Condominium and Cooperative Law in Massachusetts
Cooperatives and condominiums are instances of "common interest" communities.
These are communities in which each resident rents or owns a residential unit. The residential units are part of a larger building, or complex of buildings, which are owned by another entity, such as a corporation or association. The residents are accountable for the upkeep of common areas, such as lawns and walkways. Rather than personally tending to these things, residents usually pay a fee that covers these necessities.
Merely viewing one of these communities from the outside (or inside) will not let you discern whether it's a cooperative or condominium community.
This is because there are no physical characteristics that can precisely distinguish one from the other. The major difference lies in the legal ownership arrangement. In a condominium community, the units are actually owned by the residents. The residents also collectively own the common areas, holding joint title to it. In a cooperative community, the buildings and land which make up the houses are owned by a single entity, and the individual units are often rented rather than owned by the residents.
Laws and Regulations Concerning Common Interest Communities in Nantucket, Massachusetts
Numerous Nantucket, Massachusetts laws affect common-interest communities. However, almost all of these laws govern real estate more generally, and there are very few laws written particularly for common interest communities. Such generally-applicable laws include zoning regulations, contracts, and the relations between landlords and tenants.
Generally, the rules established by the owner of the property, or the entity tasked with managing it, are going to have much more of a day-to-day effect on your life than any state laws governing these types of communities.
The land on which these communities sit is private property, so the owners have significant leeway when it comes to setting rules regarding what tenants can and can't do on the property. These rules generally govern things like noise levels, cleanliness, long-term guests, and pets. They are often designed with the goal of balancing residents' rights to a clean and quiet neighborhood, with their individual autonomy.
The enforceability of some of these rules may depend on Nantucket, Massachusetts's laws controlling relations between landlords and tenants.
Can a Nantucket, Massachusetts Attorney Help?
If you are in a dispute with your homeowners' association, a neighbor, or your landlord in Nantucket, Massachusetts, a reputable real estate lawyer may prove extremely helpful, if the dispute cannot be otherwise resolved.


Condominium and Cooperative Law in Wyoming
Cooperative and condominium communities are examples of a class of housing developments identified as "common interest communities."
They are communities where each individual or family resident rents or owns an unit which is part of a larger building, containing other, similar, residential units. The residents are accountable responsible for the maintenance of the common areas of their living areas, such as gardens, walkways, lawns, and swimming pools. They typically meet this responsibility by paying a monthly fee to support this maintenance.
Just looking at the outside (or inside, for that matter) of a condo or cooperative community, you likely can't tell which it is.
This is because there are no defining physical characteristics which are distinct to one type of cooperative community, but not the other. The significant differences aren't embodied in physical characteristics, but in the legal ownership arrangement governing the communities: in a condominium community, the residents own the units they live in. In a cooperative community, the units are rented.
Laws and Regulations Concerning Common Interest Communities in Laramie, Wyoming
Laramie, Wyoming likely has numerous laws and regulations concerning common interest communities. Nonetheless, these are mostly limited to the laws and regulations (zoning, land use, etc.) that concern all real estate owners.
In general, the procedures of the landowner or management board will have a much greater impact on the daily lives and conduct of residents than any state or local laws controlling condominiums or cooperatives.
The land that common interest communities occupy is typically private property. Therefore, the owners of the property are free to make certain rules governing what is and isn't allowed on it. A good manager or owner will typically make every effort to strike a balance between residents' freedom to do what they want in their homes, and the rights of their neighbors to a safe, clean, and reasonably quiet living space.
Some rules set by property owners or managers may not be enforceable, however. For instance, in Laramie, Wyoming, any rule which purports to exclude residents based on race, color, national origin, or religion will not be legitimate. There are likely some others, as well.
Can a Laramie, Wyoming Attorney Help?
If you are involved in an argument with your neighbor, in conflict with a zoning regulation, or in a dispute with your landlord, a reliable Laramie, Wyoming real estate attorney can help you prevail.


A business practice where a company owns its own supply chain. For example, owning the farms where hemp is grown, the barns where it’s stored, and the labs where it’s processed. This means that a vertically integrated company can ensure tighter quality control and maintain their core values and practices across all parts of the production process.
Vertical integration
Team Omni


Self-Ligating Braces
Self-ligating braces are similar to traditional braces, but they do not need elastics. This means less friction on the tooth, easier cleaning, less visibility, and fewer appointments to get your braces adjusted. They can use metal, ceramic, or clear brackets. A specialized clip helps the archwire guide the teeth.
Clear (Ceramic) Braces
These braces have clear or ceramic brackets. The clear brackets allow the tooth to show through, while the ceramic brackets mimic the color of the teeth, letting them blend in. These may be visually less prominent, but they have some drawbacks. Both can become discolored without diligent care, and ceramic braces can become chipped or broken.
Clear Aligners
Aligners are invisible when worn, removable, and more comfortable than braces since they sit flush against the teeth. Since they can be removed for a few hours each day, they make eating, drinking, brushing, and flossing easier. In most cases, they work faster than braces, and patients require fewer office visits.
Traditional Metal Braces
These are the braces you picture when you think about orthodontic treatment. Compared to versions of the past, they are smaller, lighter, and more effective. If you want to be creative, you can opt for colored elastics or even specially shaped brackets.


Vaccination and 30-day mortality risk in children, adolescents, and young adults Overview Research View All Overview abstract OBJECTIVE: This study evaluates the potential association of vaccination and death in the Vaccine Safety Datalink (VSD). METHODS: The study cohort included individuals ages 9 to 26 years with deaths between January 1, 2005, and December 31, 2011. We implemented a case-centered method to estimate a relative risk (RR) for death in days 0 to 30 after vaccination. Deaths due to external causes (accidents, homicides, and suicides) were excluded from the primary analysis. In a secondary analysis, we included all deaths regardless of cause. A team of physicians reviewed available medical records and coroner's reports to confirm cause of death and assess the causal relationship between death and vaccination. ESULTS: Of the 1100 deaths identified during the study period, 76 (7%) occurred 0 to 30 days after vaccination. The relative risks for deaths after any vaccination and influenza vaccination were significantly lower for deaths due to nonexternal causes (RR 0.57, 95% confidence interval [CI] 0.38-0.83, and RR 0.44, 95% CI 0.24-0.80, respectively) and deaths due to all causes (RR 0.72, 95% CI 0.56-0.91, and RR 0.44, 95% CI 0.28-0.65). No other individual vaccines were significantly associated with death. Among deaths reviewed, 1 cause of death was unknown, 25 deaths were due to nonexternal causes, and 34 deaths were due to external causes. The causality assessment found no evidence of a causal association between vaccination and death. CONCLUSIONS: Risk of death was not increased during the 30 days after vaccination, and no deaths were found to be causally associated with vaccination. Link to Article publication date published in


2018 was a record-breaking year for JAMK’s RDI activities, marking an increase of 19% compared to the previous year. External funding for RDI activities amounted to
€7.9M (€6.6M in 2017), marking a growth of approximately €1.3M compared to the previous year. As expected, the total volume kept increasing, reaching €11.0M (€9.4M in 2017). The RDI activities were more extensive than ever as international operations were strengthened and the operational volume remained at the target level throughout the entire year.
The RDI efforts developed with a focus on the strengths specified by JAMK’s strategy, including education and business expertise, bioeconomy, applied cybersecurity, multidisciplinary rehabilitation, and automation and robotics as an emerging field. The effectiveness of RDI activities was a particular area of effort. Other development areas selected based on an external evaluation of the RDI activities were also moved actively forward, especially those related to applied research and communications. The EduFutura co-operation with key partners, the University of Jyväskylä and the municipal education consortium was diverse. JAMK experts were actively involved in the development of the Kangas, Nova (new hospital) and Hippos areas.


Abstract
BackgroundCommunication failures involving test results contribute to issues of patient harm and sentinel events. This article aims to synthesise review evidence, practice insights and patient perspectives addressing problems encountered in the communication of diagnostic test results.MethodsThe rapid review identified ten systematic reviews and four narrative reviews. Five practitioner interviews identified insights into interventions and implementation, and a citizen panel with 15 participants explored the patient viewpoint.ResultsThe rapid review provided support for the role of technology to ensure effective communication; behavioural interventions such as audit and feedback could be effective in changing clinician behaviour; and point-of-care tests (bedside testing) eliminate the communication breakdown problem altogether. The practice interviews highlighted transparency, and clarifying the lines of responsibility as central to improving test result communication. Enabling better information sharing, implementing adequate planning and utilising technology were also identified in the practice interviews as viable strategies to improve test result communication. The citizen panel highlighted technology as critical to improving communication of test results to both health professionals and patients. Patients also highlighted the importance of having different ways of accessing test results, which is particularly pertinent when ensuring suitability for vulnerable populations.ConclusionsThis paper draws together multiple perspectives on the problem of failures in diagnostic test results communication to inform appropriate interventions. Across the three studies, technology was identified as the most feasible option for closing the loop on test result communication. However, the importance of clear, consistent communication and more streamlined processes were also key elements that emerged.Review registrationThe protocol for the rapid review was registered with PROSPERO CRD42018093316.


For a long time, the cure for diabetes type 1 and type 2 has relied on agonizing insulin shots for patients or insulin infusion via mechanical pumps. Regarding this, experts have been creating artificial pancreatic beta cells with the he…
In this report, LP Information covers the present scenario (with the base year being 2017) and the growth prospects of global Neuroprotective Products market for 2018-2023.
Neuroprotective Products consist of medications that can be used to protect or preserve the neuronal cells of the brain from degeneration, stress, and injury, which can impair cognitive functions.
Over the next five years, LPI(LP Information) projects that Neuroprotective Products will register a xx% CAGR in terms of revenue, reach US$ xx million by 2023, from US$ xx million in 2017.
This report presents a comprehensive overview, market shares, and growth opportunities of Neuroprotective Products market by product type, application, key manufacturers and key regions.
To calculate the market size, LP Information considers value and volume generated from the sales of the following segments:
Segmentation by product type:
- Cholinesterase inhibitors
- NMDA receptor antagonists
- Others
Segmentation by application:
- Alzheimer's disease
- Multiple sclerosis
- Others
This report also splits the market by region:
- Americas
- - United States
- - Canada
- - Mexico
- - Brazil
- APAC
- - China
- - Japan
- - Korea
- - Southeast Asia
- - India
- - Australia
- Europe
- - Germany
- - France
- - UK
- - Italy
- - Russia
- - Spain
- Middle East & Africa
- - Egypt
- - South Africa
- - Israel
- - Turkey
- - GCC Countries
The report also presents the market competition landscape and a corresponding detailed analysis of the major vendor/manufacturers in the market. The key manufacturers covered in this report:
- Genervon Biopharmaceuticals (Canada)
- NeuroVive Pharmaceutical (Sweden)
- Ceregene (USA)
- BHRPharma (Thailand)
- Neuren Pharmaceuticals (Australia)
- Allon therapeutics (Canada)
- Bionure Inc. (USA)
- ...
In addition, this report discusses the key drivers influencing market growth, opportunities, the challenges and the risks faced by key manufacturers and the market as a whole. It also analyzes key emerging trends and their impact on present and future development.
Research objectives
- To study and analyze the global Neuroprotective Products consumption (value & volume) by key regions/countries, product type and application, history data from 2013 to 2017, and forecast to 2023.
- To understand the structure of Neuroprotective Products market by identifying its various subsegments.
- Focuses on the key global Neuroprotective Products manufacturers, to define, describe and analyze the sales volume, value, market share, market competition landscape, SWOT analysis and development plans in next few years.
- To analyze the Neuroprotective Products with respect to individual growth trends, future prospects, and their contribution to the total market.
- To share detailed information about the key factors influencing the growth of the market (growth potential, opportunities, drivers, industry-specific challenges and risks).
- To project the consumption of Neuroprotective Products submarkets, with respect to key regions (along with their respective key countries).
- To analyze competitive developments such as expansions, agreements, new product launches, and acquisitions in the market.
- To strategically profile the key players and comprehensively analyze their growth strategies.


Johannesburg, 14 October 2020 - As Governments across the world implemented a range of measures to slow the spread of COVID-19, Chartered Accountants Worldwide members were there to provide support and resources.
Their work involved:
Direct contact at the highest levels with Governments to make recommendations and influence policy from a financial and business perspective. Seeking and providing clarity on business support initiatives designed to counter the impact of COVID-19. Reaching significant audiences of members, practice firms and other stakeholders through webinars, online guides, and social media to guide them through new legislation and business support.
Chartered Accountants Worldwide wanted to discover how its member institutes in Australia and New Zealand, Bangladesh, England, Scotland and Wales, Indonesia, Ireland, Pakistan, Singapore, South Africa, Sri Lanka and India had been working with their Governments to help them strategically plan their recovery. We published the findings on Charteredaccountantsworldwide.com.
In that article, we also highlighted how Governments are now experiencing higher levels of trust, as measured by the Edelman Trust Barometer. By taking swift action to support and engage with Governments, Chartered Accountants member institutes are helping to build and reinforce that trust, by showing leadership and influence, while highlighting their value to members and to the wider community.
In this article, we focus on the impact CAW member institutes made across their economies, the businesses in their countries, and their members.
Australia and New Zealand: CA ANZ
In Australia, CA ANZ’s COVID-19-related advocacy achieved a media reach of 4.4 million by the first week of May. And across Australia and New Zealand, their COVID Sharing Knowledge sessions for members achieved 30,000 registrations by the end of May.
CA ANZ advocated with the Federal Government for recognition of accounting as an ‘essential service’, and was part of a group of accountants and financial planners that successfully applied to Australia’s Securities and Investments Commission for regulatory relief. This resulted in more Australians getting the help they needed to understand the Federal Government’s COVID-19 economic packages, including early access to their superannuation.
Bangladesh: ICAB
The Bangladesh Government considered several recommendations from ICAB. This included supporting business and the economic recovery in the national budget and fiscal policy whilst another focused directly and indirectly on widening the tax net for revenue generation with an aim to achieve a higher tax GDP ratio. ICAB also proposed allocating sufficient budget to create a social safety net for low-income groups.
As part of serving society at large with useful information and guidance, ICAB arranged several seminars, press conferences and discussions with members and relevant stakeholders including key regulators and Government.
Ireland: Chartered Accountants Ireland
A key initiative of Chartered Accountants Ireland was the development and publication of “The Next Financial Year: Making Irish Business More Competitive.” This multi-disciplinary position paper considered how the Government in ROI and NI can simplify processes and remove red tape to support business recovery and expansion.
Many measures proposed by the policy have been adopted by both the Irish and UK Governments. Subsequently, Government Ministers and HMRC have acknowledged the important contributions Chartered Accountants Ireland have played during this COVID-19 pandemic.
Indonesia: IAI
InIndonesia, Micro, Small and Medium Enterprises (MSMEs) are among the hardest hit by the COVID-19 crisis, with 47% expected to experience significant disruption. Under the ‘IAI for Society’ banner, IAI actively equipped practising Chartered Accountants in accounting services firms with the latest know-how, focusing on building resilience and how to overcome uncertainties connected to the pandemic.
IAI also highlighted the role of Chartered Accountants as trusted advisors, especially those in the public sector, given their important role in overseeing the refocusing and realising of the state’s budget into COVID-19 initiatives.
Pakistan: Institute of Chartered Accountants Pakistan
ICAP held webinars to create awareness, give insights and educate participants on current issues including organisational resilience, business transformation, and the impact of COVID-19. These were extremely well received, reaching audiences of over 95,000.
To support members during the pandemic, ICAP made all of its study texts available online free of charge and arranged courier delivery of books to more than 3,000 students.
Singapore: ISCA
ISCA published technical guidance on audit and financial reporting issues arising from the pandemic. They held a series of advisory sessions for accounting practices to help them ensure business continuity safely during COVID-19. Together with Government agency, ISCA also co-organised a Virtual Career’s Fair for Accounting and Finance Professionals, which attracted more than 11,000 visitors in two weeks.
With the pace of digital transformation accelerating amid the pandemic, ISCA launched the SMP Programme with the support of Enterprise Singapore, a Government agency. This initiative aims to drive digitalisation, upskilling and internationalisation of Singapore’s SMPs.
South Africa: SAICA
Since South Africa’s lockdown took effect on 27 March, SAICA made 11 submissions on issues ranging from tax policy and compliance to relief bills and the national budget, at the request from regulators and standards setters. It also presented to the national parliament on the supplementary budget and held webinars to explain the Unemployment Insurance Fund process to its members.
SAICA served on the Ministerial Paying Tax Workgroup and the Labour Workgroup. Other advocacy efforts included submissions to Business for South Africa (B4SA) for relief negotiations and Unemployment Insurance Fund (UIF) labour relief, drafts of two tax disaster relief bills, regulations on “essential and permitted services”, and on the UIF Temporary Employee/Employer Relief Scheme (TERS) benefit regulations.
Sri Lanka: CA Sri Lanka
CA Sri Lanka took several initiatives to enhance the skill sets of its 6000 members. It contacted local chambers and the Government, offering support and services to restructure and resuscitate the economy.
It was also involved in the launch of a task force to identify economic segments where its members could offer help, including the SME sector, which accounts for over a million entities contributing over 50% of national GDP.
India: ICAI
Seeking to support its Government through these troublesome times, the ICAI has played a crucial role in creating awareness and implementing relief packages. Using its 1 million strong student and member community, the ICAI rallied financial donations to the Relief in Emergency Situations fund, in addition to continuing its influential participation in India’s efforts to create Atmanirbhar Bharat (a Self-Reliant India).
To keep its members up to date and maintain a minimalistic impact to small and medium practitioners, ICAI offered free support to the professional community. Using initiatives such as the DLH (Digital Learning Hub), they were able to grant free access to structured CPE hours, provide various webinars and virtual certificate courses.
UK: ICAEW (England and Wales)
ICAEW’s collaboration with the UK Government focused on fine-tuning the Government’s COVID initiatives for businesses and looking at how companies can reopen from lockdown while protecting the safety of staff at work and adapting physical workplaces for social distancing.
As well as working with the Government, ICAEW continued to engage with Opposition front bench spokespersons and key stakeholders on UK Parliamentary Committees.
UK: ICAS
Both UK and Scottish Governments had welcomed, listened and responded to a number of the matters that ICAS raised, particularly in relation to the fine-tuning of the job retention and income support schemes.
To help the Scottish Government to strategically plan its approach to the recovery, ICAS actively encouraged Chartered Accountants in key organisations across all sectors to ensure that their organisations responded to the proposed plan. ICAS also submitted its own response focusing on funding, accountability and scrutiny, sustainability and taxation.


Buying groups are under attack from competition authorities across Europe. Joint buying arrangements are aimed at strengthening participating companies' bargaining power towards their trading partners, usually resulting in lower prices or better quality for consumers. However, these buying arrangements must stay on the right side of the line between legitimate cooperation and anticompetitive collusion. Competition concerns may arise if the participating companies have a significant degree of market power or coordinate their conduct.
The European Commission and various national competition authorities are currently investigating several buying groups, as well as a number of potential buying cartels. Companies are well-advised to invite their procurement teams to their competition compliance training and to double-check whether their buying arrangements stay on the right side of the line.
Competition investigations into buying groups
The European Commission recently raided the premises of two French retail groups (Casino and Intermarché) as part of its investigation into whether these groups went beyond the purpose of their purchasing alliance and possibly colluded on consumer pricing and store networks. According to the Commission, the growing number of alliances in the food retail sector, alongside changes in alliance partners, have increased the risk of collusion.
The Commission's competition concerns about buying alliances seem to be shared by more European competition authorities. The Belgian competition authority is currently investigating a purchasing partnership concluded last year between Carrefour and Provera. According to a newspaper, the investigation was opened after suppliers complained about being forced to grant discounts to the purchasing alliance without any consideration. Similarly, the Czech competition authority has imposed a fine of CZK 164 million (approx. EUR 6.4 million) on the Rewe retail chains and Rewe Buying Group for abusing their significant market power by squeezing bonuses out of their suppliers. The German competition authority prevented a planned merger between purchasing cooperations in the furniture sector for fear of the new entity becoming too powerful, to the detriment of consumers and suppliers. The French competition authority is taking a closer look at the competitive impact of various supermarket purchasing alliances on the relevant markets for consumers and suppliers, while the Norwegian competition authority recently conducted a dawn raid in the grocery sector following its inquiry into purchasing conditions for grocery chains.
Buying cartels
Besides intensified scrutiny of joint buying arrangements, the number of investigations into buying cartels also appears to be on the increase. The Commission's investigations into potential anticompetitive conduct related to the purchasing of the chemical products styrene monomer and ethylene are still ongoing.
The Dutch competition authority (the ACM) has conducted dawn raids at various traders to investigate their involvement in a potential purchasing cartel in the agricultural sector. The ACM suspects the traders of coordinating the prices paid to farmers for their agricultural products. The investigation is part of a wider inquiry into potential anti-competitive conduct in the agricultural sector.
The German competition authority imposed fines totalling EUR 100 million on car manufacturers BMW, Daimler and Volkswagen for their alleged involvement in a steel purchasing cartel. According to the German competition authority, the car manufacturers regularly met with steel producers, forging companies and large systems suppliers to agree on uniform scrap and alloy surcharges. These surcharges represent a significant part of the long steel purchase prices. In contrast to more 'traditional' buying cartels, in this case both the purchasers and the suppliers were involved in the purchase price-fixing. However, the German competition authority opted to terminate its investigations against the suppliers
"for discretionary reasons".
Fines imposed for participating in a buying cartel can be substantial, as underlined by the General Court's recent rulings in the alleged car battery recycling cartel. The General Court reduced the fine imposed on one of the cartel participants, because the Commission, inter alia, failed to prove that the company had participated in the cartel for its entire duration. However, the Commission's novel fining approach in regard of the buying cartel was upheld. The Commission had departed from its general fining methodology and took account of the value of purchases, instead of sales, to determine the fine level. Since purchases are normally lower than sales in value terms, the Commission applied a 10% increase of the fine amount to ensure a sufficient deterrent effect. According to the General Court, the Commission's explanation was sufficiently substantiated for it to deviate from its general fining methodology [see our June 2019 Newsletter]. It therefore maintained the 10% fine increase.
Given these recent developments, companies are well-advised to double-check whether their buying arrangements stay on the right side of the line between legitimate cooperation and anticompetitive collusion. In addition, they should make sure to invite their procurement teams to their competition compliance training.
This article was published in the Competition Newsletter of December 2019. Other articles in this newsletter:


Bats are excellent models for studying the molecular basis of sensory adaptation. In Chiroptera, a sensory trade-off has been proposed between the visual and auditory systems, though the extent of this association has yet to be fully examined. To investigate whether variation in visual performance is associated with echolocation, we experimentally assayed the dim-light visual pigment rhodopsin from bat species with differing echolocation abilities. While spectral tuning properties were similar among bats, we found that the rate of decay of their light-activated state was significantly slower in a nonecholocating bat relative to species that use distinct echolocation strategies, consistent with a sensory trade-off hypothesis. We also found that these rates of decay were remarkably slower compared with those of other mammals, likely indicating an adaptation to dim light. To examine whether functional changes in rhodopsin are associated with shifts in selection intensity upon bat Rh1 sequences, we implemented selection analyses using codon-based likelihood clade models. While no shifts in selection were identified in response to diverse echolocation abilities of bats, we detected a significant increase in the intensity of evolutionary constraint accompanying the diversification of Chiroptera. Taken together, this suggests that substitutions that modulate the stability of the light-activated rhodopsin state were likely maintained through intensified constraint after bats diversified, being finely tuned in response to novel sensory specializations. Our study demonstrates the power of combining experimental and computational approaches for investigating functional mechanisms underlying the evolution of complex sensory adaptations.
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Just as a person plans for all of life's other major events, including weddings, relocations, and new jobs, one should also take steps to plan their funeral. However, death can be a difficult and uncomfortable topic to discuss, so bringing up this topic with a loved one requires care and consideration. To ensure they’re open to a conversation about funeral pre-planning, follow these steps.
How to Discuss Funeral Pre-Planning With a Loved One 1. Describe Your Own Plans
Ease into the conversation by bringing up your wishes for your own funeral. This way, you can more smoothly transition to asking your loved one about their plans. If they haven't considered funeral pre-planning, sharing your preferences may inspire them to start thinking about what they'd like. By introducing your wishes first, you're also inviting them into the conversation, rather than diving into the topic out of the blue.
2. Discuss Benefits
As your loved one gets more comfortable talking about pre-planning, inform them of the benefits of this option. Let them know that pre-planning takes a considerable emotional and financial burden off family members, and it's often seen as a final gift from them to those they care about. Also, stress that pre-planning will ensure their preferences are honored and that they can customize the service in any way they'd like, with favorite flowers, songs, readings, or other personal touches.
3. Take It Slow
This can be a big subject to digest all at once, so don't expect your loved one to commit by the end of the conversation. Keep the talk as light and casual as possible, and don't dwell on it if it's causing pain or distress. Let them know you'd like to keep the lines of communication open and that you're there if they want to continue sharing thoughts or ideas.
When you or a loved one is ready for funeral pre-planning, trust DiPonzio Funeral Home in Rochester, NY. Since 1931, they’ve been serving families throughout the Monroe County area, offering funeral and memorial services, burials, and cremations that are all customized to meet your exact needs and preferences. To schedule a consultation, call (585) 429-6700. To learn more about how they can help with pre-planning, visit their website.


Abstract
Myometrial contraction is a central feature of labor. Although a link between infection and preterm labor is widely accepted, surprisingly little is known about the mechanisms coupling infection-induced inflammation to myocyte contractile machinery. This study explores the myocyte response to pathogen-derived ligands in vitro. The pregnant human myometrial cell line PHM1-41 and primary cultured uterine myocytes responded to Toll-like receptor (TLR) ligands, including the bacterial wall component LPS, which at 100 ng/ml increased contraction of cells embedded within collagen gels over 72 h compared to PBS. LPS-treated myocytes secreted inflammatory mediators, including prostaglandin F2α, the cytokines TNF-α and IL-6, and a range of chemokines. The contractile response to LPS required TLR4 signaling and was independent of prostaglandin synthesis. Neutralizing TNF-α had no effect on LPS-mediated contraction; however, the Rho-associated protein kinase (ROCK) inhibitors Y-27632 (10 μM) and GSK-269962 (50 nM) both abrogated the contractile response. The finding of LPS-mediated contraction was supported by a 1.38 ± 0.072-fold (mean±SE) increase in myosin light-chain phosphorylation 48 h post-treatment, assessed by in-cell Western blot analysis. Together, these data suggest that, in addition to modulating the local inflammatory environment, pathogen-derived ligands may directly promote myometrial contractility via Rho/ROCK signaling, thus contributing to preterm labor-mediated preterm birth.
Keywords Amides/pharmacology Blotting, Western Cell Line Cells, Cultured Female Humans Imidazoles/pharmacology Infant, Newborn Lipopolysaccharides/pharmacology Muscle Cells/cytology Muscle Contraction/drug effects Oxadiazoles/pharmacology Pregnancy Pyridines/pharmacology Reverse Transcriptase Polymerase Chain Reaction Signal Transduction/drug effects Uterine Contraction/drug effects Uterus/cytology


In 2005, Brian and Kim Hutton were navigating uncharted territory with their 2½-year-old child. Assigned female at birth, she began stating that she was a boy. Confused and afraid, they weren’t able to share this information with family or close friends. The feelings of isolation were overwhelming. Kim searched the internet looking to connect with other families on this journey without success.
After years of struggling to connect and without local experienced professional resources, they met the Copeland family in 2009 who were raising a teenager who had lived a very similar experience. Kim immediately began urging Laurie to partner with her to form a support group so that no other family had to struggle in the same way.
In 2011, Kim secured a rental contract with the St. Louis Ethical Society to use their facility for monthly meetings. Laurie joined her effort, and they invited six families. With a simple, static website, the group began to grow. Families shared experienced medical and therapeutic resources as well as books and videos.
Realizing that credibility and legitimacy would be hard-won in 2012, Kim reached out to St. Louis Children’s Hospital, one of the top ten children’s hospitals in the United States, and requested meeting space within their facility. They granted her request, and in 2015 TransParent was awarded community partner status.
In 2013 TransParent invested in a website that allowed them to organize local professional resources like pediatricians, endocrinologists, therapists, and surgeons as well as transgender-friendly schools, news stories, and events. Another significant milestone occurred in 2014 when TransParent launched the Gender Independent Kids Club for children aged 5 to 12, also in the St. Louis Children’s Hospital complex. Recently the age limit was raised to 17.
Today TransParent is a 501c3 not-for-profit organization with sixteen chapters in nine states. Our mission is to normalize this naturally-occurring human experience and to empower children to live authentically.


The possessions you move into a rental house or apartment are precious to you. Still, property risks threaten here as in other homes, including the risk of theft. However, you can work with your landlord and on your own time to keep these theft risks low. A well-rounded
renters insurance policy can also help you protect yourself. Here's what to think about when making your rental home safer. Before Moving In
Renting a home or apartment is just as safe as owning one, in most cases. However, renters are not the owners of the homes they live in. They might not know all the safety resources they have available on the property.
As you prepare to sign your lease and move in, remember:
Request that your landlord change the locks throughout the property. Don't forget to change locks on closets, gates, windows cellars or crawl spaces. Only you and your landlord should be able to access the property.
Ask if the home contains a camera or alarm system. Reset the passwords on these devices upon moving in. Have the landlord teach you how to operate the systems.
If you notice potential hazards - like rusted hinges or misaligned door frames - then tell your landlord. If something doesn't work correctly, that increases the risk of a thief breaking in.
See if you have permission to install permanent safety devices. These might include doorbell cameras, motion-activated lights or key-code locks. These changes might require modifications to the home. Therefore, the landlord might not want the tenant to make the changes themselves.
When At Home
Everyone should feel safe at home. While the chances of a break-in, home invasion or theft is relatively low for most people, that doesn't mean you shouldn't take proper safety precautions when at home.
Always keep the doors locked. This is especially true in apartment complexes, where there might be a lot of foot traffic.
Only open ground-floor windows if they have safety screens installed. Never leave your doors open.
When not outside, keep gates, sheds and basement doors shut and locked.
Consider installing a portable security camera. Systems like Wyze© or Ring© smart cameras can send security footage to your smart phone. You can take these items with you when you move, and they require minimal installation.
For added safety, buy removable door & window jammers. You can also buy sensors that will alert you if someone opens a door or window.
Usually, your landlord must ask permission before entering your property or sending over a maintenance service. Therefore, ask that they tell you before someone comes to the property.
Don't keep your most-expensive items on clear view for passersby to see.
When Away
Whenever you leave home, either for an errand or
for a vacation, lock down the home. Some of the steps you might take include:
Bring inside outdoor furniture and equipment. Lock your gates and outbuildings.
Hide your valuables. You can choose to put items like jewelry, collectibles, identity-sensitive information and credit cards in a safe. However, conceal the safe as well, so that a potential thief cannot easily find it.
Set a timer on certain lights (or even your TV) so that they will turn on and off at certain hours.
Have someone you trust collect your mail and newspapers. If these items accumulate, thieves might take it as a sign that no one is home.
Keep your travel plans off social media.
Don't Forget To Buy Renters Insurance
You can't prevent every type of property theft, no matter how hard you try. That's why most renters buy renters insurance. Coverage can include
personal possessions coverage for your belongings.
Possessions insurance can help you recover belongings after a theft or other hazards. You can insure possessions for a certain value, then your renters policy can compensate you in case of theft. Keep in mind that limits and exclusions will exist on most renters policies.
Talk to your BluCanopy agent about whether you need to buy special endorsements or riders to expand your possessions coverage.


"This is stripped to a single raft, endlessly bobbing through the sea," says one player about the game. While one might expect this statement to be a set up for a bad review, it's actually the exact opposite. "And I've loved it!" finishes the Raft game fan. Raft begins by placing a single player and his or her friends (if multiplayer) at sea on a small plank of wood with nothing but a single hook made of plastic.
When players come to, all they see is an endless ocean, a frightening and daunting situation even for those with the sturdiest of sea legs. Avatars are parched and in dire need of sustenance. Players' objectives? To help their avatars survive.
Littering is a detriment to the environment as a whole, but it's safe to say that no other terrain suffers so much from humans' carelessness as the ocean. Raft creators who, at the time of creation, were three university students thrown together to work on a class project decided to use this fact to their advantage by placing a faceless character at sea with nothing but a piece of driftwood and a hook-shaped piece of garbage.
The goal? For drifters to catch whatever debris floats by and use it to build themselves a floating home worthy of survival. In this video game, it seems that to come across the Great Pacific Garbage Patch would be a lucky happenstance. Initially, floating patches of garbage contain simple objects avatars can use to create tools, which they can then use to capture food and water.
However, over time, as gamers grow stronger, the emphasis becomes less on satiating hunger and thirst and more on creating a self-sustaining environment at sea. It is then that players begin to notice more complex pieces of garbage coming their way.
Players are also encouraged to dive beneath the surface and scavenge trash-laden reefs for useful resources. If they happen to find tasty-looking sea life down in the depths, even better.
For players whose idea of fun does not involve floating on an endless horizon and digging for trash, the game offers a bit more excitement beneath the surface. While the raft floats, a man-eating shark circles below.
If players aren't vigilant, the shark can take a bite out of the hard-worked-for additions to the unanchored shelter. Occasionally, the shark will try to get a taste of any player who tries to swim a few yards to capture a piece of, particularly appealing debris or who wants to snag a bite to eat from the teaming reef below.
For some players, trying to survive in shark-infested waters is too stressful to do on a consistent basis. Yet, these players find solace in building extensive shelters from random odds and ends they happen to encounter in their drifting. The compromise? A creative mode.
In the early days of the game, Raft creators implemented a creative mode that simply allows competitors to build magnificent seafaring structures using their wits and debris.
Debris may include palm fronds, wood, plastic, rope, and metal. With these pieces of scrap, more ingenious Raft players develop tools and building materials they then use to create what are essentially houseboats, replete with beds, raised gardens, tables, porches, propellers, grills and other staples you might find at a land-based abode.
If players can get beyond the fact that they're drifting for no other apparent reason than to survive, they'll eventually spot something that looks a lot like land or a wrecked vessel. Are their eyes deceiving them? No, they're not.
Updates to the game brought with them small islands and abandoned vessels, which, if they can get to them, avatars are free to explore and loot for whatever items they need. These updates are particularly notable, as many derelict ships contain metal and pieces of waterlogged tech equipment that avatars can dry out to create electronic equipment that actually works. Think sonar, GPS and receivers that allow players to navigate rather than aimlessly drift.
The Large Island Update, a newer update, plays a key role in the new advanced cooking system. This system allows players to sustain avatars' hunger for much longer by eating meals that consist of ingredients found both at land and sea. The system includes 11 new recipes, which players can locate in crates hidden at rare locations.
The large islands contain a plethora of resources that the smaller islands, reefs and garbage patches don't, such as berries, mushrooms, cooking pots, stoves and more. Because of this, the creators don't make it easy for avatars to access these lands.
Before they can ground their vessels, players must battle the Screecher, a phoenix-like bird that can be found circling and protecting the new large islands. If the Screecher spots an avatar, it will attack onsite and bombard him or her with rocks. Players can defeat the Screecher by shooting it down with a bow and arrow (which, hopefully, the shark didn't nab) or during a spear battle.
If players think they can get around the Screecher by simply diving beneath the surface, they're wrong. A poisonous pufferfish roams around both the large islands and nearby reefs, protecting valuable resources. As with the Screecher, players must combat the pufferfish and prevail to access resources beyond.
Video gamers can only catch debris and avoid dangerous sea life for so long before growing bored. In response to demands for more, Raft game creators have implemented several new modes, including game mode, peaceful mode, an updated hard mode, third-person mode, and no-clip mode.
The game mode upgrade allows players to equip their rigs with armor and upgrade security so that, as they encounter other (sometimes volatile) players, they can focus more on protecting their home fronts than on pesky shark attacks.
For some, watching an avatar float on a raft sounds about as fun as watching paint dry. However, for those gamers willing to stick it out beyond the initial survival mode, Raft can be a stimulating game that provides the opportunity to exercise their creative juices and have a bit of virtual excitement.


In 1997, the Colorado Legislature established the Colorado Noxious Weed Management Fund to provide additional financial resources for on-the-ground noxious weed management. Organized private interests, conservation districts, municipalities, and counties have been eligible to apply for assistance provided that awarded funds are used to enhance weed management efforts within the State of Colorado.
Invasive Species Resources Displaying 1 to 6 of 6Search Help
Colorado Department of Agriculture.
Idaho State Department of Agriculture.
The primary purpose of the Idaho State Department of Agriculture's (ISDA's) noxious weed cost share grant program is to accelerate the attack on invasive weeds by supplementing local funds and resources, not replacing them. Cost sharing is also intended to provide additional incentives for local landowners, officials, and citizens to work collaboratively to develop a more comprehensive and effective noxious weed management program.
Minnesota Department of Natural Resources.
Minnesota Department of Agriculture.
Counties, municipalities, and weed management entities (including weed management areas) may apply for grants to address noxious weeds and invasive plants, with priority given to Palmer amaranth or other species on the Prohibited-Eradicate Noxious Weed List. This grant request is not to be confused with the Cooperative Weed Management Area (CWMA) grant program administered by the Minnesota Board of Water and Soil Resources (BWSR).
New York Department of Environmental Conservation.
The newly consolidated Invasive Species Grant Program combines previous opportunities, such as the Aquatic Invasive Species Spread Prevention and the Aquatic and Terrestrial Invasive Species Early Detection/Rapid Response grants, to create a single grant program designed to support projects that target both aquatic and terrestrial invasive species. In addition, the Invasive Species Grant program allows applications for two new categories: Lake Management Planning and Aquatic and Terrestrial Invasive Species Research.
California Department of Fish and Wildlife.
The Funding Opportunity for the U.S. Fish and Wildlife QZAP FY2020 has officially been posted. The total funding amount for projects is approximately $1,830,000.00, which is a significant increase from years past. This opportunity will be open for application through
October 18, 2020.


With a delinquency rate reaching the highest level since the Great Recession, auto loan debt has become serious business for lenders and the agencies that represent them. The factors leading to this decline include a record-high sum of newly originated auto loans ($584 billion in 2018), a record-high average price per vehicle ($37,577 in December…Details
Predictive modeling is used in many aspects of life today. For example, a fisherman can use predictive forecasts to determine the patterns of fish to find the best times and locations to get the most action. Similarly, in the world of collections, there are many fish in the sea with agencies challenged to handle massive…Details
The Association of Credit and Collection Professionals (ACA International) presents its annual conference July 14 – 16, 2019 at the Hilton San Diego Bayfront. The ACA International Convention & Expo 2019 features 35 educational sessions led by industry experts, an exposition hall showcasing innovative industry providers, and several opportunities to share best practices with peers…Details
Collecting on accounts receivable can bring in sizable amounts of revenue to clients, but third-party debt collection agencies should maintain a compliance management system (CMS) to provide legal compliance and other benefits. First, a CMS enables agencies to remain compliant with federal, state and local laws that protect consumer interests. The approach ensures that every…Details
Launching and maintaining best-in-class debt collection agencies requires a tremendous effort and an ongoing commitment to compliance, certification, data security, and collections technology. Recent articles in this blog have also discussed the importance of having highly qualified people in client relations and operations. Client relations teams are responsible for ensuring that clients are satisfied with…Details
Produced by insideARM, the 2019 First Party Collections Summit will focus on the unique challenges of first party collections, outsourcing collections management, and the consumer experience. The event is scheduled for June 17 – 19 at the Loews Vanderbilt Hotel in Nashville, Tenn. Over 350 first party partners are expected to attend, including 100-plus creditors and 100-plus collection agencies.Details


As of March 2020, everyone was asked to work from home where possible. This current shift in situation presents not only technological but also human factor challenges for information security. Organizations will have to tailor their awareness campaigns and training to target issues specific to working from home, confronting new security-based obstacles that their employees and clients might be facing.
In order to maintain both personal and organizational security, individuals must perceive information security risks realistically. However, people’s judgments regarding information security risks are influenced by a wide range of cognitive biases.
Cognitive biases are inherent characteristics of human nature and are present in everyday life. Biases refer to a predisposition to think a certain way, and affect our subsequent decisions, judgments and behaviors.
These biases often arise when we interpret risk and make decisions, particularly in times of uncertainty. There is a plethora of cognitive biases that have impact and consequence on the way we perceive information security risks. Here I will discuss two cognitive biases: optimism bias, and fatalistic thinking.
Optimism bias and information security
Optimism bias is sometimes used interchangeably with ‘overconfidence’, and refers to the phenomenon whereby individuals believe they are less likely than others to experience a negative event. This particular bias is said to transcend age, race and gender.
For example, experts have demonstrated the presence of the optimism bias in the beginning of the COVID-19 crisis. Research has revealed that, at least at the start of the outbreak, people underestimated their own risk of becoming ill or passing on the virus.
Optimism bias has further been demonstrated in information security risk perceptions. There are many reports that individuals perceive their risk to information security attacks, such as phishing, to be lower than others.
A recent poll of 2000 remote workers revealed that 77% said that they weren’t worried about security while working at home. This also extends to organizational contexts, where individuals believe their own organization to be at relatively lower risk to information security threats than other competitor organizations.
Fatalistic thinking and information security Fatalistic thinking refers to an outlook where individuals may believe they have no power to influence risks personally, as risks are controlled by external forces. In information security, this might mean believing there is nothing you can personally do to prevent a phishing attack, because you’re going to fall victim to a phishing attack anyway. Or believing that everything is ‘hackable’ and so there’s little point in protection efforts.
This feeling may augment with home working, as employees are distanced from usual organizational support.
Why is this important?As seemingly opposite as fatalistic thinking and optimism bias sound, they both stem from misinterpretations of risk and can lead to similar behavioral consequences. Individuals can both be optimistic about their own risk and believe that they have no power to reduce the risk anyway.
In addition to resulting in incorrect perceptions, optimism bias and fatalistic thinking can lead to increased vulnerability. If individuals are optimistically biased regarding information security threats, they may not take the precautionary measures to reduce risks. Similarly, if individuals believe risks are dictated solely by external forces, this will also reduce precautionary action. Both these biases can therefore actually increase risk.
How might we reduce the increased risk biases pose?Although these biases are heavily engrained, all is not lost. Instead of seeing the human as the ‘problem’, empowering employees to be part of the solution to information security issues might be a way forward.
It may help to take a ‘human as a solution’ approach to information security. In information security, humans are often viewed as the biggest issue. Therefore, efforts are made to exclude and control them. This removes the opportunity for individuals to contribute to their organization’s cybersecurity.
It is really no surprise individuals demonstrate perceptual biases if they are made to feel like the weakest link. Instead, organizations should learn from and involve employees in information security.
For example, organizations could ask employees the information security risks and problems they might be experiencing, or envisage experiencing, when working from home.
Firstly, this could reduce fatalistic thinking by demonstrating how employees can play an active role in reducing information security risks. Secondly, this could reduce optimism bias through awareness of security issues and by learning from a positive attitude. Hence, learning from employees could increase overall security.
Understanding biases may also help organizations tailor information and training. Training people to understand and cope with the risk should be at the forefront. Especially in the case of fatalistic thinking, organizations might endeavor to remove fear appeals as a method for communication and increasing feelings of morale and employees’ abilities to cope with threats.
Summary Overall, cognitive biases such as unrealistic optimism and fatalistic thinking are present in our everyday lives and can have negative impacts for risk mitigation. However, cognitive biases are normal mechanisms in human thinking and viewing the human as a solution, rather than a problem, could perhaps in itself mitigate any risks biases pose.


We like sharing natural insomnia remedies with our readers - so here's another one to start the week.
A recent study published in the Journal of Biological Chemistry found that two specific fragrances, vertacetal-coeur (which is derived from jasmine) and its chemical alternative PI24513, were just as powerful as sedatives such as benzodiazepines and barbiturates.
The study is being hailed as proof that there is a scientific basis for aromatherapy - however, we want to wait for future studies to be released before jumping on that bandwagon. If you're interested in learning more about this specific study, the United Kingdom's NHS website does a good job of offering a balanced analysis.
Of course, you shouldn't change your medication based on this study - but you might want to consider exploring aromatherapy as a natural insomnia remedy.
What have you got to lose?
Last updated: August 2, 2010


A large pharmaceutical company’s multiple manufacturing science and technology department teams operated from locations around the globe. Common goals of these teams required collaboration and information sharing to achieve results, but the groups were experiencing conflict, competition, lack of trust and breakdown in communication. Results were sub-par.
Continuum worked with an internal team to survey key members and gain a better understanding of situation dynamics.
The first priority was to improve work relationships between a specific U.S. team and one in Ireland. The Continuum Consultant designed a nine-month intervention that included multiple components:
Groups crafted an Ongoing Engagement Plan with shared agreements for working together, a process of accountability and agreed-upon methods for addressing potential conflict or lack of understanding before negative effects manifested.
In addition, the groups designed Action Plans, including timelines, that laid out group recommendations for improvements to present to management.
Upon reviewing program outcomes and the teams’ new working processes, their department leader stated that the increase in communication and trust were already evident. At this time, informal reviews show positive results have been maintained.


Operational principles for integrating IHBC’s research, guidance and advocacy for the production of Standards: A strategy for evidence-based conservation standards in the IHBC Drafts approved by IHBC’s Committees for Policy and for Education, Training and Standards, 2014 Context: Standards in practice and quality assurance
The need to value of standards in the discipline of conservation is acknowledged in the IHBC’s Corporate Plan 2010-15 (CP 10), Action 2.1:
‘Produce framework for development and adoption of standards appropriate to the IHBC as an interdisciplinary professional body.’
Standards are a fundamental tool in professional processes. Standards can play especially critical roles in conservation by:
generating efficiencies in the delivery of conservation, by representing agreed and consolidated principles of practice, and helping in the scrutiny of that practice within quality assurance processes.
This note explains how the IHBC can integrate its core activities and unique resources to achieve its corporate objectives through a focus on evidence-based conservation standards.
Issue: Challenges for interdisciplinary standards
Conservation is inherently an interdisciplinary activity (ICOMOS 1993). Barriers to that interdisciplinary activity will threaten successful conservation. Unless standards reinforce practice inclusively across the relevant disciplines they may be seen as obstructive to the delivery of outcomes rather than as conclusive statements on how to secure those outcomes.
To date, conservation standards usually have been based on a description of practice, often based on judgement within a particular discipline. If standards remain no more than the description of a judgement within one or more select disciplines, they are unlikely to be adopted as the definitive statement on the effective delivery of sustainable conservation outcomes.
However, if conservation standards are based on sound evidence, they will offer a secure foundation for their adoption by all parties involved in the delivery of conservation, regardless of practice or discipline.
IHBC’s evidence-based standards for conservation professionals
Effective conservation standards should be developed out of research-based evidence supported by practice-based guidance. Sound evidence must be developed within a credible evidence-based research process. However that research can underpin practice only where proven in operation. Testing of evidence-based practice standards takes place through the development and operation of guidance for practitioners.
Consequently, the IHBC’s development of standards will begin with developing research that generates evidence to shape practice through guidance that, when tested, underpin standards.
In summary, the IHBC will develop its standards as follows, by:
Promoting research, gathering data to establish Evidence Developing Evidence into Guidance that shapes Practice Testing Guidance, in Practice, to underpin Standards IHBC priorities for production of standards – Strategic: Advocacy
The IHBC is uniquely placed to integrate conservation research, guidance and standards to deliver advocacy supporting conservation outcomes. The IHBC’s priorities in planning for research, guidance and standards, consequently, are shaped by their potential to deliver advocacy.
Principles in identifying and interpreting evidence
As conservation is an interdisciplinary process, the nature and scope of the practice of conservation is necessarily diverse.
To ensure that the IHBC’s strategy for developing standards is fit-for-purpose, appropriate interpretation strategies must be identified. Specific approaches are justified for use by the IHBC where they sit within the recognised framework of evidence-based conclusions as follows:
Evidence includes empirical, for example based on practice Methodology includes heuristic, for example using aggregated evidence Logic includes inductive, for example though indicative conclusions. Summary: communicating & promoting evidence-based standards
Successful advocacy depends on the promotion of credible standards based on an accessible evidence base that informs practical guidance.
The IHBC has a critical communications role in delivering that advocacy by promoting all aspects of evidence-based standards across its networks:
Research Papers: Present evidence Guidance Notes: Inform practice Standards: Underpin outcomes Collectively: Generate Advocacy IHBC, 16 October 2014 PDF download of above document


New York — WattBuy, an online electricity marketplace that empowers consumers to make smarter decisions about their electricity costs by allowing them to browse and select plans in their area, announced it has raised $3.25 million in its Series A round of funding led by Evergy Ventures. Additional investors include Updater, Avesta Fund, Yoav Lurie, John Sherman, and Bill Gatreaux.
Existing investors also participating in this round include Fort Ventures, Techstars Ventures and Powerhouse Ventures.
Each investor brings a significant track record in supporting innovative companies that create solutions to decarbonize and democratize the energy value chain.
“We are thrilled to have leading energy technology investors recognize WattBuy’s contributions to energy innovation,” said Naman Trivedi, CEO and co-founder of WattBuy. “These funds enable us to expand our turnkey API offering within market-leading real estate platforms like Updater as well as personal finance companies and energy services businesses. We’re enabling enterprises to launch their own renewable electricity marketplaces that can increase value to their existing customers.”
WattBuy’s Series A funding round follows the successful launch of the first-ever calculator to estimate the electricity cost and carbon footprint impact for nearly every home in the United States.
This calculator incorporates several open and proprietary data sources to build a machine learning model that takes location, building characteristics, and weather data as inputs, and returns an hourly electricity usage prediction. WattBuy will continue to improve this machine learning model with the funding from this round.
“WattBuy is providing an important service to consumers by helping them find the best electricity plan for them, including factors such as price and sustainability,” said Dennis Odell, vice president at Evergy Ventures. “We are thrilled to be partnering with WattBuy, a company that shares our passion for clean, safe, reliable energy solutions, as it expands its offering to enterprises.”
“Moving signals an important inflection point for electricity – the start and stop of service,” said David Greenberg, founder and CEO of Updater. “WattBuy’s transparent full-market views and innovative purchase experience will allow Updater movers nationwide to shop for and turn on electricity more efficiently than ever before. We’re thrilled to partner with WattBuy on such a compelling use case.”
“Consumers have long desired greater choice in their energy decisions,” said Yoav Lurie, founder and CEO of Simple Energy, which merged with Tendril to form Uplight. “WattBuy really shines for its ability to reach consumers when they are making energy decisions. I’m excited to see them partnering with enterprises to scale their reach across the U.S. and enhance the customer experience at this critical time in the marketplace.”
Over the past two decades, several state governments have deregulated their electricity markets, allowing residents to choose who provides their electricity. Today, over 140 million Americans in 14 states can use WattBuy to choose among over 100 electricity providers and approximately 5,000 plans to find one that matches their preferences. On average, these residents could save $360 per year by selecting a less expensive electricity provider.
Earlier this year, WattBuy initiated a Schmidt Futures-funded project in partnership with the U.S. Department of Energy’s National Renewable Energy Laboratory (NREL) to create the nation’s first complete, up-to-date database of electricity rates.
Since its founding in 2017, WattBuy has raised a total of $5 million in venture funding. The company closed its $1.5 million seed round in July 2019.


Across the United States, many voters have already cast their ballots for the 2018 midterms during their state's early voting period. In one state, Georgia, early voting turnout has far surpassed its previously record-breaking 2014 early voting rate. This strong early voting turnout brings further attention to the state, which is already being closely watched because of its potentially history-making gubernatorial race.
On Monday, Georgia's Secretary of State, Brian Kemp (who is also the state's Republican gubernatorial candidate) revealed in a statement that Georgians cast 2,071,830 ballots during the state's early voting period, which ended on Nov. 2. This number dwarfs the state's previous record for midterm early voting turnout, which consisted of 945,507 voters casting early voting ballots in 2014.
In the same statement, Kemp expressed pride that turnout had been so strong during Georgia's early voting period. As the Secretary of State described:
In Georgia, it is easy to vote and hard to cheat, and I am incredibly proud of this new record showing strong voter engagement leading up to tomorrow’s election. This milestone is a testament to the hard work of thousands of election officials all across Georgia who are dedicated to secure, accessible, and fair elections for all.
Georgia is home to a gubernatorial race that is being closely followed by the state's residents and beyond. In the race, Kemp is facing Democrat Stacey Abrams. The latter could become the first-ever African American woman governor in the United States if she secures victory on Tuesday.
In addition to its possibly history-making race for governor, Georgia has also received a lot of attention because of its voter purge last year, which was spearheaded by Secretary of State Kemp. As American Public Media reported, in 2017, over 100,000 voters were removed from the voter registration rolls for failing to make contact with election officials or vote within a designated period of time. The outlet noted that many of these voters were not aware that they had been removed from the rolls, meaning they could think they are eligible to vote on Nov. 6, but will instead be turned away at the polls.
Georgia is not the only place where early voting has been exceedingly high. As
Politico reported on Nov. 5, across the United States, a total of 36 million voters have cast early voting ballots. This number far outpaces the nationwide early voting turnout for 2014's midterms, in which 27.2 million people cast their ballots ahead of Election Day. In three states, Arizona, Nevada, and Texas, early voting rates are higher than each state's entire turnout for the 2014 midterms.
As
Politico noted, it is not yet certain what these record-breaking early voting numbers mean for Election Day turnout or for the prospect of Democratic versus Republican victories on Tuesday. However, generally, experts seem to agree that this election is quite unique in terms of voter turnout. "This is not a normal election,” Michael McDonald, a professor at the University of Florida who tracks voter turnout, told Politico. “The best guess is that we’re looking at some sort of hybrid midterm/presidential election [in regard to turnout]."
Overall, the 2018 midterms appear to already be making history as a result of strong early voting turnout, in Georgia and beyond. It remains to be seen how the rest of the midterms' story will unfold as voters around the United States head to the polls on Tuesday.


Hooding of the upper eyelids is a common concern amongst my Houston upper eyelid surgery patients. As we age, we lose elasticity and collagen in our skin. This is most evident around our eyelids, the thinnest skin in our body. Hooding of the upper eyelids may begin with patients in their 30’s depending on their skin type. Hooding of the eyelids refers to excess skin overhang on the lateral or outside portion of the upper eyelid. This may give the appearance of tired eyes, or heavy eyes. Hooding of the upper eyelids may also make placement of eye shadow and mascara difficult.
In addition to the aesthetic concerns that may occur with upper eyelid hooding, some patients complain of peripheral visual loss due to this issue. Although Dr. Funk does not take insurance for upper eyelid surgery, upper blepharoplasty should improve vision if you have significant hooding of the upper eyelids.
Treatment for upper eyelid hooding can be non-surgical and surgical. Botox or Dysport injections can weaken the brow depressing muscles and lead to a slight lift of the tail of the brow helping with hooding. This is not as significant as a surgical brow lift, but can lift the brow by 1-2mm.
If the issue with hooding of the upper eyelid skin is due to heavy brow skin, a temporal brow lift is a surgical option for this issue. With a temporal brow lift, an incision is made behind the hairline in the temple and the skin is elevated to the brow. The muscle above the brow is suspended to the firm fascia and a small amount of excess skin is excised.
With most patients, upper eyelid hooding is simply due to excess upper eyelid skin laterally. An upper blepharoplasty or upper eyelid surgery can address this issue. Excision of this excess hooded skin is performed and the scar is hidden nicely in the eyelid crease and crow’s feet. This procedure can be performed under local anesthesia or slight sedation. Recovery is 5-7 days.
For further information regarding upper eyelid hooding in Houston, contact Dr. Funk’s office.


Radislav Nakov* and Tsvetelina Velikova Pages 260 - 269 ( 10 )
Among the gut microbiota’s newly explored roles in human biology is the ability to modify the chemical structures of foreign compounds (xenobiotics). A growing body of evidence has now provided sufficient acumen on the role of the gut microbiota on xenobiotic metabolism, which could have an intense impact on the therapy for various diseases in the future. Gut microbial xenobiotic metabolites have altered bioavailability, bioactivity and toxicity and can intervene with the actions of human xenobiotic-metabolizing enzymes to affect the destiny of other ingested molecules. These modifications are diverse and could lead to physiologically important consequences.
In the current manuscript we aim to review the data currently available on how the gut microbiota directly modifies drugs, dietary compounds, chemicals, pollutants, pesticides and herbal supplements.
Xenobiotics, gut microbiota, drug metabolism, pollutants, bioavailability, bioactivity, toxicity.
Clinic of Gastroenterology, Tsaritsa Yoanna University Hospital, Medical University of Sofia, Sofia, Clinical Immunology, Lozenetz University Hospital, Sofia


Please note that all resources below are written, filmed or nominated by PwPs, these are for your information only and are not offered as medical advice. Slowness and Stiffness
Slowness of movement (bradykinesia) is a separate symptom to stiffness and rigidity; but these symptoms can impact each other.
A recent survey highlighted some common features of
slowness of movement and stiffness and rigidity: Slowness of movement Poor mobility Legs not moving Reduced reaction time Standing still Stiffness and rigidity Muscle tension/tightness Reduced flexibility Mask-like face (often noticed as a reduction in smiling) Dystonia (painful muscle spasms sometimes described as cramping, curling or seizing up) Sofa to Standing Foot dystonia


AAKG Revolution is raw, unflavored arginine alpha-ketoglutarate. L-Arginine is a conditionally essential amino acid and a chemical precursor to nitric oxide, a blood vessel widening (vasodilating) agent.
Benefits
Improvements in blood flow leading to a bigger “pump.” Increases muscle mass Reduces body fat Stimulates muscle protein synthesis Supports cardiovascular health
Direction of use
recommended serving size 1-2g, twice a day. One serving in the morning and one serving 45 minutes before training for best results. Arginine Alpha-Ketoglutarate (AAKG) can either be taken on its own or added to your protein shake.


Like many design firms, UK based Frip Design and Research is exploring the innovations made possible by 3D printing technology. Their latest endeavor is developing 3D printed prosthetics, which could significantly reduce the normal time and cost necessary to supply patients in need. While the design stage is relatively complex, the entire process including printing takes less than 2 days – significantly less time than the average 10 week wait that many patients have to endure.
In an interview with Dezeen, Tom Fripp of
The prosthesis is then printed with a Z Corp 3D color printer using compatible starches and medical grade silicone, which is colored to match the patient’s skin tone. The prosthesis can then be snapped into place and sealed with a medical adhesive.
Even though the prosthesis can be produced months before a regular handmade one would be ready, the cost of the pieces is only slightly lower than normal. This is due to the extensive mapping and design necessary for each individual face. After the initial design file is made though, replicas and replacements are significantly cheaper. Prosthetic eyes are the exception; since the size and shape of eyes are typically constant, the same pattern can be used repeatedly to produce prosthetic eyes at less than 10% of the typical cost.
While the prostheses have been fitted to patients and the technology is ready, Fripp Design is still involved in the long process of medical accreditation. Frip estimates that the prosthetics could be available to the public within a year.


The optical fiber technologies have considerably improved in the current times. It's in fact among the latest technologies that are used in communicating.
The excellence of this technology was instrumental in the inventions in the field of communicating. You can even take help from the
Professional Detectors Expert for the optical fiber systems.
The use of these technologies in telecommunication systems, information systems, and cable television transmission has contributed to the efficacy factor of these regions.
The scientific program and technology of optical strands is the simple idea behind these systems.
The high speed of information transmission has greatly led to rapid and efficient communication in a variety of fields.
The light signals are composed within the crux of the thread and making the machine more efficient compared to other systems.
The information signs often diminish in different systems. The greater spend compared to conventional techniques is also one of the factors for its use from the long-distance data transmission.
Several distinct kinds of optical cables are utilized in the communication situation today. A fundamental optical cable includes two layers.
The middle component of this strand is referred to as the center. The signs in the kind of light beams traveling through the crux of the strand.
The protective shield beyond the heart is referred to as cladding. The major purpose is protecting the heart from intense interference.
Cladding also functions as the inner reflective border that permits complete internal reflection. It's also the crucial factor as it empowers the signals to journey towards the ideal path towards destination.


Abstract
The plasma concentration of atrial natriuretic polypeptide (ANP) was measured in nine patients with essential hypertension during two grades of exercise tests performed in the supine position on a bicycle ergometer. The plasma ANP concentration significantly increased from 97.0 ± 19.2 pg/ml to 107.6 ± 23.7 pg/ml (p < 0.05) during low-grade exercise (50% of the maximal heart rate) and from 96.2 ± 16.5 pg to 192.8 ± 30.7 pg/ml (p < 0.01) during high-grade exercise (75% of the maximal heart rate). During high-grade exercise plasma epinephrine and norepinephrine concentrations showed significant increases. The plasma ANP concentration was significantly correlated with systolic blood pressure (r = 0.51; p < 0.05). Patients with essential hypertension showed greater absolute increases in the plasma ANP concentration and systolic blood pressure during exercise compared to normotensive subjects. These results suggest that exercise stimulates secretion of ANP in response to its intensity in patients with essential hypertension and that a greater rise in atrial pressure, resulting from a greater elevation of systolic blood pressure, may be involved in the exaggerated secretion of ANP in patients with essential hypertension.
ASJC Scopus subject areas Cardiology and Cardiovascular Medicine


Abstract
Background Functional and structural damages in sinusoidal endothelial cells (SECs) have a crucial role during hepatic ischemia-reperfusion injury (IRI). In regulating endothelial function, sphingosine-1-phosphate receptor 1 (S1PR1), which is a G protein–coupled receptor, has an important role. The present study aimed to clarify whether SEW2871, a selective S1PR1 agonist, can attenuate hepatic damage caused by hepatic IRI, focusing on SEC functions. Methods In vivo, using a 60-min partial-warm IRI model, mice were treated with SEW2871 or without it (with vehicle). In vitro, isolated SECs pretreated with SEW2871 or without it (with vehicle) were incubated with hydrogen peroxide. Results Compared with the IRI + vehicle group, SEW2871 administration significantly improved serum transaminase levels and liver damage, attenuated infiltration of Ly-6G and mouse macrophage antigen-1-positive cells, suppressed the expression of vascular cell adhesion molecule-1 and proinflammatory cytokines in the liver, and enhanced the expressions of endothelial nitric oxide synthase (eNOS) and vascular endothelial (VE) cadherin in the liver (eNOS/β-actin [median]: 0.24 versus 0.53, P = 0.008; VE-cadherin/β-actin [median]: 0.21 versus 0.94, P = 0.008). In vitro, compared with the vehicle group, pretreatment of SECs with SEW2871 significantly increased the expressions of eNOS and VE-cadherin (eNOS/β-actin [median]: 0.22 versus 0.29, P = 0.008; VE-cadherin/β-actin [median]: 0.38 versus 0.67, P = 0.008). As results of investigation of prosurvival signals, SEW2871 significantly increased Akt phosphorylation in SECs and decreased lactate dehydrogenase levels in supernatants of SECs. Conclusions These results indicate that S1PR1 agonist induces attenuation of hepatic IRI, which might be provided by preventing SEC damage. S1PR1 may be a therapeutic target for the prevention of early sinusoidal injury after hepatic IRI.
All Science Journal Classification (ASJC) codes Surgery


Is there really a difference between observational science, which examines facts in the present, and historical science, which draws conclusions about the past? Not everyone thinks so. The answer has major implications for critical thinking, so let’s unpack the definitions for these two types of science and investigate whether the distinction between them is valid.
Cast


For many, college is their first experience attempting to navigate the real world and manage responsibilities, including maintaining a balanced budget. Why would you suggest hindering their development toward full-fledged adulthood like this? I’d venture to guess that ALL college students are low income. I know I was, but I still managed to eat well. Everyday, every moment, we’re faced with the challenge of making good decisions, and with every single one we have to be able to say no to one thing or another. That’s life, and no socialist model will save anyone from that reality. Student loans and feeding students are not the problem we need to address with respect to higher education in our country. The problem is more aptly defined in the skyrocketing costs of education in part driven by seductive amenities and the sensationalist sports culture we promote. Higher education steers further and further away from EDUCATION with every new class of students. We need to realign ourselves and our culture with the heart of education, working with colleges to ensure the integrity of education, reduce costs, and ensure appropriate levels of financial aide provided through their endowments. We need to lessen the need for loans and federal aide by addressing these issues at their source.


In this installment of a 13-part series of monthly articles, The Combustion Institute recognizes the 2019 Distinguished Papers selected from among the scientific papers presented during the 37th International Symposium on Combustion. Congratulations to C. Paul, D.C. Haworth, and M.F. Modest for winning the DPA in the Internal Combustion Engines colloquium.
Their authoritative paper,
A simplified CFD model for spectral radiative heat transfer in high-pressure hydrogen–air combustion systems , has significantly improved the ability to accurately calculate radiative reabsorption at a fraction of the computational costs normally required. Using a simplified stepwise-gray model for spectral radiative heat transfer in engines, they provide a less computationally intensive model that captures the essential redistribution of in-cylinder energy and radiative heat loss and that can be used in routine engineering CFD for engine development and design.
The researchers envisioned a simplified radiation model that could address the computational cost associated with solving the complex spectral effects of radiative transfer equation. The team created a P1/Stepwise-Gray radiation model and compared it with a simpler, P1/Gray, model and more detailed, PMC/LBL and P1/FSK radiation models. The study demonstrated that the P1/Stepwise-Gray model can compute radiative reabsorption for different engine-relevant operating conditions with less than 10% error, while the error for a P1/Gray model is as high as 60% compared to the detailed radiation models. The computational cost of the P1/Stepwise-Gray model is approximately 15 times lower than that of P1/FSK and 30 times lower than that of PMC/LBL.
While the focus of the team’s study was diesel engines, they believe the proposed radiation model could be broadly applicable to other high-pressure hydrocarbon-air combustion systems, such as gas turbines and rocket engines.
The work supporting this paper began approximately in March of 2017 and concluded in November of 2017. The research was conducted mainly in the Mechanical Engineering Department of the Pennsylvania State University, with collaborative support from Professor M.F. Modest of University of California Merced. Their work was supported by the U.S. Department of Energy (DOE), Office of Energy Efficiency and Renewable Energy (EERE), the Department of Defense, Tank and Automotive Research, Development, and Engineering Center (TARDEC), and U.S. National Science Foundation (NSF).
The team believes their findings will help the scientific community to accurately model the radiative heat transfer of a high-pressure hydrocarbon-air combustion system at an affordable computational cost.
Over 1,600 papers were submitted to the 37th Symposium in 13 combustion science colloquia. Those papers were categorized by teams of colloquium coordinators and co-chairs, and then distributed to approximately 1,000 scientific reviewers. One paper in each discipline was awarded the recognition of Distinguished Paper.
The 13 Distinguished Papers undergo committee review for consideration to receive the Silver Combustion Medal that will be awarded during the 38th International Symposium in Adelaide, Australia. A paper selected for this honor exemplifies quality, achievement, and significance to advance a field of combustion science. Distinguished papers are selected biennially from among the scientific papers presented during the International Symposium on Combustion and accepted for publication in the Proceedings of The Combustion Institute.


The complete SPEC kit is Fee-Based (Order Form).
From a SPEC Kit #326 Summary:
The Association of Research Libraries (ARL) has published
Digital Humanities, SPEC Kit 326, which provides a snapshot of research library experiences with digital scholarship centers or services that support the humanities (e.g., history, art, music, film, literature, philosophy, religion, etc.) and the benefits and challenges of hosting them. The survey asked ARL libraries about the organization of these services, how they are staffed and funded, what services they offer and to whom, what technical infrastructure is provided, whether the library manages or archives the digital resources produced, and how services are assessed, among other questions.
This survey revealed that library-based support for the digital humanities is offered predominantly on an ad hoc basis. However, as demand for services supporting the digital humanities has grown, libraries have begun to re-evaluate their provisional service and staffing models. Many respondents expressed a desire to implement practices, policies, and procedures that would allow them to cope with increases in demand for services.
This SPEC Kit includes documentation from respondents that describes the mission or purpose of digital humanities centers, the services offered, policies and procedures, examples of digital projects, fellowship and grant opportunities, promotional materials, and repositories for digital projects.
The executive summary and table of contents are available online, free (14 pages; PDF).


Self-defense in a tort is used as a justified legal defense to win a personal injury lawsuit.
What Is Self-Defense?
In criminal and tort law, it refers to a defendant’s right to use physical force to defend oneself from bodily harm. It is commonly referred to as a justifiable defense.
How Much Physical Force Can Be Used?
The amount of force used must be reasonable and match the plaintiff’s force. If the plaintiff threw a punch at the defendant, the defendant could block the plaintiff’s punch with a punch of their own.
What Is the Difference between Self-Defense and Excessive Force?
Excessive force is physical force that goes too far. In other words, it does not match the level of force the plaintiff threatened to use or actually used. An example of excessive force occurs when a plaintiff punches the defendant. The defendant then shoots the plaintiff in the stomach using a gun.
What Is Deadly Force Involving Self-Defense?
Deadly force involves using physical force that can or does cause death or serious bodily injury. It can only be used when a defendant is threatened with deadly force without any reasonable way to escape.
When Can a Defendant Claim Self-Defense?
A defendant can claim this defense when sued for battery or assault. It is also used in false imprisonment cases where a defendant was bound to a certain area without their consent by the plaintiff.
Could a Plaintiff Win a Tort Claim If Self-Defense Is Used?
Yes, it is possible. Remember, every case is different. A defendant who attacked the plaintiff, exact revenge, or went beyond the level of the threat could lose the case. Also, a defendant who successfully defends themselves, but continues to use force against the plaintiff may also lose their case.
For example, a plaintiff punched the defendant. The defendant then punched the plaintiff back before they could land another punch. This is adequate self-defense. However, if the defendant continues punching the plaintiff without any continued threat from the plaintiff, self-defense is no longer a viable defense.
Should I Talk to an Attorney about Self-Defense?
If you are facing a tort action, you should talk to personal injury attorney about the defenses available to you.


Rapid delivery, with no compromise on quality
Modular buildings equal the durability and quality of permanent buildings, being built to the latest building regulations and planning requirements. The key advantage of modular construction is the significant time saving.
For example, a completely new modular office building will typically be ready for occupation up to 50% faster than a traditionally constructed building, or a refurbised option can be ready up to 70% faster.


In Australia, over 6,000 adults younger than 65 have been inappropriately placed in nursing homes designed to accommodate older adults. The primary aim of this review was to map the literature on the experiences and outcomes of young people with disability who are placed in aged care.
This article was published Open Access, and is redistributed by Summer Foundation under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License (CC BY-NC-ND).
Published online: 08 Sep 2020


New Jersey woman suffers brain damage following surgery
June 14, 2012
We hear a significant amount of talk in the news concerning medical malpractice awards. Yet what is often forgotten in such discussions is how significant injuries resulting from medical malpractice can be.
Recently, a 69-year old New Jersey woman may have suffered a brain injury due to a botched surgical procedure. In what has been described as a “comedy of errors,” an improper incision may have led to internal bleeding and an infection that remained untreated for a number of weeks. Finally, when surgery was performed to address the infection, too much damage had already occurred.
The woman had remained hospitalized for her condition for a significant amount of time. She also has since been treated for a number of bed sores. The woman is now confined to a nursing home where she continues to suffer from a significant brain injury.
When patients require surgery, there is always the danger of brain injury if certain safety precautions are not taken. There is always the risk that anesthesia will not be properly administered, or that not enough action is taken to revive a patient that has undergone anesthesia. In the case of the woman mentioned above, there is also the danger of surgical error that can eventually lead to brain trauma.
Experienced attorneys in the medical malpractice and personal injury areas can address clients concerns if they suspect that someone was injured due to a medical error. Sadly, many such brain injuries that occur due to such a mistake can be catastrophic.
This is not the first time that the hospital has been blamed for a medical error. Recently, an organ donor died while planning on donating a kidney to her brother.
If hospitals are not held accountable for such injuries, the likelihood of such errors will continue.
Source: Fox News, “Family sues scandal-hit New York hospital after woman suffers brain damage,” June 12, 2012


Social Media
Strengthen Reputation
Enforce Loyalty Loop
Grow Audience
A Forbes study revealed that 78% of consumers say their purchases are impacted by companies’ social media posts. A strong social media profile is an effective tool for any sales strategy because of the ability to meet people at many stages of the consumer decision journey (CDJ). Social media allows your brand to be at the front of potential consumers’ minds, when considering a service or product. Having a strong profile, with positive reviews, a strong following, and evidence of credibility within the industry, makes you a viable purchasing option. With digital media having such a strong impact, the journey does not end with a purchase. Instead, you want to move them into the loyalty loop, where they will not only continue to patron your brand, but will advocate it to everyone they know. Our social media strategies will create moments for others to advocate organically and put your brand in ongoing dialogue, keeping your brand visible.