Giant Microbes Original Measles Morbillivirus
FACTS: Measles, sometimes known as rubeola, is a well-known, highly contagious virus. Although its telltale symptoms are body-covering red spots often accompanied by a mild fever, it is in fact a respiratory disease that can lead to life-threatening conditions such as pneumonia and encephalitis (or brain swelling and degeneration). And indeed, in countries where malnutrition and poor health are prevalent, measles infections can be fatal.
The good news is that in 1963 scientists synthesized a vaccine from a live rubeola virus, and nearly all children in the developed world are now inoculated against measles, typically along with mumps and rubella when they receive their MMR shot. (A vaccine against varicella, the virus which causes chickenpox, is now often included in the shot, making it the MMRV.)
However, in developing nations that lack widespread vaccination programs, measles remains a significant health threat. Indeed, the World Health Organization calls measles one of the leading causes of vaccine-preventable childhood death.
Fortunately, international efforts to vaccinate against measles are having a significant impact upon the incidence of measles worldwide. As global vaccination campaigns continue, additional lives will be saved.
(Measles is nicht to be confused with German measles vich is caused by a completely different wirus.)


Applications are being invited for arts, museums and libraries projects that engage people in England with arts and culture.
After suspending the National Lottery Project Grants programme in March 2020 due to the coronavirus/COVID-19 crisis, Arts Council England is re-opening the programme for applications today, aiming to support individuals and organisations to get activities up and running again.
Applications are accepted for grants of between £1,000 and £100,000. The total amount of funding available between July 2020 and April 2021 is £59.8 million.
The grants can support a broad range of activities, ranging from projects that directly create and deliver creative and cultural activity and content for audiences, visitors and digital users, to those that have a longer term impact on strengthening the sector, such as organisational development, research and development and sector support.
Due to the impact that the coronavirus pandemic has had on the arts sector, the Arts Council is particularly keen to support:
Most of the criteria of the programme have remained the same as they were before it was suspended but the Arts Council has removed the requirement for a minimum 10% match funding until further notice, taking into account that artists and organisations are struggling to secure any additional funding under the present circumstances. Additionally, some changes were made which were already due to launch before the programme was suspended. Most notably, public libraries can now apply for grants to deliver activities addressing any one of the four Universal Library Offers (Creativity and Culture; Reading; Information and Digital; Health and Wellbeing).
Applications will be accepted on an ongoing basis from 22 July 2020 onwards.


Individuals who face mounting debts such as student loans may qualify to have these debts discharged after filing for bankruptcy. Being absolved of these financial obligations can occur only if the debtor proves that the debt will result in undue hardship for both him and his dependents. As any bankruptcy attorney will attest, proving your undue hardship rests upon three key factors:
1. A debtor cannot maintain a minimal standard of living based on his current income and expenses. If a judge decides to release you from your debt, you must first prove that your attempt to repay it will result in a severe negative impact to your quality of life. Only if evidence that supports this claim is provided will the court then consider the remaining undue hardship qualifications. 2. Current circumstances indicate that for the duration of the repayment period, or a significant portion of it, the debtor will continue to experience hardship if forced to maintain his debt. Many bankruptcy lawyers consider this to be the hardest factor to prove. Basically, a judge must be persuaded that, over the duration of your repayment period, you will not experience a significant change in lifestyle or income level that will allow you to more easily resolve your debt. However, if you can successfully argue this point, you have only one more obstacle to overcome in proving your undue hardship. 3. The debtor has made a good-faith effort to repay his debt. Have you tried to pay off your debt? Can you show the judge proof of your past efforts to maintain and reduce your debt? If so, you have effectively made your case for undue hardship. At this point, should the judge decide in your favor, you would be released from all further responsibilities in paying off your debt.
Do you qualify for undue hardship? The bankruptcy law firm of Cutler & Associates, Ltd. can help you to determine whether you are eligible for having some or all of your debt discharged after declaring bankruptcy.


Dollar reached a 14-year high
Following the US election results and Donald Trump’s win, the market is speculative about the US economic growth outlook as well as the timing of a US interest rate hike, considering Trump’s protectionist policies.
Trump has announced that he will spend $1 trillion on infrastructure construction. This spending, along with a reduction in taxes, is likely to give trade restrictions as well as the economy a significant boost, which could fuel inflation. Trump’s inflationary policies, combined with the already hawkish Federal Reserve, points to higher interest rates in the future. These sentiments have led to the upward trajectory of the US dollar (UUP), which reached a 14-year high on November 16, 2016.
Tech sector’s vulnerability to US dollar fluctuations
The above chart shows that IBM generates more than half of its revenue from outside the United States. Apart from IBM, Oracle (ORCL), Symantec (SYMC), and Microsoft (MSFT) are some of the leading technology players that derive a majority of their revenues from regions outside the United States. These regions include the EMEA (Europe, the Middle East, and Africa) and the Asia-Pacific. As a result, their top lines are significantly impacted by the appreciating US dollar.
Apart from significant revenue generation, cash parked overseas adds to these companies’ vulnerabilities to currency fluctuations.
Later in this series, we’ll discuss the growing cash reserves in the tech sector.


(1 Samuel 2:30 ESV) “… for those who honor me I will honor …” If you have ever watched the movie “Chariots of Fire”, you may remember the scene where Eric Liddell, a Scottish runner for Great Britain, is about to run the 400 meter race in the 1924 Olympics in Paris. Most people are doubtful of Liddell’s ability to when this race. In the film, just before the race begins, Jackson Scholz – an American runner, hands Liddell a note; “It says in the good Book, ‘He that honors me, I will honor.’ Good luck.” (Actually, the note was sent by Eric Liddell’s teammates, but this is movie history.) As real history records, Eric Liddell went on to win the race. Let us consider what God is saying in the phrase, “for those who honor me I will honor.” God is justly jealous of His honor. He would not be God if He was to part with one molecule of His attributes. Thus, to honor God is to trust Him to be all that He says He is. We must totally trust in God’s divinity and His revealed Word. Doubt dishonors God and His Word. As Christians, we must beware of those who hold low views of biblical inspiration, as well as those who tamper with the meaning of Scripture. Christians should stand in awe of God’s divinity and bow unquestioningly to His Authority and Word as found in the Bible. As we honor God, He honors us by making His Word a light in the darkness of difficult times. (Psalm 119:105) Honor God’s Word and it will guide you in life, support you in death, and take you to heaven. Honor God’s Word and He will honor you by making that Word the joy of your soul. Paul writes, “Let the word of Christ dwell in you richly, teaching and admonishing one another in all wisdom, singing psalms and hymns and spiritual songs, with thankfulness in your hearts to God.” (Colossians 3:16 ESV) Christians are to pursue a God-honoring faith that rests in Him with a childlike and unquestioning confidence. Faith that honors God is a faith that relies on His power to complete all that He has pledged in His covenant and Word to perform. We honor Him by our unhesitating trust in His power, faithfulness, and love. The Scriptures teach us that, “You keep him in perfect peace whose mind is stayed on you, because he trusts in you. Trust in the Lord forever, for the Lord God is an everlasting rock.” (Isaiah 26:3-4 ESV) The faith that honors God is believing His promises when they are not yet fulfilled; that He will answer our prayers although they are not yet answered; and that He cares for us even when there is no evidence of that care; that faith will be honored by Him. Honor Christ! What a dishonor it would be to our Savior to doubt the effectiveness of His blood to pardon and that of His righteousness to justify the very chief of sinners. God honors us with His grace when we do not deserve it. “For the wages of sin is death, but the free gift of God is eternal life in Christ Jesus our Lord.” (Romans 6:23 ESV) Genuineness of faith will ultimately result in the praise, glory, and honor of God through Jesus Christ our Lord. (1 Peter 1:7 ESV)


However, toothbrushing, flossing, or using oral rinses did not a make significant difference in whether those living in the same house became infected. Despite many people taking known infection control measures such as sanitizing toothbrushes and not sharing toothbrushes and toothpaste tubes, some cross-infection occurred, the authors wrote.
"This result can be interpreted to indicate the tongue as the main oral organ acting as a reservoir of COVID-19 and the importance of brushing to decrease the viral load of the individual carrier," wrote the group, led by María José González‑Olmo of the dentistry department at Rey Juan Carlos University in Madrid.
Habits of housemates
Global efforts to contain SARS-CoV-2, the virus that causes COVID-19, include maintaining good hygiene, keeping a safe distance from others, and sanitizing surfaces. Preliminary research has suggested that the mouth is a robust site for infection and transmission of the virus, and other evidence has indicated that maintaining good oral hygiene also may stop the spread. Here, researchers aimed to determine whether misuse of dental hygiene would facilitate the spread of COVID-19 among people living together.
Approximately 300 people living in Spain were sent an online questionnaire in April 2020, approximately four weeks after the country was locked down due to the pandemic. All respondents lived with and shared a bathroom with another person. Approximately 170 people were cross-infected from housemates, the researchers found.
Routines that may matter most
Approximately 34% of all participants reported that they brushed their teeth two or more times daily, about 20% flossed every day, about 15% used a daily rinse, and about 17% brushed their tongue every day. Tongue brushing was used more among those without transmission of the disease to other members of their households (t = 2.202; p = 0.029).
Of those in the cross-infected group, 127 shared toothbrush containers and 43 did not. In the group with no cross-infection, 65 shared brush containers and 67 didn't. Only a small segment of both groups disinfected their brushes with bleach daily. A total of 276 participants didn't disinfect their brushes. Of the 25 people who sanitized their brushes, about one-third still became infected with the novel coronavirus. In addition, about 5% of the cross-infected group (eight people) shared their toothbrush with someone they lived with. Of those who didn't get infected, only one shared a toothbrush.
The study had some limitations, according to the authors. For example, the data were self-reported, and the aerosol and surface viability of SARS-CoV-2 at the participants' homes could not be measured due to lockdowns.
Encourage good habits
Nevertheless, dentists should encourage patients to maintain good oral hygiene, including flossing and tongue brushing, and to avoid actions like toothbrush sharing or storing brushes with others.
"The use of inappropriate measures in the dental environment could contribute to the indirect transmission of COVID-19 between cohabitants," they wrote.
Copyright © 2020 DrBicuspid.com


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This paper investigates the degree to which victims of Sexual and Gender Based Violence (SGBV)1 access justice in Rwanda.
This study has used three main methods. The desk review has been used to explore and extract secondary data from laws, policy documents, studies and administrative and specialized reports. Interviews and focus group discussions have been conducted with key informants to gain first hand materials and insights. The findings suggest that Rwanda has achieved impressive progress in relation to the improvement of the legal and policy frameworks. The country has put in place an equally supportive institutional structure. However, access to justice for victims of SGBV is still complicated due to several practical reasons, including persistent legal gaps, limited capacity among service provider structures and staff and the lack of evidence for many cases related to SGBV.
Dr Aggée M.
Shyaka Mugabe is a Senior Lecturer and Senior Researcher at the Centre for Conflict Management of the University of Rwanda. He holds a PhD in Political ans Social Sciences from the Université Catholique de Louvain, Belgium (2005-2009). He has completed a postdoctorate fellowship at the School of Global Studies (SGS), Sweden.
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Shin Splints
January 17, 2017
The term "shin splints" refers to pain along the shin bone (also known as the tibia) — the large bone in the front of your lower leg. Shin splints are common in runners, dancers and military recruits. Medically known as medial tibial stress syndrome, shin splints often occur in athletes who have recently intensified or changed their training routines. The increased activity overworks the muscles, tendons and bone tissue.
Most cases of shin splints can be treated with rest, ice and other self-care measures. Wearing proper footwear and modifying your exercise routine can help prevent shin splints from recurring. Your podiatrists can advise you on this, and our podiatrists who specialize in myofascial release and kinesio taping can assist with the healing.
Shin Splints are not a condition covered by ACC as it is an overuse injury and is not from a direct incident.


NEW YORK (TheStreet) --
Barrick Gold ( ABX) stock is declining by 1.68% to $6.45 in early morning trading on Friday, as gold prices retreat after Federal Reserve Chairwoman Janet Yellen indicated in a speech yesterday that the central bank will hike interest rates before the year ends.
During a speech at the University of Massachusetts on Thursday afternoon, Yellen said that an interest rate increase could happen in 2015. The Fed's two remaining meetings this year are scheduled for October and December.
The assurance of an upcoming interest rate hike has strengthened the dollar and consequently weighed on gold prices, as dollar-traded gold becomes more expensive to foreign buyers,
The Wall Street Journal reports.
However, increased seasonal demand for gold from China in October to February should reverse some of the commodity's losses in upcoming months, according to
The Journal.
Gold for December delivery is lower by 0.62% to $1,146.70 per ounce on the COMEX this morning.
Barrick Gold is a gold mining company based in Toronto, Canada.
Separately, TheStreet Ratings team rates BARRICK GOLD CORP as a Sell with a ratings score of D. TheStreet Ratings Team has this to say about their recommendation:
We rate BARRICK GOLD CORP (ABX) a SELL. This is driven by some concerns, which we believe should have a greater impact than any strengths, and could make it more difficult for investors to achieve positive results compared to most of the stocks we cover. The company's weaknesses can be seen in multiple areas, such as its generally high debt management risk, disappointing return on equity and generally disappointing historical performance in the stock itself.
Highlights from the analysis by TheStreet Ratings Team goes as follows:
The debt-to-equity ratio of 1.26 is relatively high when compared with the industry average, suggesting a need for better debt level management. The company's current return on equity has slightly decreased from the same quarter one year prior. This implies a minor weakness in the organization. Compared to other companies in the Metals & Mining industry and the overall market, BARRICK GOLD CORP's return on equity significantly trails that of both the industry average and the S&P 500. ABX's stock share price has done very poorly compared to where it was a year ago: Despite any rallies, the net result is that it is down by 57.91%, which is also worse that the performance of the S&P 500 Index. Investors have so far failed to pay much attention to the earnings improvements the company has managed to achieve over the last quarter. Naturally, the overall market trend is bound to be a significant factor. However, in one sense, the stock's sharp decline last year is a positive for future investors, making it cheaper (in proportion to its earnings over the past year) than most other stocks in its industry. But due to other concerns, we feel the stock is still not a good buy right now. Despite the weak revenue results, ABX has significantly outperformed against the industry average of 45.0%. Since the same quarter one year prior, revenues slightly dropped by 9.2%. The declining revenue has not hurt the company's bottom line, with increasing earnings per share. 41.46% is the gross profit margin for BARRICK GOLD CORP which we consider to be strong. Regardless of ABX's high profit margin, it has managed to decrease from the same period last year. You can view the full analysis from the report here: ABX


The U.S. private sector added 200,000 jobs in September, which beat economists' expectations and has fueled speculation that the
Federal Reserve will hike interest rates before year end, Reuters reports.
Higher interest rates would likely strengthen the dollar, and a stronger dollar would weigh on demand for gold as the precious metal's relative cost would increase for foreign buyers.
"The dollar's rise has been a wrecking ball for commodity-sensitive assets this year," Ken Ford, president of
Warwick Valley Financial Advisors, told MarketWatch.
Gold for December delivery is sliding by 1.14% to $1,114.20 per ounce on the COMEX this afternoon.
Separately, TheStreet Ratings team rates YAMANA GOLD INC as a Sell with a ratings score of D. TheStreet Ratings Team has this to say about their recommendation:
We rate YAMANA GOLD INC (AUY) a SELL. This is driven by several weaknesses, which we believe should have a greater impact than any strengths, and could make it more difficult for investors to achieve positive results compared to most of the stocks we cover. The company's weaknesses can be seen in multiple areas, such as its feeble growth in its earnings per share, deteriorating net income, disappointing return on equity, weak operating cash flow and generally disappointing historical performance in the stock itself.
Highlights from the analysis by TheStreet Ratings Team goes as follows:
YAMANA GOLD INC has experienced a steep decline in earnings per share in the most recent quarter in comparison to its performance from the same quarter a year ago. The company has suffered a declining pattern earnings per share over the past two years. During the past fiscal year, YAMANA GOLD INC reported poor results of -$1.35 versus -$0.59 in the prior year. The company, on the basis of change in net income from the same quarter one year ago, has significantly underperformed when compared to that of the S&P 500 and the Metals & Mining industry. The net income has significantly decreased by 254.9% when compared to the same quarter one year ago, falling from $5.10 million to -$7.90 million. Return on equity has greatly decreased when compared to its ROE from the same quarter one year prior. This is a signal of major weakness within the corporation. Compared to other companies in the Metals & Mining industry and the overall market, YAMANA GOLD INC's return on equity significantly trails that of both the industry average and the S&P 500. Net operating cash flow has decreased to $121.80 million or 17.98% when compared to the same quarter last year. In addition, when comparing the cash generation rate to the industry average, the firm's growth is significantly lower. Despite any intermediate fluctuations, we have only bad news to report on this stock's performance over the last year: it has tumbled by 73.48%, worse than the S&P 500's performance. Consistent with the plunge in the stock price, the company's earnings per share are down 150.00% compared to the year-earlier quarter. Naturally, the overall market trend is bound to be a significant factor. However, in one sense, the stock's sharp decline last year is a positive for future investors, making it cheaper (in proportion to its earnings over the past year) than most other stocks in its industry. But due to other concerns, we feel the stock is still not a good buy right now. You can view the full analysis from the report here: AUY


2nd reading of ordinance allowing the keeping of chickens (hens) with some limitations. Given this is the second reading and the first was passed unanimously, this is being placed on the consent calendar. Consideration of establishment of ad-hoc committee to work on updating Town Center Specific Plan. This would consist of approving RFPs to go out to various vendors. Revisiting the Town Center Specific Plan for potential updates was one of the Council goals for 2019. While an RFP does not result in any cash outlays, if we were to move forward on any actual updates there would likely be a significant cost.
Because updates to the plan happen so infrequently and there are a great many laws that govern what can and cannot be included in a plan like this, the city is not staffed to handle this type of work with existing resources. As a result, if the City wishes to update this plan, it will likely have to engage in outside consultants who have professional expertise in this area.
To engage outside vendors for a project of this nature, we would send out a Request for Proposal (RFP) which gives guidelines and asks respondents to propose services to the city. Upon reviewing the responses, the level of services offered and an approximate price, the city may make a decision on whether or not to engage those services.
It would be a long process and involve significant staff time and public input and discussion. Doing something like this could be the first step in collectively deciding what the vision for our downtown will be. I was glad to be a voice advocating for this to be included as one of the Council goals this year.
If you have any thoughts or questions about any of these items please comment or contact me and I'll do my best to respond or find out more and report back.


The inability to lose weight despite increasing exercise and decreasing caloric intake may be due to low thyroid levels. An underactive thyroid gland can drastically slow down your metabolism, making weight loss a near impossibility. Without correcting thyroid levels, if you're suffering from an underactive thyroid, also known as hypothyroidism, you may continually struggle with your weight, not only having difficulty losing weight but also potentially gaining while you are working hard to lose it. Alternatively, an overactive thyroid gland, also known as hyperthyroidism, can drastically speed up the metabolism, causing the body to burn calories at a faster-than-normal rate resulting in unexplained weight loss.
This site offers information designed for educational purposes only. You should not rely on any information on this site as a substitute for professional medical advice, diagnosis, treatment, or as a substitute for, professional counseling care, advice, diagnosis, or treatment. If you have any concerns or questions about your health, you should always consult with a physician or other healthcare professional.


A new report finds that active enforcement against foreign bribery significantly decreased since 2018.
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When I started my first corporate level marketing position, I determined to “always only add.” I decided I was going to use my hands to build, not tear down, and that no matter who I worked with, I only wanted to add – no matter what.
One day, a man on my team (who passed a lot of judgment), was eating cake at a small birthday celebration at work. At the party, he told someone they were “living a sedentary life” and to “mind what you eat.” Later, when he passed my desk and fell into his chair saying, “Whew, I’m tired,” I wanted to respond, “Passing all that judgment can wear you out!” But I didn’t; instead I started drafting an email to a coworker about it.
While typing, I glanced at the only hot-pink sticky hanging around my monitors. “If I sent this,” I thought, “all I am doing is stirring up an ‘us-against-them’ mentality in a team environment.” I wasn’t looking at the good, I wasn’t building a relationship or respect – I wasn’t adding anything.
I don’t have to like everyone, but I do have to love everyone. People are people, and I am no greater. If I am going to love them, I need to love them all the time. God wants to and can use us at all moments, in every moment. At all times, I need to remember: if I am not adding, I am in the way.
I deleted the email.
Ginny’s Idea
Is there a goal you want to keep in mind at your workplace? Create your own post-it note to remind you along the way.


Olya Mastikhina, Byeong-Ui Moon, Kenneth Williams, Rupal Hatkar, Dakota Gustafson, Xuetao Sun, Margaret Koo, Alan Y.L. Lam, Yu Sun, Jason E. Fish, Edmond W.K. Young, ORCID ProfileSara S. Nunes
While interstitial fibrosis plays a significant role in heart failure, our understanding of disease progression in humans is limited. To address this limitation, we have engineered a cardiac-fibrosis-on-a-chip model consisting of a microfabricated device with live force measurement capabilities using co-cultured human cardiac fibroblasts and pluripotent stem cell-derived cardiomyocytes. Transforming growth factor-β was used as a trigger for fibrosis. Here, we have reproduced the classic hallmarks of fibrosis-induced heart failure including high collagen deposition, increased tissue stiffness, BNP secretion, and passive tension. Force of contraction was significantly decreased in fibrotic tissues that displayed a transcriptomic signature consistent with human cardiac fibrosis/heart failure. Treatment with an anti-fibrotic drug decreased tissue stiffness and BNP secretion, with corresponding changes in the transcriptomic signature. This model represents an accessible approach to study human heart failure in vitro, and allows for testing anti-fibrotic drugs while facilitating the real-time assessment of cardiomyocyte function.


PROJECT DOCUMENT REPOSITORY
During sustained periods of drought, landholders have come to appreciate the quality and persistence of native grasses under stress compared to non-native pasture species. How we manage these pastures is therefore essential to maintaining a productive and profitable livestock industry in NSW
1998 - 2005
Biological Control of Scotch Thistle and Paterson’s Curse
2015
Getting to the root cause of pasture legume (subclover) decline in NSW
2015 - 2017
Yield Prophet: Matching crop inputs with potential yield in Harden
Acknowledgements
This project was conducted by the Binalong Landcare Group (a subgroup of HMLG), with technical support from South East Local Land Services and NSW Department of Primary Industries (DPI).


Friday, August 14, 2020
Debbie Guerra, executive vice president at ACI Worldwide, observed that criminals are exploiting the card-not-present (CNP) space, especially buy online/pick up in store (BOPIS) and click-and-collect payment methods. "Fraudsters are targeting higher value items like electronics and luxury brand names, especially within newer channels such as curbside pick-up and in-parking lot pick-up," she said. "We continue to see a huge increase above industry averages in eCommerce sales year over year."
Will LaSala, security evangelist at OneSpan, has also seen a sharp increase in phishing attacks and new account takeovers during the COVID-19 crisis. "We can attribute up to $77 million caused by COVID-related attacks," he said. "Account takeover rose to the top during COVID and phishing attacks are up by 667 percent, making a huge impact across the board."
Guerra further noted that ecommerce activity was up by 19 percent during July 2020 compared to the previous year. ACI's findings were based on hundreds of millions of ecommerce transactions from the company's global merchant base. Notably, the data revealed a sharp uptick in the outdoor items category, which rose from 9 percent in 2019 to 12 percent in 2020.
Following are additional data points from the ACI study:
"We continue to see a huge increase above industry averages in ecommerce sales year over year," Guerra added. "As more brick-and-mortar stores reopen with COVID restrictions, we are seeing card-present transactions slightly increase; however, we expect the ecommerce trend to continue post-COVID as consumers experience the convenience and speed of digital payments."
LaSala mentioned that he has seen similar trends in the banking sector, where account takeover attacks have increased by 72 percent, much of it related to federal relief programs such as the Payroll Protection Plan, stimulus checks and unemployment benefits. Also, the Dark Web has made a huge cache of personally identifiable information available to fraudsters and array of tools designed to help them initiate new attacks.
"People mistakenly think of fraudsters as guys in hoodies who perpetrate crimes from their basements," LaSala said. "In reality, cybercrime is a well-organized global enterprise." For example, there are specialists within the multilayered threat landscape whose sole focus is writing attacks and designing email templates, he stated, while others purchase and use these products to launch attacks.
The criminals who design attacks are inventive and agile, LaSala noted. "They leverage the products by making a few simple tweaks and using them again," he said. "Through the years, we've seen reused and redeployed variants. That's why we recommend a holistic, multilayered approach that uses application shielding, dynamic passwords and artificial intelligence to protect mobile and cloud environments."
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The continued Covid-19 situation poses huge challenges regarding labor issues, personal data processing, public health, contracts, corporate governance, tax obligations and sanctions-related matters. This raises substantial questions and concerns from a tax and legal point of view. WTS Global, GTM’s international tax network, has compiled a 50+ country overview of information and guidance for multinational organizations on managing the evolving impacts of Covid-19.
[last updated October 2020]


Abstract : This contribution explores, within a critical narrative analysis framework, the changing role and in fact the gradual erasure of the linguist and the sociolinguist as a figure or character in the Occitan activist discourse. It seeks to draw parallels between this phenomenon and the concomitant development of the presence of the medical profession within that discourse, and to establish connections with a new interest for language transmission in the home. Parallel developments can be observed in Wales and other territories where a minority language is spoken, and beyond the erasure of the linguist as a figure, it questions the role of the individual and the collective in language revitalisation.


During the Space Telescope and Optical Reverberation Mapping Project (STORM)observations of NGC 5548, the continuum and emission-line variability becamede-correlated during the second half of the 6-month long observing campaign.Here we present Swift and Chandra X-ray spectra of NGC 5548 obtained as a partof the campaign. The Swift spectra show that excess flux (relative to apower-law continuum) in the soft X-ray band appears before the start of theanomalous emission-line behavior, peaks during the period of the anomaly, andthen declines. This is a model-independent result suggesting that the softexcess is related to the anomaly. We divide the Swift data into on- andoff-anomaly spectra to characterize the soft excess via spectral fitting. Thecause of the spectral differences is likely due to a change in the intrinsicspectrum rather than being due to variable obscuration or partial covering. TheChandra spectra have lower signal-to-noise ratios, but are consistent withSwift data. Our preferred model of the soft excess is emission from anoptically thick, warm Comptonizing corona, the effective optical depth of whichincreases during the anomaly. This model simultaneously explains all the threeobservations: the UV emission line flux decrease, the soft-excess increase, andthe emission line anomaly.
We present the results of an optical spectroscopic monitoring programtargeting NGC 5548 as part of a larger multi-wavelength reverberation mappingcampaign. The campaign spanned six months and achieved an almost daily cadencewith observations from five ground-based telescopes. The H$\beta$ and He II$\lambda$4686 broad emission-line light curves lag that of the 5100 $\AA$optical continuum by $4.17^{+0.36}_{-0.36}$ days and $0.79^{+0.35}_{-0.34}$days, respectively. The H$\beta$ lag relative to the 1158 $\AA$ ultravioletcontinuum light curve measured by the Hubble Space Telescope is roughly$\sim$50% longer than that measured against the optical continuum, and the lagdifference is consistent with the observed lag between the optical andultraviolet continua. This suggests that the characteristic radius of thebroad-line region is $\sim$50% larger than the value inferred from optical dataalone. We also measured velocity-resolved emission-line lags for H$\beta$ andfound a complex velocity-lag structure with shorter lags in the line wings,indicative of a broad-line region dominated by Keplerian motion. The responsesof both the H$\beta$ and He II $\lambda$4686 emission lines to the drivingcontinuum changed significantly halfway through the campaign, a phenomenon alsoobserved for C IV, Ly $\alpha$, He II(+O III]), and Si IV(+O IV]) during thesame monitoring period. Finally, given the optical luminosity of NGC 5548during our campaign, the measured H$\beta$ lag is a factor of five shorter thanthe expected value implied by the $R_\mathrm{BLR} - L_\mathrm{AGN}$ relationbased on the past behavior of NGC 5548.
During an intensive Hubble Space Telescope (HST) Cosmic Origins Spectrograph(COS) UV monitoring campaign of the Seyfert~1 galaxy NGC 5548 performed from2014 February to July, the normally highly correlated far-UV continuum andbroad emission-line variations decorrelated for ~60 to 70 days, starting ~75days after the first HST/COS observation. Following this anomalous state, theflux and variability of the broad emission lines returned to a more normalstate. This transient behavior, characterised by significant deficits in fluxand equivalent width of the strong broad UV emission lines, is the first of itskind to be unambiguously identified in an active galactic nucleus reverberationmapping campaign. The largest corresponding emission-line flux deficitsoccurred for the high-ionization collisionally excited lines, C IV and Si IV(+OIV]), and also He II(+O III]), while the anomaly in Ly-alpha was substantiallysmaller. This pattern of behavior indicates a depletion in the flux of photonswith E_{\rm ph} > 54 eV, relative to those near 13.6 eV. We suggest twoplausible mechanisms for the observed behavior: (i) temporary obscuration ofthe ionizing continuum incident upon BLR clouds by a moving veil of materiallying between the inner accretion disk and inner BLR, perhaps resulting from anepisodic ejection of material from the disk, or (ii) a temporary change in theintrinsic ionizing continuum spectral energy distribution resulting in adeficit of ionizing photons with energies > 54 eV, possibly due to a transientrestructuring of the Comptonizing atmosphere above the disk. Current evidenceappears to favor the latter explanation.


Turmeric Salve Fusion
The aromatic root of the turmeric plant has been used for centuries as a treatment for digestive disorders, inflammation, arthritis and infection. Many of turmeric's historic uses are not necessarily supported by scientific evidence. Nevertheless, turmeric supplements are commonly prescribed as a component of modern integrative medicine. According to the University of Maryland Medical Center, early studies suggest that turmeric can promote the health of your joints, blood vessels and digestive tract. Compounds in turmeric capsules may also offer hope as a complementary cancer treatment.


Clinically proven to deeply rehydrate the skin by increasing its ability to hold onto water for longer.
Super Drink contains 6 potent actives that boost hydration, therefore, reinforcing the skin’s physical integrity, giving it plump fullness. This powerful and natural formula contains essential actives that will help prevent transepidermal water loss and restore deep hydration, leaving the skin feeling smooth, healthy and bouncy.
Suitable for all skin types with deficiencies causing dehydration, dryness, thinning skin and fine lines.
20ml
Benefits
Super Actives are potent clinically proven plant-powered ingredients which have been encapsulated into a unique liposome. Liposomes are like biocompatible bubbles made from the same material as the skin’s cell membrane. These bubbles are filled with Serum Factories unique super active formulas and are delivered into the skin to target specific skin problems.
EAU DE SOURCE MARINE 80%: this water is rich in minerals and trace elements and stimulates lipid synthesis to reinforce the skin's barrier function and prevent water loss. It enhances cohesion between the dermis and the epidermis by increasing the number of hemidesmosomes which are mini spring-like structures that give the skin fullness and bounce.
MARIMOIST: proven to function as a water "attractor" and an excellent delivery system for water to the skin.
HYALURONIC ACID: can attract 1000 times its weight in water.
PENTAVITIN: long-lasting barrier repair features for long-term hydration, increasing the skin's moisture reservoir for 72 hours.
FUCOCERT: relieves the spread of inflammation and allergic reactions, increases hydration by 44% one hour after application.
LACTIC ACID: derived from fruits, this alpha hydroxy acid strengthens the acid mantle to balance healthy hydration levels.
How to Use
Shake serum before use. Apply 3-4 drops to a clean face in the morning and at night. Super Drink can be used alongside any serum, cream or oil for extra hydration. Always layer products on the skin from lightest to heaviest.
Formulated Without
Animal products, gluten, silicone, drying alcohols, SLS, parabens, phthalates, PEGs, ethanolamines, chemical sunscreens, synthetic fragrance, BHT, and BHA.


Having a beautiful home is great, but maintaining a front yard all year round can be costly. We’ve pulled together some front yard landscaping ideas (budget-friendly options included) to help you maintain the exterior appearance of your home.
A backyard can be many things. A place for entertaining, another home within the same vicinity of your beloved home, a haven for rest and relaxation, or an area for sport and activities.
Regardless of the many ways you may use your backyard, maximizing your space on a budget can often be a challenge.
Even if you were to hire a trusted landscaping service, you may not even know what backyard design to begin with. This is why we’ve decided to share with you the most common ideas we discuss during a one-on-one backyard landscaping design consultation.
The 59 Best Landscaping Blogs, Influencers, Instagram Accounts, Historical Sites, Magazines & Websites Landscaping Tips For Sandy Springs' Homeowners Authors
We love everything landscaping. We don't love writing too much, but we are giving it a go! We hope y'all enjoy it.


Our bankruptcy compliance and consumer bankruptcy litigation attorneys provide our clients’ bankruptcy departments with practical guidance both in and out of court. The team has decades of experience in consumer bankruptcy litigation and manages our clients’ caseloads efficiently and effectively.
The team also has leveraged prior matters to predict ranges of outcomes and contain legal costs. We apply that litigation experience – together with our experience guiding clients through a broad range of enforcement, remediation, and audit engagements – to provide practical regulatory and compliance advice and help our clients enhance the efficiency of their bankruptcy compliance management systems.
Bradley’s compliance and regulatory lawyers partner with in-house legal departments, default servicing management and operational staff at financial institutions helping them navigate the current bankruptcy regulatory environment. Our team includes lawyers that have served extended periods as temporary in-house bankruptcy counsel to various clients, including a Fortune 100 financial institution and one of the nation’s leading mortgage servicers.
Additionally, nearly all the members of our team have spent significant time on-site with our financial services clients, fully immersed in their bankruptcy departments and systems of record, working closely with key bankruptcy personnel to address the wide-ranging issues facing bankruptcy departments.
As trusted legal counsel, we bring our deep experience and informed perspective to helping clients avoid potential statutory or regulatory violations by addressing bankruptcy compliance and consumer financial protection issues proactively while keeping in mind the limitations on our clients’ financial, human, and IT resources. Our preventive measures eliminate or minimize litigation, financial repercussions, and other disruptions to our clients’ businesses.
To ensure compliance with the Bankruptcy Code provisions, Bankruptcy Rules, local rules, administrative orders, and servicing standards established by federal and state regulators, Bradley attorneys:
Our consumer bankruptcy litigation team represents financial services clients in numerous states, effectively containing their legal spend by guiding them through potential outcomes and helping them choose their battles wisely under the specific circumstances of each case. We understand the desire to resolve matters quickly when appropriate.
Through our deep bankruptcy experience and grasp of the relevant facts in each case, we often are able to negotiate early resolutions with opposing counsel. When an early resolution is not feasible, we zealously represent our clients’ positions before the bankruptcy court while containing costs as much as possible.
Matters we handle include:


A living will is a legal document that allows patients to provide healthcare providers with an outline of their wishes in the event they become incapacitated and unable to communicate their wishes themselves. The document often contains a provision for a person to be designated as healthcare power of attorney. This individual can speak on the patient’s behalf if he or she cannot do so.
Kentucky has specific living will laws as outlined in the Kentucky Living Will Directive Act. These are some of the highlights of this important law.
In Kentucky, a valid living will must have four components:
Living wills are revocable in the same way that traditional wills are. Methods of revocation include:
Revocation is effective immediately. This action overrides any previous written healthcare directives.
It’s worth noting that healthcare providers may follow living wills or advance directives created outside of Kentucky, so long as those directives are consistent with generally accepted medical practices. If a doctor cannot follow the instructions of the living will, he or she must inform the patient and the family, and cannot impede transferring the patient to a healthcare facility or doctor who can comply with the instructions.


Northern Beaches naturopathy belief is not to nurse symptoms but to treat the cause of imbalance.
$60.00
Omega Max fish oil
Highly concentrated dose of omega-3 polyunsaturated fatty acids. Each softgel contains: 650mg of eicosapentaenoic acid (EPA) and 400mg of docosahexaenoic acid (DHA).
Complies with the strictest quality standards set for acceptable levels for common contaminants including lead, cadmium, mercury, arsenic, dioxins and polychlorinated biphenyls (PCBs).
Sourced from small fish like Sardines, Anchovies and Whitebaits
Essential fatty acids, in the correct ratio, play a critical role in a wide variety of health related conditions.Recognising the roles that fish oils have in structure and physiologic functioning is a necessary step towards re-establishing EFA levels and ratios in the body.Used at the recommended dose EFAs are safe and devoid of toxicity but caution is required with high doses in patients scheduled for surgery and those currently on anticoagulant therapy.
DIRECTIONS
Adults: Take 1 softgel once daily or as directed by your healthcare


Importance of the Resilient Kids Boot Camp Game
The reality of life is that all human beings get stressed more often than they realize. Learning how to navigate through challenging events and manage stress is not easy. Over exposure to stress in children has been found to cause decreased academic performance, problems with attention, impulsive behaviors, increased depression and anxiety, sleep problems, and social struggles However, the ability to be remain calm during difficult events and utilize healthy coping skills to manage stress is a skill set that can be taught and developed.
Creative Ways To Use The Game
*Via teletherapy-For example, the cards can be "fanned" across the screen allowing the child to select a card. Discussion and problem solving to follow. Game board is used with family in between sessions to reinforce skills.
*In person
*With individuals or groups
*At home during family game time
*One skill card a day as a journal topic
*Role play
*Classroom guidance
Reasons To Play
*To help children build resiliency as they develop mindfulness and social skills, as well as learn how to regulate emotions and handle stress.
*Resilience training and practice will assist children find meaning in stressful events and learn how to stay present focused.
*Teach children a skill set to remain calm when placed into challenging events or situations.
Disclaimer: Please note that while playing this game may enhance coping skills, individual results and outcomes may vary.


Latin Name: Origanum marjorana Country: Hungary Method: steam distilled Status:
conventional
Description: Marjoram is a heady essential oil, with a deep, warming spice that is surrounded by a mild sweetness, and is most noted for its potent sedating effects.
It is useful for clearing bruises, healing minor wounds, and reducing toothaches. It has been shown to be beneficial when treating bronchitis, breathing difficulties, respiratory distress & infections, snoring, headaches, migraines, arthritis, muscle aches & stiffness, muscle spasms, sprains, rheumatism, irregular heartbeat, constipation, flatulence, digestive infections & complaints, and ulcers.
Marjoram is also known for assisting in regulating menstrual cycles, providing relief from painful periods, as well as tension, moodiness, and anxiety associated with PMS. It is considered an anaphrodisiac (curbs excessive sexual appetite) and may also assist in the removal (or repelling) of ticks.
This essential oil is excellent for tackling strong emotions and hindering fears. It is commonly used to address high stress issues, nervous tension, impatience, grief, panic, psychosis (to an extent), and sharp sadness. It may be used to combat feelings of claustrophobia, oppression, and irritability. It has been used to assist in the release of obsessions, and sometimes helps to relieve deep trauma.
The subtle (energetic) properties of Marjoram don't stray too far from its core psychological benefits. Said to allow individuals to embrace their unconscious fears, it allows one to step away from fears with comfort and support. It's a powerful tool for individuals suffering from grief, as it will assist in acceptance of deep, emotional loss. Marjoram is said to increase the attraction of love, happiness, health, and wealth, as well as promote our ability to give. It may be useful for those attempting a period of celibacy (particularly after a break up), and may help us to forgive without judgment or criticism, for no other reason than to have an untroubled heart.
Contraindications: Not recommended for use during the 1st trimester of pregnancy. Use caution around those with asthma, low blood pressure, and acute depression. It has been suggested that prolonged overuse may deaden the emotions, though regular proper use should not have this effect.


Περίληψη : The present dissertation explores the existence of offsetting movements between private and public saving, in a global level, for the period 1970-2015. The study of saving behavior aims to provide evidence in favor of Ricardian Equivalence or against it. Ricardian Equivalence is a proposition, initially formulated by David Ricardo and since then it has divided the economists. The proposition suggests that, under some assumptions, an individual should be indifferent about how a government will finance its spending (by taxation or debt issuing). A detailed literature review is presented, while the main hypothesis is tested with dynamic panel data econometric methods. The empirical results provide support forthe existence of partial Ricardian behavior but reject the hypothesis of pure Ricardian Equivalence. We also discuss the factors that make the existence and the examination of Ricardian Equivalence a complicated procedure.


DOI:10.1128/jb.177.14.4131-4133.1995 ABSTRACT
We have studied the response of Vibrio vulnificus to temperature shifts (23 to 13 degrees C) within the organism's permissive growth range. Cold shift induced a diminution in protein synthesis. Following a short lag, cells began growth at a new rate. Forty proteins were induced by this downshift.


Genetic changes involved in the metaplastic progression from squamous esophageal mucosa toward Barrett's metaplasia and adenocarcinoma are almost unknown. Several evidences suggest that some miRNAs are differentially expressed in Barrett's esophagus (BE) and esophageal adenocarcinoma. Among these, miR-143, miR-145, miR-194, miR-203, miR-205, miR-215 appear to have a key role in metaplasia and neoplastic progression. The aim of this study was to analyze deregulated miRNAs in serum and esophageal mucosal tissue biopsies to identify new biomarkers that could be associated with different stages of esophageal disease. Esophageal mucosal tissue biopsies and blood samples were collected and analyzed for BE diagnosis. Quantitative Real-time PCR was used to compare miRNA expression levels in serum and 60 disease/ normal-paired tissues from 30 patients diagnosed with esophagitis, columnar-lined oesophagus (CLO) or BE. MiRNA expression analysis showed that miR-143, miR-145, miR-194 and miR-215 levels were significantly higher, while miR-203 and miR-205 were lower in BE tissues compared with their corresponding normal tissues. Esophageal mucosa analysis of patients with CLO and esophagitis showed that these miRNAs were similarly deregulated but to a lesser extent keeping the same trend and CLO appeared as intermediate step between esophagitis and BE. Analysis on circulating miRNA levels confirmed that miR-194 and miR-215 were significantly upregulated in both BE and CLO compared to esophagitis, while miR-143 was significantly upregulated only in the Barrett group. These findings suggest that miRNAs may be involved in neoplastic/ metaplastic progression and miRNA analysis might be useful for progression risk prediction as well as for monitoring of BE/CLO patients.
Lingua originale English pagine (da-a) 47821-47830 Numero di pagine 10 Rivista Oncotarget Volume 7 Stato di pubblicazione Published - 2016


Recent PhD graduate Lawrence Williams has published an article in
Frontiers in Sociology entitled, “How Career Identity Shapes the Meaning of Work for Referred Employees.” The article dismantles previous sociological explanations surrounding the phenomenon of referred employees having longer tenures than non-referred employees. Within the study, the author demonstrates how career plans or career identity shaped how information and peer support led to respondents either staying in or leaving their jobs.
Lawrence Williams recently defended his dissertation in the Department of Sociology at the University of Toronto. His research interests lie within sociological theory, sociology of culture, and deviance. His current research focuses on how individuals working in the field of customer service understand their careers and find meaning at work. It also examines the role of intuition in major life decisions.
We have posted the citation and the abstract below. The full text is available through
Frontiers in Sociology, here.
Williams, Lawrence H. 2019. “How Career Identity Shapes the Meaning of Work for Referred Employees.”
Frontiers in Sociology 3.
Sociological explanations for why referred employees typically have longer tenures than non-referred employees tend to be either that referred employees enter their jobs possessing a clearer sense of employer expectations or that they often receive support from their referrers while on the job. However, through analysis of work-history interviews conducted with salespersons in Toronto, Canada, I find that the significance of each of these factors for a person’s tenure depends on their career plans. For individuals with clear career plans, information mattered but support was less important. Conversely, for individuals with unclear career plans, support mattered but information was less important. I find that this divergence was based on the fact that individuals who had clearer career plans cared more about the fit they had with the
tasksthey performed in jobs which they were referred into while those with unclear plans tended to be more concerned about their overall fit with the job’s culture. I examine this difference in job satisfaction by demonstrating how the combination of information and support respondents had at any given job led them to either support, interrogate, or re-route their career plans differently based on the initial clarity of these plans. Based on these findings, I argue that the role that referrals play in shaping turnover intentions should be nested within individuals’ career identities. Doing so prevents researchers from seeing turnover intentions as being solely based on expectations at the time of hire or on connections made, strengthened, or weakened on-the-job and, instead, necessitates a more grounded view of turnover decisions.


Defining a formal sales methodology helps the sales organization realize repeatable and scalable results by replicating the behaviors and activities of high performers. However, companies often adopt a new sales methodology with little understanding of what they are getting and what it will take to ensure a successful implementation and ongoing engagement. This session will explore the various types of sales methodologies, the business needs that a methodology addresses, and a process for internal discovery, methodology definition and alignment to sales outcomes.
This session will provide the following benefits:


Successful real estate developers and development attorneys must effectively anticipate and manage risk. Managing visible and known risks seems simple; what separates the great from the good is the ability to anticipate, plan for, and develop contingencies for unknown risk scenarios. Failure to account for these risks can be catastrophic. Hurricanes Harvey and Katrina unveiled the stark consequences of the failure to adequately plan for catastrophic events, showcasing chemical-plant explosions, flooded buildings, and lost real estate assets. Extreme weather conditions are increasing in severity and frequency, and oceans are rising, so resilient real estate developers must adapt and engineer buildings and site configurations that are sustainable under changing climatic conditions.
Premium Content For: Environment, Energy, and Resources Section


CTS are your trusted provider of Commercial Intruder, Fire, CCTV and Access Control Systems
As a business, you have duty to ensure that your staff and anyone visiting your premises are safe and secure. This can be achieved by having a professionally installed and maintained security system, which will include Intruder Alarm, Fire, CCTV and Access Control Systems. These systems protect both property and people.
Additionally, you may benefit from lower insurance premiums if your business is adequately protected from burglary and fire.
You should choose a reputable installer that can provide you with a security system that is certified and installed to the latest industry standards, and who can prove their credentials to you.
As an NSI Gold approved company employing only the best staff, which includes vetted and highly skilled security system engineers, you can rest assured that we will design and install a security system for you, to the highest standards, using the most up to date equipment and technology.
We are proud to have worked with many commercial clients across East Anglia and further afield, from small shops to international companies occupying large commercial premises in the UK. We are confident that our clients would vouch for our excellent standards of service, both before, during and after installation.


Unless your plan terms provide otherwise, the salary (elective) deferral limit is applied uniformly to the compensation that the employee receives throughout the year. Compensation and contribution limits are subject to annual cost-of-living adjustments. The annual limits are: salary deferrals - $19,500 in 2020 and 2021 ($19,000 in 2019), plus $6,500 in 2020 and 2021 ($6,000 in 2015 - 2019) if the employee is age 50 or older (IRC Sections 402(g) and 414(v)) annual compensation - $290,000 in 2021, $285,000 in 2020, $280,000 in 2019 (IRC Section 401(a)(17)) total employee and employer contributions (including forfeitures) - the lesser of 100% of an employee’s compensation or $58,000 for 2021 ($57,000 for 2020 not including "catch-up" elective deferrals of $6,500 in 2020 and 2021 ($6,000 in 2015 - 2019) for employees age 50 or older) (IRC section 415(c)) Example: Mary, age 49, whose annual compensation is $360,000 ($30,000 per month), elects to defer $1,500 per calendar month, up to $19,000 for the 2019 year. Mary may contribute to the plan until she reaches her annual deferral limit of $19,000 even though her compensation will exceed the annual limit of $280,000 in October. Employer matching contributions If your plan provides for matching contributions, you must follow the plan’s match formula. Example: Your plan requires a match of 50% on salary deferrals that do not exceed 5% of compensation. Although Mary earned $360,000, your plan can only use up to $280,000 of her compensation when applying the matching formula for 2019. Mary’s matching contribution would be $7,000 (50% x (5% x $280,000)). Although Mary makes salary deferrals of $19,000, only $14,000 (5% of $280,000) will be matched. She must receive a matching contribution of $7,000 (50% x $14,000) under the terms of the plan. What does your plan say? Although not common, a plan can specifically require that salary deferrals cease once a participant’s compensation reaches the annual limit. If your plan specifies that salary deferrals be based on a participant’s first $280,000 of compensation, then you must stop allowing Mary to make salary deferrals when her year-to-date compensation reaches $280,000, even though she hasn’t reached the annual $19,000 limit on salary deferrals, and must base the employer match on her actual deferrals. Additional resources Retirement Topics – Contributions FAQs: Contributions Publication 560, Retirement Plans for Small Business (SEP, SIMPLE, and Qualified Plans)


Predicting cognitive resilience from midlife lifestyle and multi-modal MRI: A 30-year prospective cohort study. Topiwala A., Suri S., Allan C., Valkanova V., Filippini N., Sexton CE., Heise V., Zsoldos E., Mahmood A., Singh-Manoux A., Mackay CE., Kivimäki M., Ebmeier KP.
BACKGROUND: There is significant heterogeneity in the clinical expression of structural brain abnormalities, including Alzheimer's disease biomarkers. Some individuals preserve their memory despite the presence of risk factors or pathological brain changes, indicating resilience. We aimed to test whether resilient individuals could be distinguished from those who develop cognitive impairment, using sociodemographic variables and neuroimaging. METHODS: We included 550 older adults participating in the Whitehall II study with longitudinal data, cognitive test results, and multi-modal MRI. Hippocampal atrophy was defined as Scheltens Scores >0. Resilient individuals (n = 184) were defined by high cognitive performance despite hippocampal atrophy (HA). Non-resilient participants (n = 133) were defined by low cognitive performance (≥1.5 standard deviations (S.D.) below the group mean) in the presence of HA. Dynamic and static exposures were evaluated for their ability to predict later resilience status using multivariable logistic regression. In a brain-wide analysis we tested for group differences in the integrity of white matter (structural connectivity) and resting-state networks (functional connectivity). FINDINGS: Younger age (OR: 0.87, 95% CI: 0.83 to 0.92, p<0.001), higher premorbid FSIQ (OR: 1.06, 95% CI: 1.03 to 1.10, p<0.0001) and social class (OR 1 vs. 3: 4.99, 95% CI: 1.30 to 19.16, p = 0.02, OR 2 vs. 3: 8.43, 95% CI: 1.80 to 39.45, p = 0.007) were independently associated with resilience. Resilient individuals could be differentiated from non-resilient participants by higher fractional anisotropy (FA), and less association between anterior and posterior resting state networks. Higher FA had a significantly more positive effect on cognitive performance in participants with HA, compared to those without. CONCLUSIONS: Resilient individuals could be distinguished from those who developed impairments on the basis of sociodemographic characteristics, brain structural and functional connectivity, but not midlife lifestyles. There was a synergistic deleterious effect of hippocampal atrophy and poor white matter integrity on cognitive performance. Exploiting and supporting neural correlates of resilience could offer a fresh approach to postpone or avoid the appearance of clinical symptoms.


Victims of Lawsuit Claim Support in a case against Xarelto. Doctors claim that it had unlisted and daunting side effects.
Drs. John C. Hwang and Judy Hun observed patients from their practice who were currently participating in a long-term blood thinner regimen and ranged in age from 70 to 89. While they were originally taking more traditional medications, they switched to Xarelto after its FDA approval in 2011. According to empirical observation, these patients showed a marked increase in incidents of vitreous hemorrhages or eye-bleeding that appeared to coincide with their change in medication. Victims of Lawsuit Claim Support after receiving side effects. The doctors noted that the bleeding events were most likely to occur in those who had an established history of blood thinner use, such as warfarin, and switched to the new-generation anticoagulant. Hwang and Hun published their complete findings in the June 2015 issue of JAMA Ophthalmology, and noted, “In all cases, an acute vitreous hemorrhage occurred shortly after rivaroxaban (Xarelto) treatment was initiated.” Another landmark study was published in the April 2015 issue of the British Medical Journal (BMJ) that indicated as high as a two-fold increase in the risk for stomach bleeds by patients taking Xarelto in lieu of warfarin. For the purposes of the study, investigators screened nearly 46,000 complete medical histories. It was noted that the bleeding events were most common in those who had been taking warfarin, but weaned off the drug in favor of the promising new treatment option presented by Xarelto. In the United States, more than 2,800 individual cases against Xarelto and its manufacturers have been consolidated to form the multidistrict litigation (MDL) No. 2592. The common allegations of the plaintiffs in these cases include a substantially increased risk of catastrophic bleeding events, injury, and even death. Judge Eldon Fallon has been appointed to oversee the MDL proceedings in the Eastern District Court of Louisiana.
Originally Posted by Laurence Banville of the Legal Examiner Victims of Lawsuit Claim Support – Ball and Bonholtzer Trail attorney – Los Angeles


Hypertrophy, hyperplasia and altered mucus secretion from the respiratory submucosal glands (SMG) are characteristics of airway diseases such as cystic
fibrosis, asthma and chronic bronchitis. More commonly, hyper-secretion of the nasal SMGs contributes to allergic rhinitis and upper airway infection. Considering the role of these glands in disease states, there is a significant dearth in understanding the molecular signals that regulate SMG development and patterning. Due to the imperative role of FGF signalling during the development of other branched structures, we investigated the role of Fgf10 during initiation and branching morphogenesis of murine nasal SMGs. Fgf10 is expressed in the mesenchyme around developing SMGs while expression of its receptor Fgfr2 is seen within glandular epithelial cells. In the Fgf10 null embryo, Steno's gland and the maxillary sinus gland were completely absent while other neighbouring nasal glands showed normal duct elongation but defective branching. Interestingly, the medial nasal glands were present in Fgf10 homozygotes but missing in Fgfr2b mutants, with expression of Fgf7 specifically expressed around these developing glands, indicating that Fgf7 might compensate for loss of Fgf10 in this group of glands. Intriguingly the lateral nasal glands were only mildly affected by loss of FGF signalling, while these glands were missing in Eda mutant mice, where the Steno's and maxillary sinus gland developed as normal. This analysis reveals that regulation of nasal gland development is complex with different subsets of glands being regulated by different signalling pathways. This analysis helps shed light on the nasal gland defects observed in patients with hypohidrotic ectodermal dysplasia (HED) (defect EDA pathway) and LADD syndrome (defect FGFR2b pathway). Submucosal gland (SMGs), FGF10, EDA, branching morphogenesis
ID: 27620637


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Final published version, 6.12 MB, PDF document
Licence: Creative Commons: Attribution (CC-BY)
Ageing has a profound effect on the immune system, termed immunosenescence, resulting in increased incidence and severity of infections and decreased efficacy of vaccinations. We previously showed that immunosurveillance in the intestine, achieved primarily through antigen sampling M cells in the follicle associated epithelium (FAE) of Peyer’s patches, was compromised during ageing due to a decline in M cell functional maturation. The intestinal microbiota also changes significantly with age, but whether this affects M cell maturation was not known. We show that housing of aged mice on used bedding from young mice, or treatment with bacterial flagellin, were each sufficient to enhance the functional maturation of M cells in Peyer’s
patches. An understanding of the mechanisms underlying the influence of the intestinal microbiota on M cells has the potential to lead to new methods to enhance he efficacy of oral vaccination in aged individuals M cells, Peyer’s patches, small intestine, mucosal immunity, ageing, microbiota, flagellin, IgA
ID: 146469646


Abstract
Published evidence indicates that nearly 60% of blueberry-producing countries experience yield instability. Yield is a complex trait determined by genetic and environmental factors. Here, using physiological and biochemical approaches, we tested the hypothesis that yield instability results from year-to-year environmental variation that limits carbon assimilation, storage and partitioning. The data indicate that fruit development depends primarily on the daily production of non-structural carbohydrates by leaves, and there is no accumulation of a starch buffer to allow continuous ripening under conditions limiting for photosynthesis. Photosynthesis was saturated at moderate light irradiance and this was mainly due to stomatal and biochemical limitations. In a dynamic light environment, photosynthesis was further limited by slow stomatal response to increasing light. Finally, labelling with 13 CO 2 at specific stages of fruit development revealed a relatively even distribution of newly assimilated carbon between stems, roots and fruits, suggesting that the fruit is not a strong sink. We conclude that a significant component of yield variability results from limitations in photosynthetic efficiency that are compounded by an inability to accumulate starch reserves in blueberry storage tissues in a typical northern European environment. This work informs techniques for improving agronomic management and indicates key traits required for yield stability in such environments.
Keywords 13 CO 2 -labelling Vaccinium carbon assimilation carbon storage corymbosum sink tissues starch yield


The STAT3 Signaling Pathway affects Sca1+ Bone-associated Progenitors in the Hematopoetic Stem Cell Niche Author: Michael Wong Mentors: Xingbin Hu, Postdoctoral Fellow, City of Hope Ching-Cheng Chen, Principal Investigator, City of Hope
The hematopoetic niche is the core regulation machinery for hematopoietic stem cell (HSC) differentiation and self-renewal in bone marrow. STAT3 is a highly conserved signaling pathway that is involved in cell proliferation and cell cycle, but it is not yet known whether the STAT3 signal is a definite player in niche constitution. We previously confirmed that Sca1+ bone associated progenitors can differentiate into stroma lineages to maintain HSCs. This study aims to functionally characterize the role of the STAT3 signal on Sca1+ cells and their function in the hematopoetic niche. A transgenic osteotrix:STAT3 knockout mouse model was used for analysis. By flow cytometry, Sca1+ populations were isolated and examined. It was observed that STAT3 knockout populations exhibited increased myeloid lineages in peripheral blood and spleen samples. The myeloid lineage changes are believed to be a result of the Sca1+ bone associated progenitors because, firstly, the osteotrix:STAT3 knockout mice exhibited significantly increased Sca1+ sub-populations, and secondly, the down-regulated STAT3 Sca1+ cells co-cultured long-term improved the HSCs' engraftment in bone marrow transplantation assays. It was also observed in vitro that down-regulated STAT3 Sca1+ cells’ proliferation also rose. This observation is consistent with the earlier findings that Sca1+ populations increase when STAT3 is down-regulated or knocked out. This study is significant in clarifying how the STAT3 pathway participates in the niche constitution, a key component in HSC maintenance.
Presented by: Michael Wong Date: Saturday, November 17, 2012 Time: 3:45 PM — 4:00 PM Room: Bell Tower 2515 Presentation Type: Oral Presentation Discipline: Biology


This focus report provides a summary of States’ Social Services Block Grant (SSBG) expenditures for, and recipients of, support services for older adults across all SSBG service categories. The SSBG program defines older adults as individuals 60 years of age and older. An analysis of 6-year trends in the use of SSBG expenditures for these services is also included.


Interested in becoming a foster carer, but want to know more about if you can foster? Perhaps you’re a single parent, or you’re currently renting a property and wondering if this affects your application? Our detailed guide breaks down fostering requirements, as well as addressing some myths and misconceptions around who can become a foster carer.
In order to become a foster carer, as a first port of call, there are three primary fostering requirements you need to have:
However, there are other requirements that you’ll need to become a foster carer – such as a home where children under five are placed should be non-smoking, and your home should not have any aggressive pets or dangerous pets. Often with fostering, there are many misconceptions regarding whether you can foster based on your career, experience or living situation. That’s why we put together our top 10 fostering myths guide which highlights the most common misconceptions about who can foster.
Whether you apply through your local authority or through an independent fostering agency, such as Capstone Foster Care, during the application process, you will undergo a health check and all members of your household over the age of 18 will undergo a Disclosure and Barring (DBS) check. Foster care training, help and support are provided during the application process and throughout your fostering work.
If you have any questions regarding who can foster, or wondering ‘Can I foster if…?’, our detailed guide can help. Alternatively, get in touch with a member of our expert team here at Capstone Foster Care.
You can chat with us online and you can get the answers to your questions immediately.


13,000 people are injured each year from ordinary objects that are unsecured in car accidents. It is vital that items in your car are secured safely and properly. At the moment of impact a seemingly innocuous item can be propelled to lethal speeds.
“Sometimes the most dangerous things we face in an accident can come from inside the car” Practice safe cargo securing
It is our recommendation/belief that all our items are stowed securely in the car.
-Place large items in the car trunk and fasten them securely
-Smaller items such as phones should be placed in compartments or even in your pocket
-Water bottles should be placed securely into their holders
-Briefcases and purses should be placed in the car trunk
-Ideally heavy items should be placed up against the rear of the passenger seat in the trunk
-Straps and tie downs should be used where possible
-Small and pointy objects should be placed in boxes away from passengers
-Pets should be in secured carriers at all times
The below German crash test videos demonstrate how dangerous unsecured luggage can be.


- Discussion:
- deformity is characterized by severe angular deformity with a prominent gibbus at the apex of the curve;
- etiology involves either failure of
segmentationor defect in formationof vertebral body elements;
-
defect of formation:
- failure of formation of the anterior elements produces the worst deformity;
- prognosis for defect in formation is considerably worse;
- natural history involves relentless progression of deformity;
-
sequelae:
-
paraplegiacommonly results if untreated;
- breakdown of the overlying soft tissues;
- compression of the abdominal viscera;
- impairment of pulmonary function;
- poor sitting posture;
-
defect of segmentation:
- slightly better prognosis;
- produces a more rounded kyphotic shape;
- deformity progresses more slowly and paraplegia is uncommon;
- Posterior Fusion: - in children < 5 yrs w/ curves < 55 deg, only an situ posterior arthrodesis is required since some spontaneous correction of kyphosis will occur with continued growth; - posterior fusion may have wider indications w/ kyphosis due to failure of segmentation (as opposed to failure of formation); - posterior kyphectomy & arthrodesis involve meticulous care of tissues; - resection of the non-functioning cord at apex of the deformity; - water-tight dural closure, w/ care being taken not to occlude terminal end of normal spinal cord at site of transection of cord; - bivalve total-contact orthosis is used to support trunk until fusion is solid; - Anterior & Posterior Fusion: - combined anterior & posterior fusion is indicated for children > 5 years, and curves > 55 deg; - paralytic deformity: - reconstruction begins w/ anterior release w/ interbody arthrodesis; - decompression of spinal cord anteriorly is required;; - as a staged procedure, posterior arthrodesis is followed by segmental spinal fixation to pelvis; - reduction: - correction of kyphotic defomrity carries a high risk of paraplegia, esp when it is tried preoperatively w/ traction; - this will stretch cord over fixed kyphotic deformity; - congenital kyphosis may be corrected intraoperatively if intra operative cord monitoring if available; - anterior arthrodesis: - requires strut graft as well as interbody arthrodesis; - anterior unsegmented bar will develop in growing child if interbody arthrodesis is not added to procedure since unfused vertebral bodies will continue to grow & contribute to the deformity; - strut graft is placed as close to vertebral bodies as possible to reduce the risk of pseudoarthrosis; - vertebral resection: - w/ severe deformity present at birth, vertebral resection and a short arthrodesis may be required for closure of overlying soft tissues; - loss of correction with growth is common, and arthrodesis of entire spine may be required by age 10 yrs
Congenital kyphosis due to defects of anterior segmentation.


Vision dominates audition in adults but not children: a meta-analysis of the Colavita effect
Hirst, Rebecca J. and Cragg, Lucy and Allen, Harriet A. (2018)
Abstract
The Colavita effect occurs when participants respond only to the visual element of an audio-visual stimulus. This visual dominance effect is proposed to arise from asymmetric facilitation and inhibition between modalities. It has also been proposed that, unlike adults, children appear predisposed to auditory information. We provide the first quantitative synthesis of studies exploring the Colavita effect, combining data from 70 experiments across 14 studies. A mixed-meta-regression model was applied to assess whether the Colavita effect is influenced by methodological factors and age group tested. Studies reporting response time data were used to test for the presence of asymmetrical facilitation between modalities. Studies with adult participants yielded a medium, approaching large, effect size. Studies exploring the Colavita effect in children yielded no Colavita effect. Across adult and child studies, no methodological factors influenced the effect. Contrary to asymmetrical facilitation, response time data suggested a general slowing under bimodal conditions. These findings suggest that whilst vision dominates in adults, this effect is absent in childhood.
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The proliferation of molecular diagnostics is bringing a tidal wave of complexity, cost and quality issues for payers, clinicians and laboratories. As a result, payers are accelerating efforts to appropriately manage (Read the full article)
Lab Processes and Procedures
Medical laboratories are a critical part of the healthcare system. A patient’s diagnosis and treatment are often based on test results, and an incorrect laboratory test result could lead to (Read the full article)


Jackie Burke’s presentation that focused on the challenges for trauma exposed workforces. It explores the multiple meanings of ‘complex trauma’ and the implications for women’s wellbeing and safety from violence. Key discussions include:
The Challenge of Responding to Multiple Needs in the Right Order The Challenge of Responding Effectively to “Needs in Disguise” The Challenge of Problem Saturated Work The Challenge of Vicarious Traumatisation


One of our clients, a leading global automotive supplier with operations across Europe, was struggling with fragmented Finance processes that inhibited performance. Other issues it faced included a high degree of manual intervention, lack of standardization and the expense of maintaining a high percentage of staff in relatively high cost European locations. To align cost levels toward global best practices and drive improved data harmonization, the company opted for a shared services model. Chazey was engaged to develop a business case (see the part one of this series) and subsequently help launch a new, pan-Europe shared services center.
This article explores how the company implemented the end-to-end rollout of its Finance shared services after the pre-launch of the business case development phase. It highlights the Design phase as crucial to successful shared services implementation and share a planning roadmap.
The paper forms part of “How to implement a new shared services center” series as part two. Part one explains shared services feasibility study and business case development.


The injustices of high- versus low-skilled temporary labour migration programs: With evidence from Canada
Often, however, these critics fail to distinguish between high- and low-skilled TLMP, the stipulations of which are often quite distinct. Where they do distinguish between them, the common conclusion is that only low-skilled TLMP pose problems of justice which require immediate action. Patti Lenard will examine these assumptions. She argues that both low- and high-skilled TLMP often pose problems of justice, and that while some of these apply only to high- or low-skilled programs, there are others which apply to both. She will illustrate these dilemmas by reference to the Canadian case, where the government has expanded the number of migrants participating in TLMP significantly over the last 10 years.


Abstract
Intracranial subdural hemorrhage is a rare complication of lumbar puncture. Caudal traction and tear of the subdural veins due to negative pressure caused by leakage of cerebrospinal fluid (CSF) following lumbar puncture (LP) is the mechanism. Prolonged headache or neurological symptoms following LP should warrant cross-sectional imaging to rule out subdural hemorrhage as it can be fatal. We report a case of subdural hemorrhage following LP in a patient with suspected meningitis and communicating hydrocephalus.
Keywords Hydrocephalus Lumbar puncture Meningitis MRI Subdural hemorrhage


Â© 2015 Taylor & Francis. Much academic research on migrant mothers focuses on mothers who are separated from their children, often through their integration into global care chains, or on mothers within the context of family migration. This paper argues that co-resident migrant mothers' experiences provide an important window on the complexities of the migration experience. Using a specific case study of Ireland, and drawing from a broader longitudinal research project that focuses on recent migrants, the paper explores migrant mothers' understandings and experiences of belonging and not-belonging. We argue that structural obstacles and cultural understanding of care actively conspire to undermine migrant mothers' potential to develop place-belongingness. Interviewees' discussions of their status as full-time mothers were often framed through images of ideal motherhood, but equally highlighted how the absence of affordable childcare and family members isolates them and prevents them from creating a sense of belonging outside of the process of mothering and the home.


Estimated reading time: < 1 Minute 20 July 2020
In 2017, the UK, Scottish and Welsh Governments agreed they would need to manage policy divergence between the different parts of the UK in some areas covered by EU law.
They agreed to establish common frameworks on the basis of set criteria. These criteria included enabling the functioning of the UK internal market, while acknowledging policy divergence; ensuring compliance with international obligations; and ensuring the UK can negotiate, enter into and implement new international agreements, including trade agreements.
This briefing summarises developments to early July 2020, considering:
the progress of the common frameworks programme; how common frameworks could interact with UK international obligations and the UK internal market; and how law and policy have developed in policy areas where common frameworks are planned, including the development of interim arrangements.
This briefing charts the developments that took place before the publication of the UK Government’s
internal market white paper. We will publish a second briefing which looks in more detail at the internal market proposals themselves.


5. WORKING WITH CARE AND SUPPORT PROVIDERS 5.1 Introduction
Safeguarding is everyone’s business. This section considers a range of issues about quality and safety, positive practice, safeguarding concerns and managing large scale enquiries. Partnerships between safeguarding and commissioning functions and their interdependent roles and responsibilities towards providers are explored. It is essential to know what works well to support a positive culture of cooperation and information sharing with joint accountability for risk and benefits. It identifies the role and responsibilities of the five groups that influence quality:
Professionals and staff Commissioners and funders(Local authorities, CCG and NHS England) Regulators(CQC, Trust Development Agency, Monitor) The public, including adults who use services, their families and carers Providers- A provider for the purposes of this policy and procedure is any care or health provider who delivers support and care to a group of individuals. This would include but is not exclusive to the following: Domiciliary Care Providers Residential Care Homes Nursing Homes Supported Living Private hospitals NHS provision Day Care/Opportunities Providers Rehabilitation Units for people who misuse drugs or alcohol Voluntary agencies Respite provision Hospices
By working in partnership these groups can assist early identification if providers are at risk of falling standards that might lead to wider concerns and the need for safeguarding intervention. There is a clear responsibility on commissioners and providers to ensure safe, quality services that will reduce the need for safeguarding interventions.
This section is relevant to all providers not just those in the CQC inspection regime. The CQC are responsible for inspecting and monitoring providers registered under the Health and Social Care Act 2008 . It has statutory powers to inspect how well services are performing against ‘Fundamental Standards’ of quality and safety, and can take proportionate enforcement action to ensure providers improve where there is poor care.
This section explores work with providers as a means for responding to potential business failure (contracts and commissioning responsibilities) and details how allegations of organisational abuse are managed where safeguarding concerns are identified as serious matters within an organisation as opposed to single concerns that may be addressed under Section 42 (safeguarding responsibilities). Safeguarding concerns in this sense relate to patterns of reported abuse or neglect about one provider, or where a single concern indicates a serious matter that warrants closer inspection under adult safeguarding processes. In some instances, safeguarding action may be initiated following a Safeguarding Adult Review, or run in parallel to one.
The focus of this section is on prevention, in particular actions that might be taken in response to concerns about quality issues, to reduce the risk of escalation to safety and safeguarding issues.
Finally, this section aims to ensure that people have a voice in influencing how services are delivered and where there are concerns, and how their views and experiences lay at the heart of improvements.


Recreational outings
For five years, Mary lived in Cape Town and regularly took the children out for exciting excursions on the weekends. Now, she commutes to Cape Town once or twice a year for a month at a time. The older children have been on safaris, wilderness reserves and wellness retreats to learn more about their own heritage and art history. These outings give the children invaluable opportunities to encounter new experiences, such as art lessons and exhibitions, exposing them to everyday life and practices that would otherwise have remained unknown to them. Many of the children have never been to a real restaurant before or even used cutlery to eat a meal. In addition to this, good nutrition is also a vital part of maintaining the children’s health, ensuring that their bodies receive the proper sustenance for a good life. These outings show them another side of life, one where every moment is not a struggle, where food and fun are a reality and they can simply relax and enjoy the happy moments.
What the children love most though is when Mary takes them into her own home on weekends. For the past ten years, she has spent countless hours with them, teaching them how to swim and dive, cook and providing the children with general life lessons in a real home environment.
A Boy’s story
On one occasion, Mary and four of the vulnerable children from the townships children’s home, were on a weekend trip to the circus after having spent the morning at her home, bathing and having breakfast. While driving to the circus, a 7-year-old boy looked up from the passenger seat beside her and said “Mary, I don’t want to die.” After a heartbreaking moment, she turned to him and reassured him that if he continued to take his medications and look after himself with healthy food and a careful lifestyle, he could have a long, happy life, with even a wife and children. After hearing this, the little boy squeezed his eyes shut and was quiet for a long while. He then opened his eyes, nodded to himself, and promptly said: “Okay, so how much further to the circus?”


A Closer Look at Accommodation Solutions: JAN's Solution Showcase
Workplace accommodations for workers with disabilities come in many forms, ranging from the simple to the technical. They can involve digital technology, changes to a workstation, or specialized productivity tools. Regardless, these adjustments to where, when, or how work is done enable qualified individuals with disabilities to perform the essential functions of a job.
A number of common and effective accommodations are featured in the Job Accommodation Network's (JAN) latest Solution Showcase — a video series highlighting productivity enhancements for workers with a variety of disabilities. Each short video addresses a particular accommodation solution, illustrating the "why and how" of the tactic.
The newest Solution Showcase videos explore color coding, adjustable workstations, and more. Color coding—which can assist those who face difficulties with organization, prioritization, and memory—can entail using colored post-it notes, paper clips, folders, and binder tabs. The adjustable workstations video showcases sit-and-stand desks and other office and industrial workstations.
You can find these new videos on JAN's website, along with all the videos in the helpful series.
JAN is funded by a contract from the U.S. Department of Labor's Office of Disability Employment Policy.


Commercial and residential real estate owners should consider purchasing flood insurance, even if the property is not in a high-risk or flood-prone area. Floods can occur at almost any location from events such as a fast, heavy rainfall; blocked storm drain; or an overflowing stream.
Flood insurance generally covers your home and its foundation; plumbing and electrical systems; central air and heating systems; cabinets; and a detached garage. Some policies also will cover personal belongings, such as clothing and furniture.
Flood insurance is typically not included under standard homeowners’, renters’ or commercial property insurance policies.
Flood insurance is generally purchased through the National Flood Insurance Program, administered through the Federal Emergency Management Agency (FEMA) or private insurers.


Thieves may have gotten to the carcass of a sperm whale that recently washed ashore on a Bali beach first, after officials reported all of its teeth missing and pointed to a lack of awareness among the public about the protected specie
The twilight zone contains the largest biomass of the world’s ocean. Identifying its role in the trophic supply and contaminant exposure of marine megafauna constitutes a critical challenge in the context of global change. The white shark (Carcharodon carcharias) is a threatened species with some of the highest concentrations of neurotoxin methylmercury (MeHg) among marine top predators. Large white sharks migrate seasonally from coastal habitats, where they primarily forage on pinnipeds, to oceanic offshore habitats. Tagging studies suggest that while offshore, white sharks may forage at depth on mesopelagic species, yet no biochemical evidence exists. Here, we used mercury isotopic composition to assess the dietary origin of MeHg contamination in white sharks from the Northeast Pacific Ocean. We estimated that a minimum of 72% of the MeHg accumulated by white sharks originates from the consumption of mesopelagic prey, while a maximum of 25% derives from pinnipeds. In addition to highlighting the potential of mercury isotopes to decipher the complex ecological cycle of marine predators, our study provides evidence that the twilight zone constitutes a crucial foraging habitat for these large predators, which had been suspected for over a decade. Climate change is predicted to expand the production of mesopelagic MeHg and modify the mesopelagic biomass globally. Considering the pivotal role of the twilight zone is therefore essential to better predict both MeHg exposure and trophic supply to white sharks, and effectively protect these key vulnerable predators.
Oceana regrets that the Fisheries Bill, which has today received Royal Assent making it the Fisheries Act, fails to include a legal duty to fish sustainably, below Maximum Sustainable Yield (MSY), for all stocks. The Fisheries Bill originally offered hope of a new gold standard for fisheries management in the UK, which could have served as an example across the globe. It could
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Integrating your curated content to your website or blog will allow you to increase your website visitors’ engagement, boost SEO and acquire new visitors. By redirecting your social media traffic to your website, Scoop.it will also help you generate more qualified traffic and leads from your curation work.
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In its report ‘The European market for savoury snacks to 2006’ Datamonitor said the UK accounted for almost half of the $4bn European savoury snacks market with consumers spending $28.40 per head in 2001, in return for this they received 3.4 kg of snacks each.
The total European market had grown by over $1bn since 1996, representing a 74.5% rise in value, due largely to innovation within this sector and is expected to grow to a value of $5bn by 2006.


One of the primary questions in CF is the so called
q 1 sproblem. In a D/T mixture, some fraction of the muons captured in theexcited state of muonic deuterium can be transferred to the triton beforereaching the ground state with the probability (1-
There has been a longstanding discrepancy between theoretical predictions,based on semi-classical calculations, and experimental data derivedindirectly (see for example, Ref. [1,36]). Recentexperimental developments [37,38] using state-of-the-art Xray detection technologies are producing more direct information about
q 1 s
Processes involving excited states,
n>1, of the muonic atom have gainedincreasing theoretical attention. In addition to semi-classicalcalculations of excited transfer reactions [39,40], fullquantal calculations are emerging [41] using the hypersphericalapproach (Section 2.1.4). The transport cross sectionsof excited atoms including Stark transitions are being investigated mainlyin semi-classical approaches [42,43].
Recently, a new process has been suggested by Froelich andWallenius [44,45,46]. They predict a high rate offormation of a muonically excited metastable three-body state (associated with the adiabatic 3potential [47]) in thecollision of excited with D
2, which will then decay into,effectively reversing the transfer reaction:
We note that the side path model is unlikely to impact our measurements using emitted from layers, since the Ramsauer-Townsend effect is not expected for excited muonic atoms.