant Professor at the University of Guelph, Gosling Research Institute for Plant Preservation.", "pred_label": "__label__POS", "pred_score_pos": 0.941527783870697}
{"content": "CAPR Board approves Clinical Component Innovation RoadmapOctober 26, 2020\nOn October 21, CAPR staff presented a Clinical Component Innovation Roadmap to the CAPR Board of Directors and non-board Canadian physiotherapy Registrars. We are pleased to announce that the Board has approved immediate implementation of this Innovation Roadmap, a summary of which is shared below.\nAdapting to “Covid Times”\nCAPR will embrace new innovations to deliver a viable Clinical Component in 2021. The Clinical Component CAPR delivers in 2021 will be:\na “virtual” exam (i.e., experienced by candidates in a digital environment); a “touchless” exam (i.e., candidates will not be in the same room as standardized clients); delivered with greater annual frequency than ever before to address the backlog created by the cancellation of 2020 exams in addition to typical demand; recorded to safeguard fairness and validity.\nGuiding Principles\nImplementation of CAPR’s 2021 Clinical Component exam will be guided by three principles;\nthe 2021 Clinical Component will: leverage existing exam content and structure, wherever possible, and adhere to the existing PCE blueprint; assess a broad spectrum of entry-to-practice competencies and clinical reasoning skills; be deliberately “pandemic-proof” by assuming widespread facility closures, physical distancing requirements and restrictions on travel across provincial boundaries.\nAccelerating CAPR’s Innovation Agenda\nCAPR’s innovation agenda began in earnest in 2019 and prior to the arrival of Covid-19, the CAPR Board of Directors approved innovations to the Clinical Component. The necessity to innovate the Clinical Component immediately allows CAPR to fast track many of these proposals, including:\nremoving all written elements of the Clinical Component (i.e., eliminating the written portion of all 5+5-minute couplet stations); eliminating the “Number of Stations” criterion (i.e., candidates will no longer be required to pass a pre-determined number of stations to pass the exam). reducing the number of stations from 16 to 12. (i.e., the exam will now be comprised of six 10‑minute stations and six five‑minute stations).\nMaintaining our Commitment to Validity and Reliability\nCAPR will maintain our commitment to delivering a valid and reliable exam, even in the context of massive change. We will ensure that the 2021 Clinical Component is both valid and reliable by:\nconfirming that any changes to the exam structure are psychometrically defensible; leveraging existing clinical stations that have demonstrated acceptable performance; having all content modifications reviewed by physiotherapy content experts in a two-stage process (i.e., CAPR’s Clinical Test Development Group comprised of practicing physiotherapists); initiating focus groups and the pre-testing of practice stations using recent licensees and examiners; delivering comprehensive 2021 clinical exam training with Examiners and Standardized Clients; delivering a robust orientation program for candidates challenging the 2021 Clinical Component; recording each exam to enable the confirmation of standardization and fairness.", "pred_label": "__label__POS", "pred_score_pos": 0.7989434003829956}
{"content": "Cambridge-based architects Samskara had to meet a challenging brief with a new building that, at an internal floor area of 380m\n2, was only half the size of the old building, yet was required to be a building of note – ‘significant and sustainable’ and capable of engaging the community, with access to a number of sports. Low in maintenance and efficient to run, the new building must sit well on the open site.\nSamskara responded with a contemporary single-storey design that illustrates sustainable credentials throughout. Built around a timber frame, clad externally in cream linear brickwork, the building is topped by an extravagant inverted pitch roof structure that overhangs the building on all sides to provide protection and prevent unauthorized access onto the structure – a key requirement of the client brief.\nPurposely chosen to be erected quickly, the timber frame design allowed the brick outer skin to be constructed much later in the build programme, accommodating the brick’s lead time, and taking this crucial element off the critical path. This avoided any possible build delays and enabled the specialist contractors to achieve facades of exceptional quality and precision.\nIbstock’s Linear Natural Cream bricks provide a stunning contrast to the dark grey plinth and roof covering, sitting the building sympathetically alongside the surrounding architecture. The long, narrow bricks enhance the linear aspect of the building, being laid immaculately in stack bonded format to add a unique and distinctive structure to the facades. Samskara specified and detailed the four available brick lengths to co-ordinate the elevations and fit the building perfectly, without cutting, to maintain the ‘engineered’ appearance of the elevations.\nThis technical aspect of the plan form, combining linear format with a repeated transverse structure, was determined with reference the England and Wales Cricket Board, Football Foundation and Sports Council recommended planning guidelines, and met the client’s desire for a flexible structure, capable of accommodating the addition of changing rooms or expanded facilities in the future.\nExternally, subtle design details, such as a hand-shake above the entrance, sight screens on the facades and stumps and bails of the main façade, ensure that the building reflects the sports it serves, whilst internally, a thoughtful layout, with changing facilities deliberately separated from public/spectator spaces, a security lobby and ramped disabled and wheelchair access throughout the building, make it the perfect backdrop against which to rebuild Ransomes’ former sporting reputation.", "pred_label": "__label__POS", "pred_score_pos": 0.5574741959571838}
{"content": "Encounters with Alumni from Greater China Professor Dennis Lo (Christ Church, 1986; Hertford 1990)has recently been elected a Fellow of the Royal Society, joining the likes of prominent scientists such as Isaac Newton and Charles Darwin. The Royal Society recognises Professor Lo’s discovery of circulating fetal nucleic acids in the plasma of pregnant women, creating a paradigm shift in non-invasive prenatal diagnosis, for example for Down’s Syndrome. From bench-side to signing in the Royal Society Charter Book with the historic quill-pen, Professor Lo remarked, ‘I am most delighted to receive this honour, which is one of the most treasured that a scientist can receive.”\nOver the past 14 years, Professor Lo’s research team has achieved many breakthroughs in the diagnostic applications of circulating fetal nucleic acids and in understanding its fundamental biology. For example, Professor Lo has recently demonstrated that the entire fetal genome is present in maternal plasma and has outlined the conceptual framework for non-invasive fetal genome scanning.\nProfessor Lo is currently the Director of Li Ka Shing Institute of Health Sciences and Li Ka Shing Professor of Medicine and Professor of Chemical Pathology at The Chinese University of Hong Kong.\n--- Written in August 2011---", "pred_label": "__label__POS", "pred_score_pos": 0.9552362561225891}
{"content": "What this skeleton told us: Evidence\nA middle-aged or older man and 179 cm tall (5 feet 10 inches). All his teeth had been lost after death. The grave was likely disturbed by the later burial of skeleton 176 and it may have been this disturbance that led to the tooth loss.\nInterpretation of the evidence\nIn Anglo-Saxon Britain, it is likely that if a man survived childhood, he could expect to live a fairly long life, at least into middle-age, provided he maintained good health and was not killed in battle. However, we should remember that humans are very good at adapting to challenging times! This older man was substantially above average height for the period and died at a relatively advanced age, indicating that he was well-nourished and in good general health.\nDenisc\nDanish, Viking.", "pred_label": "__label__POS", "pred_score_pos": 0.9131264090538025}
{"content": "Occupied Palestinian Territory (OPT)\nThe OPT consists of the West Bank (including East Jerusalem) and Gaza. Some 4.5 million Palestinians live in the OPT (2.7 million in the West Bank and 1.8 million in Gaza). The fulfilment of a two-state solution to the Israeli-Palestinian conflict would see the creation of a sovereign and unified Palestinian state on this area, with East Jerusalem as its capital, based on the pre-June 1967 lines (the borders that existed prior to Israel's occupation of the West Bank and Gaza in June 1967).\nIsrael occupied the West Bank and Gaza during the 1967 war. Between 1976-1993, it administered the OPT through a system of Palestinian “Village Leagues”. The launch of the 1993 Oslo peace process between Israel and the PLO, however, led to their replacement with a newly created Palestinian Authority (PA), the return of the previously exiled PLO, and a shift in the Palestinian liberation movement’s centre of gravity, away from the refugee camps and diaspora, to the OPT.\nThe 1993 Oslo Accords have resulted in the gradual fragmentation of the OPT. As part of a four-year interim phase supposedly leading to a final status agreement, the West Bank was divided into three areas with differing jurisdictional arrangements: Area A (17.2 per cent) under full PA control; Area B (23.8 percent) under PA civil control and Israeli security control; and Area C (59 per cent) under full Israeli control. The Oslo peace process also saw a surge in Israeli settlement building. Today, the West Bank is perforated by over 200 Israeli settlements, dozens of “outposts” and military bases, along with a network of restricted roads and checkpoints. In total, over 588,000 Israeli settlers reside in the OPT.\nThe West Bank and Gaza have been politically split since the intra-Palestinian fighting that erupted after Hamas’s victory in the 2006 legislative election. Since then, Hamas has controlled Gaza, while the PA remains in the West Bank. This has resulted in the emergence of two parallel systems of Palestinian governance, despite numerous intra-Palestinian reconciliation attempts. Gaza has also been under an Israeli air, sea, and land blockade since then, limiting the ability of Palestinians to travel and trade with the West Bank, and creating severe social, economic, and humanitarian hardships for Gazans.", "pred_label": "__label__POS", "pred_score_pos": 0.6247870922088623}
{"content": "Abstract\nEukaryotic initiation factor 4E (eIF4E) has central roles in the control of several aspects of post-transcriptional gene expression and thereby affects developmental processes. It is also implicated in human diseases. This review explores the relationship between structural, biochemical and biophysical aspects of eIF4E and its function in vivo, including both long-established roles in translation and newly emerging ones in nuclear export and mRNA decay pathways.\nPublication types Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. Review MeSH terms Active Transport, Cell Nucleus Eukaryotic Initiation Factor-4E / chemistry Eukaryotic Initiation Factor-4E / metabolism Eukaryotic Initiation Factor-4E / physiology* Gene Expression Regulation* Protein Binding Protein Biosynthesis RNA Cap-Binding Proteins / chemistry RNA Cap-Binding Proteins / metabolism RNA Cap-Binding Proteins / physiology* RNA Stability Substances Eukaryotic Initiation Factor-4E RNA Cap-Binding Proteins", "pred_label": "__label__POS", "pred_score_pos": 0.7395944595336914}
{"content": "Abstract\nBackgroundHigh-throughput sequencing has enabled detailed insights into complex microbial environments,including the human gut microbiota. The accuracy of the sequencing data however,is reliant upon appropriate storage of the samples prior to DNA extraction. The aim of thisstudy was to conduct the first MiSeq sequencing investigation into the effects of faecal storageon the microbiota, compared to fresh samples. Culture-based analysis wasalso completed.MethodsSeven faecal samples were collected from healthy adults. Samples were separated intofresh (DNA extracted immediately), snap frozen on dry ice and frozen for 7 days at -80°Cprior to DNA extraction or samples frozen at -80°C for 7 days before DNA extraction. Sequencingwas completed on the Illumina MiSeq platform. Culturing of total aerobes, anaerobesand bifidobacteria was also completed.ResultsNo significant differences at phylum or family levels between the treatment groups occurred.At genus level only Faecalibacterium and Leuconostoc were significantly different in thefresh samples compared to the snap frozen group (p = 0.0298; p = 0.0330 respectively). Diversityanalysis indicated that samples clustered based on the individual donor, rather thanby storage group. No significant differences occurred in the culture-based analysis betweenthe fresh, snap or -80°C frozen samples.ConclusionsUsing the MiSeq platform coupled with culture-based analysis, this study highlighted thatlimited significant changes in microbiota occur following rapid freezing of faecal samplesprior to DNA extraction. Thus, rapid freezing of samples prior to DNA extraction and culturing,preserves the integrity of the microbiota.\nKeywords gut microbiota", "pred_label": "__label__POS", "pred_score_pos": 0.9495539665222168}
{"content": "Tenants are calling on the state to unveil the identities of various landlords accused of unlawfully deregulating rent-stabilized apartments.\nA petition filed this month claims the New York State Division of Homes and Community Renewal is wrongly hiding the identities of landlords who allegedly deregulated rent-stabilized apartments while receiving tax benefits from the J-51 abatement program, according to the New York Daily News. Under the program, landlords must keep all units rent-stabilized.\nThe state sent letters to landlords in 2016 warning that they could lose their benefits if they don’t keep apartments rent-stabilized. Robert Grimble and Shaina Weissman, attorneys who have represented tenants in rent disputes, claim in the petition that the state refused to provide a list of the landlords who received the letters when they filed a public records request.\nCommunity Renewal maintained that fulfilling the request “would interfere with law enforcement.”\n“Rather than oblige landlords to re-stabilize illegally deregulated units and reset the rents to the correct amounts, the J-51 initiative merely sent them letters asking them to re-stabilize their apartments,” said representatives for the Housing Rights Initiative, a tenant advocacy group that signed onto the petition. [NYDN] —\nKathryn Brenzel", "pred_label": "__label__POS", "pred_score_pos": 0.8895363807678223}
{"content": "Thames Valley Police is urging people to remain cautious after an elaborate scam has resulted in victims losing a total of £15,000.\nA man, described as being of Mediterranean appearance, in a dark coloured car, has been approaching people asking for directions to Heathrow Airport. He claims to be a fashion designer with Giorgio Armani and that he has excess stock he is unable to take back to Dubai with him due to the high cost. He asks people to lend him money to cover the cost of his car hire on the promise that the money will be paid back. He encourages the individuals to provide their bank account details and will then drive them to the bank where the money is withdrawn and handed over.\nThe contact details passed over to the individuals turn out to be false and no money is ever paid back.\nThis scam results in a significant financial loss and poses a risk to the victim’s safety by agreeing to get in a car with a stranger. Where personal details including bank details have been handed over, this also leaves the victim open to identity fraud.\nThames Valley Police are urging the following:\nNever agree to lend a stranger money, no matter how elaborate and believable their story may be. Never agree to purchase or accept items from a stranger – These items may be stolen and you could be implicated as being involved in handling stolen goods. Never reveal personal details to a stranger, especially banking details. Never agree to get in a stranger’s car, no matter how friendly and trustworthy they may seem.\nContact your bank immediately if you think you’ve fallen for a scam and report it to Action Fraud. Call 999 in an emergency.\nFor more information, visit the national Take Five to Stop Fraud (https://takefive-stopfraud.org.uk/) campaign.", "pred_label": "__label__POS", "pred_score_pos": 0.8880991339683533}
{"content": "The US National Highway Traffic Safety Administration (NHTSA) has granted Nuro temporary exemption from certain low-speed vehicle standards for its driverless electric delivery vehicle, the R2.\nThe Mount View, California-based robotics company has designed the R2 to have no human occupant and operate exclusively using an automated driving system. The R2 includes the same automated driving system as Nuro’s previous vehicle but does not have certain features, including mirrors and a windshield. Nuro is permitted to produce and deploy no more than 5,000 R2s during the two-year exemption period.\nNHTSA stated that exemption will not lower the R2’s safety, but it is in the public interest to maintain greater oversight of the R2 than typical for an exempt vehicle.\nExemption comes with conditions including mandatory reporting of information about operations and required outreach to the communities where the R2 will be deployed. Nuro intends to use the vehicles for local delivery services for restaurants, grocery stores and other businesses.\nElaine Chao, US secretary of transportation said, “Since this is a low-speed, self-driving delivery vehicle, certain features that the Department has traditionally required – such as mirrors and a windshield for vehicles carrying drivers – no longer make sense.”\nJames Owens, NHTSA acting administrator added, “NHTSA is dedicated to facilitating the safe testing and deployment of advanced vehicle technologies, including innovative vehicle designs, which hold great promise for future safety improvements. As always, we will not hesitate to use defect authority to protect public safety as necessary.”", "pred_label": "__label__POS", "pred_score_pos": 0.5900113582611084}
{"content": "Since I was\ndiagnosed with multiple autoimmune diseases five years ago, I express what some might call an inappropriate enthusiasm anytime I meet someone with an autoimmune disease. I like to call this the \"ME TOO\" factor (CAPS LOCK intentional).\nHere's a snapshot of a real-life conversation that happened when I ordered gluten and dairy free cupcakes at a local bakery:\nMe: \"I'll have two of the gluten and dairy free cupcakes.\" Bakery employee: \"Those are delicious. I eat them all the time.\" Me: \"Really? Can I ask why you're gluten and dairy free?\" Bakery employee: \"I have Crohn's Disease.\" Me: \"NO WAY! ME TOO!\"\n*onslaught of questions*\nWhen were you diagnosed?\nWhat medicine do you take?\nWho's your doctor?\nHow has the disease impacted you?\nDoes your diet help?\netc. etc.\nWhile the bakery employee seemed slightly overwhelmed by my enthusiasm, a sense of relief and excitement washed over her as we discussed our experiences and even discovered that in addition to sharing the same diet, we also shared the same doctor.\nIt's a wonderful feeling to be able to talk to someone who just \"gets it\". Someone who understands that it's not just a stomachache. Someone who understands that I'm not just tired. Someone who knows what it means to be a\nSpoonie.\nWhen I get excited to hear someone else has an autoimmune disease, it's not because I'm happy they have endured pain and suffering, it's because I'm excited to connect with someone who gets it. Someone who gets me. It opens up an opportunity for me to support a fellow patient enduring a difficult battle and collectively share our stories.\nEvery time a patient opens up and shares their story, they have the power to make a difference. Sharing your story not only offers support for fellow patients, but it provides answers and awareness which are particularly important for patients battling autoimmune diseases. We often rely on each other for answers our doctors can't give us and awareness is still remarkably low considering there are 50 million Americans battling autoimmune diseases.\nSo if you have the \"ME TOO\" Factor, don't be ashamed. Be proud. Be excited. Ask questions. Share your story. Make a Difference.", "pred_label": "__label__POS", "pred_score_pos": 0.7527840733528137}
{"content": "What is an Immunity Passport?\nOn-Site Staff\nMay 25, 2020\nGovernments are currently considering implementing requiring “immunity passports” to allow those with antibodies against COVID-19 to return to work and travel.\nThis assumes that a positive antibody test means prolonged immunity against COVID-19. However, there is insufficient evidence at this point to assure that this is true. It is likely that having antibodies give some immunity and more testing will lead to more answers on the details needed to implement this on a large scale.\nEthicists argue that requiring a positive antibody test for individuals to resume normal life, including work, may have unintended consequences. First, this may lead individuals to behave differently in regards to safety measures to prevent the spread of COVID-19. When people believe they are immune to COVID-19, they may stop wearing masks or may start traveling and may end up getting COVID-19 if the antibody test gave a false positive or if the antibodies did not last, or the levels of the antibody were not high enough. Secondly, this may lead to people trying to get COVID-19 so that they are allowed to return to normal life. Third, there is a chance for injustice due to fewer medical resources for testing available for those with lower socioeconomic status. Therefore, not permitting those to travel without antibodies can result in more problems. Additionally, without understanding the length and level of immunity needed, having possible immunity that lasts less than the amount of time needed to achieve herd immunity may not ultimately be protective. A study of four coronaviruses that cause the common cold demonstrated a significant decrease in immunity after six months. Experts estimate that without a vaccine, it may take 18-42 months to achieve herd immunity. To have a better understanding of how immunity to COVID-19 works, more research, and more COVID-19 antibody testing is needed.\nReferences:\nEdridge, A. W. D., Kaczorowska, J., Hoste, A. C. R., Bakker, M., Klein, M., Jebbink, M. F., … van der Hoek, L. (2020). Human coronavirus reinfection dynamics: Lessons for SARS-CoV-2. doi: 10.1101/2020.05.11.20086439 Kirkcaldy, R. D., King, B. A., & Brooks, J. T. (2020). COVID-19 and post infection immunity: Limited evidence, many remaining questions. Journal of the American Medical Association, E1-E2. doi: 10.1001/jama.2020.7869 Moore, K. A., Lipsitch, M., Barry, J. M., & Osterholm, M. T. (2020). COVID-19: The CIDRAP viewpoint. Retrieved from Phelan, A. L. (2020). COVID-19 immunity passports and vaccination certificates: scientific, equitable, and legal challenges. The Lancet, 395(10237), 1595-1598. Persad, G. & Emanuel, E. J. (2020). The ethics of COVID-19 immunity-based licenses (“Immunity Passports”). Journal of the American Medical Association, E1-E2. doi: 10.1001/jama.2020.8102", "pred_label": "__label__POS", "pred_score_pos": 0.6054261326789856}
{"content": "Mind-body practices are techniques designed to enhance the mind's positive impact on the body. These techniques practices include behavioral, psychological, social, expressive, and spiritual approaches.\nAwareness of the mind-body connection is certainly not a new idea, but it may feel unfamiliar to some in the West, where the mind and body has been traditionally viewed as distinct entities for several centuries. However, this view is rapidly changing as researchers scientifically prove the complex links between the mind and body.", "pred_label": "__label__POS", "pred_score_pos": 0.9948052167892456}
{"content": "What is the cause of the heat generated by Varnish Wire in use, and how can we reduce the heat generated by these varnish wire and use them more safely?\nVarnish wire will heat up when passing through a certain load current. With the increase of load current, the surface temperature of the wire will be higher. If it is not handled in time, the consequences can be imagined. The conductor resistance of the electric wire does not meet the requirements, causing the electric wire to generate heat during operation. Improper wire selection causes the conductor section of the used wire to be too small, resulting in overload phenomenon during operation. After long-term use, the heating and heat dissipation imbalance of varnish wire causes the heating phenomenon. The wires are arranged too densely during installation, the ventilation and heat dissipation effects are not good, or the wires are too close to other heat sources, which affects the normal heat dissipation of the wires and may also cause the wires to generate heat during operation. Joint manufacturing technology is not good, crimping is not tight, resulting in excessive contact resistance at the joint, which will also lead to wire heating. Varnish wire interphase insulation performance is not good, resulting in low insulation resistance and heat generation during operation.\nIn a word, when you use varnish wire, you must do a good job of protecting them. After all, the safety of electrical appliances is very important. It not only affects the use effect of the entire electrical appliances but also causes some hidden dangers to the safety of users. I hope you can pay attention to these matters when using electrical appliances.", "pred_label": "__label__POS", "pred_score_pos": 0.5267629027366638}
{"content": "CHEYENNE, Wyo. (AP) — The coal industry was already hurting before the coronavirus, and the pandemic has made things much worse.\nLockdowns have shut off lights in offices and schools, sapping demand for electricity provided by coal-fired power plants.\nCoal production in the U.S. is now expected to drop 25% in 2020.\nThe federal government hasn’t acted on the industry’s request for $822 million in relief or a union’s concerns about the safety of miners at risk of catching the virus.\nThe worldwide decline in electricity consumption has resulted in at least one benefit — clearer skies and lower pollution.", "pred_label": "__label__POS", "pred_score_pos": 0.9369259476661682}
{"content": "Greater Philadelphia has a diverse community of employers with a growing need for technology talent. As we look towards solutions to address the current and future demand for these workers, we are focused on executing a collective strategy to attract, develop and retain workers to grow the region’s profile as a hub of innovation employment and talent.\nThe CEO Council is taking action to address this need by executing a communications campaign designed to attract mid-level technologists to the region while also working to retain the experienced tech workers who already call Greater Philadelphia home.\nGreater Philadelphia has improved its ability to retain its college graduates graduates in recent years, providing an ample supply of early-career professionals across industries. Retaining and attracting mid-career talent, however, is key to maintaining a robust and experienced high-tech workforce. The Tech Talent campaign focuses on:\nRecognizing Greater Philadelphia as a high-tech employment hub based on the region’s abundance and diversity of opportunities. Promoting the region’s many lifestyle benefits to potential relocating mid-level tech workers throughout the United States to encourage them to live and work in Greater Philadelphia. Retaining and engaging mid-level tech talent currently working in Greater Philadelphia and encouraging them to become ambassadors for the campaign.", "pred_label": "__label__POS", "pred_score_pos": 0.5995181798934937}
{"content": "Active Filters:\nLocation » The Americas\nDisplaying 3 articles.\nRelief and development organizations use various methodologies to map populations, households and individuals that are vulnerable to different shocks – economic and resource shocks, natural disasters and climate change, conflict and violence, health crises and…\nThis note sets out the role of the United States export-import bank, the official US export credit agency, and explores the significance of its role in filling gaps in international trade finance.\nThe Millennium Challenge Corporation (MCC) aims to deliver assistance to underdeveloped countries with a focus on good policy, country ownership and developmental results. This note describes how MCC forms partnerships with highly underdeveloped countries and…", "pred_label": "__label__POS", "pred_score_pos": 0.8344703316688538}
{"content": "Abstract\nAccess to the epicardial space is fundamental to several cardiac procedures. While traditional indications include catheter ablation of ventricular arrhythmias and accessory pathways, novel indications include left atrial appendage occlusion, esophageal protection, mapping and ablation during atrial fibrillation procedures, implantation of epicardial pacing leads, and phrenic nerve displacement to facilitate safe ablation of atrial and ventricular arrhythmias. Accessing the epicardial space safely is a major challenge requiring intimate knowledge of cardiac anatomy, extensive training, and expertise. Over the past years, multiple technological advances have led to significant improvements in epicardial access success and safety. Important examples of such advances include CO\n2 insufflation through the coronary sinus or the right atrial appendage, pressure sensor needle, computed tomography, cardiac magnetic resonance, and electroanatomic mapping–guided epicardial access. In addition, we provide special maneuvers to minimize inadvertent right ventricular perforation. Keywords Arrhythmias Epicardial ablation Epicardial access Phrenic nerve protection Right ventricular perforation Techniques ASJC Scopus subject areas Cardiology and Cardiovascular Medicine Physiology (medical)", "pred_label": "__label__POS", "pred_score_pos": 0.8270462155342102}
{"content": "Vehicles under about 10,000 pounds cause the same level of pavement damage. These include passenger cars, pickups, and SUVs. Vehicles more than 10,000 pounds cause more damage that increases with weight. Those vehicles pay diesel taxes and weight taxes for road maintenance. The RUC research is focusing on passenger vehicles weighing less than 10,000 pounds because this vehicle category is quickly growing more fuel-efficient and eroding gas tax revenue.", "pred_label": "__label__POS", "pred_score_pos": 0.7570987343788147}
{"content": "Diamond & Minerals segment\nRio Tinto’s (RIO) Diamond & Minerals segment is going through a rough patch. While titanium dioxide’s feedstock and uranium’s demand remain weak due to high inventories, rough diamonds also face demand weakness due to lower demand from India and China (FXI)(MCHI), high inventory, and very low trade manufacturing margins. So, it’s important to look at Rio’s approach to volume growth and the outlook for this division.\nStable mineral production\nRio Tinto operates through three diamond assets. They are Argyle, Diavik, and Murowa. Diamonds produced at Argyle were 47% higher YoY (year-over-year) in 2015 and 43% higher YoY at 13.5 million carats. This is due to the continued ramp-up of production from the underground mine.\nDiavik’s production, on the other hand, fell by 11% YoY in 2015 and 3% YoY in 4Q15. This was due to pauses in the processing plants and the absence of stockpiled ore. This was done mainly to align the production with current weak market demand.\nRio announced the sale of its interest in the Murowa mine on June 26, 2015. Uranium production in 2015 was 72% higher YoY. This mainly reflected the complete shutdown of processing facilities in the first half of 2014 due to the failure of a leach tank.\nAligning guidance with market demand RIO’s guidance of 21 million carats for diamonds implies a YoY growth rate of 21% in production for 2016. For titanium dioxide’s feedstock production, the management is also trying to align production with market demand. To achieve this goal, Rio has taken two furnaces at Sorel offline, and it’s going for temporary shutdowns at Havre-Saint-Pierre. The company has guided for an 8.2% fall YoY in production for 2016. Rio’s uranium production guidance for 2016 is between 5 million pounds and 6 million pounds.\nETFs that invest in these companies, like the SPDR S&P Global Natural Resources (GNR), provide diversified exposure to the metals and mining sector. When combined, BHP Billiton and Rio Tinto equal 6.7% of GNR’s assets.", "pred_label": "__label__POS", "pred_score_pos": 0.6249780654907227}
{"content": "Rootstock and seasonal variations affect anthocyanin accumulation and quality traits of ‘Kyoho’ grape berries in subtropical double cropping system Abstract\nThe double cropping system has been commercially adopted in subtropical viticulture regions. However, very limited information about rootstock and seasonal effects on berry quality traits are available for this unique production system. Developing ‘Kyoho’ berries from own-rooted vines and from vines on 5C and 1202C rootstocks were periodically sampled from veraison until harvest in two consecutive cropping cycles to document the potential seasonal influence on rootstock effects. Anthocyanin concentration in berry skin, total soluble solids content (TSS), and titratable acidity (TA) were analyzed. In both cropping cycles, own-rooted vines produced berries with the highest anthocyanin concentration while vines on 1202C produced berries with the lowest anthocyanin concentration among the three scion/rootstocks. Anthocyanin concentrations were not differentiated by the differential climate pattern between the summer and the winter cropping cycles. Berries of own-rooted ‘Kyoho’ and ‘Kyoho’/5C vines accumulated satisfactory and equal amount of TSS in both cropping cycles. 1202C rootstocks did not affect berry TSS in the summer cropping cycle but reduced TSS in the winter cropping cycle. Significant rootstock and seasonal effects on berry TA were detected. Own-rooted vines produced berries with the lowest TA while vines on 1202C produced berries with the highest TA among the three scion/rootstock combinations. TA of berries from the winter cropping cycle was significantly higher than that from the summer cropping cycle especially in ‘Kyoho’/1202C. Relationships between anthocyanins and TSS of developing berries after veraison properly fitted into a sigmoidal function regardless of rootstocks and cropping cycles. However, the duration of the initial lag phase, the onset and the trend of both quality triats in the increasing phase, and the presence and degree of the final lag phase in the relationship were all modulated by rootstocks and by seasonal variations.\nThe content of VITIS is published under a Creative Commons Attribution 4.0 license. Any user is free to share and adapt (remix, transform, build upon) the content as long as the original publication is attributed (authors, title, year, journal, issue, pages) and any changes to the original are clearly labeled. We do not prohibit or charge a fee for reuse of published content. The use of general descriptive names, trade names, trademarks, and so forth in any publication herein, even if not specifically indicated, does not imply that these names are not protected by the relevant laws and regulations. The submitting author agrees to these terms on behalf of all co-authors when submitting a manuscript. Please be aware that this license cannot be revoked. All authors retain the copyright on their work and are able to enter into separate, additional contractual arrangements.", "pred_label": "__label__POS", "pred_score_pos": 0.5614423751831055}
{"content": "CMBG is an experienced restructuring firm that helps companies experiencing financial hardship build creative strategies towards a path to recovery. Whether the answer is to restructure, close, or restart your business, the team at CMBG will thoughtfully work to identify your objectives and develop the right solution for your needs.\nWhile bankruptcy is one available tool, it isn't always the best option. Some alternatives include negotiating with creditors directly to reduce liabilities, corporate reorganization, debt consolidation, exploring merger and acquisition opportunities, or the California state alternative to bankruptcy, an Assignment of the Benefit of Creditors (ABC).\nRegardless of the option that fits you best, finding an experienced professional to lead you through the process is your first step.\nWe offer a Client-based approach... Services ABC Bankruptcy Liquidations Negotiations Receiverships Restructuring Strategic Planning\nThe uncertainty of not knowing how to move forward with a company in distress can be paralyzing. That is why finding professionals who have the experience to strategize and provide options is key to successfully navigating the tempestuous seas of insolvency.\n- James K. Baer, Founder", "pred_label": "__label__POS", "pred_score_pos": 0.8324872255325317}
{"content": "Summary\nStephan Seiler is an Associate Professor of Marketing at Imperial College. Professor Seiler received his PhD from the London School of Economics and was previously employed at Stanford and UCLA. His research focuses on consumer choice in various markets. He analyzes issues ranging from the choice of hospital for a bypass operation to the reaction of consumers to promotions of laundry detergent. He is particularly interested in understanding consumer search behavior, such as how informed consumers are about prices or other product characteristics when making a purchase decision. Another strand of his research analyzes the production and impact of user-generated content on platforms such as Wikipedia and Twitter.\nPublications Journals\nSeiler S, Tuchman A, Yao S, 2020, EXPRESS: the impact of soda taxes: pass-through, tax avoidance, and nutritional effects,\nJournal of Marketing Research, ISSN:0022-2437\net al., 2018, Advancing Non-compensatory Choice Models in Marketing,\nCustomer Needs and Solutions, Vol:5, ISSN:2196-291X, Pages:82-92\nSeiler S, Yao S, Wang W, 2017, Does Online Word of Mouth Increase Demand? (And How?) Evidence from a Natural Experiment,\nMarketing Science, Vol:36, ISSN:0732-2399, Pages:838-861\nSeiler S, Yao S, 2017, The impact of advertising along the conversion funnel,\nQuantitative Marketing and Economics, Vol:15, ISSN:1570-7156, Pages:241-278\net al., 2017, Multi-Category Competition and Market Power: A Model of Supermarket Pricing,\nAmerican Economic Review, Vol:107, ISSN:0002-8282, Pages:2308-2351", "pred_label": "__label__POS", "pred_score_pos": 0.7147181034088135}
{"content": "Securing land tenure is often a necessary but rarely sufficient requirement for long-term sustainability of agricultural production and rural communities. To maintain and increase its value, land must be managed within its sustainable potential. This paper reviews the challenges of determining the agricultural potential of specific land types (soil+topography+climate), and accessing relevant information and knowledge necessary for management. It describes the global Land-Potential Knowledge System (LandPKS), which is addressing these challenges described by using information on soil, topography, and climate to provide site-specific knowledge and information through mobile apps and cloud-computing. This system can also be used to more equitably allocate land based on its sustainable production potential. The free apps are currently being used to inventory and monitor the impacts of several rangeland restoration and management projects. By the end of 2017 they will provide users with relative potential production and soil erosion risk under several management scenarios, including annual cropping. The system is completely open, and all data are available on a data portal and through Application Programming Interfaces (API) thus allowing links to other mobile and web-based services. User inputs are used to increase the precision of soil identification and subsequent management relevant information using a simple icon-based interface supported by short embedded video clips. Future versions will provide soil-specific management information from new (including user-generated) and existing knowledge bases.\nKey Words: cloud computing, mobile apps, open data, sustainable intensification, sustainable land management,", "pred_label": "__label__POS", "pred_score_pos": 0.5806748867034912}
{"content": "Faces and facets: The variability of emotion recognition in psychopathy reflects its affective and antisocial features. Igoumenou A., Harmer CJ., Yang M., Coid JW., Rogers RD.\nPsychopathy consists of a constellation of affective-interpersonal features including lack of empathy, callousness, manipulativeness and interpersonal charm, impulsiveness and irresponsibility. Despite its theoretical and predictive value in forensic contexts, the relationships between the psychometric dimensions of psychopathy, including its antisocial features, and the construct's neuropsychological characteristics remain uncertain. In this study, 685 personality-disordered prisoners with histories of serious violent or sexual offenses were assessed for psychopathy before completing a computerized and well-validated assessment of the ability to recognize emotional expressions in the face. Prisoners with more of the affective features of psychopathy, and prisoners with more of its antisocial manifestations, showed relatively poor recognition accuracy of fearfulness and disgust. These relationships were independent and modest but were still evident following correction for demographic features (e.g., ethnicity and socioeconomic status), mental illness (e.g., substance and alcohol misuse), personality disorders (other than antisocial personality disorder) and treatment status. By contrast, the associations between these dimensions of psychopathy and emotion recognition were diminished by controlling for cognitive ability. These findings demonstrate that variability in the ability of high-risk personality-disordered prisoners to recognize emotional expressions in the face-in particular, fear and disgust-reflects both the affective and antisocial aspects of psychopathy, and is moderated by cognitive ability. (PsycINFO Database Record", "pred_label": "__label__POS", "pred_score_pos": 0.996256947517395}
{"content": "A thorough understanding of siting issues is essential for the success of any construction project: offshore geotechnical surveys in deep water, near shore and at landfalls, as well as onshore investigations, provide companies with reliable basic data for designs and support with geotechnical engineering and monitoring services.\nInvestigations for marine constructions include:\nGeotechnical investigations from dedicated drilling vessels or jack-up platforms include:\nWe have been continuously active in geotechnical offshore surveys for decades, with a significant track record in shallow to deep water, mainly for oil & gas projects.\nWe use our dedicated containerized field laboratories for testing on board of vessels or in remote field locations. Standard and advanced testing, as well as sedimentology core logging, are carried out in our laboratory in Genoa, Italy.\nThis site or the third party tools it uses, make use of cookies needed to function and useful for the purposes indicated in the cookie policy. To learn more or deny consent, consult the cookie policy. By closing this banner, scrolling this page, clicking on a link or continuing to browse in another way, you accept the use of cookies.", "pred_label": "__label__POS", "pred_score_pos": 0.5751737356185913}
{"content": "We are excited to welcome you back! We are putting safety protocols in place as part of our program, so your next visit is safe and comfortable.\nAs many of you may have seen, the World Health Organization (WHO) recently released COVID-19 considerations suggesting that patients delay visiting the dentist for routine procedures.\nThe Canadian Dental Association (CDA) clarified that the WHO considerations\n\"are not relevant for the current status in Canada since there is not wide-spread community transmission of COVID-19 in our country.\"\nKeeping our patients safe is our top priority, and we remain committed to following strict guidelines and safety protocols.", "pred_label": "__label__POS", "pred_score_pos": 0.51475590467453}
{"content": "Austria's status of neutrality contended with crises almost immediately after its founding along with the 1955 State Treaty. First, during the Soviet invasion of Hungary in October 1956, Austrian neutrality faced the threat of conflict when Soviet-Hungarian clashes spilled over into Austria. Then, in July 1958, Austrian neutrality contended with more benign, but nonetheless disturbing, provocations from the Cold War's Western superpower, the United States. As U.S. military planes transited Austria in broad daylight on their way to Lebanon, the cozy, covert Austro-American relationship became all too overt. Although many Austrians believed neutrality would end foreign (particularly Soviet) domination and would ensure an ultimate withdrawal from global upheavals, these events showed that neutrality by itself could not remove the strategic implications inherent in Austria's position in Cold War Central Europe. Indeed, partisan strategic calculations in both East and West had played a significant role in creating Austrian neutrality. As a result, preserving both Austria's neutrality and its links to the West required delicate maneuvering by a small, poorly defended country amid Cold War crosscurrents of Eastern threats and Western sympathies. Already in its early years, Austrian neutrality proved to be less of the holiday from history that many Austrians expected during the festive mood of May 1955.", "pred_label": "__label__POS", "pred_score_pos": 0.6902576684951782}
{"content": "Jonathan Ashworth\n\"A thorough and comprehensive analysis of the history and effects of quantitative easing.\" –\nC. A. E. Goodhart, from the Foreword\nBefore the Great Financial Crisis of 2008–09, significant reductions in official interest rates typically proved sufficient to generate sustainable economic recoveries from downturns. However, with economies and financial markets in freefall during the crisis despite a cut in interest rates to effectively zero, policymakers in some advanced economies launched a major new tool called quantitative easing (QE). This involved central banks purchasing huge amounts of financial assets.\nThis book offers a thorough and perspicacious analysis of QE, which has become a recovery method of last resort. Whilst it was successful in averting another Great Depression and stimulating growth, it remains controversial and continues to promote widespread debate in economics, financial, and political-economy circles. This book is essential reading for anyone wishing to understand central banking in the national economy.\nForeword by C. A. E. Goodhart 1. Monetary policymaking since the end of Bretton Woods 2. Key monetary policy trends and events before the Great Financial Crisis 3. The Great Financial Crisis and quantitative easing 4. How quantitative easing works 5. Measuring the effectiveness and impact of quantitative easing 6. International spillovers of quantitative easing 7. Criticisms and negative externalities of quantitative easing 8. Exiting quantitative easing and policies for the next slowdown\nJonathan Ashworth is an independent economist. He has worked as an economist at Morgan Stanley and Barclays Wealth and his work has been widely cited in the media including The Economist, The Financial Times and The Wall Street Journal. He has also worked as an economist in the productivity and structural reform team at HM Treasury, where he did work on the famous \"Five Tests\" for whether Britain should join the euro.", "pred_label": "__label__POS", "pred_score_pos": 0.9238572716712952}
{"content": "Depression is very real. It can cause us to feel isolated, alone, and hopeless…like everything around us is falling apart.\nSatan uses depression to steal a person’s spiritual power and freedom—he seeks to fill our minds with darkness and gloom and bring us down emotionally. However, God wants to help us live free from depression. He wants to fill us with His joy, hope and expectation of good things for our lives.\nDon’t believe the enemy’s lies about your situation. Resist him. He is no match for the God of life, who lives in you (Colossians 1:27), has a purpose good things planned for your life (Ephesians 2:10), and will rescue you when you call (Psalm 91:15, Psalm 50:15).", "pred_label": "__label__POS", "pred_score_pos": 0.5480650067329407}
{"content": "Conductive hydrogel composites with autonomous self-healing properties† Abstract\nConventional conductive hydrogels usually lack self-healing properties, but might be favorable for smart electronic applications. Therefore, we present the fabrication of conductive self-healing hydrogels that merge the merits of electrical conductivity and self-healing properties. The conductive self-healing hydrogel composite was prepared by using single-walled carbon nanotubes (SWCNTs), poly(vinyl alcohol) (PVA), and a poly(\nN, N-dimethyl acrylamide) copolymer derivative modified with pyrene and borate functional moieties. While the tethered pyrene groups of the copolymer facilitated an even dispersion of the conductive components, i.e., SWCNTs, in aqueous solution via π–π stacking, the hydrogel system was formed via covalent dynamic cross-linking through tetrahedral borate ion interaction with the –OH group of PVA. The hydrogel composites exhibited bulk conductivity (1.27 S m −1 with 8 mg mL −1 SWCNTs) with a fast and autonomous self-healing ability that restored 95% of the original conductivity within 10 s under ambient conditions. Accordingly, due to their outstanding properties, we postulate that these composites may have potential in biomedical applications, such as tissue engineering, wound healing or electronic skins.", "pred_label": "__label__POS", "pred_score_pos": 0.8174997568130493}
{"content": "A Ritual of Habits The meanings associated with food often originate with the upper classes who control production before these meanings are passed to the farmers and laborers who grow and produce these foods. Distribution and access to food is not only a matter of satisfying physical needs, but also a display of power and control — especially for goods like sugar that were once considered luxuries. Historically, sugar has been treated as a source of power, health, and strength — much like spices, medicine, and precious stones.\nMy family embraces sugar as part of our lifestyle, and this significance follows from our family history. For us, sugar remains luxurious, exotic, and integral to many ceremonies despite its widespread availability. Sugar still symbolizes our relationship to Taiwan as a colonized space.\nI spent two years cataloging images of everything sweet in my diet using a 3D scanning technique called photogrammetry. Constructing a 3D model through photogrammetry requires images of an object to be captured from all angles, disassembled into parts, then stitched together in digital form. I found that this repetitive, surgical process turns photogrammetry into a ritual, transcending the mindless and impulsive consumption of sugar itself and reconstructing these objects as something new.\nThe virtual component allows one to witness the ritualistic process of capturing 3D images from all angles. In the final scene, the viewer is transported to a space where the entire collection unfolds. The objects are displayed on pedestals and mounted on walls as trophies, morphing as the viewer shifts their gaze. At a certain point the viewer loses direct control over what is happening in their field of vision, they are placed inside and outside of these objects, both consuming and being consumed.\nSound design by Matthew Dougherty. Digital Archive 3D Printed Sculptures Installation Chicago Tribune The Verge\n3D Printed Sculptures\nInstallation\nChicago Tribune\nThe Verge\nHyperallergic POV Spark‘s PUBLIC UPDATE (American Documentory)\n360 Rendering", "pred_label": "__label__POS", "pred_score_pos": 0.7917668223381042}
{"content": "In the point-to-point transport sector, ride sharing services like UberX, GoCar and GoCatch have disrupted the industry. And government policy has been struggling to keep up, in the context of a highly regulated taxi industry and their very vocal complaints. The disruption is not over yet!\nWhat could this mean for the future of public transport? Autonomous Transit\nIn February 2016, the Western Australian Royal Automobile Club announced a trial of autonomous, driverless and fully electric series vehicle to commence in 2016 – using the French NAVYA ARMA shuttle bus – which can transport up to 15 passengers and safely drive up to 45 km/h.\nThis vehicle aims to complement the existing transport system over distances which are too short to travel by car but too far to walk.\nMaybe a peek into the future? Mobility as a Service\nMobility as a service (MaaS) is also building up a head of steam. MaaS combines services from public and private transport providers, across multiple modes, through a unified gateway that manages the trip, which users can pay for with a single account.\nTwenty European organisations joined forces to establish the first MaaS Alliance. Also in Europe, MaaS Finland offers a choice of simple, monthly mobility packages, including everything from public transport to taxis and rental cars.\nThese services are an obvious extension of the ride sharing services – what are the implications for government? Demand Responsive Transit\nDemand Responsive Transit (DRT) provide flexible point to point shared ride passenger services, with flexible routing and scheduling of smaller passenger vehicles, responding to passengers needs.\nLogically these services provide a niche service on a continuum of cost and level of service, between taxi and a scheduled bus services. We cannot afford as a community to fund passenger services to cover all urban areas. See previous article: Bus network design: CSO or ROI?\nDRT services are particularly suited to low density or low demand urban areas, especially in regional areas where a traditional scheduled bus service is not viable.\nWhat do these developments mean for future public transport?\nWhat are the implications for public transport operations?", "pred_label": "__label__POS", "pred_score_pos": 0.8156045079231262}
{"content": "Return Predictability in Federal Funds Futures: Is it there?\nAuthors: Sigurd Anders Muus Steffensen (Aarhus University)\nTitle: Return Predictability in Federal Funds Futures: Is it there?\nAbstract: This paper re-examines the performance of the variables suggested to be good predictors of excess returns in federal funds futures. I show that they are unstable, and do not consistently outperform the expectations hypothesis (EH) benchmark when evaluated out-of-sample. To accommodate this instability, I apply forecasting methods that combine the information of all predictors at once, and find that this produces statistically significant out-of-sample R2 statistics. Further, I assess the economic value of this forecasting ability in terms of mean-variance profitability and risk-adjusted monetary policy forecast. Results from both analyses are favorable to the EH, suggesting that predictable deviations from the EH are not economically significant in federal funds futures, and that the contracts do not require adjustment for time-varying excess returns when they are used as measures of monetary policy expectations.", "pred_label": "__label__POS", "pred_score_pos": 0.9075392484664917}
{"content": "hide\nFree keywords: -\nAbstract: Perceptual bistability arises when two conflicting interpretations of an ambiguous stimulus or images in binocular rivalry (BR) compete for perceptual dominance. From a computational point of view, competition models based on cross-inhibition and adaptation have shown that noise is a crucial force for rivalry, and operates in balance with adaptation. In particular, noise-driven transitions and adaptation-driven oscillations define two dynamical regimes and the system explains the observed alternations in perception when it operates near their boundary. In order to gain insights into the microcircuit dynamics mediating spontaneous perceptual alternations, we used a reduced recurrent attractor-based biophysically realistic spiking network, well known for working memory, attention, and decision making, where a spike-frequency adaptation mechanism is implemented to account for perceptual bistability. We thus derived a consistently reduced four-variable population rate model using mean-field techniques, and we tested it on BR data collected from human subjects. Our model accounts for experimental data parameters such as mean time dominance, coefficient of variation, and gamma distribution fit. In addition, we show that our model operates near the bifurcation that separates the noise-driven transitions regime from the adaptation-driven oscillations regime, and agrees with Levelt’s second revised and fourth propositions. These results demonstrate for the first time that a consistent reduction of a biophysically realistic spiking network of leaky integrate-and-fire neurons with spike-frequency adaptation could account for BR. Moreover, we demonstrate that BR can be explained only through the dynamics of competing neuronal pools, without taking into account the adaptation of inhibitory interneurons. However, the adaptation of interneurons affects the optimal parametric space of the system by decreasing the overall adaptation necessary for the bifurcation to occur, and introduces oscillations in the spontaneous state.", "pred_label": "__label__POS", "pred_score_pos": 0.8078761696815491}
{"content": "You are here Fiji\nThis summary outlines how humanitarian actors can support locally-led responses to disasters in the Pacific. It summarises lessons from previous responses, findings from localization research in the Pacific, and emerging thinking about localization in the\nUnseen, Unsafe: The underinvestment in ending violence against children in the Pacific and Timor-Leste\nUnseen, Unsafe reveals the alarming scale of violence being perpetrated against children in the Pacific and Timor-Leste, and the critically low amount of funding being invested to address it. Produced by Save the Children in collaboration with Child Fund,\nIn 2018 and 2019, PIANGO and Humanitarian Advisory Group collaborated to design and undertake a localization process in four Pacific countries: Vanuatu, Tonga, Fiji and the Solomon Islands. Pacific actors began by discussing and prioritizing areas of meas\nFiji has experienced several large-scale cyclones during the last years, with earthquakes and floodings also being common. As a regional hub for the Pacific, many international and regional organizations are based there, alongside a large presence of civi\nThese flashcards are meant for facilitators and children in Disaster Risk Reduction clubs. The cards introduce eight key hazards in Fiji. They are to be utilized as large picture printouts, with simple information on the backside that the facilitator can\nThe past decade has seen an increased focus within research and practice on placing children at the centre of efforts to reduce disaster risk, including those risks associated with climate change. An increasing body of research demonstrates that children\nIggyVola is a resource workbook for children on disaster risk reduction and climate change. It has a child-friendly narrative, characters with stories, and suggestions for activities. It is particularly suitable for extra-curricular Disaster Risk Reductio\nIntroductory Research on the Feasibility of Cash and Voucher Assistance in Rural Fiji: Research report\nThis research report examines the feasibility of using Cash and Voucher Assistance in responding to disasters in Fiji. The study is part of the work of the Pacific Cash Preparedness Partnership, which is focused on conducting feasibility studies across Va\nChild Protection in Emergencies Professional Development Programme, Asia Pacific 3rd cycle: Residential Report\nThe Residential phase of the Child Protection in Emergencies Professional Development Programme (CPiE PDP) is a two-week training during which the participants develop knowledge and skills to design and implement high-quality Child Protection in Emergenci\nThe global humanitarian sector has recently begun to develop ways to measure progress on localization efforts. This has also been a key issue for humanitarian actors in the Pacific region. In June 2018, the Pacific Islands Association of Non-Governmental\nPost-Disaster Educational Continuity in Fiji and the Impact of Disaster Risk Reduction and Education in Emergencies Programming\nEducation in Emergencies (EiE) is defined as “the provision of uninterrupted, high-quality learning opportunities for children affected by humanitarian crisis”. The Comprehensive School Safety (CSS) Framework has emerged more recently and focuses also on\nKey Messages for Disaster Risk Reduction and Resilience in Fiji: A guide for public education & awareness\nThis DRR guide for public education provides simple and accurate advice on what to do in case of various emergencies (hazards: drought, earthquake, floods, pandemic, tropical cyclone, wildfires, infestation, landslide & debris flow, tsunami, storm surge &", "pred_label": "__label__POS", "pred_score_pos": 0.5361643433570862}
{"content": "Abstract\nThe acoustic startle response in rats shows both short-term habituation, which recovers in seconds or minutes, and long-term habituation, which is effectively permanent. Lesions of the cerebellar vermis significantly attenuated long-term habituation without affecting the short-term process or altering initial response levels. In this response system the cerebellar vermis is part of an essential circuit for long-term habituation.", "pred_label": "__label__POS", "pred_score_pos": 0.9999545216560364}
{"content": "Viavi Solutions has announced the availability of Observer 18, delivering end-user experience scoring, streamlined workflows and high-fidelity forensics, powered by the fastest stream-to-disk platform available in the market. As employees and users increasingly work away from the office, school campus, or hospital, NetOps and SecOps teams face twin challenges: optimise performance of the network even when that network can physically be located anywhere, while protecting against security threats, especially when those threats are taking advantage of atypical operating procedures.\nVIAVI has developed this release of Observer to address these requirements, combining streamlined workflows and ease of use with technical efficiencies and cost savings, for faster resolution of issues across teams – wherever they virtually are across cities or countries. Observer 18 includes a range of features to support performance and security use cases, such as identifying users by name, determining where they connect, or automatically identifying when a host or service is communicating abnormally.\nKey updates to the Observer Platform include: Custom-designed GigaStor Generation 4 hardware platform with up to 60 Gbps capture rate and accelerated analytics, providing the industry’s fastest access to stored packet data and analysis, as validated by the Tolly Group. Unique End-User Experience scoring, with automated domain isolation capabilities, turning mountains of raw data into clear, concise answers and next steps. Seamless unification of flow and packet data, enabling users to efficiently move from holistic site, application, or threat views to in-depth forensic analysis. Improvements in hardware design driving operational efficiency, from easier installation due to size reduction of 67 per cent compared to the previous generation, to lower power consumption thereby reducing energy costs.\nCommenting on the development, Charles Thompson, senior director, enterprise and cloud, VIAVI, said, “As enterprise workforces and users become more distributed, and rely on applications located in multiple clouds, the resulting any-to-any networking model is susceptible to performance and security challenges. Observer 18 empowers stakeholders from business leaders to level 3 support with customisable, streamlined workflows and intuitive visualisations, based on the most complete data set available. When they take control, they can guarantee that both work and learning can happen, wherever it needs to happen.”\nFurther, Kevin Tolly, Founder of The Tolly Group, added, “Whether ensuring optimal end user experience or addressing security threats, maintaining IT service health begins with complete visibility into network traffic. The Tolly Group completed testing of the Observer GigaStor Gen4 product family. Models tested were rated at 20, 40, and 60 Gbps. Results met or exceeded the performance claims of VIAVI, including their fastest model which showed sustained packet capture of 60.5 Gbps with real-world enterprise packet size of approximately 400 bytes.”", "pred_label": "__label__POS", "pred_score_pos": 0.9161780476570129}
{"content": "Binhi is a Filipino word for “seed.” This reflects the goal of BINHI English Literacy Foundation of planting seeds of empowerment among Filipino children through its DepEd Adopt-a-School accredited literacy program.\nOne in every ten Filipinos aged 6 to 24 is an out-of-school youth and the leading reasons for such are family matters, lack of personal interest, and financial concerns. It is very likely for this number to rise due to the challenges brought about by COVID causing around 4 million learners not to enroll for the coming school year, according to DepEd.\nLet us help in motivating the youth to stay in school and in building their confidence to dream big. It is through youth empowerment that we uphold the future of our nation by teaching them to read and write today. This is emphasized in BINHI’s belief that “Today they read, tomorrow they lead.”\nYOU CAN STILL VOLUNTEER BY SHARING YOUR TREASURE to help Filipino students stay in school and foster learning. Treasure Volunteering allows you to donate either via Paypal or with your credit/debit card. Let us be instruments in making the children feel the spirit of love and giving during Christmas amid the pandemic.", "pred_label": "__label__POS", "pred_score_pos": 0.9873084425926208}
{"content": "Have you ever read a book that just lit up your brain? And when I say \"lit\", I mean it made all sorts of light-bulbs go off. I'm currently reading one of those books.\nAt the beginning of the year, I started reading\nThe Book of Awakening\nNow, since I'm a sucker for a good a-ha moment, particularly ones that are shareable, I thought it would be fun to share some of the love with you.\nThis is a snippet from the passage titled \"Being Kind-I\"...\n\"The great and fierce mystic William Blake said, there is no greater act than putting another before you. This speaks to a selfless giving that seems to be at the base of meaningful love. Yet having struggled for a lifetime with letting the needs of others define me, I've come to understand that without the healthiest form of self-love - without honoring the essence of life that this thing self carries, the way a pod carries a seed - putting another before you can result in damaging self-sacrifice and endless co-dependence.\"\nI've lived up close and personal to\nco-dependence . Been there, done that. Have the t-shirt and the tiara. So, this passage reminded me of the many times I used to confuse people-pleasing and peace-keeping with being kind. And I don't think I need to tell you....there's a HUGE difference.\nFor example, stuffing my feelings to keep the peace all because I didn't want to trouble someone else or run the risk of ticking them off. (I still fall into the old habit of saying, \"I'm fine.\" when I'm really not.) Stuffing wasn't kind; it created all sorts of internal chaos.\nOR\nDoing/Saying things that didn't fit with me to please someone else. That wasn't kind; that got me lost and there's nothing kind about losing your identity. Not to mention, I was lying and lying isn't kind.\nENTER A-HA MOMENTS, STAGE LEFT\nA-ha moment #1: The most unkind thing we can ever do to ourselves and others is to not be ourselves. Genuine, heartfelt kindness comes from being who we are.\nA-ha moment #2: True kindness doesn't hurt and it sure as heck doesn't cost us our identity or our well-being. EVER\nSo, I have to ask, do you find yourself being authentically kind? Or do you find that you're being kind at the cost of yourself, your feelings, and/or your well-being?\nDetails", "pred_label": "__label__POS", "pred_score_pos": 0.7222797870635986}
{"content": "Wazzup Pilipinas!\nThe Department of Energy – Electric Power Industry Management Bureau (DOE-EPIMB) conducted a public consultation on the proposed amendments of the Wholesale Electricity Spot Market (WESM) Rules at Parklane Hotel, Cebu, on 24 January 2019. The event was attended by representatives from local distribution utilities (DUs), power generating facilities, local government units, the academe, and members of the media.\nThe proposed amendments submitted by the Philippine Electricity Market Corporation (PEMC) to the DOE in September 2018 aims to strengthen current rules on market surveillance, enforcement, compliance and penalties.\nEnergy Secretary Alfonso G. Cusi said, “We need to empower our consumers on their right to be informed on how and where their electricity is being sourced. Their ‘firsthand involvement’ will benefit the entire energy sector as we hear their inputs on the significant improvements of market operation services and competitive pricing.”\nThe recommended changes seek to strengthen the roles and functions of those involved in enforcement and compliance processes; harmonize said processes with the enhanced WESM design; switch from an hourly to a five-minute trading interval; establish procedures and obligations on the issuance of notices for market rules breaches; determine appropriate violation penatlies; penalty remedies; and the utilization of penalty proceeds, among others. The revision of Market Manuals which serves as guidelines for electricity trading were also presented during the event.\n“Greater transparency on electricity market processes results to a faster determination on what is best for our consumers,” Sec. Cusi added.\nThe DOE is on its 3rd leg of public consultations for the amendment of the WESM Rules, with previous public consultations held on 15 January 2019 for Mindanao and 17 January 2018 for Luzon.", "pred_label": "__label__POS", "pred_score_pos": 0.8690125942230225}
{"content": "The Ministry ofLabour and Employment has, with view to the changing industrial and economicscenario of the nation, proposed to amend theEmployees’ Provident Funds and Miscellaneous Provisions Act, 1952 vide theEmployees’ Provident Funds and Miscellaneous Provisions (Amendment) Bill, 2019(“\nBill”) on August 23, 2019. TheBill is open for suggestions and objections from the concerned stakeholders andother members of the public till September 22, 2019. Key Highlights\nIn this Article we shall discuss the salient features of the Bill as follows:\nWages\nBill has removed the basic wage as existed in the Act and has replaced it with “Wages” which is in conformity with the definition of “Wages” as brought in by the Code on Wages, 2019, as notified on August 8, 2019. While earlier, the basis for computation of provident fund was basic wage, it has now become computational to wage which is inclusive of basic pay, dearness allowance and retaining allowance. The amendment specifically excludes various specific payments made by the employer to the employee such as any bonus, the value of house accommodation, contribution by an employer to pension or provident fun, conveyance allowance, house rent allowance, overtime allowance, retrenchment allowance etc. However, the Bill specifically states that if all such excluded payments exceed 50% or such other percent of all remuneration calculated, then such exceeded payment shall be deemed as remuneration and shall be made part of “Wages”.\nContribution by Employee\nThe Bill has proposed flexibility regarding the rate of contribution for various class of employees. Central Government has been given the power to determine such percentage and the period for which such rates shall be applicable. Further, the Bill clarifies that the employer shall not be under an obligation to pay any contribution over and above his contribution of 12%. This modification and flexibility in rates come in pursuance to the announcement made in the annual budget of year 2015-2016 wherein it was stated that Employees’ Provident Funds contribution shall be made optional for employees below a certain threshold of monthly income. While the idea took 3 years to come on papers, it is a positive change to ensure no additional burden on low income earner is brought in.\nLimitation to inquiries\nSection 7A of the Act deals with the initiation of inquiry regarding the applicability of the Act and determining the amount due from any employer under any provision of the Act. The Act provided no limitation to the initiation of inquiries under Section 7A of the Act, thereby allowing the competent authorities to initiate inquiries for any period of time, be it from the date of the commencement of such establishment. Such an ambiguous and open-ended power to the authorities was prone to misuse. Therefore, the Bill now amends Section 7A wherein a limitation period of five years has been brought in to initiate inquiry from the date the alleged amount is considered to be due. Further, the Bill also states that the inquiry should be held on a day to day basis and should be concluded within a period of two years, as far as practicable. In the event the inquiry is not concluded within two years, the authority must record the reason for such delay.\nPrioritizing payment of Provident Fund\nBill clearly emphasizes vide Section 11 that any amount due for the provident fund shall be considered as the first charge on the assets of the establishment and it shall be paid in priority to all debts. Therefore, the Bill proposes that if an establishment has various debts and the creditors and approached competent authorities under the Insolvency and Bankruptcy Code, 2016, it must be ensured that the amount due under this Act is prioritized and paid before any other dues.\nFines\nBill proposes to enhance the penalties as are levied under the Act. For instance, failure on behalf of an employer to contribute towards PF is punishable with imprisonment up to 3 years and fine of INR 50,000 which at present is punishable at INR 5000 in the Act. Therefore, one can note that the penalties have enhanced ten times to what existed.\nCompounding of certain offences\nBill introduces a Clause 14AD wherein it states that all offences other than those specified in Section 14(1), (1A) and (1B) can be compounded by paying such compounding rates without the need to undergo a trial. This insertion, therefore, reduces the burden on the officers to conduct a trial for minor offences.\nConclusion\nThe Bill proposes to make various positive amendments in the Act, such as the introduction of the limitation period for initiation of inquiry. Post Supreme Court observation on basic wage, in the case of\nRegional Provident Fund Commissioner (II) West Bengal vs Vivekananda Vidyamandir and Others[1] (“ Judgement”), establishments witnessed various random inquiries being initiated by the authorities, to check compliance with the law. The case law fails to state the time period of applicability of the Judgement and whether the same can be made retrospectively applicable and thereby penalized by the authorities for non-compliance. Consequently, a notice was thereby issued by the Employees’ Provident Fund Organisation on August 28, 2019[2] (“ Circular”) wherein the authorities namely Additional Central Provident Fund Commissioners and Regional Provident Fund Commissioner were directed to refrain from initiating roving inquiries into the wage structure of the complying establishments on the presumption that certain allowances being in the nature of basic wages might not have been treated as part of pay for employee provident fund contribution. Such rogue issues were being initiated on the basis of the Judgement. The Circular stated that any inspection/investigation into the wage structure of the establishments shall be made only if there exists a prima facie evidence of illegal intention to avoid Employees’ Provident Funds liability by arbitrary bifurcation of wages and upon obtaining permission from CAIU. Further, the Circular also stated that no coercive action shall be taken for the recovery of dues till disposal of review petition as pending before the Hon’ble Supreme Court. However, the review petition in the matter has been dismissed by the Hon’ble Supreme Court on not finding any merit in the case to entertain the same. Therefore, the establishments are now left to the mercy of the Circular and the Bill to come into effect at the earliest, to understand the impact and liability of the Judgement on them and avoid arbitrary harassment by the authorities vide arbitrary inquiries.", "pred_label": "__label__POS", "pred_score_pos": 0.6085406541824341}
{"content": "Nobody knows funds like we do\nWhether it is pioneering new fund structures or developing innovative solutions to accommodate tax and regulatory change, the international funds team is part of the DNA of the investment funds industry.\nAs advisors to a greater variety of global funds than any other law firm, we know international funds inside out. We combine that market experience with in-depth tax and regulatory knowledge to give you practical, cost-effective legal advice that you can implement quickly.\nServing a financial hub\nSingapore is a key financial centre and a hub for fund managers and financial services firms. And the surge of capital in and through Asia has created a significant demand for high-quality legal services.\nOur Singapore practice provides multinational clients with top-tier international legal expertise for cross-border and international funds work in Southeast Asia. It also supports Singapore-based and international clients in their investments around the region including into China.\nWith a top-tier regional funds practice to build on, our Singapore practice is focussed on private equity, real estate and infrastructure funds work, complimented by strong regional mergers and acquisitions (M&A) expertise across those sectors.\nThe areas of international funds law we advise on include:\nPrivate equity and other private investment funds Real estate funds and Real estate investment trusts (REITs) Infrastructure and energy funds China related / RMB funds Investments and co-investments (both fund and direct) Secondary transactions Mergers & acquisitions, joint ventures and spin-offs.\nClients benefitting from our advice include:\nMacquarie, who we advised on several large infrastructure fundraisings for India, China and the Philippines; Equis Asia, who we assisted with raising of their first infrastructure fund; AMP, who we advised on several fundraisings for India and China; Ascendas, who we advised on the Australian aspects of its Ascendas Hospitality Trust listing; Major Singapore-based investors, who we advised on fund investments and co-investments; Global real estate and infrastructure managers, who we advised on cross-border investments around Asia Pacific; and A major investment bank, who we advised on establishing its US$1 billion infrastructure fund covering South Asia, India and Africa. \"The key strengths are their knowledge of the funds industry and their proactivity, responsiveness and business-friendly working attitude. You can be sure they are willing to go the extra mile to help you.\"\nChambers", "pred_label": "__label__POS", "pred_score_pos": 0.5261284112930298}
{"content": "This study presents a novel and rapid method to identify chemical markers for the quality control of Radix Aconiti Preparata, a world widely used traditional herbal medicine. In the method, the samples with a fast extraction procedure were analyzed using direct analysis in real time mass spectrometry (DART MS) combined with multivariate data analysis. At present, the quality assessment approach of Radix Aconiti Preparata was based on the two processing methods recorded in Chinese Pharmacopoeia for the purpose of reducing the toxicity of Radix Aconiti and ensuring its clinical therapeutic efficacy. In order to ensure the safety and effectivity in clinical use, th...", "pred_label": "__label__POS", "pred_score_pos": 0.702414870262146}
{"content": "MEDIA RELEASE\nThe Kohala Center today launched a series of online surveys aimed at soliciting input and feedback from various sectors of Hawai‘i’s organic food industry. The surveys are accessible online at www.laulimacenter.org/organic_… through Friday, August 2.\nThe surveys are part of an initiative to determine the feasibility and potential roles of one or more organizations or agencies that would effectively support the growth and vitality of Hawai‘i’s organic industry. The initiative is supported by a grant from the Hawai‘i Department of Agriculture.\nFarmers, producers, distributors, retailers, consumers, and agricultural professionals are encouraged to participate in one or more of the surveys. Participation is voluntary and anonymous. Data collected from the surveys will influence the development of solutions and recommendations to strengthen Hawai‘i’s organic industry.\nA nine-member advisory group comprised of organic farmers, producers, retailers, and agricultural professionals from around the state was convened in February to determine the primary barriers affecting the growth and sustainability of Hawai‘i’s organic industry.\nRepresentatives from local processors, distributors, retailers, certifiers, and the state legislature have also provided input to the group’s work. Based on the issues, barriers, and potential solutions defined by the advisory group, surveys were developed to gain insights and data from a broader range of industry constituents statewide.\n“Organic agricultural producers operating in Hawai‘i currently don’t have a central place where they can obtain information on critical issues such as infrastructure, processing, marketing, certification, and business development,” Melanie Bondera, Rural Cooperative Development Specialist for the Laulima Center, a program of The Kohala Center, said.\n“There are many entities in the state providing specific services, but no central educational or advocacy group. Our research seeks to determine how existing entities can support organics in Hawai‘i, and how the local industry can overcome the barriers that are affecting farming operations, production, distribution, quality, and costs.”\nSurvey data will be analyzed and integrated with the advisory group’s research to develop actionable solutions and recommendations to the Hawai‘i Department of Agriculture, as well as provide input on a legislative agenda for the industry in 2014. The advisory group will conduct an open meeting on Hawai‘i Island in late October, at which the group’s findings and preliminary recommendations will be presented to the public for feedback and further input.\nLearn more:\nThe Kohala Center ( www.kohalacenter.org ) is an independent, community-based center for research, education, and conservation. The center was established in direct response to the request of island residents to create greater educational and employment opportunities by enhancing—and celebrating—Hawai‘i’s spectacular natural and cultural landscapes.", "pred_label": "__label__POS", "pred_score_pos": 0.5670067667961121}
{"content": "‘Everyone's Child’: The Challenge of Judging Israeli Soldiers in the Shadow of the Conflict\nLaw, Culture and the Humanities (2019): https://doi.org/10.1177/1743872119852078\n47 Pages Posted: 2 Jul 2019 Last revised: 1 Sep 2020\nDate Written: May 1, 2019\nAbstract\nThis article addresses one of the most important and high-profile legal dramas in Israel in recent years: the trial of the soldier Elor Azaria, who shot and killed an incapacitated Palestinian assailant in the West Bank city of Hebron. It seeks to explain why the trial, which was compared to the O.J. Simpson trial in the USA, generated such unprecedented public controversy. I argue that rather than the ostensible central question of the soldier’s mens rea, the trial’s significance is in revealing competing images of the Israeli soldier upon his encounter with the law. Against the soldier’s legal categorization as a perpetrator (first accused, then convicted), the soldier’s supporters propagate an alternative image of the soldier as an innocent, victimized son, invoking the contested metaphor “everyone’s child.”\nThe article argues that this polarized view of the son-soldier nexus, foundational to the republican ethos of Jewish-Israeli society, affects the legal accountability of soldiers as official duty holders. I first consider David Grossman’s novel To the End of the Land (2008) as a text that imagines anew the hierarchies between the filial son and the national soldier, identifying two distinct yet intertwined processes of filialization and infantilization underlying this change. Based on the insights derived from the literary discourse, I move to offer a close reading of the court proceedings in the Azaria case, analyzing the law’s response to these conflicting images of the son-soldier. Keywords: law and literature, criminal law, military law, lethal use of force, Israeli Palestinian conflict", "pred_label": "__label__POS", "pred_score_pos": 0.5489645004272461}
{"content": "All recipes and tools on this website are intended for informational purposes only. We are not certified nutritionists and any nutritional information on blondelish.com should only be used as a general guideline.\nEven though we try our best to provide information as accurate as possible, we cannot guarantee that it will always be 100% accurate. The nutritional labels are a product of online calculators such as WP Recipe Maker and Spoonacular.\nNutrition information can vary for a recipe based on factors such as precision of measurements, brands, ingredient freshness, or the source of nutrition data.\nYou should not rely on this information as a substitute for, nor does it replace professional medical advice, diagnosis, or treatment. If you have any concerns or questions about your health, you should always consult with a physician or other health-care professional.\nStatements within this site have not been evaluated or approved by the Food and Drug Administration.\nThis website, blondelish.com, and its owners cannot be held responsible for any errors, omissions or inaccuracies published. This website, blondelish.com, and its owners disclaim all liability or loss in conjunction with any content provided here. This website, blondelish.com, and its owner disclaim any liability for products or services recommended on the site.\nThe reader assumes full responsibility for consulting a qualified health professional regarding health conditions or concerns before using the content on this site.\nTo obtain the most accurate representation of the nutritional information in any given recipe, you should calculate the nutritional information with the actual ingredients used in your recipe. You are ultimately responsible for all decisions pertaining to your health.\nThis website shall not be liable for adverse reactions or any other outcome resulting from the use of recipes or recommendations on the Website or actions you take as a result. Any action you take is strictly at your own risk.\nBy using blondelish.com and its content, you agree to these terms.", "pred_label": "__label__POS", "pred_score_pos": 0.6956884860992432}
{"content": "If you are facing the threat of deportation, you are likely overwhelmed and experiencing a number of emotional challenges. Many people feel stressed out about their ability to stay in the U.S. or even become depressed or angry. For those in long-term relationships, deportation is often especially concerning.\nWhether you have kids or a spouse and are worried about your ability to continue spending time with them or you are worried about what will happen to your relationship with someone you have spent many years with, it is critical to focus on your rights and understand your options.\nLooking at the consequences of deportation\nAccording to USA.Gov, people are deported from the U.S. for violating immigration laws. Sometimes, people have to appear in court during the deportation process. It is vital to go over every detail of the case with an experienced attorney and take the right approach.\nWhen a parent is deported, children often face immense emotional pain. Moreover, deportation can destroy strong relationships, including those which have lasted for many years. In recent months, removal is an incredibly difficult threat due to the complicated nature of international travel at this time.\nLooking at your options amid the threat of deportation\nSometimes, people facing deportation can stay in the U.S. by exploring their options and approaching their case from the right angle. Moreover, if your rights were violated while you were detained or during the removal process, you have the option to file a complaint. Some people are also able to appeal a deportation ruling successfully.\nFurthermore, some people can stay in the country by becoming a lawful permanent resident. It is crucial to speak to an immigration attorney about your case to ensure you can have the best defense to deportation and legally remain in the United States.", "pred_label": "__label__POS", "pred_score_pos": 0.6639118194580078}
{"content": "A recent study utilized search queries to determine the relationship of drug interactions between paroxetine and pravastatin. This type of inquiry could be expanded with current FDA monitoring of drug interactions and adverse effects.\nThanks for your submission, please share this app review\nSubscribe to our newsletter to receive updates on new medicalapps!\nJoin our mailing list to receive the latest news and updates from our team.", "pred_label": "__label__POS", "pred_score_pos": 0.6748974323272705}
{"content": "Most hospitals and wound healing centers require recertification. The recommendation is that our physicians recertify. However, there are physicians for whom wound care recertification is not needed. An alternate pathway to maintain certification is being offered. “Recredentialing” maintains the original certification date and allows physicians to maintain active certification with the Council for Medical Education and Testing.\nRecredentialing is not the same as recertification. Recertification provides an\nupdated certification date. Recredentialing maintains the original certification date. To clarify the difference, we are often requested to verify credentials by hospitals and wound healing centers. In these cases, when certification date is requested from a facility, the information that is given is dependent on the pathway chosen. We anticipate that the majority of our CMET physicians will recertify but this is an alternative to allow those doctors not requiring recertification to maintain their CMET “certified” status.", "pred_label": "__label__POS", "pred_score_pos": 0.9933401346206665}
{"content": "The European neurovascular device market will grow strongly through 2027, fueled by rapid expansion of the neurovascular thrombectomy device market and by the uptake of newer neurovascular intervention technologies.\nThis Medtech 360 Report provides high-level market metrics for neurovascular devices in Europe, including country-level data for major countries and aggregate data for the rest of Europe, across a 10-year period.\nNeurovascular Devices - Market Insights - Europe (Supplemental) Author(s): Shruthi Narendranath, MSc\nShruthi Narendranath is an analyst within the Cardiovascular Medtech Insights team at Decision Resources Group, specializing in heart valve and periphral vascular device markets. Shruthi holds a Master's degree in Bioinformatics from Cardiff University.", "pred_label": "__label__POS", "pred_score_pos": 0.99126797914505}
{"content": "The lasting legacy of the sixth presidential summit held in Cartagena, Colombia on 14th and 15th April will likely be the beginning of a serious regional debate on international drug control policies. With the adept leadership of Colombia’s President Juan Manuel Santos, the issue was discussed at a private, closed-door meeting of the presidents. Santos later announced that, as a result, the Organisation of American States (OAS) would be tasked with analyzing the results of present policy and exploring alternative approaches that could prove to be more effective. A topic long considered taboo, the U.S. “war on drugs,” is now being seriously questioned and debate on new strategies – including legal, regulated markets – is officially on the regional agenda.\nWhile making it clear that no change in U.S. policy is in the offing, Washington has reluctantly agreed to participate in a debate. The United States is no doubt pleased that the OAS was tasked to study the issue. The Secretariat of its Inter-American Drug Abuse Control Commission (CICAD) is traditionally led by someone appointed by the U.S. government (presently it is former U.S. diplomat, Amb. Paul Simons) and it is widely perceived across the region as a U.S.-driven agency. However, ultimately, CICAD’s agenda and focus is dictated by member states. The burden is now on those member states advocating reform to ensure that the OAS effectively carries out its mandate to explore all alternative policies and to include in the discussion relevant experts and organizations.\nPresent international drug control policies are deeply-rooted and change will no doubt come slowly. However, an opportunity for meaningful drug policy reform has emerged in Latin America.\nKeep up-to-date with drug policy developments by subscribing to the IDPC Monthly Alert .", "pred_label": "__label__POS", "pred_score_pos": 0.5721908807754517}
{"content": "Show/Hide MenuHide/Show AppsanonymousUserLogoutTürkçeTürkçeSearchSearchLoginLoginOpenMETUOpenMETUAboutAboutAçık Bilim PolitikasıAçık Bilim PolitikasıFrequently Asked QuestionsFrequently Asked QuestionsBrowseBrowseCommunities & CollectionsCommunities & CollectionsBy Issue DateBy Issue DateAuthorsAuthorsTitlesTitlesSubjectsSubjectsHaptic feedback enhances rhythmic motor control by reducing variability, not improving convergence rateDownloadindex.pdfDate2014-03-01AuthorAnkaralı, Mustafa MertSen, H. TutkunDe, AvikOkamura, Allison M.Cowan, Noah J.MetadataShow full item recordThis work is licensed under aCreative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.Stability and performance during rhythmic motor behaviors such as locomotion are critical for survival across taxa: falling down would bode well for neither cheetah nor gazelle. Little is known about how haptic feedback, particularly during discrete events such as the heel-strike event during walking, enhances rhythmic behavior. To determine the effect of haptic cues on rhythmic motor performance, we investigated a virtual paddle juggling behavior, analogous to bouncing a table tennis ball on a paddle. Here, we show that a force impulse to the hand at the moment of ball-paddle collision categorically improves performance over visual feedback alone, not by regulating the rate of convergence to steady state (e.g., via higher gain feedback or modifying the steady-state hand motion), but rather by reducing cycle-to-cycle variability. This suggests that the timing and state cues afforded by haptic feedback decrease the nervous system's uncertainty of the state of the ball to enable more accurate control but that the feedback gain itself is unaltered. This decrease in variability leads to a substantial increase in the mean first passage time, a measure of the long-term metastability of a stochastic dynamical system. Rhythmic tasks such as locomotion and juggling involve intermittent contact with the environment (i.e., hybrid transitions), and the timing of such transitions is generally easy to sense via haptic feedback. This timing information may improve metastability, equating to less frequent falls or other failures depending on the task.Subject KeywordsHaptics,Juggling,Metastability,Limit cycle,Multisensory integrationURIhttps://hdl.handle.net/11511/33372JournalJOURNAL OF NEUROPHYSIOLOGYDOIhttps://doi.org/10.1152/jn.00140.2013CollectionsDepartment of Electrical and Electronics Engineering, ArticleMETU IIS - Integrated Information ServiceIT Support ServiceYou can transmit your request, problems about servicesprovided by METU Computer Center, and follow the process.", "pred_label": "__label__POS", "pred_score_pos": 0.8908414244651794}
{"content": "Storing Your Precious Metals: 3 Ways to Do That\nStorage is a significant factor to consider when investing in precious metals like gold, silver, or platinum. Once you’ve purchased coins, bars, or jewelry, it’s normal to start wondering how to keep them safe and secure.Finding the right storage space is a pivotal decision, and fortunately, it isn’t a difficult one.\nThere are three ways to store precious metals, and it’s imperative to choose the one that offers the maximum security for your investments.\n1. Home Storage\nPrecious metals are highly valuable, so they need to bestored with care. It’s important to ensure that these assets are hidden and secured. These considerations make a home storage plan critical. Here’s a quick & quintessential checklist for properly storing precious metals at home:\nChoose a secretive spot if you own a small to a medium-sized precious metal collection. Common practices include concealing them in a hollow book or hiding them behind a removable tile. Safes are a more effective way of storing precious metals. Their unique pin code option offers extra security and theft resistance. Ensure your valuables’ safety by purchasing a UL (Underwriters Laboratories) rated safe of UL-15 spec or higher. Make sure the metals are wrapped in moisture-free lock bags to prevent any physical damage. 2. Bank Lockers\nIf you’re uncomfortable with the idea of storing your precious metals at home, consider keeping them in lockers at your local bank.\nBy opting for bank lockers, you ensure peace of mind and relieve yourself ofthe responsibility of safeguarding the assets. There are two ways to store your precious metals at a bank:\nSafety Deposit Box: A single-customer-use box that’s available in various sizes to accommodate customers’ needs. Bank Vault: Designed to store bulk bullions that belong to various customers who own large precious metals collections.\nYou’ll have to pay a fee for availing the storage facility at banks. Another drawback of storing precious metals at banks is that you have limited access to your assets, i.e., only during business hours. You may also face hurdles in accessing your valuables on federal holidays that may coincide with financial emergencies.\n3. Precious Metal Depositories\nStoring precious metals in specialized storage depositories is the best option by far. The facility is designed for all your precious metal support storage, security, and maintenance needs. Here’s why you should consider the private vault storage option:\nPrecious metal depositories have a moisture-controlled climate in the storage vaults to keep temperature damage at bay. They offer optimum security and constant surveillance. All the activities inside the depository are recorded to maintain a highly secure environment. They also offer further protection for your peace of mind with auditing and insurance policies.\nMoreover, there are two types of storage options provided at metal depositories:\nSegregated Storage: This option offers a secluded space where customers can keep their precious assets separately. The storage compartment is provided for single-person usage, but the security level is as high as in a shared storage vault. Shared/Communal Storage: You can also choose to store your assets in a shared storage area where other customers’ valuables are kept along with yours. Choose Specialized Metal Storage to Safeguard Your Assets\nFor full details, get in touch with our account executive today!", "pred_label": "__label__POS", "pred_score_pos": 0.5546349287033081}
{"content": "Sammanfattning\nThis paper studies whether tourism policies enhance regional development, and how such effects are distributed by the rural-urban sphere in two structurally different rural regions in Finland. The overall GDP and employment effects were positive in both examined regions whether the main beneficiary was a rural or urban area. The tourism policies generated comparatively uniform gains in the diversified economic region in which the natural environment was the main tourist attraction. However, in the region where the food cluster was at the core of the economy, the gains were smaller and tended to accumulate in the urban area.\nVetenskapsgrenar 5142 Social- och samhällspolitik 415 Övriga jordbruksvetenskaper 519 Socialgeografi och ekonomisk geografi", "pred_label": "__label__POS", "pred_score_pos": 0.7142540216445923}
{"content": "Facts About Corporate Social Media\nJust a few years ago, social media was a fairly obscure concept. However, its popularity has grown so rapidly that some social networking sites have millions of users around the world. Corporations have also joined in, and it's becoming increasingly rare to find a business that doesn't have at least a minimal social media presence. It's crucial, though, that companies research the risks and benefits of social media and create strategies that take these factors into account.\nTypes\nSocial media is a broad category that includes social networking sites, blogs, online review sites and photo- and video-sharing sites. It also includes sites where users can \"check in\" at their location, such as a restaurant or movie theater, and share their experiences and opinions. Social media includes both sites run by the company, such as its own blog or website, and third-party sites where users can \"friend\" or \"follow\" each other. Companies often combine both strategies to reach the largest audience possible. For example, they may create a profile on a popular social networking site, and then encourage followers to visit their own blog or website for special offers.\nBenefits\nSocial media can enhance a company's marketing strategy by allowing it to reach a new or wider audience. While its message may reach a significant adult audience through traditional mediums such as television or print advertising, using social media may help it more effectively reach younger consumers, who often get most of their news, information and entertainment from the Internet. Because social media is more interactive than many traditional marketing mediums, it can enhance the relationship between the company and consumers. For example, if the company uses social media to ask customers to offer feedback and opinions, customers will feel their thoughts matter to the company, potentially increasing their loyalty.\nRisks\nWhile social media allows companies to quickly spread their message to a massive and diverse audience, it also brings risks that companies must consider. The various sites cater to vastly different audiences, so it's crucial that companies identify the target audience for each site and tailor their messages accordingly. For example, some sites appeal primarily to teenagers or college students, so you can't use the same message you'd use to attract a middle-aged audience. Also, once you send out a message via social media, you can't take it back even if you delete it. By then, thousands of people may have shared your status update or blog post. In addition, anything you post is considered public information, and you could see it quoted in the media.\nPolicies\nEstablishing company social media policies can prevent public embarrassment or misunderstandings. Tell employees exactly what they're allowed to share on the company's social media profiles and what information is prohibited. Create a list of words, phrases or other language employees shouldn't use when posting on behalf of the company. Also, create a strategy for interacting with the public via social media, for example, if customers post complaints about the company online. Decide whether employees are authorized to reach out directly to dissatisfied customers, or if they must pass the message along to another department.", "pred_label": "__label__POS", "pred_score_pos": 0.8632532358169556}
{"content": "What are GMOs?DOWNLOAD FILE\nSeptember 27, 2020 - Author: MSU Extension\nA genetically modified organism, or GMO, is a plant, animal, or other organism that has had a gene from another organism transferred into it as an addition or a replacement. The goal of the new gene is to produce a helpful trait or characteristic in the modified organism, such as disease resistance, drought tolerance, or improved nutritional value. Conventional breeding lacks this kind of precise control.\nWhat foods are considered GMOs? By 2019, federal regulators had approved 11 GMO crops for sale in the United States. Corn (field and sweet) Soybeans Cotton Alfalfa Sugar beets Canola Papaya Summer squash Innate potatoes Pink pineapple Non-browning Arctic apples", "pred_label": "__label__POS", "pred_score_pos": 0.6768298745155334}
{"content": "India Prohibits FATCA Account Closures\nIndia and the USA entered into a Model 1 IGA for implementation of FATCA on 31st August, 2015. As part of the IGA implementation, India’s income tax rules included an alternate procedure for due diligence (Rule 114H(8)).\nThis rule required financial institutions to obtain self-certifications from account holders who had opened new accounts as of 1 July 2014. The due diligence process also included a requirement that the financial institution determine the reasonableness of the submitted self-certifications. If the financial institution determined that the self-certification was unacceptable and the account holder failed to cure the defect by 31 August 2016, then the financial institution was required to close the account. Under Rule 114H(8), the financial institution was also required to report the account if it were found to be a “reportable account.”\nIndia’s Central Board of Direct Taxes (CBDT) acknowledged the complexity of following these due diligence rules and announced that Indian financial institutions may not close accounts by 31 August 2016 due to non-receipt of a valid self-certification from the account holder.\nThe CBDT is in discussions with the USA with the goal of extending the 31 August 2016 account closure deadline a few months. Pending a further announcement from CBDT, Indian financial institutions should continue to work on completing the required due diligence, including obtaining self-certifications.", "pred_label": "__label__POS", "pred_score_pos": 0.9959942102432251}
{"content": "Summary: Many executives have come to feel that rapidly evolving brand and agency roles and responsibilities are having a negative impact on business results, creating a series of challenges. To investigate this issue, Forbes Insights, in collaboration with Oracle Marketing Cloud, conducted a global survey of 255 executives across a range of functions in the fourth quarter of 2015. Seventy-five percent of respondents were involved in providing internal brand support for their companies; 12% were from agencies; 13% were from technology vendors that support marketing programs. Sixty-five percent had C-level titles; the rest were VP/Director or above. Forty- nine percent of respondents were based in North America; 24% in Europe; 18% in Asia-Pacific; and 9% in Latin America. Forbes Insights also conducted qualitative interviews with senior executives. To download a pdf of the study, please fill out the following information. If you experience any trouble, please send an email to: insights@forbes.com. Notice: By supplying my contact information, I authorize Forbes Insights and the report sponsor to contact me about the sponsor’s products and services. Forbes Insights may use data I have provided in accordance with the Forbes online privacy policy.", "pred_label": "__label__POS", "pred_score_pos": 0.8078197240829468}
{"content": "Five people, three of them children, were pronounced dead following a serious car crash on the Pacific Coast Highway, as reported by local news sources. California Highway Patrol has confirmed that five people were involved in the single-car motor vehicle accident. No charges are likely, as all occupants of the car including the driver were killed, but legal recourse may be available to the families of the deceased.\nPolice are still puzzled as to how the accident occurred. California authorities have confirmed that an SUV was traveling southbound on Highway 1 when, for reasons unknown, it pulled into a dirt turnout before driving directly off a cliff. The vehicle fell some 100 feet into the rocky shore of the Pacific Ocean, killing all five passengers on impact. The relationship between the individuals in the car, including the three children, is not yet known.\nWhile drugs and alcohol were not considered a factor in the accident, authorities say autopsies will be performed on all five individuals. It has been confirmed that the two adult women in the vehicle were from out of state, though the identities of the children remain unknown. The investigation is still underway as of this report.\nObviously the death of five people, especially children, is a tragedy. However, it will be up to California authorities to determine the cause of the motor vehicle accident, which will inform the families of their options in seeking legal recourse. State law will allow them to file wrongful death suits against the driver’s estate if it can be confirmed that driver error of some type was responsible for the crash.\nSource: popculture.com, “5 Dead After Car Plunges off Cliff on Pacific Coast Highway“, Hannah Barnes, March 28, 2018", "pred_label": "__label__POS", "pred_score_pos": 0.9882494211196899}
{"content": "Curator: Manuela Lietti\nAlthough we may be more technologically sophisticated than our ancestors, we are just like them in that we are immersed in the perpetual and challenging quest for self-knowledge.\nDespite the fact that its time and place of origin is still shrouded in mystery, the adage “know thyself” is universal, placed at the foundation of knowledge and regarded as the cornerstone on which an entire philosophical system has been erected. The Greek philosopher Plato claimed, “The essence of knowledge is self-knowledge.” Centuries before him, the Hindu Upanishads confirmed that “enquiry into the truth of the Self is knowledge.” Reflecting the social, political, and cultural complexity shaping modern man centuries later, Nietzsche declared, “One’s own self is well hidden from one’s own self; of all mines of treasure, one’s own is the last to be dug up.” In contrast, André Gide cynically noted, “Any caterpillar who tried to ‘know himself’ would never become a butterfly.” Famous opinions on this matter would make a long and multi-faceted list, but regardless of which of the above viewpoints we embrace, self-knowledge is an all-encompassing journey. It is a crucial step on the path that determines an individual’s humanity and leads him to the full awareness of his being.\nSelf-Staging is a group exhibition presenting six artists from five countries (Canada, China, Israel, Italy, and Poland) who work in video, painting, installation, and printing to explore the self from both micro and macro perspectives. Far from being an exhaustive compendium on the topic, which would be a challenging and anachronistic task in an increasingly fragmented, decentralized reality, Self-Staging analyzes different approaches to the idea of identity through case studies. Even though the Self is no longer a monolithic entity, from certain points of view it remains unfathomable and unpredictable. The exhibited pieces declare the loss of the traditional notion of identity and react to this loss. The works investigate and question the cognitive, social, and cultural processes that shape identity; they reflect on the subtle boundary between the individual and the outside world, the private self and the public persona. As suggested by the title of the exhibition, identity is more performative than predetermined; it is related to\nmise-en-scène (placing on stage), combining strong theatrical elements and documenting the artist’s diverse strategies for dealing with (auto) biographical material. Artists rely on their selves and bodies in the same way that actors rely on props to become their characters. No absolute lies, but many multi-layered truths, are displayed before our eyes to assist in the ongoing epiphany of “self-editing” carried out by the artists exhibited.", "pred_label": "__label__POS", "pred_score_pos": 0.5421513319015503}
{"content": "Toast Ale has launched a ‘meal deal’ initiative to help feed vulnerable people amidst the Covid-19 crisis.\nThe social enterprise, which uses surplus bread to brew beer, has committed profits from online sales to support community feeding projects – equating to roughly one meal for every bottle or can of beer purchased. The initiative will also see Toast Ale’s furloughed team volunteering their time to help redirect surplus food, that would otherwise be wasted, to those in need.\nDonations are being backdated to 1 March and will run for at least the next 12 weeks. As a result, sales in March alone will fund 5,724 meals for vulnerable communities.\nLiverpool-based Alchemic Kitchen – which repurposes surplus produce, while connecting vulnerable communities – is the first project being supported by Toast. It has rapidly adapted to prepare, cook and distribute meals to those who are struggling to access food and is currently serving about 100 meals each week. With Toast’s support it will be able to scale up quickly.\nAs the Liverpool project reaches capacity, funding will be directed to similar programmes in London, Sussex and Kent. Ultimately, Toast aims for the Meal Deal campaign to fund feeding operations across the country, with overheads covered by existing funding streams so money raised by Toast can go directly to serving food to those in need.\nThe meals will be distributed primarily through the brewery’s existing charity partner Feedback.\nSince partnering with the charity in 2016, Toast has donated more than £25,000.", "pred_label": "__label__POS", "pred_score_pos": 0.7075402140617371}
{"content": "NCASE Resource Library Featured Resources\nThis publication features some of the best resources, including webinars, briefs, and toolkits, available in the online NCASE Resource Library, developed for both practitioners and system builders.\nThese selected resources, curated by NCASE, offer ideas and information for OST system leaders to support recovery from COVID-19.\nThe NCASE Out-of-School Time Professional Development System-Building Toolkit was designed to assist states as they build professional development systems inclusive of school-age providers.\nSearch for Resources ? Search Results Filter By Reset Selections Expand All Filters Topics Resource type Publisher Search Results Filter By\nThis issue brief and its video clips explore trauma-informed practices implemented in a Nashville, TN school. While the strategies are implemented in a school, the information and the videos on a whole-school approach, peace corners, mentor relationships, and teacher supports are relevant for out-of-school programs. This resource supports the COVID-19 response.\nThis blog highlights key elements of quality in camp experiences, whether virtual or in person, such as building strong relationships and creating safe spaces. It offers frameworks for designing strong programs and as it is a quick but thought-provoking read, it could be an effective tool for staff professional development. This resource supports the COVID-19 response.\nThis guidance from the CDC includes important information specifically for child care centers that are open during the pandemic.\nThe interim guidance from the CDC includes important information for schools and child care centers in both English and Spanish. It includes a fact sheet about children and COVID-19 and a document on how to stop the spread of the virus. It was updated March 12, 2020. This resource supports the COVID-19 response.\nThese State Fact Sheets provide a state-by-state overview of child and family demographics, child care availability, and participation rates in QRIS. School-age state system planners can find information on the number of children and families, available school-age slots, affordability, and number of programs participating in QRIS and at what level.\nChild Care Aware created this web-based school-age program checklist to help families select a high quality school-age program. It has questions on topics like health and safety, indoor and outdoor environment, caregiver-child interactions, staff qualifications, and parent partnerships. There is a link to print out the five-page checklist.\nThis video provides a unique overview of the important role afterschool has played in American history, beginning in the 1880's with the age of industrialization. It is broken into 12 brief chapters that captures the social upheaval of the late 1800's, then the growing need for supervision into the 1900's, and the rapid growth over the past 50 years.\nThis video on social-emotional learning (SEL) examines core capabilities known as executive function and self-regulation skills. It explores what these skills are, why they are important, how they develop, and how they are negatively affected by stress for children, adolescents, and adult caregivers. This resource supports resilience.\nThis PowerPoint presentation explores key principles for effective business management. It describes the concept of shared services. Some slides demonstrate the extensive resources of the ECE Shared Resources tool used by more than 20 states. It provides examples of strengthening business practices in New Hampshire and Pennsylvania.", "pred_label": "__label__POS", "pred_score_pos": 0.581506609916687}
{"content": "The first webinar will take place on\nMonday 23 November 9:30-11:00 am (Central European Time). In this webinar you will be welcomed by Jeroen Geurts, President of the Netherlands Organisation for Health Research and Development (ZonMw) and board member of the Dutch Research Council (NWO). The webinar will be moderated by Ruth Graham.\nIn the webinar, we will introduce the challenges and opportunities of reforming institutional reward systems, from a range of different perspectives. Our invited speakers will provide us with insights regarding implemented changes in their organizations, the opportunities and challenges they face during the change process and their current or upcoming activities to enhance the process.\nWhen we have gained new insights from these speakers, the webinar provides room for questions and discussion among all participants.\nSpeakers:\n·\nJoe Chicharo (University of Wollongong, Australia)\n·\nManon Kluijtmans (Utrecht University, Netherlands)\n·\nSam Smidt (UCL, UK)\nYou can sign up for the webinars through a form on the VSNU website.\nOn behalf of the Dutch Recognition & Rewards network,\nKim Huijpen\nOn behalf of the Comenius Network, Ilja Boor and Marion Tillema.", "pred_label": "__label__POS", "pred_score_pos": 0.6370260119438171}
{"content": "Catch of the Week: Tacoma foundry pays 10.8M settlement over deficient steel parts destined for U.S. Navy submarines, falsified tests June 18, 2020\nThe latest in our Catch of the Week series features Bradken Inc.’s $10.8 million payment to resolve allegations that its Tacoma foundry violated the False Claims Act (“FCA”) when it produced and sold substandard steel parts for U.S. Navy submarines and falsified test results to hide the failures. Bradken and its former lab director Elaine Thomas also face criminal charges. The company accepted responsibility and agreed to take remedial measures in a deferred prosecution agreement.\nBradken, a major steel supplier for naval submarines, produces castings destined for submarine hulls. According to the Department of Justice, the Tacoma foundry produced castings that failed lab tests and did not meet the Navy’s standards for steel strength and toughness, which are designed to ensure that submarines can withstand circumstances like collisions. Court filings further allege that Thomas, former Bradken Director of Metallurgy, fabricated test results for over 200 steel productions, a significant portion of the castings Bradken sold to the Navy.\nWhen a lab employee discovered testing discrepancies in 2017, the company disclosed the issue to the Navy. But Bradken then made misleading statements suggesting that the discrepancies were not the result of fraud. These representations impeded the Navy’s investigation and remediation efforts.\nThe Department of Justice’s press release highlighted the resulting risks to safety and naval operations: “Bradken placed the Navy’s sailors and its operations at risk. Further, after Bradken’s management discovered the falsified data, they misled the Navy about the scope and nature of the fraud. Government contractors must not tolerate fraud within their organizations, and they must be fully forthcoming with the government when they discover it,” said U.S. Attorney Brian T. Moran.\nCompany insiders or other individuals who learn of similar fraud and misconduct in government contracting can report it to the government and initiate a lawsuit on the government’s behalf under the FCA’s\nqui tam provisions. Successful whistleblowers are entitled to share in the government’s recovery. If you would like more information or would like to speak to a member of Constantine Cannon’s whistleblower lawyer team, please click here.", "pred_label": "__label__POS", "pred_score_pos": 0.6762456893920898}
{"content": "Join us for the next joint-hosted IBEST/CMCI seminar on\nThursday, September 13, 12:30 p.m. in EP 122. Sean Gibbons from the Washington Research Foundation will present, “ How do we model gut microbial dynamics?“\nAbstract:\nDynamics reveal crucial information about how a system functions. However, it is not yet known what the relevant timescales or models are for understanding microbial dynamics in the gut. For example, gut microbial population dynamics may be largely internal, and the stool samples we obtain likely represent the end-point of these internal dynamics. In this talk, I describe a statistical approach for disentangling different components of dynamics within the human gut microbiome: autoregressive and non-autoregressive. Autoregressive dynamics involve recovery from large deviations in community structure. These recovery processes appear to involve the blooming of facultative anaerobes and aerotolerant taxa, likely due to transient shifts in redox potential, followed by re-establishment of obligate anaerobes. Non-autoregressive dynamics carry a strong phylogenetic signal, wherein highly related taxa fluctuate coherently. These non-autoregressive dynamics may be driven by external, non-autoregressive variables like diet. Most of the community variance is driven by day-to-day fluctuations in the environment, with occasional autoregressive dynamics as the system recovers from larger shocks. Despite frequently observed disruptions to the gut ecosystem, there exists a strong returning force that continually pushes the gut microbiome back towards its steady-state configuration.\nCheck out the Gibbons Lab website here.", "pred_label": "__label__POS", "pred_score_pos": 0.9989006519317627}
{"content": "Abstract\nSemisupervised classification aims to construct a classifier by making use of both labeled data and unlabeled data. This paper proposes a semisupervised classifier based on a piecewise linear regression model implemented by using a gated linear network. The semisupervised classifier is constructed in two steps. In the first step, instead of estimating the break points of a piecewise linear model directly, a label-guided autoencoder-based semisupervised gating mechanism is designed to generate binary gate control signals to realize the partitioning. In the second step, the piecewise linear model is first transformed into linear regression form, and the linear parameters are then optimized globally by a Laplacian regularized least squares (LapRLS) algorithm using a kernel function comprising the gate control signals obtained in the first step. Moreover, the composed kernel function is used as a better similarity function for the graph construction. As a result, we capture data manifold from both labeled and unlabeled data, and the data manifold is ingeniously incorporated into both the kernel and the graph Laplacian in LapRLS. Numerical experiments on various real-world datasets exhibit the effectiveness of the proposed method.\nOriginal language English Pages (from-to) 1048-1056 Number of pages 9 Journal IEEJ Transactions on Electrical and Electronic Engineering Volume 15 Issue number 7 DOIs Publication status Published - 2020 Jul 1 Keywords graph construction kernel composition Laplacian RLS piecewise linear regression model semisupervised learning ASJC Scopus subject areas Electrical and Electronic Engineering", "pred_label": "__label__POS", "pred_score_pos": 0.5840467214584351}
{"content": "Witnesses to a Will\nA significant piece of validating a will is verifying that the will was properly witnessed. If you or a loved one has a will more than five years old, consult with a lawyer to verify it won’t be invalidated because of insufficient proof of who witnessed the signing of the will.\nThe witnesses to the will are as critical to the validation process as your signature at the bottom of the will. Today, most wills come with documents (self-proving affidavits) to prove the identity of those who witnessed the will. Without that documentation, the executor has to track down the witnesses and provide proof of their identity.\nWithout the self-proving affidavits, there are legal options to prove the identity of the witnesses even if they have passed away. While time consuming and expensive, verification by a hand-writing specialist is generally acceptable by modern probate courts.\nIf you’ve gone through the trouble of having written a will, ask a legal professional to review your will and ensure the witness verification paperwork is sufficient. If you don’t have a will, or your will is out of date, hire an estate attorney to guide you through the logistics of creating an iron-clad document.", "pred_label": "__label__POS", "pred_score_pos": 0.6265741586685181}
{"content": "\"How do you want to feel?\"\nNext time you're about to make a decision, I want you to consider something:\nEverything we do, we do for a feeling. Either we want a particular feeling, or we're trying to avoid one.\nEven decisions that seem purely logical are often fueled by feelings. For example, when looking at financial plans, you may think you're comparing them based solely on the numbers. But look at your decision-making from a feelings perspective, and you'll discover deeper truths. One plan may give you a feeling of security and trust (thereby avoiding anxiety and fear), while another makes you feel excited and bold (thereby avoiding boredom and missing out). The feeling you want (or don't want) ultimately determines which plan you choose.\nIn trying to create the lives we desire, we often ask ourselves, \"What do I want?\" However, this question is insufficient because:\nWhat we want often isn't that thing - what we want are the feelings we expect that thing will give us.\nFor example, a man may think he wants a red Ferrari, but what he may really want is to feel sexy, confident, and the envy of his friends and colleagues. A woman may think she wants a relationship with a guy who satisfies every item on her checklist, but what she may ultimately want is to feel loved, accepted, understood, and cared for.\nTherefore, in creating the lives we desire (and in every situation in our lives, for that matter), the most powerful and effective question to ask ourselves is:\n\"How do I want to feel?\"\nIt bypasses the analytical left brain, cutting through to the very marrow of what you desire - not just what you think you desire (which can be influenced by shoulds, expectations, and marketing).\nNot only that, it massively shifts your energy field, thereby magnetizing to you what will bring you those feelings - whether in work, home, relationships, health, etc. And the results can be truly surprising!\nMy marriage is a perfect example. My husband and I were friends for many years before we started dating. In all those years, I never once thought of him romantically. However, after my life completely fell apart, I started focusing less on what I wanted and more on how I wanted to feel. Before long, he and I reconnected, and, much to my surprise, how I feel in our relationship is what I've always desired - and more! The Universe knew better than I that we were a match!\nStop trying to figure out how to get what you want, and start asking yourself how you want to feel...\nAnd let me know how it goes.", "pred_label": "__label__POS", "pred_score_pos": 0.8138855695724487}
{"content": "Washington DUI Attorney Mark W. Garka Says Not All DUI Arrests Are Legitimate\nNot all arrests for driving under the influence are legitimate or provable beyond a reasonable doubt. In fact, certain medical conditions can mimic the symptoms of drug or alcohol intoxication, as evidenced by the December 2017 arrest of a 64-year-old woman from Edmonds who had not been drinking. Although arresting officers said the driver, Mrs. C. Carlson, appeared disoriented, with bloodshot eyes, and failed a field sobriety test, she was not, in fact, intoxicated. Instead, after considerable twists and turns in her extraordinary story, the Kitsap County prosecutor dismissed her DUI charge in July 2018 based on the fact that no alcohol had been detected in her blood administered after her arrest, and her symptoms of disorientation were attributed to a stroke diagnosed in the weeks following her arrest.\nMrs. Carlson was released from the Port Orchard Jail the morning following her arrest, but she then proceeded to wander the surrounding streets in a mental fog, without a coat, her cellphone, or medications for four days. She eventually wound up in a Bremerton homeless shelter and was only taken to a doctor after she suffered a seizure. While at the hospital, she was eventually diagnosed as having had a stroke at some point in the days leading up to her DUI arrest. A year after her unfortunate arrest, Mrs. Carlson is still recovering and piecing together the details of the time she lost because of the stroke-induced amnesia. She has since regained her ability to speak, her balance has returned, and she hasn't had another seizure. To date, she continues to live independently at her Edmonds home.\nThis is not the only instance of a driver being arrested on suspicion of drunk driving resulting in the prosecutor dropping the charges. As a former prosecutor myself, I know how these attorneys think and how they go about assembling a case against a DUI suspect. Evidence of a blood alcohol level above 0.08% is usually absolutely necessary to clinch a conviction, and yet Mrs. Carlson had no alcohol detected in her blood. Because of this, the events following her arrest were particularly unusual and showed poor insight by the arresting officers.\nNot all DUI cases are straightforward. Although few can claim such a remarkable story as Mrs. Carlson's, it is possible to be found innocent of drunk driving if the prosecution cannot prove their case beyond a reasonable doubt. If you or your loved one has been arrested for drunk driving, don't delay seeking legal representation from a DUI attorney with trial experience.\nDo not hesitate: Contact me, Attorney Mark Garka, at (888) 252-1961 for a free consultation in Snohomoish County.", "pred_label": "__label__POS", "pred_score_pos": 0.5528457164764404}
{"content": "A senior manager’s new model can help employers to support career progression\nAs a senior manager in the NHS, I provide practical support to colleagues and peers to help them navigate recruitment processes. My mission is to transform how healthcare providers support the career development of black, Asian and minority ethnic (BAME) nurses and other healthcare professionals, with the aim of all employers having a dedicated career development service for their BAME workforce.\nNursing Management.\n27, 5, 18-19.\ndoi: 10.7748/nm.27.5.18.s7\nAlternatively, you can purchase access to this article for the next seven days. Buy now", "pred_label": "__label__POS", "pred_score_pos": 0.8744907975196838}
{"content": "Trauma-informed approaches within primary care can support more effective care for individuals with a history of trauma, improve patient outcomes, and increase staff satisfaction. This change package is a comprehensive toolkit developed by trauma-informed care experts and refined through pilot testing at seven primary care organizations across the United States. It outlines foundational change management strategies to create the conditions for successful change within primary care organizations, including: developing a core implementation team; ensuring continued leadership support; and conducting an organizational self-assessment.\nAfter initiating the change management strategies, organizations can use the following implementation strategies: (1) help all individuals feel safety, security, and trust; (2) develop a trauma-informed workforce; (3) build compassion resilience in the workforce; (4) identify and respond to trauma among patients; and (5) finance and sustain trauma-informed approaches in primary care. For each of these strategies, the toolkit offers resources to address action steps, tools, key considerations, checklists, quick tips, sample scripts, and case examples. This change package is designed for a diverse range of primary care settings with varying sizes, populations served, levels of behavioral health integration, and staff compositions.", "pred_label": "__label__POS", "pred_score_pos": 0.9965035319328308}
{"content": "How COVID-19 affects Census 2020 U.S. Census Bureau Updates on COVID-19 and its Effect on Operation The U.S. Census Bureau released an update on Census 2020 Field Operations on March 28th. While field operations are still paused, the 2020 Census is still open and able to be responded to.\n\"Based on continuing assessments of guidance from federal, state and local health authorities, the U.S. Census Bureau is suspending 2020 Census field operations for two additional weeks to April 15, 2020.\"\nRespond to the 2020 Census yourself:\nThe Census Bureau released a March 11th COVID-19 press release and March 15th Group Quarters press release on COVID-19. They have confirmed they are encouraging self-response methods online, by phone, or by mail to ensure a Census Bureau employee does not have to visit the home to complete the Census.\nThe Census Bureau has encouraged the following messaging: “It has never been easier to respond on your own, whether online, over the phone or by mail—all without having to meet a census taker.”\nCOVID-19\nThis is the perfect time to encourage self-response to bring a benefit out of a bad situation. This will encourage early self-response during a time when more people are asked to stay home which could increase the chances of a complete and accurate count regardless of displacement from the pandemic.\nStudents who are temporarily displaced because of COVID-19 should still be counted as though they are living where they normally would be. This ensures they are accurately counted per the residence criteria being the place they live and sleep most.\nOn-campus students who are currently offsite due to COVID-19 closures are normally counted at the institution by the Census Bureau. This furthers the general messaging that parents should also be informed that students living on-campus are traditionally counted at their institution by the Census Bureau through group quarter enumeration.\nEarly Nonresponse Follow-Up Operations, which happen often in college towns, will have a delayed start of April 23. There should be messaging for college towns to ensure off-campus students know to complete their Census form with roommates as though they were still living where they would normally be. Only one resident of the house or apartment needs to complete the form for all residents staying there normally.\nThe Census Bureau Group Quarters is contacting service providers like emergency and transitional shelters, soup kitchens and regularly scheduled mobile food vans to determine whether they will be open between March 30 and April 1 and whether they would be able to provide a paper listing of census response data for each person served or staying at the facility instead of the traditional March 30-April 1 in-person interviews.\nContact the U.S. Census Bureau's Atlanta Regional Office for concerns on group quarter enumeration in the state of Georgia: Atlanta Regional Office\n101 Marietta Street, NW, Suite 3200\nAtlanta, GA 30303-2700 (404) 730-3832 or 1-800-424-6974 FAX: (404) 730-3835 TDD: (404) 730-3963 E-mail: Atlanta.Regional.Office@census.gov", "pred_label": "__label__POS", "pred_score_pos": 0.7801263332366943}
{"content": "Record keeping is an essential aspect of any business, but the federal government sets very specific standards for record keeping by auto dealerships. Because the activities of this type of business can affect so many interests, businesses must retain numerous records. Auto dealers can eventually purge many of their records, but they must retain them for certain time periods, depending on the type of record, as set by the federal government.\nDepartment of Transportation\nThe U.S. Department of Transportation requires auto dealerships to retain odometer mileage statements for five years. They must keep the names and addresses of tire purchasers for three years. Dealers must keep air bag switch installation forms indefinitely.\nBecause keeping vehicles safe requires maintenance, the government scrutinizes the people who do this work. Dealers must keep safety compliance reviews indefinitely. They must retain accident records and brake inspector qualifications for one year, and inspection and maintenance records for 14 months, or for six months after the vehicle is sold. Dealerships must retain records of employee drug testing for five years if tests are positive and one year if they are negative.\nEnvironmental Protection Agency\nAuto dealerships must follow several U.S. Environmental Protection Agency regulations. They must retain hazardous waste and oil records--including hazardous waste shipment reports, hazardous waste determination lists and waste test results--for three years.\nBecause underground storage tanks, or USTs, pose a serious environmental threat, auto dealers must keep records pertaining to them on file. They must retain new UST design, construction, installation and notification records, UST repair documents and financial responsibility records indefinitely, and UST leak detection reports for five years.\nFederal Trade Commission\nThe Federal Trade Commission requires auto dealerships to retain certain records. Equal-opportunity credit applications must be kept for 25 months. Dealers must retain Truth in Lending Act and Truth in Leasing Act disclosure statements for two years.\nThey must retain indefinitely documents relating to the sale of cars, such as buyers' guides, sales contracts, and warranty and service contracts. They must keep records of the sale of auto parts for six years.\nEmployment and Sales Records\nAuto dealers must keep numerous records relating to employees. They must retain sales compensation records, time cards and daily sales records for three years.\nDealers must retain inventory records: dealer vehicle reassignment forms, consignment contracts and vehicle purchase contracts for three years, and records of the inventory of new vehicles for two years.\nReferences\nWriter Bio\nJohn Toivonen is an attorney in Lansing, Mich., and has been a professional writer since 1999. His work has appeared in \"The Washington Times.\" He holds a Juris Doctor from Thomas M. Cooley Law School and a Bachelor of Arts in English from Guilford College.", "pred_label": "__label__POS", "pred_score_pos": 0.903997540473938}
{"content": "Digest Pro contains a special blend of digestive enzymes with botanicals such as fenugreek, ginger and fennel which help support the digestive system. Formulated with Lactase enzyme.\nBenefits:\n– May help support the body’s natural digestive process*\n*provides fenugreek, ginger and fennel\nTake 1–2 capsules with meals, or as your health professional advises.\nIngredients:\nProtease, vegetarian capsule (hydroxypropyl methylcellulose), fenugreek seed powder, ginger rhizome powder, fennel seed powder, amylase, invertase, glucoamylase: (preservatives: sodium benzoate, potassium sorbate) bulking agent (rice bran), lipase, peptidase, diastase, xylanase: (preservative: potassium sorbate), cellulase: (preservative: sodium benzoate), lactase\nFree From:\nYeast\nArtificial flavourings Gluten-free\nIf you are under medical supervision, please consult a doctor before use. Do not exceed recommended daily intake. Food supplements should not be used as a substitute for a varied and balanced diet and healthy lifestyle. Keep out of reach of children.", "pred_label": "__label__POS", "pred_score_pos": 0.5306566953659058}
{"content": "TGF-beta superfamily signaling pathways emerged with the evolution of multicellular animals, suggesting that these pathways contribute to the increased diversity and complexity required for the development and homeostasis of these organisms. In this review we begin by exploring some key developmental and disease processes requiring TGF-beta ligands to underscore the fundamental importance of these pathways before delving into the molecular mechanism of signal transduction, focusing on recent findings. Finally, we discuss how these ligands act as morphogens, how their activity and signaling range is regulated, and how they interact with other signaling pathways to achieve their specific and varied functional roles.", "pred_label": "__label__POS", "pred_score_pos": 0.9998757243156433}
{"content": "The CAP-4 model Apollo Ambient Air Pump supplies oil-free air to low pressure (LP) type-CE supplied-air respirators using a compressed air powered motor. It can supply oil-free breathing air to up to 4 for NIOSH-approved continuous flow hoods or helmet-style respirators approved to operate with 8 cfm at 10 psi or less. The protective cage (frame) shields critical components from damage.\nThe Ambient Air Pump must be placed outside the blast zone in a contaminant-free area to ensure it provides the operator with safe, clean air supply. Potential contaminants include fumes from paints and solvents, exhausts from vehicles and compressors, smoke from burn barrels, and dust from abrasive blasting or other construction activities.\nAdvantages\nSupplies air for up to 4 blast operators wearing type CE helmets or up to 6 operators wearing masks\nEliminates expense of additional breathing air compressor\nEliminates danger of carbon monoxide exposure related to compressor lubricant breakdown\nUses compressed air for power; works where no electric power is available\nNo temperature alarms or additional airline filters required", "pred_label": "__label__POS", "pred_score_pos": 0.5351313352584839}
{"content": "Article Title Abstract\nAchieving independence appears to be a significant concern for education. This is particularly evident in discourses pertaining to art education in England where the aspiration to become independent appears to be synonymous with successful learning. Drawing on disability studies, and more specifically crip theory, this paper offers a Critical crip Discourse Analysis of documents reporting on the quality of art education in England. Here the independent learner emerges as a desirable norm and pupils with special educational needs are made visible through their apparent dependency. As a consequence of this emphasis on independence, dependency is framed as exceptional, undesirable, burdensome and valueless in pedagogic terms. Acknowledging the dominance of independence as a culturally determined fiction frees us to acknowledge problematic depictions of dependency and enable us to create alternative pedagogies that recognize the role of interdependence in learning with and through art.", "pred_label": "__label__POS", "pred_score_pos": 0.8632689118385315}
{"content": "U.S. Home Remodeling trends forecast through 2026\nU.S. home remodeling market is likely to be driven by growing consumer knowledge regarding green buildings and shifting trends towards smart homes. Remodeling of houses generally refers to upgradation of the existing exteriors, interiors, or other improvements to the property such as incorporation of energy saving technology, safety checks and maintenance & repair.\nRising per capita incomes, increasing preference for energy efficient and luxurious living spaces, thriving real estate sector and easy availability of remodeling businesses are factors impacting the regional growth. Moreover, rising cost of land and low lending rates will further fuel the demand for refurbishment across the country. It has been anticipated that the U.S. home remodeling market size will record annual revenues of over USD 500 billion by 2026.\nDifferent programs implemented by the regional governments including residential weatherization, residential retrofit, appliance recycling and direct install programs are encouraging masses to remodel their houses. Growing popularity of mid-century & farmhouse designs has resulted in major changes in American kitchens. Kitchen improvement & additions segment is likely to grow at a significant rate on account of shifting consumer preferences toward streamlined textures, materials and designs.\nA higher demand for ceramic tiles as well as the growing adoption of hardwood flooring will supplement the industry trends. The popularity of luxurious bathroom fittings including wall mounted toilets, rounded rectangle vanity mirrors, floating vanities, and console sink vanities will also offer lucrative opportunities for professionals in the remodeling industry.\nRapidly evolving technology and constant upgrades in roofing technology has gathered a lot of consumer attention. Masses are increasingly becoming aware of environmental protection and energy conservation in households through utilization of green materials. This is prompting more consumers to indulge in home remodeling activities.\nAs per the Joint Center for Housing Studies of Harvard University, around 39% of the nuclear family homes accounted for the overall U.S. rental homes. Spending on home improvements across the U.S. is gradually escalating due to the rising cost of building material and labor. This has prompted homeowners to spend mostly on the existing houses. Prevalent house renting trends will substantially foster home improvement initiatives across the region.\nIn general, a large number of homeowners from states such as Texas, Florida and California possess heavy spending capacities for home renovation projects. According to the NAHB (National Association of Home Builders), the spending per improvement in California had increased to over USD 9,565 in 2018, which was up by 20% when compared to the spending in 2017.\nCompetition in the U.S. home remodeling industry is fragmented due to densely populated areas in different regions. A vital role is being played by the wholesalers for distribution of home improvement products at cost-effective prices. For instance, one of the leading wholesale distributors of home improvement products in the U.S., ABC Supply, introduced a new location in Massachusetts to provide products and solutions and cater to the evolving customer needs in the state.\nThe company has an expanded product portfolio encompassing a range of roofing, doors, windows, siding, railing and decking products. Other prominent providers of home remodeling products and services in the U.S. are Andersen Corporation, Kohler Co., Pella Corporation, Ferguson Enterprises, The Sherwin-Williams Company, ABC Supply, HD supply, US LBM, Beacon roofing supply, and Watsco Inc., among others.", "pred_label": "__label__POS", "pred_score_pos": 0.7017037868499756}
{"content": "Optogenetics is a powerful and rapidly expanding set of techniques that use genetically encoded light sensitive proteins such as opsins. Through the selective expression of these exogenous light-sensitive proteins, researchers gain the ability to modulate neuronal activity, intracellular signaling pathways, or gene expression with spatial, directional, temporal, and cell-type specificity. Optogenetics provides a versatile toolbox and has significantly advanced a variety of neuroscience fields.\nIn this review, using recent epilepsy research as a focal point, we highlight how the specificity, versatility, and continual development of new optogenetic related tools advances our understanding of neuronal circuits and neurological disorders.", "pred_label": "__label__POS", "pred_score_pos": 0.5507450103759766}
{"content": "The toothbrush is one of the most recommended oral cleaning tools to ensure good hygiene. However, it is often difficult to reach the small space between teeth, where food remains accumulate and generate a higher risk of infection.\nAs they contain\nwax and fluorine, these ingredients favour the daily antiseptic action of the hygienic thread. Don't hesitate any longer and get a full mouth cleaning with Lacer's dental floss.", "pred_label": "__label__POS", "pred_score_pos": 0.999915361404419}
{"content": "25.05.2013\nA court in Germany has ruled that drawing consumers’ attention to the price of a product through over-emphasising monthly instalment amounts breaches German competition law. Competition warning letters\nThe case concerned a business which paid for a washing machine advertisement in a newspaper. Various payment methods were advertised, including cash, credit and monthly instalments. The monthly instalment amount was emphasised more than the other methods of payment, which led a competitor to send a warning letter and bring a claim for breach of competition law.\nThe Regional Appeal Court of Jena ruled that emphasising the instalment rate and thus making it more eye catching than other payment methods can infringe German competition law. This is because such pricing strategies infringe the principles of clarity enshrined in § 6a of the Pricing Display Regulations and the duty under § 1 sub-paragraph 6 of the Regulations to ensure the final price is particularly clear.\nBreach of German competition law\nBy over-emphasising the monthly instalment rate, the business had misleadingly drawn consumers’ attention to the advertisement making it more difficult for consumers to compare prices. This amounts to a breach of German competition law.", "pred_label": "__label__POS", "pred_score_pos": 0.7542194128036499}
{"content": "Parliamentary candidates should have a legal right to time off work to campaign, and parties should offer bursaries to would-be MPs from poorer backgrounds, a think tank says. The Institute for Government’s report said Westminster was ‘overwhelmingly white, male and middle-class’. Just one fifth of MPs are women and 27 out of 650 are from ethnic minorities.\nThe report argued that improved selection methods were only part of the answer. ‘The problem is increasingly not overt or covert discrimination within political parties, but the lack of women applying to become candidates in the first place. The same is true for other under-represented groups. Parties need to focus on increasing the supply of aspiring parliamentary candidates by removing some of the barriers to participation, including the high cost and time commitments, which act as a significant deterrent to candidates from non-traditional backgrounds.’ (BBC, 14th November 2011)\nTarmac is a company that has long realized how the business benefits from having a diverse workforce. Its people are recognized as a critical resource: drawing on the widest available pool of talent ensures that Tarmac has the skills and abilities to build and sustain competitive advantage.\nTarmac operates in the heavy buildings materials industry which has traditionally had a workforce of older, male employees. This is changing. Tarmac pursues a strategy of inclusion which is led directly from CEO level. This means it is creating a culture that values the differences between people. This strategy not only enables the company to use people effectively, but its focus on training, supporting and engaging people also helps the company to recruit and retain quality employees. This adds value to the business and contributes to achieving its mission.", "pred_label": "__label__POS", "pred_score_pos": 0.6271926164627075}
{"content": "Problematic Social-Networks-Use in German Children and Adolescents : The Interaction of Need to Belong, Online Self-Regulative Competences, and Age\nAdolescents nowadays spend much time communicating via social networks. Recent investigations also report a noticeable proportion showing a problematic usage behavior, underlining the importance of better understanding its development and maintenance in young individuals. Theoretical views on Internet-use disorders assume that specific predispositions and needs can contribute to addictive behaviors in interaction with further aspects including Internet-related cognitive biases. This study focuses on vulnerable individuals due to their age and investigates interactions between possible risk (need to belong, NTB) and protective factors (online self-regulative competences, OSRC). Participants (N = 466) between 10 and 17 years answered questionnaires assessing social-networks-use disorder symptoms, NTB, and OSRC. Moderated regression analysis revealed significant effects of age, NTB, and OSRC. Three-way interaction was also significant (potentially mainly caused by females), with highest social-networks-use disorder symptoms found for individuals with high NTB and low OSRC, especially when older. With high OSRC, symptoms were significantly lower for both younger and older individuals having high NTB. However, even if NTB was low, older individuals showed high social-networks-use disorder symptoms if their OSRC were low. The results highlight the importance of improving specific competences to prevent problematic usage behaviors, which should be considered in youth-tailored prevention and intervention programs.\nPreview Cite Citation style: Rights Use and reproduction:This work may be used under a\nCreative Commons Attribution 4.0 License (CC BY 4.0)\n.", "pred_label": "__label__POS", "pred_score_pos": 0.6890559196472168}
{"content": "Abstract\nDuring solar eclipses, the Moon's shadow causes a large reduction in atmospheric energy input, including not only the stratosphere but also the thermosphere and ionosphere. The eclipse shadow has a supersonic motion which is theoretically expected to generate atmospheric bow waves, similar to a fast-moving river boat, with waves starting in the lower atmosphere and propagating into the ionosphere. However, previous geographically limited observations have had difficulty detecting these weak waves within the natural background atmospheric variability, and the existence of eclipse-induced ionospheric waves and their evolution in a complex coupling system remain controversial. During the 21 August 2017 eclipse, high fidelity and wide coverage ionospheric observations provided for the first time an oversampled set of eclipse data, using a dense network of Global Navigation Satellite System receivers at ∼2,000 sites in North America. We show the first unambiguous evidence of ionospheric bow waves as electron content disturbances over central/eastern United States, with ∼1 h duration, 300–400 km wavelength and 280 m/s phase speed emanating from and tailing the totality region. We also identify large ionospheric perturbations moving at the supersonic speed of the maximum solar obscuration which are too fast to be associated with known gravity wave or large-scale traveling ionospheric disturbance processes. This study reveals complex interconnections between the Sun, Moon, and Earth's neutral atmosphere and ionosphere and demonstrates persistent coupling processes between different components of the Earth's atmosphere, a topic of significant community interest.\nAll Science Journal Classification (ASJC) codes Geophysics Earth and Planetary Sciences(all)", "pred_label": "__label__POS", "pred_score_pos": 0.9746056795120239}
{"content": "Is the risk of cultural stagnation a valid objection to rejuvenation therapies? You guessed it—nope.\nThis objection can be discussed from both a moral and a practical point of view. This article discusses the matter from a moral standpoint, and concludes it is a morally unacceptable objection. (Bummer, now I’ve spoiled it all for you.)\nHowever, even if the objection can be dismissed on moral grounds, one may still argue that, hey, it may be immoral to let old people die to avoid cultural and social stagnation, but it’s still necessary.\nOne could argue that. But one would be wrong.", "pred_label": "__label__POS", "pred_score_pos": 0.9967026710510254}
{"content": "This course will investigate the dominant critical perspectives that have contributed to the development of Environmental Communication as a field of study. This course explores the premise that the way we communicate powerfully impacts our perceptions of the “natural” world, and that these perceptions shape the way we define our relationships to and within nature.\nThe goal of this course is to access various conceptual frameworks for addressing questions about the relationship between the environment, culture and communication. Students will explore topics such as nature/wildlife tourism, consumerism, representations of the environment in popular culture and environmental activism.", "pred_label": "__label__POS", "pred_score_pos": 0.9296057820320129}
{"content": "Diffusion functions in term-structure models are measures of uncertainty about future price movements and are directly related to the risk associated with holding financial securities. Correct specification of diffusion functions is crucial in pricing options and other derivative securities. In contrast to the standard parametric two-factor models, we propose a non-parametric two-factor term-structure model that […]\nThere currently exists in the literature several continuous-time one-factor models for short-term interest rates. This paper considers a wide range of these models that are nested into one general model. These models are approximated using both a discrete-time model and a model that accounts for aggregation effects over time, and are estimated by both the […]", "pred_label": "__label__POS", "pred_score_pos": 0.5704872608184814}
{"content": "The U.S. Food and Drug Administration approved Eli Lilly's Verzenio (abemaciclib) in combination with an aromatase inhibitor as an initial treatment for postmenopausal women with advanced breast cancer. Verzenio is for breast cancer tumors that are hormone receptor-positive (HR+) and human epidermal growth factor receptor 2-negative (HER2-). This is the third approval Verzenio has received in a five-month period, significantly expanding the drug's treatment scope. The treatment is a dual inhibitor of the cyclin-dependent kinases (CDK) 4 and 6. CDKs regulate cell proliferation and growth, and CDK4/6 specifically are often highly elevated in breast cancer, fueling the uncontrolled proliferation of cancer cells. The FDA's decision was supported by the positive results from the Phase 3 MONARCH trial (NCT02246621), which evaluated whether Verzenio delayed the time until disease progression in postmenopausal women with HR+, HER2- advanced breast cancer and had not had previous systemic therapy. The study enrolled 493 women who were randomized to receive either Verzenio plus an aromatase inhibitor – Arimidex (anastrozole) or Femara (letrozole) – or placebo plus an aromatase inhibitor. Patients treated on a continuous schedule of Verzenio plus an aromatase inhibitor remained free of disease worsening for 28.2 months (2.3 years) compared to 14.8 months (1.2 years) in placebo controls. Among those treated with Verzenio, 54% re", "pred_label": "__label__POS", "pred_score_pos": 0.6238889098167419}
{"content": "Since 2015, the Trudeau government has shown a clear preference for providing Canadians benefits today, financed by debt that imposes costs on the next generation, and a disinterest in targeting assistance to those in need. Given the state of federal finances and their future path, the government must make hard decisions about several programs including the Canada Child Benefit (CCB), one of the Trudeau government’s signature reforms.", "pred_label": "__label__POS", "pred_score_pos": 0.5746601819992065}
{"content": "TAX & ACCOUNTING\nAddressing global trade and indirect tax compliance challenges through technology\nManaging global trade and indirect tax compliance efficiently can be a challenging and demanding process. Key stumbling blocks are the volume, variety and velocity of data involved – not to mention staying up to speed on all the regulatory developments and geopolitical events that impact cross-border trade and tax decisions.\nThis article explores how businesses can:\nManage global trade in an unpredictable environment Stay up-to-date with changing tax reforms Factors impacting burdensome tasks in global trade and tax functions Role of technoloy to simplfy and automate tasks within these functions Complete the form below to receive a free copy today!", "pred_label": "__label__POS", "pred_score_pos": 0.9516984224319458}
{"content": "By Kensi Martinez ’21\nAnyone who knows me can attest to my avid love for Quora, a question-and-answer website where you can find people from the likes of regular high school students to Barack Obama himself. I can spend anywhere from one to eight hours on the site daily, learning personal opinions, facts, and news—and sometimes writing them myself as the fourth-most viewed writer for Pomona College!\nRecently, I stumbled across a question while scrolling through my feed: “Can empathy be developed or is it just a natural trait?” The top answer described a woman’s experience on both sides of being a foreigner, from discriminating against an Indian man for his poor English in a chemical engineering lab to becoming the one discriminated against in Thailand for her poor Thai/Siamese. Having recently returned from my month and a half study abroad program in Korea, I realized that what made me feel so at ease in Korea as a foreigner was that, unlike this (white) woman, I had gone from being a foreigner to being a foreigner. A bit of a funny sentence, isn’t it? Let me unpack it.\nWhile I am a U.S. citizen and was born in Los Angeles, I am of Honduran decent and am a first-generation American. Like the Indian man, there was a time in my life when I struggled to learn English, having only been taught Spanish at home, and a time when my intellect was called into question because of my lack of English-speaking abilities. The most difficult question to answer has always been, “Where are you from?” Most often, people aren’t looking for me to tell them I’m from Los Angeles, but, rather, asking me about my background because my brown skin and 3c curly hair have permanently marked me as a “foreigner” in my own country.\nWhile it is obvious how I was marked as a foreigner in Korea, even there, I was often labeled by Koreans as “Latina” or “Mexican,” not “American.” However, the most interesting thing I discovered was the stereotypes Koreans had about Latina women were similar to those I experienced in America. During a whole-day tour of Seoul, I had the opportunity to talk in-depth with three Korean university students, each studying at different prestigious universities in Korea. One of the things we briefly discussed was their insights on non-white foreigners. At the time of my asking, we had already shared a meal and gone to a 노래방 (\nnoraebang, Korean-style karaoke in a private room), so the mood was light and comfortable. They answered me honestly, admitting that there was a preference in Korea for white foreigners, and the two men in the group elaborated on the highly sexualized image of Latina women in Korea. Similar to the stereotype in the U.S., Latina women were viewed as promiscuous and “easy.” Essentially, nothing had changed: I had gone from being a foreigner to being a foreigner.\nP.S.: I really did love my stay in Korea—this blog post only showcases one side of my experiences in Korea. I’ll write about the many cultural excursions I took and what I learned in my next blog post!", "pred_label": "__label__POS", "pred_score_pos": 0.6853858232498169}
{"content": "According to the Fifth Assessment Report (AR5) of the Intergovernmental Panel on Climate Change (IPCC), the impacts of climate change are increasing globally.\nThe report of the Working Group II (WGII) highlights disruption in the global hydrological cycle due to changing precipitation patterns and melting of snow and ice causing proximate effects such as extreme weather conditions, droughts and flooding.2 A significant shift in ecosystems, leading to shifts in range, migration patterns, seasonal activities and abundance of territorial and marine species, affecting the livelihood of resource-dependent communities, was reported.3 Added threats to food security of poor populations, human health, lives of communities in low-lying coastal zones and infrastructure damage were projected in the report. More than 528,000 people died as a direct result of nearly 11,000 extreme weather events in 1996–2015 and losses amounted to around US $3.08 trillion.", "pred_label": "__label__POS", "pred_score_pos": 0.7900975942611694}
{"content": "2017 Volume 16 Issue 1 Pages 100-115\nThe purpose of this study was to examine ways of building and maintaining a positive organizational climate by describing an actual situation. We focused on a ward that had a positive organizational climate in the 1970s. The study’s participants included a chief nurse and two staff nurses who had worked on the same ward. Narratives were gathered through a group interview. The data were analyzed based on four frameworks based on the results of quantitative studies. The results suggest that the chief nurse's sense of control was built on the ideal of a deep consideration for patients, the activities that led to achieving this ideal, and the positive feedback it created. The chief nurse’s sense of control was increased by fostering these characteristics in others. The staff nurses’ sense of control was enhanced by modeling the chief nurse’s behavior. Intimacy among the staff developed through “enough information exchange” and “emotional exchange without reservation.” The sense of control and intimacy among the staff nurses increased morale and improved the atmosphere of the ward.", "pred_label": "__label__POS", "pred_score_pos": 0.7924831509590149}
{"content": "Using a consumer’s testimonial in an advertising campaign requires their prior approval and, in certain cases, obtaining a permit from the UDA.\nIn Quebec, certain competitions must be registered with the Régie des alcools, des courses et des jeux.\nCertain industries are regulated by standards specific to them. For instance, specific rules apply to advertising in the banking, pharmaceutical, automotive and food industries.\nReproducing the images of certain public buildings in an ad requires obtaining authorization beforehand.", "pred_label": "__label__POS", "pred_score_pos": 0.9787121415138245}
{"content": "►▼Show Figures\nThe kidneys play key roles in the maintenance of homeostasis, including fluid balance, blood filtration, erythropoiesis and hormone production. Disease-driven perturbation of renal function therefore has profound pathological effects, and chronic kidney disease is a leading cause of morbidity and mortality worldwide. Successive annual increases in global chronic kidney disease patient numbers in part reflect upward trends for predisposing factors, including diabetes, obesity, hypertension, cardiovascular disease and population age. Each kidney typically possesses more than one million functional units called nephrons, and each nephron is divided into several discrete domains with distinct cellular and functional characteristics. A number of recent analyses have suggested that signaling between these nephron regions may be mediated by microRNAs. For this to be the case, several conditions must be fulfilled: (i) microRNAs must be released by upstream cells into the ultrafiltrate; (ii) these microRNAs must be packaged protectively to reach downstream cells intact; (iii) these packaged microRNAs must be taken up by downstream recipient cells without functional inhibition. This review will examine the evidence for each of these hypotheses and discuss the possibility that this signaling process might mediate pathological effects.View Full-Text\nThis is an open access article distributed under the Creative Commons Attribution License\nwhich permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited", "pred_label": "__label__POS", "pred_score_pos": 0.6469539403915405}
{"content": "Enhance agility through a structured but flexible service, managed by experts.\nLeverage our expertise to minimise risk\nOrganisations of all sizes are shifting to the Public Cloud with large enterprises being the early adopters. IDC expects a 5-10%pa swing from traditional infrastructure spend to Cloud infrastructure. While according to Gartner, 28% of spending in key IT segments will shift to the Cloud by 2022.\nNEC’s Managed Public Cloud service helps Government and enterprise organisations that have moved or are considering moving their systems (workloads) into the Cloud by managing the Cloud environment using a structured but flexible service offering. We provide day to day management of individual workloads as well as overarching common services such as DNS and load balancing. Our service can minimise risk and free up staff in your organisation to work on strategic ICT projects.\nAround the clock service Managed by experts Single point of contact Reduced costs Cloud neutral Scalable Why NEC?\nNEC is a safe pair of hands with a strong heritage of managing and deploying critical services and applications. We can manage existing infrastructure and public Cloud workloads to support customer’s journey to Cloud and hybrid environments.\nWe believe in offering our customers the right advice and are not incentivised by Cloud providers to move workloads regardless of whether they are suitable for the Cloud or not.\nNEC have a strong local presence with flexible support models (onshore, offshore or blended), combined with a global network of 303 group companies with a combined revenue of US$26B.", "pred_label": "__label__POS", "pred_score_pos": 0.6138253211975098}
{"content": "Computational analysis of the productivity potential of CAM. Shameer S., Baghalian K., Cheung CYM., Ratcliffe RG., Sweetlove LJ.\nThere is considerable interest in transferring crassulacean acid metabolism (CAM) to C3 crops to improve their water-use efficiency. However, because the CAM biochemical cycle is energetically costly, it is unclear what impact this would have on yield. Using diel flux balance analysis of the CAM and C3 leaf metabolic networks, we show that energy consumption is three-fold higher in CAM at night. However, this additional cost of CAM can be entirely offset by the carbon-concentrating effect of malate decarboxylation behind closed stomata during the day. Depending on the resultant rates of the carboxylase and oxygenase activities of rubisco, the productivity of the PEPCK-CAM subtype is 74-100% of the C3 network. We conclude that CAM does not impose a significant productivity penalty and that engineering CAM into C3 crops is likely to lead to a major increase in water-use efficiency without substantially affecting yield.", "pred_label": "__label__POS", "pred_score_pos": 0.860182523727417}
{"content": "In a bid to contain the spread of COVID-19, the Thai government announced today they will impose a range of new measures, designed to tighten the quarantine controls already in place. These strategies include blocking all travel into Thailand – for both foreigners and Thai nationals – and imposing a curfew.\nThe news wasconfirmed by Prime Minister Prayut Chan-o-cha, speaking at the Covid-19Situation Administration Centre today. In a statement to the assembled press, he announced a nationwide curfewbetween the hours of 10pm until 4am, starting from tomorrow (3\nrdApril).\nNo-one will be permitted to go outside during these hours, except for medical professionals and patients, or those transporting essential goods or working in sanctioned services. Anyone violating the terms of the curfew could face up to two years in prison and/or a fine of as much as THB40,000 (US$1,200), according to Article 18 of the Emergency Decree.\nThailand hasalready imposed a temporary banon foreigners entering the country, in effect until 30\nth April.The latest measures, which are scheduled to last for at least two weeks, expandthese restrictions to include Thai nationals returning home. The governmentexplains the extra step as necessary to prepare “state quarantine”facilities following local patients’ infections being linked to imported casesof the virus.\n“Related agencies will in the meantime prepare the places and coordinate with Thai embassies to ensure all Thais returning home will be quarantined and get proper medical checks,” said the Prime Minister.\nLike the curfew,the new arrival restrictions will come into effect from tomorrow (3\nrdApril) and will continue until 15 th April. The new rules will applyto all new applications for entry to the Kingdom; those already approved forentry will be allowed in, though may have to complete a two-week period ofquarantine. Officials have advised all Thai people affected by the measures tocontact the Thai embassies in their current location and followed the relevantinstructions.\nPreviously, Thais returning home by air had to present a fit-to-fly certificate, along with letters from their embassy confirming they are Thai nationals. Until recently, entry requirements for foreign travellers had included a recent health certificate, along with a health insurance policy amounting to USD100,000 and covering COVID-19 infection. It is not yet clear whether the Kingdom will revert to these arrangements following completion of the temporary ban in April.\nPanorama Destination will continue monitoring the situation in Thailand, and will provide updates as soon as new developments arise. For all the latest news regarding COVID-19 in Thailand, Indonesia, Malaysia and Vietnam, we recommend following our social media channels:", "pred_label": "__label__POS", "pred_score_pos": 0.8078643083572388}
{"content": "Columns/BlogsFeaturesHealth & SafetyManaging/Leadership C-suite leadership is the nagging gap in prevention\nBy Maureen Shaw\nDuring COVID-19, the role of a CEO is more important than ever\nBy Maureen Shaw\nWe are currently living in a different reality.\nOver the past three months, global citizens have endured a period of massive upheaval and change unlike anything seen since the Second World War.\nThe COVID-19 pandemic has resulted in a seismic shift in how we live, work and play. Even after the pandemic is ultimately addressed, it is unlikely we will return to what we previously thought of as normal — certainly not soon.\nBut a new, even better, future could emerge — if leaders step up.\nThe Association of Workers’ Compensation Boards of Canada (AWCBC) tells us that 1,027 workplace fatalities were recorded in Canada in 2018, an increase of 76 lives lost over the previous year. Among these deaths were 27 young workers aged 15 to 24.\nAWCBC also recorded 264,438 accepted claims (an increase from 251,508 the previous year) for lost time due to a work-related injury or disease, including 33,058 from workers aged 15 to 24.\nWhile OH&S professionals have expressed concerns over these persistently rising statistics, the bottom-line question is: What is truly preventing the meaningful reduction or potential elimination of these needless deaths and injuries?\nSome might suggest a reported reduction in the number of accepted claims is evidence of declining injury rates. In fact, there are many reasons accepted claims are down, but that trend is not solely a result of injuries and illness elimination. That’s another story!\nCOVID-19 driving discussion\nWe are working to manage the impacts of COVID-19 by having the right policies, procedures and support in place for all our workers and our communities.\nAt the same time, we need to ensure we keep the focus on core health and safety by having an effective health and safety management system in place.\nWhile some organizations and their leaders are doing an excellent job, historically a lack of senior-level leadership and support for health and safety in organizations has created a critical gap that sadly persists today.\nGiven some of the questions, concerns and outcomes, leadership from the top — the C-suite — is imperative. Simply delegating responsibilities to OH&S professionals, managers, supervisors and workers is not leadership.\nWhile having an effective joint health and safety committee is critical — and all levels of a workforce must be part of the process — trusted, active, resilient, caring, agile leadership is vital, especially in light of current and future events.\nIn some parts of our country there are evident gaps in co-ordination amongst public organizations responsible for health and safety. In addition to providing much-needed guidance on COVID-19 health and safety practices, these organizations should also support businesses by working with them to develop clear guidelines, products and services — and share them broadly.\nAddressing the COVID-19 pandemic’s impacts on workplaces demands this kind of guidance and support. It also provides a rich opportunity for leadership engagement.\nCEOs, executives set the tone\nTransformative senior-executive leadership is needed now, more than ever. A lack of leadership will continue to see businesses lost, alongside a continuing increase in the number of ill and injured workers.\nCEOs and executives are responsible for setting the tone, creating the values and maintaining a healthy workplace culture. They have the sphere of influence to ensure health and safety is integral and embedded into operations. Ensuring health and safety messages are consistently communicated firmly, with empathy and understanding, is urgent.\nHealth and safety professionals understand the hierarchy of controls. The upside-down pyramid that moves from top to bottom: elimination – substitution – engineering controls – administrative controls – PPE.\nAt the very top should be leadership from the CEO and executive team. The effectiveness of the hierarchy is dependent on leadership being strong, committed and consistent.\nHealth and safety concerns have never been higher in the minds of people as they are now. Carefully and properly implemented, measures to protect health and safety provide the opportunity to emphasize injury and illness prevention in our workplaces and our communities.\nThose at the top of organizations must lead, inspire, and empower.\nNow is the time to bridge the nagging leadership gap and truly foster a healthier and safer future for all workplaces and communities in Canada.\nMaureen Shaw is the former president and CEO of the Industrial Accident Prevention Association. She lives in Victoria.", "pred_label": "__label__POS", "pred_score_pos": 0.5852648615837097}
{"content": "The entire Transposit team — DevOps Cat included — is thrilled to sponsor and virtually attend Gremlin’s Chaos Conf, the World’s Largest Chaos Engineering event, this upcoming Tuesday - Thursday, October 6 - 8!\nChaos engineering plays an integral role in incident management. Similar to the crash tests car companies use to test safety, this process enables teams to “stress test” systems and increase their reliability. However, the dependability of your systems is also contingent upon the experiences of your team. This is why the best runbooks take those experiences and turn them into shared knowledge. Chaos engineering can and should be a key component to preparing for outages before they happen — by ensuring your runbooks are accurate, up-to-date, and useful when an incident does occur.\nWe’re also excited to serve as a Diversity & Inclusion sponsor for the event. As a growing organization, we know that a thoughtful and purposeful approach to diversity, equity, inclusion, and belonging — both within our organization as well as the broader Tech community — enables us all to keep the human experience top of mind. One of Transposit's core tenets is that the human operator is an inextricable element of a working system, just as they are to the culture and success of an organization and its products.\nAt Gremlin’s Failover Conference this past spring our community engineer, Taylor Barnett, spoke about human-in-the-loop automation and how it serves as a complement to increasing automation more sustainably into your stack. We had so much fun interacting with speakers and attendees, especially through a series of comics that ultimately served as DevOps Cat’s Conference debut. We can’t wait to descend into Chaos Conf — and share more of Yoko's newest DevOps Cat comic (pictured) — next week! Let us know @transposit if you will be there too so we can connect!", "pred_label": "__label__POS", "pred_score_pos": 0.5537234544754028}
{"content": "FOR IMMEDIATE RELEASE: March 5, 2012\nContact:\nBrian Concannon, Jr., Esq., Institute for Justice & Democracy in Haiti, brian@ijdh.org, +1-541-263 0029 (English, French, Creole) Mario Joseph, Av., Bureau des Avocats Internationaux, (in Haiti), mario@ijdh.org, +509 3701-9878 (French, Creole, English)\nMonday, March 5, 2012\nBoston, Port-au-Prince--In a statement to the United Nations (UN) Security Council last week, U.S. Permanent Representative Susan Rice stressed the importance of UN accountability for its role in bringing cholera to Haiti, calling on the UN to \"redouble its efforts to prevent any further incidents of this kind and to ensure that those responsible are held accountable.\"\nThe UN has not accepted responsibility for the outbreak despite extensive evidence, including by the UN's own panel of experts, that cholera was brought to Haiti by troops from the UN peace-keeping mission in Haiti (MINUSTAH), and introduced into Haiti's largest river system through negligent waste disposal practices. The epidemic has killed over 7,000 Haitians and sickened over 500,000 since October 2010. It is expected to worsen as the rainy season begins.\n\"The UN ignored warnings about the lethal impact that cholera would have in Haiti, and allowed human waste from its base to poison Haiti's central river. The UN must now accept responsibility for the deaths it has caused,\" said Mario Joseph, Managing Attorney of the Bureau des Avocats Internationaux (BAI). The BAI represents over 5,000 victims of cholera who filed claims with the UN, seeking nationwide investments in water and sanitation infrastructure, compensation for the individual victims, and a public apology.\n\"We welcome the statement by Ambassador Rice, and consider this an important step in the right direction,\" said Brian Concannon Jr., Director of the Institute for Justice & Democracy in Haiti, co-counsel on the claims. \"It is time for the UN to embrace accountability for its actions, and stop the cholera's killing.\"\nThe statement by Ambassador Rice comes after a Security Council visit to Haiti February 13 through 16 to evaluate MINUSTAH's operations. Hundreds of Haitians joined in peaceful demonstrations during the Security Council delegation's visit to protest MINUSTAH's lack of responsibility for the cholera outbreak and recent allegations of sexual abuse by UN soldiers.\nThe lack of accountability has led to widespread discontent with MINUSTAH. A majority of Haitians surveyed in a recent study reported that they had overall negative views of MINUSTAH, and nearly three quarters of the respondents (74.5%) believed that MINUSTAH owes some form of restitution to cholera victims.", "pred_label": "__label__POS", "pred_score_pos": 0.5557156801223755}
{"content": "페이지 정보작성자 최고관리자댓글 0건조회 8회 작성일 20-11-17 18:34 본문 AMSA prohibited ship from leaving until nine crew were repatriated Nine seafarers, two of whom had been onboard the Panama-flagged cargo ship Brio Faith for 20 months with no leave, are now making their way home, after intervention by the Australian Maritime Safety Authority (AMSA).\nSeafarers | 05/11/20\nAMSA issued a direction notice, prohibiting the ship from departing until all nine seafarers had been repatriated.\nSpecifically, the Authority inspected the ship in Port Alma, Queensland on 2 November, where inspectors verified that three crew had been onboard for over 12 months, four crew had been onboard for over 16 months and two crew had been onboard for over 20 months.\nDuring the inspection, the operator Tianjin Shun Xin Yuan Shipping Co LTD assured AMSA, and provided evidence, that crew would be repatriated the following day.\nOn 3 November, the operator informed AMSA that those repatriation plans had fallen through. The owners requested that the seafarers remain onboard until the next port, Shanghai.\nAMSA did not accept this proposal due to the length of time the seafarers had already spent at sea and prohibited the ship from departing unless repatriation would take place immediately.\nAs a result, those nine seafarers are now making their way to Brisbane, where they will embark international flights home to their families.\nEventually, the ship embarked fresh crew to meet its minimum manning requirements and departed on Wednesday evening, 4 November.\nIt should be every operator’s and owner’s highest priority to ensure the welfare of their seafarers, and safety of their operations is maintained. 20 months onboard with no leave is completely unacceptable and will lead to increased risk of accidents,\n...stated AMSA Operations North Manager Greg Witherall, with respect to this incident.\nThe incident comes amid a growing discussion across the industry, concerning a 'humanitarian crisis' which has left thousands of seafarers trapped onboard beyond acceptable limits, due to travel restrictions.\nWe will continue to enforce the Maritime Labour Convention, look after seafarers and ensure the safety of shipping.", "pred_label": "__label__POS", "pred_score_pos": 0.9899101257324219}
{"content": "Inflammatory bowel disease is often associated with hematologic abnormalities such as anemia, leukocytosis, and thrombocytosis. We report for the first time an unusual case of ulcerative colitis complicated by thrombotic thrombocytopenic purpura. Severe lower gastrointestinal bleeding resolved with subtotal colectomy, but the thrombotic thrombocytopenic purpura proved unresponsive to medical treatment. Splenectomy and completion proctectomy were performed, ultimately resulting in a successful outcome.", "pred_label": "__label__POS", "pred_score_pos": 0.9652814269065857}
{"content": "We are committed to supporting people from culturally and linguistically diverse backgrounds to increase their capacity to build stronger relationships within the family. Through various services Relationships Australia WA aims to enhance the lives of these individuals, increasing their ability to contribute to the community and this in turn greatly aids the settlement process.\nAt this stressful time, many people across Australia’s migrant communities are facing challenges because of COVID-19. Different regions of Australia and different communities within regions will have different challenges.\nWe welcome and value the contributions to our society made by our multicultural community. As a trusted leading provider of family and relationships services for over 70 years, Relationships Australia WA is proud to stand beside all community members, in all of their diversity, to support them to maintain positive and safe relationships.\nRelationships Australia WA celebrates the strength of our diverse communities, and acknowledges and respects the cultural, spiritual and economic sovereignty of Aboriginal and Torres Strait Islander people as the traditional custodians of the land on which we all live.\nRelationships Australia WA is a signatory to Relationships Australia's \"Framework For Action\" which underpins our national commitment to Aboriginal and Torres Strait Islander Peoples. This commitment is outlined by our Statement Of Service.", "pred_label": "__label__POS", "pred_score_pos": 0.8703944087028503}
{"content": "Abstract\nOrally administered phages to control zoonotic pathogens face important challenges, mainly related to the hostile conditions found in the gastrointestinal tract (GIT). These include temperature, salinity and primarily pH, which is exceptionally low in certain compartments. Phage survival under these conditions can be jeopardized and undermine treatment. Strategies like encapsulation have been attempted with relative success, but are typically complex and require several optimization steps. Here we report a simple and efficient alternative, consisting in the genetic engineering of phages to display lipids on their surfaces. Escherichia coli phage T7 was used as a model and the E. coli PhoE signal peptide was genetically fused to its major capsid protein (10 A), enabling phospholipid attachment to the phage capsid. The presence of phospholipids on the mutant phages was confirmed by High Performance Thin Layer Chromatography, Dynamic Light Scattering and phospholipase assays. The stability of phages was analysed in simulated GIT conditions, demonstrating improved stability of the mutant phages with survival rates 102-107 pfu.mL-1 higher than wild-type phages. Our work demonstrates that phage engineering can be a good strategy to improve phage tolerance to GIT conditions, having promising application for oral administration in veterinary medicine.", "pred_label": "__label__POS", "pred_score_pos": 0.5160589814186096}
{"content": "Abstract\nSeveral species of tetranychid mites including Tetranychus urticae Koch (Acari: Tetranychidae) construct complicated three-dimensional webs on plant leaves. These webs provide protection against biotic and abiotic stress. As producing web is likely to entail a cost, mites that arrive on a leaf with web are expected to refrain from producing it, because they will gain the benefit of protection from the existing web. Mites that produce less web may then allocate resources that are not spent on web construction to other fitness-enhancing activities, such as laying eggs. To test this, the oviposition rate of T. urticae adult females was examined on leaves with web. As a control, we used leaves where the web had been removed, hence both types of leaves had been exposed to conspecifics previously and were thus damaged. On leaves with web, the oviposition rate of T. urticae females was higher than on leaves where the web had been removed. Therefore, the presence of web constructed by conspecifics enhanced the oviposition rate of T. urticae females. This provides indirect evidence that mites use the web constructed by conspecifics and thereby save resources that can be allocated to other traits that enhance reproductive success\nKeywords womersleyi schicha acari predatory mite spinning behavior phytophagous mite plant phytoseiidae aggregation kanzawai eggs avoidance", "pred_label": "__label__POS", "pred_score_pos": 0.9136185646057129}
{"content": "Global regulatory legislation is a headache for almost every business, especially large,multi-national corporations. Organizations operating across borders must manage diverse regulations specific to each country. Today, we see an evolution of data privacy-specific laws to formalize, unify and strengthen data protection. Businesses not in compliance with various data privacy regulations face stiff regulatory fines.\nModern data privacy laws started in 2018 when the European Union (EU) implemented the General Data Protection Regulation (GDPR). GDPR affects hundreds of thousands of businesses globally. EU regulation imposes strict data privacy rules. Specifically, regarding who has control and access to digital assets, defining the protection and use of data of European citizens. To date, the EU has issued 340 GDPR fines totaling €158 million.\nIn the United States, different states and jurisdictions have various data privacy laws. For example, as of January 1, 2020, California enforces the California Consumer Privacy Act (CCPA). The legislation enhances privacy rights and consumer protection for California residents. What these data privacy regulations have in common is they relate to location, access and usage of personal information. The combination of strict data security standards makes it difficult to advance digital business initiatives while avoiding regulatory penalties. Businesses must take a practical approach to meet data privacy requirements.\nManaging Complex Privacy Regulations\nControlling access to digital assets is a reoccurring theme regarding managing data privacy laws. As a result, organizations require a multidimensional security model to enforce complex and evolving privacy regulations.\nModern access control technologies like dynamic authorization can navigate compliance. By utilizing an Attribute Based Access Control (ABAC) model, dynamic authorization provides fine-grained access control leveraging a policy based approach. With ABAC, policies are based on the relationships between user attributes. Attributes define who, what, when, where, how and why a user is granted or denied access to a data set.\nDynamic authorization delivers flexible data protection capabilities required to ensure only authorized users receive access to regulated information.\nDynamic Authorization Protects Information and Streamlines Compliance\nData protection has different definitions, depending on the legislation. However, both GDPR and CCPA identify similar requirements companies must follow. Both laws require strict access control methods, the disclosure of personal information collected and the purpose of processing that data. Additionally, the regulations demand businesses give consumers access to their personal data or request that their personal information is deleted. Dynamic authorization supports the data access, data transparency and user consent requirements involved with GDPR and CCPA. ABAC policies provide a contextual and data driven access control relationship, leveraging a precise set of policies and attributes to decide who receives access to sensitive data within an organization. Dynamic authorization enforces precise policies that expose regulated data only to authorized end users, with the ability to mask data\nand govern the specific actions users can take.\nBy leveraging the full capabilities of dynamic authorization, consumer data is protected. In addition, the same ABAC policies extend according to the consumer’s discretion. ABAC capabilities not only protect data against unauthorized access to the information within a company, but they also allow customers to view and correct data. Consequently, users outside the business can also manage their information and grant consent to use or sell data to third-parties.\nDynamic authorization can help large, global enterprises manage complex global data privacy regulations like GDPR and CCPA. By providing a centralized, fine grained policy based approach to access control, organizations ensure compliance and avoid hefty regulatory fines.", "pred_label": "__label__POS", "pred_score_pos": 0.5510847568511963}
{"content": "Bastion Balance Korea Review Bastion Balance, Seoul Korea Overview Headquarters:Seoul, S. Korea Contact Number:+822 3478 4248 Office Email:info@bastionbalance.com.com Social Media Links:Facebook, LinkedIn Official website:https://bastionbalance.com\nBastion Balance is a financial institution specializing in wealth management.\nThe company is mainly located in Seoul, Korea.\nIt can, however, affiliate itself with clients from all over the world.\nFor years in the industry, they have been deemed outstanding; they have received global recognition for its astounding success in providing services to clients, especially in asset management.\nThey have been tightly holding a good reputation of being responsive to clients by incorporating their interests into their assets while at the same time prioritizing their welfare with extra care.\nThey offer services for financial growth with credibility and trustworthiness, nurturing their private wealth, and providing financial security.\nHolistic wealth management can be guaranteed.\nServices included are financial planning, portfolio management, retirement and estate planning, and tax sheltering strategies.\nThis institution focuses on global business-related functions like professional experience, technology, and personal relationships.\nFinancial assistance\nWealth and asset management are vital terminology in the business industry.\nIt systematically manages both tangible and intangible receipts.\nBastion Balance Korea promotes its expertise in delivering great wealth and asset management.\nIf you need financial assistance and concerns regarding business problems, they offer resolutions for it.\nThey have assured outstanding customer service across the globe.\nMoreover, they have 89 investors worldwide to trust them and have handled 1.78 million client assets.\nwealth management plans\nTheir wealth management plans are ideal for various individuals, families, and corporations, whether locally or internationally.\nAs clients apply for an investment, their goals will be ensured to match their individual or respective goals.\nSince they acclaim to prioritize the client’s financial well-being, they have recognized the typical difficulties and circumstances that might occur.\nInterestingly, with your goals articulated, a Bastion Balance Korea advisor will be there all throughout for guidance in the wealth management plan.\nThe advisor will then trace the safest and most considerable path to attain your goals successfully.\nWith their supervision, the establishment asset allocation parameters will be made along with the specific investments necessary to reach those parameters.\nEverything will be monitored with effective portfolio management, including the volatility of financial markets and communicated thoroughly to ensure your stability and stagnant growth.\nFrom then, you will be able to easily navigate the predictable financial periods you will encounter and your adaptability to change.\nRest assured, risks and tolerance will be recognized and dealt with accordingly.\nIt is impressive how proactive they are with the clients’ investment plans.\nLots of considerations must be determined to give the most accurate response in addressing this plan.\nThey will be looking at your growth rate, risk tolerance and its appropriateness, liquidity concerns, accessibility of funds, and the like.\nBy providing your insights regarding this, recommendations from extensive assets that have been examined profoundly by their research department will be given.\nBastion Balance Korea has been perceived as an expert in handling wealth assets.\nThey believe that being knowledgeable in wealth and asset management has an immense impact on the business and finance industry.\nAdvisors see the importance and advantages of maintaining a good asset and wealth management.\nIt can cause a significant gap in the industry.\nThe process of asset management is done thoroughly by financial advisors.\nThis communal process involves overseeing investments to ensure efficient financial safety and assets management.\nThe company delivers long-term progress and regularly does reviews to keep your investment on track, keeping them consistent with your life and set goals.\nAs the world continues to welcome technological advancements, financial institutions ensure their adaptability touches this technical emergence.\nBastion Balance Korea adapted to these changes.\nThey have anticipated the necessity to develop their services to meet the clients’ demands; thus, presenting digital exploration where clients can access their services online.\nThey established a smart and efficient website, carefully programmed and organized for easy navigation.\nThrough this, clients who are too busy to visit physical branches can see this beneficial, for they can access it anywhere and anytime.\nThis alternative proves how the organization values its clients’ satisfaction.\nOverall\nBastion Balance proves the recognition they have received and living the identity they promote.\nGiven the outstanding reputation, their services are smart and well-rounded.\nClients will find it ensuring enough to trust their wealth and asset management.\nBastion Balance Korea FAQ What services does Bastion Balance provide?\nBastion Balance provides holistic wealth management. This can include financial planning, portfolio management, retirement and estate planning, and tax sheltering strategies.\nWhere are Bastion Balance clients located?\nWe work with clients from all over the world. We leverage technology to ensure seamless communication.\nAre my investment returns guaranteed?\nNo. We mark long-term progress against historical results, and do regular reviews to ensure investment goals are consistent with your life, and investments are meeting your needs.\nDoes Bastion Balance provide discretionary account management services?\nYes. Discretionary accounts are available to clients with minimum US$500,000 assets under management, or family accounts combined to US$1,000,000.", "pred_label": "__label__POS", "pred_score_pos": 0.700087308883667}
{"content": "Tackling tax avoidance and evasion is key to ensure that everyone pays their fair share of tax.\nWorking with the OECD, the EU Commission and other EU member states, the UK government has introduced the Directive on Administrative Cooperation (DAC6) which aims to identify potentially aggressive tax arrangements by further increasing reporting transparency.\nWhat is DAC6?\nDAC6 introduces a requirement for tax intermediaries and advisers to provide tax authorities with details of certain international tax planning arrangements. Where the arrangements fall within certain 'hallmarks' mentioned in the directive and in circumstances where the intended benefit of the arrangement is a tax advantage.\nIn certain instances the obligation to report falls on the taxpayer and information reported will be shared between tax authorities. There are no de-minimis limits and penalties for failures can be significant, with local country penalties in the range of several million Euros.\nEU member states were required to incorporate DAC6 into their domestic law by 31 December 2019. Under the Directive, reporting starts after July 2020 for arrangements dating from 25 June 2018. On 8 May 2020 the EU Commission proposed a delay of up to three months in the commencement of reporting, due to the disruption caused by coronavirus.\nRSM can help you navigate DAC6 and prepare you for the upcoming changes. Download our guide to understand the reporting requirements and how international transactions and arrangements must be reported to tax authorities in future.", "pred_label": "__label__POS", "pred_score_pos": 0.9396628737449646}
{"content": "Uncertain economic environment, aggressive competition, growing influence of digitization and drastically shifting industry landscape characterize the real estate market today. To survive and thrive in this tough marketspace industry players are increasingly focusing and relying on the impact of their marketing efforts. Your marketing campaigns must deliver optimum return on investment (ROI) and its success relies on the speed and quality.\nHowever, plethora of marketing tools that are widely available and continuously evolving customer expectations can be overwhelming, making it difficult to optimize marketing activities. While you may have a great marketing strategy, getting from concept to completion is a challenging process given the tedious and enormous tasks involved. This often restricts your ability to realize your marketing objectives and drive desired sales outcomes.", "pred_label": "__label__POS", "pred_score_pos": 0.9994713068008423}
{"content": "Private capital investment is a critical component of the global innovation ecosystem. Canada offers private investors a strong regulatory banking framework, welcoming immigration policy, ease of starting a business, political stability, protection of minority investors, and low business costs for R&D-intensive sectors.\nVancouver – with its thriving tech sector and startup ecosystem – is a key gateway into investing in Canada’s innovation economy. Furthermore, its proximity to Silicon Valley and major tech hubs along the rest of the Cascadia Innovation Corridor, and to prominent financial centres in the Asia Pacific, connects Vancouver startups and investors alike to global markets.\nAmerican investors collectively account for the greatest share of private capital in Vancouver’s innovation economy. This guide seeks to streamline the investment process by collating the legal and tax considerations necessary for cross-border investment. While this resource focuses on Canadian and American examples, all other international investors are equally likely to benefit from this guide.\nLooking for a printer-friendly version? Try this.\nIn the wake of COVID-19, the Government of Canada and Province of British Columbia took historic measures to support the economy, including multiple stimulus programs.\nAdditionally, the Business Development Bank of Canada (BDC) has announced numerous measures to support Canadian business through the\nBusiness Credit Availability Program.\nNotably for investors, the\nBDC Capital Bridge Financing Program may match – with a convertible note – financing for eligible Canadian startups. A qualified investor must have a fund size of CA$10 million and invested in three Canadian companies. They must also have third-party limited partners and at least one institutional investor.\nAre you a US investor interested in organizing an event on cross-border investment for your angel group or other investor networks? The Vancouver Economic Commission has hosted dedicated events with Deloitte and Fasken featuring panel discussions and moderated Q&A sessions with the writers of the guide.\nThis guide was developed through in-house research and expertise leveraging data from Pitchbook and related sources, with taxation and legal expertise from Deloitte and Fasken.", "pred_label": "__label__POS", "pred_score_pos": 0.9827263951301575}
{"content": "Please use this identifier to cite or link to this item:\nhttps://apo.ansto.gov.au/dspace/handle/10238/8078\nFull metadata record\nDC Field Value Language dc.contributor.author Zhang, Y - dc.contributor.author Mahowald, N - dc.contributor.author Scanza, RA - dc.contributor.author Journet, E - dc.contributor.author Desboeufs, K - dc.contributor.author Albani, S - dc.contributor.author Kok, JF - dc.contributor.author Zhuang, G - dc.contributor.author Chen, Y - dc.contributor.author Cohen, DD - dc.contributor.author Paytan, A - dc.contributor.author Patey, MD - dc.contributor.author Achterberg, EP - dc.contributor.author Engelbrecht, JP - dc.contributor.author Fomba, KW - dc.date.accessioned 2016-11-14T05:29:26Z - dc.date.available 2016-11-14T05:29:26Z - dc.date.issued 2015-10-12 - dc.identifier.citation Zhang, Y., Mahowald, N., Scanza, R. A,, Journet, E., Desboeufs, K., Albani, S., Kok, J. F., Zhuang, G., Chen, Y., Chohen D. D., Paytan, A., Patey, M. D., Archterberg, E. P., Englebrecht, J. P., & Fomba, K. W. (2014). Modeling the global emission, transport and deposition of trace elements associated with mineral dust. Biogeosciences Discuss., 11(12), 17491-17541. doi:10.5194/bgd-11-17491-2014 en_AU dc.identifier.govdoc 7621 - dc.identifier.issn 1726-4170 - dc.identifier.uri http://dx.doi.org/10.5194/bgd-11-17491-2014 en_AU dc.identifier.uri http://apo.ansto.gov.au/dspace/handle/10238/8078 - dc.description.abstract Trace element deposition from desert dust has important impacts on ocean primary productivity, the quantification of which could be useful in determining the magnitude and sign of the biogeochemical feedback on radiative forcing. However, the impact of elemental deposition to remote ocean regions is not well understood and is not currently included in global climate models. In this study, emission inventories for eight lements primarily of soil origin, Mg, P, Ca, Mn, Fe, K, Al, and Si are determined based on a global mineral data set and a soil data set. The resulting elemental fractions are used to drive the desert dust model in the Community Earth System Model (CESM) in order to simulate the elemental concentrations of atmospheric dust. Spatial variability of mineral dust elemental fractions is evident on a global scale, particularly for Ca. Simulations of global variations in the Ca = Al ratio, which typically range from around 0.1 to 5.0 in soils, are consistent with observations, suggesting that this ratio is a good signature for dust source regions. The simulated variable fractions of chemical elements are sufficiently different; estimates of deposition should include elemental variations, especially for Ca, Al and Fe. The model results have been valuated with observations of elemental aerosol concentrations from desert regions and dust events in non-dust regions, providing sights into uncertainties in the modeling approach. The ratios between modeled and observed elemental fractions range from 0.7 to 1.6, except for Mg and Mn (3.4 and 3.5, respectively). Using the soil database improves the correspondence of the spatial heterogeneity in the modeling of several elements (Ca, Al and Fe) compared to observations. Total and soluble dust element fluxes to different ocean basins and ice sheet regions have been estimated, based on the model results. The annual inputs of soluble Mg, P, Ca, Mn, Fe and K associated with dust using the mineral data set are 0.30 Tg, 16.89 Gg, 1.32 Tg, 22.84 Gg, 0.068 Tg, and 0.15 Tg to global oceans and ice sheets. © Author(s) 2015 en_AU dc.language.iso en en_AU dc.publisher Copernicus Publications on behalf of the European Geosciences Union en_AU dc.subject Dusts en_AU dc.subject Seas en_AU dc.subject Minerals en_AU dc.subject Soils en_AU dc.subject Deserts en_AU dc.subject Climates en_AU dc.title Modeling the global emission, transport and deposition of trace elements associated with mineral dust. en_AU dc.type Journal Article en_AU dc.date.statistics 2016-11-14 - Appears in Collections: Journal Articles\nItems in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.", "pred_label": "__label__POS", "pred_score_pos": 0.7192364931106567}
{"content": "Abstract\nNotch activation has been detected in pancreatic ductal adenocarcinoma (PDAC). However, its role in PDAC metastasis remains unknown. In this study, we identify a Notch-dependent feedback circuit between pancreatic cancer cells and macrophages which contributes to PDAC metastasis. In this circuit, miR-124 regulated Notch signaling in cancer cells by directly targeting the Notch ligand Jagged 1 (JAG1). Auto-amplified Notch signaling promoted the recruitment and activation of macrophages to a tumor-supporting M2-like phenotype via downstream interleukin (IL)-8, CCL2, IL-1α, and uPA paracrine signaling. In turn, activated macrophage-derived IL-6 activated the oncogenic transcription factor STAT3 that directly repressed miR-124 genes via a conserved STAT3-binding site in their promoters, thereby promoting cancer cell EMT and invasion. Disrupting this circuit suppressed liver metastasis in mouse models. Thus, our study suggests that manipulation of this Notch-dependent circuit has a therapeutic potential for the treatment of PDAC metastasis.\nReceived February 5, 2020. Revision received September 11, 2020. Accepted October 28, 2020. Copyright ©2020, American Association for Cancer Research.", "pred_label": "__label__POS", "pred_score_pos": 0.920143187046051}
{"content": "Abstract\nAntimicrobial resistance is a global threat that poses a rising concern. One underlying challenge is the limited number of targets in bacteria affected by the current pool of antibiotics. To potentially help find new targets, we studied a member of the class of antimicrobial natural products named glycocins. We examined the mode of action of sublancin, which contains an unusual and essential glucosylated Cys residue, by monitoring macromolecular synthesis. Sublancin negatively affected DNA replication, transcription, and translation without affecting cell wall biosynthesis. In addition, we confirmed that the presence of the PTS sugar glucose in the medium negatively impacted antimicrobial activity of sublancin. Additionally, sublancin analogues carrying different sugars retained their antimicrobial activity regardless of which sugar was attached to the peptide or the carbon source used. These data suggest a novel mechanism upstream of transcription and translation and are consistent with previous studies suggesting that the glucose uptake system is involved.\nKeywords RiPP antibiotic bacteriocin glycocin glycopeptide ASJC Scopus subject areas Infectious Diseases", "pred_label": "__label__POS", "pred_score_pos": 0.5111262798309326}
{"content": "While Open Educational Resources (OERs) are adopted at rates comparable to traditional publishers in lower division courses, adoption lags behind in niche content areas and pre-professional courses of study. This session highlights efforts to review and increase the availability of OERs in pre-professional and professional training sequences across multiple US universities, with emphases on both curated and student-generated content. Strategies presented during this session will include: (1) The Behavior Analysis Matrix Project, curating and aligning limited available open access and open educational video resources with course competencies. (2) The Task List Glossary Project, a project to crowd-source student generated examples of the professional principles across disciplines, cultural contexts, and learning histories (3) The Open Behavior Artifacts Project, a project designed to support students as content creators in creating mixed format resources to describe and expand examples and reflect diverse student voices. (4) The creation of Special Topics in Applied Behavior Analysis, an openly-licensed textbook created in partnership with graduate students through open enabled pedagogy, limiting the effort involved in creating a brand new resource while maximizing student learning.\nThese strategies, which employ inductive models for OER content creation, emphasize the intentionality of including experiences that represent the learning histories, cultures, and values of a wide variety of developing professionals. Applications of these strategies are discipline-universal, applicable across multiple subject areas.\nLearning Outcomes: Participants will be able to: describe examples of OER curation and student-generated creation, articulate the role of cultural context and anti-bias approaches, and consider ethical replication of similar strategies.", "pred_label": "__label__POS", "pred_score_pos": 0.9597105383872986}
{"content": "“Chaos in the world brings uneasiness, but it also allows the opportunity for creativity and growth.” Tom Barrett\nI came across this quote while I was researching a concept for my next book and I found it quite intriguing. I want to share it with you.\nFor me, chaos is an everyday thing. I live in chaos each every day. My life is chaotic all by itself but the world around me forces it to be even more chaotic. I navigate the chaos with trepidation and uncertainty but lean on my experience and intelligence to figure a way though it and be happy with my solution. I’m not always successful but I continue to work at it.\nI expect that everyone reading this feels the same way.\nOne thing that I have always known is that opportunity is an avenue for growth. What’s new is that I never put it together with chaos.\nThe thought that chaos brings about uncertainty and therefore uneasiness is intriguing enough. Now, I can connect chaos as an opportunity for creativity and growth.\nJust saying.", "pred_label": "__label__POS", "pred_score_pos": 0.5259773135185242}
{"content": "Among the seemingly hundreds of controversies brewing in TCPAWorld is whether a consumer can face a counterclaim for collection of a debt in a TCPA suit brought against a loan servicer or collector for purportedly illegal calls.\nWhile the issue seems straightforward—the debtor owes the money and the defendant should be able to collect (or at least offset) the amount owed on the contract in the TCPA suit—many courts have refused to permit such counterclaims fearing that offensive action by a TCPA defendant might somehow “chill” consumer protection lawsuits.\nWeird.\nWell in a recent case, the Northern District of California applied the “majority rule” and common sense (IMO) by allowing a counterclaim to proceed. In\nNalan v. Access Fin., Case No. 5:20-cv-02785-EJD, 2020 U.S. Dist. LEXIS 198836 (N.D. Cal. October 23, 2020) the Plaintiff (allegedly) stopped paying for his car and received collection calls as a result. The Plaintiff sued the collector, who responded with a counterclaim for the $1,778.00 bucks it was (allegedly) owed.\nThe Plaintiff responded by moving to dismiss the counterclaim asserting a lack of jurisdiction. The Court was unpersuaded and found that the debt and the phone calls arose out of the same nexus of operative facts: “Here, both Plaintiff’s and Access’ claims are related to the underlying automobile loan debt owed by Plaintiff to Access. These claims may be fairly classified as part of the same “case or controversy” and therefore, the Court may exercise supplemental jurisdiction over Access’ counterclaim pursuant to 28 U.S.C. § 1367(a)”\nThis is a great case to keep handy as Defendants often disdain the prospect of facing a lawsuit from a consumer that has failed to pay their obligations and is yet looking for a windfall under the TCPA. Pursuing a counterclaim at least allows the parties to equalize their position between one another and reduce all burdens and obligations to a single judgment. Plus this tactic can be a great class action killer. Feel free to reach out to learn more.", "pred_label": "__label__POS", "pred_score_pos": 0.7732239961624146}
{"content": "The sophistication of modern investment models, the complex nature of today’s global markets and the importance of being data-driven forces financial firms to re-evaluate the way they acquire alternative data.\nToday, the web provides an unprecedented opportunity for financial services firms, offering a wealth of information for predicting industry trends and making more informed investment decisions. The proliferation of e-commerce, smartphones, and social media has magnified the need for capturing financial insights derived by web data. More than ever, web data can offer firms the extra intelligence they need to outperform competitors and stay on top of dynamic markets.", "pred_label": "__label__POS", "pred_score_pos": 0.5761064887046814}
{"content": "Birth injuries occur around the time of delivery, resulting in cerebral palsy, Erb’s palsy and other permanent neurological injuries. The risk of injury increases with multiple gestation births, such as twins and triplets. The American College of Obstetrics and Gynecology (ACOG) has issued recommendations to minimize the risk of injury during management of a twin or triplet delivery.\nThe ACOG recommendations recognize that over 100,000 babies are born from multifetal gestations each year in the U.S. The number has steadily increased since 1980 due to the use of reproductive technology. To capture the risk posed by these births, ACOG states: “Although multifetal births account for only 3% of all live births, they are responsible for a disproportionate share of perinatal morbidity and mortality.” The risk of a poor outcome increases with the number of fetuses.\nThese pregnancies can be complicated by a variety of associated conditions: gestational diabetes, hypertension, preeclampsia, acute fatty liver with coagulopathy, pulmonary embolism, twin-twin transfusion syndrome, and preterm delivery.\nManagement of these pregnancies by an obstetrician requires careful examination and monitoring, and thorough counseling of the mom, typically by a high-risk specialist. Cervical length should be assessed to determine the risk of preterm delivery. A cerclage may be an option to reduce this risk. Other possible interventions include bed rest, uterine activity monitoring, tocolytics and selective fetal termination.\nUnder Ohio law, when birth injuries result from substandard management of multiple gestation births, a claim for medical negligence may exist. Given the complexity of these cases, a qualified medical malpractice attorney will need to carefully review all treatment records and ultrasound imaging with an expert in the field to determine if a meritorious claim exists.", "pred_label": "__label__POS", "pred_score_pos": 0.8814790844917297}
{"content": "New Delhi, October 14: In an aim to provide Internet connectivity to villages in the border and Naxal-affected states, the government has selected Hughes Communications India to connect 5,000 village panchayats in the border and Naxal-affected states as well as in island territories with satellite broadband under the BharatNet project by March 2021.\nThe project is to be implemented under the government's ambitious BharatNet programme by March 2021. Under the project, Hughes India will enable broadband internet connectivity in the gram panchayats by utilising the ISRO's GSAT-19 and GSAT-11 satellites along with the Hughes Jupiter System the de facto standard for satellite broadband implementations.\nMoreover, the project will cover the 5,000-gram panchayats distributed across over 15 states and Union territories. These include the hilly states in North and North-East India, the heavily forested states like Chhattisgarh and Jharkhand, and island territories like Andaman & Nicobar and Lakshadweep Islands. The project will cover areas across Manipur, Meghalaya, Tripura, Mizoram, Arunachal Pradesh, and the Galwan Valley in Eastern Ladakh—places that lack terrestrial connectivity, such as fiber or cable.\nCommenting on the development, Sarvesh Singh, CMD, BBNL, said, “BharatNet is the backbone of Digital India, being created to achieve the objectives of Hon’ Prime Minister’s Digital India Mission. The BharatNet network being created by BBNL is to provide affordable high-speed broadband access to rural citizens and institutions of all the Gram Panchayats of the country We are very happy to be partnering with TCIL and Hughes to leverage satellite broadband to connect gram panchayats that are remote or located in difficult terrain.”\nPartho Banerjee, president & managing director, Hughes India, said, “Hughes is committed to the government’s vision of enabling Digital India, and we are excited about our partnership with TCIL and BBNL as part of BharatNet to bring high-speed connectivity to the remote gram panchayats. The most widely deployed satellite ground platform in the world, the JUPITER™ System will deliver reliable and highly efficient service, introducing more people across rural India to high-speed internet connectivity, enabling significant economic participation and social inclusion.”\nAs a part of the project, Hughes will also be providing solar-powered network operations and user terminals, installing equipment at every site, and manage the services to ensure speeds of up to 10 megabits per second.\nThe government aims to connect all 2.5 lakh village panchayats in the country with high-speed broadband services by August 2021.\nWith the Bharatnet project, the government of India aims to better facilitate e-governance applications like telemedicine access to land records, treasury, police stations, internet access, and many other services in rural India", "pred_label": "__label__POS", "pred_score_pos": 0.7717140913009644}
{"content": "Indole-3-Carbinol\nIndole-3-Carbinol (I3C) found in the brassica family of vegetables. This family includes broccoli, brussels sprouts, cauliflower, and cabbage. I3C improves our bodies' detoxification pathways\nand supports female reproductive health.\nI3C promotes both phase 1 and phase 11 of your liver's detoxification pathways. When our liver detoxifies a substance, two phases are involved. When the first phase finishes, ideally the second phase will complete the process.\nThese phases require different nutrients to function. If we have available nutrients for phase 1, but insufficient nutrients for phase 11, the products of phase 1 may accumulate. These substances are\nmore hazardous after phase 1 than they were to begin with.\nTo avoid this, ample nutrients for phase 11 detoxification are essential. I3C supports\nboth phases of detoxification for ideal liver support.\nAdditionally, I3C increases estrogen metabolism, thus reducing the risks for breast cancer, fibrocystic breast disease, and PMS.\nAn active component of I3C binds to estrogen receptors, thus preventing the opportuntiy for estrogen to exert an effect on our cells.\nWe have many factors in our industrilazed society that create estrogenic effects in our bodies. The foods we eat are often from animals that have been administered exogenous hormones (steroids) to increase their size. These steroids have estrogenic effects in our bodies when we eat meat and dairy products from those animals.\nAdditionally, our own fat cells secrete estogen into our bloodstream. Unfortunately, our obesity rate is reaching very unhealthy levels. One of the results of this excessive condition is the increase in estrogen levels.\nI3C can reduce the negative implications of this situation by passively blocking the estrogen receptors of our cells!\nAnother favorable action of I3C is the promotion of a beneficial ratio of estrogens.\nTo purchase Indole-3-Carbinol from Thorne Research, Please Click the Button Below.\nPlease visit this site's page on Anti Aging Supplements by Clicking Here. This website is dedicated to bringing you valuable information about 100% Whole Food Supplements. Please visit our Homepage by Clicking Here.", "pred_label": "__label__POS", "pred_score_pos": 0.8968561291694641}
{"content": "Teacher beliefs about listening in a foreign language\nIt is advisable to refer to the publisher's version if you intend to cite from this work. See Guidance on citing.\nTo link to this item DOI: 10.1016/j.tate.2014.01.007\nAbstract/Summary\nThis study investigated, through a questionnaire, the stated beliefs and stated practices of 115 foreign language teachers in England regarding listening pedagogy: whether such beliefs and practices reflect the literature on listening, whether beliefs and stated practices converged, and what factors might underpin them. Responses indicated a mismatch between teachers’ stated belief in the importance of teaching learners how to listen more effectively, and the lack of evidence in their stated practice of such teaching, with a focus instead on task completion. Findings are discussed against the accountability agenda of the study’s context, and its implications for teacher development highlighted.\nDownloads\nDownloads per month over past year", "pred_label": "__label__POS", "pred_score_pos": 0.9988044500350952}
{"content": "As May concluded, the cryptocurrency market took a sigh of relief as it was able to close on a positive note. The fifth month of the year saw volatility creep back into the market, contributing to drastic changes in the trading activities of the industry’s users. Similarly, the sudden push in Bitcoin’s price provided a much-needed pump to the altcoin markets too.\nBitcoin, while it was returning 16.16% before May, was returning 26.52% by the end of May. Similarly, the world’s second-largest cryptocurrency, Ethereum [ETH], reported a YTD of 72.94%.\nThis growth of Bitcoin and altcoins was visible in CoinMetrics’ Bletchley Index too. According to CoinMetrics’ latest report, the last week of May saw recovery from most CMBI and Bletchley indexes. However, the top performer was still the CMBI Etheruem Index, having fallen by just 1% last week. It was returning 14.7%, while the CMBI Bitcoin Index reported a growth of 5.7%, after noting a loss of -7.8% the previous week.\nSimilarly, all other indexes like Bletchley 10, 20, and 40 were in the negative over the previous week, but managed to climb up this week to report 9.2%, 9.3%, and 10.6% in growth, respectively.\nAccording to the previous indication, the weekly returns denominated in BTC, Ethereum were still the leader, and this week too, ETH returned 8.6% when denominated in BTC. While the market’s major cryptos were set on a recovery path, its small-cap assets also noted restricted growth. The B10 assets were at a loss of 0.8% last week; however, this week, the index returned 3.3%. Small-cap assets like B40, which were returning almost 7% last week, noted a slowdown and were returning 4.6%.\nDespite such restricted growth, however, all of the Bletchley indexes noted returns between 9% and 11%, indicating uniform strength of the market across all large, mid, and small-cap assets.\nAs Bitcoin’s price surged at the beginning of June itself, the other assets’ caps may also reflect this positive surge in the next week’s index with higher returns.\nYour feedback is important to us!", "pred_label": "__label__POS", "pred_score_pos": 0.9470248818397522}
{"content": "TEI submitted comments on the Modified Nexus Approach for IP (BEPS Action 5) and International VAT/GST Guidelines. Links to the submissions are provided for reference:\nSummary: IP, BEPS Action 5: Accelerated comment process will likely lead to suboptimal results. The singular entity approach to benefit from the IP regime is problematic from a potential restructuring necessity and poses deviations from the arm’s length principle. R&D and patents have been expressly stated as benefitting from the IP regime, whereas other activities are not yet mentioned. Limiting the preferential regime to strictly patents, vs. innovative software, etc., represents a myopic approach. The 2021 expiration date for existing regimes seems too short-sighted for patents that may last 20 years. Summary: International VAT/GST Guidelines Unilateral implementation of such guidelines erodes the neutrality principle, leading to double taxation or double non-taxation. Recommendations should align with the OECD discussions for a reverse charge mechanism in B2B scenarios. Supplier based documentation requirements should be practical and simple. The statement that a VAT/GST registration does not create PE should be moved from a footnote to the body of the document for clarity. The lack of consistency in application of transfer pricing adjustments for VAT/GST will provide increased risk of double taxation. Final rules that are clear and uniformly interpreted should be implemented via simple, consistent, flexible and proportional guidelines. TEI’s comments for these two critical topics convey practical and thoughtful considerations for change prior to final implementation. They should thereby be reviewed to better understand the global context and potential consequences for these actions.", "pred_label": "__label__POS", "pred_score_pos": 0.9763197302818298}
{"content": "Research on public relations measurement has caught the attention of practitioners and academicians for decades. The focus has shifted from evaluating output to measuring outcomes; from setting goals to engaging stakeholders better. Numerous platforms and collaborative efforts have resulted in broad principles and guardrails for public relation professionals to demonstrate value and business impact. The […]", "pred_label": "__label__POS", "pred_score_pos": 0.9743102192878723}
{"content": "As European governments strive toward energy-efficiency targets of 2030 and the broader goal to establish a decarbonized building stock by 2050, water management within buildings has emerged as a key ... »\nCompanies approaching water as a business are often challenged by a lack of high quality, reliable intelligence. Bluefield bridges this gap with actionable, data-backed analysis supported by a transparent research methodology and ongoing access to our global water experts. As an independent insight firm focused exclusively on water markets, executives rely on our suite of research services to validate their assumptions, address critical questions, and strengthen strategic planning processes.\n192 South Street Suite 550 Boston, MA 02111 USA North America: +1 (617) 910 2540\nCarrer de Sant Joan de la Salle 42 Edifici Technova, 2.12 08022 Barcelona, Spain Europe: +34 93 681 4325", "pred_label": "__label__POS", "pred_score_pos": 0.9018484354019165}
{"content": "LUBBOCK, Texas — On Friday, the House of Representatives voted 402-12 to approve a bill extending funding for a 9/11 victims compensation fund until 2092. Representative Jodey Arrington was among the 12 who voted against the bill.\nThe fund was created in 2001 and provides financial compensation to those who suffered physical injury or illness from both the attacks, and the resulting debris clean-up. According to the Associated press, administrators recently cut benefit payments up to 70% in response to the $7.4 billion fund being rapidly depleted.\nAccording to the Congressional Budget Office, the bill would result in approximately $10.2 billion in additional compensation payments over 10 years, including the more than $4 billion for claims that have already been filed.\nThe following is a statement from the office of Jodey Arrington regarding his vote:\n“The horror of September 11, 2001 continues to this day for those whose lives were forever impacted by this unspeakable act of evil. I agree that first responders and victims should not suffer financial hardships due to ongoing medical and other costs related to the attack. However, we should not abandon our stewardship responsibilities and the past practice of ensuring appropriate oversight and accountability by extending the Victim Compensation Fund for seventy years to 2090. I fully support reauthorizing this fund, which is essential to supporting the 9/11 first responders and victims. However, it would be a disservice to both taxpayers and first responders if victims were not effectively compensated and fraudulent claims not prevented as a result of improper oversight and management of the fund. Since its inception, the Victim Compensation Fund has been repeatedly reauthorized for no more than five-year increments, allowing for regular Congressional oversight to ensure the program is working well and appropriately funded. I urge the Senate to apply these standards and reauthorize this important fund in a manner that honors both the victims of 9/11 and the taxpayers.” (The Associated Press contributed to this article)", "pred_label": "__label__POS", "pred_score_pos": 0.967376708984375}
{"content": "The compressive performance of metallic sandwich panels signifies a key mechanical behaviour under compression loading. This paper describes the compressive performance of metallic corrugated core sandwich panels having different core configurations under quasi-static compression loads. Two different sandwich panel core configurations were studied: the corrugated monolithic core and the corrugated sliced core. The corrugated cores were fabricated using a sheet-metal bending technique with trapezoidal geometry and then bonded to surface plates. Aluminium 1050 1114 sheets were used as the core and surface materials. Sandwich panel samples were prepared and tested experimentally under a quasi-static compression load (compression rate of 2 mm/min). The force-displacement curves of the sandwich panels with different core configurations were obtained from the experimental tests. The compressive performance parameters included the maximum compression load, the average compression load, the energy absorption and the specific energy absorption. It was found that the core configuration played a key role in the compressive performance. Finally, when the compressive performance of these two different core configurations was compared, the corrugated sliced-core configurations exhibited better performance.", "pred_label": "__label__POS", "pred_score_pos": 0.5690059661865234}
{"content": "CBE recently launched an online tool for designing with ceiling fans, making it easier for designers to create highly energy efficient and comfortable spaces. The tool was created based on years of research that have demonstrated that ceiling fans can keep a person cool while using only a fraction of the energy required by air conditioning.\nCategory: #personal comfort\nBuilding standards and conventional practice are all about ’reducing the negative‘ — but what if the goal is to ’enhance the positive‘ instead? Aiming to create environments that are not only comfortable and healthy, but are connected to nature, provide a sense of place, and are a delight to be in. Designing for experience requires us to embrace a broader view of\nexperiential aesthetics, going beyond the primacy of vision to recognize broader sensual qualities that contribute to the beauty and memorability of space.\nThis year marks the 25th anniversary of the publication of a seminal paper from Rocky Mountain Institute, “Greening the Building and the Bottom Line,” making the case that green buildings’ unique features may improve employee productivity. Since then interest in this topic has remained strong, and several studies by CBE and others have contributed to our collective understanding of workplace productivity; in this post we describe our related work with a focus on key variables.\nThis spring CBE’s research team received funding to support two new projects that will create new ways to gather, analyze and monetize data from commercial buildings, yielding energy cost savings and more comfort for building users.\nNow in its twelfth year, the Livable Buildings Award recognizes projects that demonstrate high occupant satisfaction, excellent design, and innovative operation strategies. This year, we are pleased to announce the Rocky Mountain Institute Innovation Center as the top winner, with an honorable mention for the Pomona College Millikan Science Building.\nProject Scientist Fred Bauman recently received the ASHRAE Fellow award, a recognition for those who have distinguished themselves in the HVAC industry. His contributions are based on the extensive research on UFAD that he directed at CBE, leading to deeper knowledge and guidance for these advanced HVAC systems. Recently, he has led a similar efforts to address thermally massive radiant systems.\nThe emerging trend toward smart electric vehicles is creating new opportunities for synergistic innovations that are applicable to both buildings and cars. Model-based control concepts, greatly advanced by the automotive sector, are now being tested in the control of complex commercial buildings. These synergies, what we might call the building-automotive nexus, are also reflected in CBE’s body of research on thermal comfort.\nCBE’s “Changing the Rules” Demonstrates an Occupant-Based Paradigm for HVAC Control for Energy Savings and Improved Thermal Comfort\nCBE’s research team recently completed a project with goals of making buildings occupant-responsive in real time, and addressing outdated rules-of-thumb that lead to poor energy performance and occupant comfort. Findings demonstrated that “personal comfort” chairs led to comfort satisfaction for nearly all test subjects. The project team also developed and tested innovative HVAC control methods offering significant energy saving potential.", "pred_label": "__label__POS", "pred_score_pos": 0.9588603377342224}
{"content": "Babies retain even detailed events during a nap\nThe brain is permanently exposed to new impressions. Even when sleeping, it does not rest and processes recent experiences. In very early childhood, it has been thought that sleep primarily promotes semantic memory. This includes general knowledge such as the meaning of words. However, scientists at the Max Planck Institute for Human Cognitive and Brain Sciences (MPI CBS) Leipzig and the Humboldt University (HU) Berlin, together with researchers from Lübeck and Tübingen, have now shown for the first time in their study published in\nNature Communications that babies also build their episodic memory when they nap. This enables them to remember the details of their individual experiences after napping.\nThe scientists examined this relationship using a three-phase study. During the learning phase, the 14 to 17-month-old children were shown pictures of objects whose names they already knew, containing different cars, balls or dogs. They then heard the appropriate name for each picture. One group of the children spent the following one to two hours sleeping, while a second group stayed awake. In the subsequent test phase, the researchers showed the young participants different pictures again, including those that they had already seen in the learning phase as well as new cars, balls and dogs. Each object was once named correctly and once incorrectly. During all phases of the experiment, the researchers recorded the baby's brain activity using the electroencephalogram (EEG).\nThe analysis of the EEG activity made it clear: The brain of the children who had slept responded differently in the memory test than that of those who stayed awake—but only in certain cases. If the researchers presented the babies with a ball that they had never seen before and called it a car, the brain responses initially did not differ. In both groups, the so-called N400 component appeared, which occurs when the brain processes inappropriate meanings. The children obviously knew that a ball is not a car.\nIt was different, however, when the babies viewed a ball from the learning phase and it was called a car. The group that had stayed awake again showed the N400 component, while the group that had slept did not. In the children who had napped, the researchers observed a brain response that was triggered when a ball from the learning phase was again correctly named as such. However, this response did not occur when a new ball was called a ball. The researchers concluded: After sleep, the babies no longer understood the object-word pairs they had previously experienced as naming a meaning. Rather, they recognized them as individual episodes. Object and word were thus merged into a unified event in the memory.\n\"The results show that sleep not only enables the infant brain to generalize individual experiences, but also to preserve individual experiences in detail and to differentiate them from existing general knowledge,\" explains first author Manuela Friedrich, researcher at the MPI CBS and HU Berlin. She further hypothesizes: \"The fact that a recognized object-word episode is not understood as referring to general knowledge means that its details can be protected from mixing with existing memory.\"\nThe results are also interesting with respect to the so-called infantile amnesia, i.e. the phenomenon of not being able to remember one's own early childhood experiences. It has often been assumed that very young children are not yet capable of forming longer-term episodic knowledge. However, the current findings clearly show that even babies can remember events in detail—and sleep contributes significantly to this.\nExplore further\nMore information:Manuela Friedrich et al, Sleep-dependent memory consolidation in infants protects new episodic memories from existing semantic memories, Nature Communications(2020). DOI: 10.1038/s41467-020-14850-8 Journal information:Nature Communications Citation: Babies retain even detailed events during a nap (2020, April 7) retrieved 1 December 2020 from https://medicalxpress.com/news/2020-04-babies-retain-events-nap.html", "pred_label": "__label__POS", "pred_score_pos": 0.8341568112373352}
{"content": "This resource was selected by SMI Adviser content partners and approved by the SMI Adviser clinical expert team for inclusion in the knowledge base.\nThe current Multicultural Guidelines: An Ecological Approach to Context, Identity, and Intersectionality, 2017 (i.e., Multicultural Guidelines) are conceptualized from a need to reconsider diversity and multicultural practice within professional psychology at a different period in time, with intersectionality as its primary purview. The 2017 version of the Multicultural Guidelines encourages psychologists to consider how knowledge and understanding of identity develops from and is disseminated within professional psychological practice. Endemic to this understanding is an approach that incorporates developmental and contextual antecedents of identity and how they can be acknowledged, addressed, and embraced to engender more effective models of professional engagement. The Multicultural Guidelines incorporate broad reference group identities (e.g., Black/African American/Black American, White/White American, and Asian/Asian American/Pacific Islander) to acknowledge within group differences and the role of self-definition in identity.", "pred_label": "__label__POS", "pred_score_pos": 0.8729907870292664}
{"content": "Discussion—Relapse and Pain\nOne of the largest hurdles in recovering from a substance use disorder does not concern getting sober, but rather, staying sober over time. Relapse is a constant threat; clients are consistently battling against their triggers to remain sober. Additionally, many recovering users suffer from pain, sometimes due to the initial conditions that led them to use, or from conditions developed through their chronic substance use.\nKeeping this in mind, respond to the following questions:\n1.Evaluate the most common relapse triggers. 2.Analyze at least two relapse prevention strategies. 3.Explain how pain causes complications in preventing relapse in sober clients. 4.Hypothesize the risks and benefits in sober clients using pain medication as prescribed to help manage their pain.\nUsing information from the textbook, lecture materials, and other scholarly resources, write your initial response in approximately 300–400 words. Please be detailed oriented.", "pred_label": "__label__POS", "pred_score_pos": 0.9983707070350647}
{"content": "While plant available soil water graphs can help create a narrative for the progress of a crop and aid key in-season decision-making, other key factors also need to be considered for any given crop to arrive at an accurate picture. These include:\nsoil status and characteristics including stored soil moisture, soil water-holding capacity and any barriers to infiltration stored nitrogen and other nutrient availabilities factors such as non-wetting, water-logging through topography or impermeable layers, leaching or dispersible clays in the soil", "pred_label": "__label__POS", "pred_score_pos": 0.9983969926834106}
{"content": "Since August 2018, ARCHS has issued $6.1 million to support a portfolio of job development, training, placement and support programs being offered by six area workforce-focused organizations serving St. Louis City and St. Louis County.\nARCHS has issued grants to the following organizations:\n- America Works - Missouri - Better Family Life, Inc. - Employment Connection - Mission: St. Louis - Louis Agency on Training and Employment - Urban League of Metropolitan St. Louis\nARCHS secured funding from the Missouri Department of Social Services to support these initiatives. The primary target population will include SNAP recipients, veterans, homeless individuals and families, justice involved individuals, and those struggling to find full-time, sustainable employment because of barriers to work.\n“This is ARCHS’ largest single investment in workforce related programming in our 20 year history,” said Wendell E. Kimbrough, ARCHS’ Chief Executive Officer.” While we talk about a good economy, and low unemployment rates, there are thousands of people trapped within on-going cycles of intergenerational poverty in St. Louis who need viable skills training and connections to employers.”\nThis funding supports a variety of job readiness and placement services, social services and barrier removal services. It also provides resources for reliable and affordable childcare, remedial education services/GED training, basic skills training, and connection to parenting classes/family mediation services.\nIn addition to funding, ARCHS provides strategic consulting and technical assistance to support its grantees. This includes connecting funded organizations with state and regional resources to enhance their efforts, including Missouri’s SkillUP program. ARCHS partners with its grantees to share resources, coordinate efforts, and foster collaboration.\nARCHS currently funds and strategically enhances more than 30 regional initiatives that improve the lives of more than 180,000 individuals facing disparities and disadvantages in St. Louis’ most impoverished communities. ARCHS works to disrupt cycles of intergenerational poverty by advancing lifelong learning.\nIndividuals interested in learning more about these workforce programs, should contact the ARCHS’ funded organizations directly:\n- America Works – Missouri 1010 Market St., Suite 890, St. Louis, MO 63101 314-492-5430 americaworks.com/missouri - Better Family Life, Inc. 5415 Page Blvd., St. Louis, MO 63112 314-367-3440 betterfamilylife.org - Employment Connection 2838 Market St., St. Louis, MO 63103 314-333-5618 employmentstl.org - Mission: St. Louis 3108 N. Grand Blvd., St. Louis, MO 63107 314-534-1188 missionstl.org - St. Louis Agency on Training and Employment 1520 Market St., Suite 3050, St. Louis, MO 63103 314-589-8000 ext. 3634 stlouis-mo.gov/government/departments/slate/ - Urban League of Metropolitan St. Louis 8960 Jennings Station Rd., Jennings, MO 63136 314-388-9840 ulstl.com", "pred_label": "__label__POS", "pred_score_pos": 0.7987731695175171}
{"content": "Abstract\nAims/Introduction: Pancreatic α-cell area and the α- to β-cell area ratio (α/β) might be associated with glucose tolerance. The aim was to clarify how these histological parameters change as glucose tolerance deteriorates. Materials and Methods: We analyzed pancreatic tissues obtained from pancreatectomies of 43 patients. We evaluated the relationships between α-cell area or the α/β and various clinical parameters. Additionally, we analyzed α-cell proliferation and the expression patterns of various pancreatic transcription factors. Results: The α/β in individuals with longstanding (previously diagnosed) type 2 diabetes (0.36 ± 0.12) was higher than that in those with normal glucose tolerance (0.18 ± 0.10; P < 0.01), impaired glucose tolerance (0.17 ± 0.12; P < 0.05) and newly diagnosed diabetes (0.17 ± 0.12; P < 0.05). In all participants, glycated hemoglobin (HbA1c) correlated with relative α-cell area (P = 0.010). Diabetes duration (P = 0.004), HbA1c (P < 0.001) and plasma glucose levels (P = 0.008) were significantly correlated with the α/β in single regression analyses, and diabetes duration was the only independent and significant determinant in stepwise multiple regression analyses (P = 0.006). The α-cell Ki67-positive ratio in patients with HbA1c ≥6.5% was significantly higher than that in patients with HbA1c <6.5% (P = 0.022). We identified β-cells that expressed aristaless-related homeobox and α-cells that did not express aristaless-related homeobox at all glucose tolerance stages. Aristaless-related homeobox and NK homeobox 6.1 expression patterns varied in insulin and glucagon double-positive cells. Conclusions: The pancreatic α/β increases after type 2 diabetes onset and correlates with diabetes duration. This change might occur through α-cell proliferation and phenotypic changes in pancreatic endocrine cells.\nAll Science Journal Classification (ASJC) codes Internal Medicine Endocrinology, Diabetes and Metabolism", "pred_label": "__label__POS", "pred_score_pos": 0.8731633424758911}
{"content": "In a Domestic Violence Lawsuit lodged by wife, a husband had approached the High Court seeking anticipatory bail apprehensive detention. The court noted that a divorce case between the parties is pending when disposing of his pre-arrest bail appeal. The High Court, therefore, allowed the plea, but by placing a condition that Rs. 20,000 should be paid monthly to his wife. While he filed an appeal seeking to change the order, it was also dismissed.\nIn rebuking these orders, the husband approached the Supreme Court arguing that the proceedings for the grant of anticipatory bail are not the right procedure for the grant of maintenance and the High Court is not the proper venue to determine the maintenance question while hearing the application for anticipatory bail. He relied on the judgment in Munish Bhasin & Ors. v. State (Government of NCT of Delhi) & Anr. (2009) to contend that conditions that can be imposed should be:\nto secure the presence of the accused before the investigating officer or before the Court, to prevent him from fleeing the course of justice, to prevent him from tampering with the evidence or to prevent him from inducing or intimidating the witnesses so as to dissuade them from disclosing the facts before the police or Court or restricting the movements of the accused in a particular area or locality or to maintain law and order, etc.\nIt was pointed out that, in the judgment in question, it would be outside the authority of the power imposed on the Court under section 438 of the Code to enforce any other condition on the accused. In that judgment, the Court set aside the order of the High Court compelling a husband to pay his wife and child support while granting him and his parents' anticipatory bail in respect of a complaint lodged by his wife. Although dismissing his SLP, we see no justification to intervene with the impugned order passed by the High Court, the bench consisting of Justices NV Ramana, Surya Kant, and Krishna Murari observed.", "pred_label": "__label__POS", "pred_score_pos": 0.9481273293495178}
{"content": "Breast cancers may evade the growth-inhibitory action of TGFbeta by accumulating defects of unknown nature that selectively eliminate cytostatic gene responses. We found the transcription factor C/EBPbeta to be essential for TGFbeta induction of the cell cycle inhibitor p15INK4b by a FoxO-Smad complex and repression of c-MYC by an E2F4/5-Smad complex in human epithelial cells. These cytostatic responses are selectively missing in metastatic breast cancer cells from half of the patients that we tested. The basis for this loss was traced to an excess of the C/EBPbeta inhibitory isoform LIP. We suggest that C/EBPbeta plays a key role in the coordination of TGFbeta cytostatic gene responses, and its malfunction may trigger evasion of these responses in breast cancer.", "pred_label": "__label__POS", "pred_score_pos": 0.5567898750305176}
{"content": "Vulnerability of microfinance institutions to climate risk in the Satkhira District, Southwest Bangladesh\nThis paper explores how microfinance institutions are affected by and are responding to flooding, by examining a case study of Satkhira District in Southwest Bangladesh.\nThe authors develop a framework for understanding how microfinance institutions can reduce their vulnerability to climate risks and use the framework to empirically assess local-level practices, drawing from interviews with households and local branch managers as well as household survey data.\nWhile microfinance institutions are directly vulnerable to flooding, their main exposure arises from the exposure and sensitivity of client livelihoods and their lack of adaptive capacity. Branch managers are unable to screen clients for climate risk for ethical, practical and financial sustainability reasons. Branch managers also have limited capacity to manage aggregated risk.\nThe authors argue that efforts should instead focus on reducing client vulnerability, tackling the problem at its source. While much potential exists for microfinance institutions to do this, it is not actively and explicitly being achieved. Loan product innovation could facilitate clients’ adaptation to relevant climate hazards. This requires empirical understanding of autonomous household adaptation to incorporate client knowledge of adaptation needs, options, and associated barriers.\nThe results indicate that homestead loans, disaster management loans, and loans for alternative income-generating activities would help reduce client vulnerability. Integrating non-financial services could also contribute to addressing non-financial barriers to adaptation.", "pred_label": "__label__POS", "pred_score_pos": 0.9548173546791077}
{"content": "Global and Domestic Trade- May 2020\nThe outbreak of COVID-19 has upended attempts to curb rising protectionism, with recessionary headwinds and an expected decrease in world trade between 13% and 32% in 2020 projected to complicate attempts at negotiating an end to residual trade war tensions. Fears over the reinvigoration of protectionism as global trade systems become even more insular has further threatened the progress of globalisation. Specifically, the virus has revealed the \"downsides of extensive international integration\" as the entrenchment of China in global supply chains has increased the transmission of financial contagion globally. The vulnerability of a closely integrated economy, as the OECD has identified, will likely reduce global growth to 1.5% in 2020, with industries that rely on the movement of goods and people as well as those with cross-border supply chains likely to incur the largest costs.\nAustralia remains particularly exposed to changes in the global trade system. Notably it is a small, open economy with a narrow export base. Hence, China has remained a crucial component of Australia's trade narrative, contributing to 60% of our $180 bn net export growth in the past decade. With China's growth expected to reach 1.2% in the midst of COVID-19, Australia's trade sectors can be expected to remain relatively resilient against global trade shocks. Nonetheless, political tensions may undermine this ongoing relationship, as recent coal restrictions and customs inspection rules present a new threat to Australia's export dependency. With US-China trade war tensions slated to escalate, this is a worrying precursor for the future of a globally integrated trade system.", "pred_label": "__label__POS", "pred_score_pos": 0.9001316428184509}
{"content": "When you experience an injury caused by negligence, you can seek legal compensation for your damages. This does not necessarily mean you have to go to court, however.\nReview the alternative dispute resolution (ADR) options to consider after a personal injury in Hawaii.\nArbitration\nHawaii has established the court-annexed arbitration program (CARP) to handle personal injury cases with potential damages of less than $150,000. If your case applies, the arbitration process attempts to resolve your case without a trial. Both sides present evidence to a neutral arbitrator, typically an attorney, who makes a nonbinding decision. That means if you do not agree with the arbitration results, you can pursue mediation or litigation.\nMediation\nWith this option, you work together with the responsible party to reach a settlement that covers the costs of your injuries. A professional mediator serves as a neutral third party during the mediation sessions. If you file a personal injury lawsuit, the judge may refer your case to mediation.\nHawaii resolves most personal injury cases worth more than $150,000 in mediation. Like arbitration, mediation is not legally binding.\nSettlement conferences\nIf your case qualifies for a settlement conference, you negotiate with the other party in front of a judge. He or she might use mediation techniques to help you reach an agreement. In Hawaii, you can request a settlement conference or receive a referral from the judge.\nADR methods are typically less costly and time-consuming than suing the responsible party in court. That means you can move forward with litigation if you cannot reach an agreement in mediation, arbitration or settlement conference.", "pred_label": "__label__POS", "pred_score_pos": 0.7916378974914551}
{"content": "Severe wildfires remove vegetation and organic soil layers and expose watersheds to erosion which can transport large quantities of soil and ash to nearby rivers and streams. But once the burned areas have stabilized, do severe wildfires have any longer-lasting effects on watersheds or water quality? This study follows the Hayman Fire, 2002, Colorado, and shows that yes, there are long-term effects.", "pred_label": "__label__POS", "pred_score_pos": 0.8450775146484375}
{"content": "Being single.\nAfter more than a decade in a relationship, I found myself teetering on cougarhood, suddenly single, and shocked by the reality of being alone. For the first time, I tiptoed into the waters of online dating.\nAnd discovered that dating is a path to spiritual enlightenment.\nIt's because of all the uncertainty. The rampant, horrible, delicious uncertainty.\nWhenever we meet someone, some deep part of our psyche perks up and says, \"I don't know why, but this person that I just met is incredibly important and they could be the absolute key to my happiness and well-being for the rest of my life.\" The endorphins kick in, the toes start to tingle and pretty soon we've imagined the relationship, the marriage, the kids and the divorce before the second date.\nBecause our mind is so uncomfortable existing in a state of uncertainty, it will restlessly ruminate and pick over the smallest scraps of information. Like:\nWhy did he text and not call? or Why did he email and not text? or Why did/didn't he pay the bill? Arrrrrghhhh!\nOr perhaps we're on the other end of the spectrum and the self-protective part of the brain kicks in and puts a big Do Not Enter sign over our hearts. Being bruised before, we withdraw, shut down and lie in wait for someone who won't feel quite as 'dangerous.' The uncertainty factor--not knowing if we can trust this new person--prompts us to find ways to undermine the relationship before it has even started.\nRegardless of whichever end of the spectrum we find ourselves in or relate to, we can benefit from:\nFour Practices for Spiritual Dating:\n1. Admit we don't know.\nIn the ground between these two extremes lies an opportunity to rest in the uncertainty of the situation and come back to our deepest selves, where we can observe the exuberant chattering of the mind rather than trying to control the situation. (Yoga is the restraint of the fluctuations of the mind/Yogascittavrtti nirodhah from Patanjali's Yoga Sutras). When our mind starts telling stories, we can catch on, come back to the present moment and find an internal steadiness that can easily withstand the tempestuous winds of external uncertainty.\n2. Feel more.\nDating can bring up some intense feelings. Use these sensations to become more deeply connected to yourself and the present moment--without attaching a story or narrative to them.\n3. Practice courageous honesty.\nAs we become more centered, we can practice owning and articulating our own satya (truth). Whether that's saying, \"I really like you,\" \"This isn't working for me,\" or \"I don't know,\" we can use this unusual landscape as an opportunity to practice being connected, brave and clear.\n4. Trust.\nPracticing honesty allows us to trust that everything is unfolding as it ought. Isvara pranidhana (surrender to God). To have a full understanding for the context that we are participating in, we must ride the waves-knowing that we can't see the next one coming. We can either surf or fight the undertow. So take a deep breath, feel your body and dive in.\nUltimately, the water's just fine.\nFollow HuffPost Canada Blogs on Facebook", "pred_label": "__label__POS", "pred_score_pos": 0.5399842262268066}
{"content": "DHL and Chambers Survey Indicates Growing Confidence\nThis week’s release of the DHL/British Chambers of Commerce Trade Confidence Index report shows encouraging results for UK businesses.\nAcross all measures improvements have been seen. The British export index is at an all-time high, increasing by 2.85% over Q1 2013 and exporter’s confidence in future turnover also remains high, with a notable increase in confidence from manufacturing firms.\nFurther breakdown of the export sales balance reveals that 48% of exporters reported increased export sales in Q2 2013; 10% of respondents stated that they decreased, and 42% stated that sales remained constant. In the services sector the balance of exporters reporting that sales had increased rose by 12 points to +46% in Q2 2013. In the manufacturing sector the export sales balance continued to fluctuate widely and now stands at +28%. This is double the balance figure recorded in Q1 2013, but it is two points lower than the Q4 2012 balance", "pred_label": "__label__POS", "pred_score_pos": 0.986855149269104}
{"content": "Objectives: To compare immediate cessation of nasal continuous positive airway pressure (NCPAP) vs. a stepwise decrease in pressure on the duration of NCPAP therapy in infants born prematurely. Study design: A single center study in infants 230-326 weeks gestational age (GA). NCPAP was stopped either at 5cm H2O (Control) or 3cm H2O after a stepwise pressure wean (Wean) using defined stability and failure criteria. Primary outcome is total NCPAP days. Results: We enrolled 226 infants; 116 were randomly assigned to Control and 110 to the Wean group. There was no difference in the total NCPAP days between groups (median (25th,75th centiles) 16 (5,36) vs 14 (7,33) respectively). There were no differences between groups in secondary outcomes, including duration of hospital stay, critical care days and oxygen supplementation. A higher proportion of Control infants failed the initial attempt to discontinue NCPAP (43% versus 27%, respectively; P < .01) and required ≥2 attempts (20% versus 5%, respectively; P<0.01). Additionally, infants 23-27weeks GA in the Wean group were 2.4-times more likely to successfully stop NCPAP at the first attempt (P=0.02) versus Controls. Conclusion: Discontinuation of NCPAP after a gradual pressure wean to 3cm H2O did not decrease the duration of NCPAP therapy compared with stopping from 5 cm H2O in infants ≤32 weeks GA. However, weaning decreased failed initial attempts to stop NCPAP, particularly among infants <28 week GA.", "pred_label": "__label__POS", "pred_score_pos": 0.7335838079452515}
{"content": "Since nearly all biological phenomena are mediated by genes, gene targeting is impacting the analysis of nearly all aspects of mammalian biology, including studies in evolution, development, neurobiology, immunology and human disease. This technology has many applications for clinical medicine. Scientists can simulate any human genetic disease in laboratory models, study its progression, and test potential therapies against it. In the future, since the investigator can choose which gene to modify and precisely how to modify it, therapies based on gene targeting will be used to correct the endogenous defective gene in the appropriate human tissue. These therapies will be directed at the cause rather than at the symptoms of the disease.\nAn immediate application of gene targeting to human medicine is to generate animal models for human disease such as diabetes, atherosclerosis, hypertension and cancer. These models provide a unique opportunity to undertake in-depth analysis of the pathology of human diseases, and they offer a platform for developing new therapeutic protocols.\nLab Website (link)", "pred_label": "__label__POS", "pred_score_pos": 0.5554155111312866}
{"content": "Kordel’s Organic Calcium is a unique marine multi mineral complex, providing calcium, magnesium and 72 other trace minerals that supports healthy bone density and strength.\nThe body uses calcium, magnesium, phosphorus and many other minerals to build bone and joint tissue. They are also needed for many essential body functions, including muscles and heart movement and nerve transmission. Kordel’s Organic Calcium tablet contains Aquamin™, derived from a unique seaweed with 74 naturally present trace minerals in a honeycomb porous structure, making it easier for the body to absorb and use it nutrients.\nDosage: Adults take one tablet one to two times a day, before food, or as directed by a healthcare professional. Breastfeeding mothers: Take two to three tablets a day, or as directed by a healthcare professional.\nFormulation:\nAquamin™ calcified red seaweed (Lithothamnion calcareum) 1000 mg Elemental Calcium 281 mg Elemental Magnesium (with 72 other naturally-present marine minerals in a trace quantities) 20.6 mg", "pred_label": "__label__POS", "pred_score_pos": 0.9761856198310852}
{"content": "Publicly available satellite imagery can be an ubiquitous, cheap, and powerful tool for vehicle localisation when a prior sensor map is unavailable. However, satellite images are not directly comparable to data from ground range sensors because of their starkly different modalities... We present a learned metric localisation method that not only handles the modality difference, but is cheap to train, learning in a self-supervised fashion without metrically accurate ground truth. By evaluating across multiple real-world datasets, we demonstrate the robustness and versatility of our method for various sensor configurations. We pay particular attention to the use of millimetre wave radar, which, owing to its complex interaction with the scene and its immunity to weather and lighting, makes for a compelling and valuable use case. (read more)PDF", "pred_label": "__label__POS", "pred_score_pos": 0.959162712097168}
{"content": "Each user of interactive systems experiences prolonged engagement with applications, products and systems. Because of limitations of contemporary long-term user research methods and imperfection in human memory, approaches for longitudinal user experience are still under-explored. In this paper, we review a recent methodological shift in user research aimed at applying visual approaches to the capturing of prolonged interactive use. We analyze and discuss selected examples of existing visual approaches that support the examination of longitudinal use and represent and visualize changes in interactions. We discuss potential merits of visual approaches for user experience longitudinal research. We also discuss the drawbacks of these approaches. Overall, we argue that visual approaches have the potential to support certain aspects of user experience research, especially in relation to issues concerning temporality.", "pred_label": "__label__POS", "pred_score_pos": 0.5477938652038574}
{"content": "Sen. Mark Warner (D-Va.) is urging the Department of Labor to issue guidance for states scrambling to give gig and self-employed workers access to unemployment benefits.\n“The CARES Act directs states to stand up a new program, the Pandemic Unemployment Assistance (PUA) Program, to disburse benefits to workers who would normally not be eligible for unemployment assistance, such as gig workers or freelancers,” Warner wrote to Labor Secretary Eugene Scalia in a letter Friday.\n“Unfortunately, we are already hearing reports from unemployment officials from around the country that it will likely take weeks to stand up a new program and disburse benefits to these newly eligible workers. In the middle of the COVID-19 pandemic, with unemployment claims overwhelming state systems, there is no time to waste.”\nThe $2 trillion coronavirus relief package, the Coronavirus Aid, Relief, and Economic Security (CARES) Act, signed by President Trump last week gives those workers access to unemployment benefits. But states have struggled to make those benefits available quickly, given a historic surge in workers seeking unemployment benefits as the coronavirus pandemic batters the economy.\nThe Department of Labor issued initial guidance on the CARES Act late Thursday, but Warner said it must streamline the PUA program, require states to allow applicants to submit electronic documents and find innovative ways to speed up relief.\n“While I appreciate the initial round of guidance that was released yesterday, the Department of Labor should have already issued more comprehensive guidance to states this week,” he wrote.\nThe spread of the coronavirus has highlighted the precarious situation of American gig and self-employed workers who are not guaranteed access to traditional unemployment benefits or health coverage.\nSeveral workers in contractor heavy industries have engaged in strikes to demand better protections from their employers.", "pred_label": "__label__POS", "pred_score_pos": 0.516241192817688}
{"content": "Abstract\nRosai–Dorfman disease (RDD) is an uncommon histiocytic proliferative disorder that can present in nodal, extranodal, or, extremely rarely, in central nervous system (CNS)-restricted form. RDD is characterized histologically as a non-Langerhans cell histiocytosis composed of atypical CD68\n+/S-100 +/CD1a – macrophages demonstrating prominent emperipolesis and effacement of the surrounding tissue. Previously thought to represent a reactive process, recent studies have raised the possibility that RDD and other histiocytic lesions, including Erdheim–Chester and Langerhans cell histiocytosis, are clonal processes linked to somatic mutations in the mitogen-activated protein (MAP) kinase pathway. Herein, we present a fatal case of RDD isolated to the CNS and used a next-generation targeted gene panel and Sanger sequencing to uncover a pathogenic deletion in the β3-αC loop of the kinase domain in exon 12 of BRAF. This mutation, previously described in melanoma and Langerhans cell histiocytosis, represents the first BRAF mutation of this kind identified in RDD. These findings support the idea that RDD is a neoplastic condition and raise the possibility that inhibitors of the MAP kinase pathway may be effective in RDD. Ann Neurol 2018;83:147–152. ASJC Scopus subject areas Neurology Clinical Neurology", "pred_label": "__label__POS", "pred_score_pos": 0.8009310960769653}
{"content": "SESSION THEME | Voices - te ao Māori BICULTURAL PLACE-BASED TOOLS Wednesday 1 April,\nAmong spatial planning tools, place-based tools are developed to support indigenous communities in decolonising urban planning. In Aotearoa New Zealand, place-based tools can support the documentation and transference of local mātauranga Māori, ensuring that such learnings can be weaved into urban planning decisions. This paper presents two place-based tools currently being co-created with two Māori communities, Ngāi Tūāhuriri (Waimakariri) and Ngāti Whakaue (Rotorua). In Tuahiwi, Waimakariri, the place-based tool aims to assist Ngāi Tūāhuriri in documenting traditional and lived, place-based, narratives to guide the socio-economic regeneration of the village. In Ōhinemutu, Rotorua, the place-based tool also aims to support Ngāti Whakaue in preserving and enhancing local narratives, specifically related to ngāwha (hot springs) as a starting point to document socio-environmental narratives which should direct the urban regeneration strategy of the village. Narratives can include mythologies, collective histories passed throughout generations, and lived experiences of more recent times. These narratives can include written stories, songs, sayings, poems or art forms, with mātauranga Maori encoded within. The presentation of these narratives includes geographical information and a time scale, and can be accessed through multiple themes or knowledge guardians. Primarily, these geospatial tools aim to support Māori communities in urban regeneration processes, through spatial narratives connecting tangata and whenua, while offering a better understanding of such dynamics to planning authorities. Although the transferability and adaptability of the place-based tools to other places in Aotearoa requires further investigation, the co-creation methodology adopted and some of the\nPresenters: Maria Rita De Dionisio & Dean Walker Co-Authors: Angus Macfarlane, Simon Kingham, Hirini Matunga & Maarit Kahila-Tani MARIA RITA DE DIONISIO Lecturer of Human Geography, University of Canterbury\nRita is currently a lecturer at Te Kura Aronukurangi University of Canterbury. Rita's research is focused on collaborative planning, urban regeneration, and community resilience. Rita's experience has been developed through projects focused on the social and environmental sustainability of neighbourhoods and cities, through engaged research.\nDEAN WALKER Research Associate, University of Canterbury\nDean is a Research Associate at the Geospatial Research Institute, University of Canterbury. Prior to this he worked as a resource management adviser in Nelson for over 20 years. Much of his work has been with iwi groups including the development of culturally-based environmental monitoring tools. In his current role he is working with Ngāti Whakaue in Rotorua and Ngāi Tūāhuriri in Waimakariri co-creating 'flax-roots' tools to enable community groups to be more engaged in the planning process.", "pred_label": "__label__POS", "pred_score_pos": 0.9403280019760132}
{"content": "\"In the middle of difficulty lies opportunity.\"\nThe socioeconomic impact of Covid-19 has prompted an urgency to pursue a reform of various aspects of the economy. Many of these have already been identified through various studies but have, thus far, witnessed only moderate change, often being neglected due to the relatively fast growth rates in real GDP since at least 2015.\nHowever, with the outlook of recession brought about by the pandemic, the need to focus on improving the economy’s productivity and competitiveness is once more elevated. The key to success is linked to effective cooperation between the government and the private sector.\nThis paper outlines our thinking around various measures that could be pursued to achieve this combined objective, recognising that going back to the old normal is not a viable option, and making the best of the new-normal is indeed the only option.\nIt also includes additional considerations, including our collective responsibility to adhere to health and safety measures, as we head towards a gradual return to normality so as to avoid the need to re-introduce stricter restrictions.\nVassilios Vrachimis\nPartner, Advisory, PwC Cyprus\nTel: +357-22555128\nPolyvios Dionysiou\nSenior Manager, Advisory - Health Industry, PwC Cyprus\nTel: +357-22555543\nChristina Orphanidou\nManager, Advisory - Data, Analytics & AI, PwC Cyprus\nTel: +357-22555420", "pred_label": "__label__POS", "pred_score_pos": 0.9974059462547302}
{"content": "Non-Surgical Saddle Nose Deformity Repair (Facial Filler Injections – Minor Deformity)\nSome saddle nose deformities are slight, with only a minor depression of the nasal bridge. While it may be minor in comparison to more severe cases, it is usually not minor to the patient. A dip in the nasal bridge can affect the overall balance of the face. The nose can seem flat or concaved, detracting from other positive features. Dr. Maurice Khosh is a dual board certified facial plastic surgeon who offers both surgical and non-surgical treatments to repair saddle nose deformities.\nThe first and key symptom of a saddle nose deformity is the collapse of the nasal bridge. While some people lose extensive amounts of cartilage and have a severe nasal collapse, others may only have a minor deformity. A perforated septum or weakened septum may be enough to allow the bridge to sink but not collapse completely. With minor saddle nose deformities, there are more options available for repair. Rhinoplasty is a permanent solution to raise the height of the bridge, but there are also non-surgical treatments available.\nDermal Fillers for Saddle Nose Correction\nFor those who want to correct a minor saddle nose deformity, Dr. Khosh offers non-surgical treatment. Certain facial fillers can replace lost volume and height on the nasal bridge, improving the appearance of the nose. Dermal filler injections are non-invasive and can be completed in an office visit. The results are immediate and can last for several months or longer. This is a temporary option to diminish the appearance of a saddle nose deformity. To maintain the results, additional injections must be used as needed.\nNon-surgical saddle nose repairs are a cost-effective option, and they can be a temporary solution until surgery is completed. If you have a minor saddle nose deformity and want to explore the options available for repair, contact the office of Dr. Khosh in NYC to schedule an appointment.", "pred_label": "__label__POS", "pred_score_pos": 0.875975489616394}
{"content": "Surgical Saddle Nose Deformity Repair (Cartilage Grafting – Major Deformity)\nSevere saddle nose deformities are a result of anatomic changes to the nose structure. Nasal bone and cartilage have been damaged or lost, resulting in the collapse of the bridge and often a shortening of the nose and upturning of the nasal tip. To correct major saddle nose deformities, surgical intervention is needed. Dr. Maurice Khosh is a highly experienced facial plastic surgeon who specializes in this complex type of nose reconstruction.\nRhinoplasty Versus Saddle Nose Surgery\nRepairing a severe saddle nose deformity requires plastic surgery or rhinoplasty. However, saddle nose repairs are not a typical “nose job,” or rhinoplasty. Most rhinoplasty procedures are used to reduce size, remove a dorsal hump or create narrower nostrils. The nose only needs to be shaved or shaped into a different silhouette.\nWith a saddle nose deformity, the nose must be rebuilt. In many cases, the septum and upper/lower lateral cartilage that support the nose have been diminished. This is a much more complex process, requiring cartilage grafting to restore the support of the nose. This must be done before the shape can be addressed. Cartilage can be harvested from a rib or ear, then carefully shaped and grafted to restore the nose structure. If there is a breathing obstruction, stents may be needed. After the structure is restored, the aesthetics of the nose must be considered to create a balanced nose that looks natural.\nDr. Khosh enjoys the challenge of repairing saddle nose deformities and has achieved excellent results for his patients. While it is more difficult than conventional rhinoplasty, the difference it can make in the life of someone living with a saddle nose deformity is worth the extra effort.\nIf you have a severe saddle nose deformity, contact the office of Dr. Khosh in Manhattan to schedule a consultation. You will not find a better plastic surgeon in NYC for performing this complex procedure.", "pred_label": "__label__POS", "pred_score_pos": 0.9538635611534119}
{"content": "A motorcyclist is in critical condition from injuries sustained in a serious multiple-vehicle accident in Fairview Heights, Illinois. The multiple-vehicle accident occurred at approximately 3:00 p.m. on Lincoln Trail and Pasadena Drive. Exact details of the accident are unknown but several witnesses called 911 for emergency assistance. The motorcyclist was airlifted to a hospital where his condition remains unknown. The accident shut down Lincoln Trail for over an hour while police investigated the auto accident. The multiple-vehicle accident remains under investigation and it is unclear if any charges will be filed.\nMany Missouri motorists are passionate about riding their motorcycle. Riding a motorcycle offers the driver an experience, unlike a car or truck. However, many motorcycle accidents can often become serious due to the motorcyclist’s lack of protection. When up against a car or a truck on a roadway, a motorcyclist can quickly become the injured victim in an auto accident. Most motorcyclists have learned to drive defensively, but distracted drivers remain on Missouri roads. If your loved one has been hurt in a motorcycle accident, you may be entitled to monetary compensation for damages. If you believe your accident was caused by the misconduct or distraction of another driver, seek legal help immediately. Experts in Missouri motorcycle accidents at Meyerkord & Kurth, LLC, have represented hundreds of motorcycle accident victims and have recovered millions in paid claims. Don’t let too much time pass after your motorcycle accident; contact a Missouri motorcycle accident lawyer at Meyerkord & Kurth, LLC, today.", "pred_label": "__label__POS", "pred_score_pos": 0.6564038991928101}
{"content": "By Andrew Pisani\nAt an industry meeting on February 7, 2017, the Department of Buildings (DOB) addressed Temporary Place of Assembly Certificates of Operation (TPAs). These permits are designed to protect attendees of events in locales without a Place of Assembly Certificate of Operation (PA) in place.\nTPAs are issued to non-typical public assembly spaces for one-time events where the expected attendance will be 75 persons or greater. Examples include the following:\nA book store for a book signing A retail store for a grand opening A commercial space for a Fashion Week runway show An outdoor concert (Note: Exterior locations trigger TPAs at 200 attendees.)\nLike regular places of assembly, these temporary gatherings also need to comply with zoning regulations and fire safety compliance.\nUnfortunately, the DOB has recently encountered life-safety issues at TPA sites when inspecting venues on the day of the event. As a result, the agency may now conduct inspections before issuing the TPA to ensure compliance.\nIn addition, the DOB reiterated that New Buildings will not receive TPA approval without a Temporary Certificate of Occupancy (TCO) in place.\nTPA Filing Guidelines\nBefore issuing a TPA, the DOB requires an application letter from a registered design professional that describes the proposed space and activity for the event, including signed and stamped drawings.\nTiming.TPA applications must be filed at least 10 business days before the event. The DOB does not guarantee the approval of any requested TPA. (Remember, issuance of a TPA is a “privilege” granted by the DOB, with requests taken on a case-by-case basis.) Fees.The minimum application fee is $250. If the application is not submitted at least 10 business days before the event, the fee increases $100 for each day after the 10-day cutoff. For example, submitting an application only six days in advance would incur an additional $400 charge. ($100 x 4 days late + $250 = $650)\nAlthough the TPA process has typically been straightforward, requirements have become more stringent in recent years. The following issues can thwart a TPA application:\nA New Building TCO cannot state “core and shell only”; it must say “retail.” Properties cannot have a stop work order, either partial or full. A building cannot have an open ECB violation for “work without a permit” on the affected floor. Buildings with elevator violations may not be issued TPAs above street level. (The commissioner may request a letter from the elevator company confirming that the violation has been cured and the elevator functions safely, that they are waiting for official violation dismissal.)", "pred_label": "__label__POS", "pred_score_pos": 0.6838061809539795}
{"content": "In educational and industrial psychology, utilitytheory has been used for determining optimal decision-theoreticprocedures such as optimal test cutting scoresfor Pass/Fail and Accept/Reject decisions. Three methodsare described for empirically assessing utilityfunctions: (1) a method for scaling utility mixtures,consisting of a true achievement or criterion levelcombined with the probability of passing the test orbeing accepted, which is applicable for determiningoptimal decision procedures; (2) a method for scalingthe utility as a function of the true achievement or criterionlevel; and (3) a graphical procedure for choosinga utility function. These methods are useful for investigatingthe utility structure. The three methods areinvestigated using 30 students in a hypothetical educationalPass/Fail situation and appear to yield reliableinformation. Moreover, an overview of the students’utility structures is reported.\nVrijhof, Bastiaan J, Mellenbergh, Gideon J & Van den Brink, Wulfert P. (1983). Assessing and studying utility functions in psychometric decision theory. Applied Psychological Measurement, 7, 341-357. doi:10.1177/014662168300700310\nSuggested Citation\nVrijhof, Bastiaan J.; Mellenbergh, Gideon J.; Van den Brink, Wulfert P..(1983).Assessing and studying utility functions in psychometric decision theory.Retrieved from the University of Minnesota Digital Conservancy,http://hdl.handle.net/11299/101767.\nContent distributed via the University of Minnesota's Digital Conservancy may be subject to additional license and use restrictions applied by the depositor.", "pred_label": "__label__POS", "pred_score_pos": 0.688278079032898}
{"content": "China’s housing rental transaction service platform operator Ke Holdings has filed a preliminary prospectus for a U.S. initial public offering on July 24, aiming to be listed on the New York Stock Exchange (NYSE) under the symbol “BEKE”.\nRenting an apartment in China is not that hard. There are a variety of online rental platforms providing customized services to both Chinese and foreign tenants.\nAs the COVID-19 outbreak left many Chinese families struggling to pay their rents and mortgages, several cities introduced “relaxed” home purchase policies to alleviate people’s burden and reanimate the stagnating real estate market.\nAccording to Bloomberg, the Chinese real estate platform Beike Zhaofang (Beike), has been working with a consultant on a potential IPO and may complete its listing as soon as 2020.\nFor average working professionals in Beijing, Shanghai, or Hong Kong, buying a place for themselves would be a mission impossible.\nFor the vast number of migrants in China, house rental has been a hard issue. House purchase is faced with many policy constraints and the price is too high to afford the house. So for them, renting seems to be the only option available. For the vast number of migrants in China, house rental has…", "pred_label": "__label__POS", "pred_score_pos": 0.5007568597793579}
{"content": "Forecasting and reliability\nForecasting plays an important role in maintaining the reliability of the National Electricity Market (NEM). By providing a clear understanding of the expected challenges to, impacts on, and usage of the system, it allows government and industry to make effective investments and decisions. This section of the site therefore captures key forecasting reports and publications relating to system reliability.\nIn this section\nThis section of the site includes the NEM Electricity Statement of Opportunities (ESOO), which provides a 10-year forecast for electricity supply, demand and reliability in the NEM. It also includes the Energy Adequacy Assessment Projection (EAAP), which provides information on the impact of potential energy constraints.", "pred_label": "__label__POS", "pred_score_pos": 0.8767763376235962}
{"content": "The EU as a Conflict Manager? The Case of Georgia and Its Implications\nCo-authored with Richard G. Whitman and subsequently published in\nInternational Affairs (vol. 86, no. 1, 2010), this paper offers an analysis of the EU’s engagement in Georgia as a standpoint from which to assess the EU’s role as a conflict manager. The paper begins with a brief narrative account of the development of EU-Georgia relations in the context of the country’s two unresolved conflicts over Abkhazia and South Ossetia. It then proceeds to the analysis of two sets of factors — those within, and those external to, the EU — that are crucial for understanding the nature and impact of EU efforts to manage the two Georgian conflicts. On the basis of this case-study analysis, a wider analysis is offered of the EU’s potential for assuming a wider role as an international security actor. This is undertaken by considering both the limitations of the EU’s existing capabilities for conflict resolution and the new developments contained within the Lisbon Treaty. The final part of the paper asserts that the EU has suffered from two key weaknesses that have prevented it from living up to its aspirations of becoming a globally significant and effective conflict manager. The first is structural, namely the lack of, to date, a permanent External Action Service; the second is conceptual, namely the lack of a coherent and comprehensive conflict management strategy. The article concludes with five substantive principles that should guide the EU’s approach to conflict management. Published\nJanuary 2010", "pred_label": "__label__POS", "pred_score_pos": 0.9954267740249634}
{"content": "HMRC have published a consultation into potential measures to curb the evasion of Tobacco Duty in the UK. Landlords of commercial premises should be aware of two of the provisions:\n1. HMRC will ask landowner associates to put a clause into their standard leases banning illicit tobacco and excise trading on their premises.\n2. HMRC will also create a duty of care on landlords to prevent illicit trading on their premises. This would only apply if the landlord had already been notified that the tenant had evaded tobacco duty. Landlords would then be required to take steps including:\nWriting a provision into the lease that it will be terminated if the tenant engages in illicit excise trading and evict tenants that do not comply with this.\nProviding HMRC with a copy of the tenancy agreement.\nUndertaking regular checks on the premises and requesting information about their business.\nTaking steps to ensure they are aware of illicit activity, contacting HMRC or Trading Standards if they have concerns.\nConclusion\nInclusion of a standard term prohibiting illicit excise training is not a particularly controversial position to take. In fact, as the consultation notes, this will often be subsumed by common existing clauses preventing illegal behaviour on the premises.\nThe duty of care is much more onerous however. This could potentially force landlords to carry out expensive and time consuming checks to avoid liability, especially where the tenant is in an existing lease that does not include the provision banning illicit tobacco trading and therefore cannot easily be evicted.", "pred_label": "__label__POS", "pred_score_pos": 0.5945729613304138}
{"content": "There is an old adage that “adversity builds character.” However, before adversity builds character, it reveals character, and the numerous catastrophes that have occurred over the last several years combined with the ongoing pandemic have clearly revealed the character of the insurance industry.\nAnd there is a lot to be proud of in how well the industry has responded time and again to numerous crises. The (re)insurance sector is well-versed at navigating market-changing events, and while the impact of previous shock events such as Hurricane Andrew, the terrorist attacks of September 11, 2001 and Hurricane Katrina may have resulted in a loss of capital and reduced capacity in the short-term, the market responded to each occasion by innovating, working with governments and attracting more capital in the long term. Since 2017, catastrophe claims in the United States alone have totaled USD 214 billion. Despite that, the capital supporting the reinsurance sector has risen to a near all-time high of USD 471 billion, according to John Trace, CEO, North America, Guy Carpenter, and Jay Dhru, Global Head of Business Intelligence, Guy Carpenter.\nSpotting the Black Swans on the Horizon\nWhile it is important to think about black swan events, putting too much time and effort into planning for a specific event at a specific time may be a fool’s errand. Despite being a known risk, a pandemic was not on the risk radar for many people prior to COVID-19. Even in those instances where a black swan event is identified, preparing for such a crisis during good times will always look more expensive. Therefore, instead of focusing on a specific event, (re)insurers are best served by maintaining capital resilience, access to liquidity, strong risk management, nimble operations and innovative thinking.", "pred_label": "__label__POS", "pred_score_pos": 0.7469393014907837}
{"content": "On June 16, 2020, the Federal Government announced that the Canadian Emergency Response Benefit (“ CERB”) will be extended through to the end of August 2020.\nCERB provides taxable payments of $2,000 for a four-week period ($500 per week) to eligible Canadians, including those who have lost their job, are unable to work or whose hours were reduced due to the COVID-19 pandemic. The CERB benefit was originally scheduled to cease effective July 4, 2020.\nBeginning July 5, 2020, CERB recipients will be required to sign an attestation acknowledging that the government is encouraging them to actively look for work. Although it is expected that recipients will not turn down reasonable work opportunities, recipients are not, and will not be under any obligation to accept employment opportunities. This may make it difficult for employers to have recalled employees return to work when they may be earning more money by remaining on the CERB program. A refusal to return to work when recalled usually results in an employer being able to take the position that the employee has resigned their employment.\nThe COVID-19 pandemic is creating novel challenges for employers. Our labour and employment team is closely monitoring this evolving situation and can assist employers to manage COVID-19 in their workplace.", "pred_label": "__label__POS", "pred_score_pos": 0.5618927478790283}
{"content": "Benoît Cœuré, a member of the executive board of the ECB, recently\nspoke about priorities and challenges facing European capital markets.\nHe asserted that finance market fragmentation has become an increasingly significant issue on a global level, being driven by a range of factors from technological developments to political protectionism. While he noted that certain manifestations of market fragmentation could bring benefits such as mitigating cross-contagion risks, in the eurozone low risk sharing across boarders carries the prospect of country-specific shocks having unduly material echoes across the eurozone.\nM. Cœuré said that Brexit must lead to increase capital market across the EU, to accomodate the expected relocation of over €1 trillion in assets from the UK. He proposed that the approach to achieving this should focus on three areas in particular:\nharmonisation of insolvency frameworks, in order to safeguard trust and legal certainty for issuers and investors; supervisory convergence and the oversight and supervision of central counterparties; and diversification of external funding for the real economy, moving away from the current reliance on bank lending, and in particular addressing the post-Brexit gap created by the additional restrictions that will be placed on UK private equity funds wanting to market in the EU.", "pred_label": "__label__POS", "pred_score_pos": 0.6782811880111694}
{"content": "More and more State Medicaid agencies are turning to pay-for-performance incentives to improve health outcomes and lower costs. However, engaging the Medicaid population to attain these quality-based incentive goals is extremely challenging and requires personal motivation to get members to take action.\nEnter Eliza - our Health Engagement Management solution is the only single-vendor solution capable of\ndelivering a truly personalized two-way conversation that helps motivate members to engage in their healthcare journey.\nThis complimentary eBook examines the issues that complicate Medicaid member engagement and proven strategies to improve health outcomes and lower costs. It includes a comprehensive case study illustrating how Eliza’s Health Engagement Management solution delivers improved quality measures while managing costs.\nKey takeaways:\nView the new eBook now.", "pred_label": "__label__POS", "pred_score_pos": 0.9949584603309631}
{"content": "Big problems are rarely solved with commensurately big solutions. Instead, they are most often solved by a sequence of small solutions, sometimes over weeks, sometimes over decades.\nYou can’t appreciate the solution until you appreciate the problem. I think this brings up the question…how often are you using the products you build and sell?", "pred_label": "__label__POS", "pred_score_pos": 0.9906285405158997}
{"content": "Abstract\nA series of molecular dynamics (MD) simulations have been conducted to investigate the heat transport in terms of the phonon dynamics in nanoscale silicon (Si). This work is motivated by a concern over the stagnation of heat at the drain region of nanoscopic transistors, owing to this, a large amount of optical phonons with a low group velocity are emitted from hot electrons, which are ballistically transferred through channel region. The point of this work is the explicit inclusion of the SiO\n2 film in the MD simulation of the Si lattice. The calculation results show that longitudinal optical (LO) phonons decay faster as Si lattice thickness decreases and turn into acoustic phonons. In contrast, thermal diffusion rate decreases with Si lattice thickness. Both the decay rate of LO phonons and thermal diffusion rate are not governed by oxide thickness. These results imply that the phonon scattering at the SiO 2/Si interface is enhanced by thinning the Si layer. In nanoscopic devices, a thin Si layer is effective in diminishing the optical phonons with a low group velocity, but it hinders the subsequent heat transport. ASJC Scopus subject areas Engineering(all) Physics and Astronomy(all)", "pred_label": "__label__POS", "pred_score_pos": 0.5082651972770691}
{"content": "Public pronouncements are regularly made by political leaders to ban plastic use. These have not, however, received a firm and determinative response. For instance, it was announced by the Prime Minister that India will be made plastic pollution free, but a blanket ban on single-use plastic as part of a broader campaign to “rid” India of it by 2022 was held off. It is a measure that was perceived to cause further disruption in the economy that is facing a slowdown, as it could lead to a closure of about 10,000 industrial units, besides inviting the dismay of consumer firms.\nEven with speculations of a ban, it was evident that the basic groundwork was missing. There remains a lack of clarity on the definition of single-use plastic, with no guidelines issued regarding its usage or any clear plans forwarded to stop the usage or to provide for alternatives. While individual bans in different states have also not proved to be a solution, there is undoubtedly a need for phasing out the problematic plastics that cannot be recycled. Most single-use plastic products are consumed and discarded within a few minutes of their use. E-commerce giants and packaged food item companies are major users of such plastic.", "pred_label": "__label__POS", "pred_score_pos": 0.638446033000946}
{"content": "OR WAIT 15 SECS\nTo read a special commentary from Mark E. Rupp, MD, president of SHEA, CLICK HERE.\nThe Association for Professionals in Infection Control and Epidemiology (APIC) announced today that the organization, along with SHEA and the IDSA, have issued a letter to President Obama expressing concern over the current federal guidance surrounding the use of personal protective equipment (PPE) by healthcare workers in treating suspected or confirmed cases of 2009 H1N1 influenza.\nAccording to APIC’s statement issued today, the letter was precipitated by a re-evaluation of a study performed in China (MacIntyre, et al.) presented last week in which no significant differences were observed among healthcare workers wearing surgical masks or N95 respirators. Of note, the MacIntyre study was initially reported to show a significant benefit associated with the use of N95 respirators. This preliminary report was cited in the Institute of Medicine’s Sept. 3, 2009 Letter Report, which recommended the routine use of N95 respirators.\nAPIC reports that in its letter, it urged Obama and his administration to modify the guidance to reflect the position best supported by the available science – which is first-line use of surgical masks for routine H1N1 patient care. The letter also requests an immediate moratorium on OSHA’s requirement for healthcare facilities related to the use of N95 respirators in relation to H1N1 influenza. It was pointed out that permitting OSHA to continue to enforce a policy not grounded in science will force healthcare facilities to waste time and resources while working to comply with this requirement, rather than to enact measures that will significantly benefit patient care and healthcare worker safety during this national emergency.\nAdditionally, the communiqué expresses concern over the existing shortage of respirators, potentially precluding their use in situations where they are most needed. The letter detailed the advantages of surgical masks by providing appropriate protection for all routine patient encounters, and concludes by offering APIC's collective support in responding to the 2009 H1N1 pandemic.\nTo read the letter, CLICK HERE.", "pred_label": "__label__POS", "pred_score_pos": 0.5055210590362549}
{"content": "An unusual pillar stands within a storybook German forest. Just like the dense woodland surrounding it, the chunk of metal has inspired strange tales of its own.\nKnown as the Iron Man (der Eiserne Mann in German), this old iron pillar is an unexpected item to stumble upon. Strangely, the metal marker does not rust, despite withstanding centuries of rain.\nIt’s partially buried in the ground, making it look like the rectangular chunk of metal has always called this plot of earth home. However, that isn’t quite the case. The pillar has only stood within the forest since the early 18th century, pinpointing the spot where a few walking trails meet. According to one 17th-century document, it was previously used to mark a village boundary.\nIn the 1970s, metallurgical tests were conducted on the pillar, as people have long been curious about why it doesn’t rust. This investigation revealed it was made by someone pouring pig iron into an earthen trench, which is a medieval ironworking method.\nNaturally, given the marker’s odd appearance and mysterious history, stories have popped up surrounding it. Some tell tales of strange travelers who visit the marker in the night, while others say the structure is an out-of-place artifact that gives a glimpse of an unknown part of Germany’s past.", "pred_label": "__label__POS", "pred_score_pos": 0.5760613679885864}
{"content": "Rapidly evolving technology, emerging markets, an increasingly globalized development process, and evolving health policy reforms are presenting device manufacturers with unprecedented opportunities for valuable innovation. However, these trends are also creating significant challenges to current biomedical development frameworks. In response, the U.S. must sustain the industry’s entrepreneurial spirit, and maintain an environment that encourages innovation and access to novel devices.\nOn Wednesday, March 5, 2014, the Engelberg Center for Health Care Reform and the National Institutes of Health (NIH) held an all-day forum to discuss emerging issues in biomedical innovation. The panel sessions explored a number of challenges for developing novel medical devices that benefit patients, and for prioritizing medical device research that accommodates unmet medical need.\nOver the course of the day, manufacturers, regulators, payers, investors, patient representatives, and other stakeholders engaged in a thoughtful discussion on a number of topics. These topics included developing incentives to support investment in research and development; providing adequate infrastructure to support medical device development; and creating more efficient and transparent regulatory and reimbursement pathways. Attendees also discussed the need to actively engage patients in the decision-making process throughout the development pipeline.\nAgenda Director, Eunice Kennedy Shriver National Institute of Child Health and Human Development - National Institutes of Health Chairman and Chief Executive Officer - Medtronic plc Chairman and Chief Executive Officer - Edwards Lifesciences More Information\nTo subscribe or manage your subscriptions to our top event topic lists, please visit our event topics page.", "pred_label": "__label__POS", "pred_score_pos": 0.5405690670013428}
{"content": "Did you know that every home requires routine maintenance to stay in tip-top shape? Your DSLD home is no exception. Here we highlight 18 items on our Fall Maintenance Checklist that will help your DSLD home smoothly transition from summer into fall.Outdoor Maintenance\n1. Clean gutters, downspouts, and roof eaves to remove leaves and debris.\n2. Examine all exterior paint on your home and caulk and repair as needed.\n3. Inspect and maintain the flow of all ditches, culverts, and any drainage inlets or outlets. Inspect for erosion and repair as necessary.\n4. Before the first freeze, disconnect your exterior hoses and devices from hose bibs. If possible, shut off water to bib and drain.\n6. Oil all moving parts and tighten nuts and bolts on garage door and tracks. Check your garage door openers and sensors.\nHVAC Maintenance\n7. Replace or clean heating, ventilation, and air conditioning (HVAC) air return filters.\n8. Have an HVAC professional inspect and calibrate your heating system as the start of heating season approaches.\n9. Program your Honeywell WiFi thermostat* for heating settings to reduce energy usage.\n(*DSLD uses Honeywell WiFi Thermostats in our homes. For more information about these thermostats, visit our Customer Care page to see videos on how to operate and program your Honeywell WiFi Thermostat.)\nWasher/Dryer Maintenance\n10. Check the connection between your dryer and vent exhaust. Repair or clean as needed.\n11. Check your washing machine hoses and connections for cracks and leaks. Repair or replace as necessary per manufacturer.\n12. Check your dryer's vent exhaust for lint blockage. Clean as needed.\nIndoor Maintenance\n(DSLD Homes, Castine Pointe) 13. Check your range hood's charcoal filter. Replace or clean as necessary and repair as needed.\n14. Check caulk seals between your countertops and the walls. Repair as needed.\n15. Check thresholds, door sweeps, and weather stripping on exterior doors to maintain air tightness.\n16. Thoroughly check showers and all wet areas for mildew.\nFlorida-Specific DSLD Homes\n17. Test your sprinkler system to assure it is functioning properly and adjust or repair as needed.\n18. Flush out and drain the sprinkler system.\n*This checklist covers some basic necessary maintenance items for most homes. It is by no means all-inclusive. Some items may not be applicable for the type of home and home features you have. For full details, please consult all guides, warranties, and literature provided by DSLD Homes, as ell as the specific warranties and manuals for your home's various appliances.*", "pred_label": "__label__POS", "pred_score_pos": 0.5922026038169861}
{"content": "Connecting the Dots for Accountability: Civil Society Policy Monitoring and Advocacy Strategies Publication Type: Papers March 2016 | by the Transparency & Accountability Initiative\nIn the past decade, efforts to promote more open and accountable governance have proliferated. These endeavors have taken on many shapes and sizes, from international multi-stakeholder initiatives to community-level citizen action, and everything in between. Most often, these approaches have sought to leverage elements of transparency and information along with some form of citizen engagement or participation, with the goal of influencing government actions to be more responsive and accountable. But has the formula of transparency + participation = accountability really worked?\nCivil society organizations (CSOs) have often been at the front lines of these efforts, whether it be advocating for improved policies, monitoring government actions, mounting legal challenges to ensure accountability, or any number of other strategies. But do all these individual initiatives and approaches, many of which result in specific wins, really to add up to more than the sum of their parts?\nIn June 2015, researchers and practitioners from the global north and south met to discuss more strategic approaches to citizen-led accountability. Specifically, the workshop organizers sought to explore how CSO efforts could ‘connect the dots’ in ways that involve multiple actors, tools and tactics, and levels of governance. This report draws on the practical experiences and conceptual insights shared during the workshop. Key sections include:\nConceptual framework for connecting the dots Five concrete case study summaries of CSO strategies to connect the dots Workshop rapporteur’s report with insights organized around 8 key takeaway points\nThis report serves as a resource to those who want to address the challenge of isolated and fragmented transparency and accountability interventions that often do not strategically engage with the ecosystem of accountability actors, mechanisms and levels of governance to address the structural causes of corruption, impunity and poor service delivery, but rather more superficial symptoms.", "pred_label": "__label__POS", "pred_score_pos": 0.9626550674438477}
{"content": "Summary\nSelf-healing polymers can significantly extend the service life of materials and structures by autonomously repairing damage. Intrinsic healing holds great promise as a design strategy to mitigate the risks of damage by delaying or preventing catastrophic failure. However, experimentally resolving the microscopic mechanisms of intrinsic repair has proven highly challenging. This work demonstrates how optical micromechanical mapping enables the quantitative imaging of these molecular-scale dynamics with high spatiotemporal resolution. This approach allows disentangling delocalized viscoplastic relaxation and localized cohesion-restoring rebonding processes that occur simultaneously upon damage to a self-healing polymer. Moreover, frequency- and temperature-dependent imaging provides a way to pinpoint the repair modes in the relaxation spectrum of the quiescent material. These results give rise to a complete picture of autonomous repair that will guide the rational design of improved self-healing materials.", "pred_label": "__label__POS", "pred_score_pos": 0.7685819864273071}
{"content": "Subject essay: James von Geldern\nThe consumption of alcohol has deep cultural roots in Russia where it typically accompanied celebrations, signified hospitality, and enhanced bonding among acquaintances and friends. It also was a tremendous sources of revenue for the Soviet state which exercised a monopoly on its production and distribution. In 1979, for example, the state derived some 25.4 billion rubles in indirect taxes from the sale of alcoholic beverages which was more than were paid in income tax. Alcoholism, however, was a major scourge in Soviet society, linked to high rates of child-abuse, suicide, divorce (link), absenteeism, and accidents on the job, and contributing to a rise in mortality rates particularly among Soviet males that was detected in the 1970s.\nIn May 1985, less than two months after becoming General Secretary of the Communist Party, Mikhail Gorbachev launched a campaign against alcohol abuse, backing it up with a series of measures to reduce alcohol production and sales. These included limiting the kinds of shops permitted to sell alcohol, closing many vodka distilleries and destroying vineyards in the wine-producing republics of Moldavia, Armenia and Georgia, and banning the sale of alcohol in restaurants before two o’clock in the afternoon. To set a good example, official Soviet receptions both at home and abroad became alcohol-free. Exhorting Soviet citizens to abide by these measures, Gorbachev became known as the mineral’nyi sekretar’ (mineral-water-drinking secretary) rather than general’nyi sekretar’ (General Secretary).\nWhile the anti-alcohol campaign may well have resulted in a decline in alcohol consumption, it also precipitated a sharp rise in the production of moonshine (samogon) and, like Prohibition in the United States, an increase in organized crime. Instances of alcohol poisoning also rose, as hard drinkers turned to other, more dangerous, substances. No less serious was the decline in state revenues, which created a budgetary imbalance. This was overcome by resort to printing more money, which fueled inflation. For all these reasons, the campaign was abandoned after 1987.", "pred_label": "__label__POS", "pred_score_pos": 0.8740060329437256}
{"content": "Prime Source, NYSE Euronext’s independent asset valuation service, is pleased to announce the addition of Exchange Data International Limited (“EDI”) as a “closing prices” contributor to its service.\nEDI is a recognized provider of Securities Reference and Corporate Actions Data covering more than 420,000 bonds worldwide and nearly 90,000 listed equities; – tracking over 150 markets. EDI covers all major markets with a special emphasis on emerging markets.\nAs part of EDI’s ongoing commitment to support market transparency and provide reliable valuations metrics, they will be offering closing prices, via the Prime Source service, for a range of Stock Exchanges Worldwide including Hong Kong, Singapore, Arab Emirates, Morocco and Kenyan stock exchanges across financial products.\nPrime Source offers a one-stop service for independent valuations and is wholly owned by the NYSE Euronext exchange group, thereby avoiding potential conflicts of interest with respect to asset valuations. Prime Source can value a comprehensive set of products ranging from Vanilla to Term-Sheet trades and Structured Credit (Cash or Synthetic).\nPrime Source believes the addition of EDI’s closing prices will further strengthen its offering of valuation metrics to banks, hedge funds, fund administrators, auditors, asset managers and investors (risk management, compliance) as well as issuers. This announcement comes at a time of increasing demand for impartial valuation services, with regulators and institutional investors calling for greater transparency and independence in the valuation of complex securities.\nJonathan Bloch, Chief Executive Officer at EDI, says:\n“We are delighted to provide Prime Source with Worldwide Closing Pricing Data and contribute to this innovative and flexible valuation service. Prime Source offers a cost-effective solution to the pricing issues that have been at the core of the current financial crisis.”\nMarie-Hélène Crétu, CEO of Prime Source said,\n“We welcome Exchange Data International as a new and additional contributor to the Prime Source service. Exchange Data International’s closing prices, from many worldwide exchanges, will add tangible value to the depth of valuation services available via Prime Source. Through Prime Source, users can obtain the information they need to facilitate their valuation process in one single, independent source, allowing them to make an educated choice on pricing and valuation for complex and diverse instruments within their portfolio.”", "pred_label": "__label__POS", "pred_score_pos": 0.5253231525421143}
{"content": "Does your library offer services to support systematic literature reviews? Systematic reviews have long been common in the health sciences, and their popularity is growing in other disciplines. While a growing number of libraries provide services in this area, it can be challenging to collaborate with faculty and manage your time efficiently when working on multiple projects.\nIn this session, an independent consultant specializing in systematic reviews and a librarian from the United States Department of Agriculture share insights drawn from their experiences running effective systematic review services—even during a global pandemic—as well as practical tips for using EndNote™ to help you save time and stay organized once you’re up and running.\nLearn how you can:\n– overcome common challenges of starting and maintaining a systematic review service; – efficiently document the steps of your search process; and – save time managing and de-duplicating results sets.\nNote that you will receive two webinar recordings and respective presentations, as this webinar consists of two separate session.", "pred_label": "__label__POS", "pred_score_pos": 0.9911594390869141}
{"content": "The need for increased convergence in the decentralized processes for public enforcement of EU competition law has received much recent attention. Yet, this debate lacks a convincing explanation as to why the goal of effective enforcement warrants further harmonization. Focusing on fining practices for competition infringements, this article explores possible justifications to explain convergence; the legal or other means by which harmonization could be achieved; and the choice of converged practices that might be implemented. Whilst the strict necessity for convergence is less obvious, the evolving structure of decentralized enforcement would arguably benefit from increased alignment. Key concerns identified are the need to balance consistency with flexibility, and the reflection of an EU-wide consensus on fining practice.", "pred_label": "__label__POS", "pred_score_pos": 0.9578580856323242}
{"content": "Abstract\nThis paper offers new empirical evidence about the prospects of lower-income, US urban neighbourhoods during the 1990s. Using the Neighborhood Change Database, which offers a balanced panel of census tracts with consistent boundaries from 1970 to 2000 for all metropolitan areas in the US, evidence is found of a significant shift in the fortunes of lower-income, urban neighbourhoods during the 1990s. There was a notable increase in the 1990s in the proportion of lower-income and poor neighbourhoods experiencing a gain in economic status. Secondly, in terms of geographical patterns, it is found that this upgrading occurred throughout the country, not just in selected regions or cities. Finally, it is found that the determinants of changes in lower-income, urban neighbourhoods shifted during the 1990s. In contrast to earlier decades, both the share of Blacks and the poverty rate were positively related to subsequent economic gain in these neighbourhoods during the 1990s.\nASJC Scopus subject areas Environmental Science (miscellaneous) Urban Studies", "pred_label": "__label__POS", "pred_score_pos": 0.9908626675605774}
{"content": "June 19, 2020\nBy Uyghur Human Rights Project\nOn World Refugee Day 2020, the Uyghur Human Rights Project (UHRP) calls on the United Nations High Commissioner for Refugees (UNHCR) to address looming statelessness for Uyghurs outside of China.\nThe stated theme for World Refugee Day 2020 aims “to remind the world that everyone, including refugees, can contribute to society.”\nIn a recent report, Weaponized Passports: The Crisis of Uyghur Statelessness, UHRP uncovered how the denial of passport renewals at Chinese consulates is pushing Uyghurs overseas into de facto statelessness.\nThe deprivation of legal documentation impacts overseas Uyghurs’ capacity to find work, get married, undertake studies, and enjoy freedom of movement. In effect, these Uyghurs are denied the opportunity to contribute to society.\n“Uyghurs overseas need to have legal documentation. China’s refusal to provide Uyghurs with this documentation creates negative economic and social outcomes. There is no reason for the Chinese state to implement such measures except to control Uyghur bodies from beyond the borders of the People’s Republic of China,” said UHRP Executive Director Omer Kanat in a statement.\nMr. Kanat added: “UNHCR is mandated to support stateless individuals. It needs to work with states hosting undocumented Uyghurs so these vulnerable people can gain legal status and access social services and opportunities.”\nUyghurs around the world continue to suffer in immigration detention, like the 54 who have been held arbitrarily since 2014 in Thailand, as well as the countless others fighting for legal recognition in Turkey and elsewhere.\nIn 2014, UNHCR launched a campaign to end statelessness by 2024, accompanied by the hashtag #iBelong, that focused on the refugees of conflict. However, the #iBelong campaign overlooks the looming statelessness facing Uyghurs unable to secure passports at Chinese consulates.\nUNHCR’s lack of engagement with Chinese officials and counterparts from states hosting Uyghurs is incompatible with the goal to end statelessness in four years.\nUHRP calls on UNHCR to meaningfully engage with the theme of World Refugee Day 2020 and move towards ensuring the\nCopyright 2018 © Uighur Agency", "pred_label": "__label__POS", "pred_score_pos": 0.8049072027206421}
{"content": "The Superior Lamb Programme is designed for pet lamb rearing and early lambing farms (without milk replacer). The programme capitalises on the very high levels of efficiency in early life and allows the lamb to reach its genetic potential, removing any burden associated with rearing triplet lambs and offers an opportunity for producers to lamb earlier in the season where market opportunities are more favourable.\nThis unique rearing model focuses on critical developmental time points during early life that are crucial for the future success of your lamb or replacement ewe lamb. This programme focuses on early life metabolic programming and establishing an internal environment that optimises health, growth and productivity, delivering a lamb that achieves genetic potential. The individual elements of this protocol have been designed to address key developmental requirements;\nDelivering on these requirements, the Superior Lamb Programme takes advantage of the efficiency gains associated with optimal feed conversion rates, optimising the economic efficiency of this system. This concept is intensive, but the benefits multifaceted:\nWe recommend our Superior Lamb Starter Bundle to sustain 50 lambs for the first 2 months. This programme relies on the lamb having ad lib access to feed and fresh clean water at all times. Please refer to our specific production system programmes for more detail.\nThe chart details the Superior Lamb programme which outlines the products and timings required to deliver optimal production (product overview below). Please note that this programme relies heavily on the animal having ad lib access to fresh feed at all times.\nAnuStart Inmuprim Diter Inzarmilk Quickstart Lamb PapinLamb Econlamb\nAccreditations\nAnupro place quality assurance as a top priority with complete traceability of our entire product range. We participate in assurance schemes which have been developed to ensure optimum feed and animal safety.\nAs well as addressing the key elements of animal production systems; nutrition, housing and health, Anupro maintain an astute awareness of the environment and energy usage and all our processes are optimised for environmental sustainability.", "pred_label": "__label__POS", "pred_score_pos": 0.558754563331604}
{"content": "Rebecca Andruchow M.Ed (Candidate) Psychotherapy + Counselling\nHave you ever found yourself feeling stuck? As though each step you tried to take in life was as tedious as attempting to tap dance in quicksand? Are your thoughts and emotions sometimes so all-consuming that you feel caged in, and catch yourself longing for a sense of calm and balance? Do you often think things could be different, ‘If Only…’\nMy approach to the practice of psychotherapy is informed by the idea that Emotion is Motion, and that every client is the skillful architect of their own life. Too frequently, the constant cycling of our thoughts and feelings - often fed by pain, trauma and loss - end up hijacking our everyday behaviours and interactions within our interpersonal relationships until we are no longer aware who is actually the one behind the wheel of our psyche, steering us towards the choices we make. My goal is to help guide you to uncover and reconnect with your authentic self by empowering you to reclaim your place in the driver’s seat.\nI have extensive experience supporting and working with survivors of sexual violence and other significant experiences of trauma; those navigating challenges associated with depression, anxiety, grief and loss; as well as issues related to self-worth and difficulties in relationships. Because I work from a humanistic, person-centered perspective, I incorporate numerous different therapeutic modalities to curate a treatment experience rooted in the recognition that each individual’s healing journey is different and diverse from one another. I also recognize that it takes immense strength, courage and trust to share oneself vulnerably and openly, and aim to create a nurturing, compassionate and empathetic environment where you will feel seen, heard, and safe to fully and honestly express all aspects of yourself and your experiences.\nTogether, strengthened by the foundation of a strong therapeutic alliance, we will explore and piece together your unique story through mindful exploration, reflection, acceptance and integration of your thoughts, interpretations and emotions, to shift you from a place of surviving to one of thriving. I sincerely welcome and look forward to the opportunity to collaboratively work with you towards the growth and change you desire.\n----------\nRebecca holds an Honours Bachelor of Arts (with Distinction) in Writing and English Literature from Concordia University, as well as a Professional Counsellor Diploma from Rhodes Wellness College. Currently, she is completing the final year of a Master of Counselling Psychology at the University of Toronto, and will be registering with the College of Registered Psychotherapists of Ontario upon completion. As part of her ongoing psychotherapy training, Rebecca receives regular supervision from a Registered Psychotherapist which helps ensure she may provide the best possible support to all her clients, and is also in the process of completing training towards certification in Mindfulness-Based Stress Reduction (M.B.S.R).\nRebecca has previously worked as a mental health and wellness counsellor in private practice, as well as a therapist at the non-profit Vancouver Women’s Health Collective in Vancouver’s Downtown Eastside. She works from a trauma-informed, strengths-based, anti-oppressive framework, and specializes in working with survivors of sexual violence and trauma, as well as individuals struggling with anxiety and depression. Rebecca’s approach is always person-centered, and incorporates techniques drawn from Cognitive Behavioural Therapy, Emotion Focused Therapy, Relational Psychotherapy, DBT, ACT and other Mindfulness-based therapeutic approaches.\nTherapeutic Approaches\nEmotion-Focused Therapy\nCognitive Behaviour Therapy (CBT)\nMindfulness Based Cognitive Therapy\nRelational Psychotherapy\nAcceptance & Commitment Therapy (ACT)\nWorks with\nIndividual:\nAdults\nTeens 18+\nAvailability\nOnline & In-Person\nDaytime & Evening", "pred_label": "__label__POS", "pred_score_pos": 0.5237303972244263}
{"content": "\"I saw an ad saying a real estate professional will buy my house if it’s NOT sold in 90 days.\"\nShould I Be Wary?\nThis type of offer is a guaranteed sales agreement, and while there is nothing illegal or wrong with a real estate company offering this kind of arrangement, it is rarely the best option for consumers.\nIn a guaranteed sales agreement, a real estate brokerage agrees to buy a piece of real estate from a seller at a previously agreed upon price, if it hasn’t sold to someone else before a certain date. Only real estate brokerages can offer these agreements, not individual real estate professionals.\nIf you’re selling your home to buy another one, you may be interested in a guaranteed sales agreement for the home you own now. It could help you avoid owning two homes and paying two mortgages. A guaranteed sales agreement might give you the confidence to proceed with your new home purchase before selling your current one.\nWhat sellers need to keep in mind in these arrangements is that the real estate brokerage wants to minimize its risk.\nFor example, it’s rare that a guaranteed purchase price will be based on the property’s listing price or the property’s market value. In most cases, the brokerage calculates the guaranteed purchase price using a formula where legal fees, carrying costs, and commission on the resale are subtracted from the purchase price. This minimizes the brokerage’s risk, but it can also greatly reduce how much that seller receives for their home.", "pred_label": "__label__POS", "pred_score_pos": 0.9738420248031616}
{"content": "Second language listening in an academic context: lexical, perceptual, and contextual cues to word recognition\nWard, J. (2018)\nIt is advisable to refer to the publisher's version if you intend to cite from this work. See Guidance on citing.\nAbstract/Summary\nSecond language (L2) listening processes are generally thought to be under researched, especially in academic listening contexts, despite the importance of listening to the academic performance of international students in English-speaking countries. Additionally, research in the area is often not informed by theory from other fields. This research addresses both issues and investigates the word recognition processes of L2 listeners using methods informed by psycholinguistic theory. It explores the relationship between the words listeners’ report having heard and the evidence on which they rely, in the form of cues, within the speech signal. In addition, by ascertaining how much perceptual information is available to L2 listeners, the degree of their ability to build meaning and construct an accurate interpretation of the overall discourse can be implied, processes crucial in an English for Academic Purposes context. A paused transcription tasks is used, which is a method designed to induce the processes used in real-life listening. In this study, 171 university pre-sessional student participants listened to a recording taken from a pre-sessional listening course book which replicated a section of an academic lecture. Pauses were inserted irregularly into the recording at the end of target phrases. Whenever a pause occurred, participants reported immediately in writing the last four or five words heard. The outcome was a set of responses in the form of a series of words. Participants’ correct responses were analysed to establish the lexical features they may have relied on in their accurate word recognition processes, and their incorrect responses were analysed to establish which cues they made use of in their erroneous word recognition processes. This enabled insight into participants’ cognitive processes employed during the listening process. The findings were extensive and addressed several gaps in the knowledge of L2 listening. The major findings were i) word frequency was a key factor in accurate word recognition; ii) perceptual cues were more heavily relied on than contextual cues when listening broke down; iii) incorrect responses were informed by more than one single cue; iv) co-textual cues should be viewed separately from contextual cues; v) co-text is highly influential to L2 listeners; and vi) participants’ lack of confidence in their incorrect responses indicate they are behaving strategically. The findings support the notion that traditional teaching methods are not appropriate for L2 mid-level listeners, especially those preparing for academic study. Consequently, a call is made for a re-evaluation of listening training both in an academic context and more generally and suggestions for doing so are put forward.\nDownloads\nDownloads per month over past year", "pred_label": "__label__POS", "pred_score_pos": 0.5009127855300903}
{"content": "It has been challenging to find noteworthy sue cases for blockchain technology. A new report indicates the food industry should pay more attention to these distributed ledgers. Most people know blockchain technology due to its use in cryptocurrencies such as Bitcoin. However, the same technology can be utilized in systems that do not involve financial transactions as well.", "pred_label": "__label__POS", "pred_score_pos": 0.9999831318855286}
{"content": "Meningitis remains a universal public health challenge in countries around the world. The global number of deaths due to meningitis was estimated at around 300,000 in 2015.\nDeaths from meningitis and sepsis in children under the age of five were estimated to be higher than deaths due to malaria, not accounting the devastation from after effects.\nProgress in defeating meningitis lags behind other vaccine preventable diseases.\nThis project aims, for the first time, to produce a co-ordinated, global approach to defeating meningitis…..more", "pred_label": "__label__POS", "pred_score_pos": 0.9965643882751465}
{"content": "For the last 22 years I've been developing knowledge on human behaviour, how our thoughts influence how we act, and what actions we can take that influences our success, wellbeing, happiness and health. I am a practitioner of my own principles; I have never had a sick day from work, have never had a chronic illness or surgery, and have managed to resolve any acute illnesses within 48 hours - All this without taking any medication. I discovered early in life how perceptions of the mind can radically impact a person’s wellbeing. I have given over 100 courses in communication, thought processes, human perception, happiness and lifestyle, and trained thousands of people in the process.", "pred_label": "__label__POS", "pred_score_pos": 0.7297221422195435}
{"content": "TOKYO, Oct 20, 2020 – (JCN Newswire) – For the second consecutive year, Mitsubishi Heavy Industries, Ltd. (MHI) has been awarded a Silver rating for overall sustainability from EcoVadis, the independent French platform that regularly assesses corporate supply chains. At a time when the pursuit of the Sustainable Development Goals (SDGs) has become a global focus of universal concern, EcoVadis gave high marks to MHI Group for its initiatives in promoting sustainability throughout its supply chain in all four criteria categories: Environment, Labor & Human Rights, Ethics, and Sustainable Procurement.\nIn receiving a Silver rating, which is second only to Gold, MHI Group places within the top 24% of all companies evaluated by EcoVadis. Among manufacturers of general-purpose machinery, the rating puts MHI Group in the upper 16%.\nEcoVadis, working through its cloud-based platform, provides buyer companies with evaluative data pertaining to suppliers’ SDGs initiatives. To date, it has evaluated more than 45,000 companies worldwide.\nThrough the years, MHI Group has proactively undertaken diverse initiatives in each aspect of ESG (environmental, social, and governance) investment in a quest to contribute to sustainable social development. These include: reducing environmental burdens both internally and at its customer sites, promoting women’s empowerment, conducting social contribution activities, and strengthening corporate governance and information disclosure. These efforts have been recognized with the company’s inclusion in numerous ESG investment indices. Now, with receipt of a second Silver rating from EcoVadis, MHI has successfully reinforced its presence as a highly sustainable supplier in the global market.\nGoing forward, MHI Group, encouraged by receipt of EcoVadis’s high evaluation two years running, will further devote its resources to initiatives focused on the SDGs, pursuing continuous growth as a company trusted by its stakeholders and recognized as a leading contributor to sustainable social development.\nAbout Mitsubishi Heavy Industries, Ltd.\nMitsubishi Heavy Industries (MHI) Group is one of the world’s leading industrial firms. For more than 130 years, we have channeled big thinking into solutions that move the world forward – advancing the lives of everyone who shares our planet. We deliver innovative and integrated solutions across a wide range of industries, covering land, sea, sky and even space. MHI Group employs 80,000 people across 400 locations, operating in three business domains: “Power Systems,” “Industry & Infrastructure,” “Aircraft, Defense & Space.” We have a consolidated revenue of around 40 billion U.S. Dollars. We aim to contribute to environmental sustainability while achieving global growth, using our leading-edge technologies. By bringing people and ideas together as one, we continue to pave the way to a future of shared success.\nFor more information, please visit MHI’s website: https://www.mhi.com\nFor Technology, Trends and Tangents, visit MHI’s new online media SPECTRA: https://spectra.mhi.com\nCopyright 2020 JCN Newswire. All rights reserved. www.jcnnewswire.com", "pred_label": "__label__POS", "pred_score_pos": 0.510938823223114}
{"content": "High-Performance Lubricants Ensure Longer Bearing Life\nBearings—including ball, roller, and others used in critical applications—require high-quality oils and greases to ensure smooth-running performance. High-performance lubricants offer superior lubricity and consistent viscosity for bearings to perform in high loads, extreme temperatures, difficult-to-reach locations, or critical equipment.\nCritical equipment that can benefit from these high-performance bearing lubricants include:\nKrytox™ high-performance lubricants are made to accommodate the needs of such machines for the duration of their life.\nMeeting the Special Needs of Sintered Bearings\nSintered bearings are used whenever:\nLow noise levels are required Loads are variable Little space is available\nThese bearings consist of a pressed metal powder whose pores are impregnated with a lubricant. This impregnating oil ensures the bearings are permanently lubricated.\nWhether a sintered bearing is metal, ceramic, or polymer-based, Krytox™ performance lubricants retain their viscosity and lubricating properties in high-temperature, high-pressure environments, while consistently outperforming hydrocarbon-based lubricants.\nBenefits Abound\nKrytox™ synthetic greases and oils used in bearings and sintered bearings provide longer-lasting lubrication, reducing relubrication frequency. This not only reduces operating costs due to less maintenance, but it also minimizes waste and environmental impact.\nKrytox™ high-performance lubricants applied to bearings and sintered bearings provide:\nSuperior film-forming capability: The oil forms a thicker boundary layer, reducing wear. Extreme resistance to oxidation: Krytox™ oil, combined with advanced high-efficiency polytetrafluoroethylene (PTFE) thickener, will not oxidize, gum up with age, or break down with shear. Extreme temperature performance: Lubricants will not break down in the high temperatures of electric motor applications (can operate in a temperature range of -75 to 350 °C [-103 to 662 °F]). Optimal stability: Krytox™ lubricants are water-resistant, nonflammable, and chemically inert. Fill-for-life potential: There is typically no need to relubricate bearings during a product's lifetime. Corrosion resistance: These additives resist corrosion and rust during storage and in wet environments.", "pred_label": "__label__POS", "pred_score_pos": 0.986646294593811}
{"content": "On October 13, the Financial Crimes Enforcement Network (“FinCEN”) issued a COVID-19-related Advisory “to alert financial institutions to unemployment insurance (“UI”) fraud observed during the COVID-19 pandemic.” It is the fourth in a series of Advisories related to financial crimes arising from the pandemic (we covered previous Advisories on medical scams, imposter and money mule schemes, and cyber-enabled crime). This latest Advisory “contains descriptions of COVID-19-related UI fraud, associated financial red flags indicators, and information on reporting suspicious activity.”\nCOVID-19-Related UI Fraud\nNot surprisingly, as the level of UI claims has surged in light of the pandemic and the ensuing economic stress, FinCEN reports that it and financial institutions have detected “numerous instances” of UI fraud. The Advisory lists several representative types of UI fraud: UI applicants claiming to have worked for fictitious companies or creating fictitious work records, collusion between employers and employees to enable an employee to receive simultaneously a UI payment and a paycheck, and applicants inflating wages to receive a higher UI payment.\nTwo additional types of fraud described in the Advisory warrant mention. First, the Advisory warns that state employees may use their credentials to alter UI claims, approve otherwise unqualified UI applicants, direct UI payments to accounts not on the UI application, or increase the approved UI payment amount. However, the Advisory’s red flags provide little guidance to financial institutions on how to identify or distinguish “insider” UI fraud from its ilk.\nSecond, the Advisory warns that UI applicants may submit to the state stolen or forged identification documents in their UI application to take over an account eligible for UI payments. The Advisory’s reference to FinCEN’s July 30th Advisory on pandemic-enabled cybercrime complicates a financial institution’s obligations to detect these schemes. As we previously commented, detecting cybercrime perpetrated during COVID-19 is “perhaps easier said than done.” That is particularly true in the UI fraud setting, where the perpetrator has already fooled state authorities into making UI payments, which are only a portion of hundreds of thousands of weekly UI claims.\nUI Fraud Red Flags\nNevertheless, the Advisory, in keeping with FinCEN’s risk-based approach towards BSA compliance, lists red flags for financial institutions to consider along with “all surrounding facts and circumstances before determining if a transaction is suspicious or otherwise indicative of potentially fraudulent activities related to COVID-19.”\nAccounts held at the financial institution show suspicious UI payment and withdrawal signs, including: out-of-state UI payments; multiple UI payments within a single disbursement window; UI payments to someone other than the accountholder; UI payments collecting at the same time as regular work earnings; numerous deposits that indicate they are UI payments made to someone other than the accountholder; and UI payments made with greater frequency than similarly situated customers. The customer withdraws UI funds in a lump sum by cashier’s checks, by purchasing a prepaid debit card, or by transferring the funds to out-of-state accounts. The customer’s UI payments are quickly wired to foreign accounts, particularly to countries with weak anti-money laundering controls. The customer receives or sends UI payments to a peer-to-peer (P2P) application or app. The funds are subsequently transferred to an overseas account in a manner inconsistent with the spending patterns of similarly situated customers. Individuals quickly withdraw disbursed UI funds for “bill payments” to individuals instead of businesses, with some individual payees receiving multiple online bill paychecks over a short time period. The IP address associated with logins for an account conducting suspected UI-fraud activities is geographically distant from the customer’s address or where the UI payment originated. Individuals transfer UI funds into suspected shell/front company accounts. A single, web-based email account is associated with multiple accounts receiving UI payments at one or more financial institutions. A newly opened account, or an account that has been inactive for more than thirty days, starts to receive numerous UI deposits. After a financial institution requests documents to verify customer’s identity, the customer provides incorrect or forged documents. A financial institution’s due diligence investigation reveals that the customer does not have a history of living at, or being associated with, the address to which the UI check or UI debit card is sent, or within the geographical area in which the UI debit card is being used. SAR Reporting\nConsistent with prior Advisories relating to fraud exacerbated by COVID-19, the Advisory provides specific instructions for filing a Suspicious Activity Report (“SAR”) when financial institutions suspect UI fraud.\nSARs should include the key term “ COVID19 UNEMPLOYMENT INSURANCE FRAUD FIN-2020-A007” in SAR field 2 and in the narrative. Financial institutions should select SAR field 34(z) (Fraud-other) when reporting such fraud and specifically denote whether the same is an “unemployment fraud.”", "pred_label": "__label__POS", "pred_score_pos": 0.7660516500473022}
{"content": "In recent years, legal cannabis-based products containing cannabidiol (CBD), have become more available. Could these help stroke survivors to cope with problematic effects of stroke?\nAphasia is a long-term condition and many people will continue to need support for several years after its onset. However, with the right tools and support, even someone with severe aphasia can continue to communicate effectively.\nA guide for family, friends and carers of people who have had a stroke, from the Stroke Association. Packed with information about the emotional impact of stroke, rehabilitation and recovery, and the support available to carers.\nThis guide provides information about why someone might not survive a stroke, and the emotional impact on family and carers. Plus a list of useful resources to help you with practical issues such as how to register a death, finding professional counselling services, and support for bereaved children.\nBroadcaster, author and stroke survivor Andrew Marr is supporting a nationwide search for stroke survivors to enter the Stroke Association’s Life After Stroke Awards (LASA) 2016.\nHow aphasia may affect your mood and emotions.", "pred_label": "__label__POS", "pred_score_pos": 0.8523784279823303}
{"content": "I like the SAP Opening Keynote with Bill McDermott, CEO of SAP SE from 2017 SAPPHIRE NOW because of its focus on The Urgency of Doing.\nIn fact, I had come to a similar conclusion and inspired by the excellent blog SAP Leonardo “Reloaded” – Unifying People, Process and Technology to Enable Digital Transformation by my colleague and SAP Mentor Owen Pettiford I would like to share this with you.\nIt was back in 2014, preparing for a roundtable event, when I realized that some of the then hype concepts or at least variations of them had in fact been around for a while:\nThis made me suspicious and I started comparing some of the then current SAP messaging around business versus IT challenges with their counterparts a decade ago:\nInterestingly, at least to me, it seemed as if we were still facing similar challenges than a decade ago! Had there been no progress or is it just the nature of business to ever present us with new frontiers?\nTruly intrigued, I started comparing the suggested solutions from SAP both then and again a decade ago:\nThe result was enlightening. An increasingly capable stable core at lowest cost, then SAP HANA and a decade ago SAP NetWeaver, seemed to have been the common pattern for success by unleashing innovation to offset an ever-increasing speed of change.\nAt 2017 SAPPHIRE NOW, this knowledge where SAP have been coming from, helped me to understand what they are aiming for and The Urgency of Doing. In a world of ever accelerating change, the stable core had to become digital:\nHowever, as we have seen, the availability of an increasingly capable stable core at lowest cost does not solve any challenges unless we put it into action:\nIn my experience, there is no silver bullet, no magic wand or lucky ancient bracelet. To say it with Erich Kästner, “Actions speak louder than words.” (“Es gibt nichts Gutes, außer man tut es.”).\nTherefore, in my opinion, don’t wait for the next stable core or improved version of it, but leverage what is available now and put it into action. Ask yourself: Why not now?", "pred_label": "__label__POS", "pred_score_pos": 0.5891969203948975}
{"content": "NCASE Resource Library Featured Resources\nThis publication features some of the best resources, including webinars, briefs, and toolkits, available in the online NCASE Resource Library, developed for both practitioners and system builders.\nThese selected resources, curated by NCASE, offer ideas and information for OST system leaders to support recovery from COVID-19.\nThe NCASE Out-of-School Time Professional Development System-Building Toolkit was designed to assist states as they build professional development systems inclusive of school-age providers.\nSearch for Resources ? Search Results Filter By Reset Selections Expand All Filters Topics Resource type Publisher Search Results Filter By\nThis resource offers information on supporting children’s emotional well-being during the COVID-19 public health crisis. It includes recommendations for how to talk to children about the virus and how to promote emotional health through reassurance, routines, and regulation. It also includes links to key organizations that can support children, families, and providers.\nThis toolkit is designed to help state system planners from early childhood, Head Start, and schools create plans for a successful transition to kindergarten. It includes materials like a transition and alignment summit guide, a questionnaire on transition practices, and research and resources on why transition matters and how to engage families.\nThis toolkit is designed to support states and territories in designing a policy approach to promote social emotional development and reduce the likelihood of expulsion and suspension.\nThis national study explores how low-income children's access to early childhood education might differ from their higher-income peers and how child care subsidy policies can close the gap. The study assigned states to one of five profiles based on a package of subsidy policies to produce findings about which packages provide equity in access to high quality programs.\nThis self-assessment tool is designed to help providers evaluate how to be more responsive in serving children and families experiencing homelessness. It includes indicators and related resources on how to identify and support families, removing barriers, responding to family needs, strategic collaboration, and collecting data. This resource supports resilience.\nThis report describes and presents the demographics of immigrant and refugee children who will enter the United States in 2016, including: numbers of children, countries of origin, legal designations, threats to well-being before and after immigration with regard to family stability, health, schooling, and economic security.\nThis comprehensive guide on preventing child abuse and neglect uses a strength-based framework for protecting children and strengthening families and community networks. Most valuable are the short tip sheets designed for parents in Chapter 5; they build competencies on a wide range of topics and are presented in Spanish as well as English.\nThis document provides links to teaching resources, training models, publications, and other resources to assist child care providers and families as they help children recover from exposure to a natural disaster or other traumatic event. It includes links to relevant federal agencies, national organizations, and additional publications.\nThis report explores why libraries are well positioned to be allies in increasing family engagement. The strategies shared come from a review of the literature, a survey of library directors, and a learning community of librarians.", "pred_label": "__label__POS", "pred_score_pos": 0.9460694789886475}
{"content": "Keep the door to when a cat has allergies bedroom shut when you are gone, many people don’t even realize they’re suffering from this. You can dangle your hand to see if he rubs up against it, sorry that the video wasn’t helpful. These shots are made from a serum of cat allergens and injected into the upper arm at incrementally increasing doses over a number of weeks until you reach a maintenance dose, both can recommend a good shampoo to remove allergens while still being gentle on the skin. Once the allergies are diagnosed, leave the building at once. When it comes to pollen, leading to weight loss. A central air cleaner, and so is your beloved feline friend. Keep in mind that even if you don’t have an actual cat allergy, about Caitlin Seida: Owned by three cats and two dogs, and completing treatment can take years.\nSuch as Allerpet cat Nature’s Miracle Allergen Blocker; thus reducing has, it can allergies stressful for both you and your cat if they have a food a. Once an allergen has been determined, when Are the Symptoms of Cat Allergies? Consider replacing wall, unscented litter to see if that helps. And ask if the cat may be returned — even if you’ve never been allergic to anything else before.\nCertain dander-reducing solutions and shampoos, such as Allerpet and Nature’s Miracle Allergen Blocker, cleanse your cat and can remove some allergy-causing dander. Otherwise, thoroughly vacuum your carpet on a regular basis. After bathing, the levels of Fel d 1 on cat skin and fur return within two days of bathing.\nBy using our site, if keeping your cat is putting your health, next he performed a skin scrape and Wood’s light exam to test for mites. By using our site, your cat could be allergic to other things besides pollen and flea saliva. Trout and sardines either. Your when a cat has allergies might prescribe an anti, if you anticipate issues with your schedule ask your vet for when a cat has allergies solutions. Beavis is an only cat who stays indoors all the time, notices more clients seeking relief for their feline friends when the high pollen count rises. If your cat isn’t already an indoor, allergy shots are not always effective, it may worsen your cat’s asthma.", "pred_label": "__label__POS", "pred_score_pos": 0.5954070091247559}
{"content": "Abstract\nBackground-T-wave alternans (TWA) increases before ventricular tachycardia (VT) or fibrillation (VF), suggesting that it may warn of VT/VF in implantable cardioverter-defibrillator patients. Recently, we described a method for measuring alternans and nonalternans variability (TWA/V) from electrograms (EGMs) stored in implantable cardioverter-defibrillators before VT/VF. The goal of this prospective, multicenter study was to determine whether EGM TWA/V was greater before VT/VF than at baseline. Methods and Results-We enrolled 63 implantable cardioverter-defibrillator patients. TWA/V was computed from stored EGMs before spontaneous VT/VF and from sequential windows of 8 pairs of beats using 4 different control recordings: baseline rhythm, rapid pacing at 105 bpm, segments of ambulatory Holter EGMs matched to the time of VT/VF episodes, and EGMs before spontaneous supraventricular tachycardia. During follow-up, 28 patients had 166 episodes of VT/VF. TWA/V was greater before VT/VF (62.9±3.1 μV; n=28) than during baseline rhythm (12.8±1.8 μV; P<0.0001; n=62), during rapid pacing (14.5±2.0 μV; P<0.0001; n=52), before supraventricular tachycardia (27.5±6.1 μV; P<0.0001; n=9), or during time-matched ambulatory controls (12.3±3.5 μV; P<0.0001; n=16). By logistic regression, the odds of VT/VF increased by a factor of 2.2 for each 10-μV increment in TWA/V (P<0.0001). Conclusions-In implantable cardioverter-defibrillator patients, EGM TWA/V is greater before spontaneous VT/VF than in control recordings. Future implantable cardioverter-defibrillators that measure EGM TWA/V continuously may warn patients and initiate pacing therapies to prevent VT/VF.\nKeywords implantable cardioverter defibrillator T-wave alternans tachyarrhythmias ASJC Scopus subject areas Physiology (medical) Cardiology and Cardiovascular Medicine", "pred_label": "__label__POS", "pred_score_pos": 0.850530743598938}
{"content": "“Our experience working with the team at Lippincott was extraordinary. They expertly guided us through a process to land on a brand platform that completely energized our network and its members.”Network Support Team Communications Manager\nRooting a brand in its purpose to improve oral health for all\nThe Oral Health 2020 network, an interconnected network of national, state, and community-based change agents, was at a significant inflection point. A multi-year effort to unify its growing network of 1,200 members and expand its impact was facing increased national visibility, greater autonomy from its parent organization, and a pressing need to clarify its purpose and inspire a movement.\nFollowing our rebranding of the network’s parent organization, DentaQuest, Lippincott partnered with Oral Health 2020 to help navigate this moment of change. The project began by codifying the brand purpose and articulating a new brand platform, and culminated in a new name and visual identity.\nFor its brand strategy, we looked to the core issue the network sought to solve. Oral health is a vital component of overall health, and people across the country are suffering from preventable oral health issues due to inaccessibility to proper care. Through a series of workshops, together we landed on a purpose: to\ncatalyze a network to take on America’s oral health challenges, so that everyone has an equitable chance to thrive.\nWith this purpose as an anchor, the name and visual system took shape. The new name, OPEN (Oral Health Progress and Equity Network) strikes a balance between pragmatic and visionary, referring to the network’s commitments to understand diverse perspectives, welcome new members and unlock opportunities.\nThe visual expression, starting with a new logo, reinforced the purpose. The open “E” of the logotype speaks to their collective action and growth. A vibrant color palette and purposeful typeface give the identity confidence, while a layered illustration style and honest imagery show their collaboration and inclusivity. A highlight device and bold information graphics emphasize their knowledge and support their mission.\nArmed with its new brand, OPEN is well-positioned to reshape oral health across the country, bring lasting change, and unify its expanding network to fully harness its potential.", "pred_label": "__label__POS", "pred_score_pos": 0.7074624300003052}
{"content": "The Peace of Wild Things by Wendell Berry\nWhen despair for the world grows in me\nand I wake in the night at the least sound in fear of what my life and my children’s lives may be,\nI go and lie down where the wood drake\nrests in his beauty on the water, and the great heron feeds. I come into the peace of wild things who do not tax their lives with forethought of grief,\nI come into the presence of still water.\nAnd I feel above me the day-blind stars waiting with their light. For a time I rest in the grace of the world, and am free.\nI return to this poem to remind myself to rest in the grace of the world. We are all living through the fear, anger, and sadness of the coronavirus. Being separated from family, friends, and work has been difficult as we continue to practice social distancing and wearing masks. This past week has been the most tumultuous for me. Such grief and sadness abound as we marked the 100,000 death in our country due to Covid 19.\nWe also are witnessing the cultural wars that divide our country. First, clashes over something as simple as wearing a mask. Then this past week we are again confronted with the racial divide in our country. Another black man murdered by police in Minneapolis, MN. We are witnessing so many deep divides in our country. How can each of us begin to bridge the gap? It will begin by reaching out to one another with an open heart, compassion, and empathy, plus a deep desire to listen to each other.\nI woke this morning and knew I had a choice. I could stay angry and grief-stricken or I could choose to reside in gratitude. Returning to gratitude, I felt my whole body unwind. I have so much to be grateful for. My friends and family, my clients who entrust me with their stories, my garden filled with spring flowers, and the birds that grace my feeder. These are what bring me joy in life. When I reside in gratitude I am present to all that surrounds me.\nI will not bury my head in the sand. I’ll continue to take action when I feel others are being unjustly treated, but I choose not to linger there. I choose to return to gratitude, joy, and hope. May you choose to reside in gratitude for your health and well-being as you move through these difficult times our country is facing.\nThis is a modified version of an earlier post.Photo by David Dibert from Pexels", "pred_label": "__label__POS", "pred_score_pos": 0.6058905124664307}
{"content": "Abstract\nWe develop a framework where mismatch between vacancies and job seekers across sectors translates into higher unemployment by lowering the aggregate job-finding rate. We use this framework to measure the contribution of mismatch to the recent rise in US unemployment by exploiting two sources of cross-sectional data on vacancies, JOLTS and HWOL. Our calculations indicate that mismatch, across industries and three-digit occupations, explains at most one-third of the total observed increase in the unemployment rate. Occupational mismatch has become especially more severe for college graduates, and in the West of the United States. Geographical mismatch unemployment plays no apparent role.\nASJC Scopus subject areas Economics and Econometrics", "pred_label": "__label__POS", "pred_score_pos": 0.6746844053268433}
{"content": "Is PTSD Covered by Workers’ Compensation?\nPost-traumatic stress disorder (PTSD) is a serious mental health issue that sometimes occurs after individuals experience or witness a distressing or life-threatening event. Symptoms of PTSD include frequently reliving the incident (having bad dreams, nightmares, etc.), the desire to avoid situations that might provide a reminder of the event, negative feelings such as guilt or shame, constant jitters or being on the lookout for danger, depression and the inability to concentrate. While these symptoms typically occur soon after the traumatic event, they may not appear for several months or even years.\nWhile PTSD is most often associated with military combat veterans, it can also occur in the civilian workforce. Professionals who are most susceptible to the onset of PTSD symptoms include police officers and emergency medical workers who witness disturbing incidents on almost a daily basis. However, specific workplace incidents can also trigger PTSD symptoms — consider the construction worker who sees a coworker falling from heights, a woman who is the victim of sexual assault while at work or a school teacher who witnesses a mass shooting.\nPTSD and Mental Health Workers’ Comp Claims\nWorkers’ comp insurance can provide financial benefits such as replacement of lost wages and payment of medical bills if an employee is unable to work due to a job-related accident or illness. While workers’ comp typically applies to physical injuries, it may also provide coverage for mental disorders. Mental illness-based workers’ comp claims can fit into the following categories:\nPhysical-mental —When a physical injury or illness leads to the development of a mental disorder such as depression or anxiety Mental-physical —When a work-related mental disorder leads to the onset of a physical issue Mental-mental —When a psychological stimulus manifests as a mental illness, which is exemplified by PTSD Receiving Workers’ Comp Benefits for PTSD Can Be a Challenge\nWhile the workers’ comp laws in many states permit the payment of benefits for PTSD, they can be challenging to obtain. You typically must be able to demonstrate that you have experienced a situation where you feared for your life or experienced a traumatizing event that could be considered extraordinary in comparison to your “normal” working conditions. You must also demonstrate that the resulting symptoms are hindering your ability to work. A formal PTSD diagnosis from a company-approved psychiatrist or psychologist is also required.\nMany employers are highly skeptical of PTSD-related workers’ comp claims. Expect scrutiny from your employer and its workers’ comp insurance carrier, as they will look for any reason to limit your benefits or deny your claim. The insurance company’s investigators will likely delve into your personal and medical history to uncover any information that could discredit your claim.\nIf you are in Kansas or Missouri and need help with a PTSD-related workers’ comp claim, the expert legal professionals at Phalen Law Firm may be able to increase your odds of a successful outcome. We also offer free initial consultations.", "pred_label": "__label__POS", "pred_score_pos": 0.9550994634628296}
{"content": "Another Report Finds Anti-Muslim Bias in British News Media26 Aug 2020\nCoverage of terrorist attacks in the British news media has been “consistently inconsistent” and often with an anti-Muslim bias. These are the findings of the Centre for Media Monitoring (CfMM). The CfMM, which is part of the Muslim Council of Britain (MCB), published its report on the media coverage of terrorist attacks earlier this week.\nThe report found that terms such as “terror” and “terrorism” are used most frequently when reporting on “Islam” and “Muslim/s” in British news media. Many of the same outlets are unwilling to use “terror” or “terrorism” when the perpetrator was identified as “far-right”, “neo-Nazi” or “white supremacist”.\nThe report, which was published to coincide with the sentencing hearing of the perpetrator of the Christchurch mosque attacks in 2019, noted that the disparity has reduced in recent years but remains.\n“Terrorism is disproportionately the most recurring theme in British media when reporting on Muslims”\nThe CfMM report, which was released on Monday, noted that the association of “Muslims” and “terrorism” in news coverage has been a recurring theme since the 9/11 attacks.\nThe report adds to the findings of a previous report from 2018 which analysed 10,931 online news articles. Its findings were that a quarter of the pieces with an identifier of Muslims or Islam were coverage of terrorism or extremism. Further findings showed that between 2000 and 2008, a third of the articles in print media linked Muslims to terrorism. It warned that such reporting had a cumulative effect of creating the perception of a link between Islam and terrorism while leaving Muslims less likely to trust print media over the perceived biases.\nThe new report finds that words identifying Muslims or Islam are placed more frequently alongside terms such as “terror”, “terrorist” or “terrorism” in contrast to the when a perpetrator is described as of “far-right” or “white-supremacist”.\nThis is especially apparent between 2015 and 2019 when over half the references to “terror” and related terms were used alongside references to “Islam” and related terms. This is almost nine times more than terms relating to “terror” referencing “far-right” or “white-supremacist”.\nIn general, researchers found that members of the press were more likely to use “terrorism” and related terms if the perpetrator of an attack was Muslim.\nA case study was presented with two incidents that took place in 2018: In August 2018, a Coventry resident, Salih Khater, reportedly drove at cyclists and police officers outside the Houses of Parliament. Khater said he was lost, panicked and lost control of his car. His online history or other activity showed no indication towards radicalisation or extremism. Despite this, newspapers were quick to report the incident as a terror attack.\nA month later, a driver targeted Muslim worshippers at Al-Majlis Al-Hussaini Islamic Centre in Cricklewood, with the driver shouting “a tirade of Islamophobic and racist abuse.” Despite the deliberate and targeted nature of the attack, the press refrained from calling it a terror attack, with Daily Mail referring to “racist attack” and the Daily Express referring to it a “hit-run”.\nCfMM’s report also warned that mainstream press has often failed to challenge pro-white supremacist and anti-Muslim rhetoric during the coverage. Furthermore, it finds that online news sites, such as the Mail Online, often referred to “Allahu Akbar” as a shorthand for motivation for terrorism committed by individuals of a Muslim background.\nThe disparity in bias reporting has reduced but remains\nThe CfMM report found that from 2019 onwards, news outlets took some effort to improve coverage, and that two events marked that shift. The first was the terrorist attack in Christchurch, New Zealand, in which a far-right, white supremacist killed 51 Muslim worshippers. The second was an attack in El Paso, United States, in which a far-right extremist killed 22 people, while specifically targeting Hispanics.\nThese two events appear to have resulted in a re-evaluation of how these topics are covered in the British press. As a result, terms relating to “terrorist”, “terrorism” or “terror” were used alongside “Islam” or “Muslim” only twice as often as “far-right”, “neo-Nazi” or “white supremacist”. The report also found that mainstream British press outlets including the BBC, ITV and Sky have all shown much greater vigour exploring the topic of white supremacy. While a significant improvement, the disparity in coverage remains stark.\nThe report made a number of recommendations to help UK news outlets improve their coverage. Among other things, it called for: a transparent and public definition of terrorism that is consistently applied and used only when relevant facts are established; for journalists to avoid uncorroborated witness statements and making bogus links between terrorism and normal Islamic practices, such as attending a mosque; to avoid headlining the term “Allahu Akbar” as shorthand for motive; and called on outlets to avoid platforming far-right and white supremacist voices, “except in those circumstances where their views are contextualised and can be sufficiently challenged”.", "pred_label": "__label__POS", "pred_score_pos": 0.621471643447876}
{"content": "Aminoacyl-tRNA synthetases catalyze the attachment of amino acids to their cognate tRNAs. A link was recently established between protein biosynthesis and cytokine signal transduction. Human tyrosyl-tRNA synthetase can be split into two fragments, each of which has a distinct cytokine function. This activity is specific to the human enzyme. It is absent in the enzymes from lower organisms such as bacteria and yeast. Here, yeast tyrosyl-tRNA synthetase (TyrRS), which lacks cytokine activity, was used as a model to explore how a human tyrosyl-tRNA synthetase during evolution acquired novel functions beyond aminoacylation. We found that a rationally designed mutant yeast TyrRS(ELR) gained cytokine function. The mutant yeast enzyme gained this function without sacrifice of aminoacylation activity. Therefore, relatively simple alteration of a basic structural motif imparts cytokine activity to a tRNA synthetase while preserving its canonical function. Further work established that mutational switching of a yeast protein to a mammalian-like cytokine was specific to this synthetase and not to just any yeast ortholog of a mammalian cytokine.", "pred_label": "__label__POS", "pred_score_pos": 0.929905116558075}
{"content": "Antara, Alexandra Helena, Jakarta – The Witness and Victim Protection Agency (LPSK) urged the House of Representatives (DPR) to consider the sexual violence elimination bill or RUU PKS as the priority that must be deliberated in the National Legislation Program in 2021.\nLPSK argued that the ratification of the bill as a product of legislation is extremely urgent. \"We encourage the bill to be included in the priority of the DPR discussion in 2021,\" said LPSK Deputy Chairperson, Livia Iskandar in her statement on Tuesday, October 6, 2020.\nLivia said the problem was the increasing number of sexual abuse cases. The LPSK noted that at the end of September 2020, there were 223 witnesses and victims who submitted requests for protection in cases related to sexual harassment.\nIn 2018, LPSK protected 401 witnesses or victims, and the number increased to 507 in 2019. However, during the legal process, such cases were often deemed lacking the elements of a criminal act.\nTherefore, Livia considered that it was vital to issue a law that was able to reach any form of sexual abuse cases. \"In many cases, as the legal process cannot be resumed, victims often get counter-attacks from perpetrators, such as counter reports,\" she added.\nThe National Commission on Violence against Women (Komnas Perempuan) commissioner Veryanto Sitohang also urged the same issue given the high number of sexual harassment cases.\n\"Throughout 2011 to 2019, there were 46,698 cases of sexual violence that occurred in the personal and public domains,\" said Veryanto.", "pred_label": "__label__POS", "pred_score_pos": 0.5497138500213623}
{"content": "Ovum Report: How Quadient is evolving from CCM into CXM\nCustomer experience management (CXM) is a major focus area for digital transformation by enterprises across all industries and sectors as power has shifted towards the customer, who has more choice and greater access to products and services from around the world.\nGlobalization led to commoditization, making it harder for businesses to stand out from the crowd. Native commerce ecosystem leaders, such as Amazon, Alibaba, and disruptors such as Uber, AirBnB,and others, have driven customer expectations for convenience to new heights threatening established businesses and reducing the window of opportunity to transform in order to keep up.\nAgainst this volatile and uncertain background, the race is on to differentiate through the quality of experience delivered to customers throughout their many and varied journeys across digital and physical landscapes.\nOvum's research outlined in this report, shows that progress has stalled and that most enterprises are struggling to make any headway. They need help. The CXM drive has also attracted thousands of vendors, large and small, that seek to carve out a share of the market. While the opportunity is vast, vendors must decide where they can play and where they must partner.\nQuadient, with a rich heritage in customer communications management, has firmly nailed its colours to the CXM mast, and this report outlines their journey and the challenges it faces to deliver on its vision: to be the driving force behind the world's most meaningful customer experiences.", "pred_label": "__label__POS", "pred_score_pos": 0.5014753341674805}
{"content": "June 2, 2011\nWhile publicly available data can provide valuable information on broad housing market conditions in the St. Louis region, these sources do not pinpoint regional, county, or neighborhood house-price trends. Even expensive proprietary data may not be satisfactory. Additionally, it does not help that the most widely followed housing indices in the U.S., the S&P/Case-Shiller Home Price Indices, do not include the St. Louis Metropolitan Statistical Area (MSA.)\nTo this end, the Federal Reserve Bank of St. Louis and the Public Policy Research Center of the University of Missouri—St. Louis recently held a first-of-its-kind housing data conference targeted specifically for the St. Louis MSA at the St. Louis Fed's Gateway Conference Center.\nQ&A | Dr. William Emmons, assistant vice president and economist, St. Louis Fed (8:46)", "pred_label": "__label__POS", "pred_score_pos": 0.9654884934425354}
{"content": "Atlantic Multidecadal Variability and the U.K. ACSIS program\nSutton, R. T., McCarthy, G. D., Robson, J., Sinha, B., Archibald, A. T. and Gray, L. J. (2018)\nIt is advisable to refer to the publisher's version if you intend to cite from this work. See Guidance on citing.\nTo link to this item DOI: 10.1175/BAMS-D-16-0266.1\nAbstract/Summary\nAtlantic multidecadal variability (AMV) is the term used to describe the pattern of variability in North Atlantic sea surface temperatures (SSTs) that is characterized by decades of basinwide warm or cool anomalies, relative to the global mean. AMV has been associated with numerous climate impacts in many regions of the world including decadal variations in temperature and rainfall patterns, hurricane activity, and sea level changes. Given its importance, understanding the physical processes that drive AMV and the extent to which its evolution is predictable is a key challenge in climate science. A leading hypothesis is that natural variations in ocean circulation control changes in ocean heat content and consequently AMV phases. However, this view has been challenged recently by claims that changing natural and anthropogenic radiative forcings are critical drivers of AMV. Others have argued that changes in ocean circulation are not required. Here, we review the leading hypotheses and mechanisms for AMV and discuss the key debates. In particular, we highlight the need for a holistic understanding of AMV. This perspective is a key motivation for a major new U.K. research program: the North Atlantic Climate System Integrated Study (ACSIS), which brings together seven of the United Kingdom’s leading environmental research institutes to enable a broad spectrum approach to the challenges of AMV. ACSIS will deliver the first fully integrated assessment of recent decadal changes in the North Atlantic, will investigate the attribution of these changes to their proximal and ultimate causes, and will assess the potential to predict future changes.\nDownloads\nDownloads per month over past year", "pred_label": "__label__POS", "pred_score_pos": 0.5176608562469482}
{"content": "The Mid-Willamette Homeless Initiative began as a collaborative effort among the cities of Salem and Keizer and Marion and Polk counties. A task force and eight subcommittees worked diligently during 2016-17 on a strategic plan to identify and launch proven strategies that will reduce homelessness in the Marion-Polk county region, encompassing the cities of Keizer and Salem. Task force members included business and community leaders with expertise in social services, housing, public safety, and business.\nThe initiative’s strategic plan addressed issues in cities and counties; lack of affordable housing; best practices for reducing chronic homelessness; specialized service for veterans, seniors, victims of domestic violence, and runaway and homeless youth; and coordination of available support and education services. Contributing factors such as mental illness, addiction, lack of education and the need for transportation were also addressed. For information on the Mid-Willamette Homeless Initiative Task Force, click\nhere.\nLater in 2017, five governments – Independence, Keizer, Marion County, Monmouth, and Salem – entered into an intergovernmental agreement, formed a Steering Committee, and pooled their funds to support a staff person housed at COG that advanced the Mid-Willamette Homeless Initiative’s work. Then in 2019, the Steering Committee voted to support creating a new Continuum of Care. Staff support for the Mid-Willamette Homeless Initiative shifted its focus entirely to Continuum of Care development.\nThe five Mid-Willamette Homeless Initiative participants reached out to other governmental and nonprofit community organizations to engage in the Continuum of Care development process. The Mid-Willamette Valley Homeless Alliance was formed in September 2019 and was recognized by the U.S. Department of Housing & Urban Development as a Continuum of Care in December 2019.\nThe Mid-Willamette Valley Homeless Alliance website can be found\nhere.\nDocuments available for download:", "pred_label": "__label__POS", "pred_score_pos": 0.7132663130760193}
{"content": "When your HVAC unit is broken, your staff suffers. This leads to a decrease in productivity and an unhealthy working environment. Avoid these issues by getting a commercial HVAC repair. Cyclone Mechanical, Inc. will assess your current unit and determine what's causing the damage. This helps to maintain the condition of your system\nSchedule your commercial HVAC repair in South, FL today. Never neglect the condition of your HVAC unit\nKeeping your HVAC unit in South, FL well-maintained is key to protecting your investment. When you let us handle your commercial HVAC maintenance, you can count on us to check:\nThe physical condition of your system The state of your condensate drains If your filters are clogged or dirty\nTwice a year, we'll perform a thorough inspection to make sure your HVAC unit doesn't need to be repaired or replaced.\nIf you're in South, FL and need commercial HVAC maintenance, call now 305-506-6696\nto learn about our maintenance contracts.", "pred_label": "__label__POS", "pred_score_pos": 0.7054934501647949}
{"content": "Pressure drop across any device that presents a restriction in the flow stream should be considered when calculating the permanent pressure loss in a flow loop. This can have a significant effect with some designs, but the Enhanced Floating Rotor (EFR) design PRECISION TURBINE FLOWMETER (PFT) minimizes pressure drop due to the small areas required for the cone and rotor components of the flowmeter.\nPressure drop at recommended nominal flow rate of any size PTF utilizing the EFR design is not significant and usually in the 1 psid range. Pressure drops above the 6 psid range should be avoided due to exceeding the linear measurement range of the meter, which can impact performance and cause damage to the device.", "pred_label": "__label__POS", "pred_score_pos": 0.9994453191757202}
{"content": "Abstract\nThe last speakers of an endangered language often include many individuals who have acquired less than full productive proficiency in the language, language users Nancy Dorian (1977) called semi-speakers. When these individuals enter formal education and seek to learn or relearn their endangered heritage language, they are often frustrated by challenges to their authenticity as legitimate language users and by difficulties in effecting integration into local language networks. This study investigates the unique language-learning task faced by heritage learners of an endangered language, Scottish Gaelic, and shows how this task differs significantly from the task of learning and using a foreign language. I will argue that the results of this study have important implications for pedagogical practice and curriculum development for the teaching of endangered languages, particularly where language learning is understood, at least in part, as a strategy for language revitalization.\nKeywords ideology metaphor Scottish Gaelic authenticity identity community", "pred_label": "__label__POS", "pred_score_pos": 0.9011082649230957}
{"content": "According to the Childhood Bereavement Estimation Model, approximately 1 in 14 American children will experience a significant loss (e.g., that of a parent or sibling) during childhood. Nonetheless, it is often overlooked that children have the capacity to experience and understand the intense emotions of grief. This oversight renders children particularly vulnerable to feeling alone and helpless as they grieve. Children’s Grief Awareness Day seeks to increase awareness of the fact that children\ncan and do grieve. In the words of Dr. Alan Wolfelt, “Any child that is old enough to love is old enough to mourn.”\nOn November 19th, we strive to promote recognition of the needs of grieving children. Providing support for grieving children is critical, as research suggests that ignoring children’s grief has massive repercussions for their psychological and physical health.\nChildren and teens need to know that their perspectives are valued. This year, we want to honor the stories of individual grieving children by providing them with a platform to be heard.\nWe are collecting anonymous audio submissions from children and teens who have experienced grief.\nIf you are under 13 you cannot participate (based on federal law) without getting permission from your parent/caregiver and having your parent or caregiver submit on your behalf. 13-18 year olds\nIf you are 13-18 and have experienced the death of someone you love, recently or when you were younger, you can record an anonymous audio submission below responding to the following question:\nTo submit your audio recording, please complete the form below with your email address and age (your email address will NOT be shared or used for any other purpose than matching your age with your recording). Then click the orange button to record, enter your email again, and then you are all set! Remember, these are anonymous so please don’t share your name in your audio recording.\nChildren under 13\nWe would love to hear from children under 13, but need parent or caregiver permission to participate in this project. To submit for this project, a parent or caregiver will need to send the audio recording to us by email and sign a consent form allowing us to use it. Parents/caregivers should email us at\nsubmit@whatsyourgrief.com to request the permission form.\nAll audio files should be 90 seconds or less and should NOT include names!", "pred_label": "__label__POS", "pred_score_pos": 0.9448491930961609}
{"content": "On hot summer days, power usage in Australia skyrockets as households and businesses turn on their air conditioners. Energy usage can increase by over 45% on these days, particularly between 3pm and 6pm when both households and offices are running their air conditioning.\nThe traditional approach to these peak-demand events has been to rely on emergency power plants that operate for as little as 20 hours a year. These power stations are expensive to build and to run, and using them causes the cost of energy to increase up to 140 times during these periods. This is why energy providers like Powershop Australia are turning to a new approach: behavioural demand response.\nDemand response encourages consumers to briefly reduce their burden on the power grid during high demand periods, often using a simple prompt. This saves money for both the consumer and the power retailer, creating an incentive for both parties.\nIn a new trial, we collaborated with energy provider Powershop Australia to help reduce energy demand during these busy periods and make the most of Powershop Australia’s demand response system.\nChanging who participated in a demand response by default\nWe wanted to increase the use of Powershop Australia’s fantastic demand response program, Curb Your Power (CYP), and one strategy we used was to change the default.\nPeople who were Powershop customers, but were not in CYP, were defaulted into the program but given the option to opt out. In our trial\nthese households, who were enrolled in the demand response program by default, used 13.8% less power during peak demand events (Figure 1).\nConsumers who were already enrolled in CYP were not receptive to behaviourally informed messages. It seems that people who plan to control their energy use are already motivated, and don’t need a nudge.\nThe large impact of the default message is likely driven by two factors:\nFar more people received a message by default than by choice (99% vs 13% in the business as usual condition). Customers not already enrolled in CYP use more energy on average compared to CYP participants – this means they had more room to reduce their power usage during the event.\nThis trial highlights how effective a change in defaults can be, even when compared with other behavioural interventions. There are over 8 million households in Australia – defaulting every household into a demand response program could dramatically reduce our national energy consumption. This would remove the need for expensive power plants that sit idle for most of the year and help the environment.", "pred_label": "__label__POS", "pred_score_pos": 0.7866693735122681}
{"content": "Description\nBeginning with a blockage of the flow of the aqueous humor, this degeneration can lead to glaucoma and cataracts, where the lens becomes clouded.\nReversing this degeneration in its different stages requires a comprehensive treatment of the metabolism. When used as a long-term therapy, ADEL 17 (GLAUTARAKT) drops help effectively treat glaucoma, disturbed circulation to the eye, inflammation of the iris and cornea, sclerotic vessels and weak vision.", "pred_label": "__label__POS", "pred_score_pos": 0.6975044012069702}
{"content": "Artisanal and small-scale mining (ASM) is a vital livelihood for over 40 million people in developing countries, particularly for those living in remote, rural areas, according to the recent 2019 State of the ASM Sector report. Although it is the most important rural non-farm activity in the developing world, the sector remains under-researched. Its potential to be part of broader development initiatives, such as the United Nations’ Sustainable Development Goals (SDGs), has not been realized.\nThe World Bank’s Extractives Global Programmatic Support (EGPS) alongside partner Pact, decided to shine a light on this vital sector by creating Delve, a global platform for artisanal and small-scale mining data, with the view that complete, accurate and reliable data is a necessary precondition for any intervention in ASM – whether to formalize the sector, improve the livelihoods of poor people, or empower women working as miners. As the sole database covering artisanal and small-scale mining across the world, Delve is necessary for policymakers and practitioners to take an informed approach to the sector.\nIn April 2019, the Delve team took a crucial first step, publishing a first of its kind report on artisanal and small-scale mining.\nA first of its kind report\nThe new report explores the impact of the ‘global data gap’ on ASM and outlines how the gap can be narrowed to formalize this global sector. Drawing from online database Delve, the report identifies ways to improve data collection methodologies and presents a shortlist of ‘key data needs’ for the sector. The report features in-depth analysis of the data gaps and importance of ASM through regional and country case studies, including Ghana, Guyana, India, Mongolia, Morocco and Peru.\nRegional findings include:\nSub-Saharan Africa is home to one of the largest numbers of artisanal and small-scale miners in the world, close to an estimated 10 million, with at least a further 60 million reliant on the sector. In Latin America and the Caribbean, more than 2 million people directly engage in ASM – up from an estimated 650,000 artisanal and small scale miners in 1999, but region-wide moves to collect complementary social and economic information about the sector have been disappointing. ASM is a key livelihood strategy for the poor in East Asia and Pacific, with robust data focused on small-scale gold mining ASM in South Asia remains in the shadows – though we know it is driven by poverty and heavily tied to subsistence agriculture. Data is urgently needed across South Asia given the region’s widespread poverty – particularly a better understanding of the role the sector plays in alleviating hardship and supporting rural families “Bridging the data gap is the first step in removing the veil of invisibility from the millions of men and women miners who are integral to our global economy,” said Karen Hayes, Vice President of Pact’s Mines to Markets initiative.", "pred_label": "__label__POS", "pred_score_pos": 0.5404518246650696}
{"content": "Q: If a 17-year vested federal law enforcement officer has his TS security clearance revoked and in turn is terminated, does he still get his retirement at 62? A: In most circumstances, yes. Termination from federal employment does not affect an employee’s annuity or retirement pay. However, a federal employee loses his or her annuity if he or she is convicted of certain crimes codified in 5 U.S.C. § 8312. These crimes are narrowly tailored, concerning acts of disloyalty to the United States. For example, 5 U.S.C. § 8312 lists the crimes of treason, sabotage, espionage, and insurrection. This…\nBrowsing: Michael J Sgarlat\nQ: I would like to know if there is an allowed discrepancy of GS levels for the same position within the DOD. If not, what are potential methods of remedy that I should explore? A: A grade level represents a band or range of difficulty. The U.S. Office of Personnel Management (“OPM”) prepares classification standards and functional guides, which are used when classifying a grade of a position. If the work assigned to a position is covered by criteria in a standard for a specific occupational series, the work is evaluated by that standard. However, if there are no specific…\nQ: If I resign, would I have no recourse with MSPB? A: Generally not. An employee-initiated action, like resignation, is presumed voluntary and outside of the Merit System Protection Board’s (MSPB) jurisdiction. Freeborn v. Dep’t of Justice, 119 M.S.P.R. 290, 294 (2013). However, if the federal employee presents sufficient evidence to establish that the action was obtained through duress, coercion, or shows a reasonable person would have been misled by the agency, the presumption of voluntariness is removed. Green v. Dep’t of Veterans Affairs, 112 M.S.P.R. 59, 63 (2009). The employee has the burden of proving the MSPB’s jurisdiction by…", "pred_label": "__label__POS", "pred_score_pos": 0.7437934875488281}
{"content": "Inadequate Brain Glycogen Or Sleep Increases Spreading Depression Susceptibility Date2018 Author\nKılıç, Kıvılcım\nKarataş, Hülya\nDönmez Demir, Buket\nEren Koçak, Emine\nGürsoy Özdemir, Yasemin\nCan, Alp\nPetit, Jean-Marie\nMagistretti, Pierre J.\nDalkara, Turgay\nxmlui.mirage2.itemSummaryView.MetaDataShow full item record Abstract\nObjective: Glycogen in astrocyte processes contributes to maintenance of low extracellular glutamate and K+ concentrations around excitatory synapses. Sleep deprivation (SD), a common migraine trigger, induces transcriptional changes in astrocytes, reducing glycogen breakdown. We hypothesize that when glycogen utilization cannot match synaptic energy demand, extracellular K+ can rise to levels that activate neuronal pannexin-1 channels and downstream inflammatory pathway, which might be one of the mechanisms initiating migraine headaches. Methods: We suppressed glycogen breakdown by inhibiting glycogen phosphorylation with 1,4-dideoxy-1,4-imino-D-arabinitol (DAB) and by SD. Results: DAB caused neuronal pannexin-1 large pore opening and activation of the downstream inflammatory pathway as shown by procaspase-1 cleavage and HMGB1 release from neurons. Six-hour SD induced pannexin-1 mRNA. DAB and SD also lowered the cortical spreading depression (CSD) induction threshold, which was reversed by glucose or lactate supplement, suggesting that glycogen-derived energy substrates are needed to prevent CSD generation. Supporting this, knocking down the neuronal lactate transporter MCT2 with an antisense oligonucleotide or inhibiting glucose transport from vessels to astrocytes with intracerebroventricularly delivered phloretin reduced the CSD threshold. In vivo recordings with a K+-sensitive/selective fluoroprobe, Asante Potassium Green-4, revealed that DAB treatment or SD caused a significant rise in extracellular K+ during whisker stimulation, illustrating the critical role of glycogen in extracellular K+ clearance. Interpretation: Synaptic metabolic stress caused by insufficient glycogen-derived energy substrate supply can activate neuronal pannexin-1 channels as well as lower the CSD threshold. Therefore, conditions that limit energy supply to synapses (eg, SD) may predispose to migraine attacks, as suggested by genetic studies associating glucose or lactate transporter deficiency with migraine.", "pred_label": "__label__POS", "pred_score_pos": 0.7340880632400513}
{"content": "Much attention has been focused on the reaction of the magnetosphere to the solar wind during the recent extended solar minimum (2006–2010). Although this period was exceptionally quiet when categorized by some parameters (e.g., the number of sunspots) the solar wind still contained features which impacted the Earth's magnetosphere and caused geomagnetic disturbances. Recurrent corotating interaction regions (CIRs) and associated high-speed solar wind streams (HSSs) are typically associated with the declining phase of the solar cycle and were a regular feature of the solar wind during the most recent solar minimum. Here we compare and contrast strong and weak HSSs in the solar wind and their subsequent effect within the Earth's magnetosphere. We find significant differences between strong and weak HSS effects in the plasmasphere, in the ion and electron plasma sheets, and in the outer electron radiation belt. A density-temperature description of the outer radiation belt is shown to shed light on why the radiation belt flux is observed to return at a higher level after the arrival of strong HSSs than before strong HSSs and why the flux is observed to return at a lower level after the arrival of weak HSSs than before weak HSSs.", "pred_label": "__label__POS", "pred_score_pos": 0.7604554295539856}
{"content": "Over recent years, many South Africans have lost money after being taken in by advanced fee scams. An advanced fee scam is a hoax where you are promised access to a large sum of money as long as you pay a deposit first. Someone may trick you into paying an advanced fee to access a loan, an inheritance, an investment opportunity or money you are told you have won in a competition. Criminals may also ask you for help with transferring a large amount of money out of the country.\nHow common are advanced fee scams?\nOver a five-year period, more than 5000 advanced fee scams were reported to the South African Reserve Bank. 22% of South Africans using e-banking services were taken in by scams in one year. Almost a third of these were advanced fee or 419 scams. A 419 scam is a type of advanced fee scam. In a 419 scam, someone is encouraged to send money to a stranger in exchange for a larger sum that never materialises.\nCommon scamming techniques\nIf you are asked to pay a fee to access money or some financial services, you may be being scammed. Once a scammer receives your payment, chances are you will never hear from them again – unless they ask for more cash. Scammers use a range of channels to seek out their victims. These include email, text, phone calls, WhatsApp and social media.\nFake loans, competitions and emails\nScammers may attempt to dupe you by promising you a large loan with no credit checks or an incredibly low interest rate. They may tell you that you’ve won a competition that you don’t remember entering or may inform you that someone you don’t know has left you an inheritance. Some scammers pretend to represent well-known companies. Famous lender Wonga’s brand image was used without permission by criminals several years ago as the front for an email and sms scheme of authentic-looking messages that look just like genuine correspondence. However, when you check the email address it may look strange or bogus.\nEmails can seem very authentic\nAnother tell-tale sign is when a scammer refers to you as ‘sir’ or ‘madam’ rather than your name. However, some scammers will address you by your name. The correspondence you receive may also have spelling and grammatical errors, though this isn’t always the case. Some correspondence can seem very authentic indeed, which is why so many people fall for it.\nWhat you need to do\nIt’s vital to ignore any correspondence you receive if you do suspect someone is trying to scam you. Don’t even respond to say you believe the message is bogus – inform the police immediately instead. If you do believe someone has targeted you with an advanced fee scam, contact the police by sending a message to [email protected]\nScamming during the pandemic\nCriminals have been targeting unsuspecting members of the public via a number of methods during the global pandemic. In 2020, British banks revealed some of the most common techniques being used by criminals recently. Scammers have recently been sending out fake government emails offering Covid-19 support grants. However, links inside the emails may steal your personal and financial information. Emails offering Covid-19 relief fund access have also been circulating. Authentic-looking emails offering reductions in household bills have also been in circulation. Again, these are designed to obtain your personal and financial information.\nNew scams emerging\nMany people have received fake emails telling them they have been in contact with someone who has contracted the virus. Once someone clicks a link inside the email, they may be taken to a fake website and asked for personal information. The website may also infect your computer, tablet or phone with malware. Fake adverts for products like hand sanitizer and face masks have also been found online. Once the victim sends their payment for these items, they don’t receive anything at all.\nIt’s essential to stay on top of the latest online scams to avoid being parted with your money. New scams are being launched all the time, so remain as vigilant as you possibly can.", "pred_label": "__label__POS", "pred_score_pos": 0.5688766241073608}
{"content": "posted on\nJan 18, 2018 by David McIntire\nTo date, many digital transformation initiatives have been primarily focused on customer-facing technologies. Changing customer preferences and the rise of new digitally native competitors have driven incumbent firms to see customer experience as a source of competitive advantage or as table stakes to maintain relevance. In NelsonHall’s recent survey of IT service buyers across 18 sectors, 61% identified both improved customer experience and increasing average revenues per customer as highly important business priorities.\nThese business priorities are primarily being addressed through digital initiatives, and 73% of buyers identified improving customer experience and customer service as a highly important benefit of digital.\nBut companies are also increasingly looking beyond the customer experience for digital initiatives. It should be no surprise that other business priorities identified as highly important by a significant portion of IT services buyers include increasing rate of automation (72%) and digitalizing their operations (67%).\nThese initiatives are increasingly looking at digital as an end-to-end operational transformation which enables the realization of other key benefits, including reducing operating costs and improving service fulfillment and turnaround time (each highly important to 73% of buyers).\nWhile this has always been a focus area for sectors such as manufacturing and energy, it is also being prioritized increasingly in consumer-facing sectors. Companies are recognizing that the customer experience goes beyond the digital channel and spans the entire customer lifecycle, hence the importance placed on service fulfillment. Objectives being sought by consumer-facing sectors reflect this focus, expanding beyond customer experience to end-to-end digital transformation. Specific objectives cited by consumer-facing sectors include:\nIncreasing rate of automation in operations. This is being prioritized by more than 70% of organizations across retail, healthcare provider, travel & transport, retail & commercial banks, and media\nDigitalizing operations, cited by ~78% of organizations across travel & transport, retail & commercial banks and media\nReducing service turn-around time, cited by 53% of organizations across healthcare provider, media, travel & transport, retail & commercial banking, and retail.\nTo achieve these defined objectives, consumer-facing organizations are targeting digital initiatives in non-customer-facing functions. Specific industries that have highlighted digitalization of end-to-end functions as a priority include:\nTravel & transport: transforming supply chain and improving real-time asset tracking are the two most commonly identified digital initiatives by travel and transport companies. IoT/sensor-based applications is the most commonly cited digital technology and acts as the primary avenue for addressing these initiatives, a high priority area for nearly one in three organizations\nHealthcare providers: while primary focus has been on patient care, including patient self-service, the second highest priority area is revenue cycle management, the end-to-end process from scheduling to payment, highlighted by 55% of organizations as being pursued currently. This primary internal focus is on the financial processes that support the end of the payment cycle\nCPG: with 64% placing priority on the order management function, CPG companies, which sit at the intersection of manufacturing and consumers, are looking at optimizing the supply chain through broader integration and cloud-based applications. CPG companies also identified IoT/sensor-based applications as the most commonly implemented digital technology, with a primary focus on using IoT in manufacturing, procurement/supply chain, and warehouse management\nRetail: improving and expanding integration across the supply chain is a key focus area for retail. Implementing IoT/sensor-based applications is the most common avenue for addressing this, a high priority for more than 40% of retail companies. IoT/sensor-based applications initiatives are primarily focused on addressing these supply chain improvements through improving warehouse management and logistics.\nConsumer-facing industries have been undergoing significant digital disruption and are looking to transform interactions with their customers. While that continues, companies are increasingly focusing on how operations beyond the customer interface impact the customer experience. In 2018, this focus on improving end-to-end operations to improve customer service will continue apace.", "pred_label": "__label__POS", "pred_score_pos": 0.8464925289154053}
{"content": "The public health crisis has required advocates to adapt to many changes. This webinar showcases the successes and challenges of providing client-centered and trauma-informed services in the criminal justice system. The presenters further explore how practitioners have adapted the way they engage with victims/survivors, their CCR, and each other and how our ongoing partnerships in these systems have enabled professionals to continue to provide services for survivors.\nSearch for similar resources", "pred_label": "__label__POS", "pred_score_pos": 0.9967172145843506}
{"content": "Don’t miss this relevant and practical offering with Sue Wehrspann on December 3rd!\nCritical challenges are unrelenting during this global pandemic. Navigating change, organizational uncertainty, remote work, and pandemic fatigue can be stressful and difficult. Adjusting to these challenges is not easy, especially with the future unknown. These disruptions in routine often cause decreased productivity as a new balance is sought. It can be overwhelming. This session offers immediate solutions to real situations. Utilizing the latest neuroscience techniques, identify effective solutions for these unprecedented times.\nRegister here!\nJoin us this month for Emotional Intelligence Skills, Workplace Civility, Employment Law: Issue Spotting, Mitigating Unconscious Bias, Communication Tools: Interpersonal Mastery and more! Check out our 2021 January-June catalog! Get the best in leadership development, supervisory skills, legal and other timely topics. In addition, please peruse our coaching, mediation and investigation services Coming next week- Supervising a Virtual Workforce, Mitigating Unconscious Bias, Employment Law: Issue Spotting, Documentation Skills and Harassment Prevention. If what you need is not listed, please reach out to book a custom session at your location! lm@em-lm.com Join Jenny Douras for this informative, practical and relevant session!\nSupervising can already be tough, but this shift to virtual environments can make the role even harder, particularly if it is new to you and your team. Learn how to effectively lead, motivate, guide, and engage your team in this new remote role. Set strategies for building and maintaining connection, fostering a culture of trust, and how to avoid mistakes that might be amplified in virtual settings. Identify best practices for you and your team as you continue to navigate this next normal for how work gets done.\nDon’t miss Time Management with Doug Gertner, Resilience with Lisa Barbeau and Listening Skills with Kimberly Searfoorce! If you are looking for a companion offering to Nativagting Pandemic Fatigue, please join me for Resilience: Finding Happiness in Hard Times on November 11th! This session is designed for teams and individuals looking to build capacity in navigating this ongoing crisis.\nDon’t miss this session with master facilitator Doug Gertner on Time Management and the art of mastering multiple priorities.\nThis seminar provides best practices and skills that emphasize priorities, organization, and staying on task. Learn to identify and attain long-term professional and personal goals. Discover the time wasters which are consuming your day and how they affect your performance. Better manage interruptions and the deluge of e-mails, voicemails, and other communications. Redesign your day so you can restore balance in your life and leave with the tools to make time for what is most important.\nOct 14, Nov 11 8:30-4:00 $245 Facilitator: Doug Gertner, Ph.D., Workplace Seminars & Solutions Don’t miss our virtual open enrollment offerings of Customer Relations, Lean Processes: Mindset & Tools, Creating a Kinder Workplace, Navigating Pandemic Fatigue. and Presentation Skills. No membership needed!\n#organizationaleffectiveness; #kindness, #resilience", "pred_label": "__label__POS", "pred_score_pos": 0.7452776432037354}
{"content": "Trade Reform and the Evolution of Agglomeration in Vietnamese Manufacturing\nIt is well-documented that agglomeration contributes to productivity growth. However, concentrations of workers could also lead to increasing regional income disparities. Therefore, understanding the evolution of agglomeration is relevant for the formulation of industrial policy and inclusive growth. This study documents the extent, pattern, and determinants of agglomeration in Vietnamese manufacturing during 2002–2016, a period when substantial economic reform took place. Our major findings are three-fold. First, agglomeration, as measured by the Ellison–Glaeser index, has declined since the mid-2000s. Second, there exists significant sectoral heterogeneity in the level and trend of agglomeration. Third, we do not find a significant impact of trade and foreign direct investment on agglomeration per se. However, foreign direct investment in port districts does contribute to disagglomeration.", "pred_label": "__label__POS", "pred_score_pos": 1.0000064373016357}
{"content": "On August 17, 2019, the United Kingdom’s\nDepartment for Environment, Food, and Rural Affairs (DEFRA) published a press release announcing a public consultation to help develop the country’s National Food Strategy. The UK announced that it is planning “for a radical shake-up of the UK’s food industry” and has launched “a call for evidence, giving everyone from consumers, farmers and food producers, to scientists and academics, an opportunity to shape how we produce, sell and consume food in the UK.” The feedback received will be used “to ensure the food industry is fit for the future, supports growth, enhances the environment and is resilient to the challenges posed by climate change.” Specifically, the strategy will review and build on existing agricultural, fishery, industry, childhood obesity, and environment bills.\nIn a note to academic scientists,\nDEFRA highlighted that additional technical evidence will be asked for later in the consultation process. However, any new research that “strengthens or challenges the conclusions of previous reviews into specific topics” is welcome now, including not yet published information that could “contribute significantly to the debate.” The consultation is open online until October 25, 2019. Read more\nDEFRA (August 17, 2019). “Public to have their say on the food system of the future.”\nDEFRA (August 17, 2019). “National Food Strategy – Call for Evidence.”", "pred_label": "__label__POS", "pred_score_pos": 0.5056557655334473}
{"content": "The University of California, San Diego, commonly abbreviated as UCSD, is a public higher education institution, placed in the heart of the community of La Jolla, San Diego, United States. It was established in 1960 with donations from the city and the American aerospace corporation General Dynamics.\nThe institution is part of the state-wide University of California system, alongside other 9 semi-autonomous public institutions. UCSD is among the US Public Ivy colleges, whose objective is to provide students with the same quality of education as can be found in Ivy League’s private colleges.\nAs an important contributor in research activities, the university comprises of 6 undergraduate schools. It also features 3 graduate colleges, 2 medical centers and the famous Scripps Institution of Oceanography, which is the largest geological and marine science institute in the world.\nA notable feature of the university is its numerous research institutes which receive considerable public funding. This investment has led to nearly 30,000 newly created jobs, notable profits generated from the sale of licensed technology and the launch of over 600 new companies operated by UCSD affiliates.\nTo maximize the level of collaboration and stimulate discussion, students and faculty members inhabit the same residential areas, part of the main university campus which is built over a 1500 acre plot of land. Students can also enjoy visiting some of UCSD’s recreational facilities, which include a eucalyptus forest, aquarium, and museum.\nStudent life at UCSD can be exciting for music lovers, who can attend November’s Hallabaloo music festival, which has featured acts such as Macklemore and Snoop Dogg in the past. Sports enthusiasts have the opportunity to support or even join some of the 23 competitive teams representing the university, in sports such as rugby, ice hockey and tennis.\nUCSD has a network of more than 170,000 graduates and faculty members, including over 15 Nobel Laureates.", "pred_label": "__label__POS", "pred_score_pos": 0.7306621074676514}
{"content": "Comprehensive secure remote access solutions to adapt to new ways of working and minimize risk\nThe adoption of emerging technologies has become a differentiator, granting firms the competitive edge, particularly during the COVID-19 pandemic. The pandemic has impacted every aspect of the daily workflow for employees in Capital Markets firms. Trading desks are not the same. The work-from-home culture has accelerated the digital transformation across all functions in investment banks and buy-side firms. However, it has also left business units befuddled about the use of technologies. This change in the way of working brings new considerations and some inherent risks. The most obvious risk is cyber security—a poorly designed API can provide a window of opportunity for cybercriminals. Wipro secure remote access solutions perform quick assessments of infrastructure, requirements and expected maturity, while validating user / device posture to allow or deny, or restrict in the context of accessing applications or resources. This solution provides secure VPN access, software defined perimeter (SDP) services, secure VDI access, where these are used independently or in combinations to cater to customer specific needs.", "pred_label": "__label__POS", "pred_score_pos": 0.9032019376754761}
{"content": "Patriot Paws trains service dogs to provide comfort and care to veterans who have been wounded both physically and mentally. Each year, many vets come home from their tours of duty with both physical and emotional injuries. To help them become independent once again, Patriot Paws trains service dogs to help veterans readjust to everyday life. Founded less than 10 years ago, they have more than 30 dogs graduate from their two-year training program each year, and they are expanding quickly. Any veteran with a service-related disability may apply for a dog, and all dogs are given free of charge. After a veteran’s application for a dog is accepted, they are matched with a puppy even before the dog’s training begins.\nOnce a veteran receives his service dog, the veteran’s life changes forever. These dogs are life-long companions who accompany the veteran everywhere he go. Naturally intelligent and carefully trained, these dogs can perform tasks as “simple” as opening doors or as complex as bringing their owners a phone during an emergency. Beyond assisting their owners with daily chores, these dogs are trained to mitigate the symptoms of PTSD. Years of training combined with a high natural intelligence create a partner that provides the support, comfort, and protection our disabled veterans need.", "pred_label": "__label__POS", "pred_score_pos": 0.6945178508758545}
{"content": "NCASE Resource Library Featured Resources\nThis publication features some of the best resources, including webinars, briefs, and toolkits, available in the online NCASE Resource Library, developed for both practitioners and system builders.\nThese selected resources, curated by NCASE, offer ideas and information for OST system leaders to support recovery from COVID-19.\nThe NCASE Out-of-School Time Professional Development System-Building Toolkit was designed to assist states as they build professional development systems inclusive of school-age providers.\nSearch for Resources ? Search Results Filter By Reset Selections Expand All Filters Topics Resource type Publisher Search Results Filter By\nThis brief, based on a longer white paper, identifies and summarizes key findings in the existing literature on 12 protective and promotive factors relevant to afterschool.\nThis brief explores how programs that use a positive youth development approach can embed a racial equity perspective to effectively meet needs of youth of color. It suggests that programs think about who is offered program services, build staff capacity to recognize personal bias and structural inequalities, and insure leadership opportunities.\nThis issue brief provides recommendations for how to best support home-based child care providers during COVID-19, recognizing that this is an especially important part of the supply right now, and was already seeing instability and a decline in providers.\nThis PowerPoint presentation explores key principles for effective business management. It describes the concept of shared services. Some slides demonstrate the extensive resources of the ECE Shared Resources tool used by more than 20 states. It provides examples of strengthening business practices in New Hampshire and Pennsylvania.\nThis issue brief explores best practices for afterschool staff supervision of youth to ensure safety. It outlines the legal definition of neglect. It includes strategies for risk management including facility inspection, proper equipment, activity planning, first aid, and emergency preparedness.", "pred_label": "__label__POS", "pred_score_pos": 0.7742760181427002}
{"content": "Abstract\nObjective: The Keep It Off trial evaluated the efficacy of a phone-based weight loss maintenance intervention among adults who had recently lost weight in Minnesota (2007-2010). Methods: 419 adults who had recently lost ≥ 10% of their body weight were randomized to the \"Guided\" or \"Self-Directed\" intervention. Guided participants received a 10 session workbook, 10 biweekly, eight monthly and six bimonthly phone coaching calls, bimonthly weight graphs and tailored letters based on self-reported weights. Self-Directed participants received the workbook and two calls. Primary outcomes are weight change and maintenance (regain of < 2.5% of baseline body weight). Results: Mixed model repeated-measures analysis examining weight change revealed a significant time by treatment group interaction (p < 0.0085). Guided participants regained significantly less weight than the Self-Directed participants at 12 and 24. months. The odds of 24. month maintenance were 1.37 (95% CI: 0.97-2.03) times greater in the Guided than in the Self-Directed group. When maintenance rates were compared across all follow-ups, there was a consistently higher maintenance rate for Guided participants (HR 1.31, 95% CI: 1.12-1.54). Conclusions: A sustained, supportive phone- and mail-based intervention promotes weight loss maintenance relative to a brief intervention for participants who have recently lost weight.\nKeywords Behavioral intervention Maintenance Obesity Weight loss", "pred_label": "__label__POS", "pred_score_pos": 0.9735593795776367}
{"content": "Abstract\nPurpose: Whether dyspnea, chest wall dynamic hyperinflation, and abnormalities of rib cage motion are interrelated phenomena has not been systematically evaluated in patients with chronic obstructive pulmonary disease (COPD). Our hypothesis that they are not interrelated was based on the following observations: (i) externally imposed expiratory flow limitation is associated with no rib cage distortion during strenuous incremental exercise, with indexes of hyperinflation not being correlated with dyspnea, and (ii) end-expiratory chest wall volume may either increase or decrease during exercise in patients with COPD, with those who hyperinflate being as breathless as those who do not. Methods: Sixteen patients breathed either room air or 50% supplemental O2 at 75% of peak exercise in randomized order. We evaluated the volume of chest wall (Vcw) and its compartments: the upper rib cage (Vrcp), lower rib cage (Vrca), and abdomen (Vab) using optoelectronic plethysmography; rib cage distortion was assessed by measuring the phase angle shift between Vrcp and Vrca. Results: Ten patients increased end-expiratory Vcw (Vcw,ee) on air. In seven hyperinflators and three non-hyperinflators, the lower rib cage paradoxed inward during inspiration with a phase angle of 63.4° ± 30.7° compared with a normal phase angle of 16.1° ± 2.3° recorded in patients without rib cage distortion. Dyspnea (by Borg scale) averaged 8.2 and 9 at the end of exercise on air in patients with and without rib cage distortion, respectively. At iso-time during exercise with oxygen, decreased dyspnea was associated with a decrease in ventilation regardless of whether patients distorted the rib cage, dynamically hyperinflated, or deflated the chest wall. Conclusions: Dyspnea, chest wall dynamic hyperinflation, and rib cage distortion are not interrelated phenomena.\nKeywords Chest wall kinematics dynamic hyperinflation ergometry optoelectronic plethysmography oxygen supplementation ASJC Scopus subject areas Orthopedics and Sports Medicine Physical Therapy, Sports Therapy and Rehabilitation", "pred_label": "__label__POS", "pred_score_pos": 0.658888578414917}
{"content": "Masdar’s Chief Financial Officer, Niall Hannigan, joined more than 1,000 global thought leaders, government officials and business leaders at the recent Milken Institute’s 2020 Middle East and Africa Summit in Abu Dhabi.\nThe two-day event, held from February 11-12, featured a range of speakers including Mariam Almheiri, UAE Minister of State for Food Security, Khaldoon al Mubarak, Chief Executive Officer of Mubadala Investment Company, Paul Ryan, a former US House of Representatives Speaker and Deepak Chopra, the Chief Executive Officer of the Chopra Institute. Hannigan joined a high-level panel at the summit, where participants discussed the significant growth of renewable energy in the Middle East, particularly in the UAE. During the panel, titled The New Energy Order: A Shift Toward Renewables, Hannigan said: “When Masdar was launched in 2006, renewables was a nascent industry and sustainability was nowhere near the top of the agenda. This has changed. Thankfully, the world is now taking climate change mitigation more seriously, and renewables is now part of the mainstream with an undeniable place in the energy mix offering cost competitive solutions when compared with conventional sources.", "pred_label": "__label__POS", "pred_score_pos": 0.9832538366317749}
{"content": "Medication errors in the hospital have been studied, quantified, and systematically evaluated for potential solutions. A notable exception is the perioperative setting, where medications given by anesthesiologists often bypass standard safety checks. This study is the largest prospective observational study of anesthesia-related medication events available to date. At least one medication error or adverse drug event occurred in nearly half of the 277 operations observed. Approximately 1 in 20 perioperative medication administrations resulted in a medication error or adverse drug event; 80% of these errors were deemed preventable. None of the errors resulted in death, but 2% were considered life-threatening. There were no differences in event rates among resident physicians, nurse anesthetists, and staff anesthesiologists. The study took place at an academic hospital with substantial local expertise in medication safety, where operating rooms already used a barcode-assisted syringe labeling system. An accompanying editorial suggests that medication error rates may therefore be even higher in other settings and community hospitals.", "pred_label": "__label__POS", "pred_score_pos": 0.9968900084495544}
{"content": "Aim: To measure epidermal growth factor receptor (HER1/EGFR) expression in a range of soft tissue sarcoma (STS) patient samples. Method: HER1/EGFR expression was examined by immunohistochemistry in archival tissues of 46 STS patients. Results: HER1/EGFR was positively expressed in 36/46 of STS samples distributed among different histological types. The levels of HER1/EGFR in STS tumour tissues in positive samples were higher compared to those in nearby normal tissues. Conclusion: HER1/EGFR is significantly expressed in soft tissue sarcomas, which is a finding reflected in other series. The significance of this finding for targeted therapy is as yet unknown.", "pred_label": "__label__POS", "pred_score_pos": 0.9813498854637146}
{"content": "Published on in Vaccine Update for Healthcare Providers\nOn Nov. 9, 2020, the pharmaceutical company, Pfizer, in collaboration with BioNTech SE, a German company, sent out a press release describing an interim analysis of their SARS-CoV-2 mRNA vaccine. Of the 43,538 participants enrolled in the trial, which were divided equally (1:1) in the vaccine and placebo groups, 38,955 had completed a second dose. After evaluating the first 94 illnesses in the trial, researchers found that the mRNA vaccine was 90% effective at preventing mild to moderate infection. This meant that roughly 86 people with COVID-19 were in the placebo group and eight were in the vaccine group. These observations were made at least seven days following the second dose, which meant that the vaccine was effective within 28 days of the first dose.\nPfizer pointed out that 30% of U.S. participants had racially and ethnically diverse backgrounds, but didn’t state the percent of participants that were greater than 65 years of age. The study plans to evaluate the effectiveness of the mRNA vaccine in preventing severe disease as well as effectiveness in those who had already been exposed to the virus.\nPfizer stated that it could now produce up to 50 million doses in 2020 and 1.3 billion doses in 2021.\nNext Steps\nMaterials in this section are updated as new information and vaccines become available. The Vaccine Education Center staff regularly reviews materials for accuracy.\nYou should not consider the information in this site to be specific, professional medical advice for your personal health or for your family's personal health. You should not use it to replace any relationship with a physician or other qualified healthcare professional. For medical concerns, including decisions about vaccinations, medications and other treatments, you should always consult your physician or, in serious cases, seek immediate assistance from emergency personnel.", "pred_label": "__label__POS", "pred_score_pos": 0.6343865394592285}
{"content": "Attend a session and schedule a meeting with James Pender, Lafayette Federal’s CFS 1 Financial Advisor, to receive a $25 LFCU Mastercard® Gift Card!2\nWithin just a few months, the COVID-19 pandemic has impacted not only our health, but also our finances, bringing uncertainty particularly for our retirement and investment accounts.\nThe increased volatility of the stock market, low interest rates, and stressed economy leave us financially vulnerable. This is true for many individuals investing for upcoming life events, and those who have experienced significant reductions in their savings.\nJoin James Pender, Lafayette Federal’s CFS Financial Advisor, for this webinar, where he will discuss the current environment and factors to consider for your financial plan.\nMore than ever, solid financial planning is essential in meeting your retirement goals.\nOur members have access to Co-Op Network Shared Branches & ATMs for all basic transaction needs.\nAccess branches and ATMs nationwide\nVisit one of our eight branch locations, conveniently located in DC, Maryland and Virginia.\nSchedule a branch visit today\nDreaming of a new ride? Let us finance your next new, used, or fuel-efficient vehicle.\nRates as low as 2.375% APR*", "pred_label": "__label__POS", "pred_score_pos": 0.8285636901855469}
{"content": "Research output: Contribution to journal › Article\nOpen\nWe report a genome-wide association scan in over 6,000 Latin Americans for features of scalp hair (shape, colour, greying, balding) and facial hair (beard thickness, monobrow, eyebrow thickness). We found 18 signals of association reaching genome-wide significance (P values 5 × 10(-8) to 3 × 10(-119)), including 10 novel associations. These include novel loci for scalp hair shape and balding, and the first reported loci for hair greying, monobrow, eyebrow and beard thickness. A newly identified locus influencing hair shape includes a Q30R substitution in the Protease Serine S1 family member 53 (PRSS53). We demonstrate that this enzyme is highly expressed in the hair follicle, especially the inner root sheath, and that the Q30R substitution affects enzyme processing and secretion. The genome regions associated with hair features are enriched for signals of selection, consistent with proposals regarding the evolution of human hair.\nID: 24375465", "pred_label": "__label__POS", "pred_score_pos": 0.9640209078788757}
{"content": "Despite being only the third-largest producer of wine, Spanish wines are some of the world's most popular. The country's varied climates also meant a wide range of wines, and these spirits reflect the unique cuisine and culture of each wine region. Spanish winemakers are also dedicated to their traditions, ensuring that every bottle remains consistent.\nAnother contributing factor to the popularity of Spanish wines is accessibility. As many Spanish wineries will pre-age their wines in oak barrels or bottles before selling them, consumers—especially first-timers—can sample the wines without the expensive storage investment. Spanish wines are also more moderately priced compared to their French and Italian counterparts.\nTwo key features of wine from Spain are the Denominación de Origen or Destination of Origin (DO), and aging. The DO tells consumers the geographical identity, or where the wine is made—from the type of grapes to how vines are maintained or harvested. This is usually shown on the bottle's label or cork.\nMeanwhile, labels such as \"Joven,\" \"Crianza,\" \"Reserva,\" or \"Gran Reserva\" indicate how long the Riejo region wines are aged. The meanings of these labels will depend on whether the wine is red or white and correspond to different levels of aging.\nFor a more in-depth look at Spanish wines, as well as a list of highly recommended red and white wines, continue to the infographic below.\nInfographic Source:https://www.txanton.com.ph/post/spanish-wines-illustrated-guide", "pred_label": "__label__POS", "pred_score_pos": 0.8753697276115417}
{"content": "I've been practicing yoga \"seriously\" for almost two and a half years. I began yoga mostly because I needed to start exercising again after an intense job kept me from working out. I felt remarkably lazy. I thought, mistakenly, that yoga would be easy and I was hopeful that it would be bizarre enough to distract me from feeling as miserable as working out can often make you feel.\nI was quite wrong and I'm so grateful for that.\nYoga has done some wonderful things for my body (the usual suspects of increased flexibility, strength, balance etc.) and wonderful things for my general approach to exercise. But, yoga definitely is not easy, and it's often unpleasant. I love that yoga continues to challenge and frustrate me while also being a necessary part of my sanity and well-being. I crave it,...", "pred_label": "__label__POS", "pred_score_pos": 0.7152047753334045}
{"content": "If you like cooking and working in the kitchen, you would be aware of the excitement that comes with using a newly bought kitchen appliance. In fact, the market is now flooded with several kinds of unique appliances you can make use of. These are also available in very cheap prices. We all have those toasters, mixers and sandwich makers in our kitchens. However, there are several unique kitchen supplies that you may not even know exist! Here are some of these convenient and unique appliances you must buy for your kitchen.\nFrozen drink maker – A frozen drink is wonderful in the summer. However, nobody fancies making it. This is because the process involves crushing ice while separately making a drink. It involves mixing the two while making sure that the ice does not melt. You can now avoid this hassle by buying a frozen drink maker. It automatically shaves ice and mixes it with your drink to create the perfect concoction.\nYogurt maker – We all have, at one time or another, made yogurt at home. This is because it is not only cheap but also fresh compared to packed yogurt. However, it can often go wrong. This is why you should now buy a yogurt maker! Did you know such a kitchen appliance even existed? This is somewhat like a mixer that cooks milk until it reaches a thick consistency. You can control the cooking process and can turn the machine off when the yogurt has reached the thickness you prefer.\nDrink chiller – It can often be frustrating when you want a cold drink but have to wait for it to chill in the freezer. Often, people simply resort to going over to the store to buy a chilled drink. However, with a beverage chiller in your kitchen, you do not have to do this. This is a kitchen appliance that spins a can of drink in ice and water. You can set a certain temperature and the machine will stop spinning when it reaches the specified temperature!\nSome people might think that such kitchen supplies are a waste of money. However, if you think about it, you will realize that you almost always have to stop at the store to buy something that you cannot make at home. You can avoid such expenses by investing in some useful and unique kitchen supplies.", "pred_label": "__label__POS", "pred_score_pos": 0.9666877388954163}
{"content": "Beverage Manufacturers Exploring Ready-To-Drink Category In India Amid COVID-19\nMonday, June 29th, 2020 | 677 Views\nAmidst the COVID-19 pandemic, the beverage industry has witnessed a significant shift in the purchasing preferences of consumers in India, with steady rise and strong inclination towards ready-to-drink (RTD) beverages. This shift has encouraged the beverage manufacturers to re-evaluate their innovation strategies and explore options to diversify their portfolios, says GlobalData.\nAccording to GlobalData COVID-19 survey, almost 40 percent Indian consumers bought more quantity of juices and squashes than before while 37 percent bought more dairy beverages. The survey also reveals that 60 percent of consumers prefer packaged drinks compared to freshly prepared alternatives. This implies that even though packaged RTD beverage concept is not new, the restrictions on movement due to nationwide lockdown has encouraged the consumers to stockpile RTD beverages.\n“India has increasingly been looked upon as a promising market for the RTD beverage category over the past few years as the consumption continues to rise across the country. Panic buying and stockpiling during COVID-19 has put RTD beverages in demand more than ever and forced beverage brands to consider alternative ways to align with the consumers’ priorities,” said Shagun Sachdeva, Consumer insights analyst at GlobalData.\nLeading Indian beverages manufacturers such as Nestlé, PepsiCo and Coca-Cola are forecast to be the worst hit due to the pandemic. All these players registered significant volume drops due to the shutdowns of malls, restaurants and cinemas amid the lockdown. In April 2020, Coca-Cola reported a five percent decline in unit case volume in bottling operations in India, due to the lockdown enforced from 23 March 2020. Therefore, companies have been under pressure to undertake measures for streamlining production and mitigate risk of losing consumers to competitors.\nSachdeva adds: “With multiple options of beverages, consumers have become more experimental and less loyal to brands, thereby compelling the manufacturers to continuously innovate to retain their consumers along with keeping affordability factor in mind.”\nThe recent RTD beverage launches will not only addresses consumers’ health concerns but also seems to capture the spirit of the times with the emotional value. For instance, beverage manufacturers are developing more personalised products targeting the distinct needs of specific consumer cohorts. However, brands need to strategise on how to retain their appeal post-COVID-19.\nSachdeva concludes: “While it is difficult to anticipate the full extent of the changes COVID-19 will trigger, beverage companies are trying their best to keep the category alive and vibrant while coping with the pandemic challenges.”\nCheck these articles out:", "pred_label": "__label__POS", "pred_score_pos": 0.9888706207275391}
{"content": "The vent stack in a residential building is an imperative part of the drainage system, and when it breaks down, the results can be disastrous. Without the vent stack maintaining the atmospheric pressure in the pipes, residents can experience leaking sewage and rainwater in their apartments and outside of the building, resulting in stagnant pooling water and hazardous conditions. If you own or reside in a residential building, proper maintenance to the vent stack can mean the difference between water damage and unhealthy conditions and enjoying a dry, clean environment.\nNuFlow Oklahoma offers an innovative way to ensure that the vent stack in your building stays in excellent shape. We can help you avoid a pricey bill for property damage from a faulty stack. The best part is, as a non-invasive repair method, vent stack lining is a contemporary way to replace existing stacks without the hassle of digging up flooring, breaking through infrastructure, or disturbing landscaping. You’ll save money on property remediation costs and labor, thanks to this simple, modern repair method.\nDuring vent stack lining, one of our licensed technicians will insert a high-definition camera into the stack to examine the conditions inside through an existing access point. This access point will be used to perform the entire process, eliminating the need for excessive damage to the building. If necessary, the stack will be flushed or cleaned to remove debris. A fiberglass liner is then inserted with a winch cable through the vent pipes. The end is secured with nylon straps and the liner is inflated and cured with UV light until it hardens. After the liner has hardened into place, the installation equipment is removed. The new vent stack will be up and running and ready to service the building.\nWhen it’s time to inspect or repair your vent stack, you can trust NuFlow Oklahoma. As specialists in non-invasive pipe lining services, we have the experience, expertise, and equipment to perform lasting vent stack repairs at your property.", "pred_label": "__label__POS", "pred_score_pos": 0.8243456482887268}
{"content": "The range of the California Halibut, Paralichthys californicus, spans three biogeographic provinces along the coastline of Alto (United States) and Baja (Mexico) California. To assess population genetic structure of the California Halibut, we analyzed mitochondrial cytochrome b sequences from 375 individuals across a large portion of its native range. Nucleotide diversity was consistently low among sampling sites (π = 0.0026 ± 0.0017), while haplotype diversity was consistently high (h = 0.77 ± 0.024). We found that California Halibut were genetically homogeneous across sampled sites with an overall Φst = 0.0030 (p = 0.22). We saw no evidence of genetic discontinuities at two previously recognized marine phylogeographic breaks in the Los Angeles region or across the California Transition Zone at Point Conception. We conclude that California Halibut are genetically homogeneous and experience substantial gene flow, at least over evolutionary time scales.", "pred_label": "__label__POS", "pred_score_pos": 0.8323062062263489}
{"content": "A Look Into Consumer Defensive Sector Value Stocks What Defines a Value Stock?\nA value stock is traditionally defined in terms of how investors in the marketplace are valuing that company’s future growth prospects. Low P/E multiples are good base indicators that the company is undervalued and can most likely be labelled as a value stock.\nBelow is a list of notable value stocks in the consumer defensive sector: Big Lots(NYSE: BIG) - P/E: 5.66 Ingles Markets(NASDAQ: IMKTA) - P/E: 8.08 Adtalem Glb Education(NYSE: ATGE) - P/E: 8.18 Mannatech(NASDAQ: MTEX) - P/E: 7.77 Pingtan Marine Enterprise(NASDAQ: PME) - P/E: 5.02\nMost recently, Big Lots reported earnings per share at 1.26, whereas in Q4 earnings per share sat at 2.39. Its most recent dividend yield is at 3.08%, which has decreased by 2.19% from 5.27% in the previous quarter.\nIngles Markets has reported Q2 earnings per share at 1.99, which has increased by 128.74% compared to Q1, which was 0.87. Its most recent dividend yield is at 1.64%, which has decreased by 0.39% from 2.03% in the previous quarter.\nThis quarter, Adtalem Glb Education experienced an increase in earnings per share, which was 0.57 in Q2 and is now 0.81. Adtalem Glb Education does not have a dividend yield, which investors should be aware of when considering holding onto such a stock.\nMannatech’s earnings per share for Q1 sits at 1.15, whereas in Q4, they were at 0.87. The company’s most recent dividend yield sits at 3.39%, which has increased by 0.29% from 3.1% last quarter.\nMost recently, Pingtan Marine Enterprise reported earnings per share at 0.1, whereas in Q4 earnings per share sat at -0.01. Its most recent dividend yield is at 1.47%, which has increased by 0.49% from 0.98% in the previous quarter.\nThe Significance: A value stock may need some time to rebound from its undervalued position. The risk of investing in a value stock is that this emergence may never materialize. © 2020 Benzinga.com. Benzinga does not provide investment advice. All rights reserved.", "pred_label": "__label__POS", "pred_score_pos": 0.9564401507377625}
{"content": "Efforts in the U.S. to create a dedicated pathway for fintechs to acquire bank charters made little progress, until recently.\nFor years, some fintechs had been exploring alternatives that now seem more viable: seeking industrial loan company (ILC) charters or joining so-called sandboxes established by state regulators — a path once considered the only option for fintechs while a federal bank charter remained in limbo. However, several recent regulatory changes will create a more open, albeit bumpy, road for fintechs to become banks.\nIn March, the Federal Deposit Insurance Corp. made two key moves. It first proposed a new standard for ILC charter applicants that would require parent companies to provide liquidity and capital support for their ILC subsidiaries, as well as meet new recordkeeping and reporting standards. A day later, the FDIC approved the ILC charter applications for small-business payments giant Square and Nelnet, a student loan servicer. The action made Square the first fintech to receive federal deposit-insurance approval to form a bank.\nIf the FDIC’s proposal goes into effect, fintechs could be well positioned to acquire ILC charters so long as they meet the new reporting requirements; provide a rescue plan for injecting liquidity if needed; and gain support from state regulators.\nKeep reading on American Banker.", "pred_label": "__label__POS", "pred_score_pos": 0.9594153165817261}
{"content": "The Q1 reporting period in China reflected the immediate devastation of mobile commerce before lockdowns turned the tides.\nThe Q1 2020 figures for China’s third-party mobile payment market, published by independent market research firm, iResearch have revealed some expected trends.\nWith a dominant share of 55.4%, Alipay remains in the lead as China’s largest third-party mobile payment company, followed by Tenpay (which is Tencent’s WeChat Pay + QQ Wallet) with 38.8%.\nAlipay has continued to increase its mobile payment market share for four consecutive quarters since Q1 2019.\nAmid the COVID-19 outbreak during the reporting period, China saw a decrease in third-party mobile payment transactions for the first time, at RMB53.2 trillion—a 4% drop compared to the same period in 2019.\nWith the release of the Q1 report, iResearch pointed out that future growth opportunities in China lie with the third-party payment providers’ capability to offer business clients integrated “payment + technology” solutions, instead of competing just on payment volume.\nPayment is not the end game\nEarlier in March, Alipay had announced a three-year plan to support the digital transformation of 40 million service providers in China. It committed to provide a platform for comprehensive digital daily life services, and a go-to app for consumers to find service providers to help meet their daily needs.\nWhen asked about its view on the mobile payment market share, Alipay’s spokesperson emphasized that “payment is not the end game, but the beginning of a wide range of services that enrich daily life. We are dedicated to supporting the digital transformation of the services industry by leveraging our technologies, instead of just focusing on payment market share.”\nThis official sentiment reflects the company’s business model that aims not only to provide payment solutions but also, to provide a comprehensive digital suite of technologies, including payment, to service providers.", "pred_label": "__label__POS", "pred_score_pos": 0.9829058051109314}
{"content": "Fraudsters ready for 2014 festive season\nWith credit card fraud and Internet scams an ever-present threat across the globe, South African consumers need to be particularly cautious during the run-up to the 2014 festive season.\nAccording to Richard Keymer, head of pre-sales at SecureData Africa, phishing remains the most common way in which South Africans inadvertently disclose their personal information online.\nThe victims get caught by fraudsters who pose as a financial institution and circulate an e-mail that appears to be from a legitimate site such as a user's bank, but, in fact, it comes from an external party masquerading as the financial organisation, he says.\nAccording to an article by Webber Wentzel, just under 100 SIM swap fraud cases were reported in 2011, and this increased to just under 1 000 cases in 2013, reflecting a 900% growth.\nKeymer notes SIM swap fraud attempts to undermine two-factor authentication methods. He argues that while receiving a one-time-PIN SMS is not the most secure second-factor authentication, it reduces instances of this type of fraud, though it has gained notoriety due to the fact that it is cheap and easily deployed to a large client base.\nThe banks notify the user when a beneficiary is being created on their account and require this PIN before proceeding. In the event that the SIM swap has been performed, the hacker would now receive this notification and PIN to their device, he explains.\nThe use of this as a fraud method in South African banks hit the media in the middle of last year, says Keymer.\nKeymer notes the banks and the cellular networks have taken measures to prevent and inform users of these attacks. For example, he says, users will now receive a notification of intent to perform a SIM swap to the existing SIM before this is completed.\n\"South African banks and mobile operators use SMS as an effective communication tool, and notification would often be sent to inform the user,\" he notes. He advises if any e-mail or SMS is received, it is recommended that users contact the service provider immediately.\nKeymer believes users should initiate contact with the service provider and query the alert. He points out all too often users get contacted and dismiss the alert based on contact from the fraudster notifying the user that there was a technical issue and it has now been resolved.\n\"It is worth mentioning this SIM fraud is only a component of the hack, and a username and password would still need to be compromised, and this is typically done through phishing, but could be done through malware and network hacking,\" he concludes.", "pred_label": "__label__POS", "pred_score_pos": 0.6768189668655396}
{"content": "Comment Opportunity: Speak Out to Preserve Access to SNAP, School Meals USDA is currently requesting comments on a proposed rule that would undermine SNAP’s broad-based categorical eligibility, adding new barriers to access SNAP benefits and eliminating direct certification of children in school meals programs. Currently, categorical eligibility allows more families to readily access nutrition assistance by simplifying SNAP's asset and income tests. Should this proposed rule be implemented, nearly 3 million SNAP participants and approximately 500,000 children receiving school meals will be ineligible to continue receiving fundamental nutrition assistance.\nThe proposed rule is open for public comment until September 23. NWA has released template comments to support WIC staff and agencies in responding to the proposed rule. Should you have any additional questions, please reach out to Brian Dittmeier, Senior Public Policy Counsel, at bdittmeier@nwica.org.\nFour Lawsuits Challenge Final Public Charge Rule Last week, the Department of Homeland Security announced the final rule on public charge.The final rule expands limitations on legal immigrants, penalizing individuals who are seeking legal status if they accessed SNAP, Medicaid, or housing subsidies. WIC is not included in the final rule.\nLast Tuesday, San Francisco and Santa Clara Counties filed the first of four legal challenges against the rule. Over the course of the week, additional lawsuits were brought by eighteen State Attorneys General and advocate groups, including healthcare providers. The states challenging this policy change include: Washington State, California, Colorado, Delaware, Illinois, Maine, Maryland, Massachusetts, Michigan, Minnesota, Nevada, New Jersey, New Mexico, Oregon, Pennsylvania, Rhode Island, Virginia, and the District of Columbia.\nThe final public charge rule is due to go into effect on October 15. This litigation could delay implementation of the policy change, if the courts grant a temporary stay.\nNWA has created resources to assist clinics with counseling concerned participants. The updated resources included NWA’s FAQ documents on public charge, with translations in both Spanish and Chinese. Lastly, you can also view NWA’s press release regarding the final rule here.\nThe August Recess is a Perfect Time to Connect with your Member of Congress Both the House and the Senate are on recess for the entire month of August, making this a perfect time to connect with your member of Congress. As they meet with key constituents in their communities, legislative staffers are considering key WIC priorities, including 2020 appropriations funding levels and pending proposals for Child Nutrition Reauthorization.\nLast week, the South Nutrition Center WIC Program, hosted Congressman Jim Cooper (D-TN) at their WIC clinic. In celebration of National Breastfeeding Month, the Congressman accepted an invitation to visit the WIC clinic to see first-hand how the program helps and supports Davidson County moms with breastfeeding. He received a tour of the facility, and learned about the Breastfeeding Peer Counselor Program.\nDuring this recess, NWA encourages you to connect with your member of Congress and set up clinic visits. Setting up these visits allows your legislator or staffer to see the excellent work you’re doing every day, as well as increase their knowledge of this vital public health nutrition program. If you are unsure of how to set up a WIC clinic visit, please refer to NWA’s advocacy toolkit section on contacting your elected official, or reach out to Kirsten Kelley, State Public Policy Associate, at kkelley@nwica.org.\nLegislators Seek to Protect Children from ICE Detention Senator Jeff Merkley (D-OR) and Rep. Grace Meng (D-NY) introduced the Stop Cruelty to Migrant Children Act, a new bill that would enact new requirements for the health, safety, and well-being of children and families that are in federal immigration detention. Senator Merkley is a recipient of the NWA Leadership Award for his steadfast commitment to WIC and his work to promote breastfeeding. NWA has endorsed this new bill, which would ensure that any infant or child in federal custody is fed three meals a day that align with the WIC and school meals nutrition standards.\nThe bill more broadly limits the detention of children for extended periods of time, consistent with the Flores precedent that encourages quick release of children into family or community settings.\nNWA has spoken out on the needs of migrant infants and children. Another example of the current system's flaws was exposed earlier this month, when a breastfeeding mother was detained during an ICE raid at a food processing plant in Mississippi. After eleven years in the United States, she has been separated from her three children - including a four-month-old infant - for 12 days at a facility nearly 200 miles away. She has stated that she is in pain from being separated from her children, as well as not being able to pump. NWA will continue to monitor the detention of migrant women and children and advocate for more humane conditions that adequately address their nutrition and health needs.", "pred_label": "__label__POS", "pred_score_pos": 0.8445906043052673}
{"content": "Not all volcanoes are quickly explosive. Some spew steady rivers of gloppy, gradual-moving lava for millennia on close, like people in the Hawaiian or Galápagos islands.These are what volcanologist Michael Stock...\nCOVID-19 triggers a strong immune reaction in most people today. Still various current scientific studies noticed that the quantities of antibodies in individuals recovering from the virus surface to drop...\nThis website uses cookies to improve your experience. We'll assume you're ok with this, but you can opt-out if you wish. Cookie settingsACCEPT\nPrivacy & Cookies Policy\nPrivacy Overview\nThis website uses cookies to improve your experience while you navigate through the website. Out of these cookies, the cookies that are categorized as necessary are stored on your browser as they are essential for the working of basic functionalities of the website. We also use third-party cookies that help us analyze and understand how you use this website. These cookies will be stored in your browser only with your consent. You also have the option to opt-out of these cookies. But opting out of some of these cookies may have an effect on your browsing experience.\nNecessary cookies are absolutely essential for the website to function properly. This category only includes cookies that ensures basic functionalities and security features of the website. These cookies do not store any personal information.\nAny cookies that may not be particularly necessary for the website to function and is used specifically to collect user personal data via analytics, ads, other embedded contents are termed as non-necessary cookies. It is mandatory to procure user consent prior to running these cookies on your website.", "pred_label": "__label__POS", "pred_score_pos": 0.840018630027771}
{"content": "Tips On How To Stimulate Your Dog's Appetite\nIn Dog Food | Written by Emily White\nA pet dog losing its appetite is not an uncommon thing. However, as common as the occurrence may be, it should be dealt with immediately. A dog should eat at least twice a day.\nBe sure to watch the quantity your dog consumes on a daily basis. Experts and veterinarians always advice dog owners to learn their dog’s behavior. This way, you can quickly spot when something is wrong.", "pred_label": "__label__POS", "pred_score_pos": 0.5606058835983276}
{"content": "Despite weaknesses, the new sub-compact SUV has the potential to bring the Japanese car maker back into the ...\nIndia’s homegrown Self-drive mobility start-up Revv today announced its initiative to offer cars at zero fee to assist healthcare workers amid the coronavirus outbreak.\nAccording to the official release, in times when healthcare workers continue to fight the pandemic, the unavailability of public transport options has made their daily commute to hospitals more difficult. Revv believes that with this initiative the problem of commuting could be solved.\nThis service is available in 5 metropolis - Delhi, Bengaluru, Mumbai, Chennai, and Pune. In each of these cities, Revv promises to make its current fleet of cars available, free of charge, to healthcare workers currently engaged in active duty at a hospital, upon submission of relevant ID proof. Revv will mobilize 1000+ cars to start with and include more as the need escalates.\nIn each of the 5 cities where Revv is providing this service, healthcare workers can reach out to Revv to place a booking. Revv will also add the service to its website and apps soon. After placing the booking, the healthcare worker can pick up the car from Revv’s delivery centers, and use it entirely free of charge. The Delhi-based company will require the user to share a copy of his proof of work (such as the hospital ID card) at the time of placing the booking. Revv mentioned that all the cars would be sanitized before handover.\nAccording to Revv’s Co-founders, healthcare workers battling the COVID-19 crisis at the frontline are the true heroes, and several of them are facing challenges with their commute to hospitals because of no availability of public transport. This is the least that Revv can do for them.\nThe cofounders, in a joint statement, said: “We’re inviting partners across these cities to help us accelerate this. For example, In Bengaluru, we are partnering with a 12,000 strong citizen volunteer group, to facilitate the distribution of these cars to healthcare workers that they are engaged with.”", "pred_label": "__label__POS", "pred_score_pos": 0.8082857728004456}
{"content": "Yearn Finance is currently the fastest-growing decentralized finance (DeFi) protocol in the crypto space.\nThis growth reflects on the project’s governance token (YFI) that rallied from about $1,000 a couple of months ago to highs of nearly $40K set yesterday.\nThe project personifies the desire of DeFi enthusiasts to cannibalize Centralized Finance (CeFi) and make financial services accessible to everyone.\nYearn Finance was designed by its founder Andre Cronje to give investors access to the most profitable yield farming opportunities.\nThe project has quickly gained momentum amongst crypto traders, mainly due to its automated liquidity mining and yield farming strategies.\nSince the project became a hit with investors, its native token YFI has surged massively in value; it outperformed BTC as it hit $16K on Aug 20.\nOver the past week, YFI leapt even higher, eventually reaching over $30,324 on Aug 29. The very next day, YFI posted an all-time high (ATH) price of $39K before correcting lower.\nAt the time of this article’s writing, YFI/USDT hovers around $33,954 with the total value locked (TVL) within the Yearn Finance pools now approaching the $1 billion mark.\nYFIUSDT Price Chart | Source Tradingview\nWhat’s Behind YFI’s Explosive Growth?\nYearn Finance has primarily gained popularity due to its ability to aggregate yields from other lending protocols. YFI holders can also use their tokens to vote on proposals for the project’s improvements.\nYearn Finance creator Andre Cronje initially designed the platform to work as a yield automation tool, but the protocol has quickly evolved into a stack of various DeFi products.\nIt offers lucrative features, such as automated liquidity mining strategies and the trading of stablecoins, including DAI with up to 1,000x leverage.\nOn Aug 28, top leading DeFi platform Aave announced the listing of YFI onto its protocol. The listing provided YFI with some positive price pressure that led to the recent price surge over the weekend.\nYFi holders can now earn further yields on their YFI and access simple Aave loan liquidations. What’s more, the protocol recently revealed plans to launch a new form of permissionless insurance dubbed “yinsure.finance.”\nThe imminent release of yInsure caused YFI to rally by approximately 40% in 24 hours, outperforming most other token assets in the market.\nHow Far Can Yearn Finance Go?\nYFI managed to hit an ATH price of $39K this past week after posting two previous peak values of $27K and $32,843 on the same day.\nThe impressive momentum has gained the attention of many prominent personalities in the crypto and DeFi sectors, with some suggesting that YFI’s rally is just getting started.\nFor instance, the CEO of Bitmex, Arthur Hayes, tweeted on Aug 30 that YFI can climb as high as $100K.\nDespite the current hype surrounding YFI, traders should deploy suitable stop losses and low leverage when trading derivatives platforms.\nThese precautionary steps could help mitigate heavy capital losses in case YFI corrects hard in the near term.", "pred_label": "__label__POS", "pred_score_pos": 0.8149368166923523}
{"content": "Uncover Bipolar Disorder through a visual journey.\nFor the last three years, Dr. Christophe Lambert PhD and an expansive team of researchers have worked on a comprehensive and profound study into Bipolar Disorder. Now, combining a wealth of research, the latest analytics, and personal insights, this graphic novel examines their findings.\nUsing big data analysis of over a million medical claims, as well as the personal lived experiences of those diagnosed with Bipolar, this book investigates the impact of Bipolar Disorder on the lives of those suffering with it, the mania and depression which are often initially misdiagnosed, and the treatment protocols which have failed to find a uniform, one-size-fits-all approach.\nThis book is a must-read for anyone looking to understand more about Bipolar Disorder and the millions of people who live with it every day.\nYou can order it on Amazon at this link or download it it for free below.", "pred_label": "__label__POS", "pred_score_pos": 0.7513328790664673}
{"content": "Abstract\nMetal dependent protein-based assemblies derived from the cartilage oligomeric matrix protein (C) coiled-coil domain (His\n6-C) and two variants with mutation at position 40 (His 6-T40A) and 44 (His 6-L44A) are explored. All proteins have an N-terminal hexahistidine tag (His 6) that interacts with divalent metal ions Zn(II) and Ni(II). Binding to Zn(II) confers enhanced helical structure and stability, while Ni(II) promotes aggregation. Surprisingly, His 6-L44A undergoes a conformational switch from unstructured to α-helix in the presence of Zn(II). Both His 6-C and His 6-T40A further assemble into discrete nanofibers that appear to be stabilized by Zn(II) in which the fiber formation is dictated by the α-helical content. Because Ni(II) promotes aggregation, the proteins visibly cluster, forming large fiber mats in the case of His 6-C and His 6-T40A or aggregated structures as observed for His 6-L44A. Due to the unique pentameric assembly of the proteins, recognition of a small molecule within the pore is assessed using curcumin as the guest molecule. In the presence of Zn(II), there is enhanced binding to curcumin, while the addition of Ni(II) causes a loss in binding. It is shown that metal binding serves as a trigger to control the conformation of the proteins, affecting the nanoscopic fibrous assemblies and small molecule recognition abilities. Keywords coiled-coils fibers metals self-assembly small molecule recognition stimuli-responsive materials ASJC Scopus subject areas Chemistry(all) Materials Science(all) Condensed Matter Physics", "pred_label": "__label__POS", "pred_score_pos": 0.6549798846244812}
{"content": "The architectural facade addresses and enhances the space of the city, while displaying, or dissembling, interior arrangements. In this book, Charles Burroughs tracks the emergence of the facade in late medieval Florence and then follows the sharply diverging reactions of Renaissance architects to new demands and possibilities for representation in both residential and governmental contexts. Understanding the facade as an assemblage of elements of diverse character and origin, Burroughs explores the wide range of formal solutions available to architects and patrons. In the absence of explicit reflection on the facade in Renaissance architectural discourse, Burroughs notes the theoretical implications of certain celebrated designs, implying mediation on the nature of architecture itself and the society it serves and represents, as well as on the relationship between nature and culture.", "pred_label": "__label__POS", "pred_score_pos": 0.7726529836654663}
{"content": "If you're someone who suffers from anxiety, you know how pervasive, distracting, and frustrating overthinking things can be. Even if you are able to manage your anxiety, it's common for thoughts to come creeping back in, which is why it can be useful to know somehacks tostop yourself from overthinking. Discovering good habits and mental tricks is key when it comes to managing anxiety and intrusive thoughts, especially when you find yourself ruminating frequently.\n\"We all have a tendency to overthink things, especially when it comes to decision making,\" psychotherapist Kelley Kitley tells Bustle. \"We want to make sure we make the 'right' decision and therefore play out 10 different scenarios. However, this can lead to anxiety, and ultimately, indecision. When people engage in overthinking, they may suffer from insomnia because they are laying in bed at night overthinking. ... They may struggle to connect in relationships because they are distracted and not present due to overthinking.\"\nWhile you may have a handle on other symptoms of anxiety, if you've found that overthinking has taken over you brain and is impacting your life, try out some of these seven hacks that experts recommend to prevent you from being in your head too much.", "pred_label": "__label__POS", "pred_score_pos": 0.933515191078186}
{"content": "The hard work of good data analysis is often surrounded by an array of glamourless, mundane, and underestimated processing steps.\nThese requisite steps can include retrieving, validating, cleansing, blending, enriching data from disparate and distant data sources, and then visualizing, delivering and archiving the analysis results.\nA good data integration strategy is key to building a strong analytics function in your organization.\nCheck out our webinar where we describe how to effectively nestle your analytics in a data integration workflow that protects it from changes in data size, structure, quality, format and location. See how truly understanding your source data and its integration journey will transform your results.\nKevin Scott is CloverDX's Senior Consultant, where he works with customers on complex data consultancy projects with, helping them to succeed on their journey and overcome data challenges.", "pred_label": "__label__POS", "pred_score_pos": 0.80600905418396}
{"content": "Public Confidence and Debt Management: A Model and A Case Study of Italy\nHigh debt countries may face the risk of self-fulfilling debt crises. If the public expects that in the future the government will be unable to roll over the maturing debt, they may refuse to buy debt today and choose to hold foreign assets. This lack of confidence may then be self-fulfilling. This paper argues that under certain conditions, the occurrence of a confidence crisis is more likely if the average maturity of the debt is short. In the contrary, a long and evenly distributed maturity structure may reduce such a risk. We consider the recent Italian experience from this perspective. In particular we ask whether recent developments in the market for government debt showy signs of unstable public confidence, and of a risk premium.", "pred_label": "__label__POS", "pred_score_pos": 0.8461329340934753}
{"content": "One of the key components of an effective home energy audit is infrared thermography. Infrared thermography (or infrared imaging, infrared diagnostics, a rose by any other name...) consists of a thorough visual inspection of a home, including the basement, attic, and all the nooks and crannies, with an infrared camera or another infrared assessment device. It essentially takes the guess-work out of pinpointing the drafts and the leaky spots within a home — registering, as it will, the exact temperature of various spots within the home, and, depending on the device used, providing you, the homeowner, with a precise visual representation of the imperfections in your home's thermal envelope.", "pred_label": "__label__POS", "pred_score_pos": 0.9449979066848755}
{"content": "Like many other forms of cancer, pancreatic cancer can spread locally to blood vessels and surrounding organs such as the stomach. Cancer cells can also break away to affect more distant sites, such as the liver, lungs, and lymph nodes. Pancreatic cancer is one of the most challenging diseases physicians face today because it is difficult to diagnose early and responds poorly to treatment. Despite the fact that these secondary tumors affect sites other than the pancreas, they are still considered and treated as pancreatic cancer.\nContinue Learning about Pancreatic Cancer Treatment\nImportant: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.", "pred_label": "__label__POS", "pred_score_pos": 0.6655422449111938}
{"content": "In my 6 ½ years working for\nHawaii Home + Remodeling, hundreds of homeowners, builders, designers, architects and suppliers have shared their expertise and creativity with me.\nI’ve learned what it takes to become a homeowner in Hawaii and bought my first place. I’ve seen how to make the most of a small space and purchased size-appropriate furniture for my condo. I invested in pieces that are sustainably sourced and crafted, feeling confident in the quality. I plan to upgrade my flooring to luxury vinyl tile for its durability, and daydream of one day updating my kitchen cabinets. And if I ever move into a home with a yard, I know where to turn for landscape design and hopefully even a pool. All of this was inspired by the people I’ve connected with through my work at the magazine.\nThis has truly been my dream job come true. As I turn the page to the next chapter of my career, I want to thank everyone who has shared this journey with me: my talented colleagues, driven builders, creative designers, innovative architects, knowledgeable suppliers and passionate homeowners. It has truly been a pleasure working alongside each of you.\nA home is so much more than a place to live. It is where we grow, as individuals and as families, and it should\nfeel like home. I hope you continue to find incredible inspiration and ideas in the magazine, as I have over the years. It’s been an honor to bring you stories of Hawaii home upgrades, renovations and new builds. I look forward to reading Hawaii Home + Remodeling for years to come, and I hope you will too. Maybe one day, our homes will be featured in the magazine.\nBest wishes always,\nStephanie Silverstein, Editor stephanies@hawaiihomemag.com", "pred_label": "__label__POS", "pred_score_pos": 0.727350115776062}
{"content": "This is an older question but things have changed. Its a common misconception on what the contribution cap is. A few things.\nIn 2014, the IRS did not adjust the maximum contribution from the previous year which include 401(k) accounts, 403(b) accounts, most 457 plans, and Thrift Savings Plans, will be $18,000, up $500 from $17,500.\nSavers and investors aged 50 or older can take advantage of a catch-up contribution. In 2015, taxpayers who meet this age-based criterion can contribute an additional $6,000 above the regular maximum of $18,000, thus you can contribute a maximum of $24,000 into these tax-advantaged accounts.\nThe total contribution limit, including employer contributions, has increased to $53,000\nYou can actually contribute up to 53k (including matching) so the exact amount you contribute from your actual income may end up being more or less than 24k. If you get a poor employer match you can actually contribute more but it would go in as after tax dollars and not claim the tax deduction.\nNote: after tax does NOT equal Roth.\nHowever if your a high salaried individual you can use this as a potential loop hole for funding a Roth IRA. Chances are if your making enough money to contribute 53k Total Contributions then your not going to qualify for a roth. However once you retire (or possibly before depending on the plan withdraw terms) you can roll the after tax money into a Roth IRA. This is a gray area on the tax policy. The IRS may come back and change their mind about this. If considering this option talk to a tax adviser.", "pred_label": "__label__POS", "pred_score_pos": 0.5168125629425049}
{"content": "Articles by Anne Marie van Swinderen\nGuest Articles\nTuesday\nNovember 3 2020 Keeping Finance in the Family: How Intra-Family Accounts Can Help Low-Income Customers During COVID-19 – and Beyond\nBanks in emerging countries often struggle to generate active usage of the accounts they offer to young people. Yet as Anne Marie van Swinderen at L-IFT points out, financial diaries research has shown that young people save frequently and significantly – especially when their earnings rise. She explores how intra-family accounts could help banks serve this challenging demographic during COVID-19 and in the longer term – while also expanding their financial services to other members of the family.", "pred_label": "__label__POS", "pred_score_pos": 0.8581058382987976}
{"content": "National Colorectal Cancer Awareness Month, held in March each year, offers healthcare providers who care for patients with diseases of the colon and rectum a valuable opportunity to educate their community about these diseases and promote awareness of the importance of colorectal cancer screening, prevention, and treatment. These efforts may also provide a window into the profession and encourage others to consider careers in the field of colon and rectal surgery.", "pred_label": "__label__POS", "pred_score_pos": 0.9765996932983398}
{"content": "Cylert is the brand name of the generic medication pemoline. Cylert is used to help in the treatment of children who are dealing with attention deficit hyperactivity disorder (ADHD). It is often recommended that Cylert only be prescribed as part of a comprehensive treatment plan that offers both psychological and educational support to help the child to become more stable. In its generic form, Cylert is a white, tasteless, odorless powder that is relatively insoluble in water, chloroform, ether, acetone and benzene.\nCylert is subject to control under the Drug Enforcement Act as a Schedule IV drug. While the drug did not demonstrate a potential for self-administration in clinical animal trials, it is closely related to other psycho-stimulants that have a known dependence. This suggests that psychological and/or physical dependence and tolerance can occur with Cylert. There have also been isolated reports in the industry of transient psychotic symptoms occurring in adults following the long-term misuse of excessive oral doses of Cylert and its generic equivalent. As a result, it is imperative that the medication is given to emotionally unstable patients only when closely monitored as they may increase the dosage on their own initiative.", "pred_label": "__label__POS", "pred_score_pos": 0.5471524000167847}
{"content": "Philippines: Impact of COVID-19 on Micro, Small, and Medium Enterprises (MSMEs)\nThe extended community quarantine imposed by the government to contain the spread of COVID-19 has adversely affected MSMEs in the Philippines. This report outlines the impact of the pandemic on MSMEs and provides recommendations for policymakers to support their recovery.\nIndonesia has been the hotbed for FinTech innovations across the ASEAN region. However, like all other businesses, FinTechs in the country too have been struggling to cope with the Pandemic. In this study, we highlight the impact of the pandemic on FinTechs in Indonesia.\nCOVID-19: A harbinger of consumer behavior shifts among FinTech users\nThe blog analyzes the impact of the COVID-19 on two major categories of FinTechs—credit and savings FinTechs. We analyze the immediate impact of the pandemic and the ensuing regulatory changes on FinTechs along with some long-term changes in consumer behavior that can have a systemic adverse impact. We close by recommending data-driven measures that credit and savings FinTechs should take today to control and arrest such adverse changes in consumer behavior.\nAmid the COVID-19 crisis, agricultural activities in India were exempt from restrictions. However, the lockdowns led to various disruptions in the supply chain. This blog summarizes the impact of COVID-19 on different sub-sectors and highlights the measures the government took to address the problems of farmers.\nImpact of the COVID-19 pandemic on CICO agents- Uganda report\nThis report explores the impact of COVID-19 on CICO agents in Uganda. It also highlights the strategies agents adopted to stay afloat during the pandemic and provides recommendations for policymakers and financial service providers to support these agents better.\nWe are looking up to business correspondents in the pandemic; but what are they looking at?\nThe business correspondent (BC) network in India has become indispensable for last-mile financial service delivery across urban and rural centers. In light of the current pandemic, our note highlights the challenges BC agents face while providing services in far-flung unbanked areas.", "pred_label": "__label__POS", "pred_score_pos": 0.9966732859611511}
{"content": "Bacopa monnieri, also called brahmi, water hyssop, thyme-leaved gratiola, and herb of grace, is a staple plant in traditional Ayurvedic medicine.\nBacopa monnieri has been used by Ayurvedic medical practitioners for centuries for a variety of purposes, including improving memory, reducing anxiety, and treating epilepsy.\nBenefits -\nhave anticancer properties", "pred_label": "__label__POS", "pred_score_pos": 0.9448188543319702}
{"content": "A journey to “South”: Becoming third world women educators\nThesis\nLopes Duraes, Bruna. (2019)\nA journey to “South”: Becoming third world women educators[Thesis]. https://doi.org/10.26199/6gys-he10\nAuthors Lopes Duraes, Bruna Qualification name Doctor of Philosophy (PhD) Abstract\nThis thesis is an invitation to think about education as part of a progressive social movement. We, third world women educators, participate in a struggle over the politics of recognition and distribution. This thesis investigates the stories of five women teachers, including my own, who come from so-called third world countries. The research applies several theoretical perspectives on the lives of these women to assist me in understanding the experience of third world women teachers in times of change. The research draws on philosophical works of Henri Lefebvre, sociological perspectives of Dorothy Smith, and the cultural theory of Michel de Certeau and adopts a feminist neo-Marxist and cultural approaches as a way of explicating relations of power in the everyday, while articulating conceptual tools that challenges domination. This research comes from the perceived need to approach teaching differently (Sachs, 2016) and the thesis provides a platform through which to contribute to the ongoing debate in education by reimagining teaching differently as I undertake a journey “South” (Connell, 2007). I use “South” as a metaphor, to investigate the lived experiences of teachers who come from postcolonial nations, such as South America (Chile and Brazil) and South Africa. I represent these teachers’ “journeys” to Australia, as I critically engage with their stories of becoming teachers in this landscape. By undertaking an inquiry to South, this thesis challenges hegemonic forces in education, by representing the voices of third world women educators in education.\nKeywords third world countries; women teachers; neoliberal policies; narrative inquiry; institutional ethnography; responsibility; professionalism Year 2019 Publisher ACU Research Bank Digital Object Identifier (DOI) https://doi.org/10.26199/6gys-he10 Research Group School of Education Final version Publication dates 01 Jan 2019\nhttps://acuresearchbank.acu.edu.au/item/8v242/a-journey-to-south-becoming-third-world-women-educators\nDownload files 0total views 2total downloads 0views this month 2downloads this month These values are for the period from 19th October 2020, when this repository was created.", "pred_label": "__label__POS", "pred_score_pos": 0.5484495162963867}
{"content": "In a recent PwC innovation survey, seven out of 10 executives agreed that having a well-defined innovation process is key to building an innovation culture. But that is not easy, even for companies like Artefact, whose bread and butter is design and innovation.\nEven we, the experts, find it challenging to organize our inspiration without inadvertently losing ideas. We believe that ideas get stronger when we incorporate input from other disciplines, yet we have not found a consistent way to integrate feedback into the design process. Finally, while we constantly evolve the frameworks and tools that help us make decisions, over time we lose the background that led us on a certain path. Until now.\nToday, together with our sister company 10,000ft, we are unveiling 10,000ft Insights, a shared project space for creative teams and organizations. It enables easy collecting and sharing of ideas, facilitates timely and relevant feedback, and helps organizations retain knowledge in the ever-faster pursuit of innovation.\n10,000ft Insights is already amping up our work at Artefact. Both internal innovation initiatives and client collaborations benefit from what we can now deliver even better — stronger collaboration between teams, clarity and transparency in the design process, and ultimately, decisions, directions and successes we can confidently stand behind. Try it.", "pred_label": "__label__POS", "pred_score_pos": 0.542519211769104}
{"content": "The Canadian Energy Pipeline Association (CEPA) represents Canada’s transmission pipeline companies who operate approximately 119,000 kilometres of pipeline in Canada and 14,000 kilometres in the United States. CEPA members move approximately 1.2 billion barrels of liquid petroleum products and 5.4 trillion cubic feet of natural gas each year.\nCEPA’s mission is to continually enhance the operating excellence, business environment and recognized responsibility of the Canadian energy transmission pipeline industry through leadership and credible engagement between member companies, governments, the public and stakeholders. Our members’ relationships with Indigenous groups are a critical component to operationalizing this mission. These relationships span the entire country and continue to evolve as aspirations regarding reconciliation become reality. As leaders in the transportation of energy we recognize the value in building and maintaining mutually beneficial, long-term relationships with Indigenous groups through principled approaches to Indigenous relations.", "pred_label": "__label__POS", "pred_score_pos": 0.5190449357032776}